Actinin alpha 4

Overview


Name	Actinin alpha 4
Smed ID	SMED30035939
Length (bp)	3039

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Actinin alpha 4 (SMED30035939) t-SNE clustered cells

Violin plots show distribution of expression levels for Actinin alpha 4 (SMED30035939) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Actinin alpha 4 (SMED30035939) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Actinin alpha 4 (SMED30035939) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035939

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 21

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
pharynx	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30035939	SMESG000074430.1	dd_Smed_v4_7964_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig48431	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig48431	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig49277	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig49277	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig45090	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig45090	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig34477	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig34477	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig31657	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035939	SMESG000074430.1	Contig31657	newmark_ests	PMID:29674431 Fincher et al., 2018
glial cell	SMED30035939	SMESG000074430.1	dd_Smed_v6_7964_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
reproductive organ	SMED30035939	SMESG000074430.1	Contig34477	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30035939	SMESG000074430.1	Contig34477	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 616.69 bits (1589), Expect = 0.000e+0
Identity = 325/888 (36.60%), Postives = 510/888 (57.43%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS YYHA    +K +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D   +  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A E FK+T+ EA  E   + ++ + + +++ +  ++    NPY+ + + +++  W ++++ +P RD++L+E L +Q   +  +  F+  +  +      ++ +I +S   +  + +  +  + + ++  +    + +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP   S  G     LDY  FS  L+
Sbjct:   17 DEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDLVYTARPDERAIMTYVSCYYHAFAGAQKAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERMEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGA-LEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE-----FARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPA-YSGPGSVPGALDYAAFSSALY 889

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Human
Match: ACTN2 (actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164])

HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0
Identity = 324/888 (36.49%), Postives = 510/888 (57.43%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D   +  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A E FK+T+ EA  E   + ++ + + +++ +  ++    NPY+ + + +++  W ++++ +P RD++L+E L +Q   +  +  F+  +  +      ++ +I +S   +  + +  +  + + ++  +    + +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP   S  G     LDY  FS  L+
Sbjct:   17 DEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERMEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGA-LEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE-----FARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPA-YSGPGSVPGALDYAAFSSALY 889

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Human
Match: ACTN3 (actinin alpha 3 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:165])

HSP 1 Score: 601.282 bits (1549), Expect = 0.000e+0
Identity = 324/880 (36.82%), Postives = 493/880 (56.02%), Query Frame = 1

Query:  202 DKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   +  L+NR      + +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YE+ +  +  R   +Q+    F     +  AW   K ++L  +DY++A L E++ L R  E F S++ +H+ R + I  +A EL  L+Y +  ++  +   I + W+ L  L  +R + +      L  ID LQLEFA+R  P  NW    ++DL D +  HS ++ + L+ A + FK+T+ EA  E   +  +   I +I    GL+    NPY  +  QD+   W  + + +P  D+TL+E L +Q   +  +  F+  +  +      ++ ++ +    +  S   + A   Q  Q  +N   + ++ L+  +Q L E    DN  T YS E         L++I  T+N + N++    +  L+  Q        + E++  F +FDR  +  ++   FR+C++S+GY L E E     F  IM +VDP   G +T  +F+DF+ ++ +    +EQ V SFKILA +++ I    + +ELP   A+YCI  M V    +G     LDY  FS  L+
Sbjct:   32 DWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRIQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFRQKASLHEAWTRGKEEMLSQRDYDSALLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDRLQLEFARRAAPFNNWLDGAVEDLQDVWLVHSVEETQSLLTAHDQFKATLPEADRERGAIMGIQGEIQKICQTYGLRPCSTNPYITLSPQDINTKWDMVRKLVPSCDQTLQEELARQQVNERLRRQFAAQANAIGPWIQAKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIIN-YKTNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQ--------LNEFRASFNHFDRKQNGMMEPDDFRACLISMGYDLGEVE-----FARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTTEQVVASFKILAGDKNYITPEELRRELPAKQAEYCIRRM-VPYKGSGAPAGALDYVAFSSALY 896

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Human
Match: ACTN1 (actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163])

HSP 1 Score: 598.971 bits (1543), Expect = 0.000e+0
Identity = 326/891 (36.59%), Postives = 500/891 (56.12%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            N+Y   + D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + L  P++GKMR HKI+NVNKAL FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ ++NF  S++DGL FCALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D++     DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR   +    +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + + +    F     +  AW   K  +L  KDYETA LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R E +      L  ID L LE+AKR  P  NW +  ++DL D F  H+ ++I+ L  A E FK+T+ +A  E   +  + + + +IV    +     NPYT I  Q++   W  + + +P RD+ L E   +Q   +  +  F   +  +        EE+  I   +   +   ++      + ++  +     ++++L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR +S  L   +F++C++SLGY +  + + + +F  IM +VDP   G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M    +        LDY +FS  L+
Sbjct:   10 NDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLS----HLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARM-APYTGPDSVPGALDYMSFSTALY 887

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Human
Match: ACTN1 (actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163])

HSP 1 Score: 595.119 bits (1533), Expect = 0.000e+0
Identity = 327/891 (36.70%), Postives = 498/891 (55.89%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            N+Y   + D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + L  P++GKMR HKI+NVNKAL FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ ++NF  S++DGL FCALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D++     DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR   +    +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + + +    F     +  AW   K  +L  KDYETA LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R E +      L  ID L LE+AKR  P  NW +  ++DL D F  H+ ++I+ L  A E FK+T+ +A  E   +  + + + +IV    +     NPYT I  Q++   W  + + +P RD+ L E   +Q   +  +  F   +  +        EE+  I   +   +   ++      + ++  +     ++++L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY++ E E     F  IM +VDP   G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M    +        LDY +FS  L+
Sbjct:   10 NDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQVEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLS----HLRQYEKSIVNYKPKIDQLEGDHQLIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAE-----FARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITMDELRRELPPDQAEYCIARM-APYTGPDSVPGALDYMSFSTALY 882

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 602.438 bits (1552), Expect = 0.000e+0
Identity = 326/885 (36.84%), Postives = 506/885 (57.18%), Query Frame = 1

Query:  175 GNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPL-NPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRA------CKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G +Y  ++ + + +  +DP WE QQ  TFTAWCN+HLRKA   ID  E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL++IE KGVKL SIGAEEIVDGNVKMTLG+IWTIILRF IQ+I VE+ SA++GLLLWC+RKT  Y N+ V+NF NS++DGL FCALI  H   LLDY  L      HNL LAF +AEKHLD+P+ML+ +DM  N   DE+++M YVS YYH      K +TA   IC++L    E  +   + + L+ +LL W+  W+  L NRS  D       K+ +++NYR  +KP + +DK ++          + L+ + +   +  ++   + + W  +E  E  +EE +  +  R + +++    F     +   W   K D L S D+ +  L ++K L++  E F S++G+H+ R ++I  IA EL  L Y D+  I  +   I + W+ L  L+ +R E +         +D L L+FAKR  P  NW     +DL D    H   +I++L+ A + FKST+ +A  E + +  +   +  +VT+ GL +  L NPYTD+   D+++ W +++ S+P RD  L+  L +Q   +  +  F++ + ++   L   ++ L  +++  +  R        + ++ Q  +      L+EL+ ++Q++ E+   +N K+ YS E L    ETL   +N+ I++  +  L  +   IS   ++ E++  F +FD+  +  LD  Q RSC++S+GY++    E D +   ++  VDP   G +   +FLDF+ ++NS++   EQ ++SF+ILA+ ++ I    + +ELP   A YC+  M            + DY TFS  L+
Sbjct:   15 GYDYTQQEEEWDREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIDTIEEDFRNGLKLMLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLIWTIILRFAIQDINVEELSARDGLLLWCQRKTAPYNNVNVQNFHNSWKDGLAFCALIHRHRPDLLDYSQLHKGDPIHNLNLAFDIAEKHLDIPKMLDAEDMA-NSQPDEKAVMTYVSCYYHYFSGMRKAETAANRICRVLKVNQENEKMMEDYENLASDLLAWINRWMPWLANRSTDDTLQQAQQKLEDYRNYRRREKPPRIEDKGRLETLFNTLQTRLRLSNRPAFLPRDGHLIKDINAAWAGLEDSEKGFEEWLLSEIMRLERLEHLAEKFRRKCALHEEWAHGKEDALRSNDWRSCGLYKIKALRKRHEAFESDLGAHQDRVEQIAAIARELNNLRYPDIGPINARCQAICSQWDRLGQLSSKRRETLEDAERIAERLDSLYLDFAKRAAPFNNWLDGAREDLADLVIVHEMREIEELVNAHDQFKSTLGDADREFSSINQIEHEVEHLVTSHGLDRELLRNPYTDLSASDIRRKWGEVQNSVPRRDSQLQAELKRQQNNERLRTIFAEKANQVGPWL---ERELEQVLAIGLGGRGRLEDAIQQLRSIQRNVLGYKPNLDELERVHQEMQENFVFENRKSRYSMESLRVGWETLLTSINKTINEFENQVLLRDSKGIS-EEQIAEFRASFSHFDKERAG-LDPEQLRSCLISVGYTIRPGREGDAELHRVLAHVDPNRMGRVPFEAFLDFMTKENSDQDTVEQMIDSFRILASGKTFITADELERELPRDQAAYCMARMAPSREPGAPPRSF-DYVTFSRSLY 892

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 585.489 bits (1508), Expect = 0.000e+0
Identity = 327/912 (35.86%), Postives = 509/912 (55.81%), Query Frame = 1

Query:  175 GNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAI-------------------------ERKEKMD--TALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPL-NPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRA------CKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G +Y  ++ + + +  +DP WE QQ  TFTAWCN+HLRKA   ID  E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL++IE KGVKL SIGAEEIVDGNVKMTLG+IWTIILRF IQ+I VE+ SA++GLLLWC+RKT  Y N+ V+NF NS++DGL FCALI  H   LLDY  L      HNL LAF +AEKHLD+P+ML+ +D+  ++  DE+S M YVS +YHA                          ER  + D  TA   IC++L    E  +   + + L+ +LL W+  W+  L NRS  D       K+ +++NYR  +KP + +DK ++          + L+ + +   +  ++   + + W  +E  E  +EE +  +  R + +++    F     +   W   K D L S D+ +  L ++K L++  E F S++G+H+ R ++I  IA EL  L Y D+  I  +   I + W+ L  L+ +R E +         +D L L+FAKR  P  NW     +DL D    H   +I++L+ A + FKST+ +A  E + +  +   +  +VT+ GL +  L NPYTD+   D+++ W +++ S+P RD  L+  L +Q   +  +  F++ + ++   L   ++ L  +++  +  R        + ++ Q  +      L+EL+ ++Q++ E+   +N K+ YS E L    ETL   +N+ I++  +  L  +   IS   ++ E++  F +FD+  +  LD  Q RSC++S+GY++    E D +   ++  VDP   G +   +FLDF+ ++NS++   EQ ++SF+ILA+ ++ I    + +ELP   A YC+  M            + DY TFS  L+
Sbjct:   15 GYDYTQQEEEWDREGLLDPAWEKQQKKTFTAWCNSHLRKAGTSIDTIEEDFRNGLKLMLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLIWTIILRFAIQDINVEELSARDGLLLWCQRKTAPYNNVNVQNFHNSWKDGLAFCALIHRHRPDLLDYSQLHKGDPIHNLNLAFDIAEKHLDIPKMLDAEDV--SRHPDEKSTMTYVSCFYHAFRNMRDPPPPVIRQPPPQRVVVAPPPERDWRKDAETAANRICRVLKVNQENEKMMEDYENLASDLLAWINRWMPWLANRSTDDTLQQAQQKLEDYRNYRRREKPPRIEDKGRLETLFNTLQTRLRLSNRPAFLPRDGHLIKDINAAWAGLEDSEKGFEEWLLSEIMRLERLEHLAEKFRRKCALHEEWAHGKEDALRSNDWRSCGLYKIKALRKRHEAFESDLGAHQDRVEQIAAIARELNNLRYPDIGPINARCQAICSQWDRLGQLSSKRRETLEDAERIAERLDSLYLDFAKRAAPFNNWLDGAREDLADLVIVHEMREIEELVNAHDQFKSTLGDADREFSSINQIEHEVEHLVTSHGLDRELLRNPYTDLSASDIRRKWGEVQNSVPRRDSQLQAELKRQQNNERLRTIFAEKANQVGPWL---ERELEQVLAIGLGGRGRLEDAIQQLRSIQRNVLGYKPNLDELERVHQEMQENFVFENRKSRYSMESLRVGWETLLTSINKTINEFENQVLLRDSKGIS-EEQIAEFRASFSHFDKERAG-LDPEQLRSCLISVGYTIRPGREGDAELHRVLAHVDPNRMGRVPFEAFLDFMTKENSDQDTVEQMIDSFRILASGKTFITADELERELPRDQAAYCMARMAPSREPGAPPRSF-DYVTFSRSLY 918

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 538.11 bits (1385), Expect = 1.951e-177
Identity = 296/828 (35.75%), Postives = 467/828 (56.40%), Query Frame = 1

Query:  346 MKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPL-NPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRA------CKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            M LLE+IS + LP PD+GKMRFHKIANVNKAL++IE KGVKL SIGAEEIVDGNVKMTLG+IWTIILRF IQ+I VE+ SA++GLLLWC+RKT  Y N+ V+NF NS++DGL FCALI  H   LLDY  L      HNL LAF +AEKHLD+P+ML+ +DM  N   DE+++M YVS YYH      K +TA   IC++L    E  +   + + L+ +LL W+  W+  L NRS  D       K+ +++NYR  +KP + +DK ++          + L+ + +   +  ++   + + W  +E  E  +EE +  +  R + +++    F     +   W   K D L S D+ +  L ++K L++  E F S++G+H+ R ++I  IA EL  L Y D+  I  +   I + W+ L  L+ +R E +         +D L L+FAKR  P  NW     +DL D    H   +I++L+ A + FKST+ +A  E + +  +   +  +VT+ GL +  L NPYTD+   D+++ W +++ S+P RD  L+  L +Q   +  +  F++ + ++   L   ++ L  +++  +  R        + ++ Q  +      L+EL+ ++Q++ E+   +N K+ YS E L    ETL   +N+ I++  +  L  +   IS   ++ E++  F +FD+  +  LD  Q RSC++S+GY++    E D +   ++  VDP   G +   +FLDF+ ++NS++   EQ ++SF+ILA+ ++ I    + +ELP   A YC+  M            + DY TFS  L+
Sbjct:    1 MLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLIWTIILRFAIQDINVEELSARDGLLLWCQRKTAPYNNVNVQNFHNSWKDGLAFCALIHRHRPDLLDYSQLHKGDPIHNLNLAFDIAEKHLDIPKMLDAEDMA-NSQPDEKAVMTYVSCYYHYFSGMRKAETAANRICRVLKVNQENEKMMEDYENLASDLLAWINRWMPWLANRSTDDTLQQAQQKLEDYRNYRRREKPPRIEDKGRLETLFNTLQTRLRLSNRPAFLPRDGHLIKDINAAWAGLEDSEKGFEEWLLSEIMRLERLEHLAEKFRRKCALHEEWAHGKEDALRSNDWRSCGLYKIKALRKRHEAFESDLGAHQDRVEQIAAIARELNNLRYPDIGPINARCQAICSQWDRLGQLSSKRRETLEDAERIAERLDSLYLDFAKRAAPFNNWLDGAREDLADLVIVHEMREIEELVNAHDQFKSTLGDADREFSSINQIEHEVEHLVTSHGLDRELLRNPYTDLSASDIRRKWGEVQNSVPRRDSQLQAELKRQQNNERLRTIFAEKANQVGPWL---ERELEQVLAIGLGGRGRLEDAIQQLRSIQRNVLGYKPNLDELERVHQEMQENFVFENRKSRYSMESLRVGWETLLTSINKTINEFENQVLLRDSKGIS-EEQIAEFRASFSHFDKERAG-LDPEQLRSCLISVGYTIRPGREGDAELHRVLAHVDPNRMGRVPFEAFLDFMTKENSDQDTVEQMIDSFRILASGKTFITADELERELPRDQAAYCMARMAPSREPGAPPRSF-DYVTFSRSLY 821

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Celegans
Match: atn-1 (AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8])

HSP 1 Score: 520.776 bits (1340), Expect = 1.702e-170
Identity = 297/855 (34.74%), Postives = 470/855 (54.97%), Query Frame = 1

Query:  346 MKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAI-------------------------ERKEKMD--TALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPL-NPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRA------CKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            M LLE+IS + LP PD+GKMRFHKIANVNKAL++IE KGVKL SIGAEEIVDGNVKMTLG+IWTIILRF IQ+I VE+ SA++GLLLWC+RKT  Y N+ V+NF NS++DGL FCALI  H   LLDY  L      HNL LAF +AEKHLD+P+ML+ +D+  ++  DE+S M YVS +YHA                          ER  + D  TA   IC++L    E  +   + + L+ +LL W+  W+  L NRS  D       K+ +++NYR  +KP + +DK ++          + L+ + +   +  ++   + + W  +E  E  +EE +  +  R + +++    F     +   W   K D L S D+ +  L ++K L++  E F S++G+H+ R ++I  IA EL  L Y D+  I  +   I + W+ L  L+ +R E +         +D L L+FAKR  P  NW     +DL D    H   +I++L+ A + FKST+ +A  E + +  +   +  +VT+ GL +  L NPYTD+   D+++ W +++ S+P RD  L+  L +Q   +  +  F++ + ++   L   ++ L  +++  +  R        + ++ Q  +      L+EL+ ++Q++ E+   +N K+ YS E L    ETL   +N+ I++  +  L  +   IS   ++ E++  F +FD+  +  LD  Q RSC++S+GY++    E D +   ++  VDP   G +   +FLDF+ ++NS++   EQ ++SF+ILA+ ++ I    + +ELP   A YC+  M            + DY TFS  L+
Sbjct:    1 MLLLEVISGEPLPKPDRGKMRFHKIANVNKALEYIESKGVKLVSIGAEEIVDGNVKMTLGLIWTIILRFAIQDINVEELSARDGLLLWCQRKTAPYNNVNVQNFHNSWKDGLAFCALIHRHRPDLLDYSQLHKGDPIHNLNLAFDIAEKHLDIPKMLDAEDV--SRHPDEKSTMTYVSCFYHAFRNMRDPPPPVIRQPPPQRVVVAPPPERDWRKDAETAANRICRVLKVNQENEKMMEDYENLASDLLAWINRWMPWLANRSTDDTLQQAQQKLEDYRNYRRREKPPRIEDKGRLETLFNTLQTRLRLSNRPAFLPRDGHLIKDINAAWAGLEDSEKGFEEWLLSEIMRLERLEHLAEKFRRKCALHEEWAHGKEDALRSNDWRSCGLYKIKALRKRHEAFESDLGAHQDRVEQIAAIARELNNLRYPDIGPINARCQAICSQWDRLGQLSSKRRETLEDAERIAERLDSLYLDFAKRAAPFNNWLDGAREDLADLVIVHEMREIEELVNAHDQFKSTLGDADREFSSINQIEHEVEHLVTSHGLDRELLRNPYTDLSASDIRRKWGEVQNSVPRRDSQLQAELKRQQNNERLRTIFAEKANQVGPWL---ERELEQVLAIGLGGRGRLEDAIQQLRSIQRNVLGYKPNLDELERVHQEMQENFVFENRKSRYSMESLRVGWETLLTSINKTINEFENQVLLRDSKGIS-EEQIAEFRASFSHFDKERAG-LDPEQLRSCLISVGYTIRPGREGDAELHRVLAHVDPNRMGRVPFEAFLDFMTKENSDQDTVEQMIDSFRILASGKTFITADELERELPRDQAAYCMARMAPSREPGAPPRSF-DYVTFSRSLY 847

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Celegans
Match: unc-70 (Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:E0AHA7])

HSP 1 Score: 271.552 bits (693), Expect = 6.560e-75
Identity = 157/471 (33.33%), Postives = 261/471 (55.41%), Query Frame = 1

Query:  247 QISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDS------SAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEK--NKDKIQIMYLNLK---KSTEKKKF-----NICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERI 1611
            Q  TFT W N+HL + S K+ +   D R G  L++LL ++S + LP P  GKMR H + NV K L+F+  + V L ++G+ +IVDGN ++TLG+IWTIILRF IQ+I  ED+      SAKE LLLWC+ KT GY N+ V+NF  S++DGL F ALI  H   L+DYD+L  S   +NL+ AF  AE  L + + L+ +D ++    DE+SI+ YV +YYH   + ++ +   K I K++++ ME  +     + LS +LL W+   I  L  R   ++   +  +++ F +YR  +KP K   K +++++   L+   ++  ++ F      + + +   W  +EK E+  E  + E+  R + ++     F    +++  W++     LVS+D    +LS ++   +  E   +++ +++ R   +V +A EL+  NY D   I ++   +L  W  L+ L   R  R+
Sbjct:  111 QKKTFTKWVNSHLVRVSCKVQDLYMDMRDGKMLLRLLAVLSGERLPKPTPGKMRIHCLENVEKGLQFLRNQHVHLENLGSHDIVDGNSRLTLGLIWTIILRFQIQDITFEDADNHETRSAKEALLLWCQMKTAGYPNVNVKNFSTSWRDGLAFNALIHKHRPDLVDYDNLQKSNALYNLQSAFDTAENQLGLAKFLDAED-VNVDQPDEKSIITYVVTYYHYFNKLKQDNIQGKRIGKVINELMENDKMINRYETLSSDLLEWINAKIQLLNERHFENNLEGVQRQLTEFNDYRTQEKPPKFDEKGELEVLLFTLQSAMRANNQRPFVPREGKLIADINRAWQSLEKAEHERELVLKEELIRQEKLEQLAARFNRKAEMRETWLTEN-QRLVSQDNFGNDLSSVEAATKKHEAIETDIFAYEERVQAVVAVAGELEAENYHDQAKINERKENVLQLWNYLFQLLLARRVRL 579

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0333801)

HSP 1 Score: 597.045 bits (1538), Expect = 0.000e+0
Identity = 325/868 (37.44%), Postives = 497/868 (57.26%), Query Frame = 1

Query:  223 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA---EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHST 2784
            +DP WE QQ  TFTAWCN+HLRKA   IDN E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL FI  KGV L SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE+ +AKEGLLLWC+RKT  YKN+ V+NF  SF+DGL FCALI  H   L+DY  LS      NL  AF +AEK+LD+P+ML+ DD+I+    DER+IM YVS YYHA +  ++ +TA   ICK+L    E  +     + L+ +LL W+   +  L +R   +    +  K+  ++ YR   KP + + K ++          + L+ + +    +    S + + W  +E  E  +EE +  +  R + +++    F+        W   K ++L S+D+    L+ELK L++  E F S++ +H+ R ++I  IA EL  L Y D  ++  +   I + W+ L  L  +R   ++     L +ID L LEFAKR  P  NW     +DL D F  H+ ++I+ LI+A + FK+T+ EA  E   + +L   +  IV    +     NPYT +   D+ + W  + + +P+RD+TL   L KQ   +  +  F++ +  +    E   D   ++   +  ++  +  + + ++  +      + EL+ I+Q + E    +N  T Y+ E L    E L   +N  I++  +  LT +   IS   ++ E+++ F +FD+  + +L   +F+SC++SLGYS+ ++ + D  F+ I+ +VDP NTG++   +FLDF+ +++++   +EQ ++SF+ILA ++  I    + +ELP   A+YCI+ MP     NG     LDY +FS  L+  T
Sbjct:   28 LDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGIS-QEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGA-LDYMSFSTALYGET 893

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0070343)

HSP 1 Score: 597.045 bits (1538), Expect = 0.000e+0
Identity = 325/868 (37.44%), Postives = 497/868 (57.26%), Query Frame = 1

Query:  223 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA---EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHST 2784
            +DP WE QQ  TFTAWCN+HLRKA   IDN E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL FI  KGV L SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE+ +AKEGLLLWC+RKT  YKN+ V+NF  SF+DGL FCALI  H   L+DY  LS      NL  AF +AEK+LD+P+ML+ DD+I+    DER+IM YVS YYHA +  ++ +TA   ICK+L    E  +     + L+ +LL W+   +  L +R   +    +  K+  ++ YR   KP + + K ++          + L+ + +    +    S + + W  +E  E  +EE +  +  R + +++    F+        W   K ++L S+D+    L+ELK L++  E F S++ +H+ R ++I  IA EL  L Y D  ++  +   I + W+ L  L  +R   ++     L +ID L LEFAKR  P  NW     +DL D F  H+ ++I+ LI+A + FK+T+ EA  E   + +L   +  IV    +     NPYT +   D+ + W  + + +P+RD+TL   L KQ   +  +  F++ +  +    E   D   ++   +  ++  +  + + ++  +      + EL+ I+Q + E    +N  T Y+ E L    E L   +N  I++  +  LT +   IS   ++ E+++ F +FD+  + +L   +F+SC++SLGYS+ ++ + D  F+ I+ +VDP NTG++   +FLDF+ +++++   +EQ ++SF+ILA ++  I    + +ELP   A+YCI+ MP     NG     LDY +FS  L+  T
Sbjct:   28 LDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGIS-QEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGA-LDYMSFSTALYGET 893

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0303048)

HSP 1 Score: 597.045 bits (1538), Expect = 0.000e+0
Identity = 325/868 (37.44%), Postives = 497/868 (57.26%), Query Frame = 1

Query:  223 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA---EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHST 2784
            +DP WE QQ  TFTAWCN+HLRKA   IDN E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL FI  KGV L SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE+ +AKEGLLLWC+RKT  YKN+ V+NF  SF+DGL FCALI  H   L+DY  LS      NL  AF +AEK+LD+P+ML+ DD+I+    DER+IM YVS YYHA +  ++ +TA   ICK+L    E  +     + L+ +LL W+   +  L +R   +    +  K+  ++ YR   KP + + K ++          + L+ + +    +    S + + W  +E  E  +EE +  +  R + +++    F+        W   K ++L S+D+    L+ELK L++  E F S++ +H+ R ++I  IA EL  L Y D  ++  +   I + W+ L  L  +R   ++     L +ID L LEFAKR  P  NW     +DL D F  H+ ++I+ LI+A + FK+T+ EA  E   + +L   +  IV    +     NPYT +   D+ + W  + + +P+RD+TL   L KQ   +  +  F++ +  +    E   D   ++   +  ++  +  + + ++  +      + EL+ I+Q + E    +N  T Y+ E L    E L   +N  I++  +  LT +   IS   ++ E+++ F +FD+  + +L   +F+SC++SLGYS+ ++ + D  F+ I+ +VDP NTG++   +FLDF+ +++++   +EQ ++SF+ILA ++  I    + +ELP   A+YCI+ MP     NG     LDY +FS  L+  T
Sbjct:   28 LDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGIS-QEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGA-LDYMSFSTALYGET 893

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0070344)

HSP 1 Score: 592.808 bits (1527), Expect = 0.000e+0
Identity = 324/868 (37.33%), Postives = 495/868 (57.03%), Query Frame = 1

Query:  223 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA---EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHST 2784
            +DP WE QQ  TFTAWCN+HLRKA   IDN E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL FI  KGV L SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE+ +AKEGLLLWC+RKT  YKN+ V+NF  SF+DGL FCALI  H   L+DY  LS      NL  AF +AEK+LD+P+ML+ DD+ +    DER++M YVSSYYH     +K +TA   ICK+L    E  +     + L+ +LL W+   +  L +R   +    +  K+  ++ YR   KP + + K ++          + L+ + +    +    S + + W  +E  E  +EE +  +  R + +++    F+        W   K ++L S+D+    L+ELK L++  E F S++ +H+ R ++I  IA EL  L Y D  ++  +   I + W+ L  L  +R   ++     L +ID L LEFAKR  P  NW     +DL D F  H+ ++I+ LI+A + FK+T+ EA  E   + +L   +  IV    +     NPYT +   D+ + W  + + +P+RD+TL   L KQ   +  +  F++ +  +    E   D   ++   +  ++  +  + + ++  +      + EL+ I+Q + E    +N  T Y+ E L    E L   +N  I++  +  LT +   IS   ++ E+++ F +FD+  + +L   +F+SC++SLGYS+ ++ + D  F+ I+ +VDP NTG++   +FLDF+ +++++   +EQ ++SF+ILA ++  I    + +ELP   A+YCI+ MP     NG     LDY +FS  L+  T
Sbjct:   28 LDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLQNTALPDERAVMTYVSSYYHCFSGAQKAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGIS-QEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGA-LDYMSFSTALYGET 893

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BLAST of Actinin alpha 4 vs. Ensembl Fly
Match: Actn (gene:FBgn0000667 transcript:FBtr0310657)

HSP 1 Score: 588.571 bits (1516), Expect = 0.000e+0
Identity = 324/870 (37.24%), Postives = 495/870 (56.90%), Query Frame = 1

Query:  223 IDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAEL--KRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA---EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNE-ISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHST 2784
            +DP WE QQ  TFTAWCN+HLRKA   IDN E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL FI  KGV L SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE+ +AKEGLLLWC+RKT  YKN+ V+NF  SF+DGL FCALI  H   L+DY  LS      NL  AF +AEK+LD+P+ML+ DD+ +    DER++M YVSSYYH     +K +TA   ICK+L    E  +     + L+ +LL W+   +  L +R   +    +  K+  ++ YR   KP + + K ++          + L+ + +    +    S + + W  +E  E  +EE +  +  R + +++    F+        W   K ++L S+D+    L+ELK L++  E F S++ +H+ R ++I  IA EL    L Y D  ++  +   I + W+ L  L  +R   ++     L +ID L LEFAKR  P  NW     +DL D F  H+ ++I+ LI+A + FK+T+ EA  E   + +L   +  IV    +     NPYT +   D+ + W  + + +P+RD+TL   L KQ   +  +  F++ +  +    E   D   ++   +  ++  +  + + ++  +      + EL+ I+Q + E    +N  T Y+ E L    E L   +N  I++  +  LT +   IS   ++ E+++ F +FD+  + +L   +F+SC++SLGYS+ ++ + D  F+ I+ +VDP NTG++   +FLDF+ +++++   +EQ ++SF+ILA ++  I    + +ELP   A+YCI+ MP     NG     LDY +FS  L+  T
Sbjct:   28 LDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLQNTALPDERAVMTYVSSYYHCFSGAQKAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNVSTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGIS-QEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGA-LDYMSFSTALYGET 895

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BLAST of Actinin alpha 4 vs. Ensembl Zebrafish
Match: actn4 (actinin, alpha 4 [Source:ZFIN;Acc:ZDB-GENE-030131-940])

HSP 1 Score: 619.002 bits (1595), Expect = 0.000e+0
Identity = 332/886 (37.47%), Postives = 510/886 (57.56%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDM---MSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHE----TLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYD L       NL  AF +AE++LD+P+ML+ +D+++    DE++IM YVSS+YHA    +K +TA   ICK+L+   E      + + L+ +LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S +   W+++E  E  YEE +  +  R + + +    F     +   W   K  +L  KDYETA+LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I   W+ L  L   R E +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ D+I+ LI A E FKST+ EA  E   ++++   + +I    G++    NPYT I  Q + K W ++++ +P+RD+ L+E L +Q      +  F+  +  +   + +  + +  +   M+  +  +      ++  + +    +++L+  +Q + E    DN  T Y+ E L    E    T+   +NEI       LT +   IS   ++ EY+T F +FD+ +S  L   +F++C++SLGY ++ +++ D +F  IM +VDP N+G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M    S        LDY +FS  L+
Sbjct:   16 GGPPTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIDYDKLRKDDPVTNLNNAFEVAERYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLENRAPEKTMAEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINGAWHKLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEGWTDGKEAMLTQKDYETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICEQWDALGSLTQNRRESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIDEIQGLITAHEQFKSTLPEANKEREAIQAIQAEVQKIANYNGIKLAGNNPYTTITPQSIDKKWEKVQQLVPQRDQALQEELTRQQSNDHLRRQFANQANMIGPWIQNKMEEIGRISIEMNGTLEDQLTHLSQYEQSIIEYKPNIDQLEGDHQLIQEALIFDNKYTAYTMEHLRVGWEQLLTTIARTINEIENQV---LTRDAKGIS-QEQLHEYRTSFNHFDKDHSGLLQSEEFKACLISLGYDVENDKQGDAEFARIMGIVDPNNSGAVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNYITAEELRRELPPDQAEYCIARM-APYSGPDAVAGALDYMSFSTALY 896

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Zebrafish
Match: actn4 (actinin, alpha 4 [Source:ZFIN;Acc:ZDB-GENE-030131-940])

HSP 1 Score: 615.92 bits (1587), Expect = 0.000e+0
Identity = 331/886 (37.36%), Postives = 508/886 (57.34%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDM---MSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHE----TLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYD L       NL  AF +AE++LD+P+ML+ +D++     DE++IM YVS +YHA    +K +TA   ICK+L+   E      + + L+ +LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S +   W+++E  E  YEE +  +  R + + +    F     +   W   K  +L  KDYETA+LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I   W+ L  L   R E +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ D+I+ LI A E FKST+ EA  E   ++++   + +I    G++    NPYT I  Q + K W ++++ +P+RD+ L+E L +Q      +  F+  +  +   + +  + +  +   M+  +  +      ++  + +    +++L+  +Q + E    DN  T Y+ E L    E    T+   +NEI       LT +   IS   ++ EY+T F +FD+ +S  L   +F++C++SLGY ++ +++ D +F  IM +VDP N+G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M    S        LDY +FS  L+
Sbjct:   16 GGPPTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIDYDKLRKDDPVTNLNNAFEVAERYLDIPKMLDAEDIVGTLRPDEKAIMTYVSCFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLENRAPEKTMAEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINGAWHKLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEGWTDGKEAMLTQKDYETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICEQWDALGSLTQNRRESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIDEIQGLITAHEQFKSTLPEANKEREAIQAIQAEVQKIANYNGIKLAGNNPYTTITPQSIDKKWEKVQQLVPQRDQALQEELTRQQSNDHLRRQFANQANMIGPWIQNKMEEIGRISIEMNGTLEDQLTHLSQYEQSIIEYKPNIDQLEGDHQLIQEALIFDNKYTAYTMEHLRVGWEQLLTTIARTINEIENQV---LTRDAKGIS-QEQLHEYRTSFNHFDKDHSGLLQSEEFKACLISLGYDVENDKQGDAEFARIMGIVDPNNSGAVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNYITAEELRRELPPDQAEYCIARM-APYSGPDAVAGALDYMSFSTALY 896

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Zebrafish
Match: actn3a (actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-9])

HSP 1 Score: 615.15 bits (1585), Expect = 0.000e+0
Identity = 343/894 (38.37%), Postives = 510/894 (57.05%), Query Frame = 1

Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            EY  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK LD+P+ML+ DD+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W++  I  L+NR        +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + + +    F     + ++W + K +LL  KDYETA+L E++ L R  E F S++ +H+ R ++I  IA EL  L++ D  TI  +   I + W+ L  L  +R E +         ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A + FK+T+ EA  E   +  +   + +I    G++ +  NPYT +  Q++   W  +++ +P RD+ L+E + +Q   +  +  F+  +  +        EE+S    DI  SL + MS+         +T++  +    S +++L+  +Q   E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA++++ I    + +ELP   A+YCI  M   +  +      LDY +FS  L+
Sbjct:   20 EYMIQEDDWDRDLFLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDIAEKFLDIPKMLDADDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIQRTIPWLENRVAEQTMHAMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLTEIRRLERLDHLAEKFRQKSTLHQSWTTGKEELLSQKDYETASLMEIRALMRKHEAFESDLAAHQDRVEQIAAIAQELNELDFYDAATINAQCQGICDQWDNLGTLTQKRRESLERVEKLWETIDQLYLEFAKRAAPFNNWMDGAMEDLQDMFIVHSIEEIQSLITAHDQFKATLPEADKERMAIMGIHSEVLKIAQTYGIKIVSENPYTVLSHQNIVNKWEAVKQLVPMRDQMLQEEVARQQSNERLRRQFAAQANIIGPWIQTKMEEISHVSIDIAGSLEEQMSN--------LKTYEQNIINYKSNIDKLEGDHQLSQEGLIFDNKHTNYTMEHVRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKAYITVEELRRELPPEQAEYCISRMTKYMGGDAPPGA-LDYISFSSALY 891

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Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            EY  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK LD+P+ML+ DD+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W++  I  L+NR        +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + + +    F     + ++W + K +LL  KDYETA+L E++ L R  E F S++ +H+ R ++I  IA EL  L++ D  TI  +   I + W+ L  L  +R E +         ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A + FK+T+ EA  E   +  +   + +I    G++ +  NPYT +  Q++   W  +++ +P RD+ L+E + +Q   +  +  F+  +  +        EE+S    DI  SL + MS+         +T++  +    S +++L+  +Q   E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA++++ I    + +ELP   A+YCI  M   +  +      LDY +FS  L+
Sbjct:    9 EYMIQEDDWDRDLFLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDIAEKFLDIPKMLDADDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIQRTIPWLENRVAEQTMHAMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLTEIRRLERLDHLAEKFRQKSTLHQSWTTGKEELLSQKDYETASLMEIRALMRKHEAFESDLAAHQDRVEQIAAIAQELNELDFYDAATINAQCQGICDQWDNLGTLTQKRRESLERVEKLWETIDQLYLEFAKRAAPFNNWMDGAMEDLQDMFIVHSIEEIQSLITAHDQFKATLPEADKERMAIMGIHSEVLKIAQTYGIKIVSENPYTVLSHQNIVNKWEAVKQLVPMRDQMLQEEVARQQSNERLRRQFAAQANIIGPWIQTKMEEISHVSIDIAGSLEEQMSN--------LKTYEQNIINYKSNIDKLEGDHQLSQEGLIFDNKHTNYTMEHVRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKAYITVEELRRELPPEQAEYCISRMTKYMGGDAPPGA-LDYISFSSALY 880

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Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            EY  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK LD+P+ML+ DD+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W++  I  L+NR        +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + + +    F     + ++W + K +LL  KDYETA+L E++ L R  E F S++ +H+ R ++I  IA EL  L++ D  TI  +   I + W+ L  L  +R E +         ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A + FK+T+ EA  E   +  +   + +I    G++ +  NPYT +  Q++   W  +++ +P RD+ L+E + +Q   +  +  F+  +  +        EE+S    DI  SL + MS+         +T++  +    S +++L+  +Q   E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA++++ I    + +ELP   A+YCI  M   +  +      LDY +FS  L+
Sbjct:   20 EYMIQEDDWDRDLFLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDIAEKFLDIPKMLDADDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIQRTIPWLENRVAEQTMHAMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLTEIRRLERLDHLAEKFRQKSTLHQSWTTGKEELLSQKDYETASLMEIRALMRKHEAFESDLAAHQDRVEQIAAIAQELNELDFYDAATINAQCQGICDQWDNLGTLTQKRRESLERVEKLWETIDQLYLEFAKRAAPFNNWMDGAMEDLQDMFIVHSIEEIQSLITAHDQFKATLPEADKERMAIMGIHSEVLKIAQTYGIKIVSENPYTVLSHQNIVNKWEAVKQLVPMRDQMLQEEVARQQSNERLRRQFAAQANIIGPWIQTKMEEISHVSIDIAGSLEEQMSN--------LKTYEQNIINYKSNIDKLEGDHQLSQEGLIFDNKHTNYTMEHVRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKAYITVEELRRELPPEQAEYCISRMTKYMGGDAPPGA-LDYISFSSALY 891

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BLAST of Actinin alpha 4 vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 624.009 bits (1608), Expect = 0.000e+0
Identity = 344/899 (38.26%), Postives = 515/899 (57.29%), Query Frame = 1

Query:  166 EGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            EG+  +Y  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+   +   +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W   K +LL  +DYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R + +      L  ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A E FK+T+ EA  E   +  +   I +I    G++   +NPYT++   D+   W  +++ +P RD+TL+E L +Q   +  +  F+  +  +        EE+     DI  SL D M+          + ++  +    S +++L+  +Q + E    DN  T YS E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA+++S I    + +ELP   A+YCI  M  K +        LDY +FS  L+
Sbjct:   25 EGIPEDYMVQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRTPEKNMGAMQKKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLLEIRRLERLEHLAEKFKQKASLHESWTRGKEELLTQRDYESASLMEIRALVRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNSRCQAICDQWDNLGTLTQKRRDALERVEKLLETIDQLYLEFAKRAAPFNNWMDGAVEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADKEKMSILGIQAEIQKIAQTYGIKLSGINPYTNLTHLDISNKWETVKQLVPHRDQTLQEELARQQANERLRRQFAAQANVIGPWIQSKMEEIGRISVDISASLEDQMNH--------LKQYEQNIISYKSNIDKLEGDHQLIQESLIFDNKHTNYSMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKSYITIEELRRELPPEQAEYCITRM-TKYTGADAISGALDYMSFSSALY 901

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 620.157 bits (1598), Expect = 0.000e+0
Identity = 342/897 (38.13%), Postives = 513/897 (57.19%), Query Frame = 1

Query:  172 LGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +  +Y  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+   +   +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W   K +LL  +DYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R + +      L  ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A E FK+T+ EA  E   +  +   I +I    G++   +NPYT++   D+   W  +++ +P RD+TL+E L +Q   +  +  F+  +  +        EE+     DI  SL D M+          + ++  +    S +++L+  +Q + E    DN  T YS E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA+++S I    + +ELP   A+YCI  M  K +        LDY +FS  L+
Sbjct:   23 MDEDYMVQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRTPEKNMGAMQKKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLLEIRRLERLEHLAEKFKQKASLHESWTRGKEELLTQRDYESASLMEIRALVRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNSRCQAICDQWDNLGTLTQKRRDALERVEKLLETIDQLYLEFAKRAAPFNNWMDGAVEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADKEKMSILGIQAEIQKIAQTYGIKLSGINPYTNLTHLDISNKWETVKQLVPHRDQTLQEELARQQANERLRRQFAAQANVIGPWIQSKMEEIGRISVDISASLEDQMNH--------LKQYEQNIISYKSNIDKLEGDHQLIQESLIFDNKHTNYSMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKSYITIEELRRELPPEQAEYCITRM-TKYTGADAISGALDYMSFSSALY 897

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 612.838 bits (1579), Expect = 0.000e+0
Identity = 342/900 (38.00%), Postives = 512/900 (56.89%), Query Frame = 1

Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDR------TNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +Y  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+   +   +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W   K +LL  +DYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R + +      L  ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A E FK+T+ EA  E   +  +   I +I    G++   +NPYT++   D+   W  +++ +P RD+TL+E L +Q   +  +  F+  +  +        EE+     DI  SL D M+          + ++  +    S +++L+  +Q + E    DN  T YS E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR        +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA+++S I    + +ELP   A+YCI  M  K +        LDY +FS  L+
Sbjct:   20 DYMVQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRTPEKNMGAMQKKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLLEIRRLERLEHLAEKFKQKASLHESWTRGKEELLTQRDYESASLMEIRALVRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNSRCQAICDQWDNLGTLTQKRRDALERVEKLLETIDQLYLEFAKRAAPFNNWMDGAVEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADKEKMSILGIQAEIQKIAQTYGIKLSGINPYTNLTHLDISNKWETVKQLVPHRDQTLQEELARQQANERLRRQFAAQANVIGPWIQSKMEEIGRISVDISASLEDQMNH--------LKQYEQNIISYKSNIDKLEGDHQLIQESLIFDNKHTNYSMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRLLYDVPKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKSYITIEELRRELPPEQAEYCITRM-TKYTGADAISGALDYMSFSSALY 897

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BLAST of Actinin alpha 4 vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 598.971 bits (1543), Expect = 0.000e+0
Identity = 333/869 (38.32%), Postives = 497/869 (57.19%), Query Frame = 1

Query:  256 TFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+   +   +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W   K +LL  +DYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R + +      L  ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A E FK+T+ EA  E   +  +   I +I    G++   +NPYT++   D+   W  +++ +P RD+TL+E L +Q   +  +  F+  +  +        EE+     DI  SL D M+          + ++  +    S +++L+  +Q + E    DN  T YS E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA+++S I    + +ELP   A+YCI  M  K +        LDY +FS  L+
Sbjct:   59 TFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRTPEKNMGAMQKKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLLEIRRLERLEHLAEKFKQKASLHESWTRGKEELLTQRDYESASLMEIRALVRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNSRCQAICDQWDNLGTLTQKRRDALERVEKLLETIDQLYLEFAKRAAPFNNWMDGAVEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADKEKMSILGIQAEIQKIAQTYGIKLSGINPYTNLTHLDISNKWETVKQLVPHRDQTLQEELARQQANERLRRQFAAQANVIGPWIQSKMEEIGRISVDISASLEDQMNH--------LKQYEQNIISYKSNIDKLEGDHQLIQESLIFDNKHTNYSMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKSYITIEELRRELPPEQAEYCITRM-TKYTGADAISGALDYMSFSSALY 905

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BLAST of Actinin alpha 4 vs. Ensembl Xenopus
Match: gss (glutathione synthetase [Source:Xenbase;Acc:XB-GENE-976512])

HSP 1 Score: 598.586 bits (1542), Expect = 0.000e+0
Identity = 337/894 (37.70%), Postives = 503/894 (56.26%), Query Frame = 1

Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +Y  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  +          S  DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+   +   +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W   K +LL  +DYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R + +      L  ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A E FK+T+ EA  E   +  +   I +I    G++   +NPYT++   D+   W  +++ +P RD+TL+E L +Q   +  +  F+  +  +        EE+     DI  SL D M+          + ++  +    S +++L+  +Q + E    DN  T YS E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA+++S I    + +ELP   A+YCI  M  K +        LDY +FS  L+
Sbjct:   20 DYMVQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTTFH----------SGNDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFDVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRTPEKNMGAMQKKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLLEIRRLERLEHLAEKFKQKASLHESWTRGKEELLTQRDYESASLMEIRALVRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNSRCQAICDQWDNLGTLTQKRRDALERVEKLLETIDQLYLEFAKRAAPFNNWMDGAVEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADKEKMSILGIQAEIQKIAQTYGIKLSGINPYTNLTHLDISNKWETVKQLVPHRDQTLQEELARQQANERLRRQFAAQANVIGPWIQSKMEEIGRISVDISASLEDQMN--------HLKQYEQNIISYKSNIDKLEGDHQLIQESLIFDNKHTNYSMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKSYITIEELRRELPPEQAEYCITRM-TKYTGADAISGALDYMSFSSALY 881

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BLAST of Actinin alpha 4 vs. Ensembl Mouse
Match: Actn3 (actinin alpha 3 [Source:MGI Symbol;Acc:MGI:99678])

HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0
Identity = 339/910 (37.25%), Postives = 508/910 (55.82%), Query Frame = 1

Query:  148 MAIMDFEGLG-----------NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENM-PVKISSNGDNECYLDYCTFSEKLF 2775
            M +M  EGLG            EY +++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   +  L+NR      + +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YE+ +  +  R   +Q+    F+    +  AW   K ++L   DYE+A+L E++ L R  E F S++ +H+ R + I  +A EL  L+Y +  ++  +   I + W+ L  L  +R + +      L  ID LQLEFA+R  P  NW    I+DL D +  HS ++ + L+ A E FK+T+ EA  E   +  +   I +I    GL+    NPY  +  QD+   W  + + +P RD+TL+E L +Q   +  +  F+  +  +      ++ ++ +    +  S   + A   Q  Q  +N   S ++ L+  +Q L E    DN  T YS E         L++I  T+N + N++    +  L+  Q        + E++  F +FDR  +  ++   FR+C++S+GY L E E     F  IM +VDP   G +T  +F+DF+ ++ +    +EQ V SFKILA +++ I    + +ELP   A+YCI  M P K S  G     LDY  FS  L+
Sbjct:    2 MMVMQPEGLGAGEGPFSGGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIIN-YKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQ--------LNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVE-----FARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGS--GAPSGALDYVAFSSALY 895

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BLAST of Actinin alpha 4 vs. Ensembl Mouse
Match: Actn2 (actinin alpha 2 [Source:MGI Symbol;Acc:MGI:109192])

HSP 1 Score: 612.068 bits (1577), Expect = 0.000e+0
Identity = 324/888 (36.49%), Postives = 510/888 (57.43%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D   +  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A E FK+T+ EA  E   + ++ + + +++ +  ++    NPY+ + + +++  W ++++ +P RD++L+E L +Q   +  +  F+  +  +      ++ +I +S   +  + +  +  + + ++  +    + +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP   S  G     LDY  FS  L+
Sbjct:   17 DEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGA-LEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE-----FARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMP-PYSGPGSVPGALDYTAFSSALY 889

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Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D   +  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A E FK+T+ EA  E   + ++ + + +++ +  ++    NPY+ + + +++  W ++++ +P RD++L+E L +Q   +  +  F+  +  +      ++ +I +S   +  + +  +  + + ++  +    + +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP   S  G     LDY  FS  L+
Sbjct:   17 DEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGA-LEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE-----FARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMP-PYSGPGSVPGALDYTAFSSALY 889

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BLAST of Actinin alpha 4 vs. Ensembl Mouse
Match: Actn1 (actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706])

HSP 1 Score: 594.734 bits (1532), Expect = 0.000e+0
Identity = 325/891 (36.48%), Postives = 498/891 (55.89%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            N+Y   + D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + L  P++GKMR HKI+NVNKAL FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ ++NF  S++DGL FCALI  H   L+DY  L       NL  AF +AE+ LD+P+ML+ +D++     DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR   +    +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E+ E  YEE +  +  R + + +    F     +  AW   K  +L  KDYETA LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R E +      L  ID L LE+AKR  P  NW +  ++DL D F  H+ ++I+ L  A E FK+T+ +A  E   +  + + + +IV    +     NPYT I  Q++   W  + + +P RD+ L E   +Q   +  +  F   +  +        EE+  I   +   +   ++      + ++  +     ++++L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR +S  L   +F++C++SLGY +  + + + +F  IM +VDP   G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M    +        LDY +FS  L+
Sbjct:   10 NDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLS----HLRQYEKSIVNYKPKIDQLECDHQLIQEALIFDNKHTNYNMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITEDELRRELPPDQAEYCIARM-APYAGPDSVPGALDYMSFSTALY 887

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BLAST of Actinin alpha 4 vs. Ensembl Mouse
Match: Actn1 (actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:2137706])

HSP 1 Score: 590.882 bits (1522), Expect = 0.000e+0
Identity = 326/891 (36.59%), Postives = 496/891 (55.67%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            N+Y   + D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + L  P++GKMR HKI+NVNKAL FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ ++NF  S++DGL FCALI  H   L+DY  L       NL  AF +AE+ LD+P+ML+ +D++     DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR   +    +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E+ E  YEE +  +  R + + +    F     +  AW   K  +L  KDYETA LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R E +      L  ID L LE+AKR  P  NW +  ++DL D F  H+ ++I+ L  A E FK+T+ +A  E   +  + + + +IV    +     NPYT I  Q++   W  + + +P RD+ L E   +Q   +  +  F   +  +        EE+  I   +   +   ++      + ++  +     ++++L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY++ E E     F  IM +VDP   G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M    +        LDY +FS  L+
Sbjct:   10 NDYMQPEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAFDVAERFLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINNAWGCLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKASIHEAWTDGKEAMLRQKDYETATLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDNLGALTQKRREALERTEKLLETIDQLYLEYAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLTTAHEQFKATLPDADKERLAILGIHNEVSKIVQTYHVNMAGTNPYTTITPQEINGKWDHVRQLVPRRDQALTEEHARQQHNERLRKQFGAQANVIGPWIQTKMEEIGRISIEMHGTLEDQLS----HLRQYEKSIVNYKPKIDQLECDHQLIQEALIFDNKHTNYNMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKKTGMMDTDDFRACLISMGYNMGEAE-----FARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKNYITEDELRRELPPDQAEYCIARM-APYAGPDSVPGALDYMSFSTALY 882

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BLAST of Actinin alpha 4 vs. UniProt/SwissProt
Match: sp|Q0III9|ACTN3_BOVIN (Alpha-actinin-3 OS=Bos taurus OX=9913 GN=ACTN3 PE=2 SV=1)

HSP 1 Score: 619.387 bits (1596), Expect = 0.000e+0
Identity = 337/911 (36.99%), Postives = 506/911 (55.54%), Query Frame = 1

Query:  148 MAIMDFEGLGN------------EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENM-PVKISSNGDNECYLDYCTFSEKLF 2775
            M ++  EGLG             EY +++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   +  L+NR      + +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E+ E  YE+ +  +  R   +Q+    F+    +  AW   K D+L  +DYETA+L E++ L R  E F S++ +H+ R + I  +A EL  L+Y +  ++  +   I + W+ L  L  +R + +      L  ID LQLEFA+R  P  NW    ++DL D +  HS ++ + L+ A + FK+T+ EA  E   +  +   I +I    GL+    NPY  +  QD+   W  + + +P RD+ L+E L +Q   +  +  F+  +  +      ++ ++ +    M  S   + A   Q  Q  +N   S ++ L+  +Q L E    DN  T YS E         L++I  T+N + N++    +  L+  Q        + E++  F +FDR  +  ++   FR+C++S+GY L E E     F  IM +VDP   G +T  +F+DF+ ++ +    +EQ V SFKILA +++ I    + +ELP   A+YCI  M P K    G     LDY  FS  L+
Sbjct:    2 MMVLQPEGLGTGEGPFAGGRGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQAEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEDMLSQRDYETASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAVEDLQDVWLVHSVEETQSLVTAHDQFKATLPEADRERGAILGIQGEIQKICQTYGLRPSSTNPYITLTPQDINTKWDTVRKLVPSRDQMLQEELTRQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGMAGSLEEQMAGLRQQEQNIIN-YKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQ--------LNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVE-----FARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITAEELRRELPAEQAEYCIRRMAPYK--GAGAPAGALDYVAFSSALY 896

[Close]

BLAST of Actinin alpha 4 vs. UniProt/SwissProt
Match: sp|O88990|ACTN3_MOUSE (Alpha-actinin-3 OS=Mus musculus OX=10090 GN=Actn3 PE=2 SV=1)

HSP 1 Score: 618.616 bits (1594), Expect = 0.000e+0
Identity = 339/910 (37.25%), Postives = 508/910 (55.82%), Query Frame = 1

Query:  148 MAIMDFEGLG-----------NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENM-PVKISSNGDNECYLDYCTFSEKLF 2775
            M +M  EGLG            EY +++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   +  L+NR      + +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YE+ +  +  R   +Q+    F+    +  AW   K ++L   DYE+A+L E++ L R  E F S++ +H+ R + I  +A EL  L+Y +  ++  +   I + W+ L  L  +R + +      L  ID LQLEFA+R  P  NW    I+DL D +  HS ++ + L+ A E FK+T+ EA  E   +  +   I +I    GL+    NPY  +  QD+   W  + + +P RD+TL+E L +Q   +  +  F+  +  +      ++ ++ +    +  S   + A   Q  Q  +N   S ++ L+  +Q L E    DN  T YS E         L++I  T+N + N++    +  L+  Q        + E++  F +FDR  +  ++   FR+C++S+GY L E E     F  IM +VDP   G +T  +F+DF+ ++ +    +EQ V SFKILA +++ I    + +ELP   A+YCI  M P K S  G     LDY  FS  L+
Sbjct:    2 MMVMQPEGLGAGEGPFSGGGGGEYMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPRPDKGKMRFHKIANVNKALDFIASKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTVPWLENRVGEPSMSAMQRKLEDFRDYRRLHKPPRVQEKCQLEINFNTLQTKLRLSHRPAFMPSEGKLVSDIANAWRGLEQVEKGYEDWLLSEIRRLQRLQHLAEKFQQKASLHEAWTRGKEEMLNQHDYESASLQEVRALLRRHEAFESDLAAHQDRVEHIAALAQELNELDYHEAASVNSRCQAICDQWDNLGTLTQKRRDALERMEKLLETIDQLQLEFARRAAPFNNWLDGAIEDLQDVWLVHSVEETQSLLTAHEQFKATLPEADRERGAILGIQGEIQKICQTYGLRPKSGNPYITLSSQDINNKWDTVRKLVPSRDQTLQEELARQQVNERLRRQFAAQANAIGPWIQGKVEEVGRLAAGLAGSLEEQMAGLRQQEQNIIN-YKSNIDRLEGDHQLLQESLVFDNKHTVYSMEHIRVGWEQLLTSIARTINEVENQVLTRDAKGLSQEQ--------LNEFRASFNHFDRKRNGMMEPDDFRACLISMGYDLGEVE-----FARIMTMVDPNAAGVVTFQAFIDFMTRETAETDTAEQVVASFKILAGDKNYITPEELRRELPAEQAEYCIRRMAPYKGS--GAPSGALDYVAFSSALY 895

[Close]

BLAST of Actinin alpha 4 vs. UniProt/SwissProt
Match: sp|P20111|ACTN2_CHICK (Alpha-actinin-2 OS=Gallus gallus OX=9031 GN=ACTN2 PE=2 SV=1)

HSP 1 Score: 615.535 bits (1586), Expect = 0.000e+0
Identity = 322/888 (36.26%), Postives = 516/888 (58.11%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ + R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W++L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A + FK+T+ EA  E   + S+ + + +++ +  ++    NPY+ + +++++  W ++++ +P+RD++L+E L +Q   +  +  F+  +  +      ++ +I +S  + M+  +  +  + + ++  +      +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + +++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP + +  G     LDY +FS  L+
Sbjct:   20 DEYMTQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHLSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHEQWAYGKEQILLQKDYESASLTEVRAMLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNDRCQKICDQWDSLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLISAHDQFKATLPEADGERQAILSIQNEVEKVIQSYSMRISASNPYSTVTVEEIRTKWEKVKQLVPQRDQSLQEELARQHANERLRRQFAAQANVIGPWIQTKMEEIARSSIE-MTGPLEDQMNQLKQYEQNIINYKHNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNDFRASFNHFDRRKNGLMDHDDFRACLISMGYDLGEAE-----FARIMSLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILADELRRELPPEQAQYCIKRMP-QYTGPGSVPGALDYTSFSSALY 892

[Close]

BLAST of Actinin alpha 4 vs. UniProt/SwissProt
Match: sp|P35609|ACTN2_HUMAN (Alpha-actinin-2 OS=Homo sapiens OX=9606 GN=ACTN2 PE=1 SV=1)

HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0
Identity = 324/888 (36.49%), Postives = 510/888 (57.43%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D   +  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A E FK+T+ EA  E   + ++ + + +++ +  ++    NPY+ + + +++  W ++++ +P RD++L+E L +Q   +  +  F+  +  +      ++ +I +S   +  + +  +  + + ++  +    + +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP   S  G     LDY  FS  L+
Sbjct:   17 DEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERMEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYSTVTMDELRTKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGA-LEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE-----FARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPA-YSGPGSVPGALDYAAFSSALY 889

[Close]

BLAST of Actinin alpha 4 vs. UniProt/SwissProt
Match: sp|Q9JI91|ACTN2_MOUSE (Alpha-actinin-2 OS=Mus musculus OX=10090 GN=Actn2 PE=1 SV=2)

HSP 1 Score: 612.068 bits (1577), Expect = 0.000e+0
Identity = 324/888 (36.49%), Postives = 510/888 (57.43%), Query Frame = 1

Query:  178 NEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAE----ELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL +I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ ++NF  S++DGL  CALI  H   L+DY  L+      N+ LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S +   W  +E+ E  YEE +  +  R + +++    F         W   K  +L+ KDYE+A+L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D   +  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I+ LI A E FK+T+ EA  E   + ++ + + +++ +  ++    NPY+ + + +++  W ++++ +P RD++L+E L +Q   +  +  F+  +  +      ++ +I +S   +  + +  +  + + ++  +    + +++L+  +Q + E    DN  T Y+ E         L+ I  T+N +  +I    +  +T  Q        + E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ ++   +EQ + SF+ILA+++  I    + +ELP   A+YCI+ MP   S  G     LDY  FS  L+
Sbjct:   17 DEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRTIPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERLEHLAEKFRQKASTHETWAYGKEQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVNDRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQDMFIVHSIEEIQSLITAHEQFKATLPEADGERQSILAIQNEVEKVIQSYSIRISSSNPYSTVTMDELRNKWDKVKQLVPVRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEIARSSIQITGA-LEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHIRVGWELLLTTIARTINEVETQILTRDAKGITQEQ--------MNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAE-----FARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKPYILAEELRRELPPDQAQYCIKRMP-PYSGPGSVPGALDYTAFSSALY 889

[Close]

BLAST of Actinin alpha 4 vs. TrEMBL
Match: A0A3Q2DD20 (Actinin alpha 4 OS=Cyprinodon variegatus OX=28743 GN=ACTN4 PE=4 SV=1)

HSP 1 Score: 634.41 bits (1635), Expect = 0.000e+0
Identity = 344/894 (38.48%), Postives = 513/894 (57.38%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYDSL       NL  AF +AEKHLD+P+ML+ +D+++    DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR+Q      L  +  +F++YR   KP K ++K Q+          + LN + +    +  + S + + W+ +E  E  YEE I  +  R + +++    F     +  +W   K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I   W+ L  L  +R E +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + +I  + G++    NPYT I  Q +   W +    +P+RD  L++ L KQ      +  F+K +  +        EE+  I   +   +   +T      Q +Q  +     ++N+L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD+ +S  L   +F++C++SLGY ++ +++ D +F  IM +VDP NTGF+T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +      LDY +FS  L+
Sbjct:   13 GGPQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYDSLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASDLLEWIRRTIPWLENRTQEKTVKDLQARQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLNNRPAFMPSEGRMVSDINTAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTDGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDAASVNARCQKICEQWDILGSLTHRRKESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLITAHEQFKSTLPEANKEREAIQAIQAEVQKIAQSNGIKLSGANPYTTITPQSIDSKWEKAMAMVPQRDTALQDELNKQNSNDSLRATFAKQANTVGAYIQAKMEEIGRISIEMNGTLEDQLT----NLQEYQKSIMSYMPEINKLEGYHQHIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLYEYRASFNHFDKDHSGALKADEFKACLISLGYDVENDKQGDGEFNRIMGIVDPNNTGFVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNFITADELRRELPPDQAEYCIARMAPYAGPDAVPGA-LDYMSFSTALY 893

[Close]

BLAST of Actinin alpha 4 vs. TrEMBL
Match: A0A3B3XA06 (Actinin alpha 4 OS=Poecilia mexicana OX=48701 GN=ACTN4 PE=4 SV=1)

HSP 1 Score: 629.402 bits (1622), Expect = 0.000e+0
Identity = 342/894 (38.26%), Postives = 513/894 (57.38%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYDSL       NL  AF +AEKHLD+P+ML+ +D+++    DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR+Q      L  K  +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W+ +E  E  YEE I  +  R + +++    F     +  +W   K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I   W+ L  L   R E +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + RI  + G++    NPYT I  Q +   W +    +P+RD  L++ L KQ      +  F+  +  +        EE+  I   +   +   +T      + +Q  +     ++N+L+  +Q++ E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD+ +S  L   +F++C++SLGY ++ +++ D +F  IM +VDP ++GF+T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +G     LDY +FS  L+
Sbjct:   13 GGAQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYDSLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASDLLEWIRRTIPWLENRTQEKTVKDLQAKQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLSNRPAFMPSEGRMVSDINTAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTDGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDAASVNARCQKICEQWDILGSLTHSRKESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLISAHEQFKSTLPEANKEREAIQAIQAEVQRIAQSNGIKLSGANPYTTITPQSIDSKWEKAMTMVPQRDCALQDELNKQNSNDSLRATFAAQANSVGAYIQAKMEEIGRISIEMNGTLEDQLT----NLKDYQKTIMSYMPEINKLEGHHQQIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLFEYRASFNHFDKDHSGGLKAEEFKACLISLGYDVENDKQGDGEFNRIMGIVDPNSSGFVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNFITADELRRELPPDQAEYCIARMAPYAGPDGVPGA-LDYMSFSTALY 893

[Close]

BLAST of Actinin alpha 4 vs. TrEMBL
Match: M3ZLS4 (Actinin alpha 4 OS=Xiphophorus maculatus OX=8083 GN=ACTN4 PE=4 SV=2)

HSP 1 Score: 628.632 bits (1620), Expect = 0.000e+0
Identity = 342/894 (38.26%), Postives = 512/894 (57.27%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYDSL       NL  AF +AEKHLD+P+ML+ +D+++    DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR+Q      L  K  +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W+ +E  E  YEE I  +  R + +++    F     +  +W   K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I   W+ L  L  +R E +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + RI  + G++    NPYT I  Q +   W +    +P+RD  L+  L KQ      +  F+  +  +        EE+  I   +   +   +T      + +Q  +     ++N+L++ +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD+ +S  L   +F++C++SLGY ++ +++ D +F  IM +VDP +TG +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +G     LDY +FS  L+
Sbjct:   13 GGAQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYDSLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASDLLEWIRRTIPWLENRTQEKTVKDLQAKQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLSNRPAFMPSEGRMVSDINTAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTDGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDAASVNTRCQKICEQWDILGSLTHRRKESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLISAHEQFKSTLPEANKEREAIQAIQAEVQRIAQSNGIKLSSANPYTTITPQSIDSKWEKAMAMVPQRDNALQHELNKQNSNDSLRATFAAQANSVGAYIQAKMEEIGRISIEMNGTLEDQLT----NLKEYQKTILSYMPEINKLEAHHQHIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLYEYRASFNHFDKDHSGGLKAEEFKACLISLGYDVENDKQGDGEFNRIMGIVDPNSTGVVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNFITADELRRELPPDQAEYCIARMAPYAGPDGVPGA-LDYMSFSTALY 893

[Close]

BLAST of Actinin alpha 4 vs. TrEMBL
Match: A0A4D9EY28 (Catenin alpha-3-like OS=Platysternon megacephalum OX=55544 GN=DR999_PMT04480 PE=4 SV=1)

HSP 1 Score: 628.246 bits (1619), Expect = 0.000e+0
Identity = 351/894 (39.26%), Postives = 516/894 (57.72%), Query Frame = 1

Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            EY  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR      + +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W   K ++L  +DYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+TL  L  +R + +      L  ID L LEFAKR  P  NW     +DL D F  HST++I+ LI A E FK+T+ EA  E   +  + + I +I    G++   +NPYT++   D+   W  +++ +P RD+TL+E L +Q   +  +  F+  +  L        EE+     DI  SL D M  N  K     Q  Q  +N  A+ +++L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IMMLVDP +TG +T  +F+DF+ ++ +    +EQ V SFKILA+++S I    + +ELP   A+YCI  M  K S        LDY +FS  L+
Sbjct:   88 EYMHQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFISSKGVKLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAFEVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRVAEKSMSAMRRKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLTEIRRLERLEHLAEKFKQKATLHESWTRGKEEMLSQRDYESASLMEVRALMRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNSRCQAICDQWDTLGTLTQKRRDALERVEKLLETIDQLYLEFAKRAAPFNNWMDGATEDLQDMFIVHSTEEIQSLITAHEQFKATLPEADKERMAILGIQNEIQKIAQTYGIKLSGVNPYTNLSHLDIASKWDTVKQLVPHRDQTLQEELARQQANERLRRQFAAQANVLGPWIQTKMEEIGHISVDISGSLEDQM--NHLK-----QQEQNIINYKAN-IDKLEGDHQLIQEALVFDNKHTSYTMEHIRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQMNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMMLVDPNSTGVVTFQAFIDFMTRETAETDTAEQVVASFKILASDKSYITVEELRRELPPEQAEYCISRM-TKYSGADTVSGALDYVSFSSALY 959

[Close]

BLAST of Actinin alpha 4 vs. TrEMBL
Match: A0A4Z2C5U7 (Uncharacterized protein OS=Takifugu bimaculatus OX=433685 GN=fugu_012610 PE=4 SV=1)

HSP 1 Score: 627.861 bits (1618), Expect = 0.000e+0
Identity = 337/884 (38.12%), Postives = 510/884 (57.69%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSK----FSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHE-TLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G  +EY  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL+FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL FCALI  H   LLDY  L+      NL LAF +AEKHLD+P+ML+ +D+I+    DER+IM YVS +YHA    E+ +TA   ICK+L    E  +     + L+  LL W+      L+NR+       +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S + S W  +E+ E  YEE +  +  R + + +    F         W S K   L  KDYETA L+E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D+  + ++   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  H+ ++++ LI A E FK+T+ EA  E   +  + + + +I  + G++   +NPY+ I ++++   W ++++ +P+RD  L+E + +Q   +  +  F+         +   + +I +  F+ +   +  +  + + F+  +      +++L+  +Q + E    DN  T Y+ E +    E  L  +   I++  +  LT +   IS   ++ E+++ F +FDR  +  +D   FR+C++S+GY L E E     F  IMMLVDP  TG ++  SF+DF+ ++ ++   +EQ V SF+ILA ++  I    + +ELP   A+YCI  MP   S  G     LDY  FS  L+
Sbjct:   14 GYEDEYMLQEEEWDRDMLLDPAWEQQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALEFISSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHVSWKDGLAFCALIHRHRPDLLDYSKLNKDDPLGNLNLAFDIAEKHLDIPKMLDAEDIINTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLGVNQENEKMMEEYERLASELLEWIRRTTPWLENRTPEKTMAEMQRKLEDFRDYRRQHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIASAWQGLEQAEKGYEEWLLTEIRRLERLDHLAEKFRQKATNHENWASGKEVFLTQKDYETATLTEIRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDVAAVNQRCQSICDLWDKLGTLTQKRREALERTEKLLETIDQLFLEFAKRSAPFNNWMEGAMEDLQDMFIVHTVEEVQSLIAAHEQFKATLPEADSERQAILGIHNEVLKISQSYGIKAKIVNPYSIITIEELLNKWEKVKKLVPQRDSALQEEMARQHAHERLRRQFAAQANLIGPWIQTRMEEIGRCSFE-IGGTLEDQMTQLKQFEHVIVAYKLNIDKLEGDHQLIQESLVFDNKHTNYTMEHIRVGWELLLTTIARTINEIETQILTRDAKGIS-QQQMNEFRSSFNHFDRKKTGAMDTDDFRACLISMGYDLGEVE-----FARIMMLVDPNATGIVSFQSFIDFMTRETADTDTAEQVVASFRILAADKPYILVEELRRELPPEQAEYCILRMPA-YSGPGTPPGALDYTAFSTALY 889

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Cavefish
Match: ENSAMXT00000048439.1 (pep primary_assembly:Astyanax_mexicanus-2.0:6:17687171:17747843:1 gene:ENSAMXG00000029778.1 transcript:ENSAMXT00000048439.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 608.986 bits (1569), Expect = 0.000e+0
Identity = 339/897 (37.79%), Postives = 513/897 (57.19%), Query Frame = 1

Query:  169 GLGNE-YFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILS-----QEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELS--------DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHE----TLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G G E Y  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +IDN E +FR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL++I  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL FCALI  H   L+DY  L+      NL LA  +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L      +++ E    + S++   N  N        L+NRS     T +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S + S W  +E++E  YEE +  + +R + + +    F        AW + K +LL++KDYETA+L+E++ L R  E+F S++ +H+ R ++I  IA EL  L+Y    TI ++   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  HS ++I++L+ A + FK+T+ EA  E   + S+ + + +I  + G+     N Y  I   ++ + W Q++R +P+RD +L+E L +Q   +  +  F+  +  +   +         D   +L D M+        + + +++ +    + ++ L+  +Q + E    DN  T Y+ E +    E    T+   +NEI       LT +   IS   ++ E+++ F +FDR     ++   FR+C++S+GY L E E     F  IM LVDP   G +T  SF+DF+ ++ +    +EQ   SF+ILA ++  I    + +ELP   A+YCI  MP+    +G     LDY  FS  L+
Sbjct:    7 GYGQEEYMLQEDEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIDNIEEEFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALEYITSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHCSWKDGLAFCALIHRHRPDLIDYSKLNKDDPLGNLNLALEIAEKHLDIPKMLDPEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLGVNQENEKLMEDYEKLASEVRPINSWNGSGAPPPWLENRSSETTMTAMRKKLEDFRDYRRLHKPPKVQEKCQLEISFNTLQTKLRISNRPAFMPSEGKMVSDIASAWQGLEQVEKGYEEWLLTEIHRLERLNHLAEKFNQKASTHEAWANGKDELLMAKDYETASLTEVRALLRRHESFESDLAAHQDRVEQIAAIAQELNELDYHASATINERCQRICDQWDQLGTLTQKRREALERTEKLLETIDQLFLEFAKRSAPFNNWMEGAMEDLQDMFIVHSVEEIENLMGAHDQFKATLPEADTERQAIMSIYNEVQKIAQSYGIAPNLTNMYCSITPAEISQKWEQVKRLVPQRDSSLREELSRQQVNERMRRQFAAQANSIGPWIQARMEVNSVDAGGTLEDQMN--------QLKQYESMIINYKTNIDRLEGDHQVIQESLIFDNKHTNYTMEHIRVGWELLLTTIARTINEIETQI---LTRDAKGIS-QQQLNEFRSSFSHFDRKKKGGMETDDFRACLISMGYDLGEAE-----FARIMSLVDPNGKGLVTFQSFVDFMTRETTEMDTAEQVAASFRILAADKPYILIEELRRELPPEQAEYCISRMPLYAGPDGVPGA-LDYSAFSTALY 885

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Cavefish
Match: actn4 (actinin alpha 4 [Source:NCBI gene;Acc:103022122])

HSP 1 Score: 604.749 bits (1558), Expect = 0.000e+0
Identity = 327/886 (36.91%), Postives = 506/886 (57.11%), Query Frame = 1

Query:  184 YFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIH-NKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDM---MSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            Y + +SD + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYD L       NL  AF +AEK+LD+P+ML+ +D  +  K+  E++IM YVS +YHA    +K +TA   ICK+L+   E      + + L+ +LL W+   I  L+NR+       +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S +   W+++E  E  YEE +  +  R + + +    F     +  +W   K  +L  KDYETA+LSE+K L +  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I   W+ L  L   R E +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FK+T+ EA  E   ++++   + +I    G++    NPYT I    +   W ++++ +P+RD+ L+E L +Q      +  F+  +  +   + +  + +  +   M+  +  +    + ++  +      +++L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+T F +FD+ +   L   +F++C++SLGY ++ N++ D +F  IM +VDP N+G +T  +F+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +      LDY +FS  L+
Sbjct:   18 YMEPESDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIDYDKLRKDDPVTNLNNAFEVAEKYLDIPKMLDAEDTWYAAKERYEKAIMTYVSCFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLENRAPEKTMAEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGRMVSDINGAWHKLEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKATIHESWTDGKEAMLTQKDYETASLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICEQWDVLGSLTQSRRESLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLITAHEQFKATLPEANKEREAIQAIQAEVQKIAQYNGIKLAGTNPYTTITPSSIDSKWDKVQKLVPQRDQALQEELARQQSNDHLRRQFANQANIVGPWIQNKMEEIGRISIEMNGTLEDQLTHLRQYEQSIIDYKPNIDQLEGNHQLIQEALIFDNKYTAYTMEHLRVGWEQLLTTIARTINEIENQI-------LTRDAKGIS-QEQLHEYRTSFNHFDKDHGGALQAEEFKACLISLGYDVENNKQGDAEFARIMGIVDPNNSGAVTFQAFIDFMSRETTDTDTADQVIASFKILAGDKNYITAEELRRELPPDQAEYCIGRMAPYAGPDAVPGA-LDYMSFSTALY 894

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Cavefish
Match: actn2b (alpha-actinin-2 [Source:NCBI gene;Acc:103024106])

HSP 1 Score: 604.364 bits (1557), Expect = 0.000e+0
Identity = 324/880 (36.82%), Postives = 504/880 (57.27%), Query Frame = 1

Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSK----FSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHE-TLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            +Y  ++ + + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PD+GKMRFHKIANVNKAL+FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL FCALI  H   L+DY  L+      NL LAF +AEKHLD+P+ML+ +D+++    DER+IM YVS +YHA    E+ +TA   ICK+L    E  +     + L+  LL W+      L+NR      T +  K+ +F++YR   KP K ++K Q+          + ++ + +    +  + S + S W  +E+ E  YEE +  +  R   + +    F         W + K ++L  KDYE+A+L E++ + R  E F S++ +H+ R ++I  IA EL  L+Y D+ ++ ++   I + W+ L  L  +R E +      L  ++ L LE+AKR  P  +W    ++DL D F  H+ ++++ L+ A E FK+T+ EA  E   +  +   + +I  + G++    NPY+ I  + +   W ++++ +P+RD  L+E L +Q G +  +  F+         +   + +I +   + +   +  +  + + ++  +      +++L+  +Q + E    DN  T Y+ E +    E  L  +   I+   +  LT +   IS   +++E+++ F +FDR  +  ++   FR+C++S+GY L E E     F  IMMLVDP   G +T  SF+DF+ ++ ++   +EQ V SF+ILA ++  I    + +ELP   A+YCI  MP   +  G     LDY  FS  L+
Sbjct:   20 DYMMQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALEFITSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHVSWKDGLAFCALIHRHRPDLIDYAKLNKDDALGNLNLAFEIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANRICKVLGVNQENEKLMEEYERLASELLEWIRRTTPWLENRMSEKTMTQMQQKLEDFRDYRRLHKPPKVQEKCQLEINFNTLQTKLRISNRPAFMPSEGKMVSDIASAWQGLEQAEKGYEEWLLTEIRRLQRLDHLAEKFRQKATSHETWATGKEEILTQKDYESASLMEVRAMLRKHEAFESDLSAHQDRVEQIAAIAQELNELDYHDVASVNQRCQSICDVWDHLGTLTQKRREALERTEKLLETVEQLFLEYAKRSAPFNSWLDGAMEDLQDMFIVHTIEEVQSLMAAHEQFKATLPEADAERQAILGIQQEVQKIFHSYGIRGDLTNPYSTISPETILSKWDKVKKLVPQRDGALQEELAQQHGNERLRRQFAAQANLIGPWIQTRMEEIGRCSLE-IGGTLEDQMTQLKQYEHVIVSYKPNIDKLEGDHQLIQESLIFDNKHTNYTMEHIRVGWELLLTTIARTINDIETQILTRDAKGIS-PEQMKEFRSSFNHFDRKKNGAMETDDFRACLISMGYDLGEVE-----FARIMMLVDPNACGVVTFQSFIDFMTRETADTDTAEQVVASFRILAADKPYILIDELRRELPRDQAEYCISRMP-PYAGPGAMPGALDYTAFSTALY 891

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Cavefish
Match: actn3a (actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-9])

HSP 1 Score: 601.668 bits (1550), Expect = 0.000e+0
Identity = 344/894 (38.48%), Postives = 506/894 (56.60%), Query Frame = 1

Query:  181 EYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            EY  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK LD+P+ML+ DD+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR        +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + +++    F+    +  +W + K  LL  KDYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  TI  +   I + W+ L  L  +R + +         ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A + FK+T+ EA  E      + + I +I    G++    NPYT I  QD+   W  +++ +P RD+ L+E + +Q   +  +  F+  +  +        EE+S    DI  SL + M +         + ++  +    S +++L+  +Q   E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVD  NTG +T  +F+DF+ ++ +    +EQ + SFKILA++++ I    + +ELP   A+YCI  M   +  N   +  LDY +FS  L+
Sbjct:   21 EYMIQEDDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFICSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFEVAEKFLDIPKMLDADDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRVAEQTMPAMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLTEIRRLERLEHLAEKFKQKCTLHESWTAGKEQLLSLKDYESASLMEIRALMRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAATINARCQGICDEWDNLGTLTQKRRDSLERVEKLWETIDQLFLEFAKRAAPFNNWMDGAMEDLQDMFIVHSIEEIQSLITAHDQFKATLPEADKERMATMGIQNEILKIAQTYGIKLTGENPYTVISPQDISNKWEAVKQLVPMRDQMLQEEVARQQSNERLRRQFAAQANIIGPWIQTKMEEISHVSIDIAGSLEEQMGN--------LKQYEQNIINYKSNIDKLEGDHQLSQEGLIFDNKHTNYTMEHVRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDANNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKTYITVEELRRELPPEQAEYCISRMTRFVGVNAPADA-LDYISFSSALY 892

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Cavefish
Match: actn1 (actinin alpha 1 [Source:NCBI gene;Acc:103031817])

HSP 1 Score: 599.742 bits (1545), Expect = 0.000e+0
Identity = 327/896 (36.50%), Postives = 500/896 (55.80%), Query Frame = 1

Query:  163 FEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            ++G  N+Y  ++ D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + L  P++GKMR HKI+NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ ++NF  S++DGL FCALI  H   L+DY  L       NL  AF +AEK+LD+P+ML+ +D++     DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ +LL W+   I  L+NR        +  K+ +F++YR   KP K ++K Q+          + L+ + +    +  + S + + W  +E  E  YEE +  +  R + + +    F     +  AW   K  +L  KDYET  LSE+K L +  E F S++ +H+ R ++I  IA EL  L Y D  ++  +   I + W+ L  L  +R E +      L  ID L LEFAKR  P  NW +  ++DL D F  H+ ++I+ L  A E FK+T+ EA  E   +  + + I +IV    +     NPYT I   ++   W ++ + +P+RD+ L E   +Q   +  +  F+  +  +        EE+  I   L   +   +T      + ++  +     ++++L+  +Q++ E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR +S  L   +F++C++SLG+ +  + + + +F  IM +VDP   G +T  +F+DF+ ++ ++   ++Q + SFK+LA +++ I    + +ELP   A YCI  M      +      LDY +FS  L+
Sbjct:   14 YDGDENDYMQQEDDWDRDMLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALNFITSKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYAKLRKDDPMTNLNTAFDVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPESTMQAMQQKLEDFRDYRRQHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDISNAWGALEGAEKGYEEWLLNEIRRLERLDHLAEKFRQKAAIHEAWTEGKEAMLTQKDYETVTLSEIKALLKKHEAFESDLAAHQDRVEQIAAIAQELNELEYYDSPSVNARCQKICDQWDALGALTQKRSEALQRTEKLLETIDQLYLEFAKRAAPFNNWMEGAMEDLQDTFIVHTIEEIQGLSTAHEQFKATLPEADKERQAILGIHNEIAKIVQTYHVNMAGTNPYTTINPTEINAKWDKVRQLVPQRDQALIEEHARQQNNERLRRQFANQANVIGPWIQTKMEEIGRISIELHGTLEDQLT----NLRQYEKSIVNYKPKIDQLEGDHQQIQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEIENQI-------LTRDAKGIS-QEQLSEFRASFNHFDRDHSGTLGAEEFKACLISLGFDIGNDAQGEAEFARIMSIVDPNRLGVVTFQAFIDFMSRETADTDTADQVMASFKVLAGDKNYILADELRRELPPDQADYCISRMAPYTGPDAVPGA-LDYMSFSTALY 896

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009295.1 (pep scaffold:Pmarinus_7.0:GL479988:2885:20778:1 gene:ENSPMAG00000008383.1 transcript:ENSPMAT00000009295.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 567.77 bits (1462), Expect = 0.000e+0
Identity = 310/860 (36.05%), Postives = 487/860 (56.63%), Query Frame = 1

Query:  256 TFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEH--WIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHET-LNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            TFTAWCN+HLRKA   I+N + DFR+GLKLM LLE+IS + L  P++GKMR HKI+NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DY+ L       NL  AF +AEK+LD+P+ML+ +D++     DE++IM YVS YYHA    +K +TA   ICK+L+   E  +   + + ++ +LL+W+    W   L+NR   +    +  K+  F++YR   KP K ++K Q+          + L  + +    +  + S + + W+ +E+ E  YEE +  +  R + + +    F    ++  AW + K  +L  +DY++ +L+ELK L R  E F S++ +H+ R ++I  IA EL  L+Y D+ ++  +   I   W+ L  L  +R + +      L  ID L LEFAKR  P   W    ++DL D F  H+ D+I+ LI A E FK T+ EA  E + +  + + I ++     ++    NPY+ I   D+   W ++ + +P RD +L++ L +Q   +  +  F+  +  +        EE+  I   +   +   +     + + ++  +      +++L+S  Q + E    DN  T Y+ E +    E  L  +   I++  +  LT +   IS   ++ E++  F +FD+ +S KL   +F++C++SLGY +  +++ + +F  IM +VDP NTG +T  SF+DF+ ++ ++   ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +      LDY +FS  L+
Sbjct:    1 TFTAWCNSHLRKAGTGIENIDEDFRNGLKLMLLLEVISGERLAKPERGKMRVHKISNVNKALDFIASKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYEKLRKDDPITNLNNAFEVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSCYYHAFSGAQKAETAANRICKVLAVNQENEKLMEDYEHMASDLLDWIRRTPW---LENRVPENTMQAMQGKLEGFRDYRRVHKPPKAQEKCQLEISFNTLQTKLRLMNRPAFMPSEGKMVSDIANGWSMLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKAKIHEAWTAGKEAMLEKRDYDSVSLTELKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDVASVNARCQDICAEWDKLGDLTQRRKDTLERTEKVLETIDQLYLEFAKRAAPFNTWMDGAVEDLQDMFIVHTIDEIQGLISAHEQFKDTLPEAEKEKSAILGVHNEIQKVAQTYNVKLAGPNPYSAITPHDISSKWERMTQQVPLRDDSLRDLLARQQANETLRRQFAASANIVGPWIQTKMEEIGHISIEMHGTLEDQLN----QLRRYEQNIINYKPNIDKLESEYQLVQEALIFDNKHTNYTMEHIRVGWEQLLTTIARTINEVETQILTRDAKGIS-QEQMHEFRASFNHFDKDHSGKLGAEEFKACLISLGYDVGNDQQGEAEFARIMTVVDPNNTGLVTFQSFIDFMTRETTDTDTADQVIASFKILAGDKNFITADELRRELPPDQAEYCIARMAPYRGPDAVPGA-LDYMSFSTALY 851

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000684.1 (pep scaffold:Pmarinus_7.0:GL483163:49540:93186:-1 gene:ENSPMAG00000000623.1 transcript:ENSPMAT00000000684.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 426.017 bits (1094), Expect = 5.353e-139
Identity = 221/507 (43.59%), Postives = 306/507 (60.36%), Query Frame = 1

Query:  256 TFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTD 1746
            TFTAWCN+HLRKA  +ID+ + DFR GLKLM LLE+IS++ LP P+KGKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN KMTLGMIWTIILRF IQ+I +E++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DYD L       NL  AF +AEK+LD+P+ML+ +D+++    DE++IM YVS YYHA    +K +TA   ICK+L+   E    S         LL W+   I  L++R+  ++   +  K+ +F++YR   KP K  DK Q+          + L  + +    +  + S + + W+ +E+ E  YEE +  +  R + + +    F    ++ ++W   K  +L  KDYE+ +L+ELK L +  E F S++ +H+ R ++I  IA EL  LNY D+ ++  K   I + W+ L      R + ++     L  ID L LEFAKR  P   W     +DL D F  H+ D
Sbjct:    5 TFTAWCNSHLRKAGTQIDSIDEDFRDGLKLMLLLEVISSERLPKPEKGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNTKMTLGMIWTIILRFAIQDISIENTSAKEGLLLWCQRKTAPYKNVNVQNFHTSWKDGLAFNALIHRHRPDLIDYDKLRKDDPIGNLNNAFEVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSCYYHAFSGAQKAETAANRICKVLAVNHERVDLSCACVRARLQLLEWINRTIPVLEDRNTQNNMPAMQGKLEDFRDYRRVHKPPKAGDKCQLEINFNTLQTKLRLMNRPAFMPSEGKLVSDIGNAWSHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQKAKIHKSWTEGKQQMLQQKDYESVSLAELKALLKKHEAFESDLAAHQDRVEQIAAIAQELNDLNYHDVASVNTKCKEICDEWDDLGEWTQTRKDSLSRTEKVLETIDHLYLEFAKRAAPFNTWMDGAAEDLQDMFIVHTID 511

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BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004049.1 (pep scaffold:Pmarinus_7.0:GL476488:489896:554954:1 gene:ENSPMAG00000003699.1 transcript:ENSPMAT00000004049.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 299.671 bits (766), Expect = 4.370e-87
Identity = 166/476 (34.87%), Postives = 273/476 (57.35%), Query Frame = 1

Query:  238 EAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILV--EDS----SAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEK--NKDKIQIMYLNLK---KSTEKKKF-----NICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINS 1617
            E  Q  TFT W N+HL + S +I +   D R G  L+KLLE++S + LP P KGKMR H + NV KAL+F++E+ V L ++G+ +IVDGN ++TLG+IWTIILRF IQ+I V  EDS    SAK+ LLLWC+ KT GY N++V NF  S++DGL F ALI  H   L+D+D+L P+    N++ AF +AE+ L + Q+L+ +D I  +  DE+S++ YV +YYH   + + +    K I K+L   ME  Q     D L+ +LL+W+E  I  L NR+  +  T +  ++  F +YR  +KP K   K  ++++   ++   ++  +K F      + S +   W  +EK E+  E  + E+  R + ++     F+    ++ +W++     LV +D   ++L+ ++   +  E   +++ +++ R   ++++A EL+  NY D+  +  +   +L  W  L  L C R  R+ +
Sbjct:    5 EEVQKKTFTKWVNSHLSRVSCRIGDLYADLRDGRMLIKLLEVLSGERLPKPTKGKMRIHCLENVEKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDSREVKSAKDALLLWCQMKTAGYPNVRVHNFTTSWRDGLAFNALIHKHRPDLIDFDALDPADPYGNMQTAFNVAEQKLGLTQLLDAED-IAVEHPDEKSVITYVVTYYHYFSKMKALAVEGKRIGKVLESAMETDQMIEKYDSLASDLLDWIEQTIAILNNRTFANSLTGVQQQLQAFSSYRTVEKPAKFTEKGNLEVLLFTIQSRMRANNQKVFLPGEGKLISEINKAWERLEKAEHERELALREELIRQEKLEQLARRFDRKAAMRESWLTEN-QCLVLQDNFGSDLAAVEAATKKHEAIETDMAAYEERVHAVLHVAQELQAENYHDVARVAARRDNVLRLWRYLQELLCGRRARLEA 478

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BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008111.1 (pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 gene:ENSPMAG00000007298.1 transcript:ENSPMAT00000008111.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 278.485 bits (711), Expect = 1.023e-77
Identity = 159/478 (33.26%), Postives = 261/478 (54.60%), Query Frame = 1

Query:  238 EAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDS------SAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFL 1623
            EA Q  TFT W N+HL + S +I +   D R G  L+KLLE++S + LP P +GKMR H + NV+KAL+F++E+ V L ++G+ +IVDGN ++ LG+IWTIILRF IQ+I VE        SAK+ LLLWC+ KT GY+N+ + NF  S++DGL F A++  H   L+++D L  S   HNL+ AF +AE+ L + ++L+ +D I     DE+SI+ YV +YYH   + + +    K I K+L   +E  Q     + L+  LL W+E  I  L NR   +  T +  ++  F  YR  +KP K  +K  +          M  N +K    ++  + + +   W  +EK E+  E  +  +  R + ++     F+    ++  W+S     LV++D    +L  ++   +  E   +++ +++ R   +V++A EL+  +Y ++  +  +   +L  WE L  L   R  R+ + L
Sbjct:   56 EAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGEKLPKPTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDISVETEDNKERRSAKDALLLWCQMKTAGYQNVNIHNFTTSWRDGLAFNAIVHKHRPDLIEFDKLKKSNAHHNLQNAFNIAEQKLGLTKLLDPED-ISVDQPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLESAIETDQMIDKYETLASELLEWIEQTIIILNNRKFANSLTGVQQQLQAFSTYRTVEKPNKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLVNEINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAALRETWLSEN-QRLVTQDNFGVDLPAVEAATKKHEAIEADIAAYEERVQAVVDVARELEAEDYHEVRRVCSRRDNVLRLWEYLQELLAARRHRLEANL 531

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BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001834.1 (pep scaffold:Pmarinus_7.0:GL482425:158920:175005:1 gene:ENSPMAG00000001663.1 transcript:ENSPMAT00000001834.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 232.261 bits (591), Expect = 4.663e-63
Identity = 133/430 (30.93%), Postives = 229/430 (53.26%), Query Frame = 1

Query:  382 PAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILV--EDS----SAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFL 1623
            P P +GKMR H + NV+KAL+F++E+ V L ++G+ +IVDGN ++ LG+IWTIILRF IQ+I V  EDS    SAK+ LLLWC+ KT GY N+ V NF  S++DGL F A+I  H   L+D++ L  S   HNL+ AF  AE+HL V ++L+ +  +     DE+SI+ YV S+YH   + + +    K I K+L   +E  +     + L+  LL W+   I  L +R   +    +  ++  F +YR  +KP K  +K  +          M  N +K    ++  + + +   W  +EK E+  E  + ++  R + ++     F+    ++  W++    L++  ++  A+L+ ++   +  E   +++ +++ R   +  +A EL+   Y ++  + ++   +L  W  L  L   R  R+   L
Sbjct:    1 PKPTRGKMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLILGLIWTIILRFQIQDISVQTEDSKETRSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAVIHKHRPDLVDFEKLKKSNAQHNLQHAFNAAEQHLGVTKLLDPEADVSVDQPDEKSIITYVVSFYHYFSKMKALAVEGKRIGKVLDSAIEADRMVERYESLASELLEWIGRTITALNSRDFPNSLVGVQQQLHAFSSYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYTPREGKLVAEINRAWERLEKAEHGRELALRDELIRQEKLEQLARRFDRKAAMRETWLAENQRLVMQDNF-GADLAAVEAATKKHEAIETDMAAYEGRVRAVEGVARELEAERYHEVARVVRRRDGVLQLWRRLQELLAARRTRLEMTL 429

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BLAST of Actinin alpha 4 vs. Ensembl Yeast
Match: SAC6 (Fimbrin, actin-bundling protein; cooperates with Scp1p in organization and maintenance of the actin cytoskeleton; phosphorylated by Cdc28p/Clb2p in metaphase on T103, to regulate conformation, and modulate actin filament binding affinity and actin cable dynamics; relocalizes from the plasma membrane to the cytoplasm upon DNA replication stress; human homologs PLS3 and LCP1 implicated in spinocerebellar ataxia type 2 (SCA2) can each complement yeast null mutant [Source:SGD;Acc:S000002536])

HSP 1 Score: 60.077 bits (144), Expect = 1.368e-9
Identity = 52/201 (25.87%), Postives = 89/201 (44.28%), Query Frame = 1

Query:  244 QQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNL--------PAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKE----GLLLWCKRK-TNGYKNIKVENFKN-SFQDGLVFCALIDSHDKSLLDYDSLSPSQISH----NLKLAFTLAEK 792
            ++   FT W N+ L      I  F+ D + GL L++  E +    +        PA      RF  + N N A+     KG  L  I   +IVDGN  +TLG++W ++ R     +    SS ++     +L W + + T G KN  + +FK+ +  +      +++      +DYD ++P         N +LA ++A K
Sbjct:  412 REARVFTLWLNS-LDVDPPVISLFD-DLKDGLILLQAYEKVMPGAVDFKHVNKRPASGAEISRFKALENTNYAVDLGRAKGFSLVGIEGSDIVDGNKLLTLGLVWQLMRRNISITMKTLSSSGRDMSDSQILKWAQDQVTKGGKNSTIRSFKDQALSNAHFLLDVLNGIAPGYVDYDLVTPGNTEEERYANARLAISIARK 610

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BLAST of Actinin alpha 4 vs. Ensembl Yeast
Match: CMD1 (Calmodulin; Ca2+ binding protein that regulates Ca2+ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca2+ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin; binds to the Hog1p MAPK in response to hyperosmotic stress; potentiates membrane tubulation and constriction mediated by the Rvs161p-Rvs167p complex; human CALM1 or CALM2 functionally complement repression induced inviability [Source:SGD;Acc:S000000313])

HSP 1 Score: 45.0542 bits (105), Expect = 7.506e-6
Identity = 33/127 (25.98%), Postives = 58/127 (45.67%), Query Frame = 1

Query: 2305 SPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAK 2685
            S NLT  Q        + E+K  F  FD+ N+  +  S+  + M SLG S  E E ND     +M  +D +    I  + FL  + ++  +    ++ +E+FK+   N   +  A  L+ +  +I +
Sbjct:    2 SSNLTEEQ--------IAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVND-----LMNEIDVDGNHQIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGE 115

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BLAST of Actinin alpha 4 vs. Ensembl Nematostella
Match: ALPHA-ACTININ (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4X0])

HSP 1 Score: 564.688 bits (1454), Expect = 0.000e+0
Identity = 313/900 (34.78%), Postives = 504/900 (56.00%), Query Frame = 1

Query:  184 YFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPL-------NPYTDIMLQ-----DVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA---EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHST 2784
            YF  + DK     +DP WE QQ  TFTAWCN+HLRK   +I   E D R G+ L++LLEIIS + LP P++GK+RFH+IANVNKAL F+  KGVKL S+GAEEIVDGN+KMTLGMIWTIILRF IQ+I +EDS AK+GLLLWC+RKT  YKN+ V+NF  SF+DGL FCALI  H   L+DYDSL      +NL  AF +AE++LD+P+ML+ +DM+  +  DER++M YVSSYYHA    ++ DTA K I K+L+   +  +   + + L+ +LL+W+   +  L +R        +  K+   +NYR  +KP K ++K Q+          + L+ + +    +  + + +   W  +E  E  +E+ +  +  R + + +    F     +  +W + K  +L   DY  A L+++  L +  E F S++ +H+ R D+IV IA EL  L Y  ++ +  +   I + W+ L  L   R++++      L  +D L+LEFAK+  P  NW +   +DL D F+ H+ ++I++L+ A E FK  +  A  E     S+ D   +I + +G Q+ P        +P TD++       D+ + W Q+   +P+RD  L++   KQ   +  +  F+  +  +    ++  +  +++   M  ++ K     Q  +T +      + EL+ INQ++ +    +N  T Y+ E         L+AI   +N + N+I    S  +T  Q        ++E++  F +FD+  + KL+ ++F+ C++SLGY++ E ++ DR+F+ ++ +VDP  TG +T  +F+DF+ ++ ++   +EQ +ESF+ILA ++  I    + +ELP   A+YCI  M             LDY +FS  L+  +
Sbjct:   11 YFYGEEDKGL---LDPAWERQQKKTFTAWCNSHLRKTGKQIGEIEEDLRDGVLLLQLLEIISGERLPHPERGKLRFHRIANVNKALDFVAGKGVKLVSVGAEEIVDGNLKMTLGMIWTIILRFAIQDIAIEDSFAKDGLLLWCQRKTAPYKNVSVKNFTTSFKDGLAFCALIHRHRPDLIDYDSLRKEDPLYNLNKAFDVAEQYLDIPRMLDPEDMVETERPDERAVMTYVSSYYHAFTSSQQADTAAKRIGKVLNINRDNERMMEDYERLASDLLDWINKTMPWLTSRDTDGTLKDMQRKLDELRNYRKGEKPPKVEEKGQLETNFNTLQTKLRLSNRPAYLPSEGKMINDINDAWGGLEMAEKDFEDWLLMEMRRMERLDHLAEKFRHKCNIHESWTNGKDAVLSKDDYSDATLADINALMKKHEAFESDLAAHQDRVDQIVAIAQELNALEYSKIDEVNARCQNICDDWKDLGELTMHRLQKLEDAQQRLQSLDQLRLEFAKKAAPFNNWLESAREDLMDMFSVHTVEEIQELLDAHEAFKENMPAAQAEYN---SIMDIAVQIESLSG-QENPYTSLSKEASPITDMLFTFVFVCDINEGWNQVVDLVPKRDILLRDERSKQDRNERLRVEFANKANVVGPWIQQQGEKLRTIGFHMEGSLEKNLQVLQDLETFITSYKPNIEELEVINQEVQQALIFENPHTKYTMEAMRVGWEQLLTAIARNINEVENQILTRDSKGITEEQ--------MKEFRASFNFFDKDQTGKLEPNEFKQCLVSLGYNIKEGDKGDREFERLLGIVDPNGTGKVTFQAFVDFMTRETADSDTAEQVMESFRILAGDKPFITAEELRRELPPDQAEYCIARM-APYEGKDAVPGALDYMSFSTALYGES 894

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BLAST of Actinin alpha 4 vs. Ensembl Nematostella
Match: EDO42431 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1C0])

HSP 1 Score: 265.388 bits (677), Expect = 3.512e-73
Identity = 157/471 (33.33%), Postives = 262/471 (55.63%), Query Frame = 1

Query:  247 QISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDS-----SAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKD-SDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKP----EKNKDKIQIMYLNLKKSTEKKKFNICST------VQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERI 1611
            Q  TFT W N+HL++   +++    D + G KL+ LLE++S + LP P KG+MR H + NV K+L F++++ V L ++GA +IVDGN K+TLG+IWTIILRF IQ+I +E       SAK+ LLLWC+ KT GY ++ + NF  S++DGL F A+I  H   L++++ L+ +    NL+ AF +AE  L +  +L+ +D+  N D  DE+SI+ YV++YYH   + + ++ +   I K++ +  E  +  I+ + L+ +LL W+E  I +L  R   +    +  ++  F  YR  +KP    EK   ++Q+  L  K     +K  I         +   W  +EK E+  E  + E+  R + ++     F+  + ++  W+ N+   LV+ D    +L+ ++   +  E   +++ +++ R + IV +A EL R NY D E I+     I+  WE L  L  QR  R+
Sbjct:   26 QKKTFTKWINSHLQRVGARVNELYHDLQDGRKLILLLEVLSGEKLPKPSKGRMRIHNLENVEKSLVFLKKQRVHLENVGAHDIVDGNQKITLGLIWTIILRFQIQDITIEGETTEKRSAKDALLLWCQSKTVGYVHVTITNFTTSWRDGLAFNAIIHRHRPDLIEFEKLTKADAEQNLEQAFEVAETQLGITPLLDAEDV--NVDFPDEKSILTYVAAYYHYFAKMKTVEVSGSRIGKVIERIKENEELIIDYEKLASDLLEWIEIKIIQLGEREFANTLLGVQQQMLEFNQYRTQEKPPRFVEKGNLEVQLFILTSKIRANHQKPYIPPEGRGMIDINRAWERLEKSEHERELALREELMRQERLEMLAAKFDRKYAMRETWL-NENQRLVAVDNFGNDLAAVEAATKKHEAIETDIMAYEERVNAIVAVAEELHRENYHDSERIQVCKGRIIQLWELLLVLIKQRRVRL 493

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BLAST of Actinin alpha 4 vs. Ensembl Nematostella
Match: EDO49576 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RGP7])

HSP 1 Score: 245.743 bits (626), Expect = 8.067e-69
Identity = 154/469 (32.84%), Postives = 254/469 (54.16%), Query Frame = 1

Query:  247 QISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVED------SSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILS-----QEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI--MYLNL---KKSTEKKKF-----NICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKI----DLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETL 1578
            Q  TFT W N+ L K+ + +++   D   G  L+ LLEIIS + +    +GK R H I NVNKAL+F++ K VKL SIGAE++VDGN ++ LG+IW IILRF I +I  +D       SAKE LLLWC+R T GY  + ++NF  S+++GL F AL+  H   L+DY +L PSQ   NL  AFT+A + L + ++L+ +D +     D+RS+M YV++YY    + +  +T  + I KI+      ++ME+S  S+ SD     LL+W+   I EL  R    +   +  ++  FK++R  +KP K  +++ I     NL   +K+  ++ F      +   +   W  ME  E+   + +  +  R  +++     F+    ++ +W+ + +    D L+ +D  T   + LK+     E  +++V + + R   + N+A EL   +Y   + I K+  +I+  W+ L
Sbjct:   25 QKKTFTKWVNSFLDKSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFLQ-KSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADISYQDDMSKERKSAKEALLLWCQRMTRGYPGVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAAEKLGITRLLDAED-VDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIAKIIGVIMEIEKMEKSYESMVSD-----LLHWISSKITELA-RPFEKNIFAVQRELGAFKHFRTVEKPPKYTERVNIEAHLFNLQTKRKANNQRPFAPPEGKLVKDINRAWQVMESAEHERAQALRNELIRQQMLEKMAEKFQRKADLRESWLDDMVQVIDDELLGQDAATVEAA-LKR----HEAISTDVKAREERFQMVFNLAQELIDEDYYKADVIRKREDVIMVKWDKL 480

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BLAST of Actinin alpha 4 vs. Ensembl Nematostella
Match: EDO29101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T4L2])

HSP 1 Score: 218.394 bits (555), Expect = 3.304e-63
Identity = 125/315 (39.68%), Postives = 189/315 (60.00%), Query Frame = 1

Query:  247 QISTFTAWCNAHLRK--ASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVED------SSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILS-----QEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI 1152
            Q  TFT W N+ L K  + + +++   D   G  L+ LLEIIS + +    +GK R H I NVNKAL+F++ K VKL SIGAE++VDGN ++ LG+IW IILRF I +I  +D       SAKE LLLWC+R T GY ++ ++NF  S+++GL F AL+  H   L+DY +L PSQ   NL  AFT+AE+ L + ++L+ +D +     D+RS+M YV++YY    + +  +T  + I KI+      ++ME+S  S+ SD     LL+W+   I EL  R    +   +  ++  FK++R  +KP K  +++ I
Sbjct:   25 QKKTFTKWVNSFLDKVRSGLHVNDLFEDLADGKILISLLEIISGEKIGFAARGKFRVHNIQNVNKALEFLQ-KSVKLESIGAEDVVDGNERLILGLIWMIILRFQIADISYQDDMSKERKSAKEALLLWCQRMTRGYPDVDIQNFSTSWRNGLAFNALLHKHRPDLIDYATLRPSQHEANLNNAFTVAEEKLGITRLLDAED-VDCPRPDDRSVMTYVAAYYQYFAKLKSEETGGRRIAKIIGVIMEIEKMEKSYESMVSD-----LLHWISSKITELA-RPFEKNIFAVQRELGAFKHFRTVEKPPKYTERVNI 331

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Nematostella
Match: EDO37708 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SF38])

HSP 1 Score: 179.104 bits (453), Expect = 1.604e-45
Identity = 120/322 (37.27%), Postives = 187/322 (58.07%), Query Frame = 1

Query:  238 EAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVE-------DSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVK--ISNFKNYRFYDKPE--KNKDKIQIMYLNLK 1170
            +A Q  TFT W N  L K  ++I +   + R G  L+ LLE++ N  LP  ++G +RFH + NV  AL+F+E K +KL +I +++IVDGN K+TLG+IWTIIL F I ++ VE       D SAK+ LL W K+ T GY  + V+NF +S++DG  F A+I  +   L+D+  LS +    N++ AF +AEK L+VP++L+++D++ +++ DE+SIM YV+S Y    R   +  +L +  K L  E        N    +KNL++ V   I  L+   Q   +T   +K  I  F  YR  + P+    +  I+++Y NL+
Sbjct:   36 DAVQKKTFTKWVNNRLLKVGVRILDLYEELRDGEDLLLLLEVLCNVKLPR-ERGLLRFHMLQNVQTALEFLESKKIKLVNIRSDDIVDGNPKLTLGLIWTIILYFQINDLDVEIAGEKVQDLSAKDALLHWSKKVTQGYPKVDVKNFSSSWRDGFAFNAIIHRYRPDLVDFSKLSKTSPEANIEYAFHVAEKELNVPRLLDVEDVVVSENPDEKSIMTYVASLYEVFPRTPTVQESLHDNEKQLKYE-----EYCN---YAKNLVDLVNDVISNLEK--QKIPRTIQGIKELILAFNRYRITEYPDMVATRHSIKMLYKNLQ 346

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Medaka
Match: ENSORLT00000001151.2 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 618.231 bits (1593), Expect = 0.000e+0
Identity = 342/905 (37.79%), Postives = 514/905 (56.80%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNS-----------NKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DY+SL       NL  AF +AEKHLD+P+ML+ +D+++    DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ NLL W+   I  L++R+Q      +  K  +F++YR   KP K ++K Q+          + L+ + +    +  + S + S W+ +E  E  YEE I  +  R + +++    F     +  +W + K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+TL  L   R + +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + +I  + G++    NPYT I  + +   W Q    +P+RDK L+  L KQ      +  F+K +  +        EE+  I   +   +   +T      + +Q  +     ++N L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD++ S             L   +F++C++SLGY ++  ++ D +F  IM +VDP N+G +T  +F+DF+  + +++  ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +G     LDY +FS  L+
Sbjct:   13 GGPQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYESLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASNLLEWIRRTIPWLEDRTQQKTVNDMQAKQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLSNRPAFMPSEGRMVSDINSAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTNGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSASVNNRCQKICDQWDTLGTLTHSRKDSLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLIAAHEQFKSTLPEANKEREAIQAIQAEVQKIAQSNGIKLSGANPYTTITPRSIDDKWEQAMAMVPQRDKALQGELNKQNSNDTLRATFAKQANVVGGYIQAKMEEIGRISIEMNGTLEDQLT----HLREYQQTILFFMPEINTLEGYHQHIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLYEYRASFNHFDKSTSGAEKGGRCDHTGSLIAEEFKACLISLGYDVENEKQGDAEFTRIMSIVDPNNSGAVTFQAFIDFMSSETTDKDSADQVIASFKILAGDKNYIMADELRRELPPDQAEYCIARMAPYTGPDGVPGA-LDYMSFSTALY 904

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Medaka
Match: ENSORLT00000001153.2 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 613.994 bits (1582), Expect = 0.000e+0
Identity = 344/917 (37.51%), Postives = 515/917 (56.16%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEE-----------------------NDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DY+SL       NL  AF +AEKHLD+P+ML+ +D+++    DE++IM YVSS+YHA    +K +TA   ICK+L+   E  Q   + + L+ NLL W+   I  L++R+Q      +  K  +F++YR   KP K ++K Q+          + L+ + +    +  + S + S W+ +E  E  YEE I  +  R + +++    F     +  +W + K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+TL  L   R + +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + +I  + G++    NPYT I  + +   W Q    +P+RDK L+  L KQ      +  F+K +  +        EE+  I   +   +   +T      + +Q  +     ++N L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD+ ++  L   +F++C++SLGY + ENE+                        D +F  IM +VDP N+G +T  +F+DF+  + +++  ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +G     LDY +FS  L+
Sbjct:   13 GGPQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYESLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASNLLEWIRRTIPWLEDRTQQKTVNDMQAKQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLSNRPAFMPSEGRMVSDINSAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTNGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSASVNNRCQKICDQWDTLGTLTHSRKDSLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLIAAHEQFKSTLPEANKEREAIQAIQAEVQKIAQSNGIKLSGANPYTTITPRSIDDKWEQAMAMVPQRDKALQGELNKQNSNDTLRATFAKQANVVGGYIQAKMEEIGRISIEMNGTLEDQLT----HLREYQQTILFFMPEINTLEGYHQHIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLYEYRASFNHFDKDHTGSLIAEEFKACLISLGYDV-ENEKQKRSGQMASDDFRALLISTGTSLGDAEFTRIMSIVDPNNSGAVTFQAFIDFMSSETTDKDSADQVIASFKILAGDKNYIMADELRRELPPDQAEYCIARMAPYTGPDGVPGA-LDYMSFSTALY 915

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Medaka
Match: ENSORLT00000001155.2 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 610.912 bits (1574), Expect = 0.000e+0
Identity = 340/894 (38.03%), Postives = 506/894 (56.60%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DY+SL       NL  AF +AEKHLD+P+ML+ +D++     DE++IM YVS +YHA    +K +TA   ICK+L+   E  Q   + + L+ NLL W+   I  L++R+Q      +  K  +F++YR   KP K ++K Q+          + L+ + +    +  + S + S W+ +E  E  YEE I  +  R + +++    F     +  +W + K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+TL  L   R + +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + +I  + G++    NPYT I  + +   W Q    +P+RDK L+  L KQ      +  F+K +  +        EE+  I   +   +   +T      + +Q  +     ++N L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD+  S ++    FR+ ++S G SL      D +F  IM +VDP N+G +T  +F+DF+  + +++  ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +G     LDY +FS  L+
Sbjct:   13 GGPQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYESLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVGTLRPDEKAIMTYVSCFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASNLLEWIRRTIPWLEDRTQQKTVNDMQAKQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLSNRPAFMPSEGRMVSDINSAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTNGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSASVNNRCQKICDQWDTLGTLTHSRKDSLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLIAAHEQFKSTLPEANKEREAIQAIQAEVQKIAQSNGIKLSGANPYTTITPRSIDDKWEQAMAMVPQRDKALQGELNKQNSNDTLRATFAKQANVVGGYIQAKMEEIGRISIEMNGTLEDQLT----HLREYQQTILFFMPEINTLEGYHQHIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLYEYRASFNHFDKKRSGQMASDDFRALLISTGTSL-----GDAEFTRIMSIVDPNNSGAVTFQAFIDFMSSETTDKDSADQVIASFKILAGDKNYIMADELRRELPPDQAEYCIARMAPYTGPDGVPGA-LDYMSFSTALY 888

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Medaka
Match: ENSORLT00000027622.1 (alpha-actinin-4 [Source:NCBI gene;Acc:101155449])

HSP 1 Score: 609.757 bits (1571), Expect = 0.000e+0
Identity = 343/917 (37.40%), Postives = 513/917 (55.94%), Query Frame = 1

Query:  169 GLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEE-----------------------NDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            G    Y ++++D + D+ +DP WE QQ  TFTAWCN+HLRKA  +I+N E DFR GLKLM LLE+IS + LP P++GKMR HKI NVNKAL FI  KGVKL SIGAEEIVDGN+KMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  YKN+ V+NF  S++DGL F ALI  H   L+DY+SL       NL  AF +AEKHLD+P+ML+ +D++     DE++IM YVS +YHA    +K +TA   ICK+L+   E  Q   + + L+ NLL W+   I  L++R+Q      +  K  +F++YR   KP K ++K Q+          + L+ + +    +  + S + S W+ +E  E  YEE I  +  R + +++    F     +  +W + K  +L  KDYET+ LSE+K L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+TL  L   R + +      L  ID+L LE+AKR  P  NW +  ++DL D F  H+ ++I+ LI A E FKST+ EA  E   ++++   + +I  + G++    NPYT I  + +   W Q    +P+RDK L+  L KQ      +  F+K +  +        EE+  I   +   +   +T      + +Q  +     ++N L+  +Q + E    DN  T Y+ E         L+ I  T+N + N+I       LT +   IS   ++ EY+  F +FD+ ++  L   +F++C++SLGY + ENE+                        D +F  IM +VDP N+G +T  +F+DF+  + +++  ++Q + SFKILA +++ I    + +ELP   A+YCI  M      +G     LDY +FS  L+
Sbjct:   13 GGPQTYMEQENDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNIKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPDLIDYESLRKDDPVTNLNNAFEVAEKHLDIPKMLDAEDIVGTLRPDEKAIMTYVSCFYHAFSGAQKAETAANRICKVLAVNQENEQMMEDYEKLASNLLEWIRRTIPWLEDRTQQKTVNDMQAKQEDFRDYRTVHKPPKVQEKCQLEISFNTLQTKLRLSNRPAFMPSEGRMVSDINSAWHTLEGAEKGYEEWILSEIRRLERLEHLAEKFHQKAAIHESWTNGKEAMLTQKDYETSTLSEVKALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYYDSASVNNRCQKICDQWDTLGTLTHSRKDSLERTEKQLESIDELYLEYAKRAAPFNNWMEGAMEDLQDMFIVHNIEEIQGLIAAHEQFKSTLPEANKEREAIQAIQAEVQKIAQSNGIKLSGANPYTTITPRSIDDKWEQAMAMVPQRDKALQGELNKQNSNDTLRATFAKQANVVGGYIQAKMEEIGRISIEMNGTLEDQLT----HLREYQQTILFFMPEINTLEGYHQHIQEALIFDNQYTSYTMEHLRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLYEYRASFNHFDKDHTGSLIAEEFKACLISLGYDV-ENEKQKRSGQMASDDFRALLISTGTSLGDAEFTRIMSIVDPNNSGAVTFQAFIDFMSSETTDKDSADQVIASFKILAGDKNYIMADELRRELPPDQAEYCIARMAPYTGPDGVPGA-LDYMSFSTALY 915

[Close]

BLAST of Actinin alpha 4 vs. Ensembl Medaka
Match: actn3b (actinin alpha 3 [Source:NCBI gene;Acc:101158802])

HSP 1 Score: 606.29 bits (1562), Expect = 0.000e+0
Identity = 339/878 (38.61%), Postives = 498/878 (56.72%), Query Frame = 1

Query:  229 PIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLA-------EELS----DIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQ--------LSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            P WE QQ  TFTAWCN+HLRKA  +I+N E DFR+GLKLM LLE+IS + LP PDKGKMRFHKIANVNKAL FI  KGVKL SIGAEEIVDGNVKMTLGMIWTIILRF IQ+I VE++SAKEGLLLWC+RKT  Y+N+ V+NF  S++DGL  CALI  H   L+DY  L       NL  AF +AEK LD+P+ML+ +D+++    DE++IM YVS +YHA    E+ +TA   ICK+L+   E  +     + L+  LL W+   I  L+NR        +  K+ +F++YR   KP + ++K Q+          + L+ + +    +  + S + + W  +E++E  YEE +  +  R + + +    F+    +  AW S K DLL  KDYE+A+L E++ L R  E F S++ +H+ R ++I  IA EL  L+Y D  ++  +   I + W+ L  L  +R + +         ID L LEFAKR  P  NW    ++DL D F  HS ++I+ LI A + FK+T+ EA  E      + + I +I    G++   +NPYT++  QD+   W  ++  +P RD+ L+E + +Q   +  +  F+  +  +        EE+S    DI  SL + M+S         + ++  +    S +++L+  +Q   E    DN  T YS E         L+ I  T+N + N+I       LT +   IS   ++ E++  F +FDR  +  +D   FR+C++S+GY L E E     F  IM LVDP NTG +T  +F+DF+ ++ +    +EQ + SFKILA++++ I    + +ELP   A+YCI  M   +  +      LDY +FS  L+
Sbjct:   38 PAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDKGKMRFHKIANVNKALDFICSKGVKLVSIGAEEIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHISWKDGLALCALIHRHRPDLIDYSKLRKDDPIGNLNTAFEVAEKFLDIPRMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENEKLMEEYEKLASELLEWIRRTIPWLENRVAEQTMRAMQQKLEDFRDYRRVHKPPRVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDIANAWKGLEQVEKGYEEWLLTEIRRLERLDHLAEKFKQKCAMHEAWTSGKEDLLSQKDYESASLMEIRALMRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAASVNARCQGICDQWDNLGTLTQKRRDALERVEKLWETIDQLYLEFAKRAAPFNNWMDGAMEDLQDMFIVHSIEEIQSLITAHDQFKATLPEADKERMATLGIHNEILKIAQTYGIKLSGINPYTNLSPQDISNKWDTVKHLVPLRDQMLQEEVARQQANERLRRQFAAQANIIGPWIQTKMEEISHVSVDIAGSLEEQMNS--------LKQYEQNIINYKSNIDKLEGDHQLSQESLIFDNKHTNYSMEHVRVGWEQLLTTIARTINEVENQI-------LTRDAKGIS-QEQLNEFRASFNHFDRKRNGMMDPDDFRACLISMGYDLGEVE-----FARIMTLVDPNNTGVVTFQAFIDFMTRETAETDTAEQVMASFKILASDKNYITVDELRRELPPEQAEYCISRMTRYVGPDAPPGA-LDYISFSSALY 893

[Close]

BLAST of Actinin alpha 4 vs. Planmine SMEST
Match: SMESG000074430.1 (SMESG000074430.1)

HSP 1 Score: 1860.88 bits (4819), Expect = 0.000e+0
Identity = 905/908 (99.67%), Postives = 906/908 (99.78%), Query Frame = 1

Query:   88 MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST 2811
            MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERK+KMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGE QNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPE TGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST
Sbjct:    1 MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKKKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGEFQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPEKTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST 908

[Close]

BLAST of Actinin alpha 4 vs. Planmine SMEST
Match: SMESG000074430.1 (SMESG000074430.1)

HSP 1 Score: 1844.32 bits (4776), Expect = 0.000e+0
Identity = 905/936 (96.69%), Postives = 906/936 (96.79%), Query Frame = 1

Query:   88 MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQ----------------------------KLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST 2811
            MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERK+KMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGE QNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQ                            KLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPE TGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST
Sbjct:    1 MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKKKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGEFQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQIMNEHSFECNAFPQLEILLLDDFCTIFRKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPEKTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST 936

[Close]

BLAST of Actinin alpha 4 vs. Planmine SMEST
Match: SMESG000074430.1 (SMESG000074430.1)

HSP 1 Score: 1752.26 bits (4537), Expect = 0.000e+0
Identity = 853/859 (99.30%), Postives = 854/859 (99.42%), Query Frame = 1

Query:  235 WEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST 2811
            WE QQ  TFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERK+KMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGE QNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPE TGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST
Sbjct:   18 WEKQQKVTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKKKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGEFQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPEKTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTSNTMLNGST 876

[Close]

BLAST of Actinin alpha 4 vs. Planmine SMEST
Match: SMESG000026000.1 (SMESG000026000.1)

HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0
Identity = 348/887 (39.23%), Postives = 524/887 (59.08%), Query Frame = 1

Query:  184 YFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQ-----TFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFE--------QLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            Y D D  +E    ID +WE QQ +TFTAWCN+HLRK +  I+  E+DFR GLKLM+LLE+IS + LP  DKGKMR HKIANVNK L FI +KGVKLA +G+EEIVDGNVKMTLGMIWTIILRF IQ+I +ED SAKEGLLLWC+RKT  YKN+KV NF  SF+DGL FCALI  H   L+DY++L       NL LAF +AEKHLD+P+ML+ +DMI     DE S+MAYVSSYYHA    +K +TA   ICK+L    E  +     + LS NLL W+E  I   Q+RS+      ++ K+ NF+ YR  +KP K+++K Q+          + L+ + +    +      +  +W ++E  E  +EE +  +  R + +   +  F +      +W + KI++L S+DY  ANL EL+ L +  + F S+   H+ R  +I  IA EL++L Y DM++I+ ++  I+  W+ +  L+ +R E I + L  L  ID L L+FAK+V  +YNW +Q  +DL D F  H  D++K L+     FK ++ +AT E   + +++ +I  +     L K   NPYT +  Q+++  W +L   +P+R K LKE L +Q   +  +  ++  + K+   L D ++   + +S+NV + + + Q       +  +     +  ELD  +Q+L ++   +N  T YS E         LS+I +T N + N+I    S  L+S Q        +EE++ CF +FD+ ++  L+ ++F++C++SLGY+L E+ + +  F  IM+ VDP N G++T  +F+DF+  + ++   S+Q + SFK+LA ++  I    + +ELP   A+YCI NM +  +  G + C  DY +FS  L+
Sbjct:   10 YVDPDYLEEQHDVIDLLWEKQQKTTFTAWCNSHLRKVNQNIEVIEQDFRDGLKLMQLLEVISGERLPKADKGKMRVHKIANVNKCLNFIAQKGVKLAYVGSEEIVDGNVKMTLGMIWTIILRFAIQDIKMEDLSAKEGLLLWCQRKTAPYKNVKVSNFHTSFKDGLAFCALIHRHRPDLIDYNNLHKDNARENLNLAFDVAEKHLDIPRMLDAEDMIKFAKPDELSVMAYVSSYYHAFSGAQKAETASNRICKVLGVNQENEKLMNEYETLSTNLLKWIEKMIPIFQDRSESTSVENMHNKLDNFRKYRITEKPPKHEEKGQLETAYNTLQTRLRLSNRPNFIPPESKTIGDINHRWKDLENSEKDFEEWLMSELQRLEQLDYLVRRFHLRCNTHESWSNGKIEMLQSEDYLNANLPELRALYKRLQAFESDFSGHEPRVVRINVIAEELRKLEYHDMKSIDARLNSIVETWDYMGKLDAERNENIKNILQLLENIDSLHLDFAKKVPNIYNWIEQAKEDLQDSFMVHYIDEVKALLDQHYQFKESLKDATSEYDELIAISKKIKSLAEEHNLGKAVENPYTMVTSQNLRDEWEELNSLVPKRGKELKEELTRQEQHENLRLKYANLANKVGPWL-DARQEKLNSLSNNVIQASLEEQKSELYKLEQEVMDFRPKAEELDQCSQELHKYLIFENRHTQYSMEIVRVSWEQLLSSIRKTRNEIDNQILTRDSKGLSSEQ--------MEEFRRCFNHFDKDHTKMLEPNEFKACLVSLGYNLKED-KGEADFSRIMLQVDPNNDGYVTFDAFIDFMTHETADEDSSDQMLRSFKVLAGDKDYITEEELRRELPKEQAEYCIANM-LPYTGPGGDVCGYDYQSFSNSLY 885

[Close]

BLAST of Actinin alpha 4 vs. Planmine SMEST
Match: SMESG000026000.1 (SMESG000026000.1)

HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0
Identity = 349/896 (38.95%), Postives = 526/896 (58.71%), Query Frame = 1

Query:  184 YFDEDSDKEFDIAIDPIWEAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPAPDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWTIILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVFCALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIHNKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINSDILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNKDKIQI----------MYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRYDLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAETFASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHLNCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFHSTDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPLNPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFSKKLAEELSDIQKSLFDMMSSNVTKRACKCQ-----TFQTRLNKCASQLNELDSINQKLDEHHKIDNFKTPYSFE--------QLSAIHETLNYLLNEISKSSSPNLTSNQSDISLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEEN---------DRQFKEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSAIKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLF 2775
            Y D D  +E    ID +WE QQ +TFTAWCN+HLRK +  I+  E+DFR GLKLM+LLE+IS + LP  DKGKMR HKIANVNK L FI +KGVKLA +G+EEIVDGNVKMTLGMIWTIILRF IQ+I +ED SAKEGLLLWC+RKT  YKN+KV NF  SF+DGL FCALI  H   L+DY++L       NL LAF +AEKHLD+P+ML+ +DMI     DE S+MAYVSSYYHA    +K +TA   ICK+L    E  +     + LS NLL W+E  I   Q+RS+      ++ K+ NF+ YR  +KP K+++K Q+          + L+ + +    +      +  +W ++E  E  +EE +  +  R + +   +  F +      +W + KI++L S+DY  ANL EL+ L +  + F S+   H+ R  +I  IA EL++L Y DM++I+ ++  I+  W+ +  L+ +R E I + L  L  ID L L+FAK+V  +YNW +Q  +DL D F  H  D++K L+     FK ++ +AT E   + +++ +I  +     L K   NPYT +  Q+++  W +L   +P+R K LKE L +Q   +  +  ++  + K+   L D ++   + +S+NV + + + Q       +  +     +  ELD  +Q+L ++   +N  T YS E         LS+I +T N + N+I    S  L+S Q        +EE++ CF +FD+ ++  L+ ++F++C++SLGY+L E+++N         +  F  IM+ VDP N G++T  +F+DF+  + ++   S+Q + SFK+LA ++  I    + +ELP   A+YCI NM +  +  G + C  DY +FS  L+
Sbjct:   10 YVDPDYLEEQHDVIDLLWEKQQKTTFTAWCNSHLRKVNQNIEVIEQDFRDGLKLMQLLEVISGERLPKADKGKMRVHKIANVNKCLNFIAQKGVKLAYVGSEEIVDGNVKMTLGMIWTIILRFAIQDIKMEDLSAKEGLLLWCQRKTAPYKNVKVSNFHTSFKDGLAFCALIHRHRPDLIDYNNLHKDNARENLNLAFDVAEKHLDIPRMLDAEDMIKFAKPDELSVMAYVSSYYHAFSGAQKAETASNRICKVLGVNQENEKLMNEYETLSTNLLKWIEKMIPIFQDRSESTSVENMHNKLDNFRKYRITEKPPKHEEKGQLETAYNTLQTRLRLSNRPNFIPPESKTIGDINHRWKDLENSEKDFEEWLMSELQRLEQLDYLVRRFHLRCNTHESWSNGKIEMLQSEDYLNANLPELRALYKRLQAFESDFSGHEPRVVRINVIAEELRKLEYHDMKSIDARLNSIVETWDYMGKLDAERNENIKNILQLLENIDSLHLDFAKKVPNIYNWIEQAKEDLQDSFMVHYIDEVKALLDQHYQFKESLKDATSEYDELIAISKKIKSLAEEHNLGKAVENPYTMVTSQNLRDEWEELNSLVPKRGKELKEELTRQEQHENLRLKYANLANKVGPWL-DARQEKLNSLSNNVIQASLEEQKSELYKLEQEVMDFRPKAEELDQCSQELHKYLIFENRHTQYSMEIVRVSWEQLLSSIRKTRNEIDNQILTRDSKGLSSEQ--------MEEFRRCFNHFDKDHTKMLEPNEFKACLVSLGYNLKEDKDNQHGRRASVGEADFSRIMLQVDPNNDGYVTFDAFIDFMTHETADEDSSDQMLRSFKVLAGDKDYITEEELRRELPKEQAEYCIANM-LPYTGPGGDVCGYDYQSFSNSLY 895

The following BLAST results are available for this feature:

BLAST of Actinin alpha 4 vs. Ensembl Human
BLAST of Actinin alpha 4 vs. Ensembl Celegans
BLAST of Actinin alpha 4 vs. Ensembl Fly
BLAST of Actinin alpha 4 vs. Ensembl Zebrafish
BLAST of Actinin alpha 4 vs. Ensembl Xenopus
BLAST of Actinin alpha 4 vs. Ensembl Mouse
BLAST of Actinin alpha 4 vs. UniProt/SwissProt
BLAST of Actinin alpha 4 vs. TrEMBL
BLAST of Actinin alpha 4 vs. Ensembl Cavefish
BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
BLAST of Actinin alpha 4 vs. Ensembl Yeast
BLAST of Actinin alpha 4 vs. Ensembl Nematostella
BLAST of Actinin alpha 4 vs. Ensembl Medaka
BLAST of Actinin alpha 4 vs. Planmine SMEST

BLAST of Actinin alpha 4 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ACTN2	0.000e+0	36.60	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]
ACTN2	0.000e+0	36.49	actinin alpha 2 [Source:HGNC Symbol;Acc:HGNC:164]	[more]
ACTN3	0.000e+0	36.82	actinin alpha 3 (gene/pseudogene) [Source:HGNC Sym...	[more]
ACTN1	0.000e+0	36.59	actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]	[more]
ACTN1	0.000e+0	36.70	actinin alpha 1 [Source:HGNC Symbol;Acc:HGNC:163]	[more]

BLAST of Actinin alpha 4 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
atn-1	0.000e+0	36.84	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
atn-1	0.000e+0	35.86	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
atn-1	1.951e-177	35.75	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
atn-1	1.702e-170	34.74	AcTiniN [Source:UniProtKB/TrEMBL;Acc:Q9XVU8]	[more]
unc-70	6.560e-75	33.33	Spectrin beta chain [Source:UniProtKB/TrEMBL;Acc:...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Actn	0.000e+0	37.44	gene:FBgn0000667 transcript:FBtr0333801	[more]
Actn	0.000e+0	37.44	gene:FBgn0000667 transcript:FBtr0070343	[more]
Actn	0.000e+0	37.44	gene:FBgn0000667 transcript:FBtr0303048	[more]
Actn	0.000e+0	37.33	gene:FBgn0000667 transcript:FBtr0070344	[more]
Actn	0.000e+0	37.24	gene:FBgn0000667 transcript:FBtr0310657	[more]

BLAST of Actinin alpha 4 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
actn4	0.000e+0	37.47	actinin, alpha 4 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]
actn4	0.000e+0	37.36	actinin, alpha 4 [Source:ZFIN;Acc:ZDB-GENE-030131-...	[more]
actn3a	0.000e+0	38.37	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]
actn3a	0.000e+0	38.37	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]
actn3a	0.000e+0	38.37	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gss	0.000e+0	38.26	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	0.000e+0	38.13	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	0.000e+0	38.00	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	0.000e+0	38.32	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]
gss	0.000e+0	37.70	glutathione synthetase [Source:Xenbase;Acc:XB-GENE...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Actn3	0.000e+0	37.25	actinin alpha 3 [Source:MGI Symbol;Acc:MGI:99678]	[more]
Actn2	0.000e+0	36.49	actinin alpha 2 [Source:MGI Symbol;Acc:MGI:109192]	[more]
Actn2	0.000e+0	36.49	actinin alpha 2 [Source:MGI Symbol;Acc:MGI:109192]	[more]
Actn1	0.000e+0	36.48	actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:213770...	[more]
Actn1	0.000e+0	36.59	actinin, alpha 1 [Source:MGI Symbol;Acc:MGI:213770...	[more]

BLAST of Actinin alpha 4 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q0III9\|ACTN3_BOVIN	0.000e+0	36.99	Alpha-actinin-3 OS=Bos taurus OX=9913 GN=ACTN3 PE=...	[more]
sp\|O88990\|ACTN3_MOUSE	0.000e+0	37.25	Alpha-actinin-3 OS=Mus musculus OX=10090 GN=Actn3 ...	[more]
sp\|P20111\|ACTN2_CHICK	0.000e+0	36.26	Alpha-actinin-2 OS=Gallus gallus OX=9031 GN=ACTN2 ...	[more]
sp\|P35609\|ACTN2_HUMAN	0.000e+0	36.49	Alpha-actinin-2 OS=Homo sapiens OX=9606 GN=ACTN2 P...	[more]
sp\|Q9JI91\|ACTN2_MOUSE	0.000e+0	36.49	Alpha-actinin-2 OS=Mus musculus OX=10090 GN=Actn2 ...	[more]

BLAST of Actinin alpha 4 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A3Q2DD20	0.000e+0	38.48	Actinin alpha 4 OS=Cyprinodon variegatus OX=28743 ...	[more]
A0A3B3XA06	0.000e+0	38.26	Actinin alpha 4 OS=Poecilia mexicana OX=48701 GN=A...	[more]
M3ZLS4	0.000e+0	38.26	Actinin alpha 4 OS=Xiphophorus maculatus OX=8083 G...	[more]
A0A4D9EY28	0.000e+0	39.26	Catenin alpha-3-like OS=Platysternon megacephalum ...	[more]
A0A4Z2C5U7	0.000e+0	38.12	Uncharacterized protein OS=Takifugu bimaculatus OX...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSAMXT00000048439.1	0.000e+0	37.79	pep primary_assembly:Astyanax_mexicanus-2.0:6:1768...	[more]
actn4	0.000e+0	36.91	actinin alpha 4 [Source:NCBI gene;Acc:103022122]	[more]
actn2b	0.000e+0	36.82	alpha-actinin-2 [Source:NCBI gene;Acc:103024106]	[more]
actn3a	0.000e+0	38.48	actinin alpha 3a [Source:ZFIN;Acc:ZDB-GENE-000329-...	[more]
actn1	0.000e+0	36.50	actinin alpha 1 [Source:NCBI gene;Acc:103031817]	[more]

BLAST of Actinin alpha 4 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000009295.1	0.000e+0	36.05	pep scaffold:Pmarinus_7.0:GL479988:2885:20778:1 ge...	[more]
ENSPMAT00000000684.1	5.353e-139	43.59	pep scaffold:Pmarinus_7.0:GL483163:49540:93186:-1 ...	[more]
ENSPMAT00000004049.1	4.370e-87	34.87	pep scaffold:Pmarinus_7.0:GL476488:489896:554954:1...	[more]
ENSPMAT00000008111.1	1.023e-77	33.26	pep scaffold:Pmarinus_7.0:GL478136:8967:48859:1 ge...	[more]
ENSPMAT00000001834.1	4.663e-63	30.93	pep scaffold:Pmarinus_7.0:GL482425:158920:175005:1...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
SAC6	1.368e-9	25.87	Fimbrin, actin-bundling protein; cooperates with S...	[more]
CMD1	7.506e-6	25.98	Calmodulin; Ca2+ binding protein that regulates Ca...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
ALPHA-ACTININ	0.000e+0	34.78	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO42431	3.512e-73	33.33	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49576	8.067e-69	32.84	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO29101	3.304e-63	39.68	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO37708	1.604e-45	37.27	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Actinin alpha 4 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSORLT00000001151.2	0.000e+0	37.79	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
ENSORLT00000001153.2	0.000e+0	37.51	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
ENSORLT00000001155.2	0.000e+0	38.03	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
ENSORLT00000027622.1	0.000e+0	37.40	alpha-actinin-4 [Source:NCBI gene;Acc:101155449]	[more]
actn3b	0.000e+0	38.61	actinin alpha 3 [Source:NCBI gene;Acc:101158802]	[more]

BLAST of Actinin alpha 4 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000074430.1	0.000e+0	99.67	SMESG000074430.1	[more]
SMESG000074430.1	0.000e+0	96.69	SMESG000074430.1	[more]
SMESG000074430.1	0.000e+0	99.30	SMESG000074430.1	[more]
SMESG000026000.1	0.000e+0	39.23	SMESG000026000.1	[more]
SMESG000026000.1	0.000e+0	38.95	SMESG000026000.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30035939 ID=SMED30035939|Name=Actinin alpha 4|organism=Schmidtea mediterranea sexual|type=transcript|length=3039bp
CTAAAAATTGGTGCTTCATGCATGCATATTAATAGACTCAACATCGATTT
AATATTTTGTTGAAGTTTCGTTCTTGAATTATTGAACATGTCGGAAAGAA
ATGAAGAAATTGATATTGTAAAAATGTGCCATGTAACCTCATCGAGTATG
GCCATAATGGATTTCGAGGGTTTGGGAAACGAATATTTTGATGAAGATTC
TGACAAAGAATTCGACATTGCAATCGATCCAATTTGGGAAGCACAACAAA
TATCGACATTTACTGCATGGTGTAATGCCCATTTAAGGAAAGCTAGCATG
AAAATTGACAATTTTGAACGAGATTTTAGGAGTGGCTTAAAACTAATGAA
ATTACTGGAAATAATAAGCAATGATAATCTACCTGCTCCAGACAAAGGAA
AAATGAGATTTCATAAAATTGCCAATGTTAATAAGGCATTGAAGTTTATT
GAAGAAAAAGGTGTTAAATTAGCATCCATCGGTGCCGAAGAAATTGTTGA
TGGCAATGTTAAAATGACACTGGGAATGATATGGACAATAATTTTGCGGT
TCACTATTCAGAATATTTTGGTTGAAGATTCATCTGCAAAAGAGGGACTT
TTACTATGGTGCAAACGAAAAACTAATGGATACAAAAATATCAAAGTTGA
AAATTTCAAAAATAGTTTCCAGGATGGCTTAGTTTTTTGTGCTCTAATTG
ATAGCCATGATAAGTCATTGCTTGATTACGATTCTCTTTCACCAAGCCAA
ATTTCACATAATCTTAAACTCGCTTTCACCTTAGCTGAGAAGCACCTCGA
TGTTCCACAAATGTTAAATATTGATGACATGATTCATAACAAAGATTCCG
ATGAGCGTTCCATTATGGCGTACGTTTCGTCGTATTATCATGCTATTGAG
CGGAAGGAAAAGATGGATACAGCGTTGAAAAACATTTGCAAAATCCTGTC
TCAGGAAATGGAAGAAAGTCAACATTCCATAAACAGTGATATATTATCCA
AAAATTTGTTGAATTGGGTTGAACATTGGATAGGAGAATTGCAGAATCGC
TCTCAATTGGATGATCAAACAACTTTGAATGTTAAAATCAGTAACTTTAA
AAATTATAGGTTTTATGATAAGCCAGAAAAAAATAAAGATAAAATACAAA
TAATGTATCTGAATCTTAAAAAATCAACCGAAAAGAAGAAGTTCAATATT
TGTTCGACTGTCCAATCGAAATGGAATGAAATGGAAAAATTGGAAAATCA
TTATGAGGAGCATATATCTGAGCAAAAGTATAGGTATGATCTTATTCAAA
ACTTTCTCAATAGTTTCGAGATCAATTTCCAAGTTCAAAGAGCTTGGATT
AGTAACAAAATTGATCTACTCGTTTCCAAAGATTATGAAACAGCAAATTT
GAGTGAATTGAAAAAGTTACAACGGGCAGCTGAAACTTTTGCATCAAATG
TCGGCTCTCACAAAGCTAGGAACGATAAAATTGTCAATATTGCTGCTGAA
TTGAAGCGACTTAATTATAAAGACATGGAAACTATTGAAAAGAAAGTTAC
AATTATACTCAATCCTTGGGAAACCCTCTATCATCTGAATTGTCAACGAA
TAGAGAGAATTAATAGTTTTCTTCATGCATTAACAGAAATAGACGACTTG
CAATTAGAATTTGCCAAAAGAGTCATGCCTCTTTACAATTGGAATCAACA
AGTTATTCAAGATTTGAATGACAGATTTACTTTTCATTCTACAGACGATA
TAAAAGATTTGATCAAAGCTCAGGAGATTTTTAAATCAACAGTAGATGAA
GCGACGGATGAATTAACTTATGTGAAATCGCTAACCGACAGAATTTGTAG
AATCGTCACTGCTACCGGGTTGCAAAAAATACCATTAAATCCTTATACTG
ATATAATGTTACAGGATGTGCAAAAAGCATGGATCCAGTTAGAAAGAAGT
ATTCCTGAAAGAGACAAAACTTTGAAAGAAGCTCTTATTAAACAAATAGG
ACTGAAAGAGTGCAAAGATAATTTTTCAAAATTTTCTAAGAAACTTGCTG
AAGAATTGTCAGACATACAGAAAAGTCTGTTTGATATGATGTCATCAAAT
GTGACAAAAAGGGCATGTAAATGCCAAACATTTCAAACAAGACTCAATAA
ATGTGCTTCTCAGTTAAATGAACTGGACTCCATAAATCAAAAACTCGATG
AACATCATAAAATCGACAATTTTAAAACTCCTTACAGTTTCGAACAATTA
AGTGCAATACATGAGACATTGAATTATTTATTGAATGAGATTTCCAAGTC
CTCAAGTCCAAATCTGACAAGTAATCAGTCAGATATTTCATTGTCTAACA
AAGTTGAGGAATATAAGACTTGTTTTAAATATTTCGATCGCACGAATTCT
AATAAATTGGACCAAAGTCAGTTTCGTTCATGTATGTTGTCGTTAGGATA
TTCTCTCGATGAGAATGAAGAAAACGACAGACAATTTAAAGAAATAATGA
TGCTAGTTGATCCTGAAAATACGGGATTTATAACCCTTACTTCATTTCTG
GATTTCATCATTCAAAAAAATTCCAACCGGGGAATCAGCGAGCAGTTTGT
CGAATCATTTAAAATTTTAGCTAATAATCAGAGTGCAATCAAGCGTGCAA
CTATTCTCCAAGAACTACCGGATGCGATTGCCAAATATTGCATTGAAAAT
ATGCCAGTGAAAATATCATCAAATGGTGACAATGAATGCTATCTTGATTA
TTGCACATTTAGTGAGAAATTATTCCACAGCACATCCAATACAATGTTAA
ATGGCTCAACATAATATTTATTATCTCTGAACCAATATACCTTATATCTG
ACAGAGTTTATGCCAATTTGAAGAGATTTCAAATTTTCTCTTTGTAATTT
ATTTACTTCGCGAAATTTAGTAAAAAAATACTTATCTTCTACAGAGAAAA
TTATGAAGAATAATATATCGTGAAAATATTATTTTGTTTCCAATGTATTT
ATTGTCTTATGATTATTTTACCATATTTATAGCATATTA

protein sequence of SMED30035939-orf-1

>SMED30035939-orf-1 ID=SMED30035939-orf-1|Name=SMED30035939-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=99bp
MLAFLKWALHHAVNVDICCASQIGSIAMSNSLSESSSKYSFPKPSKSIMA
ILDEVTWHIFTISISSFLSDMFNNSRTKLQQNIKSMLSLLICMHEAPIF

protein sequence of SMED30035939-orf-2

>SMED30035939-orf-2 ID=SMED30035939-orf-2|Name=SMED30035939-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=909bp
MSERNEEIDIVKMCHVTSSSMAIMDFEGLGNEYFDEDSDKEFDIAIDPIW
EAQQISTFTAWCNAHLRKASMKIDNFERDFRSGLKLMKLLEIISNDNLPA
PDKGKMRFHKIANVNKALKFIEEKGVKLASIGAEEIVDGNVKMTLGMIWT
IILRFTIQNILVEDSSAKEGLLLWCKRKTNGYKNIKVENFKNSFQDGLVF
CALIDSHDKSLLDYDSLSPSQISHNLKLAFTLAEKHLDVPQMLNIDDMIH
NKDSDERSIMAYVSSYYHAIERKEKMDTALKNICKILSQEMEESQHSINS
DILSKNLLNWVEHWIGELQNRSQLDDQTTLNVKISNFKNYRFYDKPEKNK
DKIQIMYLNLKKSTEKKKFNICSTVQSKWNEMEKLENHYEEHISEQKYRY
DLIQNFLNSFEINFQVQRAWISNKIDLLVSKDYETANLSELKKLQRAAET
FASNVGSHKARNDKIVNIAAELKRLNYKDMETIEKKVTIILNPWETLYHL
NCQRIERINSFLHALTEIDDLQLEFAKRVMPLYNWNQQVIQDLNDRFTFH
STDDIKDLIKAQEIFKSTVDEATDELTYVKSLTDRICRIVTATGLQKIPL
NPYTDIMLQDVQKAWIQLERSIPERDKTLKEALIKQIGLKECKDNFSKFS
KKLAEELSDIQKSLFDMMSSNVTKRACKCQTFQTRLNKCASQLNELDSIN
QKLDEHHKIDNFKTPYSFEQLSAIHETLNYLLNEISKSSSPNLTSNQSDI
SLSNKVEEYKTCFKYFDRTNSNKLDQSQFRSCMLSLGYSLDENEENDRQF
KEIMMLVDPENTGFITLTSFLDFIIQKNSNRGISEQFVESFKILANNQSA
IKRATILQELPDAIAKYCIENMPVKISSNGDNECYLDYCTFSEKLFHSTS
NTMLNGST*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000099	neuron
PLANA:0002089	reproductive organ
PLANA:0003116	parenchymal cell
PLANA:0007528	glial cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036872	CH_dom_sf
IPR001715	CH-domain
IPR002048	EF_hand_dom
IPR011992	EF-hand-dom_pair
IPR002017	Spectrin_repeat
IPR014837	EF-hand_Ca_insen
IPR001589	Actinin_actin-bd_CS

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005509	calcium ion binding
GO:0003779	actin binding
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding
GO:0008092	cytoskeletal protein binding
GO:0019904	protein domain specific binding
GO:0030274	LIM domain binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375	thyroid hormone receptor coactivator activity
GO:0031432	titin binding
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0044325	ion channel binding
GO:0046872	metal ion binding
GO:0046983	protein dimerization activity
GO:0051015	actin filament binding
GO:0051373	FATZ binding
GO:0070080	titin Z domain binding

Vocabulary: **cellular component**
Term	Definition
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005925	focal adhesion
GO:0030017	sarcomere
GO:0030018	Z disc
GO:0030175	filopodium
GO:0070062	extracellular exosome

Vocabulary: **biological process**
Term	Definition
GO:0006936	muscle contraction
GO:0030035	microspike assembly
GO:0042391	regulation of membrane potential
GO:0043267	negative regulation of potassium ion transport
GO:0043268	positive regulation of potassium ion transport
GO:0045214	sarcomere organization
GO:0048041	focal adhesion assembly
GO:0051289	protein homotetramerization
GO:0051695	actin filament uncapping
GO:0055013	cardiac muscle cell development
GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway
GO:0090002	establishment of protein localization to plasma membrane
GO:1901017	negative regulation of potassium ion transmembrane transporter activity
GO:1901018	positive regulation of potassium ion transmembrane transporter activity
GO:1903506	regulation of nucleic acid-templated transcription
GO:2000009	negative regulation of protein localization to cell surface
GO:2000273	positive regulation of signaling receptor activity
GO:2001137	positive regulation of endocytic recycling
GO:2001259	positive regulation of cation channel activity

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR002048	EF-hand domain	SMART	SM00054	efh_1	coord: 799..827 e-value: 1.5 score: 16.3 coord: 758..786 e-value: 6.5 score: 11.2
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 795..830 score: 9.688
IPR002048	EF-hand domain	PROSITE	PS50222	EF_HAND_2	coord: 754..789 score: 10.413
IPR001715	Calponin homology domain	SMART	SM00033	ch_5	coord: 167..266 e-value: 1.2E-13 score: 61.3 coord: 54..154 e-value: 1.4E-24 score: 97.7
IPR001715	Calponin homology domain	PFAM	PF00307	CH	coord: 166..270 e-value: 1.4E-21 score: 76.7 coord: 54..156 e-value: 1.7E-22 score: 79.7
IPR001715	Calponin homology domain	PROSITE	PS50021	CH	coord: 165..271 score: 21.804
IPR001715	Calponin homology domain	PROSITE	PS50021	CH	coord: 52..156 score: 23.803
IPR001715	Calponin homology domain	CDD	cd00014	CH	coord: 166..269 e-value: 9.82479E-15 score: 68.8767
IPR001715	Calponin homology domain	CDD	cd00014	CH	coord: 54..155 e-value: 1.92391E-21 score: 88.1367
None	No IPR available	SMART	SM01184	efhand_Ca_insen_2	coord: 830..897 e-value: 1.5E-6 score: 37.7
None	No IPR available	GENE3D	G3DSA:1.20.58.60		coord: 402..512 e-value: 5.0E-12 score: 48.0
None	No IPR available	GENE3D	G3DSA:1.20.58.60		coord: 643..739 e-value: 3.8E-5 score: 25.9
None	No IPR available	GENE3D	G3DSA:1.20.58.60		coord: 278..400 e-value: 6.0E-9 score: 37.7
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 751..830 e-value: 1.0E-11 score: 46.7
None	No IPR available	GENE3D	G3DSA:1.20.58.60		coord: 513..637 e-value: 4.7E-27 score: 96.7
None	No IPR available	GENE3D	G3DSA:1.10.238.10		coord: 833..900 e-value: 3.3E-10 score: 42.0
None	No IPR available	PANTHER	PTHR11915:SF429	ALPHA-ACTININ-2	coord: 25..897
None	No IPR available	PANTHER	PTHR11915	SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN	coord: 25..897
None	No IPR available	CDD	cd00176	SPEC	coord: 419..633 e-value: 9.75899E-12 score: 63.2336
None	No IPR available	SUPERFAMILY	SSF46966	Spectrin repeat	coord: 305..395
None	No IPR available	SUPERFAMILY	SSF46966	Spectrin repeat	coord: 514..633
None	No IPR available	SUPERFAMILY	SSF46966	Spectrin repeat	coord: 373..508
IPR002017	Spectrin repeat	PFAM	PF00435	Spectrin	coord: 417..507 e-value: 6.4E-8 score: 33.0 coord: 522..631 e-value: 9.5E-6 score: 26.1
IPR014837	EF-hand, Ca insensitive	PFAM	PF08726	EFhand_Ca_insen	coord: 834..896 e-value: 5.7E-7 score: 29.5
IPR036872	CH domain superfamily	GENE3D	G3DSA:1.10.418.10		coord: 41..162 e-value: 8.5E-41 score: 140.7
IPR036872	CH domain superfamily	GENE3D	G3DSA:1.10.418.10		coord: 163..277 e-value: 1.3E-41 score: 143.0
IPR036872	CH domain superfamily	SUPERFAMILY	SSF47576	Calponin-homology domain, CH-domain	coord: 45..271
IPR001589	Actinin-type actin-binding domain, conserved site	PROSITE	PS00019	ACTININ_1	coord: 54..63
IPR001589	Actinin-type actin-binding domain, conserved site	PROSITE	PS00020	ACTININ_2	coord: 128..152
IPR011992	EF-hand domain pair	SUPERFAMILY	SSF47473	EF-hand	coord: 755..894