Serine/threonine protein kinase, putative
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035587 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 50Note: Hover over icons to view figure legend
Homology
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 77.411 bits (189), Expect = 1.367e-14 Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P + + FK ID+CLN+DP+ R + + LL++KF Sbjct: 43 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 196
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 77.0258 bits (188), Expect = 2.689e-14 Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P + + FK ID+CLN+DP+ R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 77.411 bits (189), Expect = 2.931e-14 Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P + + FK ID+CLN+DP+ R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404]) HSP 1 Score: 73.1738 bits (178), Expect = 3.108e-14 Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P ++ FK +++CLN+DP R + + LL++KF Sbjct: 28 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 175
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174]) HSP 1 Score: 77.411 bits (189), Expect = 3.256e-14 Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P + + FK ID+CLN+DP+ R + + LL++KF Sbjct: 142 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 295
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3]) HSP 1 Score: 73.1738 bits (178), Expect = 6.468e-14 Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ L+ L LH H IV+ ++ ++LL G++KL + +I PG KR+ + +++PEIL+ K +N K D+WS GI+ LE+I G E + + K I+ ++ N + F +D CL DP+ R LL + F Sbjct: 101 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 249
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3]) HSP 1 Score: 72.7886 bits (177), Expect = 3.077e-13 Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ L+ L LH H IV+ ++ ++LL G++KL + +I PG KR+ + +++PEIL+ K +N K D+WS GI+ LE+I G E + + K I+ ++ N + F +D CL DP+ R LL + F Sbjct: 258 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 406
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3]) HSP 1 Score: 72.7886 bits (177), Expect = 4.797e-13 Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ L+ L LH H IV+ ++ ++LL G++KL + +I PG KR+ + +++PEIL+ K +N K D+WS GI+ LE+I G E + + K I+ ++ N + F +D CL DP+ R LL + F Sbjct: 430 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 578
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3]) HSP 1 Score: 72.7886 bits (177), Expect = 4.862e-13 Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ L+ L LH H IV+ ++ ++LL G++KL + +I PG KR+ + +++PEIL+ K +N K D+WS GI+ LE+I G E + + K I+ ++ N + F +D CL DP+ R LL + F Sbjct: 433 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 581
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3]) HSP 1 Score: 72.7886 bits (177), Expect = 5.393e-13 Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ L+ L LH H IV+ ++ ++LL G++KL + +I PG KR+ + +++PEIL+ K +N K D+WS GI+ LE+I G E + + K I+ ++ N + F +D CL DP+ R LL + F Sbjct: 481 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 629
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: inaC (gene:FBgn0004784 transcript:FBtr0087047) HSP 1 Score: 78.5666 bits (192), Expect = 1.152e-14 Identity = 45/135 (33.33%), Postives = 73/135 (54.07%), Query Frame = 1 Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNE----INKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-IDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962 LH+ I+Y +L + +ILLD +G +KL + K +++ +Y+APEI+ P++I AD WSFG++L E + G+ A E +E+ F+ I KK +FP + +I S L + PNNR+ Sbjct: 486 LHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ-----APFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGA 615
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399) HSP 1 Score: 75.8702 bits (185), Expect = 7.000e-14 Identity = 46/163 (28.22%), Postives = 83/163 (50.92%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP--------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R++L+GL LH ++ ++ +++LL +GD+KLA + GQ N +K ++APE++ ++ KAD+WS GI +E+ G+ N +E H ++ ++ P S + FK +++CLN+DP NR + + LL+ F Sbjct: 115 REVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVA----GQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPN--------SELHPMRV---LFLIPKNNPPQLTGSYTKSFKDFVEACLNKDPENRPTAKELLKYPF 262
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0303432) HSP 1 Score: 74.7146 bits (182), Expect = 1.325e-13 Identity = 43/139 (30.94%), Postives = 77/139 (55.40%), Query Frame = 1 Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC-FNFSAKTEAKN---ESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISV 1962 LH+ GI+Y +L + ++LLD +G IKL + K I PG + +Y+APEIL + + D W+ G++L E++ G+ F+ + +E + E + F++ +K I P S++ R V+ LN++P +R+ Sbjct: 297 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC 435
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0329888) HSP 1 Score: 74.7146 bits (182), Expect = 1.377e-13 Identity = 43/139 (30.94%), Postives = 77/139 (55.40%), Query Frame = 1 Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC-FNFSAKTEAKN---ESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISV 1962 LH+ GI+Y +L + ++LLD +G IKL + K I PG + +Y+APEIL + + D W+ G++L E++ G+ F+ + +E + E + F++ +K I P S++ R V+ LN++P +R+ Sbjct: 292 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC 430
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0303429) HSP 1 Score: 74.7146 bits (182), Expect = 1.403e-13 Identity = 43/139 (30.94%), Postives = 77/139 (55.40%), Query Frame = 1 Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC-FNFSAKTEAKN---ESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISV 1962 LH+ GI+Y +L + ++LLD +G IKL + K I PG + +Y+APEIL + + D W+ G++L E++ G+ F+ + +E + E + F++ +K I P S++ R V+ LN++P +R+ Sbjct: 297 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC 435
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537]) HSP 1 Score: 76.6406 bits (187), Expect = 1.578e-14 Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P S ++ FK +++CLN+DP R + + LL++KF Sbjct: 33 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 180
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537]) HSP 1 Score: 77.411 bits (189), Expect = 1.680e-14 Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P S ++ FK +++CLN+DP R + + LL++KF Sbjct: 122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk26 (serine/threonine protein kinase 26 [Source:ZFIN;Acc:ZDB-GENE-080516-5]) HSP 1 Score: 74.3294 bits (181), Expect = 1.378e-13 Identity = 46/163 (28.22%), Postives = 81/163 (49.69%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL G++KLA + G++ Q + E ++APE++ ++ KAD+WS GI +E+ G+ N KN D+ K FK +DSCLN+DP R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGDFSKI---------FKEFVDSCLNKDPAFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk24a (serine/threonine kinase 24a (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-070424-52]) HSP 1 Score: 74.3294 bits (181), Expect = 1.644e-13 Identity = 49/161 (30.43%), Postives = 84/161 (52.17%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSI----NERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ AK E + K +F P ++ N+ K +D+CLN+DPN R + + LL++K Sbjct: 119 REILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSEYDSKADIWSLGITAIEL-------------AKGEPPHSDLHPMKVLFLIPKENPPTLEGNYNKALKEFVDACLNKDPNFRPTAKELLKHKL 266
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: map2k7 (mitogen-activated protein kinase kinase 7 [Source:ZFIN;Acc:ZDB-GENE-090312-186]) HSP 1 Score: 74.3294 bits (181), Expect = 1.738e-13 Identity = 58/191 (30.37%), Postives = 98/191 (51.31%), Query Frame = 1 Query: 1441 VSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHD-HGIVYDELTMSHILLDSKGDIKLASINI-GKII--PGQKRNEINKDYLAPEILD----NKP-WNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 V ++MELM ++ K + G A + K I+ L L + HG+++ ++ S+ILLD+KG IKL I G+++ + R+ Y+APE +D +KP ++I+ADVWS GI L+E+ TG+ + KT+ + + + D + + F+ + CL +D R LLE+ F Sbjct: 200 VFIAMELMGTCAEKLKKRIQGPIPEAI---LGKMTVAIVNALLYLKEKHGVIHRDVKPSNILLDAKGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPSKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEDPPVLPLSMGFSPDFQSFVKDCLTKDHRKRPKYHKLLEHSF 387
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 78.5666 bits (192), Expect = 7.644e-15 Identity = 48/161 (29.81%), Postives = 86/161 (53.42%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSINER----FKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ AK E + + + +F P S+ + FK +++CLN+DP +R + R LL+++F Sbjct: 109 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-------------AKGEPPYSDLHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELLKHRF 256
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 78.5666 bits (192), Expect = 8.399e-15 Identity = 48/161 (29.81%), Postives = 86/161 (53.42%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSINER----FKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ AK E + + + +F P S+ + FK +++CLN+DP +R + R LL+++F Sbjct: 109 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-------------AKGEPPYSDLHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELLKHRF 256
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355]) HSP 1 Score: 78.5666 bits (192), Expect = 9.664e-15 Identity = 48/161 (29.81%), Postives = 86/161 (53.42%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSINER----FKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ AK E + + + +F P S+ + FK +++CLN+DP +R + R LL+++F Sbjct: 109 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-------------AKGEPPYSDLHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELLKHRF 256
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: cpvl (carboxypeptidase, vitellogenic-like [Source:Xenbase;Acc:XB-GENE-1014879]) HSP 1 Score: 78.5666 bits (192), Expect = 1.106e-14 Identity = 51/171 (29.82%), Postives = 87/171 (50.88%), Query Frame = 1 Query: 1510 RIASNDE--VIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+ DE + ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N KN D+ K FK +D+CLN+DP+ R + R LL++K+ Sbjct: 112 RVGPFDEFQIATMLKEILKGLDYLHSENKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPSLTGDFSK---------PFKEFVDACLNKDPSFRPTARELLKHKY 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: cpvl (carboxypeptidase, vitellogenic-like [Source:Xenbase;Acc:XB-GENE-1014879]) HSP 1 Score: 78.1814 bits (191), Expect = 1.110e-14 Identity = 51/171 (29.82%), Postives = 87/171 (50.88%), Query Frame = 1 Query: 1510 RIASNDE--VIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+ DE + ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N KN D+ K FK +D+CLN+DP+ R + R LL++K+ Sbjct: 100 RVGPFDEFQIATMLKEILKGLDYLHSENKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPSLTGDFSK---------PFKEFVDACLNKDPSFRPTARELLKHKY 261
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 77.411 bits (189), Expect = 1.582e-14 Identity = 49/162 (30.25%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P I + FK ID+CLN+DP+ R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665]) HSP 1 Score: 77.411 bits (189), Expect = 1.749e-14 Identity = 49/162 (30.25%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P I + FK ID+CLN+DP+ R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Stk25 (serine/threonine kinase 25 (yeast) [Source:MGI Symbol;Acc:MGI:1891699]) HSP 1 Score: 73.1738 bits (178), Expect = 4.445e-13 Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P ++ FK +++CLN+DP R + + LL++KF Sbjct: 122 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Prkci (protein kinase C, iota [Source:MGI Symbol;Acc:MGI:99260]) HSP 1 Score: 73.9442 bits (180), Expect = 4.458e-13 Identity = 42/140 (30.00%), Postives = 74/140 (52.86%), Query Frame = 1 Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC----FNFSAKTEAKNESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISVR 1965 LH+ GI+Y +L + ++LLDS+G IKL + K + PG + +Y+APEIL + + D W+ G+++ E++ G+ S + E + F++ +K I P S++ + V+ S LN+DP R+ Sbjct: 368 LHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCH 507
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Prkcd (protein kinase C, delta [Source:MGI Symbol;Acc:MGI:97598]) HSP 1 Score: 73.1738 bits (178), Expect = 6.871e-13 Identity = 45/145 (31.03%), Postives = 74/145 (51.03%), Query Frame = 1 Query: 1549 QILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKI-IPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFF---KIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962 +I+ GL LH GI+Y +L + +++LD G IK+A + K I G+ R DY+APEIL ++ D WSFG++L E++ G+ + +E F ++D Y P I + K +++ DP+ R+ V Sbjct: 339 EIICGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQ-----SPFHGDDEDELFESIRVDTPHY--PRWITKESKDIMEKLFERDPDKRLGV 476
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q9S7U9|M2K2_ARATH (Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2) HSP 1 Score: 77.411 bits (189), Expect = 9.546e-14 Identity = 51/196 (26.02%), Postives = 101/196 (51.53%), Query Frame = 1 Query: 1435 GLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLH-DHGIVYDELTMSHILLDSKGDIKLASINIGKII---PGQKRNEINK-DYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-----IDYKKYIFPVS-INERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 G +S+ +E M SL + K+V + + + +RQ+L+GL LH D I++ +L S++L++ +G++K+ + ++ G + +Y++PE + + K+D+WS G+++LE TGK F ++ + + + F+ +D P + I +CL +DPN+R S + L+E+ F Sbjct: 139 GAISLILEYMDGGSLADFLKSV----KAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECATGK-FPYAPPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQKDPNSRSSAKELMEHPF 329
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q99JT2|STK26_MOUSE (Serine/threonine-protein kinase 26 OS=Mus musculus OX=10090 GN=Stk26 PE=1 SV=1) HSP 1 Score: 77.411 bits (189), Expect = 1.106e-13 Identity = 49/162 (30.25%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P I + FK ID+CLN+DP+ R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|P13677|KPC2_DROME (Protein kinase C, eye isozyme OS=Drosophila melanogaster OX=7227 GN=inaC PE=1 SV=1) HSP 1 Score: 78.5666 bits (192), Expect = 1.155e-13 Identity = 45/135 (33.33%), Postives = 73/135 (54.07%), Query Frame = 1 Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNE----INKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-IDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962 LH+ I+Y +L + +ILLD +G +KL + K +++ +Y+APEI+ P++I AD WSFG++L E + G+ A E +E+ F+ I KK +FP + +I S L + PNNR+ Sbjct: 486 LHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ-----APFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGA 615
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q9P289|STK26_HUMAN (Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2) HSP 1 Score: 77.411 bits (189), Expect = 1.408e-13 Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P + + FK ID+CLN+DP+ R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q55GC2|DST2_DICDI (Serine/threonine-protein kinase dst2 OS=Dictyostelium discoideum OX=44689 GN=dst2 PE=3 SV=1) HSP 1 Score: 78.1814 bits (191), Expect = 1.999e-13 Identity = 54/162 (33.33%), Postives = 86/162 (53.09%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNE-INKDY-LAPEILDNK----PWNIKADVWSFGIILLEIITGKCFNFSAKTEAK-NESHFFKIDYK-KYIFPVSINER------FKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+ L+GL LH +++ +L ++ILL GD+KLA + G + KRN I Y +APE+++N+ P++ KAD+WS GI L+E+ A+ E +E H K+ ++ Y P + + F I SCL +DPN R + LL++ F Sbjct: 123 RETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIEL---------AEAEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPF 275
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: A0A371IGI6 (Mitogen-activated protein kinase kinase kinase NPK1 (Fragment) OS=Mucuna pruriens OX=157652 GN=NPK1 PE=3 SV=1) HSP 1 Score: 89.7373 bits (221), Expect = 1.621e-15 Identity = 67/225 (29.78%), Postives = 115/225 (51.11%), Query Frame = 1 Query: 1339 INNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWY-RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIP--GQKRNEINKD--YLAPEILDNKPWNIKADVWSFGIILLEIITGK---CFNFSAK-TEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 + +L KE++ L +N+S V+ I + +G +++ ME MA V K + +++V++ Y R+IL G+ LH HGIV+ +L +++LL S G+IKLA K + I ++APE+L N+ + AD+WS G ++E+ TGK S T N +H +I + FP ++ + C++ +P NR +V+ LL + F Sbjct: 50 VGRDALDKEIKILRTLNSSPYIVQCLGIQEDQGKLNIFMEYMA---GGSLADVAHKFGGSLDEKVVRIYTREILHGINHLHQHGIVHCDLKCNNVLLGSSGNIKLADFGCAKRVKDLANSWQSIGGTPLWMAPEVLRNESLDFAADIWSLGCTVIEMATGKPPWANQLSNPITAVLNIAHGDRIPH----FPSHFSKDGLDFLSRCMDREPKNRSTVKELLCHPF 267
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: C4M8G8 (Serine/threonine protein kinase, putative OS=Entamoeba histolytica OX=5759 GN=EHI_063010 PE=4 SV=1) HSP 1 Score: 92.4337 bits (228), Expect = 2.522e-15 Identity = 67/235 (28.51%), Postives = 116/235 (49.36%), Query Frame = 1 Query: 1339 INNSSLIKE-------LRKLTVMNASERFVRIFAIYKGEGLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKI---DYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 +N S++KE L+KL + VR A + G + + ME M + SL K + S K+ Q+L+GLA +HD GIV+ ++ ++IL+ G +K+A + + G ++ E D ++APE++ + +KAD+W+ G ++E+ITG + A +KI DY FP +++ + + ++ SC DPN R S R LL++K+ Sbjct: 35 VNKKSVMKEVMEEIRLLKKL----KHKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLS----AKYIHQVLDGLAFIHDQGIVHRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGSDEDPIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELITGNPPYYDLNPTAA----LYKIVNDDYPP--FPNTVSPQLREILFSCFKRDPNQRASSRDLLKHKW 255
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: A0A5K1UP00 (Serine threonine protein kinase putative OS=Entamoeba histolytica OX=5759 GN=CL6EHI_063010 PE=4 SV=1) HSP 1 Score: 92.4337 bits (228), Expect = 2.522e-15 Identity = 67/235 (28.51%), Postives = 116/235 (49.36%), Query Frame = 1 Query: 1339 INNSSLIKE-------LRKLTVMNASERFVRIFAIYKGEGLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKI---DYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 +N S++KE L+KL + VR A + G + + ME M + SL K + S K+ Q+L+GLA +HD GIV+ ++ ++IL+ G +K+A + + G ++ E D ++APE++ + +KAD+W+ G ++E+ITG + A +KI DY FP +++ + + ++ SC DPN R S R LL++K+ Sbjct: 35 VNKKSVMKEVMEEIRLLKKL----KHKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLS----AKYIHQVLDGLAFIHDQGIVHRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGSDEDPIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELITGNPPYYDLNPTAA----LYKIVNDDYPP--FPNTVSPQLREILFSCFKRDPNQRASSRDLLKHKW 255
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: A0A4P9XQV2 (Kinase-like domain-containing protein (Fragment) OS=Thamnocephalis sphaerospora OX=78915 GN=THASP1DRAFT_2332 PE=3 SV=1) HSP 1 Score: 86.6557 bits (213), Expect = 4.736e-15 Identity = 59/227 (25.99%), Postives = 114/227 (50.22%), Query Frame = 1 Query: 1327 WKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAV--DGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKII----PGQKRNEIN-KDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 WK +N ++ LR V+ R++ ++ V + MEL + E F + +G+ R + RQ++ GL LH HG+++ +L +S++LL + +KL + ++ P ++R +Y+APE+L ++P+ ++D+WS G IL+ ++TG+ F ++ A+ I Y P S++ + + L +DP+ RIS++ L + F Sbjct: 47 WKRVVNEVTIHLRLRHPAVL-------RLYDCFEDADHVYLVMEL--CTGGELFGQLHRNGRRRRLTEARTRDIMRQLISGLMYLHAHGVLHRDLKLSNVLLTADHRVKLGDFGLATLLRANRPDERRTLCGTPNYIAPEVLAHEPYGFESDIWSLGCILVALLTGRG-PFEGQSTAET---LDNIRNCTYSLPGSMSVASRDLARRFLQKDPHRRISLQKALLHPF 260
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: K2HFC6 (Serine/threonine protein kinase, putative OS=Entamoeba nuttalli (strain P19) OX=1076696 GN=ENU1_052280 PE=4 SV=1) HSP 1 Score: 89.7373 bits (221), Expect = 1.729e-14 Identity = 66/235 (28.09%), Postives = 114/235 (48.51%), Query Frame = 1 Query: 1339 INNSSLIKE-------LRKLTVMNASERFVRIFAIYKGEGLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKI---DYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 +N S++KE L+KL + VR A + G + + ME M + SL K + S K+ Q+L+GL +HD GIV+ ++ ++IL+ G +K+A + + G ++ E D ++APE++ + +KAD+W+ G ++E+ITG + A +KI DY FP +++ + + + SC DPN R S R LL++K+ Sbjct: 295 VNKKSVMKEVMEEIRLLKKL----KHKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLS----AKYIHQVLDGLTFIHDQGIVHRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGNDEDPIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELITGNPPYYDLNPTAA----LYKIVNDDYPP--FPNTVSPQLREFLFSCFKRDPNQRASSRDLLKHKW 515
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280]) HSP 1 Score: 77.0258 bits (188), Expect = 2.081e-14 Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P S ++ FK +++CLN+DP R + + LL++KF Sbjct: 122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNPPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280]) HSP 1 Score: 76.6406 bits (187), Expect = 2.617e-14 Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P S ++ FK +++CLN+DP R + + LL++KF Sbjct: 126 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNPPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322]) HSP 1 Score: 75.0998 bits (183), Expect = 7.027e-14 Identity = 45/162 (27.78%), Postives = 87/162 (53.70%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYK-KYIFPVSIN----ERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL G++KLA + G++ Q + E ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + P ++N + FK +DSCLN+DP R + + LL++KF Sbjct: 120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFHIPKNTPPTLNGDFSKSFKEFVDSCLNKDPTFRPTAKELLKHKF 273
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322]) HSP 1 Score: 74.7146 bits (182), Expect = 1.174e-13 Identity = 45/162 (27.78%), Postives = 87/162 (53.70%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYK-KYIFPVSIN----ERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 ++ ++IL+GL LH ++ ++ +++LL G++KLA + G++ Q + E ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + P ++N + FK +DSCLN+DP R + + LL++KF Sbjct: 141 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFHIPKNTPPTLNGDFSKSFKEFVDSCLNKDPTFRPTAKELLKHKF 294
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk25a (serine/threonine-protein kinase 25 [Source:NCBI gene;Acc:103021644]) HSP 1 Score: 73.559 bits (179), Expect = 2.340e-13 Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL G++KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P S ++ FK +++CLN+DP R + + LL++KF Sbjct: 122 REILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNNPPTLEGSYSKAFKDFVEACLNKDPRFRPTAKELLKHKF 269
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399]) HSP 1 Score: 72.7886 bits (177), Expect = 2.463e-14 Identity = 47/142 (33.10%), Postives = 72/142 (50.70%), Query Frame = 1 Query: 1549 QILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKI-IPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962 +I+ GL LHD GI+Y +L + +ILLD G +K+A + K I G R DY+APEI+ + +N D WSFG++L E++ G+ F E E F I +P I + + ++ L +P R+ V Sbjct: 96 EIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQS-PFRGDDE---EELFESIRTSVPYYPRWITKDSRDILPLLLEREPMKRLGV 233
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 73.9442 bits (180), Expect = 3.773e-14 Identity = 50/159 (31.45%), Postives = 82/159 (51.57%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDEL--TMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N KN + +Y K FK +DSCLN+DP R + + LL++KF Sbjct: 128 REILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLEGNYSKA---------FKEFVDSCLNKDPQFRPTAKELLKHKF 277
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008193.1 (pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-1 gene:ENSPMAG00000007385.1 transcript:ENSPMAT00000008193.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 73.559 bits (179), Expect = 3.947e-14 Identity = 46/168 (27.38%), Postives = 80/168 (47.62%), Query Frame = 1 Query: 1510 RIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINK-------DYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEA------KNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974 R S + ++ W R I G++ LH H I++ +L ++L+ ++K++ K + R + + ++APE++ N+P + K D+WSFG++L E++TG+ + A N H P S E FK ++ C N P NR S R +L Sbjct: 95 RRISPELLVGWTRGIARGMSYLHLHKIIHRDLKSPNVLITHDDEVKISDFGTSK----EMREKSTRMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYRDVDSSAIIWGVGSNSLHL--------PIPASCPEGFKILLTQCWNSKPRNRPSFRQIL 250
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 70.8626 bits (172), Expect = 1.591e-13 Identity = 46/176 (26.14%), Postives = 80/176 (45.45%), Query Frame = 1 Query: 1486 FKAVDGKTRIA-SNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSIN--ERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 FK ++ + + S D+++ W Q+ L +HD I++ ++ +I L G ++L I +++ E+ + YL+PEI +NKP+N K+D+W+ G +L E+ T EA N + + PVS + + + L DP R V VLL Sbjct: 89 FKRINAQKGVLFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGIARVL--NSTTELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCT-----LRHAFEAGNMKNLVLKIIRGSFPPVSAHYSSELRSTLSGLLRRDPRARPPVAVLLSRPL 257
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: map2k7 (mitogen-activated protein kinase kinase 7 [Source:ZFIN;Acc:ZDB-GENE-090312-186]) HSP 1 Score: 70.4774 bits (171), Expect = 3.338e-13 Identity = 57/191 (29.84%), Postives = 98/191 (51.31%), Query Frame = 1 Query: 1441 VSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHD-HGIVYDELTMSHILLDSKGDIKLASINI-GKII--PGQKRNEINKDYLAPEILD-----NKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 V ++MELM ++ K + G I N + K I++ L+ L + HG+++ ++ S+ILLDS+G IKL I G+++ + R Y+APE +D + ++I+ADVWS GI L+E+ TG+ + KT+ + + + D + + F+ + CL +D R LLE+ F Sbjct: 148 VFIAMELMGTCAEKLKKRIQGP--IPEN-ILGKMTVAIVKALSYLKEKHGVIHRDVKPSNILLDSRGRIKLCDFGISGRLVDSKAKTRGAGCAAYMAPERIDPPDPTHPDYDIRADVWSLGISLVELATGQFPYQNCKTDFEVLTKVLQEDPPLLPSDMGFSLDFQAFVKDCLTKDHRKRPKYNKLLEHAF 335
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061]) HSP 1 Score: 73.9442 bits (180), Expect = 3.627e-14 Identity = 56/216 (25.93%), Postives = 104/216 (48.15%), Query Frame = 1 Query: 1393 SERFVRIFAIYKGEGLVSV--SMELMAI-SLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP---------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 S+ V+ + ++ E S+ +ME M SL+ +K + + S + K +L GL+ LH+ +++ ++ +ILL+ KG+IKL + G+ N + Y+APE + +P+++ DVWS G+ LLE+ G+ F F + +N + + P +S ++ F+ ID CL +D R S R +L++ + Sbjct: 270 SDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVS----GEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGR-FPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPW 480
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: PKH1 (Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898]) HSP 1 Score: 71.633 bits (174), Expect = 2.840e-13 Identity = 45/175 (25.71%), Postives = 85/175 (48.57%), Query Frame = 1 Query: 1522 NDEVIKWY-RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEIN-----------------KDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF*H 1992 N+ ++Y QI++ + LH+ GI++ ++ +ILLD +KL KI+P + N + +Y++PE+L++ + + D+W+FG IL +++ GK F A E KI +Y F + K ++ L DPN+R++++ + + F H Sbjct: 222 NETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKP-PFKAANEYLTFQKVMKI---QYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFH 392
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757]) HSP 1 Score: 70.0922 bits (170), Expect = 4.823e-13 Identity = 55/216 (25.46%), Postives = 102/216 (47.22%), Query Frame = 1 Query: 1393 SERFVRIFAIYKGE--GLVSVSMELMAI-SLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP---------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 SE VR + ++ + + ++ME M SL +K + + S + K +L GL+ LH+ +++ ++ +ILL+ G +KL + G+ N + Y+APE + +P+++ +DVWS G+ +LE+ GK F S++ A N + F + + P + + FK ID CL +D R S R ++ + + Sbjct: 277 SEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVS----GEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGK-FPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPW 487
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 69.707 bits (169), Expect = 5.438e-13 Identity = 45/145 (31.03%), Postives = 69/145 (47.59%), Query Frame = 1 Query: 1531 VIKWYR-QILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEIN-KDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRIS 1959 V K+Y ++ L LH I+Y +L +ILLD G IK+ K +P DY+APE++ KP+N D WSFGI++ E++ G + + T E KI + FP NE K ++ + D + R+ Sbjct: 186 VAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYE----KILNAELRFPPFFNEDVKDLLSRLITRDLSQRLG 326
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: GIN4 (Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915]) HSP 1 Score: 67.0106 bits (162), Expect = 7.537e-12 Identity = 50/177 (28.25%), Postives = 86/177 (48.59%), Query Frame = 1 Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEI---NKDYLAPEILDNKPW-NIKADVWSFGIILLEIITGKC-FNFSAKTEAKNESHFFKIDYKKYIFPVS--INERFKGVIDSCLNEDPNNRISVRVLLENKF*H*F*RFPIIFAYEGCR 2037 E I+++RQI+ G++ H GIV+ +L ++LLD K +IK+A + + K E + Y APEI+ P+ +DVWS G+IL ++TG+ F+ + + + K+ ++ P I+ + +I L DP RI R +L + P++ Y R Sbjct: 132 EAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFD---EEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDIL---------KHPLLQKYPSIR 296
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO49822 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG20]) HSP 1 Score: 82.8037 bits (203), Expect = 2.182e-17 Identity = 53/174 (30.46%), Postives = 91/174 (52.30%), Query Frame = 1 Query: 1486 FKAVDGKTRIA-SNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQ---KRNEINKDY-LAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHF-FKIDYKKY-IFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 +K ++G+ IA S D+V+ W+ QI GL +HD I++ ++ +I L G IK+ I +++ R I Y L+PEI++N+P+N K+D+WS G +L E++T EA N + KI Y P+ + + ++ L +P++R SV +L+ F Sbjct: 89 YKKINGQRGIAFSEDQVMDWFVQICLGLKHVHDRKILHRDIKSQNIFLTRHGIIKMGDFGIARVLHSTVELARTCIGTPYYLSPEIVENRPYNNKSDIWSLGCVLYEMLT-----LKHAFEAGNMKNLVLKIIRGSYPPIPLRYSADIRMLVAQLLKRNPHDRPSVNTVLKKNF 257
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO35437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH0]) HSP 1 Score: 78.9518 bits (193), Expect = 6.249e-16 Identity = 62/249 (24.90%), Postives = 119/249 (47.79%), Query Frame = 1 Query: 1255 LIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERF---VRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 L +EK + YI +V +K+ + S++ +LR+ + + R +R+F + + V + +E E +K + + K+ RQ+ + LA H +++ ++ ++LL+ KGDIK+A P +R + DYL PE+++ K + K D+WS G++ E + GK F A E NE+ + +I FP ++ + +I L +PNNR+ ++ +L + + Sbjct: 64 LAREKKSKYIVALKVL--------FKSQLQKSNVEHQLRREIEIQSHLRHNNILRLFGYFYDDTRVYLILEYAPRG--ELYKELTACEKF-DEKRAAKYIRQLADALAYCHSKKVIHRDIKPENLLLNYKGDIKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGKEHDEKVDLWSIGVLCYEFLVGKP-PFEA--EGHNET-YRRISRVDLRFPSHVSPGARDLISKLLQHNPNNRLPLKAVLNHPW 297
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO45846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL1]) HSP 1 Score: 72.7886 bits (177), Expect = 5.884e-14 Identity = 42/160 (26.25%), Postives = 81/160 (50.62%), Query Frame = 1 Query: 1519 SNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASIN----IGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 S ++V R +L+ L LH G+++ ++ ILL S G +KL+ + + +P +K ++APE++ KP+ + D+WS GI++LE++ G+ F+ + + ++ P+ I+ R + +D+ L DP R + LL + F Sbjct: 121 SEEQVACVCRAVLKALTFLHSQGVIHRDIKSDSILLTSNGTVKLSDFGFCAQVTEDMPRRKSLVGTPYWMAPEVISRKPYGTEVDIWSLGIMVLEMVDGEPPYFN-EPPLQAMRKLRDLEPPTSRNPIQISPRLQSFLDNALIRDPLYRATAFELLNHPF 279
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO35585 (Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7SL27]) HSP 1 Score: 73.1738 bits (178), Expect = 2.230e-13 Identity = 38/122 (31.15%), Postives = 68/122 (55.74%), Query Frame = 1 Query: 1540 WYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-IDYKKYIFPV 1890 + +++ L LH +G++Y +L + ++LLD+ G IKLA + K + PG+ DY+APEIL +P+ D W+ G+++ E++ G+ EA+NE F+ I + ++PV Sbjct: 487 YAAEVVLALQFLHQNGVIYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMMAGQ-----PPFEAENEEDLFESILHDDVLYPV 603
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4]) HSP 1 Score: 72.0182 bits (175), Expect = 2.753e-13 Identity = 43/163 (26.38%), Postives = 85/163 (52.15%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP--------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R++L+GL LH ++ ++ +++L+ GD+KLA + GQ + +NK ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ ++ P + ++ FK + CLN+DPN+R + + LL+++F Sbjct: 113 REVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVA----GQLTDTLNKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPN--------SDLHPMRV---LFLIPKNNPPELTGNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRF 260
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729]) HSP 1 Score: 75.8702 bits (185), Expect = 4.395e-14 Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P ++ FK +++CLN+DP R + + LL++KF Sbjct: 122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGPYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729]) HSP 1 Score: 75.8702 bits (185), Expect = 4.616e-14 Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1 Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 R+IL+GL LH ++ ++ +++LL +GD+KLA + G++ Q KRN ++APE++ ++ KAD+WS GI +E+ G+ N ++ H ++ + K P ++ FK +++CLN+DP R + + LL++KF Sbjct: 122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGPYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985]) HSP 1 Score: 76.6406 bits (187), Expect = 8.068e-14 Identity = 50/161 (31.06%), Postives = 83/161 (51.55%), Query Frame = 1 Query: 1531 VIKWYRQILEGLACLHDHGIVYDELTMSHILLDS-KGDIKLASINIGK----IIPGQKRNEINKDYLAPEILDNKP--WNIKADVWSFGIILLEIITGKC--FNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 +I + +Q+LEGL LHD+ IV+ ++ ++L+++ G +K++ K I P + Y+APEI+D P + AD+WS G ++E+ TGK + A + FKI K P +++ KG I SC +P+NR + LL + F Sbjct: 677 IIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFAGTLQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPK---VPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTF 834
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985]) HSP 1 Score: 76.2554 bits (186), Expect = 8.389e-14 Identity = 50/161 (31.06%), Postives = 83/161 (51.55%), Query Frame = 1 Query: 1531 VIKWYRQILEGLACLHDHGIVYDELTMSHILLDS-KGDIKLASINIGK----IIPGQKRNEINKDYLAPEILDNKP--WNIKADVWSFGIILLEIITGKC--FNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 +I + +Q+LEGL LHD+ IV+ ++ ++L+++ G +K++ K I P + Y+APEI+D P + AD+WS G ++E+ TGK + A + FKI K P +++ KG I SC +P+NR + LL + F Sbjct: 733 IIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFAGTLQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPK---VPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTF 890
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: map2k7 (mitogen-activated protein kinase kinase 7 [Source:NCBI gene;Acc:101164950]) HSP 1 Score: 73.1738 bits (178), Expect = 3.267e-13 Identity = 57/192 (29.69%), Postives = 100/192 (52.08%), Query Frame = 1 Query: 1441 VSVSMELMAISLKEHFKAVDGKTRIASNDEVI-KWYRQILEGLACLHD-HGIVYDELTMSHILLDSKGDIKLASINI-GKII--PGQKRNEINKDYLAPEILD----NKP-WNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 V ++MELM ++ K + G ++++ K I++ L L + HG+++ ++ S+ILLD+KG IKL I G+++ + R+ Y+APE +D KP ++I+ADVWS GI L+E+ TG+ + KT+ + + + D + + F+ + CL +D R LLE+ F Sbjct: 209 VFIAMELMGTCAEKLKKRIQGPI----PEQILGKMTVAIVKALLYLKEKHGVIHRDVKPSNILLDAKGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEDPPLLPLGMGFSLDFQSFVKDCLTKDHRKRPKYHQLLEHSF 396
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003862.1 (SMESG000003862.1) HSP 1 Score: 948.732 bits (2451), Expect = 0.000e+0 Identity = 496/646 (76.78%), Postives = 551/646 (85.29%), Query Frame = 1 Query: 91 NVNGQEPIPVCSQNRPYRLFDSKCANFFEICTKQDDYECDQLQASCKQCPPSKITVKFLHDILRILNYXXXXXXXXXXXXXXXXXXXXXXENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEM-----EERP---------FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986 NVNGQEPI VCS+NRP+RL DSKCAN+ IC+KQDD +C+QLQ +CKQCPPS++TV L +ILRI+ Y+L+N +I ILI N+V F LL+ ENRFK+ITKFC L KK+ N Y ++ SRK + +N IGDFGTKLK RLPTENKVIELHVYGN+NVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGK ISDLNQILCKL + + ++VKP YS L + +TL A + DN +IV + +KPV+I F SIL++++ F ELS E VS+I+ ++QKFKSE+ VL++ +M S++FLFQYNID+ESQIKYCRF EM E +P FSI +FKKQ L KATD N+EV +M+Y+LSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVI SCLNEDPNNRISVRVLLENKF Sbjct: 15 NVNGQEPISVCSRNRPFRLSDSKCANYTGICSKQDDDQCNQLQNACKQCPPSEMTVIMLQEILRIVKYRLVNFLIAILIVNVVAFFLLVFENRFKIITKFCSLLCKKKQVNVYHLLQSRKGKTYYANCIGDFGTKLKLRLPTENKVIELHVYGNENVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKKISDLNQILCKLLDQSDLVIYVKPSDAANYSDLNNPDLTLVKAGVKDNDQIVAITKKPVKIMFSSILSNDENFNSELSNVERVSSILNIVEQKFKSED-VLIIGERDMISEQFLFQYNIDDESQIKYCRFNEMDAQDQEVKPLKESVGRLRFSIIGIFKKQELSQIYKATDNFNNKEVALMQYRLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIHSCLNEDPNNRISVRVLLENKF 659
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1) HSP 1 Score: 928.702 bits (2399), Expect = 0.000e+0 Identity = 482/656 (73.48%), Postives = 529/656 (80.64%), Query Frame = 1 Query: 22 MGYIVEFKAXXXXXXXXXXXXXXNVNGQEPIPVCSQNRPYRLFDSKCANFFEICTKQDDYECDQLQASCKQCPPSKITVKF--LHDILRILNYXXXXXXXXXXXXXXXXXXXXXXENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974 MGYI+EFK EPI VCSQNRPY LFDSKCANFF+ICTKQDDYECDQLQASCKQCPPSKITVK+ ++ +++IL + ++ ++ I+ ENRFKLI KKFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD MT EAAKLCD RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q YCRFYE EER S ++F KQ KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL N +ERFV+I AIYKG V+VSMELM++S+KE F +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI I G K ++ N +LAPEI K WNIKADVWSFG+ILLEIITGKCFNFSAK EA N+S+FFKIDY KYIFP SINERFKGVID CL EDPN RISV LL Sbjct: 1 MGYILEFK--------------------EPISVCSQNRPYTLFDSKCANFFDICTKQDDYECDQLQASCKQCPPSKITVKYQLMNIMIQILTFNIVIFVLLII------------ENRFKLI----------KKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIITGKCFNFSAKKEALNDSNFFKIDYTKYIFPRSINERFKGVIDRCLVEDPNYRISVHELL 614
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1) HSP 1 Score: 837.41 bits (2162), Expect = 0.000e+0 Identity = 435/598 (72.74%), Postives = 480/598 (80.27%), Query Frame = 1 Query: 22 MGYIVEFKAXXXXXXXXXXXXXXNVNGQEPIPVCSQNRPYRLFDSKCANFFEICTKQDDYECDQLQASCKQCPPSKITVKF--LHDILRILNYXXXXXXXXXXXXXXXXXXXXXXENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIIT 1800 MGYI+EFK EPI VCSQNRPY LFDSKCANFF+ICTKQDDYECDQLQASCKQCPPSKITVK+ ++ +++IL + ++ ++ I+ ENRFKLI KKFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD MT EAAKLCD RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q YCRFYE EER S ++F KQ KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL N +ERFV+I AIYKG V+VSMELM++S+KE F +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI I G K ++ N +LAPEI K WNIKADVWSFG+ILLEIIT Sbjct: 1 MGYILEFK--------------------EPISVCSQNRPYTLFDSKCANFFDICTKQDDYECDQLQASCKQCPPSKITVKYQLMNIMIQILTFNIVIFVLLII------------ENRFKLI----------KKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIIT 556
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1) HSP 1 Score: 823.543 bits (2126), Expect = 0.000e+0 Identity = 415/526 (78.90%), Postives = 450/526 (85.55%), Query Frame = 1 Query: 406 TKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974 + +KFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD MT EAAKLCD RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q YCRFYE EER S ++F KQ KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL N +ERFV+I AIYKG V+VSMELM++S+KE F +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI I G K ++ N +LAPEI K WNIKADVWSFG+ILLEIITGKCFNFSAK EA N+S+FFKIDY KYIFP SINERFKGVID CL EDPN RISV LL Sbjct: 67 SNEKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIITGKCFNFSAKKEALNDSNFFKIDYTKYIFPRSINERFKGVIDRCLVEDPNYRISVHELL 592
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1) HSP 1 Score: 822.772 bits (2124), Expect = 0.000e+0 Identity = 415/526 (78.90%), Postives = 450/526 (85.55%), Query Frame = 1 Query: 406 TKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974 + +KFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD MT EAAKLCD RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q YCRFYE EER S ++F KQ KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL N +ERFV+I AIYKG V+VSMELM++S+KE F +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI I G K ++ N +LAPEI K WNIKADVWSFG+ILLEIITGKCFNFSAK EA N+S+FFKIDY KYIFP SINERFKGVID CL EDPN RISV LL Sbjct: 51 SNEKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIITGKCFNFSAKKEALNDSNFFKIDYTKYIFPRSINERFKGVIDRCLVEDPNYRISVHELL 576 The following BLAST results are available for this feature:
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035587 ID=SMED30035587|Name=Serine/threonine protein kinase, putative|organism=Schmidtea mediterranea sexual|type=transcript|length=2322bpback to top protein sequence of SMED30035587-orf-1 >SMED30035587-orf-1 ID=SMED30035587-orf-1|Name=SMED30035587-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=656bp MGYIVEFKAIEIILGILHLFILLNVNGQEPIPVCSQNRPYRLFDSKCANFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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