Peptidase M60 domain-containing protein

Overview
NamePeptidase M60 domain-containing protein
Smed IDSMED30035615
Length (bp)2834
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Peptidase M60 domain-containing protein (SMED30035615) t-SNE clustered cells

Violin plots show distribution of expression levels for Peptidase M60 domain-containing protein (SMED30035615) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035615

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30035615h1SMcG0015034 SmedASXL_015174SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30035615h1SMcG0015034 dd_Smed_v6_3759_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017		whole organism asexual adult RNA-sequencing evidence
head regionSMED30035615h1SMcG0015034 OX_Smed_1.0.10372ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF1 (TRPM8 channel associated factor 1 [Source:HGNC Symbol;Acc:HGNC:22201])

HSP 1 Score: 145.976 bits (367), Expect = 4.936e-35
Identity = 105/426 (24.65%), Postives = 199/426 (46.71%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQ----VVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+P L      + +EV      TR   +  G Y+P  + ++  +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  P++  L E+ + +W    +++ G W ++A ++++    +  LR  +    + L+  WD V++         +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G ++  W  +A+  L  Y+Q+   FG+  F + F  Y N   L  + + +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYK-LGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTE-NVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLA----YLPE 905
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF1 (TRPM8 channel associated factor 1 [Source:HGNC Symbol;Acc:HGNC:22201])

HSP 1 Score: 145.591 bits (366), Expect = 5.952e-35
Identity = 105/426 (24.65%), Postives = 199/426 (46.71%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQ----VVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+P L      + +EV      TR   +  G Y+P  + ++  +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  P++  L E+ + +W    +++ G W ++A ++++    +  LR  +    + L+  WD V++         +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G ++  W  +A+  L  Y+Q+   FG+  F + F  Y N   L  + + +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYK-LGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTE-NVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLA----YLPE 905
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2C (TRPM8 channel associated factor 2C [Source:HGNC Symbol;Acc:HGNC:53641])

HSP 1 Score: 128.642 bits (322), Expect = 6.873e-30
Identity = 87/367 (23.71%), Postives = 171/367 (46.59%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            +  G YL  G+  +  +  +    G  + +GCH+D L + R +  R P +         E ++   +GG+L+++    ++   + + +   V  P++  L ++++ +W    +++   W ++A ++++    +  L+       + ++  WD +++     A   +   RP + V D+  S G+ HSGYP+  + +    I +   ++ +G WG  HELGHNQQ +H W      +EAT N++ ++       +P   + + L     +  IK++L  GA L  W  + +  L  Y+Q+   FG+  F + F  Y     L  D +  + +LW    S    +NL+P F+ W  PI  E+   L+  
Sbjct:  338 VSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKAR-KLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYK-LGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDP--EPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQ-WHGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQQAFGWEPFTQLFAEYQTLSHLPKD-NTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASL 696
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2 (TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878])

HSP 1 Score: 128.257 bits (321), Expect = 1.252e-29
Identity = 87/367 (23.71%), Postives = 170/367 (46.32%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            +  G YL  G+  +  +  +    G  + +GCH+D L + R +  R P +         E ++   +GG+L+++    ++   + + +   V  P++  L ++++ +W    +++   W ++A ++++    +  L+       + ++  WD +++     A   +   RP + V D+  S G+ HSGYP+  + +    I +   ++ +G WG  HELGHNQQ  H W      +EAT N++ ++       +P   + + L     +  IK++L  GA L  W  + +  L  Y+Q+   FG+  F + F  Y     L  D +  + +LW    S    +NL+P F+ W  PI  E+   L+  
Sbjct:  441 VSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKAR-KLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYK-LGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDP--EPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQR-HGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPKD-NTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASL 799
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Match: TCAF2 (TRPM8 channel associated factor 2 [Source:HGNC Symbol;Acc:HGNC:26878])

HSP 1 Score: 128.257 bits (321), Expect = 1.252e-29
Identity = 87/367 (23.71%), Postives = 170/367 (46.32%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            +  G YL  G+  +  +  +    G  + +GCH+D L + R +  R P +         E ++   +GG+L+++    ++   + + +   V  P++  L ++++ +W    +++   W ++A ++++    +  L+       + ++  WD +++     A   +   RP + V D+  S G+ HSGYP+  + +    I +   ++ +G WG  HELGHNQQ  H W      +EAT N++ ++       +P   + + L     +  IK++L  GA L  W  + +  L  Y+Q+   FG+  F + F  Y     L  D +  + +LW    S    +NL+P F+ W  PI  E+   L+  
Sbjct:  441 VSTGLYLLEGQNAEVSLSEAAASAGLRVQIGCHTDDLTKAR-KLSRAPVVTHQCWMDRTERSVSCLWGGLLYVIVPKGSQLGPVPVTIRGAVPAPYYK-LGKTSLEEWKRQMQENLAPWGELATDNIILTVPTTNLQALKDP--EPVLRLWDEMMQAVARLAAEPFPFRRPERIVADVQISAGWMHSGYPIMCHLESVKEIINEMDMRSRGVWGPIHELGHNQQR-HGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHEALSPPERERRIKAHLGKGAPLCDW--NVWTALETYLQLQEAFGWEPFTQLFAEYQTLSHLPKD-NTGRMNLWVKKFSEKVKKNLVPFFEAWGWPIQKEVADSLASL 799
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-210b2.4 (si:ch211-210b2.4 [Source:ZFIN;Acc:ZDB-GENE-131122-12])

HSP 1 Score: 132.494 bits (332), Expect = 5.344e-31
Identity = 108/401 (26.93%), Postives = 173/401 (43.14%), Query Frame = 2 
Query: 1445 DLFPMDFKSAPKLEQVVLEVFGEIAYTR-----IPIGYYLPAGETLKYKIQAST--GQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPL-SEEGTIFSPFGGVLWLVNSNENA--SISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKEL-LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            DL P   K  P L  V        A T      I  G YL  G      I       +W + +GC +D +G  R +  +   +     PL SE+  + + +GG+++ V   ++    + I +   V  P+F    E++V+DW    R+    WA++  E++V    SD +R  +      + E WD ++R+    A    +  R  + V D+  S G+ HSGYP+         + +     +   WG  HELGHNQQ   +W      +E T N++ ++   K   +    +   + L+     IK Y  GG DL  W ++  LE   Y+Q+   FG+  F K F  Y +  ++  D +  K +L+A   S + N NL P F  W  PI     + LS  
Sbjct:  509 DLLPYIIKDRPNLPTVSNARVRITANTAGCEEWISTGLYLSPGMKTYITIPPEIIEKKWQVQLGCQTDDIG--RLKILKRAPVVHEQFPLDSEKVQVCNLWGGLIYFVAPPKSKVDGVEIVVQTAVQAPYFKS-GETSVADWVGKIRQRPAPWAELEFENLVMTLPSDLIRNLERP--DEVAELWDAIMRSVSDLAATPAKFPRKERFVGDVQISAGFMHSGYPIMMLSSSASQLLNVKEAHKHDFWGPLHELGHNQQR-KVWEFPPHTTECTCNLWSVYVHEKVLGVNRAKAHPCMTLESRQACIKKYFSGGKDLKNWTKATALE--TYMQLQEKFGWDAFKKVFSLYHDMKDVPND-NAGKMNLYAKTFSKVVNHNLSPFFKTWGWPIQPNTEQELSHL 900
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-210b2.2 (si:ch211-210b2.2 [Source:ZFIN;Acc:ZDB-GENE-131118-33])

HSP 1 Score: 129.028 bits (323), Expect = 5.442e-30
Identity = 99/368 (26.90%), Postives = 164/368 (44.57%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKIQAST--GQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPL-SEEGTIFSPFGGVLWLVNSNENA--SISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKEL-LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            I  G YL  G      I       +W + +GC +D +G   S   +   +     PL SE+  + + +GG+++ V   E+    + I +   V  P+F    E++V+DW    R+    WA++  E++V    SD +R  +      + + WD ++R+    A    +  R  + V D+  S G+ HSGYP+         + +     +   WG  HELGHNQQ   +W      +E T N++ ++   K   +    +   + L+     IK Y  GG DL  W ++  LE   Y+Q+   FG+  F K F  Y +  ++  D +  K +L+A   S + N NL P F +W  PI     + LS  
Sbjct:  538 ISTGLYLSPGMKTYITIPPEIIGTKWQVQLGCQTDNIGG--SNVLKRAPVVHERFPLDSEKVQVCNLWGGLIYFVAPPESKVDGVEIVVQTAVQAPYFKS-GETSVADWVGKIRQRPAPWAELEFENLVMTLPSDFIRNLERP--DEVAKLWDAIMRSVSDLAATPAKFRRKERFVGDVQISAGFMHSGYPIMMLSSSASQLLNVKEAHKHDFWGPLHELGHNQQR-KVWEFPPHTTECTCNLWSVYVHEKVLGVNKAKAHPCMTLESRQACIKKYFSGGKDLKNWTKATALE--TYMQLQEKFGWDAFKKVFSLYHDMKDVPND-NAGKMNLYAKTFSKVVNHNLSPFFKVWGWPIQPNTEQELSHL 896
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:162193 (zgc:162193 [Source:NCBI gene;Acc:323315])

HSP 1 Score: 124.405 bits (311), Expect = 1.499e-28
Identity = 88/342 (25.73%), Postives = 156/342 (45.61%), Query Frame = 2 
Query: 1598 WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENA--SISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            W + +GC +D +G   +   R P ++      SE   +++ +GG+++L+  ++     + I +   V  P+F    E++V+DW  + R+    WA++  E+++    S  +R  D      + + WD ++R     A    +  R  + V D+  S G+ H+GYP+  +      + +     + G WG  HELGHNQQ   +W      +E T N++ L+   + + +    +   +   +     K Y DGG DL  W    ++ L  Y+Q+   FG+  F K F  Y +   +  D +  K +L+A   S + N NL P F  W  PI     + LS  
Sbjct:  567 WQVQLGCQTDNIGGSNT-LKRAPVVHARFPLDSEMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQTAVQAPYFKS-GETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRP--DEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPIMMHSGSAPGLVNVEEAYKCGLWGAIHELGHNQQR-GVWEFPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSW--CMWMALETYMQLQEKFGWDAFKKVFSLYHDMTGVPND-NAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHL 900
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:162193 (zgc:162193 [Source:NCBI gene;Acc:323315])

HSP 1 Score: 124.405 bits (311), Expect = 1.499e-28
Identity = 88/342 (25.73%), Postives = 156/342 (45.61%), Query Frame = 2 
Query: 1598 WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENA--SISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            W + +GC +D +G   +   R P ++      SE   +++ +GG+++L+  ++     + I +   V  P+F    E++V+DW  + R+    WA++  E+++    S  +R  D      + + WD ++R     A    +  R  + V D+  S G+ H+GYP+  +      + +     + G WG  HELGHNQQ   +W      +E T N++ L+   + + +    +   +   +     K Y DGG DL  W    ++ L  Y+Q+   FG+  F K F  Y +   +  D +  K +L+A   S + N NL P F  W  PI     + LS  
Sbjct:  567 WQVQLGCQTDNIGGSNT-LKRAPVVHARFPLDSEMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQTAVQAPYFKS-GETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRP--DEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPIMMHSGSAPGLVNVEEAYKCGLWGAIHELGHNQQR-GVWEFPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSW--CMWMALETYMQLQEKFGWDAFKKVFSLYHDMTGVPND-NAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHL 900
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Match: zgc:162193 (zgc:162193 [Source:NCBI gene;Acc:323315])

HSP 1 Score: 124.405 bits (311), Expect = 1.499e-28
Identity = 88/342 (25.73%), Postives = 156/342 (45.61%), Query Frame = 2 
Query: 1598 WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENA--SISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            W + +GC +D +G   +   R P ++      SE   +++ +GG+++L+  ++     + I +   V  P+F    E++V+DW  + R+    WA++  E+++    S  +R  D      + + WD ++R     A    +  R  + V D+  S G+ H+GYP+  +      + +     + G WG  HELGHNQQ   +W      +E T N++ L+   + + +    +   +   +     K Y DGG DL  W    ++ L  Y+Q+   FG+  F K F  Y +   +  D +  K +L+A   S + N NL P F  W  PI     + LS  
Sbjct:  567 WQVQLGCQTDNIGGSNT-LKRAPVVHARFPLDSEMVQVWNLWGGLIYLIAPSQTKVDGVEIVVQTAVQAPYFKS-GETSVADWVSHIRQAPAPWAELEFENLIMTFDSAFIRNLDRP--DEVAKLWDTIMRTITDLAARPPKLPRKERFVADVQISYGFMHAGYPIMMHSGSAPGLVNVEEAYKCGLWGAIHELGHNQQR-GVWEFPPHTTECTCNLWSLYVHEQVFGIKSANAHPAITPADRQARTKMYFDGGKDLNSW--CMWMALETYMQLQEKFGWDAFKKVFSLYHDMTGVPND-NAGKMNLYAQTFSKVVNLNLSPFFKAWGWPIQPNTEQNLSHL 900
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045101.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200])

HSP 1 Score: 140.584 bits (353), Expect = 2.080e-33
Identity = 103/364 (28.30%), Postives = 174/364 (47.80%), Query Frame = 2 
Query: 1538 GYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNEN--ASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            G YL   +T      AS  Q G  + VGCHSD LG K  E+YR P +        E+  +   +GG+L+++    +   +I + +      P + I  ++++  W ++ R     WA++  E+++    SD +R  +    + L+  WDR++      A +     RP + V D+  S G+ H+GYPV  +      + + + ++++G WG  HELGHNQQ+  +W      +EAT N++ +F       +P   +   L   +    I++YL  G  L  W  + +  L  Y+Q+   FG+  F + FK Y +   +  D ++ K +LWA   S     NL+P F+ W  PI +E R  LS  
Sbjct:  533 GLYLSPKKTAVLVFPASAVQQGLQVQVGCHSDDLGSK-DEFYRAPIVVRKISVHREKVQVSCYWGGLLYIIVKERSNLGTIPVQVYGAEPAPTY-IKGKTSLDSWLQSLRDLPPPWAELITENIILTVPSDAIRSLNDP--EELLGFWDRMMVAITELAAIPTTFSRPERIVADVQISAGWMHAGYPVMVHLASVKYLTNLSCMQKEGLWGPIHELGHNQQQ-KVWEFPPHTTEATCNLWSVFVNETVVGVPRDKANSALEPASRAACIEAYLKTGPKLENW--NVWTALETYLQLQEGFGWEPFKQLFKDYQSMSGISND-NKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEETRSKLSAL 888
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000002244.1 (TRPM8 channel-associated factor homolog [Source:NCBI gene;Acc:100489234])

HSP 1 Score: 135.576 bits (340), Expect = 6.462e-32
Identity = 123/489 (25.15%), Postives = 214/489 (43.76%), Query Frame = 2 
Query: 1184 DNYDYLLENGQFLLNSMNKM-PPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWL-VNSNEN-ASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD------EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEE--KYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            +N    L + Q  L S  K+  P      KL      F++     +  +   K  P +  S+ +++    L  KS  ++H      C DL  ++ + +     V ++     A      G YLP  + +  +  AS  Q G  + VGCHSD    K +   R P +        ++  + S +GG+L++ V SN N  ++ + +      P + I  ++++  W  + R+    WA++  E+++    SD +R       ++L+  WDR++      A    +  RP + V D+  S G+ H+GYP+    +    + D ++++++G WG  HELGHNQQ+         +EAT N++ ++       +P     ++   GN         IKSYL  GA+L  W    +  L  Y+Q+    G+  F + ++     P +   S+E   K +LWA   S     NL+P F+ W  PI    R  LS  
Sbjct:  404 NNCHRALHHLQVALKSGTKLLQPISTRMRKLRQNVSAFMRHSACCVPKVS--KTCPVSGCSEEALL--LSLAHKSHNMSHK-----CDDLSILEKEPS---VTVNIDATNPGADAWRSTGLYLPPRKAVVIEFPASAVQQGFQVQVGCHSDDPSAKET-LNRAPVVVRRIHVDRQKVPVSSFWGGLLYIIVRSNSNFGTVPVRVYGAEPAPIY-IKGKTSLDSWLHSIRQLPAPWAELVTENIILTVPSDAVRSLKNP--EALLSLWDRIMAAIADLAAKPKKFPRPERIVADVQISAGWMHAGYPIMCDLESAKELTDLHHMEKEGIWGPIHELGHNQQKTQWEFPPHTTEATCNLWAVYVHETVLGIP-----RDRAHGNLQPNVRTSRIKSYLQNGANLEQW--DGWTALETYLQLQEGLGWDPFRRLYR----DPSISGMSNENTFKMNLWAEKFSRAAQTNLVPFFEAWGWPIDQSTRSKLSAL 865
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045059.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200])

HSP 1 Score: 132.88 bits (333), Expect = 6.161e-31
Identity = 98/365 (26.85%), Postives = 173/365 (47.40%), Query Frame = 2 
Query: 1538 GYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWL-VNSNENASI-SIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLP---YYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            G YL   +T   +  AS  Q G  + VGC +D L     ++ R P +        ++ ++   +GG+L++ V +N N  I  + +      P + I  ++ +  W ++ R     WA++  E+++    SD +R       ++L+  WD+++ +    A +     RP + V D+  S G+ H+GYP+  + +    + D N ++  G WG  HELGHNQQ+ +       +EAT N++ ++       +P    +GS +      Y  I+ Y+  G++L  W    +  L  Y+Q+   FG+  F + FK Y +   +  D ++ K +LWA   S     NL+P F+ W  PI +E R  LS  
Sbjct:  533 GLYLAPRKTAVLEFPASVVQQGLKVQVGCQADDLSSAE-KYCRAPVVVRKCHVDRQKVSVSCFWGGLLYIIVKANSNLGIIPVKVYGAEPAPVY-IKGKTNLDSWLQSVRYLPAPWAELITENIILTVPSDAIRSLSDP--EALLSLWDKIMVSITELAAIPKTFPRPERFVADVQISAGWMHAGYPIMCHLESAKELTDLNVMQTVGIWGPIHELGHNQQKINWEFPPHTTEATCNLWSVYVHETVLGIPRNKAHGSLQPETRACY--IQEYVKNGSNLEQW--DVWTALETYLQLQEGFGWEPFKQLFKDYQSMSGISND-NKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEETRSKLSAL 888
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: suox (sulfite oxidase [Source:Xenbase;Acc:XB-GENE-985202])

HSP 1 Score: 130.568 bits (327), Expect = 2.896e-30
Identity = 95/369 (25.75%), Postives = 167/369 (45.26%), Query Frame = 2 
Query: 1538 GYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNEN--ASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELL-DGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
            G YL   +    +   S  Q G  + VGC +D L  K    +R P +        ++  + S +GG+L+++   ++    I + +      P + I  +++   W  + RK    WA++  E+++    SD +R       +SL+  WDR++      A ++    RP + V D+ TS G+ H+GYP+  +++    + D  ++++ G WG  HELGHNQQ          +EAT N++ ++       +P   +  +L  +     +K+YL GG+ L  W+   +  L  Y+Q+   FG+  F   F +         D +  K +LWA   S     NL+P F+ W  PI    R  +S    +  D
Sbjct:  536 GLYLAPRKAAVLEFPVSVVQQGFWVQVGCQTDDLSAKEM-LHRAPVVVRKIHVDCQKVAVSSLWGGLLYVIVRADSKLGPIPVRVYGAEPAPVY-IKGQTSPDSWLHSVRKLPAPWAELVTENIILTVPSDAVRSLTDP--ESLLSYWDRIMGAIAELAAIE-TFPRPERFVADVQTSAGWMHAGYPIMCHEESVKELTDLRHMQKNGMWGPIHELGHNQQRKEWEFPPHTTEATCNLWSVYVHEMVLGIPRDQAHPDLQPEARRSRLKAYLQGGSKLKNWE--VWTALETYLQLQEGFGWEPFKSLFGH---------DENTSKMNLWAEKFSWAMQTNLVPFFEAWGWPIDSVTRSSVSALPVWEAD 888
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000045084.1 (TRPM8 channel-associated factor 2 [Source:NCBI gene;Acc:100170200])

HSP 1 Score: 130.183 bits (326), Expect = 3.862e-30
Identity = 97/365 (26.58%), Postives = 172/365 (47.12%), Query Frame = 2 
Query: 1538 GYYLPAGETLKYKIQASTGQWG--ISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWL-VNSNENASI-SIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLP---YYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            G YL   +T   +  AS  Q G  + VGC +D L     ++ R P +        ++ ++   +GG+L++ V +N N  I  + +      P + I  ++ +  W ++ R     WA++  E+++    SD +R       ++L+  WD+++ +    A +     RP + V D+  S G+ H+GYP+  + +    + D N ++  G WG  HELGHNQQ+ +       +EAT N++ ++       +P    +GS +      Y  I+ Y+  G++L  W    +  L  Y+Q+   FG+  F + FK Y +   +  D ++ K +LWA   S     NL+P F+ W  PI +  R  LS  
Sbjct:  533 GLYLAPRKTAVLEFPASVVQQGLKVQVGCQADDLSSAE-KYCRAPVVVRKCHVDRQKVSVSCFWGGLLYIIVKANSNLGIIPVKVYGAEPAPVY-IKGKTNLDSWLQSVRYLPAPWAELITENIILTVPSDAIRSLSDP--EALLSLWDKIMVSITELAAIPKTFPRPERFVADVQISAGWMHAGYPIMCHLESAKELTDLNVMQTVGIWGPIHELGHNQQKINWEFPPHTTEATCNLWSVYVHETVLGIPRNKAHGSLQPETRACY--IQEYVKNGSNLEQW--DVWTALETYLQLQEGFGWEPFKRLFKDYQSMSGISND-NKSKMNLWAEKFSEAVQTNLIPFFEAWGWPIEEATRIKLSAL 888
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf1 (TRPM8 channel-associated factor 1 [Source:MGI Symbol;Acc:MGI:1914665])

HSP 1 Score: 139.813 bits (351), Expect = 2.795e-33
Identity = 103/428 (24.07%), Postives = 194/428 (45.33%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSA----PKLEQVVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDE--EKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+    P    + + V      TR   +  G Y+P  + +   +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  PF+  L E++  +W     ++ G W ++A ++++    +  LR  +    + L+  WD +++      G  +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G  +  W  +A+  L  Y+Q+   FG+  F + F  Y N     +   +  +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCTNPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYK-LGETSKEEWKRRLLEYPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLA----YLPE 908
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf1 (TRPM8 channel-associated factor 1 [Source:MGI Symbol;Acc:MGI:1914665])

HSP 1 Score: 139.813 bits (351), Expect = 2.795e-33
Identity = 103/428 (24.07%), Postives = 194/428 (45.33%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSA----PKLEQVVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDE--EKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+    P    + + V      TR   +  G Y+P  + +   +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  PF+  L E++  +W     ++ G W ++A ++++    +  LR  +    + L+  WD +++      G  +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G  +  W  +A+  L  Y+Q+   FG+  F + F  Y N     +   +  +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCTNPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYK-LGETSKEEWKRRLLEYPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLA----YLPE 908
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf1 (TRPM8 channel-associated factor 1 [Source:MGI Symbol;Acc:MGI:1914665])

HSP 1 Score: 139.813 bits (351), Expect = 2.795e-33
Identity = 103/428 (24.07%), Postives = 194/428 (45.33%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSA----PKLEQVVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDE--EKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+    P    + + V      TR   +  G Y+P  + +   +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  PF+  L E++  +W     ++ G W ++A ++++    +  LR  +    + L+  WD +++      G  +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G  +  W  +A+  L  Y+Q+   FG+  F + F  Y N     +   +  +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCTNPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYK-LGETSKEEWKRRLLEYPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLA----YLPE 908
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf3 (TRPM8 channel-associated factor 3 [Source:MGI Symbol;Acc:MGI:3042585])

HSP 1 Score: 129.798 bits (325), Expect = 4.271e-30
Identity = 97/368 (26.36%), Postives = 171/368 (46.47%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFS-PFGGVLWLVNSNE--NASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKEL-LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            +  G YLP G+  +  +  +A+  +  + +GCH D + + R+  Y  P + T    L+   T  S  +GG+L+++  N+    ++S+ +   V  P+F  L ++   +W       +  W ++A ++++    +  L++    Y   L++ WD++VR     A   +   R  + VLD   S G+ HSGYP+         I     I+  G WG+ HELGHN Q+   WT     +EA  N++ ++       +P   +   L  +     IK +L+ GA L+ W     LE   Y+Q+   FG+  F + F  Y     L  + +E+K +LW    S   ++NL P F+ W  P+   + K L+  
Sbjct:  536 VSTGLYLPEGQVAQVLLPSEATHAKLKVLIGCHRDNISQART--YFRPPVMTYVYHLTSSQTSISWLYGGLLYIMVPNKYNQDNVSVTIRGAVSAPYFR-LGKTTQEEWKNLITHSKAPWGELATDNIILTIPTVNLKELQDPY--PLLQLWDKMVRAVAKLAARPFPFQRAERVVLDKQISFGFLHSGYPIMGLISIVEGIISEFKIRSHGIWGVIHELGHNHQKSG-WTFPPHTTEALCNLWTIYVHETVLNIPREQAHPSLNPELRRQRIKYHLNKGAPLSNWIMWTALE--TYLQLQEGFGWEPFIQVFADYRTLSGLPQN-NEDKMNLWVKKFSEAVHKNLAPFFEAWGWPVKYAVAKSLASL 894
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Match: Tcaf2 (TRPM8 channel-associated factor 2 [Source:MGI Symbol;Acc:MGI:2385258])

HSP 1 Score: 125.946 bits (315), Expect = 6.007e-29
Identity = 88/363 (24.24%), Postives = 175/363 (48.21%), Query Frame = 2 
Query: 1538 GYYLPAGETLKYKIQ--ASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            G YL  G++ +  +   A++    + +GCH+D L     + +R P +         + ++   +GG+L+++     +   +S+ ++N V  P++  L ++++ +W    +K+ G W ++A ++++    +  L+  +    + L++ WD +++     A   +   RP + V D+  S G+ HSGYP+  + +    +     I+ KG WG  HELGHNQQ          +EAT N++ ++       +P   +  +L     ++ IK +L  GA L  W  + +  L  Y+Q+   FG+  F   F  Y     +  D +E K ++W  + S    +NL+P F+ W  PI  ++ + L+ +
Sbjct:  549 GLYLLEGQSTEISVSEPAASAGLKVQIGCHTDDL-TFAIKLFRAPVVTYQCCMNRTQRSVSCLWGGLLYIIVPKGCQLGPVSVTITNAVPAPYYK-LGKTSLEEWKSCIQKNLGPWGELATDNVILTVPTASLKTLENP--EPLLQLWDEMMQAVARLASQPFPFQRPERIVADVQLSAGWMHSGYPIMCHMESVQELVSLANIRSKGLWGPIHELGHNQQCRGWEFPPHTTEATCNLWSVYVHETVLGIPRAQAHPQLKPEEREKRIKEHLQKGAPLQNW--NVWTALETYLQLQEVFGWEPFITLFAEYQTIFYIPED-NECKMNIWLKLFSEKVQKNLVPFFEAWGWPIQKDVAEDLACY 904
[Close]
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q5R8R3|TCAF1_PONAB (TRPM8 channel-associated factor 1 OS=Pongo abelii OX=9601 GN=TCAF1 PE=2 SV=2)

HSP 1 Score: 147.517 bits (371), Expect = 8.523e-35
Identity = 106/426 (24.88%), Postives = 200/426 (46.95%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQ----VVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+P L      + +EV      TR   +  G Y+P  + ++  +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  P++  L E+ + +W  + +++ G W ++A ++++    +  LR  +    + L+  WD V++         +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G ++  W  +A+  L  Y+Q+   FG+  F + F  Y N   L  D + +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYK-LGETTLEEWKRHIQENPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTD-NVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVTTSLA----YLPE 905
[Close]
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|A5PJN5|TCAF1_BOVIN (TRPM8 channel-associated factor 1 OS=Bos taurus OX=9913 GN=TCAF1 PE=2 SV=1)

HSP 1 Score: 146.747 bits (369), Expect = 1.450e-34
Identity = 106/426 (24.88%), Postives = 198/426 (46.48%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQ----VVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+P L      + +EV      TR   +  G Y+P  + ++  +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   S++  ++ + +   V  P++  L E+   +W    +++ G W ++A ++++    +  LR  +    + L+  WD V++         +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G ++  W  +A+  L  Y+Q+   FG+  F + F  Y N   L  D + +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCNNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQSSKLGTVPVTIKGAVRAPYYK-LGETTQEEWKRQIQENPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRGRANIALWPPVREKRVRIYLGKGPNVKNW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTD-NVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLA----YLPE 905
[Close]
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y4C2|TCAF1_HUMAN (TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3)

HSP 1 Score: 145.591 bits (366), Expect = 2.858e-34
Identity = 105/426 (24.65%), Postives = 199/426 (46.71%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQ----VVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+P L      + +EV      TR   +  G Y+P  + ++  +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  P++  L E+ + +W    +++ G W ++A ++++    +  LR  +    + L+  WD V++         +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G ++  W  +A+  L  Y+Q+   FG+  F + F  Y N   L  + + +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLVPEIEDMYSSPYLRPSESPITVEVNCTNPGTRYCWMSTGLYIPGRQIIEVSLPEAAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPVTVKGAVHAPYYK-LGETTLEEWKRRIQENPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEVMQAVARLGAEPFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPNVKNW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTNLPTE-NVDKMNLWVKMFSHQVQKNLAPFFEAWAWPIQKEVATSLA----YLPE 905
[Close]
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8BNE1|TCAF1_MOUSE (TRPM8 channel-associated factor 1 OS=Mus musculus OX=10090 GN=Tcaf1 PE=2 SV=1)

HSP 1 Score: 139.813 bits (351), Expect = 2.015e-32
Identity = 103/428 (24.07%), Postives = 194/428 (45.33%), Query Frame = 2 
Query: 1388 GLFAKSQGLAHSKYKLPCIDLFPMDFKSA----PKLEQVVLEVFGEIAYTR---IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDE-IKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDE--EKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
             + + + GLAHS   L  +     D  S+    P    + + V      TR   +  G Y+P  + +   +   A++    I +GCH+D L  + S+ +R P +           +I   +GG+L+++   +++  S+ + +   V  PF+  L E++  +W     ++ G W ++A ++++    +  LR  +    + L+  WD +++      G  +    P + V D+  SVG+ H+GYP+  + +    + +   I+ KG WG  HELG NQQ          +EAT N++C++       +P   +   L     ++ ++ YL  G  +  W  +A+  L  Y+Q+   FG+  F + F  Y N     +   +  +K +LW  + S    +NL P F+ W  PI  E+   L+    +LP+
Sbjct:  491 AMLSLATGLAHSGSDLSLLIPEIEDVYSSRYLRPSASPITVNVNCTNPGTRYCWMSTGLYIPGRQVIDVSVPESAASADLKIQIGCHTDDL-TRASKLFRGPLVINRCCLDKPTKSITCLWGGLLYIIVPQNSKLGSVPLTVKGAVRAPFYK-LGETSKEEWKRRLLEYPGPWGELATDNIILTVPTANLRTLENP--EPLLRLWDEMMQAVAKLGGETFPLRLPQRIVADVQISVGWMHAGYPIMCHLESVQELINEKLIRTKGLWGPVHELGRNQQRQEWEFPPHTTEATCNLWCVYVHETVLGIPRSRANIALWPPVREKRVRIYLSKGPSVKHW--NAWTALETYLQLQEAFGWEPFIRLFTEYRNQTTSSSPPSDNVDKMNLWVKMFSQQVQRNLAPFFEAWGWPIQKEVATSLA----YLPE 908
[Close]
BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6P6V7|TCAF3_RAT (TRPM8 channel-associated factor 3 OS=Rattus norvegicus OX=10116 GN=Tcaf3 PE=2 SV=1)

HSP 1 Score: 130.954 bits (328), Expect = 1.302e-29
Identity = 97/385 (25.19%), Postives = 179/385 (46.49%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKI--QASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFS-PFGGVLWLVNSNE--NASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMST-VSEATNNIFCLFNTAKEWKLPYYGSTKEL-LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSRE 2662
            +  G YLP G+  +  +  +A+  +  + +GCH D + + ++  Y  P + T    L+   T  S  +GG+L+++  ++    ++S+ +S  V  P+F  L ++   +W       +  W ++A ++++    +  L+     Y   L++ WD++V+     A   +   RP + VLD   S G+ HSGYP+         I +   I+  G WG+ HELGHN Q+   WT     +EA  N++ ++       +P   +   L  +     IK +L+ GA L+ W    +  L  Y+Q+   FG+  F + F  Y     L  + +E+K +LW    S +  +NL P F  W  P+   + K L+    +  +   + ++ S E
Sbjct:  536 VSTGLYLPEGQVAQVTLPTEATHAKLKVLIGCHIDNISQAKT--YIRPPVMTYVYHLTSSQTSISWLYGGLLYIMVPDKYNQDNVSVTISGAVSAPYFR-LGKTTQEEWKNLIEHSKAPWGELATDNIILTIPTVNLKVLQDPY--PLLQLWDKIVKAVAKLAARPFPFQRPERIVLDKQISFGFLHSGYPIMGLIIIVEGIINEFKIRSHGVWGVTHELGHNHQKPG-WTFRPHTTEALCNLWSIYVHETVLNIPRDQAHPSLNPELRKQRIKDHLNKGAPLSNW--IVWTALETYLQLQEGFGWEPFIQLFANYQTLTGLPQN-NEDKMNLWVKKFSEVVQKNLAPFFKAWGWPVQHAVAKSLASLPEWQENPMKMYTAESTE 911
[Close]
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: A0A1S6KMG0 (Peptidase M60 domain-containing protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 1911.73 bits (4951), Expect = 0.000e+0
Identity = 920/924 (99.57%), Postives = 922/924 (99.78%), Query Frame = 2 
Query:    2 MFYRSILIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK 2773
            MFYRS LIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLL RGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKL+QVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTG+WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK
Sbjct:    7 MFYRSTLIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLARGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLKQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGKWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK 930
[Close]
BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: A0A1S6KMG4 (Peptidase M60 domain-containing protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0
Identity = 357/922 (38.72%), Postives = 533/922 (57.81%), Query Frame = 2 
Query:   17 ILIIALQIFILKALAAQE-NILLKKPAY-ANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMES-WDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLP-DDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKK 2770
            I I+   +F   +L+  + NILL K    A+DY  Y  N NDG+  T MW  S+N   I FDL   Y + K+I+ NG YR  +    Y+G+E + C     I+ Y  C   ++QN++   + C      GRY+ ++KG       +E L   +IE YG          +P + S  +   +++ F +A  +R N+P+  +  YS   + +N  CEPII+D   +L F  AC  ++ +G+ + F K  Y   +  D  + ++RT+ ++WL+ GN +P  + S   K +SD    +K G ++ F     +PD+++   K+LL  G +S+V +   +++   +   S  +I+N+FN+    T+ ++ S     + DS F++  + L+  L +++ N+DYLL     L   M+K P  ++ N+KL  +    +KKY+ L+ +ICPC    ATD++DR +I  FG   K+Q LA+S +K PC DLFP DF ++P    V L + G    T  PIGYYL AG TL+Y I  S+G W ISVGCH+D L +  + W RYP I    +P+S  G I+S FGGVLWL N    ++I+I LSNVV+TPFFN+ D +A S+WNE +R   G+W+QIAG+ +VFCE S RL+ FD QY+  LM + WD+ VR   V    DW+  RP  TVLD+M S GY HSGYPV  Y  WF ++F+S  I+  GSWGMCHE+GHN Q+   WT    +E TNN+ CLF  AK +K+P YG+    L  +   I +YL+GGA  + W  + +L L IY QM+ + G+GF+   F+YY +   +   +D EK   + N+TS I+ QN++ IFD W  PI + + + LS   CF P DDF +  S  R+ +I  KYP C+ KS+FY+D++P+    G RPNFI++
Sbjct:    5 IQILCFVVFAKISLSMSDTNILLNKTILVASDYPSYATNINDGNVKTCMWFESENKKMIAFDLGKTYKINKIIVRNGNYRATIEANFYIGNEFQACRFQTLIRTYGKCDP-LVQNNSTNELTCRDPSNVGRYLVLIKGNPFDYDPIERLYLCDIEVYGVESTNVAVPTRPVVDSSSLDPITKDFFKIAPIIRNNVPIATIPYYSSAVIYLNRNCEPIIYDNTTSLAFGVAC--ESGKGRMVAFAKSAYLRNMNLDPTQNQLRTNLLSWLTFGNPSPPTIISSQVKKMSDFYTLIKPGTVVYFDVWSSHPDDILNTWKALLLNGTVSMVVEITFWVSNTVEARNSYLQILNIFNVDFLNTFISWSSPINSEMPDSMFSDNLIGLEDILSRMLLNHDYLLSKASLLNGLMSKYPASMLNNSKLSVILIAIIKKYESLLKWICPCDVQKATDLNDRKLIRFFGELLKNQALAYSNFKAPCGDLFPGDFVASPPKVTVRLNLVGITPSTDNPIGYYLEAGSTLEYNIIVSSGSWAISVGCHTDNLPDSLAGWARYPSITVYRIPISGIGHIYSAFGGVLWLYNDVVGSNITIELSNVVVTPFFNLRDSNAASNWNE-RRYSPGIWSQIAGDSIVFCEESRRLKNFDSQYMVDLMRNIWDKAVRMEMVLTNTDWKIQRPQITVLDVMISAGYGHSGYPVELYQSWFDSVFNSTSIRTIGSWGMCHEVGHNLQKSK-WTFYGTTEVTNNLQCLFVYAKLFKIPRYGTDLSSLGSDTSTISAYLEGGAVFSQWTSNPWLALLIYSQMSQYLGWGFYKDLFEYY-DTNNISPSTDSEKMITFMNITSIISQQNMISIFDFWGFPIDNNLSQQLSTLPCFFPADDFLVALSPKRKNYISNKYPQCNSKSSFYKDYSPDLFINGMRPNFIQE 920
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BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: V4A0M8 (Peptidase M60 domain-containing protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_165593 PE=4 SV=1)

HSP 1 Score: 254.988 bits (650), Expect = 1.218e-67
Identity = 162/490 (33.06%), Postives = 249/490 (50.82%), Query Frame = 2 
Query: 1307 DYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEV--FGEIAYTRIPIGYYLPAGETLKYKIQASTGQ-WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIF-SPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVN------IFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYL-DGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLN-HPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKY-PDCHRKSTFY--EDFNPE 2731
            DY+ S  CP K             ++ GL      +      LP I  FP DF+S P    V L +  + E  +   P GYY+ AG++L   + +  G+ W + +G HSD L   +SE  R+P++     PL+E+ TI  + FGG+++  + +   SI++ L NV+  P F++   + +  WN  +R+  GLWA I  E ++    S  +R  DG    S+M+ WD V++ ++   G+D R +R    V D+  S GY HSGYPV T+ D   N      + +S+ +  KGSWG+ HE GHN QE  +WT    +E T NIF L   A +  +       E L       K YL     + + WK    + L IY Q+A+H G+G F + F+ Y   +P    + + ++ DLW  + S ++  NL  + D W IP+ D+ R+ +SKFQ FLPDD  ++ +  R   IL KY  +C R+  +   +DFN E
Sbjct:  472 DYVPSEHCPVKSSEGK--------ALIGLCETLNKMGKVNQILPGIANFPGDFESTPSKTSVTLTLSSYQEDVH---PTGYYVQAGDSLAVSVLSQNGKGWTVQIGAHSDCL-SGQSELKRWPNVVCCK-PLNEQCTIVKATFGGLVYFTSPSNQQSITVQLDNVIQAPLFDLTLPTTIEQWN-GRRQAPGLWADICSEFLIITLPSKSIRNLDGPV--SVMKKWDEVLKAHFHLKGIDIRNHRKQWLVTDVQPSAGYMHSGYPVVTHLD-VANPSHEFFLLNSHNLNTKGSWGVFHEFGHNMQE-GVWTFPGTTEVTVNIFTLH--AMDTLIGKRPIVHEWLQNQMSNAKRYLYHNDQNYSHWKSDPGIALFIYAQIAHHLGWGVFKEVFRRYGRMNPSSYPNKENDQIDLWYTLLSEVSQLNLASLVDFWKIPLSDKARREMSKFQPFLPDDDVMRMAPERTHMILAKYHSNCLRQPAYIVKDDFNTE 941
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BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: A0A448WAZ0 (Peptidase M60 domain-containing protein OS=Protopolystoma xenopodis OX=117903 GN=PXEA_LOCUS739 PE=4 SV=1)

HSP 1 Score: 240.736 bits (613), Expect = 1.275e-63
Identity = 191/733 (26.06%), Postives = 318/733 (43.38%), Query Frame = 2 
Query:  656 PIIWDVKWNLTFAFACYTDNKQGKALFFG-KEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNY-VNSENFKTISDVRGALKDGDILDFHTTVD--YPDEVIEEIKSLLTR---GKISLVFDHDSF-------IAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKV-RLRKLVDNYDY----LLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPC---------KDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAP----KLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKI---QASTGQ------WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQ-RKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLM-ESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFN-------TAKEWKLPYYGSTKEL---------------LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSR 2659
            P+ WD         A +    QG+A     ++W   ++    ++ +I  + + WL+     P   +  +N   +S  RGA  D  + +    V   YPD  +  +   + R   G+  L+     +       +A  +   R       +  +  DT Y     +  +T          LDL + R  + +  +D     L + GQ  L++  +   ++I++     +  + L +Y  L+ Y+ PC         +  P+  +  R  I  F     +  L ++  KLP +  FP DF + P    +  Q+ LEV   ++  +   G+Y PAG T +Y++   +   G       W + +GCH+D L E  + W R+P + T+ VPL   G +F+P GGV++L +S  ++ + IH   +      ++ D  ++SDW   + R +   W++I G+ + FC  +  +R     YL  L  ++WDRVV+ +Y F G  WR  R  +  LD+   VG  H+GYP+    +WF +I++   I+  GSWG+CHE+GHN Q    WTM   +E TNN+ CL N        + +  L    S K                 LD    E  SYL  G     W  S  + L  ++ + +HFG G  + A+  Y   P           D W  + S     +L+ + + W +P G      LSK  CFLPDD+  +    R
Sbjct:   17 PVCWDPVSRRVICAALHYG--QGRAFAVASQQWSSRFLEVPDERPDIHEAIMAWLTRVRARPRLSLPDDNRHIVSCRRGANLDQLLTEARRIVVIFYPDCTVSRLDEFVHRFRWGQFGLILAGAGWSMRTRRNLAFTQLADRLELTFPPVVVVPQDTAY----PASLFTRHQHGLGPVSLDLALMRATRSLALFDTAQPDLPDTGQ--LSAPQR---RLIQSESTSSLIANLLTRYSSLMDYVAPCPSRPFRGLTRGQPSLPLPHRHAILNFNRLVFAPSLRYTGLKLPGVSQFPGDFPTRPAHGLRTSQLFLEVNHTVSGEKHTTGFYAPAGATFEYEVAFVEPPGGSEDEPIGWSLEIGCHTDRL-EPLARWDRFP-VITHRVPLELHGVVFTPVGGVVFLSSSLSSSHLIIHFYGLQEHALMHLRDNLSLSDWAAGRWRYNLAPWSEILGDAVAFCLPTSLVRSASLDYLIRLTRDTWDRVVKADYNFRGDSWRSERRQRVTLDVQLMVGSGHNGYPIVGSLNWFDSIWNLTRIRAIGSWGLCHEIGHNLQR-SWWTMPGFTEVTNNVMCLMNYELVFGFASLQPSLKSLTSVKSAAGSGTSASSDGANGELDTEVAEALSYLKRGDAYTNW--SPNIGLQYFIHLISHFGLGLISNAWVNYNQFP-----VKPRGLDNWTLILSKEAGHSLVGLHEFWGLPTGQTTAAQLSKLPCFLPDDWITQQVTDR 728
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BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Match: A0A1S3I0H4 (TRPM8 channel-associated factor 2-like OS=Lingula unguis OX=7574 GN=LOC106159184 PE=4 SV=1)

HSP 1 Score: 237.269 bits (604), Expect = 7.743e-63
Identity = 147/489 (30.06%), Postives = 234/489 (47.85%), Query Frame = 2 
Query: 1331 PCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQ----WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVN-----------IFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGN------------YDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEE---KYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKST 2707
            P    PA   + R+ + + G+  +      +  KLP I +FP DF S P L+ V L +  +    R+  GYY+PAG+ +K  + +  G     W I +G H D L   +  W R+PD+      L     + SP+GG+L+  +   NA +++ + NVV  PFF++     V DW+  +R   GLWA++AG  +VF   S  +R+ D     +++  WD  V   +   G D    +  + V D   S GY H+GYP+ T+ D  V+           +F  + +K  G+WG+ HE+GHN Q    WT S + E TNNIF L+             T E + GN             +++   L     L+ WK+  +  L +Y Q+A+ FG+  F   F+ Y N  + + +S+++   K D+W    S I   NL P+ D W IP+   +R  L+ F  FLP+D    + ++R + +L  YP   R  +
Sbjct:  252 PSPKSPANTSAFRASVRVLGMLYRMTP-PQAFCKLPGIGVFPGDFSSKPPLQTVRLNLTTK-HRQRLSTGYYVPAGQPVKVTVTSDQGTDLSGWKICIGAHDDSLVNVKEPWRRWPDVAVLE-ELKATTALSSPYGGLLFFDSPERNAELTVIVCNVVEAPFFDLTKPEIVEDWSR-RRNAPGLWAELAGRHIVFTVPSTSVREIDDP--TTILALWDSAVAAQHDLRGTDRNLQKRERVVADEQPSAGYMHAGYPIVTHLD-VVDPNFQYNGSDNFVFSESGMKSYGNWGLFHEIGHNMQR-KAWTFSGMGEVTNNIFTLY-------------TYEAVTGNDAWNNPTMKKFRAEKLPRLLQSQPSLSDWKKDPFFALCVYSQLAHEFGWRSFKTVFRLYENSVKKEEESNQDDGAKIDMWFGRFSEIVRHNLSPMCDFWGIPLSTGVRNNLTLFPAFLPNDEITAAGQARVDQVLPNYPGIVRSPS 719
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: si:ch211-210b2.3 (si:ch211-210b2.3 [Source:ZFIN;Acc:ZDB-GENE-131122-13])

HSP 1 Score: 102.064 bits (253), Expect = 1.058e-21
Identity = 84/366 (22.95%), Postives = 153/366 (41.80%), Query Frame = 2 
Query: 1529 IPIGYYLPAGETLKYKIQAST--GQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENA--SISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKEL-LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            I  G YL  G      + A      W + +GC +D LG       R P ++       +   +++ +GG+++L+   +     + + +   +  P++    E++V++W    R     WA++  E+++   +S+ +RQ D                +   F        R  + V D+  S G+ H+GYP+         + +    ++ G WG  HELGHNQQ +        +E T N++ ++   +   +    + + +  +  +   +SY  GG  L  W  S +  L  Y+Q+ + FG+  F K F  Y     +  D++  K +L+A   S + N NL P F  W  PI       LS  
Sbjct:  543 ISTGLYLSPGMRTFVAVPAEIMDKGWQLQIGCQTDHLGHA-DVLRRAPVVHERFALDKDMLQVWNLWGGLIYLIAPPKCKLDGVEVIVQTAIKAPYYKS-GETSVANWMNEIRNAPAPWAELEFENIIITLQSEVIRQLDRP--------------DEVAFP-------RKERFVADVQISHGFMHAGYPIMILSCSAPELVNPESARKFGIWGAIHELGHNQQRWAWEFPPNTTECTCNLWSVYVHEEVLGVNRASAHENMSPERRWGRAQSYAMGGRQLDQW--SMWTALETYMQLQDRFGWDAFKKVFTAYHTINNVPGDNN-GKMNLYAETFSKVVNMNLAPFFKAWGWPIQPSTEDALSSL 882
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000051129.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:5658439:5662219:-1 gene:ENSAMXG00000036822.1 transcript:ENSAMXT00000051129.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 8.389e-17
Identity = 55/203 (27.09%), Postives = 92/203 (45.32%), Query Frame = 2 
Query: 2024 RPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELL-DGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPD 2629
            R  + V D+    G+ HSGYP+  +     ++ +     +   WG  HELGHNQQ          +E T N++ ++       +    +  ++      + IK Y++GG +L  W  + +  L  Y+Q+   FG+  F K F  Y +   +  D ++ K +L+A   S + N+NL P F  W  PI     + L    C LP+
Sbjct:   16 RKERFVADVQILAGFMHSGYPIMMHTVSAPDLVNPYVSGKSDFWGPVHELGHNQQHSDWEFPPYTTECTCNLWSVYVHEVVLGVKKADAHGQMTPQRRQNRIKKYIEGGRNLKDW--TVWTALETYMQLQEEFGWDAFKKVFAAYHDMTGVPQD-NKGKMNLYAETFSKVVNRNLTPFFKAWGWPIQPSTEEQL----CSLPE 211
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000976.1 (pep scaffold:Pmarinus_7.0:GL479898:35358:38300:-1 gene:ENSPMAG00000000885.1 transcript:ENSPMAT00000000976.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 127.102 bits (318), Expect = 4.343e-30
Identity = 92/373 (24.66%), Postives = 168/373 (45.04%), Query Frame = 2 
Query: 1484 EQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISV--GCHSDILGEKRSEWYRYPDIYTNSVPLS----EEGT--IFSPFGGVLWLV--NSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD-EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWN 2569
            ++V ++V  +   T +  G Y P  + +   + +     GI +  GCH+D L + ++   R+P++ T S+P+     + G   + S +GG+L+L+         I + +      P+F  L E+++  W E +R +   W+++A + ++    S+  R       + LM  WDR+       A       RP + V+D   S G+ H+GYP+  +      + +   ++ +G WG  HELGHN+Q          +EATNN+F ++   +   +    +  +L     +  ++ ++D G  LA W  + +  L  Y+Q+   FG+  F + F  Y         + E K   WA   S    +NL P F  W 
Sbjct:  511 QEVTIDVSSKEGLTWVSTGLYAPPAQRVLLDLPSLALGRGIQIQLGCHTDQLYDSKTM-KRHPEV-TRSMPVVRGEMDRGAMEVASSWGGLLYLLVPEGVSLGKIRVRVRGAARAPYFK-LGETSLQHWQEFERHYPAPWSELACDSLILTVPSEAARGLADP--ERLMRLWDRMTGAIAYLAAEPHPSARPERIVVDEQISHGWMHAGYPIMVHRASIPKLLNEQEMRAEGMWGPLHELGHNRQRPAWNFPPHTTEATNNLFAVYVHEEVLGVARARAHPDLRPAERERRLRDHVDAGCPLAAW--TVFTCLETYLQLQEAFGWDPFVRLFGDY-QRAASTPSTMEAKMSEWAERFSRCVGRNLAPFFSAWG 875
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Match: si:ch211-210b2.3 (TRPM8 channel-associated factor homolog [Source:NCBI gene;Acc:101159605])

HSP 1 Score: 102.064 bits (253), Expect = 1.191e-21
Identity = 84/363 (23.14%), Postives = 159/363 (43.80%), Query Frame = 2 
Query: 1538 GYYLPAGETLKYKIQASTGQ--WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNEN--ASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKEL-LDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKF 2611
            G YL  G      I A   Q  W I +GC +D L  +  E  R P ++      SE   +++ +GG+++LV   +     + + +   V  P++     +A + W+   R     WA++  ++++    S+ +R  +    + L + W+++++     A    +  R  + V D+  S G+ H+GYP+         + + +++K  G WG  HELGHNQQ          +E T N++ ++   +   +    +   + L+      ++Y+  G +L  W+   ++ L  Y+Q+ + FG+  F K F  YL   +   D +  K +L+    S     +L   F  W  PI     + LS  
Sbjct:  551 GLYLSPGMKTYISIPAQMVQKGWQIQIGCQTDQLNAE--ELKRPPRVHEQFAVTSEMMQVWNLWGGLIYLVAPPQADVHGVEVIVQMAVPAPYYKSGVTTAEA-WSL-LRTAPSPWAELEFDNIILTVPSEAVRTLE--RPEELAQLWNKIMKAIADLAAKPEKFPRKERFVADVQISHGWMHAGYPIMGQKSAVNELVNVDHMKSCGLWGPIHELGHNQQRGCWEFPPNTTECTCNLWSVYVHEEVLGIDRAKAHPNMSLENRKSRARNYVTQGRNLNSWE--MWVALETYMQLQDKFGWDAFKKVFAAYLQMSQFPGD-NPGKMNLYTETFSQTVGMDLTAFFKAWGWPIQASTEQKLSNL 904
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000011630.1 (SMESG000011630.1)

HSP 1 Score: 1911.35 bits (4950), Expect = 0.000e+0
Identity = 920/924 (99.57%), Postives = 921/924 (99.68%), Query Frame = 2 
Query:    2 MFYRSILIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK 2773
            MFYRS LIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQ STG+WGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAV DWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK
Sbjct:    1 MFYRSTLIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQTSTGKWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVLDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK 924
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000011622.1 (SMESG000011622.1)

HSP 1 Score: 712.22 bits (1837), Expect = 0.000e+0
Identity = 364/910 (40.00%), Postives = 530/910 (58.24%), Query Frame = 2 
Query:   62 AQENILLKKPAYANDYKEYIKNSNDGDKTTGMW-LRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGV-IQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLME-SWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYD---EIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKKK 2773
             QENILL KP   ++  E  KN NDG+     +    K V + VFDL+ VY V+K+I+ N K +  +  + YVG E   C  H+QI+ YK+C++ V +     I VNC  SG  G++IA+V G F +          ++EA+G+LI       +P I S        N F   + +R N+  + V  YS     +NE C+PIIW      TF  AC   + + +   FGK  +F   ++  D     ++   W+S      N++ S+   ++ + R  +KDG I+D        +++ +E+K +   G+IS+  DH  +    ++   S  + +N+FN+     +  +      T  + D+ ++ L ++  L+++  N++YL++ G+ L+ +M  +P K + N+K+  +    +KKY+ L++ ICPCK DPAT+ +DR ++ IFG+  KSQ L +SK+K PCIDLFP DF + PK E V   +  E A T+ PIGYYL  G TL YK+    G+W +S+GCH+D L + R EWYRYP+I+ N + +  EG+ FSPFGG LWL N+  N SI + ++N+V TPFFN+ D++AV DW E QR + GLWAQIAG++MV C  S  +R   G YLK LM  +WD +V+ +     ++W+  RP  TVLDIMTS GY HSGYP+S YDDWF  IF+ + I++KGSWGMCHE+GHN QE   WT    +E TNN+FCLFN  K WKLPYYGS +  L  +YD   +IK YLD  A+  +W    +  L IY QMANHFGF FF + F YY ++  L+  +D +K + W NVTS I  QNL+PIF  W  PI  E+   +   +C  P+DF+ + S  R + +  KY  C   S ++ DF+ E+L    R NFIK K
Sbjct:   17 GQENILLHKPVKVSEDTEKSKNLNDGNNNENCFNFDRKTVKWAVFDLEKVYQVQKLILWNTKVKSNISISFYVGTEFMPCKFHKQIQQYKLCRNDVTLSKQAKIEVNCQISGATGQFIAMVSGSFESNDQTNSFTICQVEAFGKLISTNKAKTRPEISSTPWPPLPPNYFEKIQRIRLNVTSVIVPSYSNAITFLNENCQPIIWTKDIQSTFGVACSKPDGKARLTVFGKNNFFKETLSSKDSELFASNLKRWMSPNLTYSNFIESKTLNSVEEFRKQVKDGSIIDLDVWNPMKEDIKKEVKKMWLNGQISINIDHTFWNEKSKEARESYLEFLNVFNVDFTPEFANWDKPTLVTFTEKDYNDDLLGVEEVLKRMTYNHEYLIKKGKDLIKTMKTIPNKFVSNSKIRPLLLLLVKKYNELLNAICPCKFDPATNSNDRLLLEIFGILFKSQALVNSKFKFPCIDLFPGDFVTPPKKENVTFVIQSETANTKNPIGYYLEPGSTLMYKVDEMNGRWSMSIGCHTDTLNDNRPEWYRYPNIHVNDIIIENEGSAFSPFGGTLWLQNNKANESIKLTITNIVPTPFFNVRDKNAVKDW-EKQRNNPGLWAQIAGDNMVICVESRMIRNLSGTYLKDLMRNNWDLLVKMDLSLKSVNWKSQRPEITVLDIMTSAGYGHSGYPISVYDDWFEGIFNMSLIEKKGSWGMCHEIGHNMQEGQ-WTFHGTTEVTNNLFCLFNYNKVWKLPYYGSEELKLYRDYDRIKDIKKYLDENANFDIWTSEPFHALLIYAQMANHFGFEFFKEVFAYYSDN-NLEPKTDSDKMNTWMNVTSRIVGQNLLPIFYFWGFPIDSEIEVSMKSLRCLFPEDFYREISEIRTKVVEAKYKSCDFNSKYFSDFSEENLRFDIRTNFIKTK 923
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000011627.1 (SMESG000011627.1)

HSP 1 Score: 692.96 bits (1787), Expect = 0.000e+0
Identity = 349/931 (37.49%), Postives = 531/931 (57.04%), Query Frame = 2 
Query:    2 MFYRSILIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTTGMW-LRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQL----VQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLME-SWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNY---DEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIK 2767
            M    IL ++  + I K    +ENI+L+KP   ++++   K  NDGDK    +  +SK+V + VFDL+  + V+K+I+ N K +     + YVG     C  H+QI  +++C + +I +   I +NC  S   G+Y A+V      E    +L   EIEA+G++I +     +P+I S++    +     N F   +++R N+  + V  YS     +NE C+PIIW      TF  AC   + + +   FGK  +F   ++  D     ++   W+S     P ++ S+   ++ + R  +KDG I+D        +++ +E+K +  +G+IS+  DH  +    ++   S  + +N+F++   +T+     S   T  + D+ ++ L ++  L+++  N++YL++ G+ L+ +M  +P K + N+K+  +    +KKY  L++ ICPCK DPA + +DR ++ IFG+  KSQ L +SK+K PCIDLFP DF + PK E V   +  E A T+ PIGYYL  G TL YK+    G+W +S+GCH+D L + R EWYRYP+I+ N + +  EG+ FSPFGG LWL N+  N SI + ++N+V TPFFN+ D++AV DW E QR + GLWAQIAG++MV C  S  +R   G YLK LM  +WD +V+ +     ++W+  RP   VLDIMT +GY HSGYP+S YDDWF  IF+ + I+  GSWGMCHE+GHN Q    WT     E TNN+FCLFN  K WK  Y    + +   NY    ++K YLD  A   +W    +  L IY QMANHFGFGFF + F YY +   L   ++ +K   W NVTS I  QNL+PIF  W  PI  E+   L  F CF P D+++  S  R + +  +Y  C +K+ +Y+D +  +L +  R NFI+
Sbjct:    1 MILIGILFLSWSVQISKICYGRENIILRKPVTVSEFQVKSKYLNDGDKKNYCFTFKSKSVKWAVFDLEKTFQVQKIILWNVKVKMNSLISFYVGTNFSPCKFHKQISQFQLCNTALINSQEKIEINCQSSQETGQYFALVADSLQNEDSSIKLTLCEIEAFGRVISS----ERPSIHSEIFSIDLPPIPPNYFEKIQKIRLNVSSVIVPSYSNAITFLNENCQPIIWTKDIQSTFGVACSKPDGKARLTVFGKNNFFKETLSSKDSELFASNLKRWMSPNLTYPTFIESKTLNSVEEFRKQVKDGSIIDLDVWNPMKEDIKKEVKKMWLKGQISINIDHTFWNEKSKEARESYLEFLNVFHVDFTSTFVNRKKSIRVTFTEKDYNDDLLGVEEVLKRMTYNHEYLIKKGKDLIKTMKTIPNKFVSNSKIRSLLFLLVKKYSELLNAICPCKFDPAINSNDRLLLEIFGILFKSQALVNSKFKFPCIDLFPGDFVTPPKKENVTFVIQSETANTKNPIGYYLEPGSTLMYKVDEMNGRWSMSIGCHTDTLNDNRPEWYRYPNIHVNDIMIENEGSAFSPFGGTLWLQNNKANESIKLTITNIVPTPFFNVRDKNAVKDW-EKQRNNPGLWAQIAGDNMVICVESRMIRNLSGTYLKDLMRNNWDLLVKMDLSLKSVNWKSQRPQLIVLDIMTYLGYGHSGYPISVYDDWFEGIFNMSLIERNGSWGMCHEIGHNMQNLR-WTFKGTVEVTNNLFCLFNYNKIWKQAYNEYNESIFFQNYHKLKKVKKYLDENAKFDIWTSEPFHALLIYAQMANHFGFGFFKEVFAYY-SANNLNPKTNSDKMKTWMNVTSRIVGQNLLPIFYFWGFPIDREIGNILESFPCFFPYDYYVNISTIRIKIVETRYKSCQKKAKYYKDISEGTLREEKRENFIQ 924
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000042174.1 (SMESG000042174.1)

HSP 1 Score: 682.945 bits (1761), Expect = 0.000e+0
Identity = 351/923 (38.03%), Postives = 543/923 (58.83%), Query Frame = 2 
Query:   14 SILIIALQIFILKALA-AQENILL-KKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMES-WDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLP-DDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKK 2770
            +I I+ L IF   +L+ + +NILL KK   A+D +++  N NDG+  T +   S N   I FDL   Y + K+I+ NG YR       Y+G+E + CH    I  Y  C   ++QN++   + C G    GRY+ ++KG       +E L   +IE YG+     P   +P + S  +   +++ F +A  +RKN+P   +  YS   + +N  CEPII+D+K +L F  AC  ++ +G+ + F K  Y   + +DA + + RT+ ++WL+ GN +P  + S   K +SD    +K G ++ F     +PD+++   K+LL  G +S+V +   +++   K   S  +I+N+FN+    ++ +  S     + DS F+E+ + L+  + +++ N+DYL+     +   +      +++N+K+ +     +KKY+ L+ +ICPC    ATD +DR +I   G   K+Q LA+S +K PC DLFP DF ++P    V L + G    T  PIGYYL AG TL+Y +  S+G W ISVGCH+D L +   EW RYP I    +P+S++G I+S FGGVLWL N+   + I+I LSNVV+ PFFN+ D +A S WN+ +R   G+W+QIAG+ +V CE S RL+ FDGQY+  LM + WD VVR   V    +W+  RP   VLD+M S G+ HSGYP+  Y +WF +IF+S+ I+  GSWGMCHE+GHN Q+   WT    +E TNN+ CLF   K +KLP YGS  + +  +  +I +YL+GGA+ + W+   +L L IY QM+ + G+GFF   F++Y  + ++   +D +K   + N++S I+ QNL+ +FD W  PI + +R+ LSK  CF P DDF +  S  R+ +I  KYP+C+ KS+FY+D++  S   G RPNFI++
Sbjct:    3 NIQILCLVIFSSVSLSMSNKNILLNKKILAASDSRDHSTNINDGNVKTCVRFESNNKKMIAFDLGQTYMINKIIVRNGDYRATEETNFYIGNEFQACHFQSLINKYGKCDP-LVQNNSTNELTCKGPSNVGRYLVLIKGNPFDYDPIERLYLCDIEVYGEESTNVPVPTRPVVDSVSLVPITKDYFKIAPIIRKNVPTAPIPPYSSAVIYLNRNCEPIIYDMK-SLPFGVAC--ESGKGRMVAFAKSAYLRNMNSDATQHQFRTNLLSWLTFGNPSPPTIISSQVKKMSDFYTLIKPGTVVYFDVWSSHPDDILNTWKALLLNGTVSMVVEITFWVSNTVKARNSYLQILNIFNVDFRNSFTSSSSVVNTEMPDSMFSEDLIGLEDLVHRMLLNHDYLISKAPLVAGLLPIFSSSMLDNSKMPEYLITIIKKYEKLLKWICPCDVQKATDPNDRKLIRFLGEIMKNQVLAYSNFKAPCGDLFPGDFVASPPKVIVKLNLIGVTPSTENPIGYYLEAGSTLEYNVIGSSGSWAISVGCHTDNLPDSLPEWARYPSINIYRIPISDKGHIYSGFGGVLWLYNNALGSKITIELSNVVVAPFFNLRDSNAASKWND-RRNSPGIWSQIAGDSIVICEESRRLKDFDGQYMVDLMRNIWDTVVRMEMVLTATNWKTERPQIVVLDVMISAGFGHSGYPIELYQEWFESIFNSSAIRATGSWGMCHEIGHNMQKPK-WTFQGTTEVTNNLLCLFVFEKFFKLPRYGSDIDHIRNDKSKITAYLEGGAEFSKWRSDPWLALLIYSQMSQYLGWGFFKDVFEFYETN-KISPITDSQKMITFMNISSIISQQNLISMFDFWGFPIDESLRQQLSKLPCFFPADDFLVSLSLIRKNYISNKYPECNSKSSFYKDYDSSSFINGMRPNFIQE 918
[Close]
BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Match: SMESG000042174.1 (SMESG000042174.1)

HSP 1 Score: 682.559 bits (1760), Expect = 0.000e+0
Identity = 351/923 (38.03%), Postives = 543/923 (58.83%), Query Frame = 2 
Query:   14 SILIIALQIFILKALA-AQENILL-KKPAYANDYKEYIKNSNDGDKTTGMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICHLHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVEELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPVMKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEWYFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDGDILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDKIMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYLLENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPATDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLEVFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSEWYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTPFFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLKSLMES-WDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYDDWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLFNTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYVQMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMPIFDLWNIPIGDEMRKYLSKFQCFLP-DDFFLKSSRSREEFILKKYPDCHRKSTFYEDFNPESLTQGHRPNFIKK 2770
            +I I+ L IF   +L+ + +NILL KK   A+D +++  N NDG+  T +   S N   I FDL   Y + K+I+ NG YR       Y+G+E + CH    I  Y  C   ++QN++   + C G    GRY+ ++KG       +E L   +IE YG+     P   +P + S  +   +++ F +A  +RKN+P   +  YS   + +N  CEPII+D+K +L F  AC  ++ +G+ + F K  Y   + +DA + + RT+ ++WL+ GN +P  + S   K +SD    +K G ++ F     +PD+++   K+LL  G +S+V +   +++   K   S  +I+N+FN+    ++ +  S     + DS F+E+ + L+  + +++ N+DYL+     +   +      +++N+K+ +     +KKY+ L+ +ICPC    ATD +DR +I   G   K+Q LA+S +K PC DLFP DF ++P    V L + G    T  PIGYYL AG TL+Y +  S+G W ISVGCH+D L +   EW RYP I    +P+S++G I+S FGGVLWL N+   + I+I LSNVV+ PFFN+ D +A S WN+ +R   G+W+QIAG+ +V CE S RL+ FDGQY+  LM + WD VVR   V    +W+  RP   VLD+M S G+ HSGYP+  Y +WF +IF+S+ I+  GSWGMCHE+GHN Q+   WT    +E TNN+ CLF   K +KLP YGS  + +  +  +I +YL+GGA+ + W+   +L L IY QM+ + G+GFF   F++Y  + ++   +D +K   + N++S I+ QNL+ +FD W  PI + +R+ LSK  CF P DDF +  S  R+ +I  KYP+C+ KS+FY+D++  S   G RPNFI++
Sbjct:    6 NIQILCLVIFSSVSLSMSNKNILLNKKILAASDSRDHSTNINDGNVKTCVRFESNNKKMIAFDLGQTYMINKIIVRNGDYRATEETNFYIGNEFQACHFQSLINKYGKCDP-LVQNNSTNELTCKGPSNVGRYLVLIKGNPFDYDPIERLYLCDIEVYGEESTNVPVPTRPVVDSVSLVPITKDYFKIAPIIRKNVPTAPIPPYSSAVIYLNRNCEPIIYDMK-SLPFGVAC--ESGKGRMVAFAKSAYLRNMNSDATQHQFRTNLLSWLTFGNPSPPTIISSQVKKMSDFYTLIKPGTVVYFDVWSSHPDDILNTWKALLLNGTVSMVVEITFWVSNTVKARNSYLQILNIFNVDFRNSFTSSSSVVNTEMPDSMFSEDLIGLEDLVHRMLLNHDYLISKAPLVAGLLPIFSSSMLDNSKMPEYLITIIKKYEKLLKWICPCDVQKATDPNDRKLIRFLGEIMKNQVLAYSNFKAPCGDLFPGDFVASPPKVIVKLNLIGVTPSTENPIGYYLEAGSTLEYNVIGSSGSWAISVGCHTDNLPDSLPEWARYPSINIYRIPISDKGHIYSGFGGVLWLYNNALGSKITIELSNVVVAPFFNLRDSNAASKWND-RRNSPGIWSQIAGDSIVICEESRRLKDFDGQYMVDLMRNIWDTVVRMEMVLTATNWKTERPQIVVLDVMISAGFGHSGYPIELYQEWFESIFNSSAIRATGSWGMCHEIGHNMQKPK-WTFQGTTEVTNNLLCLFVFEKFFKLPRYGSDIDHIRNDKSKITAYLEGGAEFSKWRSDPWLALLIYSQMSQYLGWGFFKDVFEFYETN-KISPITDSQKMITFMNISSIISQQNLISMFDFWGFPIDESLRQQLSKLPCFFPADDFLVSLSLIRKNYISNKYPECNSKSSFYKDYDSSSFINGMRPNFIQE 921
The following BLAST results are available for this feature:
BLAST of Peptidase M60 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
TCAF14.936e-3524.65TRPM8 channel associated factor 1 [Source:HGNC Sym... [more]
TCAF15.952e-3524.65TRPM8 channel associated factor 1 [Source:HGNC Sym... [more]
TCAF2C6.873e-3023.71TRPM8 channel associated factor 2C [Source:HGNC Sy... [more]
TCAF21.252e-2923.71TRPM8 channel associated factor 2 [Source:HGNC Sym... [more]
TCAF21.252e-2923.71TRPM8 channel associated factor 2 [Source:HGNC Sym... [more]
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
si:ch211-210b2.45.344e-3126.93si:ch211-210b2.4 [Source:ZFIN;Acc:ZDB-GENE-131122-... [more]
si:ch211-210b2.25.442e-3026.90si:ch211-210b2.2 [Source:ZFIN;Acc:ZDB-GENE-131118-... [more]
zgc:1621931.499e-2825.73zgc:162193 [Source:NCBI gene;Acc:323315][more]
zgc:1621931.499e-2825.73zgc:162193 [Source:NCBI gene;Acc:323315][more]
zgc:1621931.499e-2825.73zgc:162193 [Source:NCBI gene;Acc:323315][more]
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000045101.12.080e-3328.30TRPM8 channel-associated factor 2 [Source:NCBI gen... [more]
ENSXETT00000002244.16.462e-3225.15TRPM8 channel-associated factor homolog [Source:NC... [more]
ENSXETT00000045059.16.161e-3126.85TRPM8 channel-associated factor 2 [Source:NCBI gen... [more]
suox2.896e-3025.75sulfite oxidase [Source:Xenbase;Acc:XB-GENE-985202... [more]
ENSXETT00000045084.13.862e-3026.58TRPM8 channel-associated factor 2 [Source:NCBI gen... [more]
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Tcaf12.795e-3324.07TRPM8 channel-associated factor 1 [Source:MGI Symb... [more]
Tcaf12.795e-3324.07TRPM8 channel-associated factor 1 [Source:MGI Symb... [more]
Tcaf12.795e-3324.07TRPM8 channel-associated factor 1 [Source:MGI Symb... [more]
Tcaf34.271e-3026.36TRPM8 channel-associated factor 3 [Source:MGI Symb... [more]
Tcaf26.007e-2924.24TRPM8 channel-associated factor 2 [Source:MGI Symb... [more]
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BLAST of Peptidase M60 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5R8R3|TCAF1_PONAB8.523e-3524.88TRPM8 channel-associated factor 1 OS=Pongo abelii ... [more]
sp|A5PJN5|TCAF1_BOVIN1.450e-3424.88TRPM8 channel-associated factor 1 OS=Bos taurus OX... [more]
sp|Q9Y4C2|TCAF1_HUMAN2.858e-3424.65TRPM8 channel-associated factor 1 OS=Homo sapiens ... [more]
sp|Q8BNE1|TCAF1_MOUSE2.015e-3224.07TRPM8 channel-associated factor 1 OS=Mus musculus ... [more]
sp|Q6P6V7|TCAF3_RAT1.302e-2925.19TRPM8 channel-associated factor 3 OS=Rattus norveg... [more]
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BLAST of Peptidase M60 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A1S6KMG00.000e+099.57Peptidase M60 domain-containing protein OS=Schmidt... [more]
A0A1S6KMG40.000e+038.72Peptidase M60 domain-containing protein OS=Schmidt... [more]
V4A0M81.218e-6733.06Peptidase M60 domain-containing protein OS=Lottia ... [more]
A0A448WAZ01.275e-6326.06Peptidase M60 domain-containing protein OS=Protopo... [more]
A0A1S3I0H47.743e-6330.06TRPM8 channel-associated factor 2-like OS=Lingula ... [more]
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
si:ch211-210b2.31.058e-2122.95si:ch211-210b2.3 [Source:ZFIN;Acc:ZDB-GENE-131122-... [more]
ENSAMXT00000051129.18.389e-1727.09pep primary_assembly:Astyanax_mexicanus-2.0:1:5658... [more]
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
ENSPMAT00000000976.14.343e-3024.66pep scaffold:Pmarinus_7.0:GL479898:35358:38300:-1 ... [more]
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Peptidase M60 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
si:ch211-210b2.31.191e-2123.14TRPM8 channel-associated factor homolog [Source:NC... [more]
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BLAST of Peptidase M60 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000011630.10.000e+099.57SMESG000011630.1[more]
SMESG000011622.10.000e+040.00SMESG000011622.1[more]
SMESG000011627.10.000e+037.49SMESG000011627.1[more]
SMESG000042174.10.000e+038.03SMESG000042174.1[more]
SMESG000042174.10.000e+038.03SMESG000042174.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035615 ID=SMED30035615|Name=Peptidase M60 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2834bp
AATGTTTTATCGCTCAATTTTGATTATCGCGTTGCAGATTTTTATTTTGA
AAGCATTAGCCGCTCAAGAAAATATTCTTCTTAAAAAGCCGGCATATGCC
AATGACTACAAAGAATATATAAAGAACAGTAATGACGGCGACAAAACTAC
TGGAATGTGGCTGAGATCGAAAAACGTTATGTACATCGTGTTTGATCTTC
AGAGTGTTTATAACGTTGAAAAGGTTATCATAACGAATGGAAAATATCGA
GGGGAAGTTCCATTTACAATTTATGTGGGAGATGAAATGAGAATTTGTCA
TTTGCATAGACAGATAAAGAATTATAAAGTCTGTAAAAGTGGGGTCATTC
AAAACTCAAATGATATTTCAGTGAACTGCGCTGGATCCGGAGTCAAAGGA
CGATATATTGCGATTGTTAAAGGAGAGTTTTTGACTGAGAAACTCGTTGA
AGAGTTAAATTTTTATGAAATAGAGGCATATGGGCAATTGATTGGAGCAG
GGCCACAGTTTGCTAAACCAACAATTCCAAGCCAGTTGGTTCAGAAGGCA
TCAAGAAACGATTTCCCTCTTGCCAGGGAGTTGCGCAAAAATATTCCAGT
CATGAAAGTCGATGGCTACTCAATGGGATTTGTAAAAATAAATGAAAAAT
GTGAACCTATAATTTGGGACGTAAAATGGAATTTGACTTTTGCATTTGCT
TGCTATACAGACAACAAACAAGGTAAAGCCCTCTTTTTCGGAAAAGAATG
GTATTTCTGGTACATAATGAATGACGCTGACAAAACTGAAATCCGTACAA
GTTTCGTCAATTGGTTGTCCTCTGGTAACAAAAATCCAAATTATGTCAAT
TCTGAGAATTTTAAAACAATTTCTGACGTTCGTGGAGCTTTAAAGGATGG
CGACATTTTGGATTTCCATACAACCGTGGATTATCCCGATGAAGTTATTG
AAGAAATAAAGTCTTTACTGACACGCGGAAAGATTTCTTTGGTGTTTGAT
CATGACAGTTTTATTGCTGTTGACGAGAAAGTTACTAGGTCGAATGATAA
AATAATGAATATGTTCAATATCGCGTCTGACACGACGTACTTTACATTTG
GTTCTTCAGGGGAGTATACGATCAAAGATAGCGATTTCACGGAAGAGTTT
TTAGATTTAAAAGTGCGCCTTCGTAAACTTGTTGACAATTATGACTACTT
GTTAGAAAATGGACAATTTTTGTTAAATTCTATGAATAAAATGCCACCTA
AAATTATAGAAAATGCAAAGCTAGATGATGTTTCAAAAGATTTTTTAAAG
AAATATGATTATCTCATAAGTTATATTTGTCCTTGTAAAGATGATCCAGC
AACAGATGTTTCGGATAGGAGTATAATCTCTATTTTTGGATTATTTGCAA
AGAGCCAAGGTTTAGCACACTCAAAATATAAATTACCTTGCATAGATTTA
TTTCCCATGGATTTTAAATCAGCACCAAAATTGGAACAAGTAGTTTTGGA
GGTCTTTGGTGAAATAGCTTACACTAGAATCCCAATAGGATATTATCTTC
CAGCTGGGGAAACTTTGAAATACAAGATCCAAGCATCAACAGGACAGTGG
GGAATTAGTGTAGGATGTCATTCTGATATTCTTGGCGAAAAAAGATCGGA
ATGGTATCGATATCCAGATATTTATACAAATAGTGTACCATTATCTGAGG
AAGGAACTATATTTTCACCGTTCGGTGGCGTTTTATGGTTAGTTAATTCG
AATGAGAATGCTTCAATAAGTATCCATTTATCAAATGTGGTTTTAACTCC
ATTCTTTAATATTCTTGATGAATCTGCGGTCTCAGACTGGAATGAAAATC
AGAGGAAACATCAAGGCCTTTGGGCTCAAATAGCTGGTGAAGATATGGTA
TTTTGTGAAAGAAGCGATAGACTTAGACAATTTGATGGTCAGTATTTGAA
AAGCTTAATGGAGAGTTGGGATAGAGTTGTAAGAAATAATTATGTATTTG
CAGGATTGGACTGGAGAAAGTATAGACCATCCCAGACGGTTCTTGACATT
ATGACTTCTGTTGGTTATGCTCATTCAGGATATCCAGTCTCTACTTATGA
TGACTGGTTTGTGAATATATTTGATTCAAATTACATAAAGGAGAAAGGTA
GCTGGGGAATGTGCCATGAATTAGGACATAATCAGCAAGAATTCCATTTA
TGGACGATGTCAACTGTCAGTGAAGCGACTAACAATATATTCTGCCTTTT
TAATACTGCTAAAGAATGGAAACTTCCTTATTACGGTTCAACAAAAGAAT
TACTTGACGGAAATTATGATGAAATAAAGAGTTATTTAGATGGAGGGGCT
GATTTAGCCGTATGGAAAGAAAGTGCTTATCTAGAGTTGGCGATTTACGT
TCAAATGGCAAATCATTTCGGATTTGGATTTTTTAACAAGGCATTCAAGT
ATTATTTAAATCATCCAGAACTTAAAGCTGACAGTGATGAAGAAAAGTAC
GATTTGTGGGCAAATGTAACCAGCACGATAACGAATCAAAATCTCATGCC
CATATTTGATTTATGGAATATCCCAATTGGGGATGAAATGAGAAAATATC
TCTCGAAATTTCAATGTTTCTTACCCGATGATTTCTTTCTCAAATCAAGT
CGATCTCGTGAAGAATTTATCCTGAAAAAGTACCCAGATTGCCATAGGAA
ATCAACATTTTATGAAGATTTCAATCCAGAAAGTTTAACACAGGGTCACC
GTCCCAATTTTATCAAAAAGAAACTGTAAACAATTTACTAAAATATAATC
AACTGTTTATTATAAAATAATATGGAATTTGAAA
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protein sequence of SMED30035615-orf-1

>SMED30035615-orf-1 ID=SMED30035615-orf-1|Name=SMED30035615-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=926bp
MFYRSILIIALQIFILKALAAQENILLKKPAYANDYKEYIKNSNDGDKTT
GMWLRSKNVMYIVFDLQSVYNVEKVIITNGKYRGEVPFTIYVGDEMRICH
LHRQIKNYKVCKSGVIQNSNDISVNCAGSGVKGRYIAIVKGEFLTEKLVE
ELNFYEIEAYGQLIGAGPQFAKPTIPSQLVQKASRNDFPLARELRKNIPV
MKVDGYSMGFVKINEKCEPIIWDVKWNLTFAFACYTDNKQGKALFFGKEW
YFWYIMNDADKTEIRTSFVNWLSSGNKNPNYVNSENFKTISDVRGALKDG
DILDFHTTVDYPDEVIEEIKSLLTRGKISLVFDHDSFIAVDEKVTRSNDK
IMNMFNIASDTTYFTFGSSGEYTIKDSDFTEEFLDLKVRLRKLVDNYDYL
LENGQFLLNSMNKMPPKIIENAKLDDVSKDFLKKYDYLISYICPCKDDPA
TDVSDRSIISIFGLFAKSQGLAHSKYKLPCIDLFPMDFKSAPKLEQVVLE
VFGEIAYTRIPIGYYLPAGETLKYKIQASTGQWGISVGCHSDILGEKRSE
WYRYPDIYTNSVPLSEEGTIFSPFGGVLWLVNSNENASISIHLSNVVLTP
FFNILDESAVSDWNENQRKHQGLWAQIAGEDMVFCERSDRLRQFDGQYLK
SLMESWDRVVRNNYVFAGLDWRKYRPSQTVLDIMTSVGYAHSGYPVSTYD
DWFVNIFDSNYIKEKGSWGMCHELGHNQQEFHLWTMSTVSEATNNIFCLF
NTAKEWKLPYYGSTKELLDGNYDEIKSYLDGGADLAVWKESAYLELAIYV
QMANHFGFGFFNKAFKYYLNHPELKADSDEEKYDLWANVTSTITNQNLMP
IFDLWNIPIGDEMRKYLSKFQCFLPDDFFLKSSRSREEFILKKYPDCHRK
STFYEDFNPESLTQGHRPNFIKKKL*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000420parapharyngeal region
Vocabulary: INTERPRO
TermDefinition
IPR042279Pep_M60_3
IPR035423M60-like_N
IPR031161Peptidase_M60_dom
IPR008979Galactose-bd-like_sf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
Vocabulary: cellular component
TermDefinition
GO:0005575cellular_component
Vocabulary: biological process
TermDefinition
GO:0008150biological_process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR031161Peptidase family M60 domainSMARTSM01276M60_like_2coord: 507..807
e-value: 6.5E-44
score: 161.9
IPR031161Peptidase family M60 domainPFAMPF13402Peptidase_M60coord: 604..855
e-value: 6.2E-41
score: 140.7
IPR031161Peptidase family M60 domainPROSITEPS51723PEPTIDASE_M60coord: 507..807
score: 51.523
NoneNo IPR availableGENE3DG3DSA:1.10.1740.210coord: 604..728
e-value: 2.5E-8
score: 36.3
NoneNo IPR availablePANTHERPTHR15730:SF5SI:CH211-210B2.2-RELATEDcoord: 475..867
NoneNo IPR availablePANTHERPTHR15730EXPERIMENTAL AUTOIMMUNE PROSTATITIS ANTIGEN 2-RELATEDcoord: 475..867
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..21
score: 0.782
IPR008979Galactose-binding-like domain superfamilyGENE3DG3DSA:2.60.120.260coord: 17..161
e-value: 3.3E-10
score: 42.0
IPR008979Galactose-binding-like domain superfamilySUPERFAMILYSSF49785Galactose-binding domain-likecoord: 23..162
IPR042279Peptidase M60, enhancin-like domain 3GENE3DG3DSA:1.10.390.30coord: 730..886
e-value: 8.2E-19
score: 70.1
IPR035423M60-like domain, N-terminalPFAMPF17291M60-like_Ncoord: 511..586
e-value: 8.3E-6
score: 25.6