Tau tubulin kinase 1a

Overview


Name	Tau tubulin kinase 1a
Smed ID	SMED30035594
Length (bp)	5145

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Tau tubulin kinase 1a (SMED30035594) t-SNE clustered cells

Violin plots show distribution of expression levels for Tau tubulin kinase 1a (SMED30035594) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Tau tubulin kinase 1a (SMED30035594) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Tau tubulin kinase 1a (SMED30035594) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035594

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 18

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30035594	SMESG000068893.1	dd_Smed_v4_8160_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30035594	SMESG000068893.1	dd_Smed_v4_8160_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
protonephridia	SMED30035594	SMESG000046962.1 SMESG000046951.1 SMESG000040592.1 SMESG000034034.1	dd_Smed_v4_489_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30035594	SMESG000046962.1 SMESG000046951.1 SMESG000040592.1 SMESG000034034.1	dd_Smed_v4_489_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30035594	SMESG000046962.1 SMESG000046951.1 SMESG000040592.1 SMESG000034034.1	dd_Smed_v4_489_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035594	SMESG000040592.1	Contig47362	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30035594	SMESG000040592.1	Contig47362	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
pharynx	SMED30035594	SMESG000040592.1	KX681482	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
gut	SMED30035594	SMESG000040592.1	KX681482	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
cephalic ganglia	SMED30035594	SMESG000040592.1	KX681482	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
neoblast	SMED30035594	SMESG000040592.1	KX681482	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
neoblast	SMED30035594	SMESG000040592.1	LPT	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
neoblast	SMED30035594	SMESG000040592.1	LPT	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
parenchyma	SMED30035594	SMESG000040592.1	LPT	smed_ncbi_20200123	PMID:30194301 Mihaylova et al., 2018
reproductive organ	SMED30035594	SMESG000068893.1	Contig48448	newmark_ests	PMID:28434803 Rouhana et al., 2017
reproductive organ	SMED30035594	SMESG000068893.1	Contig48448	uc_Smed_v2	PMID:28434803 Rouhana et al., 2017
epidermis	SMED30035594	SMESG000068893.1	dd_Smed_v4_8160_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30035594	SMESG000046962.1 SMESG000046951.1 SMESG000040592.1 SMESG000034034.1	dd_Smed_v4_489_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Tau tubulin kinase 1a vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 439.113 bits (1128), Expect = 2.745e-138
Identity = 199/290 (68.62%), Postives = 238/290 (82.07%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

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BLAST of Tau tubulin kinase 1a vs. Ensembl Human
Match: TTBK1 (tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140])

HSP 1 Score: 451.44 bits (1160), Expect = 2.249e-133
Identity = 198/293 (67.58%), Postives = 239/293 (81.57%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L   Y++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRN+KFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  +H +LL+HMP EF   LDHI  L YF KPDY  + ++ + +M  +     + FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

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BLAST of Tau tubulin kinase 1a vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 446.047 bits (1146), Expect = 4.122e-132
Identity = 199/290 (68.62%), Postives = 238/290 (82.07%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

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BLAST of Tau tubulin kinase 1a vs. Ensembl Human
Match: TTBK1 (tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:19140])

HSP 1 Score: 397.127 bits (1019), Expect = 4.307e-120
Identity = 178/260 (68.46%), Postives = 211/260 (81.15%), Query Frame = 1

Query:  217 IDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            +DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRN+KFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  +H +LL+HMP EF   LDHI  L YF KPDY  + ++ + +M  +     + FDWE
Sbjct:    1 MDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 260

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BLAST of Tau tubulin kinase 1a vs. Ensembl Human
Match: TTBK2 (tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:19141])

HSP 1 Score: 363.229 bits (931), Expect = 2.154e-111
Identity = 172/290 (59.31%), Postives = 208/290 (71.72%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL +Q+LE IESIHSVGFLHRDIK                                   PPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIK-----------------------------------PPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 263

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BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
Match: ttbk-7 (Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:Q22033])

HSP 1 Score: 383.645 bits (984), Expect = 6.546e-115
Identity = 170/297 (57.24%), Postives = 223/297 (75.08%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQ-EKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEI 999
            +S   ++L+ G +I+ERW++  KIGGGGFG+IYEA D+ +  E+VA+K+ES++ +KQVLKMEVAVL++LQG  H C+FYGCGRNDKFNY+VMSLQGKNL +LRR   K  F++S+ VR+  Q+L  I  IHS+GFLHRD+KPSNFAMGR   T R VYMLDFGLARQY+N  GE+R PR  AGFRGTVRYA+  AH NKE+GR DDLWSL Y+  E + GQLPWRK+KDK++VGK+K+  D  +LL   P E    + H++ L Y   PDY  L++LL++ +A     + +P+DWE+
Sbjct:    3 SSSEGEILQVGQVIRERWKIKAKIGGGGFGEIYEATDVQNHHERVAIKVESSKATKQVLKMEVAVLRRLQGKKHACKFYGCGRNDKFNYLVMSLQGKNLADLRREAPKQCFNLSTAVRVGIQILNGIREIHSIGFLHRDVKPSNFAMGRTSQTMRNVYMLDFGLARQYLNAKGEIRSPRSAAGFRGTVRYAAVTAHKNKEMGRQDDLWSLFYMLTEFLQGQLPWRKIKDKDEVGKMKEEADLVVLLDDCPHEMHLFVAHLKVLGYADTPDYVYLESLLNKIVAENEISWDEPYDWEL 299

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BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
Match: ttbk-2 (Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:O76712])

HSP 1 Score: 242.276 bits (617), Expect = 2.490e-71
Identity = 123/287 (42.86%), Postives = 179/287 (62.37%), Query Frame = 1

Query:  157 ERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKL--QGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLP-STFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQ---NVDHNLLLRHMPL-EFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            ERW + KK+G GG G +Y   D +   K ALK+E   ++ QVLKMEV VL +L  +G  H C+    GR   FNYVVM+L GK+L +LR+ T++   S++  + +  Q LE +E +H++G+LHRD+KP N+ +GR   +  RKVY+LDFG+AR++ + +G +R PR  AGFRGTVRYA    H N+ELGR DD+   LY+ VE+  G++PW+++ D   VG+ KQ   N    + +   P  E K+I+  +    YFA P+Y+    L+ QT+A    K   P+DWE
Sbjct:   18 ERWSITKKLGEGGCGAVYLCTDATG--KYALKVEGISEAMQVLKMEVLVLGELTKRGSRHFCKIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGNYTIGRAELNELRKVYILDFGMARKFTDNNGVIRKPRAAAGFRGTVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMNAVGQAKQAIRNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQTLA-NCGKPEYPYDWE 301

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BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
Match: R13H9.5 (pep chromosome:WBcel235:IV:5065746:5066987:-1 gene:WBGene00020071.1 transcript:R13H9.5.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:R13H9.5)

HSP 1 Score: 240.35 bits (612), Expect = 1.076e-70
Identity = 122/287 (42.51%), Postives = 178/287 (62.02%), Query Frame = 1

Query:  157 ERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKL--QGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLP-STFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQ---NVDHNLLLRHMPL-EFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            ERW + KK+G GG G +Y   D +   K ALK+E   ++ QVLKMEV VL +L  +G  H C+    GR   FNYVVM+L GK+L +LR+ T++   S++  + +  Q LE +E +H++G+LHRD+KP N+ +GR   +  RKVY+LDFG+AR++ + +G +R PR  AGFRGTVRYA    H N+ELGR DD+   LY+ VE+  G++PW+++ D   VG+ KQ   N    + +   P  E K+I+  +    YFA P+Y+    L+ Q +A    K   P+DWE
Sbjct:   18 ERWSITKKLGEGGCGAVYLCTDATG--KYALKVEGISEAMQVLKMEVLVLGELTKRGSRHFCKIEDKGRYGSFNYVVMTLVGKSLQDLRKGTAQQCLSLACSLSVGIQSLEALEDLHNIGYLHRDVKPGNYTIGRAELNELRKVYILDFGMARKFTDNNGVIRKPRAAAGFRGTVRYAPIACHKNQELGRKDDVEVWLYMQVELTVGRVPWKEITDMNAVGQAKQTIRNTPEKMFVFPCPANELKEIMKMVDSWDYFADPNYADCYRLMKQALA-NCGKPEYPYDWE 301

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BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
Match: Y38H8A.3 (pep chromosome:WBcel235:IV:13472497:13474005:1 gene:WBGene00012637.1 transcript:Y38H8A.3.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y38H8A.3)

HSP 1 Score: 234.958 bits (598), Expect = 7.996e-69
Identity = 119/294 (40.48%), Postives = 176/294 (59.86%), Query Frame = 1

Query:  133 LEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKL--QGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLP-STFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHN---LLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            L PG  + ERW + KK+G GGFG +Y   D +   K A+K+E A +  QVLK+EV+VL KL  +G  H C+    GR   FNYVVM+L GK+L +L +A   G  S+   + +  Q LE +E +H++G+LHRD+KP N+ +GR   +  RKVY+LDFG+ R++   DG +R PR  AGFRGTV+YA  + H  +EL R DDL + +Y+ VE+  G +PW+ + D  QVG+ KQ + +N   L     P +F+ I+  +  + Y+  P+Y  +  ++ Q           P+DWE
Sbjct:    8 LNPGQQV-ERWSIEKKLGEGGFGAVYRVFDATG--KYAMKVEGANEQIQVLKLEVSVLNKLSKRGNRHFCKIEDKGRFGNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGTIRKPRQAAGFRGTVKYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQYISDMNQVGQAKQAIRNNLGSLFPPPCPHQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE 298

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BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
Match: C39H7.1 (pep chromosome:WBcel235:IV:5631895:5633379:1 gene:WBGene00016541.1 transcript:C39H7.1.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C39H7.1)

HSP 1 Score: 234.187 bits (596), Expect = 1.307e-68
Identity = 118/294 (40.14%), Postives = 176/294 (59.86%), Query Frame = 1

Query:  133 LEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKL--QGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLP-STFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHN---LLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            L PG  + ERW + KK+G GGFG +Y   D +   K A+K+E A +  QVLK+EV+VL +L  +G  H C+    GR   FNYVVM+L GK+L +L +A   G  S+   + +  Q LE +E +H++G+LHRD+KP N+ +GR   +  RKVY+LDFG+ R++   DG +R PR  AGFRGTV+YA  + H  +EL R DDL + +Y+ VE+  G +PW+ + D  QVG+ KQ + +N   L     P +F+ I+  +  + Y+  P+Y  +  ++ Q           P+DWE
Sbjct:    8 LNPGQQV-ERWSIEKKLGEGGFGAVYRVFDATG--KYAMKVEGANEQIQVLKLEVSVLNELSKRGNRHFCKIEDKGRFGNFNYVVMTLVGKSLQDLNKAGVGGHMSMGCSIGIGIQSLEALEDLHNIGYLHRDVKPGNYTIGRPELNEIRKVYILDFGMCRKFTGNDGTIRKPRQAAGFRGTVKYAPISCHLQRELCRKDDLETWMYMQVELSHGTIPWQHISDMNQVGQAKQAIRNNLGTLFPPPCPQQFQDIMRMVDAMKYYDAPNYQAIYGMMRQAYGACGSNENAPYDWE 298

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BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0300344)

HSP 1 Score: 442.965 bits (1138), Expect = 1.216e-135
Identity = 199/294 (67.69%), Postives = 239/294 (81.29%), Query Frame = 1

Query:  121 SSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            S DLL+PG+++KERW+V +KIGGGGFG+IYE  DL ++E+VALK+ESA+Q KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQGKNL ELRRA  +G FS+S+ +RL  Q+L+ IESIHSVGFLHRDIKPSNF++GRLP   R+VYMLDFGLARQY    GEVR PR  AGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG  K+  DH +LL+H+P + KQ L+HIQ L Y  +PDY+ L  L ++ M R+  K +DP+DWE V
Sbjct:    3 SEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKV 296

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BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0344869)

HSP 1 Score: 444.506 bits (1142), Expect = 4.949e-133
Identity = 199/294 (67.69%), Postives = 239/294 (81.29%), Query Frame = 1

Query:  121 SSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            S DLL+PG+++KERW+V +KIGGGGFG+IYE  DL ++E+VALK+ESA+Q KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQGKNL ELRRA  +G FS+S+ +RL  Q+L+ IESIHSVGFLHRDIKPSNF++GRLP   R+VYMLDFGLARQY    GEVR PR  AGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG  K+  DH +LL+H+P + KQ L+HIQ L Y  +PDY+ L  L ++ M R+  K +DP+DWE V
Sbjct:    3 SEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKV 296

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BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332908)

HSP 1 Score: 444.506 bits (1142), Expect = 4.949e-133
Identity = 199/294 (67.69%), Postives = 239/294 (81.29%), Query Frame = 1

Query:  121 SSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            S DLL+PG+++KERW+V +KIGGGGFG+IYE  DL ++E+VALK+ESA+Q KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQGKNL ELRRA  +G FS+S+ +RL  Q+L+ IESIHSVGFLHRDIKPSNF++GRLP   R+VYMLDFGLARQY    GEVR PR  AGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG  K+  DH +LL+H+P + KQ L+HIQ L Y  +PDY+ L  L ++ M R+  K +DP+DWE V
Sbjct:    3 SEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKV 296

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BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332904)

HSP 1 Score: 444.506 bits (1142), Expect = 1.094e-132
Identity = 214/353 (60.62%), Postives = 261/353 (73.94%), Query Frame = 1

Query:  121 SSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNNENSNA 1179
            S DLL+PG+++KERW+V +KIGGGGFG+IYE  DL ++E+VALK+ESA+Q KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQGKNL ELRRA  +G FS+S+ +RL  Q+L+ IESIHSVGFLHRDIKPSNF++GRLP   R+VYMLDFGLARQY    GEVR PR  AGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG  K+  DH +LL+H+P + KQ L+HIQ L Y  +PDY+ L  L ++ M R+  K +DP+DWE V     +ST   N   + A  N  I  +  S Y  GN    T   +  +  E  ++N NA
Sbjct:  159 SEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKV-----DSTAIGN---ISATGNPSIPIK--SDYMHGNITQMTVAASNASGTEYVDKNCNA 501

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BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
Match: Asator (gene:FBgn0039908 transcript:FBtr0332905)

HSP 1 Score: 444.891 bits (1143), Expect = 1.979e-132
Identity = 199/294 (67.69%), Postives = 239/294 (81.29%), Query Frame = 1

Query:  121 SSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            S DLL+PG+++KERW+V +KIGGGGFG+IYE  DL ++E+VALK+ESA+Q KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQGKNL ELRRA  +G FS+S+ +RL  Q+L+ IESIHSVGFLHRDIKPSNF++GRLP   R+VYMLDFGLARQY    GEVR PR  AGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG  K+  DH +LL+H+P + KQ L+HIQ L Y  +PDY+ L  L ++ M R+  K +DP+DWE V
Sbjct:    3 SEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKV 296

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BLAST of Tau tubulin kinase 1a vs. Ensembl Zebrafish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 459.529 bits (1181), Expect = 7.991e-137
Identity = 200/295 (67.80%), Postives = 244/295 (82.71%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            T++  D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPSTFRK YMLDFGLARQY NT+GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH +LL+HMP EF   L+H+  L Y+ KPDY  L ++ + +M  ++    +P+DWE
Sbjct:    4 TAEQQDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYTNTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWE 298

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Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            T++  D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPSTFRK YMLDFGLARQY NT+GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH +LL+HMP EF   L+H+  L Y+ KPDY  L ++ + +M  ++    +P+DWE
Sbjct:    4 TAEQQDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYTNTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWE 298

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BLAST of Tau tubulin kinase 1a vs. Ensembl Zebrafish
Match: ttbk1b (tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-100609-5])

HSP 1 Score: 447.588 bits (1150), Expect = 5.248e-133
Identity = 198/290 (68.28%), Postives = 238/290 (82.07%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L    ++K+RW+V KKIGGGGFG+IYEA DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G FS+S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST RK YMLDFGLARQY NT+GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  +H +LL+HMP EF    DH+ +L YF KPDY  L ++ + +M  ++    +P+DWE
Sbjct:   22 DILPSNCLVKDRWKVLKKIGGGGFGEIYEAYDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTCRKCYMLDFGLARQYTNTNGEVRPPRSVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHRMLLKHMPAEFHIFYDHVLDLDYFTKPDYQLLMSVFENSMKDRVITENEPYDWE 311

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BLAST of Tau tubulin kinase 1a vs. Ensembl Zebrafish
Match: ttbk2a (tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-120928-3])

HSP 1 Score: 442.58 bits (1137), Expect = 1.494e-132
Identity = 199/297 (67.00%), Postives = 236/297 (79.46%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEP 1017
            D+L  G ++KERW++ KKIGGGGFG+IYEA+DL ++  VALK ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ ++G F++S+ +RL  Q+LE IESIHSVGFLHRDIKPSNFAMGR PST R  YMLDFGLARQ+ N+  EVRPPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRK+KDKEQVGKLK+  DH L+L+H+P +F   LDHI  L YF KPDY  L+ + + +M        DP+DWE +    P
Sbjct:    9 DILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFTNSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWERISSDSP 305

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BLAST of Tau tubulin kinase 1a vs. Ensembl Zebrafish
Match: ttbk2a (tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-120928-3])

HSP 1 Score: 444.121 bits (1141), Expect = 4.389e-132
Identity = 199/297 (67.00%), Postives = 236/297 (79.46%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEP 1017
            D+L  G ++KERW++ KKIGGGGFG+IYEA+DL ++  VALK ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ ++G F++S+ +RL  Q+LE IESIHSVGFLHRDIKPSNFAMGR PST R  YMLDFGLARQ+ N+  EVRPPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRK+KDKEQVGKLK+  DH L+L+H+P +F   LDHI  L YF KPDY  L+ + + +M        DP+DWE +    P
Sbjct:    9 DILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFTNSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWERISSDSP 305

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BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 449.129 bits (1154), Expect = 1.544e-137
Identity = 206/305 (67.54%), Postives = 246/305 (80.66%), Query Frame = 1

Query:   97 SMPSPTSDSS-----DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            S P+PT+ S      D+L  G ++KERW+V +KIGGGGFG+IY+A+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G FSIS+M+RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  +H L+L+H+P EF   L+HI  L YF KPDY  L ++ D +M       +DPFDWE
Sbjct:    5 SAPTPTAMSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 309

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BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 447.973 bits (1151), Expect = 3.900e-133
Identity = 201/290 (69.31%), Postives = 239/290 (82.41%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G FSIS+M+RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  +H L+L+H+P EF   L+HI  L YF KPDY  L ++ D +M       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 448.743 bits (1153), Expect = 1.085e-132
Identity = 201/290 (69.31%), Postives = 239/290 (82.41%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G FSIS+M+RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  +H L+L+H+P EF   L+HI  L YF KPDY  L ++ D +M       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 426.017 bits (1094), Expect = 2.216e-129
Identity = 193/274 (70.44%), Postives = 227/274 (82.85%), Query Frame = 1

Query:  175 KKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            +KIGGGGFG+IY+A+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G FSIS+M+RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  +H L+L+H+P EF   L+HI  L YF KPDY  L ++ D +M       +DPFDWE
Sbjct:   22 RKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 295

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
Match: col24a1 (collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:XB-GENE-980334])

HSP 1 Score: 364.385 bits (934), Expect = 8.462e-112
Identity = 175/297 (58.92%), Postives = 211/297 (71.04%), Query Frame = 1

Query:  106 SPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            S   +  D+L  G ++KERW+V +KIGGGGFG+IY+A+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G FSIS+M+RL +Q+LE IESIHSVGFLHRDIK                                   PPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  +H L+L+H+P EF   L+HI  L YF KPDY  L ++ D +M       +DPFDWE
Sbjct:    2 SGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFSISTMLRLGRQILESIESIHSVGFLHRDIK-----------------------------------PPRAVAGFRGTVRYASVNAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYEHRLMLKHLPPEFSVFLEHIIGLDYFTKPDYQLLVSVFDNSMKTFGVLESDPFDWE 263

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Mouse
Match: Ttbk1 (tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:2147036])

HSP 1 Score: 445.662 bits (1145), Expect = 4.108e-137
Identity = 198/293 (67.58%), Postives = 239/293 (81.57%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L   Y++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRN+KFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  +H +LL+HMP EF   LDHI  L YF KPDY  + ++ + +M  +     + FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 444.121 bits (1141), Expect = 2.762e-135
Identity = 199/293 (67.92%), Postives = 239/293 (81.57%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            +  D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL KQ+LE IESIHSVGFLHRDIKPSNFAMGR PST RK +MLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    6 EQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Mouse
Match: Ttbk1 (tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:2147036])

HSP 1 Score: 450.669 bits (1158), Expect = 2.241e-133
Identity = 198/293 (67.58%), Postives = 239/293 (81.57%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L   Y++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRN+KFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  +H +LL+HMP EF   LDHI  L YF KPDY  + ++ + +M  +     + FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Mouse
Match: Ttbk2 (tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:2155779])

HSP 1 Score: 446.432 bits (1147), Expect = 2.214e-132
Identity = 199/290 (68.62%), Postives = 238/290 (82.07%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL KQ+LE IESIHSVGFLHRDIKPSNFAMGR PST RK +MLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL KQ+LE IESIHSVGFLHRDIKPSNFAMGR PST RK +MLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
Match: sp|Q5TCY1|TTBK1_HUMAN (Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TTBK1 PE=1 SV=2)

HSP 1 Score: 451.44 bits (1160), Expect = 1.080e-132
Identity = 198/293 (67.58%), Postives = 239/293 (81.57%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L   Y++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRN+KFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  +H +LL+HMP EF   LDHI  L YF KPDY  + ++ + +M  +     + FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
Match: sp|Q6PCN3|TTBK1_MOUSE (Tau-tubulin kinase 1 OS=Mus musculus OX=10090 GN=Ttbk1 PE=1 SV=3)

HSP 1 Score: 450.669 bits (1158), Expect = 1.568e-132
Identity = 198/293 (67.58%), Postives = 239/293 (81.57%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L   Y++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRN+KFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  +H +LL+HMP EF   LDHI  L YF KPDY  + ++ + +M  +     + FDWE
Sbjct:   19 EQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWE 311

[Close]

BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
Match: sp|Q3UVR3|TTBK2_MOUSE (Tau-tubulin kinase 2 OS=Mus musculus OX=10090 GN=Ttbk2 PE=1 SV=1)

HSP 1 Score: 446.432 bits (1147), Expect = 1.549e-131
Identity = 199/290 (68.62%), Postives = 238/290 (82.07%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL KQ+LE IESIHSVGFLHRDIKPSNFAMGR PST RK +MLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

[Close]

BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
Match: sp|Q6IQ55|TTBK2_HUMAN (Tau-tubulin kinase 2 OS=Homo sapiens OX=9606 GN=TTBK2 PE=1 SV=2)

HSP 1 Score: 446.047 bits (1146), Expect = 1.980e-131
Identity = 199/290 (68.62%), Postives = 238/290 (82.07%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L  G ++KERW+V +KIGGGGFG+IY+A+D+ ++E VALK+ESAQQ KQVLKMEVAVLKKLQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR+ S+G F+IS+ +RL +Q+LE IESIHSVGFLHRDIKPSNFAMGR PST RK YMLDFGLARQ+ N+ G+VRPPR VAGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG +K+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D ++       +DPFDWE
Sbjct:    9 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWE 298

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BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
Match: sp|Q8IMC6|ASATR_DROME (Tau-tubulin kinase homolog Asator OS=Drosophila melanogaster OX=7227 GN=Asator PE=1 SV=2)

HSP 1 Score: 444.121 bits (1141), Expect = 1.538e-130
Identity = 199/294 (67.69%), Postives = 239/294 (81.29%), Query Frame = 1

Query:  121 SSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            S DLL+PG+++KERW+V +KIGGGGFG+IYE  DL ++E+VALK+ESA+Q KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQGKNL ELRRA  +G FS+S+ +RL  Q+L+ IESIHSVGFLHRDIKPSNF++GRLP   R+VYMLDFGLARQY    GEVR PR  AGFRGTVRYAS NAH N+E+GRHDDLWSL Y+ VE V GQLPWRK+KDKEQVG  K+  DH +LL+H+P + KQ L+HIQ L Y  +PDY+ L  L ++ M R+  K +DP+DWE V
Sbjct:  159 SEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKV 452

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BLAST of Tau tubulin kinase 1a vs. TrEMBL
Match: A0A1S5XVZ9 (LPT OS=Schmidtea mediterranea OX=79327 GN=LPT PE=2 SV=1)

HSP 1 Score: 950.273 bits (2455), Expect = 0.000e+0
Identity = 616/643 (95.80%), Postives = 621/643 (96.58%), Query Frame = 3

Query: 2058 SLSPSTVPRMSSPVPLMQSSPHFQHQMTADYESGVQAAPFMPGKSITYPLTPGNREEIGGFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTSTDGINCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQXXXXXXXXXXXXXXXXXHDDPRAMNTIQSNSFAYRPLXXXXXXXXXXXXXXXXXXXXPSHLDDVIASVVSDSIAYIDESPATQSIALQRQNXXXXXXXXXXXXXXFDHDKXXXXXXXXXXXLMSGSGDPAAIESPLIAATQYQTAXXXXXXXXXXXXXXXXXXXFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAKQQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTPSSIELSPNM--SSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQNAIELGQSNKNQPESEKNSLIVQSADQVMXXXXXXXXXXXXXXXXXXXATMIKLNQHFSAGIQSMQSNNKAXXXXXXXXXXXXXXYSPGPTLHGAQNQQGVAMVXXXXXXXXXXXXTGSSLIMGPPVSNLRPNANVVTQRFICSINSNSTANTIPGQSPQQYLISSTPQSSASVGGAVCTAG 3980
            SLSPSTVP MSSPVPLMQSSPHFQHQMT DYESGV AAPFMPGKSIT PLTPGNREEIGGFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTS DGINCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQSSAGNNSRSFSRSNSVNHDDPRAMNTIQSNSFAYRPLSSANITNSNSTIVNINIQSQPSHLDDVIASVVSDSIAYIDESPATQSIALQRQN ++ SS   GGG GFDHDKS  AAAAVASSLM GSGDPAAIESPLIAATQYQTANNNNNNRSISRNLSSNQLIFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAKQQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTPSSIELSPNM  SSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQNAIELGQSNKNQ ESEKNSLIVQSADQVM +   +QQQQQQPSNSSSNATMIKLNQHFSAG+QSMQSNNKASSIQIPQISSNQFIYSPGPTLHGAQNQQGVAMVAQANNQLNAAAATGSSLIMGPPVSNLR NANVVTQRFICSINSNSTANTIPGQSPQQYLISSTPQSSASVGGAVCTAG
Sbjct: 2866 SLSPSTVPSMSSPVPLMQSSPHFQHQMTPDYESGVHAAPFMPGKSITCPLTPGNREEIGGFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTSNDGINCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQSSAGNNSRSFSRSNSVNHDDPRAMNTIQSNSFAYRPLSSANITNSNSTIVNINIQSQPSHLDDVIASVVSDSIAYIDESPATQSIALQRQN-SNDSSSCLGGGGGFDHDKSAVAAAAVASSLMPGSGDPAAIESPLIAATQYQTANNNNNNRSISRNLSSNQLIFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAKQQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTPSSIELSPNMSSSSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQNAIELGQSNKNQLESEKNSLIVQSADQVM-RQSPRQQQQQQPSNSSSNATMIKLNQHFSAGMQSMQSNNKASSIQIPQISSNQFIYSPGPTLHGAQNQQGVAMVAQANNQLNAAAATGSSLIMGPPVSNLRSNANVVTQRFICSINSNSTANTIPGQSPQQYLISSTPQSSASVGGAVCTAG 3506

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BLAST of Tau tubulin kinase 1a vs. TrEMBL
Match: A0A4U5U3D5 (Tau-tubulin kinase 1 OS=Collichthys lucidus OX=240159 GN=D9C73_001985 PE=4 SV=1)

HSP 1 Score: 451.055 bits (1159), Expect = 6.276e-142
Identity = 202/295 (68.47%), Postives = 244/295 (82.71%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            TS+ +D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH +LL+HMP EF   LDH+  L Y+ KPDY  L ++ + +M  ++    +PFDWE
Sbjct:    4 TSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWE 298

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BLAST of Tau tubulin kinase 1a vs. TrEMBL
Match: G3Q7K7 (Tau tubulin kinase 1a OS=Gasterosteus aculeatus OX=69293 PE=4 SV=1)

HSP 1 Score: 450.669 bits (1158), Expect = 7.907e-142
Identity = 202/295 (68.47%), Postives = 244/295 (82.71%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            TS+ +D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH +LL+HMP EF   LDH+  L Y+ KPDY  L ++ + +M  ++    +PFDWE
Sbjct:    4 TSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWE 298

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BLAST of Tau tubulin kinase 1a vs. TrEMBL
Match: A0A3P9CDN0 (Tau tubulin kinase 1a OS=Maylandia zebra OX=106582 PE=4 SV=1)

HSP 1 Score: 459.144 bits (1180), Expect = 3.744e-139
Identity = 204/295 (69.15%), Postives = 245/295 (83.05%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            TS+ +D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH LLL+HMP EFK  LDH+  L Y+ KPDY  L ++ + +M  ++    +PFDWE
Sbjct:   17 TSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERYDHQLLLKHMPSEFKIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWE 311

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BLAST of Tau tubulin kinase 1a vs. TrEMBL
Match: A0A3B4GI78 (Tau tubulin kinase 1a OS=Pundamilia nyererei OX=303518 PE=4 SV=1)

HSP 1 Score: 459.144 bits (1180), Expect = 3.744e-139
Identity = 204/295 (69.15%), Postives = 245/295 (83.05%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            TS+ +D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH LLL+HMP EFK  LDH+  L Y+ KPDY  L ++ + +M  ++    +PFDWE
Sbjct:   17 TSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERYDHQLLLKHMPSEFKIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWE 311

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BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
Match: ttbk1a (tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-100609-4])

HSP 1 Score: 448.358 bits (1152), Expect = 1.110e-138
Identity = 199/295 (67.46%), Postives = 242/295 (82.03%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            +S+  D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRNDKFNYVVM LQG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST RK YMLDFGLARQY NT+GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH +LL+HMP EF   LDH+  L Y+ KPDY  L ++ + +M  ++    + +DWE
Sbjct:   33 SSEQQDILPPNCMVKDRWKVLKKIGGGGFGEIYEAVDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILEAIEAIHSVGFLHRDIKPSNFAMGRLPSTVRKCYMLDFGLARQYTNTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQVKERYDHRMLLKHMPSEFHVFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENELYDWE 327

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BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
Match: ttbk1b (tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-100609-5])

HSP 1 Score: 445.277 bits (1144), Expect = 1.817e-137
Identity = 200/290 (68.97%), Postives = 240/290 (82.76%), Query Frame = 1

Query:  127 DLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D+L P  ++KERW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG +HVC+F GCGRN+KFNYVVM LQG+NL +LRR+  +G FS+S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT+GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  +H +LL+HMP EF   LDH+  L Y+ KPDY  L ++ + +M  +     +PFDWE
Sbjct:   22 DILPPNCMVKERWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHKMLLKHMPSEFYIFLDHVLGLDYYTKPDYLLLMSVFENSMKEREITENEPFDWE 311

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BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 426.787 bits (1096), Expect = 1.715e-128
Identity = 198/297 (66.67%), Postives = 236/297 (79.46%), Query Frame = 1

Query:  106 SPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            S  ++ +D+L  G +++ERWRV  KIGGGGFG+IYE +D  +Q  VALK+ESAQQ KQVLKMEVAVLK+LQ  DHVCRF GCGRND+FNYVVM LQG+NL +LRR  S+G FS+S+ +RL +Q+LE IESIHSVGFLHRDIKPSNFAMGRL ST R  YMLDFGLARQ+ N+  EVRPPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRKVKDKEQVG LK+  DH+L+L+H+P EF   L+HI  L YF KPDY  L ++ +++M        DP+DWE
Sbjct:    2 SGAAEQADILSVGNVVRERWRV--KIGGGGFGEIYEVLDQLNQCNVALKVESAQQPKQVLKMEVAVLKRLQK-DHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSQGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIKPSNFAMGRLSSTCRTCYMLDFGLARQFTNSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKVKDKEQVGNLKETYDHHLMLKHLPSEFIVFLEHISNLDYFTKPDYQLLMSVFEKSMKSYNVMENDPYDWE 295

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BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
Match: ttbk2b (tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-030131-8246])

HSP 1 Score: 348.206 bits (892), Expect = 1.451e-106
Identity = 174/297 (58.59%), Postives = 210/297 (70.71%), Query Frame = 1

Query:  106 SPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            S  ++ +D+L  G +++ERWRV KKIGGGGFG+IYE +D  +Q  VALK+ESAQQ KQVLKMEVAVLK+LQG DHVCRF GCGRND+FNYVVM LQG+NL +LRR  S+G FS+S+ +RL +Q+LE IESIHSVGFLHRDIK                                   PPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRKVKDKEQVG LK+  DH+L+L+H+P EF   L+HI  L YF KPDY  L ++ +++M        DP+DWE
Sbjct:    2 SGAAEQADILSVGNVVRERWRVIKKIGGGGFGEIYEVLDQLNQCNVALKVESAQQPKQVLKMEVAVLKRLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSQGTFSVSTTLRLGRQILEAIESIHSVGFLHRDIK-----------------------------------PPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKVKDKEQVGNLKETYDHHLMLKHLPSEFIVFLEHISNLDYFTKPDYQLLMSVFEKSMKSYNVMENDPYDWE 263

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BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
Match: csnk1db (casein kinase I [Source:NCBI gene;Acc:103030301])

HSP 1 Score: 173.326 bits (438), Expect = 2.903e-47
Identity = 109/307 (35.50%), Postives = 158/307 (51.47%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEV 1050
            +  R+R+ +KIG G FG IY   D+S  E+VA+KLE  +     L +E  + K +QG   +     CG    +N +VM L G +L +L    S+  FS+ +++ L  QM+  IE IHS  F+HRD+KP NF MG L      VY++DFGLA++Y +       P R      GT RYAS N H   E  R DDL SL Y+ +    G LPW+ +K        E++ + K +    +L +  P EF   L+  + L +  KPDYS L+ L      R+ F +   FDW ++  + P  TN    + V
Sbjct:    5 VGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRK-FSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML--KFPQITNCPGALGV 307

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BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004926.1 (pep scaffold:Pmarinus_7.0:GL480178:196:11423:1 gene:ENSPMAG00000004461.1 transcript:ENSPMAT00000004926.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 333.954 bits (855), Expect = 7.013e-105
Identity = 148/224 (66.07%), Postives = 174/224 (77.68%), Query Frame = 1

Query:  325 DHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            DHVCRF GCGRNDKFNYVVM LQG+NL +LRR+  +G FS+S+ +RL +QMLE IESIH+VGFLHRDIKPSNFAMGRLPST  K +MLD+GLARQY N+ GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG +K+  DH LLLRHMP +F   LDH+  L Y  +P+Y  + +     M  +     +P+DWE
Sbjct:    2 DHVCRFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSLSTTLRLGRQMLEAIESIHAVGFLHRDIKPSNFAMGRLPSTTHKCFMLDYGLARQYTNSSGEVRPPRAVAGFRGTVRYASINAHRNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGLIKERYDHRLLLRHMPTDFHIFLDHVSTLDYCTRPNYQSIHSCALHIMRERSITENEPYDWE 225

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BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008477.1 (pep scaffold:Pmarinus_7.0:GL482342:316:9736:-1 gene:ENSPMAG00000007664.1 transcript:ENSPMAT00000008477.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 162.925 bits (411), Expect = 6.204e-44
Identity = 102/289 (35.29%), Postives = 151/289 (52.25%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIY-EAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDW 993
            I  ++R+ +KIG G FG IY    ++++ E+VA+KLE  +     L +E  + K LQG   +     CG    +N +VM L G ++ +L    S+  FS+ +++ L  QM+  IE +HS  F+HRDIKP NF MG L      VY++D GLA++Y ++      P R      GT RYAS N H   E  R DDL SL Y+ +    G LPW+ +K        E++ + K +    +L +  P EF   L+  + L +  KPDYS L+ L      R+ F +   FDW
Sbjct:    5 IGNKYRLGRKIGSGSFGDIYLVGTNIATGEEVAIKLECVKTKHPQLHIESKIYKLLQGGVGIPVIKWCGAEGDYNVMVMELLGPSMEDLFNFCSRK-FSLKTVLLLADQMISRIEYLHSKNFIHRDIKPDNFLMG-LGKKGNLVYIIDLGLAKKYRDSRTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEMLCKTYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDW 291

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BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
Match: csnk1g2a (casein kinase 1, gamma 2a [Source:ZFIN;Acc:ZDB-GENE-030131-6445])

HSP 1 Score: 155.992 bits (393), Expect = 6.780e-41
Identity = 90/290 (31.03%), Postives = 156/290 (53.79%), Query Frame = 1

Query:  148 IIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRK-VYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDW 993
            ++   +RV KKIG G FG++    +L + E VA+KLE  +     L +E    K+L   + V + Y  G   K+N +V+ L G +L +L    ++  F++ +++ +  Q+L  +E +HS   ++RD+KP NF +GR  +  +  ++++DFGLA++Y++ + +   P R      GT RY S N H  KE  R DDL +L ++ +  + G LPW+ +K        +++G  K+     +L  + P E    L +++ L +F +PDY  ++NL      RK + F   FDW
Sbjct:   33 MVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGNAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCNR-TFTLKTVLMIAIQLLTRMEYVHSRNLIYRDVKPENFLIGRQSTNKQHIIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENFPEEMATYLRYVRRLDFFERPDYEYMRNLFMDLFERKGYSFDYEFDW 321

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BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
Match: csnk1g1 (casein kinase 1, gamma 1 [Source:NCBI gene;Acc:494092])

HSP 1 Score: 125.561 bits (314), Expect = 2.616e-32
Identity = 77/238 (32.35%), Postives = 128/238 (53.78%), Query Frame = 1

Query:   88 NDLSMPSPTSDSSDLLEPGYI-IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRL-PSTFRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVK 792
              +S   P+S  S     G + +   +RV KKIG G FG++    +L + E VA+KLE  +     L +E    K+L   + V + Y  G   K+N +V+ L G +L +L     +  FS+ +++ +  Q++  +E +HS   ++RD+KP NF +GR   S    ++++DFGLA++Y++ + +   P R      GT RY S N H  KE  R DDL +L ++ +  + G LPW+ +K
Sbjct:    6 TSVSRGGPSSRGSGAPSSGVLMVGPNFRVGKKIGCGNFGELRLGKNLYTNEYVAIKLEPMKSRAPQLHLEYRFYKQLGNAEGVPQVYYFGPCGKYNAMVLELLGPSLEDLFDLCDR-TFSLKTVLMIAMQLISRMEYVHSRSLIYRDVKPENFLVGRQGTSKHHNIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLK 242

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BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001691.1 (pep scaffold:Pmarinus_7.0:GL476581:539457:546336:1 gene:ENSPMAG00000001522.1 transcript:ENSPMAT00000001691.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 119.783 bits (299), Expect = 9.113e-31
Identity = 76/194 (39.18%), Postives = 115/194 (59.28%), Query Frame = 1

Query:  145 YIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQ---GLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVR---PPRPVAGFRGTVRYASANAHFNKE 708
            +I+  ++R+ +KIG G FG IY AI++++ E+VA+KLES +     L  E  + K LQ   G+ H+ R+Y  G+   +N +VM L G +L +L    S+  F++ +++ L  QM+  IE +H+  F+HRDIKP NF MG +     K++++DFGLA++Y   D   R   P R      GT RYAS NAH   E
Sbjct:   11 FIVGGKYRLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPHI-RWY--GQEKDYNVLVMDLLGPSLEDLFNFCSRR-FTMKTVLMLADQMISRIEYVHNKNFIHRDIKPDNFLMG-IGRHCNKLFLIDFGLAKKY--RDNRTRQHIPYREDKNLTGTARYASINAHLGIE 197

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BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
Match: HRR25 (Conserved casein kinase; regulates diverse events including: vesicular traffic, DNA repair, the CVT pathway, monopolar attachment of sister kinetochores at meiosis I, and ribosomal subunit biogenesis; monopolin subunit; binds the RNAPII CTD; phosphorylates COPII coat subunits; interacts with Sit4p phosphatase; antagonizes calcineurin signaling, reducing nuclear accumulation of Crz1p; phosphorylates Dsn1p, the kinetochore receptor for monopolin; homolog of mammalian CK1delta [Source:SGD;Acc:S000006125])

HSP 1 Score: 157.532 bits (397), Expect = 5.973e-41
Identity = 102/294 (34.69%), Postives = 151/294 (51.36%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMG--RLPSTFRKVYMLDFGLARQY--VNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            +  ++R+ +KIG G FG IY   +L S E+VA+KLES +     L  E  V + L G   +      GR  ++N +V+ L G +L +L     +  FS  +++ L  QM   I+ IH   F+HRDIKP NF MG  R  ST   V+++DFGL+++Y   NT   + P R      GT RYAS N H   E  R DDL SL Y+ +    G LPW+ +K        +++ + K NV    L   +PLEF++ + + + L +  KPDY  L  L      +  +     FDW ++
Sbjct:    5 VGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIRWFGREGEYNAMVIDLLGPSLEDLFNYCHRR-FSFKTVIMLALQMFCRIQYIHGRSFIHRDIKPDNFLMGVGRRGST---VHVIDFGLSKKYRDFNTHRHI-PYRENKSLTGTARYASVNTHLGIEQSRRDDLESLGYVLIYFCKGSLPWQGLKATTKKQKYDRIMEKKLNVSVETLCSGLPLEFQEYMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTML 293

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BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
Match: YCK2 (Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK2 has a paralog, YCK1, that arose from the whole genome duplication [Source:SGD;Acc:S000005098])

HSP 1 Score: 139.428 bits (350), Expect = 1.046e-34
Identity = 88/308 (28.57%), Postives = 156/308 (50.65%), Query Frame = 1

Query:  148 IIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPST-FRKVYMLDFGLARQYVNTDGEVR-PPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTM---------ARKLFKFTDPFDWEIVVHQEPN 1020
            I+   +++ KKIG G FG ++E  ++ +   VA+K E  +     LK E    K L G   + + Y  G+    N +V+ L G +L +L     +  FS+ ++V++  QM+  IE +H+   ++RDIKP NF +GR       KV+++DFG+A+QY +   +   P R      GT RY S N H  +E  R DD+ ++ ++    + GQLPW+ +K        E++G+ K+  +   L + +P++F + L+ ++ L +   PDY   + LL   +              K      W++ ++++PN
Sbjct:   71 IVGLHYKIGKKIGEGSFGVLFEGTNMINGLPVAIKFEPRKTEAPQLKDEYRTYKILAGTPGIPQEYYFGQEGLHNILVIDLLGPSLEDLFDWCGR-RFSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANKVHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEAMGHVFFYFLRGQLPWQGLKAPNNKQKYEKIGEKKRLTNVYDLAQGLPIQFGRYLEIVRNLSFEETPDYEGYRMLLLSVLDDLGETADGQYDWMKLNGGRGWDLSINKKPN 377

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
Match: YCK1 (Palmitoylated plasma membrane-bound casein kinase I (CK1) isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking, and glucose sensing; stabilized by Sod1p binding in the presence of glucose and oxygen, causing glucose repression of respiratory metabolism; involved in the phosphorylation and regulation of glucose sensor Rgt2p; YCK1 has a paralog, YCK2, that arose from the whole genome duplication [Source:SGD;Acc:S000001177])

HSP 1 Score: 138.272 bits (347), Expect = 2.558e-34
Identity = 86/308 (27.92%), Postives = 156/308 (50.65%), Query Frame = 1

Query:  148 IIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPST-FRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTM---------ARKLFKFTDPFDWEIVVHQEPN 1020
            I+   +++ KKIG G FG ++E  ++ +   VA+K E  +     L+ E    K L G  ++   Y  G+    N +V+ L G +L +L     +  FS+ ++V++  QM+  IE +H+   ++RDIKP NF +GR        ++++DFG+A+QY +   +   P R      GT RY S N H  +E  R DD+ +L ++    + G LPW+ +K        E++G+ K++ +   L + +P++F + L+ ++ L +   PDY   + LL   +              K  D   W++ ++++PN
Sbjct:   64 IVGLHYKIGKKIGEGSFGVLFEGTNMINGVPVAIKFEPRKTEAPQLRDEYKTYKILNGTPNIPYAYYFGQEGLHNILVIDLLGPSLEDLFDWCGRK-FSVKTVVQVAVQMITLIEDLHAHDLIYRDIKPDNFLIGRPGQPDANNIHLIDFGMAKQYRDPKTKQHIPYREKKSLSGTARYMSINTHLGREQSRRDDMEALGHVFFYFLRGHLPWQGLKAPNNKQKYEKIGEKKRSTNVYDLAQGLPVQFGRYLEIVRSLSFEECPDYEGYRKLLLSVLDDLGETADGQYDWMKLNDGRGWDLNINKKPN 370

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
Match: YCK3 (Palmitoylated vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway [Source:SGD;Acc:S000000925])

HSP 1 Score: 129.413 bits (324), Expect = 1.683e-31
Identity = 92/326 (28.22%), Postives = 146/326 (44.79%), Query Frame = 1

Query:  145 YIIKERWRVNKKIGGGGFGQIYEAIDL-----------------SSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAM---------GRLPSTFRK--------VYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQ--NVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDW 993
            +I+   + V  KIG G FG I+E  ++                  + E VA+K E        L+ E    + L G   +   Y  G+    N +++ L G +L +L     +  FS+ +   + KQM++ + +IH    ++RDIKP NF +         G++  +           +YM+DFG+A+QY +   +   P R      GT RY S N HF +E  R DDL SL ++    + G LPW+ +K        E++G  KQ  N D  LL   +P +F   L + + L +   PDY  L +L+D  +     K    +DW
Sbjct:    8 HIVGIHYAVGPKIGEGSFGVIFEGENILHSCQAQTGSKRDSSIIMANEPVAIKFEPRHSDAPQLRDEFRAYRILNGCVGIPHAYYFGQEGMHNILIIDLLGPSLEDLFEWCGRK-FSVKTTCMVAKQMIDRVRAIHDHDLIYRDIKPDNFLISQYQRISPEGKVIKSCASSSNNDPNLIYMVDFGMAKQYRDPRTKQHIPYRERKSLSGTARYMSINTHFGREQSRRDDLESLGHVFFYFLRGSLPWQGLKAPNNKLKYEKIGMTKQKLNPDDLLLNNAIPYQFATYLKYARSLKFDEDPDYDYLISLMDDALRLNDLKDDGHYDW 332

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
Match: SSK2 (MAP kinase kinase kinase of HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress; a HOG-independent function of Ssk2p mediates the calcium-sensitive phenotype of the ptp2 msg5 double disruptant; SSK2 has a paralog, SSK22, that arose from the whole genome duplication [Source:SGD;Acc:S000005314])

HSP 1 Score: 79.7221 bits (195), Expect = 3.498e-15
Identity = 71/251 (28.29%), Postives = 114/251 (45.42%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQ------VLKMEVAVLKKLQGLDHVCRFYGCG-RNDKFNYVVMSLQGKNLGELR---RATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVY-MLDFGLARQYVN-------------TDGE------VRPPRPVAG-------FRGTVRYAS----ANAHFNKELGRHDDLWSLLYLAVEMVTGQLPW 780
            +  RW+    IGGG FG++Y A+DL + E +A+K  + Q SK       ++K E++VL+ L    ++  +YG     DK N  +   +G +L  L    R   + +  + ++     Q+LE +  +H  G +HRD+KP N  +      F  V   +DFG A++  N              DGE      V   + V           GT  Y +      +    +LG  DD+WSL  + +EM+TG+ PW
Sbjct: 1262 VSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMSVLEILNH-PNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTL-----QLLEGLAYLHESGIVHRDVKPENILLD-----FNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAVKNNENALLDMMGTPMYMAPESITGSTTKGKLGA-DDVWSLGCVVLEMITGRRPW 1500

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BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
Match: EDO46789 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RP40])

HSP 1 Score: 389.423 bits (999), Expect = 1.408e-123
Identity = 187/291 (64.26%), Postives = 228/291 (78.35%), Query Frame = 1

Query:  124 SDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            +DLL+PG ++++RW++ KKIGGGGFG+IY  +D  +++ VA+KLES  QSKQVLKMEVAVLKKLQG+DH+C+F  CGRN+ FNY+VMSLQG NL ELRR+  KG+FS S+M+RL  Q+L+ ++SIH  GFLHRDIKPSNFAMG  P T    YMLDFGL+RQ+   +GEVRPPR  AGFRGTVRYAS NAH NKE+GRHDDLWS  YL VE   GQLPWRK+KDKEQVGK+K+  D   LL+ MP EFKQ +DHI +L Y  KPDY  L  LL+Q + RK  K +DP+DWE
Sbjct:    2 ADLLKPGDVVRQRWKIIKKIGGGGFGEIYRGLDQVTKDYVAIKLESVHQSKQVLKMEVAVLKKLQGVDHICKFISCGRNESFNYLVMSLQGSNLAELRRSQPKGVFSHSTMLRLGTQILKSVKSIHEAGFLHRDIKPSNFAMGNTPDTVHICYMLDFGLSRQFTKANGEVRPPRNTAGFRGTVRYASINAHENKEMGRHDDLWSFFYLMVEFTVGQLPWRKMKDKEQVGKMKKTYDIANLLKSMPGEFKQFVDHISKLKYEDKPDYKMLLGLLEQIIKRKGIKESDPYDWE 292

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
Match: EDO34742 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNG2])

HSP 1 Score: 166.777 bits (421), Expect = 1.689e-44
Identity = 101/291 (34.71%), Postives = 151/291 (51.89%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            +  ++R+ +KIG G FG IY    +S+ E+VA+KLE  +     L +E    K +QG   +     CG    +N +VM L G +L +L    ++  FSI +++ L  Q +  IE +HS  F+HRDIKP NF MG L      VY++DFGLA++Y +       P R      GT RYAS N H   E  R DDL SL Y+ +    G LPW+ +K        E++ + K +    +L +  P EF   L++ + L +  KPDYS L+ L      R+ + +   FDW ++
Sbjct:    5 VGNKYRLGRKIGSGSFGDIYLGTSISTGEEVAIKLECVKTKHPQLHIEAKFYKMMQGGVGIPTIKWCGTEGDYNVLVMELLGPSLEDLFNFCNRK-FSIKTVLLLADQTISRIEYVHSKNFIHRDIKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDPRTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGFPSEFATYLNNCRSLRFDDKPDYSYLRQLFRNLFHRQGYTYDYVFDWNLL 293

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
Match: EDO46523 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPJ6])

HSP 1 Score: 156.377 bits (394), Expect = 1.851e-41
Identity = 104/304 (34.21%), Postives = 165/304 (54.28%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHV--CRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVR---PPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKL-FKFTDPFDWEIVVHQEPNST 1026
            +  ++R+ +KIG G FG IY AI+ ++ E+VA+KLES +     L  E  + K LQG   +   R+YG  R+  +N +VM L G +L +L    S+  F++ +++ L  QM+  IE +H+  F+HRDIKP NF MG +     K++++DFGLA++Y   D   R   P R      GT RYAS NAH   E  R DD+ SL Y+ +      LPW+ +K        E++ + K +    +L +  P EF   L++ + L +   PDY  L+ L  + + R L +++   FDW ++  +   +T
Sbjct:   15 VGGKYRLVRKIGSGSFGDIYLAINTTNGEEVAVKLESQKARHPQLLYESKLYKILQGGVGIPSVRYYGQERD--YNVLVMELLGPSLEDLFNFCSRR-FTMKTVLMLADQMISRIEYVHNKNFIHRDIKPDNFLMG-VGKHCNKLFLIDFGLAKKY--RDSRTRQHIPYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLF-RILFRTLNYQYDYIFDWTMLKQKAAQAT 311

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
Match: EDO34289 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPP6])

HSP 1 Score: 152.14 bits (383), Expect = 4.768e-39
Identity = 96/293 (32.76%), Postives = 154/293 (52.56%), Query Frame = 1

Query:  148 IIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKL---QGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRK-VYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDW 993
            ++   +RV KKIG G FG++    +L + E VA+KLE  +     L +E    K L   +G+  V  F  CG   K+N +VM L G +L +L    ++  FS+ +++ +  Q++  IE +HS   ++RDIKP NF +GR  +   K + ++DFGLA++Y++ + +   P R      GT RY S N H  KE  R DDL +L ++ +  + G LPW+ +K        +++G  K+     +L  + P E    L +++ L +F  PDY  L+ L    M RK +     FDW
Sbjct:   41 MVGPNFRVGKKIGCGNFGELRLGKNLYNNEHVAIKLEPMKSRAPQLHLEYRFYKALGNAEGIPQVHYFGPCG---KYNALVMELLGPSLEDLFDLCNRQ-FSLKTVLMVALQLISRIEYVHSKNMIYRDIKPENFLIGRKSAGKEKTINIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHMFMYFLRGSLPWQGLKADTLKERYQKIGDTKRATPIEVLCENHPEEMATYLRYVRRLDFFETPDYEYLRKLFRDLMERKGYVEDFEFDW 329

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BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
Match: EDO48738 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIM1])

HSP 1 Score: 141.739 bits (356), Expect = 1.442e-36
Identity = 96/309 (31.07%), Postives = 159/309 (51.46%), Query Frame = 1

Query:  100 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKL-FKFTDPFDWEIV 1002
            M +P S+        +I++ ++R+ +KIG G FG IY  +   + E+ A+KLES +     L  E  + K L G   +       + + +N +VM L G +L +L    ++  F++ +++ L  QM+  IE +H+  F+HRDIKP NF MG +     K+Y++DFGLA++Y ++  +     R      GT RYAS NAH   E  R DD+ SL Y+ +      LPW+ +K        E++ + K +    +L +  P EF   L++ + L +   PDY  L+ L  + + R L  ++   FDW  +
Sbjct:    1 MSTPKSE--------FIVQGKYRLVRKIGSGSFGDIYLCVHTENGEEKAVKLESQKARHPQLLYESKLYKILAGGSGIPAIRHFSQENDYNVLVMDLLGPSLEDLFNFCNRK-FNMKTVLMLADQMIARIEYVHNKNFIHRDIKPDNFLMG-IGRHCNKLYLIDFGLAKKYRDSRTKQHISYREDKNLTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRSNLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFSMYLNYCKGLRFEEAPDYMYLRQLF-RILFRTLNHQYDYIFDWTTL 298

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BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
Match: ttbk2a (tau tubulin kinase 2 [Source:NCBI gene;Acc:101174145])

HSP 1 Score: 428.713 bits (1101), Expect = 5.554e-127
Identity = 199/295 (67.46%), Postives = 234/295 (79.32%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQ-GKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKP-SNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L    ++KERW+V +KIGGGGFG+IYEA+DL ++  VALK+ESAQQ KQVLKMEVAVLKKLQ  DH+CRF GCGRND+FNYVVM LQ G+NL +LRR+  +G FSIS+ +RL  Q+LE IESIHSVGFLHRDIKP SNFAMGR PST R  YMLDFGLARQ+ N+  EVRPPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRK+K+KEQVGKLK+  DH L+LRH+P EF   LDHI  L YF KPDY  L ++ D +M        DP+DWE
Sbjct:    6 EPADILSVLSLVKERWKVVRKIGGGGFGEIYEAMDLLTRASVALKVESAQQPKQVLKMEVAVLKKLQK-DHICRFVGCGRNDRFNYVVMELQQGRNLADLRRSMPRGTFSISTTLRLGHQILEAIESIHSVGFLHRDIKPQSNFAMGRFPSTCRTCYMLDFGLARQFTNSCQEVRPPRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKEKEQVGKLKETYDHCLMLRHLPAEFGVFLDHISNLDYFTKPDYQLLMSVFDNSMKTYNVVENDPYDWE 299

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BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
Match: ttbk1a (tau tubulin kinase 1 [Source:NCBI gene;Acc:105354132])

HSP 1 Score: 409.453 bits (1051), Expect = 1.806e-124
Identity = 190/302 (62.91%), Postives = 233/302 (77.15%), Query Frame = 1

Query:  112 TSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGL-------DHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            TS+ +D+L P  ++K+RW+V KKIGGGGFG+IYEA+DL ++E VALK+ESAQQ KQVLKMEVAVLKKLQG        D V  F G    +K  + V   QG+NL +LRR+  +G F++S+ +RL KQ+LE IE+IHSVGFLHRDIKPSNFAMGRLPST+RK YMLDFGLARQY NT+GEVRPPR VAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE   GQLPWRK+KDKEQVG++K+  DH +LL+HMP EF   LDH+  L Y+ KPDY  L ++ + +M  ++    +PFDWE
Sbjct:   17 TSEQADILPPNCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGETLLHEHEDPVVSFLG----NKLFFFVWLAQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGQIKERFDHKMLLKHMPSEFSIFLDHVLALDYYTKPDYQLLMSVFENSMKERIITENEPFDWE 314

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BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
Match: ttbk2b (tau-tubulin kinase 2 [Source:NCBI gene;Acc:101157747])

HSP 1 Score: 368.237 bits (944), Expect = 1.207e-113
Identity = 174/293 (59.39%), Postives = 205/293 (69.97%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            D +D+L  G ++++RW+V +KIGGGGFG+IYE +D  SQ  VALK+ESAQQ KQVLKMEVAVLKKLQG +HVCRF GCGRND+FNYVVM LQG+NL +LRR  S+G FS+S+ +RL KQ+LE IESIHSVGFLHRDIK                                   PPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRK+KDKEQVG LK+  DH L+L+H+P EF   LDHI  L YF KPDY  L ++ D  M        DP+DWE
Sbjct:    6 DHTDILTVGDVVRDRWKVIRKIGGGGFGEIYEVLDQLSQATVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCRFVGCGRNDRFNYVVMELQGRNLADLRRTMSRGTFSVSTTLRLGKQILEAIESIHSVGFLHRDIK-----------------------------------PPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFMVGQLPWRKIKDKEQVGNLKETYDHRLMLKHLPSEFSTFLDHIMTLDYFTKPDYQLLTSMFDSAMKSHNVLENDPYDWE 263

[Close]

BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
Match: ttbk2a (tau tubulin kinase 2 [Source:NCBI gene;Acc:101174145])

HSP 1 Score: 365.155 bits (936), Expect = 1.801e-112
Identity = 174/293 (59.39%), Postives = 207/293 (70.65%), Query Frame = 1

Query:  118 DSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWE 996
            + +D+L    ++KERW+V +KIGGGGFG+IYEA+DL ++  VALK+ESAQQ KQVLKMEVAVLKKLQG DH+CRF GCGRND+FNYVVM LQG+NL +LRR+  +G FSIS+ +RL  Q+LE IESIHSVGFLHRDIK                                   PPRPVAGFRGTVRYAS NAH NKE+GRHDDLWSL Y+ VE + GQLPWRK+K+KEQVGKLK+  DH L+LRH+P EF   LDHI  L YF KPDY  L ++ D +M        DP+DWE
Sbjct:    6 EPADILSVLSLVKERWKVVRKIGGGGFGEIYEAMDLLTRASVALKVESAQQPKQVLKMEVAVLKKLQGKDHICRFVGCGRNDRFNYVVMELQGRNLADLRRSMPRGTFSISTTLRLGHQILEAIESIHSVGFLHRDIK-----------------------------------PPRPVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKEKEQVGKLKETYDHCLMLRHLPAEFGVFLDHISNLDYFTKPDYQLLMSVFDNSMKTYNVVENDPYDWE 263

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BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
Match: csnk1db (casein kinase 1 delta [Source:NCBI gene;Acc:101156740])

HSP 1 Score: 173.711 bits (439), Expect = 2.258e-46
Identity = 105/291 (36.08%), Postives = 152/291 (52.23%), Query Frame = 1

Query:  151 IKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPP-RPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDK------EQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIV 1002
            +  R+R+ +KIG G FG IY   D+S  E+VA+KLE  +     L +E  + K +QG   +     CG    +N +VM L G +L +L    S+  FS+ +++ L  QM+  IE IHS  F+HRD+KP NF MG L      VY++DFGLA++Y +       P R      GT RYAS N H   E  R DDL SL Y+ +    G LPW+ +K        E++ + K +    +L +  P EF   L+  + L +  KPDYS L+ L      R+ F +   FDW ++
Sbjct:    5 VGNRYRLGRKIGSGSFGDIYLGTDISVGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPIIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRK-FSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMG-LGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNML 293

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BLAST of Tau tubulin kinase 1a vs. Planmine SMEST
Match: SMESG000068893.1 (SMESG000068893.1)

HSP 1 Score: 1311.98 bits (3394), Expect = 0.000e+0
Identity = 641/645 (99.38%), Postives = 643/645 (99.69%), Query Frame = 1

Query:  100 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNNENSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVSDQMHKLDLKSDFSKMKSDTNNKFANIKSPNVARNNSTKPILSIANLKSSCNNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTISDENIIFHRSSSLDHSAPSVRGIMKGLSNNNFCSTSQPFQTDSVLSIPDIHKVASVDDHYFLRSXXXXXXXXXXXRYQAIYIHPESVLSDKYRFSHIPDAIICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTYISNVMC 2034
            MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNN+NSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVSDQMHKLDLKSDFSK+KSDTNNKFANIKSPNVARNNSTKPILSIANLKSSCNNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTISDENIIFHRSSSLDHSAP VRGIMKGLSNNNFCSTSQPFQTDSVLSIPDIHKVASVDDHYFLRSNDNDVDDGDNDRYQAIYIHPESVLSDKYRFSHIPDAIICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTY SNVMC
Sbjct:    1 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNNDNSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVSDQMHKLDLKSDFSKIKSDTNNKFANIKSPNVARNNSTKPILSIANLKSSCNNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTISDENIIFHRSSSLDHSAPPVRGIMKGLSNNNFCSTSQPFQTDSVLSIPDIHKVASVDDHYFLRSNDNDVDDGDNDRYQAIYIHPESVLSDKYRFSHIPDAIICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTYTSNVMC 645

[Close]

BLAST of Tau tubulin kinase 1a vs. Planmine SMEST
Match: SMESG000068893.1 (SMESG000068893.1)

HSP 1 Score: 1167.53 bits (3019), Expect = 0.000e+0
Identity = 592/645 (91.78%), Postives = 597/645 (92.56%), Query Frame = 1

Query:  100 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNNENSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVSDQMHKLDLKSDFSKMKSDTNNKFANIKSPNVARNNSTKPILSIANLKSSCNNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTISDENIIFHRSSSLDHSAPSVRGIMKGLSNNNFCSTSQPFQTDSVLSIPDIHKVASVDDHYFLRSXXXXXXXXXXXRYQAIYIHPESVLSDKYRFSHIPDAIICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTYISNVMC 2034
            MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSM         CIE I S   L  D  P +F                     +Y+      RPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNN+NSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVSDQMHKLDLKSDFSK+KSDTNNKFANIKSPNVARNNSTKPILSIANLKSSCNNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTISDENIIFHRSSSLDHSAP VRGIMKGLSNNNFCSTSQPFQTDSVLSIPDIHKVASVDDHYFLRSNDNDVDDGDNDRYQAIYIHPESVLSDKYRFSHIPDAIICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTY SNVMC
Sbjct:    1 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMDF-------CIE-ILSPQILLWDGCPVHF--------------------EKYI-----FRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQKENNNDNSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVSDQMHKLDLKSDFSKIKSDTNNKFANIKSPNVARNNSTKPILSIANLKSSCNNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTISDENIIFHRSSSLDHSAPPVRGIMKGLSNNNFCSTSQPFQTDSVLSIPDIHKVASVDDHYFLRSNDNDVDDGDNDRYQAIYIHPESVLSDKYRFSHIPDAIICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTYTSNVMC 612

[Close]

BLAST of Tau tubulin kinase 1a vs. Planmine SMEST
Match: SMESG000040592.1 (SMESG000040592.1)

HSP 1 Score: 949.118 bits (2452), Expect = 0.000e+0
Identity = 616/643 (95.80%), Postives = 621/643 (96.58%), Query Frame = 3

Query: 2058 SLSPSTVPRMSSPVPLMQSSPHFQHQMTADYESGVQAAPFMPGKSITYPLTPGNREEIGGFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTSTDGINCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQXXXXXXXXXXXXXXXXXHDDPRAMNTIQSNSFAYRPLXXXXXXXXXXXXXXXXXXXXPSHLDDVIASVVSDSIAYIDESPATQSIALQRQNXXXXXXXXXXXXXXFDHDKXXXXXXXXXXXLMSGSGDPAAIESPLIAATQYQTAXXXXXXXXXXXXXXXXXXXFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAKQQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTPSSIELSPNM--SSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQNAIELGQSNKNQPESEKNSLIVQSADQVMXXXXXXXXXXXXXXXXXXXATMIKLNQHFSAGIQSMQSNNKAXXXXXXXXXXXXXXYSPGPTLHGAQNQQGVAMVXXXXXXXXXXXXTGSSLIMGPPVSNLRPNANVVTQRFICSINSNSTANTIPGQSPQQYLISSTPQSSASVGGAVCTAG 3980
            SLSPSTVP MSSPVPLMQSSPHFQHQMT DYESGV AAPFMPGKSIT PLTPGNREEIGGFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTS DGINCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQSSAGNNSRSFSRSNSVNHDDPRAMNTIQSNSFAYRPLSSANITNSNSTIVNINIQSQPSHLDDVIASVVSDSIAYIDESPATQSIALQRQN ++ SS   GGG GFDHDKS  AAAAVASSLM GSGDPAAIESPLIAATQYQTANNNNNNRSISRNLSSNQLIFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAKQQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTPSSIELSPNM  SSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQNAIELGQSNKNQ ESEKNSLIVQSADQVM +   +QQQQQQPSNSSSNATMIKLNQHFSAG+QSMQSNNKASSIQIPQISSNQFIYSPGPTLHGAQNQQGVAMVAQANNQLNAAAATGSSLIMGPPVSNLR NANVVTQRFICSINSNSTANTIPGQSPQQYLISSTPQSSASVGGAVCTAG
Sbjct: 2848 SLSPSTVPSMSSPVPLMQSSPHFQHQMTPDYESGVHAAPFMPGKSITCPLTPGNREEIGGFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTSNDGINCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQSSAGNNSRSFSRSNSVNHDDPRAMNTIQSNSFAYRPLSSANITNSNSTIVNINIQSQPSHLDDVIASVVSDSIAYIDESPATQSIALQRQN-SNDSSSCLGGGGGFDHDKSAVAAAAVASSLMPGSGDPAAIESPLIAATQYQTANNNNNNRSISRNLSSNQLIFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAKQQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTPSSIELSPNMSSSSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQNAIELGQSNKNQLESEKNSLIVQSADQVM-RQSPRQQQQQQPSNSSSNATMIKLNQHFSAGMQSMQSNNKASSIQIPQISSNQFIYSPGPTLHGAQNQQGVAMVAQANNQLNAAAATGSSLIMGPPVSNLRSNANVVTQRFICSINSNSTANTIPGQSPQQYLISSTPQSSASVGGAVCTAG 3488

[Close]

BLAST of Tau tubulin kinase 1a vs. Planmine SMEST
Match: SMESG000048011.1 (SMESG000048011.1)

HSP 1 Score: 461.455 bits (1186), Expect = 6.529e-147
Identity = 216/339 (63.72%), Postives = 267/339 (78.76%), Query Frame = 1

Query:  115 SDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQ 1131
            SDSSDLL+ G ++K+RWRV +KIGGGGFG+IYEA D ++Q++VALKLES++Q KQVLKMEVAVLKK+QG +H CRF GCGRND+FNY+VMSLQG+NL ELRR T +GIFS+S+M++L +Q+L+ IE+IH VGFLHRD+KPSNFAMGRLP T R VY+LDFGL+RQY+N D EVR PRP+AGFRGTVRYAS NAH N+E+GRHDDLWS+ Y+ VEMVTGQLPWRK+KDKEQVG++KQ+ DH +LLRH+P EF+  L+H+Q L YF  PDY+ L+NL D+ M RK    +D FDWE        STN+  EVE+           N+  Y  G  RP  SQ
Sbjct:    5 SDSSDLLQAGNVVKDRWRVIRKIGGGGFGEIYEAFDEATQDRVALKLESSRQPKQVLKMEVAVLKKIQGREHSCRFVGCGRNDRFNYLVMSLQGRNLAELRRNTPRGIFSVSTMLKLGRQILDSIETIHMVGFLHRDVKPSNFAMGRLPQTARIVYILDFGLSRQYLNVDDEVRTPRPIAGFRGTVRYASTNAHMNREMGRHDDLWSMFYMLVEMVTGQLPWRKLKDKEQVGQIKQSFDHTILLRHLPSEFRLFLEHVQSLTYFDSPDYTMLRNLFDECMLRKRVHESDLFDWETA-----PSTNQ-EEVEIG----------NTQPYVDG--RPTGSQ 325

[Close]

BLAST of Tau tubulin kinase 1a vs. Planmine SMEST
Match: SMESG000002855.1 (SMESG000002855.1)

HSP 1 Score: 424.476 bits (1090), Expect = 8.955e-130
Identity = 191/314 (60.83%), Postives = 243/314 (77.39%), Query Frame = 1

Query:  100 MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVALKLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGKNLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAMGRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHFNKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLRHMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEIVVHQEPNSTNKANE 1041
            M S TS ++DL+ PG IIKERW+++KKIGGGGFG+IYEA DL + E VA+K+ES +Q+KQVLKMEVAVLK+LQG  HVC F GCGRN+ FNYVVM+LQG+NL ++RR+  +G FSIS+ +R+  Q+L+ IESIHSVGFLHRDIKPSNFA+G+     R + MLD+GLARQY N +G+VR PR VAGFRGTVRYAS NAH N+ELGRHDDLWSL Y+  E +TG+LPWRK+KDKEQVG +KQ  DHN LL+ MP E + +L++IQ L YF KPDY+ +++   + + RK     D FDWE++      S NK ++
Sbjct:    1 MTSATSSTADLVIPGTIIKERWKISKKIGGGGFGEIYEASDLQTNESVAIKVESTKQTKQVLKMEVAVLKRLQGKTHVCHFIGCGRNELFNYVVMTLQGRNLADIRRSMKRGCFSISTTMRIGIQILDSIESIHSVGFLHRDIKPSNFALGKSTELSRVIIMLDYGLARQYTNVNGDVRAPRQVAGFRGTVRYASVNAHQNRELGRHDDLWSLYYILAEFITGELPWRKIKDKEQVGTMKQTFDHNQLLKFMPREIRPVLEYIQTLTYFDKPDYNLIRSYFREYLKRKNLNDADIFDWEVINDNSGISGNKMDQ 314

The following BLAST results are available for this feature:

BLAST of Tau tubulin kinase 1a vs. Ensembl Human
BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
BLAST of Tau tubulin kinase 1a vs. Ensembl Zebrafish
BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
BLAST of Tau tubulin kinase 1a vs. Ensembl Mouse
BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
BLAST of Tau tubulin kinase 1a vs. TrEMBL
BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
BLAST of Tau tubulin kinase 1a vs. Planmine SMEST

BLAST of Tau tubulin kinase 1a vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
TTBK2	2.745e-138	68.62	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK1	2.249e-133	67.58	tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK2	4.122e-132	68.62	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK1	4.307e-120	68.46	tau tubulin kinase 1 [Source:HGNC Symbol;Acc:HGNC:...	[more]
TTBK2	2.154e-111	59.31	tau tubulin kinase 2 [Source:HGNC Symbol;Acc:HGNC:...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk-7	6.546e-115	57.24	Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:Q...	[more]
ttbk-2	2.490e-71	42.86	Tau TuBulin Kinase [Source:UniProtKB/TrEMBL;Acc:O...	[more]
R13H9.5	1.076e-70	42.51	pep chromosome:WBcel235:IV:5065746:5066987:-1 gene...	[more]
Y38H8A.3	7.996e-69	40.48	pep chromosome:WBcel235:IV:13472497:13474005:1 gen...	[more]
C39H7.1	1.307e-68	40.14	pep chromosome:WBcel235:IV:5631895:5633379:1 gene:...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Asator	1.216e-135	67.69	gene:FBgn0039908 transcript:FBtr0300344	[more]
Asator	4.949e-133	67.69	gene:FBgn0039908 transcript:FBtr0344869	[more]
Asator	4.949e-133	67.69	gene:FBgn0039908 transcript:FBtr0332908	[more]
Asator	1.094e-132	60.62	gene:FBgn0039908 transcript:FBtr0332904	[more]
Asator	1.979e-132	67.69	gene:FBgn0039908 transcript:FBtr0332905	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk1a	7.991e-137	67.80	tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk1a	7.991e-137	67.80	tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk1b	5.248e-133	68.28	tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk2a	1.494e-132	67.00	tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12...	[more]
ttbk2a	4.389e-132	67.00	tau tubulin kinase 2a [Source:ZFIN;Acc:ZDB-GENE-12...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
col24a1	1.544e-137	67.54	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	3.900e-133	69.31	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	1.085e-132	69.31	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	2.216e-129	70.44	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]
col24a1	8.462e-112	58.92	collagen, type XXIV, alpha 1 [Source:Xenbase;Acc:X...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ttbk1	4.108e-137	67.58	tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk2	2.762e-135	67.92	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk1	2.241e-133	67.58	tau tubulin kinase 1 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk2	2.214e-132	68.62	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]
Ttbk2	2.214e-132	68.62	tau tubulin kinase 2 [Source:MGI Symbol;Acc:MGI:21...	[more]

BLAST of Tau tubulin kinase 1a vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q5TCY1\|TTBK1_HUMAN	1.080e-132	67.58	Tau-tubulin kinase 1 OS=Homo sapiens OX=9606 GN=TT...	[more]
sp\|Q6PCN3\|TTBK1_MOUSE	1.568e-132	67.58	Tau-tubulin kinase 1 OS=Mus musculus OX=10090 GN=T...	[more]
sp\|Q3UVR3\|TTBK2_MOUSE	1.549e-131	68.62	Tau-tubulin kinase 2 OS=Mus musculus OX=10090 GN=T...	[more]
sp\|Q6IQ55\|TTBK2_HUMAN	1.980e-131	68.62	Tau-tubulin kinase 2 OS=Homo sapiens OX=9606 GN=TT...	[more]
sp\|Q8IMC6\|ASATR_DROME	1.538e-130	67.69	Tau-tubulin kinase homolog Asator OS=Drosophila me...	[more]

BLAST of Tau tubulin kinase 1a vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A1S5XVZ9	0.000e+0	95.80	LPT OS=Schmidtea mediterranea OX=79327 GN=LPT PE=2...	[more]
A0A4U5U3D5	6.276e-142	68.47	Tau-tubulin kinase 1 OS=Collichthys lucidus OX=240...	[more]
G3Q7K7	7.907e-142	68.47	Tau tubulin kinase 1a OS=Gasterosteus aculeatus OX...	[more]
A0A3P9CDN0	3.744e-139	69.15	Tau tubulin kinase 1a OS=Maylandia zebra OX=106582...	[more]
A0A3B4GI78	3.744e-139	69.15	Tau tubulin kinase 1a OS=Pundamilia nyererei OX=30...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk1a	1.110e-138	67.46	tau tubulin kinase 1a [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk1b	1.817e-137	68.97	tau tubulin kinase 1b [Source:ZFIN;Acc:ZDB-GENE-10...	[more]
ttbk2b	1.715e-128	66.67	tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
ttbk2b	1.451e-106	58.59	tau tubulin kinase 2b [Source:ZFIN;Acc:ZDB-GENE-03...	[more]
csnk1db	2.903e-47	35.50	casein kinase I [Source:NCBI gene;Acc:103030301]	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000004926.1	7.013e-105	66.07	pep scaffold:Pmarinus_7.0:GL480178:196:11423:1 gen...	[more]
ENSPMAT00000008477.1	6.204e-44	35.29	pep scaffold:Pmarinus_7.0:GL482342:316:9736:-1 gen...	[more]
csnk1g2a	6.780e-41	31.03	casein kinase 1, gamma 2a [Source:ZFIN;Acc:ZDB-GEN...	[more]
csnk1g1	2.616e-32	32.35	casein kinase 1, gamma 1 [Source:NCBI gene;Acc:494...	[more]
ENSPMAT00000001691.1	9.113e-31	39.18	pep scaffold:Pmarinus_7.0:GL476581:539457:546336:1...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
HRR25	5.973e-41	34.69	Conserved casein kinase; regulates diverse events ...	[more]
YCK2	1.046e-34	28.57	Palmitoylated plasma membrane-bound casein kinase ...	[more]
YCK1	2.558e-34	27.92	Palmitoylated plasma membrane-bound casein kinase ...	[more]
YCK3	1.683e-31	28.22	Palmitoylated vacuolar membrane-localized casein k...	[more]
SSK2	3.498e-15	28.29	MAP kinase kinase kinase of HOG1 mitogen-activated...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO46789	1.408e-123	64.26	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34742	1.689e-44	34.71	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46523	1.851e-41	34.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34289	4.768e-39	32.76	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO48738	1.442e-36	31.07	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Tau tubulin kinase 1a vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ttbk2a	5.554e-127	67.46	tau tubulin kinase 2 [Source:NCBI gene;Acc:1011741...	[more]
ttbk1a	1.806e-124	62.91	tau tubulin kinase 1 [Source:NCBI gene;Acc:1053541...	[more]
ttbk2b	1.207e-113	59.39	tau-tubulin kinase 2 [Source:NCBI gene;Acc:1011577...	[more]
ttbk2a	1.801e-112	59.39	tau tubulin kinase 2 [Source:NCBI gene;Acc:1011741...	[more]
csnk1db	2.258e-46	36.08	casein kinase 1 delta [Source:NCBI gene;Acc:101156...	[more]

BLAST of Tau tubulin kinase 1a vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000068893.1	0.000e+0	99.38	SMESG000068893.1	[more]
SMESG000068893.1	0.000e+0	91.78	SMESG000068893.1	[more]
SMESG000040592.1	0.000e+0	95.80	SMESG000040592.1	[more]
SMESG000048011.1	6.529e-147	63.72	SMESG000048011.1	[more]
SMESG000002855.1	8.955e-130	60.83	SMESG000002855.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30035594 ID=SMED30035594|Name=Tau tubulin kinase 1a|organism=Schmidtea mediterranea sexual|type=transcript|length=5145bp
TTTTTATGTGTAATGTCTAAAGCTTGTCACCATGAAAAGATAAAATTATC
AGATTAATGTAAGTTTATCAGTTAATAAATTAGAACAAATGACTTAAGTA
TGCCAAGTCCAACATCAGATTCAAGTGATTTATTGGAACCAGGATATATT
ATTAAAGAGAGATGGAGAGTTAATAAAAAAATTGGAGGTGGAGGATTTGG
TCAAATTTATGAAGCAATTGATTTATCTTCACAAGAAAAAGTCGCTTTAA
AATTAGAATCTGCACAACAGTCTAAACAAGTTTTAAAAATGGAAGTGGCA
GTTTTAAAAAAACTACAAGGATTAGATCATGTCTGTCGATTTTACGGCTG
TGGAAGAAATGATAAATTTAACTATGTAGTAATGTCTCTCCAAGGGAAAA
ACTTGGGAGAATTAAGACGAGCAACGTCTAAGGGTATTTTCTCAATTTCA
TCAATGGTAAGACTGACTAAACAAATGCTGGAGTGCATTGAAAGTATTCA
TTCGGTAGGATTTTTGCATAGAGATATTAAGCCCTCAAATTTTGCTATGG
GACGGTTGCCCAGTACATTTCGAAAAGTATATATGTTAGATTTTGGGTTG
GCTCGACAATATGTAAACACTGATGGGGAAGTTAGACCACCAAGACCCGT
TGCAGGGTTTCGTGGCACTGTTCGTTATGCTTCGGCAAATGCTCATTTCA
ATAAAGAACTCGGTAGACATGATGATCTTTGGTCACTTCTTTATTTAGCC
GTTGAAATGGTTACTGGCCAACTTCCTTGGAGAAAAGTGAAAGATAAAGA
ACAAGTTGGAAAATTAAAACAAAATGTCGACCATAATTTATTGTTGCGCC
ATATGCCTCTGGAGTTTAAACAAATACTGGACCACATACAAGAACTGCAT
TATTTTGCGAAACCCGATTACTCTAAACTTCAAAATCTTCTCGATCAAAC
CATGGCCAGAAAATTGTTCAAGTTCACAGATCCTTTTGATTGGGAAATAG
TCGTTCATCAAGAACCAAACAGTACCAACAAAGCAAATGAAGTCGAAGTC
CAAGCAATAAATAATAATTATATAAAAAAGGAAAATAGTAGCAAATACAA
GTCTGGCAATCGTCGTCCGTATACATCACAAGGAACGACATTTGCTCAAA
AAGAAAACAATAATGAAAACAGCAATGCAATGGATGCAACTCGCGCTACT
TATTTTCCTTATAATAATCAAAATGTCGATGAAAACGACAGCCAAGATAT
GGACGATAATAAGCTCGACAATAGAGTGAACGAGGAATATATAGTCAGTG
ACCAAATGCACAAATTAGATCTGAAATCGGACTTTTCTAAAATGAAATCC
GACACCAACAATAAATTTGCCAACATTAAATCTCCCAATGTTGCACGAAA
CAATTCCACAAAGCCCATATTGAGTATTGCCAATCTGAAATCATCGTGCA
ATAACCGTTCCGATCGTTCACCATCAGCGATCCATTTACCAAAAAAGAAA
ATTGAATTCACAAATTTTAAACTGCCACCGAAAATCAACACCTCCAAGTT
GGGAATCATCAGTCGAAATGATTCTCTCGGCCATATCAACAAAACCATAT
CCGATGAAAACATTATCTTTCACAGATCATCGAGTCTTGATCACAGCGCT
CCGTCAGTCCGCGGAATAATGAAAGGGCTATCTAACAATAATTTCTGCTC
CACCAGTCAACCGTTCCAAACCGATTCCGTTCTATCAATACCAGACATTC
ACAAAGTTGCTTCCGTCGATGATCACTACTTTCTCCGCTCGAATGACAAC
GACGTTGACGACGGCGATAACGACAGATACCAAGCGATCTATATCCATCC
AGAATCAGTATTATCGGATAAATATAGATTTTCTCACATACCCGATGCTA
TTATTTGTGATAAACCAGATTTACCTCTCACCAGAAAAGAAGATCTTATT
GTTTTATCGAAGAAAATCGATCCTTGTCTTTCAAGAACCAATTCCTCAGA
AAGAGGAATGACTTATATATCAAACGTAATGTGCAACAACAACAACAACA
ACAACAGTCCCTCAGTCCTAGTACAGTCCCAAGAATGTCTTCACCTGTCC
CGTTGATGCAGTCAAGTCCTCATTTCCAGCATCAGATGACGGCGGATTAC
GAGTCGGGTGTACAAGCGGCCCCATTTATGCCCGGTAAATCGATCACATA
TCCTCTGACCCCGGGTAATAGAGAGGAAATTGGCGGTTTTGAACCGCCAG
TTATTGTCACTCGTGTCAATGTCGATAGGAAGAATTTCGGCCCATCTGGC
GTCGCGGTGGGATCTGGAGATGGCAATGTTGTGAATAATCAGGATCAATA
TCGCCAGCAGATCATTATGACCAGTACTGATGGGATAAACTGTGTTAGTG
GCACTGCTATTACAGCTGATATGTGCTCTTCAGCTTCCTACCAATCCAAT
GCTACCAATCAGGTGACTATGAGCCATTACAAGCCACAATCTACCAACGC
TGGAAATATTATACAGCAATCATCAGCTGGCAATAACTCTCGCTCGTTCT
CCCGCTCAAACAGTGTCAATCATGACGACCCCAGGGCAATGAACACAATT
CAATCTAACAGTTTTGCTTACCGCCCACTCAGTAGTGCTAATATCACCAA
CAGCAACAGTACTATTGTCAACATCAACATCCAGTCTCAGCCGTCACATT
TGGATGACGTCATTGCCAGTGTCGTCTCTGATTCGATAGCTTATATAGAC
GAGAGTCCTGCTACACAATCAATCGCGTTACAGAGACAGAATTCAAATGA
CTCTTCGTCCTGTCTTGGCGGCGGCGGCAGCGGCTTTGATCATGATAAAT
CGGTGGCGGCGGCGGCGGCAGTAGCGTCATCACTAATGTCCGGTAGCGGA
GATCCGGCAGCGATTGAATCCCCACTCATTGCCGCCACTCAATACCAGAC
GGCTAATAATAATAACAACAATCGCTCAATCTCCAGGAATCTGAGCAGCA
ACCAATTGATATTCAATTCAGCAAACGCTTCCAATCCGCTCAGCATCAAC
CAGGCCAATCAATTATTGAATACCAAACAGTCGCAGAACAGCTTTTGGTT
GGCTACATCATCCAATATAAATCCCGGCGCAAAGCAACAACAGCAAATGT
GTATTTCAAATACGACTCAGCTGATTGGCCAGTTTGCTAATAATCAACCC
CAAACCAAAATTATCCAACATGGGCAAAATTTATATCAGATGTATGCTGC
CAATAATTCTCCTCAGCAGATCATTTACACTCCCTCATCGATTGAGCTCA
GTCCTAATATGAGCAGTAGCAGTACTGACCAGCAGCAAATCAATATGCTC
ACAGTTACCTCGCTGCCTAATCGGCAGAACAGTCAAACCTACCAATCAGT
TGCCGCGTTCAATCAGCCAATCAGCCAATACCAGAACGCAATTGAGCTAG
GGCAGTCTAACAAGAATCAACCGGAATCAGAAAAGAATAGTCTGATCGTT
CAGTCCGCTGACCAAGTGATGAGGCAATCACCAAGACAACAACAACAACA
GCAGCAGCCTAGCAACAGTAGTAGCAACGCGACCATGATCAAATTGAATC
AGCATTTCTCTGCCGGAATCCAATCAATGCAATCAAATAATAAGGCTAGT
AGCATCCAGATCCCTCAGATCTCCTCAAATCAATTCATCTATTCTCCCGG
CCCGACACTGCACGGCGCACAGAACCAGCAGGGCGTTGCCATGGTCGCCC
AGGCCAACAACCAATTGAATGCAGCGGCGGCCACCGGCAGCAGCTTGATT
ATGGGGCCGCCGGTGTCCAATCTCCGTCCCAACGCAAATGTCGTCACTCA
GAGATTCATTTGCTCAATAAACTCCAATTCCACCGCCAACACGATTCCTG
GCCAATCTCCTCAGCAGTATCTGATCAGCAGCACTCCACAGTCCAGTGCC
AGTGTCGGTGGTGCTGTCTGTACTGCTGGCTCACAAGCGCAGCAGCAGAT
TTCTTCCTTGATGATTTCATCTAATAATAGCAACAGTAGCAATTCTATGA
ATACTACTCAACAGCAGCAGCAGCAGGATTTGTCGATGAATTTTGGGCAT
TACAATTAGTAGGCCGTATTTTTGCCTAGCAACAGTTGCTATGGTATTGT
GCGCTGCCCTTATGCTGCATCACAATAATAATGTCATACATATTGTACAT
ATATATTATCTCAATTGCTCCAGCTGATTCCCGATTGCCCTTAGATACAG
TTACACTATTAATTATAATTCCCACCGCTAATGTTGCTATGTGGCGATGG
CGCATTCACTTAGCCCGCTTATTGTGATTATTTATCCATTTAATTATCAT
AACCATAATTATATCTCTTTCTGTCATTTTATTCAATTTGTGGTCAGCCG
CGATTTGCTTGTTGTCATTGGTTTCCATTGACCGGGACGGTTTGTGGATC
ATATATGTTATCATGGTTCCCATGCACGTCAGGCGGTATGGAAATGAGAG
TTCGTGCTGTTTATATGATTATCAAACACCTCGCATGCATATATATGAGG
CCGGGCAACGGATAAATTGTCACAGTGAAGGCATTTACCACTTACCCTTG
AATACCCTAGTTGCATGATTATATTTGCTTATTATTATGATTTTACAGTT
CTCCATGCCTCTCAGTTCTATTAGCAGCGTGCAGTGCGTTTATCTATTCT
CCTATCCAATTAGTGAGACCCTTGAGCAGATGGATTGAAGGTCGCTACTT
CAACTCACGCTGAGTAGTTTTTTGTAAATTGATTTTACAAGATAAGAGAT
CGATAAAAACAGACGTGTCGATTGCGTGTGATTATTGTTGTGCAGCATTT
GGTTGAGTTGTTGAAAATGTTCGTACTTGTTAAAGATACTCGACCTGGAC
GACCATCCAAGATCGATAGTGAATTTTTGCTTAGTAGAATTTAATAAAAC
TCTACTTCGACAAGTAAATCTGCTCAATTTATATTTACATTTTCTACTTT
GATTTCGTGTTTTTCTGCCAGTGATTTTATTAGATTGGATTCAAATCGTT
TGCCTGTCACACTATTAGTCTTGGTGCACCAAATCGTAAATTCCAATTAT
TTCTTAATATATTTGCAGTCGTATTTTCATATTGTGTTGACAGAT

protein sequence of SMED30035594-orf-1

>SMED30035594-orf-1 ID=SMED30035594-orf-1|Name=SMED30035594-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=675bp
MSSPVPLMQSSPHFQHQMTADYESGVQAAPFMPGKSITYPLTPGNREEIG
GFEPPVIVTRVNVDRKNFGPSGVAVGSGDGNVVNNQDQYRQQIIMTSTDG
INCVSGTAITADMCSSASYQSNATNQVTMSHYKPQSTNAGNIIQQSSAGN
NSRSFSRSNSVNHDDPRAMNTIQSNSFAYRPLSSANITNSNSTIVNINIQ
SQPSHLDDVIASVVSDSIAYIDESPATQSIALQRQNSNDSSSCLGGGGSG
FDHDKSVAAAAAVASSLMSGSGDPAAIESPLIAATQYQTANNNNNNRSIS
RNLSSNQLIFNSANASNPLSINQANQLLNTKQSQNSFWLATSSNINPGAK
QQQQMCISNTTQLIGQFANNQPQTKIIQHGQNLYQMYAANNSPQQIIYTP
SSIELSPNMSSSSTDQQQINMLTVTSLPNRQNSQTYQSVAAFNQPISQYQ
NAIELGQSNKNQPESEKNSLIVQSADQVMRQSPRQQQQQQQPSNSSSNAT
MIKLNQHFSAGIQSMQSNNKASSIQIPQISSNQFIYSPGPTLHGAQNQQG
VAMVAQANNQLNAAAATGSSLIMGPPVSNLRPNANVVTQRFICSINSNST
ANTIPGQSPQQYLISSTPQSSASVGGAVCTAGSQAQQQISSLMISSNNSN
SSNSMNTTQQQQQQDLSMNFGHYN*

protein sequence of SMED30035594-orf-2

>SMED30035594-orf-2 ID=SMED30035594-orf-2|Name=SMED30035594-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=669bp
MPSPTSDSSDLLEPGYIIKERWRVNKKIGGGGFGQIYEAIDLSSQEKVAL
KLESAQQSKQVLKMEVAVLKKLQGLDHVCRFYGCGRNDKFNYVVMSLQGK
NLGELRRATSKGIFSISSMVRLTKQMLECIESIHSVGFLHRDIKPSNFAM
GRLPSTFRKVYMLDFGLARQYVNTDGEVRPPRPVAGFRGTVRYASANAHF
NKELGRHDDLWSLLYLAVEMVTGQLPWRKVKDKEQVGKLKQNVDHNLLLR
HMPLEFKQILDHIQELHYFAKPDYSKLQNLLDQTMARKLFKFTDPFDWEI
VVHQEPNSTNKANEVEVQAINNNYIKKENSSKYKSGNRRPYTSQGTTFAQ
KENNNENSNAMDATRATYFPYNNQNVDENDSQDMDDNKLDNRVNEEYIVS
DQMHKLDLKSDFSKMKSDTNNKFANIKSPNVARNNSTKPILSIANLKSSC
NNRSDRSPSAIHLPKKKIEFTNFKLPPKINTSKLGIISRNDSLGHINKTI
SDENIIFHRSSSLDHSAPSVRGIMKGLSNNNFCSTSQPFQTDSVLSIPDI
HKVASVDDHYFLRSNDNDVDDGDNDRYQAIYIHPESVLSDKYRFSHIPDA
IICDKPDLPLTRKEDLIVLSKKIDPCLSRTNSSERGMTYISNVMCNNNNN
NNSPSVLVQSQECLHLSR*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000020	protonephridia
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0000429	neoblast
PLANA:0002089	reproductive organ
PLANA:0002142	parenchyma

Vocabulary: **INTERPRO**
Term	Definition
IPR000719	Prot_kinase_dom
IPR017441	Protein_kinase_ATP_BS
IPR011009	Kinase-like_dom_sf

Vocabulary: **molecular function**
Term	Definition
GO:0005524	ATP binding
GO:0004672	protein kinase activity
GO:0000166	nucleotide binding
GO:0004674	protein serine/threonine kinase activity
GO:0016301	kinase activity
GO:0016740	transferase activity

Vocabulary: **biological process**
Term	Definition
GO:0006468	protein phosphorylation
GO:0008360	regulation of cell shape
GO:0016310	phosphorylation
GO:0018105	peptidyl-serine phosphorylation
GO:0021762	substantia nigra development

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005737	cytoplasm
GO:0005829	cytosol

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 447..467
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 477..498
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 648..673