Cylindromatosis (turban tumor syndrome), b
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035733 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 70Note: Hover over icons to view figure legend
Homology
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584]) HSP 1 Score: 163.31 bits (412), Expect = 8.840e-40 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 484 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584]) HSP 1 Score: 163.31 bits (412), Expect = 8.840e-40 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 484 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584]) HSP 1 Score: 163.31 bits (412), Expect = 9.541e-40 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 481 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584]) HSP 1 Score: 163.31 bits (412), Expect = 9.541e-40 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 481 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Human
Match: CYLD (CYLD lysine 63 deubiquitinase [Source:HGNC Symbol;Acc:HGNC:2584]) HSP 1 Score: 163.31 bits (412), Expect = 9.541e-40 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 481 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Celegans
Match: cyld-1 (CYLinDromatosis (Human disease gene) homolog [Source:UniProtKB/TrEMBL;Acc:H2L265]) HSP 1 Score: 131.724 bits (330), Expect = 1.832e-30 Identity = 124/463 (26.78%), Postives = 199/463 (42.98%), Query Frame = 2
Query: 4496 GTVKWTGV---DENDCYFFG--LELDDRINIGTDGTFGGQRLFTCQNGHGVLAPL----NNVASDTRFTAKVVSPENVKKSETSDQIV-----------------CGLNSSV--IAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENV-STLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTC-LGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVF--------------MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSL 5749
G V+W G DE D ++LD+ + + GVL P+ +N + + A VV S+T + I CG+ + + G KGIQG NSCY D+ L+A+FV++ D+L+ I E ++F++I+A IV+PLRK +V H ++R ++ + + +E D E + + SK+ E + +I N K +S ++ + D TS+ +L+ M + F + P LIMQ PR + + LPL I+I+ + + CS C +E C TC L + + C KC H T LLP+ KS+ M L A++CIE H+V++V R ++ Q W FFDSM+ + +S + +P V C +S +LSL
Sbjct: 336 GVVRWLGEEIDDEGDRIVRSAIVQLDEDVPTAWRRSHDASSYTGSPVVGGVLVPIQSLKHNHSGSSSNGASVVQTSTYPTSQTYNNISRRTEDFGSMDSGVEKQKCGIAKDMQQLVGRQKGIQGYCNSCYLDATLYAMFVQTTCFDFLLEKSIKGSET---AQQFQKILAHEIVFPLRKVHYVRADHVMKLRKLLAELMPHVTGLTNEEKDPEEILGFIFSKVFHAEPFIKLIGQNHAK-DSQYLVPIVVDDWLGGAATSQHLLERHMRSAQVTFAKAPPVLIMQLPRYGQ-QKVFDKILPLETIDITPFVAGAVPACSKCQACSEVYCPTCFLTRRVFYSEVIFC--RKCFH--HTHLLPEIEDHKSRDLYPPGKPQKKPHSHKMVLSAVLCIETSHYVAYV----RTSSNQ----------------WVFFDSMADREGLSDGFNVPVVRECGNMSDWLSL 769
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Celegans
Match: cyld-1 (CYLinDromatosis (Human disease gene) homolog [Source:UniProtKB/TrEMBL;Acc:H2L265]) HSP 1 Score: 131.339 bits (329), Expect = 2.207e-30 Identity = 124/463 (26.78%), Postives = 198/463 (42.76%), Query Frame = 2
Query: 4496 GTVKWTGV---DENDCYFFG--LELDDRINIGTDGTFGGQRLFTCQNGHGVLAPL----NNVASDTRFTAKVVSPENVKKSETSDQIV-----------------CGLNSSV--IAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENV-STLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTC-LGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVF--------------MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXX-XXXYAIPRVSRCECVSKFLSL 5749
G V+W G DE D ++LD+ + + GVL P+ +N + + A VV S+T + I CG+ + + G KGIQG NSCY D+ L+A+FV++ D+L+ I E ++F++I+A IV+PLRK +V H ++R ++ + + +E D E + + SK+ E + +I N K +S ++ + D TS+ +L+ M + F + P LIMQ PR + + LPL I+I+ + + CS C +E C TC L + + C KC H T LLP+ KS+ M L A++CIE H+V++V R ++ Q W FFDSM+ + S + +P V C +S +LSL
Sbjct: 394 GVVRWLGEEIDDEGDRIVRSAIVQLDEDVPTAWRRSHDASSYTGSPVVGGVLVPIQSLKHNHSGSSSNGASVVQTSTYPTSQTYNNISRRTEDFGSMDSGVEKQKCGIAKDMQQLVGRQKGIQGYCNSCYLDATLYAMFVQTTCFDFLLEKSIKGSET---AQQFQKILAHEIVFPLRKVHYVRADHVMKLRKLLAELMPHVTGLTNEEKDPEEILGFIFSKVFHAEPFIKLIGQNHAK-DSQYLVPIVVDDWLGGAATSQHLLERHMRSAQVTFAKAPPVLIMQLPRYGQ-QKVFDKILPLETIDITPFVAGAVPACSKCQACSEVYCPTCFLTRRVFYSEVIFC--RKCFH--HTHLLPEIEDHKSRDLYPPGKPQKKPHSHKMVLSAVLCIETSHYVAYV----RTSSNQ----------------WVFFDSMADREGLSDGFNVPVVRECGNMSDWLSL 827
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Celegans
Match: cyld-1 (CYLinDromatosis (Human disease gene) homolog [Source:UniProtKB/TrEMBL;Acc:H2L265]) HSP 1 Score: 131.339 bits (329), Expect = 3.705e-30 Identity = 124/463 (26.78%), Postives = 198/463 (42.76%), Query Frame = 2
Query: 4496 GTVKWTGV---DENDCYFFG--LELDDRINIGTDGTFGGQRLFTCQNGHGVLAPL----NNVASDTRFTAKVVSPENVKKSETSDQIV-----------------CGLNSSV--IAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENV-STLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTC-LGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVF--------------MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXX-XXXYAIPRVSRCECVSKFLSL 5749
G V+W G DE D ++LD+ + + GVL P+ +N + + A VV S+T + I CG+ + + G KGIQG NSCY D+ L+A+FV++ D+L+ I E ++F++I+A IV+PLRK +V H ++R ++ + + +E D E + + SK+ E + +I N K +S ++ + D TS+ +L+ M + F + P LIMQ PR + + LPL I+I+ + + CS C +E C TC L + + C KC H T LLP+ KS+ M L A++CIE H+V++V R ++ Q W FFDSM+ + S + +P V C +S +LSL
Sbjct: 646 GVVRWLGEEIDDEGDRIVRSAIVQLDEDVPTAWRRSHDASSYTGSPVVGGVLVPIQSLKHNHSGSSSNGASVVQTSTYPTSQTYNNISRRTEDFGSMDSGVEKQKCGIAKDMQQLVGRQKGIQGYCNSCYLDATLYAMFVQTTCFDFLLEKSIKGSET---AQQFQKILAHEIVFPLRKVHYVRADHVMKLRKLLAELMPHVTGLTNEEKDPEEILGFIFSKVFHAEPFIKLIGQNHAK-DSQYLVPIVVDDWLGGAATSQHLLERHMRSAQVTFAKAPPVLIMQLPRYGQ-QKVFDKILPLETIDITPFVAGAVPACSKCQACSEVYCPTCFLTRRVFYSEVIFC--RKCFH--HTHLLPEIEDHKSRDLYPPGKPQKKPHSHKMVLSAVLCIETSHYVAYV----RTSSNQ----------------WVFFDSMADREGLSDGFNVPVVRECGNMSDWLSL 1079
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Fly
Match: CYLD (gene:FBgn0032210 transcript:FBtr0080070) HSP 1 Score: 183.341 bits (464), Expect = 1.291e-47 Identity = 137/494 (27.73%), Postives = 225/494 (45.55%), Query Frame = 2
Query: 4301 GTFWRRQ------IVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFK-------------EIVINSAVKYYFLTATGY-QDLFGTVKWTGVDEND--CYFFGLELDDRIN----IGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRF-------TAKVVSPENVKKSETSD-----------QIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---ELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKV----------------------FMELQAIICIEKCHFVSFVK 5575
GT W ++ I+N++ K + SV+ + K ++K PEE F E+ I S V+ ++ G +DL+G V+W G+ G+E++D N + +DG G RLFTC +G + P N +D RF +A VS + KK +D QI + I G KGIQG+ NSCY D+ LF++F + V D ++ Q+ + E ++++ IV PLRKN FV ++R ++ + + +++ E +++LLS++ E L + +S F QLF+ D+K+ + +++ + S +DI E+P+C I+Q PR K Y LP ++++ I N + CS+C AE++C+ C G + CT C P C K +K + V +MEL A++CIE H+V+FVK
Sbjct: 78 GTNWPKRAGPAAMILNNKSKTDPSNSVDLILKPASPILKIEPEEPLRFTIADYQPLIEIPGTELAIGSLVE---VSNPGVCEDLYGVVRWIGIPPGPQKNVLVGIEVEDESNLKNVVASDGRHNGVRLFTCHDGRAIFVPANRCTADRRFADVDNSISANRVSSNHAKKFGVADCPAIYGSIPPLQIHNSDELASICGKFKGIQGHHNSCYLDATLFSMFTFTSVFDSILYRRPGPQDIRNYS-EVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKDPEEFLNSLLSQIMRVEPFLKL----SSGQDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDCFGSLQAGSGLECTAFC-------PKCLKTFHSHIKRTNHVSKKIYSPKEFKIMAEHMVVPRLYMELFAVVCIETSHYVAFVK 556
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Fly
Match: CYLD (gene:FBgn0032210 transcript:FBtr0080071) HSP 1 Score: 183.341 bits (464), Expect = 1.291e-47 Identity = 137/494 (27.73%), Postives = 225/494 (45.55%), Query Frame = 2
Query: 4301 GTFWRRQ------IVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFK-------------EIVINSAVKYYFLTATGY-QDLFGTVKWTGVDEND--CYFFGLELDDRIN----IGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRF-------TAKVVSPENVKKSETSD-----------QIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---ELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKV----------------------FMELQAIICIEKCHFVSFVK 5575
GT W ++ I+N++ K + SV+ + K ++K PEE F E+ I S V+ ++ G +DL+G V+W G+ G+E++D N + +DG G RLFTC +G + P N +D RF +A VS + KK +D QI + I G KGIQG+ NSCY D+ LF++F + V D ++ Q+ + E ++++ IV PLRKN FV ++R ++ + + +++ E +++LLS++ E L + +S F QLF+ D+K+ + +++ + S +DI E+P+C I+Q PR K Y LP ++++ I N + CS+C AE++C+ C G + CT C P C K +K + V +MEL A++CIE H+V+FVK
Sbjct: 78 GTNWPKRAGPAAMILNNKSKTDPSNSVDLILKPASPILKIEPEEPLRFTIADYQPLIEIPGTELAIGSLVE---VSNPGVCEDLYGVVRWIGIPPGPQKNVLVGIEVEDESNLKNVVASDGRHNGVRLFTCHDGRAIFVPANRCTADRRFADVDNSISANRVSSNHAKKFGVADCPAIYGSIPPLQIHNSDELASICGKFKGIQGHHNSCYLDATLFSMFTFTSVFDSILYRRPGPQDIRNYS-EVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKDPEEFLNSLLSQIMRVEPFLKL----SSGQDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDCFGSLQAGSGLECTAFC-------PKCLKTFHSHIKRTNHVSKKIYSPKEFKIMAEHMVVPRLYMELFAVVCIETSHYVAFVK 556
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Fly
Match: CYLD (gene:FBgn0032210 transcript:FBtr0080072) HSP 1 Score: 176.407 bits (446), Expect = 6.432e-46 Identity = 118/413 (28.57%), Postives = 192/413 (46.49%), Query Frame = 2
Query: 4484 QDLFGTVKWTGVDEND--CYFFGLELDDRIN----IGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRF-------TAKVVSPENVKKSETSD-----------QIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---ELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKV----------------------FMELQAIICIEKCHFVSFVK 5575
+DL+G V+W G+ G+E++D N + +DG G RLFTC +G + P N +D RF +A VS + KK +D QI + I G KGIQG+ NSCY D+ LF++F + V D ++ Q+ + E ++++ IV PLRKN FV ++R ++ + + +++ E +++LLS++ E L + +S F QLF+ D+K+ + +++ + S +DI E+P+C I+Q PR K Y LP ++++ I N + CS+C AE++C+ C G + CT C P C K +K + V +MEL A++CIE H+V+FVK
Sbjct: 68 EDLYGVVRWIGIPPGPQKNVLVGIEVEDESNLKNVVASDGRHNGVRLFTCHDGRAIFVPANRCTADRRFADVDNSISANRVSSNHAKKFGVADCPAIYGSIPPLQIHNSDELASICGKFKGIQGHHNSCYLDATLFSMFTFTSVFDSILYRRPGPQDIRNYS-EVQKVLRDEIVNPLRKNVFVRSDRVMKLRELLDQLSSVSGLTCEEKDPEEFLNSLLSQIMRVEPFLKL----SSGQDSYFYQLFVEKDEKLTLPSVQQLFEQSFHSSDIKLKEVPSCFIIQMPRFGKNYKMYPRILPSQVLDVTDIIENSPRQCSLCGKLAEYECRDCFGSLQAGSGLECTAFC-------PKCLKTFHSHIKRTNHVSKKIYSPKEFKIMAEHMVVPRLYMELFAVVCIETSHYVAFVK 468
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Zebrafish
Match: cylda (cylindromatosis (turban tumor syndrome), a [Source:ZFIN;Acc:ZDB-GENE-061108-2]) HSP 1 Score: 169.088 bits (427), Expect = 7.533e-42 Identity = 135/492 (27.44%), Postives = 225/492 (45.73%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTV---KSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF + SP +++ +E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + KE +E++ IV PLR +G+V ++R +++K A +++ E ++ L + + LL + + F Q+F+ KV TS+++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D DIT + C+ HP + K L ++V S MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VSRC V ++L ++ +++ N + +L D+ + +Y + + + Y
Sbjct: 440 LCGVIRWVGLPPGLQESLAGLELEEECVGCTDGTFKGIRYFTCPPKKALFVKLKCCRPDSRFPSLHHSPNPIERCNSIAFGGYLSEVVNENTPPRTENDGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPRSKTDVE-YYKETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYED-YDITPGKIKQFCEKCNTQVHLHPRRKIHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYG------------------SADSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 911
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Zebrafish
Match: cylda (cylindromatosis (turban tumor syndrome), a [Source:ZFIN;Acc:ZDB-GENE-061108-2]) HSP 1 Score: 169.088 bits (427), Expect = 9.359e-42 Identity = 135/492 (27.44%), Postives = 225/492 (45.73%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTV---KSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF + SP +++ +E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + KE +E++ IV PLR +G+V ++R +++K A +++ E ++ L + + LL + + F Q+F+ KV TS+++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D DIT + C+ HP + K L ++V S MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VSRC V ++L ++ +++ N + +L D+ + +Y + + + Y
Sbjct: 479 LCGVIRWVGLPPGLQESLAGLELEEECVGCTDGTFKGIRYFTCPPKKALFVKLKCCRPDSRFPSLHHSPNPIERCNSIAFGGYLSEVVNENTPPRTENDGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPRSKTDVE-YYKETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYED-YDITPGKIKQFCEKCNTQVHLHPRRKIHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYG------------------SADSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 950
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Zebrafish
Match: cylda (cylindromatosis (turban tumor syndrome), a [Source:ZFIN;Acc:ZDB-GENE-061108-2]) HSP 1 Score: 169.088 bits (427), Expect = 9.359e-42 Identity = 135/492 (27.44%), Postives = 225/492 (45.73%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTV---KSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF + SP +++ +E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + KE +E++ IV PLR +G+V ++R +++K A +++ E ++ L + + LL + + F Q+F+ KV TS+++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D DIT + C+ HP + K L ++V S MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VSRC V ++L ++ +++ N + +L D+ + +Y + + + Y
Sbjct: 479 LCGVIRWVGLPPGLQESLAGLELEEECVGCTDGTFKGIRYFTCPPKKALFVKLKCCRPDSRFPSLHHSPNPIERCNSIAFGGYLSEVVNENTPPRTENDGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPRSKTDVE-YYKETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLRLRSAGQKVQDCYFYQIFMDKKDKVMVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLDDTPRECRICGGLALYECRECYED-YDITPGKIKQFCEKCNTQVHLHPRRKIHRYVKLSVPKELHESVWRQGSYPHQQMELFAVLCIETSHYVAFVKYG------------------SADSAWLFFDSMADRDGGQNGFNIPQVSRCPEVGEYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 950
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Zebrafish
Match: cyldb (cylindromatosis (turban tumor syndrome), b [Source:ZFIN;Acc:ZDB-GENE-100208-1]) HSP 1 Score: 166.392 bits (420), Expect = 1.251e-41 Identity = 140/511 (27.40%), Postives = 230/511 (45.01%), Query Frame = 2
Query: 4397 KTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDEN--DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRF------TAKVVSPENVKKSETSDQIVCGLNS----SVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMEN-VSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQH--KCQHPACTKLLPDTVKSKSKV---FMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXX--XXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHN 5842
K + E IQ + L+ G ++G ++W GV E +C+ GLELD +DGT G +R FTC+ + PL N D+RF K ++P + E D+ V + S + G KGIQG+ NSCY D+ LF+LF S D + + + AD K I+ IV LR++GFV + + R ++ G K +E D E ++ LL + E LL I + Q+ + ++ + +++L++S V +++ F E+P+CLI+Q PR K + +P E++I+ + + C +C A+++C CL D + TC H + +H LPD + V M+L A++CI H+VSFVK + +W FFDSM+ + + Y+IP + C V FLS SE+++ S + ++ ++ DS + +Y
Sbjct: 210 KDVSESIQALSHYSLEVGSMAEVLSLNGLT-VYGVIRWIGVPEGKKNCWA-GLELDTEATTCSDGTLGTKRYFTCEANKALFVPLTNCKPDSRFLLIPDEMLKPLNPPSATLVEDLDEDVPPVAEQDVLSHLVGRMKGIQGHFNSCYLDATLFSLFTSSVAFDRIFN-----RSADS-KKGISHILRRDIVNCLRRSGFVPAENVMKFR---EQLGCK--SFASEEKDPEEFITLLLQHVLHIEPLLKIRSQGEFPQEAYTHQIIVEKNQVAAVPSVQQLLEMSFVTSNLKFEEIPSCLIVQMPRFGKKFKMFPKIIPSTELDITDVLHCSPRECFLCGHLAKYECVQCLMDRKLQPGKIKQYCSTCNTQVHNHPTRQEHTPQKLTLPDCPAEDAPVQRHPMQLFAVLCINTSHYVSFVKYG------------------PDPRSWIFFDSMADRCGDDNKGYSIPVIRSCPEVGDFLSQSEEEISSADLSQCSEAVRRLMVDSYMCLYQT 689
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Zebrafish
Match: cyldb (cylindromatosis (turban tumor syndrome), b [Source:ZFIN;Acc:ZDB-GENE-100208-1]) HSP 1 Score: 154.066 bits (388), Expect = 5.651e-39 Identity = 120/420 (28.57%), Postives = 193/420 (45.95%), Query Frame = 2
Query: 4397 KTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDEN--DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRF------TAKVVSPENVKKSETSDQIVCGLNS----SVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMEN-VSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQH--KCQHPACTKLLPDTVKSKSKV---FMELQAIICIEKCHFVSFVK 5575
K + E IQ + L+ G ++G ++W GV E +C+ GLELD +DGT G +R FTC+ + PL N D+RF K ++P + E D+ V + S + G KGIQG+ NSCY D+ LF+LF S D + + + AD K I+ IV LR++GFV + + R ++ G K +E D E ++ LL + E LL I + Q+ + ++ + +++L++S V +++ F E+P+CLI+Q PR K + +P E++I+ + + C +C A+++C CL D + TC H + +H LPD + V M+L A++CI H+VSFVK
Sbjct: 36 KDVSESIQALSHYSLEVGSMAEVLSLNGLT-VYGVIRWIGVPEGKKNCWA-GLELDTEATTCSDGTLGTKRYFTCEANKALFVPLTNCKPDSRFLLIPDEMLKPLNPPSATLVEDLDEDVPPVAEQDVLSHLVGRMKGIQGHFNSCYLDATLFSLFTSSVAFDRIFN-----RSADS-KKGISHILRRDIVNCLRRSGFVPAENVMKFR---EQLGCK--SFASEEKDPEEFITLLLQHVLHIEPLLKIRSQGEFPQEAYTHQIIVEKNQVAAVPSVQQLLEMSFVTSNLKFEEIPSCLIVQMPRFGKKFKMFPKIIPSTELDITDVLHCSPRECFLCGHLAKYECVQCLMDRKLQPGKIKQYCSTCNTQVHNHPTRQEHTPQKLTLPDCPAEDAPVQRHPMQLFAVLCINTSHYVSFVK 442
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227]) HSP 1 Score: 158.303 bits (399), Expect = 2.296e-38 Identity = 134/498 (26.91%), Postives = 224/498 (44.98%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDN----------------KGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDIT-------CTFLCSQ---------HKCQHPACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W GV+E GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G+ KGIQG+ NSCY DS LF LF S VLD L+ P E+ E + ++ IV PLR G+V ++R +++K A +++ E ++ L + + LL I + F Q+F+ ++ V T +++L+ S + + + F E P+CLI+Q PR K + P ++ I+ + + + C IC G A ++C+ C D+ DIT C +Q HK + K LPD + M+L A++CIE H+V+FVK +++ +W FFDSM+ + + IP+V+ C V ++L +S +++ N + +L D+ + +Y + + + Y
Sbjct: 421 FYGVIRWIGQPAGVNE---MLAGLELEDECAGCTDGTFKGTRYFTCAPKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEGNTPPRTEKEGLEVMIGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDSVLLRP--KEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECY-DDPDITAGKIKQFCKICNTQVHLHPKRQHHKFNPVSLPKELPDWDWRHGCIPYQKMDLFAVLCIETSHYVAFVKYG------------------RDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 892
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227]) HSP 1 Score: 158.303 bits (399), Expect = 3.407e-38 Identity = 134/498 (26.91%), Postives = 224/498 (44.98%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDN----------------KGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDIT-------CTFLCSQ---------HKCQHPACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W GV+E GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G+ KGIQG+ NSCY DS LF LF S VLD L+ P E+ E + ++ IV PLR G+V ++R +++K A +++ E ++ L + + LL I + F Q+F+ ++ V T +++L+ S + + + F E P+CLI+Q PR K + P ++ I+ + + + C IC G A ++C+ C D+ DIT C +Q HK + K LPD + M+L A++CIE H+V+FVK +++ +W FFDSM+ + + IP+V+ C V ++L +S +++ N + +L D+ + +Y + + + Y
Sbjct: 503 FYGVIRWIGQPAGVNE---MLAGLELEDECAGCTDGTFKGTRYFTCAPKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEGNTPPRTEKEGLEVMIGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDSVLLRP--KEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECY-DDPDITAGKIKQFCKICNTQVHLHPKRQHHKFNPVSLPKELPDWDWRHGCIPYQKMDLFAVLCIETSHYVAFVKYG------------------RDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 974
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227]) HSP 1 Score: 157.918 bits (398), Expect = 3.557e-38 Identity = 134/498 (26.91%), Postives = 224/498 (44.98%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDN----------------KGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDIT-------CTFLCSQ---------HKCQHPACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W GV+E GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G+ KGIQG+ NSCY DS LF LF S VLD L+ P E+ E + ++ IV PLR G+V ++R +++K A +++ E ++ L + + LL I + F Q+F+ ++ V T +++L+ S + + + F E P+CLI+Q PR K + P ++ I+ + + + C IC G A ++C+ C D+ DIT C +Q HK + K LPD + M+L A++CIE H+V+FVK +++ +W FFDSM+ + + IP+V+ C V ++L +S +++ N + +L D+ + +Y + + + Y
Sbjct: 485 FYGVIRWIGQPAGVNE---MLAGLELEDECAGCTDGTFKGTRYFTCAPKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEGNTPPRTEKEGLEVMIGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDSVLLRP--KEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECY-DDPDITAGKIKQFCKICNTQVHLHPKRQHHKFNPVSLPKELPDWDWRHGCIPYQKMDLFAVLCIETSHYVAFVKYG------------------RDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 956
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227]) HSP 1 Score: 132.494 bits (332), Expect = 1.600e-30 Identity = 107/391 (27.37%), Postives = 183/391 (46.80%), Query Frame = 2
Query: 4751 VIAGDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDIT-------CTFLCSQ---------HKCQHPACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E + ++ IV PLR G+V ++R +++K A +++ E ++ L + + LL I + F Q+F+ ++ V T +++L+ S + + + F E P+CLI+Q PR K + P ++ I+ + + + C IC G A ++C+ C D+ DIT C +Q HK + K LPD + M+L A++CIE H+V+FVK +++ +W FFDSM+ + + IP+V+ C V ++L +S +++ N + +L D+ + +Y + + + Y
Sbjct: 402 VMIGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDSVLLRP--KEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKIRSAGQKVQDCYFYQIFMDKNENVGVPTIQQLLEWSFINSSLKFAEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECY-DDPDITAGKIKQFCKICNTQVHLHPKRQHHKFNPVSLPKELPDWDWRHGCIPYQKMDLFAVLCIETSHYVAFVKYG------------------RDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 771
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Xenopus
Match: tril (TLR4 interactor with leucine-rich repeats [Source:Xenbase;Acc:XB-GENE-6050227]) HSP 1 Score: 132.88 bits (333), Expect = 2.067e-30 Identity = 130/499 (26.05%), Postives = 215/499 (43.09%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDN----------------KGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFM-TSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDIT-------CTFLCSQ---------HKCQHPACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W GV+E GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G+ KGIQG+ NSCY DS LF LF S VLD L+ P E+ E + ++ IV PLR G+V ++R +++K +E S S+ E+ L+I +F + ++ K+ +L +++ N + E P+CLI+Q PR K + P ++ I+ + + + C IC G A ++C+ C D+ DIT C +Q HK + K LPD + M+L A++CIE H+V+FVK +++ +W FFDSM+ + + IP+V+ C V ++L +S +++ N + +L D+ + +Y + + + Y
Sbjct: 502 FYGVIRWIGQPAGVNE---MLAGLELEDECAGCTDGTFKGTRYFTCAPKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEGNTPPRTEKEGLEVMIGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDSVLLRP--KEKTDVEYYSETQALLRTEIVNPLRIYGYVCATKIMKLRKILEK--------------VEAASGFTSEEKDPEEFLNI----------LFHHILRNIESKLSVTDICAGLLWVTL--NIELVCEAPSCLIVQMPRFGKDFKMFNKIFPSLDLNITDLLEDTPRQCRICGGLAMYECRECY-DDPDITAGKIKQFCKICNTQVHLHPKRQHHKFNPVSLPKELPDWDWRHGCIPYQKMDLFAVLCIETSHYVAFVKYG------------------RDDSSWVFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEELHALDSRNIQGCARRLLCDAYMCMYQSPTMSLY 948
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506]) HSP 1 Score: 162.54 bits (410), Expect = 9.716e-40 Identity = 135/496 (27.22%), Postives = 222/496 (44.76%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPIT--KEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD ++ + +E + I E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 480 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVL---LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506]) HSP 1 Score: 162.54 bits (410), Expect = 9.716e-40 Identity = 135/496 (27.22%), Postives = 222/496 (44.76%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPIT--KEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD ++ + +E + I E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 480 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVL---LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506]) HSP 1 Score: 162.54 bits (410), Expect = 9.716e-40 Identity = 135/496 (27.22%), Postives = 222/496 (44.76%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPIT--KEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD ++ + +E + I E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 480 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVL---LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506]) HSP 1 Score: 162.54 bits (410), Expect = 1.089e-39 Identity = 135/496 (27.22%), Postives = 222/496 (44.76%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPIT--KEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD ++ + +E + I E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 483 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVL---LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 954
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Mouse
Match: Cyld (CYLD lysine 63 deubiquitinase [Source:MGI Symbol;Acc:MGI:1921506]) HSP 1 Score: 162.155 bits (409), Expect = 1.387e-39 Identity = 135/496 (27.22%), Postives = 222/496 (44.76%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPIT--KEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD ++ + +E + I E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 483 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVL---LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 954
BLAST of Cylindromatosis (turban tumor syndrome), b vs. UniProt/SwissProt
Match: sp|Q1RMU2|CYLD_BOVIN (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Bos taurus OX=9913 GN=CYLD PE=2 SV=1) HSP 1 Score: 165.236 bits (417), Expect = 1.189e-39 Identity = 137/495 (27.68%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S D + + +L D+ + +Y + + + Y
Sbjct: 481 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGFEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLECSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNAQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLDDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. UniProt/SwissProt
Match: sp|Q9NQC7|CYLD_HUMAN (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Homo sapiens OX=9606 GN=CYLD PE=1 SV=1) HSP 1 Score: 163.31 bits (412), Expect = 4.245e-39 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 484 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955
BLAST of Cylindromatosis (turban tumor syndrome), b vs. UniProt/SwissProt
Match: sp|Q5RED8|CYLD_PONAB (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Pongo abelii OX=9601 GN=CYLD PE=2 SV=1) HSP 1 Score: 163.31 bits (412), Expect = 4.433e-39 Identity = 136/495 (27.47%), Postives = 222/495 (44.85%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G + GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S VLD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + C+ HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 484 FYGVIRWIGQPPGLNEVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSVLDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHHILRVEPLLKIRSAGQKVQDCYFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCNTQVHLHPKRLNHKYNPVSLPKDLPDWDWRHGCIPCQNMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 955
BLAST of Cylindromatosis (turban tumor syndrome), b vs. UniProt/SwissProt
Match: sp|Q80TQ2|CYLD_MOUSE (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Mus musculus OX=10090 GN=Cyld PE=1 SV=2) HSP 1 Score: 162.54 bits (410), Expect = 6.797e-39 Identity = 135/496 (27.22%), Postives = 222/496 (44.76%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPIT--KEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD ++ + +E + I E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 480 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVL---LRPKEKNDIEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHSYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 951
BLAST of Cylindromatosis (turban tumor syndrome), b vs. UniProt/SwissProt
Match: sp|Q66H62|CYLD_RAT (Ubiquitin carboxyl-terminal hydrolase CYLD OS=Rattus norvegicus OX=10116 GN=Cyld PE=1 SV=1) HSP 1 Score: 162.155 bits (409), Expect = 1.033e-38 Identity = 136/495 (27.47%), Postives = 220/495 (44.44%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------------GDNKGIQGNANSCYFDSALFALFVKSDVLD-YLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+G ++W G GLEL+D TDGTF G R FTC + L + D+RF + + P + + + G S V+ G KGIQG+ NSCY DS LF LF S LD L+ P E+ E +E++ IV PLR G+V ++R +++K A +++ E ++ L + E LL I + F Q+F+ ++KV T +++L+ S + +++ F E P+CLI+Q PR K +K P E+ I+ + + + C IC G A ++C+ C D+ DI+ + CS HP + K LPD + MEL A++CIE H+V+FVK K++ W FFDSM+ + + IP+V+ C V ++L +S + + + +L D+ + +Y + + + Y
Sbjct: 481 FYGVIRWIGQPPGLSDVLAGLELEDECAGCTDGTFRGTRYFTCALKKALFVKLKSCRPDSRFAS--LQPVSNQIERCNSLAFGGYLSEVVEENTPPKMEKEGLEIMIGKKKGIQGHYNSCYLDSTLFCLFAFSSALDTVLLRP--KEKNDVEYYSETQELLRTEIVNPLRIYGYVCATKIMKLRKILEKVEAASGFTSEEKDPEEFLNILFHDILRVEPLLKIRSAGQKVQDCNFYQIFMEKNEKVGVPTIQQLLEWSFINSNLKFAEAPSCLIIQMPRFGKDFKLFKKIFPSLELNITDLLEDTPRQCRICGGLAMYECRECY-DDPDISAGKIKQFCKTCSTQVHLHPRRLNHTYHPVSLPKDLPDWDWRHGCIPCQKMELFAVLCIETSHYVAFVKYG------------------KDDSAWLFFDSMADRDGGQNGFNIPQVTPCPEVGEYLKMSLEDLHSLDSRRIQGCARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. TrEMBL
Match: A0A2T7NIT4 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19240 PE=4 SV=1) HSP 1 Score: 198.364 bits (503), Expect = 7.155e-48 Identity = 164/583 (28.13%), Postives = 264/583 (45.28%), Query Frame = 2
Query: 4289 NGSNGTFWRRQIV-----NSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGV--DENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFT--AKVVSPENVKKSETSD--QIVCGLNSSV------IAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQ---EADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMEN-VSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTC---LGDELDI-----TCTFLCSQHK---CQHPACTKLLPDTVKSKSKVF--------------------------MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKEL----KMILEDSCVYIYHNKS 5848
+GS G +W R + N GK+ ++S +P ++V+ S V+ G L+G +KW G D+ + GLE+++ I+ GTDGTF G+RLF+C PLN D RF AK S E ET D +C + + G ++GIQG+ NSCY D+ LF++F + V D+ I NE ++ P + ++++ IV PLR+ +V ++R ++ K G MM +E D E +S LLS++ + LL H ++ F QLFL D+K+ T++ ++++S +Q ++ E+P+CL++Q PR K Y+ +P E++I+ I ++ C +C A F+CK C G L TC + QHK HP + P+ + S++ MEL A++CI+ H+VSFVK + E W FFDSM+ Y IP V +S++ LSED + + D K L + +L D+ + +Y + +
Sbjct: 349 SGSQGAWWTRLRMKSLDRNRDGKQSSSSSTTSSVPPDP--------------DLVVGSMVEVLL---QGKPPLYGVIKWIGTFDDQTNKVIAGLEMEEEISAGTDGTFKGKRLFSCAPHKAFFVPLNKCRKDKRFQGDAKRPSQEEFGTIETPDIDGEICPPDVKTPEDLLPVCGKSRGIQGHHNSCYLDATLFSMFYFTTVFDF----IFNEPPRPDSVPEHQRVQKVLKEGIVNPLRRYNYVRADKVLKLRELLDKLGT-IPGMMGEEKDPEEFLSALLSQVIKADPLL----HLSSGEHTYFYQLFLEKDEKLLLPTTQILVELSFLQGNVKLKEVPSCLMLQMPRFGKDYKMYRRIIPSLELDITDILETGIRECIVCGSLARFECKDCHLIHGQGLSTTAFCATCIKMSHQHKKRQAHHPKELMVPPEFLAKYSQICEESGPICRQNGEPLGTSHDYGLPKEKMELFAVLCIQTSHYVSFVK-----------------CGLGKEAPWVFFDSMADRMGEQGGYNIPEVQHVPELSRW--LSEDNFQSILDVEDDKNLPEHMRRLLCDAYMCMYQSPT 886
BLAST of Cylindromatosis (turban tumor syndrome), b vs. TrEMBL
Match: H3A9I5 (Uncharacterized protein OS=Latimeria chalumnae OX=7897 GN=LOC102365523 PE=3 SV=1) HSP 1 Score: 194.512 bits (493), Expect = 1.548e-46 Identity = 143/502 (28.49%), Postives = 239/502 (47.61%), Query Frame = 2
Query: 4463 FLTATGYQDLFGTVKWTG-VDENDCYFFGLELDDRI-NIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTA------------KVVSPENVKKS--ETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDIT----------CTFLCSQHKCQ--HPACTKLLPDTVK-------SKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
++ G L+G ++W G V GLEL++R+ N+ TDGTF G R F C G+ L N D+RF + K+ EN ++ E + + + G KGIQG+ NSCY D+ LF +F S VLD ++ ++ + D ++ R+++ IV PLRKNG+V +R +++ G + + +E D E L ++ E LL I + +F Q+F+ + V + +++L+ S V +D+ F E P+C I+Q PR K + LP E++I+ + + + CSIC + +C+ C D DIT C+ QH+ + H LLP ++ S MEL A++CIE H+V+FVK + +W FFDSM+ + S + IP+VS C V+++L +S D+++ + ++ +L D+ + +YHN + + Y
Sbjct: 449 YMVEVGRDPLYGMIRWIGEVSGIHEPIAGLELEERLPNVATDGTFRGVRYFHCDPEKGLFVKLGNCRPDSRFASLHSSSNDISVLDKLALKENASETVEEDTPPEMGKEGGEKMTGWKKGIQGHCNSCYLDATLFCMFAFSSVLDTILLRPQDKNDEDSYSQT-RDLLRTEIVNPLRKNGYVCATKVMALRKILEA-GGQSTGFLTEEKDPEEFLNKLFQVLKVEPLLKIRSATQKPQDCIFYQIFMEKKQSVNIPSVQQLLEWSFVNSDLKFTEAPSCFIVQMPRFGKNFKMFSTILPTLELDITDLLEDTPRECSICQSLSMVECRNCYEDS-DITPGRIKQYCSVCSKQVHQHRNRKSHDPRNLLLPKELQDCNEFPGSIPHQTMELSAVLCIETSHYVAFVKYG------------------PADTDWLFFDSMADRKGGQSGFNIPQVSPCPEVAEYLKMSADELRDLDPKSMQGCVRRLLCDAYMCMYHNPTLSLY 929
BLAST of Cylindromatosis (turban tumor syndrome), b vs. TrEMBL
Match: A0A1S3P2U8 (ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X3 OS=Salmo salar OX=8030 GN=LOC106582893 PE=3 SV=1) HSP 1 Score: 190.274 bits (482), Expect = 3.999e-46 Identity = 143/515 (27.77%), Postives = 239/515 (46.41%), Query Frame = 2
Query: 4406 PEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGV-DENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKS--------ETSDQIVCGLNSS----VIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMEN-VSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQHKCQHPACTKLL--PDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXX--XXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
P E+ E+ N+ + Y G ++W GV EN + G+ELD +N +DGT+GGQ+ FTC+ G + PL + D RF E +K + E +D+ V + S ++ G KGIQG+ NSCY D+ LF+LF S LD + +++ I++ ++ I R LR+ GFV + + N ++ G + +E D E ++ LL ++ + LL + +N ++ Q+ L ++ T +++L IS++ + F E+P+CL++ PR K + + +P E +I+ + N + C +C AE++C CL D + TC H + C + L P V + + V M+L A++CI H+VSFVK +W FFDSM+ + S Y IP + C V FLS SE+++ + S + ++ +L DS +Y+Y + S Y
Sbjct: 233 PFEVGSIVEVTSNTGITVY-----------GVIRWMGVLSENKNDWAGIELDYEVNNCSDGTYGGQQYFTCKEGRALFVPLTKCSPDGRFLCPPSEKETLKATDIPPVIPLEETDENVPPIPESEALSLLVGKMKGIQGHYNSCYLDATLFSLFSSSMTLDSVCHKPAGTEKS--ISRSLKKDIVNR----LRRQGFVP---AESVMNFRKQLGCD--TFVTEEKDPEEFITILLQRVLCMKSLLKLRSNNNTSQDAYTFQIILDKEQVTQTPTVQQLLDISLLSCGLKFEEIPSCLMVHMPRFGKKYKMFPHIIPSTEFDITDLLYNSPRECFLCGRLAEYECPQCLQDRKLQPGRIKQYCTTCKTQVHTHPSRQSHCPRALAVPAEVPADAPVPRHKMQLFAVLCIHTSHYVSFVKYG------------------PGPRSWLFFDSMADRCGDDQSGYNIPEIRACPEVGDFLSQSEEELARADPSQAGEPVRRLLSDSYMYLYQSASMALY 707
BLAST of Cylindromatosis (turban tumor syndrome), b vs. TrEMBL
Match: A0A1S3P2Y0 (ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X4 OS=Salmo salar OX=8030 GN=LOC106582893 PE=3 SV=1) HSP 1 Score: 190.274 bits (482), Expect = 4.913e-46 Identity = 143/515 (27.77%), Postives = 239/515 (46.41%), Query Frame = 2
Query: 4406 PEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGV-DENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKS--------ETSDQIVCGLNSS----VIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMEN-VSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQHKCQHPACTKLL--PDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXX--XXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
P E+ E+ N+ + Y G ++W GV EN + G+ELD +N +DGT+GGQ+ FTC+ G + PL + D RF E +K + E +D+ V + S ++ G KGIQG+ NSCY D+ LF+LF S LD + +++ I++ ++ I R LR+ GFV + + N ++ G + +E D E ++ LL ++ + LL + +N ++ Q+ L ++ T +++L IS++ + F E+P+CL++ PR K + + +P E +I+ + N + C +C AE++C CL D + TC H + C + L P V + + V M+L A++CI H+VSFVK +W FFDSM+ + S Y IP + C V FLS SE+++ + S + ++ +L DS +Y+Y + S Y
Sbjct: 232 PFEVGSIVEVTSNTGITVY-----------GVIRWMGVLSENKNDWAGIELDYEVNNCSDGTYGGQQYFTCKEGRALFVPLTKCSPDGRFLCPPSEKETLKATDIPPVIPLEETDENVPPIPESEALSLLVGKMKGIQGHYNSCYLDATLFSLFSSSMTLDSVCHKPAGTEKS--ISRSLKKDIVNR----LRRQGFVP---AESVMNFRKQLGCD--TFVTEEKDPEEFITILLQRVLCMKSLLKLRSNNNTSQDAYTFQIILDKEQVTQTPTVQQLLDISLLSCGLKFEEIPSCLMVHMPRFGKKYKMFPHIIPSTEFDITDLLYNSPRECFLCGRLAEYECPQCLQDRKLQPGRIKQYCTTCKTQVHTHPSRQSHCPRALAVPAEVPADAPVPRHKMQLFAVLCIHTSHYVSFVKYG------------------PGPRSWLFFDSMADRCGDDQSGYNIPEIRACPEVGDFLSQSEEELARADPSQAGEPVRRLLSDSYMYLYQSASMALY 706
BLAST of Cylindromatosis (turban tumor syndrome), b vs. TrEMBL
Match: A0A1S3P338 (ubiquitin carboxyl-terminal hydrolase CYLD-like isoform X1 OS=Salmo salar OX=8030 GN=LOC106582893 PE=3 SV=1) HSP 1 Score: 189.504 bits (480), Expect = 9.363e-46 Identity = 144/518 (27.80%), Postives = 239/518 (46.14%), Query Frame = 2
Query: 4406 PEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGV-DENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKS--------ETSDQIVCGLNSS----VIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMEN-VSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQHKCQHPACTKLL--PDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-----XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
P E+ E+ N+ + Y G ++W GV EN + G+ELD +N +DGT+GGQ+ FTC+ G + PL + D RF E +K + E +D+ V + S ++ G KGIQG+ NSCY D+ LF+LF S LD + +++ I++ ++ I R LR+ GFV + + N ++ G + +E D E ++ LL ++ + LL + +N ++ Q+ L ++ T +++L IS++ + F E+P+CL++ PR K + + +P E +I+ + N + C +C AE++C CL D + TC H + C + L P V + + V M+L A++CI H+VSFVK +W FFDSM+ S S Y IP + C V FLS SE+++ + S + ++ +L DS +Y+Y + S Y
Sbjct: 233 PFEVGSIVEVTSNTGITVY-----------GVIRWMGVLSENKNDWAGIELDYEVNNCSDGTYGGQQYFTCKEGRALFVPLTKCSPDGRFLCPPSEKETLKATDIPPVIPLEETDENVPPIPESEALSLLVGKMKGIQGHYNSCYLDATLFSLFSSSMTLDSVCHKPAGTEKS--ISRSLKKDIVNR----LRRQGFVP---AESVMNFRKQLGCD--TFVTEEKDPEEFITILLQRVLCMKSLLKLRSNNNTSQDAYTFQIILDKEQVTQTPTVQQLLDISLLSCGLKFEEIPSCLMVHMPRFGKKYKMFPHIIPSTEFDITDLLYNSPRECFLCGRLAEYECPQCLQDRKLQPGRIKQYCTTCKTQVHTHPSRQSHCPRALAVPAEVPADAPVPRHKMQLFAVLCIHTSHYVSFVKYG------------------PGPRSWLFFDSMADRCVPSGDDQSGYNIPEIRACPEVGDFLSQSEEELARADPSQAGEPVRRLLSDSYMYLYQSASMALY 710
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Cavefish
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:103044817]) HSP 1 Score: 164.466 bits (415), Expect = 1.985e-40 Identity = 132/492 (26.83%), Postives = 222/492 (45.12%), Query Frame = 2
Query: 4490 LFGTVKWTGVDENDC-YFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF ++ SP +++ +E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + E +E++ IV PLR +G+V ++R +++K A +++ E ++ L + + LL + + F Q+F+ KV TS+++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D DIT + C+ HP + K L + V + MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VS C V +L ++ +++ N + +L D+ + +Y + + + Y
Sbjct: 442 LCGVIRWVGLPPGLLEPLAGLELEEECVGCTDGTFKGTRYFTCPPKKALFVKLKCCRPDSRFPSQHHSPNPIERCNSIAFGGYLSEVVNENTPPRTENDGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPKSKTDVE-YYLETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDA-DITAGKIKQFCEKCNTQVHLHPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYG------------------AADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 913
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Cavefish
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:103044817]) HSP 1 Score: 164.466 bits (415), Expect = 2.129e-40 Identity = 132/492 (26.83%), Postives = 222/492 (45.12%), Query Frame = 2
Query: 4490 LFGTVKWTGVDENDC-YFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF ++ SP +++ +E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + E +E++ IV PLR +G+V ++R +++K A +++ E ++ L + + LL + + F Q+F+ KV TS+++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D DIT + C+ HP + K L + V + MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VS C V +L ++ +++ N + +L D+ + +Y + + + Y
Sbjct: 481 LCGVIRWVGLPPGLLEPLAGLELEEECVGCTDGTFKGTRYFTCPPKKALFVKLKCCRPDSRFPSQHHSPNPIERCNSIAFGGYLSEVVNENTPPRTENDGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPKSKTDVE-YYLETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDA-DITAGKIKQFCEKCNTQVHLHPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYG------------------AADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Cavefish
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:103044817]) HSP 1 Score: 164.466 bits (415), Expect = 2.129e-40 Identity = 132/492 (26.83%), Postives = 222/492 (45.12%), Query Frame = 2
Query: 4490 LFGTVKWTGVDENDC-YFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKSKVF---MELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF ++ SP +++ +E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + E +E++ IV PLR +G+V ++R +++K A +++ E ++ L + + LL + + F Q+F+ KV TS+++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D DIT + C+ HP + K L + V + MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VS C V +L ++ +++ N + +L D+ + +Y + + + Y
Sbjct: 481 LCGVIRWVGLPPGLLEPLAGLELEEECVGCTDGTFKGTRYFTCPPKKALFVKLKCCRPDSRFPSQHHSPNPIERCNSIAFGGYLSEVVNENTPPRTENDGLEVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPKSKTDVE-YYLETQELLRTEIVNPLRIHGYVCATKIMKLRRILEKVEAASGFTSEEKDPEEFLNILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVLVPTSQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLALYECRECYEDA-DITAGKIKQFCEKCNTQVHLHPRRKTHRYGKLSVPKELQEGVWRQGSFPHQQMELFAVLCIETSHYVAFVKYG------------------AADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVGAYLKMTPEELHALDPKNIQGYARRLLCDAYMCMYQSPTMSLY 952
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Cavefish
Match: cyldl (cylindromatosis (turban tumor syndrome), like [Source:ZFIN;Acc:ZDB-GENE-131127-190]) HSP 1 Score: 153.68 bits (387), Expect = 1.814e-37 Identity = 136/510 (26.67%), Postives = 215/510 (42.16%), Query Frame = 2
Query: 4430 EIVINSAVKYYFLTATGYQDLFGTVKWTG-VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSP-----------ENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQHKCQHP--ACTKLLPDTV----------KSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
EI +NS V+ Y GTV+W G + E GLEL++ + DGTF R F C G+ + + D+RF S +NV Q V + G +GIQG+ NSCY DSALF LF S VLD L+ N+ + K +E + IV PLR GFV+ ++R +Q+ G E E ++ ++ + E L S F Q+F+ + + T +++L+ S + + E+P+CLI+ PR K + +P E++I+ + N + C +C A +C C GD L TC+ H + P T LP+ S + +EL A++CIE H+VSFVK + T +W FFDSM+ + + Y +P+V C V ++L++ ++ + K + D +Y+Y + + Y
Sbjct: 264 EINLNSVVEVDLAKGPTY----GTVRWIGHLPEKTDLMAGLELEEDWGV-NDGTFRNDRYFFCPPKRGIFVKVASCRPDSRFLGDNASDGHFVSAVQDLQDNVPVPPLRSQDV----KDFLIGKQRGIQGHCNSCYMDSALF-LFTCSSVLDSLLYKGTNQND-----KHIQETLRKEIVGPLR-TGFVADRSVMKLRQQLQERGHS-PSYTTDEKPEEFLTLIMQDILSLEPPLKKPLGMKKVETSFFYQIFVDYNNTLVLPTVQQLLEHSFYTSCLRLEEVPSCLILTMPRSGKQFKMFPKIIPSLELDITALLYN-PQQCVLCGQLAHVECTECFGDPVFGNTGFKHLCDTCSAQVHLHPSRRPHKPTTMTLPEGFIRMWGSGGPPHSPPREKLELFAVLCIETSHYVSFVKHGPKAT------------------DWIFFDSMADRIEINGYNVPQVKECPEVGRYLTMPLAELAAQVPREMEGVAKRLFCDGYMYLYQSPNMGLY 737
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Cavefish
Match: ENSAMXT00000022455.2 (pep primary_assembly:Astyanax_mexicanus-2.0:21:17282006:17293930:1 gene:ENSAMXG00000021802.2 transcript:ENSAMXT00000022455.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 147.902 bits (372), Expect = 3.433e-35 Identity = 135/520 (25.96%), Postives = 223/520 (42.88%), Query Frame = 2
Query: 4490 LFGTVKWTG-VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENV-------------KKSETSDQIVCGLNS-SVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLF--------------------LTVDKKVPFMTS----------EEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDI----------TCTFLCSQHK---CQHPACTKLLPDTVKSK---SKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKE-LKMILEDSCVYIYHNKSKTCY 5860
+FG ++W G + G+ELD ++ TDG++ G+R F C G+ L N D+RF A V K+ E + V G ++ V G KGIQG+ NSCY D++LF+LF +D+++ + +K+ +E++ IV PLR+ G+V T +R +++ A +E D E L +L E LL I + QLF +P + + +L+ S + + + F E P+CL + PR K + LP +++I+ + L+ CSIC A ++C C D LDI TC HK P ++ T + ++ ++L A+ CIE H+VSFVK T +W FFDSM+ + + + +P+V C V ++LSLSE ++ + + + LKE ++ +L D+ + +YH + Y
Sbjct: 468 IFGVIRWIGQIAGLSEPVAGIELDQELSAATDGSYLGERHFRCPPNKGLFVKLRNCRRDSRFPAPEAPINQVDRCNSIAFAEWGSKRVEDNTPPVLGPDARQVYEGFKKGIQGHLNSCYLDASLFSLFSCCSSVDWVL--FYPSSDDSHRSKDAQELLRCEIVNPLRRYGYVCASKTMALRKLLEAETTD-AGFTNEEKDPEEFLNKLFQLLRVEPLLKIRSMSQEPQECHIYQLFPPSISSSPSSPLHSPLSPSLSNSLSPIPLSSPAAGLMRVASVQALLESSFIHSGLKFTEAPSCLPLLMPRFGKEFKMFDTILPSLKLDITDLLDETLRQCSICQSVAAWECLQCYED-LDITPGQLKQYCNTCNAQVHAHKKRQTHSPLKVRIPKGTWEGPVHGARQQLDLFAVTCIETSHYVSFVKYGPLQT------------------DWLFFDSMADREGGENGFNVPQVRACPEVGRYLSLSEKELGR-LDTTSLKEPVRRLLCDAYMCLYHCPELSLY 964
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000692.1 (pep scaffold:Pmarinus_7.0:GL491130:1075:4385:-1 gene:ENSPMAG00000000632.1 transcript:ENSPMAT00000000692.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 88.9669 bits (219), Expect = 1.265e-19 Identity = 59/190 (31.05%), Postives = 89/190 (46.84%), Query Frame = 2
Query: 4490 LFGTVKWTGVDEN-DCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTA------------KVVSPENVKKSETSDQIVCGLN---SSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLI-SPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYG 5008
+FG ++W GV D G+EL++ + +DGTF R FTC G G D+RF + ++ N + ++ ++V+ G KGIQG+ NSCY DS LF +F S V D ++ P + D T ++++ IV PLRKNGFVS ++R + K G
Sbjct: 35 VFGVIRWIGVPVGLDETLAGIELEEEMQGCSDGTFKQHRFFTCPTGKGFFIQFKKCRPDSRFMSMPHVGLDPVQRCNSLAFSNYRSERVEGEVPPPSEKEATAVVCGRTKGIQGHYNSCYLDSTLFCMFAFSTVFDGMLHRPQRSSDLKDYNT--VQQLLREDIVNPLRKNGFVSATKVMQLRKQLDKIG 222
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Nematostella
Match: EDO47295 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RMM7]) HSP 1 Score: 155.606 bits (392), Expect = 7.088e-40 Identity = 134/494 (27.13%), Postives = 221/494 (44.74%), Query Frame = 2
Query: 4484 QDLFGTVKWTG--VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIA----------GDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAE-FQCKTCLGDEL-DITCTFLCS---QHKCQHPACT--KLLPDTVKSK-----------SKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKEL----KMILEDSCVYIYHNKSKTCY 5860
Q +G ++W G + + GLEL++ + +DGTF G+R F C G G L D+RF + ++ + C +I G +GIQG+ NSCY DS L+++F + V D L+ + + K ++++ IV PLR+NGFV +R ++ K G+ +++ E ++TLL ++ E LL + H C+ S + Q+ D+ + T + +++ S + D+ E+P+CLI+Q PR Y P ++I+ I N + C +C +A F+CK C +++ I T C + HP T KL P V + + MEL A++CI+ H+V+FVK + + W FFDSM+ + S Y IP V C S++L D++ IG+N EL K + D+ + +Y N Y
Sbjct: 10 QPRYGVIRWIGQLAELKNKLVAGLELEEEQSGCSDGTFKGKRYFECPPGRGFFVLLKYCRKDSRFELDSPMDTPGRSAKNFGSMDCPSIEGIIPPPPSLPEQSTGMMRGIQGHHNSCYLDSTLYSMFAFTTVFDTLLHRERQSSDLEDYDK-VQKVLKEEIVNPLRRNGFVRADRVLRLRRLLDKLGSTSGLTDEEKDPEEFLNTLLHQVLKSESLLQLKSHGRCE-ESNYYQIITEKDEGIKLATVQTLIEQSFMAADLKLAEVPSCLILQMPRFGNKYKMYDIIFPNTTLDITDILDNVPRPCVLCGEQASTFECKECYEEKIFSIGITSFCRDCCKKVHSHPRRTSHKLTPIIVPREYSQYARRDGPLERYTMELFAVVCIQTSHYVAFVKCGQ-----------------GPDAPWCFFDSMADRKGESNGYNIPAVRACPEASRWLLAKPDEI---IGANRRGELPGNMKRLFGDAYMCMYQNFDTAMY 481
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Medaka
Match: cyldb (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101163809]) HSP 1 Score: 164.081 bits (414), Expect = 6.068e-41 Identity = 131/477 (27.46%), Postives = 218/477 (45.70%), Query Frame = 2
Query: 4493 FGTVKWTGVDENDCY-FFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRF---------TAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGD---------ELDITCTFLCSQH--KCQH-PACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXX--XXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKE---LKMILEDSCVYIYHN 5842
+G ++W G+ E + G+ELD ++ +DG +GGQR FTC++ + P++ + D+RF T P N E + + S+ G KGIQG+ NSCY D+ LF+LF S V+D + Q+ P+ R I+ LR+ GFV + + N ++ G +++ + E +S L K+ E LL + + +Q+FL ++ T +++L S + D+ F +P+CLI+Q PR + + +P E++I+ + N + C IC AEF+C CL D + +TC H +C H P + D + M+L A++CI+ H+VSFVK +W FFDSM+ + S Y IP + C + FL SE++ + SN L+ ++ +L DS + +Y +
Sbjct: 250 YGVIRWLGIPEEMTEEWAGIELDYEVDGCSDGKYGGQRFFTCESNKALFLPISKCSPDSRFFCSTEKHKVTEIPPVPLNEDLEEDAPPVPESKALSLFLGRMKGIQGHINSCYLDATLFSLFSSSVVVDRICQKPAEPQQ--PLNCTLRTIVNR-----LRRQGFVP---AECVMNFRKQLGCDTFRTDEKDPE-EFISVLFQKVLCIEPLLKLRSEGETSQGANTLQIFLEKEQLQHIPTVQQLLDTSCMSEDLKFEMVPSCLIIQMPRFGNKYKMFSHIIPSMELDITDLLHNSPRECFICGHLAEFECPQCLPDRKLQPGRIKQYCLTCNTQVHSHPSRCSHFPRAVTVPADADTPVPRHTMQLFAVLCIQTSHYVSFVKYG------------------PEPHSWVFFDSMADRCGDDQSGYNIPEIRACPELGDFLCQSEEEQAR---SNPLQAPELVRRLLCDSYMLLYQS 694
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Medaka
Match: ENSORLT00000011257.2 (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101167576]) HSP 1 Score: 163.696 bits (413), Expect = 3.592e-40 Identity = 139/513 (27.10%), Postives = 226/513 (44.05%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENV-------------KKSETSDQIVCGLNS-SVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLI-SPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLF--------------------LTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------------CSQHKCQHPACTKLLPDTVKSK----SKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L+G ++W +GV E G+ELD ++ GTDG++ G+R F C G+ L N D+RF A V K+ E V G + + G KGIQG+ NSCY D+ LF+LF D+L+ P E+ + + ++ + IV PLR+NG+V T +R +++ A QE D E L +L E LL I + QLF L++ + + + +L+ S + + F E P+CL++ PR K + LP ++I+ + + L+ CSIC AE++C C D DIT L +++ H +P+ S ++ M L A+ CIE H+VSFVK + T +W FFDSM+ + + + IP+V C V ++LSLSE+++ + ++ + ++ +L DS + +YH+ + Y
Sbjct: 426 LYGVIRWIGRISGVPET---VAGIELDQELSAGTDGSYLGERRFRCPANKGLFVKLRNCRRDSRFPAPETPVNQVERCNSIAFAEWGSKRVEEHTPPVDGDEARELYQGWKKGIQGHLNSCYLDATLFSLFSCCSSADWLLFWPSDPEEHRSAV--QAQDQLRCEIVNPLRRNGYVCASKTMALRRMLEAANND-ASFTSQEKDPEEFLNKLFQLLRVEPLLKIRSMSLDPQECHLYQLFPPTHPPSPSSPTSPVESPIPLSLPPSLRVASVQNLLETSFMHTGLKFVEAPSCLLLLMPRFGKDFKMFDAILPTLSLDITDLLDDTLRQCSICQSVAEWECLQCYEDP-DITPGHLKQYCQTCNTQVHSHRNRLSHSPVKIGIPEGPWSGPLICTRRKMSLFAVTCIETSHYVSFVKHGPQPT------------------DWLFFDSMADREGGQNGFNIPQVKACPEVGRYLSLSEEELSRVDPASLRETVRRLLCDSYMCLYHSPELSLY 913
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Medaka
Match: ENSORLT00000045278.1 (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101167576]) HSP 1 Score: 163.696 bits (413), Expect = 3.743e-40 Identity = 139/513 (27.10%), Postives = 226/513 (44.05%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENV-------------KKSETSDQIVCGLNS-SVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLI-SPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLF--------------------LTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------------CSQHKCQHPACTKLLPDTVKSK----SKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L+G ++W +GV E G+ELD ++ GTDG++ G+R F C G+ L N D+RF A V K+ E V G + + G KGIQG+ NSCY D+ LF+LF D+L+ P E+ + + ++ + IV PLR+NG+V T +R +++ A QE D E L +L E LL I + QLF L++ + + + +L+ S + + F E P+CL++ PR K + LP ++I+ + + L+ CSIC AE++C C D DIT L +++ H +P+ S ++ M L A+ CIE H+VSFVK + T +W FFDSM+ + + + IP+V C V ++LSLSE+++ + ++ + ++ +L DS + +YH+ + Y
Sbjct: 455 LYGVIRWIGRISGVPET---VAGIELDQELSAGTDGSYLGERRFRCPANKGLFVKLRNCRRDSRFPAPETPVNQVERCNSIAFAEWGSKRVEEHTPPVDGDEARELYQGWKKGIQGHLNSCYLDATLFSLFSCCSSADWLLFWPSDPEEHRSAV--QAQDQLRCEIVNPLRRNGYVCASKTMALRRMLEAANND-ASFTSQEKDPEEFLNKLFQLLRVEPLLKIRSMSLDPQECHLYQLFPPTHPPSPSSPTSPVESPIPLSLPPSLRVASVQNLLETSFMHTGLKFVEAPSCLLLLMPRFGKDFKMFDAILPTLSLDITDLLDDTLRQCSICQSVAEWECLQCYEDP-DITPGHLKQYCQTCNTQVHSHRNRLSHSPVKIGIPEGPWSGPLICTRRKMSLFAVTCIETSHYVSFVKHGPQPT------------------DWLFFDSMADREGGQNGFNIPQVKACPEVGRYLSLSEEELSRVDPASLRETVRRLLCDSYMCLYHSPELSLY 942
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Medaka
Match: ENSORLT00000041324.1 (ubiquitin carboxyl-terminal hydrolase CYLD [Source:NCBI gene;Acc:101167576]) HSP 1 Score: 163.696 bits (413), Expect = 3.743e-40 Identity = 139/513 (27.10%), Postives = 226/513 (44.05%), Query Frame = 2
Query: 4490 LFGTVKW----TGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENV-------------KKSETSDQIVCGLNS-SVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLI-SPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLF--------------------LTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------------CSQHKCQHPACTKLLPDTVKSK----SKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXX-XXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L+G ++W +GV E G+ELD ++ GTDG++ G+R F C G+ L N D+RF A V K+ E V G + + G KGIQG+ NSCY D+ LF+LF D+L+ P E+ + + ++ + IV PLR+NG+V T +R +++ A QE D E L +L E LL I + QLF L++ + + + +L+ S + + F E P+CL++ PR K + LP ++I+ + + L+ CSIC AE++C C D DIT L +++ H +P+ S ++ M L A+ CIE H+VSFVK + T +W FFDSM+ + + + IP+V C V ++LSLSE+++ + ++ + ++ +L DS + +YH+ + Y
Sbjct: 455 LYGVIRWIGRISGVPET---VAGIELDQELSAGTDGSYLGERRFRCPANKGLFVKLRNCRRDSRFPAPETPVNQVERCNSIAFAEWGSKRVEEHTPPVDGDEARELYQGWKKGIQGHLNSCYLDATLFSLFSCCSSADWLLFWPSDPEEHRSAV--QAQDQLRCEIVNPLRRNGYVCASKTMALRRMLEAANND-ASFTSQEKDPEEFLNKLFQLLRVEPLLKIRSMSLDPQECHLYQLFPPTHPPSPSSPTSPVESPIPLSLPPSLRVASVQNLLETSFMHTGLKFVEAPSCLLLLMPRFGKDFKMFDAILPTLSLDITDLLDDTLRQCSICQSVAEWECLQCYEDP-DITPGHLKQYCQTCNTQVHSHRNRLSHSPVKIGIPEGPWSGPLICTRRKMSLFAVTCIETSHYVSFVKHGPQPT------------------DWLFFDSMADREGGQNGFNIPQVKACPEVGRYLSLSEEELSRVDPASLRETVRRLLCDSYMCLYHSPELSLY 942
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Medaka
Match: cylda (CYLD lysine 63 deubiquitinase [Source:NCBI gene;Acc:101156964]) HSP 1 Score: 162.925 bits (411), Expect = 5.585e-40 Identity = 130/492 (26.42%), Postives = 221/492 (44.92%), Query Frame = 2
Query: 4490 LFGTVKWTGVDENDC-YFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKK--------------SETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFL------CSQHKCQHP----------ACTKLLPDTVKSKS---KVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXX-XYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
L G ++W G+ GLEL++ TDGTF G R FTC + L D+RF + SP +++ E + V+ G KGIQG+ NSCY DS LF LF S VLD ++ ++ + + +E +E++ IV PLR +G+V ++R +++K A +++ E + L + + LL + + F Q+F+ KV T +++L+ S + +D+ F E P+CLI+Q PR K + P E++I+ + + + C IC G A ++C+ C D+ DIT + C+ HP + K L + + + MEL A++CIE H+V+FVK + W FFDSM+ + + IP+VS C V +L +S +++ + + + +L D+ + +Y + + + Y
Sbjct: 446 LCGVIRWVGLPPGLLEPLAGLELEEECPGCTDGTFKGTRYFTCPPKKALFVKLKCCRPDSRFPSLHHSPNPIERCNSIAFGGYLSEVVHENTPPRTENDGLDVMVGKKKGIQGHYNSCYLDSTLFCLFSFSSVLDTVLLRPQSKTDVE-YYRETQELLRTEIVNPLRIHGYVCATKVMKLRRILEKVEAASGFTSEEKDPEEFLIILFHHILRVDPLLKLRSAGQKVQDCYFYQIFMDKKDKVGVPTIQQLLEWSFINSDLKFAEAPSCLIIQMPRFGKDFKMFNKIFPSLELDITDLLEDTPRECRICGGLAFYECRDCY-DDGDITAGKIKQFCEKCNTQVHLHPKRKAHRHGKLSVPKELQEGTGRQGGFPRQRMELFAVLCIETSHYVAFVKYG------------------TADSAWLFFDSMADRDGGQNGFNIPQVSPCPEVETYLKMSPEELHTLDPKSIQGQARRLLCDAYMCMYQSPTMSLY 917
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Planmine SMEST
Match: SMESG000007087.1 (SMESG000007087.1) HSP 1 Score: 2894.38 bits (7502), Expect = 0.000e+0 Identity = 1442/1485 (97.10%), Postives = 1453/1485 (97.85%), Query Frame = 2
Query: 263 MHSDKSEDNSIKAVSNIDRQNSATSRTSNDSRDYMANKSVLPTIYCNKLGMDVIKPGAIDQIGKPKGASMNKYIAIQGKTKSFVKLFWKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSKDIKVNSQVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMPIDFIKDIFVEKNQKEFSRGSVRTDDIYHVGQFVKILPFDLFGQIECFHVVYEEMFVQIQLTKDQIKRLPFHQRIDRAAGNAIYSTVILLKDSIAKCSENLEFFNESSLINKECIEYRIPRPMETFRTGDLIKAGKTGNVKYFIVNNRFIINGISCLSVMESILGEAEEYLPESEAMKVDNSELEMKYFQGVFIDPKSIRSFEKCEINDFCIGNRVEFMSMDRKSSYNGRIKSTGIANKTIPSCVVQMPPSEPIVNRSLLQYTLNENLEFKILSGTANDFLFLIRANLLRKSELPETVNGIPVIDPEFIRIIEGVAVEPGKFIVFTCNNQRHSVQLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHVKEINLNVVDPFNVREIENGRQINKLTCYKSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKCV-XXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSE 4714
MHSDKSEDNSIKAVSNIDRQNSATSRTSNDSRDYMANKSVLPTI C+KLG+DVIKPGAIDQIGK KGA MNKYIAIQGKTKSFVKL WKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSKDIKVNSQVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRIL I+GRIRFI LECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMPID IKDIFVEKNQKEFSRGSVRTDDIYHVGQFVKILPFDLFGQIECFHVVYEEMFVQIQLTKDQIKRLPFHQRIDRAAGNAIYSTVILLKDSIAKCSENLEFFNESSLINKECIEYRIPRPMETFRTGDLIKAGKTGNVKYFIVNNRFIINGISCLSVMESILGEAEEYLPESEA+KVDNSEL+MKYFQGVFIDPKSIRSFEKCEINDFCIGNRVEFMSMDRKSSY GRIKSTGIANKTIPSCVVQMPPSEPIVNRSLLQYTLNENLEFKILSGTANDFLFLIRANLLRKSELPETVNGIPVIDPEFIRIIEGVAVEPGKFIVFTCNNQRHSVQLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSN+KAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKI LFRSV KRGALFKSEEFI SKSELKHVKEINLNVVDPFNVREIENGRQINKLTCYKSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFS FRMFTCE GKGVLMLAENIFHDKE EKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINLNSPNGRNRDFIGEVKWTGRINDEKCV +EEEMEHGMDGMIGKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFV VKQ NPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRR+IVNSRGKRVIATSVNHVYKYEPY+ K IPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDD I+IGTDGTFGGQRLFTCQNGHGVLAPLN VASDTRFTAK E +E
Sbjct: 1 MHSDKSEDNSIKAVSNIDRQNSATSRTSNDSRDYMANKSVLPTICCDKLGLDVIKPGAIDQIGKLKGAQMNKYIAIQGKTKSFVKLQWKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSKDIKVNSQVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILNIDGRIRFISLECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMPIDLIKDIFVEKNQKEFSRGSVRTDDIYHVGQFVKILPFDLFGQIECFHVVYEEMFVQIQLTKDQIKRLPFHQRIDRAAGNAIYSTVILLKDSIAKCSENLEFFNESSLINKECIEYRIPRPMETFRTGDLIKAGKTGNVKYFIVNNRFIINGISCLSVMESILGEAEEYLPESEAIKVDNSELKMKYFQGVFIDPKSIRSFEKCEINDFCIGNRVEFMSMDRKSSYKGRIKSTGIANKTIPSCVVQMPPSEPIVNRSLLQYTLNENLEFKILSGTANDFLFLIRANLLRKSELPETVNGIPVIDPEFIRIIEGVAVEPGKFIVFTCNNQRHSVQLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNKKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIPLFRSVTKRGALFKSEEFINSKSELKHVKEINLNVVDPFNVREIENGRQINKLTCYKSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSCFRMFTCESGKGVLMLAENIFHDKEREKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINLNSPNGRNRDFIGEVKWTGRINDEKCVGLDMVEEEMEHGMDGMIGKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVFVKQENPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRRIVNSRGKRVIATSVNHVYKYEPYLSKAIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDNIDIGTDGTFGGQRLFTCQNGHGVLAPLNTVASDTRFTAKETQHEEFLSAE 1485
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Planmine SMEST
Match: SMESG000056847.1 (SMESG000056847.1) HSP 1 Score: 1547.72 bits (4006), Expect = 0.000e+0 Identity = 803/879 (91.35%), Postives = 832/879 (94.65%), Query Frame = 2
Query: 3227 KWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKG-DTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKCVXXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
KW G+VN +G E++ +E GTDG F +F+ +RG L +EE I S AH KITTL +SGWLWKG DTYFINPDCICCTESTE LQ+HPDLRIKSRIKVPNKENK IGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKIN N PNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGM+GMIGKS+ F+CMEKHGLVALLSDVELSENAENPQ+LDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSIS+SYAIPRVS+ S+FL+ S+++MK+ I D ++K I++DS ++IYHNKSKTCY
Sbjct: 296 KWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIIS----AHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSISNSYAIPRVSKAIKESEFLNSSKEKMKESIELYDSGDIKRIIKDSYIFIYHNKSKTCY 1170 HSP 2 Score: 249.595 bits (636), Expect = 7.807e-67 Identity = 155/355 (43.66%), Postives = 204/355 (57.46%), Query Frame = 2
Query: 2789 MKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHVKEINLN------------VVDPFNVREIENGRQINKLTCYKSKGAIKILN---------IKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINK 3787
++GHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIIS H+K L ++P + E+ + + + K IK+ N +W G++NG+ +G + V+ GT+G F +F C +GVL+ E + E+ I + Y I+P C E+ + K IK PN N+ G +W G IN ++ +G+ M+ +++ G NG+ + F C G++ L ++ + +E PQ + ++ NK
Sbjct: 248 VEGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIIS----AHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIA----DKIVDINKIYSISP---CEGENGIGIGK----PIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNK 586 HSP 3 Score: 230.72 bits (587), Expect = 6.026e-61 Identity = 138/383 (36.03%), Postives = 211/383 (55.09%), Query Frame = 2
Query: 524 WKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLI-----LINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSK--DIKVNSQVFC---QQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPL-----ECVENAKLHFIFDKIVDTGKIFYVD-CE-EDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMP 1621
W G +N++ +G E+ E +GT+G F + +LF + RG L +I+ +K + D + + ICC E + L + D+++ S++ + GG C+W+GLING+ +GI D + R+ EG + L E+ K FI DKIVD KI+ + CE E+ +G IN +G+++ FIGE+KW G+IN+EKCVGLDME+E E GM+G+I + RF+CMEKHGL+ +LS+V L + N +L SG+I P+K++R +E + + + IK + V VK N + LKG L+W G MN + VC ++L Q+HENG+NG FWR ++ R K IAT ++ P
Sbjct: 297 WSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISAHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEP 679 HSP 4 Score: 94.3597 bits (233), Expect = 6.839e-19 Identity = 131/506 (25.89%), Postives = 212/506 (41.90%), Query Frame = 2
Query: 2627 KWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGA----------IDENSICCTVEKNITKFQANCKLKN-IKSNRK------AIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHV----KEINLNVVDPFNVREIENGRQINK-----LTCYKSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSR----IKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKC--VXXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDV 4045
KW GL++ +G N GT+G F + +LF K G L SE + H I RD I+ + ICCT + + + ++K+ IK K +W GL+N E +G+ M+ + KGT+G F ++F +G L +E K K K +++N + + E ENG I K + I +KW G +N E CVG ++ +E G +G G F+C + G++ L+ E + +++ + +SG I P+ + S + D IK +K N E K + G WIG +N I +D D + G+NG F + R GK V+ + N + E + I ++I +I S + G +D G VKWTG +++ C GL++++ + G DG G R+F C HG++A L++V
Sbjct: 296 KWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFK----SEEFIISAHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDV-KGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLV----ALLSDVELSENAENPQVLDSG--------MIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELK-LKGKLRWIGWMNKLLVCVIELDQDHENGSNGTF-WRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGY-------------QDLFGTVKWTG-VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNV 768 HSP 5 Score: 77.7962 bits (190), Expect = 7.641e-14 Identity = 76/281 (27.05%), Postives = 118/281 (41.99%), Query Frame = 2
Query: 2621 QLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWK-------------WSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKR------GALFKSEEFIISK--SELKHVKEINLNVVDPFNVREIENGRQINKLTCYKSKGAIKILNIKWRGI-VNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTA 3397
++KW G I+ + C+G + G NG G+ + F C +KHG++ L+ V E E + + G I N E+ K+ + KNIK N I K W G +N + V +E+++ E G++G F + Q+ S KR ++K E ++I E++ KEI +N + T Y+ +KW G+ N G EL + GTDGTFG + +F C GVL P + TA
Sbjct: 515 EVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDV-ELSENAENPQV--LDSGMIAPNKFIRFQEERSKKYLDD---KNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFL---------TATGYQDLFG----TVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTA 776 HSP 6 Score: 70.0922 bits (170), Expect = 1.821e-11 Identity = 75/330 (22.73%), Postives = 146/330 (44.24%), Query Frame = 2
Query: 701 HLPL--ADNDELTANNICCFEPLDKLSKDI-KVNSQVFCQQLKAGGKC--KWMGLINGKGYVGIEFDEIHRRAERFN----ELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKI------FYVD-----CEEDRDYLGNFAAINLTTR----DGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQ-ANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPS 1615
H P+ + + N+ICC + K+I K + + +K+ K KW GL+N +G+E +E + N +L R + G + F E + +A H + D+G + ++++ C E + L + + +R + ++K G +WIG IN ++ +G+ M+++ + G +GI + F C G++ + N+ K + I++ +K G+ I I K +N NG+ + G +KW G +N+ + + +E E+G NG +++ FEC +K + L ++ S
Sbjct: 251 HKPIKWTRDGAIDENSICC-----TVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGAL-FKSEEFIISA--HLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIG---IGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELS 568 HSP 7 Score: 64.6994 bits (156), Expect = 7.609e-10 Identity = 88/381 (23.10%), Postives = 164/381 (43.04%), Query Frame = 2
Query: 524 WKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLP--LADNDELTANNICCFEPLDKLSKDIKVN-SQVFCQQLKAGGKCKWMGLINGKGYVGIEFDE--------IHRRAERFNELSRILKIEGRIRFIP-LECVENAKLHFIFDK-IVDTGKIFYVDCEEDRDYLGN----FAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIIN-PDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGL-MNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLS 1609
W G IN LG + +GT G F +++FTC G+GVL+L + ES E+ + + D +++ + + C E + K IK+N + + G+ KW G IN + VG++ +E + +++RF + + G + + +E ENA+ + D ++ K E + YL + + + + G+L+WIG +N ++++ + E G +G + + K + T +++V YKY+ P I P++ KE + +K + G +L GT+KW G+ N+ ++L GT+G F RLF C++ + N++
Sbjct: 412 WIGLINGQEALGITMDND-VKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKES-EKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEK----HGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHV--YKYE------PYVIKTIPEEIQIFKEIVINSAVKYYFLTA---------TGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVA 769
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Planmine SMEST
Match: SMESG000056847.1 (SMESG000056847.1) HSP 1 Score: 1518.06 bits (3929), Expect = 0.000e+0 Identity = 783/831 (94.22%), Postives = 805/831 (96.87%), Query Frame = 2
Query: 3371 LIDSCETTAHSKITTLPNSGWLWKG-DTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKCVXXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDXXXXXXXXXXYAIPRVSRCECVSKFLSLSEDQMKQYIGSNDLKELKMILEDSCVYIYHNKSKTCY 5860
+I+ AH KITTL +SGWLWKG DTYFINPDCICCTESTE LQ+HPDLRIKSRIKVPNKENK IGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKIN N PNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGM+GMIGKS+ F+CMEKHGLVALLSDVELSENAENPQ+LDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSIS+SYAIPRVS+ S+FL+ S+++MK+ I D ++K I++DS ++IYHNKSKTCY
Sbjct: 242 IIEPILVAAHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFDSMSSQSISNSYAIPRVSKAIKESEFLNSSKEKMKESIELYDSGDIKRIIKDSYIFIYHNKSKTCY 1072 HSP 2 Score: 208.379 bits (529), Expect = 3.979e-54 Identity = 120/305 (39.34%), Postives = 177/305 (58.03%), Query Frame = 2
Query: 743 ICCFEPLDKLSK--DIKVNSQVFC---QQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPL-----ECVENAKLHFIFDKIVDTGKIFYVD-CE-EDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMP 1621
ICC E + L + D+++ S++ + GG C+W+GLING+ +GI D + R+ EG + L E+ K FI DKIVD KI+ + CE E+ +G IN +G+++ FIGE+KW G+IN+EKCVGLDME+E E GM+G+I + RF+CMEKHGL+ +LS+V L + N +L SG+I P+K++R +E + + + IK + V VK N + LKG L+W G MN + VC ++L Q+HENG+NG FWR ++ R K IAT ++ P
Sbjct: 277 ICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEP 581 HSP 3 Score: 78.5666 bits (192), Expect = 5.386e-14 Identity = 76/281 (27.05%), Postives = 118/281 (41.99%), Query Frame = 2
Query: 2621 QLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWK-------------WSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKR------GALFKSEEFIISK--SELKHVKEINLNVVDPFNVREIENGRQINKLTCYKSKGAIKILNIKWRGI-VNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTA 3397
++KW G I+ + C+G + G NG G+ + F C +KHG++ L+ V E E + + G I N E+ K+ + KNIK N I K W G +N + V +E+++ E G++G F + Q+ S KR ++K E ++I E++ KEI +N + T Y+ +KW G+ N G EL + GTDGTFG + +F C GVL P + TA
Sbjct: 417 EVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDV-ELSENAENPQV--LDSGMIAPNKFIRFQEERSKKYLDD---KNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFL---------TATGYQDLFG----TVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTA 678 HSP 4 Score: 76.2554 bits (186), Expect = 2.193e-13 Identity = 75/293 (25.60%), Postives = 125/293 (42.66%), Query Frame = 2
Query: 446 IGKPKGASMNKYIAIQGKTKSFV-KLFWKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLPLADNDELTANNICCFEP------LDKLSKDIKVNSQVFCQQ----LKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSR-ILKIEGRIRFIPLECVENAKLH-FIFDKIVDTGKIFYVDCEEDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKC--VGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNV 1279
IGKP + N G+ + F+ ++ W G+IN+ C+G ++ E G G G+ + F C G++ L++D E +E + + + D+ + N F+ LD K+IK+N V +Q LK GK +W+G +N IE D+ H R I+ G+ R I K ++ I + +IF ++ + N A + G +KW G ++ C GL+++D G DG F C HG++ L+NV
Sbjct: 396 IGKPIKINFN---YPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDV----ELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLD--DKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGK-RVIATSVNHVYKYEPYVIKTIPEEIQIF-------KEIVINSAVKYYFLTATGYQDLFGTVKWTG-VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNV 670 HSP 5 Score: 74.7146 bits (182), Expect = 8.066e-13 Identity = 95/399 (23.81%), Postives = 161/399 (40.35%), Query Frame = 2
Query: 2627 KWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSIC----CTVEKNI---TKFQANCKLKNIKSNRKAIW--KWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHVKE----INLNVVDPFNVREIENGR----------QINKLTCYKSKGAIKIL--NIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIK---VPNKENKQIGGSCEWIGLI-NGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHD 3733
+W GLI+ + LG + GTNG F ++F CE G+L+ + + + KP ++ D +D N I C E I + N N + NR I KW+G +ND + +G++M E +E G +G K Q F + K G + ++S EL E ++ ++ P + R ++N+ K L ++W G +N L EL E G++GTF + + +R + ++K + Y I E +Q ++ I S +K + + + G+ +W G+ N G+ +D+ + GT+G F R+FTC+ G GVL N+ D
Sbjct: 313 EWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFH--DKESEKP-QFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGR-NRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLV-----ALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNH---------------------VYKYEPYVIKT-------IPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASD 673 HSP 6 Score: 65.0846 bits (157), Expect = 6.578e-10 Identity = 89/382 (23.30%), Postives = 164/382 (42.93%), Query Frame = 2
Query: 524 WKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLP--LADNDELTANNICCFEPLDKLSKDIKVN-SQVFCQQLKAGGKCKWMGLINGKGYVGIEFDE--------IHRRAERFNELSRILKIEGRIRFIP-LECVENAKLHFIFDK-IVDTGKIFYVDCEEDRDYLGN----FAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLL--NGQANLKGTLKWHGL-MNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLS 1609
W G IN LG + +GT G F +++FTC G+GVL+L + ES E+ + + D +++ + + C E + K IK+N + + G+ KW G IN + VG++ +E + +++RF + + G + + +E ENA+ + D ++ K E + YL + + + + G+L+WIG +N ++++ + E G +G + + K + T +++V YKY+ P I +T +E + I + V L G +L GT+KW G+ N+ ++L GT+G F RLF C++ + N++
Sbjct: 314 WIGLINGQEALGITMDND-VKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKES-EKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEK----HGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHV--YKYE------PYVI----------KTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVA 671 HSP 7 Score: 62.7734 bits (151), Expect = 3.249e-9 Identity = 48/188 (25.53%), Postives = 86/188 (45.74%), Query Frame = 2
Query: 3227 KWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINK 3787
+W G++NG+ +G + V+ GT+G F +F C +GVL+ E + E+ I + Y I+P C E+ + K IK PN N+ G +W G IN ++ +G+ M+ +++ G NG+ + F C G++ L ++ + +E PQ + ++ NK
Sbjct: 313 EWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIA----DKIVDINKIYSISP---CEGENGIGIGK----PIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNK 488
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Planmine SMEST
Match: SMESG000056847.1 (SMESG000056847.1) HSP 1 Score: 1495.33 bits (3870), Expect = 0.000e+0 Identity = 765/814 (93.98%), Postives = 780/814 (95.82%), Query Frame = 2
Query: 3227 KWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKG-DTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKCVXXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFD 5665
KW G+VN +G E++ +E GTDG F +F+ +RG L +EE I S AH KITTL +SGWLWKG DTYFINPDCICCTESTE LQ+HPDLRIKSRIKVPNKENK IGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKIN N PNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGM+GMIGKS+ F+CMEKHGLVALLSDVELSENAENPQ+LDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFD
Sbjct: 296 KWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIIS----AHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTAKVVSPENVKKSETSDQIVCGLNSSVIAGDNKGIQGNANSCYFDSALFALFVKSDVLDYLISPIINEQEADPITKEFREIIAWRIVYPLRKNGFVSFHHTQEMRNVIQKYGAKFAEMMKQETDMENVSTLLSKLCPKEQLLSIIPHNGCKTNSMFMQLFLTVDKKVPFMTSEEMLKISMVQNDIMFNELPTCLIMQAPRDAKGTNSYKYALPLNEIEISQICSNYLKNCSICNGEAEFQCKTCLGDELDITCTFLCSQHKCQHPACTKLLPDTVKSKSKVFMELQAIICIEKCHFVSFVKQVERLTNEQVEKLRAKQMDIKNEINWFFFD 1105 HSP 2 Score: 249.21 bits (635), Expect = 5.910e-67 Identity = 155/355 (43.66%), Postives = 204/355 (57.46%), Query Frame = 2
Query: 2789 MKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHVKEINLN------------VVDPFNVREIENGRQINKLTCYKSKGAIKILN---------IKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINK 3787
++GHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIIS H+K L ++P + E+ + + + K IK+ N +W G++NG+ +G + V+ GT+G F +F C +GVL+ E + E+ I + Y I+P C E+ + K IK PN N+ G +W G IN ++ +G+ M+ +++ G NG+ + F C G++ L ++ + +E PQ + ++ NK
Sbjct: 248 VEGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIIS----AHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIA----DKIVDINKIYSISP---CEGENGIGIGK----PIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNK 586 HSP 3 Score: 230.72 bits (587), Expect = 5.464e-61 Identity = 138/383 (36.03%), Postives = 211/383 (55.09%), Query Frame = 2
Query: 524 WKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLI-----LINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSK--DIKVNSQVFC---QQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPL-----ECVENAKLHFIFDKIVDTGKIFYVD-CE-EDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMP 1621
W G +N++ +G E+ E +GT+G F + +LF + RG L +I+ +K + D + + ICC E + L + D+++ S++ + GG C+W+GLING+ +GI D + R+ EG + L E+ K FI DKIVD KI+ + CE E+ +G IN +G+++ FIGE+KW G+IN+EKCVGLDME+E E GM+G+I + RF+CMEKHGL+ +LS+V L + N +L SG+I P+K++R +E + + + IK + V VK N + LKG L+W G MN + VC ++L Q+HENG+NG FWR ++ R K IAT ++ P
Sbjct: 297 WSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISAHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEP 679 HSP 4 Score: 94.3597 bits (233), Expect = 7.213e-19 Identity = 131/506 (25.89%), Postives = 212/506 (41.90%), Query Frame = 2
Query: 2627 KWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGA----------IDENSICCTVEKNITKFQANCKLKN-IKSNRK------AIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHV----KEINLNVVDPFNVREIENGRQINK-----LTCYKSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSR----IKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKC--VXXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDV 4045
KW GL++ +G N GT+G F + +LF K G L SE + H I RD I+ + ICCT + + + ++K+ IK K +W GL+N E +G+ M+ + KGT+G F ++F +G L +E K K K +++N + + E ENG I K + I +KW G +N E CVG ++ +E G +G G F+C + G++ L+ E + +++ + +SG I P+ + S + D IK +K N E K + G WIG +N I +D D + G+NG F + R GK V+ + N + E + I ++I +I S + G +D G VKWTG +++ C GL++++ + G DG G R+F C HG++A L++V
Sbjct: 296 KWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFK----SEEFIISAHLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDV-KGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLV----ALLSDVELSENAENPQVLDSG--------MIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELK-LKGKLRWIGWMNKLLVCVIELDQDHENGSNGTF-WRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGY-------------QDLFGTVKWTG-VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNV 768 HSP 5 Score: 77.411 bits (189), Expect = 1.010e-13 Identity = 76/281 (27.05%), Postives = 118/281 (41.99%), Query Frame = 2
Query: 2621 QLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPLAAVSECCEMKGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKLKNIKSNRKAIWK-------------WSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKR------GALFKSEEFIISK--SELKHVKEINLNVVDPFNVREIENGRQINKLTCYKSKGAIKILNIKWRGI-VNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTA 3397
++KW G I+ + C+G + G NG G+ + F C +KHG++ L+ V E E + + G I N E+ K+ + KNIK N I K W G +N + V +E+++ E G++G F + Q+ S KR ++K E ++I E++ KEI +N + T Y+ +KW G+ N G EL + GTDGTFG + +F C GVL P + TA
Sbjct: 515 EVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDV-ELSENAENPQV--LDSGMIAPNKFIRFQEERSKKYLDD---KNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEPYVIKTIPEEIQIFKEIVINSAVKYYFL---------TATGYQDLFG----TVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVASDTRFTA 776 HSP 6 Score: 70.0922 bits (170), Expect = 1.954e-11 Identity = 75/330 (22.73%), Postives = 146/330 (44.24%), Query Frame = 2
Query: 701 HLPL--ADNDELTANNICCFEPLDKLSKDI-KVNSQVFCQQLKAGGKC--KWMGLINGKGYVGIEFDEIHRRAERFN----ELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKI------FYVD-----CEEDRDYLGNFAAINLTTR----DGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQ-ANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPS 1615
H P+ + + N+ICC + K+I K + + +K+ K KW GL+N +G+E +E + N +L R + G + F E + +A H + D+G + ++++ C E + L + + +R + ++K G +WIG IN ++ +G+ M+++ + G +GI + F C G++ + N+ K + I++ +K G+ I I K +N NG+ + G +KW G +N+ + + +E E+G NG +++ FEC +K + L ++ S
Sbjct: 251 HKPIKWTRDGAIDENSICC-----TVEKNITKFQANCKLKNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGAL-FKSEEFIISA--HLKITTLRDSGWLWKGGDTYFINPDCICCTESTELLQQHPDLRIKSRIKVPNKENKHIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCEGENGIG---IGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEKHGLVALLSDVELS 568 HSP 7 Score: 64.6994 bits (156), Expect = 7.906e-10 Identity = 88/381 (23.10%), Postives = 164/381 (43.04%), Query Frame = 2
Query: 524 WKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLP--LADNDELTANNICCFEPLDKLSKDIKVN-SQVFCQQLKAGGKCKWMGLINGKGYVGIEFDE--------IHRRAERFNELSRILKIEGRIRFIP-LECVENAKLHFIFDK-IVDTGKIFYVDCEEDRDYLGN----FAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIIN-PDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGL-MNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLS 1609
W G IN LG + +GT G F +++FTC G+GVL+L + ES E+ + + D +++ + + C E + K IK+N + + G+ KW G IN + VG++ +E + +++RF + + G + + +E ENA+ + D ++ K E + YL + + + + G+L+WIG +N ++++ + E G +G + + K + T +++V YKY+ P I P++ KE + +K + G +L GT+KW G+ N+ ++L GT+G F RLF C++ + N++
Sbjct: 412 WIGLINGQEALGITMDND-VKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKES-EKPQFIADKIVDINKIYSISPCEGENGIGIGKPIKINFNYPNGRNRDFIGEVKWTGRINDEKCVGLDMEEEMEHGMNGMIGKSQRFECMEK----HGLVALLSDVELSENAENPQVLDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHV--YKYE------PYVIKTIPEEIQIFKEIVINSAVKYYFLTA---------TGYQDLFGTVKWTGVDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVA 769
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Planmine SMEST
Match: SMESG000056845.1 (SMESG000056845.1) HSP 1 Score: 1291.17 bits (3340), Expect = 0.000e+0 Identity = 626/663 (94.42%), Postives = 640/663 (96.53%), Query Frame = 2
Query: 374 KSVLPTIYCNKLGMDVIKPGAIDQIGKPKGASMNKYIAIQGKTKSFVKLFWKGKINNINCLGCELPEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSKDIKVNSQVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHGLITVLSNVNLYKYDNNVHLLPSGIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTKNLSPSMPIDFIKDIFVEKNQKEFSRGSVRTDDIYHVGQFVKILPFDLFGQIECFHVVYEEMFVQIQLTKDQIKRLPFHQRIDRAAGNAIYSTVILLKDSIAKCSENLEFFNESSLINKECIEYRIPRPMETFRTGDLIKAGKTGNVKYFIVNNRFIINGISCLSVMESILGEAEEYLPESEAMKVDNSELEMKYFQGVFIDPKSIRSFEKCEINDFCIGNRVEFMSMDRKSSYNGRIKSTGIANKTIPSCVVQM 2362
+SVLPTIYCNKLGMDVIKPGAIDQIGKPKGASMNKYIAIQGKTKSFVKLFWKGKINNINCLGCELPE+W EGTEGTFGR+KLFTCSY RGVLI INDAVKSCESA+ESN LPL DNDELT NNICCFEPL+KLS DI+VNS+VFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNF AINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDE EF MDGIINQDNRFDCMEKHGLITVLSN+N+ + + IINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKW+GLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLT+NLSPSMPIDFIKDIFVEKNQKEFSRGSVRT DIYHVGQFVKILPFDLFGQIECFHVVYEEMFVQ+QLTKDQIKRLPFHQRIDRAA NAIYSTVILLKDSIAKCSENLEFFNESSLINKECIEYRIPRPMETFRTGDLIKAGKTGNVKYFIVNNRFIINGISCLSVMESILGEAEEYLPESEAMKVDNSELEMKYFQGVFIDPKSIRSFEKCEINDFCIGNRVEFMSMDRKSSYNGRIKSTGIANKTIPSCVVQM
Sbjct: 410 QSVLPTIYCNKLGMDVIKPGAIDQIGKPKGASMNKYIAIQGKTKSFVKLFWKGKINNINCLGCELPEYWREGTEGTFGRHKLFTCSYSRGVLIPINDAVKSCESADESNDLPLTDNDELTENNICCFEPLEKLSNDIEVNSRVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFGAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDEMEFTMDGIINQDNRFDCMEKHGLITVLSNINM----TIMFICYLWIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWYGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTQNLSPSMPIDFIKDIFVEKNQKEFSRGSVRTGDIYHVGQFVKILPFDLFGQIECFHVVYEEMFVQVQLTKDQIKRLPFHQRIDRAASNAIYSTVILLKDSIAKCSENLEFFNESSLINKECIEYRIPRPMETFRTGDLIKAGKTGNVKYFIVNNRFIINGISCLSVMESILGEAEEYLPESEAMKVDNSELEMKYFQGVFIDPKSIRSFEKCEINDFCIGNRVEFMSMDRKSSYNGRIKSTGIANKTIPSCVVQM 1068 HSP 2 Score: 257.299 bits (656), Expect = 8.947e-69 Identity = 155/327 (47.40%), Postives = 196/327 (59.94%), Query Frame = 2
Query: 569 PEFWSEGTEGTFGRYKLFTCSYGRGVLILINDAVKSCESAEESNHLPLADNDELTANNICCFEPLDKLSKDIKVNSQVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERF-NELSRILKIEGRIRFIPLECV-ENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFAAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDETEFGMDGIINQDNRFDCMEKHG-LITVLSNVNLYKYDNNVHLLPSGIINPDKYLR----CKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWHGLMNNVPVCAVQLLQEHENG 1528
PEFWSEGTEGTFGRYKLFTCSY +GVLI INDAVKSCESA+ESNHLPLADNDELTANNICCFEPLDKLSKDIKVNS+VFCQQLKAGGKC WMGLINGKGYVGIEFDEI N +S ILKI+G+IR IP++ V + + ++ G I + + + + AI GK+K F+ +L W GKINN C+G ++ + G +G + F C G LI + V + + + LP + + D+ C E +++ D VN ++ Q G KW GL+N ++ + H
Sbjct: 276 PEFWSEGTEGTFGRYKLFTCSYDKGVLIPINDAVKSCESADESNHLPLADNDELTANNICCFEPLDKLSKDIKVNSRVFCQQLKAGGKCNWMGLINGKGYVGIEFDEIIPDGNSTQNSISEILKIQGQIRMIPVQSVLPTIYCNKLGMDVIKPGAIDQIGKPKGAS-MNKYIAIQ-----GKTKSFV-KLFWKGKINNINCLGCELPEYWREGTEGTFGRHKLFTCSYSRGVLIPINDAVKSCESADESNDLP--LTDNDELTENNICCFEPL-------EKLSNDIEVNSRVFCQQLKAGGKCKWMGLINGKGYVGIEFDEIHRRA 586 HSP 3 Score: 238.039 bits (606), Expect = 7.383e-63 Identity = 196/584 (33.56%), Postives = 297/584 (50.86%), Query Frame = 2
Query: 2693 GTNGTFGQDKLFACEDKHGILIPLAAVSECCEM---KGHKPIKWTRDGAIDENSICCTVEKNITKFQANCKL-KNIKSNRKAIWK---------WSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELK--HVKEINLNVVDPFNVREI--ENGRQINKLTCY--KSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKITTLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKSRIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVKGTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINKIYSISPCXXXXXXXXXXXXXXXLNSPNGRNRDFIGEVKWTGRINDEKCVXXXXXXXXXXXXXXXXXKSRIFQCMEKHGLVALLSDVELSENAENPQILDSGMIAPNKFIRFQEERSKKYLDDKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGKRVIATSVNHVYKYEP 4387
GT GTFG+ KLF C G+LIP+ + CE H P+ + + N+ICC F+ KL K+IK N + + W GL+N +G+E +E + DGN + + + +G + I +S L + ++ ++V+ P + +I G +NK K+K +K+ W+G +N C+GCEL GT+GTFG +F C RGVLIP + + SCE+ S L ++ L + + ICC E E L D+ + SR+ + + GG C+W+GLING+ +GI D + R+ EG + L E+ K FI DKIVD KI+ + E+ +G INL + +G+++ FIGE+KW G+IN+EKCVGLDME+EME MDG+I + F CMEKHGL+ +LS++ ++ I +I P+K++R +E + + + IK + V VK N + LKG L+W G MN + VC ++L Q+HENG+NG FWR ++ R K IAT ++ P
Sbjct: 282 GTEGTFGRYKLFTCSYDKGVLIPINDAVKSCESADESNHLPL--ADNDELTANNICC--------FEPLDKLSKDIKVNSRVFCQQLKAGGKCNWMGLINGKGYVGIEFDEII---PDGNSTQNSISEILKIQGQI----RMIPVQSVLPTIYCNKLGMDVIKPGAIDQIGKPKGASMNKYIAIQGKTKSFVKLF---WKGKINNINCLGCELPEYWREGTEGTFGRHKLFTCSYSRGVLIPINDAVKSCESADESNDLPLTDNDELTENN--------ICCFEPLEKLSN--DIEVNSRVFC---QQLKAGGKCKWMGLINGKGYVGIEFDEIHRRAERFNELSRILKIEGRIRFIPL-----ECVENAKLHFIFDKIVDTGKIFYVD--CEEDRDYLGNFGAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDEMEFTMDGIINQDNRFDCMEKHGLITVLSNINMTIMF----ICYLWIINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQANLKGTLKWYGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTQNLSPSMP 821 HSP 4 Score: 102.449 bits (254), Expect = 2.962e-21 Identity = 117/441 (26.53%), Postives = 185/441 (41.95%), Query Frame = 2
Query: 2516 GIPVIDPEFI-RIIEGVAVEPGKFIVFTCNNQRHSVQLKWKGLIDQKYCLGCVANFQCNFGTNGTFGQDKLFACEDKHGILIPL-AAVSECCEMKGHKPIKWTRDGAIDENSICC--TVEKNITKFQANCKL--KNIKSNRKAIWKWSGLVNDVEVIGVEMNESLEKGTDGNFCKIQLFRSVHKRGALFKSEEFIISKSELKHVKEINLNVVDPFNVREIENGRQIN-----KLTCYKSKGAIKILNIKWRGIVNGELCVGCELSGPVEWGTDGTFGNKIVFKCPARRGVLIPTEELIDSCETTAHSKIT-TLPNSGWLWKGDTYFINPDCICCTESTESLQKHPDLRIKS----RIKVPNKENKQIGGSCEWIGLINGQEALGITMDNDVK-GTNGIFSYFRMFTCEGGKGVLMLAENIFHDKESEKPQFIADKIVDINK 3787
G+ VI P I +I + K+I + V+L WKG I+ CLGC GT GTFG+ KLF C G+LIP+ AV C + T + + EN+ICC +EK + N ++ + +K+ K KW GL+N +G+E +E + N +L R + G + + ++L + + ++ F V E+ + LT K I +KW G +N E CVG ++ +E+ DG F C + G++ T S I T+ +LW INPD + T + RIK +K+ N + + G+ +W GL+N + + + + GTNG F R+F C + L +N+ S FI D V+ N+
Sbjct: 422 GMDVIKPGAIDQIGKPKGASMNKYIAIQ-GKTKSFVKLFWKGKINNINCLGCELPEYWREGTEGTFGRHKLFTCSYSRGVLIPINDAVKSCESADESNDLPLTDNDELTENNICCFEPLEKLSNDIEVNSRVFCQQLKAGGKC--KWMGLINGKGYVGIEFDEIHRRAERFN----ELSRILKIEGRIRFIPLECVENAKLHFIFDKIVDTGKIFYVDCEEDRDYLGNFGAINLTTRDGKSKQFIGELKWIGKINNEKCVGLDMEDEMEFTMDGIINQDNRFDCMEKHGLI------------TVLSNINMTIMFICYLW-----IINPDKYLRCKETFGDECIKAQRIKKDGMVNVKLLNGQ-ANLKGTLKWYGLMNNVPVCAVQLLQEHENGTNGRFWRTRLFECRDKLAIATLTQNL---SPSMPIDFIKDIFVEKNQ 834 HSP 5 Score: 52.373 bits (124), Expect = 5.427e-6 Identity = 64/236 (27.12%), Postives = 106/236 (44.92%), Query Frame = 2
Query: 3986 KSRIFQCMEKHGLVALLSDV----ELSENAENPQILDSGMIAPNKFIRFQEERSKKYLD--DKNIKMNEFVIVKQGNPELKLKGKLRWIGWMNKLLVCVIELDQDHENGSNGTFWRRQIVNSRGK-RVIATS--VNHVY--KYEPYVIKTIPEEIQIFKEIVINSAVKYYFLTATGYQDLFGTVKWTG-VDENDCYFFGLELDDRINIGTDGTFGGQRLFTCQNGHGVLAPLNNVA 4657
+ ++F C G++ ++D E ++ + + + D+ + N F+ LD K+IK+N V +Q LK GK W+G +N IE D+ +G++ +I+ +G+ R+I + +Y K VIK P I + S KY + G F + W G ++ +C G EL + GT+GTFG +LFTC GVL P+N+
Sbjct: 289 RYKLFTCSYDKGVLIPINDAVKSCESADESNHLPLADNDELTANNICCFEP------LDKLSKDIKVNSRVFCQQ----LKAGGKCNWMGLINGKGYVGIEFDEIIPDGNSTQNSISEILKIQGQIRMIPVQSVLPTIYCNKLGMDVIK--PGAIDQIGKPKGASMNKY--IAIQGKTKSFVKLFWKGKINNINC--LGCELPEYWREGTEGTFGRHKLFTCSYSRGVLIPINDAV 508 The following BLAST results are available for this feature:
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 3
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Cylindromatosis (turban tumor syndrome), b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035733 ID=SMED30035733|Name=Cylindromatosis (turban tumor syndrome), b|organism=Schmidtea mediterranea sexual|type=transcript|length=5967bpback to top protein sequence of SMED30035733-orf-1 >SMED30035733-orf-1 ID=SMED30035733-orf-1|Name=SMED30035733-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1867bp MHSDKSEDNSIKAVSNIDRQNSATSRTSNDSRDYMANKSVLPTIYCNKLGback to top Annotated Terms
The following terms have been associated with this transcript:
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