MFS domain-containing protein
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppSub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035820 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 3
Homology
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]) HSP 1 Score: 58.151 bits (139), Expect = 7.686e-9 Identity = 49/176 (27.84%), Postives = 91/176 (51.70%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYN 574 KS+++ I FL+ + +V++ ++W Y K+ P+ + + GW +A++++ ++ P+FG + R K L++S + + N +Y ASH + +L+ R L G GAG + + TSLQERT + + + + G I+GPA T + + I QV++ N Sbjct: 33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPASTDEAQVPQGNIDQVAVVAIN 206
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]) HSP 1 Score: 58.151 bits (139), Expect = 7.686e-9 Identity = 49/176 (27.84%), Postives = 91/176 (51.70%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYN 574 KS+++ I FL+ + +V++ ++W Y K+ P+ + + GW +A++++ ++ P+FG + R K L++S + + N +Y ASH + +L+ R L G GAG + + TSLQERT + + + + G I+GPA T + + I QV++ N Sbjct: 33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPASTDEAQVPQGNIDQVAVVAIN 206
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]) HSP 1 Score: 56.9954 bits (136), Expect = 1.530e-8 Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS+++ I FL+ + +V++ ++W Y K+ P+ + + GW +A++++ ++ P+FG + R K L++S + + N +Y ASH + +L+ R L G GAG + + TSLQERT + + + + G I+GP C + K + + ++ I++Y P LL A Sbjct: 33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]) HSP 1 Score: 56.9954 bits (136), Expect = 1.541e-8 Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS+++ I FL+ + +V++ ++W Y K+ P+ + + GW +A++++ ++ P+FG + R K L++S + + N +Y ASH + +L+ R L G GAG + + TSLQERT + + + + G I+GP C + K + + ++ I++Y P LL A Sbjct: 33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486]) HSP 1 Score: 56.9954 bits (136), Expect = 1.541e-8 Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS+++ I FL+ + +V++ ++W Y K+ P+ + + GW +A++++ ++ P+FG + R K L++S + + N +Y ASH + +L+ R L G GAG + + TSLQERT + + + + G I+GP C + K + + ++ I++Y P LL A Sbjct: 33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: Y53G8AR.7 (pep chromosome:WBcel235:III:3282308:3290215:1 gene:WBGene00021814.1 transcript:Y53G8AR.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y53G8AR.7) HSP 1 Score: 59.3066 bits (142), Expect = 3.391e-9 Identity = 55/228 (24.12%), Postives = 101/228 (44.30%), Query Frame = 2 Query: 101 GFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIY-FIASHP-----WMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDI---KMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIID 757 G G++ ++ PTLW + + V P+ ++ ++G+ AAF+V L P+FGY V+ LV + I+ NII+ F+ + W++++ RF G GAG + A +SL++R I + G+ +GP + I + G +D+Y P +++ + V+ I+ L+ + L + + EDS+ D I Sbjct: 55 GMFCGIQFSIFFPTLWPFLNTV-DPTASASFFGFITAAFSVGQGLASPVFGYWMNKAKSVRQPLVFGISVMILSNIIFCFVEAFAEKERRWVMMVARFFIGVGAGTIGVMRAYAATASSLKDRARAITFIQASYVIGMTLGPGIQVAFTPIGYPGLSKGVFHVDMYTSPAWFASII---SLLSVIFIFIFLEENYAGLDQ----------GADTEDSYTAMPTFDTIS 268
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179]) HSP 1 Score: 144.05 bits (362), Expect = 2.657e-37 Identity = 132/441 (29.93%), Postives = 221/441 (50.11%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFL-TGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY---PRLKS--DRQNLSKSDRVPLLTPMSMELEDSHR----KSYCS---DIIDAQLKQGIEELPSPTTMERISN-FFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336 + K K+ FI FL +G+E AVI+PT+W Y + +P ++ G L+AF+ + L+ P+FG+ + KT+++ SN I+GN +YF+ W++L R +AG GAG ++ + R T ER ++ RQ GL+IGPA + ++ K+G ++ Y PGL + +W V+ +Y P L S ++Q + R P+ M LED R SY S + + QL I P + S+ F N +++L+ ++ L F + F+ LE+++ P+ +YF + E+ S +Y CGV VI + ++R + SR +EDR +L GL++ + + +W CL + Q L L +IG+ +LG PF SL++K Q +Q + R V +A ++GP G + Sbjct: 4 RQKRKLSFITIGLTFLLSGIEYAVILPTIWRYLQLLEAPP---YFLGLGLSAFSFSGLVTGPVFGHWSDKTRTTKTIILFSNVFEIVGNFMYFMGYSKWLLLSSRLVAGIGAGAGSSIFGFLTRTTLPDERARVFAAVMACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGLFMCGMWLLMQFAVMGLYWDIPPLDSFAEQQMPLREVRGEEDEPL-MSLEDDDRTAVADSYGSLNPEQTETQLSSQIPPSPPESPPPDTSDPFENFSASREFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWL-SRVLEDRVVLAVGLLICSGACVW---CLIFLANPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 436
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01045212.1 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:564731]) HSP 1 Score: 129.413 bits (324), Expect = 3.819e-32 Identity = 113/416 (27.16%), Postives = 198/416 (47.60%), Query Frame = 2 Query: 125 AVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVP-------LLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETE 1345 AVI+PT+W Y + + A ++ G +L+AF+ + LL PLFG+ + + K +++ +N I+GN +YF+ W++L R +AG G G ++ + R T+ ++R+ ++ RQ GL+IGP L ++ ++G ++ Y PGL + +LW ++V+ +Y + + + +S R P + L + S ID + + F ++L+ ++ L F + F+ LE+++ P+ ++F + E+E S +Y CGV VI ++ +R S R E R +L GLIL IS +W CL + Q L +IG+ VLG PF SL++K Q +Q I R V +A ++GP G + + Sbjct: 35 AVILPTIWRYLQTL---NAAPYFLGLSLSAFSFSGLLAGPLFGHWSDRTLTTKKIILFANIFEIVGNFMYFMGFSKWLLLSSRLVAGIGTGAGSSIFGFLTRNTAPEDRSTVFAAVMACRQAGLLIGPGFNLFLRLCDFEMGPFIVNKYTAPGLFMCLLWILLQLVVVFMYWDISPEDER--RSQRSPEQEEEEEEEEEEAKPLVGPNELSGSYGTIDLMCVCVCVCVCVCVCVCVCVCVF---LLSEFLREEVVVLLAAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFLFVRWFSKRAAE-RVVLAVGLILCNISCVW---CLIFLANPQGGFAWQLAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGIRRSVGGLATILGPLWAGGLTSN 438
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01045212.1 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:564731]) HSP 1 Score: 93.9745 bits (232), Expect = 3.287e-20 Identity = 56/193 (29.02%), Postives = 106/193 (54.92%), Query Frame = 2 Query: 110 TGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVP 688 T L +VI+PT+W Y + + A ++ G +L+AF+ + LL PLFG+ + + K +++ +N I+GN +YF+ W++L R +AG G G ++ + R T+ ++R+ ++ RQ GL+IGP L ++ ++G ++ Y PGL + +LW ++V+ +Y + + + +S R P Sbjct: 1 TLLSISVILPTIWRYLQTL---NAAPYFLGLSLSAFSFSGLLAGPLFGHWSDRTLTTKKIILFANIFEIVGNFMYFMGFSKWLLLSSRLVAGIGTGAGSSIFGFLTRNTAPEDRSTVFAAVMACRQAGLLIGPGFNLFLRLCDFEMGPFIVNKYTAPGLFMCLLWILLQLVVVFMYWDISPEDER--RSQRSP 188 HSP 2 Score: 59.6918 bits (143), Expect = 3.801e-9 Identity = 49/147 (33.33%), Postives = 74/147 (50.34%), Query Frame = 2 Query: 911 GLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETE 1345 LE+++ P+ ++F + E+E S +Y CGV VI ++ +R S R E R +L GLIL IS +W CL + Q L +IG+ VLG PF SL++K Q +Q I R V +A ++GP G + + Sbjct: 264 ALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFLFVRWFSKRAAE-RVVLAVGLILCNISCVW---CLIFLANPQGGFAWQLAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGIRRSVGGLATILGPLWAGGLTSN 406
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179]) HSP 1 Score: 83.1889 bits (204), Expect = 4.472e-17 Identity = 87/300 (29.00%), Postives = 145/300 (48.33%), Query Frame = 2 Query: 482 RQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY---PRLKS--DRQNLSKSDRVPLLTPMSMELEDSHR----KSYCS---DIIDAQLKQGIEELPSPTTMERISN-FFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336 RQ GL+IGPA + ++ K+G ++ Y PGL + +W V+ +Y P L S ++Q + R P+ M LED R SY S + + QL I P + S+ F N +++L+ ++ L F + F+ LE+++ P+ +YF + E+ S +Y CGV VI + ++R + SR +EDR +L GL++ + + +W CL + Q L L +IG+ +LG PF SL++K Q +Q + R V +A ++GP G + Sbjct: 4 RQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGLFMCGMWLLMQFAVMGLYWDIPPLDSFAEQQMPLREVRGEEDEPL-MSLEDDDRTAVADSYGSLNPEQTETQLSSQIPPSPPESPPPDTSDPFENFSASREFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWL-SRVLEDRVVLAVGLLICSGACVW---CLIFLANPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 298
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:564342]) HSP 1 Score: 63.1586 bits (152), Expect = 3.494e-10 Identity = 60/248 (24.19%), Postives = 118/248 (47.58%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASHPWM-VLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMK-----DIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQ-------NLSKSDRVPLLTPMSMELEDSHRKSYCSDII 754 +S+++ + F FL+ + ++I ++W Y K+ + AS + GW +AA+++ ++ P FG + R + LV S + + NI +Y SH + +LL R G GAG + + + TSL+ERT + + + G I+GPA ++ + + + ++ +++Y P LL A + +LV+L+ D N + +RV + P +E + H + S+++ Sbjct: 25 RSRWRSIRVMYFTMFLSSVGFTIVITSIWPYLKKIDESADAS-FLGWVVAAYSLGQMVASPFFGLWSNHRPR-REPLVCSIFINVSANIYYSYVYLPPSHNQIHMLLARTFVGIGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAVLSFIGETGVSVDVIKLQVNMYTAPALLAACFGVINILLVILVLREHSVDDHGNRIRPINYTPEERVDV--PPEVEGDIDHIAVFTSNVL 268
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683]) HSP 1 Score: 140.584 bits (353), Expect = 8.614e-36 Identity = 116/432 (26.85%), Postives = 210/432 (48.61%), Query Frame = 2 Query: 86 IAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSH------RKSYCSDIIDAQLKQGIEELPSPTTMERISNFF-----------NPINYK--DYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPN--LFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGP 1318 + F L G+E AVI+PT+W+Y + + + G L+A + LL PLFGY + + K ++++SN I GN++YF+ W +L R +AG G+G ++ + R +S +ER + + RQ GL+IGPA + ++ +IG +D ++ PG+ + LW LVL ++ +K Q ++ PLL E + ++ +D + + L S ++ME I + +N + L+ ++ L F F+ LE+++ P+A Y + +++ S +Y CG+ +++ ++++R + R DR LL+ GL + IS +W CL + K + + L ++ V+G+ VLG PF +C SL++K Q + R V +A ++GP Sbjct: 30 VIGFIFLLNGIEYAVILPTIWMYLQSLDAEPV---FLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEPEDLGKKSLNDRLSGLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRAL-GRCTSDRLLLIFGLFVCNISCIW---CLVFMAKPRGSYGLLLAEFVVGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGP 454
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683]) HSP 1 Score: 140.198 bits (352), Expect = 8.708e-36 Identity = 117/432 (27.08%), Postives = 209/432 (48.38%), Query Frame = 2 Query: 86 IAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSH------RKSYCSDIIDAQLKQGIEELPSPTTMERISNFF-----------NPINYK--DYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPN--LFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGP 1318 + F L G+E AVI+PT+W+Y S + G L+A + LL PLFGY + + K ++++SN I GN++YF+ W +L R +AG G+G ++ + R +S +ER + + RQ GL+IGPA + ++ +IG +D ++ PG+ + LW LVL ++ +K Q ++ PLL E + ++ +D + + L S ++ME I + +N + L+ ++ L F F+ LE+++ P+A Y + +++ S +Y CG+ +++ ++++R + R DR LL+ GL + IS +W CL + K + + L ++ V+G+ VLG PF +C SL++K Q + R V +A ++GP Sbjct: 21 VIGFIFLLNGIEYAVILPTIWMYLQ---SLDAEPVFLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEPEDLGKKSLNDRLSGLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRAL-GRCTSDRLLLIFGLFVCNISCIW---CLVFMAKPRGSYGLLLAEFVVGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGP 445
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683]) HSP 1 Score: 137.502 bits (345), Expect = 5.904e-35 Identity = 112/421 (26.60%), Postives = 205/421 (48.69%), Query Frame = 2 Query: 125 AVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSH------RKSYCSDIIDAQLKQGIEELPSPTTMERI---------------SNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPN--LFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGP 1318 AVI+PT+W+Y + + + G L+A + LL PLFGY + + K ++++SN I GN++YF+ W +L R +AG G+G ++ + R +S +ER + + RQ GL+IGPA + ++ +IG +D ++ PG+ + LW LVL ++ +K Q ++ PLL E + ++ +D + + L S ++ME I + + ++ K L+ ++ L F F+ LE+++ P+A Y + +++ S +Y CG+ +++ ++++R + R DR LL+ GL + IS +W CL + K + + L ++ V+G+ VLG PF +C SL++K Q + R V +A ++GP Sbjct: 26 AVILPTIWMYLQSLDAEPV---FLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEPEDLGKKSLNDRLSGKRLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRAL-GRCTSDRLLLIFGLFVCNISCIW---CLVFMAKPRGSYGLLLAEFVVGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGP 439
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:100495784]) HSP 1 Score: 60.4622 bits (145), Expect = 3.457e-9 Identity = 53/194 (27.32%), Postives = 101/194 (52.06%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTL---LMKDIKMKIGQV--SIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSD 655 FL+ + ++++ ++W Y KV + AS + GW +A+F++ ++ PLFG + R + LV+S + + + +Y ASH + +LL R L G G+G + + + TSL ERT + + F+ G I+GPA ++ + + IG + +++Y P L+ A+L + IL+ ++ + D Sbjct: 45 FLSSVGFSIVMTSIWPYLQKVDQSADAS-FLGWVIASFSLGQMVASPLFGLWSNHRPR-REPLVVSITILVAASCLYAYVQVPASHNKYYMLLARTLVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAIGFILGPAFQAGLSMIGENGVTIGAIYLQVNMYTAPALMGALLGIGNIILIFAVFREHRVD 236
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:100495784]) HSP 1 Score: 60.077 bits (144), Expect = 4.792e-9 Identity = 53/194 (27.32%), Postives = 101/194 (52.06%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTL---LMKDIKMKIGQV--SIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSD 655 FL+ + ++++ ++W Y KV + AS + GW +A+F++ ++ PLFG + R + LV+S + + + +Y ASH + +LL R L G G+G + + + TSL ERT + + F+ G I+GPA ++ + + IG + +++Y P L+ A+L + IL+ ++ + D Sbjct: 45 FLSSVGFSIVMTSIWPYLQKVDQSADAS-FLGWVIASFSLGQMVASPLFGLWSNHRPR-REPLVVSITILVAASCLYAYVQVPASHNKYYMLLARTLVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAIGFILGPAFQAGLSMIGENGVTIGAIYLQVNMYTAPALMGALLGIGNIILIFAVFREHRVD 236
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425]) HSP 1 Score: 60.077 bits (144), Expect = 3.400e-9 Identity = 54/188 (28.72%), Postives = 95/188 (50.53%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS++K I FL+ + +++I ++W Y K+ + AS + GW +A++++ ++ PLFG + R K L++S + + N +Y A + + +L+ R L G GAG + + I TSLQERT + + G I+GP C L+ K + I ++ +++Y P LL A Sbjct: 34 KSRWKSVRILYLTMFLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 219
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425]) HSP 1 Score: 60.077 bits (144), Expect = 3.400e-9 Identity = 54/188 (28.72%), Postives = 95/188 (50.53%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS++K I FL+ + +++I ++W Y K+ + AS + GW +A++++ ++ PLFG + R K L++S + + N +Y A + + +L+ R L G GAG + + I TSLQERT + + G I+GP C L+ K + I ++ +++Y P LL A Sbjct: 34 KSRWKSVRILYLTMFLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 219
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425]) HSP 1 Score: 57.3806 bits (137), Expect = 3.430e-9 Identity = 50/174 (28.74%), Postives = 89/174 (51.15%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 FL+ + +++I ++W Y K+ + AS + GW +A++++ ++ PLFG + R K L++S + + N +Y A + + +L+ R L G GAG + + I TSLQERT + + G I+GP C L+ K + I ++ +++Y P LL A Sbjct: 2 FLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 173
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425]) HSP 1 Score: 57.3806 bits (137), Expect = 3.430e-9 Identity = 50/174 (28.74%), Postives = 89/174 (51.15%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 FL+ + +++I ++W Y K+ + AS + GW +A++++ ++ PLFG + R K L++S + + N +Y A + + +L+ R L G GAG + + I TSLQERT + + G I+GP C L+ K + I ++ +++Y P LL A Sbjct: 2 FLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 173
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0VA82|MFSD8_DANRE (Major facilitator superfamily domain-containing protein 8 OS=Danio rerio OX=7955 GN=mfsd8 PE=2 SV=1) HSP 1 Score: 63.1586 bits (152), Expect = 2.638e-9 Identity = 60/248 (24.19%), Postives = 118/248 (47.58%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASHPWM-VLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMK-----DIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQ-------NLSKSDRVPLLTPMSMELEDSHRKSYCSDII 754 +S+++ + F FL+ + ++I ++W Y K+ + AS + GW +AA+++ ++ P FG + R + LV S + + NI +Y SH + +LL R G GAG + + + TSL+ERT + + + G I+GPA ++ + + + ++ +++Y P LL A + +LV+L+ D N + +RV + P +E + H + S+++ Sbjct: 25 RSRWRSIRVMYFTMFLSSVGFTIVITSIWPYLKKIDESADAS-FLGWVVAAYSLGQMVASPFFGLWSNHRPR-REPLVCSIFINVSANIYYSYVYLPPSHNQIHMLLARTFVGIGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAVLSFIGETGVSVDVIKLQVNMYTAPALLAACFGVINILLVILVLREHSVDDHGNRIRPINYTPEERVDV--PPEVEGDIDHIAVFTSNVL 268
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BH31|MFSD8_MOUSE (Major facilitator superfamily domain-containing protein 8 OS=Mus musculus OX=10090 GN=Mfsd8 PE=2 SV=1) HSP 1 Score: 60.077 bits (144), Expect = 2.378e-8 Identity = 54/188 (28.72%), Postives = 95/188 (50.53%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS++K I FL+ + +++I ++W Y K+ + AS + GW +A++++ ++ PLFG + R K L++S + + N +Y A + + +L+ R L G GAG + + I TSLQERT + + G I+GP C L+ K + I ++ +++Y P LL A Sbjct: 34 KSRWKSVRILYLTMFLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 219
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6GPQ3|MFSD8_XENLA (Major facilitator superfamily domain-containing protein 8 OS=Xenopus laevis OX=8355 GN=mfsd8 PE=2 SV=1) HSP 1 Score: 59.3066 bits (142), Expect = 4.486e-8 Identity = 55/202 (27.23%), Postives = 104/202 (51.49%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLMKDIKMKIGQVS--IDIYNGPGLLLAVLWGFHTILVLLIYPRLKSD--RQNLSK 673 FL+ + ++++ ++W Y KV + AS + GW +A+F++ ++ PLFG + R + LV+S + + + +Y ASH + +LL R G G+G + + + TSL ERT + + F+ G I+GP A ++ + + I +S +++Y P L+ A+L + IL+ I+ + D +N+S Sbjct: 45 FLSSVGFSIVMTSIWPYLQKVDQSADAS-FLGWVIASFSLGQMVASPLFGLWSNHRPR-REPLVVSITILVAASCLYAYVHVPASHNKYYMLLARTFVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAMGFILGPAFQAALSVIGETGITINGISLQVNMYTAPALMGALLGIGNIILIFAIFREHRVDDLEKNVSS 244
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NHS3|MFSD8_HUMAN (Major facilitator superfamily domain-containing protein 8 OS=Homo sapiens OX=9606 GN=MFSD8 PE=1 SV=1) HSP 1 Score: 56.225 bits (134), Expect = 4.446e-7 Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595 KS+++ I FL+ + +V++ ++W Y K+ P+ + + GW +A++++ ++ P+FG + R K L++S + + N +Y ASH + +L+ R L G GAG + + TSLQERT + + + + G I+GP C + K + + ++ I++Y P LL A Sbjct: 33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1I8HRG6 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 338.576 bits (867), Expect = 8.848e-108 Identity = 203/439 (46.24%), Postives = 281/439 (64.01%), Query Frame = 2 Query: 65 SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIG-VRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELP------SPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360 +K ++ I + WG LTG+ERA+I+PTLWLYF F S A +YG TLAAFN++ L+C PLFG+L+ VRVK LL+ +NQL I GN++YF+A PW++ LGRF+AG GAG E PLYAD+VRVT+ +ERT IV LLL RQFGLI GPA TLLM ++ K+ + ID+YN PGL +A+LW HTI ++ IYP + R D V S + +S D + Q E P E + F+ K YLK + LF+ FSSYF+LM LE+VLPP A+RYF W E TS VYLG G+ VI VY++++ +S++ EDR LLL+G+ +L +Y W + L +++ +P L+I+L+++GI HV+G PF + ESLYTK V VG+ D AQ + R VI +++L+GP +GGS++ +VF Sbjct: 34 AKLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTISHSRFAGGNGDEV---AAESTDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAK-FEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGSLQFVPWLVF 468
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267FNL8 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006869g2 PE=4 SV=1) HSP 1 Score: 338.576 bits (867), Expect = 3.644e-107 Identity = 201/432 (46.53%), Postives = 278/432 (64.35%), Query Frame = 2 Query: 65 SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIG-VRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELP------SPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSME 1339 +K ++ I + WG LTG+ERA+I+PTLWLYF F S A +YG TLAAFN++ L+C PLFG+L+ VRVK LL+ +NQL I GN++YF+A PW++ LGRF+AG GAG E PLYAD+VRVT+ +ERT IV LLL RQFGLI GPA TLLM ++ K+ + ID+YN PGL +A+LW HTI ++ IYP + R D V S + +S D + Q E P E + F+ K YLK + LF+ FSSYF+LM LE+VLPP A+RYF W E TS VYLG G+ VI VY++++ +S++ EDR LLL+G+ +L +Y W + L +++ +P L+I+L+++GI HV+G PF + ESLYTK V VG+ D AQ + R VI +++L+GP +GGS++ Sbjct: 40 AKLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTISHSRFAGGNGDEV---AAESTDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAK-FEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGSLQ 467
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267GD89 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006869g1 PE=4 SV=1) HSP 1 Score: 336.265 bits (861), Expect = 2.380e-106 Identity = 200/431 (46.40%), Postives = 277/431 (64.27%), Query Frame = 2 Query: 65 SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIG-VRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELP-----SPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSME 1339 +K ++ I + WG LTG+ERA+I+PTLWLYF F S A +YG TLAAFN++ L+C PLFG+L+ VRVK LL+ +NQL I GN++YF+A PW++ LGRF+AG GAG E PLYAD+VRVT+ +ERT IV LLL RQFGLI GPA TLLM ++ K+ + ID+YN PGL +A+LW HTI ++ IYP + R D V S + +S D + Q E P E + F+ K YLK + LF+ FSSYF+LM LE+VLPP A+RYF W E TS VYLG G+ VI VY++++ +S++ EDR LLL+G+ +L +Y W + L +++ +P L+I+L+++GI HV+G PF + ESLYTK V VG+ D AQ + R VI +++L+GP +GG ++ Sbjct: 40 AKLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTISHSRFAGGNGDEV---AAESTDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAK-FEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGLLQ 466
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A448XFL8 (Uncharacterized protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS28931 PE=4 SV=1) HSP 1 Score: 328.561 bits (841), Expect = 4.255e-103 Identity = 197/441 (44.67%), Postives = 283/441 (64.17%), Query Frame = 2 Query: 56 VGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPR-------LKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEEL----PSPTTMERISNFFNP--INYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSME 1339 VG KF I F AA WGFLT +ER+VI+ TL+LYF ++ A ++YG T++AF++AIL+ P+FG LA G+RVK +L++S+QL I+GN++Y I + PW+VLLGRF++GAGA CE PLYADI RVTSL+ERTP IVT+L+ RQ GL+ GPA TL++ ++ + I S+ +YNGPGLL+A LW HT++VLL YP + S L+ D + + + SY ++ QL E+ PS T SN+ + + Y Y++++ + F+ YF M LE+VLPP+A+RYF W E+E S+VYLG G V++ +L + ++ DR+L+L+G L +SY+WL++C + + + I L +IGI HV G P +CSESLY+K V V D +RAQ+ILR VINVA L+GPF GG++ Sbjct: 49 VGSPKFWISFSAATWGFLTSVERSVILSTLFLYFKTYWNAEAAQNFYGATMSAFSLAILIMTPVFGLLAHAGLRVKVILLLSDQLEIVGNLLYLIGTSPWLVLLGRFISGAGASCEPPLYADIARVTSLEERTPIIVTILVSRQCGLMFGPAFTLILHNMNVTIAGFSLSVYNGPGLLMAGLWILHTLVVLLTYPNIDDVGRVIDSSLNKLTSRDLQNCCSCYQTCPQAAGSSSY-NETGSLQLSDCAEDTHLIPPSDETTGGQSNYCRCGLASLRPYSAYNLVTMYAVSFAVYFCFMSLEAVLPPVANRYFDWNEVEVSYVYLGAGGLVLVFCAVLHFL-TQCCSDRSLVLAGCATLVVSYIWLAVCCATLTTAPLSTAIPLTMIGIAIHVAGMPLATACSESLYSKLVKVVDMNRAQAILRTVINVAFLLGPFFGGTLH 487
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A0X3PDP8 (Putative MFS-type transporter C330.07c OS=Schistocephalus solidus OX=70667 GN=YJ87 PE=4 SV=1) HSP 1 Score: 318.931 bits (816), Expect = 9.725e-100 Identity = 192/440 (43.64%), Postives = 280/440 (63.64%), Query Frame = 2 Query: 41 NCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360 N + K+ I FIA+ WGFLT +ERA+I+PT+WLYF + A +YG TLAAF+++IL+ PLFGY V V+ LL+ +N + +IGN+ Y + PW V GR +AG GA CE P+YAD+ R T ERTPYI+ LLL RQ GLIIGPA TL+++ I ++IG V I +YNGPGL++AVLW HT+L+ YP +L KS + +E+ S ++A LK + PS + ++ +++ Y +Y I++ F+IFS+YF +M LESVL P+A+R+F+W E+E S+VY+G V VI+V ++ L+ +R +EDR L+L GL LT+SY +LS L + L +L+V+G+ HV+G PF ++ +ESLYTK + D+AQ+ILR +INVA L+GP+VGGS++ + +VF Sbjct: 63 NVVRHKRPPKYAIAFIASTWGFLTNVERAIILPTMWLYFRDYWGDEVAKSFYGSTLAAFSLSILVTTPLFGYAGHANVNVRHLLMFANFMEVIGNVAYLLPYSPWFVFFGRLIAGVGASCESPMYADLTRTTEESERTPYIIILLLSRQVGLIIGPAFTLILRQITIEIGPVQISVYNGPGLVMAVLWVVHTMLIFFTYP-------HLDKSGEL---------VEELQSGEVASSPVEASLKHSRQ--PSDSRIQ--------VSFAGYGQYHIVTLYFVIFSAYFCVMSLESVLSPVANRFFKWNEVEVSYVYIGSSVLVIIVSGLMHLM-TRCMEDRALVLLGLFFLTVSYAFLSFVLHNVLTMTKTLGATLVVVGVAIHVIGMPFPLAITESLYTKFIPSHQLDKAQTILRTIINVAFLLGPYVGGSLQGKPTIVF 475
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179]) HSP 1 Score: 120.939 bits (302), Expect = 1.717e-29 Identity = 115/415 (27.71%), Postives = 199/415 (47.95%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPG--LLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336 FL+G+E AVI+PT+W Y + +P+ ++ G L+AF+ + LL PLFG + + K++++ SN I+GN +YF+ W++L R +AG GAG ++ + R T ER ++ RQ GL+IGPA + ++ K+G ++ Y PG LL + V + + SD + + VPLL+ L P+ + FF + ++L+ ++ L F + F+ LE+++ P+ +YF + E+ S +Y CGV VI + ++R + SR +EDR +L GL++ + +W C+ + Q + L +IG+ +LG PF SL++K Q +Q + R V +A ++GP G + Sbjct: 19 FLSGVEYAVILPTIWKYLQILDAPA---YFLGLGLSAFSFSGLLSGPLFGRWSDVTRTTKSIILFSNVFEIVGNFMYFLGYSKWLLLASRLVAGIGAGAGSSIFGFLTRTTLPDERARVFAAVMACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGCVFLLCEKSVCVCVCVSVCVCVIYSDILFIDQCP-VPLLS-----------------------------LFPPSLYFSLVFFF----FSEFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIGGFFLVRWL-SRVLEDRAVLAVGLLICCGACVW---CIIFLASPQGGFAVELTEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 392
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000001851.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:23268477:23283346:-1 gene:ENSAMXG00000001817.2 transcript:ENSAMXT00000001851.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 120.939 bits (302), Expect = 2.140e-29 Identity = 114/423 (26.95%), Postives = 204/423 (48.23%), Query Frame = 2 Query: 125 AVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRV----------------PLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETE 1345 +VI+PT+W Y + +P ++ G L+AF+ + LL PLFG ++ K +++ +N I+GN +YF+ W++L R +AG G G +++ + R T ++R+ ++ RQ GL+IGPA + ++ ++G ++ + PG+ + LW ++VLL+Y S+ D+ PL+ P EL S+ + G SP+ E+ ++ +L+ ++ L F + F+ LE+++ P+ ++F + E+E S +Y CGV VI +V +R +S R V +R +L GLIL IS +W I L+ P ++ +IG+ VLG PF SL++K Q +Q + R + +A ++GP G + + Sbjct: 6 SVILPTIWRYLQTLDAPP---YFLGLGLSAFSFSGLLSGPLFGLISDKTRTTKKIILFANCFEIVGNFMYFMGYSKWLLLSSRLVAGIGTGAGSSIFSFLTRNTVPEDRSTVFAAVMACRQAGLLIGPAFNIFLRLCDFQLGPFIVNKFTAPGIFMCGLWLLLQLVVLLMYWDFPEPASRGSREDKQQQEDGEDEEDENDEVRPLVHP--HELTGSYGTVSIPPPRIPTVANGNLPRRSPSPPEQ--------SHSKFLREEVVVLLTAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFVFVRWLSRR-VAERVVLAIGLILCNISCVWCLIFLA-----NPQGALAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGVRRSIGGLATILGPLWAGGLTSN 409
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:103022629]) HSP 1 Score: 58.9214 bits (141), Expect = 6.900e-9 Identity = 53/190 (27.89%), Postives = 94/190 (49.47%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLM-----KDIKMKIGQVSIDIYNGPGLLLAVL 601 +S++K + F FL+ + ++I ++W Y K+ + AS + GW +AA+++ ++ PLFG + R + LV S + NI +Y I S+ + +LL R G GAG + + + TSL+ERT + + + G I+GPA + K + ++ +++Y P LL AV Sbjct: 26 RSRWKSIRVMYFTMFLSSVGFTIVITSIWPYLQKIDDTADAS-FLGWVVAAYSLGQMVASPLFGLWSNHRPR-REPLVCSIFFNVSANIYYAYVYLIPSYNKYHMLLARAFVGFGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAALSFIGEKGYTLHFLELKLNMYTAPALLAAVF 213
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:103022629]) HSP 1 Score: 49.2914 bits (116), Expect = 6.900e-6 Identity = 50/190 (26.32%), Postives = 89/190 (46.84%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLM-----KDIKMKIGQVSIDIYNGPGLLLAVL 601 +S++K + F FL+ + + I PT+ + + + GW +AA+++ ++ PLFG + R + LV S + NI +Y I S+ + +LL R G GAG + + + TSL+ERT + + + G I+GPA + K + ++ +++Y P LL AV Sbjct: 14 RSRWKSIRVMYFTMFLSSVGKIFIHPTI---NHNTIDDTADASFLGWVVAAYSLGQMVASPLFGLWSNHRPR-REPLVCSIFFNVSANIYYAYVYLIPSYNKYHMLLARAFVGFGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAALSFIGEKGYTLHFLELKLNMYTAPALLAAVF 199
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:564342]) HSP 1 Score: 54.299 bits (129), Expect = 2.057e-8 Identity = 41/142 (28.87%), Postives = 73/142 (51.41%), Query Frame = 2 Query: 104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTL-LVISNQLGIIGNIIYFIAS--HP---WMVLLGR-FLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP 508 FL+ + ++++ ++W + KV PS++ + GW LA++++A L P G A+ R ++ L+ S LG G+++Y A H ++VL R FL + + A T++ ERTP + L + G I+GP Sbjct: 19 FLSSVGFSIVMSSIWPFLQKV-DPSSSPTFLGWVLASYSLAQLFACPALG--AWANARGSSMPLLTSMLLGTAGHVMYMYAHAVHSRGRFLVLAARIFLGLGAGTTQAVVRAFASAATNMDERTPVMANLSACQALGFILGP 157
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO49760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFQ2]) HSP 1 Score: 145.591 bits (366), Expect = 3.131e-38 Identity = 129/434 (29.72%), Postives = 205/434 (47.24%), Query Frame = 2 Query: 107 LTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRK---------SYCSD---IIDAQLKQGIEELPSPTTME-------RISNFFNPIN-----YKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336 G+E AVI+PT+WLY S+ F S +YG AAF+ + L+ PLFG K ++ +N + GN +YFIA + +L GR +AG GAG ++A I R T+ +ERT + RQFGL+IGP + +K+ K+G +D Y PGL +A +W IL++ +Y L S QN D+ P+ T H S+ D I+ K + E+ S + R S+ + I K+ ++ I+ L F +F+ E++ P+++ W E+E S Y + IL +V++ +S R + DR L++ G+I ++ +W I L+ + + ++IV G V G PF + SL +K Q Q R VA+++GP GGS+ Sbjct: 21 FAGMEYAVILPTMWLYASERFQAE--SWFYGIIFAAFSFSSLIMSPLFGMWVDYTRNTKACILFANLFEMGGNFLYFIAWSKYWILGGRLVAGIGAGVSSAIFAQIARTTTEEERTSVYSIAMGLRQFGLLIGPGMNVFLKECNFKLGPFKVDHYTSPGLFMAAIWLLQEILMIFMYYDLPSVNQN----DKEPVFTEKPQITNGLHANKEGITNGGLSHLPDNIGSINTAAKDNLCEISSLNNSDSATVHKRRSSSVSSHIVDTWRLSKELMREEIIIILASQFIMFFNETAFEALFTPLSNHLLGWKELENSVAYCLIALEAILTFVLVSKVSKR-LSDRWLMVIGVIFEGLALVWYLIMLADSKPYEAKILPTVIV-GTLIIVFGLPFFSVANISLLSKLTDDKVQGVVQGFQRSSTGVAMILGPMWGGSL 446
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000008970.2 (major facilitator superfamily domain-containing protein 8 [Source:NCBI gene;Acc:101156398]) HSP 1 Score: 141.354 bits (355), Expect = 2.294e-36 Identity = 124/440 (28.18%), Postives = 215/440 (48.86%), Query Frame = 2 Query: 107 LTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY------PRLKSDRQNLSKSDR----------------VPLLTPMSMELEDSHRKSYCSDIIDAQLK-QGIEELP--SPTT---MERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336 L+G+E AVI+PT+W Y + + ++ G TL+AF+++ LL PLFG+L+ K +++ +N IIGN++YF+ W++L R +AG G G ++ + R T+ ++R ++ RQ GL+IGPA + ++ +G ++ Y PGL + +LW ++V+ +Y R K+ + K + PL+T S EL S+ D + I P SP T E +++ + Y+++L+ ++ L F + F+ LE+++ P+ +YF + E+E S +Y GV VI ++ +R + S+ V +R +L GL + IS +W CL + K L +IG+ VLG PF SL++K Q +Q + R V +A ++GP G + Sbjct: 20 LSGVEYAVILPTIWRYLQTL---NAEPYFLGLTLSAFSLSGLLSGPLFGHLSDRTQTTKKIILFANFFEIIGNLMYFMGYSKWLLLSSRLVAGIGTGAGSSIFGFLTRSTASEDRATVFAAVMACRQAGLLIGPAFNIFLRLCNFHLGSFVVNKYTAPGLFMCLLWILLQLVVVFMYWDLPYLERRKTKDSVIHKEEENTHASVEDEEEGDEEVKPLMT--SQELVGSYGSVVAPDPCRKHSRVSSIHNSPISSPVTSQSHEHVTSLKSSSLYREFLREEVVVLLAAQFITLFNQTALETMVTPLTQKYFNFGELENSVMYCLGGVVVIAGFLFVRWL-SKHVAERVVLAIGLTICNISCIW---CLIFLAKPLGGFSWQLTEFIIGVFLQVLGLPFVAVAQVSLFSKITSEKTQGFSQGVRRSVGGLATILGPLWAGGL 450
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: si:ch211-38m6.6 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:105356178]) HSP 1 Score: 132.109 bits (331), Expect = 4.250e-33 Identity = 123/448 (27.46%), Postives = 214/448 (47.77%), Query Frame = 2 Query: 107 LTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY---PRLKSDRQNLS---KSDRVPLLTPM---SMELEDSHRKSYCSDIIDAQL--KQGI---------------EELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLF--ISLIVIGIGFHVLGQPF-------CISCSESLYTKQVFVGDQDR---AQSILRMVINVALLIGPFVGGSM 1336 L+G+E AVI+PT+W Y + +P ++ G L+AF+++ LL PLFG+ + K++++ SN I GN +YF+ W++L R +AG GAG ++ + R T +ER ++ RQ GL+IGPA L ++ K+G +++ Y PG+ + +LW +VL +Y P +KS+ + L K + P+ +L ++R L K+ I ++ +P + R+ ++L+ ++ L F + F+ LE+++ PM RYF + E+ S +Y CGV VIL + +R +S + V DR +L GL++ + +W CL + + ++ +IG+ +LG PF C S + K V DR +Q + R V +A ++GP G + Sbjct: 29 LSGIEYAVILPTIWRYLQILEAPP---YFLGLGLSAFSLSGLLTGPLFGFWSDRSKTTKSIILFSNLFEIAGNFMYFLGYSKWLLLCSRLVAGIGAGAGSSIFGFLTRSTLPEERAGIFAAVMACRQAGLLIGPAFNLFLRLCDFKLGPFAVNKYTSPGIFMCLLWLLLQFVVLALYWDVPPIKSEEEGLRMEMKQEDEEEEAPLIRGDEQLAHTYRAVNLDHCYQTSLFIKKSIFLMHFHCFFKTDVLQKDFVTPVKV-RVKRSLGLSVCAEFLREEVVVVLTAQFITLFNQTALETMVTPMTQRYFSFGELGNSLMYSLCGVEVILGFFFVRWLSGK-VADRAVLAGGLVICCFACVW---CLVFLCNPRGGYGWELTAFIIGVFLQLLGLPFVAVSATDCCSVCMMVTKKNV---KTDRLWFSQGVRRSVGGLATILGPLWAGGL 465
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:101161364]) HSP 1 Score: 57.7658 bits (138), Expect = 1.473e-8 Identity = 61/225 (27.11%), Postives = 110/225 (48.89%), Query Frame = 2 Query: 62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHP-----WMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLM-----KDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQ-------NLSKSDRV 685 +S+++ + F FL+ + ++I +LW Y KV S + AS + GW +AA+++ ++ PLFG+ + R + LV S + + NI Y A P + +L+ R G GAG + + + TSL+ERT + + + G I+GPA + + I + + ++ + +Y P LL A+ + +LV+L+ + D N + DRV Sbjct: 28 RSRWRSIRVMYFTMFLSSVGFTIVITSLWPYLEKVDSGADAS-FLGWMVAAYSLGQMVASPLFGWWSNHRPR-REPLVCSIFINLAANIYYAYAYLPKTNNKYHLLMSRAFVGFGAGNVAVVRSYVAGATSLRERTGAMANMSACQALGFILGPALQAGLTFIGEEGITVDVIKLQLSMYTTPALLAALFGLINILLVVLVLKEHRVDEDGKQIQAINYTSEDRV 250
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000022267.1 (SMESG000022267.1) HSP 1 Score: 733.406 bits (1892), Expect = 0.000e+0 Identity = 403/410 (98.29%), Postives = 406/410 (99.02%), Query Frame = 2 Query: 32 MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQ 1261 MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLAGAGAGCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKYSILSNLFIIFSSYFSLMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRTLLLSGLILLTISYLWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYT + +G + Sbjct: 1 MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLAGAGAGCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKYSILSNLFIIFSSYFSLMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRTLLLSGLILLTISYLWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTNKFLLGTK 410
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000066500.1 (SMESG000066500.1) HSP 1 Score: 348.591 bits (893), Expect = 2.598e-115 Identity = 216/445 (48.54%), Postives = 293/445 (65.84%), Query Frame = 2 Query: 41 NCWNYVGK--SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIID--AQLKQGIEELPSPTTMERISNFFNPIN-YKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360 C N + K KF I A WGFLTG+ERA+I+PTLWLYF F AS YY TLAAFN+++ L PL+G+LA+ G R K LLVISNQL ++GNIIYF+AS PWMV++GRF+AG G+G EVPLYAD+VRVT+ +ERT YIV LLL RQ GLIIGPA TL++ IK +IG VS++IYN PG L+A+LW TI VL+ YP + L S + + M + K Y ++ D + L I + I N I+ + Y Y+ LS L I+FSSYF+L+ LE+VLPP+ RYF W E+ S+VYL G VI++Y IL+ + SR V+DR++LL+GLI L ISY+W++I L +I+ + L+ISL+ GI FH+ G I+C+ESL+TK + + D AQ++LR IN +LL+GP++ GS++ +VF Sbjct: 27 KCENKLNKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQAASSYYAATLAAFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNPEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMII------HKIYEKNMSDTSSHLNTEIRRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSV-SRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPYLVF 464
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000075932.1 (SMESG000075932.1) HSP 1 Score: 323.553 bits (828), Expect = 1.453e-105 Identity = 198/432 (45.83%), Postives = 278/432 (64.35%), Query Frame = 2 Query: 74 KICFI--AAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDS-HRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360 K+C I AA GFL G+ER++I+P+LWLYF F A YYG TL+AFN+++ + P +GYLA G R K LL+ISNQL IIGNIIYFIAS PWM+L GRF+ G GAG EVPLYAD+VRVT+++ERT YI+ LLL RQ GLIIGPA TL++ +K ++G ++++IYN PG ++ +LW TI++L+IYP + D + T ++M LE +K + + + E S T ++ FN K Y ++ L I F SYF L+ LES++PP+ RYF+W+E+ S++YL G+ VI+ ++L+ +S+ V D+ + GL+LL SYL LS L I+ Q NL ISL+ IGI H+ G I+C ESLYTK + + + D QS+LR VIN +LL+GP+V GS++ S +VF Sbjct: 44 KLCIIGSAASVGFLNGVERSIILPSLWLYFITKFGNEAAERYYGGTLSAFNLSVFVIAPFYGYLAQKGFRTKFLLIISNQLEIIGNIIYFIASEPWMILFGRFVCGIGAGSEVPLYADVVRVTNVKERTSYIIILLLSRQIGLIIGPAVTLILHPVKFQVGNITLNIYNSPGFIMGILWAIQTIVILIIYPEISKDGSEIDN-------TRINMRLEQRIFKKVFDGESSKTVTNEDSVEYNSITFNGKVKEIFNK--SKQYTNLVTVTLLCITFVSYFCLISLESIIPPITVRYFKWSEVHNSYLYLLAGILVIVTLLLLQKVSNY-VTDQKSYVCGLLLLICSYLILSFTLLFIESNQQNLSISLMGIGILLHIFGLSIVIACGESLYTKTLPISEMDLGQSVLRTVINFSLLVGPYVAGSLQFYSFIVF 465 The following BLAST results are available for this feature:
BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 4
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 3
BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035820 ID=SMED30035820|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1459bpback to top protein sequence of SMED30035820-orf-1 >SMED30035820-orf-1 ID=SMED30035820-orf-1|Name=SMED30035820-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=473bp MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTback to top Annotated Terms
The following terms have been associated with this transcript:
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