Cathepsin L2

Overview


Name	Cathepsin L2
Smed ID	SMED30035609
Length (bp)	1185

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Cathepsin L2 (SMED30035609) t-SNE clustered cells

Violin plots show distribution of expression levels for Cathepsin L2 (SMED30035609) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cathepsin L2 (SMED30035609) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cathepsin L2 (SMED30035609) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035609

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30035609	h1SMcG0007332	Contig139	GPL15192	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30035609	h1SMcG0012211	Contig139	GPL15192	PMID:23079596 Forsthoefel et al., 2012
Smed sexual biotype	SMED30035609	h1SMcG0007332	Contig35082	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035609	h1SMcG0007332	Contig35082	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035609	h1SMcG0007332	Contig47680	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035609	h1SMcG0007332	Contig47680	newmark_ests	PMID:29674431 Fincher et al., 2018
gut	SMED30035609	h1SMcG0007332	dd_Smed_v4_267_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30035609	h1SMcG0007332	dd_Smed_v4_267_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30035609	h1SMcG0007332	dd_Smed_v4_267_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30035609	h1SMcG0007332	dd_Smed_v6_267_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
intestinal phagocyte	SMED30035609	h1SMcG0007332	dd_Smed_v6_267_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
gut	SMED30035609	h1SMcG0007332	dd_Smed_v4_267_0_1	dd_Smed_v4	PMID:30962434 Cote et al., 2019

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSV (cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538])

HSP 1 Score: 348.206 bits (892), Expect = 3.277e-118
Identity = 176/338 (52.07%), Postives = 218/338 (64.50%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M   ++++ F + I +  P F  N  L+  W  +K   +R Y    E  RR +WE+N++ I  HN EY  GKH + + +N + D+TNEEF+ + +G    +   KG  F  P  +  LP +VDWR KGYVTPVKNQ+QCGSCWAFS TG+LEGQ FRKTG LVS SEQ LVDCS   GN+GC GG M  AF Y+ +  GL+SE  YPY A D  CKY     V   +GFT +  G E  L  AVATVGP+SVA+DA H SFQ YK GIY EP CS   LDHGVL VGYG E    N   YWLVKNSWG  WG +GY+K++KD+NN CGI+T+AS+P V
Sbjct:    1 MNLSLVLAAFCLGIASAVPKFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

[Close]

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M   ++++ F + I +  P F  N  L+  W  +K   +R Y    E  RR +WE+N++ I  HN EY  GKH + + +N + D+TNEEF+ + +G    +   KG  F  P  +  LP +VDWR KGYVTPVKNQ+QCGSCWAFS TG+LEGQ FRKTG LVS SEQ LVDCS   GN+GC GG M  AF Y+ +  GL+SE  YPY A D  CKY     V   +GFT +  G E  L  AVATVGP+SVA+DA H SFQ YK GIY EP CS   LDHGVL VGYG E    N   YWLVKNSWG  WG +GY+K++KD+NN CGI+T+AS+P V
Sbjct:    1 MNLSLVLAAFCLGIASAVPKFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

[Close]

BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSL (cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537])

HSP 1 Score: 342.043 bits (876), Expect = 1.027e-115
Identity = 174/338 (51.48%), Postives = 216/338 (63.91%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M   ++++ F + I +   T + +  L   W  +K    R Y    E  RR +WE+N++ I  HN EY  GKH++ + +N + D+T+EEF+ + +     R   KG  F  P    A P +VDWR KGYVTPVKNQ QCGSCWAFS TG+LEGQ FRKTG L+S SEQ LVDCSG  GNEGC GGLMD AF Y+    GL+SE  YPY AT+  CKY+    V   +GF DI    E  L  AVATVGP+SVAIDA H SF  YK GIY EP CS + +DHGVL VGYG E    +   YWLVKNSWG  WG+ GY+KM+KDR N CGI+++AS+P V
Sbjct:    1 MNPTLILAAFCLGIAS--ATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

[Close]

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M   ++++ F + I +   T + +  L   W  +K    R Y    E  RR +WE+N++ I  HN EY  GKH++ + +N + D+T+EEF+ + +     R   KG  F  P    A P +VDWR KGYVTPVKNQ QCGSCWAFS TG+LEGQ FRKTG L+S SEQ LVDCSG  GNEGC GGLMD AF Y+    GL+SE  YPY AT+  CKY+    V   +GF DI    E  L  AVATVGP+SVAIDA H SF  YK GIY EP CS + +DHGVL VGYG E    +   YWLVKNSWG  WG+ GY+KM+KDR N CGI+++AS+P V
Sbjct:    1 MNPTLILAAFCLGIAS--ATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

[Close]

BLAST of Cathepsin L2 vs. Ensembl Human
Match: CTSK (cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536])

HSP 1 Score: 317.775 bits (813), Expect = 2.730e-106
Identity = 161/317 (50.79%), Postives = 206/317 (64.98%), Query Frame = 1

Query:  184 TFSLNSE--LNEDWELYKTQFKRQYE-PLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMK-YGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFP 1119
            +F+L  E  L+  WEL+K   ++QY   + EI+RR+IWE+NL+YI  HNLE  LG HTY L +N   D+T+EE   K  G K+    S        PE  G  P +VD+R KGYVTPVKNQ QCGSCWAFS+ G+LEGQ  +KTG L++ S Q LVDC     N+GCGGG M NAF Y+ K  G++SE  YPY   +  C Y+ +     C G+ +I  GNE  L  AVA VGPVSVAIDAS  SFQ Y  G+Y +  C+ D L+H VLAVGYG + G  +W++KNSWG +WG  GYI M++++NN CGI+  ASFP
Sbjct:   13 SFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFP 327

[Close]

BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 312.768 bits (800), Expect = 1.180e-104
Identity = 153/312 (49.04%), Postives = 204/312 (65.38%), Query Frame = 1

Query:  211 EDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKA-----KFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE-NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            E W+ YK  F ++Y    E T    + +N+ +I  HN ++ LG+ T+ +GLN  ADL   +++      +  G    ++S   S F+AP N+  +P  VDWR    VT VKNQ  CGSCWAFS TG+LEGQH RK G LVS SEQ LVDCS  YGN GC GGLMD AF YI   +G+++E  YPY   D KC +++  V     G+ D   G+E  L +AVAT GP+S+AIDA H SFQLYK G+Y + +CS ++LDHGVL VGYG++   G+YW+VKNSWG  WG  GYI+++++RNN CG++T AS+PLV
Sbjct:   30 EKWDDYKEDFDKEYSESEEQTYMEAFVKNMIHIENHNRDHRLGRKTFEMGLNHIADLPFSQYRKLNGYRRLFGDSRIKNS---SSFLAPFNV-QVPDEVDWRDTHLVTDVKNQGMCGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGDYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 337

[Close]

BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: cpl-1 (CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H9G333])

HSP 1 Score: 246.514 bits (628), Expect = 1.163e-80
Identity = 114/197 (57.87%), Postives = 144/197 (73.10%), Query Frame = 1

Query:  541 CGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE-NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            CGSCWAFS TG+LEGQH RK G LVS SEQ LVDCS  YGN GC GGLMD AF YI   +G+++E  YPY   D KC +++  V     G+ D   G+E  L +AVAT GP+S+AIDA H SFQLYK G+Y + +CS ++LDHGVL VGYG++   G+YW+VKNSWG  WG  GYI+++++RNN CG++T AS+PLV
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGDYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198

[Close]

Query:  541 CGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE-NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            CGSCWAFS TG+LEGQH RK G LVS SEQ LVDCS  YGN GC GGLMD AF YI   +G+++E  YPY   D KC +++  V     G+ D   G+E  L +AVAT GP+S+AIDA H SFQLYK G+Y + +CS ++LDHGVL VGYG++   G+YW+VKNSWG  WG  GYI+++++RNN CG++T AS+PLV
Sbjct:    2 CGSCWAFSATGALEGQHARKLGQLVSLSEQNLVDCSTKYGNHGCNGGLMDQAFEYIRDNHGVDTEESYPYKGRDMKCHFNKKTVGADDKGYVDTPEGDEEQLKIAVATQGPISIAIDAGHRSFQLYKKGVYYDEECSSEELDHGVLLVGYGTDPEHGDYWIVKNSWGAGWGEKGYIRIARNRNNHCGVATKASYPLV 198

[Close]

BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597500:1 gene:WBGene00007055.1 transcript:F41E6.6.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 185.652 bits (470), Expect = 8.441e-54
Identity = 111/306 (36.27%), Postives = 168/306 (54.90%), Query Frame = 1

Query:  235 QFKRQYEPLTEITRRI-IWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-----KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQ--CSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            + +++Y    E+ +R  ++++N + IR+   + + G   Y  G  +++D+T  EFK   L       +         +     N   LP + DWR KG VT VKNQ  CGSCWAFSTTG++EG  F     LVS SEQ+LVDC     ++GC GGL  NA+  I++  GLE E  YPY      C   R  +    +G  ++ H +E ++   + T GP+S+ ++A+  + Q Y+ G+ +  +  C P  L+HGVL VGYG +    YW+VKNSWG +WG +GY K+ + + N CG+   A+  LV
Sbjct:  180 RHEKKYTNKREVLKRFRVFKKNAKVIRELQ-KNEQGTAVY--GFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSM--DQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMATSALV 476

[Close]

BLAST of Cathepsin L2 vs. Ensembl Celegans
Match: tag-196 (pep chromosome:WBcel235:V:8594914:8597469:1 gene:WBGene00007055.1 transcript:F41E6.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-196)

HSP 1 Score: 185.652 bits (470), Expect = 8.441e-54
Identity = 111/306 (36.27%), Postives = 168/306 (54.90%), Query Frame = 1

Query:  235 QFKRQYEPLTEITRRI-IWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-----KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQ--CSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            + +++Y    E+ +R  ++++N + IR+   + + G   Y  G  +++D+T  EFK   L       +         +     N   LP + DWR KG VT VKNQ  CGSCWAFSTTG++EG  F     LVS SEQ+LVDC     ++GC GGL  NA+  I++  GLE E  YPY      C   R  +    +G  ++ H +E ++   + T GP+S+ ++A+  + Q Y+ G+ +  +  C P  L+HGVL VGYG +    YW+VKNSWG +WG +GY K+ + + N CG+   A+  LV
Sbjct:  180 RHEKKYTNKREVLKRFRVFKKNAKVIRELQ-KNEQGTAVY--GFTKFSDMTTMEFKKIMLPYQWEQPVYPMEQANFEKHDVTINEEDLPESFDWREKGAVTQVKNQGNCGSCWAFSTTGNVEGAWFIAKNKLVSLSEQELVDCDSM--DQGCNGGLPSNAYKEIIRMGGLEPEDAYPYDGRGETCHLVRKDIAVYINGSVELPH-DEVEMQKWLVTKGPISIGLNAN--TLQFYRHGVVHPFKIFCEPFMLNHGVLIVGYGKDGRKPYWIVKNSWGPNWGEAGYFKLYRGK-NVCGVQEMATSALV 476

[Close]

BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087592)

HSP 1 Score: 338.961 bits (868), Expect = 9.462e-115
Identity = 168/316 (53.16%), Postives = 218/316 (68.99%), Query Frame = 1

Query:  211 EDWELYKTQFKRQYEPLTEITRRI-IWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILT--------RSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGS-ENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            E+W  +K + ++ Y+  TE   R+ I+ +N   I +HN  +  GK ++ L +N+YADL + EF+    G   T          S KG  F++P ++  LP +VDWRTKG VT VK+Q  CGSCWAFS+TG+LEGQHFRK+G LVS SEQ LVDCS  YGN GC GGLMDNAF YI    G+++E+ YPY A D  C +++  V  T  GFTDI  G+E  +A AVATVGPVSVAIDASH SFQ Y  G+YNEPQC    LDHGVL VG+G+ E+G +YWLVKNSWG +WG  G+IKM +++ NQCGI++++S+PLV
Sbjct:   27 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341

[Close]

BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0087593)

HSP 1 Score: 339.732 bits (870), Expect = 1.081e-114
Identity = 168/316 (53.16%), Postives = 218/316 (68.99%), Query Frame = 1

Query:  211 EDWELYKTQFKRQYEPLTEITRRI-IWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILT--------RSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGS-ENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            E+W  +K + ++ Y+  TE   R+ I+ +N   I +HN  +  GK ++ L +N+YADL + EF+    G   T          S KG  F++P ++  LP +VDWRTKG VT VK+Q  CGSCWAFS+TG+LEGQHFRK+G LVS SEQ LVDCS  YGN GC GGLMDNAF YI    G+++E+ YPY A D  C +++  V  T  GFTDI  G+E  +A AVATVGPVSVAIDASH SFQ Y  G+YNEPQC    LDHGVL VG+G+ E+G +YWLVKNSWG +WG  G+IKM +++ NQCGI++++S+PLV
Sbjct:   57 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371

[Close]

BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0339955)

HSP 1 Score: 329.717 bits (844), Expect = 3.763e-111
Identity = 166/308 (53.90%), Postives = 215/308 (69.81%), Query Frame = 1

Query:  235 QFKRQYEPLTEITRRI-IWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKF------LGKILTRS--STKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGS-ENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            + ++ Y+  TE   R+ I+ +N   I +HN  +  GK ++ L +N+YADL + EF+         L K L  +  S KG  F++P ++  LP +VDWRTKG VT VK+Q  CGSCWAFS+TG+LEGQHFRK+G LVS SEQ LVDCS  YGN GC GGLMDNAF YI    G+++E+ YPY A D  C +++  V  T  GFTDI  G+E  +A AVATVGPVSVAIDASH SFQ Y  G+YNEPQC    LDHGVL VG+G+ E+G +YWLVKNSWG +WG  G+IKM +++ NQCGI++++S+PLV
Sbjct:   32 EHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 338

[Close]

BLAST of Cathepsin L2 vs. Ensembl Fly
Match: Cp1 (gene:FBgn0013770 transcript:FBtr0304021)

HSP 1 Score: 301.212 bits (770), Expect = 2.295e-101
Identity = 144/233 (61.80%), Postives = 177/233 (75.97%), Query Frame = 1

Query:  433 STKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGS-ENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            S KG  F++P ++  LP +VDWRTKG VT VK+Q  CGSCWAFS+TG+LEGQHFRK+G LVS SEQ LVDCS  YGN GC GGLMDNAF YI    G+++E+ YPY A D  C +++  V  T  GFTDI  G+E  +A AVATVGPVSVAIDASH SFQ Y  G+YNEPQC    LDHGVL VG+G+ E+G +YWLVKNSWG +WG  G+IKM +++ NQCGI++++S+PLV
Sbjct:   18 SFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 249

[Close]

BLAST of Cathepsin L2 vs. Ensembl Fly
Match: CG5367 (gene:FBgn0032228 transcript:FBtr0080055)

HSP 1 Score: 219.935 bits (559), Expect = 2.158e-68
Identity = 110/317 (34.70%), Postives = 190/317 (59.94%), Query Frame = 1

Query:  190 SLNSELNEDWELYKTQFKRQY-EPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKI---LTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            S ++    ++E +K    R+Y     E+     +E+N + I +HN  Y  G+ ++ L  N +AD++ + +   FL  +   +  S+   ++ +    M  +P ++DWR+KG++TP  NQ  CGSC+AFS   S+ GQ F++TG ++S S+QQ+VDCS ++GN+GC GG + N  +Y+    G+  ++DYPY A  GKC++     V   + +  +   +E  +  AV  +GPV+++I+AS  +FQLY  GIY++P CS   ++H ++ +G+G +    YW++KN WG +WG +GYI++ K   N CGI+  A++ +V
Sbjct:   27 SSSANCKSEFEKFKNNNNRKYLRTYDEMRSYKAFEENFKVIEEHNQNYKEGQTSFRLKPNIFADMSTDGYLKGFLRLLKSNIEDSADNMAEIVGSPLMANVPESLDWRSKGFITPPYNQLSCGSCYAFSIAESIMGQVFKRTGKILSLSKQQIVDCSVSHGNQGCVGGSLRNTLSYLQSTGGIMRDQDYPYVARKGKCQFVPDLSVVNVTSWAILPVRDEQAIQAAVTHIGPVAISINASPKTFQLYSDGIYDDPLCSSASVNHAMVVIGFGKD----YWILKNWWGQNWGENGYIRIRKGV-NMCGIANYAAYAIV 338

[Close]

BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsla (cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106])

HSP 1 Score: 358.607 bits (919), Expect = 2.271e-122
Identity = 180/336 (53.57%), Postives = 226/336 (67.26%), Query Frame = 1

Query:  139 VLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            V ++ F + + A     +L+ +LN+ W+ +K    ++Y    E  RRIIWE+NL+ I  HNLE+ +G HTY LG+N + D+T+EEF+    G K       +GS FM P N   +P  +DWR KGYVTPVK+Q +CGSCWAFSTTG+LEGQ FRKTG LVS SEQ LVDCS   GNEGC GGLMD AF Y+  + GL+SE  YPY  TD + C +D        +GF DI  G E  L  A+A VGPVSVAIDA H SFQ Y+ GIY E +CS ++LDHGVLAVGYG E    +G  YW+VKNSW  +WG  GYI M+KDR+N CGI+T+AS+PLV
Sbjct:    3 VFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEP-NFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337

[Close]

Query:  139 VLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            V ++ F + + A     +L+ +LN+ W+ +K    ++Y    E  RRIIWE+NL+ I  HNLE+ +G HTY LG+N + D+T+EEF+    G K       +GS FM P N   +P  +DWR KGYVTPVK+Q +CGSCWAFSTTG+LEGQ FRKTG LVS SEQ LVDCS   GNEGC GGLMD AF Y+  + GL+SE  YPY  TD + C +D        +GF DI  G E  L  A+A VGPVSVAIDA H SFQ Y+ GIY E +CS ++LDHGVLAVGYG E    +G  YW+VKNSW  +WG  GYI M+KDR+N CGI+T+AS+PLV
Sbjct:    3 VFLAAFTLCLSAVFAAPTLDQQLNDHWDQWKKWHSKKYHATEEGWRRIIWEKNLKKIEMHNLEHSMGIHTYRLGMNHFGDMTHEEFRQVMNGFKHKKDRRFRGSLFMEP-NFIEVPNKLDWREKGYVTPVKDQGECGSCWAFSTTGALEGQMFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDQNGLDSEESYPYLGTDDQPCHFDPKNSAANDTGFVDIPSGKERALMKAIAAVGPVSVAIDAGHESFQFYQSGIYYEKECSSEELDHGVLAVGYGFEGEDVDGKKYWIVKNSWSENWGDKGYIYMAKDRHNHCGIATAASYPLV 337

[Close]

BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Match: ctsl.1 (cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61])

HSP 1 Score: 358.221 bits (918), Expect = 2.313e-122
Identity = 175/313 (55.91%), Postives = 225/313 (71.88%), Query Frame = 1

Query:  211 EDWELY--KTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKA-KFLGKILTRSSTK---GSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ED E +  K +F + Y    E + R++ W  N + +  HN+  D G  +Y LG+  +AD++NEE++   F G + + ++TK   GS F        +P TVDWR KGYVT +K+Q+QCGSCWAFS TGSLEGQ FRKTG LVS SEQQLVDCSG+YGN GC GGLMD AF YI    GL++E  YPY A DG+C+++ S V  +C+G+ DI  G+ES L  AVAT+GP+SVAIDA H SFQLY  G+YNEP CS  +LDHGVLAVGYGS NG +YW+VKNSWG+ WG+ GYI MS++++NQCGI+T+AS+PLV
Sbjct:   22 EDMEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334

[Close]

Query:  211 EDWELY--KTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKA-KFLGKILTRSSTK---GSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ED E +  K +F + Y    E + R++ W  N + +  HN+  D G  +Y LG+  +AD++NEE++   F G + + ++TK   GS F        +P TVDWR KGYVT +K+Q+QCGSCWAFS TGSLEGQ FRKTG LVS SEQQLVDCSG+YGN GC GGLMD AF YI    GL++E  YPY A DG+C+++ S V  +C+G+ DI  G+ES L  AVAT+GP+SVAIDA H SFQLY  G+YNEP CS  +LDHGVLAVGYGS NG +YW+VKNSWG+ WG+ GYI MS++++NQCGI+T+AS+PLV
Sbjct:   22 EDMEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334

[Close]

Query:  211 EDWELY--KTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKA-KFLGKILTRSSTK---GSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ED E +  K +F + Y    E + R++ W  N + +  HN+  D G  +Y LG+  +AD++NEE++   F G + + ++TK   GS F        +P TVDWR KGYVT +K+Q+QCGSCWAFS TGSLEGQ FRKTG LVS SEQQLVDCSG+YGN GC GGLMD AF YI    GL++E  YPY A DG+C+++ S V  +C+G+ DI  G+ES L  AVAT+GP+SVAIDA H SFQLY  G+YNEP CS  +LDHGVLAVGYGS NG +YW+VKNSWG+ WG+ GYI MS++++NQCGI+T+AS+PLV
Sbjct:   22 EDMEFHAWKLKFGKSYRSAEEESHRQLTWLTNRKLVLVHNMMADQGLKSYRLGMTYFADMSNEEYRQLVFRGCLGSMNNTKARGGSTFFRLRKAAVVPDTVDWRDKGYVTDIKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGSYGNYGCDGGLMDQAFQYIEANKGLDTEDSYPYEAQDGECRFNPSTVGASCTGYVDIASGDESALQEAVATIGPISVAIDAGHSSFQLYSSGVYNEPDCSSSELDHGVLAVGYGSSNGDDYWIVKNSWGLDWGVQGYILMSRNKSNQCGIATAASYPLV 334

[Close]

BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 365.54 bits (937), Expect = 6.258e-125
Identity = 180/341 (52.79%), Postives = 232/341 (68.04%), Query Frame = 1

Query:  121 YKMKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG----SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            Y M  ++ I+   +      PT   +  L+  W L+K   K+ Y P  E  RR++WE+NL  I  HNLE+ LGKH++ LG+N++ D+TNEEF+ + +     +   +GS F+AP N  + P +VDWR KGYVTPVK+Q QCGSCWAFSTTG+LEGQH+R TG ++S SEQ LVDCS A GN+GC GGLMD AF Y+    G++SE  YPYTA D + C YD +      +GF D+  G+E DL  AVA+VGPVSVA+DA H SFQ YK GIY EP+CS + LDHGVL VGYG     E+G  YW+VKNSW   WG  GYI ++KDR+N CGI+T+AS+PLV
Sbjct:    6 YIMALYLGIAAICLTTVFAAPT--TDPALDNHWNLWKNWHKKSYAPKEEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFR-QLMNGYKNQKKIRGSTFLAPNNFES-PKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 342

[Close]

BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: fcrl2 (Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-5904272])

HSP 1 Score: 363.614 bits (932), Expect = 2.395e-124
Identity = 179/339 (52.80%), Postives = 231/339 (68.14%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG----SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M  ++ I+   +      PT   +  L+  W L+K   K+ Y P  E  RR++WE+NL  I  HNLE+ LGKH++ LG+N++ D+TNEEF+ + +     +   +GS F+AP N  + P +VDWR KGYVTPVK+Q QCGSCWAFSTTG+LEGQH+R TG ++S SEQ LVDCS A GN+GC GGLMD AF Y+    G++SE  YPYTA D + C YD +      +GF D+  G+E DL  AVA+VGPVSVA+DA H SFQ YK GIY EP+CS + LDHGVL VGYG     E+G  YW+VKNSW   WG  GYI ++KDR+N CGI+T+AS+PLV
Sbjct:    1 MALYLGIAAICLTTVFAAPT--TDPALDNHWNLWKNWHKKSYAPKEEGWRRVLWEKNLRMIEFHNLEHSLGKHSHSLGMNQFGDMTNEEFR-QLMNGYKNQKKIRGSTFLAPNNFES-PKSVDWRKKGYVTPVKDQGQCGSCWAFSTTGALEGQHYRNTGKMISLSEQNLVDCSRAQGNQGCNGGLMDQAFQYVKDNGGIDSEDSYPYTAKDDQECHYDPNYNSANDTGFVDVTSGSEKDLMNAVASVGPVSVAVDAGHQSFQFYKSGIYYEPECSSEDLDHGVLVVGYGFEGEDEDGKKYWIVKNSWSEKWGNDGYIYIAKDRHNHCGIATAASYPLV 335

[Close]

BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ano1 (anoctamin 1, calcium activated chloride channel [Source:Xenbase;Acc:XB-GENE-5967576])

HSP 1 Score: 323.939 bits (829), Expect = 1.178e-108
Identity = 155/338 (45.86%), Postives = 222/338 (65.68%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYE-PLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENM---GALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MK+ + ++  L AI   R    +N  L+  W L+K    + YE  + ++ RRI WE+NL  +  HNLEY +G HTY LG+N  AD+T+EE K+K  G IL   S + + F + +N    G +P ++DWR KG V+ VKNQ  CGSCWAFS  G+LEGQ   KTG LVS S Q LVDCS  YGN+GCGGG M  AF Y++   G++S+  YPY A D KC YD +    TC+ +T+I  G E +L  A+ ++GP+SVAID +  SF LY+ G+Y++P CS  +++HGVLAVGYG+ NG ++WL+KNSWG  +G  GY+++++++ N CG+++   +P +
Sbjct:    1 MKSLIFLATVLAAIVKAR----INPALDNHWLLWKNTHNKDYEDEIEDLQRRITWEKNLNLVNMHNLEYSMGMHTYELGMNHLADMTSEEIKSKLTGLILPPQSERQATFSSQKNSTFGGKVPDSIDWRDKGCVSDVKNQGGCGSCWAFSAVGALEGQLMLKTGKLVSLSPQNLVDCSSKYGNKGCGGGFMTQAFQYVIDNKGIDSDSYYPYHAMDEKCHYDPTGKASTCAKYTEIVPGTEDNLKQALGSIGPISVAIDGTRPSFFLYRSGVYSDPTCS-HEVNHGVLAVGYGNLNGQDFWLLKNSWGTKYGDQGYVRIARNKGNLCGVASYTCYPEI 333

[Close]

BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: harbi1 (harbinger transposase derived 1 [Source:Xenbase;Acc:XB-GENE-6077433])

HSP 1 Score: 304.294 bits (778), Expect = 4.470e-101
Identity = 149/326 (45.71%), Postives = 204/326 (62.58%), Query Frame = 1

Query:  178 RPTFSLNSELNEDWELYKTQFKRQYE-PLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGA--------LPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMK-YGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            R     N  L+ +WE++KT + + Y+  + E+ RR+IWE+NL  IR HNLE+  G HTY LG+N++ D+T+EE        +   +  K    M P N+ +        +P ++D+R KGYVTP+++Q +CGSCWAFST G+LEGQ  +KTG LV  S Q LVDC     N GCGGG M  AF Y+ K  G++SE  YPY   D KCKY+ S       GF ++K G+E+ L  AV  VGP+SV IDA   +F LYK GIY +  C  D ++H VLAVGYG +  G YW++KNSWG  WG  GYI M++++ N CGI+  AS+P++
Sbjct:   15 RADLYYNGTLDSEWEIWKTTYHKHYDNKIHELMRRLIWEKNLNIIRSHNLEFTQGLHTYELGMNKFGDMTSEEV-------VRMMTGLKVHTGMGPTNLTSDEDEASQRIPNSIDYRKKGYVTPIRDQGECGSCWAFSTVGALEGQLMKKTGKLVGISPQNLVDC--VKDNFGCGGGYMTTAFKYVKKNKGIDSEEAYPYVGMDQKCKYNVSGRAAEIKGFKEVKKGSETALKKAVGLVGPISVGIDAGLDTFFLYKKGIYYDKSCDGDSINHAVLAVGYGKQKKGKYWIIKNSWGEDWGNKGYILMAREKGNACGIANLASYPVM 331

[Close]

BLAST of Cathepsin L2 vs. Ensembl Xenopus
Match: ctsk (cathepsin K (pycnodysostosis) [Source:NCBI gene;Acc:448216])

HSP 1 Score: 303.138 bits (775), Expect = 1.324e-100
Identity = 153/329 (46.50%), Postives = 205/329 (62.31%), Query Frame = 1

Query:  145 ISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYE-PLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
             S+   A+   +      S L+  WEL+K  + RQY   L EI RR IWE+NL  I QHN E+  G HTY L +N   D+T+EE   K +G  +  +    + ++ PE    +P  +D+R KGYVTPV NQ  CGSCWAFS+ G+LEGQ  +KTG LVS S Q LVDC     N GC GG M NAF Y+   G ++S+ +YPY   D  C Y+ +    TC G+ +I  G+E  L  AVA VGPVSV+IDAS  SFQ YK G+Y +  C+PD ++H VL VGYG+E G  +W++KNSWG  WG  GY+ +++D+ N CGI++ ASFP++
Sbjct:    4 FSLLSFALSLVKIGLCQESNLDSKWELWKKTYHRQYNGQLDEIRRRQIWEKNLNLISQHNKEFSQGLHTYDLAMNHLGDMTSEEVVQKMMGLKVPPNHRPNNTYI-PEWNSRIPEYIDYRKKGYVTPVHNQGICGSCWAFSSVGALEGQLMKKTGKLVSLSPQNLVDCDT--DNYGCEGGYMTNAFGYVRDNGGIDSDAEYPYVGQDEGCHYNPADKAATCKGYKEIPVGSEKALKRAVANVGPVSVSIDASLPSFQFYKKGVYYDSSCNPDAVNHAVLVVGYGNEKGIKHWIIKNSWGDWWGKKGYVLLARDKKNACGIASLASFPVM 329

[Close]

BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsl (cathepsin L [Source:MGI Symbol;Acc:MGI:88564])

HSP 1 Score: 330.102 bits (845), Expect = 2.894e-111
Identity = 169/319 (52.98%), Postives = 207/319 (64.89%), Query Frame = 1

Query:  184 TFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            T   +   + +W  +K+  +R Y    E  RR IWE+N+  I+ HN EY  G+H + + +N + D+TNEEF+ + +     +   KG  F  P  M  +P +VDWR KG VTPVKNQ QCGSCWAFS +G LEGQ F KTG L+S SEQ LVDCS A GN+GC GGLMD AF YI +  GL+SE  YPY A DG CKY     V   +GF DI    E  L  AVATVGP+SVA+DASH S Q Y  GIY EP CS   LDHGVL VGYG E    N   YWLVKNSWG  WG+ GYIK++KDR+N CG++T+AS+P+V
Sbjct:   18 TPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFR-QVVNGYRHQKHKKGRLFQEPL-MLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333

[Close]

Query:  184 TFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            T   +   + +W  +K+  +R Y    E  RR IWE+N+  I+ HN EY  G+H + + +N + D+TNEEF+ + +     +   KG  F  P  M  +P +VDWR KG VTPVKNQ QCGSCWAFS +G LEGQ F KTG L+S SEQ LVDCS A GN+GC GGLMD AF YI +  GL+SE  YPY A DG CKY     V   +GF DI    E  L  AVATVGP+SVA+DASH S Q Y  GIY EP CS   LDHGVL VGYG E    N   YWLVKNSWG  WG+ GYIK++KDR+N CG++T+AS+P+V
Sbjct:   18 TPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFR-QVVNGYRHQKHKKGRLFQEPL-MLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333

[Close]

BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctsll3 (cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917452])

HSP 1 Score: 320.472 bits (820), Expect = 1.792e-107
Identity = 163/335 (48.66%), Postives = 209/335 (62.39%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE-NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M    L++   + + +  P    N  L+  WE +KT+ K+ Y    E  +R +WE N + I  HN +Y  GKH + L +N + DLTN EF+    G    ++      F  P  +G +P +VDWR  GYVTPVK+Q  CGSCWAFS  GSLEGQ FRKTG LV  S Q LVDCS + GN+GC GGL D AF Y+    GL++   YPY A +G C+Y+      T +GF +++  +E  L  AVATVGP+SV ID  H SFQ YK G+Y EP CS   LDH VL VGYG E +G  YWLVKNSWG  WG++GYIKM+KDRNN CGI++ AS+P+V
Sbjct:    1 MTPVFLLATLCLGVVSAAPAH--NPSLDAVWEEWKTKHKKTYNMNDEGQKRAVWENNKKMIDLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQGQKTKMMMKVFQEPL-LGDVPKSVDWRDHGYVTPVKDQGSCGSCWAFSAVGSLEGQMFRKTGKLVPLSVQNLVDCSWSQGNQGCDGGLPDLAFQYVKDNGGLDTSVSYPYEALNGTCRYNPKNSAATVTGFVNVQ-SSEDALMKAVATVGPISVGIDTKHKSFQFYKEGMYYEPDCSSTVLDHAVLVVGYGEESDGRKYWLVKNSWGRDWGMNGYIKMAKDRNNNCGIASDASYPVV 331

[Close]

BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: BC051665 (cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:2682300])

HSP 1 Score: 312.383 bits (799), Expect = 2.008e-104
Identity = 160/335 (47.76%), Postives = 208/335 (62.09%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMK-YGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE-NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M    L++   + + +  P    +  L+  WE +KT+ ++ Y    E  +R +WE N++ I  HN +Y  GKH + L +N + DLTN EF+    G   +    + + F  P  +G +P +VDWR  GYVTPVK+Q  CGSCWAFS  GSLEGQ FRKTG LV  SEQ L+DCS +YGN GC GGLM+ AF Y+ +  GL++   Y Y A DG C+YD        +GF  +   +E  L  AVA+VGPVSV ID  H+SF+ Y+GG Y EP CS   LDH VL VGYG E +G  YWLVKNSWG  WG+ GYIKM+KDR+N CGI+T A +P V
Sbjct:    1 MTPVFLLATLCLGVVSAAPAH--DPSLDAVWEEWKTKHRKTYNMNEEAQKRAVWENNMKMIGLHNEDYLKGKHGFNLEMNAFGDLTNTEFRELMTG-FQSMGHKEMTIFQEPL-LGDVPKSVDWRDHGYVTPVKDQGHCGSCWAFSAVGSLEGQIFRKTGKLVPLSEQNLMDCSWSYGNVGCNGGLMELAFQYVKENRGLDTRESYAYEAWDGPCRYDPKYSAVNITGFVKVPL-SEDALMNAVASVGPVSVGIDTHHHSFRFYRGGTYYEPDCSSTNLDHAVLVVGYGEESDGRKYWLVKNSWGEDWGMDGYIKMAKDRDNNCGIATYAIYPTV 330

[Close]

BLAST of Cathepsin L2 vs. Ensembl Mouse
Match: Ctss (cathepsin S [Source:MGI Symbol;Acc:MGI:107341])

HSP 1 Score: 308.145 bits (788), Expect = 1.654e-102
Identity = 160/333 (48.05%), Postives = 216/333 (64.86%), Query Frame = 1

Query:  139 VLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEI-TRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSG--AYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ++ SV +  +Q R PT      L+  W+L+K   +++Y+   E   RR+IWE+NL++I  HNLEY +G HTY +G+N+  D+TNEE   +     + R S K   F +  N   LP TVDWR KG VT VK Q  CG+CWAFS  G+LEGQ   KTG L+S S Q LVDCS    YGN+GCGGG M  AF YI+  G +E++  YPY ATD KC Y+      TCS +  +  G+E  L  AVAT GPVSV IDASH SF  YK G+Y++P C+ + ++HGVL VGYG+ +G +YWLVKNSWG+++G  GYI+M+++  N CGI++  S+P +
Sbjct:   17 LVCSVAMEQLQ-RDPT------LDYHWDLWKKTHEKEYKDKNEEEVRRLIWEKNLKFIMIHNLEYSMGMHTYQVGMNDMGDMTNEEILCRMGALRIPRQSPKTVTFRSYSNR-TLPDTVDWREKGCVTEVKYQGSCGACWAFSAVGALEGQLKLKTGKLISLSAQNLVDCSNEEKYGNKGCGGGYMTEAFQYIIDNGGIEADASYPYKATDEKCHYNSKNRAATCSRYIQLPFGDEDALKEAVATKGPVSVGIDASHSSFFFYKSGVYDDPSCTGN-VNHGVLVVGYGTLDGKDYWLVKNSWGLNFGDQGYIRMARNNKNHCGIASYCSYPEI 340

[Close]

BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P25782|CYSP2_HOMAM (Digestive cysteine proteinase 2 OS=Homarus americanus OX=6706 GN=LCP2 PE=2 SV=1)

HSP 1 Score: 357.066 bits (915), Expect = 3.771e-121
Identity = 184/337 (54.60%), Postives = 231/337 (68.55%), Query Frame = 1

Query:  127 MKAFVLISVFL--VAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MK  VL   FL  VA+ A  P+          WE +K ++ RQY    E + RR+I+EQN +YI + N +Y+ G+ T+ L +N++ D+T EEF A   G I  RS+   S F   +  G   T VDWRTKG VTPVK+Q QCGSCWAFSTTGSLEGQHF KTGSL+S +EQQLVDCS  YG +GC GG M++AF+YI    G+++E  YPY A DG C++D + V  TCSG T+I  G+E+ L  AV  +GP+SV IDA+H SFQ Y  G+Y EP CSP  LDH VLAVGYGSE G ++WLVKNSW  SWG +GYIKMS++RNN CGI+T AS+PLV
Sbjct:    1 MKVAVL---FLCGVALAAASPS----------WEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYIEEFNKKYENGEVTFNLAMNKFGDMTLEEFNAVMKGNIPRRSAPV-SVFYPKKETGPQATEVDWRTKGAVTPVKDQGQCGSCWAFSTTGSLEGQHFLKTGSLISLAEQQLVDCSRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYEARDGSCRFDSNSVAATCSGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323

[Close]

BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|O60911|CATL2_HUMAN (Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2)

HSP 1 Score: 348.206 bits (892), Expect = 1.574e-117
Identity = 176/338 (52.07%), Postives = 218/338 (64.50%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M   ++++ F + I +  P F  N  L+  W  +K   +R Y    E  RR +WE+N++ I  HN EY  GKH + + +N + D+TNEEF+ + +G    +   KG  F  P  +  LP +VDWR KGYVTPVKNQ+QCGSCWAFS TG+LEGQ FRKTG LVS SEQ LVDCS   GN+GC GG M  AF Y+ +  GL+SE  YPY A D  CKY     V   +GFT +  G E  L  AVATVGP+SVA+DA H SFQ YK GIY EP CS   LDHGVL VGYG E    N   YWLVKNSWG  WG +GY+K++KD+NN CGI+T+AS+P V
Sbjct:    1 MNLSLVLAAFCLGIASAVPKFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

[Close]

BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q9GKL8|CATL1_CHLAE (Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CTSL PE=1 SV=1)

HSP 1 Score: 343.969 bits (881), Expect = 6.584e-116
Identity = 178/335 (53.13%), Postives = 214/335 (63.88%), Query Frame = 1

Query:  136 FVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            F+L ++ L    A   T + N  L   W  +K    R Y    E  RR +WE+N++ I  HN EY  GKH++ + +N + D+T+EEF+ + +     R   KG  F  P    A P +VDWR KGYVTPVKNQ QCGSCWAFS TG+LEGQ FRKTG LVS SEQ LVDCSG  GNEGC GGLMD AF Y+    GL+SE  YPY AT+  CKY+    V   +GF DI    E  L  AVATVGP+SVAIDA H SF  YK GIY EP CS + +DHGVL VGYG E    +   YWLVKNSWG  WG+ GYIKM+KDR N CGI+++AS+P V
Sbjct:    5 FILAALCLGIASA---TLTFNHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHSFTMAMNTFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVADNGGLDSEESYPYEATEESCKYNPEYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFMFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNSKYWLVKNSWGEEWGMGGYIKMAKDRRNHCGIASAASYPTV 333

[Close]

BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|P07711|CATL1_HUMAN (Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2)

HSP 1 Score: 342.043 bits (876), Expect = 4.934e-115
Identity = 174/338 (51.48%), Postives = 216/338 (63.91%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M   ++++ F + I +   T + +  L   W  +K    R Y    E  RR +WE+N++ I  HN EY  GKH++ + +N + D+T+EEF+ + +     R   KG  F  P    A P +VDWR KGYVTPVKNQ QCGSCWAFS TG+LEGQ FRKTG L+S SEQ LVDCSG  GNEGC GGLMD AF Y+    GL+SE  YPY AT+  CKY+    V   +GF DI    E  L  AVATVGP+SVAIDA H SF  YK GIY EP CS + +DHGVL VGYG E    +   YWLVKNSWG  WG+ GY+KM+KDR N CGI+++AS+P V
Sbjct:    1 MNPTLILAAFCLGIAS--ATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

[Close]

BLAST of Cathepsin L2 vs. UniProt/SwissProt
Match: sp|Q95029|CATL_DROME (Cathepsin L OS=Drosophila melanogaster OX=7227 GN=Cp1 PE=2 SV=2)

HSP 1 Score: 339.732 bits (870), Expect = 1.084e-113
Identity = 168/316 (53.16%), Postives = 218/316 (68.99%), Query Frame = 1

Query:  211 EDWELYKTQFKRQYEPLTEITRRI-IWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILT--------RSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGS-ENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            E+W  +K + ++ Y+  TE   R+ I+ +N   I +HN  +  GK ++ L +N+YADL + EF+    G   T          S KG  F++P ++  LP +VDWRTKG VT VK+Q  CGSCWAFS+TG+LEGQHFRK+G LVS SEQ LVDCS  YGN GC GGLMDNAF YI    G+++E+ YPY A D  C +++  V  T  GFTDI  G+E  +A AVATVGPVSVAIDASH SFQ Y  G+YNEPQC    LDHGVL VG+G+ E+G +YWLVKNSWG +WG  G+IKM +++ NQCGI++++S+PLV
Sbjct:   57 EEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHV-TLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDSCHFNKGTVGATDRGFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 371

[Close]

BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A2U8U447 (Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 511.916 bits (1317), Expect = 1.404e-179
Identity = 236/334 (70.66%), Postives = 283/334 (84.73%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MK  +L S+FLV IQA    F++NSELN++WE+YK +F ++YE L EI+RRIIWE NL++I+QHN+EYDLGKHTYYLGLNE+AD+T+EEFKAK+LG K + R+ T  S+F+ PEN+G LPT +DWRTKGYVTPVKNQ QCGSCWAFSTTGSLEGQHFRK+G LVSFSEQQLVDCS ++ N GC GGLMDNAF+YI K+G+E+E  YPY A DG C YD++K+VGTC+GF DIK GNE+DL  AVAT GP+SVAIDAS+ SFQ Y+GGIYNEP CS   LDHGVLA+GYGSEN  NYW+VKNSW ISWG+SGYI+MSKD+ NQCGI+T AS+PLV
Sbjct:    1 MKIILLTSIFLVTIQAVPHKFTINSELNDEWEVYKMKFSKKYETLNEISRRIIWENNLKFIQQHNVEYDLGKHTYYLGLNEFADMTHEEFKAKYLGLKPINRNFT-SSRFIIPENIGDLPTRIDWRTKGYVTPVKNQGQCGSCWAFSTTGSLEGQHFRKSGKLVSFSEQQLVDCSRSFDNLGCNGGLMDNAFSYIQKFGIENEISYPYVANDGVCAYDKTKIVGTCTGFVDIKTGNETDLMAAVATQGPISVAIDASNDSFQFYRGGIYNEPHCSSKDLDHGVLAIGYGSENNENYWIVKNSWDISWGMSGYIRMSKDKMNQCGIATMASYPLV 333

[Close]

BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A267H1I6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig013052g1 PE=3 SV=1)

HSP 1 Score: 422.935 bits (1086), Expect = 1.465e-144
Identity = 205/334 (61.38%), Postives = 250/334 (74.85%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MKA  LI++ LVA     P F+L  ELNE+WE YK+   + YE   E+ RR+IWEQNL++I++HNLEYD G H+Y LG+N++ DLT  EFKAK+L   +  +  +GS F+   N+G+LP  VDWRTKGYVT VK+Q+QCGSCWAFSTTGSLEGQHF+KTG+LVS SEQ LVDCSG +GN GC GGLMDN F YI    G+++E  YPY A D KC +  S V  T SGF DI   NES L  AVAT+GP+SVAIDA H SFQLYK G+Y+E  CS  QLDHGVLAVGYG+E G  YWLVKNSWG SWG+ GYI MS+++ NQCGI+++AS+PLV
Sbjct:    1 MKAAALIALCLVAAATAYPQFTL--ELNEEWEAYKSTHGKVYEADEELMRRLIWEQNLQHIQKHNLEYDRGVHSYTLGMNQFGDLTFTEFKAKYLSP-MPAAEPEGSVFLPASNVGSLPDEVDWRTKGYVTGVKDQKQCGSCWAFSTTGSLEGQHFKKTGNLVSLSEQNLVDCSGKFGNMGCNGGLMDNGFKYIKANKGIDTEACYPYKARDEKCSFKSSCVGATVSGFVDIPAKNESALQQAVATIGPISVAIDAGHSSFQLYKSGVYSERLCSETQLDHGVLAVGYGTEGGKAYWLVKNSWGTSWGMKGYIMMSRNKKNQCGIASAASYPLV 331

[Close]

BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A1I8GVB7 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=3 SV=1)

HSP 1 Score: 422.935 bits (1086), Expect = 1.689e-144
Identity = 205/334 (61.38%), Postives = 250/334 (74.85%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MKA  LI++ LVA     P F+L  ELNE+WE YK+   + YE   E+ RR+IWEQNL++I++HNLEYD G H+Y LG+N++ DLT  EFKAK+L   +  +  +GS F+   N+G+LP  VDWRTKGYVT VK+Q+QCGSCWAFSTTGSLEGQHF+KTG+LVS SEQ LVDCSG +GN GC GGLMDN F YI    G+++E  YPY A D KC +  S V  T SGF DI   NES L  AVAT+GP+SVAIDA H SFQLYK G+Y+E  CS  QLDHGVLAVGYG+E G  YWLVKNSWG SWG+ GYI MS+++ NQCGI+++AS+PLV
Sbjct:    1 MKAAALIALCLVAAATAYPQFTL--ELNEEWEAYKSTHGKVYEADEELMRRLIWEQNLQHIQKHNLEYDRGVHSYTLGMNQFGDLTFTEFKAKYLSP-MPAAEPEGSVFLPASNVGSLPDEVDWRTKGYVTGVKDQKQCGSCWAFSTTGSLEGQHFKKTGNLVSLSEQNLVDCSGKFGNMGCNGGLMDNGFKYIKANKGIDTEACYPYKARDEKCSFKSSCVGATVSGFVDIPAKNESALQHAVATIGPISVAIDAGHSSFQLYKSGVYSERLCSETQLDHGVLAVGYGTEGGKAYWLVKNSWGTSWGMKGYIMMSRNKKNQCGIASAASYPLV 331

[Close]

BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A0L8HPF9 (Uncharacterized protein OS=Octopus bimaculoides OX=37653 GN=OCBIM_22009826mg PE=3 SV=1)

HSP 1 Score: 406.757 bits (1044), Expect = 4.846e-138
Identity = 198/337 (58.75%), Postives = 246/337 (73.00%), Query Frame = 1

Query:  124 KMKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPL-TEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSST--KGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            KMK+ V + +F VA  A  P    ++ L++ W+ Y   F ++Y     E  RR+IWE+NL+Y+ QHNLE D+G HTY+LGLNEYADL N EF  + +  ++ R+ T  K     A +N+  LP TVDWRTKGYVT VKNQ QCGSCWAFSTTGSLEGQ F+KTG LVS SEQ LVDCSG++GN GC GGLMDNAF YI K+G++SE  YPY   D KC+Y +S VV T +G+ D+K  +E  L  AVA VGP+SVAIDA H SFQLYK G+Y E +CS   LDHGVLAVGYG++NG +YWLVKNSWG SWG+ GYIKM++++NN CGI+T AS+P V
Sbjct:    2 KMKSLVAVLLF-VACAASVPLS--DNFLDQSWQTYMKLFNKKYNTAENEFVRRVIWEKNLQYVNQHNLEADMGLHTYWLGLNEYADLENREFVQR-MNNLIPRNLTTYKPKLIFANDNIKDLPDTVDWRTKGYVTEVKNQAQCGSCWAFSTTGSLEGQIFKKTGKLVSLSEQNLVDCSGSFGNNGCEGGLMDNAFKYIKKFGIDSEASYPYEGRDAKCRYKKSDVVATDTGYVDVKSMSEDSLQSAVAKVGPISVAIDAGHLSFQLYKHGVYKESRCSATALDHGVLAVGYGTDNGQDYWLVKNSWGGSWGVKGYIKMARNQNNMCGIATQASYPTV 334

[Close]

BLAST of Cathepsin L2 vs. TrEMBL
Match: A0A0N9WMD3 (Cathepsin L OS=Cerebratulus lacteus OX=6221 PE=2 SV=1)

HSP 1 Score: 405.216 bits (1040), Expect = 1.542e-137
Identity = 195/334 (58.38%), Postives = 245/334 (73.35%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ++AFVL+    VA  A      L  +L+ +WE++K   K+ YE  TE  R+ ++  NL YI++HN E D+GKHT++LG+NEY+D T+ EF     G  +  + T GS ++   N+ A P TVDWR+KGYVTPVKNQ QCGSCWAFSTTGSLEGQH+RK   L S SEQQLVDCSGAYGN GC GGLMDNAF YI    GL++E+ YPY A + +C++ +S V  T +GF D++ G+E  L  AV+ VGPVSVAIDA H SFQ Y+ G+YNEP+CS   LDHGVL VGYGSENG +YWLVKNSWG SWG++GYIKMS++RNNQCGI+T AS+PLV
Sbjct:    2 IRAFVLLVALTVAFSA-----PLEQQLDSEWEMFKATHKKTYETKTETLRKAVFMNNLRYIQKHNAEADMGKHTFWLGVNEYSDWTSLEFAKYANGYRMALNRTSGSTYLPASNVKA-PDTVDWRSKGYVTPVKNQGQCGSCWAFSTTGSLEGQHYRKYQKLPSLSEQQLVDCSGAYGNNGCQGGLMDNAFKYIKANQGLDTEQCYPYEAQNDRCRFQKSCVAATVTGFVDVQRGSEDALKSAVSEVGPVSVAIDAGHPSFQGYRSGVYNEPRCSQTALDHGVLVVGYGSENGQDYWLVKNSWGPSWGINGYIKMSRNRNNQCGIATQASYPLV 329

[Close]

BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: si:dkey-26g8.5 (cathepsin L1-like [Source:NCBI gene;Acc:103028700])

HSP 1 Score: 353.599 bits (906), Expect = 1.488e-120
Identity = 173/319 (54.23%), Postives = 224/319 (70.22%), Query Frame = 1

Query:  190 SLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG----SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            SL+ +L++ W+L+K+   + Y    E  RR++WE+NL+ +  HNLE+ +GKHTY LG+N++AD+TNEEF+    G +      +KGS F+ P  +  +P  VDWR KGYVTPVK+Q +CGSCWAFS+TG+LEGQHFRKTG LVS SEQ LVDCS   GN+GC GG+M+ AF Y+    G++SE  YPYTA D + C+YD +      +GF DI  G E  L  AVA VGPVSVAIDA H SFQ Y+ GIY E  CS ++LDHGVL VGYG     E+G  YW+VKNSW   WG +GYI M+KDR N CGI+++AS+PL+
Sbjct:   21 SLDRQLDDHWKLWKSWHSKSYHEKEEGWRRLVWEKNLKKVELHNLEHSMGKHTYRLGMNQFADMTNEEFRQAMNGYRSNPNKKSKGSLFLEPSFL-EVPKQVDWREKGYVTPVKDQARCGSCWAFSSTGALEGQHFRKTGKLVSLSEQNLVDCSRPEGNQGCNGGIMEQAFQYVKDNGGIDSEESYPYTAKDDQPCRYDPNFNSANDTGFVDIPSGEEHALMKAVAAVGPVSVAIDAGHESFQFYQSGIYYEKACSSEELDHGVLVVGYGFEGADEDGKKYWIVKNSWSEKWGQNGYIYMAKDRKNHCGIASAASYPLM 338

[Close]

BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ctsl.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023607])

HSP 1 Score: 348.977 bits (894), Expect = 8.600e-119
Identity = 171/312 (54.81%), Postives = 216/312 (69.23%), Query Frame = 1

Query:  211 EDWELY--KTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKF---LGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYI-MKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ED E +  K +F + Y  + E + R++ W  N + +  HN+  D G  +Y LG+  +AD+ N+E++  F   LG      +   + F+       LP TVDWR KGYVT +K+Q+ CGSCWAFS TGSLEGQ FRKTG LVS SEQQLVDCSG YGN GCGGGLMD AF YI    G+++E  YPY A DG C++    V  TC+GF DI  G+E  L  AVAT+GP+SVAIDA H SFQLY+ GIYNEP CS  +LDHGVLAVGYG++NG +YWLVKNSWG+ WG  GYI+MS++ +NQCGI+T +S+PLV
Sbjct:   22 EDLEFHAWKLKFGKIYHSVEEESQRKLTWLTNRKLVLVHNMLADQGIKSYRLGMTFFADMDNKEYRKLFASCLGSFNRTKAHSATTFLRQTLRDPLPDTVDWRPKGYVTDIKDQKDCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNFGCGGGLMDQAFEYIKANKGIDTEDSYPYEAVDGDCRFKPDSVGATCTGFVDITSGDEKALQEAVATIGPISVAIDAGHSSFQLYESGIYNEPDCSSTELDHGVLAVGYGTDNGKDYWLVKNSWGLDWGNKGYIQMSRNEDNQCGIATMSSYPLV 333

[Close]

BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000042132.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 343.584 bits (880), Expect = 1.315e-116
Identity = 172/339 (50.74%), Postives = 219/339 (64.60%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWEL--YKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKG---SQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M+ F+ ++  +  + A   +        ED E   +K +  + Y P  E  R+I W  N + +  HN+  D G  TY LG+  +AD+ N+E++    G + + + TK    S F+       LP TVDWRT+GYVT VKNQ+ CGSCWAFS TG+LEGQ FRK G L+  SEQQLVDCS  YGN GC GG M+ AF Y+   G L++E  YPY A +G C+Y    V  TCSG+ DI  G+E  L  AVATVGPVSVAID  HYSFQLY+ G+Y+EP CS   L H VLAVGYGS+ G +YWLVKNSWG  WG  GYIKMS+++NNQCGI+T+AS+PLV
Sbjct:    1 MRVFLAVATLVAVVGAASISM-------EDLEFHAWKLKLGKVYNPAEESQRKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQMLQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332

[Close]

BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000048039.1 (cathepsin L1-like [Source:NCBI gene;Acc:103023924])

HSP 1 Score: 343.584 bits (880), Expect = 1.315e-116
Identity = 172/339 (50.74%), Postives = 219/339 (64.60%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWEL--YKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKG---SQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M+ F+ ++  +  + A   +        ED E   +K +  + Y P  E  R+I W  N + +  HN+  D G  TY LG+  +AD+ N+E++    G + + + TK    S F+       LP TVDWRT+GYVT VKNQ+ CGSCWAFS TG+LEGQ FRK G L+  SEQQLVDCS  YGN GC GG M+ AF Y+   G L++E  YPY A +G C+Y    V  TCSG+ DI  G+E  L  AVATVGPVSVAID  HYSFQLY+ G+Y+EP CS   L H VLAVGYGS+ G +YWLVKNSWG  WG  GYIKMS+++NNQCGI+T+AS+PLV
Sbjct:    1 MRVFLAVATLVAVVGAASISM-------EDLEFHAWKLKLGKVYNPAEESQRKITWLANRKLVLVHNMLADQGLKTYRLGMTHFADMDNQEYRQMLQGCLGSFNETKAPGASSFLRQAGGATLPNTVDWRTQGYVTEVKNQEMCGSCWAFSATGALEGQMFRKLGYLLPLSEQQLVDCSREYGNMGCSGGWMNQAFQYVKDNGGLDTEDSYPYEAMEGYCRYYPDAVGATCSGYVDISIGDEQALQEAVATVGPVSVAIDVGHYSFQLYQSGVYDEPDCSTSALGHAVLAVGYGSDYGQDYWLVKNSWGTYWGDQGYIKMSRNKNNQCGIATAASYPLV 332

[Close]

BLAST of Cathepsin L2 vs. Ensembl Cavefish
Match: ENSAMXT00000047972.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000030.1:138766:150097:-1 gene:ENSAMXG00000038942.1 transcript:ENSAMXT00000047972.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 338.191 bits (866), Expect = 1.614e-114
Identity = 168/312 (53.85%), Postives = 219/312 (70.19%), Query Frame = 1

Query:  211 EDWEL--YKTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFK---AKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ED E   +K +F + Y    E + R++IW  NL+ + +HN+  D G  ++ LG+N +AD+ N+EF+   ++ LG   T      ++F       A+P TVDWRT+GYVT VK+Q  CGSCWAFS+TG+LEGQ F+KTGSLVS SEQQLVDCS +YGN GC GGLM  AFNY+M   GL++E  YPY   D  C++++  V  TCSG+T I  G+E +L   V TVGPVSVA+DA   SFQLY+ GIY+E  CS  QL+HGVLAVGYGS+NG +YWLVKNSW  SWG +GYI+MS+++NNQCGI+T A +P V
Sbjct:   20 EDLEFQEWKLKFGKSYSSEAEESQRKMIWMTNLKLVLEHNMLADQGLKSHRLGMNHFADMENQEFRKMLSRCLGSFDTTKIHNATKFTGKAGGAAVPDTVDWRTQGYVTEVKSQGLCGSCWAFSSTGALEGQMFKKTGSLVSLSEQQLVDCSESYGNNGCNGGLMSYAFNYVMNNGGLDTEASYPYEGQDSVCRFNQYSVGATCSGYTFISSGSEEELKEVVGTVGPVSVAVDA-EVSFQLYQSGIYDESDCSSTQLNHGVLAVGYGSQNGKDYWLVKNSWSTSWGEAGYIRMSRNKNNQCGIATFALYPEV 330

[Close]

BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006499.1 (pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 gene:ENSPMAG00000005817.1 transcript:ENSPMAT00000006499.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 364.77 bits (935), Expect = 1.494e-125
Identity = 182/336 (54.17%), Postives = 228/336 (67.86%), Query Frame = 1

Query:  142 LISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG--KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDG-KCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG----SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            L+   L  + +  P    +  L+E+W  +K   ++ YEP  E  RR+IWE+NL  I+ HNLE+ LGKHT+ +G+N + D+TNEEF+ K  G   +     +KGS F+ P+N  A P TVDWR KG VT VK+Q +CGSCWAFSTTG+LEGQH RK G LVS SEQ LVDCS A GN+GCGGGLMD AF Y+    G++SE  YPYT TDG KC YD        +GF D+  G+E  L +AVA+VGPVSVAIDASH SFQ Y+ G+Y EP CS   LDHGVL VGYG     ENG  YW+VKNSW   WG  GY+ M++++ N CGI+T+AS+PLV
Sbjct:    7 LVPALLAVMASATPIH--DPMLDEEWGSWKGFHQKLYEPKQESWRRMIWEKNLNKIKIHNLEHSLGKHTWRMGMNHFGDMTNEEFRQKMNGYHGVQPHKVSKGSTFLVPQNYEA-PPTVDWRDKGLVTEVKDQGECGSCWAFSTTGALEGQHMRKVGQLVSLSEQNLVDCSRAEGNQGCGGGLMDQAFQYVKDNGGIDSEAAYPYTGTDGDKCHYDPKFNSANDTGFVDVTSGDEKALKIAVASVGPVSVAIDASHESFQFYQSGVYFEPDCSSQDLDHGVLVVGYGVKGTGENGKKYWIVKNSWSPKWGDEGYVLMARNKKNHCGIATAASYPLV 339

[Close]

BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011285.1 (pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gene:ENSPMAG00000010258.1 transcript:ENSPMAT00000011285.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 332.028 bits (850), Expect = 2.329e-113
Identity = 169/299 (56.52%), Postives = 209/299 (69.90%), Query Frame = 1

Query:  244 RQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG---KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG-SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            + Y+   E  RR+IWE+NL+ I  HNLE+ +GKHT+ +G+N + D+T EEF+   LG      T  +++G+ FMAP    A P +VDWR +GYVT VK+Q  CGSCWAFSTTGSLEGQH RKTG LVS SEQ LVDCS A GN GC GGLMD AF YI K  G++SE  YPYTA D  CKY+        +GF DI  GNE  L  AVA+VGPVS+ IDAS  SFQLY  GIY++  CS + LDHGVL VGYG  ++   +W+VKNSWG  WG  GYI M++D++N CGI+T+AS+PLV
Sbjct:    1 KTYDQNEEGWRRMIWEKNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTKEEFQHTMLGLRGSNDTSKASRGATFMAPAFFKA-PESVDWRKQGYVTDVKDQGDCGSCWAFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSAEGNNGCKGGLMDLAFTYIKKNGGIDSEASYPYTAKDENCKYNPKNKAAEDTGFVDIPSGNEEALKNAVASVGPVSIGIDASLESFQLYSSGIYSDSDCS-NNLDHGVLVVGYGVDDDERKFWIVKNSWGTKWGDHGYILMARDKDNLCGIATAASYPLV 297

[Close]

BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010475.1 (pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 gene:ENSPMAG00000009483.1 transcript:ENSPMAT00000010475.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 323.168 bits (827), Expect = 6.703e-110
Identity = 163/289 (56.40%), Postives = 201/289 (69.55%), Query Frame = 1

Query:  274 RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKIL---TRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG-SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            RRIIWE+NL+ I  HNLE+ +GKHT+ +G+N+++D+T EEF+   LG      T  + +G+ FMAP    A P +VDWR +GYVT +KNQ  CGSCW+FSTTGSLEGQH RKTG LVS SEQ LVDCS   GN GC GGLM NAFNYI K  G++SE  YPY      CKYD        +G+ +I  G+E  L  AVA+VGPVSVAIDAS  SFQ Y  GIY +  CS   +DH VL VGYG  E G  +WLVKNSWG++WG  GY++M++D NN CGI+T +S+PLV
Sbjct:    7 RRIIWEKNLKRISVHNLEHSMGKHTWRMGMNQFSDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFFEA-PESVDWRKQGYVTDIKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNHGCNGGLMINAFNYIKKNGGIDSEESYPYKGQVETCKYDPKNKAAEVTGYVEIPEGDEEALMNAVASVGPVSVAIDASLASFQSYGSGIYKDAMCS-HHIDHAVLVVGYGVDEMGQKFWLVKNSWGVTWGEQGYVRMARDDNNLCGIATMSSYPLV 293

[Close]

BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008535.1 (pep scaffold:Pmarinus_7.0:GL478103:36116:54424:1 gene:ENSPMAG00000007699.1 transcript:ENSPMAT00000008535.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 319.316 bits (817), Expect = 1.299e-107
Identity = 163/332 (49.10%), Postives = 218/332 (65.66%), Query Frame = 1

Query:  133 AFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKG---SQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATD-GKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG----SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGI 1098
             F  +   + A+   RP  +L+      WE +   FK+ Y     I RR+IWE+N+ ++ +HNLE+ LG H+Y LG+N  ADLT +EF+    G +  +R   +G   S F+APEN   +P ++DWR +G VTP+KNQ QCGSCWAFS+TG+LEGQ  R++G LV  SEQ L+DCS   G EGCGGG MD+AF Y++   G++SE DYPYTATD   C YD S++V   SGF DI  G+E DL  AVA+VGPVSVAIDA H SFQLY+ GIY EP+C+  +LDH VL VG+G     ENG  +W+VKN  G+  G   Y++++ D+   CG+
Sbjct:   12 VFACLVALVGALAVSRPDPALDGH----WEAWTVYFKKAYTQTDGIKRRLIWEENMRFVDRHNLEHSLGLHSYTLGMNHLADLTVDEFRKTMNGYRRGSRERHEGHHTSTFLAPENY-EVPQSMDWRDQGLVTPIKNQGQCGSCWAFSSTGALEGQWKRRSGELVPLSEQNLLDCSRPEGTEGCGGGWMDDAFQYVLDQGGIDSESDYPYTATDVDSCHYDPSRMVARISGFVDIHKGSEKDLITAVASVGPVSVAIDAGHQSFQLYESGIYYEPECNCTELDHAVLVVGFGVKGRGENGKKFWIVKNRRGLQCGGEIYLEVAVDKRCFCGL 338

[Close]

BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003800.1 (pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 gene:ENSPMAG00000003453.1 transcript:ENSPMAT00000003800.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 309.686 bits (792), Expect = 1.361e-104
Identity = 161/290 (55.52%), Postives = 198/290 (68.28%), Query Frame = 1

Query:  274 RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKIL---TRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYG-SENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            RR+IWEQNL+ I  HNLE+ +GKHT+ +G+N + D+T EEF+   LG      T  + +G+ FMAP    A P +VDWR +GYVT VKNQ  CGSCW+FSTTGSLEGQH RKTG LVS SEQ LVDCS   GN GC GGLM NAFNYI K  G++SE  YPY     + CKY+        +G+ +I  G+E  L  AVA+VGPVSVAIDAS  SF  Y  GIY +  CS   ++H VL VGYG  E G  +WLVKNSWG+ WG  GY++M++D NN CGI+ +AS+PLV
Sbjct:    8 RRMIWEQNLKKIAVHNLEHSMGKHTWRMGMNRFGDMTGEEFQQVMLGFRGWNGTSKAPRGATFMAPAFFEA-PESVDWRKQGYVTDVKNQGDCGSCWSFSTTGSLEGQHKRKTGVLVSLSEQNLVDCSSTEGNYGCNGGLMINAFNYIKKNGGIDSEESYPYKGQGVETCKYNPKNKAAEVTGYVEIPEGDEEALKNAVASVGPVSVAIDASLNSFLYYISGIYKDKLCS-HIINHAVLVVGYGVDEKGDKFWLVKNSWGVQWGEKGYVRMARDDNNLCGIAVTASYPLV 295

[Close]

BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO46465 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPY5])

HSP 1 Score: 379.407 bits (973), Expect = 2.607e-131
Identity = 192/336 (57.14%), Postives = 238/336 (70.83%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNED--WELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MKAF  ++  LVA+   +      SEL++D  W  +K    + Y    E  RR IW  NLE +++HN E     H+Y L +N +ADLT  EFK +F+G     +ST GS F+   N+  LP  VDWR KG+VT VKNQ QCGSCWAFS+TGSLEGQHFRKTG LVS SEQ LVDCS  YGN GC GGLMD AF YI    G+++E+ YPYTA DG+C +    V  T +G+TD++ G+E DL  AVATVGP+SVAIDA H SFQLYK G+Y+EP CS  QLDHGVLAVGYG+E+G +YWLVKNSWG  WG++GYIKMS++++NQCGI+T AS+PLV
Sbjct:    1 MKAF--LACLLVAVLIAQ----CFSELSQDRQWHAWKDFHGKTYTGEEEDLRRAIWNDNLEIVKKHNAE----NHSYKLDMNHFADLTVTEFKQRFMGYRAASNSTGGSTFLPLSNV-QLPAEVDWRDKGFVTAVKNQGQCGSCWAFSSTGSLEGQHFRKTGKLVSLSEQNLVDCSKKYGNNGCEGGLMDYAFKYIKNNDGIDTEQSYPYTARDGQCHFKPGSVGATVTGYTDVQRGSEGDLQSAVATVGPISVAIDAGHSSFQLYKTGVYSEPDCSSTQLDHGVLAVGYGAEDGKDYWLVKNSWGEGWGMNGYIKMSRNKDNQCGIATQASYPLV 325

[Close]

BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45953 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRH6])

HSP 1 Score: 351.288 bits (900), Expect = 3.684e-120
Identity = 178/337 (52.82%), Postives = 229/337 (67.95%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPL-TEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKG--SQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MK F+++ V + + +     F  +SE    W  +K+   + Y  +  E TR  IW+QNLE I++HN E     H+Y + +N   DLT +EF+  +LG     +STK   + +M P N+  +P++VDW  KGYVT VKNQ QCGSCWAFSTTGS+EGQHFRKTGSLVS SEQ L+DCSG+YGN GC GGLMDNAF YI    G+++E  YPY    G C +  S V    +G+ DI  G+E  L  AVATVGPVSVA+DAS +  Q Y  G+Y+ P CS  QLDHGVL +GYG+ NG +YWLVKNSWG SWG+ GYI MS+++NNQCGI++SAS+PLV
Sbjct:    1 MKVFLVLCVLVASSRGWSVRFGQDSE----WVAWKSYHGKSYSDVHEERTRMAIWQQNLEKIKRHNAE----DHSYKMAMNHLGDLTEDEFRYFYLGVRAHHNSTKRGWATYMPPSNV-KIPSSVDWSQKGYVTGVKNQGQCGSCWAFSTTGSVEGQHFRKTGSLVSLSEQNLIDCSGSYGNNGCQGGLMDNAFRYIESNGGIDTESSYPYLGQQGSCHFSSSHVGARVTGYQDIPQGSEQALQSAVATVGPVSVAVDASQW--QFYSSGVYDNPYCSSTQLDHGVLVIGYGNYNGQDYWLVKNSWGYSWGVEGYIMMSRNKNNQCGIASSASYPLV 326

[Close]

BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO36727 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SHX1])

HSP 1 Score: 341.273 bits (874), Expect = 2.706e-116
Identity = 170/338 (50.30%), Postives = 222/338 (65.68%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEI-TRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSS---TKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MK  V   +           F  + +  + W+L+ T   ++Y  +TE   R+ IW  NL+ I++HN E     H++ L +N   DLT +EF+  + G     S+    +GS F+AP ++  +P TVDWR +GYVTPVKNQ QCGSCWAFSTTGSLEGQ+F+KTG LVS SEQ LVDCS AYGN GC GGLMD AF YI + G +++E  YPY A + +C++ +S +    +GF D+ HG+E  L  A  TVGP+SVAIDA H SFQ Y  G+YN   CS   LDHGVL VGYG+  G +YWLVKNSWG  WG+ GYI MS+++NNQCG++T AS+PLV
Sbjct:    1 MKLLVAACLLFAVASGFVVKFDEDEQQWQAWKLFHT---KKYTTVTEEGARKAIWRDNLKKIQKHNAE----GHSFTLAMNHLGDLTQDEFRYFYTGMRSHYSNYTKKQGSAFLAPSHV-QVPDTVDWRKEGYVTPVKNQGQCGSCWAFSTTGSLEGQNFKKTGKLVSLSEQNLVDCSTAYGNNGCQGGLMDYAFKYIKENGGIDTEESYPYEARNDRCRFQKSNIGAVDTGFVDVTHGDEEALKTAAGTVGPISVAIDAGHMSFQFYHSGVYNNAGCSSTSLDHGVLVVGYGTYQGSDYWLVKNSWGERWGMEGYIMMSRNKNNQCGVATQASYPLV 330

[Close]

BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO45852 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL9])

HSP 1 Score: 340.887 bits (873), Expect = 4.373e-116
Identity = 166/334 (49.70%), Postives = 228/334 (68.26%), Query Frame = 1

Query:  139 VLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEIT-RRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTR---SSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
             +I   L+ I +      +    + +W+ +K+   ++Y    E T R  IW+ NL+ I  HN     GKH++ L +N   D+T+ E     LG  L +   S  KG+ F+ P N+  +  ++DWR+KGYVTPVKNQ QCGSCWAFSTTG+LEGQHFRKTG LVS SEQ LVDCSG YGN GC GGLMDNAF YI + G +++E+ YPY A DG C Y++S +    +GF DI  G+E+ L  A+A+VGP+S+AIDAS  +F  Y  G+Y++P CS  +LDHGVLAVGYG+++G +YWLVKNSWG SWG  GYIK++++ +++CG+++ AS+PLV
Sbjct:    3 AVIFAVLLCISSALAMPPMEPLQDPNWKAWKSFHGKEYPNKNEETMRNFIWQNNLKKIVTHNE----GKHSFKLAMNHLGDMTSLEISQTLLGLKLKKHAESQPKGATFLPPANVKVV-DSIDWRSKGYVTPVKNQGQCGSCWAFSTTGALEGQHFRKTGKLVSLSEQNLVDCSGKYGNNGCEGGLMDNAFQYIKENGGIDTEKSYPYLAKDGVCHYNKSAIGAKDTGFVDIPTGDENALQQALASVGPISIAIDASQSTFHFYHQGVYDDPDCSSTRLDHGVLAVGYGTDDGKDYWLVKNSWGPSWGEEGYIKIARNDHDKCGVASKASYPLV 331

[Close]

BLAST of Cathepsin L2 vs. Ensembl Nematostella
Match: EDO41322 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4P4])

HSP 1 Score: 221.476 bits (563), Expect = 4.634e-67
Identity = 121/315 (38.41%), Postives = 187/315 (59.37%), Query Frame = 1

Query:  202 ELNEDWELYKTQFKRQYEPLTEI-TRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPE--NMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKY-GLESERDY-PYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQC--SPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            +++  ++ Y  + K+ Y+   E  TRR  ++ NL +I   N  +      YYL +N   D +++E +    G+  T+    G  +  P+  ++  +P  ++W  +G VTPVK+Q  CGSCW+F TTG++EG  F KT  L   S+Q L+DCS   GN  C GG    ++ YIMK  G+ +E  Y PY   DG C    +++  T +G+ +I  G+ S L  A+A  GP+SV+IDASH S   Y  G+Y EP+C    + LDH VLAVGYG+ +G  YW++KNSW   WG++GY+ MS+ ++N CG++T+A++ L+
Sbjct:  240 KVHRVFDKYVKKHKKNYKDNKEHHTRREHFKHNLRFIHSKNRRHA----GYYLAMNHLGDRSDKELRV-LRGRRYTKGYNGGLPY-KPDMASINDVPDEMNWVIRGAVTPVKDQAVCGSCWSFGTTGTIEGTLFLKTKYLTRLSQQNLMDCSWGEGNNACDGGEDFRSYQYIMKSGGIATEESYGPYLGADGYCHKKDAEIGATITGYVNITEGDLSALKTAIAQKGPISVSIDASHKSLSFYSYGVYYEPKCGNKNEDLDHSVLAVGYGTMDGKPYWMIKNSWSTHWGMNGYVLMSQ-KDNNCGVATAATYVLM 547

[Close]

BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl.1 (cathepsin L1 [Source:NCBI gene;Acc:101171789])

HSP 1 Score: 364.77 bits (935), Expect = 6.783e-125
Identity = 183/314 (58.28%), Postives = 222/314 (70.70%), Query Frame = 1

Query:  211 EDWELY--KTQFKRQYE-PLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKF----LGKILTRSSTKGSQFMA-PENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYG-LESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ED E +  + +F R Y  P  E  RR  W  N + +  HN+  D G  +Y LG+  +AD+ NEE+K       LG        +GS F   PEN   LP  VDWR KGYVT VK+Q+QCGSCWAFS TGSLEGQ FRKTG LVS SEQQLVDCSG YGN GCGGGLMD+AF YI   G +++E  YPY A DG+C+Y    V  TC+G+ D+  G+E  L  AVAT+GP+SV IDASH SFQLY+ G+Y+EPQCS  +LDHGVLAVGYGSENG +YWLVKNSWG++WG  GYIKMSK+++NQCGI+T+AS+PLV
Sbjct:   27 EDLEFHAWRLKFGRTYSSPTEEAQRRQTWLNNRKLVLVHNILADQGIKSYRLGMTYFADMENEEYKRLISQGCLGSFNASLPRRGSTFFRLPENKD-LPAAVDWRDKGYVTDVKDQKQCGSCWAFSATGSLEGQTFRKTGKLVSLSEQQLVDCSGDYGNMGCGGGLMDDAFRYIQATGGIDTEESYPYEAEDGECRYKPDAVGATCTGYVDVSSGDEDALQEAVATIGPISVGIDASHISFQLYESGLYDEPQCSSSELDHGVLAVGYGSENGQDYWLVKNSWGLTWGDQGYIKMSKNKSNQCGIATAASYPLV 339

[Close]

BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctsl (cathepsin L [Source:NCBI gene;Acc:100049246])

HSP 1 Score: 348.206 bits (892), Expect = 1.919e-118
Identity = 177/319 (55.49%), Postives = 217/319 (68.03%), Query Frame = 1

Query:  190 SLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGK-CKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSE----NGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            +L+ +L++ W+L+K    + Y    E  RR++WE+NL  I  HNLE+ +GKH+Y LG+N + D+T+EEF+    G K   +    GS FM P N    P  VDWR KGYVTPVK+Q QCGSCWAFSTTG+LEGQ FRKTG LVS SEQ LVDCS   GNEGC GGLMD AF Y+    GL+SE  YPY  TD + C+Y+        +GF DI  G E  L  AVA+VGPVSVAIDA H SFQ Y+ GIY E +CS D+LDHGVL VGYG E    +G  YW+VKNSW   WG  G+I M+KDR+N CGI+T+AS+PLV
Sbjct:   19 TLDPQLDQHWQLWKGWHSKNYHEKEEGWRRLVWEKNLRKIELHNLEHSMGKHSYRLGMNHFGDMTHEEFRQIMNGYKRREQRKYSGSLFMEP-NFLEAPRAVDWRDKGYVTPVKDQGQCGSCWAFSTTGALEGQQFRKTGKLVSLSEQNLVDCSRPEGNEGCNGGLMDQAFQYVKDNQGLDSEDFYPYKGTDDQPCQYNAQYSAVNDTGFVDIPSGKERALMKAVASVGPVSVAIDAGHESFQFYQSGIYFEKECSSDELDHGVLVVGYGFEGEDVDGKKYWIVKNSWSEKWGDKGFIYMAKDRHNHCGIATAASYPLV 336

[Close]

BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss (cathepsin S [Source:NCBI gene;Acc:100049247])

HSP 1 Score: 298.516 bits (763), Expect = 4.588e-99
Identity = 151/314 (48.09%), Postives = 196/314 (62.42%), Query Frame = 1

Query:  190 SLNSELNEDWELYKTQFKRQY-EPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMK-YGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            ++ S L++ W L+K  + + Y   + E  RR IWE+NLE I  HNLE  LG H+Y L +N   DLT EE  A   G +      +    +   N  ++P +VDWR  G VT VK Q +CGSCWAFS  G+LEGQ  + TG L S S Q LVDCS  YGN GC GG M NAF Y++K  G+ S+  YPY     KCKYD       C+G+  +  G+E  L V VAT+GP+SVAIDAS   F  Y+ G+Y +  CS + ++HGVL VGYG+ENG +YWLVKNSWG  +G  GYIKM+++R NQCGI+  A FP++
Sbjct:   16 AVRSHLDQHWNLWKKTYSKTYSHEIEEFGRRRIWEENLEMISVHNLEVSLGLHSYELAMNHLGDLTIEELIASLTGTVAPVGLERIHYDLVKINT-SVPESVDWREGGLVTSVKTQGRCGSCWAFSAVGALEGQLKKTTGILTSLSPQNLVDCSTKYGNYGCKGGFMSNAFQYVIKNQGISSDAAYPYIGKRDKCKYDSKHRAANCTGYNFLPKGDEFALKVGVATIGPISVAIDASRPKFLFYRHGVYKDHSCSHN-VNHGVLVVGYGTENGEDYWLVKNSWGERYGDGGYIKMARNRRNQCGIALYACFPVM 327

[Close]

BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: ctss2.1 (cathepsin S [Source:NCBI gene;Acc:101165175])

HSP 1 Score: 286.574 bits (732), Expect = 3.468e-94
Identity = 141/315 (44.76%), Postives = 192/315 (60.95%), Query Frame = 1

Query:  190 SLNSELNEDWELYKTQFKRQYEPLTE-ITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIM-KYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            + +S L+  WEL+K    + Y    E + RR +WE+NL  I  HNLEY +G HTY L +N   DLT EE   +F   +  T    +   F+       +P  +DWR K  VT VK Q  CGSCWAFS  G+LEGQ  RKTG LV  S Q LVDCS  YGN GC GG M  AF Y++   G++S+  YPY      C Y        CS ++ +  G+E  L  A+AT+GP+SVAIDA+   F  Y+ G+Y++  CS + ++HGVLAVGYG+ NG +YWLVKNSWG ++G  GYI+M++++N+QCGI+    +P++
Sbjct:   26 AFDSRLDIHWELWKKTHSKHYPSEEEDVHRRDLWERNLMLITMHNLEYSMGLHTYDLSMNHMGDLTQEEILQQFASLRPPTNLKREPHLFVGASGSNNIPDEMDWRQKNCVTSVKMQGSCGSCWAFSAVGALEGQLCRKTGKLVDLSPQNLVDCSSKYGNHGCNGGFMHQAFQYVIDNQGIDSDAGYPYVGVTQNCHYSSEYRAANCSQYSFLPEGDEGALKEAIATIGPISVAIDATRPRFAFYRSGVYDDSSCSQN-VNHGVLAVGYGTLNGQDYWLVKNSWGTTFGEQGYIRMARNKNDQCGIAMYGCYPIM 339

[Close]

BLAST of Cathepsin L2 vs. Ensembl Medaka
Match: cts12 (cathepsin L1-like [Source:NCBI gene;Acc:101170830])

HSP 1 Score: 284.648 bits (727), Expect = 1.408e-93
Identity = 136/308 (44.16%), Postives = 193/308 (62.66%), Query Frame = 1

Query:  214 DWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFK----AKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            +WE++K+     YE   ++ RR IWE+N   I  HN  +  GK  + +G+N+Y DLT +E++    A    + + R     ++ +      +    VD+R  GYVT VK+Q  CGSCWAFSTTG++EGQ  +KTG L+S SEQ LVDCS  YG  GC G  M +A++Y++  GL++   YPYT+    C YD    V     +  I  G+E  LA AVAT+GP++VAIDA H SF  Y  GIY+EP C P++L H VL VGYGSE G +YW++KNSWG SWG  GY+++ ++ +N CGI++ A +P++
Sbjct:   27 EWEIWKSINGINYEERDDMQRRAIWEENHRMINDHNQRFLTGKRPFSMGMNKYGDLTGQEYRVLQGAVMNAQFVKRGKEVSARRLRYNARKSEAGFVDYRNMGYVTEVKDQGYCGSCWAFSTTGAIEGQIVKKTGQLLSLSEQNLVDCSRPYGTHGCSGAWMASAYDYVLSNGLQTTDSYPYTSDTQPCFYDSRLAVAHIKDYRFIPQGDEQALADAVATIGPITVAIDADHASFLFYSSGIYDEPNCDPNRLSHAVLLVGYGSEEGQDYWIIKNSWGSSWGEGGYMRIIRNGSNTCGIASYALYPIL 334

[Close]

BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014167.1 (SMESG000014167.1)

HSP 1 Score: 694.115 bits (1790), Expect = 0.000e+0
Identity = 331/333 (99.40%), Postives = 332/333 (99.70%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MKAFVLISVFLVAIQARRPTFSLNSELN+DWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSS KGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV
Sbjct:    1 MKAFVLISVFLVAIQARRPTFSLNSELNKDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSRKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 333

[Close]

BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014166.1 (SMESG000014166.1)

HSP 1 Score: 687.182 bits (1772), Expect = 0.000e+0
Identity = 328/334 (98.20%), Postives = 332/334 (99.40%), Query Frame = 1

Query:  127 MKAFVLI-SVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MK++++I SVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDR NQCGISTSASFPLV
Sbjct:    1 MKSYIVILSVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRKNQCGISTSASFPLV 334

[Close]

BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049723.1 (SMESG000049723.1)

HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0
Identity = 236/333 (70.87%), Postives = 286/333 (85.89%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            M+  +L+S+FL A+ A    F++NSELN++WE YKTQF ++Y  L EI+RR+IWEQNL+YI+QHNLE+DLGKHTY LGLN +AD+TNEEF+A +LG +  +     S F+APEN+GALP++VDWRTKG+VTPVKNQQQCGSCW+FSTTGSLEGQH+RKT +L+SFSEQQLVDCSG++GN GC GGLMD+AF YI +YG+E+E  YPYTA DG C YD+SKVVG+C+GF+DI HGNE  LA AVATVGP+SVAIDAS+YSFQLYK GIYNEPQCS  QLDHGVLA+GYG+ENG N+WLVKNSWGI WG+ GYIKMSKD+ NQCGI+T AS+PLV
Sbjct:    1 MQIIILVSLFLAAVSAAPQQFTINSELNDEWEAYKTQFGKKYVSLNEISRRLIWEQNLKYIQQHNLEHDLGKHTYTLGLNHFADMTNEEFRANYLG-VSPKRMNFTSHFIAPENVGALPSSVDWRTKGFVTPVKNQQQCGSCWSFSTTGSLEGQHYRKTQNLISFSEQQLVDCSGSFGNNGCDGGLMDSAFQYIQQYGIEAESTYPYTAQDGNCVYDKSKVVGSCTGFSDIPHGNEQALASAVATVGPISVAIDASNYSFQLYKSGIYNEPQCSSSQLDHGVLAIGYGTENGKNFWLVKNSWGIGWGIQGYIKMSKDQGNQCGIATMASYPLV 332

[Close]

BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000014171.1 (SMESG000014171.1)

HSP 1 Score: 493.812 bits (1270), Expect = 6.541e-176
Identity = 229/333 (68.77%), Postives = 270/333 (81.08%), Query Frame = 1

Query:  127 MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
            MKAF+++S+FLVAI+A    F++NSELNE+WEL+K QF +QYEPLTE+ RRIIWE+NL++IRQHNLEYDLGKH+Y LGLNEY+DLTN EFKAK LG  L  S++KGS+FM PEN+GALP++VDWRTKGYVTPVKNQ  CGSCWAFS TG+LEGQHFRKTG L+S SEQQLVDCS  YGN GCGGG    AF+Y+ KYG+ESE DY Y   + KC YD+SKVV   + +T  K GNESDLA AVATVGP+S+ IDA H  FQ YK GIYN P CS + LDH VL VGYGS NG NYW+VKNSWG  WG+ GYI MSKD++NQCGI+T A +P+V
Sbjct:    1 MKAFIILSLFLVAIEAGPRRFTVNSELNEEWELFKAQFHKQYEPLTEVMRRIIWEENLDFIRQHNLEYDLGKHSYTLGLNEYSDLTNAEFKAKLLGNRLNGSNSKGSEFMVPENIGALPSSVDWRTKGYVTPVKNQYTCGSCWAFSATGALEGQHFRKTGKLISLSEQQLVDCSRPYGNLGCGGGFPYQAFDYVNKYGMESEDDYIYRNKENKCIYDKSKVVANFTSYTFTKPGNESDLAAAVATVGPLSIGIDADHPGFQHYKNGIYNNPTCSSEYLDHAVLVVGYGSLNGNNYWIVKNSWGPHWGIEGYILMSKDKDNQCGIATQAVYPVV 333

[Close]

BLAST of Cathepsin L2 vs. Planmine SMEST
Match: SMESG000049722.1 (SMESG000049722.1)

HSP 1 Score: 484.952 bits (1247), Expect = 1.725e-172
Identity = 228/332 (68.67%), Postives = 271/332 (81.63%), Query Frame = 1

Query:  136 FVLISVF-LVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITRRIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLG-KILTRSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGSLEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLESERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVSVAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKNSWGISWGLSGYIKMSKDRNNQCGISTSASFPLV 1125
             VL++VF +V+I A +  F +N  LNE+W +YK QF+R+YE + E+TRR+IWE+NL  I++HN+EYDLGKH+YYLGLNE+AD+TNEE++ K LG K + ++ T+ + F+APEN   LP +VDWRTKGYVTPVKNQ  CGSCW+FSTTGSLEGQH RKTG L+S SEQQLVDCS  +GN GC GGLMDNAF YI KYGLESE DY YTA +G CKYD SKVV  C+GF DIK GNE DLA AVATVGP+SVAIDAS  +FQLYKGGIYNE  CS  QLDHGVLAVGYG EN  ++W+VKNSWG  WGLSGYIKM+KDR+NQCGI+T AS+PLV
Sbjct:    3 IVLLAVFCVVSISAGKLKFEVNEALNEEWNMYKIQFQRKYESIIELTRRLIWEENLRLIQKHNIEYDLGKHSYYLGLNEFADMTNEEYRVKVLGLKPINKNYTR-TIFLAPENTVDLPKSVDWRTKGYVTPVKNQANCGSCWSFSTTGSLEGQHKRKTGQLISLSEQQLVDCSKPFGNNGCNGGLMDNAFQYIQKYGLESEADYSYTAKEGNCKYDASKVVAHCTGFVDIKKGNEKDLAKAVATVGPISVAIDASKPTFQLYKGGIYNEKSCSSRQLDHGVLAVGYGKENNQHFWIVKNSWGPQWGLSGYIKMTKDRHNQCGIATMASYPLV 333

The following BLAST results are available for this feature:

BLAST of Cathepsin L2 vs. Ensembl Human
BLAST of Cathepsin L2 vs. Ensembl Celegans
BLAST of Cathepsin L2 vs. Ensembl Fly
BLAST of Cathepsin L2 vs. Ensembl Zebrafish
BLAST of Cathepsin L2 vs. Ensembl Xenopus
BLAST of Cathepsin L2 vs. Ensembl Mouse
BLAST of Cathepsin L2 vs. UniProt/SwissProt
BLAST of Cathepsin L2 vs. TrEMBL
BLAST of Cathepsin L2 vs. Ensembl Cavefish
BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
BLAST of Cathepsin L2 vs. Ensembl Yeast
BLAST of Cathepsin L2 vs. Ensembl Nematostella
BLAST of Cathepsin L2 vs. Ensembl Medaka
BLAST of Cathepsin L2 vs. Planmine SMEST

BLAST of Cathepsin L2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
CTSV	3.277e-118	52.07	cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]	[more]
CTSV	3.277e-118	52.07	cathepsin V [Source:HGNC Symbol;Acc:HGNC:2538]	[more]
CTSL	1.027e-115	51.48	cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]	[more]
CTSL	1.027e-115	51.48	cathepsin L [Source:HGNC Symbol;Acc:HGNC:2537]	[more]
CTSK	2.730e-106	50.79	cathepsin K [Source:HGNC Symbol;Acc:HGNC:2536]	[more]

BLAST of Cathepsin L2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
cpl-1	1.180e-104	49.04	CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H...	[more]
cpl-1	1.163e-80	57.87	CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H...	[more]
cpl-1	1.163e-80	57.87	CathePsin L family [Source:UniProtKB/TrEMBL;Acc:H...	[more]
tag-196	8.441e-54	36.27	pep chromosome:WBcel235:V:8594914:8597500:1 gene:W...	[more]
tag-196	8.441e-54	36.27	pep chromosome:WBcel235:V:8594914:8597469:1 gene:W...	[more]

BLAST of Cathepsin L2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Cp1	9.462e-115	53.16	gene:FBgn0013770 transcript:FBtr0087592	[more]
Cp1	1.081e-114	53.16	gene:FBgn0013770 transcript:FBtr0087593	[more]
Cp1	3.763e-111	53.90	gene:FBgn0013770 transcript:FBtr0339955	[more]
Cp1	2.295e-101	61.80	gene:FBgn0013770 transcript:FBtr0304021	[more]
CG5367	2.158e-68	34.70	gene:FBgn0032228 transcript:FBtr0080055	[more]

BLAST of Cathepsin L2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctsla	2.271e-122	53.57	cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106]	[more]
ctsla	2.271e-122	53.57	cathepsin La [Source:ZFIN;Acc:ZDB-GENE-030131-106]	[more]
ctsl.1	2.313e-122	55.91	cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]	[more]
ctsl.1	2.313e-122	55.91	cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]	[more]
ctsl.1	2.313e-122	55.91	cathepsin L.1 [Source:ZFIN;Acc:ZDB-GENE-040718-61]	[more]

BLAST of Cathepsin L2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
fcrl2	6.258e-125	52.79	Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590...	[more]
fcrl2	2.395e-124	52.80	Fc receptor-like 2 [Source:Xenbase;Acc:XB-GENE-590...	[more]
ano1	1.178e-108	45.86	anoctamin 1, calcium activated chloride channel [S...	[more]
harbi1	4.470e-101	45.71	harbinger transposase derived 1 [Source:Xenbase;Ac...	[more]
ctsk	1.324e-100	46.50	cathepsin K (pycnodysostosis) [Source:NCBI gene;Ac...	[more]

BLAST of Cathepsin L2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ctsl	2.894e-111	52.98	cathepsin L [Source:MGI Symbol;Acc:MGI:88564]	[more]
Ctsl	2.894e-111	52.98	cathepsin L [Source:MGI Symbol;Acc:MGI:88564]	[more]
Ctsll3	1.792e-107	48.66	cathepsin L-like 3 [Source:MGI Symbol;Acc:MGI:1917...	[more]
BC051665	2.008e-104	47.76	cDNA sequence BC051665 [Source:MGI Symbol;Acc:MGI:...	[more]
Ctss	1.654e-102	48.05	cathepsin S [Source:MGI Symbol;Acc:MGI:107341]	[more]

BLAST of Cathepsin L2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P25782\|CYSP2_HOMAM	3.771e-121	54.60	Digestive cysteine proteinase 2 OS=Homarus america...	[more]
sp\|O60911\|CATL2_HUMAN	1.574e-117	52.07	Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 ...	[more]
sp\|Q9GKL8\|CATL1_CHLAE	6.584e-116	53.13	Cathepsin L1 OS=Chlorocebus aethiops OX=9534 GN=CT...	[more]
sp\|P07711\|CATL1_HUMAN	4.934e-115	51.48	Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 ...	[more]
sp\|Q95029\|CATL_DROME	1.084e-113	53.16	Cathepsin L OS=Drosophila melanogaster OX=7227 GN=...	[more]

BLAST of Cathepsin L2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A2U8U447	1.404e-179	70.66	Cathepsin L2 OS=Dugesia japonica OX=6161 PE=2 SV=1	[more]
A0A267H1I6	1.465e-144	61.38	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A1I8GVB7	1.689e-144	61.38	Uncharacterized protein OS=Macrostomum lignano OX=...	[more]
A0A0L8HPF9	4.846e-138	58.75	Uncharacterized protein OS=Octopus bimaculoides OX...	[more]
A0A0N9WMD3	1.542e-137	58.38	Cathepsin L OS=Cerebratulus lacteus OX=6221 PE=2 S...	[more]

BLAST of Cathepsin L2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-26g8.5	1.488e-120	54.23	cathepsin L1-like [Source:NCBI gene;Acc:103028700]	[more]
ctsl.1	8.600e-119	54.81	cathepsin L1-like [Source:NCBI gene;Acc:103023607]	[more]
ENSAMXT00000042132.1	1.315e-116	50.74	cathepsin L1-like [Source:NCBI gene;Acc:103023924]	[more]
ENSAMXT00000048039.1	1.315e-116	50.74	cathepsin L1-like [Source:NCBI gene;Acc:103023924]	[more]
ENSAMXT00000047972.1	1.614e-114	53.85	pep primary_assembly:Astyanax_mexicanus-2.0:APWO02...	[more]

BLAST of Cathepsin L2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000006499.1	1.494e-125	54.17	pep scaffold:Pmarinus_7.0:GL477089:42202:47941:1 g...	[more]
ENSPMAT00000011285.1	2.329e-113	56.52	pep scaffold:Pmarinus_7.0:GL499136:454:1347:-1 gen...	[more]
ENSPMAT00000010475.1	6.703e-110	56.40	pep scaffold:Pmarinus_7.0:GL482653:10321:33550:-1 ...	[more]
ENSPMAT00000008535.1	1.299e-107	49.10	pep scaffold:Pmarinus_7.0:GL478103:36116:54424:1 g...	[more]
ENSPMAT00000003800.1	1.361e-104	55.52	pep scaffold:Pmarinus_7.0:GL485125:12828:20107:1 g...	[more]

BLAST of Cathepsin L2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Cathepsin L2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46465	2.607e-131	57.14	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45953	3.684e-120	52.82	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO36727	2.706e-116	50.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO45852	4.373e-116	49.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41322	4.634e-67	38.41	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Cathepsin L2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ctsl.1	6.783e-125	58.28	cathepsin L1 [Source:NCBI gene;Acc:101171789]	[more]
ctsl	1.919e-118	55.49	cathepsin L [Source:NCBI gene;Acc:100049246]	[more]
ctss	4.588e-99	48.09	cathepsin S [Source:NCBI gene;Acc:100049247]	[more]
ctss2.1	3.468e-94	44.76	cathepsin S [Source:NCBI gene;Acc:101165175]	[more]
cts12	1.408e-93	44.16	cathepsin L1-like [Source:NCBI gene;Acc:101170830]	[more]

BLAST of Cathepsin L2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014167.1	0.000e+0	99.40	SMESG000014167.1	[more]
SMESG000014166.1	0.000e+0	98.20	SMESG000014166.1	[more]
SMESG000049723.1	0.000e+0	70.87	SMESG000049723.1	[more]
SMESG000014171.1	6.541e-176	68.77	SMESG000014171.1	[more]
SMESG000049722.1	1.725e-172	68.67	SMESG000049722.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30035609 ID=SMED30035609|Name=Cathepsin L2|organism=Schmidtea mediterranea sexual|type=transcript|length=1185bp
TGAGATTTAGGCTTGATGTCATATAATTGTGACCCGATCACAAGTTTTAT
CACAAGCTGATCATGAAATTGAACCTTGGAAGCAGGCCTACTATAAAAAC
AAAATTTACACCGACAGAATTATAAAATGAAAGCTTTCGTTTTAATATCC
GTTTTCCTTGTGGCTATTCAAGCTAGACGTCCGACCTTCTCACTCAACAG
CGAGTTGAATGAAGATTGGGAACTATACAAGACTCAGTTCAAAAGACAGT
ACGAACCCCTCACTGAAATCACGAGAAGAATCATCTGGGAACAAAACCTT
GAATACATTCGACAACATAACCTCGAGTATGATCTGGGAAAACATACTTA
CTACTTGGGATTGAATGAATACGCTGATCTAACTAATGAAGAATTTAAAG
CCAAATTTTTGGGAAAAATATTGACTAGATCATCAACAAAAGGATCTCAA
TTTATGGCTCCAGAAAATATGGGAGCTTTGCCTACGACTGTGGACTGGAG
AACTAAAGGATACGTAACTCCAGTTAAAAATCAACAACAATGCGGATCGT
GTTGGGCTTTCTCGACTACTGGATCTCTTGAAGGTCAACATTTTAGGAAG
ACTGGAAGTTTAGTTAGTTTCTCAGAACAACAATTAGTTGATTGCAGCGG
TGCTTATGGAAATGAAGGATGTGGCGGAGGATTAATGGACAATGCATTCA
ATTATATAATGAAATATGGCTTGGAATCAGAGAGAGATTACCCATATACT
GCAACTGACGGAAAATGTAAGTATGACAGGTCAAAAGTGGTTGGAACATG
CAGTGGATTTACGGATATTAAACATGGAAACGAATCTGATTTGGCAGTTG
CGGTAGCAACTGTAGGACCCGTGTCGGTAGCAATTGATGCCAGTCACTAC
AGCTTCCAATTATACAAGGGAGGAATTTACAATGAGCCCCAATGTTCTCC
TGACCAATTGGATCACGGAGTTTTGGCAGTCGGTTATGGATCAGAGAATG
GAGGCAACTATTGGCTAGTGAAAAATAGCTGGGGTATTTCTTGGGGCCTT
TCTGGATACATCAAAATGTCAAAGGACAGAAACAATCAGTGTGGAATCTC
CACCTCTGCAAGCTTTCCATTAGTTTAATTTGAACTATTATATTAATTTT
TCCAACTTAATTTTTATATTTAATAAACTTTGCTT

protein sequence of SMED30035609-orf-1

>SMED30035609-orf-1 ID=SMED30035609-orf-1|Name=SMED30035609-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=334bp
MKAFVLISVFLVAIQARRPTFSLNSELNEDWELYKTQFKRQYEPLTEITR
RIIWEQNLEYIRQHNLEYDLGKHTYYLGLNEYADLTNEEFKAKFLGKILT
RSSTKGSQFMAPENMGALPTTVDWRTKGYVTPVKNQQQCGSCWAFSTTGS
LEGQHFRKTGSLVSFSEQQLVDCSGAYGNEGCGGGLMDNAFNYIMKYGLE
SERDYPYTATDGKCKYDRSKVVGTCSGFTDIKHGNESDLAVAVATVGPVS
VAIDASHYSFQLYKGGIYNEPQCSPDQLDHGVLAVGYGSENGGNYWLVKN
SWGISWGLSGYIKMSKDRNNQCGISTSASFPLV*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000070	intestinal phagocyte
PLANA:0000420	parapharyngeal region

Vocabulary: **INTERPRO**
Term	Definition
IPR039417	Peptidase_C1A_papain-like
IPR038765	Papain-like_cys_pep_sf
IPR000668	Peptidase_C1A_C
IPR013201	Prot_inhib_I29
IPR000169	Pept_cys_AS
IPR025661	Pept_asp_AS
IPR025660	Pept_his_AS

Vocabulary: **molecular function**
Term	Definition
GO:0008234	cysteine-type peptidase activity
GO:0008233	peptidase activity
GO:0016787	hydrolase activity

Vocabulary: **biological process**
Term	Definition
GO:0006508	proteolysis

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR000668	Peptidase C1A, papain C-terminal	PRINTS	PR00705	PAPAIN	coord: 280..290 score: 61.1 coord: 136..151 score: 61.2 coord: 295..301 score: 75.76
IPR000668	Peptidase C1A, papain C-terminal	SMART	SM00645	pept_c1	coord: 118..332 e-value: 9.9E-125 score: 430.4
IPR000668	Peptidase C1A, papain C-terminal	PFAM	PF00112	Peptidase_C1	coord: 118..331 e-value: 2.2E-84 score: 282.9
IPR013201	Cathepsin propeptide inhibitor domain (I29)	SMART	SM00848	Inhibitor_I29_2	coord: 31..90 e-value: 4.8E-24 score: 95.9
IPR013201	Cathepsin propeptide inhibitor domain (I29)	PFAM	PF08246	Inhibitor_I29	coord: 31..90 e-value: 8.3E-12 score: 45.4
None	No IPR available	GENE3D	G3DSA:3.90.70.10		coord: 28..333 e-value: 8.6E-115 score: 385.6
None	No IPR available	PANTHER	PTHR12411:SF631		coord: 21..332
None	No IPR available	PANTHER	PTHR12411	CYSTEINE PROTEASE FAMILY C1-RELATED	coord: 21..332
None	No IPR available	SIGNALP_EUK	SignalP-noTM	SignalP-noTM	coord: 1..16 score: 0.697
IPR000169	Cysteine peptidase, cysteine active site	PROSITE	PS00139	THIOL_PROTEASE_CYS	coord: 136..147
IPR025660	Cysteine peptidase, histidine active site	PROSITE	PS00639	THIOL_PROTEASE_HIS	coord: 278..288
IPR025661	Cysteine peptidase, asparagine active site	PROSITE	PS00640	THIOL_PROTEASE_ASN	coord: 295..314
IPR039417	Papain-like cysteine endopeptidase	CDD	cd02248	Peptidase_C1A	coord: 119..331 e-value: 2.31864E-124 score: 353.467
IPR038765	Papain-like cysteine peptidase superfamily	SUPERFAMILY	SSF54001	Cysteine proteinases	coord: 23..332

Main menu

Cathepsin L2

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 12

Owlery

blazegraph-runner