Granulin b
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035642 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 20
Homology
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]) HSP 1 Score: 265.003 bits (676), Expect = 1.961e-80 Identity = 165/449 (36.75%), Postives = 223/449 (49.67%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI-------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV-------ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 V DGS+ CCP A CC D+ HCCP C+L C + + K+PA SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA ++ V C + C DG TCC + G++ CCP++ AVCC D HCCP C+ GTC+ +V K L +P L + P D S+C + TCC L+ G +GCCP AVCCSD CCPQ C ++ G C ++ S ++ + P R I C GQTCC G S+ CC A CC D+ HCCP CN+ +C+ + A + SP + V+ ++C G C TCC ++CCPY VCC+D HCCP C+ C + ++ Sbjct: 141 VMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRC--ITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 580 HSP 2 Score: 263.848 bits (673), Expect = 5.108e-80 Identity = 164/445 (36.85%), Postives = 229/445 (51.46%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFP 1535 T G+ SCCP+ AV C D HCCP+ C+ + +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L C L + + + + SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA + ++C D +C G TCC L G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P + R + C TCC+L +G+ +GCCP A CCSD HCCPQ C + +G C +E + ++ P S+ P C Q TCCPS S++CC P+AVCC D HCCP +C++ +SC+K ++ P Sbjct: 75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQP 504 HSP 3 Score: 234.187 bits (596), Expect = 8.258e-69 Identity = 144/377 (38.20%), Postives = 193/377 (51.19%), Query Frame = 3 Query: 408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L C + K++ + + A+S+ S+ CPD S C G+TCC L G YGCCP NA CCSD L CCPQ+TVC+L C SK + L+ + V V C + C DG TCC+L +G ++GCCP++ A CC D IHCCP C+ KGTC+ HQ +E + + L + C N S C TCC + + CCP P AVCCSDH HCCP +C Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 410
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]) HSP 1 Score: 231.876 bits (590), Expect = 1.278e-69 Identity = 142/392 (36.22%), Postives = 195/392 (49.74%), Query Frame = 3 Query: 408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL------KEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L C + K++ + + A+S+ S+ CPD S C G+TCC L G YGCCP NA CCSD L CCPQ+TVC+L C SK + L+ + V V C + C DG TCC+L +G ++GCCP++ A CC D IHCCP C+ KGTC+ HQ +E + + L + C N S C TCC ++CCPY VCC+D HCCP C+ C + ++ Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 425 HSP 2 Score: 209.149 bits (531), Expect = 4.975e-61 Identity = 129/357 (36.13%), Postives = 177/357 (49.58%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC 1292 T G+ SCCP+ AV C D HCCP+ C+ + +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L C L + + + + SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA + ++C D +C G TCC L G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P + R + C TCC+ + CCPY CC+D+ HCCP C C Sbjct: 75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCR-DNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKC 417 HSP 3 Score: 186.422 bits (472), Expect = 1.676e-52 Identity = 112/297 (37.71%), Postives = 151/297 (50.84%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI-------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC--------DSKTKKPSL 1088 V DGS+ CCP A CC D+ HCCP C+L C + + K+PA SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA ++ V C + C DG TCC + G++ CCP++ AVCC D HCCP C+ GTC+ +V K L +P L + P D S+C + TCC + + CCP+ VCC+D+ CCP C C D+ + P+L Sbjct: 141 VMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRC--ITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPAL 434
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]) HSP 1 Score: 214.157 bits (544), Expect = 2.161e-63 Identity = 133/349 (38.11%), Postives = 181/349 (51.86%), Query Frame = 3 Query: 438 SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPY 1430 SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA ++ V C + C DG TCC + G++ CCP++ AVCC D HCCP C+ GTC+ +V K L +P L + P D S+C + TCC L+ G +GCCP AVCCSD CCPQ C ++ G C ++ S ++ + P R + C GQTCC G S+ CC A CC D+ HCCP CN+ +C+ + A + SP + V+ ++C G C TCC ++CCPY Sbjct: 19 SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY 360 HSP 2 Score: 198.364 bits (503), Expect = 2.115e-57 Identity = 120/308 (38.96%), Postives = 165/308 (53.57%), Query Frame = 3 Query: 666 SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA + ++C D +C G TCC L G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P + R + C TCC+L +G+ +GCCP A CCSD HCCPQ C + +G C +E + ++ P S+ P C Q TCCPS S++CC P+AVCC D HCCP +C++ +SC+K ++ P Sbjct: 19 SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFL 322 HSP 3 Score: 192.2 bits (487), Expect = 4.495e-55 Identity = 119/325 (36.62%), Postives = 169/325 (52.00%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD--SKLKEVVTKMKLKIPAISN-LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPY 1214 G Y CCP +A CCSD HCCPQ+T C+L + C S + T + K+PA ++ V C + C DG TCC + G++ CCP++ AVCC D HCCP C+ GTC+ +++ + L P + V C + S C TCC + G + CCP AVCCSD +HCCPQ C + G C S++ + KM + ++S+ I C D ++C G TCC GS+ CC +AVCC D+ CCP CN+ A +C+ + + +P+ + V V C G + C D QTCC+ + CCPY Sbjct: 41 GKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGC-DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVEC-GEGHFCHDNQTCCR-DNRQGWACCPY 360 HSP 4 Score: 162.925 bits (411), Expect = 3.337e-44 Identity = 95/225 (42.22%), Postives = 124/225 (55.11%), Query Frame = 3 Query: 843 KEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 K++ + + A+S+ S+ CPD S C G+TCC L G YGCCP NA CCSD L CCPQ+TVC+L C SK + L+ + V V C + C DG TCC+L +G ++GCCP++ A CC D IHCCP C+ KGTC+ HQ +E + + L + C N S C TCC + + CCP P AVCCSDH HCCP +C Sbjct: 3 KKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 224 HSP 5 Score: 106.301 bits (264), Expect = 3.487e-24 Identity = 65/169 (38.46%), Postives = 86/169 (50.89%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPY 752 T G + CCP AVCCSD QHCCPQ C + +G C + V K+ +S+ + C + C G TCC GGS+ACC AVCC D++HCCP CN+ A +C+ KEVV+ + P + V C + C+D TCC +ACCPY Sbjct: 196 TSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCE---KEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY 360
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]) HSP 1 Score: 201.445 bits (511), Expect = 4.125e-58 Identity = 130/393 (33.08%), Postives = 182/393 (46.31%), Query Frame = 3 Query: 408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + +S+ ++ CPD Q +C D STCC + GS+ CCP AVCC D HCCP C+ GTC+ +V K L +P L + P D S+C + TCC L+ G +GCCP AVCCSD CCPQ C ++ G C ++ S ++ + P R + C GQTCC G S+ CC A CC D+ HCCP CN+ +C+ + A + SP + V+ ++C G C TCC ++CCPY VCC+D HCCP C+ C + ++ Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 423 HSP 2 Score: 195.282 bits (495), Expect = 9.273e-56 Identity = 124/356 (34.83%), Postives = 175/356 (49.16%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD--SKLKEVVTKMKLKIPAISN-LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC 1292 T G+ SCCP+ AV C D HCCP+ C+ + +C + +S+ ++ CPD Q +C D STCC + GS+ CCP AVCC D HCCP C+ GTC+ +++ + L P + V C + S C TCC + G + CCP AVCCSD +HCCPQ C + G C S++ + KM + ++S+ I C D ++C G TCC GS+ CC +AVCC D+ CCP CN+ A +C+ + + +P+ + V V C G + C D QTCC+ + CCPY CC+D+ HCCP C C Sbjct: 75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGC-DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVEC-GEGHFCHDNQTCCR-DNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKC 415 HSP 3 Score: 167.933 bits (424), Expect = 1.046e-45 Identity = 106/299 (35.45%), Postives = 145/299 (48.49%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPA-----SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK----MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC--------DSKTKKPSL 1088 V DGS+ CCP AVCC D HCCP C+ KGTC+ +++ + L P + V C + S C TCC + G + CCP AVCCSD +HCCPQ C + G C + E+V ++ K+PA S + C + C G TCC GGS+ACC AVCC D++HCCP CN+ A +C+ KEVV+ + P + +EC +G C TCC + + CCP+ VCC+D+ CCP C C D+ + P+L Sbjct: 141 VMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC-QRGSEIVAGLE-KMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCE---KEVVSAQPATFLARSPHVGVKDVECGEG-HFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPAL 432 HSP 4 Score: 167.548 bits (423), Expect = 1.537e-45 Identity = 105/313 (33.55%), Postives = 149/313 (47.60%), Query Frame = 3 Query: 636 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFP 1535 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + S +I+CPD C +TCC++ DGS+GCCP AVCC D + CCP C+ GTC+ + + K P + R + C TCC+L +G+ +GCCP A CCSD HCCPQ C + +G C +E + ++ P S+ P C Q TCCPS S++CC P+AVCC D HCCP +C++ +SC+K ++ P Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNN-----------SVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQP 347
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601]) HSP 1 Score: 75.485 bits (184), Expect = 4.012e-15 Identity = 47/151 (31.13%), Postives = 66/151 (43.71%), Query Frame = 3 Query: 636 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSS--------------AVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNL 1046 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + S +I+CPD C +TCC++ DGS+GCCP A CC D++ CCP C+L Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGNN-----------SVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187 HSP 2 Score: 74.7146 bits (182), Expect = 8.545e-15 Identity = 48/151 (31.79%), Postives = 67/151 (44.37%), Query Frame = 3 Query: 408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSS--------------AVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNL 815 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187 HSP 3 Score: 68.9366 bits (167), Expect = 6.998e-13 Identity = 41/134 (30.60%), Postives = 61/134 (45.52%), Query Frame = 3 Query: 918 STCKTGATCCLLSDGSYGCCPFS--------------NAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNI 1277 + C G +C G+ CCPF AV C D CCP+ C+ +C ++ N V + CP ++++C D TCC + G S+GCCP A+CC D++HCCP C++ Sbjct: 65 AHCSAGHSCIFTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGN----------NSVGAIQCPDSQFECPDFSTCCVMVDG-SWGCCPMPQASCCEDRVHCCPHGAFCDL 187 HSP 4 Score: 68.9366 bits (167), Expect = 7.133e-13 Identity = 42/124 (33.87%), Postives = 58/124 (46.77%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSS--------------AVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNL 587 T G+ SCCP+ AV C D HCCP+ C+ + +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L Sbjct: 75 FTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187 HSP 5 Score: 55.0694 bits (131), Expect = 3.644e-8 Identity = 41/130 (31.54%), Postives = 56/130 (43.08%), Query Frame = 3 Query: 1149 QCSDGQTCCKLPAGDSYGCCPYSA--------------ATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSL 1493 CS G +C +G S CCP+ A C D HCCP+ C+ + +C ++ V +I+CP+ C TCC + S+ CCP P A CC D HCCP+ C L Sbjct: 66 HCSAGHSCIFTVSGTS-SCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGNNS-------VGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187
BLAST of Granulin b vs. Ensembl Celegans
Match: pgrn-1 (ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:Q7JKP2]) HSP 1 Score: 110.538 bits (275), Expect = 2.853e-26 Identity = 83/268 (30.97%), Postives = 119/268 (44.40%), Query Frame = 3 Query: 633 MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVC-------------NLSAGTCDSKTKKPSLLI---------------KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSY---GCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKI 1325 + L V + + C +++C+D TCC + ++ CCP +AVCC D+ HCCP T C+ C ++ V MK K PA + + CPD +S C G+TCCLL GSYGCCP NAVCC+D L CCP C +L S +KP++ + V+ + C G C TCC + + CCP S A CC + CCP C ++ G C+ A+ + + Sbjct: 84 LFLAVFLCRVTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVP-MKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIAC-GVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICCENT--CCPAGYHC-VDGGKCEKHAKTMRTRF 346 HSP 2 Score: 109.768 bits (273), Expect = 4.507e-26 Identity = 88/263 (33.46%), Postives = 121/263 (46.01%), Query Frame = 3 Query: 405 IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSIL------SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDA----GTCDSKLKEVVTKMKLKIPAISNLS-----------------------IECPDGSSTCKTGATCCLLSDGSYG-----CCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTK 1076 + L V + + C +++C+D TCC + ++ CCP +AVCC D+ HCCP T C+ C ++ V MK K PA + VVCPD+ S+C DGSTCC + GSY CCP +AVCC+D HCCP C+ L++ + + PA+ LS I C G TC TCC + G G CCP SNA+CC + +CCP C + G C+ K Sbjct: 84 LFLAVFLCRVTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVP-MKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVG-KTCPAKTTCCNVR-GKNGEPKTMCCPLSNAICCEN--TCCPAGYHC-VDGGKCEKHAK 340 HSP 3 Score: 108.997 bits (271), Expect = 1.032e-25 Identity = 84/246 (34.15%), Postives = 107/246 (43.50%), Query Frame = 3 Query: 909 DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS--------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCN-------------INK--GTCDHQAEALEIKISPIL----------------VESIKCPNGSLCGQKGTCC----PSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 D + C TCC L D ++GCCP NAVCC D+ CCP T C+ C K KKP+ KT + N N V+CP +C DG TCC L G SYGCCP A CC+D +HCCP C+ + K T H+ A+E V+ I C G C K TCC + CCP NA+CC + CCP C ++ C+K+ Sbjct: 99 DAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPAR--KTVERNQFNEVVCPDKASKCPDGSTCCLLEQG-SYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICCEN--TCCPAGYHC-VDGGKCEKH 338 HSP 4 Score: 101.293 bits (251), Expect = 3.833e-23 Identity = 77/235 (32.77%), Postives = 104/235 (44.26%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLK-----VPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCP-----QNTVCNLDAGTCDSKLKEVVTKMKLK----------------------VPASSILSVVCPDQSQCNDGSTCCAVAGGS----YACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKM 863 D ++ CCP +AVCC D+ HCCP T C+ C ++ V K K V + VVCPD+ S+C DGSTCC + GSY CCP +AVCC+D HCCP C+ + K T + K P S + + C C +TCC V G + CCP S+A+CC + CCP C +D G C+ K + T+ Sbjct: 115 DNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICCENT--CCPAGYHC-VDGGKCEKHAKTMRTRF 346 HSP 5 Score: 85.8853 bits (211), Expect = 5.835e-18 Identity = 57/152 (37.50%), Postives = 77/152 (50.66%), Query Frame = 3 Query: 1140 AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIK------ISPILVESIKCPN-GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFH 1550 A+ +CSD +TCCKL +++GCCP A CC D+ HCCP T C+ C D + ++ K + + CP+ S C TCC SY CCP PNAVCC+D HCCPN +C + + C +N L KF + H Sbjct: 100 AETECSDDETCCKL-GDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC--HGQFCSQNFAMIPHLRKFASTSIH 248 HSP 6 Score: 51.2174 bits (121), Expect = 1.128e-6 Identity = 24/57 (42.11%), Postives = 32/57 (56.14%), Query Frame = 3 Query: 1338 VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508 V + +C + C TCC ++++ CCP PNAVCC D SHCCP T+C C Sbjct: 93 VTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARC 149
BLAST of Granulin b vs. Ensembl Celegans
Match: pgrn-1 (ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:Q7JKP2]) HSP 1 Score: 105.916 bits (263), Expect = 8.753e-25 Identity = 56/129 (43.41%), Postives = 72/129 (55.81%), Query Frame = 3 Query: 675 CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCN 1043 C +++C+D TCC + ++ CCP +AVCC D+ HCCP T C+ C E MK K PA + + CPD +S C G+TCCLL GSYGCCP NAVCC+D L CCP C+ Sbjct: 98 CDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGA-DEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCH 225 HSP 2 Score: 103.219 bits (256), Expect = 6.652e-24 Identity = 57/130 (43.85%), Postives = 69/130 (53.08%), Query Frame = 3 Query: 909 DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS--------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCN 1274 D + C TCC L D ++GCCP NAVCC D+ CCP T C+ C K KKP+ KT + N N V+CP +C DG TCC L G SYGCCP A CC+D +HCCP C+ Sbjct: 99 DAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPAR--KTVERNQFNEVVCPDKASKCPDGSTCCLLEQG-SYGCCPVPNAVCCADMLHCCPNGFTCH 225 HSP 3 Score: 102.449 bits (254), Expect = 1.326e-23 Identity = 56/129 (43.41%), Postives = 73/129 (56.59%), Query Frame = 3 Query: 447 CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSIL------SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCN 812 C +++C+D TCC + ++ CCP +AVCC D+ HCCP T C+ C E MK K PA + VVCPD+ S+C DGSTCC + GSY CCP +AVCC+D HCCP C+ Sbjct: 98 CDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGA-DEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCH 225 HSP 4 Score: 88.9669 bits (219), Expect = 4.329e-19 Identity = 50/112 (44.64%), Postives = 63/112 (56.25%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSIL------SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCN 584 D ++ CCP +AVCC D+ HCCP T C+ C E +K K PA + VVCPD+ S+C DGSTCC + GSY CCP +AVCC+D HCCP C+ Sbjct: 115 DNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGA-DEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCH 225 HSP 5 Score: 86.6557 bits (213), Expect = 3.024e-18 Identity = 57/152 (37.50%), Postives = 77/152 (50.66%), Query Frame = 3 Query: 1140 AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIK------ISPILVESIKCPN-GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFH 1550 A+ +CSD +TCCKL +++GCCP A CC D+ HCCP T C+ C D + ++ K + + CP+ S C TCC SY CCP PNAVCC+D HCCPN +C + + C +N L KF + H Sbjct: 100 AETECSDDETCCKL-GDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC--HGQFCSQNFAMIPHLRKFASTSIH 248 HSP 6 Score: 51.2174 bits (121), Expect = 1.043e-6 Identity = 23/50 (46.00%), Postives = 31/50 (62.00%), Query Frame = 3 Query: 1338 VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 V + +C + C TCC ++++ CCP PNAVCC D SHCCP T+C Sbjct: 93 VTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTC 142
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grnb (granulin b [Source:ZFIN;Acc:ZDB-GENE-030131-7393]) HSP 1 Score: 280.796 bits (717), Expect = 2.026e-85 Identity = 179/473 (37.84%), Postives = 252/473 (53.28%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--------------DSKLKEVVTKMKLKVPAS--SILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-----IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD-------SKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 +T G Y CCP A CCSD HCC Q T C+L C + + + V K++ K+ A VVCPD +S+C D +TCC + G + CCP +AVCC D++HCCPQ T C+L C D++ ++ + K + +PA +I V+CPD+ S+C + +TCC + GSY CCP AVCCSD++HCCP+ T C+L TC S V++M KIPA++ L + C + + C +G TCC +GS+ CCP AVCC D + CCP+ T+CN++A +CD S + K P P + C TCCKL +GD +GCCP A CC D +HCCP +VCN+ TC+ +++ ++IS +V+ I C S C TCC + S++CCP P AVCC+D HCCP +C L SC ++ L P Sbjct: 36 LTPSGGYGCCPLPHAECCSDHLHCCYQGTLCDLEHSKCVNKTHVLDWVEKVEAKLQA-----VVCPDGESECPDDTTCCQMPDGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYGSSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLS--ANGVSEMATKIPAVTVLKPKEEVVPC-NETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPAGLSVSVPWMEKVSTKPIAPPPNKKC---DESSSCPGESTCCKLSSGD-WGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDS-GLRISVPMVKKIPAVSVPSQKQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAWFRKEP 495 HSP 2 Score: 271.937 bits (694), Expect = 5.207e-82 Identity = 173/463 (37.37%), Postives = 245/463 (52.92%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--------------DSVLKEVVTKIKLKVPAS--SILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS---IECP-----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA--EALEIKISPILVESIKCPNGSLCGQKGTCCPSAN--------DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI 1520 DG + CCP +AVCC D++HCCPQ T C+L C D+ ++ + K + +PA +I V+CPD+ S+C + +TCC + GSY CCP AVCCSD++HCCP+ T C+L TC S V++M K+PA ++L V C + C+ G+TCC GS+ACCP AVCC D HCCP+ T+CN+ A +CD + + +P + +S I P D SS+C +TCC LS G +GCCP AVCC D + CCP +VCN++A TC++ + L I + V P K C + G TCCKL +G S+ CCP A CC+D+ HCCPQ C++ + +C + P L E+ + + +C + T CP + + CCP P AVCC D HCCP+ +C+ SC K + Sbjct: 113 DGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYGSSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLS--ANGVSEMATKIPAVTVLKPKEEVVPCNETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDP-----AGLSVSVPWMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDS-GLRISVPMVKKIPAVSVPSQKQNCDETSSCPTGTTCCKLTSG-SWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAWFRKEPALRETQRVEDRHMCDAQ-TSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSCTKGL 565 HSP 3 Score: 265.003 bits (676), Expect = 2.069e-79 Identity = 173/445 (38.88%), Postives = 233/445 (52.36%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK----VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----DSKLKEVVTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQP------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV--------ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514 GSY CCP AVCCSD++HCCP+ T C+L TC S V+++ K+PA ++L V C + C+ G+TCC GS+ACCP AVCC D HCCP+ T+CN+ A +CD V+ ++ P + + C + S C STCC ++ G + CCP AVCC D HCCP +VCN+ A TC DS L+ V +K KIPA+S S + D +S+C TG TCC L+ GS+ CCP AVCC+D+ CCPQ C+L+ +C ++ PS+ +P +R +C A+ C TCC + +GCCP A CC D HCCP CN K +C HQ K + + E +KC + + C TCC + CCP AVCC DH HCCP C L +C+K Sbjct: 207 GSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLSA--NGVSEMATKIPAVTVLKPKEEVVPCNETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPAGLSVSVPWMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVPMVK-KIPAVSVPSQKQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSC-VRSGLPSMAWFRKEPALRETQRVEDRHMC-DAQTSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSCTKGLHQIPWFTKKTARVWKSSDELLGHEDVKCDSSTSCPSGSTCCILPTGQWGCCPLVKAVCCEDHEHCCPQGYICKLELGTCEK 646 HSP 4 Score: 258.07 bits (658), Expect = 8.332e-77 Identity = 158/413 (38.26%), Postives = 219/413 (53.03%), Query Frame = 3 Query: 438 SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--------------DSKLKEVVTKMKLKIPAISN--LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-------DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI-----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC----DKNILLKFPIINFHP 1553 +++CPD C DG+TCC G Y CCP A CCSD HCC Q T+C+L+ C +K + + V K++ K+ A VVCPD +S+C D +TCC + G + CCP +AVCC D++HCCPQ T C+L C D++ ++ + K + +PA N + CPD S C TCCLL GSYGCCP AVCCSD+ CCP+ T C+L TC + TK P++ + P V+ CS G TCCK P G S+ CCP A CC D IHCCP+ T+CN+ +CD A + +S +E + KC S C + TCC ++ + CCP P AVCC DH HCCP+ + C++ ++C D + + P++ P Sbjct: 19 ALICPDGGMCEDGNTCCLTPSGGYGCCPLPHAECCSDHLHCCYQGTLCDLEHSKCVNKTHVLDWVEKVEAKLQA-----VVCPDGESECPDDTTCCQMPDGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYGSSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLSANGVSEMATKIPAVTVL----KPKEEVVPCNETVACSSGTTCCKTPEG-SWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPA---GLSVSVPWMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVPMVKKIP 418 HSP 5 Score: 254.988 bits (650), Expect = 1.217e-75 Identity = 160/439 (36.45%), Postives = 223/439 (50.80%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD-----SVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----DSKLKEVVTKMKLKVPASSILSVV--CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---DGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-------TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514 T +GS++CCP AVCC D HCCP+ T CN+ +CD SV + K+ K P + + C + S C STCC ++ G + CCP AVCC D HCCP +VCN+ A TC DS L+ V +K K+PA S+ S C + S C G+TCC + GS+ACCP AVCC+D+ HCCPQ C+L +C + + + +E D ++C TCC ++ G +GCCP AVCC D CCP CN +C TKK + + K+ + + + C G TCC LP G +GCCP A CC D HCCPQ +C + GTC+ + + + ++ + + I+C + C +CC A+ +++CCPY AVCC D HCCP C + C K Sbjct: 283 TPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPAGLSVSVPWMEKVSTK-PIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVPMVK-KIPAVSVPSQKQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAWFRKEPALRETQRVEDRHMCDAQTSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSCTKGLHQIPWFTKKTARVWKSSDELLGHEDVKCDSSTSCPSGSTCCILPTG-QWGCCPLVKAVCCEDHEHCCPQGYICKLELGTCEKASADVSVSLTAVQMPEIQCDTFTRCAHTQSCCRLADSTWACCPYTQAVCCKDMKHCCPMGYKCDPKVQGCTK 718
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 265.388 bits (677), Expect = 1.615e-78 Identity = 177/476 (37.18%), Postives = 243/476 (51.05%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEV----VTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 T DG ++CCP AVCC D HCCP +C++ G+C+ S +++V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ + +S +S I C D + C G+TCC DG +GCCP AVCC D + CCP CN++AG+CD + +K + ++ Q P +V C A + C + TCCK AG+ +GCCP+S A CC+D HCCP + CN++ +C + A E +P L + +KC S C TCC + D CCP+P AVCC D HCCP C L +SC K L I Sbjct: 306 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACND-TVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQ-RPSGKVKC-NATHGCPESSTCCKNIAGE-WGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQL 777 HSP 2 Score: 241.891 bits (616), Expect = 6.192e-70 Identity = 168/511 (32.88%), Postives = 240/511 (46.97%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS--------------VLKEVVTKIKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLKIPAISNL------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT--------------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVESIKCPNGSL-------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544 DG + CCP AVCC DK HCCP++T C++ C S L+ K K P + + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ N+ + C D ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C+ + +K + + T +PV+ I C DG TCCK G+ +GCCP A CC D IHCCP CN+ G+CD + ++ ++ P+ + + + P+G + C + TCC + + CCP+ AVCC+D HCCP + C+L++ SC K ++ P N Sbjct: 189 DGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTV--SPVSSDIACNDTVACPDGSTCCKDKDGE-WGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVV-IPWYN 694 HSP 3 Score: 234.187 bits (596), Expect = 4.410e-67 Identity = 165/483 (34.16%), Postives = 232/483 (48.03%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC---DSKTKKPSLLIKTFQPNP---VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISP------------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFVFT 1583 T +G ++CCP AVCC D HCCP+ +CN+ C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ V S +S + C D C DGSTCC G + CCP AVCC D HCCP CN+ AG+CD V V K+ + + A S ++C + + C +TCC G +GCCPFS AVCC+D CCP + CNLS+ +C D + + P P + V C + CS TCC L + D GCCP+ A CC D+ HCCP+ C++ + +C + L ++I+ ++V+ ++C G C TCC ++ ++ CCP P AVCC D HCCP C L +N+ F+ T Sbjct: 394 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKC-NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKC-DEQSSCSADSTCCLL-SKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSC-VKTTRLYVEITQLTHIRSNKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPGGTCISAGDLDWSNWVNWKLFFSKKKRALT 872 HSP 4 Score: 226.483 bits (576), Expect = 2.578e-64 Identity = 157/495 (31.72%), Postives = 221/495 (44.65%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGA------------KYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE------------SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 SY CCP + + CSD +HCCP + EC+ + C +K KV + +V+C + S+C +TCC G + CCP AVCC DK HCCP++TVC++ A C S +L+ K K P + + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ + +S++S + P + ++ C G TCC +G + CCP AVCC D + CCP+ CN++A C+ L+K PV P C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + ++ ++ + PI + I C + C TCC + + CCP P AVCC D HCCP+ C++ SCD Sbjct: 127 SYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC----------VKRKV---KVQTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQ---TPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 604 HSP 5 Score: 206.068 bits (523), Expect = 5.913e-57 Identity = 152/495 (30.71%), Postives = 215/495 (43.43%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-----LKEVVTKIKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKIPAISNLS-----------------------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPN-------------GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 G +SCCP+ CC D HCCP+ C++ TC + L + K +P S + P C DGS+C C + SY CCP + + CSD +HCCP + C+ D+ C K K+KV +V+C + S+C +TCC G + CCP AVCC DK HCCP++TVC++ A C S +L+ K K P + + C D ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C+ + S + + Q + V+ + C+DG TCCK GD + CCP A CC D +HCCP+ CNI C+ E + V+S PN + C TCC + + ++CCP P AVCC D HCCP+ C + SC+ Sbjct: 37 GGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGD-WACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCE 516 HSP 6 Score: 196.052 bits (497), Expect = 1.657e-53 Identity = 135/458 (29.48%), Postives = 204/458 (44.54%), Query Frame = 3 Query: 405 IKLKVPASSILSVVC---PDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----LKEVVTKMKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-----------------------DSKTKKPSLLIKTFQP-------NPVNRVICPGAKYQ-------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 ++L V + + V+C P+ C G +CC G ++CCP+ CC D HCCP+ +C++ TC + L + K +P S + P C DGS+C C + SY CCP + + CSD +HCCP + C+ D+ C K K+K+ ++ C +G+S C TCC DG +GCCP AVCC DK+ CCP++TVC++ A C D K K+P T +P N++ A++Q C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + ++ ++ + PI + + C + + C TCC + ++CCP P AVCC D HCCP C++ C+ + + P++ P Sbjct: 2 LRLTVCLAVVTLVICSQCPNNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 445
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 265.388 bits (677), Expect = 1.807e-78 Identity = 174/475 (36.63%), Postives = 242/475 (50.95%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEV----VTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 T DG ++CCP AVCC D HCCP +C++ G+C+ S +++V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ + S+ S + P + ++ C G+TCC DG + CCP AVCC D + CCP CN++AG+CD + +K + ++ Q P +V C A + C + TCCK AG+ +GCCP+S A CC+D HCCP + CN++ +C + A E +P L + +KC S C TCC + D CCP+P AVCC D HCCP C L +SC K L I Sbjct: 306 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQ-RPSGKVKC-NATHGCPESSTCCKNIAGE-WGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQL 777 HSP 2 Score: 237.269 bits (604), Expect = 3.477e-68 Identity = 165/486 (33.95%), Postives = 232/486 (47.74%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICP---------GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISP------------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFVFT 1583 T +G ++CCP AVCC D HCCP+ +CN+ C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ V +S S V C D + C DGSTCC G +ACCP AVCC D HCCP CN+ AG+CD V V K+ + + A S ++C + + C +TCC G +GCCPFS AVCC+D CCP + CNLS+ +C K ++I + P + CS TCC L + D GCCP+ A CC D+ HCCP+ C++ + +C + L ++I+ ++V+ ++C G C TCC ++ ++ CCP P AVCC D HCCP C L +N+ F+ T Sbjct: 394 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKC-NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSC----IKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLL-SKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSC-VKTTRLYVEITQLTHIRSNKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPGGTCISAGDLDWSNWVNWKLFFSKKKRALT 872 HSP 3 Score: 237.269 bits (604), Expect = 4.002e-68 Identity = 166/509 (32.61%), Postives = 235/509 (46.17%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS--------------VLKEVVTKIKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLKIPAISNL------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-FQPNPVNRVICPGAK-----------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVESIKCPNGSL-------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544 DG + CCP AVCC DK HCCP++T C++ C S L+ K K P + + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ N+ + C D ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C+ + + K +P +V A C DG TCCK G + CCP A CC D IHCCP CN+ G+CD + ++ ++ P+ + + + P+G + C + TCC + + CCP+ AVCC+D HCCP + C+L++ SC K ++ P N Sbjct: 189 DGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVV-IPWYN 694 HSP 4 Score: 227.639 bits (579), Expect = 1.040e-64 Identity = 156/495 (31.52%), Postives = 224/495 (45.25%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGA------------KYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 SY CCP + + CSD +HCCP + EC+ + C +K KV + +V+C + S+C +TCC G + CCP AVCC DK HCCP++TVC++ A C S +L+ K K P + + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ + +S++S + P + ++ C G TCC +G + CCP AVCC D + CCP+ CN++A C+ L+K PV P C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + ++ ++ + PI + + C + + C TCC + + ++CCP P AVCC D HCCP+ C++ SCD Sbjct: 127 SYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC----------VKRKV---KVQTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQ---TPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 604 HSP 5 Score: 205.682 bits (522), Expect = 6.030e-57 Identity = 152/495 (30.71%), Postives = 215/495 (43.43%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-----LKEVVTKIKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKIPAISNLS-----------------------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPN-------------GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 G +SCCP+ CC D HCCP+ C++ TC + L + K +P S + P C DGS+C C + SY CCP + + CSD +HCCP + C+ D+ C K K+KV +V+C + S+C +TCC G + CCP AVCC DK HCCP++TVC++ A C S +L+ K K P + + C D ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C+ + S + + Q + V+ + C+DG TCCK GD + CCP A CC D +HCCP+ CNI C+ E + V+S PN + C TCC + + ++CCP P AVCC D HCCP+ C + SC+ Sbjct: 37 GGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGD-WACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCE 516 HSP 6 Score: 196.052 bits (497), Expect = 1.657e-53 Identity = 135/458 (29.48%), Postives = 204/458 (44.54%), Query Frame = 3 Query: 405 IKLKVPASSILSVVC---PDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----LKEVVTKMKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-----------------------DSKTKKPSLLIKTFQP-------NPVNRVICPGAKYQ-------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 ++L V + + V+C P+ C G +CC G ++CCP+ CC D HCCP+ +C++ TC + L + K +P S + P C DGS+C C + SY CCP + + CSD +HCCP + C+ D+ C K K+K+ ++ C +G+S C TCC DG +GCCP AVCC DK+ CCP++TVC++ A C D K K+P T +P N++ A++Q C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + ++ ++ + PI + + C + + C TCC + ++CCP P AVCC D HCCP C++ C+ + + P++ P Sbjct: 2 LRLTVCLAVVTLVICSQCPNNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 445
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 266.544 bits (680), Expect = 5.462e-78 Identity = 179/485 (36.91%), Postives = 235/485 (48.45%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-------VLKEVVTKIKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS------------------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 T DG ++CCP AVCC D HCCP +C++ G+C+ V K V I+ + A + +S + C D C DGSTCC G + CCP AVCC D HCCP CN+ AG+CD V + K K+ V +S S V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V K+ + I N ++ CPDGS TCC DG +GCCP AVCC D + CCP CN++AG+CD + +K + ++ Q P +V C A + C + TCCK AG+ +GCCP+S A CC+D HCCP + CN++ +C + A E +P L + +KC S C TCC + D CCP+P AVCC D HCCP C L +SC K L I Sbjct: 479 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGS-------TCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQ-RPSGKVKC-NATHGCPESSTCCKNIAGE-WGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQL 953 HSP 2 Score: 259.996 bits (663), Expect = 1.530e-75 Identity = 169/479 (35.28%), Postives = 240/479 (50.10%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQP-----------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVESIKCPNGSL-------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544 T +G ++CCP AVCC D HCCP+ +CN+ C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ V S +S + C D C DGSTCC G + CCP AVCC D HCCP CN+ AG+CD V + K K+ + S+ S + P + ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C DS P + +P +PV+ + C DG TCCK GD +GCCP A CC D IHCCP CN+ G+CD + ++ ++ P+ + + + P+G + C + TCC + + CCP+ AVCC+D HCCP + C+L++ SC K ++ P N Sbjct: 394 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGSTCCKDKDGD-WGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVV-IPWYN 870 HSP 3 Score: 251.521 bits (641), Expect = 1.399e-72 Identity = 170/483 (35.20%), Postives = 235/483 (48.65%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEV----VTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-FQPNPVNRVICPGAK-----------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD-----------------HQAEALEIKISPILV-----ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 T DG ++CCP AVCC D HCCP +C++ G+C+ S +++V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ + +S +S I C D + C G+TCC DG +GCCP AVCC D + CCP CN++AG+CD + + K +P +V A C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + + K+SP+ +++ CP+GS TCC + + CCP P AVCC D HCCP+ C++ SCD Sbjct: 306 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACND-TVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGS------TCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 780 HSP 4 Score: 238.424 bits (607), Expect = 7.320e-68 Identity = 165/510 (32.35%), Postives = 233/510 (45.69%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS--------------VLKEVVTKIKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLKIPAISNL------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT--------------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 DG + CCP AVCC DK HCCP++T C++ C S L+ K K P + + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ N+ + C D ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C+ + +K + + T +PV+ I C DG TCCK G+ +GCCP A CC D IHCCP CN+ G+CD + ++ ++ + PI + + C + + C TCC + + ++CCP P AVCC D HCCP+ C + SC+ + Sbjct: 189 DGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTV--SPVSSDIACNDTVACPDGSTCCKDKDGE-WGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDS 694 HSP 5 Score: 237.269 bits (604), Expect = 1.718e-67 Identity = 171/486 (35.19%), Postives = 229/486 (47.12%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS----------VLKEVVTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKV--------------PASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC---DSKTKKPSLLIKTFQPNP---VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISP------------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFVFT 1583 DG + CCP AVCC D HCCP +CN+ G+CD V + K K+ V +S S V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V K+ V P SS V C D C DGSTCC G + CCP AVCC D HCCP CN+ AG+CD V V K+ + + A S ++C + + C +TCC G +GCCPFS AVCC+D CCP + CNLS+ +C D + + P P + V C + CS TCC L + D GCCP+ A CC D+ HCCP+ C++ + +C + L ++I+ ++V+ ++C G C TCC ++ ++ CCP P AVCC D HCCP C L +N+ F+ T Sbjct: 569 DGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSS--DVACNDTVACPDGSTCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKC-NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKC-DEQSSCSADSTCCLL-SKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSC-VKTTRLYVEITQLTHIRSNKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPGGTCISAGDLDWSNWVNWKLFFSKKKRALT 1048 HSP 6 Score: 226.483 bits (576), Expect = 1.185e-63 Identity = 157/495 (31.72%), Postives = 221/495 (44.65%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGA------------KYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE------------SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 SY CCP + + CSD +HCCP + EC+ + C +K KV + +V+C + S+C +TCC G + CCP AVCC DK HCCP++TVC++ A C S +L+ K K P + + V C D + C DGSTCC G +ACCP AVCC D HCCP C++ AG+C+ V + K K+ + +S++S + P + ++ C G TCC +G + CCP AVCC D + CCP+ CN++A C+ L+K PV P C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + ++ ++ + PI + I C + C TCC + + CCP P AVCC D HCCP+ C++ SCD Sbjct: 127 SYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC----------VKRKV---KVQTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQ---TPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 604 HSP 7 Score: 205.682 bits (522), Expect = 2.038e-56 Identity = 152/495 (30.71%), Postives = 215/495 (43.43%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-----LKEVVTKIKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKIPAISNLS-----------------------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPN-------------GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 G +SCCP+ CC D HCCP+ C++ TC + L + K +P S + P C DGS+C C + SY CCP + + CSD +HCCP + C+ D+ C K K+KV +V+C + S+C +TCC G + CCP AVCC DK HCCP++TVC++ A C S +L+ K K P + + C D ++ C G+TCC DG + CCP AVCC D + CCP C+++AG+C+ + S + + Q + V+ + C+DG TCCK GD + CCP A CC D +HCCP+ CNI C+ E + V+S PN + C TCC + + ++CCP P AVCC D HCCP+ C + SC+ Sbjct: 37 GGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGD-WACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCE 516 HSP 8 Score: 201.06 bits (510), Expect = 7.444e-55 Identity = 149/415 (35.90%), Postives = 196/415 (47.23%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-------VLKEVVTKIKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL-----IKTFQPNP---VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYS 1418 T DG ++CCP AVCC D HCCP +C++ G+C+ V K V I+ + A++ +S V C D C DGSTCC G + CCP AVCC D HCCP CN+ AG+CD V V K+ + + A S V C C + STCC G + CCP+S AVCC+D HCCP + CNL + +C +VV KI A S +L + D S+C +TCCLLS GCCPF AVCC D+ CCP+ C+L +C T+ + I++ +P P V V C G + C DG+TCC L + ++GCCP A CC D HCCP G CG GTC + + +S Sbjct: 655 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGSTCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKG--DVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQLTHIRSNKPQPSVVVKDVQC-GGGFSCHDGETCC-LTSQTTWGCCPSPKAVCCDDMQHCCPA----------------------------------GYKCGPGGTCISAGDLDWS 1031 HSP 9 Score: 195.667 bits (496), Expect = 4.599e-53 Identity = 135/458 (29.48%), Postives = 204/458 (44.54%), Query Frame = 3 Query: 405 IKLKVPASSILSVVC---PDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----LKEVVTKMKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-----------------------DSKTKKPSLLIKTFQP-------NPVNRVICPGAKYQ-------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 ++L V + + V+C P+ C G +CC G ++CCP+ CC D HCCP+ +C++ TC + L + K +P S + P C DGS+C C + SY CCP + + CSD +HCCP + C+ D+ C K K+K+ ++ C +G+S C TCC DG +GCCP AVCC DK+ CCP++TVC++ A C D K K+P T +P N++ A++Q C DG TCCK G + CCP A CC D IHCCP C++ G+C+ + ++ ++ + PI + + C + + C TCC + ++CCP P AVCC D HCCP C++ C+ + + P++ P Sbjct: 2 LRLTVCLAVVTLVICSQCPNNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 445
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 154.066 bits (388), Expect = 2.309e-42 Identity = 96/252 (38.10%), Postives = 130/252 (51.59%), Query Frame = 3 Query: 375 DSVLKEVVTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD 1064 + V + K K+ V S +S V C D + C DG+TCC G +ACCP AVCC D HCCP+ CN+ A C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP CN+ AG+CD V + K K+ + S+ S + P + ++ C G+TCC DG + CCP AVCC D + CCP CN++AG+CD Sbjct: 19 EKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 270 HSP 2 Score: 140.969 bits (354), Expect = 1.405e-37 Identity = 86/211 (40.76%), Postives = 110/211 (52.13%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD 833 T +G ++CCP AVCC D HCCP+ +CN+ C+ L + +V + ++ V + V C D + C DGSTCC G +ACCP AVCC D HCCP CN+ AG+CD V + K K+ V +S S V C D + C DGSTCC G +ACCP AVCC D HCCP CN+ AG+CD Sbjct: 60 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 270 HSP 3 Score: 130.568 bits (327), Expect = 8.192e-34 Identity = 81/248 (32.66%), Postives = 122/248 (49.19%), Query Frame = 3 Query: 852 VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSLLIKTFQPNPVNRVICPGAKYQ---------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 + K K+ + +S++S + P + ++ C G TCC +G + CCP AVCC D + CCP+ CN++A C+ T++P + Q VI G + C DG TCCK G + CCP A CC D IHCCP CN+ G+CD + ++ ++ + PI + + C + + C TCC + + ++CCP P AVCC D HCCP+ C++ SCD Sbjct: 26 IRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVI--GTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 270 HSP 4 Score: 51.9878 bits (123), Expect = 7.947e-7 Identity = 22/69 (31.88%), Postives = 35/69 (50.72%), Query Frame = 3 Query: 1347 IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 + C + + C TCC + ++CCP P AVCC D HCCP C++ C+ + + P++ P Sbjct: 43 VPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 111
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148]) HSP 1 Score: 239.965 bits (611), Expect = 1.338e-68 Identity = 154/420 (36.67%), Postives = 207/420 (49.29%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV--VTKIKLKVPASSI---------LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE--VVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVES--IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 S+ CCP AVCC D HCCP N+EC++ +G C S + ++K+ +V + + V C D + C DGSTCC +Y CC SAVCCSD HCCP T C+L C S+ E ++ +M + S V C + C D +TCC ++ + CCPY+ AVCC D HCCP C+ G+C + K + ++C D +++C TCC L G +GCCP AVCC+D L CCP+ C S G C KT R + Y C DGQTCC+L +GD +GCCP + A CC D HCCP C+ + + L K + E+ +KC + C TCC A+ + CCP AVCC DH HCCP +CS Sbjct: 142 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMP-AIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQC-DDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 554 HSP 2 Score: 226.868 bits (577), Expect = 5.306e-64 Identity = 151/413 (36.56%), Postives = 203/413 (49.15%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL-KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 D +Y CC SAVCCSD HCCP T C+L C S E ++ + S V C + C D +TCC ++ + CCPY+ AVCC D HCCP C+ G+C + K V C D + C + TCC + G + CCP AVCC+D HCCP+ C+ G C SK++ + K PA+++ + +EC D S C G TCC L+ G +GCCP + AVCC D CCP C S G C L KT + + + C+DGQTCC+L +GD +GCCP + A CC D HCCP C+ ++ + K +P L + ++C + C TCC A+ + CCP AVCC DH HCCP +CS Sbjct: 227 DHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFT-KTPALTHEARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 628 HSP 3 Score: 189.889 bits (481), Expect = 5.164e-51 Identity = 134/363 (36.91%), Postives = 183/363 (50.41%), Query Frame = 3 Query: 459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---------DSKLKEVVTKMKLKIPAISN--LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 S C D +C G ACCP + C D HCC + C+ D C +PAS+ +VVCPD +S+C +TCC ++ S+ CCP AVCC D HCCP N+ C++ G C SKL V LK+ + + + C DG + C G+TCC D +YGCC +AVCCSD L CCP T C+L C S+T + LL + + N+V C A C D TCC L + + +GCCPY+ A CC D IHCCP C + G+C +H + ++ L ++C + + C +K TCC + + CCP AVCC+DH HCCP +CS Sbjct: 63 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPC-DATTSCPDKNTCCHL-SSEKWGCCPYAQAVCCDDHIHCCPSGFTC--SGGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS 406 HSP 4 Score: 186.037 bits (471), Expect = 9.365e-50 Identity = 135/438 (30.82%), Postives = 174/438 (39.73%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYS-----------------------------------------------AATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCP 1427 G + CCP AVCC+D HCCP+ C+ +G C + + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ + E K PA+ + ++C D S C G TCC L+ G +GCCP + AVCC D CCP C S G C KT ++ + C DG TCC++ +G +GCCP A CCSD HCCPQ C+ +GTC ++ ++ P C + C TCCP + CCP Sbjct: 379 GKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGS----QCMIGEHSIPWFSKTPALKQKAKDVQCDDMYS-CADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPWYSKTPALKQEGNIVKCDDSFACKDGYTCCRMVSG-VWGCCPIEKCCQTHTPLLPLQKCCPSLPILALATCHVQDSVQDSCTRLQSTHWCRTAVCCSDHWHCCPQGFTCDA-RGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCP 803 HSP 5 Score: 162.54 bits (410), Expect = 1.031e-41 Identity = 140/478 (29.29%), Postives = 178/478 (37.24%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSN-----------------------------------------------AVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDK--IHCCPQNTVCNINKGTCDH-------QAEALEIKISPILVESIK-----CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G + CCP + AVCC D +HCCP C+ G C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + E K PA+ ++C D S CK G TCC + G +GCCP AVCCSD CCPQ C+ + P L P IC + C G TCC G + CCP + + I V ++ C Q EA+E S V+ ++ C + C TCC ++CC Y VCC D HCCP C + SC ++ Sbjct: 453 GDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQC--QKGEHSIPWYSKTPALKQEGNIVKC-DDSFACKDGYTCCRMVSGVWGCCPIEKCCQTHTPLLPLQKCCPSLPILALATCHVQDSVQDSCTRLQSTHWCRTAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSIC-DDTHTCPSGTTCCPGEGG-GWRCCPVEEVSKMVKRTVILLATACIVTLVSFSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCLNHGTSCSRS 919 HSP 6 Score: 149.443 bits (376), Expect = 2.215e-37 Identity = 110/343 (32.07%), Postives = 150/343 (43.73%), Query Frame = 3 Query: 639 LKVPASSILSVVCPDQSQCNDGSTCCAVAG----------------------------------------GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ-AEALEIKISPILVES----IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 L + S++ + +CPD S C + S CC + G G ACCP + C D HCC + C+ D C IPA + ++ CPDG S C T TCC++SD S+GCCP AVCC D + CCP N+ C++ G C S + K L + + RV C + C DG TCC+ +YGCC +A CCSD +HCCP T C++ C Q E + P + E + C + C K TCC +++ + CCPY AVCC DH HCCP+ +CS Sbjct: 7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAAEVVSRSLPMILSQTSCSGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLG-DEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS 332 HSP 7 Score: 63.5438 bits (153), Expect = 7.055e-10 Identity = 64/208 (30.77%), Postives = 83/208 (39.90%), Query Frame = 3 Query: 903 CPDGSSTCKTGATCCLL-SDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 CPDGS TC + CC L YGCCP + V P +L +T C G C D +C P G + CCP + C D HCC + C+ + C I ++ CP+G S C TCC ++ S+ CCP P AVCC DH HCCP+N+ C + C N Sbjct: 19 CPDGS-TCGEKSLCCELPGKKGYGCCPAAEVV------------------------SRSLPMILSQTS---------CSG----CPDEYSCVNTPEGGT-ACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC----------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISN 177
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148]) HSP 1 Score: 232.261 bits (591), Expect = 4.931e-67 Identity = 162/440 (36.82%), Postives = 214/440 (48.64%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL----KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI----LLKFPIINF 1547 S+ CCP AVCC D HCCP N+EC++ +G C S + KL K V C D + C DGSTCC +Y CC SAVCCSD HCCP T C+L C S+ E + ++PA S +Q C+ TCC + G + CCP AVCC+D HCCP+ C+ G C SK++ + K PA+++ + +EC D S C G TCC L+ G +GCCP + AVCC D CCP C S G C L KT + + + C+DGQTCC+L +GD +GCCP + A CC D HCCP C+ ++ + K +P L + ++C + C TCC A+ + CCP AVCCSDH HCCP +C L K P + F Sbjct: 142 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFT-KTPALTHEARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPF 567 HSP 2 Score: 200.675 bits (509), Expect = 1.673e-55 Identity = 141/395 (35.70%), Postives = 184/395 (46.58%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCP 1427 D +Y CC SAVCCSD HCCP T C+L C S E + ++PA S +Q C+ TCC + G + CCP AVCC+D HCCP+ C+ G C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + E + K PA+ + ++C D + +C G TCC L+ G +GCCP + AVCC D CCP C S C KT + + Y C+DGQTCC+L +GD +GCCP + A CCSD HCCPQ C+ +GTC ++ ++ P C + C TCCP + CCP Sbjct: 220 DHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQC--QKGEHSIPLFSKTPALRQETKYVKC-DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGD-WGCCPIAQAVCCSDHWHCCPQGFTCDA-RGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCP 598 HSP 3 Score: 190.274 bits (482), Expect = 8.774e-52 Identity = 139/436 (31.88%), Postives = 183/436 (41.97%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDK--IHCCPQNTVCNINKGTCDH-------QAEALEIKISPILVESIK-----CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 G + CCP AVCC+D HCCP+ C+ +G C + + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ + E K PA+ + ++C D S C G TCC L+ G +GCCP + AVCCSD CCPQ C+ + P L P IC + C G TCC G + CCP + + I V ++ C Q EA+E S V+ ++ C + C TCC ++CC Y VCC D HCCP C + SC ++ ++ Sbjct: 295 GKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGS----QCMIGEHSIPWFSKTPALKQKAKDVQCDDMYS-CADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSIC-DDTHTCPSGTTCCPGEGG-GWRCCPVEEVSKMVKRTVILLATACIVTLVSFSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCLNHGTSCSRSGSPRW 719 HSP 4 Score: 183.726 bits (465), Expect = 1.757e-49 Identity = 128/356 (35.96%), Postives = 175/356 (49.16%), Query Frame = 3 Query: 459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVES---IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 S C D +C G ACCP + C D HCC + C+ D C +PAS+ +VVCPD +S+C +TCC ++ S+ CCP AVCC D HCCP N+ C++ G C S + KL K + C DG + C G+TCC D +YGCC +AVCCSD L CCP T C+L C S+T + LL + + N+V C + +TCC+L +G +GCCP A CC+D +HCCP+ C ++G C ++ +P L ++C + C TCC A+ + CCP AVCC DH HCCP +CS Sbjct: 63 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKK----ETCCRLVSG-KWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 396 HSP 5 Score: 153.295 bits (386), Expect = 7.202e-39 Identity = 120/369 (32.52%), Postives = 163/369 (44.17%), Query Frame = 3 Query: 411 LKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA--LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 L + S++ + +CPD S C + S CC + G Y CCP + EVV++ L + S CPD+ C + G ACCP + C D HCC + C+ D C IPA + ++ CPDG S C T TCC++SD S+GCCP AVCC D + CCP N+ C++ G C S + K + + RV C + C DG TCC+ +YGCC +A CCSD +HCCP T C++ C Q L ++ I ES +K TCC + + CCP AVCC+DH HCCP +CS Sbjct: 7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSR-SLPMILSQTSCSGCPDEYSCVN------TPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS 322 HSP 6 Score: 115.161 bits (287), Expect = 2.959e-26 Identity = 91/316 (28.80%), Postives = 134/316 (42.41%), Query Frame = 3 Query: 639 LKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-DHQAEALEIKISPILVES-------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFPIIN 1544 L + S++ + +CPD S C + S CC + G Y CCP + EVV++ I + ++ S CPD S C +G CCP + C D CC + C+ C + + + V+CP + +C TCC + S+GCCP A CC D +HCCP N+ C++ +G C +Q + P V+S + C +G+ C TCC + +Y CC +AVCCSDH HCCP T+C L K C + +L + P I Sbjct: 7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSRSLPMILSQTSCS-GCPDEYS-------CVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYCIPASNQ-------------SAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIR 271
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148]) HSP 1 Score: 231.491 bits (589), Expect = 1.295e-66 Identity = 162/440 (36.82%), Postives = 214/440 (48.64%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL----KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI----LLKFPIINF 1547 S+ CCP AVCC D HCCP N+EC++ +G C S + KL K V C D + C DGSTCC +Y CC SAVCCSD HCCP T C+L C S+ E + ++PA S +Q C+ TCC + G + CCP AVCC+D HCCP+ C+ G C SK++ + K PA+++ + +EC D S C G TCC L+ G +GCCP + AVCC D CCP C S G C L KT + + + C+DGQTCC+L +GD +GCCP + A CC D HCCP C+ ++ + K +P L + ++C + C TCC A+ + CCP AVCCSDH HCCP +C L K P + F Sbjct: 162 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFT-KTPALTHEARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPF 587 HSP 2 Score: 199.904 bits (507), Expect = 3.510e-55 Identity = 141/396 (35.61%), Postives = 184/396 (46.46%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCP 1427 D +Y CC SAVCCSD HCCP T C+L C S E + ++PA S +Q C+ TCC + G + CCP AVCC+D HCCP+ C+ G C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + E + K PA+ + ++C D + +C G TCC L+ G +GCCP + AVCC D CCP C S C KT + + Y C+DGQTCC+L +GD +GCCP + A CCSD HCCPQ C+ +GTC ++ ++ P C + C TCCP + CCP Sbjct: 239 VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQC--QKGEHSIPLFSKTPALRQETKYVKC-DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGD-WGCCPIAQAVCCSDHWHCCPQGFTCDA-RGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCP 618 HSP 3 Score: 189.504 bits (480), Expect = 1.849e-51 Identity = 139/431 (32.25%), Postives = 181/431 (42.00%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDK--IHCCPQNTVCNINKGTCDH-------QAEALEIKISPILVESIK-----CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G + CCP AVCC+D HCCP+ C+ +G C + + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ + E K PA+ + ++C D S C G TCC L+ G +GCCP + AVCCSD CCPQ C+ + P L P IC + C G TCC G + CCP + + I V ++ C Q EA+E S V+ ++ C + C TCC ++CC Y VCC D HCCP C + SC ++ Sbjct: 315 GKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGS----QCMIGEHSIPWFSKTPALKQKAKDVQCDDMYS-CADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSIC-DDTHTCPSGTTCCPGEGG-GWRCCPVEEVSKMVKRTVILLATACIVTLVSFSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCLNHGTSCSRS 734 HSP 4 Score: 183.341 bits (464), Expect = 3.349e-49 Identity = 128/356 (35.96%), Postives = 175/356 (49.16%), Query Frame = 3 Query: 459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVES---IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 S C D +C G ACCP + C D HCC + C+ D C +PAS+ +VVCPD +S+C +TCC ++ S+ CCP AVCC D HCCP N+ C++ G C S + KL K + C DG + C G+TCC D +YGCC +AVCCSD L CCP T C+L C S+T + LL + + N+V C + +TCC+L +G +GCCP A CC+D +HCCP+ C ++G C ++ +P L ++C + C TCC A+ + CCP AVCC DH HCCP +CS Sbjct: 83 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKK----ETCCRLVSG-KWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 416 HSP 5 Score: 152.91 bits (385), Expect = 9.678e-39 Identity = 120/369 (32.52%), Postives = 163/369 (44.17%), Query Frame = 3 Query: 411 LKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA--LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 L + S++ + +CPD S C + S CC + G Y CCP + EVV++ L + S CPD+ C + G ACCP + C D HCC + C+ D C IPA + ++ CPDG S C T TCC++SD S+GCCP AVCC D + CCP N+ C++ G C S + K + + RV C + C DG TCC+ +YGCC +A CCSD +HCCP T C++ C Q L ++ I ES +K TCC + + CCP AVCC+DH HCCP +CS Sbjct: 27 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSR-SLPMILSQTSCSGCPDEYSCVN------TPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS 342 HSP 6 Score: 124.02 bits (310), Expect = 3.770e-29 Identity = 98/295 (33.22%), Postives = 130/295 (44.07%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA--SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSV--VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS-----------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPN 1112 G + CCP + AVCC D +HCCP C+ ++ ++ E K PA V C D C DG TCC +A G + CCP + AVCCSD HCCPQ C+ GTC L + KVPA +C D C G+TCC GG + CCP V KR T C + + S +++ L+ AI L D C G TCC G + CC ++ VCC D + CCP VC L+ GT S++ P ++ P+ Sbjct: 463 GDWGCCPIAQAVCCDDHEHCCPPGYTCSGSQ----CMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDA-RGTC--VLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCPVEE-VSKMVKRTVILLATACIVTLVS-FSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVC-LNHGTSCSRSGSPRWDGQSGSPH 747 HSP 7 Score: 115.161 bits (287), Expect = 3.110e-26 Identity = 92/327 (28.13%), Postives = 137/327 (41.90%), Query Frame = 3 Query: 606 SKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-DHQAEALEIKISPILVES-------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFPIIN 1544 +K + L + S++ + +CPD S C + S CC + G Y CCP + EVV++ I + ++ S CPD S T +G CCP + C D CC + C+ C + + + V+CP + +C TCC + S+GCCP A CC D +HCCP N+ C++ +G C +Q + P V+S + C +G+ C TCC + +Y CC +AVCCSDH HCCP T+C L K C + +L + P I Sbjct: 16 NKAARMGPPWFLLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSRSLPMILSQTSCS-GCPDEYSCVNT-------PEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYCIPASNQ-------------SAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIR 291
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148]) HSP 1 Score: 223.402 bits (568), Expect = 6.987e-63 Identity = 158/462 (34.20%), Postives = 211/462 (45.67%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV--VTKIKLKVPASSI---------LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL-KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-------TKKPSLLIKTFQPNPVNRVICPGAK------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCP---------------------------QNTVCNINKGTCDHQAEALEIKISPIL-----VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 S+ CCP AVCC D HCCP N+EC++ +G C S + ++K+ +V + + V C D + C DGSTCC +Y CC SAVCCSD HCCP T C+L C S+ E ++ + S V C + C D +TCC ++ + CCPY+ AVCC D HCCP C+ G+C + K + ++C D +++C TCC L G +GCCP AVCC+D L CCP+ C S G C TK P + + + V+ Y C DGQTCC+L +GD +GCCP + A CC D HCCP Q T C G D L + SP + + +KC + C TCC A+ + CCP AVCC DH HCCP +CS Sbjct: 142 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQC-DDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPMVFFLSLSLLSILPVVSVARDVECDDMYSCPDGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETACARRCGD-DEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 596 HSP 2 Score: 211.46 bits (537), Expect = 1.133e-58 Identity = 161/455 (35.38%), Postives = 213/455 (46.81%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL-KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVV---TKMKLKI----------PAIS-NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-------TKKPSLLIKTF---------QPNPV----NRVICPG--AKY-------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 D +Y CC SAVCCSD HCCP T C+L C S E ++ + S V C + C D +TCC ++ + CCPY+ AVCC D HCCP C+ G+C + K V C D + C + TCC + G + CCP AVCC+D HCCP+ C+ G C SK++ + TK + P +S +EC D S C G TCC L+ G +GCCP + AVCC D CCP C S G C +K P+L +T P P+ + ICP AKY C+DGQTCC+L +GD +GCCP + A CC D HCCP C+ ++ + K +P L + ++C + C TCC A+ + CCP AVCC DH HCCP +CS Sbjct: 226 VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFTKTPMVFFLSLSLLSILPVVSVARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETACARRCGDDEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 670 HSP 3 Score: 190.274 bits (482), Expect = 3.352e-51 Identity = 138/385 (35.84%), Postives = 192/385 (49.87%), Query Frame = 3 Query: 459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---------DSKLKEVVTKMKLKIPAISN--LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF---PIINF 1547 S C D +C G ACCP + C D HCC + C+ D C +PAS+ +VVCPD +S+C +TCC ++ S+ CCP AVCC D HCCP N+ C++ G C SKL V LK+ + + + C DG + C G+TCC D +YGCC +AVCCSD L CCP T C+L C S+T + LL + + N+V C A C D TCC L + + +GCCPY+ A CC D IHCCP C + G+C +H + ++ L ++C + + C +K TCC + + CCP AVCC+DH HCCP +CS S ++ + F P++ F Sbjct: 63 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPC-DATTSCPDKNTCCHL-SSEKWGCCPYAQAVCCDDHIHCCPSGFTC--SGGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKMEHSIPWFTKTPMVFF 428 HSP 4 Score: 169.088 bits (427), Expect = 5.283e-44 Identity = 136/430 (31.63%), Postives = 166/430 (38.60%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCP---------------------------QNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLS-----------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-------DSKTKKPSLLIKTFQPN-------PVNRVICPG------------------------------------AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGT 1289 G + CCP + AVCC D +HCCP Q T C G + + P S V C D C DG TCC +A G + CCP + AVCC D HCCP C+ C + K V C D C DG TCC +A G + CCP + AVCC D HCCP C+ G C + K LK NL+ ++C D S CK G TCC + G +GCCP AVCCSD CCPQ C+ + GTC TK P+L P CPG ++Y C DGQTCC+ G + CC Y+ CC D +HCCP VC +N GT Sbjct: 466 GDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETACARRCGDDEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPWYSKTPALKQEGKCNLANTPVNVFAGNIVKC-DDSFACKDGYTCCRMVSGVWGCCPIEKAVCCSDHWHCCPQGFTCD-ARGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCPVEEKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRG-LGGVWNCCVYTQGVCCPDMVHCCPYGYVC-LNHGT 887 HSP 5 Score: 148.288 bits (373), Expect = 4.863e-37 Identity = 110/343 (32.07%), Postives = 150/343 (43.73%), Query Frame = 3 Query: 639 LKVPASSILSVVCPDQSQCNDGSTCCAVAG----------------------------------------GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ-AEALEIKISPILVES----IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490 L + S++ + +CPD S C + S CC + G G ACCP + C D HCC + C+ D C IPA + ++ CPDG S C T TCC++SD S+GCCP AVCC D + CCP N+ C++ G C S + K L + + RV C + C DG TCC+ +YGCC +A CCSD +HCCP T C++ C Q E + P + E + C + C K TCC +++ + CCPY AVCC DH HCCP+ +CS Sbjct: 7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAAEVVSRSLPMILSQTSCSGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLG-DEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS 332 HSP 6 Score: 62.7734 bits (151), Expect = 1.212e-9 Identity = 64/208 (30.77%), Postives = 83/208 (39.90%), Query Frame = 3 Query: 903 CPDGSSTCKTGATCCLL-SDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 CPDGS TC + CC L YGCCP + V P +L +T C G C D +C P G + CCP + C D HCC + C+ + C I ++ CP+G S C TCC ++ S+ CCP P AVCC DH HCCP+N+ C + C N Sbjct: 19 CPDGS-TCGEKSLCCELPGKKGYGCCPAAEVV------------------------SRSLPMILSQT---------SCSG----CPDEYSCVNTPEGGT-ACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC----------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISN 177
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832]) HSP 1 Score: 264.618 bits (675), Expect = 1.905e-80 Identity = 167/448 (37.28%), Postives = 232/448 (51.79%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-----KLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE----IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPII 1541 +T G+ SCCP+S V C D HCCPQ C+ + +C ++ + + +V CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S L + K S SVVCPD ++QC D STCC + G Y CCP +A+CCSD HCCPQ+TVC+L C SK T + K+P ++C D +C G TCC L+ G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P + + C D TCCKL +GD +GCCP A CCSD HCCPQ C + +G C D LE + +P+ + I C + C TCCPS S++CC P+AVCC D HCCP +C++ ++C+K++ ++ P++ Sbjct: 88 LTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKC-DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGD-WGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVL 518 HSP 2 Score: 264.233 bits (674), Expect = 2.871e-80 Identity = 165/451 (36.59%), Postives = 224/451 (49.67%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 + DGS+ CCP A CC D+ HCCP C+L C ++LK+ + K S SVVCPD ++QC D STCC + G Y CCP +A+CCSD HCCPQ+TVC+L C SK T + K+P + V C + C +G TCC + G++ CCP++ AVCC D HCCP C+ + GTC+ +K+V+ ++L P I C D + C T TCC L+ G +GCCP AVCCSD CCPQ C L+ G C + L K P + + C C GQTCC G S+ CC A CC D+ HCCP CN+ TC+ + ++ + L V +++C G C TCC + ++CCPY VCC D HCCP CS C + + ++ + P Sbjct: 153 IMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQ-KTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPC-DDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDP 596 HSP 3 Score: 219.55 bits (558), Expect = 1.948e-63 Identity = 141/374 (37.70%), Postives = 184/374 (49.20%), Query Frame = 3 Query: 426 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS---------KLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---QAEALEIKISP-------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 S L C C G +C G+ +CCP+S V C D HCCPQ C+ D +C ++ + + +V CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S K T + +P S+ CPD + C +TCC L G YGCCP NA+CCSD L CCPQ+TVC+L C SK LL K PV V C + C +G TCC+L G ++GCCP++ A CC D IHCCP C+ KGTC+ Q ++ I+P IL C + + C TCC + + CCP P AVCCSD+ HCCP +C Sbjct: 67 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLP----FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTK-LPGYPVKEVKC-DMEVSCPEGYTCCRLNTG-AWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC 421 HSP 4 Score: 186.422 bits (472), Expect = 2.551e-51 Identity = 113/299 (37.79%), Postives = 148/299 (49.50%), Query Frame = 3 Query: 654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNR-------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--DHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 S L C C G +C G+ +CCP+S V C D HCCPQ C+ D +C ++ +++CP C ATCC++ DGS+GCCP A CC D++ CCP C+L C S T +LL K F NR V+CP AK QC D TCC+LP G YGCCP A CCSD +HCCPQ+TVC++ + C + L K+ V+ +KC C + TCC ++ CCP+ AVCC DH HCCP C +C+ IL Sbjct: 67 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLL-KKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTG-KYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGIL 351
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832]) HSP 1 Score: 110.538 bits (275), Expect = 6.163e-27 Identity = 78/270 (28.89%), Postives = 117/270 (43.33%), Query Frame = 3 Query: 348 ECNLNKGTCD------SVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASS-----ILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKI-PAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPV 1118 +C+ KGTC+ +K+V+ ++L P C D ++C +TCC + G + CCP C K +V ++ K+PA I + C + C G TCC GS+ACC AVCC D++HCCP CN+ A TC+ + + + L + P + N +EC +G C TCC S G + CCP+ VCC D CCP C+ C K + + ++ P P+ Sbjct: 3 QCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEGYC----------------------QKGDTMVAGLE-KIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGN--VECGEG-HFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDPVPRPL 246 HSP 2 Score: 104.375 bits (259), Expect = 9.885e-25 Identity = 75/258 (29.07%), Postives = 109/258 (42.25%), Query Frame = 3 Query: 807 CNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 C+ + GTC+ +K+V+ ++L P I C D + C T TCC L+ G +GCCP C + AG K P+ Q + + C C GQTCC G S+ CC A CC D+ HCCP CN+ TC+ + ++ + L V +++C G C TCC + ++CCPY VCC D HCCP CS C + + ++ + P Sbjct: 4 CHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPC-DDFTRCPTNNTCCKLNSGDWGCCPIPEGYCQKGD----------TMVAGL----EKIPARQTTPLQ---IGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDP 241 HSP 3 Score: 99.7525 bits (247), Expect = 3.493e-23 Identity = 67/207 (32.37%), Postives = 91/207 (43.96%), Query Frame = 3 Query: 312 CSDKQHCCPQNTECNLNKGTC-------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL 893 C D C NT C LN G D+++ + + I + C + C G TCC GS+ACC AVCC D++HCCP CN+ A TC+ + + + L + + +V C + C+D TCC + G +ACCPY VCC D RHCCP C+ C K K M L+ P L Sbjct: 42 CDDFTRCPTNNTCCKLNSGDWGCCPIPEGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTL-GPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK-KIPRWDMFLRDPVPRPL 246 HSP 4 Score: 87.4261 bits (215), Expect = 5.727e-19 Identity = 49/131 (37.40%), Postives = 66/131 (50.38%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSIL 665 GS++CC AVCC D+QHCCP CN+ TC+ + + + L + + +V C + C+D TCC + G +ACCPY VCC D RHCCP C+ C K K M L+ P L Sbjct: 118 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTL-GPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK-KIPRWDMFLRDPVPRPL 246
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832]) HSP 1 Score: 108.612 bits (270), Expect = 1.666e-25 Identity = 69/181 (38.12%), Postives = 95/181 (52.49%), Query Frame = 3 Query: 459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASS-----ILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKI-PAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPF 983 ++C +TCC + G + CCP AVCCSD +HCCPQ C L G C K +V ++ K+PA I + C + C G TCC GS+ACC AVCC D++HCCP CN+ A TC+ + + + L + P + N +EC +G C TCC S G + CCP+ Sbjct: 3 TRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQ-KGDTMVAGLE-KIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGN--VECGEG-HFCHDNQTCCKDSAGVWACCPY 177 HSP 2 Score: 107.071 bits (266), Expect = 6.281e-25 Identity = 63/165 (38.18%), Postives = 85/165 (51.52%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASS-----ILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPY 752 G + CCP AVCCSD QHCCPQ C L +G C + + K+PA I + C + C G TCC GS+ACC AVCC D++HCCP CN+ A TC+ + + + L + + +V C + C+D TCC + G +ACCPY Sbjct: 17 GDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQK--GDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTL-GPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPY 177 HSP 3 Score: 104.76 bits (260), Expect = 3.050e-24 Identity = 73/182 (40.11%), Postives = 96/182 (52.75%), Query Frame = 3 Query: 687 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTK--KPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPY 1214 ++C +TCC + G + CCP AVCCSD +HCCPQ C L G C K +V ++ KIPA ++ D ++C G TCC GS+ CC +AVCC D+ CCP CN+ A TC+ +P +L+ T P V V C G + C D QTCCK AG + CCPY Sbjct: 3 TRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQ-KGDTMVAGLE-KIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLL-TLGPK-VGNVEC-GEGHFCHDNQTCCKDSAG-VWACCPY 177 HSP 4 Score: 94.3597 bits (233), Expect = 1.204e-20 Identity = 54/139 (38.85%), Postives = 79/139 (56.83%), Query Frame = 3 Query: 1149 QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE----IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPII 1541 +C TCCKL +GD +GCCP A CCSD HCCPQ C + +G C D LE + +P+ + I C + C TCCPS S++CC P+AVCC D HCCP +C++ ++C+K++ ++ P++ Sbjct: 4 RCPTNNTCCKLNSGD-WGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVL 140 HSP 5 Score: 93.2041 bits (230), Expect = 2.767e-20 Identity = 64/178 (35.96%), Postives = 85/178 (47.75%), Query Frame = 3 Query: 918 STCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNP--VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPY 1430 + C T TCC L+ G +GCCP AVCCSD CCPQ C L+ G C + L I Q P + + C C GQTCC G S+ CC A CC D+ HCCP CN+ TC+ + ++ + L V +++C G C TCC + ++CCPY Sbjct: 3 TRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPY 177
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832]) HSP 1 Score: 96.6709 bits (239), Expect = 2.154e-22 Identity = 61/174 (35.06%), Postives = 80/174 (45.98%), Query Frame = 3 Query: 654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNR-------VICPGAKYQC 1154 S L C C G +C G+ +CCP+S V C D HCCPQ C+ D +C ++ +++CP C ATCC++ DGS+GCCP A CC D++ CCP C+L C S T +LL K F NR V+CP AK QC Sbjct: 54 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLL-KKFPAQKTNRAVSLPFSVVCPDAKTQC 214 HSP 2 Score: 85.1149 bits (209), Expect = 1.997e-18 Identity = 46/123 (37.40%), Postives = 63/123 (51.22%), Query Frame = 3 Query: 924 CKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC 1292 C G +C L G+ CCPFS V C D CCPQ C+ +C + NP+ V CPG++++C D TCC + G S+GCCP A+CC D++HCCP C++ C Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSD-----------NPLGAVQCPGSQFECPDSATCCIMVDG-SWGCCPMPQASCCEDRVHCCPHGASCDLVHTRC 177 HSP 3 Score: 82.8037 bits (203), Expect = 1.446e-17 Identity = 54/152 (35.53%), Postives = 74/152 (48.68%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-----KLKEVVTKMKLKVPASSILSVVCPD-QSQC 695 +T G+ SCCP+S V C D HCCPQ C+ + +C ++ + + +V CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S L + K S SVVCPD ++QC Sbjct: 75 LTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQC 214 HSP 4 Score: 71.2478 bits (173), Expect = 1.137e-13 Identity = 43/127 (33.86%), Postives = 58/127 (45.67%), Query Frame = 3 Query: 1173 CKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFP 1535 C L + CCP+S C D HCCPQ C+ + +C ++S + +++CP C TCC + S+ CCP P A CC D HCCP+ SC L C +L KFP Sbjct: 73 CLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC--------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFP 191
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28799|GRN_HUMAN (Progranulin OS=Homo sapiens OX=9606 GN=GRN PE=1 SV=2) HSP 1 Score: 265.003 bits (676), Expect = 9.415e-80 Identity = 165/449 (36.75%), Postives = 223/449 (49.67%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI-------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV-------ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 V DGS+ CCP A CC D+ HCCP C+L C + + K+PA SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA ++ V C + C DG TCC + G++ CCP++ AVCC D HCCP C+ GTC+ +V K L +P L + P D S+C + TCC L+ G +GCCP AVCCSD CCPQ C ++ G C ++ S ++ + P R I C GQTCC G S+ CC A CC D+ HCCP CN+ +C+ + A + SP + V+ ++C G C TCC ++CCPY VCC+D HCCP C+ C + ++ Sbjct: 141 VMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRC--ITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 580 HSP 2 Score: 263.848 bits (673), Expect = 2.453e-79 Identity = 164/445 (36.85%), Postives = 229/445 (51.46%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFP 1535 T G+ SCCP+ AV C D HCCP+ C+ + +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L C L + + + + SV+CPD +S+C DGSTCC + G Y CCP +A CCSD HCCPQ+TVC+L C SK + T + K+PA + ++C D +C G TCC L G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P + R + C TCC+L +G+ +GCCP A CCSD HCCPQ C + +G C +E + ++ P S+ P C Q TCCPS S++CC P+AVCC D HCCP +C++ +SC+K ++ P Sbjct: 75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQP 504 HSP 3 Score: 234.187 bits (596), Expect = 3.966e-68 Identity = 144/377 (38.20%), Postives = 193/377 (51.19%), Query Frame = 3 Query: 408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 K S L C + C+ G +C G+ +CCP+ AV C D HCCP+ C+ D +C + +S+ ++ CPD Q +C D STCC + GS+ CCP A CC D+ HCCP C+L C + K++ + + A+S+ S+ CPD S C G+TCC L G YGCCP NA CCSD L CCPQ+TVC+L C SK + L+ + V V C + C DG TCC+L +G ++GCCP++ A CC D IHCCP C+ KGTC+ HQ +E + + L + C N S C TCC + + CCP P AVCCSDH HCCP +C Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 410
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28798|GRN_MOUSE (Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 SV=2) HSP 1 Score: 264.618 bits (675), Expect = 9.720e-80 Identity = 167/448 (37.28%), Postives = 232/448 (51.79%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-----KLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE----IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPII 1541 +T G+ SCCP+S V C D HCCPQ C+ + +C ++ + + +V CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S L + K S SVVCPD ++QC D STCC + G Y CCP +A+CCSD HCCPQ+TVC+L C SK T + K+P ++C D +C G TCC L+ G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P + + C D TCCKL +GD +GCCP A CCSD HCCPQ C + +G C D LE + +P+ + I C + C TCCPS S++CC P+AVCC D HCCP +C++ ++C+K++ ++ P++ Sbjct: 75 LTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKC-DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGD-WGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVL 505 HSP 2 Score: 264.233 bits (674), Expect = 1.420e-79 Identity = 165/451 (36.59%), Postives = 224/451 (49.67%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 + DGS+ CCP A CC D+ HCCP C+L C ++LK+ + K S SVVCPD ++QC D STCC + G Y CCP +A+CCSD HCCPQ+TVC+L C SK T + K+P + V C + C +G TCC + G++ CCP++ AVCC D HCCP C+ + GTC+ +K+V+ ++L P I C D + C T TCC L+ G +GCCP AVCCSD CCPQ C L+ G C + L K P + + C C GQTCC G S+ CC A CC D+ HCCP CN+ TC+ + ++ + L V +++C G C TCC + ++CCPY VCC D HCCP CS C + + ++ + P Sbjct: 140 IMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQ-KTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPC-DDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDP 583 HSP 3 Score: 219.55 bits (558), Expect = 1.079e-62 Identity = 141/374 (37.70%), Postives = 184/374 (49.20%), Query Frame = 3 Query: 426 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS---------KLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---QAEALEIKISP-------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 S L C C G +C G+ +CCP+S V C D HCCPQ C+ D +C ++ + + +V CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S K T + +P S+ CPD + C +TCC L G YGCCP NA+CCSD L CCPQ+TVC+L C SK LL K PV V C + C +G TCC+L G ++GCCP++ A CC D IHCCP C+ KGTC+ Q ++ I+P IL C + + C TCC + + CCP P AVCCSD+ HCCP +C Sbjct: 54 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLP----FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTK-LPGYPVKEVKC-DMEVSCPEGYTCCRLNTG-AWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC 408 HSP 4 Score: 186.422 bits (472), Expect = 1.501e-50 Identity = 113/299 (37.79%), Postives = 148/299 (49.50%), Query Frame = 3 Query: 654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNR-------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--DHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 S L C C G +C G+ +CCP+S V C D HCCPQ C+ D +C ++ +++CP C ATCC++ DGS+GCCP A CC D++ CCP C+L C S T +LL K F NR V+CP AK QC D TCC+LP G YGCCP A CCSD +HCCPQ+TVC++ + C + L K+ V+ +KC C + TCC ++ CCP+ AVCC DH HCCP C +C+ IL Sbjct: 54 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLL-KKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTG-KYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGIL 338
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P23785|GRN_RAT (Progranulin OS=Rattus norvegicus OX=10116 GN=Grn PE=1 SV=3) HSP 1 Score: 263.462 bits (672), Expect = 2.527e-79 Identity = 167/454 (36.78%), Postives = 226/454 (49.78%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD------SKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV-------ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 + DGS+ CCP A CC D+ HCCP C+L C S +LK+ + + AS SVVCPD ++QC D STCC + G Y CCP +A+CCSD HCCPQ+TVC+L C SK + T + K+P + V C + C DG TCC + G++ CCP++ AVCC D HCCP C+ + GTC+ +K+V + L P I + C D SS C + TCC LS G +GCCP AVCC D CCPQ C + G C +K ++ + PV + I C GQTCC G S+ CC A CC D+ HCCP CN+ TC+ A +++ + V +++C G C +CC + ++CCPY VCC D HCCP CS C + ++ I+ P Sbjct: 140 IMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNRAVAS--FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--DYTTDLMTKLPGYPVNEVKCDLEVSCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFSS-CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYC----QKGDRMVAGLEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAGSVQPSMDLTFGSKVGNVECGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRKKTPRWDILLRDP 582 HSP 2 Score: 257.299 bits (656), Expect = 5.858e-77 Identity = 168/451 (37.25%), Postives = 235/451 (52.11%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ----PNPV---NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE---IKISPILVES-IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 +T G+ SCCP+S V C D QHCCP+ C+ + +C + ++ ++ CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S LK+ + + AS SVVCPD ++QC D STCC + G Y CCP +A+CCSD HCCPQ+TVC+L C SK + T + K+P ++C D +C G TCC L+ G++GCCPF+ AVCC D + CCP C+ GTC+ + + K P+P N V C C TCC+L +GD +GCCP A CC D HCCPQ C +++G C D LE ++ + +L I C + C TCCPS S++CC P+AVCC D HCCP +C++ ++C+K+ P ++ Sbjct: 75 LTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLLGAVQ------------CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNRAVAS--FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--DYTTDLMTKLPGYPVNEVKC-DLEVSCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFS-SCPSNNTCCRLSSGD-WGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYCQKGDRMVAGLEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAGSVQPSMDL 505 HSP 3 Score: 226.483 bits (576), Expect = 2.159e-65 Identity = 146/396 (36.87%), Postives = 197/396 (49.75%), Query Frame = 3 Query: 417 VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD----------HQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPI 1538 + S L C + C DG +C G+ +CCP+S V C D +HCCP+ C+ D +C ++ S + +V CP Q +C D +TCC + GS+ CCP A CC D+ HCCP C+L C S LK+ + + A+++ S+ CPD + C +TCC L G YGCCP NA+CCSD L CCPQ+TVC+L C SK L+ K PVN V C + C DG TCC+L G ++GCCP++ A CC D IHCCP C+ GTC+ +L + IL + C + S C TCC ++ + CCP P AVCC DH HCCP C ++ C K L K P+ Sbjct: 51 IITSRRLDGSCQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCS------------QISDSLLGAVQCPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNR--AVASFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKDYTTDLMTK-LPGYPVNEVKC-DLEVSCPDGYTCCRLNTG-AWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYCQKGDRMVAGLEKMPV 428 HSP 4 Score: 173.326 bits (438), Expect = 8.423e-46 Identity = 104/292 (35.62%), Postives = 144/292 (49.32%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPV 1118 G++ CCP++ AVCC D HCCP +C+ GTC+ +K+V + L P V C D S C +TCC ++ G + CCP AVCC D +HCCPQ C +D G C + V K+ V +++L + C + C G TCC GS+ACC AVCC D++HCCP CN+ A TC+ V M L + ++EC G C +CC S G + CCP+ VCC D CCP C+ C KT + +L++ P P+ Sbjct: 299 GAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYCQKGDRMVAGLEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAGSVQPSMDLTFGSKVG-NVECGAG-HFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRKKTPRWDILLRDPAPRPL 587 HSP 5 Score: 115.546 bits (288), Expect = 7.256e-26 Identity = 86/264 (32.58%), Postives = 116/264 (43.94%), Query Frame = 3 Query: 801 TVCNLDAGT-----CDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-DHQAEALEIKISP-------ILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFP 1535 C LD G C+ L ++ + CPDG S C L G+ CCPFS V C D CCP+ C+ +C + SLL V CPG++++C D TCC + G S+GCCP A+CC D++HCCP C++ C +K P + S+ CP+ + C TCC Y CCP PNA+CCSDH HCCP +T C L C +++ K P Sbjct: 28 VACCLDQGGANYSCCNPLLDTWPIITSRRLDGSCQIRDHCPDGYS-------CLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISD--SLL---------GAVQCPGSQFECPDSATCCIMIDG-SWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNRAVASFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKDYTTDLMTKLP 272
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28797|GRN_CAVPO (Progranulin OS=Cavia porcellus OX=10141 GN=GRN PE=1 SV=2) HSP 1 Score: 224.172 bits (570), Expect = 2.750e-64 Identity = 154/459 (33.55%), Postives = 219/459 (47.71%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVV-CPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL--KEVVTKMKLK-----------------VPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-------------------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514 +T G+ +CCP+S A+ C D HCCP C+ + GTC ++ P +L V CP + +C D STCC + GS+ CCP A CC D+ HCCP C+L C + L + TK+ + +PA+ SV+CPD +SQC D +TCC +A G Y CCP +A+CCSD HCCPQ+TVC+L C S+ K + K+P+ + +EC D +C G TCC L G +GCCPF AVCC D + CCP+ C+ TC+ + KT P P+ I C+ G CC+L +G+ +GCCP S + + C C + + A + +S + C + C TCCP ++CC P+AVCC D HCCP +C++ +SC+K Sbjct: 75 LTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC------------IQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK--AKTLLTKLPSWTVWDVEC-DQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPPSPPGPLRSEISCDEVVSCAPGNICCRLASGE-WGCCP-------SSEGYLCMAGERCQVGDRLAPEKMAAHLMSLS--QTTDVGCDQHASCPVGQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSCEK 508 HSP 2 Score: 220.32 bits (560), Expect = 6.945e-63 Identity = 154/468 (32.91%), Postives = 207/468 (44.23%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLK-------------------VPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS-------------------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCC-KLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVES------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC-SLNTKSCDKNILLKF 1532 DGS+ CCP A CC D+ HCCP C+L C + L KL +PA+ SV+CPD +SQC D +TCC +A G Y CCP +A+CCSD HCCPQ+TVC+L C S+ K + K+P+ ++ V C + C +G TCC + G + CCP+ AVCC D HCCP+ C+ + TC+ L +V K I C D +C G CC L+ G +GCCP S C C G + K + L+ Q V C GQTCC KL G + CC A CC D HCCP CN+ +C+ A+ + +P+ V S + C + C + TCC + ++CCP+ VCC D HCCP C S T+ K LL + Sbjct: 144 DGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK--AKTLLTKLPSWTVWDVECDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPPSPPGPLRSEISC-DEVVSCAPGNICCRLASGEWGCCPSSEGYLCMAGERC---------QVGDRLAPEKMAAHLMSLSQTTDVGC----DQHASCPVGQTCCPKL--GGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSCEKAADGAHLA-APLAVGSTGGVMDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKSLLHW 592 HSP 3 Score: 193.741 bits (491), Expect = 3.869e-53 Identity = 124/320 (38.75%), Postives = 163/320 (50.94%), Query Frame = 3 Query: 405 IKLKVPA-SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV-CPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL--KEVVTKMKLK-----------------IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH 1298 + L+ A S L C + C G +C A G+ ACCP+S A+ C D HCCP C+ D GTC ++ P +L V CP + +C D STCC + GS+ CCP A CC D+ HCCP C+L C + L + TK+ + +PA S+ CPD S C TCCLL+ G YGCCP NA+CCSD L CCPQ+TVC+L C S+ K +LL K V V C + C +GQTCC+L +G +GCCP+ A CC D +HCCP+ C+ K TC+ Sbjct: 46 VDLRTTALSGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC------------IQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTK-LPSWTVWDVEC-DQEVSCPEGQTCCRLQSG-KWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQ 350 HSP 4 Score: 188.348 bits (477), Expect = 4.479e-51 Identity = 117/323 (36.22%), Postives = 161/323 (49.85%), Query Frame = 3 Query: 654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL-SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNL-------SAGTCDSKTKKPSLLIK--TFQPNPV-----------NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--DHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 S L C + C G +C A G+ ACCP+S A+ C D HCCP C+ D GTC ++ P I L +++CP G C +TCC + DGS+GCCP A CC D++ CCP C+L + G+ TK P+ + PV VICP ++ QC D TCC L +G+ YGCCP A CCSD +HCCPQ+TVC++ + C ++A+ L K+ V ++C C + TCC + + CCP+P AVCC DH HCCP C +C++ LL+ P P Sbjct: 54 SGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC------------IQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGE-YGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTKLPSWTVWDVECDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQG-LLQVPWAQKTP 362 HSP 5 Score: 128.257 bits (321), Expect = 4.199e-30 Identity = 85/254 (33.46%), Postives = 119/254 (46.85%), Query Frame = 3 Query: 861 MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC------------------DHQAEALEIKISPILV-----ESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFP 1535 + L+ A+S + C G +C L + G+ CCPFS A+ C D CCP C+ GTC ++P + + + V CPG +++C D TCC + G S+GCCP A+CC D++HCCP C++ C ++ +SP L+ S+ CP+ S C TCC A+ Y CCP PNA+CCSDH HCCP +T C L C K +L K P Sbjct: 46 VDLRTTALSGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC---IQRPDIHL-------LGAVQCPGGEFECPDSSTCCHMLDG-SWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTKLP 288
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|Q54QR7|GRN_DICDI (Granulin OS=Dictyostelium discoideum OX=44689 GN=grn PE=3 SV=1) HSP 1 Score: 63.5438 bits (153), Expect = 7.818e-11 Identity = 31/65 (47.69%), Postives = 39/65 (60.00%), Query Frame = 3 Query: 1344 SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538 S+KCP+GSLC TCC +++ SY+CCP PNA CCSD HCCP +C C L+F Sbjct: 64 SVKCPDGSLCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNICKPQQGLRFSF 128 HSP 2 Score: 58.5362 bits (140), Expect = 3.682e-9 Identity = 32/69 (46.38%), Postives = 41/69 (59.42%), Query Frame = 3 Query: 627 TKMKLKVPASSIL-SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 830 TK L++ + SV CPD S C + +TCC+ + GSYACCP +A CCSDK+HCCP C C Sbjct: 50 TKKSLELTETQDFGSVKCPDGSLCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNIC 118 HSP 3 Score: 58.151 bits (139), Expect = 5.266e-9 Identity = 32/69 (46.38%), Postives = 41/69 (59.42%), Query Frame = 3 Query: 399 TKIKLKVPASSIL-SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 602 TK L++ + SV CPD S C + +TCC+ + GSYACCP +A CCSDK+HCCP C C Sbjct: 50 TKKSLELTETQDFGSVKCPDGSLCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNIC 118 HSP 4 Score: 55.4546 bits (132), Expect = 4.254e-8 Identity = 33/70 (47.14%), Postives = 38/70 (54.29%), Query Frame = 3 Query: 855 TKMKLKIPAISNL-SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC 1061 TK L++ + S++CPDGS C TCC SDGSY CCP NA CCSDK CCP C C Sbjct: 50 TKKSLELTETQDFGSVKCPDGS-LCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNIC 118
BLAST of Granulin b vs. TrEMBL
Match: K1PAM6 (Uncharacterized protein OS=Crassostrea gigas OX=29159 GN=CGI_10005248 PE=4 SV=1) HSP 1 Score: 342.428 bits (877), Expect = 2.109e-103 Identity = 183/438 (41.78%), Postives = 258/438 (58.90%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNP----VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI----KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 G + CCP AVCC+D +HCCP+NT+C +++G C E++ + + +VVCPD QS+C G TCC +A G+Y CCP AVCCSD +HCCP+ T C++ +G C+ V+ M + SV+CPD Q +C DG TCC +A G + CCP AVCCSD +HCCP+NT C + G C E++ +K + + + ++ CPDG S CK+G TCC L+ G+YGCCP AVCCSD CCP+ T C++S+G C+ + + ++ P V+CP +++C DGQTCCKL +G +GCCP A CCSD HCCP++T C +++G C +A++L + K+ + ++ CP+G S C TCC A Y CCP P AVCCSD HCCP NT C +++ C + L P Sbjct: 85 GQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCMRGTGEMLDWFEKEPALVRSENVVCPDGQSECKSGQTCCKLASGNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPENTKCEVSQGKCMRGTGEMLDWLKKEPAMLRSKNVVCPDGQSECKSGQTCCKLASGNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGS---TYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASG-QWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKC-IRADSLSMDWFEKLPALRTRNVVCPDGQSQCKDGQTCCKLATGQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKCKRGDELSMDWFAKLP 517 HSP 2 Score: 342.043 bits (876), Expect = 2.768e-103 Identity = 193/460 (41.96%), Postives = 263/460 (57.17%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----------NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC----------------DHQAEALEIKISPILV----ESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 G+Y CCP AVCCSD +HCCP+ T C+++ G C+ V+ + + SV+CPD Q +C DG TCC +A G + CCP AVCCSD +HCCP++T C + G C + + K+PA +VVCPD QSQC DG TCC +A G Y CCP AVCCSD +HCCP+NT C++ +G C + E+ K+PA+ + ++ CPDG S CKT TCC L+ G+YGCCP AVCCSD CCP+NT C++S+G C T+ L++ F+ P+ + V+CP +C DGQTCC L +G YGCCP A CCSD +HCCPQ T C+I + C Q + E +L+ E+++CP+G S C TCC +A +Y CCP P AVCCSD HCCP T+C +++ C++ ++ P Sbjct: 316 GNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKC-IRADSLSMDWFEKLPALRTRNVVCPDGQSQCKDGQTCCKLATGQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKC-KRGDELSMDWFAKLPALRSKNVVCPDGQSECKTSQTCCKLASGNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKC---TRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASG-KYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKLPTENVECPDGQSECKTGQTCCKTAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQP 769 HSP 3 Score: 333.954 bits (855), Expect = 3.500e-100 Identity = 195/472 (41.31%), Postives = 261/472 (55.30%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC---DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---DSKLKEVVTKMKLKIPAISN---LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK---------------------TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD----HQAEALEIKISPILVESIKCPNGS-LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFV 1577 G + CCP AVCCSD +HCCP++T+C +++G C DS+ + K+ PA +VVCPD QSQC DG TCC +A G Y CCP AVCCSD +HCCP+NT C++ +G C + E+ K+PA +VVCPD QS+C TCC +A G+Y CCP AVCCSD +HCCP+NT C++ +G C D + + KM L + + S+ CPDG+S C+ G TCCLL+ G YGCCP +AVCCSD + CCPQ T C++ C K P LL+K P V CP + +C GQTCCK AG+ YGCCP A CCSD HCCP+ T C+++ G C+ + + ++ + + + S+ CP+G C TCC A+ + CCP P AVCC+D HCCP NT C ++ C + L P V Sbjct: 393 GQWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKCIRADSLSMDWFEKL----PALRTRNVVCPDGQSQCKDGQTCCKLATGQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKC-KRGDELSMDWFAKLPALRSKNVVCPDGQSECKTSQTCCKLASGNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKCTRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASGKYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKL----PTENVECPDGQSECKTGQTCCKTAAGN-YGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCTRGTGLVLDWFEKLPALKRPGLV 854 HSP 4 Score: 316.235 bits (809), Expect = 1.347e-93 Identity = 173/428 (40.42%), Postives = 240/428 (56.07%), Query Frame = 3 Query: 303 AVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISPILVESIKCPNGS-LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 AVCCSD +HCCP+ T C+++ G C V+ + + SV+CPD Q +C DG TCC +A G + CCP AVCC+D +HCCP+NT C + G C E++ + + +VVCPD QS+C G TCC +A G+Y CCP AVCCSD +HCCP+ T C++ +G C+ V+ M + + S+ CPDG CK G TCC L+ G +GCCP AVCCSD CCP+NT C +S G C T + ++ + P V+CP + +C GQTCCKL +G+ YGCCP A CCSD HCCP+ T C+++ G C+ + + ++ + + + S+ CP+G C TCC A+ + CCP P AVCCSD HCCP +T C ++ C + L P Sbjct: 18 AVCCSDMKHCCPEGTTCDVSSGKCKRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCMRGTGEMLDWFEKEPALVRSENVVCPDGQSECKSGQTCCKLASGNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPENTKCEVSQGKCMRGTGE---MLDWLKKEPAMLRSKNVVCPDGQSECKSGQTCCKLASGN-YGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKCIRADSLSMDWFEKLP 441 HSP 5 Score: 308.531 bits (789), Expect = 1.224e-90 Identity = 187/447 (41.83%), Postives = 247/447 (55.26%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---DSKLKEVVTKMKLKVPA---SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----------LKEVVTKMKLK-----IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA-------EALEIKISPILVESIK------CPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 G Y CCP AVCCSD +HCCP+NT+C+++ G C E+ K+PA +VVCPD QS+C TCC +A G+Y CCP AVCCSD +HCCP+NT C++ +G C D + + KM L V + SV+CPD S+C DG TCC +A G Y CCP AVCCSD HCCPQ T C++ C K + ++ K + K + + ++ECPDG S CKTG TCC + G+YGCCP AVCCSD CCP+ T C++S+G C+ + + ++ P V+CP +++C DGQTCCKL +G +GCCP A CC+D HCCP+NT C +++G C E L P LVE IK CP+ C K TCC + + CC Y NAVCC ++CCP C Sbjct: 469 GQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKCKRG-DELSMDWFAKLPALRSKNVVCPDGQSECKTSQTCCKLASGNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKCTRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASGKYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKLPTENVECPDGQSECKTGQTCCKTAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCN---RGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASG-QWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCTRGTGLVLDWFEKLPALKRPGLVEMIKKDNTIVCPDQKTSCPDKNTCCKNKEGKFGCCAYNNAVCCKSGTYCCPKGYIC 910 HSP 6 Score: 256.144 bits (653), Expect = 2.519e-71 Identity = 150/371 (40.43%), Postives = 202/371 (54.45%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC---DSVLKEVVTKIKLKVPA---SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----------LKEVVTKMKLKVPASSIL-----SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV-------------NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCN 1274 G+Y CCP AVCCSD +HCCP+NT+C+++ G C D ++ + K+ L V + SV+CPD S+C DG TCC +A G Y CCP AVCCSD HCCPQ T C++ C K + ++ K + K +L +V CPD QS+C G TCC A G+Y CCP AVCCSD +HCCP+ T C++ +G C+ V+ M + + S+ CPDG CK G TCC L+ G +GCCP AVCC+D CCP+NT C +S G C T+ L++ F+ P N ++CP K C D TCCK G +GCC Y+ A CC +CCP+ +C+ Sbjct: 545 GNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKCTRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASGKYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKLPTENVECPDGQSECKTGQTCCKTAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKC---TRGTGLVLDWFEKLPALKRPGLVEMIKKDNTIVCPDQKTSCPDKNTCCKNKEG-KFGCCAYNNAVCCKSGTYCCPKGYICD 911 HSP 7 Score: 144.821 bits (364), Expect = 1.003e-32 Identity = 93/285 (32.63%), Postives = 131/285 (45.96%), Query Frame = 3 Query: 870 KIPAI---SNLSIECPDGSS---------------------------------------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISPILVESIKCPNGS-LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 K PA+ N+++ C D CK G TCC L+ G +GCCP AVCC+D CCP+NT C +S G C T + ++ F+ P V+CP + +C GQTCCKL +G+ YGCCP A CCSD HCCP+ T C+++ G C+ + + ++ + + + S+ CP+G C TCC A+ + CCP P AVCCSD HCCP NT C ++ C + + P Sbjct: 7 KEPALVRSENVAVCCSDMKHCCPEGTTCDVSSGKCKRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCMRGTGE---MLDWFEKEPALVRSENVVCPDGQSECKSGQTCCKLASGN-YGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPENTKCEVSQGKCMRGTGEMLDWLKKEP 287 HSP 8 Score: 140.969 bits (354), Expect = 1.903e-31 Identity = 78/194 (40.21%), Postives = 110/194 (56.70%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKVPASSIL-----SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCN 812 T G+Y CCP AVCCSD +HCCP+ T C+++ G C+ V+ + + SV+CPD Q +C DG TCC +A G + CCP AVCC+D +HCCP+NT C + G C V+ + LK P + ++VCPDQ + C D +TCC G + CC Y++AVCC +CCP+ +C+ Sbjct: 718 TAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCTRGTGLVLDWFEKLPALKRPGLVEMIKKDNTIVCPDQKTSCPDKNTCCKNKEGKFGCCAYNNAVCCKSGTYCCPKGYICD 911
BLAST of Granulin b vs. TrEMBL
Match: A0A2G8L0S4 (Putative fibrillin-1 isoform X4 (Fragment) OS=Stichopus japonicus OX=307972 GN=BSL78_09258 PE=4 SV=1) HSP 1 Score: 323.939 bits (829), Expect = 5.248e-100 Identity = 188/432 (43.52%), Postives = 254/432 (58.80%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPN--------AVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 + G Y CCP +AVCCSD HCCP C+ ++GTC S E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+ + +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + + V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C++++GTC +E + K V ++ CP G S C TCC ++ Y CCP PN AVCCSDH HCCPN +C ++ +C + Sbjct: 165 ILATGRYGCCPLRNAVCCSDHLHCCPNGYTCDASQGTC-SQGSEIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIMAWFE-KTEATPVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDISGGTCSQGSEIMNWFEKT-EATTLGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMNWFEKTEATTVGTVTCPGGQSECPDGSTCCLLSSGQYGCCPLPNCKILLILQAVCCSDHLHCCPNGYTCDVSQGTCSQG 588 HSP 2 Score: 308.531 bits (789), Expect = 6.021e-94 Identity = 189/445 (42.47%), Postives = 248/445 (55.73%), Query Frame = 3 Query: 270 DGSYSCCP---YSSAVCCSDK--------------QHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 DG Y CCP Y+ CS+ HCCP+ C+ ++ C V K A + SV+CPD+ S+C DGSTCC +A G Y CCP +AVCCSD HCCP C+ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + V V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C+I+ GTC +E + K + ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + I+ F Sbjct: 76 DGKYGCCPCPKYTCTALCSEDICSSSLFVKAECCDTHCCPEGFSCDGDQ--CSKEEGNVFVAGVSKTEAVIVESVMCPDRRSECPDGSTCCILATGRYGCCPLRNAVCCSDHLHCCPNGYTCDASQGTC-SQGSEIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIMAWFE-KTEATPVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDISGGTCSQGSEIMNWFEKTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMNWF 512 HSP 3 Score: 291.197 bits (744), Expect = 2.212e-87 Identity = 182/433 (42.03%), Postives = 237/433 (54.73%), Query Frame = 3 Query: 303 AVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCP---YSSAVCCSD--------------KRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 AVCCSD +HCCP C++++GTC S E + + +V +V C + C DG+TCC A G Y CCP Y+ CS+ HCCP+ C+ D C + V K A + SV+CPD +S+C DGSTCC +A G Y CCP +AVCCSD HCCP C+ GTC S+ E++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + PV V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C+++ GTC +E + K V ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + I+ F Sbjct: 16 AVCCSDGEHCCPSGYTCDVSEGTCSSE-SEKLPWFEKEVAK----NVHCGGKYYCKDGNTCCPQADGKYGCCPCPKYTCTALCSEDICSSSLFVKAECCDTHCCPEGFSCDGDQ--CSKEEGNVFVAGVSKTEAVIVESVMCPDRRSECPDGSTCCILATGRYGCCPLRNAVCCSDHLHCCPNGYTCDASQGTC-SQGSEIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMAWFEKT-EATPVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDISGGTCSQGSEIMNWF 437
BLAST of Granulin b vs. TrEMBL
Match: A0A2B4SIQ6 (Granulin OS=Stylophora pistillata OX=50429 GN=GRN PE=4 SV=1) HSP 1 Score: 333.954 bits (855), Expect = 6.825e-99 Identity = 195/437 (44.62%), Postives = 257/437 (58.81%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKV--PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAI----SNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVES----IKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 + G Y CCP AVCCSD +HCCP C+++ GTC + KL S SVVCPD +SQC DG+TCC ++ G Y CCP +AVCCSD HCCP C++ AG+C S +V K+ + S +VVCPD QS+C DG+TCC ++ G Y CCPY +AVCCSD HCCP C++ AGTC + M K+PA+ + ++ CPDG S C G TCC LS G YGCCP+ NAVCCSD CCP C++SAGTC ++ ++ K + + V+CPG + +C DG TCCKL +G YGCCPY A CCSD+ HCCP C+++ GTC + ++E+ K+ + ES + CP+G S C TCC + Y CCP PNAVCCSD HCCPN +C ++ +C + Sbjct: 339 SSGQYGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTCSKGTTSITFLQKLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQYGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPALMREKSASNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSI--PMVQKLPALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQESSSMPMMQKLPALIRERNASNVVCPGGQSECPDGNTCCKLSSGQ-YGCCPYPNAVCCSDREHCCPSGYTCDVSAGTCTQGSSSIEMFQKMPAMKRESAASYVVCPDGESECPDGTTCCKLSTGQYGCCPLPNAVCCSDGVHCCPNGYTCDVSAGTCTQG 772 HSP 2 Score: 327.405 bits (838), Expect = 1.877e-96 Identity = 193/448 (43.08%), Postives = 257/448 (57.37%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAE---ALEIKISPILVESIKCPNGSLCGQK-------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 + G Y CCPY +AVCCSD +HCCP C+++ GTC +S ++ K+ + + +VVCP QS+C DG+TCC ++ G Y CCPY +AVCCSD+ HCCP C++ AGTC S E+ KM S+ VVCPD +S+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ AGTC S +V K+ + + ++ CPDG S C G TCC LS G YGCCP+ NAVCCSD CCP C++SAGTC + ++ + + + V+CPG + +C DG TCC+L +G YGCCP A CCSD HCCP C+++ GTC + +L++ + V IK +G LC K TCC + +Y CCP NAVCCSDH HCCPN +C + C KN I N Sbjct: 576 SSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQESSSMPMMQKLPALIRERNASNVVCPGGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDREHCCPSGYTCDVSAGTCTQGSSSIEMFQKMPAMKRESAASYVVCPDGESECPDGTTCCKLSTGQYGCCPLPNAVCCSDGVHCCPNGYTCDVSAGTCTQGSSSIPMVQKLAALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSMPMVQRLPALKREKDASNVVCPGGQSECPDGNTCCRLSSGQ-YGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSGTYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHIKMIANV 1022 HSP 3 Score: 327.405 bits (838), Expect = 2.079e-96 Identity = 193/450 (42.89%), Postives = 258/450 (57.33%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL----SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------KISPILVES--IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544 + G Y CCPY +AVCCSD++HCCP C+++ GTC S E+ K+ S+ VVCPD +S+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ AGTC S +V K+ + + +VVCPD QS+C DG+TCC ++ G Y CCPY +AVCCSD HCCP C++ AGTC + M ++PA+ ++ CP G S C G TCC LS G YGCCP NAVCCSD CCP C++SAGTC + + + L V+ V+CP KYQC +G TCC++P+G +YGCCP A CCSD IHCCP C++ G C AE +++ S + E IKCP+G C TCC ++ + CCP P+AVCC DH HCCP+ C L + C ++ P++ Sbjct: 655 SSGQYGCCPYPNAVCCSDREHCCPSGYTCDVSAGTCTQGSSSIEMFQKMPAMKRESAASYVVCPDGESECPDGTTCCKLSTGQYGCCPLPNAVCCSDGVHCCPNGYTCDVSAGTCTQGSSSIPMVQKLAALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSM--PMVQRLPALKREKDASNVVCPGGQSECPDGNTCCRLSSGQYGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSG-TYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHIKMIANVPSSRSSVDTEQKYIKCPDGCSCLDYETCCVLSDGRFGCCPLPHAVCCEDHEHCCPSGYRCDLAAEMCVTGN-VRLPMLQ 1100 HSP 4 Score: 325.865 bits (834), Expect = 6.744e-96 Identity = 200/455 (43.96%), Postives = 264/455 (58.02%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL-KVPA----SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPA----SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL----SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVE----SIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPII 1541 + G Y CCP AVCCSD +HCCP C+++ GTC K T I L K+PA S SVVCPD +SQC DG+TCC + G Y CCP AVCCSD +HCCP C++ AGTC + M K PA S+ ++VCPD +S+C D +TCC ++ G Y CCP AVCCSD HCCP C++ AGTC SK +T ++ K+PA+ S+ CPDG S C G TCC LS G YGCCP NAVCCSD CCP C++SAG+C + ++ K + + V+CP + +C DG TCCKL +G YGCCPY A CCSD HCCP C+++ GTC + ++ + K+ ++ E ++ CP+G S C TCC ++ Y CCPYPNAVCCSD HCCPN +C ++ +C + ++ K P + Sbjct: 181 SSGQYGCCPLPKAVCCSDGEHCCPNGYTCDISAGTCS---KGTTTLILLQKLPAVQRKSDANSVVCPDGESQCPDGNTCCKLFSGQYGCCPLPKAVCCSDGKHCCPDGYTCDVSAGTCTQGSSSIA--MFQKKPAMKRESAESNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTC-SKGTTSITFLQ-KLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQYGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPALMREKSASNVVCPDGQSECPDGNTCCKLSSGQ-YGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSIPMVQKLPALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQESSSMPMMQKLPAL 627 HSP 5 Score: 291.197 bits (744), Expect = 4.234e-83 Identity = 179/420 (42.62%), Postives = 232/420 (55.24%), Query Frame = 3 Query: 357 LNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKV--PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIE----CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVE----SIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPII 1541 +N GTC S + K K S+ ++VCPD +S+C D +TCC ++ G Y CCP AVCCSD HCCP C++ AGTC ++ KL S SVVCPD +SQC DG+TCC + G Y CCP AVCCSD +HCCP C++ AGTC + M K PA+ S E CPDG S C TCC LS G YGCCP AVCCSD CCP C++SAGTC T + L K + + N V+CP + QC DG TCCKL G YGCCP A CCSD HCCP C+++ G+C + ++ + K+ ++ E ++ CP+G S C TCC ++ Y CCPYPNAVCCSD HCCPN +C ++ +C + ++ K P + Sbjct: 132 VNAGTCTQGSSSIAMFQKKPAKKRESAASNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDISAGTCSKGTTTLILLQKLPAVQRKSDANSVVCPDGESQCPDGNTCCKLFSGQYGCCPLPKAVCCSDGKHCCPDGYTCDVSAGTCTQGSSSIA--MFQKKPAMKRESAESNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTCSKGTTSITFLQKLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQ-YGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPALMREKSASNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSIPMVQKLPAL 548 HSP 6 Score: 224.557 bits (571), Expect = 1.558e-59 Identity = 170/469 (36.25%), Postives = 229/469 (48.83%), Query Frame = 3 Query: 333 CPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYA-CCP--YS--SAVCCS--------------------DKRHCCPQNTVCNL--------------DAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL----SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVE------SIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPII 1541 C Q T CN ++ ++VL T ++ V + +VVCP QC G +CC+V G CCP YS S VC D ++ CP ++ +AGTC S + K K S+ ++VCPD +S+C D +TCC ++ G Y CCP AVCCSD HCCP C++ AGTC ++ KL PA+ S+ CPDG S C G TCC L G YGCCP AVCCSD CCP C++SAGTC + KKP++ ++ + N ++CP + +C D TCCKL +G YGCCP A CCSD HCCP C+++ GTC ++ V+ S+ CP+G S C TCC + Y CCP PNAVCCSD HCCPN +C ++ SC + ++ K P + Sbjct: 13 CSQVTFCNADELKENTVLS-AFTSNEIDV----LDAVVCPGGVRQCPSGHSCCSVPGNDEVHCCPVGYSCESGVCQETRKDNIAALFPSVGAKIVKCDNQYACPDRSIIIFMILILCLTCIIIVVNAGTCTQGSSSIAMFQKKPAKKRESAASNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDISAGTCSKGTTTLILLQKL--PAVQRKSDANSVVCPDGESQCPDGNTCCKLFSGQYGCCPLPKAVCCSDGKHCCPDGYTCDVSAGTCTQGSSSIAMFQKKPAMKRESAESN----IVCPDGESECPDDTTCCKLSSGQ-YGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTCSKGTTSITFLQKLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQYGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPAL 469 HSP 7 Score: 205.682 bits (522), Expect = 5.422e-53 Identity = 122/297 (41.08%), Postives = 167/297 (56.23%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVT-KMKLKVPASSIL----SVVCPDQS-QCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA------ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPN 1112 + G Y CCPY +AVCCSD +HCCP C+++ GTC S +V ++ +VVCP QS+C DG+TCC ++ G Y CCP +AVCCSD +HCCP C++ AGTC + + +M + A + + V+CPD+ QC +GSTCC V G+Y CCP +AVCCSD HCCP C+++ G C + + KM +P+ I+CPDG S C TCC+LSDG +GCCP +AVCC D CCP C+L+A C + + +L K P Sbjct: 813 SSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSMPMVQRLPALKREKDASNVVCPGGQSECPDGNTCCRLSSGQYGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSGTYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHI--KMIANVPSSRSSVDTEQKYIKCPDGCS-CLDYETCCVLSDGRFGCCPLPHAVCCEDHEHCCPSGYRCDLAAEMCVTGNVRLPMLQKIRSPR 1106 HSP 8 Score: 140.969 bits (354), Expect = 2.522e-31 Identity = 83/225 (36.89%), Postives = 118/225 (52.44%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVT-----KIKLKVPASSILSVVCPDQS-QCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPAS------SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS------KLKEVVTKMKLKIPAIS 887 + G Y CCP +AVCCSD +HCCP C+++ GTC + + ++ ++ V+CPD+ QC +GSTCC V G+Y CCP +AVCCSD HCCP C+++ G C + + KM VP+S + CPD C D TCC ++ G + CCP AVCC D HCCP C+L A C + L+++ + K K P ++ Sbjct: 892 SSGQYGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSGTYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHI--KMIANVPSSRSSVDTEQKYIKCPDGCSCLDYETCCVLSDGRFGCCPLPHAVCCEDHEHCCPSGYRCDLAAEMCVTGNVRLPMLQKIRSPRKQKTPRVN 1114
BLAST of Granulin b vs. TrEMBL
Match: W4Z754 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1) HSP 1 Score: 337.806 bits (865), Expect = 4.197e-98 Identity = 193/431 (44.78%), Postives = 246/431 (57.08%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 G Y CCP +AVCCSD HCCP C ++ GTC V+ K + SVVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + SVVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V+CP + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+LVE++ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + ++L + Sbjct: 324 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWY 752 HSP 2 Score: 335.109 bits (858), Expect = 3.577e-97 Identity = 192/424 (45.28%), Postives = 240/424 (56.60%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ-PNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G Y CCP +AVCCSD HCCP C ++ GTC V K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + SV+CP Q+QC DG+TCC +A G Y CCP +AVCCSD HCCP C + AGTC V+ K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC K+ P V VICPG + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+ VE++ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 863 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVKSVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVLWFEKSAATPVQVESVICPGGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 1284 HSP 3 Score: 333.569 bits (854), Expect = 1.095e-96 Identity = 189/430 (43.95%), Postives = 239/430 (55.58%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI----KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 G Y CCP +AVCCSD HCCP C ++ GTC V K + SV+CP Q+QC DG+TCC +A G Y CCP +AVCCSD HCCP C + AGTC V+ K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V+ K + S+ CP G S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC + +P+ VES+ CP G + C TCC A+ Y CCP PNAVCCSDH HCCP+ +C ++ +C + ++L + Sbjct: 940 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVKSVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVLWFEKSAATPVQVESVICPGGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVESVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWY 1368 HSP 4 Score: 333.183 bits (853), Expect = 1.576e-96 Identity = 192/427 (44.96%), Postives = 244/427 (57.14%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G Y CCP +AVCCSD HCCP C ++ GTC V K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + SV+CP Q+QC DG+TCC +A G Y CCP +AVCCSD HCCP C + AGTC V+ K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC T+ S+++ P V V+CPG + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+ VE++ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 1171 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVESVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTC---TQGESVVLWYEKSAATPVQVESVLCPGGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 1592 HSP 5 Score: 332.413 bits (851), Expect = 2.616e-96 Identity = 191/432 (44.21%), Postives = 244/432 (56.48%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSIL--SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI----KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 G Y CCP +AVCCSD HCCP C ++ GTC E V K A+ +L +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V+ K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC + +P+ V+S+ CP G + C TCC A+ Y CCP PNAVCCSDH HCCP+ +C ++ +C + ++L + Sbjct: 632 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTC--TQGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVKSVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWY 1060 HSP 6 Score: 330.872 bits (847), Expect = 8.981e-96 Identity = 190/424 (44.81%), Postives = 240/424 (56.60%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G Y CCP +AVCCSD HCCP C ++ GTC V K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + SVVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V+ K + S+ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCC L +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+ E++ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 170 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 591 HSP 7 Score: 328.946 bits (842), Expect = 3.879e-95 Identity = 188/423 (44.44%), Postives = 236/423 (55.79%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G Y CCP +AVCCSD HCCP C ++ GTC V K + SVVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCC L +G YGCCP A CCSD +HCCP C ++ GTC + + +P+ VE++ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 401 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 822 HSP 8 Score: 328.561 bits (841), Expect = 6.021e-95 Identity = 191/427 (44.73%), Postives = 250/427 (58.55%), Query Frame = 3 Query: 282 SCCPYSSAVCCSDKQHCCPQNTECNLNKGTC---DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 CC Y +AVCCSD +HCCP EC++ TC + V++ ++T + S+ +V+CPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + S+ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC T+ S+++ + P V V+CP + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+ VES+ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 98 GCCTYPNAVCCSDGRHCCPTGYECDVTSNTCIKGNDVMRMLITDL-----TSNASAVICPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTC---TRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 514 HSP 9 Score: 328.176 bits (840), Expect = 8.022e-95 Identity = 189/424 (44.58%), Postives = 240/424 (56.60%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G Y CCP +AVCCSD HCCP C ++ GTC V K +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V+ K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCC L +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+ VE++ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 555 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 976 HSP 10 Score: 325.094 bits (832), Expect = 8.032e-94 Identity = 186/424 (43.87%), Postives = 239/424 (56.37%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G Y CCP +AVCCSD HCCP C ++ GTC V K + +VVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + SV+CP Q+QC DG+TCC + G Y CCP +AVCCSD HCCP C++ AGTC V+ K + S+ CP G + C G TCC L G YGCCP NAVCCSD CCP C++SAGTC ++ P + P + V+CP + +C DG TCCKL +G YGCCP +A CCSD +HCCP C+++ GTC Q E++ + +P+ +ES+ CP+G S C TCC A+ Y CCP PNAVCCSD HCCP+ +C ++ +C + Sbjct: 1479 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVQVDSVICPGGQAQCPDGNTCCKLPSGQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVLWYEKSSATPVQVESVVCPGGQAQCPDGNTCCKLPSGQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQ-YGCCPIPSAVCCSDHLHCCPSGYTCDVSAGTCT-QGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPLPNAVCCSDGQHCCPSGYTCDVSAGTCTQG 1900 HSP 11 Score: 322.783 bits (826), Expect = 4.844e-93 Identity = 196/441 (44.44%), Postives = 241/441 (54.65%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI-----------KISPILVESIK-CPNG-SLCGQKGTCCP-SANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544 G Y CCP +AVCCSD +HCCP C+++ GTC V+ K + SVVCP Q+QC DG+TCC + G Y CCP +AVCCSD HCCP C++ AGTC V K I SVVCPD QS+C DGSTCC +A G Y CCP SAVCCSD HCCP C++ AGTC V K + S+ CPDG S C G+TCC L+ G YGCCP NAVCCSD CCP C++SAGTC ++ P + P V V+CP + +C DG TCCKL +G YGCCP A CCSD +HCCP C ++ GTC + LE K+ E + CP+ + C TCCP A+ + CCP NAVCC DH HCCP+ SC N SC K + P+++ Sbjct: 1633 GQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVLWYEKSSATPVQVESVVCPGGQAQCPDGNTCCKLPSGQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPIPSAVCCSDHLHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPLPNAVCCSDGQHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVYVESVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGSSILEWSSKSSARSNVDKLQITATEPVSICPDSKTSCPSSSTCCPLMASGEWGCCPVHNAVCCDDHIHCCPSGYSCGTN--SCQKGS-MHLPLLS 2069 HSP 12 Score: 270.011 bits (689), Expect = 8.875e-75 Identity = 158/365 (43.29%), Postives = 205/365 (56.16%), Query Frame = 3 Query: 456 QSQCNDG----STCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 ++ C DG STCC CC Y +AVCCSD RHCCP C++ + TC V +M + S+ +V+CPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC V K + ++ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCC L +G YGCCP A CCSD +HCCP C ++ GTC + + +P+ VES+ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + Sbjct: 76 ENTCKDGCATTSTCCNDLNNESGCCTYPNAVCCSDGRHCCPTGYECDVTSNTCIKGND--VMRMLITDLTSNASAVICPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 437 HSP 13 Score: 263.077 bits (671), Expect = 2.133e-72 Identity = 184/468 (39.32%), Postives = 233/468 (49.79%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKM-------KLKIPAISNLSIECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT---------------------------FQPNP--VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 G Y CCP SAVCCSD HCCP C+++ GTC V K I SVVCPD QS+C DGSTCC +A G Y CCP +AVCCSD +HCCP C++ AGTC V K + SVVCPD QS+C DG+TCC +A G Y CCP +AVCCSD HCCP C + +GTC S + E +K KL+I A +SI CPD ++C + +TCC L++ G +GCCP NAVCC D + CCP C + +C + LL K+ FQP+ VICPG K +C DG CC L GD Y CCP A E+ + + P + S CP GS TCC + + Y CCPY A+CCSD HCCP++ SC+ +T +C K+ + P + P Sbjct: 1787 GQYGCCPIPSAVCCSDHLHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPLPNAVCCSDGQHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVYVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGSSILEWSSKSSARSNVDKLQITATEPVSI-CPDSKTSCPSSSTCCPLMASGEWGCCPVHNAVCCDDHIHCCPSGYSCGTN--SCQKGSMHLPLLSKSTGLLKLTFEGQEEPKPEVKVHDNKHLLFQPDEPRTGSVICPGGKIECQDGNACCLLAGGD-YSCCPLPQAV----------------------SPHEESGDKMMCPDEISS--CPTGS------TCCQTPGNIYGCCPYQAAICCSDLIHCCPSDYSCNSSTGTCTKDDHI-MPWVGKIP 2219 HSP 14 Score: 211.46 bits (537), Expect = 8.681e-55 Identity = 131/325 (40.31%), Postives = 178/325 (54.77%), Query Frame = 3 Query: 606 SKLKEVVTKMKLKVPASSILSVVCPDQSQCNDG----STCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---DSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 + L + LKV L+ ++ C DG STCC CC Y +AVCCSD RHCCP C++ + TC + ++ ++T + A+ CPDG S C G TCC L+ G YGCCP NAVCCSD L CCP C +S+GTC ++ P + P V V+CP + +C DG TCC L +G YGCCP A CCSD +HCCP C ++ GTC Q E++ + +P+ VES+ CP+G S C TCC A+ Y CCP PNAVCCSDH HCCP+ +C +++ +C + ++L + Sbjct: 54 ASLVSLAFGGPLKVSKVEELA----KENTCKDGCATTSTCCNDLNNESGCCTYPNAVCCSDGRHCCPTGYECDVTSNTCIKGNDVMRMLITDLTSNASAVI-----CPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWY 367
BLAST of Granulin b vs. TrEMBL
Match: A0A2G8KIP6 (Putative kielin/chordin-like protein isoform X1 OS=Stichopus japonicus OX=307972 GN=BSL78_15248 PE=4 SV=1) HSP 1 Score: 333.569 bits (854), Expect = 9.205e-97 Identity = 192/431 (44.55%), Postives = 259/431 (60.09%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK--NILLKF 1532 + + G Y CCP +AVCCSD HCCP C+++ GTC S E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E+++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ S KT + V V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C++ GTC +E + K V ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + +I+ F Sbjct: 332 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMNWFE-KTKATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMSWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMSWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMSWFEKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWF 754 HSP 2 Score: 333.183 bits (853), Expect = 1.543e-96 Identity = 187/431 (43.39%), Postives = 254/431 (58.93%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 + + G Y CCP +AVCCSD HCCP C++ GTC + + K + A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ ++ + K A + +++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + V V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C+++ GTC +E + K + ++ CP G S C TCC + Y CCP PNAVCCSDH HCCPN +C ++ +C + I+ F Sbjct: 1232 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMAWFEKTETEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSAIINWFE-KTEATTLVTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSETMAWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIINWFEKTEATTLGTVTCPGGQSECPDGNTCCLLFSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWF 1656 HSP 3 Score: 332.413 bits (851), Expect = 2.350e-96 Identity = 190/431 (44.08%), Postives = 261/431 (60.56%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK--NILLKF 1532 + + G Y CCP +AVCCSD HCCP C+++ GTC S E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E+++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E+++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C+++ GTC ++ S KT + V V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C+++ GTC ++ + K V ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + +I+ F Sbjct: 407 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMNWFE-KTKATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMSWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMSWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMSWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWFEKTDATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWF 829 HSP 4 Score: 331.643 bits (849), Expect = 4.634e-96 Identity = 190/431 (44.08%), Postives = 257/431 (59.63%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 + + G Y CCP +AVCCSD HCCP C+++ GTC S E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E+V + K A + ++ CP G C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + V V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C+++ GTC +E + K + ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + I+ F Sbjct: 32 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIIAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIVAWFE-KTEATTLGAVTCPGGQVQCPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEMINWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMNWF 454 HSP 5 Score: 331.643 bits (849), Expect = 5.665e-96 Identity = 191/431 (44.32%), Postives = 256/431 (59.40%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 + + G Y CCP +AVCCSD HCCP C+++ GTC S E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E+V + K A+++ +V CP Q QC DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + + V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C+++ GTC +E + K V ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C + +C + I+ F Sbjct: 107 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIVAWFE-KTEATTLGAVTCPGGQVQCPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEMINWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKT-EATTLGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMNWFEKTKATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMSWF 529 HSP 6 Score: 328.561 bits (841), Expect = 6.186e-95 Identity = 182/424 (42.92%), Postives = 246/424 (58.02%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 + + G Y CCP +AVCCSD HCCP C++ GTC + K A+++++V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC + + K + A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C+++ GTC ++ + KT + V V CPG + +C DG TCC L +G YGCCP A CCSD +HCCP C++ GTC + + K + ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + Sbjct: 1082 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQ--GSAIINWFEKTEATTLVTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMAWFEKTETEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMAWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSAIINWFEKTEATTLVTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQG 1499 HSP 7 Score: 301.212 bits (770), Expect = 1.449e-85 Identity = 170/380 (44.74%), Postives = 229/380 (60.26%), Query Frame = 3 Query: 414 KVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532 K A+++ +V+CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT + + V CPG + QC DG TCC L +G YGCCP A CCSD +HCCP C+++ GTC +E + K V ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C ++ +C + I+ F Sbjct: 6 KTEATTLGAVICPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIIAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIVAWFEKT-EATTLGAVTCPGGQVQCPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEMINWFEKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWF 379 HSP 8 Score: 291.197 bits (744), Expect = 4.115e-82 Identity = 181/448 (40.40%), Postives = 251/448 (56.03%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT---------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL-------VESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547 + + G Y CCP +AVCCSD HCCP C+++ GTC S +++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ +++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + KT Q + VN + +T L + YGCCP A CCSD +HCCP C++ + H + E+++ P L V ++ CP G S C TCC ++ Y CCP PNAVCCSDH HCCPN +C + +C + IIN+ Sbjct: 707 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTDATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTDATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKTEATTLEQLHVQEDKVNVQM-----------ETHVVLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVLEA---HVVK--EVRLWPGLKKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSA----IINW 1128 HSP 9 Score: 287.345 bits (734), Expect = 1.030e-80 Identity = 173/431 (40.14%), Postives = 241/431 (55.92%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538 + + G Y CCP +AVCCSD HCCP C+++ GTC S E + + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A+++ +V CP QS+C DG+TCC + G Y CCP +AVCCSD HCCP C++ GTC S+ E++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCCSD L CCP C++S GTC ++ + K QP + ++ K Q G ++Y + A CCSD +HCCP C+++ GTC ++ + K + ++ CP G S C TCC ++ Y CCP PNAVCC D SHCCP+ C+ ++C + I Sbjct: 1459 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSETMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIINWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLFSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMAWFEKMKQP-LLEQLRVRRTKKQ--KGVWIIANEIFETY----WQLAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWFEKTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPVPNAVCCEDGSHCCPSGYRCNAQAQTCSRGKHFMAWI 1876 HSP 10 Score: 256.914 bits (655), Expect = 2.621e-70 Identity = 169/447 (37.81%), Postives = 228/447 (51.01%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC----DHQAEALEIKISPILVESIK---CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYY 1568 G Y CCP +AVCCSD HCCP C+++ GTC S E++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCCSD HCCP C++ GTC + + K+K P L V +++ G + + AVCCSD HCCP C++ GTC S+ +++ + K A + ++ CP G S C G TCCLLS G YGCCP NAVCC D CCP CN A TC K+PS ++ + CP K C G TCC P D + CCP S ATCC D+ HCCP+N C N C D + + KI +++K C +GS C TCC +N +++CCP P A CC D HCCP+ C + +C L K P + P N++ Sbjct: 1613 GQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMAWFEKMKQPLLEQLRV---RRTKKQKGV---WIIANEIFETYWQLAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPVPNAVCCEDGSHCCPSGYRCNAQAQTCSRGKHFMAWIKKEPSKTVQRHPEISSEMITCPDNKTTCPPGCTCC--PFKDEFSCCPTSHATCCPDQAHCCPENFECIDNSTRCRAKSDKRIQEALKKIPGKKHDALKLVQCKDGSSCPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHH 2047 HSP 11 Score: 235.343 bits (599), Expect = 5.395e-63 Identity = 167/444 (37.61%), Postives = 231/444 (52.03%), Query Frame = 3 Query: 294 YSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD------SKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS---IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSL----LIKTFQPNPVN-RVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI-KISPIL----VESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 + AVCCSD HCCP C+++ GTC S +++ + K A+++ +V CP QS+C DG+TCC ++ G Y CCP +AVCC D HCCP CN A TC + +K+ +K + P S + CPD ++ C G TCC ++CCP S A CC D+ HCCP+N C ++ C +K + + + KIP + + ++C DGSS C +TCC+ S+G++ CCP A CC DK+ CCP C + TC S TK PS+ + P+ + C K C + TCC+ +G S+GCCP A CC D HCCP C++ TC + + K P L E I CP+ C TCC +D Y CCP+ NAVCC D HCCPN +C +T SC KN P+ P Sbjct: 1765 WQLAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPVPNAVCCEDGSHCCPSGYRCNAQAQTCSRGKHFMAWIKKEPSKTVQRHPEISSEMITCPDNKTTCPPGCTCCPFKD-EFSCCPTSHATCCPDQAHCCPENFECIDNSTRCRAKSDKRIQEALKKIPGKKHDALKLVQCKDGSS-CPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHHHPSTLALNKTCRDGKSSCPEAFTCCEEKSG-SFGCCPLKDAVCCKDHQHCCPSGYKCDVVHATCQKGSSNVTWSKKLPSLPSKKSEDITCPDMYQSCPSNTTCCRITDDLYGCCPHANAVCCDDGKHCCPNGFTCDASTGSC-KNEEENIPVSKKFP 2202 HSP 12 Score: 172.555 bits (436), Expect = 1.008e-41 Identity = 106/279 (37.99%), Postives = 146/279 (52.33%), Query Frame = 3 Query: 276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA---SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-KLKEVVTKMKLKV-----PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL-KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKK 1079 +SCCP S A CC D+ HCCP+N EC N C + + + + K+P ++ V C D S C STCC + G++ACCP A CC DK HCCP C + TC S L ++ + K+ P++ L+ C D +S C + TCC GS+ CCP AVCC D +HCCP C++ TC V KL +P+ + I CPD +C + TCC ++D YGCCP +NAVCC D CCP C+ S G+C ++ + Sbjct: 1916 EFSCCPTSHATCCPDQAHCCPENFECIDNSTRCRAKSDKRIQEALKKIPGKKHDALKLVQCKDGSSCPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHHHPSTLALNKTCRDGKSSCPEAFTCCEEKSGSFGCCPLKDAVCCKDHQHCCPSGYKCDVVHATCQKGSSNVTWSKKLPSLPSKKSEDITCPDMYQSCPSNTTCCRITDDLYGCCPHANAVCCDDGKHCCPNGFTCDASTGSCKNEEEN 2194 HSP 13 Score: 126.331 bits (316), Expect = 1.749e-26 Identity = 86/245 (35.10%), Postives = 125/245 (51.02%), Query Frame = 3 Query: 162 REFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-LKEVVTKIKLKV-----PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL-KVPASSILSVVCPDQSQ-CNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL 869 +E +K I K+V C D S C S+CC+ ++G+++CCP A CC DK HCCP +C TC S L ++ + K+ P++ L+ C D +S C + TCC GS+ CCP AVCC D +HCCP C++ TC V KL +P+ + CPD Q C +TCC + Y CCP+++AVCC D +HCCP C+ G+C ++ + + K Sbjct: 1957 QEALKKIPGKKHDALKLVQCKDGSSCPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHHHPSTLALNKTCRDGKSSCPEAFTCCEEKSGSFGCCPLKDAVCCKDHQHCCPSGYKCDVVHATCQKGSSNVTWSKKLPSLPSKKSEDITCPDMYQSCPSNTTCCRITDDLYGCCPHANAVCCDDGKHCCPNGFTCDASTGSCKNEEENIPVSKKF 2201
BLAST of Granulin b vs. Ensembl Cavefish
Match: grnb (granulins-like [Source:NCBI gene;Acc:103046308]) HSP 1 Score: 277.33 bits (708), Expect = 6.401e-84 Identity = 182/469 (38.81%), Postives = 239/469 (50.96%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKIPA-ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-----YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 T G Y CCP +A CCSD HCC + T C+L C + + V ++ ++ P S +VVCPDQ S+C D +TCC + GS+ CCP +AVCC DK HCCPQ T C+L C S + V ++ K PA V CPD+ S C D +TCC + GSY CCP AVCCSD HCCPQ T C+L C S L+ V T + + ++ S+ C + S C++G+TCC DG + CCP AVCC D + CCPQ TVC S TC + +L+ + +NRV P + C G TCCK+ +G ++GCCP A CC D +HCCP+NTVCN+ GTCD ++S V +C S C TCC + +++CCP P AVCC DH HCCP C + +SCD L P Sbjct: 35 TPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQP-SLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPC-NESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARS--TCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESG-TWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQP 497 HSP 2 Score: 264.233 bits (674), Expect = 5.396e-79 Identity = 186/474 (39.24%), Postives = 234/474 (49.37%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKVPAS-SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK--IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS--LLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ--AEALEIKISPIL---------------------VES-IKCPNGSLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 DGS+ CCP +AVCC DK HCCPQ T C+L C S + V ++ K PA V CPD+ S C D +TCC + GSY CCP AVCCSD HCCPQ T C+L C S L+ V T + V ++ SV C + C GSTCC G +ACCP AVCC D HCCPQ TVC + L +V ++ K I + + E D ++TC GATCC + G++GCCP AVCC D L CCP+NTVCN++AGTCDS + L + + P + P A QC + G TCC+ +G ++ CCP A CC D HCCPQ C+I +CDH L K P L VES KC + C + TCC + + CCP P AVCC D HCCPN+ +C +C K L Sbjct: 115 DGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSL--PPANDQCDETSACPTGTTCCRQKSG-AWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTCLKGHL 584 HSP 3 Score: 247.284 bits (630), Expect = 9.329e-73 Identity = 159/414 (38.41%), Postives = 211/414 (50.97%), Query Frame = 3 Query: 438 SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSI-LSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-----------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--------TKKPSLLIK-TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE-----SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFHP 1553 +++CPD C+DG+TCC G Y CCP +A CCSD HCC + T+C+L+ C +K + M++ + S+ +VVCPDQ S+C D +TCC + GS+ CCP +AVCC DK HCCPQ T C+L C S + V ++ K PA ++CPD S C TCC L +GSYGCCP AVCCSD + CCPQ T C+L+ C S P + +K T + P N + C G TCCK GD + CCP A CC D IHCCPQ TVC + TC A+ L ++ P + + KC + C + TCC + ++ CCP P AVCC DH HCCP NT C++ +CD L P + P Sbjct: 17 ALICPDGGMCDDGNTCCQTPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQPSLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESV------ACESGSTCCKTKDGD-WACCPLPEAVCCEDHIHCCPQGTVC--ARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTP 420 HSP 4 Score: 240.35 bits (612), Expect = 4.226e-70 Identity = 157/468 (33.55%), Postives = 224/468 (47.86%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KVPASSI--LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP--------------------DGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ------------PNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 T DG ++CCP AVCC D HCCPQ T C + + L +V ++ K + + + C + C G+TCC + G++ CCP AVCC D HCCP+NTVCN+ AGTCDS ++ + K PA+S+ + C + S C G+TCC G++ACCP AVCC D HCCPQ C++ +CD + K K PA+ +++ + D ++C TCC + +GCCP AVCC D CCP + C+ + TC K L I F+ + V V C + +C G TCC+L G +GCCP+ A CC D +HCCP C++ GTC + + ++ + E + C S C + TCC ++ ++CCP+ AVCC D HCCP C K C + L + Sbjct: 285 TKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFK-KQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTC----LKGHLEIPWFKKQEAKVTQGSEVAHGVADVQC-DSTARCPTGSTCCRLTTG-QWGCCPHVQAVCCDDHVHCCPAGYTCDLQAGTCLRTSTLHTVALTLVHTHTKEQVMCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDPKAKGCARATSLTW 745
BLAST of Granulin b vs. Ensembl Cavefish
Match: grnb (granulins-like [Source:NCBI gene;Acc:103046308]) HSP 1 Score: 277.33 bits (708), Expect = 6.401e-84 Identity = 182/469 (38.81%), Postives = 239/469 (50.96%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKIPA-ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-----YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 T G Y CCP +A CCSD HCC + T C+L C + + V ++ ++ P S +VVCPDQ S+C D +TCC + GS+ CCP +AVCC DK HCCPQ T C+L C S + V ++ K PA V CPD+ S C D +TCC + GSY CCP AVCCSD HCCPQ T C+L C S L+ V T + + ++ S+ C + S C++G+TCC DG + CCP AVCC D + CCPQ TVC S TC + +L+ + +NRV P + C G TCCK+ +G ++GCCP A CC D +HCCP+NTVCN+ GTCD ++S V +C S C TCC + +++CCP P AVCC DH HCCP C + +SCD L P Sbjct: 35 TPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQP-SLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPC-NESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARS--TCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESG-TWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQP 497 HSP 2 Score: 264.233 bits (674), Expect = 5.396e-79 Identity = 186/474 (39.24%), Postives = 234/474 (49.37%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKVPAS-SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK--IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS--LLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ--AEALEIKISPIL---------------------VES-IKCPNGSLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 DGS+ CCP +AVCC DK HCCPQ T C+L C S + V ++ K PA V CPD+ S C D +TCC + GSY CCP AVCCSD HCCPQ T C+L C S L+ V T + V ++ SV C + C GSTCC G +ACCP AVCC D HCCPQ TVC + L +V ++ K I + + E D ++TC GATCC + G++GCCP AVCC D L CCP+NTVCN++AGTCDS + L + + P + P A QC + G TCC+ +G ++ CCP A CC D HCCPQ C+I +CDH L K P L VES KC + C + TCC + + CCP P AVCC D HCCPN+ +C +C K L Sbjct: 115 DGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSL--PPANDQCDETSACPTGTTCCRQKSG-AWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTCLKGHL 584 HSP 3 Score: 247.284 bits (630), Expect = 9.329e-73 Identity = 159/414 (38.41%), Postives = 211/414 (50.97%), Query Frame = 3 Query: 438 SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSI-LSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-----------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--------TKKPSLLIK-TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE-----SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFHP 1553 +++CPD C+DG+TCC G Y CCP +A CCSD HCC + T+C+L+ C +K + M++ + S+ +VVCPDQ S+C D +TCC + GS+ CCP +AVCC DK HCCPQ T C+L C S + V ++ K PA ++CPD S C TCC L +GSYGCCP AVCCSD + CCPQ T C+L+ C S P + +K T + P N + C G TCCK GD + CCP A CC D IHCCPQ TVC + TC A+ L ++ P + + KC + C + TCC + ++ CCP P AVCC DH HCCP NT C++ +CD L P + P Sbjct: 17 ALICPDGGMCDDGNTCCQTPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQPSLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESV------ACESGSTCCKTKDGD-WACCPLPEAVCCEDHIHCCPQGTVC--ARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTP 420 HSP 4 Score: 240.35 bits (612), Expect = 4.226e-70 Identity = 157/468 (33.55%), Postives = 224/468 (47.86%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KVPASSI--LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP--------------------DGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ------------PNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 T DG ++CCP AVCC D HCCPQ T C + + L +V ++ K + + + C + C G+TCC + G++ CCP AVCC D HCCP+NTVCN+ AGTCDS ++ + K PA+S+ + C + S C G+TCC G++ACCP AVCC D HCCPQ C++ +CD + K K PA+ +++ + D ++C TCC + +GCCP AVCC D CCP + C+ + TC K L I F+ + V V C + +C G TCC+L G +GCCP+ A CC D +HCCP C++ GTC + + ++ + E + C S C + TCC ++ ++CCP+ AVCC D HCCP C K C + L + Sbjct: 285 TKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFK-KQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTC----LKGHLEIPWFKKQEAKVTQGSEVAHGVADVQC-DSTARCPTGSTCCRLTTG-QWGCCPHVQAVCCDDHVHCCPAGYTCDLQAGTCLRTSTLHTVALTLVHTHTKEQVMCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDPKAKGCARATSLTW 745
BLAST of Granulin b vs. Ensembl Cavefish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 264.233 bits (674), Expect = 5.242e-79 Identity = 178/497 (35.81%), Postives = 233/497 (46.88%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC-----------------------------------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTK--MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---LEIKIS-PI----------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 TTDG + CCP AVCC+DK HCCP+N+ C++N C + LK T S++ +V C D C DG+TCC G ++CCP AVCC D HCCP CNL AG C+ LK+V ++ + K+P + + +V C D + C D +TCC + G + CCP AVCC D HCCP CNL AGTC+ V KL K+P ++ C D ++ C TCC S+G + CCP AVCC D CCP CN++AGTC+ + K PS I + V P A + C D TCCK G + CCP A CC D +HCCP CN+ TCD + + LE K S PI ++ C + C TCC N +SCCP+P VCC D HCCP++ +C+L T +CDKN Sbjct: 188 TTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCND-TAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKG-GWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKN 682 HSP 2 Score: 228.024 bits (580), Expect = 1.404e-65 Identity = 156/482 (32.37%), Postives = 217/482 (45.02%), Query Frame = 3 Query: 279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------------------DSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTK--MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 Y CCP + + C+D+ HCCP + EC+ + +C +K P V+CPD S+C +TCC G + CCP AVCC+DK HCCP+N+VC++++ C + LK T S++ +V C D C DG+TCC G ++CCP AVCC D HCCP CNL AG C+ LK+V ++ + K+P ++ C D ++ C TCC S+G + CCP AVCC D + CCP CNL+AGTC+ + +K P+ P K C D TCCK G+ + CCP A CC D HCCP CN+ GTC+ + ++ K+ + + C C + TCC + +SCCP P AVCC D HCCP+ C+L +CD Sbjct: 132 YGCCPVTQGIVCADRNHCCPNDHECSADSISC----------VKKAEP------VMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCND-TAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGS-VPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCD 594 HSP 3 Score: 224.557 bits (571), Expect = 2.243e-64 Identity = 156/447 (34.90%), Postives = 211/447 (47.20%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTK--IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKS 1505 +G +SCCP AVCC D HCCP +CNL G C+ LK+V ++ + K+P + + +V C D + C D +TCC + G + CCP AVCC D HCCP CNL AGTC+ V KL K+P + + +V C D + C D +TCC + G + CCP AVCC D +HCCP CN+ AGTC+ V K+ K+P + + C + + C+ +TCC G + CCP AVCC D L CCP CNL+A TCD + KKPS I K V C + + C TCCK + CCP+ CC D+IHCCP + CN+ TCD ++ + +K +K AN+ V C DH H CP+ T+C K+ Sbjct: 307 EGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPC-NATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHF-CPASSTCCK-DVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVP------MAGPVKASGPPPPEKKKPKENKANE---------PVKCDDH-HSCPDQTTCCFMNKT 734 HSP 4 Score: 205.682 bits (522), Expect = 1.544e-57 Identity = 148/495 (29.90%), Postives = 211/495 (42.63%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS---------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE-----------------------VVTKMKLKIPAISN------------------LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 V + G Y+CCP+ CC D HCCP C + C + + + PA + L+ ++CPD S C +C + Y CCP + + C+D+ HCCP + C+ D+ +C K + V+CPD S+C +TCC G + CCP AVCC+DK HCCP+N+VC++++ C S + V K+ K P S ++ C D + C G TCC +G + CCP AVCC D L CCP CNL AG C+ + L K P+ P K C D TCCK G+ + CCP A CC D IHCCP CN+ GTC+ + ++ K+ V ++ C + + C + TCC + + CCP P AVCC D HCCP+ C++ +C+ Sbjct: 38 VLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSL--SWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLT-DKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE----------------PVMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWL-KKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCE 510 HSP 5 Score: 192.971 bits (489), Expect = 6.099e-53 Identity = 138/445 (31.01%), Postives = 200/445 (44.94%), Query Frame = 3 Query: 393 VVTKIKLKVPASSILSVV----CPDQSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------DSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF-----------------------QP-------------------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL------------EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 ++T +KL V A ++L +V CP+Q C D TCC V + G Y CCP+ CC D HCCP +C C + K + ++ +SS + ++CPD S C +C + Y CCP + + C+D+ HCCP + C+ D+ +C K + V+ CPDG S C TCC +DG +GCCP AVCC+DK+ CCP+N+VC++++ C S T K + F QP + V V C C+DG TCCK G + CCP A CC D +HCCP CN+ G C+ + ++ E K+ V ++ C + + C + TCC + + CCP P AVCC D HCCP+ C+L +C+ Sbjct: 2 LLTMLKLMV-ALALLGLVTGTQCPNQQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLTD-KYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAEPVM----------------CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEG-GWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCE 426 HSP 6 Score: 178.718 bits (452), Expect = 7.861e-48 Identity = 110/294 (37.41%), Postives = 138/294 (46.94%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT 1073 ++G + CCP AVCC D HCCP +CNL GTC+ V KL K+P + + +V C D + C D +TCC + G + CCP AVCC D +HCCP CN+ AGTC+ V K+ K+P V C C D STCC G ++CCP AVCC D HCCP CNL A TCD + K I + E D S C +TCC + + CCPF VCC D++ CCP + CNL TCD T Sbjct: 390 SEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNT 683 HSP 7 Score: 128.257 bits (321), Expect = 7.480e-31 Identity = 86/260 (33.08%), Postives = 112/260 (43.08%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS----------KLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA------------ISNLSIECPDGSSTCKTGATCCLLS 956 ++G + CCP AVCC D QHCCP +CN+ GTC+ V K+ K+P V C C D STCC G ++CCP AVCC D HCCP CNL A TCD K + + ++ +V C C STCC ++CCP+ VCC D+ HCCP + CNL TCD V +K +N ++C D S C TCC ++ Sbjct: 474 SEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVPMAGPVKASGPPPPEKKKPKENKANEPVKCDDHHS-CPDQTTCCFMN 732 HSP 8 Score: 117.472 bits (293), Expect = 3.199e-27 Identity = 87/255 (34.12%), Postives = 130/255 (50.98%), Query Frame = 3 Query: 849 VVTKMKLKIPAISNLSI----ECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPS--LLIKTFQ---PNPVNR--VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 ++T +KL + A++ L + +CP+ C TCC +LS G Y CCPF CC D L CCP +C + C + T +KP+ L K+F+ + N+ +ICP C +C KL D YGCCP + C+D+ HCCP + C+ + +C +AE P++ CP+G S C + TCCP+ + + CCP P AVCC+D HCCP N+ C +N+ C + + P+ P Sbjct: 2 LLTMLKLMV-ALALLGLVTGTQCPN-QQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPD-NSSCPPEFSCLKL--TDKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE-------PVM-----CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFP 239
BLAST of Granulin b vs. Ensembl Cavefish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 261.151 bits (666), Expect = 7.135e-78 Identity = 177/497 (35.61%), Postives = 226/497 (45.47%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC-----------------------------------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---LEIKIS-PI----------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 TTDG + CCP AVCC+DK HCCP+N+ C++N C + LK T S++ +V C D C DG+TCC G ++CCP AVCC D HCCP CNL AGTC+ V KL K+P + + +V C D + C D +TCC + G + CCP AVCC D HCCP CNL AGTC+ V K+ K+P + C D + C TCC G + CCP AVCC D CCP CN++AGTC+ + K PS I + V P A + C D TCCK G + CCP A CC D +HCCP CN+ TCD + + LE K S PI ++ C + C TCC N +SCCP+P VCC D HCCP++ +C+L T +CDKN Sbjct: 188 TTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCND-TVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKG-GWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKN 682 HSP 2 Score: 228.409 bits (581), Expect = 8.797e-66 Identity = 157/482 (32.57%), Postives = 213/482 (44.19%), Query Frame = 3 Query: 279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------------------DSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK---------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 Y CCP + + C+D+ HCCP + EC+ + +C +K P V+CPD S+C +TCC G + CCP AVCC+DK HCCP+N+VC++++ C + LK T S++ +V C D C DG+TCC G ++CCP AVCC D HCCP CNL AGTC+ V KL K+P ++ C D ++ C TCC S+G + CCP AVCC D + CCP CNL+AGTC+ + +K P+ P K C D TCCK G + CCP A CC D HCCP CN+ GTC+ + ++ K+ + + C C + TCC + +SCCP P AVCC D HCCP+ C+L +CD Sbjct: 132 YGCCPVTQGIVCADRNHCCPNDHECSADSISC----------VKKAEP------VMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCND-TAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGS-VPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKG-GWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCD 594 HSP 3 Score: 219.935 bits (559), Expect = 1.186e-62 Identity = 156/447 (34.90%), Postives = 204/447 (45.64%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKS 1505 +G +SCCP AVCC D HCCP +CNL GTC+ V KL K+P + + +V C D + C D +TCC + G + CCP AVCC D HCCP CNL AGTC+ V K+ K+P + V C D C D +TCC G + CCP AVCC D +HCCP CN+ AGTC+ V K+ K+P + + C + + C+ +TCC G + CCP AVCC D L CCP CNL+A TCD + KKPS I K V C + + C TCCK + CCP+ CC D+IHCCP + CN+ TCD ++ + +K +K AN+ V C DH H CP+ T+C K+ Sbjct: 307 EGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPC-NATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHF-CPASSTCCKD-VNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVP------MAGPVKASGPPPPEKKKPKENKANE---------PVKCDDH-HSCPDQTTCCFMNKT 734 HSP 4 Score: 203.756 bits (517), Expect = 8.091e-57 Identity = 148/495 (29.90%), Postives = 214/495 (43.23%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS---------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE-----------------------VVTKMKLKIPAISN------------------LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGS--------LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 V + G Y+CCP+ CC D HCCP C + C + + + PA + L+ ++CPD S C +C + Y CCP + + C+D+ HCCP + C+ D+ +C K + V+CPD S+C +TCC G + CCP AVCC+DK HCCP+N+VC++++ C S + V K+ K P S ++ C D + C G TCC +G + CCP AVCC D + CCP CNL+AGTC+ + +K P+ P K C D TCCK G+ + CCP A CC D IHCCP CN+ GTC+ + ++ ++ PI + + GS C + TCC + ++CCP P AVCC D HCCP+ C++ +C+ Sbjct: 38 VLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSL--SWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLT-DKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE----------------PVMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGS-VPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCE 510 HSP 5 Score: 194.512 bits (493), Expect = 2.059e-53 Identity = 139/445 (31.24%), Postives = 200/445 (44.94%), Query Frame = 3 Query: 393 VVTKIKLKVPASSILSVV----CPDQSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------DSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF-----------------------QP-------------------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 ++T +KL V A ++L +V CP+Q C D TCC V + G Y CCP+ CC D HCCP +C C + K + ++ +SS + ++CPD S C +C + Y CCP + + C+D+ HCCP + C+ D+ +C K + V+ CPDG S C TCC +DG +GCCP AVCC+DK+ CCP+N+VC++++ C S T K + F QP + V V C C+DG TCCK G + CCP A CC D IHCCP CN+ GTC+ + ++ K+ V ++ C + + C + TCC + + CCP P AVCC D HCCP+ C+L +C+ Sbjct: 2 LLTMLKLMV-ALALLGLVTGTQCPNQQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLTD-KYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAEPVM----------------CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEG-GWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCE 426 HSP 6 Score: 172.17 bits (435), Expect = 1.297e-45 Identity = 111/294 (37.76%), Postives = 139/294 (47.28%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTK-IK-LKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT 1073 ++G + CCP AVCC D HCCP +CNL GTC+ +K+V ++ IK K+P + V C D C D +TCC G + CCP AVCC D +HCCP CN+ AGTC+ V K+ K+P V C C D STCC G ++CCP AVCC D HCCP CNL A TCD + K I + E D S C +TCC + + CCPF VCC D++ CCP + CNL TCD T Sbjct: 390 SEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNT 683 HSP 7 Score: 117.087 bits (292), Expect = 3.407e-27 Identity = 87/255 (34.12%), Postives = 130/255 (50.98%), Query Frame = 3 Query: 849 VVTKMKLKIPAISNLSI----ECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPS--LLIKTFQ---PNPVNR--VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 ++T +KL + A++ L + +CP+ C TCC +LS G Y CCPF CC D L CCP +C + C + T +KP+ L K+F+ + N+ +ICP C +C KL D YGCCP + C+D+ HCCP + C+ + +C +AE P++ CP+G S C + TCCP+ + + CCP P AVCC+D HCCP N+ C +N+ C + + P+ P Sbjct: 2 LLTMLKLMV-ALALLGLVTGTQCPN-QQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPD-NSSCPPEFSCLKL--TDKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE-------PVM-----CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFP 239
BLAST of Granulin b vs. Ensembl Cavefish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434]) HSP 1 Score: 259.996 bits (663), Expect = 1.793e-77 Identity = 177/497 (35.61%), Postives = 229/497 (46.08%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC-----------------------------------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTK--MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---LEIKIS-PI----------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 TTDG + CCP AVCC+DK HCCP+N+ C++N C + LK T S++ +V C D C DG+TCC G ++CCP AVCC D HCCP CNL AG C+ LK+V ++ + K+P + + +V C D + C D +TCC + G + CCP AVCC D HCCP CNL AGTC+ V KL K+P + C D + C TCC G + CCP AVCC D CCP CN++AGTC+ + K PS I + V P A + C D TCCK G + CCP A CC D +HCCP CN+ TCD + + LE K S PI ++ C + C TCC N +SCCP+P VCC D HCCP++ +C+L T +CDKN Sbjct: 188 TTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCND-TVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKG-GWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKN 682 HSP 2 Score: 219.164 bits (557), Expect = 2.556e-62 Identity = 156/447 (34.90%), Postives = 207/447 (46.31%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTK--IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKS 1505 +G +SCCP AVCC D HCCP +CNL G C+ LK+V ++ + K+P + + +V C D + C D +TCC + G + CCP AVCC D HCCP CNL AGTC+ V KL K+P + V C D C D +TCC G + CCP AVCC D +HCCP CN+ AGTC+ V K+ K+P + + C + + C+ +TCC G + CCP AVCC D L CCP CNL+A TCD + KKPS I K V C + + C TCCK + CCP+ CC D+IHCCP + CN+ TCD ++ + +K +K AN+ V C DH H CP+ T+C K+ Sbjct: 307 EGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPC-NATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHF-CPASSTCCK-DVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVP------MAGPVKASGPPPPEKKKPKENKANE---------PVKCDDH-HSCPDQTTCCFMNKT 734 HSP 3 Score: 202.601 bits (514), Expect = 2.470e-56 Identity = 149/495 (30.10%), Postives = 212/495 (42.83%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS---------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE-----------------------VVTKMKLKIPAISN------------------LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGS--------LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 V + G Y+CCP+ CC D HCCP C + C + + + PA + L+ ++CPD S C +C + Y CCP + + C+D+ HCCP + C+ D+ +C K + V+CPD S+C +TCC G + CCP AVCC+DK HCCP+N+VC++++ C S + V K+ K P S ++ C D + C G TCC +G + CCP AVCC D L CCP CNL AG C+ + L K P+ P K C D TCCK G+ + CCP A CC D IHCCP CN+ GTC+ + ++ ++ PI + + GS C + TCC + ++CCP P AVCC D HCCP+ C++ +C+ Sbjct: 38 VLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSL--SWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLT-DKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE----------------PVMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWL-KKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCE 510 HSP 4 Score: 192.586 bits (488), Expect = 7.961e-53 Identity = 138/445 (31.01%), Postives = 200/445 (44.94%), Query Frame = 3 Query: 393 VVTKIKLKVPASSILSVV----CPDQSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------DSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF-----------------------QP-------------------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL------------EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511 ++T +KL V A ++L +V CP+Q C D TCC V + G Y CCP+ CC D HCCP +C C + K + ++ +SS + ++CPD S C +C + Y CCP + + C+D+ HCCP + C+ D+ +C K + V+ CPDG S C TCC +DG +GCCP AVCC+DK+ CCP+N+VC++++ C S T K + F QP + V V C C+DG TCCK G + CCP A CC D +HCCP CN+ G C+ + ++ E K+ V ++ C + + C + TCC + + CCP P AVCC D HCCP+ C+L +C+ Sbjct: 2 LLTMLKLMV-ALALLGLVTGTQCPNQQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLTD-KYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAEPVM----------------CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEG-GWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCE 426 HSP 5 Score: 173.326 bits (438), Expect = 5.885e-46 Identity = 110/294 (37.41%), Postives = 134/294 (45.58%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT 1073 ++G + CCP AVCC D HCCP +CNL GTC+ V KL K+P + V C D C D +TCC G + CCP AVCC D +HCCP CN+ AGTC+ V K+ K+P V C C D STCC G ++CCP AVCC D HCCP CNL A TCD + K I + E D S C +TCC + + CCPF VCC D++ CCP + CNL TCD T Sbjct: 390 SEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNT 683 HSP 6 Score: 117.087 bits (292), Expect = 3.628e-27 Identity = 87/255 (34.12%), Postives = 130/255 (50.98%), Query Frame = 3 Query: 849 VVTKMKLKIPAISNLSI----ECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPS--LLIKTFQ---PNPVNR--VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 ++T +KL + A++ L + +CP+ C TCC +LS G Y CCPF CC D L CCP +C + C + T +KP+ L K+F+ + N+ +ICP C +C KL D YGCCP + C+D+ HCCP + C+ + +C +AE P++ CP+G S C + TCCP+ + + CCP P AVCC+D HCCP N+ C +N+ C + + P+ P Sbjct: 2 LLTMLKLMV-ALALLGLVTGTQCPN-QQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPD-NSSCPPEFSCLKL--TDKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE-------PVM-----CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFP 239
BLAST of Granulin b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009302.1 (pep scaffold:Pmarinus_7.0:GL483232:1183:11161:1 gene:ENSPMAG00000008413.1 transcript:ENSPMAT00000009302.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 314.309 bits (804), Expect = 1.296e-98 Identity = 192/444 (43.24%), Postives = 233/444 (52.48%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKI-SPILV-----ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 T G ++CCP AVCC D +HCCPQ T CNL TCD + K PA + V+C DQS C DG+TCC GG +ACCP AVCC D HCCPQ T CNL A TCD + K PA + V+C DQS C DG+TCC + G + CCP AVCC D +HCCP+ T CNL CD + K L++ N+ I D +C G TCC L G +GCCP AVCC D CCPQ T CNL A TCD TK P+L + N VIC ++ C DG TCCK+P+GD +GCCP A CC D HCCPQ T CN+ TCD A +L +P L +KC + C + TCC + + CCP AVCC DH HCCP T+C++ SCD+ L Sbjct: 229 TPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQ--GTLSLPWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSL--PWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSLPWSTKTPALRVAGEPNVVIC--DDQFSCPDGNTCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVA----GEPNVVIC-DDQFSCPDGDTCCKMPSGD-WGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGALSLPWSTKTPALRVAGEPNDVKCDDQVSCPDQTTCCKTGTGDWGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSCDQGQL 660 HSP 2 Score: 309.686 bits (792), Expect = 8.411e-97 Identity = 191/451 (42.35%), Postives = 232/451 (51.44%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 + G + CCP AVCC DK+HCCP+ T CN+ TC+ + K PA + V C D C DG+TCC GG +ACCP AVCC D HCCPQ T CNL A TCD + K PA + V+C DQS C DG+TCC GG +ACCP AVCC D HCCPQ T CNL A TCD + K L++ N+ I D S+C G TCC + G +GCCP AVCC D CCP+ T CNL CD TK P+L + N VIC ++ C DG TCCKLP+GD +GCCP A CC D HCCPQ T CN+ TCD + AL + P +V + CP+G TCC + + CCP AVCC DH HCCP T+C+L ++CDK L Sbjct: 150 ILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALSL--PWSTKTPALRMTGEPNDVQCDDLVGCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSL--PWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVIC--DDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSLPWSTKTPALRVA----GEPNVVIC-DDQFSCPDGNTCCKLPSGD-WGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVICDDQFSCPDGD------TCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGAL 582 HSP 3 Score: 286.96 bits (733), Expect = 3.714e-88 Identity = 183/454 (40.31%), Postives = 227/454 (50.00%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPV---NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL--------EIKISPILVES-------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 T G ++CCP AVCC D +HCCPQ T CNL TCD + K PA + V+C DQS C DG+TCC + G + CCP AVCC D +HCCP+ T CNL CD + K PA + V+C DQ C DG+TCC + G + CCP AVCC D HCCPQ T CNL A TCD + K L++ N+ I D +C G TCC + G +GCCP AVCC D CCPQ T CNL A TCD TK P+L + +PN V ++V CP D TCCK GD +GCCP A CC D HCCP+ T CN+ G+CD +L +++ +L S ++C + C TCC + CCP P A CCSD HCCP+ +C L SC K Sbjct: 307 TPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQ--GTLSLPWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSL--PWSTKTPALRVAGEPNVVICDDQFSCPDGNTCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVIC--DDQFSCPDGDTCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGALSLPWSTKTPALRV-AGEPNDVKCDDQVSCP-------DQTTCCKTGTGD-WGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSCDQGQLSLPWSSKTPARTRLTALLPASAAARGGSVRCDSAYACPDGTTCCQLPQGQWGCCPLPLATCCSDFVHCCPSGYTCDLAQASCIKK 745 HSP 4 Score: 283.878 bits (725), Expect = 5.115e-87 Identity = 182/444 (40.99%), Postives = 228/444 (51.35%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 G Y CC AVCCSD HCCP+NT C+L G C V ++ K P+ S V C + C+D +TCC + G + CCP AVCC DK HCCP+ T+CN+ + TC+ + K PA + V C D C DG+TCC GG +ACCP AVCC D HCCPQ T CNL A TCD + K L++ N+ I D S+C G TCC G + CCP AVCC D CCPQ T CNL A TCD TK P+L + N VIC + C DG TCCK+P+GD +GCCP A CC D HCCP+ T CN+ CD + AL + P +V + CP+G+ TCC + + CCP AVCC DH HCCP T+C+L ++CD+ L Sbjct: 79 GQYGCCSLEDAVCCSDYLHCCPKNTMCDLKLGKC--VHGKLSIPWVSKYPSKQAASDVQCDAFTSCSDQNTCCILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALSL--PWSTKTPALRMTGEPNDVQCDDLVGCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVIC--DDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVA----GEPNVVIC-DDQSSCPDGNTCCKMPSGD-WGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSLPWSTKTPALRVAGEPNVVICDDQFSCPDGN------TCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTL 504 HSP 5 Score: 263.848 bits (673), Expect = 1.664e-79 Identity = 177/440 (40.23%), Postives = 219/440 (49.77%), Query Frame = 3 Query: 300 SAVCCSDKQHCCPQNTECNLNKGTCDS--VLKEVVTKIKLKVPASSILSVV---------CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-DSKLK-EVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523 AVCCSD HCCP T C+L G C + + K P + + CPD + C D +TCC +A G Y CC AVCCSD HCCP+NT+C+L G C KL V+K K AS V C + C+D +TCC + G + CCP AVCC DK HCCP+ T+CN+ + TC+ + K L++ N ++C D C G TCC G + CCP AVCC D CCPQ T CNL A TCD TK P+L + N VIC + C DG TCCK P GD + CCP A CC D HCCPQ T CN+ TCD + AL + P +V C + S C TCC + + CCP P AVCC DH HCCP T+C+L + CDK L Sbjct: 1 QAVCCSDGLHCCPSGTVCDLAHGMCQKGKISVPWLEKTPTFTPRTWRWRLARSLAVRPPQCPDGTSCGDDATCCPLASGQYGCCSLEDAVCCSDYLHCCPKNTMCDLKLGKCVHGKLSIPWVSKYPSKQAAS---DVQCDAFTSCSDQNTCCILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALSLPWSTKTPALRMTGEPN-DVQC-DDLVGCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVA----GEPNVVIC-DDQSSCPDGNTCCKTPGGD-WACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVV---ICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTL 426 HSP 6 Score: 199.904 bits (507), Expect = 5.395e-56 Identity = 123/299 (41.14%), Postives = 148/299 (49.50%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP------------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPN 1112 G + CCP AVCC D +HCCPQ T CNL TCD + K PA + V+C DQ C DG TCC + G + CCP AVCC D HCCPQ T CNL A TCD + K L+V A V C DQ C D +TCC G + CCP AVCC D HCCP+ T CN+ AG+CD ++ K PA + L+ P D + C G TCC L G +GCCP A CCSD + CCP C+L+ +C KKP L T+ P Sbjct: 466 GDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQ--GTLSLPWSTKTPALRVAGEPNVVICDDQFSCPDGDTCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGALSLPWSTKTPALRV-AGEPNDVKCDDQVSCPDQTTCCKTGTGDWGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSCDQG--QLSLPWSSKTPARTRLTALLPASAAARGGSVRCDSAYACPDGTTCCQLPQGQWGCCPLPLATCCSDFVHCCPSGYTCDLAQASC---IKKPHFL--TWAPK 754
BLAST of Granulin b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001039.1 (pep scaffold:Pmarinus_7.0:GL484091:11570:24665:-1 gene:ENSPMAG00000000936.1 transcript:ENSPMAT00000001039.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 179.104 bits (453), Expect = 1.623e-49 Identity = 141/423 (33.33%), Postives = 181/423 (42.79%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTK-IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 + G + CC A CCSD HCCP T C + + + L + K L P + V C C TCC G + CC A CCSD HCCP T C + + L + K L P L V C C TCC G + CC A CCSD HCCP T C + + L + K + + + C G C+ TCC G +GCC A CCSD + CCP +L +S P L + PV N V C G +Y C QTCC+ G +GCC ATCCSD IHCCP T C + C +EAL + S L ++ + C + TCC S + CC A CCSD HCCP+ T C + + C ++ Sbjct: 160 SRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNV-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNVVHC-GGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQY-CRRWQTCCRSRRG-MWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSGVAGSSTLSHALPYDSRVYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRS 577 HSP 2 Score: 177.948 bits (450), Expect = 4.072e-49 Identity = 144/433 (33.26%), Postives = 185/433 (42.73%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNL-NKGTC---DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKIS-PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 G + CC A CCSD HCCP T C + +G C +++ + + L P L V C C TCC G + CC A CCSD HCCP T C + C + + L +VV C C TCC G + CC A CCSD HCCP T C + + L + K + + + C G C+ TCC G +GCC A CCSD + CCP T C L +S P L + PV N V C G +Y C QTCC+ G +GCC ATCCSD IHCCP T C + G C + A + E +S P+ + C G C + TCC S + CC A CCSD HCCP+ S L + + L+ + Sbjct: 7 GMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSVLDYLSREQQDGYNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNVVHC-GGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRC-LVGQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQY-CRRWQTCCRSRCG-MWGCCNGRKATCCSDGIHCCPSMTRCLV--GQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQCVNSAALIPW 432 HSP 3 Score: 175.252 bits (443), Expect = 3.513e-48 Identity = 146/426 (34.27%), Postives = 183/426 (42.96%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKIS-PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 G + CC A CCSD HCCP T C + C + + L +VV C C TCC G + CC A CCSD HCCP T C + + L + K L P + V C C TCC G + CC A CCSD HCCP T C + + L + K L P NL + C G C+ TCC G +GCC A CCSD + CCP T C L +S P L + PV N V C G +Y C QTCC+ G +GCC ATCCSD IHCCP ++ KG C + A + E +S P+ + C G C + TCC S + CC A CCSD HCCP+ T C + + C ++ Sbjct: 86 GMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSVLDYLSREQQDGYNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNV-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNL-VHC-GGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRC-LVGQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQY-CRRWQTCCRSRRG-MWGCCNGRRATCCSDGIHCCPSGASGDL-KGQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRS 504 HSP 4 Score: 146.747 bits (369), Expect = 3.993e-38 Identity = 121/347 (34.87%), Postives = 150/347 (43.23%), Query Frame = 3 Query: 483 CCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLD-AGTC---DSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKIS-PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 CC G + CC A CCSD HCCP T C + G C + + + + L P L V C C TCC G + CC A CCSD HCCP T C + C + + L ++ G C+ TCC G +GCC A CCSD + CCP T C L +S P L + PV N V C G +Y C QTCC+ G +GCC ATCCSD IHCCP T C + G C + A + E +S P+ + C G C + TCC S + CC A CCSD HCCP+ T C Sbjct: 1 CCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSVLDYLSREQQDGYNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRC-LVGQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQY-CRRWQTCCRSRCG-MWGCCNGRRATCCSDGIHCCPSMTRCLV--GQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRC 341 HSP 5 Score: 142.124 bits (357), Expect = 1.648e-36 Identity = 115/352 (32.67%), Postives = 148/352 (42.05%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTK-IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE 1316 G + CC A CCSD HCCP T C + + + L + K L P L V C C TCC G + CC A CCSD HCCP T C + + L + K L P + V C C TCC G + CC A CCSD HCCP +L +S + + + L P NL + C G C+ TCC G +GCC A CCSD + CCP T C + C ++ L + ++ + ++ C QTCC+ G +GCC ATCCSD IHCCP T C + C +EAL Sbjct: 239 GMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNV-VHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQCVNSAALIPWLKKEAALSGPVGDNL-VHC-GGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLC---SRSSEALSGVAGSSTLSHALPYDSRVYCRRWQTCCRSRCG-MWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRSSEALS 582
BLAST of Granulin b vs. Ensembl Nematostella
Match: EDO27824 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T870]) HSP 1 Score: 137.887 bits (346), Expect = 1.649e-37 Identity = 88/227 (38.77%), Postives = 110/227 (48.46%), Query Frame = 3 Query: 423 ASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD-SKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----------LKIPAISNLSIE-CPDGSS----TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAG 1055 AS + C D S C D TCC ++ GSY CCP +AVCCSD +HCCP C++ + TCD +K + V + + + C D S CN G TCC V Y CCP SAVCC+D +HCCP CN +G C + K K P I + +I P G C+ TCC S CCP NA CCSD L CCPQ +C+ G Sbjct: 1 ASGANYITCNDGSHCYDYETCCELSTGSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHCQRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGCACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFICDDQKG 227 HSP 2 Score: 115.161 bits (287), Expect = 2.496e-29 Identity = 90/229 (39.30%), Postives = 113/229 (49.34%), Query Frame = 3 Query: 897 IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD-SKTKKPSLLIK-TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-------------EIKISPILVE-SIK-CPNGSL-----CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 I C DGS C TCC LS GSYGCCP NAVCCSD CCP C++S+ TCD +K P + T Q V + C + C+ G+TCC L YGCCP +A CC+D HCCP CN G C L + +P++++ +I+ P G C TCC S++ +CCP PNA CCSD HCCP C + K C K Sbjct: 7 ITCNDGSH-CYDYETCCELSTGSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSH-CNTGETCC-LVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHCQRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGCACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFICD-DQKGCVKQ 231 HSP 3 Score: 113.235 bits (282), Expect = 1.182e-28 Identity = 74/203 (36.45%), Postives = 93/203 (45.81%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV-VTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVC-------------PDQSQ-----CNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAG 824 GSY CCP +AVCCSD +HCCP C+++ TCD + V + + + C D S CN G TCC V Y CCP SAVCC+D +HCCP CN +G C + V M K P+ V P + C TCC + CCP +A CCSD HCCPQ +C+ G Sbjct: 27 GSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHC--QRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGCACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFICDDQKG 227 HSP 4 Score: 76.2554 bits (186), Expect = 8.976e-16 Identity = 58/195 (29.74%), Postives = 77/195 (39.49%), Query Frame = 3 Query: 984 SNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI-----KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 +N + C+D C T C LS G SYGCCP A CCSD HCCP C+I+ TCD ++ + + V IKC +GS C TCC Y CCP P+AVCC+D HCCP+ +C+ + C + + P+ HP Sbjct: 4 ANYITCNDGSHCYDYETCCELSTG----------------------------------------------SYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHCQRGRHV-LPMFQKHP 151
BLAST of Granulin b vs. Ensembl Medaka
Match: grnb (granulin precursor [Source:NCBI gene;Acc:101166910]) HSP 1 Score: 283.108 bits (723), Expect = 6.554e-86 Identity = 179/466 (38.41%), Postives = 240/466 (51.50%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA-------ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD--SKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQ-----------TCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 DGS+ CCP+ AVCC D++HCCP+ T C+L C S + ++ KVPA + SVVCP +S C + TCC + G + CCPY A CCSD HCCP NT C+L+ G C S V ++ ++S V+CPDQ S C DG+TCC + G++ CCP +AVCCSD HCCP+ T C+L TC S + + + + L++ C + S C G+TCC S G +GCCP AVCC D L CCP TVCNL A TCD S + LL T PG Y+ +G+ TCC+ AG + CCP A CC D IHCCP T+CN+ TCD + + P L +E KC ++C + TCC +++ ++CCP P AVCCSD HCCP C+ ++C++ P P Sbjct: 69 DGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQ-KVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEARV---EPIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPC-NASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNT-----------PGFPYRSENGRCDESASCPGEATCCRTRAG-GWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGMEEEKCGKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWRQKLP 517 HSP 2 Score: 273.863 bits (699), Expect = 1.736e-82 Identity = 164/398 (41.21%), Postives = 222/398 (55.78%), Query Frame = 3 Query: 417 VPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSI---------LSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK---TKKPSLLIKTFQP---NPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH-QAEALEIKIS-----PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538 +P + + +V+CPDQ S+C D +TCC + GS+ CCP+ AVCC D+RHCCP+ T C+L C S + ++ KVPA + SVVCP +S C + TCC + G + CCPY A CCSD HCCP NT C+L+ G C S V ++ + S + CPD S C G TCC L++G++GCCP NAVCCSD + CCP+ T C+L+ TC S T + ++ + P +PV + P A C+DG TCC+ G +GCCP A CC D +HCCP TVCN+ TCD AL +S P E+ +C + C + TCC + ++CCP P AVCC DH HCCPN T C+L ++CD L P+ Sbjct: 41 LPHTRVGAVICPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQ-KVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEARV---EPIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQ-WGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPL 433 HSP 3 Score: 265.388 bits (677), Expect = 2.349e-79 Identity = 174/494 (35.22%), Postives = 234/494 (47.37%), Query Frame = 3 Query: 147 VYRFSREFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPAS-------SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSV--VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD--SKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS--------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 V + ++PI + P V+ S+C DG++CC +G++ CCP +AVCCSD HCCP+ T C+L TC S + + V + L+V C C DGSTCC + G + CCP AVCC D HCCP TVCNL A TCD +T + P S C + + C +TCC G +ACCP AVCC D HCCP T+CNL+A TCD S L + + + + + E + C TCC S G + CCP AVCCSD CCP+ CN TC+ + K P+L ++ Q PV A+ C TCC + +GCCP A CC D HCCP+ C ++ +C + + P V +KC N S C TCCP + CCP AVCC+DH HCCP + +C++ T +C+K P+ P Sbjct: 187 VCKSGEARVEPIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGMEEEKCGKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWRQKLPALQQRSGQTGPVENKC--DAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRGSHVVPWFTKVGALTEPSGVTDVKCDNKSSCASGTTCCPLQTGGWGCCPLVKAVCCADHEHCCPQSYTCNMQTGTCEKKAGQGLPLSRVVP 678 HSP 4 Score: 264.618 bits (675), Expect = 4.511e-79 Identity = 172/449 (38.31%), Postives = 217/449 (48.33%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPAS-------SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK----------TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD----------HQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSAND-SYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 + T G + CCPY A CCSD HCCP NT C+L +G C S V ++ ++S V+CPDQ S C DG+TCC + G++ CCP +AVCCSD HCCP+ T C+L TC S + + V + L+V C C DGSTCC + G + CCP AVCC D HCCP TVCNL A TCD +T + P S D S++C ATCC G + CCP AVCC D + CCP T+CNL A TCD TK+P L + +CPG TCCK +G + CCP A CCSD HCCP+ CN TC+ + AL+ + KC + C + TCC + CCP P AVCC D +HCCP SC + SC + Sbjct: 151 LLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEARVE---PIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGMEEEKCGKDAVCPGRT-------TCCKNSSGQ-WACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWRQKLPALQQRSGQTGPVENKCDAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRG 588 HSP 5 Score: 233.417 bits (594), Expect = 1.540e-67 Identity = 156/447 (34.90%), Postives = 208/447 (46.53%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSV--VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP------DGSSTCKTGATCCLLSDG-SYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT---FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAE-----ALEIKISPILVESIKCPN-GSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532 + G + CCP AVCC D HCCP T CNL TCD +T + P S C + + C +TCC G +ACCP AVCC D HCCP T+CNL+A TCD L + + +L + + C + C +TCC + G +ACCP AVCCSD HCCP+ CN TC+ + + K+PA+ S + D ++C TCC + +GCCP AVCC D CCP+ C +C + K +P+ V V C K C+ G TCC L G +GCCP A CC+D HCCPQ+ CN+ GTC+ +A + + P + + C G C ++ TCC + ++ CCP P AVCC D HCCP SC L C L + Sbjct: 310 SRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRL---TAGMEEEKCGKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSL-PWRQKLPALQQRSGQTGPVENKCDAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRGSHVVPWFTKVGALTEPSGVTDVKC-DNKSSCASGTTCCPLQTG-GWGCCPLVKAVCCADHEHCCPQSYTCNMQTGTCEKKAGQGLPLSRVVPAQPQDTQDVPCDGTGEFKCPKQNTCCRISATAWGCCPSPGAVCCMDSKHCCPAGYSCDLKAGGCTLGPRLSW 750 HSP 6 Score: 223.787 bits (569), Expect = 5.474e-64 Identity = 130/330 (39.39%), Postives = 182/330 (55.15%), Query Frame = 3 Query: 645 VPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA---------ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC----DHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF-PIINFHP*FNYY 1568 +P + + +V+CPDQ S+C D +TCC + GS+ CCP+ AVCC D+RHCCP+ T C+L C S + ++ K+PA + S+ CP G S+C TCCLL+ G +GCCP+ A CCSD L CCP NT C+L G C S + I+ +P + V+CP + C DG TCC+L G ++GCCP A CCSD +HCCP+ T C++ TC AEA+ + +S P+ ++ C C TCC ++ + CCP P AVCC DH HCCP+ T C+L +CD P+++ P F Y Sbjct: 41 LPHTRVGAVICPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQ-KVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEAR-VEPIRAVSASPED-VLCPDQRSMCPDGTTCCQLNNG-TFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYR 366 HSP 7 Score: 59.3066 bits (142), Expect = 8.798e-9 Identity = 34/102 (33.33%), Postives = 46/102 (45.10%), Query Frame = 3 Query: 1251 CPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 CP VC + + V ++ CP+ S C + TCC + S+ CCP+P AVCC D HCCP T+C L C L FP++ P Sbjct: 17 CPDGAVCADGHKCFLNSHGGFTCPLPHTRVGAVICPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQKVP 118
BLAST of Granulin b vs. Ensembl Medaka
Match: grna (granulins [Source:NCBI gene;Acc:101162601]) HSP 1 Score: 284.263 bits (726), Expect = 1.814e-84 Identity = 177/443 (39.95%), Postives = 235/443 (53.05%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ SN+S++ D GS++C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + K+S + +E + C + C + TCC + + ++ CCP P AVCC DH HCCP T+C L+T SC K Sbjct: 311 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGST-SCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLK 744 HSP 2 Score: 258.84 bits (660), Expect = 3.171e-75 Identity = 171/498 (34.34%), Postives = 237/498 (47.59%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC----DSVL--------------------KEV------------VTKIKLKVPASSILS------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 +G ++CCP AVCC DK HCCP+ T C++ + C D L KEV ++ P + L + C + + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ SN+S++ DGS++C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 189 EGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 680 HSP 3 Score: 250.366 bits (638), Expect = 3.459e-72 Identity = 174/491 (35.44%), Postives = 227/491 (46.23%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLS-------AGTCDSKTKKP---------SLLIKTFQP------NPVNR----------------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIK-------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*F 1559 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ S +S++ D GS++C TCC DG++GCCP AVCC D CCP T C+LS +G K P S L+KT Q P +R +I + QC TCC + +GCCP A CC+D HCCP + C +C + +SI+ C C + +CC + CCP PNAVCC D HCCP +C L +KSC K + L+ + P F Sbjct: 469 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTCDLASKSCHKLLTLQLETVPLTPVF 953 HSP 4 Score: 224.942 bits (572), Expect = 3.045e-63 Identity = 157/501 (31.34%), Postives = 230/501 (45.91%), Query Frame = 3 Query: 279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV------LKEVVTKIKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA--------------ISNLSIE------------------CPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 Y CCP+ A CC D HCCP++ C++ +C + ++ V +++ + ++ +CPDQS+C C A Y CCP + V C D +HCCP+ C+LD+ +C V SI +V+C D S+C D +TCC G +ACCP AVCC DK HCCP+ T C+++ C S + + M K PA +S +++E +GSS +C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 40 YDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC--------------VKKESIKTVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKAL-PMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 522 HSP 5 Score: 217.624 bits (553), Expect = 9.820e-61 Identity = 165/507 (32.54%), Postives = 230/507 (45.36%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV-VTKMKLKIPAISNLS----------------------------------------IECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICP-------GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIK---ISPILVESIKCPNGSL------------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FN 1562 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G++ CCP AVCC D HCCP T C+L +C LK + M K+PA + S I C D + C TCC + +GCCP AVCC+D CCP + C D+ K ++I + P I A +QC + +CC+L G+ +GCCP A CC DK HCCP+ C++ +C H+ L+++ ++P+ + + +G + C TCC +++ ++ CC P AVCC D HCCP+ C+ SC KN L + +N+H F Sbjct: 548 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC---LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISC-DSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEE----DTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGE-WGCCPLPNAVCCGDKEHCCPEGYTCDLASKSC-HKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHW--LNWHTFFT 1037 HSP 6 Score: 191.815 bits (486), Expect = 7.672e-52 Identity = 130/451 (28.82%), Postives = 200/451 (44.35%), Query Frame = 3 Query: 417 VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------------QPNPVNRVICPGAKYQ------------------------------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 V + + + +CP+ +C G TCC Y CCP+ A CC D HCCP++ +C++ +C + ++ V +++ + ++ +CPDQS+C C A Y CCP + V C D +HCCP+ C+LD+ +C V K +K ++ C DG S C TCC +G + CCP AVCC DK+ CCP+ T C++ C S + K + F + V+ V G + + C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + K+S + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 10 VSLALVAADMCPNGGKCEKGQTCCQSPSKDYDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC-------VKKESIK-------TVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 443 HSP 7 Score: 129.028 bits (323), Expect = 6.619e-31 Identity = 103/351 (29.34%), Postives = 142/351 (40.46%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----------------------------------------VVCPDQSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI 1130 T DG++ CCP AVCC D +HCCP T C+L+ +C + + + K+PAS+ S + C +QC +TCC + + CCP AVCC+D HCCP + C + +C EVV K+PA+ + V C QC + +CC + G + CCP +AVCC DK HCCP+ TCD K + L++ + + PD S +C TCC S ++GCC AVCC D CCP C G+C T L TF N +I Sbjct: 706 TKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC--LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKG--EVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGY-------TCDLASKSCHKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHWLNWHTFFTNKRKAII 1044
BLAST of Granulin b vs. Ensembl Medaka
Match: grna (granulins [Source:NCBI gene;Acc:101162601]) HSP 1 Score: 281.952 bits (720), Expect = 2.406e-83 Identity = 176/443 (39.73%), Postives = 234/443 (52.82%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ S +S++ D GS++C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + K+S + +E + C + C + TCC + + ++ CCP P AVCC DH HCCP T+C L+T SC K Sbjct: 390 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLK 823 HSP 2 Score: 278.1 bits (710), Expect = 7.361e-82 Identity = 173/457 (37.86%), Postives = 235/457 (51.42%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ SN+S++ DGS++C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 311 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 759 HSP 3 Score: 260.766 bits (665), Expect = 1.119e-75 Identity = 173/499 (34.67%), Postives = 240/499 (48.10%), Query Frame = 3 Query: 270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC----DSVL--------------------KEV------------VTKIKLKVPASSILS------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 +G ++CCP AVCC DK HCCP+ T C++ + C D L KEV ++ P + L + C + + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ SN+S++ DGS++C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + K+S + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 189 EGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 680 HSP 4 Score: 250.751 bits (639), Expect = 3.302e-72 Identity = 174/491 (35.44%), Postives = 227/491 (46.23%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLS-------AGTCDSKTKKP---------SLLIKTFQP------NPVNR----------------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIK-------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*F 1559 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M K+P+ S +S++ D GS++C TCC DG++GCCP AVCC D CCP T C+LS +G K P S L+KT Q P +R +I + QC TCC + +GCCP A CC+D HCCP + C +C + +SI+ C C + +CC + CCP PNAVCC D HCCP +C L +KSC K + L+ + P F Sbjct: 548 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTCDLASKSCHKLLTLQLETVPLTPVF 1032 HSP 5 Score: 225.328 bits (573), Expect = 3.471e-63 Identity = 157/501 (31.34%), Postives = 230/501 (45.91%), Query Frame = 3 Query: 279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV------LKEVVTKIKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA--------------ISNLSIE------------------CPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 Y CCP+ A CC D HCCP++ C++ +C + ++ V +++ + ++ +CPDQS+C C A Y CCP + V C D +HCCP+ C+LD+ +C V SI +V+C D S+C D +TCC G +ACCP AVCC DK HCCP+ T C+++ C S + + M K PA +S +++E +GSS +C TCC +G +GCCPF AVCC D + CCP+ CNL+A TC+ +L K + V V C G+ C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 40 YDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC--------------VKKESIKTVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKAL-PMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 522 HSP 6 Score: 218.009 bits (554), Expect = 9.348e-61 Identity = 165/507 (32.54%), Postives = 230/507 (45.36%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV-VTKMKLKIPAISNLS----------------------------------------IECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICP-------GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIK---ISPILVESIKCPNGSL------------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FN 1562 T +G + CCP+ AVCC D HCCP+ CNL TC+ V + KVP+ S +SV D + C D +TCC G + CCP+ AVCC D HCCP+ CNL A TC+ V M KVP+ S +SV D + C D +TCC G++ CCP AVCC D HCCP T C+L +C LK + M K+PA + S I C D + C TCC + +GCCP AVCC+D CCP + C D+ K ++I + P I A +QC + +CC+L G+ +GCCP A CC DK HCCP+ C++ +C H+ L+++ ++P+ + + +G + C TCC +++ ++ CC P AVCC D HCCP+ C+ SC KN L + +N+H F Sbjct: 627 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC---LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISC-DSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEE----DTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGE-WGCCPLPNAVCCGDKEHCCPEGYTCDLASKSC-HKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHW--LNWHTFFT 1116 HSP 7 Score: 192.2 bits (487), Expect = 7.647e-52 Identity = 130/451 (28.82%), Postives = 200/451 (44.35%), Query Frame = 3 Query: 417 VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------------QPNPVNRVICPGAKYQ------------------------------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544 V + + + +CP+ +C G TCC Y CCP+ A CC D HCCP++ +C++ +C + ++ V +++ + ++ +CPDQS+C C A Y CCP + V C D +HCCP+ C+LD+ +C V K +K ++ C DG S C TCC +G + CCP AVCC DK+ CCP+ T C++ C S + K + F + V+ V G + + C D TCCK G +GCCP+ A CC D IHCCP+ CN+ TC+ ++ + K+S + +E + C + C + TCC + + CCP+P AVCC D HCCP +C+L ++C+ + +L K P + Sbjct: 10 VSLALVAADMCPNGGKCEKGQTCCQSPSKDYDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC-------VKKESIK-------TVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 443 HSP 8 Score: 129.028 bits (323), Expect = 6.393e-31 Identity = 103/351 (29.34%), Postives = 142/351 (40.46%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----------------------------------------VVCPDQSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI 1130 T DG++ CCP AVCC D +HCCP T C+L+ +C + + + K+PAS+ S + C +QC +TCC + + CCP AVCC+D HCCP + C + +C EVV K+PA+ + V C QC + +CC + G + CCP +AVCC DK HCCP+ TCD K + L++ + + PD S +C TCC S ++GCC AVCC D CCP C G+C T L TF N +I Sbjct: 785 TKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC--LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKG--EVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGY-------TCDLASKSCHKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHWLNWHTFFTNKRKAII 1123
BLAST of Granulin b vs. Ensembl Medaka
Match: ENSORLT00000029765.1 (granulins [Source:NCBI gene;Acc:101168633]) HSP 1 Score: 102.064 bits (253), Expect = 9.957e-24 Identity = 82/273 (30.04%), Postives = 112/273 (41.03%), Query Frame = 3 Query: 405 IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVV-----TKMKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------------------DSKLKEVVTKMKLKIPAISNLS--------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC 1061 + L V + S+ CPD C D STCC + G ++CCP AVCCSDK HCCP CNL C+ + V TK + P + LS V C C D +TCC G++ CCPY CC D HCCP C+L C S +E +++ + A++ S I C D C G +CC ++G + CCP+ CC+D CC C+ ++ TC Sbjct: 10 VGLSVCGFAFCSIECPDGKLCPDLSTCC-LTGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRC-DSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 280 HSP 2 Score: 100.523 bits (249), Expect = 3.053e-23 Identity = 81/277 (29.24%), Postives = 111/277 (40.07%), Query Frame = 3 Query: 861 MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS----LLIKTFQPNPVNRVICPG---------------------AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------------------------DHQAEALEIKISPILVES--------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514 + L + + SIECPDG C +TCCL G + CCP AVCCSDK CCP CNL+ C+ KT +P +L K P + + Y C D TCC+ P G ++ CCPY CC D HCCP C++ C + + LE ++ + S I+C + C +CC A ++CCPYP CC+D HCC +C + +C K Sbjct: 10 VGLSVCGFAFCSIECPDGK-LCPDLSTCCLTGHG-FSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCE-KTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKG-AWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATCRK 282 HSP 3 Score: 96.2857 bits (238), Expect = 8.857e-22 Identity = 74/242 (30.58%), Postives = 97/242 (40.08%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-----VLKEVVTKIKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------DSKLKEVVTKMKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 830 T +SCCP AVCCSDK HCCP CNL C+ V ++TK + P + LS V C C D +TCC G++ CCPY CC D HCCP C+L C +L++ +T + A S V+ C + C G++CC A G + CCPY CC+D RHCC C+ + TC Sbjct: 39 TGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 280
BLAST of Granulin b vs. Ensembl Medaka
Match: ENSORLT00000005071.2 (granulins [Source:NCBI gene;Acc:101168633]) HSP 1 Score: 102.064 bits (253), Expect = 1.032e-23 Identity = 82/273 (30.04%), Postives = 112/273 (41.03%), Query Frame = 3 Query: 405 IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVV-----TKMKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------------------DSKLKEVVTKMKLKIPAISNLS--------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC 1061 + L V + S+ CPD C D STCC + G ++CCP AVCCSDK HCCP CNL C+ + V TK + P + LS V C C D +TCC G++ CCPY CC D HCCP C+L C S +E +++ + A++ S I C D C G +CC ++G + CCP+ CC+D CC C+ ++ TC Sbjct: 12 VGLSVCGFAFCSIECPDGKLCPDLSTCC-LTGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRC-DSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 282 HSP 2 Score: 102.064 bits (253), Expect = 1.062e-23 Identity = 83/285 (29.12%), Postives = 115/285 (40.35%), Query Frame = 3 Query: 861 MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS----LLIKTFQPNPVNRVICPG---------------------AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------------------------DHQAEALEIKISPILVES--------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538 + L + + SIECPDG C +TCCL G + CCP AVCCSDK CCP CNL+ C+ KT +P +L K P + + Y C D TCC+ P G ++ CCPY CC D HCCP C++ C + + LE ++ + S I+C + C +CC A ++CCPYP CC+D HCC +C + +C K L +P+ Sbjct: 12 VGLSVCGFAFCSIECPDGK-LCPDLSTCCLTGHG-FSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCE-KTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKG-AWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATCRK---LSYPV 289 HSP 3 Score: 96.2857 bits (238), Expect = 8.942e-22 Identity = 74/242 (30.58%), Postives = 97/242 (40.08%), Query Frame = 3 Query: 267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-----VLKEVVTKIKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------DSKLKEVVTKMKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 830 T +SCCP AVCCSDK HCCP CNL C+ V ++TK + P + LS V C C D +TCC G++ CCPY CC D HCCP C+L C +L++ +T + A S V+ C + C G++CC A G + CCPY CC+D RHCC C+ + TC Sbjct: 41 TGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 282
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000029882.1 (SMESG000029882.1) HSP 1 Score: 822.002 bits (2122), Expect = 0.000e+0 Identity = 420/427 (98.36%), Postives = 424/427 (99.30%), Query Frame = 3 Query: 273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553 GSY+CCPYSSAVCCSDK+HCCPQNT CNL+ GTCDS LKEVVTK+KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP Sbjct: 288 GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 714 HSP 2 Score: 665.996 bits (1717), Expect = 0.000e+0 Identity = 373/495 (75.35%), Postives = 412/495 (83.23%), Query Frame = 3 Query: 96 MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQP-NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA----LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-------LLKFPIIN 1544 MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNCPDDSVCDDGSSCCVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQC+DGS+CC +A G+YACCPYSSAVCCSDK+HCCPQNTVCNL AGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCC VAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK+PA S LS+ CPD S C G+TCC ++ GSY CCP+S+AVCCSDK CCPQNTVCNL AGTCDSK K+ +K P + + V+CP + QC+DG TCC + AG SY CCPYS+A CCSDK HCCPQNTVCN++ GTCD + + +++K+ + S+ CP+ S C TCC A SY+CCPY +AVCCSD HCCP NT C+L+ +CD + LK P I+ Sbjct: 1 MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNCPDDSVCDDGSSCCVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCDDGSSCCVMADGNYACCPYSSAVCCSDKQHCCPQNTVCNLSAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCEVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCEVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS 492 HSP 3 Score: 188.734 bits (478), Expect = 9.475e-52 Identity = 108/211 (51.18%), Postives = 139/211 (65.88%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS 887 + +DGSY CCP+S+AVCCSDK CCPQNT CNL+ GTCDS K+ IK P + + V+CP + QC+DG TCC + AG SY CCPYS+A CCSDK HCCPQNTVCN++ GTCD + + +++K+ + S+ CP+ S C TCC A SY+CCPY +AVCCSD HCCP NT C+L+ +CD + LK P I+ Sbjct: 513 LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQP-NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA----LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-------LLKFPIIN 711
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1) HSP 1 Score: 224.557 bits (571), Expect = 3.013e-65 Identity = 157/496 (31.65%), Postives = 244/496 (49.19%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLK-VPASSILSV--------------VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS---------KTKKPSLLIKTF--QPNPVNRV-ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-----DHQAEALEIKISPILVESIKCP-NGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC---DKNILLKFPI 1538 VT GSY CC +++AVCC DK HCCP+ + C+ + C + +++++ +K++ P ++IL +CP+ +++C + TCC SY CC Y++AVCC DK HCCP T CN + S ++ M++ V + + ++ CP+ +++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++ +++ +K++ +N+ + CP+ + CK TCC+ +Y CCP NAVCCSDK CCP+ T C++ C S L+ +F + N + + G K + S C + G S G C +SA TCCSD CCPQ+T C+ C D E + + + ++ CP N + C TCC ++ SY CC NAVCC+D CCP+N C + T SC + N FP+ Sbjct: 120 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRS-GRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPL 614 HSP 2 Score: 217.624 bits (553), Expect = 9.481e-63 Identity = 152/495 (30.71%), Postives = 235/495 (47.47%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIK-----LKVPASS------ILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-VPASSILSV--------------VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKK--------PSLLIKT--------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV-ESIKCPNGS------LCGQKGTC------CPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 T SY CC Y++AVCC DK HCCP T C+ C+ ++ + I+ +++P I CP+ +++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++++++ +K++ P ++IL +CP+ +++C + TCC SY CC Y++AVCC DK HCCP T C+ C+ ++ + ++ +++P I ++ CP+ + C+ TCC+ GSY CC F+NAVCC DK CCP+ + C+ C K P+L ++ + N + V+CP K +C D +TCC + ++Y CCP+ A CCSDK CCP+ T C+I C H + +++ L+ +S K L G K CP N C + CCSD CCP +T C C N Sbjct: 33 TKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCC-ITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLN 526 HSP 3 Score: 204.527 bits (519), Expect = 7.618e-58 Identity = 141/468 (30.13%), Postives = 214/468 (45.73%), Query Frame = 3 Query: 402 KIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-------IPAISNLSIE--------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---------------------DHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD------KNILLKFPIINFHP*FNYYLFVF 1580 K+ P + +CP+ +++C + TCC SY CC Y++AVCC DK HCCP T CN + S ++ M++ V + + ++ CP ++++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++++++ +K++ + A N E CP+ + C TCC SY CC ++NAVCC DK CCP T C+ C+ + I+T P P+ + CP + +C D QTCC G SY CC ++ A CC DK HCCP+ + C+ + C + + LE K++ + + CPN + C TCC + +++Y CCP+ NAVCCSD CCP T+C + K C I + H F Y F Sbjct: 2 KLNKSAPNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNE--KDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFF 465
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1) HSP 1 Score: 213.001 bits (541), Expect = 8.356e-61 Identity = 158/527 (29.98%), Postives = 245/527 (46.49%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS---------KTKKPSLLIKTF--QPNPVNRV-ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-----DHQAEALEIKISPILVESIKCP-NGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC---DKNILLKFPI 1538 VT GSY CC +++AVCC DK HCCP+ + C+ + C + +++++ +K++ P ++IL V+CP+ +++C + TCC SY CC Y++AVCC DK HCCP T CN + S ++ M++ V + + ++ CP ++++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++ +++ +K++ +N+ + CP+ + CK TCC+ +Y CCP NAVCCSDK CCP+ T C++ C S L+ +F + N + + G K + S C + G S G C +SA TCCSD CCPQ+T C+ C D E + + + ++ CP N + C TCC ++ SY CC NAVCC+D CCP+N C + T SC + N FP+ Sbjct: 120 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRS-GRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPL 645 HSP 2 Score: 206.453 bits (524), Expect = 2.153e-58 Identity = 153/526 (29.09%), Postives = 236/526 (44.87%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIK-----LKVPASS------ILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKK--------PSLLIKT--------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV-ESIKCPNGS------LCGQKGTC------CPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 T SY CC Y++AVCC DK HCCP T C+ C+ ++ + I+ +++P I CP+ +++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++++++ +K++ P ++IL V+CP+ +++C + TCC SY CC Y++AVCC DK HCCP T C+ C+ ++ + ++ +++P I ++ CP+ + C+ TCC+ GSY CC F+NAVCC DK CCP+ + C+ C K P+L ++ + N + V+CP K +C D +TCC + ++Y CCP+ A CCSDK CCP+ T C+I C H + +++ L+ +S K L G K CP N C + CCSD CCP +T C C N Sbjct: 33 TKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCC-ITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLN 557 HSP 3 Score: 194.897 bits (494), Expect = 3.853e-54 Identity = 135/469 (28.78%), Postives = 211/469 (44.99%), Query Frame = 3 Query: 402 KIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCP-------------------------------------FSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---------------------DHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508 K+ P + +CP+ +++C + TCC SY CC Y++AVCC DK HCCP T CN + S ++ M++ V + + ++ CP ++++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++++++ +K++ +N+ + CP+ + CK TCC+ +Y CCP ++NAVCC DK CCP T C+ C+ + I+T P P+ + CP + +C D QTCC G SY CC ++ A CC DK HCCP+ + C+ + C + + LE K++ + + CPN + C TCC + +++Y CCP+ NAVCCSD CCP T+C + K C Sbjct: 2 KLNKSAPNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNE--KDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKC 466 HSP 4 Score: 167.933 bits (424), Expect = 1.248e-44 Identity = 108/312 (34.62%), Postives = 160/312 (51.28%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA--------SSILS--------VVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK---LKEVVTKM---------KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTF 1103 VT GSY CC +++AVCC DK HCCP+ + C+ + C K V KL +PA ++IL V+CP+ +++C D TCC +Y CCP+ +AVCCSDK CCP+ T C++ C S + E+ +M K + I+S++ + + + C + G C +S+ CCSD R CCPQ+T C+ C + T+ P + LS + CPD + C + TCC +SD SYGCC NAVCC+D++SCCP N C++ +C ++ + K TF Sbjct: 337 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKL-IPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPLTF 647 HSP 5 Score: 119.783 bits (299), Expect = 2.895e-28 Identity = 92/298 (30.87%), Postives = 126/298 (42.28%), Query Frame = 3 Query: 858 KMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAE----------ALEIKISP---ILV------ESIKCPNG--------------------------------------SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPI 1538 K+ P + CP+ + C TCC SY CC ++NAVCC DK CCP T C+ C+ + I+T P P+ + CP + +C D QTCC G SY CC ++ A CC DK HCCP+ + C+ + C A+ AL+++ P IL + + CPN + C ++ TCC + ++SY CC Y NAVCC D HCCPN TSC K C++NI K PI Sbjct: 2 KLNKSAPNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPI 297
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1) HSP 1 Score: 213.386 bits (542), Expect = 8.669e-61 Identity = 158/527 (29.98%), Postives = 245/527 (46.49%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS---------KTKKPSLLIKTF--QPNPVNRV-ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-----DHQAEALEIKISPILVESIKCP-NGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC---DKNILLKFPI 1538 VT GSY CC +++AVCC DK HCCP+ + C+ + C + +++++ +K++ P ++IL V+CP+ +++C + TCC SY CC Y++AVCC DK HCCP T CN + S ++ M++ V + + ++ CP ++++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++ +++ +K++ +N+ + CP+ + CK TCC+ +Y CCP NAVCCSDK CCP+ T C++ C S L+ +F + N + + G K + S C + G S G C +SA TCCSD CCPQ+T C+ C D E + + + ++ CP N + C TCC ++ SY CC NAVCC+D CCP+N C + T SC + N FP+ Sbjct: 149 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRS-GRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPL 674 HSP 2 Score: 206.453 bits (524), Expect = 2.841e-58 Identity = 153/526 (29.09%), Postives = 235/526 (44.68%), Query Frame = 3 Query: 264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIK-----LKVPASS------ILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC----DSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV-ESIKCPNGS------LCGQKGTC------CPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517 T SY CC Y++AVCC DK HCCP T C+ C+ ++ + I+ +++P I CP+ +++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++++++ +K++ P ++IL V+CP+ +++C + TCC SY CC Y++AVCC DK HCCP T C+ C+ ++ + ++ +++P I ++ CP+ + C+ TCC+ GSY CC F+NAVCC DK CCP+ + C+ C S + L+ I + N + V+CP K +C D +TCC + ++Y CCP+ A CCSDK CCP+ T C+I C H + +++ L+ +S K L G K CP N C + CCSD CCP +T C C N Sbjct: 62 TKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCC-ITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLN 586 HSP 3 Score: 191.43 bits (485), Expect = 8.662e-53 Identity = 133/455 (29.23%), Postives = 207/455 (45.49%), Query Frame = 3 Query: 444 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCP-------------------------------------FSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---------------------DHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508 +CP+ +++C + TCC SY CC Y++AVCC DK HCCP T CN + S ++ M++ V + + ++ CP ++++C D TCC GSY CC +++AVCC DK HCCP+ + C+ C + ++++++ +K++ +N+ + CP+ + CK TCC+ +Y CCP ++NAVCC DK CCP T C+ C+ + I+T P P+ + CP + +C D QTCC G SY CC ++ A CC DK HCCP+ + C+ + C + + LE K++ + + CPN + C TCC + +++Y CCP+ NAVCCSD CCP T+C + K C Sbjct: 45 ICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNE--KDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKC 495 HSP 4 Score: 167.933 bits (424), Expect = 1.618e-44 Identity = 108/312 (34.62%), Postives = 160/312 (51.28%), Query Frame = 3 Query: 261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA--------SSILS--------VVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK---LKEVVTKM---------KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTF 1103 VT GSY CC +++AVCC DK HCCP+ + C+ + C K V KL +PA ++IL V+CP+ +++C D TCC +Y CCP+ +AVCCSDK CCP+ T C++ C S + E+ +M K + I+S++ + + + C + G C +S+ CCSD R CCPQ+T C+ C + T+ P + LS + CPD + C + TCC +SD SYGCC NAVCC+D++SCCP N C++ +C ++ + K TF Sbjct: 366 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKL-IPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPLTF 676 HSP 5 Score: 150.599 bits (379), Expect = 1.676e-38 Identity = 103/319 (32.29%), Postives = 154/319 (48.28%), Query Frame = 3 Query: 672 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC--------DSKTKKPSLLIK--------TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPI 1538 +CP+ +++C + TCC SY CC Y++AVCC DK HCCP T C+ C+ ++ + ++ +++P I ++ CP+ + C+ TCC+ GSY CC F+NAVCC DK CCP+ + C+ C + + P+L ++ + N + V+CP K +C D +TCC + ++Y CCP+ + TV NI CPN + C ++ TCC + ++SY CC Y NAVCC D HCCPN TSC K C++NI K PI Sbjct: 45 ICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCC-ITKHNNYYCCPHKNN-----------KETVGNI-------------------------CPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPI 326
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018770.1 (SMESG000018770.1) HSP 1 Score: 206.838 bits (525), Expect = 1.547e-60 Identity = 133/395 (33.67%), Postives = 194/395 (49.11%), Query Frame = 3 Query: 444 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL----------KEVVTKMKLKVPASSIL-------------SVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------DSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV--ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487 VCP+ +++C + TCC SY CC Y +A+CC DK HCCP + C+ C + + + KM P+S++ + CP ++++C D TCC G+Y CCP+ +AVCCSDK +CCP+NT C+L C + LK + + L +CP+ C CC +S G +GCC F+ +CC D +CCP NT C+ + C SK+ + + QP ++ ICP +C +TCC + G YGCCP+ ATCCSD CCP N VC++ K C + ++++L S I ++ I CP+ + C CC ++ Y CC Y N VCC+D CCPN T C Sbjct: 33 VCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSSAVFNSYKNPGLKSANLYTFYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTEIPNELQPEAQIKLNNICPDKHVECQSFETCCSVGDG-LYGCCPFKNATCCSDNASCCPHNKVCDLEKKVCKNKETSQPSITKSKSLLHFYSEIGLKVI-CPDQTKCENDSVCCQMDDNQYGCCSYKNGVCCADKQTCCPNGTQC 425 HSP 2 Score: 202.986 bits (515), Expect = 4.563e-59 Identity = 144/431 (33.41%), Postives = 211/431 (48.96%), Query Frame = 3 Query: 105 FIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS---------VLKEVVTKIKLKVPASSIL--------------SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVT-KMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-TKKPSLL----IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVC 1271 I +++ + ++ F++ ++E N+ V + + C + +CCVT SY CC Y +A+CC DK HCCP + C+ K C V++E + L + SS L + CP+ +++C D TCC G+Y CCP+ +AVCCSDK +CCP+NT C+L C + LK + L CP+ + QC CC ++GG + CC ++ +CC D + CCP NT C+ C SK ++ +L+ A L+ CPD C++ TCC + DG YGCCPF NA CCSD SCCP N VC+L C +K T +PS+ + F +VICP + +C + CC++ + YGCC Y CC+DK CCP T C Sbjct: 1 MILTIIVDYALTDGIFSFNKASQDQVSEKNE----NVCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSSAVFNSYKNPGLKSANLYTFYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTEIPNELQPEAQIKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVCKNKETSQPSITKSKSLLHFYSEIGLKVICPD-QTKCENDSVCCQM-DDNQYGCCSYKNGVCCADKQTCCPNGTQC 425 HSP 3 Score: 154.451 bits (389), Expect = 3.201e-41 Identity = 113/332 (34.04%), Postives = 161/332 (48.49%), Query Frame = 3 Query: 672 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----DSKLKEVVTKMKLKIPAIS-------------------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKT-----KKPSL----LIKTFQPNPVNRV--ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPII 1541 VCP+ +++C + TCC SY CC Y +A+CC DK HCCP + C+ C + ++ V + L + + N I CP+ + CK TCC+ G+Y CCP NAVCCSDK +CCP+NT C+L C DS K P L L + V+++ CP ++ QC + CC + +G +GCC ++ CC D CCP NT C+ K C ++ L E++ + + CP+ + C TCC + Y CCP+ NA CCSD++ CCP+N C L K C KN P I Sbjct: 33 VCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSSAVFNSYKNPGLKSANLYTFYSLLNVDKLEKKCPNSEKQCPGQKKCCPM-SGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTEIPNELQPEAQIKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVC-KNKETSQPSI 362 HSP 4 Score: 87.8113 bits (216), Expect = 2.680e-18 Identity = 59/163 (36.20%), Postives = 77/163 (47.24%), Query Frame = 3 Query: 1104 QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---------------LEIKISPILV------------ESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508 Q + N +CP + +C + QTCC + +SY CC Y A CC DK HCCP + C+ K C E L++K S L + I CPN + C TCC + + +Y CCP+ NAVCCSD +CCP NT C L K C Sbjct: 25 QVSEKNENVCPNNRTKCKETQTCC-VTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKC 186 The following BLAST results are available for this feature:
BLAST of Granulin b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Granulin b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of Granulin b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of Granulin b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Granulin b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of Granulin b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 4
BLAST of Granulin b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Granulin b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Granulin b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Granulin b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 2
BLAST of Granulin b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Granulin b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 1
BLAST of Granulin b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Granulin b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035642 ID=SMED30035642|Name=Granulin b|organism=Schmidtea mediterranea sexual|type=transcript|length=1667bpback to top protein sequence of SMED30035642-orf-1 >SMED30035642-orf-1 ID=SMED30035642-orf-1|Name=SMED30035642-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=487bp MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNCPDDSVCDDback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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