Nucleoporin NUP53-like

Overview
NameNucleoporin NUP53-like
Smed IDSMED30035756
Length (bp)1105
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Nucleoporin NUP53-like (SMED30035756) t-SNE clustered cells

Violin plots show distribution of expression levels for Nucleoporin NUP53-like (SMED30035756) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Nucleoporin NUP53-like (SMED30035756) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Nucleoporin NUP53-like (SMED30035756) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035756

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30035756SMESG000071542.1 SmedASXL_006987SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30035756SMESG000071542.1 SmedASXL_006987SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30035756SMESG000071542.1 SMED_02534_V2_1GPL14150_gene_modelsPMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
neoblastSMED30035756SMESG000071542.1 SMED_02534_V2_1GPL14150PMID:22385657
Wagner et al., 2012		whole organism asexual adult cDNA to DNA expression microarray evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Human
Match: NUP35 (nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797])

HSP 1 Score: 97.0561 bits (240), Expect = 3.018e-22
Identity = 40/91 (43.96%), Postives = 64/91 (70.33%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  ++  ++WVTVFG+  + A Y+L  F++ G+I++  +SN+GNWMHI+Y+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  139 DPFYTQGDSLTSEDHLDDSWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 229
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Human
Match: NUP35 (nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797])

HSP 1 Score: 97.0561 bits (240), Expect = 4.081e-22
Identity = 40/91 (43.96%), Postives = 64/91 (70.33%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  ++  ++WVTVFG+  + A Y+L  F++ G+I++  +SN+GNWMHI+Y+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  156 DPFYTQGDSLTSEDHLDDSWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 246
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Celegans
Match: npp-19 (Nucleoporin NUP35 [Source:UniProtKB/Swiss-Prot;Acc:Q09601])

HSP 1 Score: 73.9442 bits (180), Expect = 2.217e-14
Identity = 32/81 (39.51%), Postives = 52/81 (64.20%), Query Frame = 1 
Query:  547 ENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSG 789
            + WVTVFG+ PS+   +L+ FS  G ++  +  + GN++H++Y    HA  A++RNG +L+ +T IGV  C +K  DV +G
Sbjct:  198 DTWVTVFGFQPSQVSILLNLFSRHGEVVSHQTPSKGNFIHMRYSCVTHAQQAISRNGTLLDQDTFIGVVQCTNK--DVING 276
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Celegans
Match: npp-19 (Nucleoporin NUP35 [Source:UniProtKB/Swiss-Prot;Acc:Q09601])

HSP 1 Score: 73.9442 bits (180), Expect = 2.609e-14
Identity = 32/81 (39.51%), Postives = 52/81 (64.20%), Query Frame = 1 
Query:  547 ENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSG 789
            + WVTVFG+ PS+   +L+ FS  G ++  +  + GN++H++Y    HA  A++RNG +L+ +T IGV  C +K  DV +G
Sbjct:  198 DTWVTVFGFQPSQVSILLNLFSRHGEVVSHQTPSKGNFIHMRYSCVTHAQQAISRNGTLLDQDTFIGVVQCTNK--DVING 276
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Fly
Match: Nup35 (gene:FBgn0030943 transcript:FBtr0074601)

HSP 1 Score: 69.707 bits (169), Expect = 5.612e-13
Identity = 45/167 (26.95%), Postives = 75/167 (44.91%), Query Frame = 1 
Query:  553 WVTVFGYAPSEARYVLSYFSEIGSIIEQ-KISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK-------VTDVPSGNRFKERSIIGQSIDSPNSSRLLEEPLPVNGSSSILTTDKFNCSMLNLSMRSLSQSNFPSPVKTEERPKGGLLSRAMSMVF 1029
            WVT+FG+ P     VL +F+  G+I++      +GNWM+++Y S++ +  ALN N +I+  N M+GV  C D+       +  VP+         IG    SP++ R   +                       S +   + N  SP K   +   GL+ +AM ++F
Sbjct:  192 WVTIFGFPPGAGSMVLQHFTVCGTIVDVVHAPQNGNWMYVRYSSRIESDKALNYNEKIIAGNVMVGVSRCTDRSVIDKENIGSVPNAE-------IGDPPTSPSAIRPFSQ----------------------QSYKLARKDNIISPQKDVPQKSSGLMDKAMDLIF 329
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Zebrafish
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:337461])

HSP 1 Score: 99.7525 bits (247), Expect = 1.724e-23
Identity = 39/80 (48.75%), Postives = 61/80 (76.25%), Query Frame = 1 
Query:  532 SENEFEN-WVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            SE++ ++ W+TVFG+ P+ A Y+L  F++ G+I++  +SN+GNWMH+QY+SK+ A  AL+++G+I     MIGVKPC DK
Sbjct:  143 SEDQLDDTWITVFGFPPASASYILLQFAQYGNILKHVMSNTGNWMHVQYQSKLQARKALSKDGKIFGEAIMIGVKPCIDK 222
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Zebrafish
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:337461])

HSP 1 Score: 99.7525 bits (247), Expect = 2.417e-23
Identity = 39/80 (48.75%), Postives = 61/80 (76.25%), Query Frame = 1 
Query:  532 SENEFEN-WVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            SE++ ++ W+TVFG+ P+ A Y+L  F++ G+I++  +SN+GNWMH+QY+SK+ A  AL+++G+I     MIGVKPC DK
Sbjct:  152 SEDQLDDTWITVFGFPPASASYILLQFAQYGNILKHVMSNTGNWMHVQYQSKLQARKALSKDGKIFGEAIMIGVKPCIDK 231
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Zebrafish
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:337461])

HSP 1 Score: 81.2629 bits (199), Expect = 1.966e-17
Identity = 31/71 (43.66%), Postives = 53/71 (74.65%), Query Frame = 1 
Query:  532 SENEFEN-WVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTM 741
            SE++ ++ W+TVFG+ P+ A Y+L  F++ G+I++  +SN+GNWMH+QY+SK+ A  AL+++G+I     M
Sbjct:  157 SEDQLDDTWITVFGFPPASASYILLQFAQYGNILKHVMSNTGNWMHVQYQSKLQARKALSKDGKIFGEAIM 227
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Zebrafish
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:337461])

HSP 1 Score: 65.4698 bits (158), Expect = 7.986e-12
Identity = 31/80 (38.75%), Postives = 50/80 (62.50%), Query Frame = 1 
Query:  532 SENEFEN-WVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            SE++ ++ W+TVFG+ P+ A Y+L  F++ G+I++          H+   SK+ A  AL+++G+I     MIGVKPC DK
Sbjct:  152 SEDQLDDTWITVFGFPPASASYILLQFAQYGNILK----------HV---SKLQARKALSKDGKIFGEAIMIGVKPCIDK 218
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Xenopus
Match: fshb (follicle stimulating hormone subunit beta [Source:Xenbase;Acc:XB-GENE-484695])

HSP 1 Score: 98.9821 bits (245), Expect = 7.196e-23
Identity = 42/91 (46.15%), Postives = 62/91 (68.13%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  +   + WVTVFG+  + A Y+L  F++ G+II+  +SN+GNWMHIQY+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  144 DPFYTQGDALTSDDQLDDTWVTVFGFPQASASYILLQFAQYGNIIKHVMSNNGNWMHIQYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 234
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Xenopus
Match: fshb (follicle stimulating hormone subunit beta [Source:Xenbase;Acc:XB-GENE-484695])

HSP 1 Score: 98.9821 bits (245), Expect = 7.503e-23
Identity = 42/91 (46.15%), Postives = 62/91 (68.13%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  +   + WVTVFG+  + A Y+L  F++ G+II+  +SN+GNWMHIQY+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  150 DPFYTQGDALTSDDQLDDTWVTVFGFPQASASYILLQFAQYGNIIKHVMSNNGNWMHIQYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 240
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Xenopus
Match: fshb (follicle stimulating hormone subunit beta [Source:Xenbase;Acc:XB-GENE-484695])

HSP 1 Score: 98.9821 bits (245), Expect = 7.803e-23
Identity = 42/91 (46.15%), Postives = 62/91 (68.13%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  +   + WVTVFG+  + A Y+L  F++ G+II+  +SN+GNWMHIQY+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  148 DPFYTQGDALTSDDQLDDTWVTVFGFPQASASYILLQFAQYGNIIKHVMSNNGNWMHIQYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 238
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Xenopus
Match: fshb (follicle stimulating hormone subunit beta [Source:Xenbase;Acc:XB-GENE-484695])

HSP 1 Score: 98.5969 bits (244), Expect = 8.922e-23
Identity = 42/91 (46.15%), Postives = 62/91 (68.13%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  +   + WVTVFG+  + A Y+L  F++ G+II+  +SN+GNWMHIQY+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  155 DPFYTQGDALTSDDQLDDTWVTVFGFPQASASYILLQFAQYGNIIKHVMSNNGNWMHIQYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 245
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Xenopus
Match: fshb (follicle stimulating hormone subunit beta [Source:Xenbase;Acc:XB-GENE-484695])

HSP 1 Score: 98.9821 bits (245), Expect = 9.402e-23
Identity = 42/91 (46.15%), Postives = 62/91 (68.13%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  +   + WVTVFG+  + A Y+L  F++ G+II+  +SN+GNWMHIQY+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  160 DPFYTQGDALTSDDQLDDTWVTVFGFPQASASYILLQFAQYGNIIKHVMSNNGNWMHIQYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 250
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Mouse
Match: Nup35 (nucleoporin 35 [Source:MGI Symbol;Acc:MGI:1916732])

HSP 1 Score: 97.0561 bits (240), Expect = 2.708e-22
Identity = 40/91 (43.96%), Postives = 63/91 (69.23%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  ++  + WVTVFG+  + A Y+L  F++ G+I++  +SN+GNWMHI+Y+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  155 DPFYTQGDSLTSEDHLDDTWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 245
[Close]
BLAST of Nucleoporin NUP53-like vs. UniProt/SwissProt
Match: sp|Q6P6X9|NUP35_DANRE (Nucleoporin NUP35 OS=Danio rerio OX=7955 GN=nup35 PE=1 SV=1)

HSP 1 Score: 99.7525 bits (247), Expect = 1.825e-22
Identity = 39/80 (48.75%), Postives = 61/80 (76.25%), Query Frame = 1 
Query:  532 SENEFEN-WVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            SE++ ++ W+TVFG+ P+ A Y+L  F++ G+I++  +SN+GNWMH+QY+SK+ A  AL+++G+I     MIGVKPC DK
Sbjct:  152 SEDQLDDTWITVFGFPPASASYILLQFAQYGNILKHVMSNTGNWMHVQYQSKLQARKALSKDGKIFGEAIMIGVKPCIDK 231
[Close]
BLAST of Nucleoporin NUP53-like vs. UniProt/SwissProt
Match: sp|Q66IJ0|NUP35_XENTR (Nucleoporin NUP35 OS=Xenopus tropicalis OX=8364 GN=nup35 PE=2 SV=1)

HSP 1 Score: 98.5969 bits (244), Expect = 5.008e-22
Identity = 42/91 (46.15%), Postives = 62/91 (68.13%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  +   + WVTVFG+  + A Y+L  F++ G+II+  +SN+GNWMHIQY+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  159 DPFYTQGDALTSDDQLDDTWVTVFGFPQASASYILLQFAQYGNIIKHVMSNNGNWMHIQYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 249
[Close]
BLAST of Nucleoporin NUP53-like vs. UniProt/SwissProt
Match: sp|Q8R4R6|NUP35_MOUSE (Nucleoporin NUP35 OS=Mus musculus OX=10090 GN=Nup35 PE=1 SV=2)

HSP 1 Score: 97.0561 bits (240), Expect = 1.894e-21
Identity = 40/91 (43.96%), Postives = 63/91 (69.23%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  ++  + WVTVFG+  + A Y+L  F++ G+I++  +SN+GNWMHI+Y+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  155 DPFYTQGDSLTSEDHLDDTWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 245
[Close]
BLAST of Nucleoporin NUP53-like vs. UniProt/SwissProt
Match: sp|Q8NFH5|NUP35_HUMAN (Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1)

HSP 1 Score: 97.0561 bits (240), Expect = 1.960e-21
Identity = 40/91 (43.96%), Postives = 64/91 (70.33%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  ++  ++WVTVFG+  + A Y+L  F++ G+I++  +SN+GNWMHI+Y+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  156 DPFYTQGDSLTSEDHLDDSWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 246
[Close]
BLAST of Nucleoporin NUP53-like vs. UniProt/SwissProt
Match: sp|Q68FY1|NUP35_RAT (Nucleoporin NUP35 OS=Rattus norvegicus OX=10116 GN=Nup35 PE=1 SV=1)

HSP 1 Score: 96.6709 bits (239), Expect = 2.307e-21
Identity = 40/91 (43.96%), Postives = 63/91 (69.23%), Query Frame = 1 
Query:  496 NSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            + F  + +  T  ++  + WVTVFG+  + A Y+L  F++ G+I++  +SN+GNWMHI+Y+SK+ A  AL+++GRI   + MIGVKPC DK
Sbjct:  155 DPFYTQGDSLTSEDHLDDTWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDK 245
[Close]
BLAST of Nucleoporin NUP53-like vs. TrEMBL
Match: T1J9E2 (Nucleoporin NUP53 OS=Strigamia maritima OX=126957 PE=3 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 2.655e-23
Identity = 70/224 (31.25%), Postives = 115/224 (51.34%), Query Frame = 1 
Query:  283 TSRNVGPPI-------------TTLRNKSPKNPYIKNVDLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSGNRFKERSIIGQSIDSPNSSRLLEEPLPVNGSSSILTTDKFNC 915
            T +N GPPI             T+L   S   P  KN     ++SFY ++  TP K++  V    P +S      S  +     + F  + +  T ++   E WVT+FG+ P+ + Y+L  F   G+I+E ++  SGNWMH++Y++K+ A  AL++NG++   N M+GVKPC DK   V   ++   +      ++SPN+SR+L+     NG+ S   +  F+ 
Sbjct:  110 TDKNGGPPIQGLFEYSTPTSARTSLVGGSVSPPQFKN-----NSSFYVSTTTTPAKVDTMVGHEHPGKSF-----SYAQSPAQIDPFYTQGQCLTSNDQLDETWVTIFGFPPAASSYILQQFYHYGTIVEHRLPPSGNWMHVRYQTKLQAKIALSKNGKVFG-NYMVGVKPCIDKSIIVQYVSKMPTK-----EMESPNASRILQ-----NGNQSPFASADFSV 312
[Close]
BLAST of Nucleoporin NUP53-like vs. TrEMBL
Match: A0A5K3EK65 (Uncharacterized protein OS=Mesocestoides corti OX=53468 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.019e-22
Identity = 105/363 (28.93%), Postives = 157/363 (43.25%), Query Frame = 1 
Query:   97 AMDVSCSPQ-------SGFMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYNETSRNVGPPITTL-----RNKSPKNPYIKNVDLANDTSFYGNSYAT----PGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVK---------------PCDDKVTDVPSGNRFKERSIIGQSIDSPNSSR-----LLEEPLPVNGSSSILTTDKFNCSMLNL----SMRSLSQSNFPSP------------VKTEERPKGGLLSRAMSMVF 1029
            AM V   PQ       S F+P FL+G+      F+S      PS     S   K+P  S + +   Y +   +   P+ TL     R+ SP    + +          G+S ++    P K  +   SV P   + K   ++  ++ S    LV+N+ +   ++E   W+TVFGY P++A  VL  FS  G+I +  I+N GNWMHI+Y +K+HA  ALN+NGR+   N MIGV+               PC+    DV S   FK  +   +S+      R      ++ PL +N S S  T     C    L    SMR L+ +  P P             + +     GL S+A+  VF
Sbjct:   25 AMTVGSPPQQSNTPSGSKFLPGFLMGD------FHST-----PSERFHASSFTKSPPCSPVPQHPRYLQARLSGLKPVPTLDRSSRRHASPPTQGLWSAASQKKLVELGDSQSSVEPMPTKSPKPTSSVYPRFGTPK--TASPFENTSSKEGLVENDWSFLPDDESATWITVFGYNPAQASSVLQQFSHFGTIQKYLITNEGNWMHIKYANKIHAKCALNKNGRVFPGNIMIGVRRCTDTEVMRSAAAVAPCNSNPIDVSSHEIFKSPAPKFESLAPTAEPRSKTATAVDSPLQLNHSFSDATKQNSVCPNPGLSRHSSMRPLAAAYQPPPRVQVSRTNQAQSFRVKPSKPAGLFSKALDYVF 374
[Close]
BLAST of Nucleoporin NUP53-like vs. TrEMBL
Match: A0A5N5ST42 (Nucleoporin NUP53 OS=Armadillidium nasatum OX=96803 GN=nup35 PE=4 SV=1)

HSP 1 Score: 107.842 bits (268), Expect = 1.153e-22
Identity = 71/234 (30.34%), Postives = 121/234 (51.71%), Query Frame = 1 
Query:  130 FMPNFLIGNNNHNDSFYSNQSKVQPSMHNF---ISFEKKTPRSSSLKRRESYNETSR-----NVGPPITTLRNKSPKNPYIKN-----VD----LANDTSFYGN----SYATPGKLNQ-SVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDD 765
            F P++L+G    + S       + P  H      S    +P S  L  RES+  ++R       GPPI +L    P++P  K+     +D    +A  TS+  N    +++TP   +Q S+++  P+  ++  +     ++      +V+      SE   + WVTV+G+  + A Y+L+ F+++G+II+Q+    GNWMH++Y++K+ A  AL +NG+I N N MIGV PC D
Sbjct:   42 FYPSYLMGETQTSLSTRMPPGSISPGRHARQFSASAGLSSPSSPQLGGRESFFSSTRIGGERQGGPPIVSLMGGLPQSPVTKHHSMPIIDHQKIIATPTSYMLNQNPTAFSTPVNTSQTSMQNFTPYTPTRDNVIGMCSET------IVQG-----SEPLEDTWVTVYGFPVASASYILTQFAQLGTIIDQRQPGLGNWMHLKYQTKLQARKALTKNGKIFNGNIMIGVVPCTD 264
[Close]
BLAST of Nucleoporin NUP53-like vs. TrEMBL
Match: A0A2P2I3Y0 (Nucleoporin NUP53-like (Fragment) OS=Hirondellea gigas OX=1518452 PE=2 SV=1)

HSP 1 Score: 106.686 bits (265), Expect = 3.646e-22
Identity = 58/169 (34.32%), Postives = 94/169 (55.62%), Query Frame = 1 
Query:  547 ENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSGNRFKERSIIGQSIDSPNSSRLLEEPLPVNG-SSSILTTDKFNCSMLNLSMRSLSQSNFPSPVKTEERPK-------GGLLSRAMSMVF 1029
            + WVTVFG+  + A Y+L+ F+++G+I +Q++  SGNWMH++Y++ + A  AL  NG+I + N MIGV PC+D+   +   N+  +R          NSS ++    P  G +S ILT D    S     +RSL+Q+   +PV+ +  P         G +S+AM  + 
Sbjct:  207 DEWVTVFGFPVASASYILTQFAQLGTIADQRLPGSGNWMHLKYQTSLQARKALALNGKIFSANIMIGVVPCNDRSVVMADANKENQRMFA-------NSSIIMS---PAAGNASGILTGDAAALSTPKSGIRSLTQTYQTTPVENQVVPSTNTPKKNDGFMSKAMQHIL 365
[Close]
BLAST of Nucleoporin NUP53-like vs. TrEMBL
Match: A0A068YEE9 (Nucleoporin nup53 OS=Echinococcus multilocularis OX=6211 GN=EmuJ_001064600 PE=4 SV=1)

HSP 1 Score: 107.071 bits (266), Expect = 4.162e-22
Identity = 76/233 (32.62%), Postives = 123/233 (52.79%), Query Frame = 1 
Query:  115 SPQSGFMPNFLIGN------NNHNDS-FYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYNETSR-NVGPPITTLRNKSPKNPYI--KNVDLANDTSFYGNSYATPGK------LNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDD 765
            SPQ  ++P FL+G+      N H  S  + +Q  +  S H ++      PR S LK   S   ++R +  PP  +L + + +   +   NV  A++++    S  +P +         + R   PF+S  ++  STL  S        ++   +  ++E   WVTVFGY P++A YVL +F+ +G+I +  I+N GNWM+I+Y +K+ A  ALN+NGR+L    MIGV+ CDD
Sbjct:   41 SPQ--YLPGFLMGDSQSSCTNGHQVSPIFKSQPHLPTSHHTWV----VQPRLSGLKTPPSLERSARRHAAPPTQSLWSSASQKKLLNSGNVPSASESTAK-RSLLSPSQPMVIRTATDTSRFFSPFQSPSQM--STLDRSH-------RDGHPSAPDDESATWVTVFGYDPAQANYVLQHFAHLGTIEKYVIANGGNWMNIKYANKIQARCALNKNGRVLAGKFMIGVRRCDD 257
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Cavefish
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:103032603])

HSP 1 Score: 101.679 bits (252), Expect = 3.683e-24
Identity = 42/80 (52.50%), Postives = 60/80 (75.00%), Query Frame = 1 
Query:  532 SENEF-ENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            SE++  E WVTVFG+ P+ A Y+L  F++ G+I++  +SN+GNWMHIQY+SK+ A  AL+++G+I     MIGVKPC DK
Sbjct:  148 SEDQLDETWVTVFGFPPASASYILLQFAQYGNILKHVMSNAGNWMHIQYQSKLQARKALSKDGKIFGEAIMIGVKPCIDK 227
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Cavefish
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:103032603])

HSP 1 Score: 101.679 bits (252), Expect = 4.367e-24
Identity = 42/80 (52.50%), Postives = 60/80 (75.00%), Query Frame = 1 
Query:  532 SENEF-ENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            SE++  E WVTVFG+ P+ A Y+L  F++ G+I++  +SN+GNWMHIQY+SK+ A  AL+++G+I     MIGVKPC DK
Sbjct:  159 SEDQLDETWVTVFGFPPASASYILLQFAQYGNILKHVMSNAGNWMHIQYQSKLQARKALSKDGKIFGEAIMIGVKPCIDK 238
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Sea Lamprey
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:337461])

HSP 1 Score: 97.0561 bits (240), Expect = 4.357e-23
Identity = 65/225 (28.89%), Postives = 108/225 (48.00%), Query Frame = 1 
Query:  130 FMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYNET-----SRNVGPPITTLRNKSPKNPYIK----NVDLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLN---STLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            F+P FL+G+         + +  QP  H+  +   +  RSS    R +          ++  PP+ +L +    +P       N  L + T   G+   TPG    ++ S   F      L+   +T       + F  + E    S+     WVTVFG+ P+ A Y+L  F++ G+I++  +S+SGNWMHIQY+S + A  AL+++G++     M+GVKPC +K
Sbjct:   30 FLPGFLLGD-------LPSPATGQPRSHHTPTTGLEL-RSSPFTGRSTPQAALPVTKDKSGAPPVRSLYDDVQPSPLQARNRMNTSL-HHTPLSGSVVRTPGSNKTALGSSSLFSPGTLPLSQPRATPPSPAQLDPFYTQGESLVSSDTLDHTWVTVFGFPPASASYILMQFAQYGNILKHVMSSSGNWMHIQYQSALQARKALSKDGKVFGECIMVGVKPCIEK 245
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Nematostella
Match: EDO31992 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWD1])

HSP 1 Score: 93.5893 bits (231), Expect = 3.458e-22
Identity = 64/198 (32.32%), Postives = 98/198 (49.49%), Query Frame = 1 
Query:  286 SRNVGPPITTLRNKSPKNPYIKNVDLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK--VTDVPSGN--RFKERSIIGQSIDSPNSSRLLEEPL 867
            +R+  P     ++   KNP   N         Y +   TP + ++   SV  F  SK  L  +    D    F  + E  +  +   + WVTVFG+ P+   Y+L  F++ G+II  ++  + NWMHIQY+SK+ A  AL++NG++ + N MIGV PC +K  + D    N  R  E S +  S++    SRL   PL
Sbjct:   17 TRHASPAPVNFQSTPSKNPMAGN-------HVYASGPGTPFQDSRQDTSV--FSPSKMTLPPSPTQVDP---FYTQGESLSSDDVLSQCWVTVFGFPPAATSYILQQFAQYGNIIRHEVVANKNWMHIQYQSKLQAKKALSKNGKVYSSNIMIGVMPCIEKSLMEDCGKENTMRHMETSKMDVSVNPATPSRLPIRPL 202
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Medaka
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:101158733])

HSP 1 Score: 95.1301 bits (235), Expect = 5.761e-22
Identity = 68/229 (29.69%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  109 SCSPQSG--FMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYNETSRNVGPP----ITTLRNKSPKNPYIKNV--DLAN-DTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            S  P SG  F+P FL+G+           +  QP      SF   TP S S   + ++      VG P    + T ++KS   P ++++  DL    T    +  + P  + QS  S +   +    +          + F  + E  +  +   + WVTVFG+ P+ A Y+L  F++ G+I + K+++ GNWMH+QY+SK+ A  AL+++G++   + M+GVKPC DK
Sbjct:    8 SPKPTSGAQFLPGFLLGD-------LPAPASPQPR-----SFSLSTPISES---KSAHRGGPGGVGSPMQPVVPTPKDKS-GAPPVRSIHDDLVTMGTPLGAHRQSFP--VMQSPLSGRQASTPGTGMQQVCMSPAQVDPFYSQGESLSSDDQLDQTWVTVFGFPPASASYILLQFAQYGNIQKHKMASPGNWMHLQYQSKLQARKALSKDGKVFGDSIMVGVKPCIDK 218
[Close]
BLAST of Nucleoporin NUP53-like vs. Ensembl Medaka
Match: nup35 (nucleoporin 35 [Source:NCBI gene;Acc:101158733])

HSP 1 Score: 95.1301 bits (235), Expect = 5.980e-22
Identity = 68/229 (29.69%), Postives = 113/229 (49.34%), Query Frame = 1 
Query:  109 SCSPQSG--FMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYNETSRNVGPP----ITTLRNKSPKNPYIKNV--DLAN-DTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDK 768
            S  P SG  F+P FL+G+           +  QP      SF   TP S S   + ++      VG P    + T ++KS   P ++++  DL    T    +  + P  + QS  S +   +    +          + F  + E  +  +   + WVTVFG+ P+ A Y+L  F++ G+I + K+++ GNWMH+QY+SK+ A  AL+++G++   + M+GVKPC DK
Sbjct:   17 SPKPTSGAQFLPGFLLGD-------LPAPASPQPR-----SFSLSTPISES---KSAHRGGPGGVGSPMQPVVPTPKDKS-GAPPVRSIHDDLVTMGTPLGAHRQSFP--VMQSPLSGRQASTPGTGMQQVCMSPAQVDPFYSQGESLSSDDQLDQTWVTVFGFPPASASYILLQFAQYGNIQKHKMASPGNWMHLQYQSKLQARKALSKDGKVFGDSIMVGVKPCIDK 227
[Close]
BLAST of Nucleoporin NUP53-like vs. Planmine SMEST
Match: SMESG000071542.1 (SMESG000071542.1)

HSP 1 Score: 634.024 bits (1634), Expect = 0.000e+0
Identity = 311/313 (99.36%), Postives = 312/313 (99.68%), Query Frame = 1 
Query:  100 MDVSCSPQSGFMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYNETSRNVGPPITTLRNKSPKNPYIKNVDLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSGNRFKERSIIGQSIDSPNSSRLLEEPLPVNGSSSILTTDKFNCSMLNLSMRSLSQSNFPSPVKTEERPKGGLLSRAMSMVFRRS 1038
            MDVSCSPQSGFMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESY+ETSRNVGPPITTLRNKSPKNPYIKNVDLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSGNRFKERSIIGQSIDSPNSSRLLEEPLPV GSSSILTTDKFNCSMLNLSMRSLSQSNFPSPVKTEERPKGGLLSRAMSMVFRRS
Sbjct:    1 MDVSCSPQSGFMPNFLIGNNNHNDSFYSNQSKVQPSMHNFISFEKKTPRSSSLKRRESYHETSRNVGPPITTLRNKSPKNPYIKNVDLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFLVKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGNWMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSGNRFKERSIIGQSIDSPNSSRLLEEPLPVIGSSSILTTDKFNCSMLNLSMRSLSQSNFPSPVKTEERPKGGLLSRAMSMVFRRS 313
The following BLAST results are available for this feature:
BLAST of Nucleoporin NUP53-like vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 2
Match NameE-valueIdentityDescription
NUP353.018e-2243.96nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797][more]
NUP354.081e-2243.96nucleoporin 35 [Source:HGNC Symbol;Acc:HGNC:29797][more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
npp-192.217e-1439.51Nucleoporin NUP35 [Source:UniProtKB/Swiss-Prot;Ac... [more]
npp-192.609e-1439.51Nucleoporin NUP35 [Source:UniProtKB/Swiss-Prot;Ac... [more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Nup355.612e-1326.95gene:FBgn0030943 transcript:FBtr0074601[more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
nup351.724e-2348.75nucleoporin 35 [Source:NCBI gene;Acc:337461][more]
nup352.417e-2348.75nucleoporin 35 [Source:NCBI gene;Acc:337461][more]
nup351.966e-1743.66nucleoporin 35 [Source:NCBI gene;Acc:337461][more]
nup357.986e-1238.75nucleoporin 35 [Source:NCBI gene;Acc:337461][more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
fshb7.196e-2346.15follicle stimulating hormone subunit beta [Source:... [more]
fshb7.503e-2346.15follicle stimulating hormone subunit beta [Source:... [more]
fshb7.803e-2346.15follicle stimulating hormone subunit beta [Source:... [more]
fshb8.922e-2346.15follicle stimulating hormone subunit beta [Source:... [more]
fshb9.402e-2346.15follicle stimulating hormone subunit beta [Source:... [more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Nup352.708e-2243.96nucleoporin 35 [Source:MGI Symbol;Acc:MGI:1916732][more]
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BLAST of Nucleoporin NUP53-like vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6P6X9|NUP35_DANRE1.825e-2248.75Nucleoporin NUP35 OS=Danio rerio OX=7955 GN=nup35 ... [more]
sp|Q66IJ0|NUP35_XENTR5.008e-2246.15Nucleoporin NUP35 OS=Xenopus tropicalis OX=8364 GN... [more]
sp|Q8R4R6|NUP35_MOUSE1.894e-2143.96Nucleoporin NUP35 OS=Mus musculus OX=10090 GN=Nup3... [more]
sp|Q8NFH5|NUP35_HUMAN1.960e-2143.96Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35... [more]
sp|Q68FY1|NUP35_RAT2.307e-2143.96Nucleoporin NUP35 OS=Rattus norvegicus OX=10116 GN... [more]
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BLAST of Nucleoporin NUP53-like vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1J9E22.655e-2331.25Nucleoporin NUP53 OS=Strigamia maritima OX=126957 ... [more]
A0A5K3EK651.019e-2228.93Uncharacterized protein OS=Mesocestoides corti OX=... [more]
A0A5N5ST421.153e-2230.34Nucleoporin NUP53 OS=Armadillidium nasatum OX=9680... [more]
A0A2P2I3Y03.646e-2234.32Nucleoporin NUP53-like (Fragment) OS=Hirondellea g... [more]
A0A068YEE94.162e-2232.62Nucleoporin nup53 OS=Echinococcus multilocularis O... [more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nup353.683e-2452.50nucleoporin 35 [Source:NCBI gene;Acc:103032603][more]
nup354.367e-2452.50nucleoporin 35 [Source:NCBI gene;Acc:103032603][more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
nup354.357e-2328.89nucleoporin 35 [Source:NCBI gene;Acc:337461][more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Nucleoporin NUP53-like vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO319923.458e-2232.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Nucleoporin NUP53-like vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2
Match NameE-valueIdentityDescription
nup355.761e-2229.69nucleoporin 35 [Source:NCBI gene;Acc:101158733][more]
nup355.980e-2229.69nucleoporin 35 [Source:NCBI gene;Acc:101158733][more]
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BLAST of Nucleoporin NUP53-like vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1
Match NameE-valueIdentityDescription
SMESG000071542.10.000e+099.36SMESG000071542.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035756 ID=SMED30035756|Name=Nucleoporin NUP53-like|organism=Schmidtea mediterranea sexual|type=transcript|length=1105bp
CTCTTGAATTAACTTGTTTAAATATCGACCATTTTTAACATTTTTCGAGT
GAAAGAAATGCGTAAAAATTATAATATTCCATTGAATGATAATTCAGCAA
TGGACGTTAGTTGTTCTCCACAATCTGGCTTTATGCCTAATTTTTTAATT
GGTAATAATAATCATAACGATTCATTCTATTCGAATCAGTCTAAGGTTCA
ACCTTCAATGCATAATTTTATTTCATTTGAAAAAAAAACACCCAGATCTT
CTTCTTTAAAACGTCGTGAATCATATAACGAAACATCTCGAAATGTTGGT
CCTCCAATTACTACTCTCAGAAATAAATCTCCAAAAAATCCTTATATTAA
GAATGTAGATCTTGCCAATGATACTAGTTTTTATGGAAACAGTTATGCTA
CACCTGGGAAATTAAATCAATCTGTCAGAAGTGTTAAACCATTTGAAAGC
AGTAAAAAGCTGCTTAATTCTACACTGAAAGACAGTGATTCCTATAATTC
GTTTCTAGTTAAAAATGAGCCAACAACATTTTCCGAAAACGAATTCGAAA
ACTGGGTTACAGTATTCGGTTATGCTCCAAGTGAAGCGAGATATGTATTG
TCATATTTTTCAGAAATCGGAAGTATCATTGAACAAAAGATCTCAAACAG
CGGTAATTGGATGCACATTCAATATGAAAGCAAAATGCACGCGGTAGCGG
CGCTGAATCGAAACGGCCGAATACTCAATCTAAACACGATGATAGGAGTG
AAACCTTGCGATGACAAAGTGACAGACGTTCCATCTGGTAATCGATTTAA
AGAGCGATCAATTATTGGCCAGTCGATTGACAGTCCAAATTCCAGTCGGT
TGCTAGAGGAACCGTTACCAGTCAACGGGTCGAGTTCTATTTTGACAACA
GACAAATTCAATTGCAGCATGTTGAATCTATCAATGCGTTCATTGAGTCA
AAGCAATTTCCCCAGTCCGGTCAAGACTGAGGAGCGCCCGAAAGGCGGAT
TGTTGAGCCGAGCCATGTCAATGGTGTTCAGAAGGTCGTGAAACTATTTG
CATTCTATCCTGACTACATTTGATGTTTATAAGAGAATAAAAATTATTTT
GTTAT
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protein sequence of SMED30035756-orf-1

>SMED30035756-orf-1 ID=SMED30035756-orf-1|Name=SMED30035756-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=328bp
MRKNYNIPLNDNSAMDVSCSPQSGFMPNFLIGNNNHNDSFYSNQSKVQPS
MHNFISFEKKTPRSSSLKRRESYNETSRNVGPPITTLRNKSPKNPYIKNV
DLANDTSFYGNSYATPGKLNQSVRSVKPFESSKKLLNSTLKDSDSYNSFL
VKNEPTTFSENEFENWVTVFGYAPSEARYVLSYFSEIGSIIEQKISNSGN
WMHIQYESKMHAVAALNRNGRILNLNTMIGVKPCDDKVTDVPSGNRFKER
SIIGQSIDSPNSSRLLEEPLPVNGSSSILTTDKFNCSMLNLSMRSLSQSN
FPSPVKTEERPKGGLLSRAMSMVFRRS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0006913nucleocytoplasmic transport
GO:0055085transmembrane transport
GO:0006810transport
GO:0015031protein transport
GO:0051028mRNA transport
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR035979RBD_domain_sf
IPR017389Nucleoporin_NUP53
IPR007846RRM_NUP35_dom
IPR012677Nucleotide-bd_a/b_plait_sf
Vocabulary: cellular component
TermDefinition
GO:0031965nuclear membrane
GO:0005634nucleus
GO:0005643nuclear pore
Vocabulary: molecular function
TermDefinition
GO:0000166nucleotide binding
GO:0003676nucleic acid binding
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR007846RNA-recognition motif (RRM) Nup35-type domainPFAMPF05172Nup35_RRMcoord: 162..240
e-value: 1.9E-20
score: 72.7
IPR007846RNA-recognition motif (RRM) Nup35-type domainPROSITEPS51472RRM_NUP35coord: 161..241
score: 29.591
IPR017389Nucleoporin, NUP53PIRSFPIRSF038119NUP53coord: 8..325
e-value: 1.1E-32
score: 111.9
IPR012677Nucleotide-binding alpha-beta plait domain superfamilyGENE3DG3DSA:3.30.70.330coord: 162..234
e-value: 2.8E-26
score: 93.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 62..76
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 59..92
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 78..92
NoneNo IPR availablePANTHERPTHR21527:SF6NUCLEOPORIN NUP35coord: 34..324
NoneNo IPR availablePANTHERPTHR21527FAMILY NOT NAMEDcoord: 34..324
NoneNo IPR availableCDDcd12441RRM_Nup53_likecoord: 164..236
e-value: 7.45091E-31
score: 109.238
IPR035979RNA-binding domain superfamilySUPERFAMILYSSF54928RNA-binding domain, RBDcoord: 165..237