pigment cup cell
▻ Planarian Anatomy Ontology Class Overview
▻ Embryonic Molecular Fate Mapping
▻ In Situ Hybridization Data
▻ Sequences
▻ PAGE: Planarian Anatomy Gene Expression
Planarian Anatomy Ontology Class Overview
For more information about the ontology visit PLANA Overview
NAME:
pigment cup cell
DEFINITON:
Non-neuronal, pigmented cells arrayed along the proximal side of the optic cup.
TERM DEFINITION CITATIONS:
PMID:22884275, PMID:21852957
TERM CITATIONS:
Expand publication list
- PMID:22445864
- PMID:22339734
- PMID:22884275
- PMID:29158443
- PMID:29674432
- PMID:17905225
- PMID:28976975
- PMID:27606067
- PMID:17390146
- PMID:25493551
- PMID:21458439
- PMID:30471994
- PMID:28495872
- PMID:17251262
- PMID:28287248
- PMID:21852957
- PMID:23318641
- PMID:28245923
- PMID:27122174
- PMID:27551436
- PMID:20967238
- PMID:23250205
- PMID:25254346
- PMID:28137894
- PMID:24063805
- PMID:17553481
- PMID:29674431
- PMID:21282632
- PMID:26017970
TERM ID:
PLANA:0000031
ABOUT THIS TERM:
pigment cup cell
↳is a material entity and neuron associated cell (sensu Nematoda and Protostomia) ↳contained in head region, dorsal region of the whole animal and anterior region of the whole animal
↳develops from trail cell
↳existence overlaps juvenile stage, asexual adult, adult hermaphrodite, Stage 8 and Stage 7
↳existence starts during or after Stage 7
↳part of optic cup
→ melanosome part of pigment cup cell
BROWSE PLANARIAN ONTOLOGY TREE (IN OLS):
Click on the '-' and '+' to collapse and expand term 'is a' and 'part of' relationships.
EXPLORE ONTOLOGY GRAPH:
Dynamically explore this term by selecting additional relationships to display (checkboxes on the right). Expand nodes by double-clicking on it . Single-click on a node to display the definition below the graph.
Embryonic Molecular Fate Mapping
All experimental data displayed here is from Davies et. al., 2017, Smed Embryogenesis Molecular Staging Resource
IN SITU HYBRIDIZATION DATA:
Smed ID Accession Name Alias Expressed during stage(s) Tissue/Pattern Images SMED30018592 AFP48372.1 ovo ovo Stage 6, Stage 7, Stage 8 trail cell, photoreceptor neuron, optic cup, pigment cup cell, visual system, eye 
SMED30006796 AFC87780.1 tyrosinase tyrosinase Stage 7, Stage 8 optic cup, pigment cup cell, visual system, eye 
Click to see image symbols and abbreviations
Abbreviation or symbol Definition O oral hemisphere A aboral hemisphere D dorsal V ventral L lateral black arrowhead embryonic pharynx red arrowhead definitive pharynx black arrows primitive gut yellow arrows primitive ectoderm cells cyan arrows brain cyan arrowheads nerve cords blue arrowheads eye progenitors (trail cells) purple arrowheads eyes scale bar 100 µm
SEQUENCES:
smed_20140614 transcript sequences for genes validated by in situ hybridization (above).
>SMED30006796 ID=SMED30006796|Name=tyrosinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1755bp
TGTCAGTTTAGTCATGCTCGTAATCACAATAGGCATAGTCTTTGCATCTTTCTTACCTTTGAGTGACTGCCTAATCCCAA
GGATTTGCAGTAGGAATGTCACTCTTTCTAATTCAACATGTTGTCCAATTTATAATGATTTTGTTTGCGGTGGTCCTTTT
CGTGGATCTTGTGAAGTCTCCATTCTTTTTCAAAATCACACTGAGCACTCGGATGTTATCACCGGAAAATTGGAAAATGA
CGACAGACTCAACTGGCCATCAAGATTTTTTAAATTTCTTTGCAGTTGCAAGTCAAACTATGATGGAATAGCCTGTGACA
AGTGTAAATCAGGGTGGCAAGGGGAAAACTGTGAGGTGGTCTCCCCGAGAAAGATTAGACAAAATATTCTTAACATGAGA
TCATACGATGTTTTTATTTTTTTATCGATACTGAACATCAGCAAATATCAGTTGGCCGATTTCCTGATCACAAATTCGTC
CTCAAACCTTCACTGTGACCCTGTCAATGAAGACAACATTCAATTGGTCAATGCTTCCATTTATGATACAATGGTTTACT
TACATTTCTATGCGTCCAGGAGTACAATGTCTAAAGAACTTATGGAATCCTGCACAGACAAGGATAACAAATTAGACTTC
GCTCATAAAGGTCCAGCTTTTTTTACATGGCACCGACATTATTTACTGATGTTTGAAGACTTATTAAGGAGTATTGCAGT
CGAACAATTTGGATATTATAATTTCACATTACCATATTGGGACTGGACGAATCAAATAACTTGTAATATATGTACAAATG
ACTTACTTGGCGATATTCCCACTGAAGATCAAGAATCTAACAGCACATTTTTTAAATGGAAACCGATTTGCCCTCAGAAA
CCTAACGATTTTGATTGTCATATTTGCGATCCAAGCCAGGAAGAACCTTTTTTATGGAGAAAATACTCATCAACGGTAGA
CAGACTTCCTAATCAGAACGAAATTGATGAGTTATTCTCAATCAACCAATATGATTCGGAGCCCTTCAATTCCAGCTCAT
TTAGTAGGAAAAGCTTTCGGAATTTTGCAGAGGGATATTATCGAGTTCATCCAAACTCAGATGATATGAAAATGAAAGAC
ATTGGGAAGGGACTCCCCCATCAAAATATCATGATGCATAATATGTTTTATCAATGGAACTTGGATGGATTTCACAACGA
GTCCCAATGATCCATTATTTCTACTACATCATACGTTTATGGACAAAATCTTTGAAATTTGGCTATTAAGAAATAGACGA
TCTACATACCCTGGGAAATCTTCAACACCAATCGGGCAGCATGCTGACGATTTTATTGTGCCTTTCCTTCCACTAATCAG
AAACAGGAATTTGTTTACTTCAGCAAATGAATTTGGCTACGCCTACGATAACAATATTGTTGGAAATAAATTGTTCACAA
ATCATCAACTAGATTTCGAAAAGAGCTCATCGGAAATTTACTACATCCTAACGGCAGTTGCCTTTGTAGTACTAGTTGCG
ATCGTCGTCGGATTGTACTGCTTCAGACCCAGTCAAATCAGTCACACGGCTTATGAATTCATTGAAGACCAGGAGCAGGA
GGAAAAGACAAATTACTTTAACAACAATGAAAAAATGCCTCTACTGAAATGACAAGCCATTTCTGATGACTATTATAATA
TTGTCACCTTAAATTTTCTTTGAAACAACTTTATTATTGACAAATTTTGAAGAATCCTTTTAAGCAAAATAAAGT
>SMED30018592 ID=SMED30018592|Name=ovo|organism=Schmidtea mediterranea sexual|type=transcript|length=1211bp
GTCATATTGAACACTGAGACTAGCTATCAATAGCTGACAATTAGACGTATAAAATGTTAGGGTACGCCTTTTTGGCCATT
ATTTCACACCAAAATTTCCATGAGTATTTTTCTAATAAGCACTCTACTCGCAAACGATGACGAAATGCCCACAGATTTGT
CATCGAAAACTGAAAAGATTGAAAACCATGAAAAATCTGAAAGGAATCTCTGCAAGTATTCCAGTCAGTTTCTTTCCTGT
TTTTATTCACAGGAAATGTTGACACTACTTATGAGAAAAAATTTCATCAATCAATATTCATTTTATTTAAAGATTTTCTC
GGGGTTTCCACAATTCGTCGATAACTTCAACTTAGTAAATCCAACAGATTTCACCGTCAATTCAAATTCAACAACAATTT
TGCCCTCATTCAACTTCCATAAAACGTCATTGAATATCGAAATGAACACCTCACTGGCCAATTCTTCAAGCACTGGTAGG
TCGTCTCCAACTGAAACTGTGTCTGAAAATCTTTGGTTAGAAAAAGTAAAGGTGGAAAAATATTTCCATTTAATTGAAAA
TCTATCACAATCCCAAGAGAACATTGAAGACATTGTCAAAACGATCAAAGTCAAACGAAGAAATTTTGCTGAATATATTA
AGAAACTTTACCTAAGTGATCCAGCCAAATTTAAGTTGACAAATGGTGGAGATGGAATAGTAAATCCATTTAGAAAACAA
TTCAAAGAAGAACGAGATAAATCTATGGACAAATTTTGCATCGAAGTTAATCACAATTATCAATGTAAGATATGTAACAA
GGTGTTTCCTTCCAAAAAGCACATGCAACGTCATATACGTTCACACGGTGTAAATTTTGATTGGTTGTGTAAATATTGTT
TTAAACCGTTTATTGATTCCTACGATTTAAAACGACATACGAGAGTCCATACAGGAGTTCAACCATACAAATGTCAAAGT
TGCACAAGAAAATTCAGTCAACGATGCTCATTGGAAAGTCATCAGGTGAAAATCCATGGAGTAGCACTGAATTATCTATA
CAAAGAAAGAAGGAACAAGTTGTATCCGTGTGAAATCTGCAGTTATAGTACGTCTTGTAAAGCAACTTGGTTGAGTCACA
TCATTCAGGAGCACCCGAATTCACTTTATGCAAAAGAAGAAGCACTCAAAGGAAAATACAACTGACTTTGAAAAATATTG
ATTTTTCAAGC
PAGE: Planarian Anatomy Gene Expression
These transcripts were reported as being expressed in pigment cup cell. Click this link to learn more about PAGE.
PAGE Curations: 13
PLANA Term Reference Transcript Description Gene Models Published Transcript Transcriptome Publication Specimen Lifecycle Evidence pigment cup cell SMED30012020 tph SMESG000000522.1 SMESG000000520.1 tph smed_ncbi_20200123 PMID:22451003
González-Sastre et al., 2012 
pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 SMED30006796 smed_20140614 PMID:28072387
Davies et al., 2017 
pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 SMED30006796 smed_20140614 PMID:28072387
Davies et al., 2017 
pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 tyrosinase smed_ncbi_20200123 PMID:28072387
Davies et al., 2017 pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 tyrosinase smed_ncbi_20200123 PMID:28072387
Davies et al., 2017 pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 AFC87780.1 smed_ncbi_20200123 PMID:28072387
Davies et al., 2017 pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 AFC87780.1 smed_ncbi_20200123 PMID:28072387
Davies et al., 2017 pigment cup cell SMED30011934 sp6-9 SMESG000050160.1 JN983830.1 smed_ncbi_20200123 PMID:28976975
Su et al., 2017 
pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 tyrosinase smed_ncbi_20200123 PMID:21852957
Lapan et al., 2011 pigment cup cell SMED30009712 epidermal growth factor receptor 1 SMESG000070834.1 HM777018.1 smed_ncbi_20200123 PMID:27122174
Barberán et al., 2016 pigment cup cell SMED30009712 epidermal growth factor receptor 1 SMESG000070834.1 HM777018 smed_ncbi_20200123 PMID:27122174
Barberán et al., 2016 pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 JN983828 smed_ncbi_20200123 PMID:28245923
LoCascio et al., 2017 pigment cup cell SMED30006796 tyrosinase SMESG000065741.1 Smed-tyrosinase smed_ncbi_20200123 PMID:28245923
LoCascio et al., 2017
Note: Hover over icons to view figure legend
↳contained in head region, dorsal region of the whole animal and anterior region of the whole animal
↳develops from trail cell
↳existence overlaps juvenile stage, asexual adult, adult hermaphrodite, Stage 8 and Stage 7
↳existence starts during or after Stage 7
↳part of optic cup
→ melanosome part of pigment cup cell
BROWSE PLANARIAN ONTOLOGY TREE (IN OLS):
Click on the '-' and '+' to collapse and expand term 'is a' and 'part of' relationships.
EXPLORE ONTOLOGY GRAPH:
Dynamically explore this term by selecting additional relationships to display (checkboxes on the right). Expand nodes by double-clicking on it . Single-click on a node to display the definition below the graph.
Embryonic Molecular Fate Mapping
All experimental data displayed here is from Davies et. al., 2017, Smed Embryogenesis Molecular Staging Resource
IN SITU HYBRIDIZATION DATA:
| Smed ID | Accession | Name | Alias | Expressed during stage(s) | Tissue/Pattern | Images |
|---|---|---|---|---|---|---|
| SMED30018592 | AFP48372.1 | ovo | ovo | Stage 6, Stage 7, Stage 8 | trail cell, photoreceptor neuron, optic cup, pigment cup cell, visual system, eye | |
| SMED30006796 | AFC87780.1 | tyrosinase | tyrosinase | Stage 7, Stage 8 | optic cup, pigment cup cell, visual system, eye | |
Click to see image symbols and abbreviations
| Abbreviation or symbol | Definition |
|---|---|
| O | oral hemisphere |
| A | aboral hemisphere |
| D | dorsal |
| V | ventral |
| L | lateral |
| black arrowhead | embryonic pharynx |
| red arrowhead | definitive pharynx |
| black arrows | primitive gut |
| yellow arrows | primitive ectoderm cells |
| cyan arrows | brain |
| cyan arrowheads | nerve cords |
| blue arrowheads | eye progenitors (trail cells) |
| purple arrowheads | eyes |
| scale bar | 100 µm |
SEQUENCES:
smed_20140614 transcript sequences for genes validated by in situ hybridization (above).
>SMED30006796 ID=SMED30006796|Name=tyrosinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1755bp
TGTCAGTTTAGTCATGCTCGTAATCACAATAGGCATAGTCTTTGCATCTTTCTTACCTTTGAGTGACTGCCTAATCCCAA
GGATTTGCAGTAGGAATGTCACTCTTTCTAATTCAACATGTTGTCCAATTTATAATGATTTTGTTTGCGGTGGTCCTTTT
CGTGGATCTTGTGAAGTCTCCATTCTTTTTCAAAATCACACTGAGCACTCGGATGTTATCACCGGAAAATTGGAAAATGA
CGACAGACTCAACTGGCCATCAAGATTTTTTAAATTTCTTTGCAGTTGCAAGTCAAACTATGATGGAATAGCCTGTGACA
AGTGTAAATCAGGGTGGCAAGGGGAAAACTGTGAGGTGGTCTCCCCGAGAAAGATTAGACAAAATATTCTTAACATGAGA
TCATACGATGTTTTTATTTTTTTATCGATACTGAACATCAGCAAATATCAGTTGGCCGATTTCCTGATCACAAATTCGTC
CTCAAACCTTCACTGTGACCCTGTCAATGAAGACAACATTCAATTGGTCAATGCTTCCATTTATGATACAATGGTTTACT
TACATTTCTATGCGTCCAGGAGTACAATGTCTAAAGAACTTATGGAATCCTGCACAGACAAGGATAACAAATTAGACTTC
GCTCATAAAGGTCCAGCTTTTTTTACATGGCACCGACATTATTTACTGATGTTTGAAGACTTATTAAGGAGTATTGCAGT
CGAACAATTTGGATATTATAATTTCACATTACCATATTGGGACTGGACGAATCAAATAACTTGTAATATATGTACAAATG
ACTTACTTGGCGATATTCCCACTGAAGATCAAGAATCTAACAGCACATTTTTTAAATGGAAACCGATTTGCCCTCAGAAA
CCTAACGATTTTGATTGTCATATTTGCGATCCAAGCCAGGAAGAACCTTTTTTATGGAGAAAATACTCATCAACGGTAGA
CAGACTTCCTAATCAGAACGAAATTGATGAGTTATTCTCAATCAACCAATATGATTCGGAGCCCTTCAATTCCAGCTCAT
TTAGTAGGAAAAGCTTTCGGAATTTTGCAGAGGGATATTATCGAGTTCATCCAAACTCAGATGATATGAAAATGAAAGAC
ATTGGGAAGGGACTCCCCCATCAAAATATCATGATGCATAATATGTTTTATCAATGGAACTTGGATGGATTTCACAACGA
GTCCCAATGATCCATTATTTCTACTACATCATACGTTTATGGACAAAATCTTTGAAATTTGGCTATTAAGAAATAGACGA
TCTACATACCCTGGGAAATCTTCAACACCAATCGGGCAGCATGCTGACGATTTTATTGTGCCTTTCCTTCCACTAATCAG
AAACAGGAATTTGTTTACTTCAGCAAATGAATTTGGCTACGCCTACGATAACAATATTGTTGGAAATAAATTGTTCACAA
ATCATCAACTAGATTTCGAAAAGAGCTCATCGGAAATTTACTACATCCTAACGGCAGTTGCCTTTGTAGTACTAGTTGCG
ATCGTCGTCGGATTGTACTGCTTCAGACCCAGTCAAATCAGTCACACGGCTTATGAATTCATTGAAGACCAGGAGCAGGA
GGAAAAGACAAATTACTTTAACAACAATGAAAAAATGCCTCTACTGAAATGACAAGCCATTTCTGATGACTATTATAATA
TTGTCACCTTAAATTTTCTTTGAAACAACTTTATTATTGACAAATTTTGAAGAATCCTTTTAAGCAAAATAAAGT
>SMED30018592 ID=SMED30018592|Name=ovo|organism=Schmidtea mediterranea sexual|type=transcript|length=1211bp
GTCATATTGAACACTGAGACTAGCTATCAATAGCTGACAATTAGACGTATAAAATGTTAGGGTACGCCTTTTTGGCCATT
ATTTCACACCAAAATTTCCATGAGTATTTTTCTAATAAGCACTCTACTCGCAAACGATGACGAAATGCCCACAGATTTGT
CATCGAAAACTGAAAAGATTGAAAACCATGAAAAATCTGAAAGGAATCTCTGCAAGTATTCCAGTCAGTTTCTTTCCTGT
TTTTATTCACAGGAAATGTTGACACTACTTATGAGAAAAAATTTCATCAATCAATATTCATTTTATTTAAAGATTTTCTC
GGGGTTTCCACAATTCGTCGATAACTTCAACTTAGTAAATCCAACAGATTTCACCGTCAATTCAAATTCAACAACAATTT
TGCCCTCATTCAACTTCCATAAAACGTCATTGAATATCGAAATGAACACCTCACTGGCCAATTCTTCAAGCACTGGTAGG
TCGTCTCCAACTGAAACTGTGTCTGAAAATCTTTGGTTAGAAAAAGTAAAGGTGGAAAAATATTTCCATTTAATTGAAAA
TCTATCACAATCCCAAGAGAACATTGAAGACATTGTCAAAACGATCAAAGTCAAACGAAGAAATTTTGCTGAATATATTA
AGAAACTTTACCTAAGTGATCCAGCCAAATTTAAGTTGACAAATGGTGGAGATGGAATAGTAAATCCATTTAGAAAACAA
TTCAAAGAAGAACGAGATAAATCTATGGACAAATTTTGCATCGAAGTTAATCACAATTATCAATGTAAGATATGTAACAA
GGTGTTTCCTTCCAAAAAGCACATGCAACGTCATATACGTTCACACGGTGTAAATTTTGATTGGTTGTGTAAATATTGTT
TTAAACCGTTTATTGATTCCTACGATTTAAAACGACATACGAGAGTCCATACAGGAGTTCAACCATACAAATGTCAAAGT
TGCACAAGAAAATTCAGTCAACGATGCTCATTGGAAAGTCATCAGGTGAAAATCCATGGAGTAGCACTGAATTATCTATA
CAAAGAAAGAAGGAACAAGTTGTATCCGTGTGAAATCTGCAGTTATAGTACGTCTTGTAAAGCAACTTGGTTGAGTCACA
TCATTCAGGAGCACCCGAATTCACTTTATGCAAAAGAAGAAGCACTCAAAGGAAAATACAACTGACTTTGAAAAATATTG
ATTTTTCAAGC
PAGE: Planarian Anatomy Gene Expression
These transcripts were reported as being expressed in pigment cup cell. Click this link to learn more about PAGE.
PAGE Curations: 13
| PLANA Term | Reference Transcript | Description | Gene Models | Published Transcript | Transcriptome | Publication | Specimen | Lifecycle | Evidence |
|---|---|---|---|---|---|---|---|---|---|
| pigment cup cell | SMED30012020 | tph | SMESG000000522.1 SMESG000000520.1 | tph | smed_ncbi_20200123 | PMID:22451003 González-Sastre et al., 2012 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | SMED30006796 | smed_20140614 | PMID:28072387 Davies et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | SMED30006796 | smed_20140614 | PMID:28072387 Davies et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | tyrosinase | smed_ncbi_20200123 | PMID:28072387 Davies et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | tyrosinase | smed_ncbi_20200123 | PMID:28072387 Davies et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | AFC87780.1 | smed_ncbi_20200123 | PMID:28072387 Davies et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | AFC87780.1 | smed_ncbi_20200123 | PMID:28072387 Davies et al., 2017 | | | |
| pigment cup cell | SMED30011934 | sp6-9 | SMESG000050160.1 | JN983830.1 | smed_ncbi_20200123 | PMID:28976975 Su et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | tyrosinase | smed_ncbi_20200123 | PMID:21852957 Lapan et al., 2011 | | | |
| pigment cup cell | SMED30009712 | epidermal growth factor receptor 1 | SMESG000070834.1 | HM777018.1 | smed_ncbi_20200123 | PMID:27122174 Barberán et al., 2016 | | | |
| pigment cup cell | SMED30009712 | epidermal growth factor receptor 1 | SMESG000070834.1 | HM777018 | smed_ncbi_20200123 | PMID:27122174 Barberán et al., 2016 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | JN983828 | smed_ncbi_20200123 | PMID:28245923 LoCascio et al., 2017 | | | |
| pigment cup cell | SMED30006796 | tyrosinase | SMESG000065741.1 | Smed-tyrosinase | smed_ncbi_20200123 | PMID:28245923 LoCascio et al., 2017 | | | |
