Abelson helper integration site 1

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVF-WWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFN----GHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  VL + IHRTDRLK+D  + HPM+++H++D  TG+ + K +  R V+S  E  E V  ILP+MTQP+DFK  +  +P WEE I+FNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P+ SP S    F WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P        +  VD+  PGL  +K      + +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++      P+  F     GH  II++L+W      + ++S+DGT ++W          KN  N  TNT               R L HP FVY   FHP V  +++T  YD +IRIW + + +    ++ Q D HK FIN   F  +G  +YSGD  G I  W+    ++ +       WT    I E + KG+ I++L +HP GKRL +H++D ++R++DL+I  +  KF G  N  + +   L+PCG+FLF+GSED      VYVWN +TG+ VA+Y +L    P+  I YHP  +++AF A G    I +Y Y+
Sbjct:  335 PKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEK-ENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPR-SPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEEKGKPVHCERHHESSSVDTE-PGLEESKE-----VIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEI------PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW----------KNEIN-NTNTF--------------RVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNT-YVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHSTLTPCGTFLFAGSED----GIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYD 919          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVF-WWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFN----GHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  VL + IHRTDRLK+D  + HPM+++H++D  TG+ + K +  R V+S  E  E V  ILP+MTQP+DFK  +  +P WEE I+FNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P+ SP S    F WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P        +  VD+  PGL  +K      + +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++      P+  F     GH  II++L+W      + ++S+DGT ++W          KN  N  TNT               R L HP FVY   FHP V  +++T  YD +IRIW + + +    ++ Q D HK FIN   F  +G  +YSGD  G I  W+    ++ +       WT    I E + KG+ I++L +HP GKRL +H++D ++R++DL+I  +  KF G  N  + +   L+PCG+FLF+GSED      VYVWN +TG+ VA+Y +L    P+  I YHP  +++AF A G    I +Y Y+
Sbjct:  335 PKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEK-ENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPR-SPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEEKGKPVHCERHHESSSVDTE-PGLEESKE-----VIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEI------PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW----------KNEIN-NTNTF--------------RVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNT-YVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHSTLTPCGTFLFAGSED----GIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYD 919          

Query: 2654 TSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTSGP---EDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            ++++  +   L TVTEV R+  A            + N N  +TS P     + +L +S+    T Q I      T T   +   KP     H+   +     VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++GY PAN+VA E L  E P   +E     SP   TK
Sbjct:  973 STKMQLVKQRLETVTEVIRSCAA------------KVNKNLSFTSPPAVSSQQSKLKQSNML--TAQEILHQFGFTQTGIISIERKP---CNHQ---VDTAPTVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTK 1133          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVF-WWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFN----GHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  VL + IHRTDRLK+D  + HPM+++H++D  TG+ + K +  R V+S  E  E V  ILP+MTQP+DFK  +  +P WEE I+FNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P+ SP S    F WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P        +  VD+  PGL  +K      + +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++      P+  F     GH  II++L+W      + ++S+DGT ++W          KN  N  TNT               R L HP FVY   FHP V  +++T  YD +IRIW + + +    ++ Q D HK FIN   F  +G  +YSGD  G I  W+    ++ +       WT    I E + KG+ I++L +HP GKRL +H++D ++R++DL+I  +  KF G  N  + +   L+PCG+FLF+GSED      VYVWN +TG+ VA+Y +L    P+  I YHP  +++AF A G    I +Y Y+
Sbjct:  335 PKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEK-ENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPR-SPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEEKGKPVHCERHHESSSVDTE-PGLEESKE-----VIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEI------PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW----------KNEIN-NTNTF--------------RVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNT-YVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHSTLTPCGTFLFAGSED----GIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYD 919          

Query: 2654 TSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTSGP---EDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            ++++  +   L TVTEV R+  A            + N N  +TS P     + +L +S+    T Q I      T T   +   KP     H+   +     VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++GY PAN+VA E L  E P   +E     SP   TK
Sbjct:  973 STKMQLVKQRLETVTEVIRSCAA------------KVNKNLSFTSPPAVSSQQSKLKQSNML--TAQEILHQFGFTQTGIISIERKP---CNHQ---VDTAPTVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTK 1133          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVF-WWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFN----GHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  VL + IHRTDRLK+D  + HPM+++H++D  TG+ + K +  R V+S  E  E V  ILP+MTQP+DFK  +  +P WEE I+FNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P+ SP S    F WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P        +  VD+  PGL  +K      + +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++      P+  F     GH  II++L+W      + ++S+DGT ++W          KN  N  TNT               R L HP FVY   FHP V  +++T  YD +IRIW + + +    ++ Q D HK FIN   F  +G  +YSGD  G I  W+    ++ +       WT    I E + KG+ I++L +HP GKRL +H++D ++R++DL+I  +  KF G  N  + +   L+PCG+FLF+GSED      VYVWN +TG+ VA+Y +L    P+  I YHP  +++AF A G    I +Y Y+
Sbjct:  335 PKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEK-ENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPR-SPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEEKGKPVHCERHHESSSVDTE-PGLEESKE-----VIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEI------PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW----------KNEIN-NTNTF--------------RVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNT-YVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHSTLTPCGTFLFAGSED----GIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYD 919          

Query: 2654 TSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTSGP---EDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            ++++  +   L TVTEV R+  A            + N N  +TS P     + +L +S+    T Q I      T T   +   KP     H+   +     VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++GY PAN+VA E L  E P   +E     SP   TK
Sbjct:  973 STKMQLVKQRLETVTEVIRSCAA------------KVNKNLSFTSPPAVSSQQSKLKQSNML--TAQEILHQFGFTQTGIISIERKP---CNHQ---VDTAPTVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTK 1133          

Query: 1072 PHRPKNSPYSSNVVF-WWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFN----GHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P +P+ SP S    F WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P        +  VD+  PGL  +K +      +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++      P+  F     GH  II++L+W      + ++S+DGT ++W          KN  N  TNT               R L HP FVY   FHP V  +++T  YD +IRIW + + +    ++ Q D HK FIN   F  +G  +YSGD  G I  W+    ++ +       WT    I E + KG+ I++L +HP GKRL +H++D ++R++DL+I  +  KF G  N  + +   L+PCG+FLF+GSED      VYVWN +TG+ VA+Y +L    P+  I YHP  +++AF A G    I +Y Y+
Sbjct:    2 PTKPR-SPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEEKGKPVHCERHHESSSVDTE-PGLEESKEV-----IKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEI------PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW----------KNEIN-NTNTF--------------RVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNT-YVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHSTLTPCGTFLFAGSED----GIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYD 419          

Query: 2654 TSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTSGP---EDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            ++++  +   L TVTEV R+  A            + N N  +TS P     + +L +S+    T Q I      T T   +   KP     H+  +      VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++GY PAN+VA E L  E P   +E     SP   TK
Sbjct:  473 STKMQLVKQRLETVTEVIRSCAA------------KVNKNLSFTSPPAVSSQQSKLKQSNML--TAQEILHQFGFTQTGIISIERKP---CNHQVDTAP---TVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTK 633          

Query: 1519 TFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTI--EADTVPVGGSFGDK-------------RTL-CHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGS-FLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            T  GH + I +  +    + L ++SAD T K+W M  +  E+         N I   +D+  V  +  DK             +TL  H  +V+   F+P  +S++++  +D+ +RIWD+       I  L  H   ++   F+ DG  + SG   G +  W              +    Q +   +D +   +  +   P GK +   + D +++L D      + ++ G  NS+  +    S  G  ++ SGSEDC    ++Y+WN QT + V   +  G + PV + D HP  ++IA  A+  ++ I I+
Sbjct:   82 TLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNP-QSSLVVSGSFDESVRIWDVKTGM--CIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIW--------------DTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDC----KIYIWNLQTREIVQCLE--GHTQPVLASDCHPVQNIIASGALEPDNKIHIW 372          

Query: 1519 TFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTI--EADTVPVGGSFGDK-------------RTL-CHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGS-FLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            T  GH + I +  +    + L ++SAD T K+W M  +  E+         N I   +D+  V  +  DK             +TL  H  +V+   F+P  +S++++  +D+ +RIWD+       I  L  H   ++   F+ DG  + SG   G +  W              +    Q +   +D +   +  +   P GK +   + D +++L D      + ++ G  NS+  +    S  G  ++ SGSEDC    ++Y+WN QT + V   +  G + PV + D HP  ++IA  A+  ++ I I+
Sbjct:   82 TLEGHTKSISSAKFSPCGKYLGTSSADKTVKIWNMDHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSRMTKTLKGHNNYVFCCNFNP-QSSLVVSGSFDESVRIWDVKTGM--CIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIW--------------DTANGQCIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDC----KIYIWNLQTREIVQCLE--GHTQPVLASDCHPVQNIIASGALEPDNKIHIW 372          

Query: 1345 MCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGS-FLFSGSEDCSSGSQVYVWNAQTGDHVAIYKEL-GLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNS 2421
            +  IPN  H K  +G      + FSPDG ++  G+ +           + ++      T  GH   I+  +W   S+L+ S S D   KV+ +             +   T++                 H  +V+   F+P   +++ +  +D+ IRIW       + I  + GH+  ++   F+ DG  L SG   G +  W              +  T   V   +D +   I H+   P GK +   + + +++L D +   ++ ++ G  NS+  +    S  G  ++ SGSED     +VY+WN QT +   I + L G +  V   D HP  ++IA  A+  +  I+I+   S
Sbjct:   99 VAEIPNA-HKKSISG------IKFSPDGRYMGSGSAD-------CSIKIWRMDFVYEKTLMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSS----------GRCVKTLKG----------------HTNYVFCCCFNP-SGTLIASGSFDETIRIW--CARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIW--------------DSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSED----HKVYIWNLQTRE---ILQTLDGHNTAVMCTDCHPGQNIIASAALEPDMRIKIWRSQS 395          

Query: 1510 PTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNA 2277
            P     GH   I +++W  K+  + S+  D T K+W + +                                 LC   H  FV  VAF P  +   ++   D  +R+W I   K  + +  D  K +I    F   G+    G   G   C      +LK       + T        + +G  +  L  H  G +L V S D  IR+ D++ KA+  KF G+ N    +R   SP G  +  GSED      VY+W A
Sbjct:  709 PFALLKGHTADILDVSWS-KNYFILSSGMDRTVKLWHLSR------------------------------NECLCCFQHIDFVTCVAFLPKDDRYFLSGSLDGKLRMWHIPDKKVAVWN--DTEKKYITAMTFVKSGKFAVVGTYDGK--CIFYTSDQLKYHTAVDVRSTRGK-----NARGHKVTGLTSH--GDKLLVTSNDSRIRMYDIRDKALTCKFKGVQNDHSQIRAAFSPDGRHIICGSED----KFVYIWRA 921          

Query: 1510 PTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNA 2277
            P     GH   I +++W  K+  + S+  D T K+W + +                                 LC   H  FV  VAF P  +   ++   D  +R+W I   K  + +  D  K +I    F   G+    G   G   C      +LK       + T        + +G  +  L  H  G +L V S D  IR+ D++ KA+  KF G+ N    +R   SP G  +  GSED      VY+W A
Sbjct:  709 PFALLKGHTADILDVSWS-KNYFILSSGMDRTVKLWHLSR------------------------------NECLCCFQHIDFVTCVAFLPKDDRYFLSGSLDGKLRMWHIPDKKVAVWN--DTEKKYITAMTFVKSGKFAVVGTYDGK--CIFYTSDQLKYHTAVDVRSTRGK-----NARGHKVTGLTSH--GDKLLVTSNDSRIRMYDIRDKALTCKFKGVQNDHSQIRAAFSPDGRHIICGSED----KFVYIWRA 921          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            + + FSP+G WLA  + +       L+            T +GH   I ++AW   S LL S S D T KVW +    S K          T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN Q+ +   + K  G +  V     HP  ++IA  A+ N+ +I+++
Sbjct:   76 SAVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLK----------TLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVRTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NMVYIWNLQSKE--VVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLW 357          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            + + FSP+G WLA  + +       L+            T +GH   I ++AW   S LL S S D T KVW +    S K          T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN Q+ +   + K  G +  V     HP  ++IA  A+ N+ +I+++
Sbjct:   76 SAVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLK----------TLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVRTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NMVYIWNLQSKE--VVQKLQGHTDTVLCTACHPTENIIASAALENDKTIKLW 357          

Query: 1510 PTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSED-CSSGSQVYVW 2271
            P  T+NGH   + +++W  K+  + S+S D T ++W + +                              K  LC   H  FV A+AFHP  +   ++   D  +R+W+I   K  + +++DG    I  A F  +G+    G   G    ++  + +   +   +       +       G  I+ +   P   ++ V S D  +RL DL+   +  K+ G +N    ++   S  G ++ +GSE+ C     +Y+W
Sbjct:  771 PFCTYNGHTSDLLDVSWS-KNYFILSSSMDKTVRLWHISR------------------------------KECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGQFAVVGSYDGRCIFYNTDQLKYHTQIHVRSTRGKNRI-------GRKISGIEPMPGEDKILVTSNDSRVRLYDLRDLNLSCKYKGYLNVSSQIKGSFSHDGKYIIAGSENQC-----IYIW 985          

Query: 1504 HHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFEL-----KNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLK 2136
            + P  TF GH   ++ + WC + +LLAS S D T K+W M +     D    ++   TI+      G                    +P  N IL +A +D  +R+WD  + +   IH L  H   +    FS DG+ L SG     +H WS    +L         IF+  W S+                     G ++   + DGS+ ++DL+
Sbjct:  524 NEPIKTFKGHTNEVNAIKWCPQGQLLASCSDDMTLKIWSMNRDRCCHDLQAHSKEIYTIKWSPTGPG------------------TNNPNTNLILASASFDSTVRLWD--VERGSCIHTLTKHTEPVYSVAFSPDGKHLASGSFDKCVHIWSTQTGQLVHSYKGTGGIFEVCWNSK---------------------GTKVGASASDGSVFVLDLR 698          

Query: 1510 PTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSED-CSSGSQVYVW 2271
            P  T+NGH   + +++W  K+  + S+S D T ++W + +                              K  LC   H  FV A+AFHP  +   ++   D  +R+W+I   K  + +++DG    I  A F  +G+    G   G    ++  + +   +   +       +       G  I+ +   P   ++ V S D  +RL DL+   +  K+ G +N    ++   S  G ++ +GSE+ C     +Y+W
Sbjct:  789 PFCTYNGHTSDLLDVSWS-KNYFILSSSMDKTVRLWHISR------------------------------KECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGQFAVVGSYDGRCIFYNTDQLKYHTQIHVRSTRGKNRI-------GRKISGIEPMPGEDKILVTSNDSRVRLYDLRDLNLSCKYKGYLNVSSQIKGSFSHDGKYIIAGSENQC-----IYIW 1003          

Query:  592 DDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNK-----HLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISIN--KKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            DD  VL + IHRTD+LKTDL V HPM++VH++D  TG+ + K++  R V+S  E  E +  ILP++TQPFDFK  + T+P WEE IIFNE   Y ++     P V+  FE+LD            V +   GF  IAWAFL+ + +NG LN   K+RLQLY   P R K  P +  V  WW +  R  Y STLYVT+ G+K  P    +  +RSM   Q+E        S L     NK         +   +W R+P Q+C IPN P   F  G  G  TL FS DG  LA  A  + + FP+++Y++   S    ++FNGH  ++++L W    + L +AS+DGT +VW ++++ +   K                         TL HP FVY   FHP   S++ T GYD ++R+W++ +      ++ + DGHK FIN   F  +G  ++S D  G I  W               +W+ +  I E DL G+ IN L +HP G+RL +H++D  +R++DL+I A V K+ G  N    +    +PCGSF+F+GSED       YVWN++TGD VA+Y EL  S  + ++ +HP  +++AF   G    I +Y Y+
Sbjct:  277 DDSLVLGVYIHRTDKLKTDLMVSHPMVKVHVVDEVTGQYVKKEDSHRHVSSFYEQ-ENIEHILPIITQPFDFKKHKTTVPEWEEQIIFNERFGYFLQDDDESPRVMLLFEILDFISMEEARTNVSVDRHERGFRKIAWAFLKLVGTNGVLNIDTKLRLQLY-CPPPRAKKVPQTVEVFQWWSKYPRNKYTSTLYVTVKGLK--PPEHVDPGIRSMMALQQERGSTSY--SELNSEMTNKTSTQIQESKAETMKWSRMPGQVCRIPNKPMHSFRGGQMGCFTLCFSHDGRALAA-ACADRDAFPIIIYEIP--SGKVLSSFNGHLSVVYDLCWSRDDKGLLTASSDGTVRVWNVERLQTLAHK-------------------------TLPHPSFVYCAKFHPQAQSLVATGGYDGVLRVWNVDVQDVNGQLLQEFDGHKTFINTLCFDPEGSRMFSADNSGLIIVWGTKVMPGSRRGA-TSQWSIEREIKEADLNGISINSLEVHPNGRRLLIHAKDSVLRVMDLRILA-VKKYIGATNYRDRINSTFTPCGSFIFAGSED----GLAYVWNSETGDQVAVYSELCYSSALRAVAFHPHENMVAFCCFGQNQPIHLYLYD 856          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGE 3115
            VV+LY+Y+A RSDE+S  RG+++ ++++D  +W  G    G++GY PA+YVA E
Sbjct: 1027 VVSLYEYRANRSDELSMRRGDVVHVLYKDNDSWWFGRLVSGQEGYFPASYVADE 1080          

Query:  592 DDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNK-----HLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISIN--KKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            DD  VL + IHRTD+LKTDL V HPM++VH++D  TG+ + K++  R V+S  E  E +  ILP++TQPFDFK  + T+P WEE IIFNE   Y ++     P V+  FE+LD            V +   GF  IAWAFL+ + +NG LN   K+RLQLY   P R K  P +  V  WW +  R  Y STLYVT+ G+K  P    +  +RSM   Q+E        S L     NK         +   +W R+P Q+C IPN P   F  G  G  TL FS DG  LA  A  + + FP+++Y++   S    ++FNGH  ++++L W    + L +AS+DGT +VW ++++ +   K                         TL HP FVY   FHP   S++ T GYD ++R+W++ +      ++ + DGHK FIN   F  +G  ++S D  G I  W               +W+ +  I E DL G+ IN L +HP G+RL +H++D  +R++DL+I A V K+ G  N    +    +PCGSF+F+GSED       YVWN++TGD VA+Y EL  S  + ++ +HP  +++AF   G    I +Y Y+
Sbjct:  277 DDSLVLGVYIHRTDKLKTDLMVSHPMVKVHVVDEVTGQYVKKEDSHRHVSSFYEQ-ENIEHILPIITQPFDFKKHKTTVPEWEEQIIFNERFGYFLQDDDESPRVMLLFEILDFISMEEARTNVSVDRHERGFRKIAWAFLKLVGTNGVLNIDTKLRLQLY-CPPPRAKKVPQTVEVFQWWSKYPRNKYTSTLYVTVKGLK--PPEHVDPGIRSMMALQQERGSTSY--SELNSEMTNKTSTQIQESKAETMKWSRMPGQVCRIPNKPMHSFRGGQMGCFTLCFSHDGRALAA-ACADRDAFPIIIYEIP--SGKVLSSFNGHLSVVYDLCWSRDDKGLLTASSDGTVRVWNVERLQTLAHK-------------------------TLPHPSFVYCAKFHPQAQSLVATGGYDGVLRVWNVDVQDVNGQLLQEFDGHKTFINTLCFDPEGSRMFSADNSGLIIVWGTKVMPGSRRGA-TSQWSIEREIKEADLNGISINSLEVHPNGRRLLIHAKDSVLRVMDLRILA-VKKYIGATNYRDRINSTFTPCGSFIFAGSED----GLAYVWNSETGDQVAVYSELCYSSALRAVAFHPHENMVAFCCFGQNQPIHLYLYD 856          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGE 3115
            VV+LY+Y+A RSDE+S  RG+++ ++++D  +W  G    G++GY PA+YVA E
Sbjct: 1030 VVSLYEYRANRSDELSMRRGDVVHVLYKDNDSWWFGRLVSGQEGYFPASYVADE 1083          

Query:  592 DDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNK-----HLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIH-NLAWCHK-----SELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            DD  VL + IHRTD+LKTDL V HPM++VH++D  TG+ + K++  R V+S  E  E +  ILP++TQPFDFK  + T+P WEE IIFNE   Y ++     P V+  FE+                                + +NG LN   K+RLQLY   P R K  P +  V  WW +  R  Y STLYVT+ G+K  P    +  +RSM   Q+E        S L     NK         +   +W R+P Q+C IPN P   F  G  G  TL FS DG  LA  A  + + FP++++++ +L      T   H  + H +  +C K       L+A+   DG  +VW +                     D   V G    +    H  F+  + F P   S + +A    +I +W                            G  +  G  +G    WS+ E E+K                E DL G+ IN L +HP G+RL +H++D  +R++DL+I A V K+ G  N    +    +PCGSF+F+GSED       YVWN++TGD VA+Y EL  S  + ++ +HP  +++AF   G    I +Y Y+
Sbjct:  277 DDSLVLGVYIHRTDKLKTDLMVSHPMVKVHVVDEVTGQYVKKEDSHRHVSSFYEQ-ENIEHILPIITQPFDFKKHKTTVPEWEEQIIFNERFGYFLQDDDESPRVMLLFEL--------------------------------VGTNGVLNIDTKLRLQLY-CPPPRAKKVPQTVEVFQWWSKYPRNKYTSTLYVTVKGLK--PPEHVDPGIRSMMALQQERGSTSY--SELNSEMTNKTSTQIQESKAETMKWSRMPGQVCRIPNKPMHSFRGGQMGCFTLCFSHDGRALAA-ACADRDAFPIIMWNVERL-----QTL-AHKTLPHPSFVYCAKFHPQAQSLVATGGYDGVLRVWNV---------------------DVQDVNGQLLQEFD-GHKTFINTLCFDP-EGSRMFSADNSGLIIVW----------------------------GTKVMPGSRRGATSQWSI-EREIK----------------EADLNGISINSLEVHPNGRRLLIHAKDSVLRVMDLRILA-VKKYIGATNYRDRINSTFTPCGSFIFAGSED----GLAYVWNSETGDQVAVYSELCYSSALRAVAFHPHENMVAFCCFGQNQPIHLYLYD 782          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGE 3115
            VV+LY+Y+A RSDE+S  RG+++ ++++D  +W  G    G++GY PA+YVA E
Sbjct:  928 VVSLYEYRANRSDELSMRRGDVVHVLYKDNDSWWFGRLVSGQEGYFPASYVADE 981          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPSGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NMVYIWNLQTKE--IVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1510 PTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWN 2274
            P   + GH   + +L+W  K+  L S+S D T ++W + +                              +  LC   H  FV A+AFHP  +   ++   D  +R+W+I   K  + +++DG    I  A F  +G+    G   G    +     +   +   +       V       G  I  +   P   ++ V S D  IRL DL+  ++ +K+ G VNS   ++   S   S++ SGSED      VY+W+
Sbjct:  333 PFCKYKGHTADLLDLSWS-KNYFLLSSSMDKTVRLWHISR------------------------------RECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTRLITAANFCQNGKYAVIGTYDGRCIFYDTERLKYHTQIHVRSTRGRNRV-------GRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDYSYIVSGSED----KYVYIWS 548          

Query:  565 KDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSN--VVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            K+  P  + D   VL + IHR+D+L T + V  P++++H+ID  TG  + K++    V+S  E  E    ILPV TQ +DFK  +  IP W+E II NE   Y ++     P VI FFE++D+  +   +     Q +  GF  +AWAFL+ + +N   N   K+RLQLY    + P  +  SSN  +  WW +  R  YPSTLYVT+ G+KL   +S  F +                   LP L   +      L +W RLP Q C IPN   +    G  G  ++ FS DG  LA  A  + + +P+ LY++   S       +GH  ++++L W    + L +AS+D T ++W++           +N+ ++ +              + L HP FVY   FHP  NS ++T  YD +IR+W++++ + +  ++ + DGH  FIN   F ++G  +YSGD+ G I  W     E K+     + W+   +I E  +KG+ +NHL +HP G+RL +HS+D ++R++DL+I A   K+ G  N  + LR   +PCG+F+F+GSED       YVWNA+TGD VA Y EL  + P+  + +HP  H++AF A G    + +Y Y+
Sbjct:   71 KEKHPKHLYDPSLVLGVYIHRSDKLLTRIMVSRPIVKIHVIDQRTGAYVKKESSINAVSSLKES-ESNAYILPVETQAYDFKRHKSPIPEWDEQIIINERFLYFLQENEDSPNVILFFEIIDICNSDGTNPNSESQIKEKGFRRLAWAFLKLVGANEVFNVDTKLRLQLY----YPPSRARLSSNCHIYEWWLKYPRNPYPSTLYVTVKGLKLKENVSFNFLL-------------------LPWLYSKE------LYKWSRLPGQACRIPNKRILSLRAGHMGCFSICFSNDGKTLA-AACADRDGYPIYLYEIP--SGECLGELHGHLNVVYDLCWSRNDQHLLTASSDATVRLWKI-----------ENEASSAL--------------KVLPHPSFVYTAKFHPKANSFVVTGCYDAVIRVWNVNVKESNGQLLQEFDGHNSFINTLCFDIEGLQMYSGDSSGLIIIWDTHISE-KSRLNPVQNWSIFKIIKEDYMKGIPVNHLQLHPNGRRLLIHSKDSTLRIMDLRILA-AKKYIGATNYREKLRSAFTPCGTFVFAGSED----RIAYVWNAETGDQVAKYSELSYTAPLRDVAFHPHEHMVAFCAFGQNQPVLVYIYD 632          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGE 3115
            VVALYDY A RSDE++  R ++I ++++D  NW  G   +G+QGY PANYVA E
Sbjct:  674 VVALYDYTAHRSDELTIHRSDIIHVLYKDNDNWWFGSLANGQQGYFPANYVASE 727          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP+G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D   K   +K +      KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS-KGKCLKTY---TCHKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--VVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP+G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D   K   +K +      KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS-KGKCLKTY---TCHKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--VVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP+G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D   K   +K +      KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS-KGKCLKTY---TCHKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--VVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP+G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D   K   +K +      KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYS-KGKCLKTY---TCHKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--VVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  V+ + IHRTDRLK+D  + HPM+++H++D  TG+ + K + +R V+S  E  + V  ILP+MTQP+DFK  +  +P WEE +IFNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P++      V  WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P           VD+  PGL      D     +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++   S        GH  II++L W      L ++S+DGT +VW          KN  N T+                 R L HP FVY   FHP    +++T  YD +IRIW I   +    ++ QLD HK F+N   F  +G  +YSGD  G I  W     ++ +       WT    I E + +GV I++L +HP GKRL +H++D ++R++DL+I A   KF G  N  + +   L+PCG+ LFSGSED      VYVWN +TG+ VA+Y +L     +  I YHP  +++AF A G    I +Y Y+
Sbjct:  185 PKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEK-DNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFEECPKVILFFEILDFLSMDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPRSQLNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEERGTPVYCERHRETSSVDTE-PGLE-----DSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEIP--SGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVW----------KNEINSTSTF---------------RVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDT-YVKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDLRILA-ARKFVGAANYREKIHSTLTPCGTLLFSGSED----GIVYVWNPETGEQVAMYSDLPFKSTIRDISYHPLENMVAFCAFGQSEPILLYIYD 769          

Query: 2642 ERKHTSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTS---GPEDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            E   + +I  +   L TVTEV R+  A            + N N   TS   GP  K R+    K+   L T  +         A  + +  P  +H +        VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++G+ PAN+VA E L  + P   +E     +P   TK
Sbjct:  820 ENSSSRKIQLVKQRLETVTEVIRSCAA------------KVNKNLSMTSPPPGPAKKPRV----KQSFVLTTDEIIHQFGLPQTAFISIERGPFVRHVDPPPM----VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKTK 984          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  V+ + IHRTDRLK+D  + HPM+++H++D  TG+ + K + +R V+S  E  + V  ILP+MTQP+DFK  +  +P WEE +IFNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P++      V  WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P           VD+  PGL      D     +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++   S        GH  II++L W      L ++S+DGT +VW          KN  N T+                 R L HP FVY   FHP    +++T  YD +IRIW I   +    ++ QLD HK F+N   F  +G  +YSGD  G I  W     ++ +       WT    I E + +GV I++L +HP GKRL +H++D ++R++DL+I A   KF G  N  + +   L+PCG+ LFSGSED      VYVWN +TG+ VA+Y +L     +  I YHP  +++AF A G    I +Y Y+
Sbjct:  185 PKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEK-DNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFEECPKVILFFEILDFLSMDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPRSQLNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEERGTPVYCERHRETSSVDTE-PGLE-----DSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEIP--SGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVW----------KNEINSTSTF---------------RVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDT-YVKVNDVQHSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDLRILA-ARKFVGAANYREKIHSTLTPCGTLLFSGSED----GIVYVWNPETGEQVAMYSDLPFKSTIRDISYHPLENMVAFCAFGQSEPILLYIYD 769          

Query: 2642 ERKHTSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTS---GPEDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            E   + +I  +   L TVTEV R+  A            + N N   TS   GP  K R+    K+   L T  +         A  + +  P  +H +        VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++G+ PAN+VA E L  + P   +E     +P   TK
Sbjct:  820 ENSSSRKIQLVKQRLETVTEVIRSCAA------------KVNKNLSMTSPPPGPAKKPRV----KQSFVLTTDEIIHQFGLPQTAFISIERGPFVRHVDPPPM----VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKTK 984          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCG-SFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYT 2412
            +++ FSP+G WLA  A +       L+        +   T  GH+  I ++AW   S  L SAS D T KVW M          R  +   T++                 H  FV+   F+P  N ++++  +D+ ++IW++   K   +  L  H   I+   F+ +G  + SG   G    W                 + Q +    D     ++ +   P GK +   + D +++L D      +  + G  N +  L    S  G  ++ SGSED    + VY+WN QT + V   +  G +  V S   HP  ++IA  A+ N+ +I++++
Sbjct:   43 SSVKFSPNGEWLASSAAD------ALIIIWGAYDGNCKKTLYGHSLEISDVAWSSDSSRLVSASDDKTLKVWDM----------RSGKCLKTLKG----------------HSDFVFCCDFNPPSN-LIVSGSFDESVKIWEVKTGK--CLKTLSAHSDPISAVNFNCNGSLIVSGSYDGLCRIWDAA--------------SGQCLRTLADEGNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCLFASFSVTGRKWVVSGSED----NMVYIWNLQTKEIVQRLQ--GHTDVVISAACHPTKNIIASAALENDKTIKVWS 325          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP+G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPNGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--IVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1519 TFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFE-LKNEAIFKEKWTSQSVIDE-LDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W     + LK   +F      +S +    D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   13 TISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSS----------GKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIVFVTSHEKRSPLRTPCDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--IVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 277          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVF-WWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFN----GHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  VL + IHRTDRLK+D  + HPM+++H++D  TG+ + K +  R V+S  E  E V  ILP+MTQP+DFK  +  +P WEE I+FNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P+ SP S    F WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P        +  VD+  PGL  +K      + +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++      P+  F     GH  II++L+W      + ++S+DGT ++W          KN  N  TNT               R L HP FVY   FHP V  +++T  YD +IRIW + + +    ++ Q D HK FIN   F  +G  +YSGD  G I  W+    ++ +       WT    I E + KG+ I++L +HP GKRL +H++D ++R++DL+I  +  KF G  N  + +   L+PCG+FLF+GSED      VYVWN +TG+ VA+Y +L    P+  I YHP  +++AF A G    I +Y Y+
Sbjct:  335 PKCLLDDDLVLGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSGRPVSSYYEK-ENVDYILPIMTQPYDFKQLKSRLPEWEEQIVFNENFPYLLRGSDESPKVILFFEILDFLSVDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPR-SPLSVVEAFEWWSKCPRNHYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEEKGKPVHCERHHESSSVDTE-PGLEESKE-----VIKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEI------PSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDGTARIW----------KNEIN-NTNTF--------------RVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNT-YVKINDLEHSVHHWTINKEIKETEFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRI-LVARKFVGAANYREKIHSTLTPCGTFLFAGSED----GIVYVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFCAFGQNEPILLYIYD 919          

Query: 2654 TSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTSGP---EDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            ++++  +   L TVTEV R+  A            + N N  +TS P     + +L +S+    T Q I      T T   +   KP     H+   +     VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++GY PAN+VA E L  E P   +E     SP   TK
Sbjct:  973 STKMQLVKQRLETVTEVIRSCAA------------KVNKNLSFTSPPAVSSQQSKLKQSNML--TAQEILHQFGFTQTGIISIERKP---CNHQ---VDTAPTVVALYDYTANRSDELTIHRGDIIRVFFKDNEDWWYGSIGKGQEGYFPANHVASETLYQELPPEIKERSPPLSPEEKTK 1133          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  V+ + IHRTDRLK+D  + HPM+++H++D  TG+ + K + +R V+S  E  + V  ILP+MTQP+DFK  +  +P WEE +IFNEN  YL++     P VI FFE+LD      I      Q +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P++ P    V  WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P           VD+  PGL      D     +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++   S        GH  II++L W      L ++S+DGT +VW          KN  N T+                 R L HP FVY   FHP    +++T  YD +IRIW +   +    ++ QLD HK F+N   F  +G  +YSGD  G I  W     ++ +       WT    I E + +GV +++L +HP GKRL +H++D ++R++DL+I A   KF G  N  + +   L+PCG+ LFSGSED      VYVWN +TG+ VA+Y EL     +  I YHP  +++AF A G    I +Y Y+
Sbjct:  186 PKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEK-DNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFDECPKVILFFEILDFLSMDEIKNNSEFQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPRSQPNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEERGTPVYCERHRETSSVDTE-PGLE-----DSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEIP--SGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVW----------KNEINSTSTF---------------RVLPHPSFVYTARFHPATRELVVTGCYDSMIRIWKVDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIAVWDT-YVKVTDVQHSVRHWTINKEIKETEFRGVPVSYLEVHPNGKRLLIHTKDSTLRIMDLRILA-ARKFVGAANYREKIHSTLTPCGTLLFSGSED----GIVYVWNPETGEQVAMYSELPFKSTIRDISYHPFENMVAFCAFGQSEPILLYIYD 770          

Query: 2642 ERKHTSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTS---GPEDKGRLMRSSKKGSTLQT--------IPMTLDMTSTSKANFT--FKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQ---------PVSPREDYEQNSPGTNTKTRFKDEYLE 3214
            E   + +I  +   L TVTEV R+  A            + N N   TS   GP  K R+    K+   L T        +P T    S  +  F     PPP              VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++G+ PAN+VA E L  +          P++P+E  +   P  + K+  KD +L+
Sbjct:  821 ENNSSRKIQLVKQRLETVTEVIRSCAA------------KVNKNLSITSPPPGPAKKPRV----KQSFVLTTDQIIHQFGVPQTA-FISIERRPFMRPVDPPPM-------------VVALYDYTASRSDELTIHRGDIIRVFFKDNEDWWYGSLGKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKAKMEKPPASRKSLIKDRFLD 1003          

Query:  577 PLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE-GAP--------NGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            P  + DD  V+ + IHRTDRLK+D  + HPM+++H++D  TG+ + K + +R V+S  E  + V  ILP+MTQP+DFK  +  +P WEE +IFNEN  YL++     P VI FFE+LD      I     VQ +  GF  IAWAFL+ + +NG+ N   K+RLQLY   P +P++      V  WW +  R  YPSTLYVT+ G+K+   I   +  RSM   Q+E G P           VD+  PGL      D     +W RLP Q C IPN        G  G   L FS +G  LA  A  + + +P++LY++   S        GH  II++L W      L ++S+DGT +VW          KN  N T+                 R L HP FVY   FHP    +++T  YD +IRIW I   +    ++ QLD HK F+N   F  +G  +YSGD  G I  W     ++ +       WT    I E + +GV I++L +HP GKRL +H++D ++R++DL+I A   KF G  N  + +   L+PCG+ LFSGSED      VYVWN +TG+ VA+Y +L     +  I YHP  +++AF A G    I +Y Y+
Sbjct:  185 PKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEK-DNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFEECPKVILFFEILDFLSMDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLY-YPPTKPRSQLNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSY--RSMMALQEERGTPVYCERHRETSSVDTE-PGLE-----DSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILA-AACASRDGYPIILYEIP--SGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVW----------KNEINSTSTF---------------RVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDT-YVKVNDVQTSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDLRILA-ARKFVGAANYREKIHSTLTPCGTLLFSGSED----GIVYVWNPETGEQVAMYSDLPFKSTIRDISYHPLENMVAFCAFGQSEPILLYIYD 769          

Query: 2642 ERKHTSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTS---GPEDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTK 3187
            E   + +I  +   L TVTEV R+  A            + N N   TS   GP  K R+    K+   L T  +         A  + +  P  +H +        VVALYDY A RSDE++  RG++I++ F+D ++W  G    G++G+ PAN+VA E L  + P   +E     +P   TK
Sbjct:  820 ENSSSRKIQLVKQRLETVTEVIRSCAA------------KVNKNLSMTSPPPGPAKKPRV----KQSFVLTTDEIIHQFGLPQTAFISIERGPFVRHVDPPPM----VVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKTK 984          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            +++ FSPDG WLA  + +         YD          T  GH   I ++AW   S+L+ SAS D T K+W ++            +   T++                 H  +V+ V+F+P  N ++++  +D+ +RIWD  +N  +    +  H   +    F+ DG  + SG   G +  W     +L N    ++              G  ++ +   P GK +   + D ++RL         +K +      KN + C+       CG ++ +GSED    + +Y++N QT + V      G    V ++  HP  ++IA  A+  + S++I+
Sbjct:   50 SSVKFSPDGKWLASASADKTIKIWGA-YD-----GKFERTLEGHKEGISDIAWSQDSKLICSASDDKTIKIWDVE----------SGKMVKTLKG----------------HKEYVFGVSFNPQSN-LIVSGSFDENVRIWD--VNTGECTKMISAHSDPVTGVHFNRDGTLVVSGSYDGTVRIWDTTTGQLLNTISTED--------------GKEVSFVKFSPNGKFVLAGTLDNTLRLWSYNNNKKCLKTY---TGHKNEKYCIFSTFSVTCGKWIVTGSED----NLIYIYNLQTREIVQTLA--GHEDVVLTVACHPTENIIASGALEKDRSVKIW 332          

Query: 1393 DGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            +  +++ FSP+G WLA  + + +    ++++      +    T  GHN  I ++AW   S  L SAS D T K+W M          R  +   T++                 H  +V+   F+P  N ++I+  +D+ ++IW++   K   +  L  H   ++   F+  G  + SG   G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  +LIA  A+ N+ +I+++  N
Sbjct:   42 EAVSSVKFSPNGEWLASSSADRL----IIIWGAYDGKYE--RTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDM----------RSGKCLKTLKG----------------HSNYVFCCNFNPPSN-LIISGSFDETVKIWEVKTGK--CLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAA--------------SGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NLVYIWNLQTKE--IVQKLQGHTDVVISAACHPTENLIASAALENDKTIKLWMSN 329          

Query:  586 IEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNE-DIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH-PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKH------------------------------LDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIW--DISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNSE 2424
            IEDDGRVL I +HRTD+LKTD  + HP++R+HI+D +TG  + KQ++DR VT   E  ++ +  ILPV+TQP+DFK ++ T+P WEE +IFNEN NY ++  P V+ FFE+LD     +  + + V ++  G+H +AWAFL+ + SNG  NT  K+RLQL++  P + K  P   +V  WW +  R  YPSTLYVT+ GI+       E A RSMF  QK         +H+  L LNKH                               D    S W RL  Q C +PN  ++   TG  G   L FSPDG  LACG   + + +P+L+Y++   S      F GH  II++L W   S+ L SAS+D T ++W ++K                         GS  +K  L HP FVY   FHP V ++++T GYDK+IRIW  D+  +  +++ +L+G KGFIN   F  DG+ ++SGD+ G +  W+V   E+ +       W+    I++ + +G  IN++ MHP G+RL VH RD +IR+IDL+I A++ ++ G +N  + +R  +S CG+F+ SGSED  +    YVWNA+TGD VA+Y EL    PV+ +D+HP  +++AF + G  + + IY Y+ +
Sbjct:  233 IEDDGRVLGITVHRTDKLKTDFFIAHPLVRIHIVDAATGSHVKKQHRDRAVTWYYERKVDGLDYILPVLTQPYDFKKQKSTLPMWEELVIFNENYNYFLQQDPKVMIFFEILDFISMNAARQKYNVAKQEGGWHRVAWAFLKVLGSNGHFNTDKKLRLQLFQP-PFKFKAKPGVVDVYQWWLELPRVHYPSTLYVTVKGIRPPNPDEIEPAGRSMFATQK--VCRVCFSAHV--LVLNKHNRYLKDSLLIFCQIFSYHYSQSILSSVCRDEDKKTPSTWSRLAGQACKVPNNLNLTLPTGRQGCFVLKFSPDGRKLACGC-HDKSTYPILVYEIP--SGQLKGQFLGHYSIIYDLCWTKDSKSLLSASSDATARIWNIQKF------------------------GSLSEK-LLPHPAFVYTAQFHPRVPTVVVTGGYDKLIRIWNTDMQGHHAELVQELEGQKGFINTICFDEDGQKMFSGDSIGTLRVWNVYVTEMPSRKGVLRDWSLYKEINDEEYEGTPINYVTMHPGGRRLLVHCRDNTIRMIDLRIFAVMQRYIGALNFREQIRSTISQCGTFVVSGSEDYGA----YVWNAETGDQVAMYTELNYKKPVTCVDFHPHDNMVAFASFGENNPVLIYIYDHQ 842          

Query: 2870 TSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVA 3109
             +  K  F+F+PPP +K+K    K   +V ALYDYQAQRSDE+S  RG+++ ++++D +NW +GE  DG+QG+ P+NYVA
Sbjct: 1032 ATQGKPQFSFQPPPTTKNKTAVQK---QVKALYDYQAQRSDELSLVRGDIVTVLYKDSENWWMGELLDGQQGFFPSNYVA 1108          

Query:  592 DDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQ-VTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH-PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKHLDVSA--LSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKK-DIIHQ-LDGHKGFINCALFSLD-GRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNSE 2424
            D+G+VL++MIHRTD+LK D  +LHP++RVH+I+  TG+ I KQ++DR VT  +E   Q V TILP+MTQPFDFK R+ TIP WE+ ++FNEN NY  +H P VI  FE+LD     +  + F  Q+   G+H IAWAFL+ +  N  +N G+K+RLQL+   P++         V  WW+   R  YPSTLYVT+  I+   E+S   AMRSMF  QKE       D      +  +    S   LS W RL  Q+C +PNV  +    G  G   L FS DG  LAC A ++ ++FP+L+Y++ K +      F GH  II++L W     LL SAS+DGT ++W ++K+                           G  R L HP +VY   FHP V SI++T GYD+++R+WDIS+ +  +++ Q ++ H G IN   F  D G+ +YS D+ G I  W+V   E  +   F   WT    + E DLK   IN++ MHP+G+RL VH R+ +I + DL+++ ++ K+ G  N ++ +   ++PCGSF+FSGSED     +VY WN  TGD VA+Y +L    PV+ + YHP+ H++A  ++G    I IY Y+ +
Sbjct:  281 DEGQVLALMIHRTDKLKNDFYILHPVVRVHVINEETGEYIPKQHQDRAVTFYSETNNQSVKTILPMMTQPFDFKERKSTIPVWEDLLVFNENFNYFTQHNPKVILLFELLDFVSMNTASRQFVTQKREGGWHRIAWAFLKVLGKNDKVNVGNKLRLQLF-VPPNKTAKVSSQPEVYQWWKFGQRVPYPSTLYVTLKSIETPQEVSP--AMRSMFATQKELGSMKYEDLKSRNWSSQEKTLTSGRTLSTWTRLLGQLCRVPNVLSMTLPAGKKGCFVLKFSNDGRNLAC-ACQDGSDFPILIYEIPKGTLK--GQFQGHFAIIYSLCWNKSDTLLMSASSDGTVRIWDIQKLGE-------------------------GHIRLLPHPGYVYTAEFHPRVESIVVTGGYDEVVRVWDISLPEDYNVLQQEMEEHHGHINSICFDTDDGQKMYSADSVGTILIWNVYVTEQASRKHFVRDWTKYLELKEPDLKETPINYIKMHPSGRRLLVHGRNNAIYMFDLRVQRVMQKYFGAENLKEKICSTITPCGSFVFSGSED----GKVYAWNTDTGDQVAVYTQLNYIMPVTDVHYHPRDHMLAICSLGENQPIYIYKYDPQ 863          

Query: 2870 TSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEEL 3121
            TS  K  FTF+ P  +         + +V+A+YDY+AQRSDE++  +G++I ++++D + W +GE  DG+QG+ PANYV  ++L
Sbjct: 1043 TSLGKPQFTFEAPVKTSR-------VNKVIAIYDYRAQRSDELNLYKGDIITVLYKDNEKWWMGELPDGQQGFFPANYVTEDDL 1119          

Query:  541 KTDSQEIEKDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDI-EQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK-HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYEN-GPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVD-SHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKI-TSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINK--KDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            +T+   +E++     IED+G++L++ +HRTD+LK D ++LHPM+RVHI++  TG  + KQ KDR V++  E   + VT I+P+MTQPFDFK R+  +P WEE ++FNEN NY  + +P VI FFE+LD     +  + +   +   G+H IAW FL+    N  LN G KVRLQL+E     RPK  P    +  WW+ + R+ YPSTLYVT+ GI  +P  + E AMRSMF  Q+E       D       +  +  D   LS W RL  QMC IPN   +    G  G   + FS DG  LAC A  +  N+P+L+Y++   S      F GH  I+++L+W  K + + SAS+DGT +VW ++   TSEK                            L HP FVY   FHP V++I+ T GYD+++RIWD+ ++     +  +++ H+G +N   F  DG+ +Y+ D+ G +  W+V   E  ++  F   W     + + ++K V IN++ +H +G+RL VH RD  IR++DL+I+ ++ K+ G +N  + +R  ++PCGSF+FSGSED    +  Y WN  TGD VA+Y EL    PV+ IDYHP+ H+ A  ++G+   I +Y Y+
Sbjct:  359 ETEEHRLEREA----IEDEGQILAVTVHRTDKLKNDFHILHPMVRVHIVNEETGLNLTKQKKDRAVSTYFETQNDNVTQIVPIMTQPFDFKERKSVLPVWEELLVFNENFNYFTQDYPKVIVFFELLDFVSMSTASRQYEDSKSEGGWHRIAWGFLKVKGMNDKLNVGSKVRLQLFEPVYKFRPK--PDQVELWQWWKTQGRRPYPSTLYVTMKGI--TPPDTVEPAMRSMFATQREVGSRTYADLKKSINWSDARDTDRKTLSSWSRLVGQMCRIPNQMKLTLPAGRKGCYVVKFSHDGRNLAC-ACHDRENYPILVYEIP--SGQLLGKFRGHFGIVYDLSWSKKDDYICSASSDGTVRVWSLENFNTSEK---------------------------LLPHPGFVYTAQFHPRVDNIIATGGYDQVVRIWDVDVDSVHGQLKQEIENHRGHVNSLCFDDDGQKMYTADSVGIVLIWNVYVTEKVSQKGFLRDWIKYQELTDPEMKDVPINYIQLHHSGRRLLVHCRDNIIRMVDLRIQRVMQKYIGALNFREQIRSSITPCGSFVFSGSED----NYAYAWNTDTGDQVAMYSELNYRHPVTDIDYHPRDHMYAACSLGDNQPIVVYDYD 949          

Query: 2882 KANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEE 3118
            KA F+F+ P       +++   G V ALYDY+AQRSDE++  + ++I ++++D ++W +GE  DG+QG+ PANYV  E+
Sbjct: 1129 KAQFSFQAPAG-----KAVPGYGVVKALYDYRAQRSDELTIFKNDVITVLYKDNESWWMGELPDGQQGFFPANYVLAED 1202          

Query:  547 DSQEIEKDTDPLL-IEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNE-DIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKHPA-VIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVD-SHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDII--HQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            D  E+++  + ++ +ED+G VLS+ +HRTD+LK D ++LHP++RVHI+D +TG  + KQ+ DR VT+  E + E V  ILP+MTQPFDFK R+  +P WEE ++FNEN NY ++    VI FFEVLD     +  + F  Q+   G++ IAWAFL+   +N  LNTG KVRLQL+   P      P    V  WW    R+ YPSTLYVTI GI+   ++     MRSMF  Q+E       D          K  +   LS W RLP Q C IPNV  +    G  G   L FS DG  LAC A  + + +P+ +Y++   S        GH  ++++L W  +   L SAS+DGT +VW +    S                           ++ L HP FVY   FHP ++S++ T GYD++IR+WD+S ++   +   +++ H+G +N  +F  DG  +YSGD+ GN+  ++V   E +    ++  WT    I + +LK V IN L +H  G+RL VHSRD  IR+ DL+++ ++ K+ G +N  + +   L+PCGSF+FSGSED    +  Y WN +TGD VA++ EL    PV+ + YHP+ H++A  A+G+   I IY Y+
Sbjct:  267 DEAELQRRREEMMKVEDEGEVLSVTVHRTDKLKNDFHILHPLVRVHIVDETTGNYLHKQHMDRAVTAFFETENEHVDKILPIMTQPFDFKERKSVLPVWEELLLFNENFNYFIQSDVKVIVFFEVLDFVSMNTARRQFSNQKREGGWYRIAWAFLKVRGNNDKLNTGSKVRLQLFVP-PSGFSAKPNQLEVYQWWSSMKREPYPSTLYVTIKGIRPPRDVEPAL-MRSMFATQEEVGSRTYTDLKKSTQWGEKKKGEHKTLSSWSRLPGQTCRIPNVLQVTLPAGKKGCFVLRFSHDGRSLAC-ACNDRDQYPIYIYEVP--SFELRGKLKGHFGLVYDLCWSKRDTHLLSASSDGTARVWNLDNFDS--------------------------SEKLLPHPGFVYTAKFHPRLDSVIATGGYDQVIRVWDVSGSEPHGVLKQEIEDHRGHVNTLVFEEDGGKMYSGDSAGNVIIFNVFVGEQEPRLGWERDWTLFKKILDPELKDVPINCLTLHHNGRRLLVHSRDNIIRMFDLRVQRVMQKYIGALNFREEIHSTLTPCGSFVFSGSED----NFAYTWNTETGDQVAMFSELNYQFPVTDVAYHPRDHMMALCALGDNQPILIYNYD 861          

Query: 2855 MTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEE 3118
            ++L    + KA F+F+ P     K  S K   +V+A+YDY+AQRSDE++  +G++I ++++D  NW +GE  DG+QG+ P++YVA E+
Sbjct: 1038 ISLSQQESGKAQFSFQAPAG---KSVSRK---QVIAMYDYRAQRSDELTIFKGDVITVLYKDNDNWWMGELPDGQQGFFPSSYVAEED 1119          

Query:  556 EIEKDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMK----HPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKE------GAPNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISIN--KKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            E+E    P  + DD  VL + +HRTD+LKTDL V HPM++VH+ID  TGK + K++  R V+S  E  E+V  +LP+MTQP+DFK  + TIP WEE IIFNE   Y ++     P VI FFEVLD            V +   GF  IAWAFL+ + +NG LN   K+RLQLY   P R K   +S  VV WW++  R  Y STLYVTI G+KL   +    ++RSM   Q+E      G P+  V        L    D+    +W R+P Q+C IPN P + F  G  G   L FS  G  LA  A  + + FPV++Y++   S      FNGH  I++++ W    + L SAS+DGT ++W M+++                             K+ L HP FVY+  FHP   ++++T GYD +IR+WD+++      ++H+ +GHK FIN   F  +G  L+S D+ G +  W++P  +   +   +  W  +  I E DLKG+ IN L +HP G+RL +H+RD  +R++DL+I A V K+ G  N  + +R   SPCGSF+FSGSED       YVWNA+TGD VA+Y EL    P+  + +HP  +++AF A G    + +Y Y+
Sbjct:  303 EVENKEPPKPVFDDSLVLGVYVHRTDQLKTDLLVSHPMVKVHVIDEVTGKYVKKEDSHRPVSSFYEQ-EKVEHVLPIMTQPYDFKKNKSTIPEWEEQIIFNERFGYFLQDDNESPRVILFFEVLDFVSMDEARANVVVDEHERGFRKIAWAFLKLVGTNGVLNVDSKLRLQLY-CPPPRVKKQSHSVEVVEWWRRYPRSRYASTLYVTIKGLKLPEHVDP--SVRSMTALQQERGTTLFGDPHNDVAQKSSTQLLEDQADI---VKWGRVPGQVCRIPNKPMLSFRGGQMGCLVLRFSHAGRRLAA-ACADRDAFPVVVYEIP--SGKVLAAFNGHLSIVYDVCWSRDDQSLLSASSDGTVRIWNMERLRGVA-------------------------KKILPHPSFVYSAQFHPVGQNLVVTGGYDCLIRVWDLNVQDVNGQLLHEFEGHKTFINALCFEAEGLRLFSADSAGLLIVWNMPVGDGSYQHPTR-LWNIEREIMESDLKGIAINGLEVHPNGRRLLIHARDSVLRVMDLRILA-VKKYTGATNYRERIRSTFSPCGSFVFSGSED----GMAYVWNAETGDQVAVYSELCYPTPLRDVAFHPHENMVAFCAFGESQPVHVYIYD 894          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYV 3106
            VV LYDY A RSDE++  RG++I+++++D +NW  G   DG+QGY PANY 
Sbjct: 1077 VVFLYDYTANRSDELTVCRGDVIQVLYKDNENWWFGCLADGRQGYFPANYA 1127          

Query:  562 EKDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSH--LPGLALNKHLDVSA-LSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTC---KVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISIN--KKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            E +  P  + D+  VL + IHRTDRLKTDL V HPM++VH++D  TG+ I K++  R+V+S  E  E +  ILP++TQPFDFK  + T+P WEE IIFNE   Y ++     P VI FFE+                                + +NG LN   K+RLQLY + P R K  P +  V  WW +  R  Y STLYVT+ G+KL   +     +RSM   Q+E       + H  L      + L+  A +  W RLP Q+C IPN               L  S  G  + C                                    L + H    LA+A AD       VW ++++ +   K                          L HP FVY   +HP   ++L+T GYD ++R+W++ +      ++ + +GHK FIN   F  +G  +YSGD  G I  W+  + E ++       W  +  I E DL G+ IN L +HP G+RL +H++D  +R++DL+I A V K+ G  N    +    +PCGSF+FSGSED       YVWNA+TGD VA+Y EL     +  + +HP  H++AF A G    I IY Y+
Sbjct:   66 EVEDSPRQVFDENLVLGVYIHRTDRLKTDLLVSHPMVKVHVVDEITGQYIKKEDSHRRVSSFYEQ-ENIDHILPIITQPFDFKKNKSTVPEWEEQIIFNERFGYFLQDSEECPQVILFFEL--------------------------------VGTNGVLNIDSKLRLQLY-SPPTRAKKVPQTVEVFQWWSKFPRNRYASTLYVTVKGLKLPEHVDP--GIRSMMALQQERGSTSYSELHTDLAQKTSTQLLEGKAEVITWSRLPGQVCRIPN--------------KLMLSFRGGQMGCFI----------------------------------LRFSHDGRALAAACADRDAFPIVVWNIERLQALAQK-------------------------VLPHPSFVYCAQYHPLNQNLLVTGGYDCLLRVWNLDVKDVNGQLLQEFEGHKTFINALCFDNEGTRMYSGDNAGVIVVWNT-KTEDRSRHGPTHLWKIEKEIKESDLNGIPINSLEVHPNGRRLLIHAKDSVLRVMDLRILA-VKKYIGATNYRDRINSAFTPCGSFIFSGSED----GLAYVWNAETGDQVAVYSELCYPVSLRGVVFHPHEHMVAFCAFGQSQPIHIYMYD 581          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEE 3118
            VV+LYDY A RSDE++  RG++I ++++D ++W  G   +G++GY PA YVA E+
Sbjct:  726 VVSLYDYSANRSDELTVRRGDVIHVLYKDNESWWFGCLANGQKGYFPAAYVADEK 780          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPSGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NMVYIWNLQTKE--IVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTL-CHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            +++ FSP+G WLA  + +       L+            + +GH   I ++AW   S LL SAS D T K+W M                           GS    +TL  H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W              +  + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED      VY+WN QT +   + K  G +  V +   HP  ++IA  A+ N+ +I+++
Sbjct:   46 SSVKFSPNGEWLASSSADK------LIKIWGSFDGKFEKSLSGHKLGISDVAWSPDSNLLVSASDDKTLKIWDM---------------------------GSGKCLKTLKGHSNYVFCCNFNPQSN-LVVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRMW--------------DSTSGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCVFANFSVTGGKWIVSGSED----HMVYIWNLQTKE--IVQKLQGHADVVIATACHPSENIIASAALENDKTIKLW 327          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S          S P+  L N       W         D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPSGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------SSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVS----------SSPQLLLFN-------W---------DDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NMVYIWNLQTKE--IVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 318          

Query: 1522 FNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWN 2274
            +  H   + +L+W  K+  L S+S D T ++W + +                              +  LC   H  FV A+AFHP  +   ++   D  +R+W+I   K  + +++DG    I  A F  +G+    G   G    +     +   +   +       V       G  I  +   P   ++ V S D  IRL DL+  ++ +K+ G VNS   ++   S   SF+ SGSED      VY+W+
Sbjct:  602 YKSHTADLLDLSWS-KNYFLLSSSMDKTVRLWHISR------------------------------RECLCCFQHVDFVTAIAFHPRDDRYFLSGSLDGRLRLWNIPDKKVALWNEVDGQTRLITAANFCQNGKYAVIGTYDGRCIFYDTERLKYHTQIHVRSTRGRNRV-------GRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDYSFIVSGSED----RYVYIWS 813          

Query:  511 RRPKQDKIETKTDSQEIEK--DTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNE----DIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNEN-SNYLMKHPAVI---YFFEVLDLNPAYSIDKT----FPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEIS-SEFAMRSMFPNQKEGAPN--GLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHP-FVNSILITAGYDKIIRIWDI--SINKKD--IIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            RRPK  K   K +++  E+  + +    E+D + L +++HRTDRL +D  +   ++RV+++D +TG+ + K++ ++   + ++    D E      P+ TQP D +  R  +P WEE ++FN     +L   P V+     FEV+DL    S+D+T      ++ +S G   +AWAFL+ + +NG +N G K+RLQL+   P R + +     V  W+ +  R  YP+T+YVT+ G++L  ++  S  +M ++   Q   AP+  G   +  P  A  +     AL +W RLP Q C+IPN   +    G  G   + FSPDG  LA  A  + ++ PV ++++   S        GH  ++++L+W H S  L SAS+DGT ++W ++      +K                          L HPCF YA   HP    ++ +T  YD ++R WD+  ++  +D  ++ +LDGH+G++N   F  DG  ++SGD+ G +  W     +  N    ++ W     I E DLKGV INHL  HP G+RL VH+RD ++RLID++++ +  KF G  N  + +  C+SPCG+FL SGSED       YVWN  TGD VA+Y ELG   PV  + +HP  H++AF   G+   + ++ Y+
Sbjct:   33 RRPKAAKRTKKKNAKGEEQYLEQEAERREEDEQALGVVVHRTDRLASDPLLACALVRVYVVDAATGQHVHKEDSEQPAAAPSQPGSSDSEH-----PLTTQPCDVRAHRSLLPEWEEQVVFNHRLGPFLRVEPGVVRVLLLFEVVDL---VSMDETQTNYSALETDSGGRRCLAWAFLKLVGANGAVNVGGKMRLQLFYP-PARFRPTAGVLPVYEWYAKHARLRYPATIYVTVKGLRLPSQLDPSGRSMMTLQQEQGSRAPDEQGSGAASSPVRASQRR---DAL-KWSRLPGQTCYIPNKLALTLKVGTAGCFRVRFSPDGRALAA-ACAHRDSHPVFVFEVP--SGQLLMELPGHLGLVYDLSWSHDSSHLLSASSDGTARLWNVEGRVRAAEK-------------------------VLPHPCFTYAGQLHPGATAAVAVTGAYDGVLRAWDVGGAMGTRDGRLLRELDGHRGYVNAVCFDADGLQMFSGDSTGVVLVWRTFVSQTANSNPVRD-WAVTKEIKEPDLKGVPINHLWAHPNGRRLLVHARDSALRLIDIRVQ-VTRKFTGASNQRERVHSCISPCGTFLLSGSED----GVAYVWNVDTGDQVAMYSELGYQAPVRDVHFHPHEHMVAFCCHGDAQPVLVFAYD 643          

Query: 1393 DGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTN---TIEADTVPVGGSFGDKR----TLCHPCFVYAVAFHP-FVNS--------ILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVW 2271
            D   ++ F+P+   LA G+++      +++++    +      F GH   + ++ +     L+ SAS D T ++W +  +  E    + +  T    +  AD   +  +  DK     T+    F+Y++  H  +V S        ++++   D+ +R+WD   N ++ +H    H GF+N   F   G  + +      +  W +   +L               +    + G  +N L  HPTG  L   S D +++++DL    +    HG  +         S  G F  SG  D     QV VW
Sbjct:   19 DTITSVDFNPNMKQLASGSMDAC----LMVWNFKPQTR--AYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLW-VPSVKGESTVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDS--NSRECVHTFYEHGGFVNQVDFHPSGTCIAAAGTDNTVKVWDIRMNKL---------------LQHYQVHGAAVNSLSFHPTGNYLITASNDSTLKVLDLVEGRLFYTLHG--HQGPATAVAFSRAGDFFASGGSD----EQVMVW 297          

Query: 1342 QMCHIPNVPHIKFFTG-ADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSED 2241
            +M  IPN   I    G  D      F+P G  LA G      +  V ++D ++ +     T  GH   +   +W    + +AS+S D + KVW    + SE    R  QT                      H   V +V F P+ +S L+T+  DK + +WD    +   I    GH    N   F+L G T+ S D+ G I  W V     K  A              L+L     N L  HP+G  + V S D  +R++DL +   V    G  ++ + +    SP G  LFSG  D
Sbjct:  360 KMWSIPNGDIIMTGQGHTDWIGDCDFNPTGTNLATGG----GDSTVKVWDFSQGA--CVLTLEGHGHAVWGCSWHSCGDFIASSSMDNSSKVW---DVNSE----RCRQTLRG-------------------HTDSVNSVEFLPY-SSTLLTSSADKTLSLWDARTGRCAQI--FYGHLHSCNHGTFNLKGDTVVSCDSYGVIKVWDVR----KGTATMT-----------LNLGPHPANRLSFHPSGHVMAVASDDACVRIVDL-LTGHVETLSGHEDAVQAV--VFSPDGDTLFSGGSD 607          

Query: 1372 IKFFTGADGANTLAFSPDG------AWLACG---AIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEK----DKNRDNQTTNTIEADTVPVGGSFG-----DKR------TL-CHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCW 1956
            +K +  + GA  L     G      +W +CG   A  +M+N   + +D+   S     T  GH   ++++ +   S  L ++SAD T  +W  +     +      +  N  T  ++ DTV    S+G     D R      TL   P     ++FHP    ++  A  D  +RI D+       +  L GH+  +   +FS DG TL+SG + G I  W
Sbjct:  401 VKVWDFSQGACVLTLEGHGHAVWGCSWHSCGDFIASSSMDNSSKV-WDVN--SERCRQTLRGHTDSVNSVEFLPYSSTLLTSSADKTLSLWDARTGRCAQIFYGHLHSCNHGTFNLKGDTVVSCDSYGVIKVWDVRKGTATMTLNLGPHPANRLSFHP-SGHVMAVASDDACVRIVDLLTGH---VETLSGHEDAVQAVVFSPDGDTLFSGGSDGTIRMW 613          

Query: 1735 HPCFVYAVAFHPFVNSILITAGYDKIIRIWDI-SINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEK-NLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIA 2370
            H   V A+   P V+   I+A  DK IR+WD+ S N + ++H     +G   C+ F  +G    +G     +  + +  F+    A F+ +          D  G+ I++      GK + + +  G +RL+D    + +  F G  NS+   L    SP   F+ +GSED     +++VW+ ++G  VAI  +   +GPV+ + ++PK  ++A
Sbjct:  106 HTKKVVALCMSP-VDDTFISASLDKTIRLWDLRSPNCQGLMHL----QGRPVCS-FDPEGLIFAAGLNSEMVKLYDLRSFDKGPFATFRLQQDRTC-----DWTGLKISN-----DGKFILIATNGGVLRLVDAFQGSALHMFTGHTNSKGITLEASFSPDSQFIMTGSED----GKIHVWHTESGTKVAIL-DGKHTGPVTCLQFNPKYMMVA 298          

Query: 1684 ADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEF-ELKNEAIFKEKWTSQSVIDELDLKGVIINHLIM-----------------------HPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRC-CLSPCGSFLFSGSED 2241
             ++VP    F  K+   H   V+ VA  P  N++ +T G D +  +W   +   +I+    GHK  + C  FS D   + +GD  G I  WS+    EL +  +   +W        + L G     + M                        P GK   V   DG++R+ DLK    V  F G    + ++ C  +   G+ + +GS D
Sbjct:   48 GESVPDDSEFTVKK---HKGAVFCVALDPKSNALAVTGGEDDLAYVW--RVGDGEILFPCTGHKDSVTCTGFSHDSSMVATGDMSGLIKVWSLATAQELWSFEVSDLEWIEWHHKAPVLLAGTNSGEVWMWKIPAGDCRTFQGPGCQSMCGKIFPDGKVAVVGYEDGTVRIWDLKQSTPVFTFKGKDGHQGSVTCVAVHDDGTLVLTGSVD 253          

Query: 1735 HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFK-EKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWN 2274
            H   +   AF P  +S ++T   D   RIWD   + +  +H L GH  ++ C  +S DG  + +G     I  W     +   +A+    KW     I  L  + +   HL+   +  RL   S+DG+I++ D   +       G  NS   + C        L+SGS D      V VW+
Sbjct:  142 HGSTILCSAFAPHTSSRMVTGAGDNTARIWDC--DTQTPMHTLKGHYNWVLCVSWSPDGEVIATGSMDNTIRLWDPKSGQCLGDALRGHSKW-----ITSLSWEPI---HLVKPGSKPRLASSSKDGTIKIWDTVSRVCQYTMSGHTNS---VSCVKWGGQGLLYSGSHD----RTVRVWD 305          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSL----DGRTLYSGDAKGNIHCWSVP 1965
            N L  + D   LA    +N     V LYD+   + +P  +F GH   + ++++   +  + ++S DGT KVW ++                   + ++P        R   H   V  V  HP     LI+   D  IRIWD+  N+    HQL       + +L SL    DG  L + + KGN + W +P
Sbjct:   36 NRLEITNDKKLLATAGHQN-----VRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVR-------------------SPSIP--------RNYKHNAPVNEVVIHPNQGE-LISCDRDGNIRIWDLGENQ--CTHQLTPED---DTSLQSLSMASDGSMLAAANTKGNCYVWEMP 189          

Query: 1405 TLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLD-------GHKGFINCALFSLDGRTLYSGDAKGNIHCWSV 1962
            ++ FSPDG +LA GA + +    + ++D+   +        GH + I++L +    + L S S D T ++W +          R  Q + T+  +                   V  VA  P     +     D+ +R+WD       ++ +LD       GHK  +   +F+ DG+++ SG    ++  W++
Sbjct:  448 SVCFSPDGKFLATGAEDRL----IRIWDIE--NRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDL----------RTGQCSLTLSIED-----------------GVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGF--LVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNL 605          

Query: 1408 LAFSPDGAWLACGAIENMNNFPVLLYDLTKLSH--HPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGD-KRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIK--------AMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYK 2307
            L FSP G +LA G      N  +++YD+        P N    H R I ++AW     LL ++S D + K+W         D ++ ++    I  D+   G  + D KR LC      A  F    ++ +I    D +  +   S  K+  +     H   + C + +     +  G +KG +  +       + E I   K TS +           I HLI+   G+RL ++  D +IR  ++ I          +  K+  ++N  +      S   +     S   SS  ++Y+W   +G  V + +
Sbjct:   32 LQFSPCGDYLALGCA----NGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDGRLLLTSSRDWSIKLW---------DLSKPSKPLKEIRFDSPIWGCQWLDAKRRLC-----VATIFEE-SDAYVIDFSNDPVASLLSKSDEKQ--LSSTPDHGYVLVCTVHTKHPNIIIVGTSKGWLDFYKFHSL-YQTECIHSLKITSSN-----------IKHLIVSQNGERLAINCSDRTIRQYEISIDDENSAVELTLEHKYQDVINKLQWNCILFSNNTAEYLVASTHGSSAHELYIWETTSGTLVRVLE 309          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFR--DGKNWLLGETCDGKQGYLPANYV 3106
            V ALYDYQAQ + ++SF  G +I+IV R  D   W  G   +G+QG  P NYV
Sbjct:  426 VTALYDYQAQAAGDLSFPAGAVIEIVQRTPDVNEWWTGR-YNGQQGVFPGNYV 477          

Query:  766 VTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLM----KHPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENG--PHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIW--DISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNSERNC 2433
            V  ILPVMTQPFDFK  +  +P WEE ++FNE  +Y +      P V+  FEV   N A +  K     +   G++H+AWAFL+ + +NG +NT  KVRLQL+  G    R ++ P    V  WW+   R  YPSTLYVT+ GI    E+                          PGL   K  + +  + W RLP Q+  IPN   +   +G  G   + FS +G +LAC A  +M++FPV++Y++   S   +    GH  II++L W    + L SAS+DGT ++W  K + +   K                          L HPCFVYA  +HP    I++T GYD+++R+W  D       ++ +L GH GF+N   F   G T++S D+ G I  W   +  L    I   K   ++  DEL  KG +IN +++HP  ++L VH+R+ ++ ++DL+   ++ ++ G  N ++++   +S CGSF+FSGSED       YVWN  TGD V+IY  L     VS +D+HP  HLI F + GN   + +Y YN +  C
Sbjct:    2 VDYILPVMTQPFDFKKNKCLVPYWEEVLLFNEQFSYFLGKQESDPKVVILFEV-KWNVAAA--KRQSRSETDKGWYHVAWAFLKVLGANGSINTDKKVRLQLFYPGRATFRARD-PNVLEVYHWWKLARRVPYPSTLYVTLKGIIPPKEVD-------------------------PGLRDKK--ESTEPTNWTRLPGQVNRIPNKQFLSLRSGQRGCFVVKFSNNGRYLAC-ACADMDSFPVIVYEIP--SGDCSGELPGHFSIIYDLCWSQDDQELMSASSDGTVRIWDTKGMMTTSLK-------------------------ILPHPCFVYAARYHPVATQIVVTGGYDRLLRVWTKDSEGPNGQLLRELGGHSGFVNSICFDSQGTTMFSADSSGCIIIW---QTYLDPATITGRK--KKTAADEL--KGNVINSILLHPGERKLLVHTRNSALYMLDLRSYTIMQRYLGASNFKEHIHSAMSACGSFVFSGSED----GLAYVWNTDTGDIVSIYTSLAYEHAVSDVDFHPLDHLIVFCSFGNSQPVLVYKYNVKGKC 495          

Query: 1510 PTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC---HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGH-KGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTG 2286
            P  T+ GH   + +L+W  K+  L S+S D T ++W + +                                 LC   H  FV A+ FHP  +   ++   D  IR+W+I   K  + ++++G     I  A F L GR    G   G    +     +      +  +W  +S  ++   +G  I+ +   P  +++ + S D  IRL DLK  ++  K+ G  NS   ++   S  G +L  GSED      VY+W  Q G
Sbjct:  266 PFCTYCGHTGDVLDLSWS-KNYFLLSSSMDKTVRLWHISR------------------------------NECLCCFQHIDFVTAIVFHPRDDRYFLSGSLDGKIRLWNIPDKKVALWNEVEGTGSNLITAANFCLQGRFAVIGTYDGRCIFYETERLK------YHTQWQVRSGRNKRS-RGRKISGIEPMPGEEKVLITSNDSRIRLYDLKDNSLYCKYKGCSNSSSQIKASFSHDGQYLICGSED----HFVYIWRTQHG 486          

Query: 1357 PNVPHIKFFTGADGA-NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
            PN       TG + A +++ FS +G WLA  + + +       YD          T  GH   I ++AW   S  L SAS D T K+W               +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   +    F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED     +VY+WN Q+ +   + K  G S  V     HP  ++IA  A+ N+ +I+I+
Sbjct:   53 PNYQLKYTLTGHNKAVSSVKFSHNGEWLASSSADKVIKI-WGAYD-----GKFEKTITGHKLGISDVAWSTDSRHLVSASDDKTLKIWDFAT----------GKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVTAVHFNRDGALIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCVFANFSVTGGKWIVSGSED----HKVYIWNLQSKE--VVQKLDGHSDVVLCCACHPTENIIASGALENDKTIKIW 350          

Query: 2954 VVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYV 3106
            V+ +Y Y+A R+DE++   G++I ++++D +NW +GE  DG+QGY P+NY+
Sbjct:    1 VLVMYPYEANRADELTITPGDVITVLYQDNENWWMGELADGRQGYFPSNYI 51          

Query: 1729 LCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIA 2370
            + H   +  ++  P    +++T G D+ + +W  ++ + ++I  L GH   + C  F+     + +G   G +  W     +L+   I +     +S I  LD           HP G  +   S D +++L D++ K  +  + G  +   +LR   SP G ++ SG ED ++     +W+   G  +  +K    +GPV+  ++HPK  L+A
Sbjct:   15 VAHGSNINCLSLGPSTGRVMVTGGEDRKVNMW--AVGQPNVIMSLAGHTSPVECVQFNSGEDLVVAGSQSGTLKIW-----DLEAAKILRTLTGHKSSIRSLDF----------HPFGDFVASGSLDTNLKLWDIRRKGCIFTYKGHTDCVNHLR--FSPDGRWIISGGEDGAA----KLWDLTAGKIINDFKM--HTGPVNCAEFHPKEFLLA 203          

Query: 1519 TFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLC-HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCC-LSPCGSFLFSGSEDCSSGSQVYVWN 2274
            +  GH   +  + +    +L+ + S  GT K+W                    +EA  +         RTL  H   + ++ FHPF    + +   D  +++WDI   +K  I    GH   +N   FS DGR + SG   G    W +               T+  +I++  +    +N    HP    L   S D +++  DL+   +V            +RC      G  LFSG++D     +VY W 
Sbjct:   56 SLAGHTSPVECVQFNSGEDLVVAGSQSGTLKIW-------------------DLEAAKI--------LRTLTGHKSSIRSLDFHPF-GDFVASGSLDTNLKLWDI--RRKGCIFTYKGHTDCVNHLRFSPDGRWIISGGEDGAAKLWDL---------------TAGKIINDFKMHTGPVNCAEFHPKEFLLATGSSDRTVKYWDLETFELV---SSTSPETHPIRCIGFHTDGLCLFSGAQD---SLKVYGWE 258          

Query:  667 MIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKH----PAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGA---------------PNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIW--DISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYN 2418
            M+++H++D  TG+ + K ++ R   S  E  E V  ILPVMTQPFDF+ R+  +P WEE I+FNE  ++ ++     P V+  FE+LD                 SGF  IAWAFL+ + +NG  N   K+RLQL+   P R K  P +  V  WW++  R  Y STLYVT+ GI+L   +    + RSM   Q+E                 P    DS  P L            +W RLP Q+C IPN   + F  G  G  ++ FS  G+ LA  A  + + FPV++Y++   S      F+GH RI+++L W      L SAS+DGT + W ++K+     K                          L HP FVY   +HP   ++++T  +D ++R+W  D+S     ++ + DGH  FIN   F   G  ++S D  G I  W         ++  +  W ++  ++E +L+GV I+ L +HP G+ L VH+RDG +R++DL+I A V K+ G  N  + +   ++PCG+++FSGSED       YVWNA+TGD VA+Y ELG S  V ++ +HP  +++AF A G    + +Y ++
Sbjct:    1 MVKIHVVDERTGQYVKKDDRRRPAVSFYEG-ENVDHILPVMTQPFDFRRRKSVVPEWEEQILFNERFSHFLQQDECSPKVLLLFEILDFVTMEEARANADADGHESGFRKIAWAFLKLVGANGVRNVDSKLRLQLF-CPPPRAKRQPKTIEVFEWWRKFPRSKYASTLYVTVRGIQLPAHVDP--STRSMMALQEERGSSSYSELQKQVSSRTPPQTADSRQPEL------------RWRRLPGQVCSIPNKHVLGFRGGHMGCFSVLFSNAGSILA-AACADRDAFPVVVYEIP--SGKVLAAFSGHLRIVYDLCWSRDDGRLLSASSDGTVREWNVEKLLGTAQK-------------------------VLPHPSFVYCARYHPSAQNLVVTGSFDFLVRVWRLDVSDVNGQLLQEFDGHSSFINSLCFDSAGTRMFSADNSGLIMVWKTAVSHDGPQSSCRH-WCAEKKLEEAELRGVPISMLQLHPNGRFLLVHARDGLLRMMDLRILA-VKKYLGATNYRERICSTVTPCGTWIFSGSED----GMAYVWNAETGDQVAVYSELGYSSAVHAVVFHPHENMVAFCAFGQGQPVHVYLHD 555          

Query: 2951 EVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTKT 3190
            +VV+L+DY+A RSDE+S  RG++I+++ +D + W  G    G +GY  + YV  +    EQ      D E  +  T T+ 
Sbjct:  692 QVVSLFDYRASRSDELSLRRGDVIQVLHKDNQTWWFGRMRGGLKGYFLSAYVVDQRDFSEQNTDALLDEETATRATPTRV 771          

Query: 1321 QWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIW--DISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCW 1956
            +W RLP Q+C IPN   + F  G  G  ++ FS  G+ LA  A  + + FPV++Y++   S      F+GH RI+++L W      L SAS+DGT + W ++K+     K                          L HP FVY   +HP   ++++T  +D ++R+W  D+S     ++ + DGH  FIN   F   G  ++S D  G I  W
Sbjct:   37 RWRRLPGQVCSIPNKHVLGFRGGHMGCFSVLFSNAGSILA-AACADRDAFPVVVYEIP--SGKVLAAFSGHLRIVYDLCWSRDDGRLLSASSDGTVRCWNVEKLLGTAQK-------------------------VLPHPSFVYCARYHPSAQNLVVTGSFDFLVRVWRLDVSDVNGQLLQEFDGHSSFINSLCFDSAGTRMFSADNSGLIMVW 222          

Query: 2951 EVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVA--GEELLIEQPVSPREDYEQ----NSPGTNTKTRFKD 3202
            +VV+L+DY+A RSDE+S  RG++I+++ +D + W  G    G +GY  + YV    E L  E P    ++Y Q      PG    T+  D
Sbjct:  386 QVVSLFDYRASRSDELSLRRGDVIQVLHKDNQTWWFGRMRGGLKGYFLSAYVVDQSEALPDEDPPPQSQEYSQPEGPRPPGWWRPTQRSD 475          

Query: 1396 GANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCL-----SPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIY 2409
              +++ FSP G WLA  + +       L+            T +GH   I ++AW   S LL SAS D T K+W +             +   T++                 H  +V+   F+P  N ++++  +D+ +RIWD+   K   +  L  H   ++   F+ DG  + S    G    W                 + Q +   +D     ++ +   P GK +   + D +++L D      +  + G     KN + C+        G ++ SGSED    + VY+WN QT +   + K  G +  V S   HP  ++IA  A+ N+ +I+++
Sbjct:   47 AVSSVKFSPSGEWLASSSADK------LIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDV----------NSGKCLKTLKG----------------HSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGK--CLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTA--------------SGQCLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTG----HKNEKYCIFANFSVTGGKWIVSGSED----NMVYIWNLQTKE--IVQKLQGHTDVVISTACHPTENIIASAALENDKTIKLW 330          

Query: 1735 HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIA---------------FTAI----GNESSIQIYTYNSERNCLY 2439
            H   V  +A       +L T G D  + +W  S+NK + I  L GHK  + C  FSL    + +G   G+I  W +                +  ++  L      I  L  HP G+ L   S D +I+L D++ K  V +F G  ++ ++L    SP G +L S S+DC+    V +W+   G  +  +K    S  V+ + +HP  +L+A               FT I    G+ S+I+   ++ + +CL+
Sbjct:   19 HARPVSCLALGKSTGRLLATGGEDCRVNLW--SLNKANCIMSLTGHKTAVECIQFSLSEEQVAAGSQSGSIRVWDL---------------EAAKILQTLMGHKASITSLGFHPYGQFLASSSMDTNIKLWDVRRKGYVFRFKGHTDAVRSL--AFSPDGKWLASASDDCT----VKLWDLSQGKIITEFK--SHSAAVNIVQFHPNEYLLASGSSDRSVRLWDLEKFTMIGTLEGDTSAIRCVCFSPDGSCLF 247          

Query: 1519 TFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRC-CLSPCGSFLFSGSED 2241
            +  GH   +  + +    E +A+ S  G+ +VW             D +    ++               + H   + ++ FHP+    L ++  D  I++WD+   +K  + +  GH   +    FS DG+ L S      +  W + + +               +I E       +N +  HP    L   S D S+RL DL+   M+    G  ++   +RC C SP GS LFSG+ D
Sbjct:   58 SLTGHKTAVECIQFSLSEEQVAAGSQSGSIRVW-------------DLEAAKILQT-------------LMGHKASITSLGFHPY-GQFLASSSMDTNIKLWDV--RRKGYVFRFKGHTDAVRSLAFSPDGKWLASASDDCTVKLWDLSQGK---------------IITEFKSHSAAVNIVQFHPNEYLLASGSSDRSVRLWDLEKFTMIGTLEGDTSA---IRCVCFSPDGSCLFSGATD 252          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMK--KITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAG-YDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSG 1929
             +L F P G +LA  +++      + L+D+ +  +     F GH   + +LA+    + LASAS D T K+W +   KI +E                               H   V  V FHP  N  L+ +G  D+ +R+WD  + K  +I  L+G    I C  FS DG  L+SG
Sbjct:  109 TSLGFHPYGQFLASSSMDTN----IKLWDVRRKGY--VFRFKGHTDAVRSLAFSPDGKWLASASDDCTVKLWDLSQGKIITEFKS----------------------------HSAAVNIVQFHP--NEYLLASGSSDRSVRLWD--LEKFTMIGTLEGDTSAIRCVCFSPDGSCLFSG 249          

Query: 1735 HPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIA---------------FTAI----GNESSIQIYTYNSERNCLY 2439
            H   V  +A       +L T G D  + +W  S+NK + I  L GHK  + C  FSL    + +G   G+I  W +                +  ++  L      I  L  HP G+ L   S D +I+L D++ K  V +F G  ++ ++L    SP G +L S S+DC+    V +W+   G  +  +K    S  V+ + +HP  +L+A               FT I    G+ S+I+   ++ + +CL+
Sbjct:   19 HARPVSCLALGKSTGRLLATGGEDCRVNLW--SLNKANCIMSLTGHKTAVECIQFSLSEEQVAAGSQSGSIRVWDL---------------EAAKILQTLMGHKASITSLGFHPYGQFLASSSMDTNIKLWDVRRKGYVFRFKGHTDAVRSL--AFSPDGKWLASASDDCT----VKLWDLSQGKIITEFK--SHSAAVNIVQFHPNEYLLASGSSDRSVRLWDLEKFTMIGTLEGDTSAIRCVCFSPDGSCLF 247          

Query: 1519 TFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRC-CLSPCGSFLFSGSED 2241
            +  GH   +  + +    E +A+ S  G+ +VW             D +    ++               + H   + ++ FHP+    L ++  D  I++WD+   +K  + +  GH   +    FS DG+ L S      +  W + + +               +I E       +N +  HP    L   S D S+RL DL+   M+    G  ++   +RC C SP GS LFSG+ D
Sbjct:   58 SLTGHKTAVECIQFSLSEEQVAAGSQSGSIRVW-------------DLEAAKILQT-------------LMGHKASITSLGFHPY-GQFLASSSMDTNIKLWDV--RRKGYVFRFKGHTDAVRSLAFSPDGKWLASASDDCTVKLWDLSQGK---------------IITEFKSHSAAVNIVQFHPNEYLLASGSSDRSVRLWDLEKFTMIGTLEGDTSA---IRCVCFSPDGSCLFSGATD 252          

Query: 1402 NTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMK--KITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAG-YDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSG 1929
             +L F P G +LA  +++      + L+D+ +  +     F GH   + +LA+    + LASAS D T K+W +   KI +E                               H   V  V FHP  N  L+ +G  D+ +R+WD  + K  +I  L+G    I C  FS DG  L+SG
Sbjct:  109 TSLGFHPYGQFLASSSMDTN----IKLWDVRRKGY--VFRFKGHTDAVRSLAFSPDGKWLASASDDCTVKLWDLSQGKIITEFKS----------------------------HSAAVNIVQFHP--NEYLLASGSSDRSVRLWD--LEKFTMIGTLEGDTSAIRCVCFSPDGSCLFSG 249          

Query:   40 MSVVIQNPVPRARRTPRKSKEANILEPKVDDIELNDAKVLNDIRQSIEKSESNNDLKNNLYEQEVPDKMXXXXXXXXXXLDGKDNPSFEPDIVVEENLKENSIMXXXXXXXXXXXXXXXXXXXXXTNNEEISNPVSNENQEVINAEQDADGGVKPRRRRPKQDKIETKTDSQEIEKDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKFRRVTIPAWEESIIFNENSNYLMKHPAVIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELD 2037
            MSVVIQNPVPRARRTPRKSKEANILEPKVDDIELNDAKVLNDIRQSIEKSESNNDLKNNLYEQEVPDKMEKRRRRRKEKLDGKDNPSFEPDIVVEENLKENSIMRLEEEEKPRRRRRKHHREEVETNNEEISNPVSNENQEVINAEQDADGGVKPRRRR KQDKIETKTDSQEIEKDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFK RRVTIPAWEESIIFNENSNYLMKHPA+IYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFS DGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKI  EKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELD
Sbjct:    1 MSVVIQNPVPRARRTPRKSKEANILEPKVDDIELNDAKVLNDIRQSIEKSESNNDLKNNLYEQEVPDKMEKRRRRRKEKLDGKDNPSFEPDIVVEENLKENSIMRLEEEEKPRRRRRKHHREEVETNNEEISNPVSNENQEVINAEQDADGGVKPRRRRRKQDKIETKTDSQEIEKDTDPLLIEDDGRVLSIMIHRTDRLKTDLNVLHPMIRVHIIDISTGKPIIKQNKDRKVTSCNEDIEQVTTILPVMTQPFDFKSRRVTIPAWEESIIFNENSNYLMKHPAIIYFFEVLDLNPAYSIDKTFPVQQESSGFHHIAWAFLRPISSNGDLNTGHKVRLQLYENGPHRPKNSPYSSNVVFWWQQRFRQFYPSTLYVTIAGIKLSPEISSEFAMRSMFPNQKEGAPNGLVDSHLPGLALNKHLDVSALSQWMRLPSQMCHIPNVPHIKFFTGADGANTLAFSTDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKIAFEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELD 666          

Query: 2483 EAQVDIGASISPKLQSKNPLIHQDNMTKLDETTFKSRTFEQDENEFKSFKLEMERKHTSRITRILNTLNTVTEVDRTLKATNRSLERNNYSTRNNLNDGYTSGPEDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPPASKHKEQSLKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTKTRFKDEYLEVMNDINPHSTLNSINKE 3265
            +AQVDIGASISPKLQSKNP IHQDNMTKLDETTFKSRTFEQDENEFKSFKLEMERKHTSRITRILNTLNTVTEVDRTL+ATNRSLERNNYSTRNNLNDGYTSGPEDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPP ASKHKEQS KYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTKTRFKDEYLEVMNDINPHSTLNSINKE
Sbjct:  120 QAQVDIGASISPKLQSKNPFIHQDNMTKLDETTFKSRTFEQDENEFKSFKLEMERKHTSRITRILNTLNTVTEVDRTLRATNRSLERNNYSTRNNLNDGYTSGPEDKGRLMRSSKKGSTLQTIPMTLDMTSTSKANFTFKPPSASKHKEQSAKYLGEVVALYDYQAQRSDEISFARGEMIKIVFRDGKNWLLGETCDGKQGYLPANYVAGEELLIEQPVSPREDYEQNSPGTNTKTRFKDEYLEVMNDINPHSTLNSINKE 380          

Query: 2068 MHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNSER 2427
            MHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNSE+
Sbjct:    1 MHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGPVSSIDYHPKCHLIAFTAIGNESSIQIYTYNSEQ 120          

Query: 1408 LAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFV-NSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSVPEFELKNEAIFKEKWTSQSVIDELDLKGVIINHLIMHPTGKRLFVHSRDG-SIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPC------GSFLFSGSED 2241
            +  S DG +   G+ +      + L+DLT  S   T  F GH + + ++A+   +  + S S DGT K+W    +              TI+ D               H  +V  V F P   N  +++ G+DK++++W++S  K    H   GH G++N    S DG    SG   G    W + E         +  +T +         G IIN LI  P   R ++ +  G SI++ DL+ K +V      V   K+       C      G  LF+G  D
Sbjct:   69 VVMSSDGQFALSGSWDG----TLRLWDLT--SGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDGTIKLWNTLGVCKY-----------TIQEDG--------------HTDWVSCVRFSPTSENPSIVSCGWDKVVKVWNLSNCKLRTNHF--GHNGYLNTVAVSPDGSLCASGGKDGQAMLWDLSE--------GRHLYTLEG--------GDIINALIFSP--NRYWLCAATGSSIKIWDLENKVLVGDLKAEVIDNKSKATAEVTCLSWSQDGQTLFAGYSD 303          

Query: 1363 VPHIKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSF-----GDK-------------RTLCHPCF--VYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWSV 1962
            + HI+   G D  +TL  S D   +   +  N+NN       +  +S        GH   ++++AW      + +AS+DGT ++W M   T+        +    +  D  PV G +      D+             R     C+  V  V FH  VN +  +   D+++R++DI      ++    GHKG +NC  FS DGR L SG   G+++ W +
Sbjct:  378 ILHIRCLNG-DNMSTLKSSDDLGQIIL-SDPNINNRI-----MANMSGAVYKELKGHAGGVYDIAWSTDRNQVLTASSDGTVRLWCMMTWTNLAKYQDGGEPLWAV--DFAPVYGHYLATGGNDRCVNLYAADNLKPLRRFVGDCYGPVTCVKFHNNVNYV-ASGSTDRVVRLFDIR--SGGMVRSFTGHKGTLNCLQFSDDGRFLLSGCDAGSVNIWDL 585          

Query: 1372 IKFFTGADGANTLAFSPDGAWLACGAIENMNNFPVLLYDLTKLSHHPTNTFNGHNRIIHNLAWCHKSELLASASADGTCKVWRMKKITSEKDKNRDNQTTNTIEADTVPVGGSFGDKRTLCHPCFVYAVAFHPFVNSILITAGYDKIIRIWDISINKKDIIHQLDGHKGFINCALFSLDGRTLYSGDAKGNIHCWS----------------VPEFELKNEAIFKEKWTSQSVIDELDLK-----------GVIINHLIMHPTGKRLFVHSRDGSIRLIDLKIKAMVVKFHGIVNSEKNLRCCLSPCGSFLFSGSEDCSSGSQVYVWNAQTGDHVAIYKELGLSGP 2328
            + F    D    + F+P+ + LA G I++     +++++    +      F GH   I ++ +    +L+ASAS D T ++W                   +I+ +++         R++   C           N  ++T   DK I++W   ++++   + L+ HK ++ C  FS DG+ + S      I  W                 VP         +     + S ++  D++              +N +  HP+G  L   S D S+++ DL    ++    G  +    L    S CG    SG  D     QV++W A       I    G S P
Sbjct:    8 VHFKGHKDKVTCVDFNPNSSQLASGGIDSC----LMIWNFKPQTR--AYRFVGHEDAILSVKFSPTGQLVASASRDKTVRLW-----------------VPSIKGESLVFRAHTATVRSVDISC----------DNLEMVTGSDDKTIKVW--KMHRQKFSYSLNEHKNWVRCVRFSSDGQLIASSSDDKTIKLWDRHNQECIHTFQEHGGFVPSLAFHPNGSYIASGGTDSHVNIWDIRMNKLLQHYTSHTSPVNAVSFHPSGNFLISSSDDSSMKIYDLLEGRLLYTVQG--HEGPILGTAFSHCGEMFASGGAD----HQVFLWQAGQLSEPGIAVHSGSSQP 312