Betaine--homocysteine S-methyltransferase 1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035725 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 8
Homology
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Human
Match: BHMT (betaine--homocysteine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:1047]) HSP 1 Score: 395.971 bits (1016), Expect = 1.221e-136 Identity = 186/307 (60.59%), Postives = 228/307 (74.27%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 I G +N AAC +A++VA EG D LV GGVSQTPSYL+ +T + +F +Q VF ++ VDFL+ EYFEHVEEA WAVET P+A T+CIGPEGD++ VP GECAVRLVKAGA+IIG+NCH DP I LK +K+M + A LKAH M QPL Y TPD + QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPWVRARA++EYWE LR +GRP+ + + PD WGVT G EL Q E T + ++++L++ Sbjct: 94 ISGQEVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFE 399
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Human
Match: BHMT2 (betaine--homocysteine S-methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:1048]) HSP 1 Score: 348.206 bits (892), Expect = 1.710e-118 Identity = 161/275 (58.55%), Postives = 202/275 (73.45%), Query Frame = 3 Query: 75 NINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPD 899 ++N AAC LA++VA +G D LV GG+ QT Y + + +FR+Q VF + VDFL+ EYFEHVEEA WAVE KE + P+A T+CIGPEGDM+++ GECAVRLVKAGA+I+G+NC P LK M++M + AGLKAH M+QPLG+ PD +GF+DLPE+PF LE R+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPW+RARA+REYWE L P +GRPF + + PD Sbjct: 89 DVNAAACDLAREVAGKG-DALVAGGICQTSIYKYQKDEARIKKLFRQQLEVFAWKNVDFLIAEYFEHVEEAVWAVEVLKESDRPVAVTMCIGPEGDMHDITPGECAVRLVKAGASIVGVNCRFGPDTSLKTMELMKEGLEWAGLKAHLMVQPLGFHAPDCGKEGFVDLPEYPFGLESRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARREYWENLLPASGRPFCPSLSKPD 362
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Human
Match: BHMT2 (betaine--homocysteine S-methyltransferase 2 [Source:HGNC Symbol;Acc:HGNC:1048]) HSP 1 Score: 299.286 bits (765), Expect = 3.288e-100 Identity = 138/229 (60.26%), Postives = 170/229 (74.24%), Query Frame = 3 Query: 213 KQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPD 899 + FT E D + +YFEHVEEA WAVE KE + P+A T+CIGPEGDM+++ GECAVRLVKAGA+I+G+NC P LK M++M + AGLKAH M+QPLG+ PD +GF+DLPE+PF LE R+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPW+RARA+REYWE L P +GRPF + + PD Sbjct: 72 QTFTFSASE--DNMESKYFEHVEEAVWAVEVLKESDRPVAVTMCIGPEGDMHDITPGECAVRLVKAGASIVGVNCRFGPDTSLKTMELMKEGLEWAGLKAHLMVQPLGFHAPDCGKEGFVDLPEYPFGLESRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARREYWENLLPASGRPFCPSLSKPD 298
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Human
Match: BHMT (betaine--homocysteine S-methyltransferase [Source:HGNC Symbol;Acc:HGNC:1047]) HSP 1 Score: 263.848 bits (673), Expect = 5.142e-87 Identity = 122/202 (60.40%), Postives = 149/202 (73.76%), Query Frame = 3 Query: 378 TGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 T E AV +AGA+IIG+NCH DP I LK +K+M + A LKAH M QPL Y TPD + QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPWVRARA++EYWE LR +GRP+ + + PD WGVT G EL Q E T + ++++L++ Sbjct: 45 TPEAAVEHPEAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFE 246
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Zebrafish
Match: bhmt (betaine-homocysteine methyltransferase [Source:NCBI gene;Acc:322228]) HSP 1 Score: 409.068 bits (1050), Expect = 3.682e-142 Identity = 193/306 (63.07%), Postives = 229/306 (74.84%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQH 986 G IN AAC LA++VA+EG D LV GGVSQTPSYL+ + + F+KQ VF ++ VD L+ EYFEHVEEAEWAV+ K P+A TLCIGP+GDM+ V GECAVRLVKAGA+I+G+NCH DP +K + +M +AV AGLKAH+M QPL Y TPD S QGFIDLPEFPFALEPRI TR++M +YAREAY AGIRYIGGCCGFE YHIRAVAEEL+ E G PE S KH LWG GL+MHTKPWVRARA+R+YWEKL+P +GRP + + PD WGVT GH L Q E T ++ L+Q Sbjct: 91 GQQINEAACDLAREVANEG-DALVAGGVSQTPSYLSCKSEEEVKKTFKKQLDVFIKKNVDLLIAEYFEHVEEAEWAVQVLKATGKPVAATLCIGPDGDMHGVTPGECAVRLVKAGADIVGVNCHFDPLTCVKTVVMMKAAVEKAGLKAHYMTQPLAYHTPDCSCQGFIDLPEFPFALEPRILTRWEMQQYAREAYKAGIRYIGGCCGFEPYHIRAVAEELSAERGFLPEASQKHGLWGSGLEMHTKPWVRARARRDYWEKLKPASGRPLCPSMSTPDGWGVTRGHAALMQQKEATTAEQLRPLFQQ 395
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Zebrafish
Match: bhmt (betaine-homocysteine methyltransferase [Source:NCBI gene;Acc:322228]) HSP 1 Score: 408.297 bits (1048), Expect = 5.227e-142 Identity = 193/306 (63.07%), Postives = 229/306 (74.84%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQH 986 G IN AAC LA++VA+EG D LV GGVSQTPSYL+ + + F+KQ VF ++ VD L+ EYFEHVEEAEWAV+ K P+A TLCIGP+GDM+ V GECAVRLVKAGA+I+G+NCH DP +K + +M +AV AGLKAH+M QPL Y TPD S QGFIDLPEFPFALEPRI TR++M +YAREAY AGIRYIGGCCGFE YHIRAVAEEL+ E G PE S KH LWG GL+MHTKPWVRARA+R+YWEKL+P +GRP + + PD WGVT GH L Q E T ++ L+Q Sbjct: 83 GQQINEAACDLAREVANEG-DALVAGGVSQTPSYLSCKSEEEVKKTFKKQLDVFIKKNVDLLIAEYFEHVEEAEWAVQVLKATGKPVAATLCIGPDGDMHGVTPGECAVRLVKAGADIVGVNCHFDPLTCVKTVVMMKAAVEKAGLKAHYMTQPLAYHTPDCSCQGFIDLPEFPFALEPRILTRWEMQQYAREAYKAGIRYIGGCCGFEPYHIRAVAEELSAERGFLPEASQKHGLWGSGLEMHTKPWVRARARRDYWEKLKPASGRPLCPSMSTPDGWGVTRGHAALMQQKEATTAEQLRPLFQQ 387
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Xenopus
Match: kat6a (K(lysine) acetyltransferase 6A [Source:Xenbase;Acc:XB-GENE-6076141]) HSP 1 Score: 394.045 bits (1011), Expect = 4.489e-136 Identity = 186/308 (60.39%), Postives = 226/308 (73.38%), Query Frame = 3 Query: 57 KII*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 K I G +N AAC +A++VA+EG D LV GGVSQTPSYL+ + + IFRKQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGP+GD+N V GECAVRL KAGA+++G+NCH DP + +K+M + A +KAH M QPL Y TPD QGFIDLPEFPFALEPRI TR+D+HKYAREAY+ G+RYIGGCCGFE YH RA+AEELA E G P GS+KH WG GL+MHTKPWVRARA+R+YWEKL P +GRP + + PD WGVT G +L Q E T + ++ L+ Sbjct: 84 KKISGQKVNEAACDIAREVANEG-DALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPQGDLNGVTPGECAVRLAKAGASVVGVNCHFDPMTCIATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYAREAYNLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPPGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPCCPSMSKPDAWGVTKGDADLMQQKEATTEQQLIDLF 390
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Xenopus
Match: kat6a (K(lysine) acetyltransferase 6A [Source:Xenbase;Acc:XB-GENE-6076141]) HSP 1 Score: 394.045 bits (1011), Expect = 5.310e-136 Identity = 186/308 (60.39%), Postives = 226/308 (73.38%), Query Frame = 3 Query: 57 KII*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 K I G +N AAC +A++VA+EG D LV GGVSQTPSYL+ + + IFRKQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGP+GD+N V GECAVRL KAGA+++G+NCH DP + +K+M + A +KAH M QPL Y TPD QGFIDLPEFPFALEPRI TR+D+HKYAREAY+ G+RYIGGCCGFE YH RA+AEELA E G P GS+KH WG GL+MHTKPWVRARA+R+YWEKL P +GRP + + PD WGVT G +L Q E T + ++ L+ Sbjct: 89 KKISGQKVNEAACDIAREVANEG-DALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPQGDLNGVTPGECAVRLAKAGASVVGVNCHFDPMTCIATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYAREAYNLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPPGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPCCPSMSKPDAWGVTKGDADLMQQKEATTEQQLIDLF 395
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Xenopus
Match: kat6a (K(lysine) acetyltransferase 6A [Source:Xenbase;Acc:XB-GENE-6076141]) HSP 1 Score: 393.275 bits (1009), Expect = 8.777e-136 Identity = 186/308 (60.39%), Postives = 226/308 (73.38%), Query Frame = 3 Query: 57 KII*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 K I G +N AAC +A++VA+EG D LV GGVSQTPSYL+ + + IFRKQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGP+GD+N V GECAVRL KAGA+++G+NCH DP + +K+M + A +KAH M QPL Y TPD QGFIDLPEFPFALEPRI TR+D+HKYAREAY+ G+RYIGGCCGFE YH RA+AEELA E G P GS+KH WG GL+MHTKPWVRARA+R+YWEKL P +GRP + + PD WGVT G +L Q E T + ++ L+ Sbjct: 90 KKISGQKVNEAACDIAREVANEG-DALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPQGDLNGVTPGECAVRLAKAGASVVGVNCHFDPMTCIATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYAREAYNLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPPGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPCCPSMSKPDAWGVTKGDADLMQQKEATTEQQLIDLF 396
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Xenopus
Match: kat6a (K(lysine) acetyltransferase 6A [Source:Xenbase;Acc:XB-GENE-6076141]) HSP 1 Score: 392.889 bits (1008), Expect = 1.517e-135 Identity = 186/308 (60.39%), Postives = 226/308 (73.38%), Query Frame = 3 Query: 57 KII*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 K I G +N AAC +A++VA+EG D LV GGVSQTPSYL+ + + IFRKQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGP+GD+N V GECAVRL KAGA+++G+NCH DP + +K+M + A +KAH M QPL Y TPD QGFIDLPEFPFALEPRI TR+D+HKYAREAY+ G+RYIGGCCGFE YH RA+AEELA E G P GS+KH WG GL+MHTKPWVRARA+R+YWEKL P +GRP + + PD WGVT G +L Q E T + ++ L+ Sbjct: 92 KKISGQKVNEAACDIAREVANEG-DALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPQGDLNGVTPGECAVRLAKAGASVVGVNCHFDPMTCIATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYAREAYNLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPPGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPCCPSMSKPDAWGVTKGDADLMQQKEATTEQQLIDLF 398
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Xenopus
Match: kat6a (K(lysine) acetyltransferase 6A [Source:Xenbase;Acc:XB-GENE-6076141]) HSP 1 Score: 392.504 bits (1007), Expect = 7.240e-135 Identity = 186/308 (60.39%), Postives = 226/308 (73.38%), Query Frame = 3 Query: 57 KII*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 K I G +N AAC +A++VA+EG D LV GGVSQTPSYL+ + + IFRKQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGP+GD+N V GECAVRL KAGA+++G+NCH DP + +K+M + A +KAH M QPL Y TPD QGFIDLPEFPFALEPRI TR+D+HKYAREAY+ G+RYIGGCCGFE YH RA+AEELA E G P GS+KH WG GL+MHTKPWVRARA+R+YWEKL P +GRP + + PD WGVT G +L Q E T + ++ L+ Sbjct: 124 KKISGQKVNEAACDIAREVANEG-DALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPQGDLNGVTPGECAVRLAKAGASVVGVNCHFDPMTCIATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYAREAYNLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPPGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPCCPSMSKPDAWGVTKGDADLMQQKEATTEQQLIDLF 430
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Mouse
Match: Gm5096 (predicted gene 5096 [Source:MGI Symbol;Acc:MGI:3643681]) HSP 1 Score: 392.889 bits (1008), Expect = 1.399e-135 Identity = 181/307 (58.96%), Postives = 226/307 (73.62%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 I G +N AAC +A++VA EG D LV GGVSQTPSYL+ + + IFR+Q VF ++ VDFL+ EYFEHVEEA WAVE K P+A T+CIGPEGD++ VP GECAVRLVKAGA+I+G+NCH DP + L+ +K+M + A LKA+ M QPL Y TPD QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPW+RARA++EYW+ LR +GRP+ + + PD WGVT G EL Q E T + ++ +L++ Sbjct: 94 ISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFE 399
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Mouse
Match: Bhmt (betaine-homocysteine methyltransferase [Source:MGI Symbol;Acc:MGI:1339972]) HSP 1 Score: 392.889 bits (1008), Expect = 1.399e-135 Identity = 181/307 (58.96%), Postives = 226/307 (73.62%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 I G +N AAC +A++VA EG D LV GGVSQTPSYL+ + + IFR+Q VF ++ VDFL+ EYFEHVEEA WAVE K P+A T+CIGPEGD++ VP GECAVRLVKAGA+I+G+NCH DP + L+ +K+M + A LKA+ M QPL Y TPD QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPW+RARA++EYW+ LR +GRP+ + + PD WGVT G EL Q E T + ++ +L++ Sbjct: 94 ISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSEVEVKKIFRQQLEVFMKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIVGVNCHFDPSVSLQTVKLMKEGLEAARLKAYLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWIRARARKEYWQNLRIASGRPYNPSMSRPDAWGVTKGAAELMQQKEATTEQQLRELFE 399
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Mouse
Match: Bhmt2 (betaine-homocysteine methyltransferase 2 [Source:MGI Symbol;Acc:MGI:1891379]) HSP 1 Score: 331.643 bits (849), Expect = 3.149e-112 Identity = 159/274 (58.03%), Postives = 198/274 (72.26%), Query Frame = 3 Query: 78 INRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPD 899 +N AAC LA++VA G ++ G + QT Y +T +NIFR Q VF + VDFL+ EYFEHVEEA WAVE +E P+A T+CIGPEGDM++V GECAV+L +AGA+IIG+NC P+ L+ MK+M + DA L+AH M+Q LG+ TPD GF+DLPE+PF LEPR+ TR+D+ KYAREAY+ GIRYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPW+RARA+REYWE L P +GRPF + + PD Sbjct: 90 VNAAACDLAQEVAGGGGALVAGG-ICQTSLYKYHKDETRIKNIFRLQLEVFARKNVDFLIAEYFEHVEEAVWAVEVLREVGAPVAVTMCIGPEGDMHDVTPGECAVKLARAGADIIGVNCRFGPWTSLQTMKLMKEGLRDASLQAHLMVQCLGFHTPDCGKGGFVDLPEYPFGLEPRVATRWDIQKYAREAYNLGIRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLNMHTKPWIRARARREYWENLLPASGRPFCPSLSKPD 362
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q32LQ4|BHMT1_DANRE (Betaine--homocysteine S-methyltransferase 1 OS=Danio rerio OX=7955 GN=bhmt PE=2 SV=1) HSP 1 Score: 408.683 bits (1049), Expect = 4.208e-141 Identity = 193/306 (63.07%), Postives = 229/306 (74.84%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQH 986 G IN AAC LA++VA+EG D LV GGVSQTPSYL+ + + F+KQ VF ++ VD L+ EYFEHVEEAEWAV+ K P+A TLCIGP+GDM+ V GECAVRLVKAGA+I+G+NCH DP +K + +M +AV AGLKAH+M QPL Y TPD S QGFIDLPEFPFALEPRI TR++M +YAREAY AGIRYIGGCCGFE YHIRAVAEEL+ E G PE S KH LWG GL+MHTKPWVRARA+R+YWEKL+P +GRP + + PD WGVT GH L Q E T ++ L+Q Sbjct: 91 GQQINEAACDLAREVANEG-DALVAGGVSQTPSYLSCKSEEEVKKTFKKQLDVFIKKNVDLLIAEYFEHVEEAEWAVQVLKATGKPVAATLCIGPDGDMHGVIPGECAVRLVKAGADIVGVNCHFDPLTCVKTVAMMKAAVEKAGLKAHYMTQPLAYHTPDCSCQGFIDLPEFPFALEPRILTRWEMQQYAREAYKAGIRYIGGCCGFEPYHIRAVAEELSAERGFLPEASQKHGLWGSGLEMHTKPWVRARARRDYWEKLKPASGRPLCPSMSTPDGWGVTRGHAALMQQKEATTAEQLRPLFQQ 395
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q5XGM3|BHMT1_XENLA (Betaine--homocysteine S-methyltransferase 1 OS=Xenopus laevis OX=8355 GN=bhmt PE=2 SV=1) HSP 1 Score: 395.971 bits (1016), Expect = 3.949e-136 Identity = 185/305 (60.66%), Postives = 225/305 (73.77%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKL 977 I G +N AC +A++VA+EG D LV GGVSQTPSYL+ + + IFRKQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGPEGD+N V GECAVRL KAGA+++G+NCH DP + +K+M + A +KAH M QPL Y TPD QGFIDLPEFPFALEPRI TR+D+HKYAR AYD G+RYIGGCCGFE YH RA+AEELA E G P+GS+KH WG GL+MHTKPWVRARA+R+YWEKL P +GRP+ + + PD WGVT G +L Q E T + +++ L Sbjct: 91 ISGQKVNEVACDIAREVANEG-DALVAGGVSQTPSYLSCKSEVEVKGIFRKQLDVFIKKNVDFLIAEYFEHVEEAVWAVEVLKESGKPVAATLCIGPEGDLNGVSPGECAVRLAKAGASVVGVNCHFDPMTCVATVKLMKEGLVAAKVKAHLMTQPLAYHTPDCGKQGFIDLPEFPFALEPRIVTRWDIHKYARAAYDLGVRYIGGCCGFEPYHTRAIAEELAPERGFLPKGSEKHGSWGSGLEMHTKPWVRARARRDYWEKLPPASGRPYCPSMSKPDEWGVTKGDADLMQQKEATTEQQLKDL 394
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q93088|BHMT1_HUMAN (Betaine--homocysteine S-methyltransferase 1 OS=Homo sapiens OX=9606 GN=BHMT PE=1 SV=2) HSP 1 Score: 395.971 bits (1016), Expect = 5.863e-136 Identity = 186/307 (60.59%), Postives = 228/307 (74.27%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 I G +N AAC +A++VA EG D LV GGVSQTPSYL+ +T + +F +Q VF ++ VDFL+ EYFEHVEEA WAVET P+A T+CIGPEGD++ VP GECAVRLVKAGA+IIG+NCH DP I LK +K+M + A LKAH M QPL Y TPD + QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPWVRARA++EYWE LR +GRP+ + + PD WGVT G EL Q E T + ++++L++ Sbjct: 94 ISGQEVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFE 399
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q5RFG2|BHMT1_PONAB (Betaine--homocysteine S-methyltransferase 1 OS=Pongo abelii OX=9601 GN=BHMT PE=2 SV=1) HSP 1 Score: 394.815 bits (1013), Expect = 1.314e-135 Identity = 186/307 (60.59%), Postives = 227/307 (73.94%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 I G +N AAC +A++VA EG D LV GGVSQTPSYL+ +T + +F +Q VF ++ VDFL+ EYFEHVEEA WAVET P+A T+CIGPEGD++ VP GECAVRLVKAGA+IIG+NCH DP I LK +K+M + A LKAH M QPL Y TPD + QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ GIRYIGGCCGFE YHIRA+AEELA E G P S+KH WG L MHTKPWVRARA++EYWE LR +GRP+ + + PD WGVT G EL Q E T + ++++L++ Sbjct: 94 ISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPVAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNMGIRYIGGCCGFEPYHIRAIAEELAPERGFLPPASEKHGSWGSALDMHTKPWVRARARKEYWENLRIASGRPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFE 399
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. UniProt/SwissProt
Match: sp|Q5I597|BHMT1_BOVIN (Betaine--homocysteine S-methyltransferase 1 OS=Bos taurus OX=9913 GN=BHMT PE=2 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 2.396e-135 Identity = 182/307 (59.28%), Postives = 228/307 (74.27%), Query Frame = 3 Query: 63 I*GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 I G +N AAC +A++VA EG D LV GGVSQTPSYL+ +T + +F++Q VF ++ VDFL+ EYFEHVEEA WAVE K P+A T+CIGPEGD+++V GECAVRLVKAGA+I+G+NCH DP I L+ +K+M + AGLKAH M QPL Y TPD QGFIDLPEFPF LEPR+ TR+D+ KYAREAY+ G+RYIGGCCGFE YHIRA+AEELA E G P S+KH WG GL MHTKPW+RARA++EYWE L+ +GRP+ + + PD WGVT G EL Q E T + ++ +L++ Sbjct: 94 ISGQKVNEAACDIARQVADEG-DALVAGGVSQTPSYLSCKSETEVKKVFQQQLEVFVKKNVDFLIAEYFEHVEEAVWAVEALKASGKPVAATMCIGPEGDLHSVTPGECAVRLVKAGASIVGVNCHFDPTISLQTVKLMKEGLEAAGLKAHLMSQPLAYHTPDCGKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCCGFEPYHIRAIAEELAPERGFLPLASEKHGSWGSGLDMHTKPWIRARARKEYWENLQIASGRPYNPSMSKPDAWGVTKGTAELMQQKEATTEQQLRELFE 399
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. TrEMBL
Match: A0A1E1XH73 (Putative cysteine s-methyltransferase (Fragment) OS=Amblyomma aureolatum OX=187763 PE=2 SV=1) HSP 1 Score: 440.269 bits (1131), Expect = 3.480e-151 Identity = 204/306 (66.67%), Postives = 244/306 (79.74%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEH-GRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 GA+IN AACKLA++VASE K LV GG+SQTPSYL+G K Q+IFRKQ +VF + ++DFL+CEYFEHVEE E A+E KE LPI TLCIGPEGDM+ V GECAVR+VKAGAN++GINCH DPF+VL+ +K+MI AV AGLKAHF+ QPL Y TPD QGFIDLPEFPFALEPR+C+R+D+ +YAREAY+ G+RYIGGCCGFE YH+RA+AEEL+ E G P+ S KHD WG GL+MHTKPWVRARA R YWE L+P TGRPF++A++ PD WGVTAG+ ELKQ T EIEKL + Sbjct: 86 GADINEAACKLAQEVASE-KKALVAGGISQTPSYLSGCSKAEVQDIFRKQVSVFVKNKLDFLICEYFEHVEEMEMAIEVCKETGLPIVATLCIGPEGDMHGVSAGECAVRMVKAGANVVGINCHFDPFVVLEGVKLMIEAVRAAGLKAHFIPQPLAYHTPDAGKQGFIDLPEFPFALEPRVCSRWDIQRYAREAYELGVRYIGGCCGFEPYHVRAIAEELSAERGGALPDASQKHDTWGEGLRMHTKPWVRARASRAYWENLKPSTGRPFSSAFSQPDNWGVTAGNAELKQQTSATTREEIEKLQK 390
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. TrEMBL
Match: A0A2R5L490 (Putative cysteine s-methyltransferase OS=Ornithodoros turicata OX=34597 PE=4 SV=1) HSP 1 Score: 437.958 bits (1125), Expect = 3.359e-150 Identity = 205/306 (66.99%), Postives = 247/306 (80.72%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKE-HGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 G +IN AACK+AK+VASEG LV GGVSQTP++L+G K Q FRKQ VF E ++DFL+CEYFEHVEE E A++ KE LPI T+CIGPEGD++ V GECAVR+VKAGA+++G+NCH DPF+VL+ +K+MI AV+ +GLKAHF+ QPL Y TPD QGFIDLPEFPFALEPR+CTR+DM +YAREAY+ G+RYIGGCCGFE YHIRA+AEELA++ H PE S+KHD WG GLKMHTKPWVRARA REYWE L+P TGRPF++AY+ PD WGVTAG +ELKQ AE T E+EKL+Q Sbjct: 89 GEDINVAACKIAKEVASEGT-ALVAGGVSQTPAFLSGRSKAQVQEEFRKQVRVFIENQLDFLVCEYFEHVEEIEIAIKVCKETPLPIVATMCIGPEGDLHGVSAGECAVRMVKAGAHVVGVNCHFDPFVVLETVKLMIDAVNASGLKAHFITQPLAYHTPDAGKQGFIDLPEFPFALEPRVCTRWDMQRYAREAYEMGVRYIGGCCGFEPYHIRALAEELAEDRHSALPEASEKHDPWGAGLKMHTKPWVRARAFREYWETLKPATGRPFSSAYSQPDNWGVTAGAEELKQKAEDTTKEELEKLHQ 393
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. TrEMBL
Match: T1JFQ0 (Hcy-binding domain-containing protein OS=Strigamia maritima OX=126957 PE=4 SV=1) HSP 1 Score: 434.876 bits (1117), Expect = 6.329e-149 Identity = 195/307 (63.52%), Postives = 241/307 (78.50%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQHM 989 G+ IN AAC++ K+VA+EG D L LGG+SQTPSYL+G+GK Q F+KQ VF + ++DF+LCEYFEHVEE EWA+E K+F P+A T+CIGP GD++ V G+CAVR+ +AGA+I+G+NCH DPF+ L +K+M +A+ D GL H M QPLG TPD QGFIDLPEFPFALEPRICTR+DM KYAREA++AG+RYIGGCCGFE YHIRAVAEELA E GR P SDKHD+W GLKMHTKPWVRARA R YWE+L+P +GRP++A A PD WGVTAGH+ LKQHA++T + E K + + Sbjct: 90 GSAINEAACQIVKRVAAEG-DALTLGGLSQTPSYLSGLGKEAVQAEFKKQVQVFVKHDLDFVLCEYFEHVEEIEWAIEACKQFGKPVAATMCIGPHGDLHGVSAGQCAVRMARAGADIVGLNCHFDPFVTLDTIKVMKAALQDEGLDRHLMTQPLGLHTPDAGRQGFIDLPEFPFALEPRICTRWDMQKYAREAFEAGVRYIGGCCGFEPYHIRAVAEELAPERGRLPAASDKHDMWAQGLKMHTKPWVRARASRTYWEQLKPASGRPYSACMARPDGWGVTAGHETLKQHAKVTSEDEQNKALEFL 395
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. TrEMBL
Match: A0A4Y2L3D9 (Betaine--homocysteine S-methyltransferase 1 (Fragment) OS=Araneus ventricosus OX=182803 GN=BHMT PE=4 SV=1) HSP 1 Score: 430.639 bits (1106), Expect = 1.140e-147 Identity = 195/309 (63.11%), Postives = 244/309 (78.96%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQHMMK 995 G++IN AAC++A++VASEG D LV GG+SQTPSYL+G K + Q FRKQ VF +VDFL+CEYFEH+EE EWA+E +E +LPIA T+CIG EGD++ V GECAVR+ KAGA+++G+NCH DPF +L A+ M A+ AGLK + M QPL ++ PDN QGFIDLPEFPFALEPR+CTR+DM +YAR AY+ G+RYIGGCCGFE+YHIRAV+EELAKE G+ P S KHD WG GL+MHTKPWVRARA+R YWE L+P TGRP +AA++ PD WGVTAG +ELKQ AE T + E++K++ H K Sbjct: 67 GSDINEAACRIAREVASEG-DALVAGGISQTPSYLSGKSKRSVQEEFRKQVQVFVSNKVDFLICEYFEHIEEMEWAIEVCRETSLPIASTMCIGTEGDLHGVGAGECAVRMAKAGAHVVGLNCHFDPFGMLDAIAAMKKALDAAGLKPYLMTQPLAFLCPDNGKQGFIDLPEFPFALEPRVCTRWDMQRYARRAYELGVRYIGGCCGFESYHIRAVSEELAKERGKQPLSSQKHDPWGEGLRMHTKPWVRARARRSYWEGLQPATGRPHSAAFSRPDNWGVTAGSEELKQQAESTTNEELQKMFAHNAK 374
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. TrEMBL
Match: A0A1Z5LG74 (Hcy-binding domain-containing protein (Fragment) OS=Ornithodoros moubata OX=6938 PE=4 SV=1) HSP 1 Score: 431.409 bits (1108), Expect = 1.335e-147 Identity = 203/306 (66.34%), Postives = 244/306 (79.74%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEH-GRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 G +IN AACK+AK+VA+EG D LV GG+SQTPS+L+G K + FRKQ VF + ++DFL+CEYFEHVEE E A++ +E +LP+ ++CIGPEGD++ V GECAVR+VKAGA+++G+NCH DPFIVLK +K+MI AV GLKAHF+ QPL Y TPD QGFIDLPEFPFALEPR+C+R+DM KYAREAY+ GIRYIGGCCGFE YHIRAVAEEL +E G+ P S+KHD WG GLKMHTKPWVRARA REYWE L+P TGRPF AAY+ PD WGVTAG DELKQ AE T E++KL + Sbjct: 88 GEDINAAACKIAKEVAAEG-DALVGGGLSQTPSFLSGKTKEEVKEEFRKQVRVFVDNKLDFLICEYFEHVEEIELAIQVCRETSLPVVSSMCIGPEGDLHGVSAGECAVRMVKAGAHVVGVNCHFDPFIVLKTLKLMIDAVKAEGLKAHFITQPLAYHTPDAGKQGFIDLPEFPFALEPRVCSRWDMQKYAREAYELGIRYIGGCCGFEPYHIRAVAEELVQERGGKLPLASEKHDPWGEGLKMHTKPWVRARAFREYWENLKPATGRPFCAAYSRPDNWGVTAGADELKQKAEDTTKEELQKLQE 392
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Cavefish
Match: bhmt (betaine--homocysteine S-methyltransferase 1 [Source:NCBI gene;Acc:103034807]) HSP 1 Score: 407.527 bits (1046), Expect = 1.484e-141 Identity = 186/305 (60.98%), Postives = 236/305 (77.38%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 G +N AAC LA++VA+EG D LV GGVSQTPSYL+ +T+ + IF+KQ VF +++VDFL+ EYFEHVEEAEWAV+ K P+A ++CIGP+GDM+ V G+CAVRLVKAGA+I+G+NCH DP +K + +M +AV AGLKAH+M+QPL Y TPD + QGFIDLPEFPFALEPR+ TR+DM +YAREA++AGIRYIGGCCG+E YHIRAVAEELA+E G PE S KH +WG GL+MHTKPWVRARA+R+YWEK++P +GRP + + PD WGVT G L Q E T ++ L++ Sbjct: 90 GQQVNEAACDLARQVANEG-DALVAGGVSQTPSYLSCKSETDVKAIFKKQMDVFIKKDVDFLIAEYFEHVEEAEWAVQVLKSTGKPVAASMCIGPKGDMHGVTPGDCAVRLVKAGADIVGVNCHFDPMTCVKTVAMMKAAVEKAGLKAHYMVQPLAYHTPDCNCQGFIDLPEFPFALEPRVLTRWDMQQYAREAFNAGIRYIGGCCGYEPYHIRAVAEELAQERGFLPEASKKHGMWGSGLEMHTKPWVRARARRDYWEKMKPASGRPLCPSMSTPDGWGVTKGDAALMQQKEATTKDQLRPLFE 393
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Cavefish
Match: bhmt (betaine--homocysteine S-methyltransferase 1 [Source:NCBI gene;Acc:103034807]) HSP 1 Score: 409.068 bits (1050), Expect = 3.867e-141 Identity = 186/305 (60.98%), Postives = 236/305 (77.38%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 G +N AAC LA++VA+EG D LV GGVSQTPSYL+ +T+ + IF+KQ VF +++VDFL+ EYFEHVEEAEWAV+ K P+A ++CIGP+GDM+ V G+CAVRLVKAGA+I+G+NCH DP +K + +M +AV AGLKAH+M+QPL Y TPD + QGFIDLPEFPFALEPR+ TR+DM +YAREA++AGIRYIGGCCG+E YHIRAVAEELA+E G PE S KH +WG GL+MHTKPWVRARA+R+YWEK++P +GRP + + PD WGVT G L Q E T ++ L++ Sbjct: 170 GQQVNEAACDLARQVANEG-DALVAGGVSQTPSYLSCKSETDVKAIFKKQMDVFIKKDVDFLIAEYFEHVEEAEWAVQVLKSTGKPVAASMCIGPKGDMHGVTPGDCAVRLVKAGADIVGVNCHFDPMTCVKTVAMMKAAVEKAGLKAHYMVQPLAYHTPDCNCQGFIDLPEFPFALEPRVLTRWDMQQYAREAFNAGIRYIGGCCGYEPYHIRAVAEELAQERGFLPEASKKHGMWGSGLEMHTKPWVRARARRDYWEKMKPASGRPLCPSMSTPDGWGVTKGDAALMQQKEATTKDQLRPLFE 473
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004959.1 (pep scaffold:Pmarinus_7.0:GL478860:9466:10943:1 gene:ENSPMAG00000004502.1 transcript:ENSPMAT00000004959.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 190.66 bits (483), Expect = 8.915e-61 Identity = 86/135 (63.70%), Postives = 106/135 (78.52%), Query Frame = 3 Query: 579 PEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRA-RAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 P P ALEPRICTR++MH+YAREAY G+RYIGGCCGFEAYH+RA+AEELA E GR P S+KHD WG GL MHTKPWVRA RA+++YWEKL P TGRPF+ A + PD WG+T GH +L Q + T + +++ L+ Sbjct: 1 PHAPPALEPRICTRWEMHRYAREAYALGVRYIGGCCGFEAYHVRAMAEELAVERGRLPAASEKHDSWGAGLGMHTKPWVRASRARKDYWEKLEPSTGRPFSCACSHPDSWGITKGHADLVQQTDATTENQLKALF 135
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Nematostella
Match: EDO47743 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLS1]) HSP 1 Score: 421.394 bits (1082), Expect = 1.361e-147 Identity = 196/304 (64.47%), Postives = 240/304 (78.95%), Query Frame = 3 Query: 72 ANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQ 983 A IN AAC LA++VA EG D LV GGV QTP+YL+G GK Q F+KQ VF +++VDF++ EY+EHVEEA WAVE K+ PIA +LCIGPEGDM+ V G+CAVRL +AGA+ IG+NCH P L+ M++M + + AG K H MIQPLGY TPD QGFIDLPEFPF LEPRICTR+DMHKYAREAYD GIR+IGGCCGFE YHIRA++EELAKE G+FP+GS+KH LWG GL+ HTKPWVR+RA+R+YWEKL P +GRPF+A+ + PD WG+TAGHD LKQHAE T D E++++ + Sbjct: 91 AAINEAACDLAREVADEG-DALVAGGVCQTPTYLSGKGKEACQAEFQKQVDVFIKKDVDFIIAEYYEHVEEAVWAVELLKKTGKPIAASLCIGPEGDMHGVSAGDCAVRLAEAGADCIGVNCHYGPIKSLETMRLMKAGLDAAGYKKHLMIQPLGYHTPDCGKQGFIDLPEFPFGLEPRICTRWDMHKYAREAYDMGIRFIGGCCGFEPYHIRALSEELAKERGKFPKGSEKHGLWGDGLRQHTKPWVRSRARRDYWEKLNPSSGRPFSASCSKPDNWGITAGHDYLKQHAEDTSDKELKEIME 393
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Nematostella
Match: EDO48830 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIN7]) HSP 1 Score: 296.975 bits (759), Expect = 4.986e-99 Identity = 147/282 (52.13%), Postives = 184/282 (65.25%), Query Frame = 3 Query: 78 INRAACKLAKKVASEGKDVLVLGGVSQTPS-YLTGIG-KTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVP-DRWGVT 914 I+ A LAK V+ EG+ L G + +T S + G+ K Q FR Q +F + +D ++ EY HV+EAEW VE KE +P A +L I EGD + V GECA+RLV+AGA+IIG+NC DP L + +M A+ GLK H+M+QP+GY PD GF +PE P ALEPR+ TR + HK+AR+AY+ G+RYIGGCCGFE YHIRAVAEELAKE GRFP GSDK LWG L H +P + RA REYWE L P TGRPF+AAYA D W + Sbjct: 81 ISHAGSLLAKGVSGEGEFALASGSLCETGSLFRKGLASKEEIQQRFRDQVQIFVDTGMDLIIAEYISHVQEAEWMVEVIKESGMPTAVSLAISREGDHHGVLPGECALRLVRAGADIIGVNCRFDPERSLDTIALMQEAIQREGLKTHWMVQPVGYWVPDAGPSGFTSIPENPLALEPRLMTRIEAHKFARKAYNMGVRYIGGCCGFEPYHIRAVAEELAKERGRFPPGSDKSCLWGKALVHHAEPQIARRANREYWENLEPATGRPFSAAYATTEDTWKTS 362
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Nematostella
Match: EDO48828 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIN5]) HSP 1 Score: 288.115 bits (736), Expect = 1.517e-95 Identity = 145/287 (50.52%), Postives = 185/287 (64.46%), Query Frame = 3 Query: 75 NINRAACKLAKKVASEGKDVLVLGGVSQTPS-YLTGIG-KTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAV-PDRWGVTAGHD 926 I+ A LAK+V+ EG+ L G + +T S ++ G+ K + FR Q +F + +D L+ EY HV+EAEW VE KE P+A T+ I EGD + V GECAVRLV+AGA+IIG+NC DP L + +M A+ GLK H+M+QPLGY PD GF +PE ALEPR+ TR + HK+AR+AY+ G+RYIGGCCGFE YHIRA+A+EL+KE GR P GSDK LWG L H + V RA REYWEKL P TGRPF+ A+AV D W H+ Sbjct: 88 EISHAGSILAKEVSDEGEFALSSGSLCETGSLFIKGLASKEEIKQRFRDQVKIFVDTGMDLLIAEYISHVQEAEWMVEVMKESGKPVAVTMAISREGDRHGVLPGECAVRLVRAGADIIGVNCRFDPERSLDTIALMQEAIQREGLKTHWMVQPLGYWCPDAGPSGFTSIPECTLALEPRVLTRIEAHKFARKAYNMGVRYIGGCCGFEPYHIRALAKELSKERGRLPPGSDKSCLWGEALVHHAEAQVARRATREYWEKLVPATGRPFSPAFAVHEDTWKTEKKHE 374
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Nematostella
Match: EDO48829 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIN6]) HSP 1 Score: 268.855 bits (686), Expect = 2.819e-87 Identity = 134/264 (50.76%), Postives = 172/264 (65.15%), Query Frame = 3 Query: 78 INRAACKLAKKVASEGKDVLVLGGVSQTPS-YLTGIG-KTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCT 863 I+RA LAK+V+ +G+ L G + +T S ++ G+ K + FR Q +F + +D L+ EY HV+EAEW VE KE P+A T+ I EGD + V GECAVRLV+AGA+IIG+N DP L + +M A+ GLK H+M+QPLGY PD G +PE AL+PR+ TR + HK+AR+AY+ G+RYIGGCCGFE YHIRA+AEELA E GRFP GSDK LWG L HT+P + RA REYWE L P T Sbjct: 95 ISRAGSILAKEVSDKGEFALSSGSLCETGSLFIKGLATKEEIKQRFRDQVKIFVDTGMDLLIAEYISHVQEAEWMVEVMKESGKPVAVTMAISREGDRHGVLPGECAVRLVRAGADIIGVNYRFDPERSLDTIALMQEAIQREGLKTHWMVQPLGYWCPDAGPSGITSIPECSLALDPRVLTRIEAHKFARKAYNMGVRYIGGCCGFEPYHIRALAEELANERGRFPPGSDKSCLWGKALVHHTEPQIARRANREYWENLVPAT 358
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Medaka
Match: ENSORLT00000004116.2 (betaine--homocysteine S-methyltransferase 1 [Source:NCBI gene;Acc:101157623]) HSP 1 Score: 413.69 bits (1062), Expect = 1.679e-144 Identity = 196/304 (64.47%), Postives = 234/304 (76.97%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 GA IN AAC LA++VA+EG D LV GGVSQTPSYL+ + + + IF+KQ VF ++ VDFL+ EYFEHVEEA WAVE KE P+A TLCIGP+GDM+ V ECAVRLV AGA I+GINCH DP +K +K+M V AGLKAH+M+QPL + TPD + QGFIDLPEFPF LEPRI TR+DMHKYAREAY+AGIRYIGGCCGFE YHIRAVAEELA E G FP ++KH WG GL+MHTKPWVRARA+R+YWE L+P +GRPF + +VPD WGVT GH EL Q E T ++++L+ Sbjct: 62 GAQINEAACDLAREVANEG-DALVAGGVSQTPSYLSCKSEKDVKAIFKKQLDVFVKKNVDFLIAEYFEHVEEAVWAVEMLKETGKPVAATLCIGPQGDMHGVSPQECAVRLVTAGAQIVGINCHFDPETCVKTVKMMKEGVEKAGLKAHYMVQPLAFHTPDCNCQGFIDLPEFPFGLEPRILTRWDMHKYAREAYNAGIRYIGGCCGFEPYHIRAVAEELATERGFFPAATEKHGPWGSGLEMHTKPWVRARARRDYWENLKPSSGRPFCPSLSVPDGWGVTRGHAELMQQKEATSKDQLKQLF 364
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Medaka
Match: bhmt (betaine--homocysteine S-methyltransferase 1-like [Source:NCBI gene;Acc:101175580]) HSP 1 Score: 405.216 bits (1040), Expect = 1.053e-140 Identity = 190/304 (62.50%), Postives = 232/304 (76.32%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLY 980 G IN AAC LA++VA+EG D LV GGVSQTPSY++ + + IF+KQ VF ++VDFL+ EYFEHVEEAEWAV+ K P+A TLCIGPEGD+N V G+CAVRLVKAGA+I+G+NCH DP +K +K+M V AGLKAH+M QPL TPD + QGFIDLPEFPFALEPR+ TR+DMH+YAR AY+AGIRYIGGCCGFE YHIRAVAEELA E G P S+KH WG GL+MHTKPWVRARA+REYWE L+P +GRPF AA + PD WG++ GH +L Q E T + +++ ++ Sbjct: 91 GQQINEAACDLAREVANEG-DALVAGGVSQTPSYMSCESEQAVKAIFKKQIDVFIRKDVDFLIAEYFEHVEEAEWAVQILKTSGKPVAATLCIGPEGDLNGVSPGDCAVRLVKAGADIVGVNCHFDPETCVKTVKLMKEGVERAGLKAHYMSQPLALHTPDCNRQGFIDLPEFPFALEPRVLTRWDMHRYARGAYNAGIRYIGGCCGFEPYHIRAVAEELAPERGFLPPASEKHGSWGAGLEMHTKPWVRARARREYWETLKPASGRPFCAAMSKPDCWGISRGHADLMQTKEATSEAQLKAVF 393
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Planmine SMEST
Match: SMESG000019342.1 (SMESG000019342.1) HSP 1 Score: 654.825 bits (1688), Expect = 0.000e+0 Identity = 311/311 (100.00%), Postives = 311/311 (100.00%), Query Frame = 3 Query: 69 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQHMMKMK 1001 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQHMMKMK Sbjct: 92 GANINRAACKLAKKVASEGKDVLVLGGVSQTPSYLTGIGKTNTQNIFRKQFTVFKEEEVDFLLCEYFEHVEEAEWAVETAKEFNLPIACTLCIGPEGDMNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAHFMIQPLGYMTPDNSNQGFIDLPEFPFALEPRICTRFDMHKYAREAYDAGIRYIGGCCGFEAYHIRAVAEELAKEHGRFPEGSDKHDLWGGGLKMHTKPWVRARAKREYWEKLRPCTGRPFAAAYAVPDRWGVTAGHDELKQHAEMTDDIEIEKLYQHMMKMK 402 The following BLAST results are available for this feature:
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 4
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 2
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 3
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 2
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 1
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 2
BLAST of Betaine--homocysteine S-methyltransferase 1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 1
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035725 ID=SMED30035725|Name=Betaine--homocysteine S-methyltransferase 1|organism=Schmidtea mediterranea sexual|type=transcript|length=1042bpback to top protein sequence of SMED30035725-orf-1 >SMED30035725-orf-1 ID=SMED30035725-orf-1|Name=SMED30035725-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=214bp MNNVPTGECAVRLVKAGANIIGINCHNDPFIVLKAMKIMISAVHDAGLKAback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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