alpha-1,3/1,6-mannosyltransferase ALG2

Overview
Namealpha-1,3/1,6-mannosyltransferase ALG2
Smed IDSMED30035589
Length (bp)1419
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of alpha-1,3/1,6-mannosyltransferase ALG2 (SMED30035589) t-SNE clustered cells

Violin plots show distribution of expression levels for alpha-1,3/1,6-mannosyltransferase ALG2 (SMED30035589) in cells (dots) of each of the 12 neoblast clusters.

 

back to top

 

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of alpha-1,3/1,6-mannosyltransferase ALG2 (SMED30035589) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for alpha-1,3/1,6-mannosyltransferase ALG2 (SMED30035589) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

back to top

 

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

back to top
Anatomical Expression

PAGE et. al., 2020



SMED30035589

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parenchymaSMED30035589SMESG000043780.1 dd_Smed_v4_6228_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035589SMESG000043780.1 SMESG000025873.1 Contig45288uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035589SMESG000043780.1 SMESG000025873.1 Contig45288newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Human
Match: ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23159])

HSP 1 Score: 336.65 bits (862), Expect = 2.111e-111
Identity = 172/407 (42.26%), Postives = 262/407 (64.37%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF--GRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF--KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMEN-----DFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            + FLHPDLG+GGAER ++DAA+AL+  G  V + T H+D  HCF E++  +L V   G +LPR +   GR  A  AY+R++F ALY++     +FD++  DQ+SA IP+ ++     K+LFY HFPD+LL+KR+   K++YR PID+IE+++   AD IL NS+FTA V++E F      DP ++YP  N+ +  S       ++ E++++        L LSINRYE KKN+ L L A  +LR  L   D  +++  +  GGYD+ V EN + ++ L +++   ++      L+S ++  K++ L   + +LYTPSNEHFGIVP+EAMY++CPVIAVNSGGP E++   +TGFLCE DP  FSE++++ I + +L+  +G AG  R  E+FS +AF ++L   V++
Sbjct:   17 VLFLHPDLGVGGAERLVLDAALALQARGCSVKIWTAHYDPGHCFAESR--ELPVRCAGDWLPRGLGWGGRGAAVCAYVRMVFLALYVLFLADEEFDVVVCDQVSACIPVFRLARRRKKILFYCHFPDLLLTKRDSFLKRLYRAPIDWIEEYTTGMADCILVNSQFTAAVFKETFKSLSHIDPDVLYPSLNVTSFDS-------VVPEKLDDLVPKGKKFLLLSINRYERKKNLTLALEALVQLRGRLTSQD-WERVHLIVAGGYDERVLENVEHYQELKKMVQQSDLGQYVTFLRSFSDKQKISLLHSCTCVLYTPSNEHFGIVPLEAMYMQCPVIAVNSGGPLESIDHSVTGFLCEPDPVHFSEAIEKFIREPSLKATMGLAGRARVKEKFSPEAFTEQLYRYVTK 413
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Human
Match: ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23159])

HSP 1 Score: 242.662 bits (618), Expect = 4.098e-76
Identity = 126/305 (41.31%), Postives = 195/305 (63.93%), Query Frame = 2 
Query:  407 ISAPIPLLKIFGF--KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMEN-----DFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            +SA IP+ ++     K+LFY HFPD+LL+KR+   K++YR PID+IE+++   AD IL NS+FTA V++E F      DP ++YP  N+ +  S       ++ E++++        L LSINRYE KKN+ L L A  +LR  L   D  +++  +  GGYD+ V EN + ++ L +++   ++      L+S ++  K++ L   + +LYTPSNEHFGIVP+EAMY++CPVIAVNSGGP E++   +TGFLCE DP  FSE++++ I + +L+  +G AG  R  E+FS +AF ++L   V++
Sbjct:   24 VSACIPVFRLARRRKKILFYCHFPDLLLTKRDSFLKRLYRAPIDWIEEYTTGMADCILVNSQFTAAVFKETFKSLSHIDPDVLYPSLNVTSFDS-------VVPEKLDDLVPKGKKFLLLSINRYERKKNLTLALEALVQLRGRLTSQD-WERVHLIVAGGYDERVLENVEHYQELKKMVQQSDLGQYVTFLRSFSDKQKISLLHSCTCVLYTPSNEHFGIVPLEAMYMQCPVIAVNSGGPLESIDHSVTGFLCEPDPVHFSEAIEKFIREPSLKATMGLAGRARVKEKFSPEAFTEQLYRYVTK 320
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Human
Match: ALG2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:23159])

HSP 1 Score: 102.449 bits (254), Expect = 2.732e-25
Identity = 52/120 (43.33%), Postives = 74/120 (61.67%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSI--FGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQ-ISAPIPLLKIFGFKVL 454
             + FLHPDLG+GGAER ++DAA+AL+  G  V + T H+D  HCF E++  +L V   G +LPR +   GR  A  AY+R++F ALY++     +FD++  DQ I  P+ L    G  VL
Sbjct:   16 SVLFLHPDLGVGGAERLVLDAALALQARGCSVKIWTAHYDPGHCFAESR--ELPVRCAGDWLPRGLGWGGRGAAVCAYVRMVFLALYVLFLADEEFDVVVCDQAICIPLSLCSEPGHTVL 133
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Human
Match: ALG11 (ALG11 alpha-1,2-mannosyltransferase [Source:HGNC Symbol;Acc:HGNC:32456])

HSP 1 Score: 78.1814 bits (191), Expect = 9.081e-15
Identity = 90/323 (27.86%), Postives = 145/323 (44.89%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DMLLSKRN-----------------GIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKL-RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQ 1273
            +YID +     +PL K I G +V  Y H+P    DML   +N                    K IY     FI     S +D+++ NS +T N     +     ++  IVYP  ++           P+ E++M    +L +S+ ++  +KN  L + AFAKL  K++ +S    KL+ +  GG  +   E R     L +L  DL +        +   D   N+L  A+  L+T  NEHFGI  VE M     ++A NSGGP+  +V      +TGFL ES+ D ++E++  ++     +R       + +   FS + F+
Sbjct:  171 VYIDSMGYAFTLPLFKYIGGCQVGSYVHYPTISTDMLSVVKNQNIGFNNAAFITRNPFLSKVKLIYYYLFAFIYGLVGSCSDVVMVNSSWTLNHILSLWKVGNCTN--IVYPPCDVQTFLDI-----PLHEKKMTPGHLL-VSVGQFRPEKNHPLQIRAFAKLLNKKMVESPPSLKLVLI--GGCRNKDDELR--VNQLRRLSEDLGVQEYVEFKINIPFDELKNYLSEATIGLHTMWNEHFGIGVVECMAAGTIILAHNSGGPKLDIVVPHEGDITGFLAESEED-YAETIAHILSMSAEKRLQIRKSARASVSRFSDQEFE 480
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Celegans
Match: algn-2 (Asparagine Linked Glycosylation (ALG) homolog, Nematode [Source:UniProtKB/TrEMBL;Acc:Q19265])

HSP 1 Score: 304.294 bits (778), Expect = 2.284e-99
Identity = 179/401 (44.64%), Postives = 246/401 (61.35%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFG-FKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI--DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVS 1297
            ++  LHPDLGIGGAER IVDAA+ L+  G  V + TN +  SHCF ET   DL++  V  ++PRSIFG+  A  AYL++I AALYI++++  D D+I  D +SA   +L+ F   K++FY HFPD LL+KR+G  K  YR  ID+IE+++   AD+I  NS FT NV RE F      +  ++YP  N +   S  AS     EE       +F S+NR+E KKNI L L AF KL+  L  +D+  +   V  GGYD    EN + +  L + +  LE+  D   FL  S ++  KVN ++R+ A+LYTP  EHFGIVPVEAMYL  PVIAVN+GGP E+V +  TGFL +   +AF+E M  L+ DE + R + E G +   + F+F+AF +KL  I+ 
Sbjct:    3 RVTILHPDLGIGGAERLIVDAAVGLQDRGHSVRIFTNQYSRSHCFQETL--DLDICTVVPWIPRSIFGKGHALCAYLKMIIAALYIVIYH-KDTDVILSDSVSASQFVLRHFSKAKLVFYCHFPDRLLTKRDGNLKAFYRNIIDWIEEYTTGLADVICVNSNFTKNVVRETFKSLASQELTVLYPSLNTEFFDSIEAS-DDFGEEIPRGTKYVFTSLNRFERKKNIVLALDAFEKLKSNL-PADEFSQCHLVIAGGYDLKNPENIEHYDELVEHMKKLELPADQIVFL-HSPSDTQKVNLIRRSRAVLYTPDREHFGIVPVEAMYLGTPVIAVNTGGPCESVRNNETGFLVDQTAEAFAEKMIDLMKDEEMYRRMSEEGPKWVQKVFAFEAFARKLDEIIQ 397
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Celegans
Match: bus-8 (Glycosyltransferase [Source:UniProtKB/TrEMBL;Acc:G5ECB6])

HSP 1 Score: 127.102 bits (318), Expect = 5.972e-32
Identity = 96/347 (27.67%), Postives = 169/347 (48.70%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF---KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTG 1138
            +  +HP+   GG++R  V         G +VT +T   D     +  KN   + V +     R +  +L     + + +    +++  N N  D+  ID  ++ +P++K + F   K+LFY HFP  L++       + Y   I  +E+      D I  NS FTA  + +       +   +VYP  +ID + S+S   P    +R +N+   FLS+NR+  +K +++ + A + L+++ +    H +L     G     + E+R  +  L ++  +L + +    + S  + VK    ++    LYTP NEHFGIVP+EA+  + PVI  +SGGP ETV++ +TG
Sbjct:    3 VVIVHPEQWNGGSDRCTVALIRHFVSQGHRVTWLTTMID-----EYWKNHTFDGVEI-----REVGLKLHPGDWWSQNVALGWHMVFSNLNP-DVAIIDHSASCVPMIK-WRFPQCKILFYCHFPQQLVTPSRFFLYRWYAKLIGIVEEELFGHIDQIFVNSNFTATQFCKVMPNIEKNKVRVVYPPCDIDWIVSASER-PVSRAQRAKNETYTFLSMNRFWPEKRLDIIIEAASILKQKGYHF--HVQLA----GSVMPHIPESRIYYEVLQRMTEELNVTDMVTFIPSPTDKVKFQLYQQCDTALYTPPNEHFGIVPIEALDQRRPVIVCDSGGPAETVLEDITG 330
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Celegans
Match: bus-8 (Glycosyltransferase [Source:UniProtKB/TrEMBL;Acc:G5ECB6])

HSP 1 Score: 127.102 bits (318), Expect = 5.972e-32
Identity = 96/347 (27.67%), Postives = 169/347 (48.70%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF---KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTG 1138
            +  +HP+   GG++R  V         G +VT +T   D     +  KN   + V +     R +  +L     + + +    +++  N N  D+  ID  ++ +P++K + F   K+LFY HFP  L++       + Y   I  +E+      D I  NS FTA  + +       +   +VYP  +ID + S+S   P    +R +N+   FLS+NR+  +K +++ + A + L+++ +    H +L     G     + E+R  +  L ++  +L + +    + S  + VK    ++    LYTP NEHFGIVP+EA+  + PVI  +SGGP ETV++ +TG
Sbjct:    3 VVIVHPEQWNGGSDRCTVALIRHFVSQGHRVTWLTTMID-----EYWKNHTFDGVEI-----REVGLKLHPGDWWSQNVALGWHMVFSNLNP-DVAIIDHSASCVPMIK-WRFPQCKILFYCHFPQQLVTPSRFFLYRWYAKLIGIVEEELFGHIDQIFVNSNFTATQFCKVMPNIEKNKVRVVYPPCDIDWIVSASER-PVSRAQRAKNETYTFLSMNRFWPEKRLDIIIEAASILKQKGYHF--HVQLA----GSVMPHIPESRIYYEVLQRMTEELNVTDMVTFIPSPTDKVKFQLYQQCDTALYTPPNEHFGIVPIEALDQRRPVIVCDSGGPAETVLEDITG 330
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Fly
Match: Alg2 (gene:FBgn0035401 transcript:FBtr0073023)

HSP 1 Score: 334.724 bits (857), Expect = 8.751e-111
Identity = 183/412 (44.42%), Postives = 255/412 (61.89%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILF--NFNDFDLIYIDQISAPIPLLKIFGF--KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSD-PLIVYPVPNID-------NLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSD-KHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            ++ FLHPDLGIGGAER +VDAA+ALK  G +V+ +TNHHD++HCF ET +G   V VVG +LPR +FGR  A  AYLR+++AA+Y   F       D++  D IS  IP+L+      KVLFY HFPD LLS R G+ K++YR+PI+++E+ ++  AD +L NS+FT  V+++   F RLS  P ++YP  +          L   SA L   +  R+  +  ++L INRYE KKN  L L +   L   L  +D K  +L+    GGYD    EN + F  L  L  +L++ +   LL+S  ++ K   L  A  LLYTP NEHFGIVP+E MY   PV+A+NSGGP ETVV   TGFLCE    +F  +M +L  DE LR ++G+ GH+R  ++FSF+AF  +L+ I+ +
Sbjct:    3 RVLFLHPDLGIGGAERLVVDAALALKERGHQVSFLTNHHDSTHCFKETADGTFPVHVVGDWLPRGLFGRFYAICAYLRMLYAAIYASFFMPQREQVDVVVCDLISVCIPVLRFAPHRPKVLFYCHFPDQLLSSREGLLKRLYRLPINWLEEHTIGLADKVLVNSKFTLRVFQD--TFRRLSTVPDVLYPSLHTQYFDQMQKKLEQRSALLDEPVHPRVPLNAFIYLDINRYERKKNHALALHSLRLLGDMLPATDFKRCRLIIA--GGYDTRCMENVEHFAELEHLTEELKLQDHVVLLRSPTDEEKCRLLFAAHCLLYTPENEHFGIVPLEGMYCSKPVVALNSGGPTETVVSTSTGFLCEKTEKSFGGAMLQLFRDEQLRVKMGDQGHKRVQQKFSFQAFADRLNGIIRD 410
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Fly
Match: Alg11 (gene:FBgn0037108 transcript:FBtr0078422)

HSP 1 Score: 56.225 bits (134), Expect = 3.233e-8
Identity = 84/337 (24.93%), Postives = 144/337 (42.73%), Query Frame = 2 
Query:  392 IYIDQISAPI--PLLKIFG-FKVLFYAHFP----DML-------LSKRNGIFKQIYRIP------IDFIEKFSLSF------ADIILYNSEFTAN----VYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDK-HDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPR----ETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVS 1297
            IYID +      PL +     KV  Y H+P    DML       +S  N   K + R P      + +   FS  +      A+ I+ NS +T N    ++   F   R      VYP   + +L+S        ++   + D  + LS+ ++  +K+  L L A  +LR  L Q +   +++  V  G   +   ++ +  +N+  L   L ++N      +   +  +   + A   ++T  NEHFGI  VE+M     ++A  SGGP     ET      GFL  +D   ++E++  +IV+ +    +  A  + + E FS + F+K     VS
Sbjct:  153 IYIDTMGYAFTYPLFRYLAQSKVGCYVHYPVISTDMLKRVQQRQMSHNNK--KYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDVPFKTHR------VYPPCEVSHLKS--------LQHTEKGDEFIILSVGQFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKLVIVGSCRN--EDDYERLKNMQDLTKHLSLENNVQFSVNVPYEDLLKLYQTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVETSAGSQNGFLA-TDAVEYAENILNIIVNNSEMNGIRNAA-RASVERFSEQEFEKNFLRAVS 469
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Fly
Match: Alg11 (gene:FBgn0037108 transcript:FBtr0333392)

HSP 1 Score: 56.225 bits (134), Expect = 3.233e-8
Identity = 84/337 (24.93%), Postives = 144/337 (42.73%), Query Frame = 2 
Query:  392 IYIDQISAPI--PLLKIFG-FKVLFYAHFP----DML-------LSKRNGIFKQIYRIP------IDFIEKFSLSF------ADIILYNSEFTAN----VYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDK-HDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPR----ETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVS 1297
            IYID +      PL +     KV  Y H+P    DML       +S  N   K + R P      + +   FS  +      A+ I+ NS +T N    ++   F   R      VYP   + +L+S        ++   + D  + LS+ ++  +K+  L L A  +LR  L Q +   +++  V  G   +   ++ +  +N+  L   L ++N      +   +  +   + A   ++T  NEHFGI  VE+M     ++A  SGGP     ET      GFL  +D   ++E++  +IV+ +    +  A  + + E FS + F+K     VS
Sbjct:  153 IYIDTMGYAFTYPLFRYLAQSKVGCYVHYPVISTDMLKRVQQRQMSHNNK--KYVARNPFLTWTKLAYYRLFSRMYKWVGCCAETIMVNSSWTENHILQLWDVPFKTHR------VYPPCEVSHLKS--------LQHTEKGDEFIILSVGQFRPEKDHPLQLQAIYELRTLLAQDEALWNQIKLVIVGSCRN--EDDYERLKNMQDLTKHLSLENNVQFSVNVPYEDLLKLYQTAHIGIHTMWNEHFGIGIVESMAAGLIMVAHKSGGPLLDIVETSAGSQNGFLA-TDAVEYAENILNIIVNNSEMNGIRNAA-RASVERFSEQEFEKNFLRAVS 469
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Zebrafish
Match: alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:ZFIN;Acc:ZDB-GENE-060502-2])

HSP 1 Score: 353.599 bits (906), Expect = 1.389e-117
Identity = 181/403 (44.91%), Postives = 262/403 (65.01%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF--KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSD--PLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKL-SNIVS 1297
            ++ FLHPDLGIGGAER +VDAA+AL+  G  V + T H+D  HCF ET + DL VV VG +LP S+FG   A  AYLR+I+  +Y++LF+  +FD+++ DQ+SA IP L++     KVLFY HFPD LL++R    K++YR PID+ E+ +   AD IL NS+FTA V+++   F +LS+    ++YP  N          L  ++ E       ++LSINRYE KKN+ L L A A L+  L   +  +++  V  GGYD+ V EN + +  L  L+  L +++    L+S ++  K++ L  ++ +LYTPSNEHFGIVP+E+MYL+CPVIAVNSGGP E+V    TGFLCE  P+ FSE+M+  + D  L++ +G+AG +R  + FS +AF ++L S+I S
Sbjct:   56 RVVFLHPDLGIGGAERLVVDAAVALRSRGCSVQIWTAHYDPQHCFSETLSPDLPVVCVGDWLPTSVFGYFHALCAYLRMIYLTIYLVLFSGEEFDVVFCDQVSACIPFLRLARQRKKVLFYCHFPDQLLTQRRSALKRLYRGPIDWFEELTTGMADRILVNSQFTAKVFKQ--TFPKLSEIHTDVLYPSLNSSAFDDEVEGLGGLLPE---GRSFIYLSINRYERKKNLPLALQALANLKDRLSVGE-WERVHLVMAGGYDERVVENVEHYEELRSLVTSLGLEDHVTFLRSFSDKQKLSLLHNSTCVLYTPSNEHFGIVPIESMYLRCPVIAVNSGGPLESVAHEETGFLCEPTPERFSEAMQNFVSDPKLKQRMGQAGRERVQQRFSMQAFTEQLYSHIAS 452
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Zebrafish
Match: alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:ZFIN;Acc:ZDB-GENE-060502-2])

HSP 1 Score: 175.637 bits (444), Expect = 1.680e-51
Identity = 95/239 (39.75%), Postives = 134/239 (56.07%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKEL 820
            ++ FLHPDLGIGGAER +VDAA+AL+  G  V + T H+D  HCF ET + DL VV VG +LP S+FG   A  AYLR+I+  +Y++LF+  +FD+++ DQ                        LL++R    K++YR PID+ E+ +   AD IL NS+FTA V+++ F         ++YP  N          L  ++ E       ++LSINRYE KKN+ L L A A L+  L
Sbjct:   21 RVVFLHPDLGIGGAERLVVDAAVALRSRGCSVQIWTAHYDPQHCFSETLSPDLPVVCVGDWLPTSVFGYFHALCAYLRMIYLTIYLVLFSGEEFDVVFCDQ------------------------LLTQRRSALKRLYRGPIDWFEELTTGMADRILVNSQFTAKVFKQTFPKLSEIHTDVLYPSLNSSAFDDEVEGLGGLLPEGRS---FIYLSINRYERKKNLPLALQALANLKDRL 232
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Zebrafish
Match: alg11 (ALG11 alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:407614])

HSP 1 Score: 69.3218 bits (168), Expect = 3.757e-12
Identity = 108/420 (25.71%), Postives = 178/420 (42.38%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGA-ERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF-----------GRLCAFFAYLRLIFAALYIILFNFNDF--DLIYIDQI--SAPIPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPII-------------EERMENDFILFLSINRYEHKKNIELGLLAFAKL--RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +AF HP    GG  ER +  A  AL+     V+ +    D     +E  +G      +   LPR +             +L   F  L     ++++      +F  DL YID +  +  +P+ + + G +V  Y H+P    DML  + +RN  F               K IY      +   + S +D+I+ NS +T            L   L ++  PN      +S   PP               EE+ +      +S+ ++  +K+ +L + AF KL  RKE+  + + + +  V  GG  +   E+R +   L  L  +L I D   F L     ++K + L  A+  L+T  NEHFGI  VE M     ++A  SGGP+  +V     G TGFL + D D ++++M+R++
Sbjct:   34 VAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNI--RLPRPVKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDL-YIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWT------------LGHILALWRTPN-----RTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPAGR-EAVKLVLIGGCRNQEDEDRVLM--LRGLCQELGIADRVEFKLNIPFQELKKD-LTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGGPTGFLAD-DEDNYADAMERIL 428
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Zebrafish
Match: alg11 (ALG11 alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:407614])

HSP 1 Score: 68.1662 bits (165), Expect = 7.329e-12
Identity = 108/420 (25.71%), Postives = 178/420 (42.38%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGA-ERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF-----------GRLCAFFAYLRLIFAALYIILFNFNDF--DLIYIDQI--SAPIPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPII-------------EERMENDFILFLSINRYEHKKNIELGLLAFAKL--RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +AF HP    GG  ER +  A  AL+     V+ +    D     +E  +G      +   LPR +             +L   F  L     ++++      +F  DL YID +  +  +P+ + + G +V  Y H+P    DML  + +RN  F               K IY      +   + S +D+I+ NS +T            L   L ++  PN      +S   PP               EE+ +      +S+ ++  +K+ +L + AF KL  RKE+  + + + +  V  GG  +   E+R +   L  L  +L I D   F L     ++K + L  A+  L+T  NEHFGI  VE M     ++A  SGGP+  +V     G TGFL + D D ++++M+R++
Sbjct:   63 VAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNIR--LPRPVKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDL-YIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWT------------LGHILALWRTPN-----RTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPAGR-EAVKLVLIGGCRNQEDEDRVLM--LRGLCQELGIADRVEFKLNIPFQELKKD-LTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGGPTGFLAD-DEDNYADAMERIL 457
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Zebrafish
Match: alg11 (ALG11 alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:407614])

HSP 1 Score: 68.1662 bits (165), Expect = 7.329e-12
Identity = 108/420 (25.71%), Postives = 178/420 (42.38%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGA-ERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF-----------GRLCAFFAYLRLIFAALYIILFNFNDF--DLIYIDQI--SAPIPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPII-------------EERMENDFILFLSINRYEHKKNIELGLLAFAKL--RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +AF HP    GG  ER +  A  AL+     V+ +    D     +E  +G      +   LPR +             +L   F  L     ++++      +F  DL YID +  +  +P+ + + G +V  Y H+P    DML  + +RN  F               K IY      +   + S +D+I+ NS +T            L   L ++  PN      +S   PP               EE+ +      +S+ ++  +K+ +L + AF KL  RKE+  + + + +  V  GG  +   E+R +   L  L  +L I D   F L     ++K + L  A+  L+T  NEHFGI  VE M     ++A  SGGP+  +V     G TGFL + D D ++++M+R++
Sbjct:   63 VAFFHPYCNAGGGGERVLWCALRALQNRYQDVSFVVYTGDQGVTAEEILDGARRRFNIR--LPRPVKFVFLKHRLLVEAKLYPHFTLLGQSVGSIFLGWEALTEFVPDL-YIDSMGFAFTLPVFRYLGGCQVGSYVHYPTISTDMLSVVRERNPRFNNADYISSNPVLSAIKVIYYCVFALLYGLAGSCSDVIMVNSTWT------------LGHILALWRTPN-----RTSVVYPPCDVQAFLDVPIGEDNEEKEQKKCHSLVSVGQFRPEKDHQLQIRAFKKLLDRKEVEPAGR-EAVKLVLIGGCRNQEDEDRVLM--LRGLCQELGIADRVEFKLNIPFQELKKD-LTDATIGLHTMWNEHFGIGIVECMAAGTIILAHKSGGPKLDIVVPYDGGPTGFLAD-DEDNYADAMERIL 457
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Xenopus
Match: kif3a (kinesin family member 3A [Source:Xenbase;Acc:XB-GENE-986464])

HSP 1 Score: 350.903 bits (899), Expect = 4.251e-117
Identity = 173/399 (43.36%), Postives = 261/399 (65.41%), Query Frame = 2 
Query:   95 MNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIF--GFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSS-ASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKL 1282
            M   + F+HPDLGIGGAER +VDAA+ALK  G  V + T+H+D  HCF ET++  + +   G +LPRS+ GR  A  AY+R+IF  LYI+  +  +FD+++ DQ+SA IP  K+     KVLFY HFPD LL++R  + K++YR PID++E+ +   AD IL NS FT+ +++E FA     +P ++YP  N+ N  S+    +  +   + +N   +FLSINR+E KKN+ L L +  KLRK L   +  +++  +  GGYD+ V EN + +  L +  +  +I N    L+S +++ K N L  A  +LYTPSNEHFGIVP+EAMY++CPVIAVNSGGP E+V + +TGFLC  +P+ F+++M++ + + +L+  +GE+GH R   +FS +AF  ++
Sbjct:    1 MGPSVLFVHPDLGIGGAERLVVDAALALKSRGCHVQVWTSHYDPDHCFSETRDSGIPIRCCGDWLPRSLLGRCHALCAYIRMIFLTLYIVFLSGEEFDVVFCDQVSACIPFFKLARDSKKVLFYCHFPDQLLTQRLSLVKRMYRAPIDWLEEKTTGMADCILVNSYFTSAIFKETFASLAHIEPTVLYPSLNVSNFESTVFEDVSDLFPAKRQN---IFLSINRFERKKNLHLALESMCKLRKRLSLLE-WERVHLILAGGYDERVLENVEHYVELKESAVKYDISNHVTFLRSFSDEQKRNLLHNAICVLYTPSNEHFGIVPIEAMYMRCPVIAVNSGGPLESVENNVTGFLCSPNPEQFADAMEKFVKNPDLKNRMGESGHIRVKSKFSTEAFSDQI 395
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Xenopus
Match: alg11 (ALG11, alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:394898])

HSP 1 Score: 53.9138 bits (128), Expect = 3.499e-7
Identity = 91/328 (27.74%), Postives = 138/328 (42.07%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DMLLSKR-------NGIF----------KQIYRIPIDFIEKFSLSFADIILYNSEFT-ANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNF--------LKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESM---------KRLIVDENLRRELGEAGHQ 1237
            IYID +     +PL K + G +V  Y H+P    DML   R       N  F          K IY      I  +  S +D+I+ NS +T A++        R S   IVYP  ++      + +    IEE         +SI ++  +K+  L + AFA L K+        KL+ +  GG  +   E+      L +L  +L I            + KVN         L  A+  L+T  NEHFGI  VE M     ++A NSGGP+  +V    +  TGFL +S  ++++ +M         +RL + +N RR +     Q
Sbjct:  169 IYIDSMGYAFTLPLFKYVGGCQVGCYVHYPTISMDMLSVVRSQNARFNNAAFISNNPVLSRLKLIYYYLFAVIYGWVGSCSDVIMVNSTWTFAHILDLWKCSERTS---IVYPPCDVQTFLDINLNQHKDIEEHS------IVSIGQFRPEKDHPLQICAFAALLKKKTTEKLKLKLILI--GGCRN--NEDELRVSELKKLSSELGI----------PVEFKVNIPFAELKKHLSEATIGLHTMWNEHFGIGIVECMAAGTIILAHNSGGPKLDIVVPYEEHETGFLADS-VESYAAAMDYILCLTPEQRLTIRQNARRSVARFSDQ 472
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Xenopus
Match: alg11 (ALG11, alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:394898])

HSP 1 Score: 53.5286 bits (127), Expect = 4.761e-7
Identity = 91/328 (27.74%), Postives = 138/328 (42.07%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DMLLSKR-------NGIF----------KQIYRIPIDFIEKFSLSFADIILYNSEFT-ANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNF--------LKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESM---------KRLIVDENLRRELGEAGHQ 1237
            IYID +     +PL K + G +V  Y H+P    DML   R       N  F          K IY      I  +  S +D+I+ NS +T A++        R S   IVYP  ++      + +    IEE         +SI ++  +K+  L + AFA L K+        KL+ +  GG  +   E+      L +L  +L I            + KVN         L  A+  L+T  NEHFGI  VE M     ++A NSGGP+  +V    +  TGFL +S  ++++ +M         +RL + +N RR +     Q
Sbjct:  164 IYIDSMGYAFTLPLFKYVGGCQVGCYVHYPTISMDMLSVVRSQNARFNNAAFISNNPVLSRLKLIYYYLFAVIYGWVGSCSDVIMVNSTWTFAHILDLWKCSERTS---IVYPPCDVQTFLDINLNQHKDIEEHS------IVSIGQFRPEKDHPLQICAFAALLKKKTTEKLKLKLILI--GGCRN--NEDELRVSELKKLSSELGI----------PVEFKVNIPFAELKKHLSEATIGLHTMWNEHFGIGIVECMAAGTIILAHNSGGPKLDIVVPYEEHETGFLADS-VESYAAAMDYILCLTPEQRLTIRQNARRSVARFSDQ 467
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Mouse
Match: Alg2 (asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) [Source:MGI Symbol;Acc:MGI:1914731])

HSP 1 Score: 340.887 bits (873), Expect = 3.815e-113
Identity = 177/403 (43.92%), Postives = 266/403 (66.00%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF--GRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFK--VLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERM-ENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            + FLHPD+GIGGAER ++DAA+AL+  G  V + T H+D +HCF ET+  +L+V   G +LPRS+   GR  A  +Y+R++F ALY++  +  +FD++  DQ+SA IP+ K+   +  VLFY HFPD+LL++RN   K+ YR PID+IE+++   AD IL NS++TA+V++E F      +P ++YP  NI    S   ++P  I++ + +    LFLSINRYE KKN+ L L +  +LR  L  S + DK+     GGYDD + EN + ++ L +++ + +++     L+S ++  K++ L     +LYTPSNEHFGIVP+EAMY++CPVIAVN+GGP E++V  +TGFLCE DP  FSE+M++ I   +L+  +G AG  R  E+FS  AF  +L   V++
Sbjct:   17 VLFLHPDMGIGGAERLVLDAALALQEYGCDVKIWTAHYDPNHCFIETR--ELSVQCAGDWLPRSLGWGGRGAAICSYVRMVFLALYVLFLSGEEFDVVVCDQVSACIPVFKLARRRKRVLFYCHFPDLLLTQRNSALKKFYRAPIDWIEEYTTGMADRILVNSQYTASVFKETFKTLSHRNPDVLYPSLNIG---SFDLAIPEKIDDLVPKGKQFLFLSINRYERKKNLPLALRSLVQLRNRL-PSQEWDKVHLFMAGGYDDRIPENVEHYKELKKMVQESDLERHVTFLRSFSDRQKISLLHGCLCVLYTPSNEHFGIVPLEAMYMQCPVIAVNNGGPLESIVHKVTGFLCEPDPVHFSEAMEKFIHKPSLKATMGLAGKARVAEKFSADAFADQLYQYVTK 413
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Mouse
Match: Alg2 (asparagine-linked glycosylation 2 (alpha-1,3-mannosyltransferase) [Source:MGI Symbol;Acc:MGI:1914731])

HSP 1 Score: 112.464 bits (280), Expect = 1.180e-28
Identity = 63/167 (37.72%), Postives = 102/167 (61.08%), Query Frame = 2 
Query:  470 PDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERM-ENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKS 967
            PD+LL++RN   K+ YR PID+IE+++   AD IL NS++TA+V++E F      +P ++YP  NI    S   ++P  I++ + +    LFLSINRYE KKN+ L L +  +LR  L  S + DK+     GGYDD + EN + ++ L +++ + +++     L+S
Sbjct:   13 PDLLLTQRNSALKKFYRAPIDWIEEYTTGMADRILVNSQYTASVFKETFKTLSHRNPDVLYPSLNIG---SFDLAIPEKIDDLVPKGKQFLFLSINRYERKKNLPLALRSLVQLRNRL-PSQEWDKVHLFMAGGYDDRIPENVEHYKELKKMVQESDLERHVTFLRS 175
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Mouse
Match: Alg11 (asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase) [Source:MGI Symbol;Acc:MGI:2142632])

HSP 1 Score: 79.337 bits (194), Expect = 2.110e-15
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--------------LSKRNGIF---KQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +YID +     +PL K + G +V  Y H+P    DML                 RN +    K IY     F+     S +DI++ NS +T N     +     ++  IVYP  ++           P+ E+++    +L +SI ++  +KN  L + AFAKL  E      H  L  V  GG  +   E R     L  L  +L + +N  F +    +++K N+L  A+  L+T  NEHFGI  VE M     ++A NSGGP+  +V      +TGFL ES+ + +++SM  ++
Sbjct:  129 VYIDSMGYAFTLPLFKYVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTN--IVYPPCDVQTFLD-----IPLHEKKVTPGHLL-VSIGQFRPEKNHALQIKAFAKLLNEKAAELGHS-LKLVLIGGCRNKDDEFR--VNQLRSLSENLGVQENVEFKINISFDELK-NYLSEATIGLHTMWNEHFGIGVVECMAAGTVILAHNSGGPKLDIVIPHEGQITGFLAESE-EGYADSMAHIL 411
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Mouse
Match: Alg11 (asparagine-linked glycosylation 11 (alpha-1,2-mannosyltransferase) [Source:MGI Symbol;Acc:MGI:2142632])

HSP 1 Score: 78.9518 bits (193), Expect = 2.793e-15
Identity = 87/296 (29.39%), Postives = 137/296 (46.28%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--------------LSKRNGIF---KQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +YID +     +PL K + G +V  Y H+P    DML                 RN +    K IY     F+     S +DI++ NS +T N     +     ++  IVYP  ++           P+ E+++    +L +SI ++  +KN  L + AFAKL  E      H  L  V  GG  +   E R     L  L  +L + +N  F +    +++K N+L  A+  L+T  NEHFGI  VE M     ++A NSGGP+  +V      +TGFL ES+ + +++SM  ++
Sbjct:  171 VYIDSMGYAFTLPLFKYVGGCRVGSYVHYPTISTDMLSVVKNQNPGFNNAAFISRNALLSKAKLIYYYLFAFVYGLVGSCSDIVMVNSSWTLNHILSLWKVGHCTN--IVYPPCDVQTFLDI-----PLHEKKVTPGHLL-VSIGQFRPEKNHALQIKAFAKLLNEKAAELGHS-LKLVLIGGCRNKDDEFR--VNQLRSLSENLGVQENVEFKINISFDELK-NYLSEATIGLHTMWNEHFGIGVVECMAAGTVILAHNSGGPKLDIVIPHEGQITGFLAESE-EGYADSMAHIL 453
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. UniProt/SwissProt
Match: sp|Q9DBE8|ALG2_MOUSE (Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Mus musculus OX=10090 GN=Alg2 PE=1 SV=2)

HSP 1 Score: 340.887 bits (873), Expect = 2.669e-112
Identity = 177/403 (43.92%), Postives = 266/403 (66.00%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF--GRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFK--VLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERM-ENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            + FLHPD+GIGGAER ++DAA+AL+  G  V + T H+D +HCF ET+  +L+V   G +LPRS+   GR  A  +Y+R++F ALY++  +  +FD++  DQ+SA IP+ K+   +  VLFY HFPD+LL++RN   K+ YR PID+IE+++   AD IL NS++TA+V++E F      +P ++YP  NI    S   ++P  I++ + +    LFLSINRYE KKN+ L L +  +LR  L  S + DK+     GGYDD + EN + ++ L +++ + +++     L+S ++  K++ L     +LYTPSNEHFGIVP+EAMY++CPVIAVN+GGP E++V  +TGFLCE DP  FSE+M++ I   +L+  +G AG  R  E+FS  AF  +L   V++
Sbjct:   17 VLFLHPDMGIGGAERLVLDAALALQEYGCDVKIWTAHYDPNHCFIETR--ELSVQCAGDWLPRSLGWGGRGAAICSYVRMVFLALYVLFLSGEEFDVVVCDQVSACIPVFKLARRRKRVLFYCHFPDLLLTQRNSALKKFYRAPIDWIEEYTTGMADRILVNSQYTASVFKETFKTLSHRNPDVLYPSLNIG---SFDLAIPEKIDDLVPKGKQFLFLSINRYERKKNLPLALRSLVQLRNRL-PSQEWDKVHLFMAGGYDDRIPENVEHYKELKKMVQESDLERHVTFLRSFSDRQKISLLHGCLCVLYTPSNEHFGIVPLEAMYMQCPVIAVNNGGPLESIVHKVTGFLCEPDPVHFSEAMEKFIHKPSLKATMGLAGKARVAEKFSADAFADQLYQYVTK 413
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. UniProt/SwissProt
Match: sp|Q9H553|ALG2_HUMAN (Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Homo sapiens OX=9606 GN=ALG2 PE=1 SV=1)

HSP 1 Score: 336.65 bits (862), Expect = 1.014e-110
Identity = 172/407 (42.26%), Postives = 262/407 (64.37%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF--GRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF--KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMEN-----DFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            + FLHPDLG+GGAER ++DAA+AL+  G  V + T H+D  HCF E++  +L V   G +LPR +   GR  A  AY+R++F ALY++     +FD++  DQ+SA IP+ ++     K+LFY HFPD+LL+KR+   K++YR PID+IE+++   AD IL NS+FTA V++E F      DP ++YP  N+ +  S       ++ E++++        L LSINRYE KKN+ L L A  +LR  L   D  +++  +  GGYD+ V EN + ++ L +++   ++      L+S ++  K++ L   + +LYTPSNEHFGIVP+EAMY++CPVIAVNSGGP E++   +TGFLCE DP  FSE++++ I + +L+  +G AG  R  E+FS +AF ++L   V++
Sbjct:   17 VLFLHPDLGVGGAERLVLDAALALQARGCSVKIWTAHYDPGHCFAESR--ELPVRCAGDWLPRGLGWGGRGAAVCAYVRMVFLALYVLFLADEEFDVVVCDQVSACIPVFRLARRRKKILFYCHFPDLLLTKRDSFLKRLYRAPIDWIEEYTTGMADCILVNSQFTAAVFKETFKSLSHIDPDVLYPSLNVTSFDS-------VVPEKLDDLVPKGKKFLLLSINRYERKKNLTLALEALVQLRGRLTSQD-WERVHLIVAGGYDERVLENVEHYQELKKMVQQSDLGQYVTFLRSFSDKQKISLLHSCTCVLYTPSNEHFGIVPLEAMYMQCPVIAVNSGGPLESIDHSVTGFLCEPDPVHFSEAIEKFIREPSLKATMGLAGRARVKEKFSPEAFTEQLYRYVTK 413
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. UniProt/SwissProt
Match: sp|O94738|ALG2_RHIPU (Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Rhizomucor pusillus OX=4840 GN=ALG2 PE=1 SV=1)

HSP 1 Score: 314.694 bits (805), Expect = 1.164e-101
Identity = 172/417 (41.25%), Postives = 243/417 (58.27%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF-KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLR-KELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLII-----------------DLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            +AF+HPDLGIGGAER +VDAA+ ++  G +V   T+HHD +HCF+ET++G L V V G +LPR+IFGR     A LR       +IL+  + +D+ ++DQ+SA +PLLK F   K+LFY HFPD LL++RN   K++YR P+D +E+ +   +D+I  NS FTA ++++ F     + P I+YP  N D          P + + +E D  + LSINR+E KKN+EL L AFA L+ K +   D       V  GGYD  V EN +    L+QL                   D+  D     L S  +  +   L +A  LLYTPSNEHFGI PVE MY   PVIAVN+GGP ETV +  TG L  SDPD ++E ++  I+++   +++G+ G Q    +FS  AF  +L  ++ E
Sbjct:    8 VAFIHPDLGIGGAERLVVDAAVGIQKKGHQVIFYTSHHDPNHCFEETRDGTLKVQVRGDWLPRTIFGRFYILCAILRQFVLVASLILWERHSYDIFFVDQLSACVPLLKWFTTAKILFYCHFPDKLLTQRNSTIKKLYRAPVDKMEELTTGMSDLIAVNSGFTAGMFKKSFPSVHQT-PQILYPPINFDAYDRPVDRNDPTV-KILETDKRVLLSINRFERKKNVELALRAFAALKIKNMVPKDVFANYRLVLAGGYDKRVRENVEYLEELDQLATEEFGLQTFTIHPSSAAADVPADAQVVFLCSFNDAQRTFLLDQAKLLLYTPSNEHFGITPVEGMYASVPVIAVNTGGPVETVKNKETGLLLPSDPDVWAEGIRDFIIEKYNGKQMGQHGRQHVQSKFSLPAFADRLEAMMIE 422
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. UniProt/SwissProt
Match: sp|Q7KWM5|ALG2_DICDI (Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Dictyostelium discoideum OX=44689 GN=alg2 PE=3 SV=1)

HSP 1 Score: 311.227 bits (796), Expect = 9.151e-101
Identity = 179/412 (43.45%), Postives = 244/412 (59.22%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGF-KVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIF-GFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFI---------LFLSINRYEHKKNIELGLLAFAKL--RKELHQSDK-HDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            IA LHPDLGIGGAER IVD A+ LK  G  ++TM T+ HD   CF ET NG+L+V V G + PR IF R     A +R + AALYII F+   +D+I +DQISA IPL K+F   KVLFY HFPD LL+ R  + K++YRIPID  E+F+   AD +L NS FT+++Y++ F   + S P ++YP+ N +    +  S      + +EN+ I          FLSINRYE KK+++L L AF+      E   S K  D++  V  GGYD  + EN +  + L     +  ++N    L +   + K   L     L+YTPS EHFGI P+E MY   PVIAVN+GGP ETVVDG TG+LC      F+ +  ++I D    +++G  G QR  ++FSFK F + L+ IV +
Sbjct:   10 IAILHPDLGIGGAERLIVDLALGLKSVGNNRITMYTSRHDPKRCFKETSNGELDVHVTGGYFPRHIFNRFMVICAIIRNLLAALYIIFFSGQKYDVIVLDQISASIPLFKLFTNSKVLFYCHFPDKLLTSRTSLIKRLYRIPIDLFEEFTTGCADQVLVNSNFTSSIYKQSFKHLKNS-PSVLYPIINTNEFDKTKQS-HNFSNQPIENNLINPIKLDDKKFFLSINRYERKKDLKLALDAFSVFISNSESGGSGKGKDEIYLVFAGGYDTGLKENVEHLQELKDKAKEYGLENRVIFLITINEEQKQWLLLNCCCLIYTPSFEHFGITPLEGMYAGKPVIAVNNGGPLETVVDGKTGYLCNPTVKDFANAFNKIINDPINSKKMGINGKQRVNDKFSFKPFAQNLNTIVKK 419
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. UniProt/SwissProt
Match: sp|Q96WW6|ALG2_SCHPO (Alpha-1,3/1,6-mannosyltransferase alg2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=alg2 PE=3 SV=2)

HSP 1 Score: 280.796 bits (717), Expect = 8.928e-88
Identity = 168/419 (40.10%), Postives = 241/419 (57.52%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPL-IVYPVPNIDNL-RSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEID-----------------NCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENL-RRELGEAGHQRACEEFSFKAFQKKL-SNIVS 1297
            KIAF+HPDLGIGGAER +VDAA+ L+  G +V + T+H D  HCF+E ++G + V V G +LP SIFGRL  F + LR ++  + I+L N+  FD I +DQ+S  +P L +    +LFY HFPD  L+KR GI K++YRIP D +E  S+  AD I+ NS+FTA+V+++  AF ++  PL IV+P  +I+   +     LP  I +R      L +S+NR+E KK+I L + AF+ LR     +++  + L +  GGYD  V+ENR+  + L +     ++                  N  FLL S  + V+   +  +  LLYTP NEHFGIVP+EAM  K PV+A  +GGP ETV+DG  G+L   D   +   +             +GEAG +    EFS  A  +K  S I+S
Sbjct:   18 KIAFIHPDLGIGGAERLVVDAAVGLQSLGKEVVVFTSHCDKKHCFEEIRDGTIKVKVYGDWLPSSIFGRLSIFCSSLRQVYLTM-ILLTNYMHFDAIIVDQLSTCVPFLLLASQMILFYCHFPDKYLAKRGGILKKLYRIPFDTVEAESVRLADRIVVNSKFTASVFKK--AFPKIRKPLRIVHPCVDIEAASKPLEFQLPEKILQRK-----LLISVNRFERKKDIRLAIDAFSALRD--LSANRFPEYLLLVAGGYDIRVSENRRYLKELQEFCEQKDLSYTTVKDNWDNITVAPSTNVLFLL-SVPSKVRDALISSSRILLYTPENEHFGIVPLEAMLRKVPVLAQTNGGPLETVIDGKNGWLRPRDAKIWGNVIYEATTSTTYDTAAMGEAGSEWVKNEFSTDAMARKFESEIMS 425
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. TrEMBL
Match: T1EF46 (Uncharacterized protein OS=Helobdella robusta OX=6412 GN=20195198 PE=4 SV=1)

HSP 1 Score: 397.897 bits (1021), Expect = 2.309e-132
Identity = 197/403 (48.88%), Postives = 281/403 (69.73%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFG-FKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNI---DNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            ++ F+HPDLGIGGAERAI+DAA+ALK  G +V ++T HHD +HCF+ET++G L+V+VVG +LPRS +GR  A FAYLR+I  A Y++ F+    DLI+ DQISA IP+LK+    KVLFY HFPD LL+ R  + K++YR+PID++E+ +   +D++L NS FTA+V++  F   R  DP ++YP+P++   DN    S++LP  ++ R     I FLSINRYE KKN+ L + + + LRK+L+ +   D +  V  GGYD+ V+EN++ +  L  L+  L + +     KS ++ +K+  L+ ++ LLYTPSNEHFGIVP+EAMY   PVIAVN+GGP+ETV+DG TG+LCE DPD F++ M + + + NL  ELG AG +R  + FSF AF +KL  IV +
Sbjct:    3 RVVFVHPDLGIGGAERAIIDAALALKSRGHEVKILTAHHDVNHCFEETRDGSLSVLVVGDWLPRSFWGRFYALFAYLRMICIACYLVFFSGLSPDLIFCDQISACIPVLKLMKKSKVLFYCHFPDFLLTDRKTLLKKLYRVPIDWLEEKTTGMSDVVLVNSNFTASVFKRTFTSLRHIDPQVLYPIPDLSMYDNFLVESSTLPSKMDAR-----ISFLSINRYERKKNLSLAVHSLSALRKKLNGN--LDNIQLVIAGGYDERVSENKEHYEELVNLVSQLNLKDHVSFYKSISSQMKLELLRVSTCLLYTPSNEHFGIVPIEAMYFGLPVIAVNNGGPKETVLDGKTGYLCEQDPDEFADKMLKFVKNPNLNYELGIAGKERVMKYFSFNAFTEKLDKIVHD 398
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. TrEMBL
Match: K1PCW5 (Alpha-1,3-mannosyltransferase ALG2 OS=Crassostrea gigas OX=29159 GN=CGI_10003533 PE=4 SV=1)

HSP 1 Score: 395.586 bits (1015), Expect = 3.684e-131
Identity = 193/397 (48.61%), Postives = 264/397 (66.50%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIV 1294
            ++ FLHPDLGIGGAERA++DAA+ALK    +V  +T HHD SHCF ETK+G L V  VG +LPR +FGR  A  AY+R+I+AA Y+++      D+++ DQISA IP+L +   +VLFY HFPDMLL+ R    K +YR PID +E+++   A  +L NS FTA +++E F       P ++YP+P+ D L   + ++     E++     LFLSINRYE KKNI L ++AF  L ++   S  H     +  GGYD+ VTENR+ ++ L  L+  L + +    L+S ++  K + L  A+ LLYTP NEHFGIVP+EAMYL+CPVIA NSGGP ETV DG TG+LC+  PD FSE+M + + DENL + LGEAG QR  ++FSFK F ++L +IV
Sbjct:    3 RVLFLHPDLGIGGAERAVIDAALALKSKNHEVQFVTAHHDPSHCFQETKDGTLKVTCVGDWLPRKVFGRFYALCAYIRMIYAAFYVVVSPSMQHDVVFCDQISACIPVLLLSSARVLFYCHFPDMLLTTRKSFLKTLYRKPIDKLEEYTTGMAHKVLVNSHFTAGIFKETFKSLGHVQPAVLYPIPDFDAL---NKAVDKEFVEKLPQKPFLFLSINRYERKKNISLAVMAFELLVEKHGTSKVH----LIIAGGYDERVTENREYYKELKDLVDQLSLTDHVTFLRSFSDAQKRSLLSSATCLLYTPENEHFGIVPIEAMYLQCPVIAANSGGPLETVADGATGYLCDPAPDKFSEAMSKFVEDENLHKVLGEAGKQRVIQKFSFKQFTEQLCDIV 392
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. TrEMBL
Match: A0A3Q8C0P9 (Alpha-1,3/1,6-mannosyltransferase OS=Locusta migratoria OX=7004 GN=ALG2 PE=2 SV=1)

HSP 1 Score: 389.423 bits (999), Expect = 6.376e-129
Identity = 201/401 (50.12%), Postives = 264/401 (65.84%), Query Frame = 2 
Query:  101 NKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSAS-LPPIIEER--MENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIV 1294
             KI  LHPDLGIGGAER +VD A+AL+  G  V  +T HHD  HCF ETK+G   V VVG +LPRS+FGR  A FAYLR+I+AA+Y++ F+    DL++ DQ+SA IP+L+  G KV+FY HFPD LLS R    KQ+YR P+D++E+ +   AD IL NS FTA V++  F       P ++YP  N D   S+SAS L  +IE+   + +D  +FLSINRYE KKN+ L L AFA+LR  L + DK  ++ F+  GGYD  V EN + F  L  L + L +      LKS ++ VK++ L  +  L+YTPSNEHFGIVP+EAM+ K PVIAVNSGGP ETVVDG+TGFLCE  P  F+E+M + + ++ L   +G  G     E+FSF +F K+L  IV
Sbjct:    2 GKIVLLHPDLGIGGAERLVVDVALALQKEGHDVQFVTAHHDPKHCFTETKDGSFQVTVVGDWLPRSVFGRFHAVFAYLRMIYAAIYLVFFSGIKPDLVFCDQVSACIPILRCRGLKVIFYCHFPDQLLSYRGSRLKQMYRAPLDWLEEVTTGMADKILVNSNFTAGVFKATFKRLERITPDVLYPSVNTDLFESTSASPLNQVIEDPAFLADDAFIFLSINRYERKKNLSLALRAFAELRTVL-EDDKWGRVFFIMAGGYDSRVQENVEHFTELVCLAVRLGVSEKVKFLKSPSDSVKLSLLYHSHCLIYTPSNEHFGIVPLEAMHAKKPVIAVNSGGPTETVVDGVTGFLCEPVPRKFAEAMAKFVSNKPLVNRMGLQGRGWVMEKFSFLSFSKQLQAIV 401
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. TrEMBL
Match: A0A1S3IJT3 (alpha-1,3/1,6-mannosyltransferase ALG2 OS=Lingula unguis OX=7574 GN=LOC106164980 PE=4 SV=1)

HSP 1 Score: 387.497 bits (994), Expect = 2.788e-128
Identity = 186/398 (46.73%), Postives = 269/398 (67.59%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            + F+HPDLGIGGAERA+VDAA+ALK +G  V  +T HHD SHCF+ET++G L +  VG +LPR +FGR  A  AY+R+I+AA+Y++ F+  + D+I+ DQISA IP L+I   K++FY HFPD+LL++R  +FK++YR+PID++E+++   A  IL NS+FTA V+++ F      +P ++YP+PN+  L      LP       E    LFLSINRYE KKN+ L +   AKL++ +     H     +  GGYD+ VTEN++ +  L +L   L +      ++S ++  K + L  A++L+YTP  EHFGIVPVEAM+++CPVIAV SGGP ETV D +TGFLC+  P +FSESM   + + N + E+G AG  R  E+FSF+AF ++L+N++ E
Sbjct:    9 VVFIHPDLGIGGAERAVVDAALALKSSGHSVQFVTAHHDPSHCFEETRDGQLKITAVGDWLPRHVFGRCAALCAYIRMIYAAIYLVFFSDINPDIIFCDQISACIPFLRISRVKIIFYCHFPDLLLTQRQSLFKRLYRLPIDWLEEWTTGMAHCILVNSKFTAGVFKDTFKTLGHINPEVLYPIPNLSTLGKPVDPLPKSHCPPKETK-TLFLSINRYERKKNLGLAIEGLAKLKESIPLYGIH----LIMAGGYDERVTENKEHYLELKELAEKLGVQTHVSFIRSFSDSEKRSLLSNATSLIYTPDKEHFGIVPVEAMFMQCPVIAVRSGGPVETVDDKVTGFLCDPTPQSFSESMLYFVKNPNAKEEMGRAGKLRVIEKFSFQAFSRQLNNLIME 401
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. TrEMBL
Match: A0A1S3HHC2 (alpha-1,3/1,6-mannosyltransferase ALG2-like OS=Lingula unguis OX=7574 GN=LOC106155289 PE=4 SV=1)

HSP 1 Score: 386.341 bits (991), Expect = 9.315e-128
Identity = 186/398 (46.73%), Postives = 268/398 (67.34%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            + F+HPDLGIGGAERA+VDAA+ALK +G  V  +T HHD SHCF+ET++G L +  VG +LPR +FGR  A  AY+R+I+AA+Y++ F+  + D+I+ DQISA IP L+I   K++FY HFPD+LL++R  +FK++YR PID++E+++   A  IL NS+FTA V+++ F      +P ++YP+PN+  L      LP       E    LFLSINRYE KKN+ L +   AKL++ +     H     +  GGYD+ VTEN++ +  L +L   L +      ++S ++  K + L  A++L+YTP  EHFGIVPVEAM+++CPVIAV SGGP ETV D +TGFLC+  P +FSESM   + + N + E+G AG  R  E+FSF+AF ++L+N++ E
Sbjct:    9 VVFIHPDLGIGGAERAVVDAALALKSSGHSVQFVTAHHDPSHCFEETRDGQLKITAVGDWLPRHVFGRCAALCAYIRMIYAAIYLVFFSDINPDIIFCDQISACIPFLRISRVKIIFYCHFPDLLLTQRQNMFKRLYRWPIDWLEEWTTGMAHCILVNSKFTAGVFKDTFKTLGHINPEVLYPIPNLSTLGKPVDPLPKSHCPPKETK-TLFLSINRYERKKNLGLAIEGLAKLKESIPLYGIH----LIMAGGYDERVTENKEHYLELKELAEKLGVQTHVSFIRSFSDSEKRSLLSNATSLIYTPDKEHFGIVPVEAMFMQCPVIAVRSGGPVETVDDKVTGFLCDPTPQSFSESMLYFVKNPNAKEEMGRAGKLRVIEKFSFQAFSRQLNNLIME 401
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Cavefish
Match: alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:NCBI gene;Acc:103028771])

HSP 1 Score: 345.125 bits (884), Expect = 4.548e-115
Identity = 180/400 (45.00%), Postives = 250/400 (62.50%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFK--VLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERM-----ENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKL 1282
            ++ FLHPDLGIGGAER +VDAA+AL   G  V + T H+D  HCF ET + DL VV  G +LP S+FG   A  AYLR+I+ A Y++  +  +FD+++ DQ+SA IP+L++   K  VLFY HFPD LL++R  + K++YR PID +E+ +   AD I+ NS+FTA V+++ F         ++YP  N        AS    +EE +     E   +LFLSINRYE KKN+ L L A   LR ++  S + +++  V  GGYD+ V EN Q +  L  L   L ++     L+S ++  KV  L  +  +LYTPSNEHFGIVPVEAMY +CPVIAV SGGP E+V  G TGFLC+  P++FSE+M   + +  L++ LG+AG  R  + FS +AF  +L
Sbjct:    3 RVVFLHPDLGIGGAERLVVDAAVALISRGCSVQIWTAHYDPQHCFSETLSPDLPVVCAGDWLPTSVFGYFHAICAYLRMIYVAFYLVFLSGEEFDVVFCDQVSACIPVLRLARHKKKVLFYCHFPDQLLTQRRSLLKRLYRAPIDRLEELTTGMADRIVVNSKFTAGVFKDTFPNLPGIHTDVLYPSLNF-------ASFDVEVEEDLSGLLPEGRRVLFLSINRYERKKNLPLALQALGALRDQV-SSKQWEQVHLVMAGGYDERVVENVQHYEELRSLAASLGVEEHVTFLRSFSDRQKVALLHGSCCVLYTPSNEHFGIVPVEAMYTRCPVIAVRSGGPLESVAHGETGFLCDPTPESFSEAMGHFLTEPGLKQRLGQAGRDRVIKRFSLEAFTDQL 394
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Cavefish
Match: alg11 (ALG11 alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:103039495])

HSP 1 Score: 68.9366 bits (167), Expect = 3.847e-12
Identity = 80/298 (26.85%), Postives = 139/298 (46.64%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFT-ANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKL-RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +YID +     +P+ + + G +V  Y H+P    DML  + +RN  F               K IY      +   + S +D+++ NS +T  ++     A  R S   +VYP  ++         L    E++ E      +S+ ++  +K+ +L + AF KL  K+  +    + +  +  GG  +   E+R +   L  L  +L + D   F L     D+K   ++ A+  L+T  NEHFGI  VE M     ++A  SGGP+  +V     G TGFL + D D+++E+M+R++
Sbjct:  131 LYIDSMGYAFTLPVFRYLGGCRVGSYVHYPTISTDMLNLVRERNPRFNNADYITNNPLLSAVKVIYYCAFALLYGLAGSCSDVVMVNSTWTLGHILALWRAPNRTS---VVYPPCDVQAF--LDVPLDEEEEQKGERKCHSLVSVAQFRPEKDHQLQIRAFRKLLDKKGAEPGGRESVKLMLIGGCRNQEDEDRVLM--LRGLCQELGVADRVEFKLNIPFEDLKKELVE-ATIGLHTMWNEHFGIGVVECMAAGTVILAHKSGGPKLDIVVPHDGGATGFLAD-DEDSYAEAMERIL 419
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Cavefish
Match: alg11 (ALG11 alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:103039495])

HSP 1 Score: 68.9366 bits (167), Expect = 4.029e-12
Identity = 102/406 (25.12%), Postives = 173/406 (42.61%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGA-ERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIF-----------GRLCAFFAYLRLIFAALYIILFNFNDFDL-IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFT-ANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKL-RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +AF HP    GG  ER +  A  AL+     V  +    D     ++  +G      +   LPR +              L   F  L     +L++       F   +YID +     +P+ + + G +V  Y H+P    DML  + +RN  F               K IY      +   + S +D+++ NS +T  ++     A  R S   +VYP  ++         L    E++ E      +S+ ++  +K+ +L + AF KL  K+  +    + +  +  GG  +   E+R +   L  L  +L + D   F L     D+K   ++ A+  L+T  NEHFGI  VE M     ++A  SGGP+  +V     G TGFL + D D+++E+M+R++
Sbjct:   63 VAFFHPYCNAGGGGERVLWCAIRALQNRYQDVDFVIYTGDQGVTDEQIVDGARRRFNI--RLPRPVRFVFLKHRLLVEASLYPHFTLLGQSIGSLFLGWEALTTFTPDLYIDSMGYAFTLPVFRYLGGCRVGSYVHYPTISTDMLNLVRERNPRFNNADYITNNPLLSAVKVIYYCAFALLYGLAGSCSDVVMVNSTWTLGHILALWRAPNRTS---VVYPPCDVQAF--LDVPLDEEEEQKGERKCHSLVSVAQFRPEKDHQLQIRAFRKLLDKKGAEPGGRESVKLMLIGGCRNQEDEDRVLM--LRGLCQELGVADRVEFKLNIPFEDLKKELVE-ATIGLHTMWNEHFGIGVVECMAAGTVILAHKSGGPKLDIVVPHDGGATGFLAD-DEDSYAEAMERIL 457
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Cavefish
Match: alg11 (ALG11 alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:103039495])

HSP 1 Score: 68.9366 bits (167), Expect = 4.248e-12
Identity = 80/298 (26.85%), Postives = 139/298 (46.64%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFT-ANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKL-RKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI 1192
            +YID +     +P+ + + G +V  Y H+P    DML  + +RN  F               K IY      +   + S +D+++ NS +T  ++     A  R S   +VYP  ++         L    E++ E      +S+ ++  +K+ +L + AF KL  K+  +    + +  +  GG  +   E+R +   L  L  +L + D   F L     D+K   ++ A+  L+T  NEHFGI  VE M     ++A  SGGP+  +V     G TGFL + D D+++E+M+R++
Sbjct:  169 LYIDSMGYAFTLPVFRYLGGCRVGSYVHYPTISTDMLNLVRERNPRFNNADYITNNPLLSAVKVIYYCAFALLYGLAGSCSDVVMVNSTWTLGHILALWRAPNRTS---VVYPPCDVQAF--LDVPLDEEEEQKGERKCHSLVSVAQFRPEKDHQLQIRAFRKLLDKKGAEPGGRESVKLMLIGGCRNQEDEDRVLM--LRGLCQELGVADRVEFKLNIPFEDLKKELVE-ATIGLHTMWNEHFGIGVVECMAAGTVILAHKSGGPKLDIVVPHDGGATGFLAD-DEDSYAEAMERIL 457
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Yeast
Match: ALG2 (Mannosyltransferase in the N-linked glycosylation pathway; catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol; human ALG2 complements the temperature sensitivity and dolichol-linked oligosaccharide biosynthesis defect of the alg2-1 mutant, but mutant form from a patient with CDG-Ii fails to complement [Source:SGD;Acc:S000003033])

HSP 1 Score: 264.618 bits (675), Expect = 1.964e-83
Identity = 152/368 (41.30%), Postives = 209/368 (56.79%), Query Frame = 2 
Query:  107 IAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILF-NFNDFDLIYIDQISAPIPLLKIFGFKVL-FYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCA----------------------FLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTG 1138
            IAF+HPDLGIGGAER +VDAA+ L+  G  V + T+H D SHCF+E KNG L V V G FLP +  GR    FA +R ++  + +IL    N + LI IDQ+S  IPLL IF    L FY HFPD LL++R G+ K+IYR+P D IE+FS+S AD ++ NS FT N + + F +   +DP ++YP  ++  +               E D   +LSINR+E KK++ L + AFA     L +   +D +  V  GGYD+ V EN +  + L  L  + E+ +                          L S ++ +K   L+R   LLYTP+ EHFGIVP+EAM L  PV+AVN+GGP ET+   + G
Sbjct:    9 IAFIHPDLGIGGAERLVVDAALGLQQQGHSVIIYTSHCDKSHCFEEVKNGQLKVEVYGDFLPTNFLGRFFIVFATIRQLYLVIQLILQKKVNAYQLIIIDQLSTCIPLLHIFSSATLMFYCHFPDQLLAQRAGLLKKIYRLPFDLIEQFSVSAADTVVVNSNFTKNTFHQTFKYLS-NDPDVIYPCVDLSTIEIEDIDKKFFKTVFNEGD-RFYLSINRFEKKKDVALAIKAFA-----LSEDQINDNVKLVICGGYDERVAENVEYLKELQSLADEYELSHTTIYYQEIKRVSDLESFKTNNSKIIFLTSISSSLKELLLERTEMLLYTPAYEHFGIVPLEAMKLGKPVLAVNNGGPLETIKSYVAG 369
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Nematostella
Match: EDO45087 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RTT6])

HSP 1 Score: 283.108 bits (723), Expect = 3.380e-91
Identity = 163/424 (38.44%), Postives = 235/424 (55.42%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFN-----FNDFDLI----------YIDQISAP----IPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNL------RSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            ++ F+HPDLGIGGAER +VDAA+ALK  G  V  +T HHD SHCF ETK+G LNV  VG +LPR   G   AF+AY+R+I+AA+Y++ F+     ++D  +I          Y + I +P    + L+ +     LFY  FP   L      FK +               AD++L NS FTA+ + + F   R S P ++YP  N ++             +PP  +        +FLSINRYE KKN+ L L A   LR  + +    +  L +  GGYD+ V EN+Q +  L  L     +      ++S + + K+  L     LLYTPSNEHFG+VP+EAMY + PVIAV SGGP ETV    TGFLC+ D ++F+++M++++  + LR+ LGEAG      +FSF+ F ++L  +V +
Sbjct:    3 RVVFIHPDLGIGGAERFVVDAALALKSKGHCVQFVTAHHDKSHCFKETKDGTLNVTAVGDWLPRQCLGHFYAFWAYVRMIYAAVYLVWFSGMVVVYDDICVIIINPLTYLHEYRNLIGSPTHYLLSLILLSQNPALFYFAFPKSCLVLMTIFFKGM---------------ADLVLVNSNFTADTFLKTFKTLRSSRPSVLYPSINFESFHIPFDHEEVKDLIPPTAKH-------VFLSINRYERKKNLPLALEALDWLRNTVSKEAWKETHLVIS-GGYDERVGENKQHYLELQALASKYNLSEKVTFIRSFSENQKLALLDFCCCLLYTPSNEHFGLVPIEAMYAERPVIAVKSGGPLETVSHNKTGFLCDPDAESFAKAMQKIVEGDKLRKSLGEAGRPHVMSKFSFEVFAEQLHTLVCQ 403
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Nematostella
Match: EDO27735 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T8F3])

HSP 1 Score: 114.005 bits (284), Expect = 1.741e-30
Identity = 52/106 (49.06%), Postives = 74/106 (69.81%), Query Frame = 2 
Query:  983 KVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            K+  L     LLYTPSNEHFG+VP+EAMY + PVIAV SGGP ETV    TGFLC+ D ++F+++M++++  + LR+ LGEAG      +FSF+ F ++L  +V +
Sbjct:    3 KLALLDFCCCLLYTPSNEHFGLVPIEAMYAERPVIAVKSGGPLETVSHNKTGFLCDPDAESFAKAMQKIVEGDKLRKSLGEAGRPHVMSKFSFEVFAEQLHTLVCQ 108
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Nematostella
Match: EDO34708 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SNN8])

HSP 1 Score: 63.1586 bits (152), Expect = 9.876e-11
Identity = 85/323 (26.32%), Postives = 135/323 (41.80%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DMLL-----------------SKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAK-LRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQ 1273
            IYID +     +PL K I G +V  Y H+P    DML                  S+   + K +Y     FI   +   AD+I+ NS +T       + +    +  IVYP  +  + +     LP       +      +SI ++  +K+  L L AFA+ L+ +   S    KL+ +  G   +    +R    NL +L   L I        + + D    F+  AS  L+T  NEHFGI  VE M     ++A  SGGP+  +V       TGFL  SD  +++ +M+ +   +   R +     + +   FS  AF+
Sbjct:  116 IYIDTMGYAFTMPLFKYIGGCQVGCYVHYPTISTDMLARVGSKESLYNNSSLISNSRLLSLIKLLYYYMFAFIYGMAGRCADVIMVNSSWTYG--HIMYLWKNYKNTSIVYPPCDTKSFQEIPICLP------QDGVIKTIISIGQFRPEKDHPLQLKAFAEFLKGQPKSSRSQYKLVLI--GSCRNQDDADR--VDNLRELAKSLSIRKHVDFALNVSFDELREFIGSASIGLHTMWNEHFGIGVVECMAGGIVMLAHESGGPKMDIVIEWEGKPTGFLA-SDEKSYASAMETIFSLQPEERSVICHNARSSVARFSESAFE 425
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Medaka
Match: alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase [Source:NCBI gene;Acc:101167069])

HSP 1 Score: 371.703 bits (953), Expect = 1.732e-125
Identity = 192/399 (48.12%), Postives = 258/399 (64.66%), Query Frame = 2 
Query:  104 KIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGF--KVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIV 1294
            ++ FLHPDLGIGGAER +VDAA+ALK  G  V + T H+D  HCF ET + DL VV  G +LP S+FG L A  AYLR+I+ A Y++  +  ++D+++ DQ+SA IP+LK+     KVLFY HFPD LL++R    K+ YR PID++E+ +   AD+I+ NS+FTA ++RE F         ++YP  N      SSA    +          LFLS+NRYE KKN+ L L A A LR  L    +    L V  GGYDD VTEN Q    L +L   L +++C   L+S ++ +KV  L+ ++A+LYTPS EHFGIVPVEAMY  CPVIAVNSGGP E+V  G TGFLCE   +AFS++M+RLI D +LRR++G+AG +R  ++FS +AF  +L   V
Sbjct:    3 RVVFLHPDLGIGGAERLVVDAAVALKSRGCSVQIWTAHYDPKHCFSETLDPDLPVVCAGDWLPTSVFGYLHALCAYLRMIYVAFYLVFLSTVEYDVVFCDQVSACIPVLKLSRHRKKVLFYCHFPDQLLTQRKSALKRFYRAPIDWLEERTTGMADMIVVNSQFTAGIFRETFQSLSTIQIDVLYPSLNTRAFDQSSAEAQGLGGLLPAGTSCLFLSLNRYERKKNLGLALEALAVLRCNLPPGQRAGVHLVVA-GGYDDRVTENIQHHTELKELAEQLHLEDCVTFLQSPSDSLKVALLRGSTAVLYTPSREHFGIVPVEAMYCCCPVIAVNSGGPLESVAHGETGFLCEPTAEAFSQAMERLIRDPHLRRDMGQAGRRRVKDKFSLEAFADQLHEYV 400
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Medaka
Match: ENSORLT00000010327.2 (GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:101159230])

HSP 1 Score: 70.0922 bits (170), Expect = 1.520e-12
Identity = 91/327 (27.83%), Postives = 150/327 (45.87%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--LSKRNGIF---------------KQIYRIPIDFIEKFSLSFADIILYNSEFT-ANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKL-RKELHQSDKHDKLLFVHFGGYDDLVTENR-QVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKR-LIVDENLRRELGEAGHQRACEEFSFKAFQ 1273
            +Y+D +     +P+ + + G KV  Y H+P    DML  +  RN  F               K +Y      +   + S +D+++ NS +T  ++     + +R S   IVYP  ++       A L   +EE  E+D    +S+ ++  +K+ +L + AF KL   +  +    + L  V  GG  +   E R Q  R L Q   +L + D   F L     ++K   +  A+  L+T  NEHFGI  VE M     V+A  SGGP+  +V    D  TGFL +S+ D+++ +M+  L +    R E+  A  Q +   FS + F+
Sbjct:  152 LYVDSMGYAFTLPIFRYLGGCKVASYVHYPTVSTDMLSVVRDRNPRFNNADFISRNPLLSTMKVVYYCCFALLYGLAGSCSDVVMVNSTWTLGHILALWRSPSRTS---IVYPPCDV------RAFLDVPLEEEDEDDGHTIVSVGQFRPEKDHQLQIRAFRKLLDGKGEEPAGRESLRLVLVGGCRNQEDEERVQTLRGLCQ---ELGVADRVQFKLNVPFEELKRELVS-ATIGLHTMWNEHFGIGVVECMAAGTIVLAHKSGGPKLDIVVPYDDRQTGFLADSE-DSYAAAMETILALSPAARLEIRRAARQ-SVSRFSDQEFE 463
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Medaka
Match: alg11 (GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:101175546])

HSP 1 Score: 63.929 bits (154), Expect = 1.395e-10
Identity = 85/328 (25.91%), Postives = 144/328 (43.90%), Query Frame = 2 
Query:  392 IYIDQISAP--IPLLK-IFGFKVLFYAHFP----DML--LSKRN---------------GIFKQIYRIPIDFIEKFSLSFADIILYNSEFTAN----VYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAK-LRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQ 1273
            +YID +     +PL + + G +V  Y H+P    DML  + +RN                 FK +Y      +   + S +D+ + NS +T N    ++R        +   +VYP  ++     +   +P   E+         +S+ ++  +K+ +L + AF K L +        + L  V  GG  +   E R +   L  L  +L + D   F L     D+K   +  A+  L+T  NEHFGI  VE M     V+A NSGGP+  +V     G TGFL  SD D+++++++R++      R       +++   FS + FQ
Sbjct:  174 LYIDSMGYAFTLPLFRYLGGCRVGTYLHYPTVSTDMLSVVRERNPRFNNPDYISNSLFLSAFKVVYYFLFALLYGMAGSCSDLTMVNSSWTLNHILSLWRSP------NRTCLVYPPCDV----GAFLDIPLEEEDGGGRKSHSLVSVGQFRPEKDHQLQIRAFKKVLDRRRAALGGEEALKLVLIGGCRNQEDEERVLM--LRGLCQELGVADKVEFKLNISFEDLKKE-IGEATIGLHTMWNEHFGIGVVECMAAGKVVLAHNSGGPKLDIVVPFEGGQTGFL-ASDEDSYADAIERILALPAADRLRIRRNARQSAARFSDEEFQ 487
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Medaka
Match: ENSORLT00000044749.1 (GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Source:NCBI gene;Acc:101159230])

HSP 1 Score: 53.9138 bits (128), Expect = 2.494e-7
Identity = 56/185 (30.27%), Postives = 92/185 (49.73%), Query Frame = 2 
Query:  743 LSINRYEHKKNIELGLLAFAKL-RKELHQSDKHDKLLFVHFGGYDDLVTENR-QVFRNLNQLIIDLEI-DNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVV----DGLTGFLCESDPDAFSESMKRLI-VDENLRRELGEAGHQRACEEFSFKAFQ 1273
            +S+ ++  +K+ +L + AF KL   +  +    + L  V  GG  +   E R Q  R L Q   +L + D   F L     ++K   +  A+  L+T  NEHFGI  VE M     V+A  SGGP+  +V    D  TGFL +S+ D+++ +M+ ++ +    R E+  A  Q +   FS + F+
Sbjct:  330 VSVGQFRPEKDHQLQIRAFRKLLDGKGEEPAGRESLRLVLVGGCRNQEDEERVQTLRGLCQ---ELGVADRVQFKLNVPFEELKRELVS-ATIGLHTMWNEHFGIGVVECMAAGTIVLAHKSGGPKLDIVVPYDDRQTGFLADSE-DSYAAAMETILALSPAARLEIRRAARQ-SVSRFSDQEFE 508
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Planmine SMEST
Match: SMESG000043780.1 (SMESG000043780.1)

HSP 1 Score: 813.913 bits (2101), Expect = 0.000e+0
Identity = 399/403 (99.01%), Postives = 401/403 (99.50%), Query Frame = 2 
Query:   92 MMNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            MMNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEK SLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKE HQSDKHDKL+FVHFGGYDDLVTENR+VFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE
Sbjct:    1 MMNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKISLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKEFHQSDKHDKLIFVHFGGYDDLVTENRKVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 403
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Planmine SMEST
Match: SMESG000043780.1 (SMESG000043780.1)

HSP 1 Score: 811.216 bits (2094), Expect = 0.000e+0
Identity = 398/402 (99.00%), Postives = 400/402 (99.50%), Query Frame = 2 
Query:   95 MNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 1300
            MNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEK SLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKE HQSDKHDKL+FVHFGGYDDLVTENR+VFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE
Sbjct:    1 MNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDLIYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIEKISLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKEFHQSDKHDKLIFVHFGGYDDLVTENRKVFRNLNQLIIDLEIDNCAFLLKSCANDVKVNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGFLCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNIVSE 402
[Close]
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Planmine SMEST
Match: SMESG000037330.1 (SMESG000037330.1)

HSP 1 Score: 50.0618 bits (118), Expect = 2.340e-6
Identity = 93/399 (23.31%), Postives = 164/399 (41.10%), Query Frame = 2 
Query:  107 IAFLHPDL-GIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFDETKNGDLNVVVVGQFLPRSI-FGRL--CAF-----FAYLRLIFAALYIILFNFNDFDL----IYIDQISAPI--PLLKIFGF-KVLFYAHFP----DMLLS--------KRNGIFK--QIYR-IPIDFIEKFSLSF------ADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNI-------DNLRSSSASLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAK-LRKELHQSDK--HDKLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVK--VNFLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVD-GLTGFLCES 1153
            +AF HP   G GG ER + +    ++ N F       + +     D++   ++N++  G  + + I F RL  C       +    +I  ++  IL      +     +Y D +      P+ K  G  K + Y H+P    DMLLS          N + K  Q+Y  + + +   F+  +       D ++ NS +T    + H +     +  ++YP  ++       +NL + S   P II            S+ ++  +K+  L L AF + +    H  +K   D +  V  GG     +E++   + L      L I   +++   C  + K  ++  +     L+T  NEHFGI  VE M      +  NSGGP+  ++D G+ GFL  +
Sbjct:   48 VAFFHPSCNGGGGGERVLWEGIKVIQ-NKFPKAFCVVYCNDILSSDDSILENVNIIF-GIRIEKPIQFIRLNYCGLLEPSKYKRFTMIGQSIGSILVGLEAINKCVPNVYFDTVGYAFTFPIFKCLGLCKTVAYIHYPTISSDMLLSVTNREISVNNNSLVKNSQLYTYLKVYYYRSFAFLYFLVSKAVDCVIVNSSWT----KSHISSIWGREVKVIYPPCDVAKIKFYFNNLTTKSRKRPWII------------SVGQFRPEKDHLLQLEAFKQFIDNYKHNVNKMYEDDIKLVLIGGCRS--SEDKNRVKYLQSKCEQLNIQ--SYVKFKCNINYKEMLHCFEEGLIGLHTMKNEHFGIAIVEYMAAGMIPVVHNSGGPKLDIIDHGINGFLATT 424
The following BLAST results are available for this feature:
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ALG22.111e-11142.26ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGN... [more]
ALG24.098e-7641.31ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGN... [more]
ALG22.732e-2543.33ALG2 alpha-1,3/1,6-mannosyltransferase [Source:HGN... [more]
ALG119.081e-1527.86ALG11 alpha-1,2-mannosyltransferase [Source:HGNC S... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3
Match NameE-valueIdentityDescription
algn-22.284e-9944.64Asparagine Linked Glycosylation (ALG) homolog, Nem... [more]
bus-85.972e-3227.67Glycosyltransferase [Source:UniProtKB/TrEMBL;Acc:... [more]
bus-85.972e-3227.67Glycosyltransferase [Source:UniProtKB/TrEMBL;Acc:... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 3
Match NameE-valueIdentityDescription
Alg28.751e-11144.42gene:FBgn0035401 transcript:FBtr0073023[more]
Alg113.233e-824.93gene:FBgn0037108 transcript:FBtr0078422[more]
Alg113.233e-824.93gene:FBgn0037108 transcript:FBtr0333392[more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
alg21.389e-11744.91ALG2 alpha-1,3/1,6-mannosyltransferase [Source:ZFI... [more]
alg21.680e-5139.75ALG2 alpha-1,3/1,6-mannosyltransferase [Source:ZFI... [more]
alg113.757e-1225.71ALG11 alpha-1,2-mannosyltransferase [Source:NCBI g... [more]
alg117.329e-1225.71ALG11 alpha-1,2-mannosyltransferase [Source:NCBI g... [more]
alg117.329e-1225.71ALG11 alpha-1,2-mannosyltransferase [Source:NCBI g... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 3
Match NameE-valueIdentityDescription
kif3a4.251e-11743.36kinesin family member 3A [Source:Xenbase;Acc:XB-GE... [more]
alg113.499e-727.74ALG11, alpha-1,2-mannosyltransferase [Source:NCBI ... [more]
alg114.761e-727.74ALG11, alpha-1,2-mannosyltransferase [Source:NCBI ... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Alg23.815e-11343.92asparagine-linked glycosylation 2 (alpha-1,3-manno... [more]
Alg21.180e-2837.72asparagine-linked glycosylation 2 (alpha-1,3-manno... [more]
Alg112.110e-1529.39asparagine-linked glycosylation 11 (alpha-1,2-mann... [more]
Alg112.793e-1529.39asparagine-linked glycosylation 11 (alpha-1,2-mann... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9DBE8|ALG2_MOUSE2.669e-11243.92Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Mus musc... [more]
sp|Q9H553|ALG2_HUMAN1.014e-11042.26Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Homo sap... [more]
sp|O94738|ALG2_RHIPU1.164e-10141.25Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Rhizomuc... [more]
sp|Q7KWM5|ALG2_DICDI9.151e-10143.45Alpha-1,3/1,6-mannosyltransferase ALG2 OS=Dictyost... [more]
sp|Q96WW6|ALG2_SCHPO8.928e-8840.10Alpha-1,3/1,6-mannosyltransferase alg2 OS=Schizosa... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
T1EF462.309e-13248.88Uncharacterized protein OS=Helobdella robusta OX=6... [more]
K1PCW53.684e-13148.61Alpha-1,3-mannosyltransferase ALG2 OS=Crassostrea ... [more]
A0A3Q8C0P96.376e-12950.12Alpha-1,3/1,6-mannosyltransferase OS=Locusta migra... [more]
A0A1S3IJT32.788e-12846.73alpha-1,3/1,6-mannosyltransferase ALG2 OS=Lingula ... [more]
A0A1S3HHC29.315e-12846.73alpha-1,3/1,6-mannosyltransferase ALG2-like OS=Lin... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
alg24.548e-11545.00ALG2 alpha-1,3/1,6-mannosyltransferase [Source:NCB... [more]
alg113.847e-1226.85ALG11 alpha-1,2-mannosyltransferase [Source:NCBI g... [more]
alg114.029e-1225.12ALG11 alpha-1,2-mannosyltransferase [Source:NCBI g... [more]
alg114.248e-1226.85ALG11 alpha-1,2-mannosyltransferase [Source:NCBI g... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
ALG21.964e-8341.30Mannosyltransferase in the N-linked glycosylation ... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO450873.380e-9138.44Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO277351.741e-3049.06Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO347089.876e-1126.32Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4
Match NameE-valueIdentityDescription
alg21.732e-12548.12ALG2 alpha-1,3/1,6-mannosyltransferase [Source:NCB... [more]
ENSORLT00000010327.21.520e-1227.83GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosylt... [more]
alg111.395e-1025.91GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosylt... [more]
ENSORLT00000044749.12.494e-730.27GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosylt... [more]
back to top
BLAST of alpha-1,3/1,6-mannosyltransferase ALG2 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000043780.10.000e+099.01SMESG000043780.1[more]
SMESG000043780.10.000e+099.00SMESG000043780.1[more]
SMESG000037330.12.340e-623.31SMESG000037330.1[more]
back to top
Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035589 ID=SMED30035589|Name=alpha-1,3/1,6-mannosyltransferase ALG2|organism=Schmidtea mediterranea sexual|type=transcript|length=1419bp
CACTAACTTAATAATTCAAATTTAATTTTTTTCGCTTTTAAATTACAGAA
ATTTTTTAAAAATATATTTCATCGACATCTTTATATTATAAATGATGAAT
AATAAAATAGCTTTTTTACATCCTGATCTAGGCATAGGTGGTGCTGAGCG
TGCTATAGTAGACGCAGCTATGGCTTTAAAATTAAATGGATTTAAAGTAA
CTATGATCACTAATCATCATGATGCTAGTCATTGTTTTGATGAGACAAAG
AATGGTGATCTTAATGTCGTAGTAGTTGGACAATTTTTACCTAGATCTAT
TTTCGGACGTTTGTGTGCATTTTTTGCATACTTGCGTTTAATATTTGCTG
CTTTATATATAATCCTTTTCAATTTTAACGACTTTGATTTAATTTACATT
GACCAAATATCAGCTCCCATTCCATTACTTAAGATATTTGGATTTAAAGT
TTTATTTTATGCGCATTTTCCAGATATGTTATTATCCAAACGAAACGGAA
TATTTAAACAGATTTACAGGATACCAATTGATTTTATTGAAAAATTTTCT
CTTTCATTTGCAGATATTATCCTGTATAATAGTGAATTTACAGCAAACGT
TTACCGAGAGCATTTTGCCTTCACCCGTCTCTCGGATCCCCTCATCGTTT
ACCCGGTGCCAAATATCGATAATTTGCGCTCCTCATCTGCCTCGTTGCCA
CCAATTATTGAGGAGAGAATGGAAAATGATTTCATTTTATTCCTCTCGAT
CAATCGATACGAGCACAAGAAAAATATTGAATTGGGCTTGCTAGCGTTCG
CAAAATTGCGGAAGGAATTACATCAATCTGACAAACACGACAAATTGTTA
TTTGTGCATTTCGGTGGCTATGACGATCTCGTTACGGAGAATCGCCAAGT
TTTCCGCAATCTGAATCAGTTAATTATCGATTTGGAGATTGATAATTGTG
CATTCTTGCTGAAATCGTGTGCCAATGACGTCAAGGTGAATTTCCTGAAG
CGAGCAAGTGCGTTATTGTACACTCCATCCAATGAACACTTTGGCATAGT
GCCGGTTGAAGCGATGTACCTGAAATGTCCTGTTATTGCTGTGAATAGCG
GCGGCCCTAGGGAAACTGTTGTTGATGGGTTGACTGGGTTTCTGTGTGAA
TCTGATCCTGATGCTTTCTCTGAGTCAATGAAACGGCTGATTGTTGATGA
GAATCTCCGTCGCGAACTCGGGGAAGCAGGACATCAGCGAGCTTGTGAAG
AATTTTCTTTCAAGGCCTTTCAGAAAAAATTATCAAATATTGTCAGTGAG
CTGATTCAATAAAGTGGAATATTTTTACAATAAATAATTTTGTCTTTTCT
TATTCGTGTGTGATGAGAAGGTTGTTTGTGACGCTGTCAGTATTGGGGAT
TTTTCTTTTTGAATTTGTG
back to top

protein sequence of SMED30035589-orf-1

>SMED30035589-orf-1 ID=SMED30035589-orf-1|Name=SMED30035589-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=407bp
MMNNKIAFLHPDLGIGGAERAIVDAAMALKLNGFKVTMITNHHDASHCFD
ETKNGDLNVVVVGQFLPRSIFGRLCAFFAYLRLIFAALYIILFNFNDFDL
IYIDQISAPIPLLKIFGFKVLFYAHFPDMLLSKRNGIFKQIYRIPIDFIE
KFSLSFADIILYNSEFTANVYREHFAFTRLSDPLIVYPVPNIDNLRSSSA
SLPPIIEERMENDFILFLSINRYEHKKNIELGLLAFAKLRKELHQSDKHD
KLLFVHFGGYDDLVTENRQVFRNLNQLIIDLEIDNCAFLLKSCANDVKVN
FLKRASALLYTPSNEHFGIVPVEAMYLKCPVIAVNSGGPRETVVDGLTGF
LCESDPDAFSESMKRLIVDENLRRELGEAGHQRACEEFSFKAFQKKLSNI
VSELIQ*
back to top
Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0004378GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity
GO:0016740transferase activity
GO:0016757transferase activity, transferring glycosyl groups
Vocabulary: biological process
TermDefinition
GO:0006486protein glycosylation
GO:0097502mannosylation
Vocabulary: INTERPRO
TermDefinition
IPR027054ALG2
IPR001296Glyco_trans_1
IPR028098Glyco_trans_4-like_N
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001296Glycosyl transferase, family 1PFAMPF00534Glycos_transf_1coord: 213..382
e-value: 3.0E-32
score: 111.5
IPR028098Glycosyltransferase subfamily 4-like, N-terminal domainPFAMPF13439Glyco_transf_4coord: 15..179
e-value: 1.2E-11
score: 44.9
NoneNo IPR availableGENE3DG3DSA:3.40.50.2000coord: 198..389
e-value: 3.5E-41
score: 143.1
NoneNo IPR availableGENE3DG3DSA:3.40.50.2000coord: 2..194
e-value: 1.3E-11
score: 46.6
NoneNo IPR availablePANTHERPTHR45918:SF1ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2coord: 3..405
NoneNo IPR availableCDDcd03805GT4_ALG2-likecoord: 5..397
e-value: 4.67749E-172
score: 484.4
NoneNo IPR availableSUPERFAMILYSSF53756UDP-Glycosyltransferase/glycogen phosphorylasecoord: 4..405
NoneNo IPR availableTMHMMTMhelixcoord: 70..92
IPR027054Mannosyltransferase ALG2PANTHERPTHR45918FAMILY NOT NAMEDcoord: 3..405