The freshwater planarian Schmidtea mediterranea: embryogenesis, stem cells and regeneration

Overview
TitleThe freshwater planarian Schmidtea mediterranea: embryogenesis, stem cells and regeneration
AuthorsSánchez Alvarado A
TypeJournal Article
Journal NameCurrent opinion in genetics & development
Volume13
Issue4
Year2003
Page(s)438-44
CitationSánchez Alvarado A. The freshwater planarian Schmidtea mediterranea: embryogenesis, stem cells and regeneration. Current opinion in genetics & development. 2003 Aug; 13(4):438-44.

Abstract

Planarians have been used as a model to study development and regeneration for more than 200 years. Research on these animals has traditionally focused on surgical and pharmacological manipulations. Recently, the dissection of planarians has become more molecular in nature. The isolation of thousands of expressed sequence tags and the introduction of in situ hybridizations, immunocytology, and RNA-mediated gene interference has opened the door to gene discovery and to the study of gene function in planarians during development and regeneration. These advances promise to shed mechanistic insight into basic biological attributes such as regeneration and stem-cell regulation.

Properties
Additional details for this publication include:
Property NameValue
Journal CountryEngland
Publication ModelPrint
Publication TypeJournal Article
Language Abbreng
LanguageEnglish
Journal AbbreviationCurr. Opin. Genet. Dev.
Publication Date2003 Aug
pISSN0959-437X
ISSN0959-437X
Publication TypeResearch Support, U.S. Gov't, P.H.S.
Publication TypeReview
Cross References
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DatabaseAccession
PMID: PubMedPMID:12888018