DNA primase large subunit

Overview
NameDNA primase large subunit
Smed IDSMED30036024
Length (bp)1636
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DNA primase large subunit (SMED30036024) t-SNE clustered cells

Violin plots show distribution of expression levels for DNA primase large subunit (SMED30036024) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of DNA primase large subunit (SMED30036024) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for DNA primase large subunit (SMED30036024) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30036024

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 10

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30036024h1SMcG0001766 SmedASXL_016118SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30036024h1SMcG0001766 SmedASXL_016118SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30036024h1SMcG0001766 dd_Smed_v4_13727_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30036024h1SMcG0001766 dd_Smed_v6_13727_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
zeta neoblastSMED30036024h1SMcG0001766 dd_Smed_v4_13727_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
neoblastSMED30036024h1SMcG0001766 SMED_32947_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30036024h1SMcG0001766 SMED_02252_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30036024h1SMcG0007237 SMED_02252_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30036024h1SMcG0007238 SMED_02252_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30036024h1SMcG0007238 SMED_32947_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DNA primase large subunit vs. Ensembl Human
Match: PRIM2 (DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370])

HSP 1 Score: 360.533 bits (924), Expect = 2.309e-118
Identity = 187/443 (42.21%), Postives = 284/443 (64.11%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNII---------------IYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PP++ + L   ENLAIDR+K+L+ ++NL   YVKG  +Y  ++ S L KL    K+       D  +    D +SH+ILR+AYC ++EL +WFI QE+DL ++RF+   +     I+ F+ D+ +   EA+  E K    +    I+               IYK+PF   LDL + +KV L  GFA++   DI +++L  FR+ LS+ L+     +  +  ++RL P+L++L+  Y G+DYS+  N+ KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F + K D + F K Y+YNIRHS+G+EGKR +Y P+SC+KII SNPP  GD HGCPF+HS+ EL+ Q L+ +   +   I  I+  +K   +Q++C+ YF+++H + D+   ++NHPN++F ES++IL
Sbjct:   26 LQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFS---ILPKDKIQDFLKDSQLQF-EAISDEEKT---LREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLKQKLQSY-KISPGGISQILDLVKGTHYQVACQKYFEMIHNV-DDCGFSLNHPNQFFCESQRIL 455
[Close]
BLAST of DNA primase large subunit vs. Ensembl Human
Match: PRIM2 (DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370])

HSP 1 Score: 239.58 bits (610), Expect = 5.240e-71
Identity = 108/221 (48.87%), Postives = 162/221 (73.30%), Query Frame = 3 
Query:  699 IDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            +  ++RL P+L++L+  Y G+DYS+  N+ KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F + K D + F K Y+YNIRHS+G+EGKR +Y P+SC+KII SNPP  GD HGCPF+HS+ EL+ Q L+ +   +   I  I+  +K   +Q++C+ YF+++H + D+   ++NHPN++F ES++IL   
Sbjct:  326 VQSDERLQPLLNHLSHSYTGQDYSTQGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLKQKLQSY-KISPGGISQILDLVKGTHYQVACQKYFEMIHNV-DDCGFSLNHPNQFFCESQRILNGG 544

HSP 2 Score: 125.946 bits (315), Expect = 4.342e-30
Identity = 78/214 (36.45%), Postives = 123/214 (57.48%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQ---IDNTNII---------IYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELS 674
            LQFY  PP++ + L   ENLAIDR+K+L+ ++NL   YVKG  +Y  ++ S L KL    K+       D  +    D +SH+ILR+AYC ++EL +WFI QE+DL ++RF+   +     I+ F+ D+ +   EA+  E K   +   + ++  +         IYK+PF   LDL + +KV L  GFA++   DI +++L  FR+ LS+ L+
Sbjct:   26 LQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFS---ILPKDKIQDFLKDSQLQF-EAISDEEKTLREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALA 231
[Close]
BLAST of DNA primase large subunit vs. Ensembl Human
Match: PRIM2 (DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370])

HSP 1 Score: 105.531 bits (262), Expect = 9.415e-27
Identity = 45/75 (60.00%), Postives = 61/75 (81.33%), Query Frame = 3 
Query:  750 YLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF 974
            Y G+DYS+  N+ KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F
Sbjct:    4 YTGQDYSTQGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEF 78
[Close]
BLAST of DNA primase large subunit vs. Ensembl Human
Match: PRIM2 (DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370])

HSP 1 Score: 98.2117 bits (243), Expect = 1.797e-23
Identity = 49/112 (43.75%), Postives = 72/112 (64.29%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFN 404
            LQFY  PP++ + L   ENLAIDR+K+L+ ++NL   YVKG  +Y  ++ S L KL    K+       D  +    D +SH+ILR+AYC ++EL +WFI QE+DL ++RF+
Sbjct:   26 LQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFS 133
[Close]
BLAST of DNA primase large subunit vs. Ensembl Human
Match: PRIM2 (DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC:9370])

HSP 1 Score: 98.2117 bits (243), Expect = 1.797e-23
Identity = 49/112 (43.75%), Postives = 72/112 (64.29%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFN 404
            LQFY  PP++ + L   ENLAIDR+K+L+ ++NL   YVKG  +Y  ++ S L KL    K+       D  +    D +SH+ILR+AYC ++EL +WFI QE+DL ++RF+
Sbjct:   26 LQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFS 133
[Close]
BLAST of DNA primase large subunit vs. Ensembl Celegans
Match: pri-2 (DNA primase large subunit [Source:UniProtKB/Swiss-Prot;Acc:O02334])

HSP 1 Score: 250.751 bits (639), Expect = 1.672e-76
Identity = 156/444 (35.14%), Postives = 242/444 (54.50%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFV-----SNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAER-------LANPH-SIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNL-NKRYLGKDYSSANNMDKI--TADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPD-NYPITINHPNEYFEESRKIL 1349
            LQ Y  PP D + L   +++A++RLK+L+  +NL +        Y+D+   +  KL    K  V          ++ +    D + H+ILR+A+C T E  KW    E D  ++R   ER       LAN + +I+K  +     + E L A  + F   +  N   YKV F+  ++L++   V L KGFA+    D+ ++++   ++ +   ++    H+  ++EE RL+P LS L N  Y GKDY+       I  T   ID LS +SF PCM+ +++ L+ + H+K+  R QYGLFLKGIG+ L+E++   +  F +K  S+ F K+Y YNIR+ YG+EG+RV     SC  II  NPP A DCHGCPF+HS  +++ Q L   A    EQIE I    ++ Q+  +C  YF+ +H L +      I HPN+++EES+KI+
Sbjct:   41 LQLYQTPPGDDISLTEFDDIAMERLKLLKSFENLKDSVSL----YNDEFKDKFRKLCDGTKLIVFPDQKPPHQEEVYELWRRDNIGHFILRLAFCRTPENQKWLTQIEGDFLRFRLRQEREQVLDSALANVNFTIEKLGYTEKQAMIEDLEAACQ-FNLFEAPNKTFYKVDFIDAIELIRRGSVHLKKGFAYFPFDDLVTILVTKMKNNMMAAMARSFKHLAILEEEGRLLPRLSLLSNNAYSGKDYNGEQPDGSIIVTRHMIDKLSRRSFAPCMKQMHNHLRVNHHLKYGARRQYGLFLKGIGLSLDEAIAMMRDEFTKKITSDKFDKEYGYNIRYMYGKEGRRVAQTAMSCATIILRNPPSAVDCHGCPFRHSEKQVLKQKLGSDAILKKEQIERIAELAELNQYDKACTRYFEFMHNLEEGGLGQLITHPNQFYEESQKIV 479
[Close]
BLAST of DNA primase large subunit vs. Ensembl Celegans
Match: pri-2 (DNA primase large subunit [Source:UniProtKB/Swiss-Prot;Acc:O02334])

HSP 1 Score: 250.751 bits (639), Expect = 1.672e-76
Identity = 156/444 (35.14%), Postives = 242/444 (54.50%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFV-----SNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAER-------LANPH-SIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNL-NKRYLGKDYSSANNMDKI--TADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPD-NYPITINHPNEYFEESRKIL 1349
            LQ Y  PP D + L   +++A++RLK+L+  +NL +        Y+D+   +  KL    K  V          ++ +    D + H+ILR+A+C T E  KW    E D  ++R   ER       LAN + +I+K  +     + E L A  + F   +  N   YKV F+  ++L++   V L KGFA+    D+ ++++   ++ +   ++    H+  ++EE RL+P LS L N  Y GKDY+       I  T   ID LS +SF PCM+ +++ L+ + H+K+  R QYGLFLKGIG+ L+E++   +  F +K  S+ F K+Y YNIR+ YG+EG+RV     SC  II  NPP A DCHGCPF+HS  +++ Q L   A    EQIE I    ++ Q+  +C  YF+ +H L +      I HPN+++EES+KI+
Sbjct:   41 LQLYQTPPGDDISLTEFDDIAMERLKLLKSFENLKDSVSL----YNDEFKDKFRKLCDGTKLIVFPDQKPPHQEEVYELWRRDNIGHFILRLAFCRTPENQKWLTQIEGDFLRFRLRQEREQVLDSALANVNFTIEKLGYTEKQAMIEDLEAACQ-FNLFEAPNKTFYKVDFIDAIELIRRGSVHLKKGFAYFPFDDLVTILVTKMKNNMMAAMARSFKHLAILEEEGRLLPRLSLLSNNAYSGKDYNGEQPDGSIIVTRHMIDKLSRRSFAPCMKQMHNHLRVNHHLKYGARRQYGLFLKGIGLSLDEAIAMMRDEFTKKITSDKFDKEYGYNIRYMYGKEGRRVAQTAMSCATIILRNPPSAVDCHGCPFRHSEKQVLKQKLGSDAILKKEQIERIAELAELNQYDKACTRYFEFMHNLEEGGLGQLITHPNQFYEESQKIV 479
[Close]
BLAST of DNA primase large subunit vs. Ensembl Celegans
Match: pri-2 (DNA primase large subunit [Source:UniProtKB/Swiss-Prot;Acc:O02334])

HSP 1 Score: 200.29 bits (508), Expect = 1.997e-59
Identity = 111/281 (39.50%), Postives = 168/281 (59.79%), Query Frame = 3 
Query:  519 NIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNL-NKRYLGKDYSSANNMDKI--TADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPD-NYPITINHPNEYFEESRKIL 1349
            N   YKV F+  ++L++   V L KGFA+    D+ ++++   ++ +   ++    H+  ++EE RL+P LS L N  Y GKDY+       I  T   ID LS +SF PCM+ +++ L+ + H+K+  R QYGLFLKGIG+ L+E++   +  F +K  S+ F K+Y YNIR+ YG+EG+RV     SC  II  NPP A DCHGCPF+HS  +++ Q L   A    EQIE I    ++ Q+  +C  YF+ +H L +      I HPN+++EES+KI+
Sbjct:   18 NKTFYKVDFIDAIELIRRGSVHLKKGFAYFPFDDLVTILVTKMKNNMMAAMARSFKHLAILEEEGRLLPRLSLLSNNAYSGKDYNGEQPDGSIIVTRHMIDKLSRRSFAPCMKQMHNHLRVNHHLKYGARRQYGLFLKGIGLSLDEAIAMMRDEFTKKITSDKFDKEYGYNIRYMYGKEGRRVAQTAMSCATIILRNPPSAVDCHGCPFRHSEKQVLKQKLGSDAILKKEQIERIAELAELNQYDKACTRYFEFMHNLEEGGLGQLITHPNQFYEESQKIV 298
[Close]
BLAST of DNA primase large subunit vs. Ensembl Celegans
Match: pri-2 (DNA primase large subunit [Source:UniProtKB/Swiss-Prot;Acc:O02334])

HSP 1 Score: 200.29 bits (508), Expect = 1.997e-59
Identity = 111/281 (39.50%), Postives = 168/281 (59.79%), Query Frame = 3 
Query:  519 NIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNL-NKRYLGKDYSSANNMDKI--TADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPD-NYPITINHPNEYFEESRKIL 1349
            N   YKV F+  ++L++   V L KGFA+    D+ ++++   ++ +   ++    H+  ++EE RL+P LS L N  Y GKDY+       I  T   ID LS +SF PCM+ +++ L+ + H+K+  R QYGLFLKGIG+ L+E++   +  F +K  S+ F K+Y YNIR+ YG+EG+RV     SC  II  NPP A DCHGCPF+HS  +++ Q L   A    EQIE I    ++ Q+  +C  YF+ +H L +      I HPN+++EES+KI+
Sbjct:   18 NKTFYKVDFIDAIELIRRGSVHLKKGFAYFPFDDLVTILVTKMKNNMMAAMARSFKHLAILEEEGRLLPRLSLLSNNAYSGKDYNGEQPDGSIIVTRHMIDKLSRRSFAPCMKQMHNHLRVNHHLKYGARRQYGLFLKGIGLSLDEAIAMMRDEFTKKITSDKFDKEYGYNIRYMYGKEGRRVAQTAMSCATIILRNPPSAVDCHGCPFRHSEKQVLKQKLGSDAILKKEQIERIAELAELNQYDKACTRYFEFMHNLEEGGLGQLITHPNQFYEESQKIV 298
[Close]
BLAST of DNA primase large subunit vs. Ensembl Fly
Match: DNApol-alpha60 (gene:FBgn0259676 transcript:FBtr0078241)

HSP 1 Score: 264.618 bits (675), Expect = 2.237e-81
Identity = 164/457 (35.89%), Postives = 256/457 (56.02%), Query Frame = 3 
Query:   39 SLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYF--VSNAGS-----DISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQ---EALPAEYKKFFQIDNTN--------IIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQN 1355
            SL  K   N +  Y+ PPT+ V +D  E LA++RL++LR +D  S   ++   +   ++ S       L  Y    S  GS     DI Q+   D LSH+ILR+AYC +++L++WF+A+E++LF+Y+F A    +   +K+F+  NG  +    EA   E K                 +  YKVPF QVLDLV+ ++  L  G+A++   D+ SLV    +  + Q L   +  + +++ ++R+   L  L+  Y G+DY+   +   +  + +D LS  S P CM+  +  ++ + H+KH GRMQYGLFLKGIGV LE+SL+FW++ F +K D++ F + Y YNI H+YG++G  VNY PYSC KII  +    GDCHGCP+++ +   +   L  +  + S  I+ ++  +    +QI C  YF+L H  P     +INHPN YFEES+  + N
Sbjct:   19 SLETKYPHN-VMLYHYPPTEDVHIDEFEELALERLRLLRVLDRASTRNLRVLSDEWKEIVSADLTREGLRSYLRLCSTGGSAKHEADI-QTRRRDYLSHFILRLAYCRSEDLARWFVAREMELFRYKFAA---LSSFEVKQFLEANGFEIHPLTEAQKDEVKDGLYESTVGQSVAKIELLDFYKVPFTQVLDLVRGRRCFLKAGYAYVNTHDLVSLVGTKQQDEIEQGLQAAKTMVEDVEADERISRTLKALHNSYTGRDYTVCRDA-AVPIESLDQLSKTSMPLCMRMCHEHIRANHHIKHSGRMQYGLFLKGIGVALEDSLRFWREEFTKKMDADKFTRSYEYNIYHNYGKKGSMVNYTPYSCAKII-KDVAGPGDCHGCPYKNMDQGSLKTKLSSYGLSAS-AIDEVMFFVSRGHYQIGCGKYFQLTHNSP--VEPSINHPNNYFEESQIAMGN 465
[Close]
BLAST of DNA primase large subunit vs. Ensembl Zebrafish
Match: prim2 (DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-050522-471])

HSP 1 Score: 347.821 bits (891), Expect = 1.119e-113
Identity = 184/445 (41.35%), Postives = 280/445 (62.92%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKL-----STLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQ------------IDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PP D + L   E  A++RLK+L+ ++NL   YVK   +Y  ++ +    L     + +    V    S+  +   D I SH+ILR+AYC T++L +WFI QE+DLF+YRF    L++ H  + F+  N +   E + AE KK+ +            I       Y+VPF   LDLV+++KV L  G A++  ++I ++VL  FR+ LS+ L+     +  +  ++RL P+LS+L+  Y+G+DYS   N+ KI+ +QID LS KSFP CM++++ AL+ + H++H GRMQYGLFLKGIG+ LE++++FW+  F + K D++ F K YAY+IRH +G+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ +  A    I  I+  +K   +Q++C+ YF+L H + D    ++NHPN+YF ES+K+L
Sbjct:   23 LQFYGQPPLDNISLIEFETFAVERLKLLKTVENLGVSYVKTTDQYIKKLEAEFLSLNFPFRAEVDDRKVPGVTSEYEKRRKDHI-SHFILRLAYCQTEDLRRWFIQQEMDLFRYRFGI--LSSKHKTE-FLHKNNL-KYETVSAEEKKYLRDKLINSSYGLSGITLEEYDFYRVPFQDALDLVRTRKVYLLAGNAYIPQNEIVTIVLNDFRTRLSKALAVTARSLPAVQSDERLQPLLSHLSHAYVGQDYSIQKNVGKISLEQIDPLSGKSFPLCMRHLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQAMQFWRSEFVKGKVDADKFDKAYAYSIRHMFGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKIAPG-GINQILELVKGMHYQLACQKYFELTHSVEDA-GFSLNHPNQYFTESQKLL 460
[Close]
BLAST of DNA primase large subunit vs. Ensembl Zebrafish
Match: prim2 (DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-050522-471])

HSP 1 Score: 347.821 bits (891), Expect = 1.119e-113
Identity = 184/445 (41.35%), Postives = 280/445 (62.92%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKL-----STLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQ------------IDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PP D + L   E  A++RLK+L+ ++NL   YVK   +Y  ++ +    L     + +    V    S+  +   D I SH+ILR+AYC T++L +WFI QE+DLF+YRF    L++ H  + F+  N +   E + AE KK+ +            I       Y+VPF   LDLV+++KV L  G A++  ++I ++VL  FR+ LS+ L+     +  +  ++RL P+LS+L+  Y+G+DYS   N+ KI+ +QID LS KSFP CM++++ AL+ + H++H GRMQYGLFLKGIG+ LE++++FW+  F + K D++ F K YAY+IRH +G+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ +  A    I  I+  +K   +Q++C+ YF+L H + D    ++NHPN+YF ES+K+L
Sbjct:   23 LQFYGQPPLDNISLIEFETFAVERLKLLKTVENLGVSYVKTTDQYIKKLEAEFLSLNFPFRAEVDDRKVPGVTSEYEKRRKDHI-SHFILRLAYCQTEDLRRWFIQQEMDLFRYRFGI--LSSKHKTE-FLHKNNL-KYETVSAEEKKYLRDKLINSSYGLSGITLEEYDFYRVPFQDALDLVRTRKVYLLAGNAYIPQNEIVTIVLNDFRTRLSKALAVTARSLPAVQSDERLQPLLSHLSHAYVGQDYSIQKNVGKISLEQIDPLSGKSFPLCMRHLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQAMQFWRSEFVKGKVDADKFDKAYAYSIRHMFGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKIAPG-GINQILELVKGMHYQLACQKYFELTHSVEDA-GFSLNHPNQYFTESQKLL 460
[Close]
BLAST of DNA primase large subunit vs. Ensembl Zebrafish
Match: prim2 (DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-050522-471])

HSP 1 Score: 88.5817 bits (218), Expect = 8.690e-20
Identity = 56/160 (35.00%), Postives = 85/160 (53.12%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLS--------------TLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQ 506
            LQFY  PP D + L   E  A++RLK+L+ ++NL   YVK   +Y  ++ +    L+              T     V    S+  +   D I SH+ILR+AYC T++L +WFI QE+DLF+YRF    L++ H   +F+  N +   E + AE KK+ +
Sbjct:   23 LQFYGQPPLDNISLIEFETFAVERLKLLKTVENLGVSYVKTTDQYIKKLEAEFLSLNFPFRAEVYVHFFLITQDDRKVPGVTSEYEKRRKDHI-SHFILRLAYCQTEDLRRWFIQQEMDLFRYRFGI--LSSKHKT-EFLHKNNL-KYETVSAEEKKYLR 177
[Close]
BLAST of DNA primase large subunit vs. Ensembl Xenopus
Match: trpv2 (transient receptor potential cation channel, subfamily V, member 2 [Source:Xenbase;Acc:XB-GENE-6258127])

HSP 1 Score: 361.303 bits (926), Expect = 8.961e-119
Identity = 191/459 (41.61%), Postives = 289/459 (62.96%), Query Frame = 3 
Query:   48 KKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDI--------LSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGI-FVQEALPAEYKKFFQIDNTN------------IIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEE-KCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            KK+    LQFY  PPT+ + L   E  AI+RLK+L+ ++NL   Y+K   +Y+ ++   L KL    + F   AG      +ND++        +SH+ILR+AYC +++L +WFI QE+DLF++RF+   L     +++F+  N + +V  A+  E K   + D  N            +  YKVPF   LDLV+ +KV L  GFA++  +DI S+VL  FR+ LS+ L+     +  +  ++RL P+L++L+  Y+G+D+S+ +N  KI+ DQID  + KSFPPCM+ ++ +L+   H++H GRMQYGLFLKGIG+ LE++L+FWK  F + K DS  F K YAY+IRH+YG+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ F    S  I  I+  +K   +Q++C+ YF+L H + D+   ++ HPN+YF ES+K+L  +
Sbjct:    9 KKIQTTCLQFYQHPPTENISLTEFETFAIERLKLLKAVENLGVSYLKNSDDYNKKLEQELRKLKFPYRMFT--AGDRKCDEINDEVYDLRRKDHISHFILRLAYCQSEDLRRWFIQQEMDLFKFRFS---LLTKEKVQEFLKLNDLEYV--AISQEEKNMHKEDLMNSSFGLSLTKMEDLEFYKVPFQAALDLVRPRKVFLWHGFAYIPHTDIVSIVLNDFRTKLSKALALSARSLPVVQSDERLQPLLNHLSHSYIGQDFSTQSNTGKISLDQIDSHAAKSFPPCMRQLHKSLREHHHLRHGGRMQYGLFLKGIGLTLEQALQFWKLEFTKGKVDSEKFDKIYAYSIRHNYGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSF-KVPSSGINQILDLVKGMHYQLACQKYFELTHSV-DDCGFSLTHPNQYFAESQKLLTGS 458
[Close]
BLAST of DNA primase large subunit vs. Ensembl Xenopus
Match: trpv2 (transient receptor potential cation channel, subfamily V, member 2 [Source:Xenbase;Acc:XB-GENE-6258127])

HSP 1 Score: 358.992 bits (920), Expect = 8.348e-118
Identity = 185/444 (41.67%), Postives = 281/444 (63.29%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGI-FVQEALPAEYKKFFQIDNTN------------IIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEE-KCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            LQFY  PPT+ + L   E  AI+RLK+L+ ++NL   Y+K   +Y+ ++   L KL    +        ++      D +SH+ILR+AYC +++L +WFI QE+DLF++RF+   L     +++F+  N + +V  A+  E K   + D  N            +  YKVPF   LDLV+ +KV L  GFA++  +DI S+VL  FR+ LS+ L+     +  +  ++RL P+L++L+  Y+G+D+S+ +N  KI+ DQID  + KSFPPCM+ ++ +L+   H++H GRMQYGLFLKGIG+ LE++L+FWK  F + K DS  F K YAY+IRH+YG+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ F    S  I  I+  +K   +Q++C+ YF+L H + D+   ++ HPN+YF ES+K+L  +
Sbjct:   28 LQFYQHPPTENISLTEFETFAIERLKLLKAVENLGVSYLKNSDDYNKKLEQELRKLKFPYRALQDEINDEVYDLRRKDHISHFILRLAYCQSEDLRRWFIQQEMDLFKFRFS---LLTKEKVQEFLKLNDLEYV--AISQEEKNMHKEDLMNSSFGLSLTKMEDLEFYKVPFQAALDLVRPRKVFLWHGFAYIPHTDIVSIVLNDFRTKLSKALALSARSLPVVQSDERLQPLLNHLSHSYIGQDFSTQSNTGKISLDQIDSHAAKSFPPCMRQLHKSLREHHHLRHGGRMQYGLFLKGIGLTLEQALQFWKLEFTKGKVDSEKFDKIYAYSIRHNYGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSF-KVPSSGINQILDLVKGMHYQLACQKYFELTHSV-DDCGFSLTHPNQYFAESQKLLTGS 464
[Close]
BLAST of DNA primase large subunit vs. Ensembl Xenopus
Match: trpv2 (transient receptor potential cation channel, subfamily V, member 2 [Source:Xenbase;Acc:XB-GENE-6258127])

HSP 1 Score: 328.946 bits (842), Expect = 1.888e-106
Identity = 178/444 (40.09%), Postives = 268/444 (60.36%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGI-FVQEALPAEYKKFFQIDNTN------------IIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEE-KCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            LQFY  PPT+ + L   E  AI+RLK+L+ ++NL   Y+K   +Y+ ++   L KL      F      ++      D +SH+ILR+AYC +++L +WFI QE+DLF++RF+   L     +++F+  N + +V  A+  E K   + D  N            +  YKVPF   LDLV+ +KV L  GFA++  +DI S+VL  FR+ LS+ L+     +  +  ++RL P+L++L+  Y+G+D+S+ +N  KI+ DQID  + KSFPPCM+ ++ +L+   H++H GRMQYGLFLKGIG+ LE++L+FWK  F + K DS  F K YAY+IRH+YG+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ F   +S      I ++                    D+   ++ HPN+YF ES+K+L  +
Sbjct:   28 LQFYQHPPTENISLTEFETFAIERLKLLKAVENLGVSYLKNSDDYNKKLEQELRKLK-----FPYRINDEVYDLRRKDHISHFILRLAYCQSEDLRRWFIQQEMDLFKFRFS---LLTKEKVQEFLKLNDLEYV--AISQEEKNMHKEDLMNSSFGLSLTKMEDLEFYKVPFQAALDLVRPRKVFLWHGFAYIPHTDIVSIVLNDFRTKLSKALALSARSLPVVQSDERLQPLLNHLSHSYIGQDFSTQSNTGKISLDQIDSHAAKSFPPCMRQLHKSLREHHHLRHGGRMQYGLFLKGIGLTLEQALQFWKLEFTKGKVDSEKFDKIYAYSIRHNYGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSFKVPSSG-----INQV--------------------DDCGFSLTHPNQYFAESQKLLTGS 436
[Close]
BLAST of DNA primase large subunit vs. Ensembl Mouse
Match: Prim2 (DNA primase, p58 subunit [Source:MGI Symbol;Acc:MGI:97758])

HSP 1 Score: 362.073 bits (928), Expect = 3.201e-119
Identity = 183/440 (41.59%), Postives = 280/440 (63.64%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNT------------NIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PPT+ + L   ENLA DR+K+L+ I+NL   YVKG  +Y  ++ + + KL    K+       D  +    D +SH+ILR+AYC +++L +WFI QE+DL ++RF+   +     ++ F+ D+ +   EA+  E K   + D              +  +YKVPF   LDL + +KV L  GFA++   DI +++L  FR+ LS+ L+     +  +  ++RL P+L++L+  Y G+DYS+  N  KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F   K D + F K Y+YNIRHS+G+EGKR +Y P+SC+KII +NPP  GD HGCPF+HS+ EL+ Q ++ +    S  I  I+  +K   +Q++C+ YF++ H + D+   ++NHPN++F ES++IL
Sbjct:   26 LQFYLQPPTENISLTEFENLAFDRVKLLKAIENLGVSYVKGTEQYQSKLEAEIRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEDLRRWFIQQEMDLLRFRFS---ILPKDKVQSFLKDSHLHF-EAISDEEKTLREQDIMASSPSLSGIKLESESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQKNTGKISLDQIDSLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIRGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPGQGDYHGCPFRHSDAELLKQKMQSYKIPAS-GISQILDLVKGNHYQVACQKYFEMTHNV-DDCGFSLNHPNQFFFESQRIL 455
[Close]
BLAST of DNA primase large subunit vs. UniProt/SwissProt
Match: sp|P33610|PRI2_MOUSE (DNA primase large subunit OS=Mus musculus OX=10090 GN=Prim2 PE=1 SV=1)

HSP 1 Score: 362.073 bits (928), Expect = 2.239e-118
Identity = 183/440 (41.59%), Postives = 280/440 (63.64%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNT------------NIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PPT+ + L   ENLA DR+K+L+ I+NL   YVKG  +Y  ++ + + KL    K+       D  +    D +SH+ILR+AYC +++L +WFI QE+DL ++RF+   +     ++ F+ D+ +   EA+  E K   + D              +  +YKVPF   LDL + +KV L  GFA++   DI +++L  FR+ LS+ L+     +  +  ++RL P+L++L+  Y G+DYS+  N  KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F   K D + F K Y+YNIRHS+G+EGKR +Y P+SC+KII +NPP  GD HGCPF+HS+ EL+ Q ++ +    S  I  I+  +K   +Q++C+ YF++ H + D+   ++NHPN++F ES++IL
Sbjct:   26 LQFYLQPPTENISLTEFENLAFDRVKLLKAIENLGVSYVKGTEQYQSKLEAEIRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEDLRRWFIQQEMDLLRFRFS---ILPKDKVQSFLKDSHLHF-EAISDEEKTLREQDIMASSPSLSGIKLESESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQKNTGKISLDQIDSLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIRGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPGQGDYHGCPFRHSDAELLKQKMQSYKIPAS-GISQILDLVKGNHYQVACQKYFEMTHNV-DDCGFSLNHPNQFFFESQRIL 455
[Close]
BLAST of DNA primase large subunit vs. UniProt/SwissProt
Match: sp|P49643|PRI2_HUMAN (DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2)

HSP 1 Score: 360.533 bits (924), Expect = 1.109e-117
Identity = 187/443 (42.21%), Postives = 284/443 (64.11%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNII---------------IYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PP++ + L   ENLAIDR+K+L+ ++NL   YVKG  +Y  ++ S L KL    K+       D  +    D +SH+ILR+AYC ++EL +WFI QE+DL ++RF+   +     I+ F+ D+ +   EA+  E K    +    I+               IYK+PF   LDL + +KV L  GFA++   DI +++L  FR+ LS+ L+     +  +  ++RL P+L++L+  Y G+DYS+  N+ KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F + K D + F K Y+YNIRHS+G+EGKR +Y P+SC+KII SNPP  GD HGCPF+HS+ EL+ Q L+ +   +   I  I+  +K   +Q++C+ YF+++H + D+   ++NHPN++F ES++IL
Sbjct:   26 LQFYLQPPSENISLIEFENLAIDRVKLLKSVENLGVSYVKGTEQYQSKLESELRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEELRRWFIQQEMDLLRFRFS---ILPKDKIQDFLKDSQLQF-EAISDEEKT---LREQEIVASSPSLSGLKLGFESIYKIPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRAKLSKALALTARSLPAVQSDERLQPLLNHLSHSYTGQDYSTQGNVGKISLDQIDLLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCLKIILSNPPSQGDYHGCPFRHSDPELLKQKLQSY-KISPGGISQILDLVKGTHYQVACQKYFEMIHNV-DDCGFSLNHPNQFFCESQRIL 455
[Close]
BLAST of DNA primase large subunit vs. UniProt/SwissProt
Match: sp|O89044|PRI2_RAT (DNA primase large subunit OS=Rattus norvegicus OX=10116 GN=Prim2 PE=2 SV=1)

HSP 1 Score: 359.762 bits (922), Expect = 1.571e-117
Identity = 182/440 (41.36%), Postives = 280/440 (63.64%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNT------------NIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PPT+ + L   E+LA DR+K+L+ I+NL   YVKG  +Y  ++ + + KL    K+       D  +    D +SH+ILR+AYC +++L +WFI QE+DL ++RF+   +     ++ F+ D  +   EA+  E K   + D              +  +YKVPF   LDL + +KV L  GFA++   DI +++L  FR+ LS+ L+     +  +  ++RL P+LS+L+  Y G+DYS+  +  KI+ DQID LS KSFPPCM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FWK+ F + K D + F K Y+YNIRHS+G+EGKR +Y P+SC+KII +NPP  GD HGCPF+HS+ EL+ Q ++ +    S  I  I+  +K   +Q++C+ YF++ H + D+   ++NHPN++F ES++IL
Sbjct:   26 LQFYLQPPTENISLTEFESLAFDRVKLLKAIENLGVSYVKGTEQYQSKLEAEIRKL----KFSYRENLEDEYEPRRRDHISHFILRLAYCQSEDLRRWFIQQEMDLLRFRFS---ILPKDKVQSFLKDTHLHF-EAISDEEKTLREQDIMASSPSLSGVRWESESVYKVPFADALDLFRGRKVYLEDGFAYVPLKDIVAIILNEFRATLSKALALTARSLPAVQSDERLQPLLSHLSHSYTGQDYSTQKSTGKISLDQIDSLSTKSFPPCMRQLHKALRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWKQEFIKGKMDPDKFDKGYSYNIRHSFGKEGKRTDYTPFSCMKIILTNPPSQGDFHGCPFRHSDAELLKQKMQTYKIPAS-GISQILDLVKGNHYQVACQKYFEMTHNV-DDCGFSLNHPNQFFFESQRIL 455
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BLAST of DNA primase large subunit vs. UniProt/SwissProt
Match: sp|Q84WJ2|PRI2_ARATH (Probable DNA primase large subunit OS=Arabidopsis thaliana OX=3702 GN=At1g67320 PE=2 SV=2)

HSP 1 Score: 303.138 bits (775), Expect = 3.337e-96
Identity = 178/443 (40.18%), Postives = 263/443 (59.37%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCI-DNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSI--------KKFMFDNGIFVQEALPAEYKKFFQID-NTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQEL----SYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQN 1355
            L  Y   P   V L+  E  AIDRL+VL+ + D L+    +   E  D V        TL K  +    S++S+ +N DI+SH++LR+ YC +DEL KWF++ E  LF++RF  +++    +I        K  +      ++E L    +   QI  +   I YKVPF +V DLV S++V L KGFAF+  + + SLV+  FRS+LS+ L          I E  E+DRL PI+  L+  YLG DYS +N    I+   ID +S  SFP CM+++   L+ D H+KH GRMQ GLFLKG+G+ L+++L FW++ F +K  S  F K+YAY IRH+YG+EGKR +Y PY+C KIITS  P AGD HGCP++H + + +   L +    +S  +E ++ K++ + +Q++C   F+ V+G   +    INHPN+YFEES+KIL++
Sbjct:   21 LPLYLTAPHMEVRLEEFELFAIDRLRVLKGVSDGLAR--ARNPNEMDDLV-------ETLWKEHMRL--SNVSEMINKDIISHFVLRLVYCRSDELKKWFLSMETALFRHRFRLKKIEEQRAIVGEFGLPYKAVIGAELESLKERLGLVARSHGQISSDVENIYYKVPFEEVPDLVASRRVLLQKGFAFVAGTQLVSLVVTQFRSHLSKALILTNRKWTTTIRE-REKDRLTPIVEALSTSYLGPDYSQSNEYADISLKDIDQVSKSSFPLCMRHLFEKLREDHHLKHGGRMQLGLFLKGVGLKLDDALAFWREEFTKKVGSERFDKEYAYAIRHNYGKEGKRTDYTPYACSKIITS-APGAGDHHGCPYRHFSEDNLKAALSRMG-LSSRGMEDVMDKVRNRHYQLACTLTFEAVYGTSCD--TGINHPNQYFEESQKILKS 447
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BLAST of DNA primase large subunit vs. UniProt/SwissProt
Match: sp|Q9VPH2|PRI2_DROME (DNA primase large subunit OS=Drosophila melanogaster OX=7227 GN=DNApol-alpha60 PE=1 SV=2)

HSP 1 Score: 264.618 bits (675), Expect = 2.243e-80
Identity = 164/457 (35.89%), Postives = 256/457 (56.02%), Query Frame = 3 
Query:   39 SLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYF--VSNAGS-----DISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQ---EALPAEYKKFFQIDNTN--------IIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQN 1355
            SL  K   N +  Y+ PPT+ V +D  E LA++RL++LR +D  S   ++   +   ++ S       L  Y    S  GS     DI Q+   D LSH+ILR+AYC +++L++WF+A+E++LF+Y+F A    +   +K+F+  NG  +    EA   E K                 +  YKVPF QVLDLV+ ++  L  G+A++   D+ SLV    +  + Q L   +  + +++ ++R+   L  L+  Y G+DY+   +   +  + +D LS  S P CM+  +  ++ + H+KH GRMQYGLFLKGIGV LE+SL+FW++ F +K D++ F + Y YNI H+YG++G  VNY PYSC KII  +    GDCHGCP+++ +   +   L  +  + S  I+ ++  +    +QI C  YF+L H  P     +INHPN YFEES+  + N
Sbjct:   19 SLETKYPHN-VMLYHYPPTEDVHIDEFEELALERLRLLRVLDRASTRNLRVLSDEWKEIVSADLTREGLRSYLRLCSTGGSAKHEADI-QTRRRDYLSHFILRLAYCRSEDLARWFVAREMELFRYKFAA---LSSFEVKQFLEANGFEIHPLTEAQKDEVKDGLYESTVGQSVAKIELLDFYKVPFTQVLDLVRGRRCFLKAGYAYVNTHDLVSLVGTKQQDEIEQGLQAAKTMVEDVEADERISRTLKALHNSYTGRDYTVCRDA-AVPIESLDQLSKTSMPLCMRMCHEHIRANHHIKHSGRMQYGLFLKGIGVALEDSLRFWREEFTKKMDADKFTRSYEYNIYHNYGKKGSMVNYTPYSCAKII-KDVAGPGDCHGCPYKNMDQGSLKTKLSSYGLSAS-AIDEVMFFVSRGHYQIGCGKYFQLTHNSP--VEPSINHPNNYFEESQIAMGN 465
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BLAST of DNA primase large subunit vs. TrEMBL
Match: A0A183AJT3 (DNA primase large subunit OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS7218 PE=3 SV=1)

HSP 1 Score: 407.912 bits (1047), Expect = 1.554e-133
Identity = 205/466 (43.99%), Postives = 301/466 (64.59%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGS--DISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERL---ANPHSIKKFMFDNGIFVQEALPAEYKKFFQ----------IDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHE--IDEEDRLMPILSNLNKRYLGKDYSS-ANNMDKITADQIDGLSVKS--FPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNY--PITINHPNEYFEESRKILQN 1355
            ME+K S S K    RLQFY  PP++T+ L+ LE  A+DR++ L+C++ + +D+V G  EY + + S L+KL   GK       S  +  + +  DI+SH++L++AYC +++L +WFI QE++LF+YRF  ER    A P  I  F+ +N +     L +E  +             +D      YKV F +V +LV++++V +  G+A++ D D+ SLV+ HFR+ LS  L+ L L +      EE+R++P+L++L+ RYLG+DYS+ A  M  I A+QID L+ +   FPPCM  ++ ALK   H++H GRMQYGLFLKGIGVPLEESLKFW+  F  K DS+ FAK YAYNIRH+YG+EGKR +Y PYSCVKII+S  P  GD HGCPF+H + +L+ Q L      TS+ +++I+ + K + + +SCR YF+ +H L       ITI+HPN+YFEES+++L+ 
Sbjct:    1 MEFKVSHSVKRGPTRLQFYRNPPSETIELNELEQYAVDRIRALKCVETVRQDFVFGSHEYEEHLTSELTKLGPFGKSLTITTASSKNAKEDIRRDIISHFVLQVAYCRSEDLRRWFIQQEVELFRYRFIRERNSSNAGPDVIASFLDENQLHFTHLLDSERNRILHYLAAGTAASGLDLQTTAFYKVYFAEVPELVRTRRVYVSGGYAYVPDPDLVSLVVSHFRTSLSCNLARLGLTLTSKLASEENRVLPLLASLSSRYLGEDYSAKAPTMGIIKAEQIDSLAKQPGVFPPCMAQLHEALKTQHHLRHAGRMQYGLFLKGIGVPLEESLKFWRNSFAPKYDSDQFAKNYAYNIRHNYGKEGKRTDYTPYSCVKIISSTAPGPGDYHGCPFRHMDPDLLRQRLSSSGRLTSDSVDTIVQRAKERLYHLSCREYFRAMHKLDAEAMSGITIHHPNQYFEESQRVLRG 466
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BLAST of DNA primase large subunit vs. TrEMBL
Match: A0A4Z2CMN7 (DNA primase large subunit OS=Schistosoma japonicum OX=6182 GN=EWB00_009184 PE=3 SV=1)

HSP 1 Score: 402.134 bits (1032), Expect = 2.470e-131
Identity = 205/468 (43.80%), Postives = 305/468 (65.17%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGS--DISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAER---LANPHSIKKFMFDNG-----------IFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHE--IDEEDRLMPILSNLNKRYLGKDYSS-ANNMDKITADQIDGLSVKS--FPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFK--LVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            ME+K     K    RLQFY+ PP+ T+ L  LE+ A+ R++VL+C++ + +D ++G  +Y D++ + L K+   GK F S + S  +  + ++ DI+SH+IL++AYC +++L +WF+ QE+DLF++RF  ER   ++ P  I +F+ +N            I +Q  L A       +D+     YKV F +V DLV+S++V +  G+AF+ + D+ SLV+  FR+ LS+ LS+L L +      EE+R++P+LS L+ RYLG+DYS+ A     I AD IDG + +   FPPCM  ++ ALK   H++H GRMQYGLFLKGIG+PLEESLKFW+K F  KCD++ F K YAYNIRH+YG+EGKR +Y PYSC+KII+ + P AGD HGCPF+H + EL+ Q L      +SE  E+I+ + K + + +SCR Y +  L   + D   +TI+HPN+YFEE+RK+ Q+N
Sbjct:    1 MEFKSPAVSKHKLIRLQFYSCPPSQTIELSELEDYAVHRIRVLKCVETVGQDCIRGTKDYDDKIIAELGKIGGFGKIFTSCSSSLKNAKEDIHKDIISHFILQVAYCRSEDLRRWFVQQEVDLFRFRFLNERNNSVSGPEIISRFLHENHLNFTPISDTERINLQRYLVAGTATT-GVDHNTTAFYKVHFTKVPDLVRSRRVFVQGGYAFVPEPDLVSLVVSCFRTSLSRNLSHLGLTLCSRIACEENRILPLLSTLSNRYLGEDYSAKAPVTGAIKADDIDGFAKQPGLFPPCMAQLHEALKAHHHLRHAGRMQYGLFLKGIGLPLEESLKFWRKAFSPKCDNDQFNKAYAYNIRHNYGKEGKRADYTPYSCIKIISGSAPGAGDYHGCPFRHMDPELLQQRLLSGGRLSSEVAETIVQRAKERLYHLSCREYLRGMLKLSVDDISGVTIHHPNQYFEEARKLSQSN 467
[Close]
BLAST of DNA primase large subunit vs. TrEMBL
Match: C4QIH8 (DNA primase large subunit, putative OS=Schistosoma mansoni OX=6183 GN=Smp_079050.1 PE=4 SV=1)

HSP 1 Score: 401.364 bits (1030), Expect = 4.286e-131
Identity = 200/467 (42.83%), Postives = 306/467 (65.52%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGS--DISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAER---LANPHSIKKFMFDNGIFVQEALPAEYKKFFQ----------IDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHI--HEIDEEDRLMPILSNLNKRYLGKDYS-SANNMDKITADQIDGLSVKS--FPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFK--LVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            ME+K     K    RLQFYN PP+D + L+ LE+ A+ R++VL+C++ + +DY++G  +Y D++ + L+K+S  GK F S + S  +  + ++ DI+SH+IL++AYC +++L +WF+ QE+DLF++RF  ER         I +F+++N +       +E                ID+     YKV F +V DL++S++V +  G+AF+ + D+ SLV+  FR+ LS+ L++L L +    + EE+R++P+LS+L+ RYLG+DYS  A     + AD I+G S +   FPPCM  ++ ALK   H++H GRMQYGLFLKGIG+PLEESLKFW+K F  KCD++ F K YAYNIRH+YG+EGKR +Y PYSC++I++ + P AGD HGCPF+H + EL+ Q L      + + +E+I+ + K + + +SCR Y +  L   + D   +TI+HPN+YFEE+RKILQ N
Sbjct:    1 MEFKSPAVAKHKLIRLQFYNCPPSDIIELNELEDYAVHRIRVLKCVEAVGQDYIRGTKDYDDKMITELTKISGFGKIFTSPSSSLKNAKEDIHKDIVSHFILQVAYCRSEDLRRWFVQQEVDLFRFRFLNERNNSTFGSEVISRFLYENHLHFTLMSDSERTNLLNYLIAGTATVGIDHNTTAFYKVHFTEVPDLIRSRRVFVQGGYAFVPEPDLVSLVVSCFRTSLSRNLAHLGLTLCSRTVCEENRVLPLLSSLSNRYLGEDYSIKAPVTGLVKADDIEGFSRQPGLFPPCMAQLHEALKVHHHLRHSGRMQYGLFLKGIGLPLEESLKFWRKVFSPKCDNDQFHKAYAYNIRHNYGKEGKRADYTPYSCIRIVSGSAPGAGDYHGCPFRHMDPELLRQRLLSGGRLSLDVVETIVLRAKERLYHLSCREYLRGMLKLSVDDISGVTIHHPNQYFEEARKILQGN 467
[Close]
BLAST of DNA primase large subunit vs. TrEMBL
Match: A0A5J4N7U6 (DNA primase large subunit OS=Paragonimus westermani OX=34504 GN=DEA37_0011179 PE=3 SV=1)

HSP 1 Score: 400.593 bits (1028), Expect = 8.403e-131
Identity = 208/471 (44.16%), Postives = 299/471 (63.48%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGK------YFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHS---IKKFMFDNGIFVQEALPAEYKKFFQ----------IDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHE--IDEEDRLMPILSNLNKRYLGKDYSS-ANNMDKITADQIDGLSVKS--FPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNY--PITINHPNEYFEESRKILQNN 1358
            ME+K + +      RLQFY  PP++T+ L+ LE  AIDR+++L+C++ + +D+  G  EY +++ S L KL   GK       F  NA  DI +    DI+SH+IL++AYC  ++L +WFI QE+DLF+YRF  ER  +P     I  F+  N ++      AE  +  Q          ID      YKV F +V +LV+S+++ +  GFA++ D+D+ SLV+ HFR+ LS  L+ L L +      EE R++P+L++L+ RYLG+DYSS A  +D I A+Q+D L+ +   FPPCM  ++ ALK   H++H GRMQYGLFLKGIG+PLEESLKFW+  F  K DS  FAK YAYNIRH+YG+EGKR +Y PYSCVKII+S  P AGD HGCPF+H + EL+ Q L       S+ +++I+ + K + + + CR YF+ +H L  +    +TI HPN+YFE S+K+L+  
Sbjct:    1 MEFKATTTHNRGPIRLQFYRDPPSETIELNELEQFAIDRMRILKCVEAVRQDFKVGSSEYEERLTSELIKLGPFGKSLTTPTIFSKNATEDIRR----DIISHFILQVAYCRGEDLRRWFINQEVDLFRYRFLLERNVSPFGPDVISDFLTQNRLYFSHLSDAERSQIRQQLIAGTAAPGIDFQTTAFYKVYFTEVPELVRSRRIFIRAGFAYVPDTDLVSLVVSHFRTSLSCNLARLGLTLGSRMASEEFRVLPLLASLSSRYLGEDYSSKAQAVDSIKAEQVDVLARQPGVFPPCMSQLHEALKAQHHLRHAGRMQYGLFLKGIGLPLEESLKFWRSAFAPKYDSEQFAKSYAYNIRHNYGKEGKRADYTPYSCVKIISSTAPGAGDYHGCPFRHMDPELLRQRLSSSGRIPSDIVDNIVQRAKERLYHLCCREYFRALHKLDVDAMSGVTITHPNQYFELSQKVLRGE 467
[Close]
BLAST of DNA primase large subunit vs. TrEMBL
Match: A0A0R3S9S1 (DNA primase large subunit OS=Hymenolepis diminuta OX=6216 GN=HDID_LOCUS1019 PE=3 SV=1)

HSP 1 Score: 400.593 bits (1028), Expect = 2.235e-130
Identity = 200/465 (43.01%), Postives = 306/465 (65.81%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFV--SNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHS---IKKFMFDNGIFVQEALPAEYKKFFQ--IDNTNII--------IYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHI--HEIDEEDRLMPILSNLNKRYLGKDYSSANN--MDKITADQIDGLSVKS--FPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVH---GLPDNYPITINHPNEYFEESRKI 1346
            M++ + +S K    R+QFYN PPT T+ L+ LE LAI+RLK+L+CI+ + +D+++G  EY +++ + L K+  +GK F   SN   +I++ +++D+ SH+IL++AYC ++ + +WFI QE+DLF+YRFN ER A+ HS   I +F+  N +        E  +  +  +  TNI          YKV F +V DLV+ ++V L  GFA++ D+++ SLV+  FR+ LS+ LS L L +     DE  RL+P+L+ L+KRYLG D  S        +++ Q+  L+     FPPCM  ++ AL  + H++HWGRMQYGLFLKGIG+ L+E+LKFW+  F  K D++ FAK+YAY+IRH+YG+EGKR +Y PYSC+KII+ N P  G+ HGCPF+H ++EL+ Q L       S+Q+E+I+ + K KQ+Q++CR +FK +H    + D   I INHPN+Y+E ++K+
Sbjct:   16 MDFAKPISSKNQTPRIQFYNEPPTHTLGLEHLEQLAIERLKILKCIETVGQDFIRGSKEYDERLSAELCKIGPIGKSFTLTSNQPKNITEDIHNDVTSHFILQIAYCRSETMRRWFIQQEVDLFRYRFNLERAASGHSMDTINEFLRINNLHFTSIGSDESSRLREQLVSGTNIYGVSGDYANFYKVHFTEVPDLVRRRQVFLKAGFAYVPDAELVSLVVTRFRASLSRNLSRLGLALVPRLADEGARLLPLLTGLSKRYLGDDDFSTKKPIFGAVSSGQVADLARTPGLFPPCMSRLHEALAANHHLRHWGRMQYGLFLKGIGLSLDEALKFWRNSFAPKVDTDQFAKQYAYSIRHNYGKEGKRADYTPYSCMKIISFNQPATGEFHGCPFRHLDLELLHQRLSVGGKVPSDQVEAIVKRSKDKQYQLACREFFKAMHPDLSVEDASTIVINHPNQYYELAQKV 480
[Close]
BLAST of DNA primase large subunit vs. Ensembl Cavefish
Match: prim2 (DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-050522-471])

HSP 1 Score: 306.99 bits (785), Expect = 3.026e-98
Identity = 167/430 (38.84%), Postives = 264/430 (61.40%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFL--LDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQ Y  PP + + L   E  A++RLK+L+ ++NL   YVK   +Y+ ++++ +S L+   K  V   G    +    D +SH+ILR+AYC T++L +WFI QE+DLF++RFN   L++ +  + F+  N +   + L A+ K   +    + +I        + +V+    K+   F F     S   SL  W     +  +LS     +  +  ++RL P+L++L+  Y+G+DYS   N+ KI+ +QID LS KSFP CM+ ++ +L+ + H++H GRMQYGLFLKGIG+ LE++L+FW+  F   K D++ F K YAY+IRH +G+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ +  + S  I  I+  +K   +Q++C+ YF+L H + D    ++NHPN+YF ES+++L
Sbjct:   23 LQLYVQPPLENISLSEFETFAVERLKLLKTVENLGVSYVKTTEQYTKKLHAEISNLNFPHKAEV--VGPSEYEKRRKDHISHFILRLAYCQTEDLRRWFIQQEMDLFRHRFND--LSSKYKTE-FLHKNNL-KYDTLSADEKMTLK----DQLINSTFGFSGITIVEQDFYKVRPKFRFFPSYTSAYPSLETW---KVVFNKLSLTARSLPAVQSDERLQPLLNHLSHAYVGQDYSIQKNIGKISLEQIDPLSAKSFPLCMRQLHKSLRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWRSEFIRGKVDADKFDKAYAYSIRHMFGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKLSPS-GIVQILELVKGMHYQLACQKYFELTHNIEDA-GFSLNHPNQYFMESQRLL 437
[Close]
BLAST of DNA primase large subunit vs. Ensembl Cavefish
Match: prim2 (DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-050522-471])

HSP 1 Score: 303.138 bits (775), Expect = 9.734e-97
Identity = 166/437 (37.99%), Postives = 265/437 (60.64%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLS----TLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFF--QIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYL---SQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQ Y  PP + + L   E  A++RLK+L+ ++NL   YVK   +Y+ ++++ +S L+        +  S  G    +    D +SH+ILR+AYC T++L +WFI QE+DLF++RFN   L++ +  + F+  N +   + L A+ K     Q+ N+      +  ++  D  K           F+ +     ++++ F   +    Q L+   L   + DE  RL P+L++L+  Y+G+DYS   N+ KI+ +QID LS KSFP CM+ ++ +L+ + H++H GRMQYGLFLKGIG+ LE++L+FW+  F   K D++ F K YAY+IRH +G+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L+ +  + S  I  I+  +K   +Q++C+ YF+L H + D    ++NHPN+YF ES+++L
Sbjct:   23 LQLYVQPPLENISLSEFETFAVERLKLLKTVENLGVSYVKTTEQYTKKLHAEISNLNFPHKAEASFTKSQVGPSEYEKRRKDHISHFILRLAYCQTEDLRRWFIQQEMDLFRHRFND--LSSKYKTE-FLHKNNL-KYDTLSADEKMTLKDQLINSTFGFSGITIVEQ-DFYKK----------FIFNYSCLCIMIYLFNGLMIMPHQSLTARSLPAVQSDE--RLQPLLNHLSHAYVGQDYSIQKNIGKISLEQIDPLSAKSFPLCMRQLHKSLRENHHLRHGGRMQYGLFLKGIGLTLEQALQFWRSEFIRGKVDADKFDKAYAYSIRHMFGKEGKRTDYTPYSCMKVILSNPPSQGDYHGCPFRHSDPELLKQKLQSYKLSPS-GIVQILELVKGMHYQLACQKYFELTHNIEDA-GFSLNHPNQYFMESQRLL 440
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BLAST of DNA primase large subunit vs. Ensembl Sea Lamprey
Match: prim2 (DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-050522-471])

HSP 1 Score: 328.946 bits (842), Expect = 7.015e-108
Identity = 168/442 (38.01%), Postives = 265/442 (59.95%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLK-VLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKF--------FQIDNTNI---IIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            LQ Y  PP  +V L   E LA+ RL  VL+ ++ +   ++KG   Y  ++   L K     +  ++    D  +    D +SH+ILR+AYC +++L +WFI QE+DLF++RF  +      S+  F+  N +  +     E K+         + + +  +     YKVPF   L+LV+S+KV + +G AF+   D+ ++VL  FR  LS+ L+     +  + E++RL P+L++L+K Y+G+DYS+  +  +I+ DQ+D  + +SFP CM+ V+SAL+   H++H GRMQYGL+LKGIG+ L++SL+FW+  F     ++ F K YAYN+RH+YG+EGKR +Y PYSC+KII +N P  GD HGCPF+H+  EL+   L  +    S  I  I+  +K   +Q++C+ YF++ H + D     +NHPNEYFEES ++L   
Sbjct:    5 LQLYVRPPLGSVSLVEFEALAVQRLAAVLKSVERIGVLFMKGTENYDKKLEEELKKSKFPYRDNITLIEVDDQEPRKRDHISHFILRLAYCQSEDLRRWFIQQEMDLFRFRFLQQ---TSESVTSFLNQNNLTYESLSKEEIKEHELKLIASSYGMSHHKVNESTFYKVPFTDALELVRSRKVFVRRGMAFIPQRDLVTIVLNDFRQNLSRALTITARLLPSVQEDERLQPLLTHLSKSYIGQDYSAPKHAGQISLDQLDSHAARSFPLCMRQVHSALREHHHLRHGGRMQYGLYLKGIGLTLQQSLEFWRAEFALGVGADKFDKSYAYNVRHNYGKEGKRTDYTPYSCMKIIMTNMPAQGDYHGCPFRHTEPELLKMKLLAY-KVPSADISQILDLVKGMHYQLACQKYFEVTHKVEDT-SFALNHPNEYFEESMRLLSGG 441
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BLAST of DNA primase large subunit vs. Ensembl Yeast
Match: PRI2 (Subunit of DNA primase; DNA primase is required for DNA synthesis and double-strand break repair [Source:SGD;Acc:S000001528])

HSP 1 Score: 211.075 bits (536), Expect = 4.309e-62
Identity = 152/478 (31.80%), Postives = 242/478 (50.63%), Query Frame = 3 
Query:   42 LSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDN-LSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMND---DILSHYILRMAYCFTDELSKWFIAQELDLFQYRFN------------------------AERLANPHSIKKFMFDNGIFVQEALPAEY--KKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSS--ANNMDKITADQIDGLSVKS------FPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNT--FAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHG-----LPDNYPITINHPNEYFEESR 1340
            L  +L  ++L FY++PP   + L+  E  AIDRLK+L  I++ LS +  K   E    +  +  KL               ++S+ D   D  SH+ILR+ +C + EL + F+  E  LF+ RFN                         E+    H + + +  +  F Q  L  E+  K++FQ +       K+PF  V++LV ++ V L  G+A+L      +L+   F S L+QEL     ++  ++E+DRL+PIL++L+  Y   D++   AN   +   D+I+  SV S      +P C++N+   LK++ H++++GR Q  LFLKGIG+  +E+LKFW + F    +     F K+Y Y+ RH+YG EG R+NY P+ C  I++   P  GD HGCPF+  + E ++  LR     T  QI S++   +  ++ I+C   F++ H      L       I HPN YFE SR
Sbjct:   50 LYARLYESKLSFYDLPPQGEITLEQFEIWAIDRLKILLEIESCLSRN--KSIKEIETIIKPQFQKLLPFN-----------TESLEDRKKDYYSHFILRLCFCRSKELREKFVRAETFLFKIRFNMLTSTDQTKFVQSLDLPLLQFISNEEKAELSHQLYQTVSASLQF-QLNLNEEHQRKQYFQQEK----FIKLPFENVIELVGNRLVFLKDGYAYLPQFQQLNLLSNEFASKLNQELIKTYQYLPRLNEDDRLLPILNHLSSGYTIADFNQQKANQFSENVDDEINAQSVWSEEISSNYPLCIKNLMEGLKKNHHLRYYGRQQLSLFLKGIGLSADEALKFWSEAFTRNGNMTMEKFNKEYRYSFRHNYGLEGNRINYKPWDCHTILSKPRPGRGDYHGCPFRDWSHERLSAELRSMK-LTQAQIISVLDSCQKGEYTIACTKVFEMTHNSASADLEIGEQTHIAHPNLYFERSR 508
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BLAST of DNA primase large subunit vs. Ensembl Nematostella
Match: EDO47437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM38])

HSP 1 Score: 345.125 bits (884), Expect = 4.892e-113
Identity = 183/446 (41.03%), Postives = 275/446 (61.66%), Query Frame = 3 
Query:   63 NRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMND------DILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQ--------IDNTNIII---YKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNM--DKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRK 1343
            +RLQ Y IPPTD + L+  E LAI+RLKVLR ++ L   + +   EY +++   LS    L   ++SN  S  S + ++      D +SH+ILR+AYC +++L +WF+ QE +LF++RF  E       +++F+  N +        E   F +        + +  ++    YKV F + LDLV+S+KV L +G A++    + S++   FR+ LS  L+     +  ++E+DRL+P LSNL+++YLG+DYS   N+   KIT DQID +S KSFP CM+ ++  L+ + H+KH GRMQYGLFLKGIG+ LEESL FW+  F    D + F K+YAYNIRH+YG+EGKR +Y PYSC+KII SN P  GDCHGC ++H++ +L+ Q L +      E ++ I+  +K   +Q++C  +F++ H +        NHPN+YFEESRK
Sbjct:   28 DRLQMYKIPPTDNISLEEFEELAIERLKVLREVETLGIRFKRESKEYKEKMSKHLSDF--LPHLYISNMYSSKSTANDEYDDKRKDHISHFILRLAYCRSEDLRRWFLLQESELFRFRFVTEEEGK--GVEEFLQHNSLSYTPIGEEEKTTFLEKLRDSGYNLTDAAVLASKYYKVHFTEALDLVRSRKVFLREGSAYIPHQSLVSIITNVFRTQLSHALAVTARALPYLEEDDRLLPRLSNLSRQYLGQDYSQKKNIAGGKITLDQIDAVSQKSFPLCMRQLHQNLRENHHLKHGGRMQYGLFLKGIGLTLEESLAFWRTEFIRIMDLDKFDKQYAYNIRHNYGKEGKRADYTPYSCMKIIMSNQPGPGDCHGCTYRHTDPDLLRQQLARH-KLGKEGLDEIMKLVKETHYQLACTRFFEVTHNVSG--LSAFNHPNQYFEESRK 466
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BLAST of DNA primase large subunit vs. Ensembl Nematostella
Match: EDO47436 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RM37])

HSP 1 Score: 88.5817 bits (218), Expect = 2.998e-19
Identity = 85/351 (24.22%), Postives = 149/351 (42.45%), Query Frame = 3 
Query:  147 VLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMND------DILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKF--------FQIDNTNIII---YKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSF----PPCMQNVNSALKRDSHVKHWGR-----MQYGLFLK------------------GIGVPLEESLKFWKKGFEEK--CDSNTFAKKYAYNIRHSYGQEGKRVN 1061
            V R ++ L   + +   EY +++   LS    L   ++SN  S  S + ++      D +SH+ILR+AYC +++L +WF+ QE +LF++RF  E       +++F+  N +        E   F        + + +  ++    YKV F + LDLV+S+KV L +G A++    + S++   FR+ LS  L+   + +         +P              +       I     +    K F    PP   + +   +R+  +K W       +  G +                    G G+P +    F+   +  K       F K+YAYNIRH+YG+EGKR +
Sbjct:    3 VXREVETLGIRFKRESKEYKEKMSKHLSDF--LPHLYISNMYSSKSTANDEYDDKRKDHISHFILRLAYCRSEDLRRWFLLQESELFRFRFVTEEEGK--GVEEFLQHNSLSYTPIGEEEKTTFLEKLRDSGYNLTDAAVLASKYYKVHFTEALDLVRSRKVFLREGSAYIPHQSLVSIITNVFRTQLSHALAVSIIVL--------CLP---------FNGPSTDQGGFHAIIETPCNHGEDKGFPEILPPVYASASPEFEREPSLKAWWSYAIWTLSQGYWFNPGGVSGILENRVHKDNGLGQGLPRQPFNPFYSSDYHYKRIIQYFQFDKQYAYNIRHNYGKEGKRAD 332
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BLAST of DNA primase large subunit vs. Ensembl Medaka
Match: prim2 (DNA primase subunit 2 [Source:NCBI gene;Acc:101155378])

HSP 1 Score: 345.125 bits (884), Expect = 5.131e-113
Identity = 182/439 (41.46%), Postives = 268/439 (61.05%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKF--------FQIDNTNII---IYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL 1349
            LQFY  PP + + L   E  A++RLK+L+ ++NL   YVK   +Y  ++ + L  L     +F     +        D +SH+ILR+AYC T++L +WFI QE+DLF+YRF       P    +F+  N +        E  +         + +    +     YKVPF   LDLV+S+KV L  GFAF+   DI ++VL  FR+ LS+ L+     +  +  ++RL P+L++L+  YLG+DYS   N+ KI+ +QID LS KSFP CM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FW+  F   K D++ F K YAY IRH YG+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L +F   +   I  I+  +K   FQ++C+ YF++ H + D+   +++HPN+YF ES+K L
Sbjct:   23 LQFYGEPPLENISLAEFETFAVERLKLLKTVENLGVSYVKHSSQYKLKMDNELRLL-----HFPYRPDT----KRRKDHISHFILRLAYCQTEDLRRWFIQQEVDLFRYRFTD---LPPQQKLEFLHKNNLKYNTLSDKEKNELSDKLLMSSYSVSGVTVEKLEFYKVPFQDALDLVRSRKVYLKAGFAFVPQQDIVTIVLNDFRTRLSKALALTARSLPAVHSDERLHPLLNHLSHAYLGQDYSIQKNVGKISLEQIDSLSGKSFPLCMRQLHQALRENHHLRHGGRMQYGLFLKGIGISLEQALQFWRSEFIRGKVDADKFDKAYAYGIRHMYGKEGKRADYTPYSCMKVILSNPPSQGDHHGCPFRHSDPELLKQKL-QFYKVSPSSITQIMELVKGMHFQLACQKYFEVTHNVEDS-SFSLSHPNQYFIESQKAL 447
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BLAST of DNA primase large subunit vs. Ensembl Medaka
Match: prim2 (DNA primase subunit 2 [Source:NCBI gene;Acc:101155378])

HSP 1 Score: 326.635 bits (836), Expect = 7.296e-106
Identity = 172/418 (41.15%), Postives = 252/418 (60.29%), Query Frame = 3 
Query:   69 LQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSN-AGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKF--------FQIDNTNII---IYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGF-EEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGL 1283
            LQFY  PP + + L   E  A++RLK+L+ ++NL   YVK   +Y  ++ + L  L    +       G    +    D +SH+ILR+AYC T++L +WFI QE+DLF+YRF       P    +F+  N +        E  +         + +    +     YKVPF   LDLV+S+KV L  GFAF+   DI ++VL  FR+ LS+ L+     +  +  ++RL P+L++L+  YLG+DYS   N+ KI+ +QID LS KSFP CM+ ++ AL+ + H++H GRMQYGLFLKGIG+ LE++L+FW+  F   K D++ F K YAY IRH YG+EGKR +Y PYSC+K+I SNPP  GD HGCPF+HS+ EL+ Q L +F   +   I  I+  +K   FQ++C+ YF++ H +
Sbjct:   23 LQFYGEPPLENISLAEFETFAVERLKLLKTVENLGVSYVKHSSQYKLKMDNELRLLHFPYRPDTKPLTGPSEFEKRRKDHISHFILRLAYCQTEDLRRWFIQQEVDLFRYRFTD---LPPQQKLEFLHKNNLKYNTLSDKEKNELSDKLLMSSYSVSGVTVEKLEFYKVPFQDALDLVRSRKVYLKAGFAFVPQQDIVTIVLNDFRTRLSKALALTARSLPAVHSDERLHPLLNHLSHAYLGQDYSIQKNVGKISLEQIDSLSGKSFPLCMRQLHQALRENHHLRHGGRMQYGLFLKGIGISLEQALQFWRSEFIRGKVDADKFDKAYAYGIRHMYGKEGKRADYTPYSCMKVILSNPPSQGDHHGCPFRHSDPELLKQKL-QFYKVSPSSITQIMELVKGMHFQLACQKYFEVTHNV 436
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BLAST of DNA primase large subunit vs. Planmine SMEST
Match: SMESG000059945.1 (SMESG000059945.1)

HSP 1 Score: 915.22 bits (2364), Expect = 0.000e+0
Identity = 439/445 (98.65%), Postives = 441/445 (99.10%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDIS+ MNDDILSHYILRMAYCFTDELSKWFI QELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTN IIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESII KIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL+NN
Sbjct:    1 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISRLMNDDILSHYILRMAYCFTDELSKWFITQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNTIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIIAKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILKNN 445
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BLAST of DNA primase large subunit vs. Planmine SMEST
Match: SMESG000059950.1 (SMESG000059950.1)

HSP 1 Score: 910.598 bits (2352), Expect = 0.000e+0
Identity = 437/445 (98.20%), Postives = 440/445 (98.88%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN 1358
            MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDIS+SMNDDILSHYILRMAYCFTDELSKWFIA+ELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTN IIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFP CMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSC KIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESII KIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKI +NN
Sbjct:    1 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISRSMNDDILSHYILRMAYCFTDELSKWFIAKELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNTIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPLCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCAKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIIAKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIRKNN 445
[Close]
BLAST of DNA primase large subunit vs. Planmine SMEST
Match: SMESG000030269.1 (SMESG000030269.1)

HSP 1 Score: 889.026 bits (2296), Expect = 0.000e+0
Identity = 424/443 (95.71%), Postives = 433/443 (97.74%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITKIKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQ 1352
            MEYK+SLSKKL+RNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSN G DIS+SM+DDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFM DNGIFV+EALPAEYKKFF IDNTN IIYKVPFLQVLDLVKSQKVKLHKGFAFL DSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNM+KITADQIDGLSVKSFPPCMQNVNS LKR SHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSC KIITSNPPQAGDCHGCPFQH+NVELIAQNLRKFANATSEQIESII K+KMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKIL+
Sbjct:    1 MEYKKSLSKKLLRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNVGRDISRSMSDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMSDNGIFVEEALPAEYKKFFHIDNTNTIIYKVPFLQVLDLVKSQKVKLHKGFAFLFDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMNKITADQIDGLSVKSFPPCMQNVNSVLKRYSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPYSCAKIITSNPPQAGDCHGCPFQHTNVELIAQNLRKFANATSEQIESIIAKVKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILK 443
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BLAST of DNA primase large subunit vs. Planmine SMEST
Match: SMESG000030252.1 (SMESG000030252.1)

HSP 1 Score: 532.717 bits (1371), Expect = 0.000e+0
Identity = 274/349 (78.51%), Postives = 280/349 (80.23%), Query Frame = 3 
Query:   24 MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYILRMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQEALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLKGIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGP 1070
            MEYKESLSKKL+RNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLST                                    L K+F +                      KFM DNGIFV+EALPAEYKKFF IDNTN IIYKVPFLQVLDLVKSQKVKLHKGFAFL DSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNM+KITA QIDGLSVKSFPPCMQNVNS LKRDS+VKHWGRMQYGLFLKGIGVPLEESLKF KKGFEEKCDSNTFAKKY YNIRHSY QEGKRVNYGP
Sbjct:    1 MEYKESLSKKLLRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLSEDYVKGRVEYSDQVYSRLSKLST------------------------------------LGKYFGSN---------------------KFMSDNGIFVEEALPAEYKKFFHIDNTNTIIYKVPFLQVLDLVKSQKVKLHKGFAFLFDSDICSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSSANNMNKITAYQIDGLSVKSFPPCMQNVNSVLKRDSYVKHWGRMQYGLFLKGIGVPLEESLKFRKKGFEEKCDSNTFAKKYTYNIRHSYVQEGKRVNYGP 292
The following BLAST results are available for this feature:
BLAST of DNA primase large subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRIM22.309e-11842.21DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC... [more]
PRIM25.240e-7148.87DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC... [more]
PRIM29.415e-2760.00DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC... [more]
PRIM21.797e-2343.75DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC... [more]
PRIM21.797e-2343.75DNA primase subunit 2 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of DNA primase large subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 4
Match NameE-valueIdentityDescription
pri-21.672e-7635.14DNA primase large subunit [Source:UniProtKB/Swiss... [more]
pri-21.672e-7635.14DNA primase large subunit [Source:UniProtKB/Swiss... [more]
pri-21.997e-5939.50DNA primase large subunit [Source:UniProtKB/Swiss... [more]
pri-21.997e-5939.50DNA primase large subunit [Source:UniProtKB/Swiss... [more]
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BLAST of DNA primase large subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
DNApol-alpha602.237e-8135.89gene:FBgn0259676 transcript:FBtr0078241[more]
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BLAST of DNA primase large subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
prim21.119e-11341.35DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
prim21.119e-11341.35DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
prim28.690e-2035.00DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
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BLAST of DNA primase large subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
trpv28.961e-11941.61transient receptor potential cation channel, subfa... [more]
trpv28.348e-11841.67transient receptor potential cation channel, subfa... [more]
trpv21.888e-10640.09transient receptor potential cation channel, subfa... [more]
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BLAST of DNA primase large subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Prim23.201e-11941.59DNA primase, p58 subunit [Source:MGI Symbol;Acc:MG... [more]
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BLAST of DNA primase large subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P33610|PRI2_MOUSE2.239e-11841.59DNA primase large subunit OS=Mus musculus OX=10090... [more]
sp|P49643|PRI2_HUMAN1.109e-11742.21DNA primase large subunit OS=Homo sapiens OX=9606 ... [more]
sp|O89044|PRI2_RAT1.571e-11741.36DNA primase large subunit OS=Rattus norvegicus OX=... [more]
sp|Q84WJ2|PRI2_ARATH3.337e-9640.18Probable DNA primase large subunit OS=Arabidopsis ... [more]
sp|Q9VPH2|PRI2_DROME2.243e-8035.89DNA primase large subunit OS=Drosophila melanogast... [more]
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BLAST of DNA primase large subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A183AJT31.554e-13343.99DNA primase large subunit OS=Echinostoma caproni O... [more]
A0A4Z2CMN72.470e-13143.80DNA primase large subunit OS=Schistosoma japonicum... [more]
C4QIH84.286e-13142.83DNA primase large subunit, putative OS=Schistosoma... [more]
A0A5J4N7U68.403e-13144.16DNA primase large subunit OS=Paragonimus westerman... [more]
A0A0R3S9S12.235e-13043.01DNA primase large subunit OS=Hymenolepis diminuta ... [more]
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BLAST of DNA primase large subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
prim23.026e-9838.84DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
prim29.734e-9737.99DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
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BLAST of DNA primase large subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
prim27.015e-10838.01DNA primase subunit 2 [Source:ZFIN;Acc:ZDB-GENE-05... [more]
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BLAST of DNA primase large subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
PRI24.309e-6231.80Subunit of DNA primase; DNA primase is required fo... [more]
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BLAST of DNA primase large subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO474374.892e-11341.03Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO474362.998e-1924.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DNA primase large subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
prim25.131e-11341.46DNA primase subunit 2 [Source:NCBI gene;Acc:101155... [more]
prim27.296e-10641.15DNA primase subunit 2 [Source:NCBI gene;Acc:101155... [more]
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BLAST of DNA primase large subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000059945.10.000e+098.65SMESG000059945.1[more]
SMESG000059950.10.000e+098.20SMESG000059950.1[more]
SMESG000030269.10.000e+095.71SMESG000030269.1[more]
SMESG000030252.10.000e+078.51SMESG000030252.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30036024 ID=SMED30036024|Name=DNA primase large subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1636bp
AGGGTTAAAAAATTAATTTGAATATGGAATACAAAGAAAGTTTAAGTAAA
AAACTTATGCGTAATAGGTTGCAGTTTTATAATATACCACCTACTGATAC
AGTTCCTCTTGACACCTTAGAAAATTTAGCTATCGACAGATTGAAAGTTC
TCAGATGCATTGATAACCTATCTGAAGATTACGTTAAAGGAAGAGTGGAA
TATAGTGATCAAGTTTACTCGCGACTTTCCAAACTTTCAACTTTAGGAAA
ATATTTTGTTTCTAACGCAGGAAGTGATATTTCGCAATCAATGAACGATG
ACATTTTGTCACACTATATTTTACGAATGGCATATTGTTTTACTGATGAA
CTAAGTAAATGGTTTATTGCTCAAGAATTGGATTTGTTTCAATATCGCTT
CAATGCGGAAAGATTAGCAAATCCTCATTCCATAAAGAAATTTATGTTCG
ATAATGGCATTTTCGTACAAGAGGCATTACCCGCAGAATACAAAAAATTC
TTTCAGATTGATAATACAAATATAATCATATATAAAGTACCGTTCCTTCA
AGTTTTAGATTTAGTTAAATCGCAGAAAGTTAAACTACATAAAGGGTTTG
CATTTTTATTAGACAGCGATATTTGCTCACTTGTATTGTGGCATTTTCGC
TCTTATTTATCTCAAGAACTCTCATATTTAAGATTGCATATTCATGAAAT
TGACGAAGAAGACAGATTAATGCCGATTCTTTCAAATTTAAATAAGCGCT
ACTTGGGTAAAGATTATTCATCCGCAAATAATATGGATAAAATAACGGCA
GATCAAATTGATGGATTATCTGTAAAATCATTTCCACCTTGCATGCAAAA
TGTTAATTCTGCTTTGAAACGCGACAGTCATGTAAAGCATTGGGGAAGAA
TGCAATACGGATTATTTTTGAAAGGTATTGGAGTACCATTAGAAGAATCT
CTCAAATTTTGGAAGAAAGGTTTCGAGGAGAAATGTGATTCCAACACTTT
TGCAAAGAAATATGCATATAACATTCGACATTCCTATGGGCAAGAAGGCA
AACGGGTTAATTACGGACCATATAGCTGTGTCAAAATTATCACATCAAAT
CCACCTCAGGCTGGAGATTGTCATGGATGCCCATTTCAACATTCAAATGT
TGAGTTAATTGCTCAAAATCTCAGAAAATTTGCAAATGCAACTTCAGAAC
AAATTGAATCTATTATTACAAAAATAAAAATGAAACAATTTCAAATTAGT
TGTCGAAATTATTTCAAATTGGTTCACGGATTGCCGGATAACTATCCCAT
CACAATAAATCATCCTAATGAATATTTTGAAGAGAGTCGAAAAATACTGC
AAAATAATTGATGTAATAAATATATATGTTTTAATGTTGACTTACATTTA
TTGCTATGAGATATTTCTATAGAAATATATTATTTACAACTGGGTCATTA
AATTTTGTATGTAGTTTGGATTAGAAATTTAGGATTTTATAAAGCTTAAA
ACCATTTTTGTGTGTTCTTTTTGGTTAATTCTTCAGCATGTTGAAAGGGA
ATAAATGTACAATTGATTAAATGTTCAGTATATTATATAATGTAATTTAT
ATTATATCTATAGAAATATAACATGTAAAACTGGAA
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protein sequence of SMED30036024-orf-1

>SMED30036024-orf-1 ID=SMED30036024-orf-1|Name=SMED30036024-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=446bp
MEYKESLSKKLMRNRLQFYNIPPTDTVPLDTLENLAIDRLKVLRCIDNLS
EDYVKGRVEYSDQVYSRLSKLSTLGKYFVSNAGSDISQSMNDDILSHYIL
RMAYCFTDELSKWFIAQELDLFQYRFNAERLANPHSIKKFMFDNGIFVQE
ALPAEYKKFFQIDNTNIIIYKVPFLQVLDLVKSQKVKLHKGFAFLLDSDI
CSLVLWHFRSYLSQELSYLRLHIHEIDEEDRLMPILSNLNKRYLGKDYSS
ANNMDKITADQIDGLSVKSFPPCMQNVNSALKRDSHVKHWGRMQYGLFLK
GIGVPLEESLKFWKKGFEEKCDSNTFAKKYAYNIRHSYGQEGKRVNYGPY
SCVKIITSNPPQAGDCHGCPFQHSNVELIAQNLRKFANATSEQIESIITK
IKMKQFQISCRNYFKLVHGLPDNYPITINHPNEYFEESRKILQNN*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000014zeta neoblast
PLANA:0000420parapharyngeal region
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR007238DNA_primase_lsu_euk/arc
IPR016558DNA_primase_lsu_euk
Vocabulary: biological process
TermDefinition
GO:0006269DNA replication, synthesis of RNA primer
GO:0006260DNA replication
Vocabulary: molecular function
TermDefinition
GO:0003896DNA primase activity
GO:0016779nucleotidyltransferase activity
GO:0051536iron-sulfur cluster binding
GO:00515394 iron, 4 sulfur cluster binding
GO:0003677DNA binding
GO:0003899DNA-directed 5'-3' RNA polymerase activity
GO:0016740transferase activity
GO:0046872metal ion binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR016558DNA primase, large subunit, eukaryoticPIRSFPIRSF009449DNA_primase_largecoord: 2..445
e-value: 2.8E-134
score: 446.2
IPR016558DNA primase, large subunit, eukaryoticCDDcd07322PriL_PriS_Eukaryoticcoord: 18..438
e-value: 1.08296E-157
score: 449.405
NoneNo IPR availableGENE3DG3DSA:1.20.930.80coord: 1..239
e-value: 3.5E-62
score: 212.1
IPR007238DNA primase large subunit, eukaryotic/archaealPFAMPF04104DNA_primase_lrgcoord: 170..435
e-value: 9.2E-79
score: 264.6
IPR007238DNA primase large subunit, eukaryotic/archaealPANTHERPTHR10537DNA PRIMASE LARGE SUBUNITcoord: 14..444