MFS domain-containing protein

Overview
NameMFS domain-containing protein
Smed IDSMED30035820
Length (bp)1459
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of MFS domain-containing protein (SMED30035820) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for MFS domain-containing protein (SMED30035820) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30035820

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
nervous systemSMED30035820h1SMcG0006458 dd_Smed_v4_16240_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035820h1SMcG0006458 dd_Smed_v4_16240_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30035820h1SMcG0006458 dd_Smed_v4_16240_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 58.151 bits (139), Expect = 7.686e-9
Identity = 49/176 (27.84%), Postives = 91/176 (51.70%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYN 574
            KS+++   I     FL+ +  +V++ ++W Y  K+  P+  + + GW +A++++  ++  P+FG  +    R K  L++S  + +  N +Y      ASH  + +L+ R L G GAG    + +     TSLQERT  +  + + +  G I+GPA T   +  +  I QV++   N
Sbjct:   33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPASTDEAQVPQGNIDQVAVVAIN 206          
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 58.151 bits (139), Expect = 7.686e-9
Identity = 49/176 (27.84%), Postives = 91/176 (51.70%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYN 574
            KS+++   I     FL+ +  +V++ ++W Y  K+  P+  + + GW +A++++  ++  P+FG  +    R K  L++S  + +  N +Y      ASH  + +L+ R L G GAG    + +     TSLQERT  +  + + +  G I+GPA T   +  +  I QV++   N
Sbjct:   33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPASTDEAQVPQGNIDQVAVVAIN 206          
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 56.9954 bits (136), Expect = 1.530e-8
Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS+++   I     FL+ +  +V++ ++W Y  K+  P+  + + GW +A++++  ++  P+FG  +    R K  L++S  + +  N +Y      ASH  + +L+ R L G GAG    + +     TSLQERT  +  + + +  G I+GP    C   +  K +   + ++ I++Y  P LL A
Sbjct:   33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218          
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 56.9954 bits (136), Expect = 1.541e-8
Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS+++   I     FL+ +  +V++ ++W Y  K+  P+  + + GW +A++++  ++  P+FG  +    R K  L++S  + +  N +Y      ASH  + +L+ R L G GAG    + +     TSLQERT  +  + + +  G I+GP    C   +  K +   + ++ I++Y  P LL A
Sbjct:   33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218          
BLAST of MFS domain-containing protein vs. Ensembl Human
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:HGNC Symbol;Acc:HGNC:28486])

HSP 1 Score: 56.9954 bits (136), Expect = 1.541e-8
Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS+++   I     FL+ +  +V++ ++W Y  K+  P+  + + GW +A++++  ++  P+FG  +    R K  L++S  + +  N +Y      ASH  + +L+ R L G GAG    + +     TSLQERT  +  + + +  G I+GP    C   +  K +   + ++ I++Y  P LL A
Sbjct:   33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218          
BLAST of MFS domain-containing protein vs. Ensembl Celegans
Match: Y53G8AR.7 (pep chromosome:WBcel235:III:3282308:3290215:1 gene:WBGene00021814.1 transcript:Y53G8AR.7a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y53G8AR.7)

HSP 1 Score: 59.3066 bits (142), Expect = 3.391e-9
Identity = 55/228 (24.12%), Postives = 101/228 (44.30%), Query Frame = 2
Query:  101 GFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIY-FIASHP-----WMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDI---KMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIID 757
            G   G++ ++  PTLW + + V  P+ ++ ++G+  AAF+V   L  P+FGY       V+  LV    + I+ NII+ F+ +       W++++ RF  G GAG    + A     +SL++R   I  +      G+ +GP   +    I    +  G   +D+Y  P    +++     + V+ I+  L+ +   L +            + EDS+      D I 
Sbjct:   55 GMFCGIQFSIFFPTLWPFLNTV-DPTASASFFGFITAAFSVGQGLASPVFGYWMNKAKSVRQPLVFGISVMILSNIIFCFVEAFAEKERRWVMMVARFFIGVGAGTIGVMRAYAATASSLKDRARAITFIQASYVIGMTLGPGIQVAFTPIGYPGLSKGVFHVDMYTSPAWFASII---SLLSVIFIFIFLEENYAGLDQ----------GADTEDSYTAMPTFDTIS 268          
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 144.05 bits (362), Expect = 2.657e-37
Identity = 132/441 (29.93%), Postives = 221/441 (50.11%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFL-TGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY---PRLKS--DRQNLSKSDRVPLLTPMSMELEDSHR----KSYCS---DIIDAQLKQGIEELPSPTTMERISN-FFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336
            + K K+ FI     FL +G+E AVI+PT+W Y   + +P    ++ G  L+AF+ + L+  P+FG+ +      KT+++ SN   I+GN +YF+    W++L  R +AG GAG    ++  + R T   ER      ++  RQ GL+IGPA  + ++    K+G   ++ Y  PGL +  +W      V+ +Y   P L S  ++Q   +  R     P+ M LED  R     SY S   +  + QL   I   P  +     S+ F N    +++L+  ++  L   F + F+   LE+++ P+  +YF + E+  S +Y  CGV VI  + ++R + SR +EDR +L  GL++ + + +W   CL  +   Q  L   L   +IG+   +LG PF      SL++K      Q  +Q + R V  +A ++GP   G +
Sbjct:    4 RQKRKLSFITIGLTFLLSGIEYAVILPTIWRYLQLLEAPP---YFLGLGLSAFSFSGLVTGPVFGHWSDKTRTTKTIILFSNVFEIVGNFMYFMGYSKWLLLSSRLVAGIGAGAGSSIFGFLTRTTLPDERARVFAAVMACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGLFMCGMWLLMQFAVMGLYWDIPPLDSFAEQQMPLREVRGEEDEPL-MSLEDDDRTAVADSYGSLNPEQTETQLSSQIPPSPPESPPPDTSDPFENFSASREFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWL-SRVLEDRVVLAVGLLICSGACVW---CLIFLANPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 436          
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01045212.1 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:564731])

HSP 1 Score: 129.413 bits (324), Expect = 3.819e-32
Identity = 113/416 (27.16%), Postives = 198/416 (47.60%), Query Frame = 2
Query:  125 AVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVP-------LLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETE 1345
            AVI+PT+W Y   +   + A ++ G +L+AF+ + LL  PLFG+ +   +  K +++ +N   I+GN +YF+    W++L  R +AG G G    ++  + R T+ ++R+     ++  RQ GL+IGP   L ++    ++G   ++ Y  PGL + +LW    ++V+ +Y  +  + +   +S R P            +  L   +  S     ID         +     +      F      ++L+  ++  L   F + F+   LE+++ P+  ++F + E+E S +Y  CGV VI  ++ +R  S R  E R +L  GLIL  IS +W   CL  +   Q      L   +IG+   VLG PF      SL++K      Q  +Q I R V  +A ++GP   G + + 
Sbjct:   35 AVILPTIWRYLQTL---NAAPYFLGLSLSAFSFSGLLAGPLFGHWSDRTLTTKKIILFANIFEIVGNFMYFMGFSKWLLLSSRLVAGIGTGAGSSIFGFLTRNTAPEDRSTVFAAVMACRQAGLLIGPGFNLFLRLCDFEMGPFIVNKYTAPGLFMCLLWILLQLVVVFMYWDISPEDER--RSQRSPEQEEEEEEEEEEAKPLVGPNELSGSYGTIDLMCVCVCVCVCVCVCVCVCVCVF---LLSEFLREEVVVLLAAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFLFVRWFSKRAAE-RVVLAVGLILCNISCVW---CLIFLANPQGGFAWQLAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGIRRSVGGLATILGPLWAGGLTSN 438          
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: CABZ01045212.1 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:564731])

HSP 1 Score: 93.9745 bits (232), Expect = 3.287e-20
Identity = 56/193 (29.02%), Postives = 106/193 (54.92%), Query Frame = 2
Query:  110 TGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVP 688
            T L  +VI+PT+W Y   +   + A ++ G +L+AF+ + LL  PLFG+ +   +  K +++ +N   I+GN +YF+    W++L  R +AG G G    ++  + R T+ ++R+     ++  RQ GL+IGP   L ++    ++G   ++ Y  PGL + +LW    ++V+ +Y  +  + +   +S R P
Sbjct:    1 TLLSISVILPTIWRYLQTL---NAAPYFLGLSLSAFSFSGLLAGPLFGHWSDRTLTTKKIILFANIFEIVGNFMYFMGFSKWLLLSSRLVAGIGTGAGSSIFGFLTRNTAPEDRSTVFAAVMACRQAGLLIGPGFNLFLRLCDFEMGPFIVNKYTAPGLFMCLLWILLQLVVVFMYWDISPEDER--RSQRSP 188          

HSP 2 Score: 59.6918 bits (143), Expect = 3.801e-9
Identity = 49/147 (33.33%), Postives = 74/147 (50.34%), Query Frame = 2
Query:  911 GLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETE 1345
             LE+++ P+  ++F + E+E S +Y  CGV VI  ++ +R  S R  E R +L  GLIL  IS +W   CL  +   Q      L   +IG+   VLG PF      SL++K      Q  +Q I R V  +A ++GP   G + + 
Sbjct:  264 ALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFLFVRWFSKRAAE-RVVLAVGLILCNISCVW---CLIFLANPQGGFAWQLAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGIRRSVGGLATILGPLWAGGLTSN 406          
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 83.1889 bits (204), Expect = 4.472e-17
Identity = 87/300 (29.00%), Postives = 145/300 (48.33%), Query Frame = 2
Query:  482 RQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY---PRLKS--DRQNLSKSDRVPLLTPMSMELEDSHR----KSYCS---DIIDAQLKQGIEELPSPTTMERISN-FFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336
            RQ GL+IGPA  + ++    K+G   ++ Y  PGL +  +W      V+ +Y   P L S  ++Q   +  R     P+ M LED  R     SY S   +  + QL   I   P  +     S+ F N    +++L+  ++  L   F + F+   LE+++ P+  +YF + E+  S +Y  CGV VI  + ++R + SR +EDR +L  GL++ + + +W   CL  +   Q  L   L   +IG+   +LG PF      SL++K      Q  +Q + R V  +A ++GP   G +
Sbjct:    4 RQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGLFMCGMWLLMQFAVMGLYWDIPPLDSFAEQQMPLREVRGEEDEPL-MSLEDDDRTAVADSYGSLNPEQTETQLSSQIPPSPPESPPPDTSDPFENFSASREFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIAGFFLVRWL-SRVLEDRVVLAVGLLICSGACVW---CLIFLANPQGGLGFELFEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 298          
BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:564342])

HSP 1 Score: 63.1586 bits (152), Expect = 3.494e-10
Identity = 60/248 (24.19%), Postives = 118/248 (47.58%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASHPWM-VLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMK-----DIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQ-------NLSKSDRVPLLTPMSMELEDSHRKSYCSDII 754
            +S+++   +  F  FL+ +   ++I ++W Y  K+   + AS + GW +AA+++  ++  P FG  +    R +  LV S  + +  NI    +Y   SH  + +LL R   G GAG    + + +   TSL+ERT  +  +   +  G I+GPA   ++       + + + ++ +++Y  P LL A     + +LV+L+      D         N +  +RV +  P  +E +  H   + S+++
Sbjct:   25 RSRWRSIRVMYFTMFLSSVGFTIVITSIWPYLKKIDESADAS-FLGWVVAAYSLGQMVASPFFGLWSNHRPR-REPLVCSIFINVSANIYYSYVYLPPSHNQIHMLLARTFVGIGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAVLSFIGETGVSVDVIKLQVNMYTAPALLAACFGVINILLVILVLREHSVDDHGNRIRPINYTPEERVDV--PPEVEGDIDHIAVFTSNVL 268          
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683])

HSP 1 Score: 140.584 bits (353), Expect = 8.614e-36
Identity = 116/432 (26.85%), Postives = 210/432 (48.61%), Query Frame = 2
Query:   86 IAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSH------RKSYCSDIIDAQLKQGIEELPSPTTMERISNFF-----------NPINYK--DYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPN--LFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGP 1318
            +  F   L G+E AVI+PT+W+Y   + +      + G  L+A +   LL  PLFGY +    + K ++++SN   I GN++YF+    W +L  R +AG G+G    ++  + R +S +ER   +   +  RQ GL+IGPA  + ++    +IG   +D ++ PG+ +  LW     LVL ++  +K   Q     ++ PLL       E  +        ++ +D +        + L S ++ME I +               +N +    L+  ++  L   F   F+   LE+++ P+A  Y  + +++ S +Y  CG+ +++ ++++R +  R   DR LL+ GL +  IS +W   CL  + K + +  L ++  V+G+   VLG PF  +C  SL++K      Q     + R V  +A ++GP
Sbjct:   30 VIGFIFLLNGIEYAVILPTIWMYLQSLDAEPV---FLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEPEDLGKKSLNDRLSGLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRAL-GRCTSDRLLLIFGLFVCNISCIW---CLVFMAKPRGSYGLLLAEFVVGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGP 454          
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683])

HSP 1 Score: 140.198 bits (352), Expect = 8.708e-36
Identity = 117/432 (27.08%), Postives = 209/432 (48.38%), Query Frame = 2
Query:   86 IAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSH------RKSYCSDIIDAQLKQGIEELPSPTTMERISNFF-----------NPINYK--DYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPN--LFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGP 1318
            +  F   L G+E AVI+PT+W+Y     S      + G  L+A +   LL  PLFGY +    + K ++++SN   I GN++YF+    W +L  R +AG G+G    ++  + R +S +ER   +   +  RQ GL+IGPA  + ++    +IG   +D ++ PG+ +  LW     LVL ++  +K   Q     ++ PLL       E  +        ++ +D +        + L S ++ME I +               +N +    L+  ++  L   F   F+   LE+++ P+A  Y  + +++ S +Y  CG+ +++ ++++R +  R   DR LL+ GL +  IS +W   CL  + K + +  L ++  V+G+   VLG PF  +C  SL++K      Q     + R V  +A ++GP
Sbjct:   21 VIGFIFLLNGIEYAVILPTIWMYLQ---SLDAEPVFLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEPEDLGKKSLNDRLSGLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRAL-GRCTSDRLLLIFGLFVCNISCIW---CLVFMAKPRGSYGLLLAEFVVGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGP 445          
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: dnajc18 (DnaJ heat shock protein family (Hsp40) member C18 [Source:Xenbase;Acc:XB-GENE-5795683])

HSP 1 Score: 137.502 bits (345), Expect = 5.904e-35
Identity = 112/421 (26.60%), Postives = 205/421 (48.69%), Query Frame = 2
Query:  125 AVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSH------RKSYCSDIIDAQLKQGIEELPSPTTMERI---------------SNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPN--LFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGP 1318
            AVI+PT+W+Y   + +      + G  L+A +   LL  PLFGY +    + K ++++SN   I GN++YF+    W +L  R +AG G+G    ++  + R +S +ER   +   +  RQ GL+IGPA  + ++    +IG   +D ++ PG+ +  LW     LVL ++  +K   Q     ++ PLL       E  +        ++ +D +        + L S ++ME I                +  + ++ K  L+  ++  L   F   F+   LE+++ P+A  Y  + +++ S +Y  CG+ +++ ++++R +  R   DR LL+ GL +  IS +W   CL  + K + +  L ++  V+G+   VLG PF  +C  SL++K      Q     + R V  +A ++GP
Sbjct:   26 AVILPTIWMYLQSLDAEPV---FLGLVLSALSFTELLVGPLFGYWSDRTGQTKRVIILSNFFEIAGNLMYFVGISKWFLLGSRLVAGVGSGAGASIFGYLTRFSSNKERLSVLALAMACRQVGLLIGPAFNVFLRYCNFQIGPFHVDKFSAPGIFMCALWTLMQPLVLFMFYDIKLTPQKPHDEEQDPLLYQGDTGNEGCNNVYGTINHNHITDHVAFSSSMDDKALTSSSSMEDIHSTITKDPEPEDLGKKSLNDRLSGKRLLREEVVVLLTAQFVMLFNQTALETLVTPLAQTYLGFQDLQNSLLYFLCGIEMLIGFLVVRAL-GRCTSDRLLLIFGLFVCNISCIW---CLVFMAKPRGSYGLLLAEFVVGVFLQVLGLPFVSACQVSLFSKVTAKNTQGFNHGLRRSVGGLATILGP 439          
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:100495784])

HSP 1 Score: 60.4622 bits (145), Expect = 3.457e-9
Identity = 53/194 (27.32%), Postives = 101/194 (52.06%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTL---LMKDIKMKIGQV--SIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSD 655
            FL+ +  ++++ ++W Y  KV   + AS + GW +A+F++  ++  PLFG  +    R +  LV+S  + +  + +Y      ASH  + +LL R L G G+G    + + +   TSL ERT  +  +  F+  G I+GPA      ++ +  + IG +   +++Y  P L+ A+L   + IL+  ++   + D
Sbjct:   45 FLSSVGFSIVMTSIWPYLQKVDQSADAS-FLGWVIASFSLGQMVASPLFGLWSNHRPR-REPLVVSITILVAASCLYAYVQVPASHNKYYMLLARTLVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAIGFILGPAFQAGLSMIGENGVTIGAIYLQVNMYTAPALMGALLGIGNIILIFAVFREHRVD 236          
BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Match: MFSD8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:100495784])

HSP 1 Score: 60.077 bits (144), Expect = 4.792e-9
Identity = 53/194 (27.32%), Postives = 101/194 (52.06%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTL---LMKDIKMKIGQV--SIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSD 655
            FL+ +  ++++ ++W Y  KV   + AS + GW +A+F++  ++  PLFG  +    R +  LV+S  + +  + +Y      ASH  + +LL R L G G+G    + + +   TSL ERT  +  +  F+  G I+GPA      ++ +  + IG +   +++Y  P L+ A+L   + IL+  ++   + D
Sbjct:   45 FLSSVGFSIVMTSIWPYLQKVDQSADAS-FLGWVIASFSLGQMVASPLFGLWSNHRPR-REPLVVSITILVAASCLYAYVQVPASHNKYYMLLARTLVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAIGFILGPAFQAGLSMIGENGVTIGAIYLQVNMYTAPALMGALLGIGNIILIFAVFREHRVD 236          
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425])

HSP 1 Score: 60.077 bits (144), Expect = 3.400e-9
Identity = 54/188 (28.72%), Postives = 95/188 (50.53%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS++K   I     FL+ +  +++I ++W Y  K+   + AS + GW +A++++  ++  PLFG  +    R K  L++S  + +  N +Y       A + + +L+ R L G GAG    + + I   TSLQERT  +      +  G I+GP    C  L+  K +   I ++ +++Y  P LL A
Sbjct:   34 KSRWKSVRILYLTMFLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 219          
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425])

HSP 1 Score: 60.077 bits (144), Expect = 3.400e-9
Identity = 54/188 (28.72%), Postives = 95/188 (50.53%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS++K   I     FL+ +  +++I ++W Y  K+   + AS + GW +A++++  ++  PLFG  +    R K  L++S  + +  N +Y       A + + +L+ R L G GAG    + + I   TSLQERT  +      +  G I+GP    C  L+  K +   I ++ +++Y  P LL A
Sbjct:   34 KSRWKSVRILYLTMFLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 219          
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425])

HSP 1 Score: 57.3806 bits (137), Expect = 3.430e-9
Identity = 50/174 (28.74%), Postives = 89/174 (51.15%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            FL+ +  +++I ++W Y  K+   + AS + GW +A++++  ++  PLFG  +    R K  L++S  + +  N +Y       A + + +L+ R L G GAG    + + I   TSLQERT  +      +  G I+GP    C  L+  K +   I ++ +++Y  P LL A
Sbjct:    2 FLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 173          
BLAST of MFS domain-containing protein vs. Ensembl Mouse
Match: Mfsd8 (major facilitator superfamily domain containing 8 [Source:MGI Symbol;Acc:MGI:1919425])

HSP 1 Score: 57.3806 bits (137), Expect = 3.430e-9
Identity = 50/174 (28.74%), Postives = 89/174 (51.15%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            FL+ +  +++I ++W Y  K+   + AS + GW +A++++  ++  PLFG  +    R K  L++S  + +  N +Y       A + + +L+ R L G GAG    + + I   TSLQERT  +      +  G I+GP    C  L+  K +   I ++ +++Y  P LL A
Sbjct:    2 FLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 173          
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q0VA82|MFSD8_DANRE (Major facilitator superfamily domain-containing protein 8 OS=Danio rerio OX=7955 GN=mfsd8 PE=2 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 2.638e-9
Identity = 60/248 (24.19%), Postives = 118/248 (47.58%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASHPWM-VLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMK-----DIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQ-------NLSKSDRVPLLTPMSMELEDSHRKSYCSDII 754
            +S+++   +  F  FL+ +   ++I ++W Y  K+   + AS + GW +AA+++  ++  P FG  +    R +  LV S  + +  NI    +Y   SH  + +LL R   G GAG    + + +   TSL+ERT  +  +   +  G I+GPA   ++       + + + ++ +++Y  P LL A     + +LV+L+      D         N +  +RV +  P  +E +  H   + S+++
Sbjct:   25 RSRWRSIRVMYFTMFLSSVGFTIVITSIWPYLKKIDESADAS-FLGWVVAAYSLGQMVASPFFGLWSNHRPR-REPLVCSIFINVSANIYYSYVYLPPSHNQIHMLLARTFVGIGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAVLSFIGETGVSVDVIKLQVNMYTAPALLAACFGVINILLVILVLREHSVDDHGNRIRPINYTPEERVDV--PPEVEGDIDHIAVFTSNVL 268          
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BH31|MFSD8_MOUSE (Major facilitator superfamily domain-containing protein 8 OS=Mus musculus OX=10090 GN=Mfsd8 PE=2 SV=1)

HSP 1 Score: 60.077 bits (144), Expect = 2.378e-8
Identity = 54/188 (28.72%), Postives = 95/188 (50.53%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYF-----IASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS++K   I     FL+ +  +++I ++W Y  K+   + AS + GW +A++++  ++  PLFG  +    R K  L++S  + +  N +Y       A + + +L+ R L G GAG    + + I   TSLQERT  +      +  G I+GP    C  L+  K +   I ++ +++Y  P LL A
Sbjct:   34 KSRWKSVRILYLTMFLSSVGFSIVIMSIWPYLQKIDQTADAS-FLGWVIASYSLGQMVASPLFGLWSNYRPR-KEPLIVSISISVAANCLYAYVHVPAAHNKYYMLIARGLVGFGAGNVAVVRSYIAGATSLQERTNAMANTSTCQALGFILGPVFQTCFALIGEKGVTWDIIKLQVNMYTAPVLLAA 219          
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6GPQ3|MFSD8_XENLA (Major facilitator superfamily domain-containing protein 8 OS=Xenopus laevis OX=8355 GN=mfsd8 PE=2 SV=1)

HSP 1 Score: 59.3066 bits (142), Expect = 4.486e-8
Identity = 55/202 (27.23%), Postives = 104/202 (51.49%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLMKDIKMKIGQVS--IDIYNGPGLLLAVLWGFHTILVLLIYPRLKSD--RQNLSK 673
            FL+ +  ++++ ++W Y  KV   + AS + GW +A+F++  ++  PLFG  +    R +  LV+S  + +  + +Y      ASH  + +LL R   G G+G    + + +   TSL ERT  +  +  F+  G I+GP   A   ++ +  + I  +S  +++Y  P L+ A+L   + IL+  I+   + D   +N+S 
Sbjct:   45 FLSSVGFSIVMTSIWPYLQKVDQSADAS-FLGWVIASFSLGQMVASPLFGLWSNHRPR-REPLVVSITILVAASCLYAYVHVPASHNKYYMLLARTFVGFGSGNVAVVRSYVAGATSLSERTGAMANISAFQAMGFILGPAFQAALSVIGETGITINGISLQVNMYTAPALMGALLGIGNIILIFAIFREHRVDDLEKNVSS 244          
BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8NHS3|MFSD8_HUMAN (Major facilitator superfamily domain-containing protein 8 OS=Homo sapiens OX=9606 GN=MFSD8 PE=1 SV=1)

HSP 1 Score: 56.225 bits (134), Expect = 4.446e-7
Identity = 51/188 (27.13%), Postives = 96/188 (51.06%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFI----ASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP---ACTLLM--KDIKMKIGQVSIDIYNGPGLLLA 595
            KS+++   I     FL+ +  +V++ ++W Y  K+  P+  + + GW +A++++  ++  P+FG  +    R K  L++S  + +  N +Y      ASH  + +L+ R L G GAG    + +     TSLQERT  +  + + +  G I+GP    C   +  K +   + ++ I++Y  P LL A
Sbjct:   33 KSRWRSIRILYLTMFLSSVGFSVVMMSIWPYLQKI-DPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPR-KEPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQERTSSMANISMCQALGFILGPVFQTCFTFLGEKGVTWDVIKLQINMYTTPVLLSA 218          
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A1I8HRG6 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 338.576 bits (867), Expect = 8.848e-108
Identity = 203/439 (46.24%), Postives = 281/439 (64.01%), Query Frame = 2
Query:   65 SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIG-VRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELP------SPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360
            +K ++  I + WG LTG+ERA+I+PTLWLYF   F  S A  +YG TLAAFN++ L+C PLFG+L+    VRVK LL+ +NQL I GN++YF+A  PW++ LGRF+AG GAG E PLYAD+VRVT+ +ERT  IV LLL RQFGLI GPA TLLM  ++ K+ +  ID+YN PGL +A+LW  HTI ++ IYP +   R      D V      S +      +S   D +     Q  E  P           E   + F+    K YLK    + LF+ FSSYF+LM LE+VLPP A+RYF W E  TS VYLG G+ VI VY++++ +S++  EDR LLL+G+ +L  +Y W  + L  +++ +P L+I+L+++GI  HV+G PF  +  ESLYTK V VG+ D AQ + R VI +++L+GP +GGS++    +VF
Sbjct:   34 AKLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTISHSRFAGGNGDEV---AAESTDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAK-FEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGSLQFVPWLVF 468          
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267FNL8 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006869g2 PE=4 SV=1)

HSP 1 Score: 338.576 bits (867), Expect = 3.644e-107
Identity = 201/432 (46.53%), Postives = 278/432 (64.35%), Query Frame = 2
Query:   65 SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIG-VRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELP------SPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSME 1339
            +K ++  I + WG LTG+ERA+I+PTLWLYF   F  S A  +YG TLAAFN++ L+C PLFG+L+    VRVK LL+ +NQL I GN++YF+A  PW++ LGRF+AG GAG E PLYAD+VRVT+ +ERT  IV LLL RQFGLI GPA TLLM  ++ K+ +  ID+YN PGL +A+LW  HTI ++ IYP +   R      D V      S +      +S   D +     Q  E  P           E   + F+    K YLK    + LF+ FSSYF+LM LE+VLPP A+RYF W E  TS VYLG G+ VI VY++++ +S++  EDR LLL+G+ +L  +Y W  + L  +++ +P L+I+L+++GI  HV+G PF  +  ESLYTK V VG+ D AQ + R VI +++L+GP +GGS++
Sbjct:   40 AKLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTISHSRFAGGNGDEV---AAESTDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAK-FEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGSLQ 467          
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A267GD89 (MFS domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig006869g1 PE=4 SV=1)

HSP 1 Score: 336.265 bits (861), Expect = 2.380e-106
Identity = 200/431 (46.40%), Postives = 277/431 (64.27%), Query Frame = 2
Query:   65 SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIG-VRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELP-----SPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSME 1339
            +K ++  I + WG LTG+ERA+I+PTLWLYF   F  S A  +YG TLAAFN++ L+C PLFG+L+    VRVK LL+ +NQL I GN++YF+A  PW++ LGRF+AG GAG E PLYAD+VRVT+ +ERT  IV LLL RQFGLI GPA TLLM  ++ K+ +  ID+YN PGL +A+LW  HTI ++ IYP +   R      D V      S +      +S   D +     Q  E  P          E   + F+    K YLK    + LF+ FSSYF+LM LE+VLPP A+RYF W E  TS VYLG G+ VI VY++++ +S++  EDR LLL+G+ +L  +Y W  + L  +++ +P L+I+L+++GI  HV+G PF  +  ESLYTK V VG+ D AQ + R VI +++L+GP +GG ++
Sbjct:   40 AKLRVVLIGSTWGLLTGVERAIILPTLWLYFYNKFDMSAAVRFYGATLAAFNISALVCTPLFGWLSQRNYVRVKFLLIAANQLEIAGNLLYFVAPQPWLIFLGRFVAGVGAGAEPPLYADVVRVTTKKERTGVIVYLLLARQFGLIAGPALTLLMHPLRYKVKKFVIDVYNSPGLFMALLWAVHTIAIIAIYPTISHSRFAGGNGDEV---AAESTDTSQKPSRSASYDALHEASSQVAEAEPQQQQQQQQQQEDQPSCFSMDKMKLYLKIDTFAMLFVTFSSYFNLMALEAVLPPAANRYFGWDEFNTSLVYLGAGILVIFVYLVVKFLSAK-FEDRLLLLTGICILIGAYFWNFMALIFVERAKPTLYITLVLLGITGHVIGMPFTFALPESLYTKSVPVGEMDIAQGVFRSVIALSILVGPLIGGLLQ 466          
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A448XFL8 (Uncharacterized protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS28931 PE=4 SV=1)

HSP 1 Score: 328.561 bits (841), Expect = 4.255e-103
Identity = 197/441 (44.67%), Postives = 283/441 (64.17%), Query Frame = 2
Query:   56 VGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPR-------LKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEEL----PSPTTMERISNFFNP--INYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSME 1339
            VG  KF I F AA WGFLT +ER+VI+ TL+LYF   ++   A ++YG T++AF++AIL+  P+FG LA  G+RVK +L++S+QL I+GN++Y I + PW+VLLGRF++GAGA CE PLYADI RVTSL+ERTP IVT+L+ RQ GL+ GPA TL++ ++ + I   S+ +YNGPGLL+A LW  HT++VLL YP        + S    L+  D     +      + +   SY ++    QL    E+     PS  T    SN+      + + Y  Y++++   + F+ YF  M LE+VLPP+A+RYF W E+E S+VYLG G  V++   +L  + ++   DR+L+L+G   L +SY+WL++C + +     +  I L +IGI  HV G P   +CSESLY+K V V D +RAQ+ILR VINVA L+GPF GG++ 
Sbjct:   49 VGSPKFWISFSAATWGFLTSVERSVILSTLFLYFKTYWNAEAAQNFYGATMSAFSLAILIMTPVFGLLAHAGLRVKVILLLSDQLEIVGNLLYLIGTSPWLVLLGRFISGAGASCEPPLYADIARVTSLEERTPIIVTILVSRQCGLMFGPAFTLILHNMNVTIAGFSLSVYNGPGLLMAGLWILHTLVVLLTYPNIDDVGRVIDSSLNKLTSRDLQNCCSCYQTCPQAAGSSSY-NETGSLQLSDCAEDTHLIPPSDETTGGQSNYCRCGLASLRPYSAYNLVTMYAVSFAVYFCFMSLEAVLPPVANRYFDWNEVEVSYVYLGAGGLVLVFCAVLHFL-TQCCSDRSLVLAGCATLVVSYIWLAVCCATLTTAPLSTAIPLTMIGIAIHVAGMPLATACSESLYSKLVKVVDMNRAQAILRTVINVAFLLGPFFGGTLH 487          
BLAST of MFS domain-containing protein vs. TrEMBL
Match: A0A0X3PDP8 (Putative MFS-type transporter C330.07c OS=Schistocephalus solidus OX=70667 GN=YJ87 PE=4 SV=1)

HSP 1 Score: 318.931 bits (816), Expect = 9.725e-100
Identity = 192/440 (43.64%), Postives = 280/440 (63.64%), Query Frame = 2
Query:   41 NCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360
            N   +    K+ I FIA+ WGFLT +ERA+I+PT+WLYF   +    A  +YG TLAAF+++IL+  PLFGY     V V+ LL+ +N + +IGN+ Y +   PW V  GR +AG GA CE P+YAD+ R T   ERTPYI+ LLL RQ GLIIGPA TL+++ I ++IG V I +YNGPGL++AVLW  HT+L+   YP       +L KS  +         +E+       S  ++A LK   +  PS + ++        +++  Y +Y I++  F+IFS+YF +M LESVL P+A+R+F+W E+E S+VY+G  V VI+V  ++ L+ +R +EDR L+L GL  LT+SY +LS  L  +      L  +L+V+G+  HV+G PF ++ +ESLYTK +     D+AQ+ILR +INVA L+GP+VGGS++ +  +VF
Sbjct:   63 NVVRHKRPPKYAIAFIASTWGFLTNVERAIILPTMWLYFRDYWGDEVAKSFYGSTLAAFSLSILVTTPLFGYAGHANVNVRHLLMFANFMEVIGNVAYLLPYSPWFVFFGRLIAGVGASCESPMYADLTRTTEESERTPYIIILLLSRQVGLIIGPAFTLILRQITIEIGPVQISVYNGPGLVMAVLWVVHTMLIFFTYP-------HLDKSGEL---------VEELQSGEVASSPVEASLKHSRQ--PSDSRIQ--------VSFAGYGQYHIVTLYFVIFSAYFCVMSLESVLSPVANRFFKWNEVEVSYVYIGSSVLVIIVSGLMHLM-TRCMEDRALVLLGLFFLTVSYAFLSFVLHNVLTMTKTLGATLVVVGVAIHVIGMPFPLAITESLYTKFIPSHQLDKAQTILRTIINVAFLLGPYVGGSLQGKPTIVF 475          
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-38m6.6 (si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-179])

HSP 1 Score: 120.939 bits (302), Expect = 1.717e-29
Identity = 115/415 (27.71%), Postives = 199/415 (47.95%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPG--LLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336
            FL+G+E AVI+PT+W Y   + +P+   ++ G  L+AF+ + LL  PLFG  + +    K++++ SN   I+GN +YF+    W++L  R +AG GAG    ++  + R T   ER      ++  RQ GL+IGPA  + ++    K+G   ++ Y  PG   LL        + V +    + SD   + +   VPLL+                             L  P+    +  FF    + ++L+  ++  L   F + F+   LE+++ P+  +YF + E+  S +Y  CGV VI  + ++R + SR +EDR +L  GL++   + +W   C+  +   Q    + L   +IG+   +LG PF      SL++K      Q  +Q + R V  +A ++GP   G +
Sbjct:   19 FLSGVEYAVILPTIWKYLQILDAPA---YFLGLGLSAFSFSGLLSGPLFGRWSDVTRTTKSIILFSNVFEIVGNFMYFLGYSKWLLLASRLVAGIGAGAGSSIFGFLTRTTLPDERARVFAAVMACRQAGLLIGPAFNIFLRLCDFKLGPFIVNKYTSPGCVFLLCEKSVCVCVCVSVCVCVIYSDILFIDQCP-VPLLS-----------------------------LFPPSLYFSLVFFF----FSEFLREEVVVLLTAQFITLFNQTALETMVTPLTQKYFGFGELGNSVMYSLCGVEVIGGFFLVRWL-SRVLEDRAVLAVGLLICCGACVW---CIIFLASPQGGFAVELTEFIIGVFLQLLGLPFVAVSQVSLFSKVTAEKTQGFSQGVRRSVGGLATILGPLWAGGL 392          
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000001851.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:23268477:23283346:-1 gene:ENSAMXG00000001817.2 transcript:ENSAMXT00000001851.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 120.939 bits (302), Expect = 2.140e-29
Identity = 114/423 (26.95%), Postives = 204/423 (48.23%), Query Frame = 2
Query:  125 AVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRV----------------PLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETE 1345
            +VI+PT+W Y   + +P    ++ G  L+AF+ + LL  PLFG ++      K +++ +N   I+GN +YF+    W++L  R +AG G G    +++ + R T  ++R+     ++  RQ GL+IGPA  + ++    ++G   ++ +  PG+ +  LW    ++VLL+Y          S+ D+                 PL+ P   EL  S+            +  G     SP+  E+        ++  +L+  ++  L   F + F+   LE+++ P+  ++F + E+E S +Y  CGV VI  +V +R +S R V +R +L  GLIL  IS +W  I L+      P   ++  +IG+   VLG PF      SL++K      Q  +Q + R +  +A ++GP   G + + 
Sbjct:    6 SVILPTIWRYLQTLDAPP---YFLGLGLSAFSFSGLLSGPLFGLISDKTRTTKKIILFANCFEIVGNFMYFMGYSKWLLLSSRLVAGIGTGAGSSIFSFLTRNTVPEDRSTVFAAVMACRQAGLLIGPAFNIFLRLCDFQLGPFIVNKFTAPGIFMCGLWLLLQLVVLLMYWDFPEPASRGSREDKQQQEDGEDEEDENDEVRPLVHP--HELTGSYGTVSIPPPRIPTVANGNLPRRSPSPPEQ--------SHSKFLREEVVVLLTAQFITLFNQTALETMVTPLTQKFFNFGELENSIMYCVCGVEVIAGFVFVRWLSRR-VAERVVLAIGLILCNISCVWCLIFLA-----NPQGALAEFIIGVFLQVLGLPFVAVAQVSLFSKITAEKTQGFSQGVRRSIGGLATILGPLWAGGLTSN 409          
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:103022629])

HSP 1 Score: 58.9214 bits (141), Expect = 6.900e-9
Identity = 53/190 (27.89%), Postives = 94/190 (49.47%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLM-----KDIKMKIGQVSIDIYNGPGLLLAVL 601
            +S++K   +  F  FL+ +   ++I ++W Y  K+   + AS + GW +AA+++  ++  PLFG  +    R +  LV S    +  NI    +Y I S+  + +LL R   G GAG    + + +   TSL+ERT  +  +   +  G I+GPA    +     K   +   ++ +++Y  P LL AV 
Sbjct:   26 RSRWKSIRVMYFTMFLSSVGFTIVITSIWPYLQKIDDTADAS-FLGWVVAAYSLGQMVASPLFGLWSNHRPR-REPLVCSIFFNVSANIYYAYVYLIPSYNKYHMLLARAFVGFGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAALSFIGEKGYTLHFLELKLNMYTAPALLAAVF 213          
BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:103022629])

HSP 1 Score: 49.2914 bits (116), Expect = 6.900e-6
Identity = 50/190 (26.32%), Postives = 89/190 (46.84%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNI----IYFIASH-PWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLM-----KDIKMKIGQVSIDIYNGPGLLLAVL 601
            +S++K   +  F  FL+ + +  I PT+          +  + + GW +AA+++  ++  PLFG  +    R +  LV S    +  NI    +Y I S+  + +LL R   G GAG    + + +   TSL+ERT  +  +   +  G I+GPA    +     K   +   ++ +++Y  P LL AV 
Sbjct:   14 RSRWKSIRVMYFTMFLSSVGKIFIHPTI---NHNTIDDTADASFLGWVVAAYSLGQMVASPLFGLWSNHRPR-REPLVCSIFFNVSANIYYAYVYLIPSYNKYHMLLARAFVGFGAGNVAVVRSYVAGATSLKERTSAMANMSACQALGFILGPALQAALSFIGEKGYTLHFLELKLNMYTAPALLAAVF 199          
BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:564342])

HSP 1 Score: 54.299 bits (129), Expect = 2.057e-8
Identity = 41/142 (28.87%), Postives = 73/142 (51.41%), Query Frame = 2
Query:  104 FLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTL-LVISNQLGIIGNIIYFIAS--HP---WMVLLGR-FLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGP 508
            FL+ +  ++++ ++W +  KV  PS++  + GW LA++++A L   P  G  A+   R  ++ L+ S  LG  G+++Y  A   H    ++VL  R FL       +  + A     T++ ERTP +  L   +  G I+GP
Sbjct:   19 FLSSVGFSIVMSSIWPFLQKV-DPSSSPTFLGWVLASYSLAQLFACPALG--AWANARGSSMPLLTSMLLGTAGHVMYMYAHAVHSRGRFLVLAARIFLGLGAGTTQAVVRAFASAATNMDERTPVMANLSACQALGFILGP 157          
BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Match: EDO49760 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFQ2])

HSP 1 Score: 145.591 bits (366), Expect = 3.131e-38
Identity = 129/434 (29.72%), Postives = 205/434 (47.24%), Query Frame = 2
Query:  107 LTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRK---------SYCSD---IIDAQLKQGIEELPSPTTME-------RISNFFNPIN-----YKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336
              G+E AVI+PT+WLY S+ F     S +YG   AAF+ + L+  PLFG         K  ++ +N   + GN +YFIA   + +L GR +AG GAG    ++A I R T+ +ERT      +  RQFGL+IGP   + +K+   K+G   +D Y  PGL +A +W    IL++ +Y  L S  QN    D+ P+ T         H           S+  D    I+   K  + E+ S    +       R S+  + I       K+ ++  I+  L   F  +F+    E++  P+++    W E+E S  Y    +  IL +V++  +S R + DR L++ G+I   ++ +W  I L+     +  +  ++IV G    V G PF    + SL +K      Q   Q   R    VA+++GP  GGS+
Sbjct:   21 FAGMEYAVILPTMWLYASERFQAE--SWFYGIIFAAFSFSSLIMSPLFGMWVDYTRNTKACILFANLFEMGGNFLYFIAWSKYWILGGRLVAGIGAGVSSAIFAQIARTTTEEERTSVYSIAMGLRQFGLLIGPGMNVFLKECNFKLGPFKVDHYTSPGLFMAAIWLLQEILMIFMYYDLPSVNQN----DKEPVFTEKPQITNGLHANKEGITNGGLSHLPDNIGSINTAAKDNLCEISSLNNSDSATVHKRRSSSVSSHIVDTWRLSKELMREEIIIILASQFIMFFNETAFEALFTPLSNHLLGWKELENSVAYCLIALEAILTFVLVSKVSKR-LSDRWLMVIGVIFEGLALVWYLIMLADSKPYEAKILPTVIV-GTLIIVFGLPFFSVANISLLSKLTDDKVQGVVQGFQRSSTGVAMILGPMWGGSL 446          
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000008970.2 (major facilitator superfamily domain-containing protein 8 [Source:NCBI gene;Acc:101156398])

HSP 1 Score: 141.354 bits (355), Expect = 2.294e-36
Identity = 124/440 (28.18%), Postives = 215/440 (48.86%), Query Frame = 2
Query:  107 LTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY------PRLKSDRQNLSKSDR----------------VPLLTPMSMELEDSHRKSYCSDIIDAQLK-QGIEELP--SPTT---MERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISL--IVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSM 1336
            L+G+E AVI+PT+W Y   +   +   ++ G TL+AF+++ LL  PLFG+L+      K +++ +N   IIGN++YF+    W++L  R +AG G G    ++  + R T+ ++R      ++  RQ GL+IGPA  + ++     +G   ++ Y  PGL + +LW    ++V+ +Y       R K+    + K +                  PL+T  S EL  S+      D      +   I   P  SP T    E +++  +   Y+++L+  ++  L   F + F+   LE+++ P+  +YF + E+E S +Y   GV VI  ++ +R + S+ V +R +L  GL +  IS +W   CL  + K        L   +IG+   VLG PF      SL++K      Q  +Q + R V  +A ++GP   G +
Sbjct:   20 LSGVEYAVILPTIWRYLQTL---NAEPYFLGLTLSAFSLSGLLSGPLFGHLSDRTQTTKKIILFANFFEIIGNLMYFMGYSKWLLLSSRLVAGIGTGAGSSIFGFLTRSTASEDRATVFAAVMACRQAGLLIGPAFNIFLRLCNFHLGSFVVNKYTAPGLFMCLLWILLQLVVVFMYWDLPYLERRKTKDSVIHKEEENTHASVEDEEEGDEEVKPLMT--SQELVGSYGSVVAPDPCRKHSRVSSIHNSPISSPVTSQSHEHVTSLKSSSLYREFLREEVVVLLAAQFITLFNQTALETMVTPLTQKYFNFGELENSVMYCLGGVVVIAGFLFVRWL-SKHVAERVVLAIGLTICNISCIW---CLIFLAKPLGGFSWQLTEFIIGVFLQVLGLPFVAVAQVSLFSKITSEKTQGFSQGVRRSVGGLATILGPLWAGGL 450          
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: si:ch211-38m6.6 (major facilitator superfamily domain-containing protein 8-like [Source:NCBI gene;Acc:105356178])

HSP 1 Score: 132.109 bits (331), Expect = 4.250e-33
Identity = 123/448 (27.46%), Postives = 214/448 (47.77%), Query Frame = 2
Query:  107 LTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIY---PRLKSDRQNLS---KSDRVPLLTPM---SMELEDSHRKSYCSDIIDAQL--KQGI---------------EELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLF--ISLIVIGIGFHVLGQPF-------CISCSESLYTKQVFVGDQDR---AQSILRMVINVALLIGPFVGGSM 1336
            L+G+E AVI+PT+W Y   + +P    ++ G  L+AF+++ LL  PLFG+ +      K++++ SN   I GN +YF+    W++L  R +AG GAG    ++  + R T  +ER      ++  RQ GL+IGPA  L ++    K+G  +++ Y  PG+ + +LW     +VL +Y   P +KS+ + L    K +      P+     +L  ++R           L  K+ I               ++  +P  + R+          ++L+  ++  L   F + F+   LE+++ PM  RYF + E+  S +Y  CGV VIL +  +R +S + V DR +L  GL++   + +W   CL  +   +      ++  +IG+   +LG PF       C S    +  K V     DR   +Q + R V  +A ++GP   G +
Sbjct:   29 LSGIEYAVILPTIWRYLQILEAPP---YFLGLGLSAFSLSGLLTGPLFGFWSDRSKTTKSIILFSNLFEIAGNFMYFLGYSKWLLLCSRLVAGIGAGAGSSIFGFLTRSTLPEERAGIFAAVMACRQAGLLIGPAFNLFLRLCDFKLGPFAVNKYTSPGIFMCLLWLLLQFVVLALYWDVPPIKSEEEGLRMEMKQEDEEEEAPLIRGDEQLAHTYRAVNLDHCYQTSLFIKKSIFLMHFHCFFKTDVLQKDFVTPVKV-RVKRSLGLSVCAEFLREEVVVVLTAQFITLFNQTALETMVTPMTQRYFSFGELGNSLMYSLCGVEVILGFFFVRWLSGK-VADRAVLAGGLVICCFACVW---CLVFLCNPRGGYGWELTAFIIGVFLQLLGLPFVAVSATDCCSVCMMVTKKNV---KTDRLWFSQGVRRSVGGLATILGPLWAGGL 465          
BLAST of MFS domain-containing protein vs. Ensembl Medaka
Match: mfsd8 (major facilitator superfamily domain containing 8 [Source:NCBI gene;Acc:101161364])

HSP 1 Score: 57.7658 bits (138), Expect = 1.473e-8
Identity = 61/225 (27.11%), Postives = 110/225 (48.89%), Query Frame = 2
Query:   62 KSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHP-----WMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLM-----KDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQ-------NLSKSDRV 685
            +S+++   +  F  FL+ +   ++I +LW Y  KV S + AS + GW +AA+++  ++  PLFG+ +    R +  LV S  + +  NI Y  A  P     + +L+ R   G GAG    + + +   TSL+ERT  +  +   +  G I+GPA    +     + I + + ++ + +Y  P LL A+    + +LV+L+    + D         N +  DRV
Sbjct:   28 RSRWRSIRVMYFTMFLSSVGFTIVITSLWPYLEKVDSGADAS-FLGWMVAAYSLGQMVASPLFGWWSNHRPR-REPLVCSIFINLAANIYYAYAYLPKTNNKYHLLMSRAFVGFGAGNVAVVRSYVAGATSLRERTGAMANMSACQALGFILGPALQAGLTFIGEEGITVDVIKLQLSMYTTPALLAALFGLINILLVVLVLKEHRVDEDGKQIQAINYTSEDRV 250          
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000022267.1 (SMESG000022267.1)

HSP 1 Score: 733.406 bits (1892), Expect = 0.000e+0
Identity = 403/410 (98.29%), Postives = 406/410 (99.02%), Query Frame = 2
Query:   32 MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQ 1261
            MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLAGAGAGCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKYSILSNLFIIFSSYFSLMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRTLLLSGLILLTISYLWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYT +  +G +
Sbjct:    1 MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLAGAGAGCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKYSILSNLFIIFSSYFSLMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRTLLLSGLILLTISYLWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTNKFLLGTK 410          
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000066500.1 (SMESG000066500.1)

HSP 1 Score: 348.591 bits (893), Expect = 2.598e-115
Identity = 216/445 (48.54%), Postives = 293/445 (65.84%), Query Frame = 2
Query:   41 NCWNYVGK--SKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIID--AQLKQGIEELPSPTTMERISNFFNPIN-YKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360
             C N + K   KF I    A WGFLTG+ERA+I+PTLWLYF   F    AS YY  TLAAFN+++ L  PL+G+LA+ G R K LLVISNQL ++GNIIYF+AS PWMV++GRF+AG G+G EVPLYAD+VRVT+ +ERT YIV LLL RQ GLIIGPA TL++  IK +IG VS++IYN PG L+A+LW   TI VL+ YP +      L  S +   +  M +       K Y  ++ D  + L   I      +    I N    I+ +  Y  Y+ LS L I+FSSYF+L+ LE+VLPP+  RYF W E+  S+VYL  G  VI++Y IL+ + SR V+DR++LL+GLI L ISY+W++I L +I+  +  L+ISL+  GI FH+ G    I+C+ESL+TK +   + D AQ++LR  IN +LL+GP++ GS++    +VF
Sbjct:   27 KCENKLNKIQPKFTISVCCATWGFLTGVERAIILPTLWLYFVTKFGSQAASSYYAATLAAFNLSVFLFAPLYGFLAYKGFRTKALLVISNQLEVVGNIIYFVASEPWMVMMGRFIAGIGSGSEVPLYADVVRVTNPEERTAYIVILLLARQVGLIIGPAATLILHPIKFQIGSVSLNIYNSPGFLMAILWCVQTIQVLISYPDVDKSGALLKSSSQGKNINEMII------HKIYEKNMSDTSSHLNTEIRRDSDKSKRTFIDNAKKSIHKFSRYAHYNTLSLLAIVFSSYFALISLEAVLPPVTVRYFHWNEVHNSYVYLAAGFLVIIIYGILQSV-SRHVKDRSVLLTGLIFLLISYVWMTIILGLINSSEKILYISLMSCGIFFHIFGLSLVIACAESLFTKSLPPEEMDMAQTVLRTTINFSLLVGPYIAGSLQIFPYLVF 464          
BLAST of MFS domain-containing protein vs. Planmine SMEST
Match: SMESG000075932.1 (SMESG000075932.1)

HSP 1 Score: 323.553 bits (828), Expect = 1.453e-105
Identity = 198/432 (45.83%), Postives = 278/432 (64.35%), Query Frame = 2
Query:   74 KICFI--AAFWGFLTGLERAVIIPTLWLYFSKVFSPSTASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNIIYFIASHPWMVLLGRFLXXXXXXCEVPLYADIVRVTSLQERTPYIVTLLLFRQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLLIYPRLKSDRQNLSKSDRVPLLTPMSMELEDS-HRKSYCSDIIDAQLKQGIEELPSPTTMERISNFFNPINYKDYLKXXXXXXXXXXXXXXXXXMGLESVLPPMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRXXXXXXXXXXXXXXXWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESLYTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVF 1360
            K+C I  AA  GFL G+ER++I+P+LWLYF   F    A  YYG TL+AFN+++ +  P +GYLA  G R K LL+ISNQL IIGNIIYFIAS PWM+L GRF+ G GAG EVPLYAD+VRVT+++ERT YI+ LLL RQ GLIIGPA TL++  +K ++G ++++IYN PG ++ +LW   TI++L+IYP +  D   +         T ++M LE    +K +  +       +   E  S T   ++   FN    K Y     ++ L I F SYF L+ LES++PP+  RYF+W+E+  S++YL  G+ VI+  ++L+ +S+  V D+   + GL+LL  SYL LS  L  I+  Q NL ISL+ IGI  H+ G    I+C ESLYTK + + + D  QS+LR VIN +LL+GP+V GS++  S +VF
Sbjct:   44 KLCIIGSAASVGFLNGVERSIILPSLWLYFITKFGNEAAERYYGGTLSAFNLSVFVIAPFYGYLAQKGFRTKFLLIISNQLEIIGNIIYFIASEPWMILFGRFVCGIGAGSEVPLYADVVRVTNVKERTSYIIILLLSRQIGLIIGPAVTLILHPVKFQVGNITLNIYNSPGFIMGILWAIQTIVILIIYPEISKDGSEIDN-------TRINMRLEQRIFKKVFDGESSKTVTNEDSVEYNSITFNGKVKEIFNK--SKQYTNLVTVTLLCITFVSYFCLISLESIIPPITVRYFKWSEVHNSYLYLLAGILVIVTLLLLQKVSNY-VTDQKSYVCGLLLLICSYLILSFTLLFIESNQQNLSISLMGIGILLHIFGLSIVIACGESLYTKTLPISEMDLGQSVLRTVINFSLLVGPYVAGSLQFYSFIVF 465          
The following BLAST results are available for this feature:
BLAST of MFS domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MFSD87.686e-927.84major facilitator superfamily domain containing 8 ... [more]
MFSD87.686e-927.84major facilitator superfamily domain containing 8 ... [more]
MFSD81.530e-827.13major facilitator superfamily domain containing 8 ... [more]
MFSD81.541e-827.13major facilitator superfamily domain containing 8 ... [more]
MFSD81.541e-827.13major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Y53G8AR.73.391e-924.12pep chromosome:WBcel235:III:3282308:3290215:1 gene... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MFS domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-38m6.62.657e-3729.93si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
CABZ01045212.13.819e-3227.16major facilitator superfamily domain-containing pr... [more]
CABZ01045212.13.287e-2029.02major facilitator superfamily domain-containing pr... [more]
si:ch211-38m6.64.472e-1729.00si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
mfsd83.494e-1024.19major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
dnajc188.614e-3626.85DnaJ heat shock protein family (Hsp40) member C18 ... [more]
dnajc188.708e-3627.08DnaJ heat shock protein family (Hsp40) member C18 ... [more]
dnajc185.904e-3526.60DnaJ heat shock protein family (Hsp40) member C18 ... [more]
MFSD83.457e-927.32major facilitator superfamily domain containing 8 ... [more]
MFSD84.792e-927.32major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Mfsd83.400e-928.72major facilitator superfamily domain containing 8 ... [more]
Mfsd83.400e-928.72major facilitator superfamily domain containing 8 ... [more]
Mfsd83.430e-928.74major facilitator superfamily domain containing 8 ... [more]
Mfsd83.430e-928.74major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 4
Match NameE-valueIdentityDescription
sp|Q0VA82|MFSD8_DANRE2.638e-924.19Major facilitator superfamily domain-containing pr... [more]
sp|Q8BH31|MFSD8_MOUSE2.378e-828.72Major facilitator superfamily domain-containing pr... [more]
sp|Q6GPQ3|MFSD8_XENLA4.486e-827.23Major facilitator superfamily domain-containing pr... [more]
sp|Q8NHS3|MFSD8_HUMAN4.446e-727.13Major facilitator superfamily domain-containing pr... [more]
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BLAST of MFS domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1I8HRG68.848e-10846.24MFS domain-containing protein OS=Macrostomum ligna... [more]
A0A267FNL83.644e-10746.53MFS domain-containing protein OS=Macrostomum ligna... [more]
A0A267GD892.380e-10646.40MFS domain-containing protein OS=Macrostomum ligna... [more]
A0A448XFL84.255e-10344.67Uncharacterized protein OS=Protopolystoma xenopodi... [more]
A0A0X3PDP89.725e-10043.64Putative MFS-type transporter C330.07c OS=Schistoc... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
si:ch211-38m6.61.717e-2927.71si:ch211-38m6.6 [Source:ZFIN;Acc:ZDB-GENE-070705-1... [more]
ENSAMXT00000001851.22.140e-2926.95pep primary_assembly:Astyanax_mexicanus-2.0:5:2326... [more]
mfsd86.900e-927.89major facilitator superfamily domain containing 8 ... [more]
mfsd86.900e-626.32major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mfsd82.057e-828.87major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of MFS domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO497603.131e-3829.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of MFS domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSORLT00000008970.22.294e-3628.18major facilitator superfamily domain-containing pr... [more]
si:ch211-38m6.64.250e-3327.46major facilitator superfamily domain-containing pr... [more]
mfsd81.473e-827.11major facilitator superfamily domain containing 8 ... [more]
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BLAST of MFS domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000022267.10.000e+098.29SMESG000022267.1[more]
SMESG000066500.12.598e-11548.54SMESG000066500.1[more]
SMESG000075932.11.453e-10545.83SMESG000075932.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035820 ID=SMED30035820|Name=MFS domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1459bp
TCTGTAATTACAATTTGTCCTGAAGTCTAAAATGATAGCAAACTGTTGGA
ATTACGTAGGAAAATCCAAATTTAAAATCTGTTTTATAGCAGCATTTTGG
GGTTTTCTAACTGGACTTGAAAGAGCAGTCATTATTCCCACTCTTTGGTT
GTATTTTTCAAAAGTTTTCAGTCCATCAACCGCTTCTCACTACTATGGAT
GGACTCTTGCTGCATTCAATGTCGCCATATTGCTATGTGATCCATTGTTT
GGATATTTGGCTTTCATTGGAGTTCGAGTTAAAACTTTGCTTGTTATTTC
TAATCAATTAGGAATAATTGGAAATATTATTTATTTTATAGCATCACATC
CTTGGATGGTTTTATTGGGTCGGTTTCTTGCTGGGGCCGGTGCTGGATGT
GAAGTTCCGTTATATGCCGATATTGTTAGGGTGACATCCCTTCAAGAAAG
AACACCATATATAGTAACTTTATTATTATTTCGTCAGTTTGGCCTAATTA
TTGGGCCCGCGTGTACTTTACTAATGAAGGACATTAAAATGAAAATTGGC
CAAGTGAGTATAGACATTTACAATGGGCCCGGTTTATTACTAGCAGTATT
GTGGGGATTCCACACGATTTTAGTCCTATTGATTTATCCAAGACTGAAAT
CTGACAGACAGAATCTTTCTAAGTCTGACAGAGTGCCTCTGCTAACTCCA
ATGTCAATGGAACTTGAAGATTCACATCGAAAAAGCTACTGTAGCGATAT
TATAGATGCACAATTGAAACAAGGAATCGAAGAACTTCCGAGCCCAACAA
CAATGGAAAGAATTTCAAATTTTTTTAATCCAATTAACTATAAAGATTAT
TTGAAATATTCCATTCTATCAAATTTATTCATTATATTCTCCAGTTATTT
CAGCTTAATGGGCTTGGAATCGGTTCTACCTCCAATGGCGTCAAGATATT
TTCAATGGACTGAAATTGAAACGAGTTGGGTTTATTTAGGTTGTGGAGTA
TCAGTTATTTTAGTTTATGTGATTTTACGTCTTATCTCCAGTCGTGGAGT
TGAAGATCGGACACTTTTGTTGTCAGGACTGATTTTACTGACGATTTCTT
ATTTATGGTTGAGCATTTGCTTAAGTGTCATTGATAAAAAACAGCCGAAC
TTGTTTATTTCTTTAATAGTAATTGGAATTGGATTTCACGTTCTCGGACA
ACCGTTTTGCATTTCTTGTTCTGAATCTCTATACACCAAACAAGTTTTTG
TTGGGGACCAAGATCGAGCGCAGTCGATTCTAAGAATGGTAATTAACGTA
GCCCTTCTAATCGGACCCTTTGTTGGAGGTTCAATGGAAACAGAATCTAA
TGTTGTTTTTATTTTGCTGCTTTTATCAATTGTCATTTCAACAACTTTAC
TCATAGCAAAGTTTAGCAGATTTTCCAATGAAAATACTCAAATGGACTGA
AAGATTTTT
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protein sequence of SMED30035820-orf-1

>SMED30035820-orf-1 ID=SMED30035820-orf-1|Name=SMED30035820-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=473bp
MIANCWNYVGKSKFKICFIAAFWGFLTGLERAVIIPTLWLYFSKVFSPST
ASHYYGWTLAAFNVAILLCDPLFGYLAFIGVRVKTLLVISNQLGIIGNII
YFIASHPWMVLLGRFLAGAGAGCEVPLYADIVRVTSLQERTPYIVTLLLF
RQFGLIIGPACTLLMKDIKMKIGQVSIDIYNGPGLLLAVLWGFHTILVLL
IYPRLKSDRQNLSKSDRVPLLTPMSMELEDSHRKSYCSDIIDAQLKQGIE
ELPSPTTMERISNFFNPINYKDYLKYSILSNLFIIFSSYFSLMGLESVLP
PMASRYFQWTEIETSWVYLGCGVSVILVYVILRLISSRGVEDRTLLLSGL
ILLTISYLWLSICLSVIDKKQPNLFISLIVIGIGFHVLGQPFCISCSESL
YTKQVFVGDQDRAQSILRMVINVALLIGPFVGGSMETESNVVFILLLLSI
VISTTLLIAKFSRFSNENTQMD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0022857transmembrane transporter activity
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
Vocabulary: INTERPRO
TermDefinition
IPR011701MFS
IPR020846MFS_dom
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
Vocabulary: cellular component
TermDefinition
GO:0016021integral component of membrane
GO:0016020membrane