Granulin b

Overview
NameGranulin b
Smed IDSMED30035642
Length (bp)1667
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Granulin b (SMED30035642) t-SNE clustered cells

Violin plots show distribution of expression levels for Granulin b (SMED30035642) in cells (dots) of each of the 12 neoblast clusters.

 

back to top


 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Granulin b (SMED30035642) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Granulin b (SMED30035642) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top


 

Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020




SMED30035642

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 20

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30035642h1SMcG0002769 Contig2381GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30035642h1SMcG0002769 Contig2381GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30035642h1SMcG0009313 PL06004A1G01smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30035642h1SMcG0009313 PL06004A1G01smed_ncbi_20240424PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30035642h1SMcG0009313 Contig2381GPL15192PMID:23079596
Forsthoefel et al., 2012
whole organism asexual adult colorimetric in situ hybridization evidence
intestinal phagocyteSMED30035642h1SMcG0009313 Contig2381GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30035642h1SMcG0002769 Contig2381GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30035642h1SMcG0009313 dd_Smed_v4_442_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30035642h1SMcG0009313 dd_Smed_v4_442_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035642h1SMcG0009313 dd_Smed_v4_442_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035642h1SMcG0009313 dd_Smed_v4_442_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30035642h1SMcG0009313 dd_Smed_v4_442_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035642h1SMcG0009313 dd_Smed_v4_442_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035642h1SMcG0009313 Contig2381GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035642h1SMcG0009313 Contig48299uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035642h1SMcG0009313 Contig48299newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30035642h1SMcG0009313 dd_Smed_v4_162_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035642h1SMcG0009313 dd_Smed_v4_162_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
intestinal phagocyteSMED30035642h1SMcG0009313 dd_Smed_v6_442_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035642h1SMcG0009313 dd_Smed_v6_442_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 265.003 bits (676), Expect = 1.961e-80
Identity = 165/449 (36.75%), Postives = 223/449 (49.67%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI-------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV-------ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            V  DGS+ CCP   A CC D+ HCCP    C+L    C  +       +  K+PA           SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA ++  V C  +  C DG TCC +  G++ CCP++ AVCC D  HCCP    C+   GTC+    +V    K    L +P    L  + P D  S+C +  TCC L+ G +GCCP   AVCCSD   CCPQ   C ++ G C    ++ S ++   +  P  R        I       C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   +C+ +      A  +  SP + V+ ++C  G  C    TCC      ++CCPY   VCC+D  HCCP    C+     C +    ++
Sbjct:  141 VMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRC--ITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 580          

HSP 2 Score: 263.848 bits (673), Expect = 5.108e-80
Identity = 164/445 (36.85%), Postives = 229/445 (51.46%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFP 1535
             T  G+ SCCP+  AV C D  HCCP+   C+ +  +C             +   +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C        L + +   +     +   SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA +   ++C D   +C  G TCC L  G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K         P  + R +       C    TCC+L +G+ +GCCP   A CCSD  HCCPQ   C + +G C   +E +  ++  P    S+  P    C Q        TCCPS   S++CC  P+AVCC D  HCCP   +C++  +SC+K ++   P
Sbjct:   75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQP 504          

HSP 3 Score: 234.187 bits (596), Expect = 8.258e-69
Identity = 144/377 (38.20%), Postives = 193/377 (51.19%), Query Frame = 3
Query:  408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            K     S  L   C   + C+ G +C     G+ +CCP+  AV C D  HCCP+   C+ D  +C  +              +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C +        K++  +   +  A+S+ S+ CPD  S C  G+TCC L  G YGCCP  NA CCSD L CCPQ+TVC+L    C SK    + L+     + V  V C   +  C DG TCC+L +G ++GCCP++ A CC D IHCCP    C+  KGTC+   HQ   +E   + +       L   + C N S C    TCC   +  + CCP P AVCCSDH HCCP   +C
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 410          
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 231.876 bits (590), Expect = 1.278e-69
Identity = 142/392 (36.22%), Postives = 195/392 (49.74%), Query Frame = 3
Query:  408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL------KEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            K     S  L   C   + C+ G +C     G+ +CCP+  AV C D  HCCP+   C+ D  +C  +              +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C +        K++  +   +  A+S+ S+ CPD  S C  G+TCC L  G YGCCP  NA CCSD L CCPQ+TVC+L    C SK    + L+     + V  V C   +  C DG TCC+L +G ++GCCP++ A CC D IHCCP    C+  KGTC+   HQ   +E   + +       L   + C N S C    TCC      ++CCPY   VCC+D  HCCP    C+     C +    ++
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 425          

HSP 2 Score: 209.149 bits (531), Expect = 4.975e-61
Identity = 129/357 (36.13%), Postives = 177/357 (49.58%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC 1292
             T  G+ SCCP+  AV C D  HCCP+   C+ +  +C             +   +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C        L + +   +     +   SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA +   ++C D   +C  G TCC L  G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K         P  + R +       C    TCC+      + CCPY    CC+D+ HCCP    C      C
Sbjct:   75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCR-DNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKC 417          

HSP 3 Score: 186.422 bits (472), Expect = 1.676e-52
Identity = 112/297 (37.71%), Postives = 151/297 (50.84%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI-------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC--------DSKTKKPSL 1088
            V  DGS+ CCP   A CC D+ HCCP    C+L    C  +       +  K+PA           SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA ++  V C  +  C DG TCC +  G++ CCP++ AVCC D  HCCP    C+   GTC+    +V    K    L +P    L  + P D  S+C +  TCC  +   + CCP+   VCC+D+  CCP    C      C        D+  + P+L
Sbjct:  141 VMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRC--ITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPAL 434          
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 214.157 bits (544), Expect = 2.161e-63
Identity = 133/349 (38.11%), Postives = 181/349 (51.86%), Query Frame = 3
Query:  438 SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPY 1430
            SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA ++  V C  +  C DG TCC +  G++ CCP++ AVCC D  HCCP    C+   GTC+    +V    K    L +P    L  + P D  S+C +  TCC L+ G +GCCP   AVCCSD   CCPQ   C ++ G C    ++ S ++   +  P  R      +         C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   +C+ +      A  +  SP + V+ ++C  G  C    TCC      ++CCPY
Sbjct:   19 SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY 360          

HSP 2 Score: 198.364 bits (503), Expect = 2.115e-57
Identity = 120/308 (38.96%), Postives = 165/308 (53.57%), Query Frame = 3
Query:  666 SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA +   ++C D   +C  G TCC L  G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K         P  + R +       C    TCC+L +G+ +GCCP   A CCSD  HCCPQ   C + +G C   +E +  ++  P    S+  P    C Q        TCCPS   S++CC  P+AVCC D  HCCP   +C++  +SC+K ++   P    
Sbjct:   19 SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFL 322          

HSP 3 Score: 192.2 bits (487), Expect = 4.495e-55
Identity = 119/325 (36.62%), Postives = 169/325 (52.00%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD--SKLKEVVTKMKLKIPAISN-LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPY 1214
            G Y CCP  +A CCSD  HCCPQ+T C+L +  C S  +   T +  K+PA ++  V C  +  C DG TCC +  G++ CCP++ AVCC D  HCCP    C+   GTC+        +++    + L  P +    V C + S C    TCC +  G + CCP   AVCCSD +HCCPQ   C +  G C   S++   + KM  +  ++S+   I C D  ++C  G TCC    GS+ CC   +AVCC D+  CCP    CN+ A +C+ +  + +P+  +       V  V C G  + C D QTCC+      + CCPY
Sbjct:   41 GKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGC-DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVEC-GEGHFCHDNQTCCR-DNRQGWACCPY 360          

HSP 4 Score: 162.925 bits (411), Expect = 3.337e-44
Identity = 95/225 (42.22%), Postives = 124/225 (55.11%), Query Frame = 3
Query:  843 KEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            K++  +   +  A+S+ S+ CPD  S C  G+TCC L  G YGCCP  NA CCSD L CCPQ+TVC+L    C SK    + L+     + V  V C   +  C DG TCC+L +G ++GCCP++ A CC D IHCCP    C+  KGTC+   HQ   +E   + +       L   + C N S C    TCC   +  + CCP P AVCCSDH HCCP   +C
Sbjct:    3 KKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 224          

HSP 5 Score: 106.301 bits (264), Expect = 3.487e-24
Identity = 65/169 (38.46%), Postives = 86/169 (50.89%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPY 752
            T G + CCP   AVCCSD QHCCPQ   C + +G C    + V    K+    +S+     + C   + C  G TCC   GGS+ACC    AVCC D++HCCP    CN+ A +C+   KEVV+        + P   +  V C +   C+D  TCC      +ACCPY
Sbjct:  196 TSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCE---KEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY 360          
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 201.445 bits (511), Expect = 4.125e-58
Identity = 130/393 (33.08%), Postives = 182/393 (46.31%), Query Frame = 3
Query:  408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            K     S  L   C   + C+ G +C     G+ +CCP+  AV C D  HCCP+   C+ D  +C  +              +S+ ++ CPD Q +C D STCC +  GS+ CCP   AVCC D  HCCP    C+   GTC+    +V    K    L +P    L  + P D  S+C +  TCC L+ G +GCCP   AVCCSD   CCPQ   C ++ G C    ++ S ++   +  P  R      +         C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   +C+ +      A  +  SP + V+ ++C  G  C    TCC      ++CCPY   VCC+D  HCCP    C+     C +    ++
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 423          

HSP 2 Score: 195.282 bits (495), Expect = 9.273e-56
Identity = 124/356 (34.83%), Postives = 175/356 (49.16%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD--SKLKEVVTKMKLKIPAISN-LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC 1292
             T  G+ SCCP+  AV C D  HCCP+   C+ +  +C             +   +S+ ++ CPD Q +C D STCC +  GS+ CCP   AVCC D  HCCP    C+   GTC+        +++    + L  P +    V C + S C    TCC +  G + CCP   AVCCSD +HCCPQ   C +  G C   S++   + KM  +  ++S+   I C D  ++C  G TCC    GS+ CC   +AVCC D+  CCP    CN+ A +C+ +  + +P+  +       V  V C G  + C D QTCC+      + CCPY    CC+D+ HCCP    C      C
Sbjct:   75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGC-DQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVEC-GEGHFCHDNQTCCR-DNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKC 415          

HSP 3 Score: 167.933 bits (424), Expect = 1.046e-45
Identity = 106/299 (35.45%), Postives = 145/299 (48.49%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPA-----SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK----MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC--------DSKTKKPSL 1088
            V  DGS+ CCP   AVCC D  HCCP    C+  KGTC+        +++    + L  P +    V C + S C    TCC +  G + CCP   AVCCSD +HCCPQ   C +  G C  +  E+V  ++ K+PA     S    + C   + C  G TCC   GGS+ACC    AVCC D++HCCP    CN+ A +C+   KEVV+        + P +    +EC +G   C    TCC  +   + CCP+   VCC+D+  CCP    C      C        D+  + P+L
Sbjct:  141 VMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC-QRGSEIVAGLE-KMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCE---KEVVSAQPATFLARSPHVGVKDVECGEG-HFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRDPAL 432          

HSP 4 Score: 167.548 bits (423), Expect = 1.537e-45
Identity = 105/313 (33.55%), Postives = 149/313 (47.60%), Query Frame = 3
Query:  636 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFP 1535
            K     S  L   C   + C+ G +C     G+ +CCP+  AV C D  HCCP+   C+ D  +C  +               S  +I+CPD    C   +TCC++ DGS+GCCP   AVCC D + CCP    C+   GTC+    +   + K         P  + R +       C    TCC+L +G+ +GCCP   A CCSD  HCCPQ   C + +G C   +E +  ++  P    S+  P    C Q        TCCPS   S++CC  P+AVCC D  HCCP   +C++  +SC+K ++   P
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNN-----------SVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQP 347          
BLAST of Granulin b vs. Ensembl Human
Match: GRN (granulin precursor [Source:HGNC Symbol;Acc:HGNC:4601])

HSP 1 Score: 75.485 bits (184), Expect = 4.012e-15
Identity = 47/151 (31.13%), Postives = 66/151 (43.71%), Query Frame = 3
Query:  636 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSS--------------AVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNL 1046
            K     S  L   C   + C+ G +C     G+ +CCP+                AV C D  HCCP+   C+ D  +C  +               S  +I+CPD    C   +TCC++ DGS+GCCP   A CC D++ CCP    C+L
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGNN-----------SVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187          

HSP 2 Score: 74.7146 bits (182), Expect = 8.545e-15
Identity = 48/151 (31.79%), Postives = 67/151 (44.37%), Query Frame = 3
Query:  408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSS--------------AVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNL 815
            K     S  L   C   + C+ G +C     G+ +CCP+                AV C D  HCCP+   C+ D  +C  +              +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187          

HSP 3 Score: 68.9366 bits (167), Expect = 6.998e-13
Identity = 41/134 (30.60%), Postives = 61/134 (45.52%), Query Frame = 3
Query:  918 STCKTGATCCLLSDGSYGCCPFS--------------NAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNI 1277
            + C  G +C     G+  CCPF                AV C D   CCP+   C+    +C  ++            N V  + CP ++++C D  TCC +  G S+GCCP   A+CC D++HCCP    C++
Sbjct:   65 AHCSAGHSCIFTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGN----------NSVGAIQCPDSQFECPDFSTCCVMVDG-SWGCCPMPQASCCEDRVHCCPHGAFCDL 187          

HSP 4 Score: 68.9366 bits (167), Expect = 7.133e-13
Identity = 42/124 (33.87%), Postives = 58/124 (46.77%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSS--------------AVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNL 587
             T  G+ SCCP+                AV C D  HCCP+   C+ +  +C             +   +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L
Sbjct:   75 FTVSGTSSCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187          

HSP 5 Score: 55.0694 bits (131), Expect = 3.644e-8
Identity = 41/130 (31.54%), Postives = 56/130 (43.08%), Query Frame = 3
Query: 1149 QCSDGQTCCKLPAGDSYGCCPYSA--------------ATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSL 1493
             CS G +C    +G S  CCP+                A  C D  HCCP+   C+ +  +C  ++           V +I+CP+    C    TCC   + S+ CCP P A CC D  HCCP+   C L
Sbjct:   66 HCSAGHSCIFTVSGTS-SCCPFPEIKGPCQCRFLCVPQAVACGDGHHCCPRGFHCSADGRSCFQRSGNNS-------VGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDL 187          
BLAST of Granulin b vs. Ensembl Celegans
Match: pgrn-1 (ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:Q7JKP2])

HSP 1 Score: 110.538 bits (275), Expect = 2.853e-26
Identity = 83/268 (30.97%), Postives = 119/268 (44.40%), Query Frame = 3
Query:  633 MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVC-------------NLSAGTCDSKTKKPSLLI---------------KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSY---GCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKI 1325
            + L V    + +  C  +++C+D  TCC +   ++ CCP  +AVCC D+ HCCP  T C+     C    ++ V  MK K PA   +       + CPD +S C  G+TCCLL  GSYGCCP  NAVCC+D L CCP    C             +L      S  +KP++                      + V+ + C G    C    TCC +   +      CCP S A CC +   CCP    C ++ G C+  A+ +  + 
Sbjct:   84 LFLAVFLCRVTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVP-MKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIAC-GVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICCENT--CCPAGYHC-VDGGKCEKHAKTMRTRF 346          

HSP 2 Score: 109.768 bits (273), Expect = 4.507e-26
Identity = 88/263 (33.46%), Postives = 121/263 (46.01%), Query Frame = 3
Query:  405 IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSIL------SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDA----GTCDSKLKEVVTKMKLKIPAISNLS-----------------------IECPDGSSTCKTGATCCLLSDGSYG-----CCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTK 1076
            + L V    + +  C  +++C+D  TCC +   ++ CCP  +AVCC D+ HCCP  T C+     C    ++ V  MK K PA   +       VVCPD+ S+C DGSTCC +  GSY CCP  +AVCC+D  HCCP    C+             L++  +    + PA+  LS                       I C  G  TC    TCC +  G  G     CCP SNA+CC +  +CCP    C +  G C+   K
Sbjct:   84 LFLAVFLCRVTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVP-MKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVG-KTCPAKTTCCNVR-GKNGEPKTMCCPLSNAICCEN--TCCPAGYHC-VDGGKCEKHAK 340          

HSP 3 Score: 108.997 bits (271), Expect = 1.032e-25
Identity = 84/246 (34.15%), Postives = 107/246 (43.50%), Query Frame = 3
Query:  909 DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS--------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCN-------------INK--GTCDHQAEALEIKISPIL----------------VESIKCPNGSLCGQKGTCC----PSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            D  + C    TCC L D ++GCCP  NAVCC D+  CCP  T C+     C          K KKP+   KT + N  N V+CP    +C DG TCC L  G SYGCCP   A CC+D +HCCP    C+             + K   T  H+  A+E                       V+ I C  G  C  K TCC     +      CCP  NA+CC +   CCP    C ++   C+K+
Sbjct:   99 DAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPAR--KTVERNQFNEVVCPDKASKCPDGSTCCLLEQG-SYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICCEN--TCCPAGYHC-VDGGKCEKH 338          

HSP 4 Score: 101.293 bits (251), Expect = 3.833e-23
Identity = 77/235 (32.77%), Postives = 104/235 (44.26%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLK-----VPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCP-----QNTVCNLDAGTCDSKLKEVVTKMKLK----------------------VPASSILSVVCPDQSQCNDGSTCCAVAGGS----YACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKM 863
            D ++ CCP  +AVCC D+ HCCP  T C+     C    ++ V   K K     V  +    VVCPD+ S+C DGSTCC +  GSY CCP  +AVCC+D  HCCP         C+ +        K   T +  K                       P S +  + C     C   +TCC V G +      CCP S+A+CC +   CCP    C +D G C+   K + T+ 
Sbjct:  115 DNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCHGQFCSQNFAMIPHLRKFASTSIHRKPAVEFLSEEEEDDDDEESTSSEDPESDVDPIACGVGKTCPAKTTCCNVRGKNGEPKTMCCPLSNAICCENT--CCPAGYHC-VDGGKCEKHAKTMRTRF 346          

HSP 5 Score: 85.8853 bits (211), Expect = 5.835e-18
Identity = 57/152 (37.50%), Postives = 77/152 (50.66%), Query Frame = 3
Query: 1140 AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIK------ISPILVESIKCPN-GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFH 1550
            A+ +CSD +TCCKL   +++GCCP   A CC D+ HCCP  T C+     C   D +   ++ K      +       + CP+  S C    TCC     SY CCP PNAVCC+D  HCCPN  +C  + + C +N      L KF   + H
Sbjct:  100 AETECSDDETCCKL-GDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC--HGQFCSQNFAMIPHLRKFASTSIH 248          

HSP 6 Score: 51.2174 bits (121), Expect = 1.128e-6
Identity = 24/57 (42.11%), Postives = 32/57 (56.14%), Query Frame = 3
Query: 1338 VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508
            V + +C   + C    TCC   ++++ CCP PNAVCC D SHCCP  T+C      C
Sbjct:   93 VTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARC 149          
BLAST of Granulin b vs. Ensembl Celegans
Match: pgrn-1 (ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:Q7JKP2])

HSP 1 Score: 105.916 bits (263), Expect = 8.753e-25
Identity = 56/129 (43.41%), Postives = 72/129 (55.81%), Query Frame = 3
Query:  675 CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCN 1043
            C  +++C+D  TCC +   ++ CCP  +AVCC D+ HCCP  T C+     C     E    MK K PA   +       + CPD +S C  G+TCCLL  GSYGCCP  NAVCC+D L CCP    C+
Sbjct:   98 CDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGA-DEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCH 225          

HSP 2 Score: 103.219 bits (256), Expect = 6.652e-24
Identity = 57/130 (43.85%), Postives = 69/130 (53.08%), Query Frame = 3
Query:  909 DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS--------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCN 1274
            D  + C    TCC L D ++GCCP  NAVCC D+  CCP  T C+     C          K KKP+   KT + N  N V+CP    +C DG TCC L  G SYGCCP   A CC+D +HCCP    C+
Sbjct:   99 DAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPAR--KTVERNQFNEVVCPDKASKCPDGSTCCLLEQG-SYGCCPVPNAVCCADMLHCCPNGFTCH 225          

HSP 3 Score: 102.449 bits (254), Expect = 1.326e-23
Identity = 56/129 (43.41%), Postives = 73/129 (56.59%), Query Frame = 3
Query:  447 CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSIL------SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCN 812
            C  +++C+D  TCC +   ++ CCP  +AVCC D+ HCCP  T C+     C     E    MK K PA   +       VVCPD+ S+C DGSTCC +  GSY CCP  +AVCC+D  HCCP    C+
Sbjct:   98 CDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGA-DEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCH 225          

HSP 4 Score: 88.9669 bits (219), Expect = 4.329e-19
Identity = 50/112 (44.64%), Postives = 63/112 (56.25%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSIL------SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCN 584
            D ++ CCP  +AVCC D+ HCCP  T C+     C     E    +K K PA   +       VVCPD+ S+C DGSTCC +  GSY CCP  +AVCC+D  HCCP    C+
Sbjct:  115 DNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGA-DEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTCH 225          

HSP 5 Score: 86.6557 bits (213), Expect = 3.024e-18
Identity = 57/152 (37.50%), Postives = 77/152 (50.66%), Query Frame = 3
Query: 1140 AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIK------ISPILVESIKCPN-GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFH 1550
            A+ +CSD +TCCKL   +++GCCP   A CC D+ HCCP  T C+     C   D +   ++ K      +       + CP+  S C    TCC     SY CCP PNAVCC+D  HCCPN  +C  + + C +N      L KF   + H
Sbjct:  100 AETECSDDETCCKL-GDNTWGCCPMPNAVCCDDRSHCCPTGTTCDPQGARCIGADEKHVPMKKKKPARKTVERNQFNEVVCPDKASKCPDGSTCCLLEQGSYGCCPVPNAVCCADMLHCCPNGFTC--HGQFCSQNFAMIPHLRKFASTSIH 248          

HSP 6 Score: 51.2174 bits (121), Expect = 1.043e-6
Identity = 23/50 (46.00%), Postives = 31/50 (62.00%), Query Frame = 3
Query: 1338 VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            V + +C   + C    TCC   ++++ CCP PNAVCC D SHCCP  T+C
Sbjct:   93 VTAHQCDAETECSDDETCCKLGDNTWGCCPMPNAVCCDDRSHCCPTGTTC 142          
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grnb (granulin b [Source:ZFIN;Acc:ZDB-GENE-030131-7393])

HSP 1 Score: 280.796 bits (717), Expect = 2.026e-85
Identity = 179/473 (37.84%), Postives = 252/473 (53.28%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--------------DSKLKEVVTKMKLKVPAS--SILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-----IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD-------SKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            +T  G Y CCP   A CCSD  HCC Q T C+L    C   + + + V K++ K+ A     VVCPD +S+C D +TCC +  G + CCP  +AVCC D++HCCPQ T C+L    C              D++ ++ + K  + +PA   +I  V+CPD+ S+C + +TCC +  GSY CCP   AVCCSD++HCCP+ T C+L   TC S     V++M  KIPA++ L      + C + +  C +G TCC   +GS+ CCP   AVCC D + CCP+ T+CN++A +CD       S      +  K   P P  +         C    TCCKL +GD +GCCP   A CC D +HCCP  +VCN+   TC+  +++  ++IS  +V+ I           C   S C    TCC   + S++CCP P AVCC+D  HCCP   +C L   SC ++ L         P
Sbjct:   36 LTPSGGYGCCPLPHAECCSDHLHCCYQGTLCDLEHSKCVNKTHVLDWVEKVEAKLQA-----VVCPDGESECPDDTTCCQMPDGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYGSSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLS--ANGVSEMATKIPAVTVLKPKEEVVPC-NETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPAGLSVSVPWMEKVSTKPIAPPPNKKC---DESSSCPGESTCCKLSSGD-WGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDS-GLRISVPMVKKIPAVSVPSQKQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAWFRKEP 495          

HSP 2 Score: 271.937 bits (694), Expect = 5.207e-82
Identity = 173/463 (37.37%), Postives = 245/463 (52.92%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--------------DSVLKEVVTKIKLKVPAS--SILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS---IECP-----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA--EALEIKISPILVESIKCPNGSLCGQKGTCCPSAN--------DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI 1520
            DG + CCP  +AVCC D++HCCPQ T C+L    C              D+  ++ + K  + +PA   +I  V+CPD+ S+C + +TCC +  GSY CCP   AVCCSD++HCCP+ T C+L   TC S     V++M  K+PA ++L      V C +   C+ G+TCC    GS+ACCP   AVCC D  HCCP+ T+CN+ A +CD         + + +P +  +S   I  P     D SS+C   +TCC LS G +GCCP   AVCC D + CCP  +VCN++A TC++ +    L I       +  V  P  K  C +      G TCCKL +G S+ CCP   A CC+D+ HCCPQ   C++ + +C           +  P L E+ +  +  +C  + T CP  +          + CCP P AVCC D  HCCP+  +C+    SC K +
Sbjct:  113 DGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYGSSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLS--ANGVSEMATKIPAVTVLKPKEEVVPCNETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDP-----AGLSVSVPWMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDS-GLRISVPMVKKIPAVSVPSQKQNCDETSSCPTGTTCCKLTSG-SWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAWFRKEPALRETQRVEDRHMCDAQ-TSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSCTKGL 565          

HSP 3 Score: 265.003 bits (676), Expect = 2.069e-79
Identity = 173/445 (38.88%), Postives = 233/445 (52.36%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK----VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----DSKLKEVVTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQP------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV--------ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514
            GSY CCP   AVCCSD++HCCP+ T C+L   TC S     V+++  K+PA ++L      V C +   C+ G+TCC    GS+ACCP   AVCC D  HCCP+ T+CN+ A +CD      V+   ++     P +   +  C + S C   STCC ++ G + CCP   AVCC D  HCCP  +VCN+ A TC    DS L+  V  +K KIPA+S  S +   D +S+C TG TCC L+ GS+ CCP   AVCC+D+  CCPQ   C+L+  +C  ++  PS+     +P         +R +C  A+  C    TCC +     +GCCP   A CC D  HCCP    CN  K +C    HQ      K + +          E +KC + + C    TCC      + CCP   AVCC DH HCCP    C L   +C+K
Sbjct:  207 GSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLSA--NGVSEMATKIPAVTVLKPKEEVVPCNETVACSSGTTCCKTPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPAGLSVSVPWMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVPMVK-KIPAVSVPSQKQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSC-VRSGLPSMAWFRKEPALRETQRVEDRHMC-DAQTSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSCTKGLHQIPWFTKKTARVWKSSDELLGHEDVKCDSSTSCPSGSTCCILPTGQWGCCPLVKAVCCEDHEHCCPQGYICKLELGTCEK 646          

HSP 4 Score: 258.07 bits (658), Expect = 8.332e-77
Identity = 158/413 (38.26%), Postives = 219/413 (53.03%), Query Frame = 3
Query:  438 SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--------------DSKLKEVVTKMKLKIPAISN--LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-------DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI-----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC----DKNILLKFPIINFHP 1553
            +++CPD   C DG+TCC    G Y CCP   A CCSD  HCC Q T+C+L+   C +K  + + V K++ K+ A     VVCPD +S+C D +TCC +  G + CCP  +AVCC D++HCCPQ T C+L    C              D++ ++ + K  + +PA  N    + CPD  S C    TCCLL  GSYGCCP   AVCCSD+  CCP+ T C+L   TC       +  TK P++ +      P   V+       CS G TCCK P G S+ CCP   A CC D IHCCP+ T+CN+   +CD  A    + +S   +E +           KC   S C  + TCC  ++  + CCP P AVCC DH HCCP+ + C++  ++C    D  + +  P++   P
Sbjct:   19 ALICPDGGMCEDGNTCCLTPSGGYGCCPLPHAECCSDHLHCCYQGTLCDLEHSKCVNKTHVLDWVEKVEAKLQA-----VVCPDGESECPDDTTCCQMPDGGWGCCPMKNAVCCDDRKHCCPQGTTCDLVHSMCVSTTYGSSPFLRKFDARRRKPLEKNAVDLPAEVNNIREVICPDKISKCPEDTTCCLLETGSYGCCPMPKAVCCSDQKHCCPEGTTCDLIHSTCLSANGVSEMATKIPAVTVL----KPKEEVVPCNETVACSSGTTCCKTPEG-SWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPA---GLSVSVPWMEKVSTKPIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVPMVKKIP 418          

HSP 5 Score: 254.988 bits (650), Expect = 1.217e-75
Identity = 160/439 (36.45%), Postives = 223/439 (50.80%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD-----SVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----DSKLKEVVTKMKLKVPASSILSVV--CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---DGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-------TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514
            T +GS++CCP   AVCC D  HCCP+ T CN+   +CD     SV    + K+  K P +   +  C + S C   STCC ++ G + CCP   AVCC D  HCCP  +VCN+ A TC    DS L+  V  +K K+PA S+ S    C + S C  G+TCC +  GS+ACCP   AVCC+D+ HCCPQ   C+L   +C       +   + +        +E     D  ++C    TCC ++  G +GCCP   AVCC D   CCP    CN    +C          TKK + + K+      +  +   +   C  G TCC LP G  +GCCP   A CC D  HCCPQ  +C +  GTC+  +  + + ++ + +  I+C   + C    +CC  A+ +++CCPY  AVCC D  HCCP    C    + C K
Sbjct:  283 TPEGSWACCPLPKAVCCEDHIHCCPEGTLCNVAASSCDDPAGLSVSVPWMEKVSTK-PIAPPPNKKCDESSSCPGESTCCKLSSGDWGCCPLPEAVCCEDHVHCCPHGSVCNVAAETCETVSDSGLRISVPMVK-KIPAVSVPSQKQNCDETSSCPTGTTCCKLTSGSWACCPMPQAVCCADQEHCCPQGYTCDLAQSSCVRSGLPSMAWFRKEPALRETQRVEDRHMCDAQTSCPRDDTCCFINRIGKWGCCPLPKAVCCKDGDHCCPSGYTCNEEKTSCTKGLHQIPWFTKKTARVWKSSDELLGHEDVKCDSSTSCPSGSTCCILPTG-QWGCCPLVKAVCCEDHEHCCPQGYICKLELGTCEKASADVSVSLTAVQMPEIQCDTFTRCAHTQSCCRLADSTWACCPYTQAVCCKDMKHCCPMGYKCDPKVQGCTK 718          
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 265.388 bits (677), Expect = 1.615e-78
Identity = 177/476 (37.18%), Postives = 243/476 (51.05%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEV----VTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            T DG ++CCP   AVCC D  HCCP   +C++  G+C+      S +++V    + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ +  +S +S  I C D +  C  G+TCC   DG +GCCP   AVCC D + CCP    CN++AG+CD  +      +K  + ++  Q  P  +V C  A + C +  TCCK  AG+ +GCCP+S A CC+D  HCCP +  CN++  +C         +   A E   +P L +  +KC   S C    TCC  + D   CCP+P AVCC D  HCCP    C L  +SC K   L   I   
Sbjct:  306 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACND-TVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQ-RPSGKVKC-NATHGCPESSTCCKNIAGE-WGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQL 777          

HSP 2 Score: 241.891 bits (616), Expect = 6.192e-70
Identity = 168/511 (32.88%), Postives = 240/511 (46.97%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS--------------VLKEVVTKIKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLKIPAISNL------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT--------------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVESIKCPNGSL-------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544
            DG + CCP   AVCC DK HCCP++T C++    C S               L+      K K P +   +                             V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++     N+       + C D ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C+  +              +K  + + T   +PV+  I       C DG TCCK   G+ +GCCP   A CC D IHCCP    CN+  G+CD  + ++  ++  P+ + + + P+G +       C +  TCC +    + CCP+  AVCC+D  HCCP +  C+L++ SC K  ++  P  N
Sbjct:  189 DGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTV--SPVSSDIACNDTVACPDGSTCCKDKDGE-WGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVV-IPWYN 694          

HSP 3 Score: 234.187 bits (596), Expect = 4.410e-67
Identity = 165/483 (34.16%), Postives = 232/483 (48.03%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC---DSKTKKPSLLIKTFQPNP---VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISP------------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFVFT 1583
            T +G ++CCP   AVCC D  HCCP+  +CN+    C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ V   S +S  + C D   C DGSTCC    G + CCP   AVCC D  HCCP    CN+ AG+CD     V  V K+ + + A    S  ++C + +  C   +TCC    G +GCCPFS AVCC+D   CCP +  CNLS+ +C   D      + +     P P   +  V C   +  CS   TCC L + D  GCCP+  A CC D+ HCCP+   C++ + +C  +   L ++I+             ++V+ ++C  G  C    TCC ++  ++ CCP P AVCC D  HCCP    C           L     +N+   F+      T
Sbjct:  394 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKC-NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKC-DEQSSCSADSTCCLL-SKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSC-VKTTRLYVEITQLTHIRSNKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPGGTCISAGDLDWSNWVNWKLFFSKKKRALT 872          

HSP 4 Score: 226.483 bits (576), Expect = 2.578e-64
Identity = 157/495 (31.72%), Postives = 221/495 (44.65%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGA------------KYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE------------SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            SY CCP +  + CSD +HCCP + EC+ +   C          +K KV    + +V+C +  S+C   +TCC    G + CCP   AVCC DK HCCP++TVC++ A  C S              +L+      K K P +   +                             V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ +  +S++S + P + ++ C  G TCC   +G + CCP   AVCC D + CCP+   CN++A  C+        L+K     PV     P                 C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+  + ++    ++ + PI  +             I C +   C    TCC   +  + CCP P AVCC D  HCCP+   C++   SCD
Sbjct:  127 SYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC----------VKRKV---KVQTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQ---TPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 604          

HSP 5 Score: 206.068 bits (523), Expect = 5.913e-57
Identity = 152/495 (30.71%), Postives = 215/495 (43.43%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-----LKEVVTKIKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKIPAISNLS-----------------------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPN-------------GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            G +SCCP+    CC D  HCCP+   C++   TC +      L +     K  +P S  +    P       C DGS+C     C +   SY CCP +  + CSD +HCCP +  C+ D+  C         K K+KV      +V+C +  S+C   +TCC    G + CCP   AVCC DK HCCP++TVC++ A  C S              +L+      K K P     +                             + C D ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C+  +   S +            +   Q + V+  +       C+DG TCCK   GD + CCP   A CC D +HCCP+   CNI    C+      E  +    V+S   PN              + C    TCC + +  ++CCP P AVCC D  HCCP+   C +   SC+
Sbjct:   37 GGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGD-WACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCE 516          

HSP 6 Score: 196.052 bits (497), Expect = 1.657e-53
Identity = 135/458 (29.48%), Postives = 204/458 (44.54%), Query Frame = 3
Query:  405 IKLKVPASSILSVVC---PDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----LKEVVTKMKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-----------------------DSKTKKPSLLIKTFQP-------NPVNRVICPGAKYQ-------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            ++L V  + +  V+C   P+   C  G +CC    G ++CCP+    CC D  HCCP+  +C++   TC +      L +     K  +P S  +    P       C DGS+C     C +   SY CCP +  + CSD +HCCP +  C+ D+  C         K K+K+      ++ C +G+S C    TCC   DG +GCCP   AVCC DK+ CCP++TVC++ A  C                       D K K+P     T +P          N++    A++Q             C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+  + ++    ++ + PI  + +             C + + C    TCC +    ++CCP P AVCC D  HCCP    C++    C+  +  + P++   P
Sbjct:    2 LRLTVCLAVVTLVICSQCPNNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 445          
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 265.388 bits (677), Expect = 1.807e-78
Identity = 174/475 (36.63%), Postives = 242/475 (50.95%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEV----VTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            T DG ++CCP   AVCC D  HCCP   +C++  G+C+      S +++V    + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ +   S+ S + P + ++ C  G+TCC   DG + CCP   AVCC D + CCP    CN++AG+CD  +      +K  + ++  Q  P  +V C  A + C +  TCCK  AG+ +GCCP+S A CC+D  HCCP +  CN++  +C         +   A E   +P L +  +KC   S C    TCC  + D   CCP+P AVCC D  HCCP    C L  +SC K   L   I   
Sbjct:  306 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQ-RPSGKVKC-NATHGCPESSTCCKNIAGE-WGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQL 777          

HSP 2 Score: 237.269 bits (604), Expect = 3.477e-68
Identity = 165/486 (33.95%), Postives = 232/486 (47.74%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICP---------GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISP------------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFVFT 1583
            T +G ++CCP   AVCC D  HCCP+  +CN+    C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ V  +S  S  V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    CN+ AG+CD     V  V K+ + + A    S  ++C + +  C   +TCC    G +GCCPFS AVCC+D   CCP +  CNLS+ +C     K  ++I  +          P           +  CS   TCC L + D  GCCP+  A CC D+ HCCP+   C++ + +C  +   L ++I+             ++V+ ++C  G  C    TCC ++  ++ CCP P AVCC D  HCCP    C           L     +N+   F+      T
Sbjct:  394 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKC-NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSC----IKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLL-SKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSC-VKTTRLYVEITQLTHIRSNKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPGGTCISAGDLDWSNWVNWKLFFSKKKRALT 872          

HSP 3 Score: 237.269 bits (604), Expect = 4.002e-68
Identity = 166/509 (32.61%), Postives = 235/509 (46.17%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS--------------VLKEVVTKIKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLKIPAISNL------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-FQPNPVNRVICPGAK-----------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVESIKCPNGSL-------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544
            DG + CCP   AVCC DK HCCP++T C++    C S               L+      K K P +   +                             V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++     N+       + C D ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C+  +     + K   +P    +V    A              C DG TCCK   G  + CCP   A CC D IHCCP    CN+  G+CD  + ++  ++  P+ + + + P+G +       C +  TCC +    + CCP+  AVCC+D  HCCP +  C+L++ SC K  ++  P  N
Sbjct:  189 DGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVV-IPWYN 694          

HSP 4 Score: 227.639 bits (579), Expect = 1.040e-64
Identity = 156/495 (31.52%), Postives = 224/495 (45.25%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGA------------KYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            SY CCP +  + CSD +HCCP + EC+ +   C          +K KV    + +V+C +  S+C   +TCC    G + CCP   AVCC DK HCCP++TVC++ A  C S              +L+      K K P +   +                             V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ +  +S++S + P + ++ C  G TCC   +G + CCP   AVCC D + CCP+   CN++A  C+        L+K     PV     P                 C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+  + ++    ++ + PI  + +             C + + C    TCC + +  ++CCP P AVCC D  HCCP+   C++   SCD
Sbjct:  127 SYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC----------VKRKV---KVQTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQ---TPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 604          

HSP 5 Score: 205.682 bits (522), Expect = 6.030e-57
Identity = 152/495 (30.71%), Postives = 215/495 (43.43%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-----LKEVVTKIKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKIPAISNLS-----------------------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPN-------------GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            G +SCCP+    CC D  HCCP+   C++   TC +      L +     K  +P S  +    P       C DGS+C     C +   SY CCP +  + CSD +HCCP +  C+ D+  C         K K+KV      +V+C +  S+C   +TCC    G + CCP   AVCC DK HCCP++TVC++ A  C S              +L+      K K P     +                             + C D ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C+  +   S +            +   Q + V+  +       C+DG TCCK   GD + CCP   A CC D +HCCP+   CNI    C+      E  +    V+S   PN              + C    TCC + +  ++CCP P AVCC D  HCCP+   C +   SC+
Sbjct:   37 GGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGD-WACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCE 516          

HSP 6 Score: 196.052 bits (497), Expect = 1.657e-53
Identity = 135/458 (29.48%), Postives = 204/458 (44.54%), Query Frame = 3
Query:  405 IKLKVPASSILSVVC---PDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----LKEVVTKMKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-----------------------DSKTKKPSLLIKTFQP-------NPVNRVICPGAKYQ-------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            ++L V  + +  V+C   P+   C  G +CC    G ++CCP+    CC D  HCCP+  +C++   TC +      L +     K  +P S  +    P       C DGS+C     C +   SY CCP +  + CSD +HCCP +  C+ D+  C         K K+K+      ++ C +G+S C    TCC   DG +GCCP   AVCC DK+ CCP++TVC++ A  C                       D K K+P     T +P          N++    A++Q             C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+  + ++    ++ + PI  + +             C + + C    TCC +    ++CCP P AVCC D  HCCP    C++    C+  +  + P++   P
Sbjct:    2 LRLTVCLAVVTLVICSQCPNNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 445          
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 266.544 bits (680), Expect = 5.462e-78
Identity = 179/485 (36.91%), Postives = 235/485 (48.45%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-------VLKEVVTKIKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS------------------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            T DG ++CCP   AVCC D  HCCP   +C++  G+C+        V K  V  I+ +  A + +S     + C D   C DGSTCC    G + CCP   AVCC D  HCCP    CN+ AG+CD     V          + K K+ V  +S  S  V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V    K+ +  I                   N ++ CPDGS       TCC   DG +GCCP   AVCC D + CCP    CN++AG+CD  +      +K  + ++  Q  P  +V C  A + C +  TCCK  AG+ +GCCP+S A CC+D  HCCP +  CN++  +C         +   A E   +P L +  +KC   S C    TCC  + D   CCP+P AVCC D  HCCP    C L  +SC K   L   I   
Sbjct:  479 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGS-------TCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQ-RPSGKVKC-NATHGCPESSTCCKNIAGE-WGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQL 953          

HSP 2 Score: 259.996 bits (663), Expect = 1.530e-75
Identity = 169/479 (35.28%), Postives = 240/479 (50.10%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQP-----------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVESIKCPNGSL-------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544
            T +G ++CCP   AVCC D  HCCP+  +CN+    C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ V   S +S  + C D   C DGSTCC    G + CCP   AVCC D  HCCP    CN+ AG+CD     V          + K K+ +   S+ S + P + ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C DS    P +     +P           +PV+  +       C DG TCCK   GD +GCCP   A CC D IHCCP    CN+  G+CD  + ++  ++  P+ + + + P+G +       C +  TCC +    + CCP+  AVCC+D  HCCP +  C+L++ SC K  ++  P  N
Sbjct:  394 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGSTCCKDKDGD-WGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVV-IPWYN 870          

HSP 3 Score: 251.521 bits (641), Expect = 1.399e-72
Identity = 170/483 (35.20%), Postives = 235/483 (48.65%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEV----VTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-FQPNPVNRVICPGAK-----------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD-----------------HQAEALEIKISPILV-----ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            T DG ++CCP   AVCC D  HCCP   +C++  G+C+      S +++V    + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ +  +S +S  I C D +  C  G+TCC   DG +GCCP   AVCC D + CCP    CN++AG+CD  +     + K   +P    +V    A              C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+                  + +    K+SP+       +++ CP+GS      TCC   +  + CCP P AVCC D  HCCP+   C++   SCD
Sbjct:  306 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACND-TVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGS------TCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 780          

HSP 4 Score: 238.424 bits (607), Expect = 7.320e-68
Identity = 165/510 (32.35%), Postives = 233/510 (45.69%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS--------------VLKEVVTKIKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLKIPAISNL------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT--------------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            DG + CCP   AVCC DK HCCP++T C++    C S               L+      K K P +   +                             V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++     N+       + C D ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C+  +              +K  + + T   +PV+  I       C DG TCCK   G+ +GCCP   A CC D IHCCP    CN+  G+CD  + ++    ++ + PI  + +             C + + C    TCC + +  ++CCP P AVCC D  HCCP+   C +   SC+ +
Sbjct:  189 DGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTV--SPVSSDIACNDTVACPDGSTCCKDKDGE-WGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDS 694          

HSP 5 Score: 237.269 bits (604), Expect = 1.718e-67
Identity = 171/486 (35.19%), Postives = 229/486 (47.12%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS----------VLKEVVTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKV--------------PASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC---DSKTKKPSLLIKTFQPNP---VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISP------------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFVFT 1583
            DG + CCP   AVCC D  HCCP   +CN+  G+CD           V    + K K+ V  +S  S  V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V    K+ V              P SS   V C D   C DGSTCC    G + CCP   AVCC D  HCCP    CN+ AG+CD     V  V K+ + + A    S  ++C + +  C   +TCC    G +GCCPFS AVCC+D   CCP +  CNLS+ +C   D      + +     P P   +  V C   +  CS   TCC L + D  GCCP+  A CC D+ HCCP+   C++ + +C  +   L ++I+             ++V+ ++C  G  C    TCC ++  ++ CCP P AVCC D  HCCP    C           L     +N+   F+      T
Sbjct:  569 DGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSS--DVACNDTVACPDGSTCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKC-NATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKGDVVIPWYNKIAAESTPAPKLDLGVVKC-DEQSSCSADSTCCLL-SKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSC-VKTTRLYVEITQLTHIRSNKPQPSVVVKDVQCGGGFSCHDGETCCLTSQTTWGCCPSPKAVCCDDMQHCCPAGYKCGPGGTCISAGDLDWSNWVNWKLFFSKKKRALT 1048          

HSP 6 Score: 226.483 bits (576), Expect = 1.185e-63
Identity = 157/495 (31.72%), Postives = 221/495 (44.65%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKVPASSILS-----------------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGA------------KYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE------------SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            SY CCP +  + CSD +HCCP + EC+ +   C          +K KV    + +V+C +  S+C   +TCC    G + CCP   AVCC DK HCCP++TVC++ A  C S              +L+      K K P +   +                             V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    C++ AG+C+     V          + K K+ +  +S++S + P + ++ C  G TCC   +G + CCP   AVCC D + CCP+   CN++A  C+        L+K     PV     P                 C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+  + ++    ++ + PI  +             I C +   C    TCC   +  + CCP P AVCC D  HCCP+   C++   SCD
Sbjct:  127 SYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC----------VKRKV---KVQTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQ---TPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVPWVEKVPVRPIRKQKVAVTTVSPVSSDIACNDTVACPDGSTCCKDKDGEWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 604          

HSP 7 Score: 205.682 bits (522), Expect = 2.038e-56
Identity = 152/495 (30.71%), Postives = 215/495 (43.43%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-----LKEVVTKIKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS--------------KLKEVVTKMKLKIPAISNLS-----------------------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPN-------------GSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            G +SCCP+    CC D  HCCP+   C++   TC +      L +     K  +P S  +    P       C DGS+C     C +   SY CCP +  + CSD +HCCP +  C+ D+  C         K K+KV      +V+C +  S+C   +TCC    G + CCP   AVCC DK HCCP++TVC++ A  C S              +L+      K K P     +                             + C D ++ C  G+TCC   DG + CCP   AVCC D + CCP    C+++AG+C+  +   S +            +   Q + V+  +       C+DG TCCK   GD + CCP   A CC D +HCCP+   CNI    C+      E  +    V+S   PN              + C    TCC + +  ++CCP P AVCC D  HCCP+   C +   SC+
Sbjct:   37 GGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACND-TAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGD-WACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCE 516          

HSP 8 Score: 201.06 bits (510), Expect = 7.444e-55
Identity = 149/415 (35.90%), Postives = 196/415 (47.23%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-------VLKEVVTKIKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV--VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL-----IKTFQPNP---VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYS 1418
            T DG ++CCP   AVCC D  HCCP   +C++  G+C+        V K  V  I+ +  A++ +S     V C D   C DGSTCC    G + CCP   AVCC D  HCCP    CN+ AG+CD     V  V K+ + + A    S  V C     C + STCC    G + CCP+S AVCC+D  HCCP +  CNL + +C     +VV     KI A S      +L +   D  S+C   +TCCLLS    GCCPF  AVCC D+  CCP+   C+L   +C   T+    +     I++ +P P   V  V C G  + C DG+TCC L +  ++GCCP   A CC D  HCCP                                   G  CG  GTC  + +  +S
Sbjct:  655 TKDGGWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDSSGSVPWVEKVPVRPIRKQKVANTKVSPVSSDVACNDTVACPDGSTCCKDKDGDWGCCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWVEKVPVHLRAGQRPSGKVKCNATHGCPESSTCCKNIAGEWGCCPFSQAVCCTDGEHCCPAHYKCNLSSVSCIKG--DVVIPWYNKIAAESTPAPKLDLGVVKCDEQSSCSADSTCCLLSKDETGCCPFPEAVCCPDQKHCCPEGYRCDLRRRSCVKTTRLYVEITQLTHIRSNKPQPSVVVKDVQC-GGGFSCHDGETCC-LTSQTTWGCCPSPKAVCCDDMQHCCPA----------------------------------GYKCGPGGTCISAGDLDWS 1031          

HSP 9 Score: 195.667 bits (496), Expect = 4.599e-53
Identity = 135/458 (29.48%), Postives = 204/458 (44.54%), Query Frame = 3
Query:  405 IKLKVPASSILSVVC---PDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----LKEVVTKMKLKVPASSILSVVCPDQSQ---CNDGSTC-----CAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-----------------------DSKTKKPSLLIKTFQP-------NPVNRVICPGAKYQ-------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            ++L V  + +  V+C   P+   C  G +CC    G ++CCP+    CC D  HCCP+  +C++   TC +      L +     K  +P S  +    P       C DGS+C     C +   SY CCP +  + CSD +HCCP +  C+ D+  C         K K+K+      ++ C +G+S C    TCC   DG +GCCP   AVCC DK+ CCP++TVC++ A  C                       D K K+P     T +P          N++    A++Q             C DG TCCK   G  + CCP   A CC D IHCCP    C++  G+C+  + ++    ++ + PI  + +             C + + C    TCC +    ++CCP P AVCC D  HCCP    C++    C+  +  + P++   P
Sbjct:    2 LRLTVCLAVVTLVICSQCPNNEVCEAGQSCCQDPTGGFSCCPFHHGECCEDHLHCCPEGMLCSVKDLTCTNATHTQPLADRTLAKKPDLPKSFRMIFSMPASESDITCPDGSSCPAEFSCLLMSTSYGCCPVAQGLACSDGKHCCPNDHECSTDSSLC--------VKRKVKV-----QTVLCGNGTSECPADTTCCQADDGQWGCCPMPKAVCCDDKIHCCPEDTVCDVKALKCVSSTNQELPMWDKFPARLRAEWEDHKQKRPETQRTTARPTGTTSTTTAANQMTTLPAEHQGVSSDVACNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCDVAAGSCEDPSGSVSWVEKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 445          
BLAST of Granulin b vs. Ensembl Zebrafish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 154.066 bits (388), Expect = 2.309e-42
Identity = 96/252 (38.10%), Postives = 130/252 (51.59%), Query Frame = 3
Query:  375 DSVLKEVVTKIKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL---KEVVTKMKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD 1064
            + V    + K K+ V   S +S  V C D + C DG+TCC    G +ACCP   AVCC D  HCCP+   CN+ A  C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    CN+ AG+CD     V          + K K+ +   S+ S + P + ++ C  G+TCC   DG + CCP   AVCC D + CCP    CN++AG+CD
Sbjct:   19 EKVPVRPIRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 270          

HSP 2 Score: 140.969 bits (354), Expect = 1.405e-37
Identity = 86/211 (40.76%), Postives = 110/211 (52.13%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVL---KEVVTKIKLK------VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV----------VTKMKLKVPASSILS--VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD 833
            T +G ++CCP   AVCC D  HCCP+  +CN+    C+  L   + +V +  ++      V  +    V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    CN+ AG+CD     V          + K K+ V  +S  S  V C D + C DGSTCC    G +ACCP   AVCC D  HCCP    CN+ AG+CD
Sbjct:   60 TKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVIGTQKSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 270          

HSP 3 Score: 130.568 bits (327), Expect = 8.192e-34
Identity = 81/248 (32.66%), Postives = 122/248 (49.19%), Query Frame = 3
Query:  852 VTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSLLIKTFQPNPVNRVICPGAKYQ---------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIK------------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            + K K+ +  +S++S + P + ++ C  G TCC   +G + CCP   AVCC D + CCP+   CN++A  C+    T++P +     Q      VI  G +           C DG TCCK   G  + CCP   A CC D IHCCP    CN+  G+CD  + ++    ++ + PI  + +             C + + C    TCC + +  ++CCP P AVCC D  HCCP+   C++   SCD
Sbjct:   26 IRKQKVAVTQVSSVSSDVPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTPVQSTTTPNVI--GTQKSDVPCNDTAACPDGSTCCKTKDG-GWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCDDPSGSVPWMDKVPVRPIKKQKVAVTQASSASSDVPCNDTAACPDGSTCCKTKDGGWACCPLPEAVCCEDFIHCCPHGKKCNVAAGSCD 270          

HSP 4 Score: 51.9878 bits (123), Expect = 7.947e-7
Identity = 22/69 (31.88%), Postives = 35/69 (50.72%), Query Frame = 3
Query: 1347 IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            + C + + C    TCC +    ++CCP P AVCC D  HCCP    C++    C+  +  + P++   P
Sbjct:   43 VPCNDTAACADGTTCCKTKEGDWACCPLPEAVCCEDFVHCCPKGKKCNIAAMKCEDPLCTEEPLVKQTP 111          
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 239.965 bits (611), Expect = 1.338e-68
Identity = 154/420 (36.67%), Postives = 207/420 (49.29%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV--VTKIKLKVPASSI---------LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE--VVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVES--IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            S+ CCP   AVCC D  HCCP N+EC++ +G C S    +  ++K+  +V +  +           V C D + C DGSTCC     +Y CC   SAVCCSD  HCCP  T C+L    C S+  E  ++ +M   +   S   V C   + C D +TCC ++   + CCPY+ AVCC D  HCCP    C+   G+C      +    K     +    ++C D +++C    TCC L  G +GCCP   AVCC+D L CCP+   C  S G C           KT       R +     Y C DGQTCC+L +GD +GCCP + A CC D  HCCP    C+  +      +  L  K   +  E+  +KC +   C    TCC  A+  + CCP   AVCC DH HCCP   +CS
Sbjct:  142 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMP-AIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQC-DDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 554          

HSP 2 Score: 226.868 bits (577), Expect = 5.306e-64
Identity = 151/413 (36.56%), Postives = 203/413 (49.15%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL-KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            D +Y CC   SAVCCSD  HCCP  T C+L    C S   E     ++  +   S   V C   + C D +TCC ++   + CCPY+ AVCC D  HCCP    C+   G+C      +    K          V C D + C +  TCC +  G + CCP   AVCC+D  HCCP+   C+   G C SK++  +     K PA+++ +  +EC D  S C  G TCC L+ G +GCCP + AVCC D   CCP    C  S G C        L  KT       + +     + C+DGQTCC+L +GD +GCCP + A CC D  HCCP    C+ ++      +     K +P L    + ++C +   C    TCC  A+  + CCP   AVCC DH HCCP   +CS
Sbjct:  227 DHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFT-KTPALTHEARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 628          

HSP 3 Score: 189.889 bits (481), Expect = 5.164e-51
Identity = 134/363 (36.91%), Postives = 183/363 (50.41%), Query Frame = 3
Query:  459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---------DSKLKEVVTKMKLKIPAISN--LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            S C D  +C     G  ACCP +    C D  HCC   + C+ D   C              +PAS+  +VVCPD +S+C   +TCC ++   S+ CCP   AVCC D  HCCP N+ C++  G C          SKL   V    LK+  + +    + C DG + C  G+TCC   D +YGCC   +AVCCSD L CCP  T C+L    C S+T +  LL  +   +    N+V C  A   C D  TCC L + + +GCCPY+ A CC D IHCCP    C  + G+C   +H    +   ++  L    ++C + + C +K TCC   +  + CCP   AVCC+DH HCCP   +CS
Sbjct:   63 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPC-DATTSCPDKNTCCHL-SSEKWGCCPYAQAVCCDDHIHCCPSGFTC--SGGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS 406          

HSP 4 Score: 186.037 bits (471), Expect = 9.365e-50
Identity = 135/438 (30.82%), Postives = 174/438 (39.73%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYS-----------------------------------------------AATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCP 1427
            G + CCP   AVCC+D  HCCP+   C+  +G C  +   +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+         + E       K PA+   +  ++C D  S C  G TCC L+ G +GCCP + AVCC D   CCP    C  S G C           KT        ++     + C DG TCC++ +G  +GCCP                                                  A CCSD  HCCPQ   C+  +GTC     ++    ++   P       C +   C    TCCP     + CCP
Sbjct:  379 GKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGS----QCMIGEHSIPWFSKTPALKQKAKDVQCDDMYS-CADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPWYSKTPALKQEGNIVKCDDSFACKDGYTCCRMVSG-VWGCCPIEKCCQTHTPLLPLQKCCPSLPILALATCHVQDSVQDSCTRLQSTHWCRTAVCCSDHWHCCPQGFTCDA-RGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCP 803          

HSP 5 Score: 162.54 bits (410), Expect = 1.031e-41
Identity = 140/478 (29.29%), Postives = 178/478 (37.24%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSN-----------------------------------------------AVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDK--IHCCPQNTVCNINKGTCDH-------QAEALEIKISPILVESIK-----CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G + CCP + AVCC D +HCCP    C+   G C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+     C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C  +  E       K PA+      ++C D S  CK G TCC +  G +GCCP                                                  AVCCSD   CCPQ   C+        +   P L      P      IC    + C  G TCC    G  + CCP    +    +  I       V  ++   C         Q EA+E   S   V+ ++     C +   C    TCC      ++CC Y   VCC D  HCCP    C  +  SC ++
Sbjct:  453 GDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQC--QKGEHSIPWYSKTPALKQEGNIVKC-DDSFACKDGYTCCRMVSGVWGCCPIEKCCQTHTPLLPLQKCCPSLPILALATCHVQDSVQDSCTRLQSTHWCRTAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSIC-DDTHTCPSGTTCCPGEGG-GWRCCPVEEVSKMVKRTVILLATACIVTLVSFSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCLNHGTSCSRS 919          

HSP 6 Score: 149.443 bits (376), Expect = 2.215e-37
Identity = 110/343 (32.07%), Postives = 150/343 (43.73%), Query Frame = 3
Query:  639 LKVPASSILSVVCPDQSQCNDGSTCCAVAG----------------------------------------GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ-AEALEIKISPILVES----IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            L +  S++ + +CPD S C + S CC + G                                        G  ACCP +    C D  HCC   + C+ D   C              IPA +  ++ CPDG S C T  TCC++SD  S+GCCP   AVCC D + CCP N+ C++  G C S             + K   L +     +   RV C    + C DG TCC+     +YGCC   +A CCSD +HCCP  T C++    C  Q  E   +   P + E     + C   + C  K TCC  +++ + CCPY  AVCC DH HCCP+  +CS
Sbjct:    7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAAEVVSRSLPMILSQTSCSGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLG-DEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS 332          

HSP 7 Score: 63.5438 bits (153), Expect = 7.055e-10
Identity = 64/208 (30.77%), Postives = 83/208 (39.90%), Query Frame = 3
Query:  903 CPDGSSTCKTGATCCLL-SDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            CPDGS TC   + CC L     YGCCP +  V                            P +L +T          C G    C D  +C   P G +  CCP +    C D  HCC   + C+ +   C          I      ++ CP+G S C    TCC  ++  S+ CCP P AVCC DH HCCP+N+ C +    C  N
Sbjct:   19 CPDGS-TCGEKSLCCELPGKKGYGCCPAAEVV------------------------SRSLPMILSQTS---------CSG----CPDEYSCVNTPEGGT-ACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC----------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISN 177          
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 232.261 bits (591), Expect = 4.931e-67
Identity = 162/440 (36.82%), Postives = 214/440 (48.64%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL----KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI----LLKFPIINF 1547
            S+ CCP   AVCC D  HCCP N+EC++ +G C S    +    KL    K        V C D + C DGSTCC     +Y CC   SAVCCSD  HCCP  T C+L    C S+  E    +  ++PA    S    +Q  C+      TCC +  G + CCP   AVCC+D  HCCP+   C+   G C SK++  +     K PA+++ +  +EC D  S C  G TCC L+ G +GCCP + AVCC D   CCP    C  S G C        L  KT       + +     + C+DGQTCC+L +GD +GCCP + A CC D  HCCP    C+ ++      +     K +P L    + ++C +   C    TCC  A+  + CCP   AVCCSDH HCCP   +C               L K P + F
Sbjct:  142 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFT-KTPALTHEARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPF 567          

HSP 2 Score: 200.675 bits (509), Expect = 1.673e-55
Identity = 141/395 (35.70%), Postives = 184/395 (46.58%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCP 1427
            D +Y CC   SAVCCSD  HCCP  T C+L    C S   E    +  ++PA    S    +Q  C+      TCC +  G + CCP   AVCC+D  HCCP+   C+   G C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C  +  E    +  K PA+   +  ++C D + +C  G TCC L+ G +GCCP + AVCC D   CCP    C  S   C           KT       + +     Y C+DGQTCC+L +GD +GCCP + A CCSD  HCCPQ   C+  +GTC     ++    ++   P       C +   C    TCCP     + CCP
Sbjct:  220 DHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQC--QKGEHSIPLFSKTPALRQETKYVKC-DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGD-WGCCPIAQAVCCSDHWHCCPQGFTCDA-RGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCP 598          

HSP 3 Score: 190.274 bits (482), Expect = 8.774e-52
Identity = 139/436 (31.88%), Postives = 183/436 (41.97%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDK--IHCCPQNTVCNINKGTCDH-------QAEALEIKISPILVESIK-----CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            G + CCP   AVCC+D  HCCP+   C+  +G C  +   +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+         + E       K PA+   +  ++C D  S C  G TCC L+ G +GCCP + AVCCSD   CCPQ   C+        +   P L      P      IC    + C  G TCC    G  + CCP    +    +  I       V  ++   C         Q EA+E   S   V+ ++     C +   C    TCC      ++CC Y   VCC D  HCCP    C  +  SC ++   ++
Sbjct:  295 GKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGS----QCMIGEHSIPWFSKTPALKQKAKDVQCDDMYS-CADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSIC-DDTHTCPSGTTCCPGEGG-GWRCCPVEEVSKMVKRTVILLATACIVTLVSFSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCLNHGTSCSRSGSPRW 719          

HSP 4 Score: 183.726 bits (465), Expect = 1.757e-49
Identity = 128/356 (35.96%), Postives = 175/356 (49.16%), Query Frame = 3
Query:  459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVES---IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            S C D  +C     G  ACCP +    C D  HCC   + C+ D   C              +PAS+  +VVCPD +S+C   +TCC ++   S+ CCP   AVCC D  HCCP N+ C++  G C S    +    KL    K        + C DG + C  G+TCC   D +YGCC   +AVCCSD L CCP  T C+L    C S+T +  LL  +   +    N+V C     +    +TCC+L +G  +GCCP   A CC+D +HCCP+   C  ++G C     ++     +P L      ++C +   C    TCC  A+  + CCP   AVCC DH HCCP   +CS
Sbjct:   63 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKK----ETCCRLVSG-KWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 396          

HSP 5 Score: 153.295 bits (386), Expect = 7.202e-39
Identity = 120/369 (32.52%), Postives = 163/369 (44.17%), Query Frame = 3
Query:  411 LKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA--LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            L +  S++ + +CPD S C + S CC + G   Y CCP +                              EVV++  L +  S      CPD+  C +         G  ACCP +    C D  HCC   + C+ D   C              IPA +  ++ CPDG S C T  TCC++SD  S+GCCP   AVCC D + CCP N+ C++  G C S       + K       + +   RV C    + C DG TCC+     +YGCC   +A CCSD +HCCP  T C++    C  Q     L  ++  I  ES          +K TCC   +  + CCP   AVCC+DH HCCP   +CS
Sbjct:    7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSR-SLPMILSQTSCSGCPDEYSCVN------TPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS 322          

HSP 6 Score: 115.161 bits (287), Expect = 2.959e-26
Identity = 91/316 (28.80%), Postives = 134/316 (42.41%), Query Frame = 3
Query:  639 LKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-DHQAEALEIKISPILVES-------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFPIIN 1544
            L +  S++ + +CPD S C + S CC + G   Y CCP +                              EVV++    I + ++ S  CPD  S       C    +G   CCP +    C D   CC   + C+     C   + +             + V+CP  + +C    TCC +    S+GCCP   A CC D +HCCP N+ C++ +G C  +Q     +   P  V+S       + C +G+ C    TCC   + +Y CC   +AVCCSDH HCCP  T+C L  K C     +  +L + P I 
Sbjct:    7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSRSLPMILSQTSCS-GCPDEYS-------CVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYCIPASNQ-------------SAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIR 271          
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 231.491 bits (589), Expect = 1.295e-66
Identity = 162/440 (36.82%), Postives = 214/440 (48.64%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL----KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI----LLKFPIINF 1547
            S+ CCP   AVCC D  HCCP N+EC++ +G C S    +    KL    K        V C D + C DGSTCC     +Y CC   SAVCCSD  HCCP  T C+L    C S+  E    +  ++PA    S    +Q  C+      TCC +  G + CCP   AVCC+D  HCCP+   C+   G C SK++  +     K PA+++ +  +EC D  S C  G TCC L+ G +GCCP + AVCC D   CCP    C  S G C        L  KT       + +     + C+DGQTCC+L +GD +GCCP + A CC D  HCCP    C+ ++      +     K +P L    + ++C +   C    TCC  A+  + CCP   AVCCSDH HCCP   +C               L K P + F
Sbjct:  162 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFT-KTPALTHEARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPF 587          

HSP 2 Score: 199.904 bits (507), Expect = 3.510e-55
Identity = 141/396 (35.61%), Postives = 184/396 (46.46%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCN---DGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCP 1427
             D +Y CC   SAVCCSD  HCCP  T C+L    C S   E    +  ++PA    S    +Q  C+      TCC +  G + CCP   AVCC+D  HCCP+   C+   G C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C  +  E    +  K PA+   +  ++C D + +C  G TCC L+ G +GCCP + AVCC D   CCP    C  S   C           KT       + +     Y C+DGQTCC+L +GD +GCCP + A CCSD  HCCPQ   C+  +GTC     ++    ++   P       C +   C    TCCP     + CCP
Sbjct:  239 VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGE--GPLLPQMPAIREESA---NQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQC--QKGEHSIPLFSKTPALRQETKYVKC-DDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGD-WGCCPIAQAVCCSDHWHCCPQGFTCDA-RGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCP 618          

HSP 3 Score: 189.504 bits (480), Expect = 1.849e-51
Identity = 139/431 (32.25%), Postives = 181/431 (42.00%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS--IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDK--IHCCPQNTVCNINKGTCDH-------QAEALEIKISPILVESIK-----CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G + CCP   AVCC+D  HCCP+   C+  +G C  +   +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+         + E       K PA+   +  ++C D  S C  G TCC L+ G +GCCP + AVCCSD   CCPQ   C+        +   P L      P      IC    + C  G TCC    G  + CCP    +    +  I       V  ++   C         Q EA+E   S   V+ ++     C +   C    TCC      ++CC Y   VCC D  HCCP    C  +  SC ++
Sbjct:  315 GKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPLFSKTPALRQETKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCSGS----QCMIGEHSIPWFSKTPALKQKAKDVQCDDMYS-CADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDARGTCVLGQFSIPWLTKVPALPFDGTHSIC-DDTHTCPSGTTCCPGEGG-GWRCCPVEEVSKMVKRTVILLATACIVTLVSFSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVCLNHGTSCSRS 734          

HSP 4 Score: 183.341 bits (464), Expect = 3.349e-49
Identity = 128/356 (35.96%), Postives = 175/356 (49.16%), Query Frame = 3
Query:  459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-EIKISPILVES---IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            S C D  +C     G  ACCP +    C D  HCC   + C+ D   C              +PAS+  +VVCPD +S+C   +TCC ++   S+ CCP   AVCC D  HCCP N+ C++  G C S    +    KL    K        + C DG + C  G+TCC   D +YGCC   +AVCCSD L CCP  T C+L    C S+T +  LL  +   +    N+V C     +    +TCC+L +G  +GCCP   A CC+D +HCCP+   C  ++G C     ++     +P L      ++C +   C    TCC  A+  + CCP   AVCC DH HCCP   +CS
Sbjct:   83 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKK----ETCCRLVSG-KWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPALTHEARDVECDDMYSCPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 416          

HSP 5 Score: 152.91 bits (385), Expect = 9.678e-39
Identity = 120/369 (32.52%), Postives = 163/369 (44.17%), Query Frame = 3
Query:  411 LKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA--LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            L +  S++ + +CPD S C + S CC + G   Y CCP +                              EVV++  L +  S      CPD+  C +         G  ACCP +    C D  HCC   + C+ D   C              IPA +  ++ CPDG S C T  TCC++SD  S+GCCP   AVCC D + CCP N+ C++  G C S       + K       + +   RV C    + C DG TCC+     +YGCC   +A CCSD +HCCP  T C++    C  Q     L  ++  I  ES          +K TCC   +  + CCP   AVCC+DH HCCP   +CS
Sbjct:   27 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSR-SLPMILSQTSCSGCPDEYSCVN------TPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTKKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS 342          

HSP 6 Score: 124.02 bits (310), Expect = 3.770e-29
Identity = 98/295 (33.22%), Postives = 130/295 (44.07%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA--SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSV--VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS-----------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPN 1112
            G + CCP + AVCC D +HCCP    C+ ++     ++ E       K PA       V C D   C DG TCC +A G + CCP + AVCCSD  HCCPQ   C+   GTC   L +       KVPA        +C D   C  G+TCC   GG + CCP    V    KR      T C +   +  S   +++    L+  AI             L     D    C  G TCC    G + CC ++  VCC D + CCP   VC L+ GT  S++  P    ++  P+
Sbjct:  463 GDWGCCPIAQAVCCDDHEHCCPPGYTCSGSQ----CMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCSDHWHCCPQGFTCDA-RGTC--VLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCPVEE-VSKMVKRTVILLATACIVTLVS-FSFCPDIIIYYALQKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRGLGGVWNCCVYTQGVCCPDMVHCCPYGYVC-LNHGTSCSRSGSPRWDGQSGSPH 747          

HSP 7 Score: 115.161 bits (287), Expect = 3.110e-26
Identity = 92/327 (28.13%), Postives = 137/327 (41.90%), Query Frame = 3
Query:  606 SKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGG-SYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-DHQAEALEIKISPILVES-------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFPIIN 1544
            +K   +     L +  S++ + +CPD S C + S CC + G   Y CCP +                              EVV++    I + ++ S  CPD  S   T        +G   CCP +    C D   CC   + C+     C   + +             + V+CP  + +C    TCC +    S+GCCP   A CC D +HCCP N+ C++ +G C  +Q     +   P  V+S       + C +G+ C    TCC   + +Y CC   +AVCCSDH HCCP  T+C L  K C     +  +L + P I 
Sbjct:   16 NKAARMGPPWFLLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAA------------------------------EVVSRSLPMILSQTSCS-GCPDEYSCVNT-------PEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYCIPASNQ-------------SAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIR 291          
BLAST of Granulin b vs. Ensembl Xenopus
Match: trappc11 (trafficking protein particle complex 11 [Source:Xenbase;Acc:XB-GENE-5931148])

HSP 1 Score: 223.402 bits (568), Expect = 6.987e-63
Identity = 158/462 (34.20%), Postives = 211/462 (45.67%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV--VTKIKLKVPASSI---------LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL-KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-------TKKPSLLIKTFQPNPVNRVICPGAK------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCP---------------------------QNTVCNINKGTCDHQAEALEIKISPIL-----VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            S+ CCP   AVCC D  HCCP N+EC++ +G C S    +  ++K+  +V +  +           V C D + C DGSTCC     +Y CC   SAVCCSD  HCCP  T C+L    C S+  E     ++  +   S   V C   + C D +TCC ++   + CCPY+ AVCC D  HCCP    C+   G+C      +    K     +    ++C D +++C    TCC L  G +GCCP   AVCC+D L CCP+   C  S G C          TK P +   +     +  V+           Y C DGQTCC+L +GD +GCCP + A CC D  HCCP                           Q T C    G  D     L +  SP +      + +KC +   C    TCC  A+  + CCP   AVCC DH HCCP   +CS
Sbjct:  142 SWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDGTFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQC-DDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTC--SQGECSKMEHSIPWFTKTPMVFFLSLSLLSILPVVSVARDVECDDMYSCPDGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETACARRCGD-DEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 596          

HSP 2 Score: 211.46 bits (537), Expect = 1.133e-58
Identity = 161/455 (35.38%), Postives = 213/455 (46.81%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL-KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVV---TKMKLKI----------PAIS-NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-------TKKPSLLIKTF---------QPNPV----NRVICPG--AKY-------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
             D +Y CC   SAVCCSD  HCCP  T C+L    C S   E     ++  +   S   V C   + C D +TCC ++   + CCPY+ AVCC D  HCCP    C+   G+C      +    K          V C D + C +  TCC +  G + CCP   AVCC+D  HCCP+   C+   G C SK++  +   TK  +            P +S    +EC D  S C  G TCC L+ G +GCCP + AVCC D   CCP    C  S G C          +K P+L  +T           P P+    +  ICP   AKY        C+DGQTCC+L +GD +GCCP + A CC D  HCCP    C+ ++      +     K +P L    + ++C +   C    TCC  A+  + CCP   AVCC DH HCCP   +CS
Sbjct:  226 VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS--GGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCS--QGEC-SKMEHSIPWFTKTPMVFFLSLSLLSILPVVSVARDVECDDMYS-CPDGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTC--SGGQCQKGEHSIPLFSKTPALRQETACARRCGDDEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGD-WGCCPIAQAVCCDDHEHCCPPGYTCSGSQCMIGEHSIPWFSK-TPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS 670          

HSP 3 Score: 190.274 bits (482), Expect = 3.352e-51
Identity = 138/385 (35.84%), Postives = 192/385 (49.87%), Query Frame = 3
Query:  459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---------DSKLKEVVTKMKLKIPAISN--LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALEIKISPIL-VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF---PIINF 1547
            S C D  +C     G  ACCP +    C D  HCC   + C+ D   C              +PAS+  +VVCPD +S+C   +TCC ++   S+ CCP   AVCC D  HCCP N+ C++  G C          SKL   V    LK+  + +    + C DG + C  G+TCC   D +YGCC   +AVCCSD L CCP  T C+L    C S+T +  LL  +   +    N+V C  A   C D  TCC L + + +GCCPY+ A CC D IHCCP    C  + G+C   +H    +   ++  L    ++C + + C +K TCC   +  + CCP   AVCC+DH HCCP   +CS    S  ++ +  F   P++ F
Sbjct:   63 SGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLGDEERRVPCLDG-TFCPDGSTCCEQVDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPC-DATTSCPDKNTCCHL-SSEKWGCCPYAQAVCCDDHIHCCPSGFTC--SGGSCVLAEHSIPWMRKTLAQGLKTTRVQCDDTASCPEKETCCRLVSGKWGCCPVVKAVCCNDHLHCCPEGYTCSQGECSKMEHSIPWFTKTPMVFF 428          

HSP 4 Score: 169.088 bits (427), Expect = 5.283e-44
Identity = 136/430 (31.63%), Postives = 166/430 (38.60%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCP---------------------------QNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLS-----------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-------DSKTKKPSLLIKTFQPN-------PVNRVICPG------------------------------------AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGT 1289
            G + CCP + AVCC D +HCCP                           Q T C    G  +      +       P S    V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+     C      +    K          V C D   C DG TCC +A G + CCP + AVCC D  HCCP    C+   G C      +    K   LK     NL+           ++C D S  CK G TCC +  G +GCCP   AVCCSD   CCPQ   C+ + GTC          TK P+L               P     CPG                                    ++Y C DGQTCC+   G  + CC Y+   CC D +HCCP   VC +N GT
Sbjct:  466 GDWGCCPIAQAVCCDDHEHCCPPGYTCSGGQCQKGEHSIPLFSKTPALRQETACARRCGDDEYPFPLCLLFSPFICPFSVAKYVKCDDTHSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GSQCMIGEHSIPWFSKTPALKQKAKDVQCDDMYSCADGQTCCRLASGDWGCCPIAQAVCCDDHEHCCPPGYTCS--GGQCQKGEHSIPWYSKTPALKQEGKCNLANTPVNVFAGNIVKC-DDSFACKDGYTCCRMVSGVWGCCPIEKAVCCSDHWHCCPQGFTCD-ARGTCVLGQFSIPWLTKVPALPFDGTHSICDDTHTCPSGTTCCPGEGGGWRCCPVEEKEAIETSPSDTSVQGLRLDYVWCDSQYACFDGQTCCRG-LGGVWNCCVYTQGVCCPDMVHCCPYGYVC-LNHGT 887          

HSP 5 Score: 148.288 bits (373), Expect = 4.863e-37
Identity = 110/343 (32.07%), Postives = 150/343 (43.73%), Query Frame = 3
Query:  639 LKVPASSILSVVCPDQSQCNDGSTCCAVAG----------------------------------------GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ-AEALEIKISPILVES----IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCS 1490
            L +  S++ + +CPD S C + S CC + G                                        G  ACCP +    C D  HCC   + C+ D   C              IPA +  ++ CPDG S C T  TCC++SD  S+GCCP   AVCC D + CCP N+ C++  G C S             + K   L +     +   RV C    + C DG TCC+     +YGCC   +A CCSD +HCCP  T C++    C  Q  E   +   P + E     + C   + C  K TCC  +++ + CCPY  AVCC DH HCCP+  +CS
Sbjct:    7 LLLVVSTVSATLCPDGSTCGEKSLCCELPGKKGYGCCPAAEVVSRSLPMILSQTSCSGCPDEYSCVNTPEGGTACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC--------------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISNQDHIPWMSKLPARVKSEGLKLVGLG-DEERRVPCLDGTF-CPDGSTCCEQ-VDHTYGCCSILSAVCCSDHLHCCPGGTTCDLVHKKCVSQTGEGPLLPQMPAIREESANQVPCDATTSCPDKNTCCHLSSEKWGCCPYAQAVCCDDHIHCCPSGFTCS 332          

HSP 6 Score: 62.7734 bits (151), Expect = 1.212e-9
Identity = 64/208 (30.77%), Postives = 83/208 (39.90%), Query Frame = 3
Query:  903 CPDGSSTCKTGATCCLL-SDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            CPDGS TC   + CC L     YGCCP +  V                            P +L +T          C G    C D  +C   P G +  CCP +    C D  HCC   + C+ +   C          I      ++ CP+G S C    TCC  ++  S+ CCP P AVCC DH HCCP+N+ C +    C  N
Sbjct:   19 CPDGS-TCGEKSLCCELPGKKGYGCCPAAEVV------------------------SRSLPMILSQT---------SCSG----CPDEYSCVNTPEGGT-ACCPLAEGKSCQDGHHCCSVGSYCSDDGHYC----------IPASNQSAVVCPDGRSECPTLTTCCMMSDMSSWGCCPMPQAVCCDDHMHCCPHNSECDVQQGRCISN 177          
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 264.618 bits (675), Expect = 1.905e-80
Identity = 167/448 (37.28%), Postives = 232/448 (51.79%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-----KLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE----IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPII 1541
            +T  G+ SCCP+S  V C D  HCCPQ   C+ +  +C             ++  + + +V CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S      L +     K     S   SVVCPD ++QC D STCC +  G Y CCP  +A+CCSD  HCCPQ+TVC+L    C SK     T +  K+P      ++C D   +C  G TCC L+ G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K   P  +       +   C D        TCCKL +GD +GCCP   A CCSD  HCCPQ   C + +G C   D     LE     + +P+ +  I C   + C    TCCPS   S++CC  P+AVCC D  HCCP   +C++  ++C+K++  ++ P++
Sbjct:   88 LTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKC-DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGD-WGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVL 518          

HSP 2 Score: 264.233 bits (674), Expect = 2.871e-80
Identity = 165/451 (36.59%), Postives = 224/451 (49.67%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            +  DGS+ CCP   A CC D+ HCCP    C+L    C       ++LK+   + K     S   SVVCPD ++QC D STCC +  G Y CCP  +A+CCSD  HCCPQ+TVC+L    C SK     T +  K+P   +  V C  +  C +G TCC +  G++ CCP++ AVCC D  HCCP    C+ + GTC+        +K+V+  ++L  P I      C D  + C T  TCC L+ G +GCCP   AVCCSD   CCPQ   C L+ G C       + L K       P  +  + C      C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   TC+   + ++  +   L   V +++C  G  C    TCC  +   ++CCPY   VCC D  HCCP    CS     C +  + ++ +    P
Sbjct:  153 IMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQ-KTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPC-DDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDP 596          

HSP 3 Score: 219.55 bits (558), Expect = 1.948e-63
Identity = 141/374 (37.70%), Postives = 184/374 (49.20%), Query Frame = 3
Query:  426 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS---------KLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---QAEALEIKISP-------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            S  L   C     C  G +C     G+ +CCP+S  V C D  HCCPQ   C+ D  +C             ++  + + +V CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S         K     T   + +P     S+ CPD  + C   +TCC L  G YGCCP  NA+CCSD L CCPQ+TVC+L    C SK     LL K     PV  V C   +  C +G TCC+L  G ++GCCP++ A CC D IHCCP    C+  KGTC+    Q   ++  I+P       IL     C + + C    TCC   +  + CCP P AVCCSD+ HCCP   +C
Sbjct:   67 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLP----FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTK-LPGYPVKEVKC-DMEVSCPEGYTCCRLNTG-AWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC 421          

HSP 4 Score: 186.422 bits (472), Expect = 2.551e-51
Identity = 113/299 (37.79%), Postives = 148/299 (49.50%), Query Frame = 3
Query:  654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNR-------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--DHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            S  L   C     C  G +C     G+ +CCP+S  V C D  HCCPQ   C+ D  +C             ++      +++CP     C   ATCC++ DGS+GCCP   A CC D++ CCP    C+L    C S T   +LL K F     NR       V+CP AK QC D  TCC+LP G  YGCCP   A CCSD +HCCPQ+TVC++ +  C   +    L  K+    V+ +KC     C +  TCC     ++ CCP+  AVCC DH HCCP    C     +C+  IL
Sbjct:   67 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLL-KKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTG-KYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGIL 351          
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 110.538 bits (275), Expect = 6.163e-27
Identity = 78/270 (28.89%), Postives = 117/270 (43.33%), Query Frame = 3
Query:  348 ECNLNKGTCD------SVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASS-----ILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKI-PAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPV 1118
            +C+  KGTC+        +K+V+  ++L  P        C D ++C   +TCC +  G + CCP     C                       K   +V  ++ K+PA       I  + C   + C  G TCC    GS+ACC    AVCC D++HCCP    CN+ A TC+  +  +   + L + P + N  +EC +G   C    TCC  S G + CCP+   VCC D   CCP    C+     C   K  +  + ++   P P+
Sbjct:    3 QCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEGYC----------------------QKGDTMVAGLE-KIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGN--VECGEG-HFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDPVPRPL 246          

HSP 2 Score: 104.375 bits (259), Expect = 9.885e-25
Identity = 75/258 (29.07%), Postives = 109/258 (42.25%), Query Frame = 3
Query:  807 CNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            C+ + GTC+        +K+V+  ++L  P I      C D  + C T  TCC L+ G +GCCP     C               + AG      K P+      Q   +  + C      C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   TC+   + ++  +   L   V +++C  G  C    TCC  +   ++CCPY   VCC D  HCCP    CS     C +  + ++ +    P
Sbjct:    4 CHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPC-DDFTRCPTNNTCCKLNSGDWGCCPIPEGYCQKGD----------TMVAGL----EKIPARQTTPLQ---IGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDP 241          

HSP 3 Score: 99.7525 bits (247), Expect = 3.493e-23
Identity = 67/207 (32.37%), Postives = 91/207 (43.96%), Query Frame = 3
Query:  312 CSDKQHCCPQNTECNLNKGTC-------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL 893
            C D   C   NT C LN G               D+++  +      +     I  + C   + C  G TCC    GS+ACC    AVCC D++HCCP    CN+ A TC+  +  +   + L +    + +V C +   C+D  TCC  + G +ACCPY   VCC D RHCCP    C+     C  K K     M L+ P    L
Sbjct:   42 CDDFTRCPTNNTCCKLNSGDWGCCPIPEGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTL-GPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK-KIPRWDMFLRDPVPRPL 246          

HSP 4 Score: 87.4261 bits (215), Expect = 5.727e-19
Identity = 49/131 (37.40%), Postives = 66/131 (50.38%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSIL 665
            GS++CC    AVCC D+QHCCP    CN+   TC+  +  +   + L +    + +V C +   C+D  TCC  + G +ACCPY   VCC D RHCCP    C+     C  K K     M L+ P    L
Sbjct:  118 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTL-GPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK-KIPRWDMFLRDPVPRPL 246          
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 108.612 bits (270), Expect = 1.666e-25
Identity = 69/181 (38.12%), Postives = 95/181 (52.49%), Query Frame = 3
Query:  459 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASS-----ILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKI-PAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPF 983
            ++C   +TCC +  G + CCP   AVCCSD +HCCPQ   C L  G C  K   +V  ++ K+PA       I  + C   + C  G TCC    GS+ACC    AVCC D++HCCP    CN+ A TC+  +  +   + L + P + N  +EC +G   C    TCC  S G + CCP+
Sbjct:    3 TRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQ-KGDTMVAGLE-KIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGN--VECGEG-HFCHDNQTCCKDSAGVWACCPY 177          

HSP 2 Score: 107.071 bits (266), Expect = 6.281e-25
Identity = 63/165 (38.18%), Postives = 85/165 (51.52%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASS-----ILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPY 752
            G + CCP   AVCCSD QHCCPQ   C L +G C     + +     K+PA       I  + C   + C  G TCC    GS+ACC    AVCC D++HCCP    CN+ A TC+  +  +   + L +    + +V C +   C+D  TCC  + G +ACCPY
Sbjct:   17 GDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQK--GDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTL-GPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPY 177          

HSP 3 Score: 104.76 bits (260), Expect = 3.050e-24
Identity = 73/182 (40.11%), Postives = 96/182 (52.75%), Query Frame = 3
Query:  687 SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTK--KPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPY 1214
            ++C   +TCC +  G + CCP   AVCCSD +HCCPQ   C L  G C  K   +V  ++ KIPA     ++  D      ++C  G TCC    GS+ CC   +AVCC D+  CCP    CN+ A TC+      +P +L+ T  P  V  V C G  + C D QTCCK  AG  + CCPY
Sbjct:    3 TRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQ-KGDTMVAGLE-KIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLL-TLGPK-VGNVEC-GEGHFCHDNQTCCKDSAG-VWACCPY 177          

HSP 4 Score: 94.3597 bits (233), Expect = 1.204e-20
Identity = 54/139 (38.85%), Postives = 79/139 (56.83%), Query Frame = 3
Query: 1149 QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE----IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPII 1541
            +C    TCCKL +GD +GCCP   A CCSD  HCCPQ   C + +G C   D     LE     + +P+ +  I C   + C    TCCPS   S++CC  P+AVCC D  HCCP   +C++  ++C+K++  ++ P++
Sbjct:    4 RCPTNNTCCKLNSGD-WGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVL 140          

HSP 5 Score: 93.2041 bits (230), Expect = 2.767e-20
Identity = 64/178 (35.96%), Postives = 85/178 (47.75%), Query Frame = 3
Query:  918 STCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLL--IKTFQPNP--VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPY 1430
            + C T  TCC L+ G +GCCP   AVCCSD   CCPQ   C L+ G C       + L  I   Q  P  +  + C      C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   TC+   + ++  +   L   V +++C  G  C    TCC  +   ++CCPY
Sbjct:    3 TRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPY 177          
BLAST of Granulin b vs. Ensembl Mouse
Match: Grn (granulin [Source:MGI Symbol;Acc:MGI:95832])

HSP 1 Score: 96.6709 bits (239), Expect = 2.154e-22
Identity = 61/174 (35.06%), Postives = 80/174 (45.98%), Query Frame = 3
Query:  654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNR-------VICPGAKYQC 1154
            S  L   C     C  G +C     G+ +CCP+S  V C D  HCCPQ   C+ D  +C             ++      +++CP     C   ATCC++ DGS+GCCP   A CC D++ CCP    C+L    C S T   +LL K F     NR       V+CP AK QC
Sbjct:   54 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLL-KKFPAQKTNRAVSLPFSVVCPDAKTQC 214          

HSP 2 Score: 85.1149 bits (209), Expect = 1.997e-18
Identity = 46/123 (37.40%), Postives = 63/123 (51.22%), Query Frame = 3
Query:  924 CKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC 1292
            C  G +C L   G+  CCPFS  V C D   CCPQ   C+    +C   +            NP+  V CPG++++C D  TCC +  G S+GCCP   A+CC D++HCCP    C++    C
Sbjct:   67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSD-----------NPLGAVQCPGSQFECPDSATCCIMVDG-SWGCCPMPQASCCEDRVHCCPHGASCDLVHTRC 177          

HSP 3 Score: 82.8037 bits (203), Expect = 1.446e-17
Identity = 54/152 (35.53%), Postives = 74/152 (48.68%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-----KLKEVVTKMKLKVPASSILSVVCPD-QSQC 695
            +T  G+ SCCP+S  V C D  HCCPQ   C+ +  +C             ++  + + +V CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S      L +     K     S   SVVCPD ++QC
Sbjct:   75 LTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQC 214          

HSP 4 Score: 71.2478 bits (173), Expect = 1.137e-13
Identity = 43/127 (33.86%), Postives = 58/127 (45.67%), Query Frame = 3
Query: 1173 CKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFP 1535
            C L    +  CCP+S    C D  HCCPQ   C+ +  +C         ++S   + +++CP     C    TCC   + S+ CCP P A CC D  HCCP+  SC L    C        +L KFP
Sbjct:   73 CLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC--------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFP 191          
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28799|GRN_HUMAN (Progranulin OS=Homo sapiens OX=9606 GN=GRN PE=1 SV=2)

HSP 1 Score: 265.003 bits (676), Expect = 9.415e-80
Identity = 165/449 (36.75%), Postives = 223/449 (49.67%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI-------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV-------ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISP-ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            V  DGS+ CCP   A CC D+ HCCP    C+L    C  +       +  K+PA           SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA ++  V C  +  C DG TCC +  G++ CCP++ AVCC D  HCCP    C+   GTC+    +V    K    L +P    L  + P D  S+C +  TCC L+ G +GCCP   AVCCSD   CCPQ   C ++ G C    ++ S ++   +  P  R        I       C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   +C+ +      A  +  SP + V+ ++C  G  C    TCC      ++CCPY   VCC+D  HCCP    C+     C +    ++
Sbjct:  141 VMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRC--ITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKCDMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQC----QRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPS-LGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRW 580          

HSP 2 Score: 263.848 bits (673), Expect = 2.453e-79
Identity = 164/445 (36.85%), Postives = 229/445 (51.46%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQK------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFP 1535
             T  G+ SCCP+  AV C D  HCCP+   C+ +  +C             +   +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C        L + +   +     +   SV+CPD +S+C DGSTCC +  G Y CCP  +A CCSD  HCCPQ+TVC+L    C SK +   T +  K+PA +   ++C D   +C  G TCC L  G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K         P  + R +       C    TCC+L +G+ +GCCP   A CCSD  HCCPQ   C + +G C   +E +  ++  P    S+  P    C Q        TCCPS   S++CC  P+AVCC D  HCCP   +C++  +SC+K ++   P
Sbjct:   75 FTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQ-----------RSGNNSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSSSVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSK-ENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGE-WGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSEIVAGLEKMPARRASLSHPRDIGCDQHTSCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSCEKEVVSAQP 504          

HSP 3 Score: 234.187 bits (596), Expect = 3.966e-68
Identity = 144/377 (38.20%), Postives = 193/377 (51.19%), Query Frame = 3
Query:  408 KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPI-------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            K     S  L   C   + C+ G +C     G+ +CCP+  AV C D  HCCP+   C+ D  +C  +              +S+ ++ CPD Q +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C +        K++  +   +  A+S+ S+ CPD  S C  G+TCC L  G YGCCP  NA CCSD L CCPQ+TVC+L    C SK    + L+     + V  V C   +  C DG TCC+L +G ++GCCP++ A CC D IHCCP    C+  KGTC+   HQ   +E   + +       L   + C N S C    TCC   +  + CCP P AVCCSDH HCCP   +C
Sbjct:   48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGN-----------NSVGAIQCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTHPLAKKLPAQRTNRAVALSS-SVMCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTDLLTKLPAHTVGDVKC-DMEVSCPDGYTCCRLQSG-AWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTCEQGPHQVPWMEKAPAHLSLPDPQALKRDVPCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 410          
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28798|GRN_MOUSE (Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 SV=2)

HSP 1 Score: 264.618 bits (675), Expect = 9.720e-80
Identity = 167/448 (37.28%), Postives = 232/448 (51.79%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-----KLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE----IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPII 1541
            +T  G+ SCCP+S  V C D  HCCPQ   C+ +  +C             ++  + + +V CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S      L +     K     S   SVVCPD ++QC D STCC +  G Y CCP  +A+CCSD  HCCPQ+TVC+L    C SK     T +  K+P      ++C D   +C  G TCC L+ G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K   P  +       +   C D        TCCKL +GD +GCCP   A CCSD  HCCPQ   C + +G C   D     LE     + +P+ +  I C   + C    TCCPS   S++CC  P+AVCC D  HCCP   +C++  ++C+K++  ++ P++
Sbjct:   75 LTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKC-DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGD-WGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVL 505          

HSP 2 Score: 264.233 bits (674), Expect = 1.420e-79
Identity = 165/451 (36.59%), Postives = 224/451 (49.67%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT----FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            +  DGS+ CCP   A CC D+ HCCP    C+L    C       ++LK+   + K     S   SVVCPD ++QC D STCC +  G Y CCP  +A+CCSD  HCCPQ+TVC+L    C SK     T +  K+P   +  V C  +  C +G TCC +  G++ CCP++ AVCC D  HCCP    C+ + GTC+        +K+V+  ++L  P I      C D  + C T  TCC L+ G +GCCP   AVCCSD   CCPQ   C L+ G C       + L K       P  +  + C      C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   TC+   + ++  +   L   V +++C  G  C    TCC  +   ++CCPY   VCC D  HCCP    CS     C +  + ++ +    P
Sbjct:  140 IMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQ-KTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSK--NYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPC-DDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYCQKGDTMVAGLEKIPARQTTPLQIGDIGC-DQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDVDFIQPPVLLTLGPKVGNVECGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRKKIPRWDMFLRDP 583          

HSP 3 Score: 219.55 bits (558), Expect = 1.079e-62
Identity = 141/374 (37.70%), Postives = 184/374 (49.20%), Query Frame = 3
Query:  426 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS---------KLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---QAEALEIKISP-------ILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            S  L   C     C  G +C     G+ +CCP+S  V C D  HCCPQ   C+ D  +C             ++  + + +V CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S         K     T   + +P     S+ CPD  + C   +TCC L  G YGCCP  NA+CCSD L CCPQ+TVC+L    C SK     LL K     PV  V C   +  C +G TCC+L  G ++GCCP++ A CC D IHCCP    C+  KGTC+    Q   ++  I+P       IL     C + + C    TCC   +  + CCP P AVCCSD+ HCCP   +C
Sbjct:   54 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLLKKFPAQKTNRAVSLP----FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTK-LPGYPVKEVKC-DMEVSCPEGYTCCRLNTG-AWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKSDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC 408          

HSP 4 Score: 186.422 bits (472), Expect = 1.501e-50
Identity = 113/299 (37.79%), Postives = 148/299 (49.50%), Query Frame = 3
Query:  654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNR-------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--DHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            S  L   C     C  G +C     G+ +CCP+S  V C D  HCCPQ   C+ D  +C             ++      +++CP     C   ATCC++ DGS+GCCP   A CC D++ CCP    C+L    C S T   +LL K F     NR       V+CP AK QC D  TCC+LP G  YGCCP   A CCSD +HCCPQ+TVC++ +  C   +    L  K+    V+ +KC     C +  TCC     ++ CCP+  AVCC DH HCCP    C     +C+  IL
Sbjct:   54 SHHLDGSCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSC------------FQMSDNPLGAVQCPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGTHTLL-KKFPAQKTNRAVSLPFSVVCPDAKTQCPDDSTCCELPTG-KYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKNYTTDLLTKLPGYPVKEVKCDMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTCEMGIL 338          
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P23785|GRN_RAT (Progranulin OS=Rattus norvegicus OX=10116 GN=Grn PE=1 SV=3)

HSP 1 Score: 263.462 bits (672), Expect = 2.527e-79
Identity = 167/454 (36.78%), Postives = 226/454 (49.78%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD------SKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV-------ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            +  DGS+ CCP   A CC D+ HCCP    C+L    C S      +LK+   +   +  AS   SVVCPD ++QC D STCC +  G Y CCP  +A+CCSD  HCCPQ+TVC+L    C SK  +  T +  K+P   +  V C  +  C DG TCC +  G++ CCP++ AVCC D  HCCP    C+ + GTC+        +K+V   + L  P I    + C D SS C +  TCC LS G +GCCP   AVCC D   CCPQ   C +  G C    +K   ++   +  PV +        I       C  GQTCC    G S+ CC    A CC D+ HCCP    CN+   TC+  A +++  +       V +++C  G  C    +CC  +   ++CCPY   VCC D  HCCP    CS     C +    ++ I+   P
Sbjct:  140 IMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNRAVAS--FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--DYTTDLMTKLPGYPVNEVKCDLEVSCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFSS-CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYC----QKGDRMVAGLEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKG-SWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAGSVQPSMDLTFGSKVGNVECGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRKKTPRWDILLRDP 582          

HSP 2 Score: 257.299 bits (656), Expect = 5.858e-77
Identity = 168/451 (37.25%), Postives = 235/451 (52.11%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ----PNPV---NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---DHQAEALE---IKISPILVES-IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            +T  G+ SCCP+S  V C D QHCCP+   C+ +  +C  +   ++  ++            CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S       LK+   +   +  AS   SVVCPD ++QC D STCC +  G Y CCP  +A+CCSD  HCCPQ+TVC+L    C SK  +  T +  K+P      ++C D   +C  G TCC L+ G++GCCPF+ AVCC D + CCP    C+   GTC+    +   + K       P+P    N V C      C    TCC+L +GD +GCCP   A CC D  HCCPQ   C +++G C   D     LE   ++ + +L    I C   + C    TCCPS   S++CC  P+AVCC D  HCCP   +C++  ++C+K+     P ++ 
Sbjct:   75 LTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLLGAVQ------------CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNRAVAS--FSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--DYTTDLMTKLPGYPVNEVKC-DLEVSCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFS-SCPSNNTCCRLSSGD-WGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYCQKGDRMVAGLEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAGSVQPSMDL 505          

HSP 3 Score: 226.483 bits (576), Expect = 2.159e-65
Identity = 146/396 (36.87%), Postives = 197/396 (49.75%), Query Frame = 3
Query:  417 VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD----------HQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPI 1538
            +  S  L   C  +  C DG +C     G+ +CCP+S  V C D +HCCP+   C+ D  +C             ++  S + +V CP  Q +C D +TCC +  GS+ CCP   A CC D+ HCCP    C+L    C S       LK+   +   +  A+++ S+ CPD  + C   +TCC L  G YGCCP  NA+CCSD L CCPQ+TVC+L    C SK     L+ K     PVN V C   +  C DG TCC+L  G ++GCCP++ A CC D IHCCP    C+   GTC+              +L +    IL   + C + S C    TCC  ++  + CCP P AVCC DH HCCP    C ++   C K       L K P+
Sbjct:   51 IITSRRLDGSCQIRDHCPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCS------------QISDSLLGAVQCPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNR--AVASFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKDYTTDLMTK-LPGYPVNEVKC-DLEVSCPDGYTCCRLNTG-AWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYCQKGDRMVAGLEKMPV 428          

HSP 4 Score: 173.326 bits (438), Expect = 8.423e-46
Identity = 104/292 (35.62%), Postives = 144/292 (49.32%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCD------SVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPV 1118
            G++ CCP++ AVCC D  HCCP   +C+   GTC+        +K+V   + L  P      V C D S C   +TCC ++ G + CCP   AVCC D +HCCPQ   C +D G C    + V    K+ V  +++L    + C   + C  G TCC    GS+ACC    AVCC D++HCCP    CN+ A TC+     V   M L   +    ++EC  G   C    +CC  S G + CCP+   VCC D   CCP    C+     C   KT +  +L++   P P+
Sbjct:  299 GAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTCELGVLQVPWMKKVTASLSLPDPQILKNDVPCDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC-MDEGYCQKGDRMVAGLEKMPVRQTTLLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTCEKDAGSVQPSMDLTFGSKVG-NVECGAG-HFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRKKTPRWDILLRDPAPRPL 587          

HSP 5 Score: 115.546 bits (288), Expect = 7.256e-26
Identity = 86/264 (32.58%), Postives = 116/264 (43.94%), Query Frame = 3
Query:  801 TVCNLDAGT-----CDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-DHQAEALEIKISP-------ILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFP 1535
              C LD G      C+  L         ++     +   CPDG S       C L   G+  CCPFS  V C D   CCP+   C+    +C   +   SLL           V CPG++++C D  TCC +  G S+GCCP   A+CC D++HCCP    C++    C         +K  P       +   S+ CP+  + C    TCC      Y CCP PNA+CCSDH HCCP +T C L    C       +++ K P
Sbjct:   28 VACCLDQGGANYSCCNPLLDTWPIITSRRLDGSCQIRDHCPDGYS-------CLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISD--SLL---------GAVQCPGSQFECPDSATCCIMIDG-SWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTHPLLKKFPAQRTNRAVASFSVVCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKDYTTDLMTKLP 272          
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|P28797|GRN_CAVPO (Progranulin OS=Cavia porcellus OX=10141 GN=GRN PE=1 SV=2)

HSP 1 Score: 224.172 bits (570), Expect = 2.750e-64
Identity = 154/459 (33.55%), Postives = 219/459 (47.71%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVV-CPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL--KEVVTKMKLK-----------------VPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT-------------------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514
            +T  G+ +CCP+S A+ C D  HCCP    C+ + GTC            ++ P   +L  V CP  + +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C + L    + TK+  +                 +PA+   SV+CPD +SQC D +TCC +A G Y CCP  +A+CCSD  HCCPQ+TVC+L    C S+ K     +  K+P+ +   +EC D   +C  G TCC L  G +GCCPF  AVCC D + CCP+   C+    TC+    +     KT                     P P+   I       C+ G  CC+L +G+ +GCCP       S + + C     C +       +  A  + +S      + C   + C    TCCP     ++CC  P+AVCC D  HCCP   +C++  +SC+K
Sbjct:   75 LTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC------------IQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK--AKTLLTKLPSWTVWDVEC-DQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPPSPPGPLRSEISCDEVVSCAPGNICCRLASGE-WGCCP-------SSEGYLCMAGERCQVGDRLAPEKMAAHLMSLS--QTTDVGCDQHASCPVGQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSCEK 508          

HSP 2 Score: 220.32 bits (560), Expect = 6.945e-63
Identity = 154/468 (32.91%), Postives = 207/468 (44.23%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLK-------------------VPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS-------------------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCC-KLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVES------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC-SLNTKSCDKNILLKF 1532
            DGS+ CCP   A CC D+ HCCP    C+L    C + L       KL                    +PA+   SV+CPD +SQC D +TCC +A G Y CCP  +A+CCSD  HCCPQ+TVC+L    C S+ K     +  K+P+ ++  V C  +  C +G TCC +  G + CCP+  AVCC D  HCCP+   C+ +  TC+  L +V    K                             I C D   +C  G  CC L+ G +GCCP S    C     C           G   +  K  + L+   Q   V           C  GQTCC KL  G  + CC    A CC D  HCCP    CN+   +C+  A+   +  +P+ V S      + C +   C  + TCC  +   ++CCP+   VCC D  HCCP    C S  T+   K  LL +
Sbjct:  144 DGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK--AKTLLTKLPSWTVWDVECDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPPSPPGPLRSEISC-DEVVSCAPGNICCRLASGEWGCCPSSEGYLCMAGERC---------QVGDRLAPEKMAAHLMSLSQTTDVGC----DQHASCPVGQTCCPKL--GGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSCEKAADGAHLA-APLAVGSTGGVMDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKSLLHW 592          

HSP 3 Score: 193.741 bits (491), Expect = 3.869e-53
Identity = 124/320 (38.75%), Postives = 163/320 (50.94%), Query Frame = 3
Query:  405 IKLKVPA-SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV-CPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL--KEVVTKMKLK-----------------IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH 1298
            + L+  A S  L   C   + C  G +C   A G+ ACCP+S A+ C D  HCCP    C+ D GTC            ++ P   +L  V CP  + +C D STCC +  GS+ CCP   A CC D+ HCCP    C+L    C + L    + TK+  +                 +PA    S+ CPD  S C    TCCLL+ G YGCCP  NA+CCSD L CCPQ+TVC+L    C S+ K  +LL K      V  V C   +  C +GQTCC+L +G  +GCCP+  A CC D +HCCP+   C+  K TC+ 
Sbjct:   46 VDLRTTALSGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC------------IQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTK-LPSWTVWDVEC-DQEVSCPEGQTCCRLQSG-KWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQ 350          

HSP 4 Score: 188.348 bits (477), Expect = 4.479e-51
Identity = 117/323 (36.22%), Postives = 161/323 (49.85%), Query Frame = 3
Query:  654 SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL-SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNL-------SAGTCDSKTKKPSLLIK--TFQPNPV-----------NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--DHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            S  L   C   + C  G +C   A G+ ACCP+S A+ C D  HCCP    C+ D GTC            ++ P I  L +++CP G   C   +TCC + DGS+GCCP   A CC D++ CCP    C+L       + G+    TK P+        +  PV             VICP ++ QC D  TCC L +G+ YGCCP   A CCSD +HCCPQ+TVC++ +  C   ++A+ L  K+    V  ++C     C +  TCC   +  + CCP+P AVCC DH HCCP    C     +C++  LL+ P     P
Sbjct:   54 SGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC------------IQRPDIHLLGAVQCPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGE-YGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTKLPSWTVWDVECDQEVSCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPEGFRCHTEKDTCEQG-LLQVPWAQKTP 362          

HSP 5 Score: 128.257 bits (321), Expect = 4.199e-30
Identity = 85/254 (33.46%), Postives = 119/254 (46.85%), Query Frame = 3
Query:  861 MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC------------------DHQAEALEIKISPILV-----ESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC-----DKNILLKFP 1535
            + L+  A+S          + C  G +C L + G+  CCPFS A+ C D   CCP    C+   GTC    ++P + +       +  V CPG +++C D  TCC +  G S+GCCP   A+CC D++HCCP    C++    C                  ++        +SP L+      S+ CP+  S C    TCC  A+  Y CCP PNA+CCSDH HCCP +T C L    C      K +L K P
Sbjct:   46 VDLRTTALSGYLGRPCQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTC---IQRPDIHL-------LGAVQCPGGEFECPDSSTCCHMLDG-SWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNKAKTLLTKLP 288          
BLAST of Granulin b vs. UniProt/SwissProt
Match: sp|Q54QR7|GRN_DICDI (Granulin OS=Dictyostelium discoideum OX=44689 GN=grn PE=3 SV=1)

HSP 1 Score: 63.5438 bits (153), Expect = 7.818e-11
Identity = 31/65 (47.69%), Postives = 39/65 (60.00%), Query Frame = 3
Query: 1344 SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538
            S+KCP+GSLC    TCC +++ SY+CCP PNA CCSD  HCCP   +C      C     L+F  
Sbjct:   64 SVKCPDGSLCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNICKPQQGLRFSF 128          

HSP 2 Score: 58.5362 bits (140), Expect = 3.682e-9
Identity = 32/69 (46.38%), Postives = 41/69 (59.42%), Query Frame = 3
Query:  627 TKMKLKVPASSIL-SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 830
            TK  L++  +    SV CPD S C + +TCC+ + GSYACCP  +A CCSDK+HCCP    C      C
Sbjct:   50 TKKSLELTETQDFGSVKCPDGSLCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNIC 118          

HSP 3 Score: 58.151 bits (139), Expect = 5.266e-9
Identity = 32/69 (46.38%), Postives = 41/69 (59.42%), Query Frame = 3
Query:  399 TKIKLKVPASSIL-SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 602
            TK  L++  +    SV CPD S C + +TCC+ + GSYACCP  +A CCSDK+HCCP    C      C
Sbjct:   50 TKKSLELTETQDFGSVKCPDGSLCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNIC 118          

HSP 4 Score: 55.4546 bits (132), Expect = 4.254e-8
Identity = 33/70 (47.14%), Postives = 38/70 (54.29%), Query Frame = 3
Query:  855 TKMKLKIPAISNL-SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC 1061
            TK  L++    +  S++CPDGS  C    TCC  SDGSY CCP  NA CCSDK  CCP    C      C
Sbjct:   50 TKKSLELTETQDFGSVKCPDGS-LCPNSNTCCSASDGSYACCPTPNAQCCSDKQHCCPYQFTCGNGGNIC 118          
BLAST of Granulin b vs. TrEMBL
Match: K1PAM6 (Uncharacterized protein OS=Crassostrea gigas OX=29159 GN=CGI_10005248 PE=4 SV=1)

HSP 1 Score: 342.428 bits (877), Expect = 2.109e-103
Identity = 183/438 (41.78%), Postives = 258/438 (58.90%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNP----VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI----KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            G + CCP   AVCC+D +HCCP+NT+C +++G C     E++   + +       +VVCPD QS+C  G TCC +A G+Y CCP   AVCCSD +HCCP+ T C++ +G C+     V+  M  +       SV+CPD Q +C DG TCC +A G + CCP   AVCCSD +HCCP+NT C +  G C     E++  +K +   + + ++ CPDG S CK+G TCC L+ G+YGCCP   AVCCSD   CCP+ T C++S+G C+  +   + ++      P       V+CP  +++C DGQTCCKL +G  +GCCP   A CCSD  HCCP++T C +++G C  +A++L +    K+  +   ++ CP+G S C    TCC  A   Y CCP P AVCCSD  HCCP NT C +++  C +   L        P
Sbjct:   85 GQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCMRGTGEMLDWFEKEPALVRSENVVCPDGQSECKSGQTCCKLASGNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPENTKCEVSQGKCMRGTGEMLDWLKKEPAMLRSKNVVCPDGQSECKSGQTCCKLASGNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGS---TYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASG-QWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKC-IRADSLSMDWFEKLPALRTRNVVCPDGQSQCKDGQTCCKLATGQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKCKRGDELSMDWFAKLP 517          

HSP 2 Score: 342.043 bits (876), Expect = 2.768e-103
Identity = 193/460 (41.96%), Postives = 263/460 (57.17%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----------NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC----------------DHQAEALEIKISPILV----ESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            G+Y CCP   AVCCSD +HCCP+ T C+++ G C+     V+  +  +       SV+CPD Q +C DG TCC +A G + CCP   AVCCSD +HCCP++T C +  G C  +   +      K+PA    +VVCPD QSQC DG TCC +A G Y CCP   AVCCSD +HCCP+NT C++ +G C  +  E+      K+PA+ + ++ CPDG S CKT  TCC L+ G+YGCCP   AVCCSD   CCP+NT C++S+G C   T+   L++  F+  P+          + V+CP    +C DGQTCC L +G  YGCCP   A CCSD +HCCPQ T C+I +  C                  Q +  E     +L+    E+++CP+G S C    TCC +A  +Y CCP P AVCCSD  HCCP  T+C +++  C++        ++  P
Sbjct:  316 GNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKC-IRADSLSMDWFEKLPALRTRNVVCPDGQSQCKDGQTCCKLATGQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKC-KRGDELSMDWFAKLPALRSKNVVCPDGQSECKTSQTCCKLASGNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKC---TRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASG-KYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKLPTENVECPDGQSECKTGQTCCKTAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQP 769          

HSP 3 Score: 333.954 bits (855), Expect = 3.500e-100
Identity = 195/472 (41.31%), Postives = 261/472 (55.30%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC---DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---DSKLKEVVTKMKLKIPAISN---LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK---------------------TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD----HQAEALEIKISPILVESIKCPNGS-LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYYLFV 1577
            G + CCP   AVCCSD +HCCP++T+C +++G C   DS+  +   K+    PA    +VVCPD QSQC DG TCC +A G Y CCP   AVCCSD +HCCP+NT C++ +G C  +  E+      K+PA    +VVCPD QS+C    TCC +A G+Y CCP   AVCCSD +HCCP+NT C++ +G C   D  + +   KM L + +       S+ CPDG+S C+ G TCCLL+ G YGCCP  +AVCCSD + CCPQ T C++    C  K                        P LL+K     P   V CP  + +C  GQTCCK  AG+ YGCCP   A CCSD  HCCP+ T C+++ G C+    +  + ++ + + +   S+ CP+G   C    TCC  A+  + CCP P AVCC+D  HCCP NT C ++   C +   L        P       V
Sbjct:  393 GQWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKCIRADSLSMDWFEKL----PALRTRNVVCPDGQSQCKDGQTCCKLATGQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKC-KRGDELSMDWFAKLPALRSKNVVCPDGQSECKTSQTCCKLASGNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKCTRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASGKYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKL----PTENVECPDGQSECKTGQTCCKTAAGN-YGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCTRGTGLVLDWFEKLPALKRPGLV 854          

HSP 4 Score: 316.235 bits (809), Expect = 1.347e-93
Identity = 173/428 (40.42%), Postives = 240/428 (56.07%), Query Frame = 3
Query:  303 AVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISPILVESIKCPNGS-LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            AVCCSD +HCCP+ T C+++ G C      V+  +  +       SV+CPD Q +C DG TCC +A G + CCP   AVCC+D +HCCP+NT C +  G C     E++   + +       +VVCPD QS+C  G TCC +A G+Y CCP   AVCCSD +HCCP+ T C++ +G C+     V+  M  +   +   S+ CPDG   CK G TCC L+ G +GCCP   AVCCSD   CCP+NT C +S G C   T +   ++   +  P       V+CP  + +C  GQTCCKL +G+ YGCCP   A CCSD  HCCP+ T C+++ G C+  +    + ++ + + +   S+ CP+G   C    TCC  A+  + CCP P AVCCSD  HCCP +T C ++   C +   L        P
Sbjct:   18 AVCCSDMKHCCPEGTTCDVSSGKCKRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCMRGTGEMLDWFEKEPALVRSENVVCPDGQSECKSGQTCCKLASGNYGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPENTKCEVSQGKCMRGTGE---MLDWLKKEPAMLRSKNVVCPDGQSECKSGQTCCKLASGN-YGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPESTKCEVSQGKCIRADSLSMDWFEKLP 441          

HSP 5 Score: 308.531 bits (789), Expect = 1.224e-90
Identity = 187/447 (41.83%), Postives = 247/447 (55.26%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---DSKLKEVVTKMKLKVPA---SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----------LKEVVTKMKLK-----IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA-------EALEIKISPILVESIK------CPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            G Y CCP   AVCCSD +HCCP+NT+C+++ G C     E+      K+PA    +VVCPD QS+C    TCC +A G+Y CCP   AVCCSD +HCCP+NT C++ +G C   D  + +   KM L V +       SV+CPD  S+C DG TCC +A G Y CCP   AVCCSD  HCCPQ T C++    C  K           + ++  K + K     +  +   ++ECPDG S CKTG TCC  + G+YGCCP   AVCCSD   CCP+ T C++S+G C+   +  + ++      P       V+CP  +++C DGQTCCKL +G  +GCCP   A CC+D  HCCP+NT C +++G C           E L     P LVE IK      CP+    C  K TCC +    + CC Y NAVCC   ++CCP    C
Sbjct:  469 GQYGCCPIPKAVCCSDGKHCCPENTQCDVSSGKCKRG-DELSMDWFAKLPALRSKNVVCPDGQSECKTSQTCCKLASGNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKCTRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASGKYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKLPTENVECPDGQSECKTGQTCCKTAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCN---RGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASG-QWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCTRGTGLVLDWFEKLPALKRPGLVEMIKKDNTIVCPDQKTSCPDKNTCCKNKEGKFGCCAYNNAVCCKSGTYCCPKGYIC 910          

HSP 6 Score: 256.144 bits (653), Expect = 2.519e-71
Identity = 150/371 (40.43%), Postives = 202/371 (54.45%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC---DSVLKEVVTKIKLKVPA---SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK-----------LKEVVTKMKLKVPASSIL-----SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV-------------NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCN 1274
            G+Y CCP   AVCCSD +HCCP+NT+C+++ G C   D ++ +   K+ L V +       SV+CPD  S+C DG TCC +A G Y CCP   AVCCSD  HCCPQ T C++    C  K           + ++  K + K     +L     +V CPD QS+C  G TCC  A G+Y CCP   AVCCSD +HCCP+ T C++ +G C+     V+  M  +   +   S+ CPDG   CK G TCC L+ G +GCCP   AVCC+D   CCP+NT C +S G C   T+   L++  F+  P              N ++CP  K  C D  TCCK   G  +GCC Y+ A CC    +CCP+  +C+
Sbjct:  545 GNYGCCPIPKAVCCSDMKHCCPENTKCDVSSGKCTRGDGLIVDWFEKMPLAVRSRGQGEASSVMCPDGASECEDGQTCCLLASGKYGCCPIQDAVCCSDHVHCCPQGTKCDIQEKKCIGKPAANLGVISMDMIQIQGKGQEKSHPELLLKLPTENVECPDGQSECKTGQTCCKTAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKC---TRGTGLVLDWFEKLPALKRPGLVEMIKKDNTIVCPDQKTSCPDKNTCCKNKEG-KFGCCAYNNAVCCKSGTYCCPKGYICD 911          

HSP 7 Score: 144.821 bits (364), Expect = 1.003e-32
Identity = 93/285 (32.63%), Postives = 131/285 (45.96%), Query Frame = 3
Query:  870 KIPAI---SNLSIECPDGSS---------------------------------------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISPILVESIKCPNGS-LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            K PA+    N+++ C D                                                 CK G TCC L+ G +GCCP   AVCC+D   CCP+NT C +S G C   T +   ++  F+  P       V+CP  + +C  GQTCCKL +G+ YGCCP   A CCSD  HCCP+ T C+++ G C+  +    + ++ + + +   S+ CP+G   C    TCC  A+  + CCP P AVCCSD  HCCP NT C ++   C +        +   P
Sbjct:    7 KEPALVRSENVAVCCSDMKHCCPEGTTCDVSSGKCKRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCMRGTGE---MLDWFEKEPALVRSENVVCPDGQSECKSGQTCCKLASGN-YGCCPIPKAVCCSDMKHCCPEGTTCDVSSGKCNRGSTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCSDGKHCCPENTKCEVSQGKCMRGTGEMLDWLKKEP 287          

HSP 8 Score: 140.969 bits (354), Expect = 1.903e-31
Identity = 78/194 (40.21%), Postives = 110/194 (56.70%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----LKVPASSIL-----SVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCN 812
            T  G+Y CCP   AVCCSD +HCCP+ T C+++ G C+     V+  +  +       SV+CPD Q +C DG TCC +A G + CCP   AVCC+D +HCCP+NT C +  G C      V+   +    LK P    +     ++VCPDQ + C D +TCC    G + CC Y++AVCC    +CCP+  +C+
Sbjct:  718 TAAGNYGCCPLPKAVCCSDMKHCCPEGTTCDVSSGKCNRGNTYVMDWMDKQPAVVRAGSVMCPDGQHECKDGQTCCKLASGQWGCCPIPKAVCCNDGKHCCPENTKCEVSQGKCTRGTGLVLDWFEKLPALKRPGLVEMIKKDNTIVCPDQKTSCPDKNTCCKNKEGKFGCCAYNNAVCCKSGTYCCPKGYICD 911          
BLAST of Granulin b vs. TrEMBL
Match: A0A2G8L0S4 (Putative fibrillin-1 isoform X4 (Fragment) OS=Stichopus japonicus OX=307972 GN=BSL78_09258 PE=4 SV=1)

HSP 1 Score: 323.939 bits (829), Expect = 5.248e-100
Identity = 188/432 (43.52%), Postives = 254/432 (58.80%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPN--------AVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            +   G Y CCP  +AVCCSD  HCCP    C+ ++GTC S   E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+ + +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +   +  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C++++GTC   +E +    K     V ++ CP G S C    TCC  ++  Y CCP PN        AVCCSDH HCCPN  +C ++  +C + 
Sbjct:  165 ILATGRYGCCPLRNAVCCSDHLHCCPNGYTCDASQGTC-SQGSEIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIMAWFE-KTEATPVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDISGGTCSQGSEIMNWFEKT-EATTLGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMNWFEKTEATTVGTVTCPGGQSECPDGSTCCLLSSGQYGCCPLPNCKILLILQAVCCSDHLHCCPNGYTCDVSQGTCSQG 588          

HSP 2 Score: 308.531 bits (789), Expect = 6.021e-94
Identity = 189/445 (42.47%), Postives = 248/445 (55.73%), Query Frame = 3
Query:  270 DGSYSCCP---YSSAVCCSDK--------------QHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            DG Y CCP   Y+    CS+                HCCP+   C+ ++  C      V      K  A  + SV+CPD+ S+C DGSTCC +A G Y CCP  +AVCCSD  HCCP    C+   GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A    ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +   V  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C+I+ GTC   +E +    K     + ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C +   I+  F
Sbjct:   76 DGKYGCCPCPKYTCTALCSEDICSSSLFVKAECCDTHCCPEGFSCDGDQ--CSKEEGNVFVAGVSKTEAVIVESVMCPDRRSECPDGSTCCILATGRYGCCPLRNAVCCSDHLHCCPNGYTCDASQGTC-SQGSEIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIMAWFE-KTEATPVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDISGGTCSQGSEIMNWFEKTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMNWF 512          

HSP 3 Score: 291.197 bits (744), Expect = 2.212e-87
Identity = 182/433 (42.03%), Postives = 237/433 (54.73%), Query Frame = 3
Query:  303 AVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCP---YSSAVCCSD--------------KRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            AVCCSD +HCCP    C++++GTC S   E +   + +V      +V C  +  C DG+TCC  A G Y CCP   Y+    CS+                HCCP+   C+ D   C  +   V      K  A  + SV+CPD +S+C DGSTCC +A G Y CCP  +AVCCSD  HCCP    C+   GTC S+  E++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +  PV  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C+++ GTC   +E +    K     V ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C +   I+  F
Sbjct:   16 AVCCSDGEHCCPSGYTCDVSEGTCSSE-SEKLPWFEKEVAK----NVHCGGKYYCKDGNTCCPQADGKYGCCPCPKYTCTALCSEDICSSSLFVKAECCDTHCCPEGFSCDGDQ--CSKEEGNVFVAGVSKTEAVIVESVMCPDRRSECPDGSTCCILATGRYGCCPLRNAVCCSDHLHCCPNGYTCDASQGTC-SQGSEIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMAWFEKT-EATPVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDISGGTCSQGSEIMNWF 437          
BLAST of Granulin b vs. TrEMBL
Match: A0A2B4SIQ6 (Granulin OS=Stylophora pistillata OX=50429 GN=GRN PE=4 SV=1)

HSP 1 Score: 333.954 bits (855), Expect = 6.825e-99
Identity = 195/437 (44.62%), Postives = 257/437 (58.81%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKV--PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAI----SNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVES----IKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            + G Y CCP   AVCCSD +HCCP    C+++ GTC      +    KL      S   SVVCPD +SQC DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++ AG+C   S    +V K+   +   S  +VVCPD QS+C DG+TCC ++ G Y CCPY +AVCCSD  HCCP    C++ AGTC      +   M  K+PA+    +  ++ CPDG S C  G TCC LS G YGCCP+ NAVCCSD   CCP    C++SAGTC  ++    ++ K     +    + V+CPG + +C DG TCCKL +G  YGCCPY  A CCSD+ HCCP    C+++ GTC   + ++E+  K+  +  ES    + CP+G S C    TCC  +   Y CCP PNAVCCSD  HCCPN  +C ++  +C + 
Sbjct:  339 SSGQYGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTCSKGTTSITFLQKLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQYGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPALMREKSASNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSI--PMVQKLPALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQESSSMPMMQKLPALIRERNASNVVCPGGQSECPDGNTCCKLSSGQ-YGCCPYPNAVCCSDREHCCPSGYTCDVSAGTCTQGSSSIEMFQKMPAMKRESAASYVVCPDGESECPDGTTCCKLSTGQYGCCPLPNAVCCSDGVHCCPNGYTCDVSAGTCTQG 772          

HSP 2 Score: 327.405 bits (838), Expect = 1.877e-96
Identity = 193/448 (43.08%), Postives = 257/448 (57.37%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAE---ALEIKISPILVESIKCPNGSLCGQK-------GTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            + G Y CCPY +AVCCSD +HCCP    C+++ GTC  +S    ++ K+   +   +  +VVCP  QS+C DG+TCC ++ G Y CCPY +AVCCSD+ HCCP    C++ AGTC   S   E+  KM      S+   VVCPD +S+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++ AGTC   S    +V K+   +   +  ++ CPDG S C  G TCC LS G YGCCP+ NAVCCSD   CCP    C++SAGTC   +    ++ +     +    + V+CPG + +C DG TCC+L +G  YGCCP   A CCSD  HCCP    C+++ GTC   +    +L++  +   V  IK  +G LC  K        TCC   + +Y CCP  NAVCCSDH HCCPN  +C +    C KN      I N 
Sbjct:  576 SSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQESSSMPMMQKLPALIRERNASNVVCPGGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDREHCCPSGYTCDVSAGTCTQGSSSIEMFQKMPAMKRESAASYVVCPDGESECPDGTTCCKLSTGQYGCCPLPNAVCCSDGVHCCPNGYTCDVSAGTCTQGSSSIPMVQKLAALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSMPMVQRLPALKREKDASNVVCPGGQSECPDGNTCCRLSSGQ-YGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSGTYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHIKMIANV 1022          

HSP 3 Score: 327.405 bits (838), Expect = 2.079e-96
Identity = 193/450 (42.89%), Postives = 258/450 (57.33%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL----SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------KISPILVES--IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544
            + G Y CCPY +AVCCSD++HCCP    C+++ GTC   S   E+  K+      S+   VVCPD +S+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++ AGTC   S    +V K+   +   +  +VVCPD QS+C DG+TCC ++ G Y CCPY +AVCCSD  HCCP    C++ AGTC      +   M  ++PA+       ++ CP G S C  G TCC LS G YGCCP  NAVCCSD   CCP    C++SAGTC   +      +  + L        V+ V+CP  KYQC +G TCC++P+G +YGCCP   A CCSD IHCCP    C++  G C   AE +++        S +  E   IKCP+G  C    TCC  ++  + CCP P+AVCC DH HCCP+   C L  + C     ++ P++ 
Sbjct:  655 SSGQYGCCPYPNAVCCSDREHCCPSGYTCDVSAGTCTQGSSSIEMFQKMPAMKRESAASYVVCPDGESECPDGTTCCKLSTGQYGCCPLPNAVCCSDGVHCCPNGYTCDVSAGTCTQGSSSIPMVQKLAALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSM--PMVQRLPALKREKDASNVVCPGGQSECPDGNTCCRLSSGQYGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSG-TYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHIKMIANVPSSRSSVDTEQKYIKCPDGCSCLDYETCCVLSDGRFGCCPLPHAVCCEDHEHCCPSGYRCDLAAEMCVTGN-VRLPMLQ 1100          

HSP 4 Score: 325.865 bits (834), Expect = 6.744e-96
Identity = 200/455 (43.96%), Postives = 264/455 (58.02%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL-KVPA----SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPA----SSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL----SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVE----SIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPII 1541
            + G Y CCP   AVCCSD +HCCP    C+++ GTC    K   T I L K+PA    S   SVVCPD +SQC DG+TCC +  G Y CCP   AVCCSD +HCCP    C++ AGTC      +   M  K PA    S+  ++VCPD +S+C D +TCC ++ G Y CCP   AVCCSD  HCCP    C++ AGTC SK    +T ++ K+PA+       S+ CPDG S C  G TCC LS G YGCCP  NAVCCSD   CCP    C++SAG+C   +    ++ K     +    + V+CP  + +C DG TCCKL +G  YGCCPY  A CCSD  HCCP    C+++ GTC   + ++ +  K+  ++ E    ++ CP+G S C    TCC  ++  Y CCPYPNAVCCSD  HCCPN  +C ++  +C +      ++ K P +
Sbjct:  181 SSGQYGCCPLPKAVCCSDGEHCCPNGYTCDISAGTCS---KGTTTLILLQKLPAVQRKSDANSVVCPDGESQCPDGNTCCKLFSGQYGCCPLPKAVCCSDGKHCCPDGYTCDVSAGTCTQGSSSIA--MFQKKPAMKRESAESNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTC-SKGTTSITFLQ-KLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQYGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPALMREKSASNVVCPDGQSECPDGNTCCKLSSGQ-YGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSIPMVQKLPALMREKNGSNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQESSSMPMMQKLPAL 627          

HSP 5 Score: 291.197 bits (744), Expect = 4.234e-83
Identity = 179/420 (42.62%), Postives = 232/420 (55.24%), Query Frame = 3
Query:  357 LNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKV--PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIE----CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIK---TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVE----SIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPII 1541
            +N GTC   S    +  K   K   S+  ++VCPD +S+C D +TCC ++ G Y CCP   AVCCSD  HCCP    C++ AGTC      ++   KL      S   SVVCPD +SQC DG+TCC +  G Y CCP   AVCCSD +HCCP    C++ AGTC      +   M  K PA+   S E    CPDG S C    TCC LS G YGCCP   AVCCSD   CCP    C++SAGTC   T   + L K     + +  N V+CP  + QC DG TCCKL  G  YGCCP   A CCSD  HCCP    C+++ G+C   + ++ +  K+  ++ E    ++ CP+G S C    TCC  ++  Y CCPYPNAVCCSD  HCCPN  +C ++  +C +      ++ K P +
Sbjct:  132 VNAGTCTQGSSSIAMFQKKPAKKRESAASNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDISAGTCSKGTTTLILLQKLPAVQRKSDANSVVCPDGESQCPDGNTCCKLFSGQYGCCPLPKAVCCSDGKHCCPDGYTCDVSAGTCTQGSSSIA--MFQKKPAMKRESAESNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTCSKGTTSITFLQKLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQ-YGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPALMREKSASNVVCPDGQSECPDGNTCCKLSSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSIPMVQKLPAL 548          

HSP 6 Score: 224.557 bits (571), Expect = 1.558e-59
Identity = 170/469 (36.25%), Postives = 229/469 (48.83%), Query Frame = 3
Query:  333 CPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYA-CCP--YS--SAVCCS--------------------DKRHCCPQNTVCNL--------------DAGTC--DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNL----SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVE------SIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPII 1541
            C Q T CN ++   ++VL    T  ++ V    + +VVCP    QC  G +CC+V G     CCP  YS  S VC                      D ++ CP  ++                 +AGTC   S    +  K   K   S+  ++VCPD +S+C D +TCC ++ G Y CCP   AVCCSD  HCCP    C++ AGTC      ++   KL  PA+       S+ CPDG S C  G TCC L  G YGCCP   AVCCSD   CCP    C++SAGTC   +       KKP++  ++ + N    ++CP  + +C D  TCCKL +G  YGCCP   A CCSD  HCCP    C+++ GTC     ++        V+      S+ CP+G S C    TCC  +   Y CCP PNAVCCSD  HCCPN  +C ++  SC +      ++ K P +
Sbjct:   13 CSQVTFCNADELKENTVLS-AFTSNEIDV----LDAVVCPGGVRQCPSGHSCCSVPGNDEVHCCPVGYSCESGVCQETRKDNIAALFPSVGAKIVKCDNQYACPDRSIIIFMILILCLTCIIIVVNAGTCTQGSSSIAMFQKKPAKKRESAASNIVCPDGESECPDDTTCCKLSSGQYGCCPLPKAVCCSDGEHCCPNGYTCDISAGTCSKGTTTLILLQKL--PAVQRKSDANSVVCPDGESQCPDGNTCCKLFSGQYGCCPLPKAVCCSDGKHCCPDGYTCDVSAGTCTQGSSSIAMFQKKPAMKRESAESN----IVCPDGESECPDDTTCCKLSSGQ-YGCCPLPKAVCCSDGEHCCPNGYTCDVSAGTCSKGTTSITFLQKLPAVQRKSDANSVVCPDGESQCPDGTTCCKLSTGQYGCCPLPNAVCCSDGEHCCPNGYTCDVSAGSCTQGSSSIPMVQKLPAL 469          

HSP 7 Score: 205.682 bits (522), Expect = 5.422e-53
Identity = 122/297 (41.08%), Postives = 167/297 (56.23%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVT-KMKLKVPASSIL----SVVCPDQS-QCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA------ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPN 1112
            + G Y CCPY +AVCCSD +HCCP    C+++ GTC   S    +V ++          +VVCP  QS+C DG+TCC ++ G Y CCP  +AVCCSD +HCCP    C++ AGTC      + + +M   + A + +     V+CPD+  QC +GSTCC V  G+Y CCP  +AVCCSD  HCCP    C+++ G C    + +  KM   +P+           I+CPDG S C    TCC+LSDG +GCCP  +AVCC D   CCP    C+L+A  C +   +  +L K   P 
Sbjct:  813 SSGQYGCCPYPNAVCCSDGEHCCPNGYTCDVSAGTCTQGSSSMPMVQRLPALKREKDASNVVCPGGQSECPDGNTCCRLSSGQYGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSGTYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHI--KMIANVPSSRSSVDTEQKYIKCPDGCS-CLDYETCCVLSDGRFGCCPLPHAVCCEDHEHCCPSGYRCDLAAEMCVTGNVRLPMLQKIRSPR 1106          

HSP 8 Score: 140.969 bits (354), Expect = 2.522e-31
Identity = 83/225 (36.89%), Postives = 118/225 (52.44%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVT-----KIKLKVPASSILSVVCPDQS-QCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPAS------SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS------KLKEVVTKMKLKIPAIS 887
            + G Y CCP  +AVCCSD +HCCP    C+++ GTC      + +      ++      ++  V+CPD+  QC +GSTCC V  G+Y CCP  +AVCCSD  HCCP    C+++ G C    + +  KM   VP+S          + CPD   C D  TCC ++ G + CCP   AVCC D  HCCP    C+L A  C +       L+++ +  K K P ++
Sbjct:  892 SSGQYGCCPLPNAVCCSDGKHCCPNGYTCDVSAGTCKQGSSSIASLQMHAALQAVTYIKAVDGVLCPDKKYQCPNGSTCCRVPSGTYGCCPIKNAVCCSDHIHCCPNGYTCDVEGGKCIKNAEHI--KMIANVPSSRSSVDTEQKYIKCPDGCSCLDYETCCVLSDGRFGCCPLPHAVCCEDHEHCCPSGYRCDLAAEMCVTGNVRLPMLQKIRSPRKQKTPRVN 1114          
BLAST of Granulin b vs. TrEMBL
Match: W4Z754 (Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=4 SV=1)

HSP 1 Score: 337.806 bits (865), Expect = 4.197e-98
Identity = 193/431 (44.78%), Postives = 246/431 (57.08%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V+   K       + SVVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + SVVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P     V+CP  + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+LVE++ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C +   ++L +
Sbjct:  324 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWY 752          

HSP 2 Score: 335.109 bits (858), Expect = 3.577e-97
Identity = 192/424 (45.28%), Postives = 240/424 (56.60%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ-PNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + SV+CP  Q+QC DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + AGTC      V+   K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC           K+   P  V  VICPG + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+ VE++ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct:  863 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVKSVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVLWFEKSAATPVQVESVICPGGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 1284          

HSP 3 Score: 333.569 bits (854), Expect = 1.095e-96
Identity = 189/430 (43.95%), Postives = 239/430 (55.58%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI----KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K       + SV+CP  Q+QC DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + AGTC      V+   K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V+   K     +   S+ CP G S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC      +        +P+ VES+ CP G + C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C ++  +C +   ++L +
Sbjct:  940 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVKSVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVLWFEKSAATPVQVESVICPGGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVESVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWY 1368          

HSP 4 Score: 333.183 bits (853), Expect = 1.576e-96
Identity = 192/427 (44.96%), Postives = 244/427 (57.14%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + SV+CP  Q+QC DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + AGTC      V+   K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   T+  S+++        P  V  V+CPG + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+ VE++ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct: 1171 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVESVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTC---TQGESVVLWYEKSAATPVQVESVLCPGGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 1592          

HSP 5 Score: 332.413 bits (851), Expect = 2.616e-96
Identity = 191/432 (44.21%), Postives = 244/432 (56.48%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSIL--SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI----KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            G Y CCP  +AVCCSD  HCCP    C ++ GTC     E V     K  A+ +L  +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V+   K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC      +        +P+ V+S+ CP G + C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C ++  +C +   ++L +
Sbjct:  632 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTC--TQGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVSWYEKSAATPVQVKSVICPGGQAQCPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSAGTCTRGESVVLWY 1060          

HSP 6 Score: 330.872 bits (847), Expect = 8.981e-96
Identity = 190/424 (44.81%), Postives = 240/424 (56.60%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + SVVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V+   K     +   S+ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+  E++ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct:  170 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 591          

HSP 7 Score: 328.946 bits (842), Expect = 3.879e-95
Identity = 188/423 (44.44%), Postives = 236/423 (55.79%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K       + SVVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K         +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C ++ GTC      +    +   +P+ VE++ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct:  401 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 822          

HSP 8 Score: 328.561 bits (841), Expect = 6.021e-95
Identity = 191/427 (44.73%), Postives = 250/427 (58.55%), Query Frame = 3
Query:  282 SCCPYSSAVCCSDKQHCCPQNTECNLNKGTC---DSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
             CC Y +AVCCSD +HCCP   EC++   TC   + V++ ++T +      S+  +V+CPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K     +   S+ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   T+  S+++     +  P  V  V+CP  + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+ VES+ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct:   98 GCCTYPNAVCCSDGRHCCPTGYECDVTSNTCIKGNDVMRMLITDL-----TSNASAVICPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTC---TRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 514          

HSP 9 Score: 328.176 bits (840), Expect = 8.022e-95
Identity = 189/424 (44.58%), Postives = 240/424 (56.60%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K         +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V+   K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+ VE++ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct:  555 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHEENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVLVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVQVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 976          

HSP 10 Score: 325.094 bits (832), Expect = 8.032e-94
Identity = 186/424 (43.87%), Postives = 239/424 (56.37%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G Y CCP  +AVCCSD  HCCP    C ++ GTC      V    K       + +VVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K       + SV+CP  Q+QC DG+TCC +  G Y CCP  +AVCCSD  HCCP    C++ AGTC      V+   K     +   S+ CP G + C  G TCC L  G YGCCP  NAVCCSD   CCP    C++SAGTC   ++  P     +  P  +  V+CP  + +C DG TCCKL +G  YGCCP  +A CCSD +HCCP    C+++ GTC  Q E++     +   +P+ +ES+ CP+G S C    TCC  A+  Y CCP PNAVCCSD  HCCP+  +C ++  +C + 
Sbjct: 1479 GQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVQVDSVICPGGQAQCPDGNTCCKLPSGQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVLWYEKSSATPVQVESVVCPGGQAQCPDGNTCCKLPSGQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQ-YGCCPIPSAVCCSDHLHCCPSGYTCDVSAGTCT-QGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPLPNAVCCSDGQHCCPSGYTCDVSAGTCTQG 1900          

HSP 11 Score: 322.783 bits (826), Expect = 4.844e-93
Identity = 196/441 (44.44%), Postives = 241/441 (54.65%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI-----------KISPILVESIK-CPNG-SLCGQKGTCCP-SANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIIN 1544
            G Y CCP  +AVCCSD +HCCP    C+++ GTC      V+   K       + SVVCP  Q+QC DG+TCC +  G Y CCP  +AVCCSD  HCCP    C++ AGTC      V    K       I SVVCPD QS+C DGSTCC +A G Y CCP  SAVCCSD  HCCP    C++ AGTC      V    K     +   S+ CPDG S C  G+TCC L+ G YGCCP  NAVCCSD   CCP    C++SAGTC   ++  P     +  P  V  V+CP  + +C DG TCCKL +G  YGCCP   A CCSD +HCCP    C ++ GTC   +  LE            K+     E +  CP+  + C    TCCP  A+  + CCP  NAVCC DH HCCP+  SC  N  SC K   +  P+++
Sbjct: 1633 GQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVLWYEKSSATPVQVESVVCPGGQAQCPDGNTCCKLPSGQYGCCPLPNAVCCSDGEHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPIPSAVCCSDHLHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPLPNAVCCSDGQHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVYVESVVCPDGQSECPDGNTCCKLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGSSILEWSSKSSARSNVDKLQITATEPVSICPDSKTSCPSSSTCCPLMASGEWGCCPVHNAVCCDDHIHCCPSGYSCGTN--SCQKGS-MHLPLLS 2069          

HSP 12 Score: 270.011 bits (689), Expect = 8.875e-75
Identity = 158/365 (43.29%), Postives = 205/365 (56.16%), Query Frame = 3
Query:  456 QSQCNDG----STCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            ++ C DG    STCC        CC Y +AVCCSD RHCCP    C++ + TC       V +M +    S+  +V+CPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC      V    K     +   ++ CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C ++ GTC      +    +   +P+ VES+ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C + 
Sbjct:   76 ENTCKDGCATTSTCCNDLNNESGCCTYPNAVCCSDGRHCCPTGYECDVTSNTCIKGND--VMRMLITDLTSNASAVICPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWYEKSSATPVHVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQG 437          

HSP 13 Score: 263.077 bits (671), Expect = 2.133e-72
Identity = 184/468 (39.32%), Postives = 233/468 (49.79%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC--DSKLKEVVTKM-------KLKIPAISNLSIECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT---------------------------FQPNP--VNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            G Y CCP  SAVCCSD  HCCP    C+++ GTC      V    K       I SVVCPD QS+C DGSTCC +A G Y CCP  +AVCCSD +HCCP    C++ AGTC      V    K       + SVVCPD QS+C DG+TCC +A G Y CCP  +AVCCSD  HCCP    C + +GTC   S + E  +K        KL+I A   +SI CPD  ++C + +TCC L++ G +GCCP  NAVCC D + CCP    C  +  +C   +    LL K+                           FQP+      VICPG K +C DG  CC L  GD Y CCP   A                           E+ +  + P  + S  CP GS      TCC +  + Y CCPY  A+CCSD  HCCP++ SC+ +T +C K+  +  P +   P
Sbjct: 1787 GQYGCCPIPSAVCCSDHLHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVQIESVVCPDGQSECPDGSTCCKLASGQYGCCPLPNAVCCSDGQHCCPSGYTCDVSAGTCTQGESVVPWYEKSSATPVYVESVVCPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGSSILEWSSKSSARSNVDKLQITATEPVSI-CPDSKTSCPSSSTCCPLMASGEWGCCPVHNAVCCDDHIHCCPSGYSCGTN--SCQKGSMHLPLLSKSTGLLKLTFEGQEEPKPEVKVHDNKHLLFQPDEPRTGSVICPGGKIECQDGNACCLLAGGD-YSCCPLPQAV----------------------SPHEESGDKMMCPDEISS--CPTGS------TCCQTPGNIYGCCPYQAAICCSDLIHCCPSDYSCNSSTGTCTKDDHI-MPWVGKIP 2219          

HSP 14 Score: 211.46 bits (537), Expect = 8.681e-55
Identity = 131/325 (40.31%), Postives = 178/325 (54.77%), Query Frame = 3
Query:  606 SKLKEVVTKMKLKVPASSILSVVCPDQSQCNDG----STCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC---DSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            + L  +     LKV     L+     ++ C DG    STCC        CC Y +AVCCSD RHCCP    C++ + TC   +  ++ ++T +     A+      CPDG S C  G TCC L+ G YGCCP  NAVCCSD L CCP    C +S+GTC   ++  P     +  P  V  V+CP  + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C ++ GTC  Q E++     +   +P+ VES+ CP+G S C    TCC  A+  Y CCP PNAVCCSDH HCCP+  +C +++ +C +   ++L +
Sbjct:   54 ASLVSLAFGGPLKVSKVEELA----KENTCKDGCATTSTCCNDLNNESGCCTYPNAVCCSDGRHCCPTGYECDVTSNTCIKGNDVMRMLITDLTSNASAVI-----CPDGQSECPDGNTCCKLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTQGESVVPWYEKSSATPVHVENVVCPDGQSECPDGNTCCTLASGQ-YGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCT-QGESVVPWYEKSSATPVHVESVVCPDGQSECPDGNTCCTLASGQYGCCPLPNAVCCSDHLHCCPSGYTCGVSSGTCTRGESVVLWY 367          
BLAST of Granulin b vs. TrEMBL
Match: A0A2G8KIP6 (Putative kielin/chordin-like protein isoform X1 OS=Stichopus japonicus OX=307972 GN=BSL78_15248 PE=4 SV=1)

HSP 1 Score: 333.569 bits (854), Expect = 9.205e-97
Identity = 192/431 (44.55%), Postives = 259/431 (60.09%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK--NILLKF 1532
            + + G Y CCP  +AVCCSD  HCCP    C+++ GTC S   E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E+++  + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  S   KT +   V  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C++  GTC   +E +    K     V ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C +  +I+  F
Sbjct:  332 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMNWFE-KTKATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMSWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMSWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMSWFEKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWF 754          

HSP 2 Score: 333.183 bits (853), Expect = 1.543e-96
Identity = 187/431 (43.39%), Postives = 254/431 (58.93%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            + + G Y CCP  +AVCCSD  HCCP    C++  GTC    + +    K +  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+   ++   + K  A + +++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +   V  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C+++ GTC   +E +    K     + ++ CP G S C    TCC   +  Y CCP PNAVCCSDH HCCPN  +C ++  +C +   I+  F
Sbjct: 1232 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMAWFEKTETEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSAIINWFE-KTEATTLVTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSETMAWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIINWFEKTEATTLGTVTCPGGQSECPDGNTCCLLFSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWF 1656          

HSP 3 Score: 332.413 bits (851), Expect = 2.350e-96
Identity = 190/431 (44.08%), Postives = 261/431 (60.56%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK--NILLKF 1532
            + + G Y CCP  +AVCCSD  HCCP    C+++ GTC S   E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E+++  + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E+++  + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C+++ GTC   ++  S   KT +   V  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C+++ GTC   ++ +    K     V ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C +  +I+  F
Sbjct:  407 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMNWFE-KTKATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMSWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMSWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMSWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWFEKTDATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWF 829          

HSP 4 Score: 331.643 bits (849), Expect = 4.634e-96
Identity = 190/431 (44.08%), Postives = 257/431 (59.63%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            + + G Y CCP  +AVCCSD  HCCP    C+++ GTC S   E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E+V   + K  A +  ++ CP G   C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +   V  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C+++ GTC   +E +    K     + ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C +   I+  F
Sbjct:   32 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIIAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIVAWFE-KTEATTLGAVTCPGGQVQCPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEMINWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMNWF 454          

HSP 5 Score: 331.643 bits (849), Expect = 5.665e-96
Identity = 191/431 (44.32%), Postives = 256/431 (59.40%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            + + G Y CCP  +AVCCSD  HCCP    C+++ GTC S   E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E+V   + K  A+++ +V CP  Q QC DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +   +  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C+++ GTC   +E +    K     V ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C +   +C +   I+  F
Sbjct:  107 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTC-SQGSEIVAWFE-KTEATTLGAVTCPGGQVQCPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEMINWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKT-EATTLGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMNWFEKTKATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMSWF 529          

HSP 6 Score: 328.561 bits (841), Expect = 6.186e-95
Identity = 182/424 (42.92%), Postives = 246/424 (58.02%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            + + G Y CCP  +AVCCSD  HCCP    C++  GTC       +     K  A+++++V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC    + +    K +  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C+++ GTC   ++  +   KT +   V  V CPG + +C DG TCC L +G  YGCCP   A CCSD +HCCP    C++  GTC   +  +    K     + ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C + 
Sbjct: 1082 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQ--GSAIINWFEKTEATTLVTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMAWFEKTETEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSEIMAWFEKT-EATTVGTVTCPGGQSECPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSAIINWFEKTEATTLVTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQG 1499          

HSP 7 Score: 301.212 bits (770), Expect = 1.449e-85
Identity = 170/380 (44.74%), Postives = 229/380 (60.26%), Query Frame = 3
Query:  414 KVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN--ILLKF 1532
            K  A+++ +V+CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT +   +  V CPG + QC DG TCC L +G  YGCCP   A CCSD +HCCP    C+++ GTC   +E +    K     V ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C ++  +C +   I+  F
Sbjct:    6 KTEATTLGAVICPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIIAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIVAWFEKT-EATTLGAVTCPGGQVQCPDGNTCCLLSSGQ-YGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEMINWFEKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWF 379          

HSP 8 Score: 291.197 bits (744), Expect = 4.115e-82
Identity = 181/448 (40.40%), Postives = 251/448 (56.03%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT---------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPIL-------VESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINF 1547
            + + G Y CCP  +AVCCSD  HCCP    C+++ GTC S   +++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  +++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   KT          Q + VN  +           +T   L +   YGCCP   A CCSD +HCCP    C++ +    H  +  E+++ P L       V ++ CP G S C    TCC  ++  Y CCP PNAVCCSDH HCCPN  +C +   +C +       IIN+
Sbjct:  707 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTDATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTDATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTC-SQGSEIMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTCSQGSEIMAWFEKTEATTLEQLHVQEDKVNVQM-----------ETHVVLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVLEA---HVVK--EVRLWPGLKKTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVAGGTCSQGSA----IINW 1128          

HSP 9 Score: 287.345 bits (734), Expect = 1.030e-80
Identity = 173/431 (40.14%), Postives = 241/431 (55.92%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--KISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538
            + + G Y CCP  +AVCCSD  HCCP    C+++ GTC S   E +   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A+++ +V CP  QS+C DG+TCC +  G Y CCP  +AVCCSD  HCCP    C++  GTC S+  E++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCCSD L CCP    C++S GTC   ++  +   K  QP  + ++     K Q   G         ++Y    +  A CCSD +HCCP    C+++ GTC   ++ +    K     + ++ CP G S C    TCC  ++  Y CCP PNAVCC D SHCCP+   C+   ++C +       I
Sbjct: 1459 LLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSETMAWFE-KTEATTVGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIINWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLFSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMAWFEKMKQP-LLEQLRVRRTKKQ--KGVWIIANEIFETY----WQLAVCCSDHLHCCPNGYTCDVSGGTCSQGSDIMNWFEKTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPVPNAVCCEDGSHCCPSGYRCNAQAQTCSRGKHFMAWI 1876          

HSP 10 Score: 256.914 bits (655), Expect = 2.621e-70
Identity = 169/447 (37.81%), Postives = 228/447 (51.01%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC----DHQAEALEIKISPILVESIK---CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FNYY 1568
            G Y CCP  +AVCCSD  HCCP    C+++ GTC S   E++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCCSD  HCCP    C++  GTC    + +    K+K P    L V    +++   G     +         +  AVCCSD  HCCP    C++  GTC S+  +++   + K  A +  ++ CP G S C  G TCCLLS G YGCCP  NAVCC D   CCP    CN  A TC           K+PS  ++         + CP  K  C  G TCC  P  D + CCP S ATCC D+ HCCP+N  C  N   C    D + +    KI     +++K   C +GS C    TCC  +N +++CCP P A CC D  HCCP+   C   + +C    L K P +   P  N++
Sbjct: 1613 GQYGCCPLPNAVCCSDHLHCCPNGYTCDVSGGTC-SQGSEIMAWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPLPNAVCCSDHLHCCPNGYTCDVSQGTCSQGSEIMAWFEKMKQPLLEQLRV---RRTKKQKGV---WIIANEIFETYWQLAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPVPNAVCCEDGSHCCPSGYRCNAQAQTCSRGKHFMAWIKKEPSKTVQRHPEISSEMITCPDNKTTCPPGCTCC--PFKDEFSCCPTSHATCCPDQAHCCPENFECIDNSTRCRAKSDKRIQEALKKIPGKKHDALKLVQCKDGSSCPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHH 2047          

HSP 11 Score: 235.343 bits (599), Expect = 5.395e-63
Identity = 167/444 (37.61%), Postives = 231/444 (52.03%), Query Frame = 3
Query:  294 YSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD------SKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS---IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--TKKPSL----LIKTFQPNPVN-RVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI-KISPIL----VESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            +  AVCCSD  HCCP    C+++ GTC S   +++   + K  A+++ +V CP  QS+C DG+TCC ++ G Y CCP  +AVCC D  HCCP    CN  A TC       + +K+  +K   + P  S   + CPD ++ C  G TCC      ++CCP S A CC D+ HCCP+N  C  ++  C +K  + + +   KIP   + +   ++C DGSS C   +TCC+ S+G++ CCP   A CC DK+ CCP    C   + TC S   TK PS+     +    P+ +     C   K  C +  TCC+  +G S+GCCP   A CC D  HCCP    C++   TC   +  +   K  P L     E I CP+    C    TCC   +D Y CCP+ NAVCC D  HCCPN  +C  +T SC KN     P+    P
Sbjct: 1765 WQLAVCCSDHLHCCPNGYTCDVSGGTC-SQGSDIMNWFE-KTEATTLGTVTCPGGQSECPDGNTCCLLSSGQYGCCPVPNAVCCEDGSHCCPSGYRCNAQAQTCSRGKHFMAWIKKEPSKTVQRHPEISSEMITCPDNKTTCPPGCTCCPFKD-EFSCCPTSHATCCPDQAHCCPENFECIDNSTRCRAKSDKRIQEALKKIPGKKHDALKLVQCKDGSS-CPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHHHPSTLALNKTCRDGKSSCPEAFTCCEEKSG-SFGCCPLKDAVCCKDHQHCCPSGYKCDVVHATCQKGSSNVTWSKKLPSLPSKKSEDITCPDMYQSCPSNTTCCRITDDLYGCCPHANAVCCDDGKHCCPNGFTCDASTGSC-KNEEENIPVSKKFP 2202          

HSP 12 Score: 172.555 bits (436), Expect = 1.008e-41
Identity = 106/279 (37.99%), Postives = 146/279 (52.33%), Query Frame = 3
Query:  276 SYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA---SSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS-KLKEVVTKMKLKV-----PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL-KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKK 1079
             +SCCP S A CC D+ HCCP+N EC  N   C +   + + +   K+P     ++  V C D S C   STCC  + G++ACCP   A CC DK HCCP    C   + TC S  L ++ +  K+       P++  L+  C D +S C +  TCC    GS+ CCP   AVCC D +HCCP    C++   TC      V    KL  +P+  +  I CPD   +C +  TCC ++D  YGCCP +NAVCC D   CCP    C+ S G+C ++ + 
Sbjct: 1916 EFSCCPTSHATCCPDQAHCCPENFECIDNSTRCRAKSDKRIQEALKKIPGKKHDALKLVQCKDGSSCPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHHHPSTLALNKTCRDGKSSCPEAFTCCEEKSGSFGCCPLKDAVCCKDHQHCCPSGYKCDVVHATCQKGSSNVTWSKKLPSLPSKKSEDITCPDMYQSCPSNTTCCRITDDLYGCCPHANAVCCDDGKHCCPNGFTCDASTGSCKNEEEN 2194          

HSP 13 Score: 126.331 bits (316), Expect = 1.749e-26
Identity = 86/245 (35.10%), Postives = 125/245 (51.02%), Query Frame = 3
Query:  162 REFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV-LKEVVTKIKLKV-----PASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL-KVPASSILSVVCPDQSQ-CNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL 869
            +E +K I        K+V C D S C   S+CC+ ++G+++CCP   A CC DK HCCP   +C     TC S  L ++ +  K+       P++  L+  C D +S C +  TCC    GS+ CCP   AVCC D +HCCP    C++   TC      V    KL  +P+     + CPD  Q C   +TCC +    Y CCP+++AVCC D +HCCP    C+   G+C ++ + +    K 
Sbjct: 1957 QEALKKIPGKKHDALKLVQCKDGSSCPADSTCCMQSNGAFACCPLPQATCCPDKIHCCPHGFKCYDQSSTCLSGNLTKIPSVAKIPTLNHHHPSTLALNKTCRDGKSSCPEAFTCCEEKSGSFGCCPLKDAVCCKDHQHCCPSGYKCDVVHATCQKGSSNVTWSKKLPSLPSKKSEDITCPDMYQSCPSNTTCCRITDDLYGCCPHANAVCCDDGKHCCPNGFTCDASTGSCKNEEENIPVSKKF 2201          
BLAST of Granulin b vs. Ensembl Cavefish
Match: grnb (granulins-like [Source:NCBI gene;Acc:103046308])

HSP 1 Score: 277.33 bits (708), Expect = 6.401e-84
Identity = 182/469 (38.81%), Postives = 239/469 (50.96%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKIPA-ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-----YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            T  G Y CCP  +A CCSD  HCC + T C+L    C   +   + V ++ ++ P S   +VVCPDQ S+C D +TCC +  GS+ CCP  +AVCC DK HCCPQ T C+L    C S +   V  ++ K PA                      V CPD+ S C D +TCC +  GSY CCP   AVCCSD  HCCPQ T C+L    C S   L+ V T +   +   ++  S+ C + S  C++G+TCC   DG + CCP   AVCC D + CCPQ TVC  S  TC +     +L+    +   +NRV  P  +       C  G TCCK+ +G ++GCCP   A CC D +HCCP+NTVCN+  GTCD        ++S   V             +C   S C    TCC   + +++CCP P AVCC DH HCCP    C +  +SCD   L         P
Sbjct:   35 TPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQP-SLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPC-NESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARS--TCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESG-TWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQP 497          

HSP 2 Score: 264.233 bits (674), Expect = 5.396e-79
Identity = 186/474 (39.24%), Postives = 234/474 (49.37%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKVPAS-SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK--IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS--LLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ--AEALEIKISPIL---------------------VES-IKCPNGSLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            DGS+ CCP  +AVCC DK HCCPQ T C+L    C S +   V  ++ K PA                      V CPD+ S C D +TCC +  GSY CCP   AVCCSD  HCCPQ T C+L    C S   L+ V T +   V    ++ SV C +   C  GSTCC    G +ACCP   AVCC D  HCCPQ TVC        + L  +V  ++ K  I  +   + E  D ++TC  GATCC +  G++GCCP   AVCC D L CCP+NTVCN++AGTCDS     +  L +   +  P   +  P A  QC +      G TCC+  +G ++ CCP   A CC D  HCCPQ   C+I   +CDH      L  K  P L                     VES  KC   + C +  TCC     + + CCP P AVCC D  HCCPN+ +C     +C K  L
Sbjct:  115 DGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSL--PPANDQCDETSACPTGTTCCRQKSG-AWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTCLKGHL 584          

HSP 3 Score: 247.284 bits (630), Expect = 9.329e-73
Identity = 159/414 (38.41%), Postives = 211/414 (50.97%), Query Frame = 3
Query:  438 SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSI-LSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-----------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--------TKKPSLLIK-TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE-----SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFHP 1553
            +++CPD   C+DG+TCC    G Y CCP  +A CCSD  HCC + T+C+L+   C +K   +   M++ +   S+  +VVCPDQ S+C D +TCC +  GS+ CCP  +AVCC DK HCCPQ T C+L    C S +   V  ++ K PA                      ++CPD  S C    TCC L +GSYGCCP   AVCCSD + CCPQ T C+L+   C S            P + +K T +  P N  +       C  G TCCK   GD + CCP   A CC D IHCCPQ TVC   + TC   A+ L     ++  P +       + KC   + C +  TCC   + ++ CCP P AVCC DH HCCP NT C++   +CD         L  P +   P
Sbjct:   17 ALICPDGGMCDDGNTCCQTPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQPSLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESV------ACESGSTCCKTKDGD-WACCPLPEAVCCEDHIHCCPQGTVC--ARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTP 420          

HSP 4 Score: 240.35 bits (612), Expect = 4.226e-70
Identity = 157/468 (33.55%), Postives = 224/468 (47.86%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KVPASSI--LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP--------------------DGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ------------PNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            T DG ++CCP   AVCC D  HCCPQ T C  +     + L  +V  ++ K   + +    +  C   + C  G+TCC +  G++ CCP   AVCC D  HCCP+NTVCN+ AGTCDS       ++ +    K PA+S+   +  C + S C  G+TCC    G++ACCP   AVCC D  HCCPQ   C++   +CD      +   K K PA+ +++ +                      D  ++C    TCC +     +GCCP   AVCC D   CCP +  C+ +  TC     K  L I  F+             + V  V C  +  +C  G TCC+L  G  +GCCP+  A CC D +HCCP    C++  GTC   +    + ++ +     E + C   S C +  TCC  ++  ++CCP+  AVCC D  HCCP    C    K C +   L +
Sbjct:  285 TKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFK-KQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTC----LKGHLEIPWFKKQEAKVTQGSEVAHGVADVQC-DSTARCPTGSTCCRLTTG-QWGCCPHVQAVCCDDHVHCCPAGYTCDLQAGTCLRTSTLHTVALTLVHTHTKEQVMCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDPKAKGCARATSLTW 745          
BLAST of Granulin b vs. Ensembl Cavefish
Match: grnb (granulins-like [Source:NCBI gene;Acc:103046308])

HSP 1 Score: 277.33 bits (708), Expect = 6.401e-84
Identity = 182/469 (38.81%), Postives = 239/469 (50.96%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC--DSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKIPA-ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK-----YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESI----------KCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            T  G Y CCP  +A CCSD  HCC + T C+L    C   +   + V ++ ++ P S   +VVCPDQ S+C D +TCC +  GS+ CCP  +AVCC DK HCCPQ T C+L    C S +   V  ++ K PA                      V CPD+ S C D +TCC +  GSY CCP   AVCCSD  HCCPQ T C+L    C S   L+ V T +   +   ++  S+ C + S  C++G+TCC   DG + CCP   AVCC D + CCPQ TVC  S  TC +     +L+    +   +NRV  P  +       C  G TCCK+ +G ++GCCP   A CC D +HCCP+NTVCN+  GTCD        ++S   V             +C   S C    TCC   + +++CCP P AVCC DH HCCP    C +  +SCD   L         P
Sbjct:   35 TPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQP-SLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPC-NESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARS--TCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESG-TWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQP 497          

HSP 2 Score: 264.233 bits (674), Expect = 5.396e-79
Identity = 186/474 (39.24%), Postives = 234/474 (49.37%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-----------------VVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKVPAS-SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK--IPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS--LLIKTFQPNPVNRVICPGAKYQCSD------GQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQ--AEALEIKISPIL---------------------VES-IKCPNGSLCGQKGTCCPSAN-DSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            DGS+ CCP  +AVCC DK HCCPQ T C+L    C S +   V  ++ K PA                      V CPD+ S C D +TCC +  GSY CCP   AVCCSD  HCCPQ T C+L    C S   L+ V T +   V    ++ SV C +   C  GSTCC    G +ACCP   AVCC D  HCCPQ TVC        + L  +V  ++ K  I  +   + E  D ++TC  GATCC +  G++GCCP   AVCC D L CCP+NTVCN++AGTCDS     +  L +   +  P   +  P A  QC +      G TCC+  +G ++ CCP   A CC D  HCCPQ   C+I   +CDH      L  K  P L                     VES  KC   + C +  TCC     + + CCP P AVCC D  HCCPN+ +C     +C K  L
Sbjct:  115 DGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESVACESGSTCCKTKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSL--PPANDQCDETSACPTGTTCCRQKSG-AWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFKKQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTCLKGHL 584          

HSP 3 Score: 247.284 bits (630), Expect = 9.329e-73
Identity = 159/414 (38.41%), Postives = 211/414 (50.97%), Query Frame = 3
Query:  438 SVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSI-LSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-----------------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK--------TKKPSLLIK-TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVE-----SIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-----LLKFPIINFHP 1553
            +++CPD   C+DG+TCC    G Y CCP  +A CCSD  HCC + T+C+L+   C +K   +   M++ +   S+  +VVCPDQ S+C D +TCC +  GS+ CCP  +AVCC DK HCCPQ T C+L    C S +   V  ++ K PA                      ++CPD  S C    TCC L +GSYGCCP   AVCCSD + CCPQ T C+L+   C S            P + +K T +  P N  +       C  G TCCK   GD + CCP   A CC D IHCCPQ TVC   + TC   A+ L     ++  P +       + KC   + C +  TCC   + ++ CCP P AVCC DH HCCP NT C++   +CD         L  P +   P
Sbjct:   17 ALICPDGGMCDDGNTCCQTPSGGYGCCPLPNAECCSDHLHCCHEGTLCDLEHSKCVNKTHTLDWVMRVPIRQPSLPQAVVCPDQESECPDDTTCCQLPDGSWGCCPMPNAVCCEDKMHCCPQGTTCDLPHSKCVSSMLGSV-PLRRKFPAYKRAEWKARKDSNGLDLADSNDVDCPDKVSFCPDDTTCCPLGNGSYGCCPMPKAVCCSDHVHCCPQGTSCDLAHSKCVSSNVLEPVTTNLSPVVRVKVTVESVPCNESV------ACESGSTCCKTKDGD-WACCPLPEAVCCEDHIHCCPQGTVC--ARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTP 420          

HSP 4 Score: 240.35 bits (612), Expect = 4.226e-70
Identity = 157/468 (33.55%), Postives = 224/468 (47.86%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL----KVPASSI--LSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP--------------------DGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQ------------PNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            T DG ++CCP   AVCC D  HCCPQ T C  +     + L  +V  ++ K   + +    +  C   + C  G+TCC +  G++ CCP   AVCC D  HCCP+NTVCN+ AGTCDS       ++ +    K PA+S+   +  C + S C  G+TCC    G++ACCP   AVCC D  HCCPQ   C++   +CD      +   K K PA+ +++ +                      D  ++C    TCC +     +GCCP   AVCC D   CCP +  C+ +  TC     K  L I  F+             + V  V C  +  +C  G TCC+L  G  +GCCP+  A CC D +HCCP    C++  GTC   +    + ++ +     E + C   S C +  TCC  ++  ++CCP+  AVCC D  HCCP    C    K C +   L +
Sbjct:  285 TKDGDWACCPLPEAVCCEDHIHCCPQGTVCARSTCVASADLLTLVRWVEKKPTINRVPQPANEKCDPTTTCPKGATCCKMESGTWGCCPLPQAVCCEDHLHCCPRNTVCNVAAGTCDSAFSGTAGQLSVPWVRKTPATSLPPANDQCDETSACPTGTTCCRQKSGAWACCPLPQAVCCDDHEHCCPQGYKCDIIHESCDHPFLPSMLWFK-KQPALQSMTQQSNANAKAIAESAVADVESKHKCDAQTSCPRDNTCCYMKKFNKWGCCPLPEAVCCGDGDHCCPNSYTCDTTKNTC----LKGHLEIPWFKKQEAKVTQGSEVAHGVADVQC-DSTARCPTGSTCCRLTTG-QWGCCPHVQAVCCDDHVHCCPAGYTCDLQAGTCLRTSTLHTVALTLVHTHTKEQVMCDATSHCTESQTCCKLSDTEWACCPFKQAVCCKDMKHCCPVGYVCDPKAKGCARATSLTW 745          
BLAST of Granulin b vs. Ensembl Cavefish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 264.233 bits (674), Expect = 5.242e-79
Identity = 178/497 (35.81%), Postives = 233/497 (46.88%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC-----------------------------------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTK--MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---LEIKIS-PI----------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            TTDG + CCP   AVCC+DK HCCP+N+ C++N   C                                          + LK   T        S++ +V C D   C DG+TCC    G ++CCP   AVCC D  HCCP    CNL AG C+        LK+V ++   + K+P + + +V C D + C D +TCC  + G + CCP   AVCC D  HCCP    CNL AGTC+     V    KL        K+P     ++ C D ++ C    TCC  S+G + CCP   AVCC D   CCP    CN++AGTC+  +       K PS  I   +   V     P  A + C D  TCCK   G  + CCP   A CC D +HCCP    CN+   TCD  + +   LE K S PI             ++ C +   C    TCC   N  +SCCP+P  VCC D  HCCP++ +C+L T +CDKN
Sbjct:  188 TTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCND-TAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKG-GWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKN 682          

HSP 2 Score: 228.024 bits (580), Expect = 1.404e-65
Identity = 156/482 (32.37%), Postives = 217/482 (45.02%), Query Frame = 3
Query:  279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------------------DSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTK--MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            Y CCP +  + C+D+ HCCP + EC+ +  +C          +K   P      V+CPD  S+C   +TCC    G + CCP   AVCC+DK HCCP+N+VC++++  C                                          + LK   T        S++ +V C D   C DG+TCC    G ++CCP   AVCC D  HCCP    CNL AG C+        LK+V ++   + K+P     ++ C D ++ C    TCC  S+G + CCP   AVCC D + CCP    CNL+AGTC+  +      +K     P+     P  K           C D  TCCK   G+ + CCP   A CC D  HCCP    CN+  GTC+  + ++              K+  +    + C     C  + TCC +    +SCCP P AVCC D  HCCP+   C+L   +CD
Sbjct:  132 YGCCPVTQGIVCADRNHCCPNDHECSADSISC----------VKKAEP------VMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCND-TAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGS-VPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCD 594          

HSP 3 Score: 224.557 bits (571), Expect = 2.243e-64
Identity = 156/447 (34.90%), Postives = 211/447 (47.20%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTK--IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKS 1505
            +G +SCCP   AVCC D  HCCP   +CNL  G C+        LK+V ++   + K+P + + +V C D + C D +TCC  + G + CCP   AVCC D  HCCP    CNL AGTC+     V    KL        K+P + + +V C D + C D +TCC  + G + CCP   AVCC D +HCCP    CN+ AGTC+     V    K+        K+P +    + C + +  C+  +TCC    G + CCP   AVCC D L CCP    CNL+A TCD  +       KKPS  I    K         V C  + + C    TCCK      + CCP+    CC D+IHCCP +  CN+   TCD    ++       +   +K        +K      AN+          V C DH H CP+ T+C    K+
Sbjct:  307 EGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPC-NATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHF-CPASSTCCK-DVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVP------MAGPVKASGPPPPEKKKPKENKANE---------PVKCDDH-HSCPDQTTCCFMNKT 734          

HSP 4 Score: 205.682 bits (522), Expect = 1.544e-57
Identity = 148/495 (29.90%), Postives = 211/495 (42.63%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS---------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE-----------------------VVTKMKLKIPAISN------------------LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            V + G Y+CCP+    CC D  HCCP    C   +  C +    +      + PA + L+               ++CPD S C    +C  +    Y CCP +  + C+D+ HCCP +  C+ D+ +C  K +                 V+CPD  S+C   +TCC    G + CCP   AVCC+DK HCCP+N+VC++++  C S   +                       V  K+  K P  S                    ++ C D +  C  G TCC   +G + CCP   AVCC D L CCP    CNL AG C+  +     L K     P+     P  K           C D  TCCK   G+ + CCP   A CC D IHCCP    CN+  GTC+  + ++              K+    V ++ C + + C  + TCC  +   + CCP P AVCC D  HCCP+   C++   +C+
Sbjct:   38 VLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSL--SWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLT-DKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE----------------PVMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWL-KKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCE 510          

HSP 5 Score: 192.971 bits (489), Expect = 6.099e-53
Identity = 138/445 (31.01%), Postives = 200/445 (44.94%), Query Frame = 3
Query:  393 VVTKIKLKVPASSILSVV----CPDQSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------DSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF-----------------------QP-------------------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL------------EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            ++T +KL V A ++L +V    CP+Q  C D  TCC V + G Y CCP+    CC D  HCCP   +C      C          + K  +       ++ +SS  +   ++CPD S C    +C  +    Y CCP +  + C+D+ HCCP +  C+ D+ +C  K + V+                CPDG S C    TCC  +DG +GCCP   AVCC+DK+ CCP+N+VC++++  C S T K   +   F                       QP                   + V  V C      C+DG TCCK   G  + CCP   A CC D +HCCP    CN+  G C+  + ++            E K+    V ++ C + + C  + TCC  +   + CCP P AVCC D  HCCP+   C+L   +C+
Sbjct:    2 LLTMLKLMV-ALALLGLVTGTQCPNQQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLTD-KYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAEPVM----------------CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEG-GWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCE 426          

HSP 6 Score: 178.718 bits (452), Expect = 7.861e-48
Identity = 110/294 (37.41%), Postives = 138/294 (46.94%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT 1073
            ++G + CCP   AVCC D  HCCP   +CNL  GTC+     V    KL        K+P + + +V C D + C D +TCC  + G + CCP   AVCC D +HCCP    CN+ AGTC+     V    K+        K+P      V C     C D STCC    G ++CCP   AVCC D  HCCP    CNL A TCD     +    K     I   + E           D S  C   +TCC   +  + CCPF   VCC D++ CCP +  CNL   TCD  T
Sbjct:  390 SEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNT 683          

HSP 7 Score: 128.257 bits (321), Expect = 7.480e-31
Identity = 86/260 (33.08%), Postives = 112/260 (43.08%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDS----------KLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA------------ISNLSIECPDGSSTCKTGATCCLLS 956
            ++G + CCP   AVCC D QHCCP   +CN+  GTC+     V    K+        K+P      V C     C D STCC    G ++CCP   AVCC D  HCCP    CNL A TCD           K    +     +   ++  +V C     C   STCC      ++CCP+   VCC D+ HCCP +  CNL   TCD     V     +K                +N  ++C D  S C    TCC ++
Sbjct:  474 SEGEWKCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVPMAGPVKASGPPPPEKKKPKENKANEPVKCDDHHS-CPDQTTCCFMN 732          

HSP 8 Score: 117.472 bits (293), Expect = 3.199e-27
Identity = 87/255 (34.12%), Postives = 130/255 (50.98%), Query Frame = 3
Query:  849 VVTKMKLKIPAISNLSI----ECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPS--LLIKTFQ---PNPVNR--VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            ++T +KL + A++ L +    +CP+    C    TCC +LS G Y CCPF    CC D L CCP   +C  +   C + T       +KP+   L K+F+    +  N+  +ICP     C    +C KL   D YGCCP +    C+D+ HCCP +  C+ +  +C  +AE       P++     CP+G S C  + TCCP+ +  + CCP P AVCC+D  HCCP N+ C +N+  C  +   + P+    P
Sbjct:    2 LLTMLKLMV-ALALLGLVTGTQCPN-QQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPD-NSSCPPEFSCLKL--TDKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE-------PVM-----CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFP 239          
BLAST of Granulin b vs. Ensembl Cavefish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 261.151 bits (666), Expect = 7.135e-78
Identity = 177/497 (35.61%), Postives = 226/497 (45.47%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC-----------------------------------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---LEIKIS-PI----------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            TTDG + CCP   AVCC+DK HCCP+N+ C++N   C                                          + LK   T        S++ +V C D   C DG+TCC    G ++CCP   AVCC D  HCCP    CNL AGTC+     V    KL        K+P + + +V C D + C D +TCC  + G + CCP   AVCC D  HCCP    CNL AGTC+     V    K+        K+P      + C D +  C    TCC    G + CCP   AVCC D   CCP    CN++AGTC+  +       K PS  I   +   V     P  A + C D  TCCK   G  + CCP   A CC D +HCCP    CN+   TCD  + +   LE K S PI             ++ C +   C    TCC   N  +SCCP+P  VCC D  HCCP++ +C+L T +CDKN
Sbjct:  188 TTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCND-TVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKG-GWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKN 682          

HSP 2 Score: 228.409 bits (581), Expect = 8.797e-66
Identity = 157/482 (32.57%), Postives = 213/482 (44.19%), Query Frame = 3
Query:  279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------------------DSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK---------YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            Y CCP +  + C+D+ HCCP + EC+ +  +C          +K   P      V+CPD  S+C   +TCC    G + CCP   AVCC+DK HCCP+N+VC++++  C                                          + LK   T        S++ +V C D   C DG+TCC    G ++CCP   AVCC D  HCCP    CNL AGTC+     V    KL        K+P     ++ C D ++ C    TCC  S+G + CCP   AVCC D + CCP    CNL+AGTC+  +      +K     P+     P  K           C D  TCCK   G  + CCP   A CC D  HCCP    CN+  GTC+  + ++              K+  +    + C     C  + TCC +    +SCCP P AVCC D  HCCP+   C+L   +CD
Sbjct:  132 YGCCPVTQGIVCADRNHCCPNDHECSADSISC----------VKKAEP------VMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCND-TAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGS-VPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKG-GWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCD 594          

HSP 3 Score: 219.935 bits (559), Expect = 1.186e-62
Identity = 156/447 (34.90%), Postives = 204/447 (45.64%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKS 1505
            +G +SCCP   AVCC D  HCCP   +CNL  GTC+     V    KL        K+P + + +V C D + C D +TCC  + G + CCP   AVCC D  HCCP    CNL AGTC+     V    K+        K+P +    V C D   C D +TCC    G + CCP   AVCC D +HCCP    CN+ AGTC+     V    K+        K+P +    + C + +  C+  +TCC    G + CCP   AVCC D L CCP    CNL+A TCD  +       KKPS  I    K         V C  + + C    TCCK      + CCP+    CC D+IHCCP +  CN+   TCD    ++       +   +K        +K      AN+          V C DH H CP+ T+C    K+
Sbjct:  307 EGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPC-NATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHF-CPASSTCCKD-VNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVP------MAGPVKASGPPPPEKKKPKENKANE---------PVKCDDH-HSCPDQTTCCFMNKT 734          

HSP 4 Score: 203.756 bits (517), Expect = 8.091e-57
Identity = 148/495 (29.90%), Postives = 214/495 (43.23%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS---------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE-----------------------VVTKMKLKIPAISN------------------LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGS--------LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            V + G Y+CCP+    CC D  HCCP    C   +  C +    +      + PA + L+               ++CPD S C    +C  +    Y CCP +  + C+D+ HCCP +  C+ D+ +C  K +                 V+CPD  S+C   +TCC    G + CCP   AVCC+DK HCCP+N+VC++++  C S   +                       V  K+  K P  S                    ++ C D +  C  G TCC   +G + CCP   AVCC D + CCP    CNL+AGTC+  +      +K     P+     P  K           C D  TCCK   G+ + CCP   A CC D IHCCP    CN+  GTC+  + ++    ++   PI  + +    GS         C  + TCC +    ++CCP P AVCC D  HCCP+   C++   +C+
Sbjct:   38 VLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSL--SWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLT-DKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE----------------PVMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGS-VPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCE 510          

HSP 5 Score: 194.512 bits (493), Expect = 2.059e-53
Identity = 139/445 (31.24%), Postives = 200/445 (44.94%), Query Frame = 3
Query:  393 VVTKIKLKVPASSILSVV----CPDQSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------DSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF-----------------------QP-------------------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            ++T +KL V A ++L +V    CP+Q  C D  TCC V + G Y CCP+    CC D  HCCP   +C      C          + K  +       ++ +SS  +   ++CPD S C    +C  +    Y CCP +  + C+D+ HCCP +  C+ D+ +C  K + V+                CPDG S C    TCC  +DG +GCCP   AVCC+DK+ CCP+N+VC++++  C S T K   +   F                       QP                   + V  V C      C+DG TCCK   G  + CCP   A CC D IHCCP    CN+  GTC+  + ++              K+    V ++ C + + C  + TCC  +   + CCP P AVCC D  HCCP+   C+L   +C+
Sbjct:    2 LLTMLKLMV-ALALLGLVTGTQCPNQQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLTD-KYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAEPVM----------------CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEG-GWSCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCE 426          

HSP 6 Score: 172.17 bits (435), Expect = 1.297e-45
Identity = 111/294 (37.76%), Postives = 139/294 (47.28%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTK-IK-LKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT 1073
            ++G + CCP   AVCC D  HCCP   +CNL  GTC+        +K+V ++ IK  K+P +    V C D   C D +TCC    G + CCP   AVCC D +HCCP    CN+ AGTC+     V    K+        K+P      V C     C D STCC    G ++CCP   AVCC D  HCCP    CNL A TCD     +    K     I   + E           D S  C   +TCC   +  + CCPF   VCC D++ CCP +  CNL   TCD  T
Sbjct:  390 SEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKVPSRPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNT 683          

HSP 7 Score: 117.087 bits (292), Expect = 3.407e-27
Identity = 87/255 (34.12%), Postives = 130/255 (50.98%), Query Frame = 3
Query:  849 VVTKMKLKIPAISNLSI----ECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPS--LLIKTFQ---PNPVNR--VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            ++T +KL + A++ L +    +CP+    C    TCC +LS G Y CCPF    CC D L CCP   +C  +   C + T       +KP+   L K+F+    +  N+  +ICP     C    +C KL   D YGCCP +    C+D+ HCCP +  C+ +  +C  +AE       P++     CP+G S C  + TCCP+ +  + CCP P AVCC+D  HCCP N+ C +N+  C  +   + P+    P
Sbjct:    2 LLTMLKLMV-ALALLGLVTGTQCPN-QQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPD-NSSCPPEFSCLKL--TDKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE-------PVM-----CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFP 239          
BLAST of Granulin b vs. Ensembl Cavefish
Match: grna (granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434])

HSP 1 Score: 259.996 bits (663), Expect = 1.793e-77
Identity = 177/497 (35.61%), Postives = 229/497 (46.08%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC-----------------------------------------DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTK--MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLIKTFQPNPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---LEIKIS-PI----------LVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            TTDG + CCP   AVCC+DK HCCP+N+ C++N   C                                          + LK   T        S++ +V C D   C DG+TCC    G ++CCP   AVCC D  HCCP    CNL AG C+        LK+V ++   + K+P + + +V C D + C D +TCC  + G + CCP   AVCC D  HCCP    CNL AGTC+     V    KL        K+P      + C D +  C    TCC    G + CCP   AVCC D   CCP    CN++AGTC+  +       K PS  I   +   V     P  A + C D  TCCK   G  + CCP   A CC D +HCCP    CN+   TCD  + +   LE K S PI             ++ C +   C    TCC   N  +SCCP+P  VCC D  HCCP++ +C+L T +CDKN
Sbjct:  188 TTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPCDDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCND-TVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKG-GWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKN 682          

HSP 2 Score: 219.164 bits (557), Expect = 2.556e-62
Identity = 156/447 (34.90%), Postives = 207/447 (46.31%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS------VLKEVVTK--IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPSLLI----KTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKS 1505
            +G +SCCP   AVCC D  HCCP   +CNL  G C+        LK+V ++   + K+P + + +V C D + C D +TCC  + G + CCP   AVCC D  HCCP    CNL AGTC+     V    KL        K+P +    V C D   C D +TCC    G + CCP   AVCC D +HCCP    CN+ AGTC+     V    K+        K+P +    + C + +  C+  +TCC    G + CCP   AVCC D L CCP    CNL+A TCD  +       KKPS  I    K         V C  + + C    TCCK      + CCP+    CC D+IHCCP +  CN+   TCD    ++       +   +K        +K      AN+          V C DH H CP+ T+C    K+
Sbjct:  307 EGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPC-NATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHF-CPASSTCCK-DVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNTTSVP------MAGPVKASGPPPPEKKKPKENKANE---------PVKCDDH-HSCPDQTTCCFMNKT 734          

HSP 3 Score: 202.601 bits (514), Expect = 2.470e-56
Identity = 149/495 (30.10%), Postives = 212/495 (42.83%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS---------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKE-----------------------VVTKMKLKIPAISN------------------LSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKY---------QCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL----EIKISPILVESIKCPNGS--------LCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            V + G Y+CCP+    CC D  HCCP    C   +  C +    +      + PA + L+               ++CPD S C    +C  +    Y CCP +  + C+D+ HCCP +  C+ D+ +C  K +                 V+CPD  S+C   +TCC    G + CCP   AVCC+DK HCCP+N+VC++++  C S   +                       V  K+  K P  S                    ++ C D +  C  G TCC   +G + CCP   AVCC D L CCP    CNL AG C+  +     L K     P+     P  K           C D  TCCK   G+ + CCP   A CC D IHCCP    CN+  GTC+  + ++    ++   PI  + +    GS         C  + TCC +    ++CCP P AVCC D  HCCP+   C++   +C+
Sbjct:   38 VLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSL--SWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLT-DKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE----------------PVMCPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEGGWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWL-KKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGE-WKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCE 510          

HSP 4 Score: 192.586 bits (488), Expect = 7.961e-53
Identity = 138/445 (31.01%), Postives = 200/445 (44.94%), Query Frame = 3
Query:  393 VVTKIKLKVPASSILSVV----CPDQSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------DSKLKEVVTKMKLKVPASSILS---VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF-----------------------QP-------------------NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL------------EIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD 1511
            ++T +KL V A ++L +V    CP+Q  C D  TCC V + G Y CCP+    CC D  HCCP   +C      C          + K  +       ++ +SS  +   ++CPD S C    +C  +    Y CCP +  + C+D+ HCCP +  C+ D+ +C  K + V+                CPDG S C    TCC  +DG +GCCP   AVCC+DK+ CCP+N+VC++++  C S T K   +   F                       QP                   + V  V C      C+DG TCCK   G  + CCP   A CC D +HCCP    CN+  G C+  + ++            E K+    V ++ C + + C  + TCC  +   + CCP P AVCC D  HCCP+   C+L   +C+
Sbjct:    2 LLTMLKLMV-ALALLGLVTGTQCPNQQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPDNSSCPPEFSCLKLTD-KYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAEPVM----------------CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFPARLRADWENHRPVAVTPKLTNKQPKTSTALKSTTTNKTRNATVSTVYNVPC-DDTVACADGTTCCKNGEG-GWSCCPLPQAVCCDDFLHCCPHGKKCNLIAGKCEDPSGSVPWLKKVPSRPIREKKLPETKVYNVPCNDTAACPDETTCCKDSEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCE 426          

HSP 5 Score: 173.326 bits (438), Expect = 5.885e-46
Identity = 110/294 (37.41%), Postives = 134/294 (45.58%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKL--------KVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP---------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT 1073
            ++G + CCP   AVCC D  HCCP   +CNL  GTC+     V    KL        K+P +    V C D   C D +TCC    G + CCP   AVCC D +HCCP    CN+ AGTC+     V    K+        K+P      V C     C D STCC    G ++CCP   AVCC D  HCCP    CNL A TCD     +    K     I   + E           D S  C   +TCC   +  + CCPF   VCC D++ CCP +  CNL   TCD  T
Sbjct:  390 SEGEWKCCPLPQAVCCDDFIHCCPHGKKCNLAAGTCEDPSGSVPWMKKLPSQPIKGKKLPETKGSDVPCNDTVACPDETTCCKNVKGGWNCCPLPQAVCCDDFQHCCPHGKKCNVAAGTCEDPSGSVPWIKKVPSRPISGKKLPKVKGAGVPCNATFACEDESTCCKNDKGGWSCCPLPEAVCCEDFLHCCPHGKKCNLAAMTCDDPSGSIPWLEKKPSRPIGGQNKEKGKAAAANVSCDSSHFCPASSTCCKDVNAEWSCCPFPQGVCCEDRIHCCPHDATCNLRTLTCDKNT 683          

HSP 6 Score: 117.087 bits (292), Expect = 3.628e-27
Identity = 87/255 (34.12%), Postives = 130/255 (50.98%), Query Frame = 3
Query:  849 VVTKMKLKIPAISNLSI----ECPDGSSTCKTGATCC-LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKT-------KKPS--LLIKTFQ---PNPVNR--VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            ++T +KL + A++ L +    +CP+    C    TCC +LS G Y CCPF    CC D L CCP   +C  +   C + T       +KP+   L K+F+    +  N+  +ICP     C    +C KL   D YGCCP +    C+D+ HCCP +  C+ +  +C  +AE       P++     CP+G S C  + TCCP+ +  + CCP P AVCC+D  HCCP N+ C +N+  C  +   + P+    P
Sbjct:    2 LLTMLKLMV-ALALLGLVTGTQCPN-QQLCGDKHTCCQVLSSGEYNCCPFPQGECCEDHLHCCPAGMLCQTAESKCQNSTHSLSWTERKPAQAYLAKSFRMISSSTANKDNIICPD-NSSCPPEFSCLKL--TDKYGCCPVTQGIVCADRNHCCPNDHECSADSISCVKKAE-------PVM-----CPDGVSECPVQTTCCPTTDGGWGCCPMPRAVCCADKVHCCPENSVCHVNSSKCVSSTNKELPMWAKFP 239          
BLAST of Granulin b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009302.1 (pep scaffold:Pmarinus_7.0:GL483232:1183:11161:1 gene:ENSPMAG00000008413.1 transcript:ENSPMAT00000009302.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 314.309 bits (804), Expect = 1.296e-98
Identity = 192/444 (43.24%), Postives = 233/444 (52.48%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKI-SPILV-----ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            T  G ++CCP   AVCC D +HCCPQ T CNL   TCD     +      K PA  +      V+C DQS C DG+TCC   GG +ACCP   AVCC D  HCCPQ T CNL A TCD     +      K PA  +      V+C DQS C DG+TCC +  G + CCP   AVCC D +HCCP+ T CNL    CD     +    K   L++    N+ I   D   +C  G TCC L  G +GCCP   AVCC D   CCPQ T CNL A TCD         TK P+L +        N VIC   ++ C DG TCCK+P+GD +GCCP   A CC D  HCCPQ T CN+   TCD  A +L     +P L        +KC +   C  + TCC +    + CCP   AVCC DH HCCP  T+C++   SCD+  L
Sbjct:  229 TPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQ--GTLSLPWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSL--PWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSLPWSTKTPALRVAGEPNVVIC--DDQFSCPDGNTCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVA----GEPNVVIC-DDQFSCPDGDTCCKMPSGD-WGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGALSLPWSTKTPALRVAGEPNDVKCDDQVSCPDQTTCCKTGTGDWGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSCDQGQL 660          

HSP 2 Score: 309.686 bits (792), Expect = 8.411e-97
Identity = 191/451 (42.35%), Postives = 232/451 (51.44%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            +   G + CCP   AVCC DK+HCCP+ T CN+   TC+     +      K PA  +      V C D   C DG+TCC   GG +ACCP   AVCC D  HCCPQ T CNL A TCD     +      K PA  +      V+C DQS C DG+TCC   GG +ACCP   AVCC D  HCCPQ T CNL A TCD     +    K   L++    N+ I   D  S+C  G TCC +  G +GCCP   AVCC D   CCP+ T CNL    CD         TK P+L +        N VIC   ++ C DG TCCKLP+GD +GCCP   A CC D  HCCPQ T CN+   TCD          +  AL +   P +V   +   CP+G       TCC   +  + CCP   AVCC DH HCCP  T+C+L  ++CDK  L
Sbjct:  150 ILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALSL--PWSTKTPALRMTGEPNDVQCDDLVGCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSL--PWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVIC--DDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSLPWSTKTPALRVA----GEPNVVIC-DDQFSCPDGNTCCKLPSGD-WGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVICDDQFSCPDGD------TCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGAL 582          

HSP 3 Score: 286.96 bits (733), Expect = 3.714e-88
Identity = 183/454 (40.31%), Postives = 227/454 (50.00%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPV---NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL--------EIKISPILVES-------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            T  G ++CCP   AVCC D +HCCPQ T CNL   TCD     +      K PA  +      V+C DQS C DG+TCC +  G + CCP   AVCC D +HCCP+ T CNL    CD     +      K PA  +      V+C DQ  C DG+TCC +  G + CCP   AVCC D  HCCPQ T CNL A TCD     +    K   L++    N+ I   D   +C  G TCC +  G +GCCP   AVCC D   CCPQ T CNL A TCD         TK P+L +   +PN V   ++V CP       D  TCCK   GD +GCCP   A CC D  HCCP+ T CN+  G+CD    +L          +++ +L  S       ++C +   C    TCC      + CCP P A CCSD  HCCP+  +C L   SC K 
Sbjct:  307 TPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQ--GTLSLPWSTKTPALRVAGEPNVVICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSL--PWSTKTPALRVAGEPNVVICDDQFSCPDGNTCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVIC--DDQFSCPDGDTCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGALSLPWSTKTPALRV-AGEPNDVKCDDQVSCP-------DQTTCCKTGTGD-WGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSCDQGQLSLPWSSKTPARTRLTALLPASAAARGGSVRCDSAYACPDGTTCCQLPQGQWGCCPLPLATCCSDFVHCCPSGYTCDLAQASCIKK 745          

HSP 4 Score: 283.878 bits (725), Expect = 5.115e-87
Identity = 182/444 (40.99%), Postives = 228/444 (51.35%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS-VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILV---ESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
            G Y CC    AVCCSD  HCCP+NT C+L  G C  V  ++      K P+    S V C   + C+D +TCC +  G + CCP   AVCC DK HCCP+ T+CN+ + TC+     +      K PA  +      V C D   C DG+TCC   GG +ACCP   AVCC D  HCCPQ T CNL A TCD     +    K   L++    N+ I   D  S+C  G TCC    G + CCP   AVCC D   CCPQ T CNL A TCD         TK P+L +        N VIC   +  C DG TCCK+P+GD +GCCP   A CC D  HCCP+ T CN+    CD          +  AL +   P +V   +   CP+G+      TCC   +  + CCP   AVCC DH HCCP  T+C+L  ++CD+  L
Sbjct:   79 GQYGCCSLEDAVCCSDYLHCCPKNTMCDLKLGKC--VHGKLSIPWVSKYPSKQAASDVQCDAFTSCSDQNTCCILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALSL--PWSTKTPALRMTGEPNDVQCDDLVGCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVVIC--DDQSSCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVA----GEPNVVIC-DDQSSCPDGNTCCKMPSGD-WGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTLSLPWSTKTPALRVAGEPNVVICDDQFSCPDGN------TCCKLPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTL 504          

HSP 5 Score: 263.848 bits (673), Expect = 1.664e-79
Identity = 177/440 (40.23%), Postives = 219/440 (49.77%), Query Frame = 3
Query:  300 SAVCCSDKQHCCPQNTECNLNKGTCDS--VLKEVVTKIKLKVPASSILSVV---------CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-DSKLK-EVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS-------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNIL 1523
             AVCCSD  HCCP  T C+L  G C    +    + K     P +    +          CPD + C D +TCC +A G Y CC    AVCCSD  HCCP+NT+C+L  G C   KL    V+K   K  AS    V C   + C+D +TCC +  G + CCP   AVCC DK HCCP+ T+CN+ + TC+     +    K   L++    N  ++C D    C  G TCC    G + CCP   AVCC D   CCPQ T CNL A TCD         TK P+L +        N VIC   +  C DG TCCK P GD + CCP   A CC D  HCCPQ T CN+   TCD          +  AL +   P +V    C + S C    TCC   +  + CCP P AVCC DH HCCP  T+C+L  + CDK  L
Sbjct:    1 QAVCCSDGLHCCPSGTVCDLAHGMCQKGKISVPWLEKTPTFTPRTWRWRLARSLAVRPPQCPDGTSCGDDATCCPLASGQYGCCSLEDAVCCSDYLHCCPKNTMCDLKLGKCVHGKLSIPWVSKYPSKQAAS---DVQCDAFTSCSDQNTCCILPSGQWGCCPLPKAVCCDDKEHCCPEGTICNVTSQTCNHAALSLPWSTKTPALRMTGEPN-DVQC-DDLVGCPDGNTCCKTPGGDWACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVA----GEPNVVIC-DDQSSCPDGNTCCKTPGGD-WACCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQGTLSLPWSTKTPALRVAGEPNVV---ICDDQSSCPDGNTCCKMPSGDWGCCPLPKAVCCDDHQHCCPEGTTCNLPVERCDKGTL 426          

HSP 6 Score: 199.904 bits (507), Expect = 5.395e-56
Identity = 123/299 (41.14%), Postives = 148/299 (49.50%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK---LKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP------------DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPN 1112
            G + CCP   AVCC D +HCCPQ T CNL   TCD     +      K PA  +      V+C DQ  C DG TCC +  G + CCP   AVCC D  HCCPQ T CNL A TCD     +    K   L+V A     V C DQ  C D +TCC    G + CCP   AVCC D  HCCP+ T CN+ AG+CD    ++      K PA + L+   P            D +  C  G TCC L  G +GCCP   A CCSD + CCP    C+L+  +C    KKP  L  T+ P 
Sbjct:  466 GDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDQ--GTLSLPWSTKTPALRVAGEPNVVICDDQFSCPDGDTCCKMPSGDWGCCPLVKAVCCDDHEHCCPQGTTCNLPAQTCDKGALSLPWSTKTPALRV-AGEPNDVKCDDQVSCPDQTTCCKTGTGDWGCCPLVKAVCCDDHEHCCPEGTTCNVPAGSCDQG--QLSLPWSSKTPARTRLTALLPASAAARGGSVRCDSAYACPDGTTCCQLPQGQWGCCPLPLATCCSDFVHCCPSGYTCDLAQASC---IKKPHFL--TWAPK 754          
BLAST of Granulin b vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001039.1 (pep scaffold:Pmarinus_7.0:GL484091:11570:24665:-1 gene:ENSPMAG00000000936.1 transcript:ENSPMAT00000001039.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 179.104 bits (453), Expect = 1.623e-49
Identity = 141/423 (33.33%), Postives = 181/423 (42.79%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTK-IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE-IKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            +  G + CC    A CCSD  HCCP  T C + +    + L   + K   L  P    + V C     C    TCC    G + CC    A CCSD  HCCP  T C +      + L   + K   L  P    L V C     C    TCC    G + CC    A CCSD  HCCP  T C +      + L   + K       + +  + C  G   C+   TCC    G +GCC    A CCSD + CCP     +L     +S    P L  +     PV  N V C G +Y C   QTCC+   G  +GCC    ATCCSD IHCCP  T C +    C   +EAL  +  S  L  ++   +   C +  TCC S    + CC    A CCSD  HCCP+ T C +  + C ++
Sbjct:  160 SRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNV-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNVVHC-GGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQY-CRRWQTCCRSRRG-MWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSGVAGSSTLSHALPYDSRVYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRS 577          

HSP 2 Score: 177.948 bits (450), Expect = 4.072e-49
Identity = 144/433 (33.26%), Postives = 185/433 (42.73%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNL-NKGTC---DSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKIS-PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            G + CC    A CCSD  HCCP  T C +  +G C    +++  +  +  L  P    L V C     C    TCC    G + CC    A CCSD  HCCP  T C +    C    + +     L        +VV C     C    TCC    G + CC    A CCSD  HCCP  T C +      + L   + K       + +  + C  G   C+   TCC    G +GCC    A CCSD + CCP  T C L     +S    P L  +     PV  N V C G +Y C   QTCC+   G  +GCC    ATCCSD IHCCP  T C +  G C + A  +     E  +S P+    + C  G  C +  TCC S    + CC    A CCSD  HCCP+  S  L  +  +   L+ +
Sbjct:    7 GMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSVLDYLSREQQDGYNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNVVHC-GGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRC-LVGQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQY-CRRWQTCCRSRCG-MWGCCNGRKATCCSDGIHCCPSMTRCLV--GQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQCVNSAALIPW 432          

HSP 3 Score: 175.252 bits (443), Expect = 3.513e-48
Identity = 146/426 (34.27%), Postives = 183/426 (42.96%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKIS-PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            G + CC    A CCSD  HCCP  T C +    C    + +     L        +VV C     C    TCC    G + CC    A CCSD  HCCP  T C +      + L   + K   L  P    + V C     C    TCC    G + CC    A CCSD  HCCP  T C +      + L   + K   L  P   NL + C  G   C+   TCC    G +GCC    A CCSD + CCP  T C L     +S    P L  +     PV  N V C G +Y C   QTCC+   G  +GCC    ATCCSD IHCCP     ++ KG C + A  +     E  +S P+    + C  G  C +  TCC S    + CC    A CCSD  HCCP+ T C +  + C ++
Sbjct:   86 GMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSVLDYLSREQQDGYNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNV-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNL-VHC-GGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRC-LVGQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQY-CRRWQTCCRSRRG-MWGCCNGRRATCCSDGIHCCPSGASGDL-KGQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRS 504          

HSP 4 Score: 146.747 bits (369), Expect = 3.993e-38
Identity = 121/347 (34.87%), Postives = 150/347 (43.23%), Query Frame = 3
Query:  483 CCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLD-AGTC---DSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV--NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKIS-PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            CC    G + CC    A CCSD  HCCP  T C +   G C    + +  +  +  L  P    L V C     C    TCC    G + CC    A CCSD  HCCP  T C +    C    + +     L        ++    G   C+   TCC    G +GCC    A CCSD + CCP  T C L     +S    P L  +     PV  N V C G +Y C   QTCC+   G  +GCC    ATCCSD IHCCP  T C +  G C + A  +     E  +S P+    + C  G  C +  TCC S    + CC    A CCSD  HCCP+ T C
Sbjct:    1 CCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVPYRLCSRSSEALSVLDYLSREQQDGYNVVHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRC-LVGQCVNSAALIPWLKKEAALSGPVGDNVVHCGGGQY-CRRWQTCCRSRCG-MWGCCNGRRATCCSDGIHCCPSMTRCLV--GQCVNSAALIPWLKKEAALSGPVGDNLVHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRC 341          

HSP 5 Score: 142.124 bits (357), Expect = 1.648e-36
Identity = 115/352 (32.67%), Postives = 148/352 (42.05%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTK-IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTK-MKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK--LKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALE 1316
            G + CC    A CCSD  HCCP  T C + +    + L   + K   L  P    L V C     C    TCC    G + CC    A CCSD  HCCP  T C +      + L   + K   L  P    + V C     C    TCC    G + CC    A CCSD  HCCP     +L     +S   +  +  +  L  P   NL + C  G   C+   TCC    G +GCC    A CCSD + CCP  T C +    C   ++    L      + ++  +   ++  C   QTCC+   G  +GCC    ATCCSD IHCCP  T C +    C   +EAL 
Sbjct:  239 GMWGCCNGRRATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNL-VHCGGGQYCRRWQTCCRSRCGMWGCCNGRKATCCSDGIHCCPSMTRCLVGQCVNSAALIPWLKKEAALSGPVGDNV-VHCGGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSGASGDLKGQCVNSAALIPWLKKEAALSGPVGDNL-VHC-GGGQYCRRWQTCCRSRRGMWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLC---SRSSEALSGVAGSSTLSHALPYDSRVYCRRWQTCCRSRCG-MWGCCNGRRATCCSDGIHCCPSMTRCLVPYRLCSRSSEALS 582          
BLAST of Granulin b vs. Ensembl Nematostella
Match: EDO27824 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T870])

HSP 1 Score: 137.887 bits (346), Expect = 1.649e-37
Identity = 88/227 (38.77%), Postives = 110/227 (48.46%), Query Frame = 3
Query:  423 ASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD-SKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK----------LKIPAISNLSIE-CPDGSS----TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAG 1055
            AS    + C D S C D  TCC ++ GSY CCP  +AVCCSD +HCCP    C++ + TCD +K    +      V  + +  + C D S CN G TCC V    Y CCP  SAVCC+D +HCCP    CN  +G C      +    K           K P I + +I   P G       C+   TCC  S     CCP  NA CCSD L CCPQ  +C+   G
Sbjct:    1 ASGANYITCNDGSHCYDYETCCELSTGSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHCQRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGCACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFICDDQKG 227          

HSP 2 Score: 115.161 bits (287), Expect = 2.496e-29
Identity = 90/229 (39.30%), Postives = 113/229 (49.34%), Query Frame = 3
Query:  897 IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD-SKTKKPSLLIK-TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-------------EIKISPILVE-SIK-CPNGSL-----CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            I C DGS  C    TCC LS GSYGCCP  NAVCCSD   CCP    C++S+ TCD +K   P +    T Q   V  + C    + C+ G+TCC L     YGCCP  +A CC+D  HCCP    CN   G C      L              +  +P++++ +I+  P G       C    TCC S++   +CCP PNA CCSD  HCCP    C  + K C K 
Sbjct:    7 ITCNDGSH-CYDYETCCELSTGSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSH-CNTGETCC-LVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHCQRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGCACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFICD-DQKGCVKQ 231          

HSP 3 Score: 113.235 bits (282), Expect = 1.182e-28
Identity = 74/203 (36.45%), Postives = 93/203 (45.81%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV-VTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVC-------------PDQSQ-----CNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAG 824
            GSY CCP  +AVCCSD +HCCP    C+++  TCD       +      V  + +  + C D S CN G TCC V    Y CCP  SAVCC+D +HCCP    CN  +G C  +    V  M  K P+      V              P   +     C    TCC  +     CCP  +A CCSD  HCCPQ  +C+   G
Sbjct:   27 GSYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHC--QRGRHVLPMFQKHPSVHPRPAVAKTPVIIDHTIRFVPRGGRGAGCACEPYHTCCGSSSAQQNCCPLPNASCCSDGLHCCPQGFICDDQKG 227          

HSP 4 Score: 76.2554 bits (186), Expect = 8.976e-16
Identity = 58/195 (29.74%), Postives = 77/195 (39.49%), Query Frame = 3
Query:  984 SNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI-----KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            +N + C+D   C    T C LS G                                              SYGCCP   A CCSD  HCCP    C+I+  TCD   ++  +      +    V  IKC +GS C    TCC      Y CCP P+AVCC+D  HCCP+  +C+  +  C +   +  P+   HP
Sbjct:    4 ANYITCNDGSHCYDYETCCELSTG----------------------------------------------SYGCCPLPNAVCCSDGKHCCPCGYHCDISSSTCDMAKDSTPMVSYHATVQRAGVGEIKCKDGSHCNTGETCCLVGPTKYGCCPLPSAVCCADMQHCCPSGYTCNDKSGHCQRGRHV-LPMFQKHP 151          
BLAST of Granulin b vs. Ensembl Medaka
Match: grnb (granulin precursor [Source:NCBI gene;Acc:101166910])

HSP 1 Score: 283.108 bits (723), Expect = 6.554e-86
Identity = 179/466 (38.41%), Postives = 240/466 (51.50%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSI---------LSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA-------ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCD--SKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQ-----------TCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQA----EALEIKISPIL---VESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            DGS+ CCP+  AVCC D++HCCP+ T C+L    C S   +    ++ KVPA  +          SVVCP  +S C +  TCC +  G + CCPY  A CCSD  HCCP NT C+L+ G C S    V     ++  ++S   V+CPDQ S C DG+TCC +  G++ CCP  +AVCCSD  HCCP+ T C+L   TC S        + + +         +  L++ C + S  C  G+TCC  S G +GCCP   AVCC D L CCP  TVCNL A TCD  S +    LL  T           PG  Y+  +G+           TCC+  AG  + CCP   A CC D IHCCP  T+CN+   TCD  +        +   P L   +E  KC   ++C  + TCC +++  ++CCP P AVCCSD  HCCP    C+   ++C++      P     P
Sbjct:   69 DGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQ-KVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEARV---EPIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPC-NASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNT-----------PGFPYRSENGRCDESASCPGEATCCRTRAG-GWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGMEEEKCGKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWRQKLP 517          

HSP 2 Score: 273.863 bits (699), Expect = 1.736e-82
Identity = 164/398 (41.21%), Postives = 222/398 (55.78%), Query Frame = 3
Query:  417 VPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSI---------LSVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK---TKKPSLLIKTFQP---NPVNRVICP-GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH-QAEALEIKIS-----PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538
            +P + + +V+CPDQ S+C D +TCC +  GS+ CCP+  AVCC D+RHCCP+ T C+L    C S   +    ++ KVPA  +          SVVCP  +S C +  TCC +  G + CCPY  A CCSD  HCCP NT C+L+ G C S    V     ++  + S   + CPD  S C  G TCC L++G++GCCP  NAVCCSD + CCP+ T C+L+  TC S    T +  ++  +  P   +PV  +  P  A   C+DG TCC+   G  +GCCP   A CC D +HCCP  TVCN+   TCD     AL   +S     P   E+ +C   + C  + TCC +    ++CCP P AVCC DH HCCPN T C+L  ++CD    L  P+
Sbjct:   41 LPHTRVGAVICPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQ-KVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEARV---EPIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQ-WGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPL 433          

HSP 3 Score: 265.388 bits (677), Expect = 2.349e-79
Identity = 174/494 (35.22%), Postives = 234/494 (47.37%), Query Frame = 3
Query:  147 VYRFSREFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPAS-------SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSV--VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCD--SKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS--------KTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            V +     ++PI   +  P  V+     S+C DG++CC   +G++ CCP  +AVCCSD  HCCP+ T C+L   TC S        + + V  +         L+V C     C DGSTCC  + G + CCP   AVCC D  HCCP  TVCNL A TCD      +T +    P     S    C + + C   +TCC    G +ACCP   AVCC D  HCCP  T+CNL+A TCD  S L   +  +  +    + +  E     + C    TCC  S G + CCP   AVCCSD   CCP+   CN    TC+         + K P+L  ++ Q  PV       A+  C    TCC +     +GCCP   A CC D  HCCP+   C  ++ +C   +  +           P  V  +KC N S C    TCCP     + CCP   AVCC+DH HCCP + +C++ T +C+K      P+    P
Sbjct:  187 VCKSGEARVEPIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGMEEEKCGKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWRQKLPALQQRSGQTGPVENKC--DAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRGSHVVPWFTKVGALTEPSGVTDVKCDNKSSCASGTTCCPLQTGGWGCCPLVKAVCCADHEHCCPQSYTCNMQTGTCEKKAGQGLPLSRVVP 678          

HSP 4 Score: 264.618 bits (675), Expect = 4.511e-79
Identity = 172/449 (38.31%), Postives = 217/449 (48.33%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPAS-------SILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP-DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK----------TKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD----------HQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSAND-SYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            + T G + CCPY  A CCSD  HCCP NT C+L +G C S    V     ++  ++S   V+CPDQ S C DG+TCC +  G++ CCP  +AVCCSD  HCCP+ T C+L   TC S        + + V  +         L+V C     C DGSTCC  + G + CCP   AVCC D  HCCP  TVCNL A TCD      +T +    P     S     D S++C   ATCC    G + CCP   AVCC D + CCP  T+CNL A TCD            TK+P L     +       +CPG         TCCK  +G  + CCP   A CCSD  HCCP+   CN    TC+           +  AL+ +         KC   + C +  TCC       + CCP P AVCC D +HCCP   SC  +  SC + 
Sbjct:  151 LLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEARVE---PIRAVSASPEDVLCPDQRSMCPDGTTCCQLNNGTFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRLTAGMEEEKCGKDAVCPGRT-------TCCKNSSGQ-WACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSLPWRQKLPALQQRSGQTGPVENKCDAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRG 588          

HSP 5 Score: 233.417 bits (594), Expect = 1.540e-67
Identity = 156/447 (34.90%), Postives = 208/447 (46.53%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSV--VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP------DGSSTCKTGATCCLLSDG-SYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKT---FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAE-----ALEIKISPILVESIKCPN-GSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF 1532
            + G + CCP   AVCC D  HCCP  T CNL   TCD      +T +    P     S    C + + C   +TCC    G +ACCP   AVCC D  HCCP  T+CNL+A TCD        L  +  + +L    + +    C   + C   +TCC  + G +ACCP   AVCCSD  HCCP+   CN    TC+      +   + K+PA+   S +        D  ++C    TCC +     +GCCP   AVCC D   CCP+   C     +C   +       K     +P+ V  V C   K  C+ G TCC L  G  +GCCP   A CC+D  HCCPQ+  CN+  GTC+ +A      +  +   P   + + C   G   C ++ TCC  +  ++ CCP P AVCC D  HCCP   SC L    C     L +
Sbjct:  310 SRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYRSENGRCDESASCPGEATCCRTRAGGWACCPLPQAVCCDDHIHCCPNATICNLEAETCDDPSGLSPPLPWLTKRPRL---TAGMEEEKCGKDAVCPGRTTCCKNSSGQWACCPLPQAVCCSDLDHCCPKGYKCNAFDRTCERPGGPSL-PWRQKLPALQQRSGQTGPVENKCDAQTSCPKDTTCCFMEQTLKWGCCPLPQAVCCGDGNHCCPRGHSCQPHRSSCSRGSHVVPWFTKVGALTEPSGVTDVKC-DNKSSCASGTTCCPLQTG-GWGCCPLVKAVCCADHEHCCPQSYTCNMQTGTCEKKAGQGLPLSRVVPAQPQDTQDVPCDGTGEFKCPKQNTCCRISATAWGCCPSPGAVCCMDSKHCCPAGYSCDLKAGGCTLGPRLSW 750          

HSP 6 Score: 223.787 bits (569), Expect = 5.474e-64
Identity = 130/330 (39.39%), Postives = 182/330 (55.15%), Query Frame = 3
Query:  645 VPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA---------ISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC----DHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKF-PIINFHP*FNYY 1568
            +P + + +V+CPDQ S+C D +TCC +  GS+ CCP+  AVCC D+RHCCP+ T C+L    C S   +    ++ K+PA          +  S+ CP G S+C    TCCLL+ G +GCCP+  A CCSD L CCP NT C+L  G C S   +    I+    +P + V+CP  +  C DG TCC+L  G ++GCCP   A CCSD +HCCP+ T C++   TC       AEA+ + +S       P+   ++ C     C    TCC ++   + CCP P AVCC DH HCCP+ T C+L   +CD        P+++  P F Y 
Sbjct:   41 LPHTRVGAVICPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQ-KVPAQRVGTLPVFAAAASVVCPGGKSSCPNSFTCCLLTSGDFGCCPYPQATCCSDHLHCCPGNTTCDLERGVCKSGEAR-VEPIRAVSASPED-VLCPDQRSMCPDGTTCCQLNNG-TFGCCPLPNAVCCSDHMHCCPEGTTCDLAHSTCVSAAGGTAEAVMVPVSGTPPKTHPVRGLAVPCNASVACADGSTCCRASRGQWGCCPLPEAVCCEDHLHCCPHGTVCNLVASTCDDPSGSALTPLLSNTPGFPYR 366          

HSP 7 Score: 59.3066 bits (142), Expect = 8.798e-9
Identity = 34/102 (33.33%), Postives = 46/102 (45.10%), Query Frame = 3
Query: 1251 CPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            CP   VC        +        +    V ++ CP+  S C  + TCC   + S+ CCP+P AVCC D  HCCP  T+C L    C    L  FP++   P
Sbjct:   17 CPDGAVCADGHKCFLNSHGGFTCPLPHTRVGAVICPDQESECPDETTCCQLPDGSWGCCPFPKAVCCEDQRHCCPEGTTCDLVHSKCASPSLQAFPMLQKVP 118          
BLAST of Granulin b vs. Ensembl Medaka
Match: grna (granulins [Source:NCBI gene;Acc:101162601])

HSP 1 Score: 284.263 bits (726), Expect = 1.814e-84
Identity = 177/443 (39.95%), Postives = 235/443 (53.05%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ SN+S++  D    GS++C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +        K+S + +E + C   + C  + TCC + + ++ CCP P AVCC DH HCCP  T+C L+T SC K
Sbjct:  311 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGST-SCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLK 744          

HSP 2 Score: 258.84 bits (660), Expect = 3.171e-75
Identity = 171/498 (34.34%), Postives = 237/498 (47.59%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC----DSVL--------------------KEV------------VTKIKLKVPASSILS------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            +G ++CCP   AVCC DK HCCP+ T C++ +  C    D  L                    KEV              ++    P  + L             + C + + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ SN+S++      DGS++C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +           + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:  189 EGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 680          

HSP 3 Score: 250.366 bits (638), Expect = 3.459e-72
Identity = 174/491 (35.44%), Postives = 227/491 (46.23%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLS-------AGTCDSKTKKP---------SLLIKTFQP------NPVNR----------------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIK-------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*F 1559
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ S +S++  D    GS++C    TCC   DG++GCCP   AVCC D   CCP  T C+LS       +G      K P         S L+KT Q        P +R                +I   +  QC    TCC +     +GCCP   A CC+D  HCCP +  C     +C      +         +SI+       C     C +  +CC      + CCP PNAVCC D  HCCP   +C L +KSC K + L+   +   P F
Sbjct:  469 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTCDLASKSCHKLLTLQLETVPLTPVF 953          

HSP 4 Score: 224.942 bits (572), Expect = 3.045e-63
Identity = 157/501 (31.34%), Postives = 230/501 (45.91%), Query Frame = 3
Query:  279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV------LKEVVTKIKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA--------------ISNLSIE------------------CPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            Y CCP+  A CC D  HCCP++  C++   +C +       ++ V   +++   +  ++          +CPDQS+C      C  A   Y CCP +  V C D +HCCP+   C+LD+ +C              V   SI +V+C D  S+C D +TCC    G +ACCP   AVCC DK HCCP+ T C+++   C S   + +  M  K PA              +S +++E                    +GSS                +C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +           + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:   40 YDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC--------------VKKESIKTVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKAL-PMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 522          

HSP 5 Score: 217.624 bits (553), Expect = 9.820e-61
Identity = 165/507 (32.54%), Postives = 230/507 (45.36%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV-VTKMKLKIPAISNLS----------------------------------------IECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICP-------GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIK---ISPILVESIKCPNGSL------------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FN 1562
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G++ CCP   AVCC D  HCCP  T C+L   +C   LK   +  M  K+PA +  S                                        I C D  + C    TCC +     +GCCP   AVCC+D   CCP +  C       D+   K  ++I  +   P    I          A +QC +  +CC+L  G+ +GCCP   A CC DK HCCP+   C++   +C H+   L+++   ++P+ +   +  +G +            C    TCC +++ ++ CC  P AVCC D  HCCP+   C+    SC KN  L +  +N+H  F 
Sbjct:  548 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC---LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISC-DSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEE----DTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGE-WGCCPLPNAVCCGDKEHCCPEGYTCDLASKSC-HKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHW--LNWHTFFT 1037          

HSP 6 Score: 191.815 bits (486), Expect = 7.672e-52
Identity = 130/451 (28.82%), Postives = 200/451 (44.35%), Query Frame = 3
Query:  417 VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------------QPNPVNRVICPGAKYQ------------------------------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            V  + + + +CP+  +C  G TCC      Y CCP+  A CC D  HCCP++ +C++   +C +       ++ V   +++   +  ++          +CPDQS+C      C  A   Y CCP +  V C D +HCCP+   C+LD+ +C       V K  +K       ++ C DG S C    TCC   +G + CCP   AVCC DK+ CCP+ T C++    C S + K   +   F            +   V+ V   G + +                                    C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +        K+S + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:   10 VSLALVAADMCPNGGKCEKGQTCCQSPSKDYDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC-------VKKESIK-------TVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 443          

HSP 7 Score: 129.028 bits (323), Expect = 6.619e-31
Identity = 103/351 (29.34%), Postives = 142/351 (40.46%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----------------------------------------VVCPDQSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI 1130
            T DG++ CCP   AVCC D +HCCP  T C+L+  +C  +    +  +  K+PAS+  S                                        + C   +QC   +TCC +     + CCP   AVCC+D  HCCP +  C  +  +C     EVV     K+PA+  +      V C    QC +  +CC +  G + CCP  +AVCC DK HCCP+         TCD   K     + L++  +    +  PD  S                +C    TCC  S  ++GCC    AVCC D   CCP    C    G+C   T    L   TF  N    +I
Sbjct:  706 TKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC--LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKG--EVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGY-------TCDLASKSCHKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHWLNWHTFFTNKRKAII 1044          
BLAST of Granulin b vs. Ensembl Medaka
Match: grna (granulins [Source:NCBI gene;Acc:101162601])

HSP 1 Score: 281.952 bits (720), Expect = 2.406e-83
Identity = 176/443 (39.73%), Postives = 234/443 (52.82%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ S +S++  D    GS++C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +        K+S + +E + C   + C  + TCC + + ++ CCP P AVCC DH HCCP  T+C L+T SC K
Sbjct:  390 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLK 823          

HSP 2 Score: 278.1 bits (710), Expect = 7.361e-82
Identity = 173/457 (37.86%), Postives = 235/457 (51.42%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ SN+S++      DGS++C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +           + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:  311 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 759          

HSP 3 Score: 260.766 bits (665), Expect = 1.119e-75
Identity = 173/499 (34.67%), Postives = 240/499 (48.10%), Query Frame = 3
Query:  270 DGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC----DSVL--------------------KEV------------VTKIKLKVPASSILS------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECP----DGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            +G ++CCP   AVCC DK HCCP+ T C++ +  C    D  L                    KEV              ++    P  + L             + C + + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ SN+S++      DGS++C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +        K+S + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:  189 EGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 680          

HSP 4 Score: 250.751 bits (639), Expect = 3.302e-72
Identity = 174/491 (35.44%), Postives = 227/491 (46.23%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPD----GSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLS-------AGTCDSKTKKP---------SLLIKTFQP------NPVNR----------------VICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIK-------CPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*F 1559
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  K+P+ S +S++  D    GS++C    TCC   DG++GCCP   AVCC D   CCP  T C+LS       +G      K P         S L+KT Q        P +R                +I   +  QC    TCC +     +GCCP   A CC+D  HCCP +  C     +C      +         +SI+       C     C +  +CC      + CCP PNAVCC D  HCCP   +C L +KSC K + L+   +   P F
Sbjct:  548 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSCLKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGYTCDLASKSCHKLLTLQLETVPLTPVF 1032          

HSP 5 Score: 225.328 bits (573), Expect = 3.471e-63
Identity = 157/501 (31.34%), Postives = 230/501 (45.91%), Query Frame = 3
Query:  279 YSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSV------LKEVVTKIKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQ-SQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPA--------------ISNLSIE------------------CPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPV----NRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKIS-------PILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            Y CCP+  A CC D  HCCP++  C++   +C +       ++ V   +++   +  ++          +CPDQS+C      C  A   Y CCP +  V C D +HCCP+   C+LD+ +C              V   SI +V+C D  S+C D +TCC    G +ACCP   AVCC DK HCCP+ T C+++   C S   + +  M  K PA              +S +++E                    +GSS                +C    TCC   +G +GCCPF  AVCC D + CCP+   CNL+A TC+       +L K    + V      V C G+   C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +           + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:   40 YDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC--------------VKKESIKTVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKAL-PMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVSVKMEDVPCDGS-TSCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 522          

HSP 6 Score: 218.009 bits (554), Expect = 9.348e-61
Identity = 165/507 (32.54%), Postives = 230/507 (45.36%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-----QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEV-VTKMKLKIPAISNLS----------------------------------------IECPDGSSTCKTGATCCLLSD-GSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICP-------GAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIK---ISPILVESIKCPNGSL------------CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*FN 1562
            T +G + CCP+  AVCC D  HCCP+   CNL   TC+     V   +  KVP+ S +SV   D      + C D +TCC    G + CCP+  AVCC D  HCCP+   CNL A TC+     V   M  KVP+ S +SV   D      + C D +TCC    G++ CCP   AVCC D  HCCP  T C+L   +C   LK   +  M  K+PA +  S                                        I C D  + C    TCC +     +GCCP   AVCC+D   CCP +  C       D+   K  ++I  +   P    I          A +QC +  +CC+L  G+ +GCCP   A CC DK HCCP+   C++   +C H+   L+++   ++P+ +   +  +G +            C    TCC +++ ++ CC  P AVCC D  HCCP+   C+    SC KN  L +  +N+H  F 
Sbjct:  627 TQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSNVSVKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSV--PMLEKVPSFSKVSVKMEDVPCDGSTSCPDQTTCCKTKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC---LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISC-DSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEE----DTSCVKGEVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGE-WGCCPLPNAVCCGDKEHCCPEGYTCDLASKSC-HKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHW--LNWHTFFT 1116          

HSP 7 Score: 192.2 bits (487), Expect = 7.647e-52
Identity = 130/451 (28.82%), Postives = 200/451 (44.35%), Query Frame = 3
Query:  417 VPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK------LKEVVTKMKLKVPASSILSV--------VCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTF------------QPNPVNRVICPGAKYQ------------------------------------CSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEI--------KISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN-----ILLKFPIIN 1544
            V  + + + +CP+  +C  G TCC      Y CCP+  A CC D  HCCP++ +C++   +C +       ++ V   +++   +  ++          +CPDQS+C      C  A   Y CCP +  V C D +HCCP+   C+LD+ +C       V K  +K       ++ C DG S C    TCC   +G + CCP   AVCC DK+ CCP+ T C++    C S + K   +   F            +   V+ V   G + +                                    C D  TCCK   G  +GCCP+  A CC D IHCCP+   CN+   TC+    ++ +        K+S + +E + C   + C  + TCC +    + CCP+P AVCC D  HCCP   +C+L  ++C+ +     +L K P  +
Sbjct:   10 VSLALVAADMCPNGGKCEKGQTCCQSPSKDYDCCPFDEAECCGDHIHCCPKDMLCDMTTSSCGNATLSMRWVERVSANLQMATKSFRMIRSYMGEDEDNICPDQSRCP-AEFSCLKALTRYGCCPLAQGVSCPDGKHCCPEGHQCSLDSRSC-------VKKESIK-------TVLCKDGVSECPDETTCCENQEGKWACCPMPKAVCCDDKIHCCPEETTCDVEQMKCLSSSDKALPMWAKFPARTRADWENQKEGKEVSAVAVEGNETKNFPEVTTANPVPAFLEGSSVAGEASAKDIPCNETASCPDQTTCCKTQEG-GWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFSKVS-VKMEDVPCDGSTSCPDQTTCCKTQEGGWGCCPFPEAVCCEDFIHCCPKGKTCNLAAQTCEGDGGSVPMLEKVPSFS 443          

HSP 8 Score: 129.028 bits (323), Expect = 6.393e-31
Identity = 103/351 (29.34%), Postives = 142/351 (40.46%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILS----------------------------------------VVCPDQSQCNDGSTCCAVAG-GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILS-----VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSS----------------TCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI 1130
            T DG++ CCP   AVCC D +HCCP  T C+L+  +C  +    +  +  K+PAS+  S                                        + C   +QC   +TCC +     + CCP   AVCC+D  HCCP +  C  +  +C     EVV     K+PA+  +      V C    QC +  +CC +  G + CCP  +AVCC DK HCCP+         TCD   K     + L++  +    +  PD  S                +C    TCC  S  ++GCC    AVCC D   CCP    C    G+C   T    L   TF  N    +I
Sbjct:  785 TKDGAWGCCPLPEAVCCDDHEHCCPTGTTCDLSTLSC--LKASGLVPMSKKLPASTRTSSATSQLMKTGQETEEGENKPDDRDGQEDFDEEDKTDEEGIISCDSHTQCPQHTTCCFMKQVQKWGCCPLPKAVCCADGEHCCPADYKCKEEDTSCVKG--EVVIPWYTKIPATDSIQADSSFVQCSAVHQCPEHMSCCRLFTGEWGCCPLPNAVCCGDKEHCCPEGY-------TCDLASKSCHKLLTLQLETVPLTPVFLPDDQSQHGPVKPILNRCDDVYSCNVDETCCRTSHTTWGCCLSPKAVCCRDMKHCCPDGYRCT-KGGSCIKNTGLHWLNWHTFFTNKRKAII 1123          
BLAST of Granulin b vs. Ensembl Medaka
Match: ENSORLT00000029765.1 (granulins [Source:NCBI gene;Acc:101168633])

HSP 1 Score: 102.064 bits (253), Expect = 9.957e-24
Identity = 82/273 (30.04%), Postives = 112/273 (41.03%), Query Frame = 3
Query:  405 IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVV-----TKMKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------------------DSKLKEVVTKMKLKIPAISNLS--------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC 1061
            + L V   +  S+ CPD   C D STCC + G  ++CCP   AVCCSDK HCCP    CNL    C+   +  V     TK   + P +  LS                   V C     C D +TCC    G++ CCPY    CC D  HCCP    C+L    C                       S  +E   +++  + A++  S        I C D    C  G +CC  ++G + CCP+    CC+D   CC     C+ ++ TC
Sbjct:   10 VGLSVCGFAFCSIECPDGKLCPDLSTCC-LTGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRC-DSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 280          

HSP 2 Score: 100.523 bits (249), Expect = 3.053e-23
Identity = 81/277 (29.24%), Postives = 111/277 (40.07%), Query Frame = 3
Query:  861 MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS----LLIKTFQPNPVNRVICPG---------------------AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------------------------DHQAEALEIKISPILVES--------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDK 1514
            + L +   +  SIECPDG   C   +TCCL   G + CCP   AVCCSDK  CCP    CNL+   C+ KT +P     +L K     P    +                        + Y C D  TCC+ P G ++ CCPY    CC D  HCCP    C++    C                          +  +  LE  ++ +   S        I+C +   C    +CC  A   ++CCPYP   CC+D  HCC    +C   + +C K
Sbjct:   10 VGLSVCGFAFCSIECPDGK-LCPDLSTCCLTGHG-FSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCE-KTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKG-AWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATCRK 282          

HSP 3 Score: 96.2857 bits (238), Expect = 8.857e-22
Identity = 74/242 (30.58%), Postives = 97/242 (40.08%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-----VLKEVVTKIKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------DSKLKEVVTKMKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 830
            T   +SCCP   AVCCSDK HCCP    CNL    C+      V   ++TK   + P +  LS                   V C     C D +TCC    G++ CCPY    CC D  HCCP    C+L    C                               +L++ +T +     A S   V+ C  +  C  G++CC  A G + CCPY    CC+D RHCC     C+  + TC
Sbjct:   39 TGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 280          
BLAST of Granulin b vs. Ensembl Medaka
Match: ENSORLT00000005071.2 (granulins [Source:NCBI gene;Acc:101168633])

HSP 1 Score: 102.064 bits (253), Expect = 1.032e-23
Identity = 82/273 (30.04%), Postives = 112/273 (41.03%), Query Frame = 3
Query:  405 IKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVV-----TKMKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----------------------DSKLKEVVTKMKLKIPAISNLS--------IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC 1061
            + L V   +  S+ CPD   C D STCC + G  ++CCP   AVCCSDK HCCP    CNL    C+   +  V     TK   + P +  LS                   V C     C D +TCC    G++ CCPY    CC D  HCCP    C+L    C                       S  +E   +++  + A++  S        I C D    C  G +CC  ++G + CCP+    CC+D   CC     C+ ++ TC
Sbjct:   12 VGLSVCGFAFCSIECPDGKLCPDLSTCC-LTGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRC-DSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 282          

HSP 2 Score: 102.064 bits (253), Expect = 1.062e-23
Identity = 83/285 (29.12%), Postives = 115/285 (40.35%), Query Frame = 3
Query:  861 MKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPS----LLIKTFQPNPVNRVICPG---------------------AKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC--------------------------DHQAEALEIKISPILVES--------IKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPI 1538
            + L +   +  SIECPDG   C   +TCCL   G + CCP   AVCCSDK  CCP    CNL+   C+ KT +P     +L K     P    +                        + Y C D  TCC+ P G ++ CCPY    CC D  HCCP    C++    C                          +  +  LE  ++ +   S        I+C +   C    +CC  A   ++CCPYP   CC+D  HCC    +C   + +C K   L +P+
Sbjct:   12 VGLSVCGFAFCSIECPDGK-LCPDLSTCCLTGHG-FSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCE-KTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKG-AWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATCRK---LSYPV 289          

HSP 3 Score: 96.2857 bits (238), Expect = 8.942e-22
Identity = 74/242 (30.58%), Postives = 97/242 (40.08%), Query Frame = 3
Query:  267 TDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS-----VLKEVVTKIKLKVPASSILS-------------------VVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------------------------DSKLKEVVTKMKLKVPASSILSVV-CPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC 830
            T   +SCCP   AVCCSDK HCCP    CNL    C+      V   ++TK   + P +  LS                   V C     C D +TCC    G++ CCPY    CC D  HCCP    C+L    C                               +L++ +T +     A S   V+ C  +  C  G++CC  A G + CCPY    CC+D RHCC     C+  + TC
Sbjct:   41 TGHGFSCCPLPEAVCCSDKAHCCPSGYRCNLATMMCEKTDQPWVSLPMLTKEAAEEPPALDLSTNLVEELKNDNGLAQKSTGVQCDSFYMCPDRTTCCRHPKGAWFCCPYYPGRCCLDGFHCCPYGYDCDLTYTHCIRDGFKYPFYYKQALTSVPAALISHPEENSIQLEKSLTALTEASDAPSEHGVIRCDSKFFCPAGTSCCKGAEGQWTCCPYPLGKCCADGRHCCQYGYTCDATSATC 282          
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000029882.1 (SMESG000029882.1)

HSP 1 Score: 822.002 bits (2122), Expect = 0.000e+0
Identity = 420/427 (98.36%), Postives = 424/427 (99.30%), Query Frame = 3
Query:  273 GSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 1553
            GSY+CCPYSSAVCCSDK+HCCPQNT CNL+ GTCDS LKEVVTK+KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP
Sbjct:  288 GSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP 714          

HSP 2 Score: 665.996 bits (1717), Expect = 0.000e+0
Identity = 373/495 (75.35%), Postives = 412/495 (83.23%), Query Frame = 3
Query:   96 MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQP-NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA----LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-------LLKFPIIN 1544
            MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNCPDDSVCDDGSSCCVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQC+DGS+CC +A G+YACCPYSSAVCCSDK+HCCPQNTVCNL AGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCC VAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLK+PA S LS+ CPD  S C  G+TCC ++ GSY CCP+S+AVCCSDK  CCPQNTVCNL AGTCDSK K+    +K   P + +  V+CP  + QC+DG TCC + AG SY CCPYS+A CCSDK HCCPQNTVCN++ GTCD + +     +++K+    + S+ CP+ S C    TCC  A  SY+CCPY +AVCCSD  HCCP NT C+L+  +CD  +        LK P I+
Sbjct:    1 MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNCPDDSVCDDGSSCCVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPDQSQCDDGSSCCVMADGNYACCPYSSAVCCSDKQHCCPQNTVCNLSAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCEVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCEVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS 492          

HSP 3 Score: 188.734 bits (478), Expect = 9.475e-52
Identity = 108/211 (51.18%), Postives = 139/211 (65.88%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPASSILSVVCPD-QSQCNDGSTCCAV-AGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAIS 887
            + +DGSY CCP+S+AVCCSDK  CCPQNT CNL+ GTCDS  K+    IK   P + +  V+CP  + QC+DG TCC + AG SY CCPYS+A CCSDK HCCPQNTVCN++ GTCD + +     +++K+    + S+ CP+ S C    TCC  A  SY+CCPY +AVCCSD  HCCP NT C+L+  +CD  +        LK P I+
Sbjct:  513 LLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQP-NPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA----LEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-------LLKFPIIN 711          
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1)

HSP 1 Score: 224.557 bits (571), Expect = 3.013e-65
Identity = 157/496 (31.65%), Postives = 244/496 (49.19%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLK-VPASSILSV--------------VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS---------KTKKPSLLIKTF--QPNPVNRV-ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-----DHQAEALEIKISPILVESIKCP-NGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC---DKNILLKFPI 1538
            VT  GSY CC +++AVCC DK HCCP+ + C+  +  C      +  +++++  +K++  P ++IL                +CP+ +++C +  TCC     SY CC Y++AVCC DK HCCP  T        CN +     S ++     M++ V   + + ++    CP+ +++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++ +++  +K++    +N+          + CP+  + CK   TCC+    +Y CCP  NAVCCSDK  CCP+ T C++    C S               L+  +F  + N    + +  G K + S     C +  G S G C +SA TCCSD   CCPQ+T C+     C     D   E  +   +   + ++ CP N + C    TCC  ++ SY CC   NAVCC+D   CCP+N  C + T SC   + N    FP+
Sbjct:  120 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRS-GRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPL 614          

HSP 2 Score: 217.624 bits (553), Expect = 9.481e-63
Identity = 152/495 (30.71%), Postives = 235/495 (47.47%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIK-----LKVPASS------ILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-VPASSILSV--------------VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKK--------PSLLIKT--------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV-ESIKCPNGS------LCGQKGTC------CPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            T   SY CC Y++AVCC DK HCCP  T C+     C+  ++   + I+     +++P         I    CP+ +++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++++++  +K++  P ++IL                +CP+ +++C +  TCC     SY CC Y++AVCC DK HCCP  T C+     C+  ++   + ++     +++P I    ++      CP+  + C+   TCC+   GSY CC F+NAVCC DK  CCP+ + C+     C    K         P+L ++          + N  + V+CP  K +C D +TCC +   ++Y CCP+  A CCSDK  CCP+ T C+I    C    H    +  +++  L+ +S K           L G K         CP  N     C +    CCSD   CCP +T C      C  N
Sbjct:   33 TKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCC-ITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLN 526          

HSP 3 Score: 204.527 bits (519), Expect = 7.618e-58
Identity = 141/468 (30.13%), Postives = 214/468 (45.73%), Query Frame = 3
Query:  402 KIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-------IPAISNLSIE--------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---------------------DHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCD------KNILLKFPIINFHP*FNYYLFVF 1580
            K+    P    +  +CP+ +++C +  TCC     SY CC Y++AVCC DK HCCP  T        CN +     S ++     M++ V   + + ++    CP ++++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++++++  +K++       + A  N   E        CP+  + C    TCC     SY CC ++NAVCC DK  CCP  T C+     C+   +     I+T  P P+   +             CP  + +C D QTCC    G SY CC ++ A CC DK HCCP+ + C+  +  C                     + +   LE K++    + + CPN  + C    TCC + +++Y CCP+ NAVCCSD   CCP  T+C +  K C         I  +      H  F Y    F
Sbjct:    2 KLNKSAPNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDENKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNE--KDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFF 465          
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1)

HSP 1 Score: 213.001 bits (541), Expect = 8.356e-61
Identity = 158/527 (29.98%), Postives = 245/527 (46.49%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS---------KTKKPSLLIKTF--QPNPVNRV-ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-----DHQAEALEIKISPILVESIKCP-NGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC---DKNILLKFPI 1538
            VT  GSY CC +++AVCC DK HCCP+ + C+  +  C      +  +++++  +K++  P ++IL         V+CP+                                      +++C +  TCC     SY CC Y++AVCC DK HCCP  T        CN +     S ++     M++ V   + + ++    CP ++++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++ +++  +K++    +N+          + CP+  + CK   TCC+    +Y CCP  NAVCCSDK  CCP+ T C++    C S               L+  +F  + N    + +  G K + S     C +  G S G C +SA TCCSD   CCPQ+T C+     C     D   E  +   +   + ++ CP N + C    TCC  ++ SY CC   NAVCC+D   CCP+N  C + T SC   + N    FP+
Sbjct:  120 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRS-GRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPL 645          

HSP 2 Score: 206.453 bits (524), Expect = 2.153e-58
Identity = 153/526 (29.09%), Postives = 236/526 (44.87%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIK-----LKVPASS------ILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKK--------PSLLIKT--------FQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV-ESIKCPNGS------LCGQKGTC------CPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            T   SY CC Y++AVCC DK HCCP  T C+     C+  ++   + I+     +++P         I    CP+ +++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++++++  +K++  P ++IL         V+CP+                                      +++C +  TCC     SY CC Y++AVCC DK HCCP  T C+     C+  ++   + ++     +++P I    ++      CP+  + C+   TCC+   GSY CC F+NAVCC DK  CCP+ + C+     C    K         P+L ++          + N  + V+CP  K +C D +TCC +   ++Y CCP+  A CCSDK  CCP+ T C+I    C    H    +  +++  L+ +S K           L G K         CP  N     C +    CCSD   CCP +T C      C  N
Sbjct:   33 TKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCC-ITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLN 557          

HSP 3 Score: 194.897 bits (494), Expect = 3.853e-54
Identity = 135/469 (28.78%), Postives = 211/469 (44.99%), Query Frame = 3
Query:  402 KIKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCP-------------------------------------FSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---------------------DHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508
            K+    P    +  +CP+ +++C +  TCC     SY CC Y++AVCC DK HCCP  T        CN +     S ++     M++ V   + + ++    CP ++++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++++++  +K++    +N+          + CP+  + CK   TCC+    +Y CCP                                     ++NAVCC DK  CCP  T C+     C+   +     I+T  P P+   +             CP  + +C D QTCC    G SY CC ++ A CC DK HCCP+ + C+  +  C                     + +   LE K++    + + CPN  + C    TCC + +++Y CCP+ NAVCCSD   CCP  T+C +  K C
Sbjct:    2 KLNKSAPNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNE--KDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKC 466          

HSP 4 Score: 167.933 bits (424), Expect = 1.248e-44
Identity = 108/312 (34.62%), Postives = 160/312 (51.28%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA--------SSILS--------VVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK---LKEVVTKM---------KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTF 1103
            VT  GSY CC +++AVCC DK HCCP+ + C+  +  C    K  V   KL +PA        ++IL         V+CP+ +++C D  TCC     +Y CCP+ +AVCCSDK  CCP+ T C++    C S    + E+  +M         K +     I+S++   + + +     C +  G    C +S+  CCSD R CCPQ+T C+     C     +  T+     P  + LS + CPD  + C +  TCC +SD SYGCC   NAVCC+D++SCCP N  C++   +C ++ + K      TF
Sbjct:  337 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKL-IPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPLTF 647          

HSP 5 Score: 119.783 bits (299), Expect = 2.895e-28
Identity = 92/298 (30.87%), Postives = 126/298 (42.28%), Query Frame = 3
Query:  858 KMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAE----------ALEIKISP---ILV------ESIKCPNG--------------------------------------SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPI 1538
            K+    P    +   CP+  + C    TCC     SY CC ++NAVCC DK  CCP  T C+     C+   +     I+T  P P+   +             CP  + +C D QTCC    G SY CC ++ A CC DK HCCP+ + C+  +  C   A+          AL+++  P   IL       + + CPN                                       + C ++ TCC + ++SY CC Y NAVCC D  HCCPN TSC    K C++NI   K PI
Sbjct:    2 KLNKSAPNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPI 297          
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018760.1 (SMESG000018760.1)

HSP 1 Score: 213.386 bits (542), Expect = 8.669e-61
Identity = 158/527 (29.98%), Postives = 245/527 (46.49%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTC------DSVLKEVVTKIKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDS---------KTKKPSLLIKTF--QPNPVNRV-ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC-----DHQAEALEIKISPILVESIKCP-NGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC---DKNILLKFPI 1538
            VT  GSY CC +++AVCC DK HCCP+ + C+  +  C      +  +++++  +K++  P ++IL         V+CP+                                      +++C +  TCC     SY CC Y++AVCC DK HCCP  T        CN +     S ++     M++ V   + + ++    CP ++++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++ +++  +K++    +N+          + CP+  + CK   TCC+    +Y CCP  NAVCCSDK  CCP+ T C++    C S               L+  +F  + N    + +  G K + S     C +  G S G C +SA TCCSD   CCPQ+T C+     C     D   E  +   +   + ++ CP N + C    TCC  ++ SY CC   NAVCC+D   CCP+N  C + T SC   + N    FP+
Sbjct:  149 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRS-GRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPL 674          

HSP 2 Score: 206.453 bits (524), Expect = 2.841e-58
Identity = 153/526 (29.09%), Postives = 235/526 (44.68%), Query Frame = 3
Query:  264 TTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIK-----LKVPASS------ILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLK-VPASSIL--------SVVCPD--------------------------------------QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC----DSKTKKPSLL------------IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD---HQAEALEIKISPILV-ESIKCPNGS------LCGQKGTC------CPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKN 1517
            T   SY CC Y++AVCC DK HCCP  T C+     C+  ++   + I+     +++P         I    CP+ +++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++++++  +K++  P ++IL         V+CP+                                      +++C +  TCC     SY CC Y++AVCC DK HCCP  T C+     C+  ++   + ++     +++P I    ++      CP+  + C+   TCC+   GSY CC F+NAVCC DK  CCP+ + C+     C     S  +   L+            I   + N  + V+CP  K +C D +TCC +   ++Y CCP+  A CCSDK  CCP+ T C+I    C    H    +  +++  L+ +S K           L G K         CP  N     C +    CCSD   CCP +T C      C  N
Sbjct:   62 TKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCC-ITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLN 586          

HSP 3 Score: 191.43 bits (485), Expect = 8.662e-53
Identity = 133/455 (29.23%), Postives = 207/455 (45.49%), Query Frame = 3
Query:  444 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNT-------VCNLDAGTCDSKLKEVVTKMKLKVPASSILSVV----CP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC------DSKLKEVVTKMKLKIPAISNL---------SIECPDGSSTCKTGATCCLLSDGSYGCCP-------------------------------------FSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVI-------------CPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTC---------------------DHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508
            +CP+ +++C +  TCC     SY CC Y++AVCC DK HCCP  T        CN +     S ++     M++ V   + + ++    CP ++++C D  TCC    GSY CC +++AVCC DK HCCP+ + C+     C      + ++++++  +K++    +N+          + CP+  + CK   TCC+    +Y CCP                                     ++NAVCC DK  CCP  T C+     C+   +     I+T  P P+   +             CP  + +C D QTCC    G SY CC ++ A CC DK HCCP+ + C+  +  C                     + +   LE K++    + + CPN  + C    TCC + +++Y CCP+ NAVCCSD   CCP  T+C +  K C
Sbjct:   45 ICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCCITKHNNYYCCPHKNNKETVGNICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQT-TPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHG-SYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKLIPALKVENELKTNILEAKVNE--KDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKC 495          

HSP 4 Score: 167.933 bits (424), Expect = 1.618e-44
Identity = 108/312 (34.62%), Postives = 160/312 (51.28%), Query Frame = 3
Query:  261 VTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEVVTKIKLKVPA--------SSILS--------VVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSK---LKEVVTKM---------KLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKIPAISNLS-IECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKTKKPSLLIKTF 1103
            VT  GSY CC +++AVCC DK HCCP+ + C+  +  C    K  V   KL +PA        ++IL         V+CP+ +++C D  TCC     +Y CCP+ +AVCCSDK  CCP+ T C++    C S    + E+  +M         K +     I+S++   + + +     C +  G    C +S+  CCSD R CCPQ+T C+     C     +  T+     P  + LS + CPD  + C +  TCC +SD SYGCC   NAVCC+D++SCCP N  C++   +C ++ + K      TF
Sbjct:  366 VTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMGKL-IPALKVENELKTNILEAKVNEKDEVMCPNNKTKCKDTKTCCITKHNNYYCCPHKNAVCCSDKYQCCPEATTCDIKNKKCTSSPHSIHEIAHEMAQELIHDSFKYETNFFKIISLLLGFKQKASKSDFYCPITNGRSGRCKFSAGTCCSDLRTCCPQHTKCDEKNNKCTLNSTDFDTEKSKHSPNTNRLSTVVCPDNETECFSWETCCAVSDKSYGCCELENAVCCADRVSCCPHNQKCDIKTNSCVETNSNKRRHFPLTF 676          

HSP 5 Score: 150.599 bits (379), Expect = 1.676e-38
Identity = 103/319 (32.29%), Postives = 154/319 (48.28%), Query Frame = 3
Query:  672 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVTKMK-----LKIPAISNLSIE------CPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC--------DSKTKKPSLLIK--------TFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEALEIKISPILVESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNI-LLKFPI 1538
            +CP+ +++C +  TCC     SY CC Y++AVCC DK HCCP  T C+     C+  ++   + ++     +++P I    ++      CP+  + C+   TCC+   GSY CC F+NAVCC DK  CCP+ + C+     C        + +   P+L ++          + N  + V+CP  K +C D +TCC +   ++Y CCP+              + TV NI                         CPN  + C ++ TCC + ++SY CC Y NAVCC D  HCCPN TSC    K C++NI   K PI
Sbjct:   45 ICPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPIQTTPEPMEMPVIEETDVKIITDQTCPNNRTKCQDSQTCCVTKHGSYHCCKFANAVCCPDKFHCCPEGSTCDAKQHKCVKCAKSNVEMRKLIPALKVEDEPKTNILEAKVNEKDEVMCPNNKTKCKDIKTCC-ITKHNNYYCCPHKNN-----------KETVGNI-------------------------CPNKRTKCTERQTCCQTKHNSYHCCKYANAVCCPDKFHCCPNGTSCDSVHKKCNRNIEATKSPI 326          
BLAST of Granulin b vs. Planmine SMEST
Match: SMESG000018770.1 (SMESG000018770.1)

HSP 1 Score: 206.838 bits (525), Expect = 1.547e-60
Identity = 133/395 (33.67%), Postives = 194/395 (49.11%), Query Frame = 3
Query:  444 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKL----------KEVVTKMKLKVPASSIL-------------SVVCP-DQSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------DSKLKEVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRV--ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDH---------QAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSC 1487
            VCP+ +++C +  TCC     SY CC Y +A+CC DK HCCP  + C+     C   +          + +  KM    P+S++               + CP ++++C D  TCC    G+Y CCP+ +AVCCSDK +CCP+NT C+L    C           +  LK         +  +  L  +CP+    C     CC +S G +GCC F+  +CC D  +CCP NT C+ +   C SK+   + +    QP    ++  ICP    +C   +TCC +  G  YGCCP+  ATCCSD   CCP N VC++ K  C +         ++++L    S I ++ I CP+ + C     CC   ++ Y CC Y N VCC+D   CCPN T C
Sbjct:   33 VCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSSAVFNSYKNPGLKSANLYTFYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTEIPNELQPEAQIKLNNICPDKHVECQSFETCCSVGDG-LYGCCPFKNATCCSDNASCCPHNKVCDLEKKVCKNKETSQPSITKSKSLLHFYSEIGLKVI-CPDQTKCENDSVCCQMDDNQYGCCSYKNGVCCADKQTCCPNGTQC 425          

HSP 2 Score: 202.986 bits (515), Expect = 4.563e-59
Identity = 144/431 (33.41%), Postives = 211/431 (48.96%), Query Frame = 3
Query:  105 FIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNXXXXXXXXXXXXXXVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDS---------VLKEVVTKIKLKVPASSIL--------------SVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC-----------DSKLKEVVTKMKLKVPASSILSVVCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLKEVVT-KMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTCDSK-TKKPSLL----IKTFQPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVC 1271
             I  +++   +   ++ F++     ++E N+     V   + + C +  +CCVT   SY CC Y +A+CC DK HCCP  + C+  K  C           V++E +    L +  SS L               + CP+ +++C D  TCC    G+Y CCP+ +AVCCSDK +CCP+NT C+L    C           +  LK         +     L   CP+ + QC     CC ++GG + CC ++  +CC D + CCP NT C+     C SK  ++     +L+  A   L+  CPD    C++  TCC + DG YGCCPF NA CCSD  SCCP N VC+L    C +K T +PS+     +  F      +VICP  + +C +   CC++   + YGCC Y    CC+DK  CCP  T C
Sbjct:    1 MILTIIVDYALTDGIFSFNKASQDQVSEKNE----NVCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSSAVFNSYKNPGLKSANLYTFYSLLNVDKLEKKCPNSEKQCPGQKKCCPMSGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTEIPNELQPEAQIKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVCKNKETSQPSITKSKSLLHFYSEIGLKVICPD-QTKCENDSVCCQM-DDNQYGCCSYKNGVCCADKQTCCPNGTQC 425          

HSP 3 Score: 154.451 bits (389), Expect = 3.201e-41
Identity = 113/332 (34.04%), Postives = 161/332 (48.49%), Query Frame = 3
Query:  672 VCPD-QSQCNDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTC----DSKLKEVVTKMKLKIPAIS-------------------NLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAVCCSDKLSCCPQNTVCNLSAGTC-DSKT-----KKPSL----LIKTFQPNPVNRV--ICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEAL-----EIKISPILVESIKCPNGSL-CGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSCDKNILLKFPII 1541
            VCP+ +++C +  TCC     SY CC Y +A+CC DK HCCP  + C+     C    +  ++  V +  L +  +                    N  I CP+  + CK   TCC+   G+Y CCP  NAVCCSDK +CCP+NT C+L    C DS       K P L    L   +    V+++   CP ++ QC   + CC + +G  +GCC ++   CC D   CCP NT C+  K  C  ++  L     E++    +  +  CP+  + C    TCC   +  Y CCP+ NA CCSD++ CCP+N  C L  K C KN     P I
Sbjct:   33 VCPNNRTKCKETQTCCVTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKCLDSSAVFNSYKNPGLKSANLYTFYSLLNVDKLEKKCPNSEKQCPGQKKCCPM-SGGHFGCCKFNKGICCPDMKTCCPHNTDCDSAKKACVSKSSDLTEIPNELQPEAQIKLNNICPDKHVECQSFETCCSVGDGLYGCCPFKNATCCSDNASCCPHNKVCDLEKKVC-KNKETSQPSI 362          

HSP 4 Score: 87.8113 bits (216), Expect = 2.680e-18
Identity = 59/163 (36.20%), Postives = 77/163 (47.24%), Query Frame = 3
Query: 1104 QPNPVNRVICPGAKYQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCDHQAEA---------------LEIKISPILV------------ESIKCPNG-SLCGQKGTCCPSANDSYSCCPYPNAVCCSDHSHCCPNNTSCSLNTKSC 1508
            Q +  N  +CP  + +C + QTCC +   +SY CC Y  A CC DK HCCP  + C+  K  C    E                L++K S  L             + I CPN  + C    TCC + + +Y CCP+ NAVCCSD  +CCP NT C L  K C
Sbjct:   25 QVSEKNENVCPNNRTKCKETQTCC-VTKHNSYHCCRYPNAICCPDKYHCCPSGSTCDAAKKRCTRNVEGPMEWPVVEENLPVKMLDLKPSSTLHGFESNSETLRVNDDITCPNNKTKCKDTKTCCITKHGNYYCCPHKNAVCCSDKYNCCPENTKCDLKNKKC 186          
The following BLAST results are available for this feature:
BLAST of Granulin b vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GRN1.961e-8036.75granulin precursor [Source:HGNC Symbol;Acc:HGNC:46... [more]
GRN1.278e-6936.22granulin precursor [Source:HGNC Symbol;Acc:HGNC:46... [more]
GRN2.161e-6338.11granulin precursor [Source:HGNC Symbol;Acc:HGNC:46... [more]
GRN4.125e-5833.08granulin precursor [Source:HGNC Symbol;Acc:HGNC:46... [more]
GRN4.012e-1531.13granulin precursor [Source:HGNC Symbol;Acc:HGNC:46... [more]
back to top
BLAST of Granulin b vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
pgrn-12.853e-2630.97ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:... [more]
pgrn-18.753e-2543.41ProGRaNulin homolog [Source:UniProtKB/TrEMBL;Acc:... [more]
back to top
BLAST of Granulin b vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Granulin b vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grnb2.026e-8537.84granulin b [Source:ZFIN;Acc:ZDB-GENE-030131-7393][more]
grna1.615e-7837.18granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
grna1.807e-7836.63granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
grna5.462e-7836.91granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
grna2.309e-4238.10granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
back to top
BLAST of Granulin b vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4
Match NameE-valueIdentityDescription
trappc111.338e-6836.67trafficking protein particle complex 11 [Source:Xe... [more]
trappc114.931e-6736.82trafficking protein particle complex 11 [Source:Xe... [more]
trappc111.295e-6636.82trafficking protein particle complex 11 [Source:Xe... [more]
trappc116.987e-6334.20trafficking protein particle complex 11 [Source:Xe... [more]
back to top
BLAST of Granulin b vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Grn1.905e-8037.28granulin [Source:MGI Symbol;Acc:MGI:95832][more]
Grn6.163e-2728.89granulin [Source:MGI Symbol;Acc:MGI:95832][more]
Grn1.666e-2538.12granulin [Source:MGI Symbol;Acc:MGI:95832][more]
Grn2.154e-2235.06granulin [Source:MGI Symbol;Acc:MGI:95832][more]
back to top
BLAST of Granulin b vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P28799|GRN_HUMAN9.415e-8036.75Progranulin OS=Homo sapiens OX=9606 GN=GRN PE=1 SV... [more]
sp|P28798|GRN_MOUSE9.720e-8037.28Progranulin OS=Mus musculus OX=10090 GN=Grn PE=1 S... [more]
sp|P23785|GRN_RAT2.527e-7936.78Progranulin OS=Rattus norvegicus OX=10116 GN=Grn P... [more]
sp|P28797|GRN_CAVPO2.750e-6433.55Progranulin OS=Cavia porcellus OX=10141 GN=GRN PE=... [more]
sp|Q54QR7|GRN_DICDI7.818e-1147.69Granulin OS=Dictyostelium discoideum OX=44689 GN=g... [more]
back to top
BLAST of Granulin b vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
K1PAM62.109e-10341.78Uncharacterized protein OS=Crassostrea gigas OX=29... [more]
A0A2G8L0S45.248e-10043.52Putative fibrillin-1 isoform X4 (Fragment) OS=Stic... [more]
A0A2B4SIQ66.825e-9944.62Granulin OS=Stylophora pistillata OX=50429 GN=GRN ... [more]
W4Z7544.197e-9844.78Uncharacterized protein OS=Strongylocentrotus purp... [more]
A0A2G8KIP69.205e-9744.55Putative kielin/chordin-like protein isoform X1 OS... [more]
back to top
BLAST of Granulin b vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grnb6.401e-8438.81granulins-like [Source:NCBI gene;Acc:103046308][more]
grnb6.401e-8438.81granulins-like [Source:NCBI gene;Acc:103046308][more]
grna5.242e-7935.81granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
grna7.135e-7835.61granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
grna1.793e-7735.61granulin a [Source:ZFIN;Acc:ZDB-GENE-030131-8434][more]
back to top
BLAST of Granulin b vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000009302.11.296e-9843.24pep scaffold:Pmarinus_7.0:GL483232:1183:11161:1 ge... [more]
ENSPMAT00000001039.11.623e-4933.33pep scaffold:Pmarinus_7.0:GL484091:11570:24665:-1 ... [more]
back to top
BLAST of Granulin b vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of Granulin b vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO278241.649e-3738.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of Granulin b vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
grnb6.554e-8638.41granulin precursor [Source:NCBI gene;Acc:101166910... [more]
grna1.814e-8439.95granulins [Source:NCBI gene;Acc:101162601][more]
grna2.406e-8339.73granulins [Source:NCBI gene;Acc:101162601][more]
ENSORLT00000029765.19.957e-2430.04granulins [Source:NCBI gene;Acc:101168633][more]
ENSORLT00000005071.21.032e-2330.04granulins [Source:NCBI gene;Acc:101168633][more]
back to top
BLAST of Granulin b vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000029882.19.475e-5298.36SMESG000029882.1[more]
SMESG000018760.13.013e-6531.65SMESG000018760.1[more]
SMESG000018760.18.356e-6129.98SMESG000018760.1[more]
SMESG000018760.18.669e-6129.98SMESG000018760.1[more]
SMESG000018770.11.547e-6033.67SMESG000018770.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035642 ID=SMED30035642|Name=Granulin b|organism=Schmidtea mediterranea sexual|type=transcript|length=1667bp
CAAATGTTGCTTATATATAAGTTAGCTTTATTTTAAAATTCCAAATTAGT
TGGTATTCATAATTGATATTACTTCTTTAAAATTTAGCTGCAAATATGTG
GAAATTTATTTTTGTAGTACTAATATCTTCGGTTGTCTGCCATGATGTTT
ACAGATTTAGTCGTGAATTTATCAAACCCATTACAGAAACAAATAAAATA
CCGGCGAAAGTAGTCAATTGTCCAGATGATTCTGTATGTGATGATGGGTC
ATCATGCTGTGTAACGACCGATGGAAGCTACTCATGTTGTCCATACTCAT
CAGCGGTTTGCTGCTCTGATAAGCAGCATTGTTGCCCACAAAACACTGAG
TGTAATTTGAATAAAGGAACTTGTGATTCTGTATTGAAGGAAGTAGTTAC
AAAAATAAAACTCAAAGTTCCAGCCTCTTCAATTCTTTCCGTGGTATGTC
CAGATCAATCTCAGTGTAATGATGGTTCAACATGCTGTGCAGTAGCTGGA
GGATCTTACGCATGTTGCCCATATTCATCAGCGGTCTGTTGTTCTGATAA
ACGTCATTGTTGTCCACAGAATACTGTATGCAATTTAGATGCTGGCACTT
GTGATTCGAAATTGAAGGAAGTGGTCACAAAAATGAAGCTCAAAGTTCCA
GCATCTTCAATTCTTTCCGTGGTATGTCCAGATCAATCTCAGTGTAATGA
TGGTTCAACATGCTGTGCAGTAGCTGGAGGATCTTACGCATGTTGCCCAT
ATTCATCAGCGGTCTGTTGTTCTGATAAACGTCATTGTTGTCCACAGAAT
ACTGTATGCAATTTAGATGCTGGCACTTGTGATTCGAAATTGAAGGAAGT
GGTCACAAAAATGAAGCTTAAAATTCCTGCCATTTCAAATCTTTCCATCG
AATGTCCAGATGGGTCATCGACATGTAAAACTGGAGCTACGTGTTGTCTA
TTATCTGACGGTAGCTATGGATGTTGTCCATTCTCCAATGCCGTATGTTG
TAGCGATAAGTTGAGTTGCTGCCCACAGAATACTGTTTGTAATTTATCTG
CTGGCACTTGTGATTCGAAAACCAAAAAGCCGAGCTTATTGATAAAAACA
TTCCAACCGAATCCAGTGAACCGAGTAATTTGTCCGGGTGCGAAATATCA
GTGCAGTGATGGTCAGACCTGTTGCAAATTACCTGCCGGTGATTCCTATG
GATGTTGCCCGTATTCTGCCGCTACGTGTTGTTCCGATAAAATTCATTGC
TGTCCTCAAAATACTGTTTGTAATATAAATAAGGGAACTTGTGATCACCA
AGCTGAAGCATTGGAGATTAAAATTTCCCCGATTTTAGTTGAATCTATCA
AATGCCCTAACGGAAGCCTGTGTGGACAGAAAGGTACATGTTGTCCATCT
GCTAACGACAGCTACAGTTGTTGTCCGTATCCTAATGCCGTCTGCTGCAG
CGATCACAGCCATTGTTGCCCTAATAACACGTCATGCAGCCTCAACACGA
AATCCTGTGACAAAAATATTTTATTGAAATTCCCTATTATAAATTTCCAT
CCATAATTTAACTATTATTTATTTGTTTTTACTTGATGTTGATTTTGTTA
AACTTTGTATTATTGATTAATTTTTCACATTGATTTTAATAAAAAATTAA
TTTTTTTTAAAAAAAAA
back to top

protein sequence of SMED30035642-orf-1

>SMED30035642-orf-1 ID=SMED30035642-orf-1|Name=SMED30035642-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=487bp
MWKFIFVVLISSVVCHDVYRFSREFIKPITETNKIPAKVVNCPDDSVCDD
GSSCCVTTDGSYSCCPYSSAVCCSDKQHCCPQNTECNLNKGTCDSVLKEV
VTKIKLKVPASSILSVVCPDQSQCNDGSTCCAVAGGSYACCPYSSAVCCS
DKRHCCPQNTVCNLDAGTCDSKLKEVVTKMKLKVPASSILSVVCPDQSQC
NDGSTCCAVAGGSYACCPYSSAVCCSDKRHCCPQNTVCNLDAGTCDSKLK
EVVTKMKLKIPAISNLSIECPDGSSTCKTGATCCLLSDGSYGCCPFSNAV
CCSDKLSCCPQNTVCNLSAGTCDSKTKKPSLLIKTFQPNPVNRVICPGAK
YQCSDGQTCCKLPAGDSYGCCPYSAATCCSDKIHCCPQNTVCNINKGTCD
HQAEALEIKISPILVESIKCPNGSLCGQKGTCCPSANDSYSCCPYPNAVC
CSDHSHCCPNNTSCSLNTKSCDKNILLKFPIINFHP*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: biological process
TermDefinition
GO:0048675axon extension
GO:0006614SRP-dependent cotranslational protein targeting to membrane
GO:0007165signal transduction
GO:0043312neutrophil degranulation
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR037277Granulin_sf
IPR039036Granulin_fam
IPR004125Signal_recog_particle_SRP54_M
IPR000118Granulin
Vocabulary: molecular function
TermDefinition
GO:00083127S RNA binding
GO:0003723RNA binding
GO:0005125cytokine activity
GO:0005515protein binding
GO:0008083growth factor activity
Vocabulary: cellular component
TermDefinition
GO:0048500signal recognition particle
GO:0005576extracellular region
GO:0005615extracellular space
GO:0005764lysosome
GO:0005768endosome
GO:0005783endoplasmic reticulum
GO:0035578azurophil granule lumen
GO:0070062extracellular exosome
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000118GranulinSMARTSM00277GRAN_2coord: 270..322
e-value: 2.0E-20
score: 83.8
coord: 42..93
e-value: 1.2E-14
score: 64.6
coord: 118..169
e-value: 5.5E-18
score: 75.8
coord: 346..399
e-value: 7.3E-20
score: 82.0
coord: 420..471
e-value: 1.1E-11
score: 54.8
coord: 194..245
e-value: 2.8E-21
score: 86.7
IPR000118GranulinPFAMPF00396Granulincoord: 53..93
e-value: 4.6E-13
score: 49.3
coord: 205..245
e-value: 2.2E-13
score: 50.3
coord: 129..169
e-value: 4.2E-13
score: 49.4
coord: 431..471
e-value: 1.2E-12
score: 48.0
coord: 282..322
e-value: 3.1E-14
score: 53.0
coord: 358..399
e-value: 3.7E-13
score: 49.6
IPR000118GranulinPROSITEPS00799GRANULINScoord: 379..392
IPR000118GranulinPROSITEPS00799GRANULINScoord: 225..238
IPR000118GranulinPROSITEPS00799GRANULINScoord: 149..162
IPR000118GranulinPROSITEPS00799GRANULINScoord: 451..464
IPR000118GranulinPROSITEPS00799GRANULINScoord: 73..86
IPR037277Granulin superfamilyGENE3DG3DSA:3.10.20.500coord: 416..479
e-value: 8.7E-17
score: 63.0
coord: 191..258
e-value: 2.2E-18
score: 68.1
coord: 115..182
e-value: 2.1E-17
score: 65.0
coord: 343..410
e-value: 2.3E-17
score: 64.9
coord: 38..105
e-value: 5.3E-17
score: 63.7
IPR037277Granulin superfamilyGENE3DG3DSA:3.10.20.500coord: 266..326
e-value: 2.6E-17
score: 64.8
IPR039036Granulin familyPANTHERPTHR12274GRANULINcoord: 268..403
coord: 35..256
coord: 337..474
NoneNo IPR availablePRODOMPD968187coord: 119..467
e-value: 6.0E-7
score: 131.0
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..15
score: 0.74
NoneNo IPR availableSUPERFAMILYSSF57277Granulin repeatcoord: 40..67
NoneNo IPR availableSUPERFAMILYSSF57277Granulin repeatcoord: 270..297
NoneNo IPR availableSUPERFAMILYSSF57277Granulin repeatcoord: 116..144
NoneNo IPR availableSUPERFAMILYSSF57277Granulin repeatcoord: 192..220