Histone H2A

Overview
NameHistone H2A
Smed IDSMED30036016
Length (bp)602
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Histone H2A (SMED30036016) t-SNE clustered cells

Violin plots show distribution of expression levels for Histone H2A (SMED30036016) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Histone H2A (SMED30036016) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Histone H2A (SMED30036016) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30036016

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 11

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30036016SMESG000018807.1 SmedASXL_006547SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30036016SMESG000018807.1 dd_Smed_v4_7383_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30036016SMESG000018807.1 dd_Smed_v4_7383_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neuronSMED30036016SMESG000018807.1 dd_Smed_v4_7383_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
muscle cellSMED30036016SMESG000018807.1 dd_Smed_v4_7383_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30036016SMESG000018807.1 Contig51128newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30036016SMESG000018807.1 Contig51128uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30036016SMESG000044864.1 SMESG000038983.1 SMESG000018807.1 SMESG000007950.1 Contig17088newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30036016SMESG000044864.1 SMESG000038983.1 SMESG000018807.1 SMESG000007950.1 Contig17088uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
head regionSMED30036016SMESG000018807.1 dd_Smed_v6_7383_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
photoreceptor neuronSMED30036016SMESG000018807.1 SMED30036016smed_20140614PMID:22884275
Lapan et al., 2012		whole organism asexual adult colorimetric in situ hybridization evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Histone H2A vs. Ensembl Human
Match: H2AC20 (H2A clustered histone 20 [Source:HGNC Symbol;Acc:HGNC:4738])

HSP 1 Score: 153.68 bits (387), Expect = 1.128e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Human
Match: H2AJ (H2A.J histone [Source:HGNC Symbol;Acc:HGNC:14456])

HSP 1 Score: 153.68 bits (387), Expect = 1.141e-47
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Human
Match: H2AJ (H2A.J histone [Source:HGNC Symbol;Acc:HGNC:14456])

HSP 1 Score: 153.68 bits (387), Expect = 1.141e-47
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Human
Match: H2AC14 (H2A clustered histone 14 [Source:HGNC Symbol;Acc:HGNC:4727])

HSP 1 Score: 153.295 bits (386), Expect = 1.748e-47
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Human
Match: H2AC19 (H2A clustered histone 19 [Source:HGNC Symbol;Acc:HGNC:29668])

HSP 1 Score: 153.295 bits (386), Expect = 1.820e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Celegans
Match: his-35 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485])

HSP 1 Score: 146.362 bits (368), Expect = 4.053e-45
Identity = 90/98 (91.84%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRI PRHLQLA+RNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   22 RAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Celegans
Match: his-35 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485])

HSP 1 Score: 146.362 bits (368), Expect = 4.053e-45
Identity = 90/98 (91.84%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRI PRHLQLA+RNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   22 RAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Celegans
Match: his-68 (Histone H2A [Source:UniProtKB/Swiss-Prot;Acc:P09588])

HSP 1 Score: 145.976 bits (367), Expect = 5.558e-45
Identity = 90/98 (91.84%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRI PRHLQLA+RNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   22 RAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Celegans
Match: his-65 (Histone H2A [Source:UniProtKB/Swiss-Prot;Acc:P09588])

HSP 1 Score: 145.976 bits (367), Expect = 5.558e-45
Identity = 90/98 (91.84%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRI PRHLQLA+RNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   22 RAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Celegans
Match: his-61 (Histone H2A [Source:UniProtKB/Swiss-Prot;Acc:P09588])

HSP 1 Score: 145.976 bits (367), Expect = 5.558e-45
Identity = 90/98 (91.84%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRI PRHLQLA+RNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   22 RAGLQFPVGRLHRILRKGNYAQRVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIAPRHLQLAVRNDEELNKLLAGVTIAQGGVLPNIQAVLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Fly
Match: His2A:CG33853 (gene:FBgn0053853 transcript:FBtr0091857)

HSP 1 Score: 152.14 bits (383), Expect = 1.973e-47
Identity = 93/98 (94.90%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYAERVGAGAPVYLAAV+EYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Fly
Match: His2A:CG33859 (gene:FBgn0053859 transcript:FBtr0091863)

HSP 1 Score: 152.14 bits (383), Expect = 1.973e-47
Identity = 93/98 (94.90%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYAERVGAGAPVYLAAV+EYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Fly
Match: His2A:CG33856 (gene:FBgn0053856 transcript:FBtr0091860)

HSP 1 Score: 152.14 bits (383), Expect = 1.973e-47
Identity = 93/98 (94.90%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYAERVGAGAPVYLAAV+EYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Fly
Match: His2A:CG33850 (gene:FBgn0053850 transcript:FBtr0091854)

HSP 1 Score: 152.14 bits (383), Expect = 2.083e-47
Identity = 93/98 (94.90%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYAERVGAGAPVYLAAV+EYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Fly
Match: His2A:CG33847 (gene:FBgn0053847 transcript:FBtr0091851)

HSP 1 Score: 152.14 bits (383), Expect = 2.083e-47
Identity = 93/98 (94.90%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYAERVGAGAPVYLAAV+EYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Zebrafish
Match: hist1h2a11 (histone cluster 1 H2A family member 11 [Source:ZFIN;Acc:ZDB-GENE-081205-1])

HSP 1 Score: 152.91 bits (385), Expect = 1.579e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Zebrafish
Match: hist1h2a11 (histone cluster 1 H2A family member 11 [Source:ZFIN;Acc:ZDB-GENE-081205-1])

HSP 1 Score: 152.91 bits (385), Expect = 1.579e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Zebrafish
Match: hist1h2a11 (histone cluster 1 H2A family member 11 [Source:ZFIN;Acc:ZDB-GENE-081205-1])

HSP 1 Score: 152.91 bits (385), Expect = 1.579e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Zebrafish
Match: hist1h2a11 (histone cluster 1 H2A family member 11 [Source:ZFIN;Acc:ZDB-GENE-081205-1])

HSP 1 Score: 152.91 bits (385), Expect = 1.579e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Zebrafish
Match: hist1h2a11 (histone cluster 1 H2A family member 11 [Source:ZFIN;Acc:ZDB-GENE-081205-1])

HSP 1 Score: 152.91 bits (385), Expect = 1.579e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Xenopus
Match: hist1h2ah (histone H2A type 1-like [Source:NCBI gene;Acc:108644455])

HSP 1 Score: 154.836 bits (390), Expect = 4.866e-48
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Xenopus
Match: hist1h2ah (histone H2A type 1-like [Source:NCBI gene;Acc:108644455])

HSP 1 Score: 154.836 bits (390), Expect = 4.866e-48
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Xenopus
Match: tgfbr2 (transforming growth factor beta receptor II [Source:Xenbase;Acc:XB-GENE-485606])

HSP 1 Score: 154.451 bits (389), Expect = 5.310e-48
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Xenopus
Match: cldn19 (claudin 19 [Source:Xenbase;Acc:XB-GENE-954659])

HSP 1 Score: 154.451 bits (389), Expect = 5.903e-48
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   23 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 120
[Close]
BLAST of Histone H2A vs. Ensembl Xenopus
Match: trps1 (transcriptional repressor GATA binding 1 [Source:Xenbase;Acc:XB-GENE-1013667])

HSP 1 Score: 154.451 bits (389), Expect = 5.986e-48
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Mouse
Match: H2ac20 (H2A clustered histone 20 [Source:MGI Symbol;Acc:MGI:2448316])

HSP 1 Score: 153.68 bits (387), Expect = 7.747e-48
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Mouse
Match: H2ac18 (H2A clustered histone 18 [Source:MGI Symbol;Acc:MGI:96097])

HSP 1 Score: 153.295 bits (386), Expect = 1.250e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Mouse
Match: H2ac19 (H2A clustered histone 19 [Source:MGI Symbol;Acc:MGI:2448283])

HSP 1 Score: 153.295 bits (386), Expect = 1.250e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Mouse
Match: H2aj (H2J.A histone [Source:MGI Symbol;Acc:MGI:3606192])

HSP 1 Score: 153.295 bits (386), Expect = 1.411e-47
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Mouse
Match: H2aj (H2J.A histone [Source:MGI Symbol;Acc:MGI:3606192])

HSP 1 Score: 152.525 bits (384), Expect = 2.341e-47
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. UniProt/SwissProt
Match: sp|P06897|H2A1_XENLA (Histone H2A type 1 OS=Xenopus laevis OX=8355 PE=1 SV=2)

HSP 1 Score: 154.451 bits (389), Expect = 3.206e-47
Identity = 92/98 (93.88%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. UniProt/SwissProt
Match: sp|P70082|H2AJ_CHICK (Histone H2A.J OS=Gallus gallus OX=9031 GN=H2A-IX PE=3 SV=1)

HSP 1 Score: 154.066 bits (388), Expect = 4.807e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. UniProt/SwissProt
Match: sp|Q64523|H2A2C_MOUSE (Histone H2A type 2-C OS=Mus musculus OX=10090 GN=H2ac20 PE=1 SV=3)

HSP 1 Score: 153.68 bits (387), Expect = 5.419e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. UniProt/SwissProt
Match: sp|Q16777|H2A2C_HUMAN (Histone H2A type 2-C OS=Homo sapiens OX=9606 GN=H2AC20 PE=1 SV=4)

HSP 1 Score: 153.68 bits (387), Expect = 5.419e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. UniProt/SwissProt
Match: sp|A1A4R1|H2A2C_BOVIN (Histone H2A type 2-C OS=Bos taurus OX=9913 GN=H2AC20 PE=2 SV=1)

HSP 1 Score: 153.68 bits (387), Expect = 5.419e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVY+AAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. TrEMBL
Match: Q8I0L7 (Histone H2A OS=Oikopleura dioica OX=34765 GN=H2A.1 PE=2 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 2.959e-45
Identity = 94/99 (94.95%), Postives = 98/99 (98.99%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            VRAGLQFPVGR+HRMLRKGNYAERVGAGAPVYLAAVLEYL+AEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ++LLP
Sbjct:   19 VRAGLQFPVGRVHRMLRKGNYAERVGAGAPVYLAAVLEYLSAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAILLP 117
[Close]
BLAST of Histone H2A vs. TrEMBL
Match: Q8I0X8 (Histone H2A (Fragment) OS=Oikopleura dioica OX=34765 GN=H2a.1b PE=2 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 3.195e-45
Identity = 94/99 (94.95%), Postives = 98/99 (98.99%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            VRAGLQFPVGR+HRMLRKGNYAERVGAGAPVYLAAVLEYL+AEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ++LLP
Sbjct:   12 VRAGLQFPVGRVHRMLRKGNYAERVGAGAPVYLAAVLEYLSAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAILLP 110
[Close]
BLAST of Histone H2A vs. TrEMBL
Match: E4YCH5 (Histone H2A OS=Oikopleura dioica OX=34765 GN=GSOID_T00021142001 PE=3 SV=1)

HSP 1 Score: 155.221 bits (391), Expect = 3.264e-45
Identity = 94/99 (94.95%), Postives = 98/99 (98.99%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            VRAGLQFPVGR+HRMLRKGNYAERVGAGAPVYLAAVLEYL+AEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ++LLP
Sbjct:   19 VRAGLQFPVGRVHRMLRKGNYAERVGAGAPVYLAAVLEYLSAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAILLP 117
[Close]
BLAST of Histone H2A vs. TrEMBL
Match: U6JBU6 (Histone H2A OS=Echinococcus granulosus OX=6210 GN=EGR_03046 PE=3 SV=1)

HSP 1 Score: 155.606 bits (392), Expect = 3.948e-45
Identity = 93/99 (93.94%), Postives = 98/99 (98.99%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            +RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAV+EYLAAEVLELAGNAARDNKKTRI+PRHLQLAIRNDEELNKLL SVTIAQGGVLPNIQSVLLP
Sbjct:   20 IRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTRIVPRHLQLAIRNDEELNKLLSSVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. TrEMBL
Match: A0A1L8G727 (Histone H2A OS=Xenopus laevis OX=8355 GN=XELAEV_18026403mg PE=3 SV=1)

HSP 1 Score: 154.836 bits (390), Expect = 6.777e-45
Identity = 92/99 (92.93%), Postives = 96/99 (96.97%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
             RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQSVLLP
Sbjct:   20 TRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQSVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Cavefish
Match: ENSAMXT00000040985.1 (pep primary_assembly:Astyanax_mexicanus-2.0:20:27523804:27524807:1 gene:ENSAMXG00000035879.1 transcript:ENSAMXT00000040985.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.295 bits (386), Expect = 1.014e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   23 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 120
[Close]
BLAST of Histone H2A vs. Ensembl Cavefish
Match: ENSAMXT00000025817.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000522.1:47764:48404:-1 gene:ENSAMXG00000025091.2 transcript:ENSAMXT00000025817.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.295 bits (386), Expect = 1.207e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   23 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 120
[Close]
BLAST of Histone H2A vs. Ensembl Cavefish
Match: ENSAMXT00000050088.1 (pep primary_assembly:Astyanax_mexicanus-2.0:21:10166233:10171033:1 gene:ENSAMXG00000038836.1 transcript:ENSAMXT00000050088.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.91 bits (385), Expect = 1.708e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   24 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 121
[Close]
BLAST of Histone H2A vs. Ensembl Cavefish
Match: ENSAMXT00000026274.2 (pep primary_assembly:Astyanax_mexicanus-2.0:21:10145526:10150789:1 gene:ENSAMXG00000025549.2 transcript:ENSAMXT00000026274.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.525 bits (384), Expect = 2.539e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Cavefish
Match: h2ax (H2A.X variant histone [Source:NCBI gene;Acc:394048])

HSP 1 Score: 152.14 bits (383), Expect = 3.033e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011253.1 (pep scaffold:Pmarinus_7.0:GL479154:926813:927238:-1 gene:ENSPMAG00000010226.1 transcript:ENSPMAT00000011253.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.68 bits (387), Expect = 2.064e-48
Identity = 92/98 (93.88%), Postives = 97/98 (98.98%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005338.1 (pep scaffold:Pmarinus_7.0:GL476820:708214:709027:-1 gene:ENSPMAG00000004859.1 transcript:ENSPMAT00000005338.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 150.984 bits (380), Expect = 1.942e-47
Identity = 89/98 (90.82%), Postives = 97/98 (98.98%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKL+G VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002388.1 (pep scaffold:Pmarinus_7.0:GL476925:193851:194294:1 gene:ENSPMAG00000002177.1 transcript:ENSPMAT00000002388.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 149.828 bits (377), Expect = 5.408e-47
Identity = 89/98 (90.82%), Postives = 97/98 (98.98%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYA+RVGAGAPVYLAAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKL+G VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAQRVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008684.1 (pep scaffold:Pmarinus_7.0:GL488596:2418:2939:-1 gene:ENSPMAG00000007861.1 transcript:ENSPMAT00000008684.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 148.673 bits (374), Expect = 1.793e-46
Identity = 89/98 (90.82%), Postives = 97/98 (98.98%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYA+RVGAGAPVYLAAVLEYL+AE+LELAGNAARDNKKTRIIPR+LQLA+RNDEELNKL+G VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRIHRLLRKGNYAQRVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRNLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011166.1 (pep scaffold:Pmarinus_7.0:GL476820:1027708:1028088:1 gene:ENSPMAG00000010139.1 transcript:ENSPMAT00000011166.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 146.747 bits (369), Expect = 8.210e-46
Identity = 88/98 (89.80%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+L KGNYA+RVGAGAPVYLAAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKL+G VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLCKGNYAQRVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLMGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Yeast
Match: HTA2 (Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical (see also HTA1) subtypes; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p [Source:SGD;Acc:S000000099])

HSP 1 Score: 139.428 bits (350), Expect = 3.337e-43
Identity = 83/99 (83.84%), Postives = 93/99 (93.94%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
             +AGL FPVGR+HR+LR+GNYA+R+G+GAPVYL AVLEYLAAE+LELAGNAARDNKKTRIIPRHLQLAIRND+ELNKLLG+VTIAQGGVLPNI   LLP
Sbjct:   21 AKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Yeast
Match: HTA1 (Histone H2A; core histone protein required for chromatin assembly and chromosome function; one of two nearly identical subtypes (see also HTA2); DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p; N-terminally propionylated in vivo [Source:SGD;Acc:S000002633])

HSP 1 Score: 139.428 bits (350), Expect = 3.337e-43
Identity = 83/99 (83.84%), Postives = 93/99 (93.94%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
             +AGL FPVGR+HR+LR+GNYA+R+G+GAPVYL AVLEYLAAE+LELAGNAARDNKKTRIIPRHLQLAIRND+ELNKLLG+VTIAQGGVLPNI   LLP
Sbjct:   21 AKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLP 119
[Close]
BLAST of Histone H2A vs. Ensembl Yeast
Match: HTZ1 (Histone variant H2AZ; exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin; Htz1p-containing nucleosomes facilitate RNA Pol II passage by affecting correct assembly and modification status of RNA Pol II elongation complexes and by favoring efficient nucleosome remodeling [Source:SGD;Acc:S000005372])

HSP 1 Score: 81.6481 bits (200), Expect = 1.376e-20
Identity = 65/99 (65.66%), Postives = 72/99 (72.73%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRML-RKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLL 455
             RAGLQFPVGRI R L R      RVG+ A +YL AVLEYL AEVLELAGNAA+D K  RI PRHLQLAIR D+EL+ L+   TIA GGVLP+I   LL
Sbjct:   27 ARAGLQFPVGRIKRYLKRHATGRTRVGSKAAIYLTAVLEYLTAEVLELAGNAAKDLKVKRITPRHLQLAIRGDDELDSLI-RATIASGGVLPHINKALL 124
[Close]
BLAST of Histone H2A vs. Ensembl Nematostella
Match: EDO31130 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7SYT5])

HSP 1 Score: 151.754 bits (382), Expect = 1.238e-47
Identity = 90/99 (90.91%), Postives = 96/99 (96.97%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
             RAGLQFPVGR+HR LRKGNYAERVGAGAPVY+AAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   19 ARAGLQFPVGRVHRFLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Nematostella
Match: EDO48283 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RJL4])

HSP 1 Score: 151.369 bits (381), Expect = 1.695e-47
Identity = 90/98 (91.84%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR+LRKGNYAERVGAGAPVY+AAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELN+LL  VTIAQGGVLPNIQSVLLP
Sbjct:   20 RAGLQFPVGRIHRLLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNRLLSGVTIAQGGVLPNIQSVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Nematostella
Match: EDO30157 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7T1L1])

HSP 1 Score: 147.517 bits (371), Expect = 3.898e-46
Identity = 90/98 (91.84%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR LRKGNYAERVGAGAPVYLAAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELN+LL  VTIAQGGVLPNIQ+VLLP
Sbjct:   13 RAGLQFPVGRIHRHLRKGNYAERVGAGAPVYLAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNRLLHGVTIAQGGVLPNIQAVLLP 110
[Close]
BLAST of Histone H2A vs. Ensembl Nematostella
Match: EDO48304 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RJM1])

HSP 1 Score: 147.902 bits (372), Expect = 4.507e-46
Identity = 89/98 (90.82%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR LRKGNYAERVGAGAPVY+AAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELN+LL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRHLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNRLLHGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Nematostella
Match: EDO48403 (Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RJM1])

HSP 1 Score: 147.902 bits (372), Expect = 4.507e-46
Identity = 89/98 (90.82%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR LRKGNYAERVGAGAPVY+AAVLEYL+AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELN+LL  VTIAQGGVLPNIQ+VLLP
Sbjct:   20 RAGLQFPVGRIHRHLRKGNYAERVGAGAPVYMAAVLEYLSAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNRLLHGVTIAQGGVLPNIQAVLLP 117
[Close]
BLAST of Histone H2A vs. Ensembl Medaka
Match: ENSORLT00000036997.1 (pep primary_assembly:ASM223467v1:1:8896657:8898783:1 gene:ENSORLG00000027232.1 transcript:ENSORLT00000036997.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 153.295 bits (386), Expect = 1.551e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Medaka
Match: ENSORLT00000000848.2 (pep primary_assembly:ASM223467v1:14:15235538:15240676:1 gene:ENSORLG00000000686.2 transcript:ENSORLT00000000848.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.91 bits (385), Expect = 1.909e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Medaka
Match: ENSORLT00000042228.1 (pep primary_assembly:ASM223467v1:23:22958305:22963215:1 gene:ENSORLG00000027073.1 transcript:ENSORLT00000042228.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.91 bits (385), Expect = 1.954e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Medaka
Match: ENSORLT00000043619.1 (pep primary_assembly:ASM223467v1:1:2176285:2181192:1 gene:ENSORLG00000022228.1 transcript:ENSORLT00000043619.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.525 bits (384), Expect = 2.021e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Ensembl Medaka
Match: ENSORLT00000037938.1 (pep primary_assembly:ASM223467v1:23:22957103:22961437:-1 gene:ENSORLG00000023963.1 transcript:ENSORLT00000037938.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 152.525 bits (384), Expect = 2.134e-47
Identity = 91/98 (92.86%), Postives = 96/98 (97.96%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGR+HR+LRKGNYAERVGAGAPVYLAAVLEYL AE+LELAGNAARDNKKTRIIPRHLQLA+RNDEELNKLLG VTIAQGGVLPNIQ+VLLP
Sbjct:   21 RAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLP 118
[Close]
BLAST of Histone H2A vs. Planmine SMEST
Match: SMESG000018807.1 (SMESG000018807.1)

HSP 1 Score: 159.844 bits (403), Expect = 1.759e-50
Identity = 99/99 (100.00%), Postives = 99/99 (100.00%), Query Frame = 3 
Query:  162 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            VRAGLQFPVGRIHRMLRKGNYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP
Sbjct:   19 VRAGLQFPVGRIHRMLRKGNYAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 117
[Close]
BLAST of Histone H2A vs. Planmine SMEST
Match: SMESG000067932.1 (SMESG000067932.1)

HSP 1 Score: 147.902 bits (372), Expect = 9.031e-46
Identity = 91/98 (92.86%), Postives = 95/98 (96.94%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR LRKGN+AERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKK+RIIPRHLQLAIRNDEELNKLLG VTI+QGGV+PNIQS LLP
Sbjct:   22 RAGLQFPVGRIHRKLRKGNFAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGGVTISQGGVIPNIQSALLP 119
[Close]
BLAST of Histone H2A vs. Planmine SMEST
Match: SMESG000006040.1 (SMESG000006040.1)

HSP 1 Score: 147.517 bits (371), Expect = 1.105e-45
Identity = 92/98 (93.88%), Postives = 94/98 (95.92%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR LRKGN+AERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKK+RIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ  LLP
Sbjct:   21 RAGLQFPVGRIHRKLRKGNFAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQISLLP 118
[Close]
BLAST of Histone H2A vs. Planmine SMEST
Match: SMESG000006040.1 (SMESG000006040.1)

HSP 1 Score: 147.132 bits (370), Expect = 1.943e-45
Identity = 92/98 (93.88%), Postives = 94/98 (95.92%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGLQFPVGRIHR LRKGN+AERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKK+RIIPRHLQLAIRNDEELNKLLG VTIAQGGVLPNIQ  LLP
Sbjct:   21 RAGLQFPVGRIHRKLRKGNFAERVGAGAPVYLAAVLEYLAAEVLELAGNAARDNKKSRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQISLLP 118
[Close]
BLAST of Histone H2A vs. Planmine SMEST
Match: SMESG000072071.1 (SMESG000072071.1)

HSP 1 Score: 124.02 bits (310), Expect = 3.025e-36
Identity = 72/98 (73.47%), Postives = 88/98 (89.80%), Query Frame = 3 
Query:  165 RAGLQFPVGRIHRMLRKGNYAERVGAGAPXXXXXXXXXXXXXXXXXXGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSVTIAQGGVLPNIQSVLLP 458
            RAGL FPVGR+HR+LRKG + ER+G GAPVY++A+LEYL AE+LELAGNAARDNKK+RI PRH+ LAI+ND EL++LL SVTI+QGGV+PNIQ+ LLP
Sbjct:   23 RAGLTFPVGRVHRLLRKGKFGERIGHGAPVYMSAILEYLTAEILELAGNAARDNKKSRIAPRHILLAIKNDSELSELLKSVTISQGGVMPNIQNTLLP 120
The following BLAST results are available for this feature:
BLAST of Histone H2A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
H2AC201.128e-4792.86H2A clustered histone 20 [Source:HGNC Symbol;Acc:H... [more]
H2AJ1.141e-4793.88H2A.J histone [Source:HGNC Symbol;Acc:HGNC:14456][more]
H2AJ1.141e-4793.88H2A.J histone [Source:HGNC Symbol;Acc:HGNC:14456][more]
H2AC141.748e-4793.88H2A clustered histone 14 [Source:HGNC Symbol;Acc:H... [more]
H2AC191.820e-4792.86H2A clustered histone 19 [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Histone H2A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
his-354.053e-4591.84Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485][more]
his-354.053e-4591.84Histone H2A [Source:UniProtKB/TrEMBL;Acc:Q27485][more]
his-685.558e-4591.84Histone H2A [Source:UniProtKB/Swiss-Prot;Acc:P095... [more]
his-655.558e-4591.84Histone H2A [Source:UniProtKB/Swiss-Prot;Acc:P095... [more]
his-615.558e-4591.84Histone H2A [Source:UniProtKB/Swiss-Prot;Acc:P095... [more]
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BLAST of Histone H2A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
His2A:CG338531.973e-4794.90gene:FBgn0053853 transcript:FBtr0091857[more]
His2A:CG338591.973e-4794.90gene:FBgn0053859 transcript:FBtr0091863[more]
His2A:CG338561.973e-4794.90gene:FBgn0053856 transcript:FBtr0091860[more]
His2A:CG338502.083e-4794.90gene:FBgn0053850 transcript:FBtr0091854[more]
His2A:CG338472.083e-4794.90gene:FBgn0053847 transcript:FBtr0091851[more]
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BLAST of Histone H2A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hist1h2a111.579e-4792.86histone cluster 1 H2A family member 11 [Source:ZFI... [more]
hist1h2a111.579e-4792.86histone cluster 1 H2A family member 11 [Source:ZFI... [more]
hist1h2a111.579e-4792.86histone cluster 1 H2A family member 11 [Source:ZFI... [more]
hist1h2a111.579e-4792.86histone cluster 1 H2A family member 11 [Source:ZFI... [more]
hist1h2a111.579e-4792.86histone cluster 1 H2A family member 11 [Source:ZFI... [more]
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BLAST of Histone H2A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hist1h2ah4.866e-4893.88histone H2A type 1-like [Source:NCBI gene;Acc:1086... [more]
hist1h2ah4.866e-4893.88histone H2A type 1-like [Source:NCBI gene;Acc:1086... [more]
tgfbr25.310e-4893.88transforming growth factor beta receptor II [Sourc... [more]
cldn195.903e-4893.88claudin 19 [Source:Xenbase;Acc:XB-GENE-954659][more]
trps15.986e-4893.88transcriptional repressor GATA binding 1 [Source:X... [more]
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BLAST of Histone H2A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
H2ac207.747e-4892.86H2A clustered histone 20 [Source:MGI Symbol;Acc:MG... [more]
H2ac181.250e-4792.86H2A clustered histone 18 [Source:MGI Symbol;Acc:MG... [more]
H2ac191.250e-4792.86H2A clustered histone 19 [Source:MGI Symbol;Acc:MG... [more]
H2aj1.411e-4793.88H2J.A histone [Source:MGI Symbol;Acc:MGI:3606192][more]
H2aj2.341e-4793.88H2J.A histone [Source:MGI Symbol;Acc:MGI:3606192][more]
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BLAST of Histone H2A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P06897|H2A1_XENLA3.206e-4793.88Histone H2A type 1 OS=Xenopus laevis OX=8355 PE=1 ... [more]
sp|P70082|H2AJ_CHICK4.807e-4792.86Histone H2A.J OS=Gallus gallus OX=9031 GN=H2A-IX P... [more]
sp|Q64523|H2A2C_MOUSE5.419e-4792.86Histone H2A type 2-C OS=Mus musculus OX=10090 GN=H... [more]
sp|Q16777|H2A2C_HUMAN5.419e-4792.86Histone H2A type 2-C OS=Homo sapiens OX=9606 GN=H2... [more]
sp|A1A4R1|H2A2C_BOVIN5.419e-4792.86Histone H2A type 2-C OS=Bos taurus OX=9913 GN=H2AC... [more]
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BLAST of Histone H2A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
Q8I0L72.959e-4594.95Histone H2A OS=Oikopleura dioica OX=34765 GN=H2A.1... [more]
Q8I0X83.195e-4594.95Histone H2A (Fragment) OS=Oikopleura dioica OX=347... [more]
E4YCH53.264e-4594.95Histone H2A OS=Oikopleura dioica OX=34765 GN=GSOID... [more]
U6JBU63.948e-4593.94Histone H2A OS=Echinococcus granulosus OX=6210 GN=... [more]
A0A1L8G7276.777e-4592.93Histone H2A OS=Xenopus laevis OX=8355 GN=XELAEV_18... [more]
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BLAST of Histone H2A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000040985.11.014e-4792.86pep primary_assembly:Astyanax_mexicanus-2.0:20:275... [more]
ENSAMXT00000025817.21.207e-4792.86pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000050088.11.708e-4792.86pep primary_assembly:Astyanax_mexicanus-2.0:21:101... [more]
ENSAMXT00000026274.22.539e-4792.86pep primary_assembly:Astyanax_mexicanus-2.0:21:101... [more]
h2ax3.033e-4792.86H2A.X variant histone [Source:NCBI gene;Acc:394048... [more]
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BLAST of Histone H2A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000011253.12.064e-4893.88pep scaffold:Pmarinus_7.0:GL479154:926813:927238:-... [more]
ENSPMAT00000005338.11.942e-4790.82pep scaffold:Pmarinus_7.0:GL476820:708214:709027:-... [more]
ENSPMAT00000002388.15.408e-4790.82pep scaffold:Pmarinus_7.0:GL476925:193851:194294:1... [more]
ENSPMAT00000008684.11.793e-4690.82pep scaffold:Pmarinus_7.0:GL488596:2418:2939:-1 ge... [more]
ENSPMAT00000011166.18.210e-4689.80pep scaffold:Pmarinus_7.0:GL476820:1027708:1028088... [more]
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BLAST of Histone H2A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
HTA23.337e-4383.84Histone H2A; core histone protein required for chr... [more]
HTA13.337e-4383.84Histone H2A; core histone protein required for chr... [more]
HTZ11.376e-2065.66Histone variant H2AZ; exchanged for histone H2A in... [more]
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BLAST of Histone H2A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO311301.238e-4790.91Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7SYT5][more]
EDO482831.695e-4791.84Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RJL4][more]
EDO301573.898e-4691.84Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7T1L1][more]
EDO483044.507e-4690.82Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RJM1][more]
EDO484034.507e-4690.82Histone H2A [Source:UniProtKB/TrEMBL;Acc:A7RJM1][more]
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BLAST of Histone H2A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000036997.11.551e-4792.86pep primary_assembly:ASM223467v1:1:8896657:8898783... [more]
ENSORLT00000000848.21.909e-4792.86pep primary_assembly:ASM223467v1:14:15235538:15240... [more]
ENSORLT00000042228.11.954e-4792.86pep primary_assembly:ASM223467v1:23:22958305:22963... [more]
ENSORLT00000043619.12.021e-4792.86pep primary_assembly:ASM223467v1:1:2176285:2181192... [more]
ENSORLT00000037938.12.134e-4792.86pep primary_assembly:ASM223467v1:23:22957103:22961... [more]
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BLAST of Histone H2A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000018807.11.759e-50100.00SMESG000018807.1[more]
SMESG000067932.19.031e-4692.86SMESG000067932.1[more]
SMESG000006040.11.105e-4593.88SMESG000006040.1[more]
SMESG000006040.11.943e-4593.88SMESG000006040.1[more]
SMESG000072071.13.025e-3673.47SMESG000072071.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30036016 ID=SMED30036016|Name=Histone H2A|organism=Schmidtea mediterranea sexual|type=transcript|length=602bp
CGACACAATTGCCTGTTTCTTTTAGTTTATCAACAAATATAAACTTATTT
TGAAAACATTTACCTTAGAATTTATTTAATTATAATTTATAATAAATTTT
CTTTATTATGTCTGGTCGTGGCAAAGGTGGCAAAAGTAGAAATAAAGCAA
AAAGTAGATCAGTAAGAGCTGGTTTACAGTTCCCAGTTGGCCGAATTCAC
AGAATGTTAAGAAAAGGAAATTACGCAGAGCGAGTTGGTGCTGGTGCACC
GGTTTATTTGGCAGCAGTTCTAGAATATTTGGCAGCAGAAGTGTTAGAAT
TAGCTGGAAATGCAGCACGCGATAACAAGAAAACAAGAATAATACCCAGA
CATTTACAACTTGCAATTCGAAATGACGAGGAACTTAACAAATTATTGGG
GAGTGTTACTATTGCCCAAGGTGGTGTTTTACCAAACATTCAATCAGTAC
TTTTACCGAAAAAGACTTCAAATGATAAAAAAAAGAATAAGATTCAATAT
TTTTTTTATAATATTAATATTTAGATTTATTGTCAGCTTATTGTGATTAT
TACTGATCTTACTAGTTATTCAATTATATGTTGTTATTTTTATTATTTCG
TG
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protein sequence of SMED30036016-orf-1

>SMED30036016-orf-1 ID=SMED30036016-orf-1|Name=SMED30036016-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=139bp
MSGRGKGGKSRNKAKSRSVRAGLQFPVGRIHRMLRKGNYAERVGAGAPVY
LAAVLEYLAAEVLELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGSV
TIAQGGVLPNIQSVLLPKKTSNDKKKNKIQYFFYNINI*
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Aliases
The feature 'Histone H2A' has the following synonyms
Synonym
Smed_09274
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000017photoreceptor neuron
PLANA:0000099neuron
PLANA:0000101muscle cell
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR002119Histone_H2A
IPR009072Histone-fold
IPR032454Histone_H2A_C
IPR007125Histone_H2A/H2B/H3
IPR032458Histone_H2A_CS
Vocabulary: cellular component
TermDefinition
GO:0000786nucleosome
GO:0005634nucleus
GO:0005694chromosome
Vocabulary: molecular function
TermDefinition
GO:0003677DNA binding
GO:0046982protein heterodimerization activity