Synaptotagmin XV-like protein

Overview


Name	Synaptotagmin XV-like protein
Smed ID	SMED30035718
Length (bp)	1737

Neoblast Clusters

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Synaptotagmin XV-like protein (SMED30035718) t-SNE clustered cells

Violin plots show distribution of expression levels for Synaptotagmin XV-like protein (SMED30035718) in cells (dots) of each of the 12 neoblast clusters.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035718

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 26

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30035718	h1SMcG0019330	Contig3128	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30035718	h1SMcG0021425	Contig3128	GPL15192	PMID:23079596 Forsthoefel et al., 2012
X1 cell	SMED30035718	h1SMcG0019330	SmedASXL_000972	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30035718	h1SMcG0019330	SmedASXL_000972	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30035718	h1SMcG0019330	SmedASXL_012503	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
oocyte	SMED30035718	h1SMcG0019330	KY847533.1	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
ovary	SMED30035718	h1SMcG0019330	KY847533.1	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	KY847533.1	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
ovary	SMED30035718	h1SMcG0019330	PL04017B1F10	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	PL04017B1F10	smed_ncbi_20240424	PMID:28434803 Rouhana et al., 2017
oocyte	SMED30035718	h1SMcG0019330	Contig38054	newmark_ests	PMID:28434803 Rouhana et al., 2017
oocyte	SMED30035718	h1SMcG0019330	Contig38054	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
ovary	SMED30035718	h1SMcG0019330	Contig38054	newmark_ests	PMID:28434803 Rouhana et al., 2017
ovary	SMED30035718	h1SMcG0019330	Contig38054	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	Contig38054	newmark_ests	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	Contig38054	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	Contig38054	newmark_ests	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	Contig38054	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30035718	h1SMcG0019330	Contig38054	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30035718	h1SMcG0019330	Contig38054	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
ovary	SMED30035718	h1SMcG0019330	Contig3128	GPL15192	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0019330	Contig3128	GPL15192	PMID:28434803 Rouhana et al., 2017
ovary	SMED30035718	h1SMcG0021425	Contig3128	GPL15192	PMID:28434803 Rouhana et al., 2017
vitelline gland	SMED30035718	h1SMcG0021425	Contig3128	GPL15192	PMID:28434803 Rouhana et al., 2017
neoblast	SMED30035718	h1SMcG0019330	SMED_06192_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30035718	h1SMcG0019330	SMED_06192_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077728)

HSP 1 Score: 50.447 bits (119), Expect = 3.788e-6
Identity = 74/294 (25.17%), Postives = 123/294 (41.84%), Query Frame = 2

Query:  785 KYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNI--TSLLLKECILQMIVKEETPKFLEKNIVLGCVDFAL---DEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV------NVKELLPGPEQVSDVSVEL-FLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCL--INSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISA 1624
            K G++ F L YD+ S +L VTV  A+ L        +  YVKV L                +PDK         K  F T +     +PVFNETF F ++     + K  +  +    +  +F  K+  +G V   L   D AQ I++   L  +  +    G  E  G +  SL+Y      LTV      N+K++  G   +SD  V++  +++   +   +       L    +E+F  +     I  +CLV+      R  +  P+GR ++G +   +G  L  W+++ A
Sbjct:  190 KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYL----------------LPDK---------KKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIF---DFDRF-SKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGE----GGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG--GLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCM--GTGTELRHWSDMLA 446

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BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0345331)

HSP 1 Score: 50.447 bits (119), Expect = 3.788e-6
Identity = 74/294 (25.17%), Postives = 123/294 (41.84%), Query Frame = 2

Query:  785 KYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNI--TSLLLKECILQMIVKEETPKFLEKNIVLGCVDFAL---DEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV------NVKELLPGPEQVSDVSVEL-FLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCL--INSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISA 1624
            K G++ F L YD+ S +L VTV  A+ L        +  YVKV L                +PDK         K  F T +     +PVFNETF F ++     + K  +  +    +  +F  K+  +G V   L   D AQ I++   L  +  +    G  E  G +  SL+Y      LTV      N+K++  G   +SD  V++  +++   +   +       L    +E+F  +     I  +CLV+      R  +  P+GR ++G +   +G  L  W+++ A
Sbjct:  190 KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYL----------------LPDK---------KKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIF---DFDRF-SKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGE----GGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG--GLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCM--GTGTELRHWSDMLA 446

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BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077727)

HSP 1 Score: 50.447 bits (119), Expect = 3.788e-6
Identity = 74/294 (25.17%), Postives = 123/294 (41.84%), Query Frame = 2

Query:  785 KYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNI--TSLLLKECILQMIVKEETPKFLEKNIVLGCVDFAL---DEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV------NVKELLPGPEQVSDVSVEL-FLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCL--INSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISA 1624
            K G++ F L YD+ S +L VTV  A+ L        +  YVKV L                +PDK         K  F T +     +PVFNETF F ++     + K  +  +    +  +F  K+  +G V   L   D AQ I++   L  +  +    G  E  G +  SL+Y      LTV      N+K++  G   +SD  V++  +++   +   +       L    +E+F  +     I  +CLV+      R  +  P+GR ++G +   +G  L  W+++ A
Sbjct:  190 KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYL----------------LPDK---------KKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIF---DFDRF-SKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGE----GGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG--GLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCM--GTGTELRHWSDMLA 446

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BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0077726)

HSP 1 Score: 50.0618 bits (118), Expect = 3.866e-6
Identity = 74/294 (25.17%), Postives = 123/294 (41.84%), Query Frame = 2

Query:  785 KYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNI--TSLLLKECILQMIVKEETPKFLEKNIVLGCVDFAL---DEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV------NVKELLPGPEQVSDVSVEL-FLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCL--INSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISA 1624
            K G++ F L YD+ S +L VTV  A+ L        +  YVKV L                +PDK         K  F T +     +PVFNETF F ++     + K  +  +    +  +F  K+  +G V   L   D AQ I++   L  +  +    G  E  G +  SL+Y      LTV      N+K++  G   +SD  V++  +++   +   +       L    +E+F  +     I  +CLV+      R  +  P+GR ++G +   +G  L  W+++ A
Sbjct:  192 KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYL----------------LPDK---------KKKFETKVHRKTLSPVFNETFTFKSLPYADAMNKTLVFAIF---DFDRF-SKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGE----GGQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG--GLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCM--GTGTELRHWSDMLA 448

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BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
Match: Syt1 (gene:FBgn0004242 transcript:FBtr0332218)

HSP 1 Score: 49.6766 bits (117), Expect = 5.317e-6
Identity = 71/305 (23.28%), Postives = 117/305 (38.36%), Query Frame = 2

Query:  785 KYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEI---------------IRDIKPI-GQIEDKGKVILSLQYNRQLTVLTV------NVKELLPGPEQVSDVSVEL-FLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCL--INSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISA 1624
            K G++ F L YD+ S +L VTV  A+ L        +  YVKV L                +PDK         K  F T +     +PVFNETF F ++                     + K +V    DF         KH+ + E+                RD+  + G+    G +  SL+Y      LTV      N+K++  G   +SD  V++  +++   +   +       L    +E+F  +     I  +CLV+      R  +  P+GR ++G +   +G  L  W+++ A
Sbjct:  192 KLGRLNFKLEYDFNSNSLAVTVIQAEELPALDMGGTSDPYVKVYL----------------LPDK---------KKKFETKVHRKTLSPVFNETFTFKSLPYA----------------DAMNKTLVFAIFDF-----DRFSKHDQIGEVKVPLCTIDLAQTIEEWRDLVSVEGEGGQLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVG--GLSDPYVKIAIMQNGKRLKKKKTSIKKCTLNPYYNESFSFEVPFEQIQKICLVVTVVDYDRIGTSEPIGRCILGCM--GTGTELRHWSDMLA 446

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BLAST of Synaptotagmin XV-like protein vs. Ensembl Mouse
Match: Syt15 (synaptotagmin XV [Source:MGI Symbol;Acc:MGI:2442166])

HSP 1 Score: 52.373 bits (124), Expect = 1.012e-6
Identity = 61/221 (27.60%), Postives = 96/221 (43.44%), Query Frame = 2

Query: 1016 FRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDI--KPIGQIEDKGKVILSLQYNRQLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKL----ELDSNLKSGN-----SENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVK 1645
             ++  K   CNP F+E F F  ++S  + + +L+  V     K   K+ +LG V F L    L   H  +  I RD+  K +    + G +   L YN  L+ LTV V  L     Q+ +    + +    S+M   K        + L S N     + +F +D+  +++  L LV          +PLGR+VVGP  +  G  L  W E+    +E VK
Sbjct:  194 LQSKTKHKICNPQFDENFIF-QVSSKSVTQRVLKFSVYHVNKK--RKHQLLGQVLFPLKNETLAGDHHRI--IWRDLEAKNLEPPSEFGDIQFCLSYNDYLSRLTVVV--LRAKGLQLQEDRSVVSVFVKVSLMNHNKFVKCKRTSAVLGSVNPVYNETFSFKVDTNELDTASLSLVVLQTTEGNKSSPLGRVVVGPYMYTRGKELEHWGEMLRKPKELVK 407

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BLAST of Synaptotagmin XV-like protein vs. UniProt/SwissProt
Match: sp|Q8C6N3|SYT15_MOUSE (Synaptotagmin-15 OS=Mus musculus OX=10090 GN=Syt15 PE=2 SV=1)

HSP 1 Score: 52.373 bits (124), Expect = 7.079e-6
Identity = 61/221 (27.60%), Postives = 96/221 (43.44%), Query Frame = 2

Query: 1016 FRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDI--KPIGQIEDKGKVILSLQYNRQLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKL----ELDSNLKSGN-----SENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVK 1645
             ++  K   CNP F+E F F  ++S  + + +L+  V     K   K+ +LG V F L    L   H  +  I RD+  K +    + G +   L YN  L+ LTV V  L     Q+ +    + +    S+M   K        + L S N     + +F +D+  +++  L LV          +PLGR+VVGP  +  G  L  W E+    +E VK
Sbjct:  194 LQSKTKHKICNPQFDENFIF-QVSSKSVTQRVLKFSVYHVNKK--RKHQLLGQVLFPLKNETLAGDHHRI--IWRDLEAKNLEPPSEFGDIQFCLSYNDYLSRLTVVV--LRAKGLQLQEDRSVVSVFVKVSLMNHNKFVKCKRTSAVLGSVNPVYNETFSFKVDTNELDTASLSLVVLQTTEGNKSSPLGRVVVGPYMYTRGKELEHWGEMLRKPKELVK 407

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BLAST of Synaptotagmin XV-like protein vs. TrEMBL
Match: A0A1W6I193 (Synaptotagmin XV-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 467.618 bits (1202), Expect = 8.308e-161
Identity = 229/234 (97.86%), Postives = 230/234 (98.29%), Query Frame = 2

Query:  653 MPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVNVKELLPGP 1354
            MPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGV DKNINKFQKSLKGSFRTAIKSDFCNPVF+ETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV VKELL  P
Sbjct:    1 MPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVLDKNINKFQKSLKGSFRTAIKSDFCNPVFDETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVYVKELLSWP 234

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BLAST of Synaptotagmin XV-like protein vs. TrEMBL
Match: A0A1S3STL1 (synaptotagmin-like protein 4 isoform X1 OS=Salmo salar OX=8030 GN=LOC106611707 PE=4 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.250e-6
Identity = 57/191 (29.84%), Postives = 91/191 (47.64%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQ---IEDKGKVILSLQY 1300
            SIY++   +   E+S  G I+FSL YD  + +L V V   + L  G  T+++++ YVK  L                +PDK       S  G  +T+IK +  +P +NET KF+   S +L    LQ+ V       L +N  LG V+  LD   L  +HE    ++    P+      + KG++++SL+Y
Sbjct:  375 SIYSEAGDYDCVEVS--GDIVFSLSYDDTTHSLAVLVKECRSLAHGDATRQRSNPYVKCYL----------------LPDK-------SRTGKKKTSIKRNTVDPTYNETLKFSISRSQVLTRS-LQLSVWHH--DRLGRNAFLGEVEVPLDCRDLDSQHEECVALMGKASPLQSSAFSQYKGELVISLKY 537

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BLAST of Synaptotagmin XV-like protein vs. TrEMBL
Match: A0A1S3STK4 (synaptotagmin-like protein 4 isoform X2 OS=Salmo salar OX=8030 GN=LOC106611707 PE=4 SV=1)

HSP 1 Score: 63.1586 bits (152), Expect = 1.289e-6
Identity = 57/191 (29.84%), Postives = 91/191 (47.64%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQ---IEDKGKVILSLQY 1300
            SIY++   +   E+S  G I+FSL YD  + +L V V   + L  G  T+++++ YVK  L                +PDK       S  G  +T+IK +  +P +NET KF+   S +L    LQ+ V       L +N  LG V+  LD   L  +HE    ++    P+      + KG++++SL+Y
Sbjct:  370 SIYSEAGDYDCVEVS--GDIVFSLSYDDTTHSLAVLVKECRSLAHGDATRQRSNPYVKCYL----------------LPDK-------SRTGKKKTSIKRNTVDPTYNETLKFSISRSQVLTRS-LQLSVWHH--DRLGRNAFLGEVEVPLDCRDLDSQHEECVALMGKASPLQSSAFSQYKGELVISLKY 532

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BLAST of Synaptotagmin XV-like protein vs. TrEMBL
Match: A0A4W5PF13 (Synaptotagmin-like 4 OS=Hucho hucho OX=62062 PE=4 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 2.015e-6
Identity = 58/191 (30.37%), Postives = 90/191 (47.12%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQ---IEDKGKVILSLQY 1300
            SIY++   +   E+S  G I+FSL YD  + +L V V     L  G  T+++++ YVK  L                +PDK       S  G  +T+IK +  +P +NET KF+   S +L    LQ+ V       L +N  LG V+  LD   L D HE    ++    P+      + KG++++SL+Y
Sbjct:  376 SIYSEAGDYDCVEVS--GDIVFSLSYDDTTHSLAVLVKECHSLAHGDATRQRSNPYVKCYL----------------LPDK-------SRTGKKKTSIKRNTVDPTYNETLKFSISRSQVLTRS-LQLSVWHH--DRLGRNAFLGEVEVPLDCRDLNDLHEECVALMGKASPLQSSAFSQYKGELVISLKY 538

[Close]

BLAST of Synaptotagmin XV-like protein vs. TrEMBL
Match: A0A1S3STL3 (synaptotagmin-like protein 4 isoform X3 OS=Salmo salar OX=8030 GN=LOC106611707 PE=4 SV=1)

HSP 1 Score: 62.3882 bits (150), Expect = 2.393e-6
Identity = 57/191 (29.84%), Postives = 91/191 (47.64%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQ---IEDKGKVILSLQY 1300
            SIY++   +   E+S  G I+FSL YD  + +L V V   + L  G  T+++++ YVK  L                +PDK       S  G  +T+IK +  +P +NET KF+   S +L    LQ+ V       L +N  LG V+  LD   L  +HE    ++    P+      + KG++++SL+Y
Sbjct:  323 SIYSEAGDYDCVEVS--GDIVFSLSYDDTTHSLAVLVKECRSLAHGDATRQRSNPYVKCYL----------------LPDK-------SRTGKKKTSIKRNTVDPTYNETLKFSISRSQVLTRS-LQLSVWHH--DRLGRNAFLGEVEVPLDCRDLDSQHEECVALMGKASPLQSSAFSQYKGELVISLKY 485

[Close]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Cavefish
Match: syt15 (synaptotagmin XV [Source:ZFIN;Acc:ZDB-GENE-090527-2])

HSP 1 Score: 50.447 bits (119), Expect = 3.656e-6
Identity = 65/254 (25.59%), Postives = 113/254 (44.49%), Query Frame = 2

Query:  932 CPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEII-RDIKPIG--QIEDKGKVILSLQYNRQLTVLTVNVKELLPGPEQVSD---VSVELFLRSIDSIMYSRKLELDSNLKSGNSE--NFDLDSCLINSVCLVLVFYARI----RNCSRTP-------LGRLVVGPIQFASGARLAQWTEISAGNEE 1636
            C   T+   L  +P ++  + Q   +G          C P FN++F F  ++++ + +C L M V   +   L+K+  +G V F L   +L D  E+  +++ RD++      +   G + +SL YN+ L  LTV V  L     Q S    V V++ L+    ++ ++   +    +   +E   F L    +++ CL L            C  TP       LG +V+GP  +A G  L  WTE++ G +E
Sbjct:  170 CQACTTLIKLQLLPSEDRRQRQAKARG--------KGCQPQFNDSFVF-QVSNISVGQCTLSMSVY--SVDRLKKHHTVGRVLFPL---RLSDLREAAGKVLWRDLETESDLALSKHGDIQVSLNYNQSLQRLTVVV--LRARGLQCSSNAGVCVQVSLQIHTQVVKTKWTSVAKGSEPIFNEKLTFRLHPRQLDTTCLSLEVQQPATEEPSECQPTPRTTAPMSLGVVVIGPFMYARGRELEHWTEMALGIDE 407

[Close]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Cavefish
Match: sytl4 (synaptotagmin like 4 [Source:NCBI gene;Acc:103045066])

HSP 1 Score: 49.6766 bits (117), Expect = 8.278e-6
Identity = 54/192 (28.12%), Postives = 87/192 (45.31%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESL----NEIIRDIKPIGQIEDKGKVILSLQY 1300
            S+Y++   + I ++S  G+I+FSL+YD  +++L V V   + L      K+K + YVK  L                +PDK       S +   +TA KS   NP +NET K++   S L+    LQ+ V         +N  LG V   LD   +   HE       +    + P    + KG++++SL+Y
Sbjct:  398 SVYSEAGDYDIVDVS--GEIVFSLHYDETAQSLAVMVKECRGLAYADAAKKKCNPYVKSYL----------------LPDK-------SRQSKKKTATKSKTINPTYNETLKYSISRSQLMTR-TLQLSVWHY--DRFGRNAFLGEVQLPLDCHDIDSAHEECVILRGKAAGSLAPSAFAQYKGELVISLKY 561

[Close]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006493.1 (pep scaffold:Pmarinus_7.0:GL476457:113922:122135:1 gene:ENSPMAG00000005868.1 transcript:ENSPMAT00000006493.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 46.9802 bits (110), Expect = 1.965e-6
Identity = 51/176 (28.98%), Postives = 76/176 (43.18%), Query Frame = 2

Query:  791 GQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQL---IDKHESLN-EIIRDIKPIGQIED--KGKVILSLQY 1300
            G I FS+ YD+    L +T+   + L  +G +R           TK C  Y     L   PDK       S +G  +T IK +  NPVFNET K+    + L   C+   +   ++      N  LG     LD   L    D+  +L   + R+  P   I +  KG++IL+L+Y
Sbjct:    3 GDINFSVSYDYRVGVLSLTLRQCRNL-AYGEER-----------TKRCDPYVKVYLL---PDK-------SRQGKRKTKIKKNTINPVFNETLKYAISHTQLEVRCVHLSVWHHDS---FRHNSFLGQASLPLDCCDLERGDDRWCALQPRVTRN--PFAAINNKYKGELILALKY 151

[Close]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Nematostella
Match: EDO33088 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST77])

HSP 1 Score: 48.9062 bits (115), Expect = 2.280e-6
Identity = 55/212 (25.94%), Postives = 96/212 (45.28%), Query Frame = 2

Query: 1007 KGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLEL--------DSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEI 1618
            K    + +K    +P F+ETF F  + +  +KE  L+  V + T   L K   +G   F+L    L    +    + R IKP  Q+ ++G++ LSL YN   + L V V++     +       E F++ I  I  +RK++         D++    +  +F++ +  ++  CLVL           T +GR+V+GP  F SG   + W  +
Sbjct:   60 KPVLESYVKQSTWDPNFDETFVF-KLNTNEVKEKTLRFSVYDCT--RLHKLCPIGHTLFSLKGQDL----DGTMAVERAIKPQCQV-NRGEISLSLTYNPGTSRLVVGVRQARNILQFEGHAHKEYFVK-ISRIHLNRKVKTKRTPSTDGDASPIFKHDMSFNIPTEQLSDSCLVLSLMNHGVVRGSTTIGRVVLGPYVFGSGNERSHWGRM 262

[Close]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Medaka
Match: sytl4 (synaptotagmin like 4 [Source:NCBI gene;Acc:101163586])

HSP 1 Score: 60.077 bits (144), Expect = 5.012e-9
Identity = 57/207 (27.54%), Postives = 95/207 (45.89%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHES----LNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVNVKELL 1345
            SIY+D   +   E+S  GQ++F+L YD  +++L+V +   + L  G  +++ ++ YVK  L             L G   +N  K          T+IK +  NPVF+ET K++   S LL + +   +        L +N+ LG V   LD A L   HE     + ++  D+         G++++SL+Y       T  VK +L
Sbjct:  375 SIYSDAGDYGTVEVS--GQVVFALRYDEHTQSLQVFIKECQGLAHGDASRKLSNPYVKCYL-------------LHGKTRQNKKK----------TSIKKNTINPVFSETLKYSMSRSELLGQSVSISVWHHGR---LSRNVFLGEVTIPLDSANLDTPHEECLHLMGKMSSDVPDAAFERCSGELVISLKYVPPNKTTTEKVKGIL 553

[Close]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Medaka
Match: sytl4 (synaptotagmin like 4 [Source:NCBI gene;Acc:101163586])

HSP 1 Score: 59.6918 bits (143), Expect = 5.364e-9
Identity = 53/192 (27.60%), Postives = 90/192 (46.88%), Query Frame = 2

Query:  740 SIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLM-GFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHES----LNEIIRDIKPIGQIEDKGKVILSLQY 1300
            SIY+D   +   E+S  GQ++F+L YD  +++L+V +   + L  G  +++ ++ YVK  L             L G   +N  K          T+IK +  NPVF+ET K++   S LL + +   +        L +N+ LG V   LD A L   HE     + ++  D+         G++++SL+Y
Sbjct:  375 SIYSDAGDYGTVEVS--GQVVFALRYDEHTQSLQVFIKECQGLAHGDASRKLSNPYVKCYL-------------LHGKTRQNKKK----------TSIKKNTINPVFSETLKYSMSRSELLGQSVSISVWHH---GRLSRNVFLGEVTIPLDSANLDTPHEECLHLMGKMSSDVPDAAFERCSGELVISLKY 538

[Close]

BLAST of Synaptotagmin XV-like protein vs. Planmine SMEST
Match: SMESG000066997.1 (SMESG000066997.1)

HSP 1 Score: 1017.3 bits (2629), Expect = 0.000e+0
Identity = 504/521 (96.74%), Postives = 506/521 (97.12%), Query Frame = 2

Query:   98 MINLIFYLLLFGIAGFCNCSPIQELQINNDNIIPLIIGISLMGFVIIILLASLCVCFIINKTSPDKKTADGKKAPPENIKLLDFVHKNSMELIEDKNEINKRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSLEASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVKMHEII 1660
            MINLIFYLLLFGIAGFCNCSPIQELQINNDNIIPLIIGISLMGFVIIILLASLCVCFIINKTSPDKKTADGKKAPPENIKLLDFVHKNSMELIEDKNEINKRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSLEASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEIS              +KTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVF+ETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV VKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVKMHEII
Sbjct:    1 MINLIFYLLLFGIAGFCNCSPIQELQINNDNIIPLIIGISLMGFVIIILLASLCVCFIINKTSPDKKTADGKKAPPENIKLLDFVHKNSMELIEDKNEINKRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSLEASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEIS--------------NKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFDETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVYVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVKMHEII 507

[Close]

BLAST of Synaptotagmin XV-like protein vs. Planmine SMEST
Match: SMESG000066997.1 (SMESG000066997.1)

HSP 1 Score: 838.18 bits (2164), Expect = 0.000e+0
Identity = 415/432 (96.06%), Postives = 417/432 (96.53%), Query Frame = 2

Query:  365 MELIEDKNEINKRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSLEASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVKMHEII 1660
            MELIEDKNEINKRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSLEASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEIS              +KTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVF+ETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTV VKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVKMHEII
Sbjct:    1 MELIEDKNEINKRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSLEASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQNSNDKDFERRTTKKYSIYNDNDFFPIKEIS--------------NKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFDETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNRQLTVLTVYVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTEISAGNEESVKMHEII 418

[Close]

BLAST of Synaptotagmin XV-like protein vs. Planmine SMEST
Match: SMESG000036721.1 (SMESG000036721.1)

HSP 1 Score: 58.151 bits (139), Expect = 1.053e-8
Identity = 84/321 (26.17%), Postives = 138/321 (42.99%), Query Frame = 2

Query:  764 FPIKEISKYGQIIFSLYYDWISKTLEVTVNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQKSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIK-PIGQIEDKGKVILSLQYNRQLT--VLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSN--LKSGNS---------------ENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASG-ARLAQWTE-ISAGNEESVKMHEII 1660
            + I  +   G++ FS+ Y+     L VT+N A YL    T     FYVKV L                +  +N  K Q   K    TA K    NP+F +TF F  +T   L    LQ  VK+   K ++KN  LG   F LD  ++I+  E   E+ RD++  + +   +G++++SL Y+   +   L+VN+             +  L +R  D+ +++R   L  N  +K+  S                 F++D   I  V +V+   +R +      LG+L++G + +    + L  W + IS  N    K H I+
Sbjct:  169 YEILNLYGQGKLCFSIVYNEHISRLYVTINKAVYLNSSKTNNLAGFYVKVYL----------------LNTENDMKLQMH-KSEIVTANK----NPMFEQTFSFL-LTKSSLVSIKLQFKVKQAHIK-VKKNEYLGGFMFHLDNNEIINNPELFQELWRDLRGDLRKDTRRGEILISLMYSEHQSSAFLSVNLHR-----------AKNLQIRQHDNSVFARCTMLVGNKPIKTKRSITVKQDISAPYVDLESVFNVDKLNIMEVGVVIHICSRSKIGFSHLLGKLILGSVMYTDDKSVLIHWKDMISYQNRTVTKWHTIM 455

[Close]

BLAST of Synaptotagmin XV-like protein vs. Planmine SMEST
Match: SMESG000058817.1 (SMESG000058817.1)

HSP 1 Score: 54.299 bits (129), Expect = 1.798e-7
Identity = 60/215 (27.91%), Postives = 102/215 (47.44%), Query Frame = 2

Query: 1019 RTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKFLEKNIVLGCVDFAL-----DEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQYNR----QLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLKSGNSEN-------FDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGARLAQWTE 1615
            R++  +   NP+FN+TF F +ITS+  +   LQ+ VKE   + LE N V+G V F L     D   +I   E   EI  + K   +   +G V+++L+ +     ++ V     + L+   + +S V V   L     ++ ++K +      S  S N        + D  +++  C++L F +R R      +GR ++G IQ+  G  L QWTE
Sbjct:  255 RSSCVTSMGNPMFNQTFTF-HITSIPQQ---LQLTVKE--VRKLESNRVIGYVWFDLSCMLKDNRAMITSQEISREIFGENKLYCR---RGDVLVNLKVSANDSIEINVCVAEARNLIVRNQNIS-VYVRASLLIKHKVVQTKKGQPVKRSISSPSFNDRFKFVITNKDISILDECCIILCFCSRSRVRFSHLIGRCIIGNIQYTEGEGLLQWTE 459

The following BLAST results are available for this feature:

BLAST of Synaptotagmin XV-like protein vs. Ensembl Human
BLAST of Synaptotagmin XV-like protein vs. Ensembl Celegans
BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
BLAST of Synaptotagmin XV-like protein vs. Ensembl Zebrafish
BLAST of Synaptotagmin XV-like protein vs. Ensembl Xenopus
BLAST of Synaptotagmin XV-like protein vs. Ensembl Mouse
BLAST of Synaptotagmin XV-like protein vs. UniProt/SwissProt
BLAST of Synaptotagmin XV-like protein vs. TrEMBL
BLAST of Synaptotagmin XV-like protein vs. Ensembl Cavefish
BLAST of Synaptotagmin XV-like protein vs. Ensembl Sea Lamprey
BLAST of Synaptotagmin XV-like protein vs. Ensembl Yeast
BLAST of Synaptotagmin XV-like protein vs. Ensembl Nematostella
BLAST of Synaptotagmin XV-like protein vs. Ensembl Medaka
BLAST of Synaptotagmin XV-like protein vs. Planmine SMEST

BLAST of Synaptotagmin XV-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Synaptotagmin XV-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Synaptotagmin XV-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Syt1	3.788e-6	25.17	gene:FBgn0004242 transcript:FBtr0077728	[more]
Syt1	3.788e-6	25.17	gene:FBgn0004242 transcript:FBtr0345331	[more]
Syt1	3.788e-6	25.17	gene:FBgn0004242 transcript:FBtr0077727	[more]
Syt1	3.866e-6	25.17	gene:FBgn0004242 transcript:FBtr0077726	[more]
Syt1	5.317e-6	23.28	gene:FBgn0004242 transcript:FBtr0332218	[more]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Synaptotagmin XV-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Synaptotagmin XV-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1


Match Name	E-value	Identity	Description
Syt15	1.012e-6	27.60	synaptotagmin XV [Source:MGI Symbol;Acc:MGI:244216...	[more]

BLAST of Synaptotagmin XV-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 1


Match Name	E-value	Identity	Description
sp\|Q8C6N3\|SYT15_MOUSE	7.079e-6	27.60	Synaptotagmin-15 OS=Mus musculus OX=10090 GN=Syt15...	[more]

BLAST of Synaptotagmin XV-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1W6I193	8.308e-161	97.86	Synaptotagmin XV-like protein OS=Schmidtea mediter...	[more]
A0A1S3STL1	1.250e-6	29.84	synaptotagmin-like protein 4 isoform X1 OS=Salmo s...	[more]
A0A1S3STK4	1.289e-6	29.84	synaptotagmin-like protein 4 isoform X2 OS=Salmo s...	[more]
A0A4W5PF13	2.015e-6	30.37	Synaptotagmin-like 4 OS=Hucho hucho OX=62062 PE=4 ...	[more]
A0A1S3STL3	2.393e-6	29.84	synaptotagmin-like protein 4 isoform X3 OS=Salmo s...	[more]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2


Match Name	E-value	Identity	Description
syt15	3.656e-6	25.59	synaptotagmin XV [Source:ZFIN;Acc:ZDB-GENE-090527-...	[more]
sytl4	8.278e-6	28.13	synaptotagmin like 4 [Source:NCBI gene;Acc:1030450...	[more]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000006493.1	1.965e-6	28.98	pep scaffold:Pmarinus_7.0:GL476457:113922:122135:1...	[more]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Synaptotagmin XV-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO33088	2.280e-6	25.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Synaptotagmin XV-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 2


Match Name	E-value	Identity	Description
sytl4	5.012e-9	27.54	synaptotagmin like 4 [Source:NCBI gene;Acc:1011635...	[more]
sytl4	5.364e-9	27.60	synaptotagmin like 4 [Source:NCBI gene;Acc:1011635...	[more]

BLAST of Synaptotagmin XV-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4


Match Name	E-value	Identity	Description
SMESG000066997.1	0.000e+0	96.74	SMESG000066997.1	[more]
SMESG000066997.1	0.000e+0	96.06	SMESG000066997.1	[more]
SMESG000036721.1	1.053e-8	26.17	SMESG000036721.1	[more]
SMESG000058817.1	1.798e-7	27.91	SMESG000058817.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30035718 ID=SMED30035718|Name=Synaptotagmin XV-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1737bp
GTGATTGTGTGCCTCGAAATCCTTCATTGCCATTGGATATTAGGACTCGA
AATTCAGTTAAAGTGTGCGCACACATATTTCAACTGTAACTGTTACAATG
ATCAACCTGATATTTTATCTACTTCTATTTGGAATTGCTGGATTTTGCAA
TTGTTCGCCGATTCAAGAGTTACAAATAAACAACGATAATATTATACCAT
TAATTATCGGTATAAGCCTAATGGGATTTGTTATTATCATATTATTGGCC
TCGTTGTGTGTTTGTTTCATTATTAACAAGACTTCTCCAGACAAAAAAAC
AGCTGATGGTAAAAAAGCTCCGCCGGAAAACATAAAATTATTAGATTTTG
TTCATAAAAATTCAATGGAATTGATTGAGGATAAAAATGAAATAAACAAA
CGAACTGTAGAAAATAGTGAAAAATCGATACATAATTTGGAAAAGTTTCC
AAACAAGTCTATAATAGAATTTTCTAAAATTCATCGCTATAGGCGAGCAA
GTGTTCCTGCTGTTTTATCAACTTTGCACGAAGCTTCTCCGTCTTTGGAA
GCGAGTAGTAGAAAAATGTCACTGTCATACAACTGTGTCCATGAGCCCCA
ATATGATACCAAAAGGAATACAATAGCACACATTGATACTGATGATACTA
TAATGCCAGAGAGTGGGCCTAGCACAGAAATAAATTCAAGGCAAAATTCA
AACGATAAAGATTTTGAACGACGGACGACAAAAAAGTATTCGATATATAA
TGACAATGATTTCTTTCCAATCAAGGAGATATCGAAGTACGGGCAAATAA
TATTCTCCCTCTATTACGATTGGATTAGTAAGACTCTCGAAGTTACGGTA
AATCATGCAAAATATTTAATGGGATTTGGGACAAAACGCAAAAACCATTT
CTATGTCAAAGTTCTTTTAAAAACTAAAAGTTGTCCTCAATACACTAGCA
CCAATTCATTGTCTGGTGTGCCTGACAAAAATATCAATAAGTTCCAAAAA
AGTTTGAAAGGTTCTTTCAGAACTGCCATAAAATCTGATTTTTGCAATCC
TGTATTCAACGAAACCTTTAAATTTACCAACATTACTTCTTTACTGTTGA
AAGAATGTATTTTGCAAATGATAGTGAAAGAAGAAACACCAAAATTTCTG
GAGAAAAATATTGTTCTTGGTTGCGTTGATTTTGCTTTGGACGAGGCGCA
ACTGATTGACAAGCATGAATCTCTGAATGAGATTATCCGAGATATCAAGC
CAATTGGACAAATTGAGGATAAAGGCAAAGTTATCCTTTCCCTTCAATAC
AATCGACAGTTGACAGTACTGACGGTTAATGTAAAAGAGCTACTTCCTGG
CCCTGAACAGGTTTCCGATGTTTCAGTGGAATTATTTCTGCGCTCAATCG
ACTCTATCATGTATTCGAGGAAATTAGAATTAGACAGCAACCTAAAATCT
GGAAACAGCGAAAATTTTGATTTAGATAGTTGTTTAATAAATTCTGTTTG
CTTGGTGCTGGTGTTCTATGCCCGGATTCGGAACTGTTCCAGGACTCCAT
TGGGACGTCTGGTTGTCGGTCCTATACAATTTGCAAGTGGCGCTCGACTG
GCCCAATGGACCGAAATCAGTGCTGGAAATGAGGAGTCCGTAAAAATGCA
CGAAATCATTTAGATTTGTTTAATTTATCAACTGGTTCTTTGTTTATTTG
AATTAATTTAATGACGAATAAATATCTTTCACCTGGC

protein sequence of SMED30035718-orf-1

>SMED30035718-orf-1 ID=SMED30035718-orf-1|Name=SMED30035718-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=522bp
MINLIFYLLLFGIAGFCNCSPIQELQINNDNIIPLIIGISLMGFVIIILL
ASLCVCFIINKTSPDKKTADGKKAPPENIKLLDFVHKNSMELIEDKNEIN
KRTVENSEKSIHNLEKFPNKSIIEFSKIHRYRRASVPAVLSTLHEASPSL
EASSRKMSLSYNCVHEPQYDTKRNTIAHIDTDDTIMPESGPSTEINSRQN
SNDKDFERRTTKKYSIYNDNDFFPIKEISKYGQIIFSLYYDWISKTLEVT
VNHAKYLMGFGTKRKNHFYVKVLLKTKSCPQYTSTNSLSGVPDKNINKFQ
KSLKGSFRTAIKSDFCNPVFNETFKFTNITSLLLKECILQMIVKEETPKF
LEKNIVLGCVDFALDEAQLIDKHESLNEIIRDIKPIGQIEDKGKVILSLQ
YNRQLTVLTVNVKELLPGPEQVSDVSVELFLRSIDSIMYSRKLELDSNLK
SGNSENFDLDSCLINSVCLVLVFYARIRNCSRTPLGRLVVGPIQFASGAR
LAQWTEISAGNEESVKMHEII*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0000074	oocyte
PLANA:0000204	ovary
PLANA:0000231	vitelline gland
PLANA:0000429	neoblast
PLANA:0002089	reproductive organ
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR035892	C2_domain_sf
IPR030539	SYT15
IPR000008	C2_dom

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0005509	calcium ion binding
GO:0005544	calcium-dependent phospholipid binding
GO:0019905	syntaxin binding
GO:0030276	clathrin binding

Vocabulary: **cellular component**
Term	Definition
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0019898	extrinsic component of membrane
GO:0098793	presynapse

Vocabulary: **biological process**
Term	Definition
GO:0006906	vesicle fusion
GO:0017158	regulation of calcium ion-dependent exocytosis
GO:0048791	calcium ion-regulated exocytosis of neurotransmitter

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000008	C2 domain	SMART	SM00239	C2_3c	coord: 246..376 e-value: 2.3E-6 score: 37.1
IPR000008	C2 domain	PFAM	PF00168	C2	coord: 246..372 e-value: 0.0013 score: 19.0
IPR035892	C2 domain superfamily	GENE3D	G3DSA:2.60.40.150		coord: 225..381 e-value: 2.4E-15 score: 58.5
None	No IPR available	PANTHER	PTHR10024	SYNAPTOTAGMIN	coord: 308..516
None	No IPR available	SIGNALP_EUK	SignalP-TM	SignalP-TM	coord: 1..19 score: 0.824
None	No IPR available	SUPERFAMILY	SSF49562	C2 domain (Calcium/lipid-binding domain, CaLB)	coord: 222..366
None	No IPR available	TMHMM	TMhelix		coord: 37..59
None	No IPR available	TMHMM	TMhelix		coord: 5..27
IPR030539	Synaptotagmin-15	PANTHER	PTHR10024:SF234	SYNAPTOTAGMIN-15	coord: 308..516

Main menu

Synaptotagmin XV-like protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 26

Owlery

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