Serine/threonine protein kinase, putative

Overview
NameSerine/threonine protein kinase, putative
Smed IDSMED30035587
Length (bp)2322
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serine/threonine protein kinase, putative (SMED30035587) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine/threonine protein kinase, putative (SMED30035587) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine/threonine protein kinase, putative (SMED30035587) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serine/threonine protein kinase, putative (SMED30035587) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30035587

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 50

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30035587h1SMcG0001939 Contig4602GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0016992 Contig4602GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0001939 Contig985uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0001939 Contig985newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0015679 Contig985uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0015679 Contig985newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0001939 Contig4602GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0016992 Contig4602GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0001939 Contig985uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0001939 Contig985newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0015679 Contig985uc_Smed_v2PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035587h1SMcG0015679 Contig985newmark_estsPMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig4418newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig4418uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig14391uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig14391newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0002174 Contig4418newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0002174 Contig4418uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035587h1SMcG0001938 dd_Smed_v4_16170_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30035587h1SMcG0001938 dd_Smed_v4_16170_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig6733newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig6733uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig4418newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig4418uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig14391uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig14391newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0002174 Contig4418newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0002174 Contig4418uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
gutSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035587h1SMcG0001938 dd_Smed_v4_16170_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parapharyngeal regionSMED30035587h1SMcG0001938 dd_Smed_v4_16170_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig6733newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035587h1SMcG0001939 Contig6733uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
parenchymal cellSMED30035587h1SMcG0001939 dd_Smed_v6_3667_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035587h1SMcG0001938 dd_Smed_v6_3667_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035587h1SMcG0001939 dd_Smed_v6_3667_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035587h1SMcG0001938 dd_Smed_v6_3667_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035587h1SMcG0001939 dd_Smed_v4_3667_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174])

HSP 1 Score: 77.411 bits (189), Expect = 1.367e-14
Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  + +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:   43 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 196          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174])

HSP 1 Score: 77.0258 bits (188), Expect = 2.689e-14
Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  + +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174])

HSP 1 Score: 77.411 bits (189), Expect = 2.931e-14
Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  + +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK25 (serine/threonine kinase 25 [Source:HGNC Symbol;Acc:HGNC:11404])

HSP 1 Score: 73.1738 bits (178), Expect = 3.108e-14
Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P      ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:   28 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 175          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Match: STK26 (serine/threonine kinase 26 [Source:HGNC Symbol;Acc:HGNC:18174])

HSP 1 Score: 77.411 bits (189), Expect = 3.256e-14
Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  + +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  142 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 295          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3])

HSP 1 Score: 73.1738 bits (178), Expect = 6.468e-14
Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++ L+ L  LH H IV+ ++   ++LL   G++KL  +    +I PG KR+ +     +++PEIL+ K +N K D+WS GI+ LE+I G             E  + +    K I+ ++ N +            F   +D CL  DP+ R     LL + F
Sbjct:  101 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 249          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3])

HSP 1 Score: 72.7886 bits (177), Expect = 3.077e-13
Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++ L+ L  LH H IV+ ++   ++LL   G++KL  +    +I PG KR+ +     +++PEIL+ K +N K D+WS GI+ LE+I G             E  + +    K I+ ++ N +            F   +D CL  DP+ R     LL + F
Sbjct:  258 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 406          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3])

HSP 1 Score: 72.7886 bits (177), Expect = 4.797e-13
Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++ L+ L  LH H IV+ ++   ++LL   G++KL  +    +I PG KR+ +     +++PEIL+ K +N K D+WS GI+ LE+I G             E  + +    K I+ ++ N +            F   +D CL  DP+ R     LL + F
Sbjct:  430 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 578          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3])

HSP 1 Score: 72.7886 bits (177), Expect = 4.862e-13
Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++ L+ L  LH H IV+ ++   ++LL   G++KL  +    +I PG KR+ +     +++PEIL+ K +N K D+WS GI+ LE+I G             E  + +    K I+ ++ N +            F   +D CL  DP+ R     LL + F
Sbjct:  433 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 581          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Match: max-2 (Serine/threonine-protein kinase max-2 [Source:UniProtKB/Swiss-Prot;Acc:G5EGQ3])

HSP 1 Score: 72.7886 bits (177), Expect = 5.393e-13
Identity = 47/162 (29.01%), Postives = 78/162 (48.15%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINER------------FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++ L+ L  LH H IV+ ++   ++LL   G++KL  +    +I PG KR+ +     +++PEIL+ K +N K D+WS GI+ LE+I G             E  + +    K I+ ++ N +            F   +D CL  DP+ R     LL + F
Sbjct:  481 QECLKALHFLHRHSIVHRDIKSDNVLLGMNGEVKLTDMGFCAQIQPGSKRDTVVGTPYWMSPEILNKKQYNYKVDIWSLGIMALEMIDG-------------EPPYLRETPLKAIYLIAQNGKPEIKQRDRLSSEFNNFLDKCLVVDPDQRADTTELLAHPF 629          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: inaC (gene:FBgn0004784 transcript:FBtr0087047)

HSP 1 Score: 78.5666 bits (192), Expect = 1.152e-14
Identity = 45/135 (33.33%), Postives = 73/135 (54.07%), Query Frame = 1
Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNE----INKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-IDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962
            LH+  I+Y +L + +ILLD +G +KL    + K    +++         +Y+APEI+   P++I AD WSFG++L E + G+     A  E  +E+  F+ I  KK +FP   +     +I S L + PNNR+  
Sbjct:  486 LHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ-----APFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGA 615          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399)

HSP 1 Score: 75.8702 bits (185), Expect = 7.000e-14
Identity = 46/163 (28.22%), Postives = 83/163 (50.92%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP--------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R++L+GL  LH    ++ ++  +++LL  +GD+KLA   +     GQ  N  +K         ++APE++    ++ KAD+WS GI  +E+  G+  N        +E H  ++    ++ P         S  + FK  +++CLN+DP NR + + LL+  F
Sbjct:  115 REVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVA----GQLTNTTSKRNTFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPN--------SELHPMRV---LFLIPKNNPPQLTGSYTKSFKDFVEACLNKDPENRPTAKELLKYPF 262          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0303432)

HSP 1 Score: 74.7146 bits (182), Expect = 1.325e-13
Identity = 43/139 (30.94%), Postives = 77/139 (55.40%), Query Frame = 1
Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC-FNFSAKTEAKN---ESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISV 1962
            LH+ GI+Y +L + ++LLD +G IKL    + K  I PG   +      +Y+APEIL  + +    D W+ G++L E++ G+  F+ +  +E  +   E + F++  +K I  P S++ R   V+   LN++P +R+  
Sbjct:  297 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC 435          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0329888)

HSP 1 Score: 74.7146 bits (182), Expect = 1.377e-13
Identity = 43/139 (30.94%), Postives = 77/139 (55.40%), Query Frame = 1
Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC-FNFSAKTEAKN---ESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISV 1962
            LH+ GI+Y +L + ++LLD +G IKL    + K  I PG   +      +Y+APEIL  + +    D W+ G++L E++ G+  F+ +  +E  +   E + F++  +K I  P S++ R   V+   LN++P +R+  
Sbjct:  292 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC 430          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Match: aPKC (gene:FBgn0261854 transcript:FBtr0303429)

HSP 1 Score: 74.7146 bits (182), Expect = 1.403e-13
Identity = 43/139 (30.94%), Postives = 77/139 (55.40%), Query Frame = 1
Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC-FNFSAKTEAKN---ESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISV 1962
            LH+ GI+Y +L + ++LLD +G IKL    + K  I PG   +      +Y+APEIL  + +    D W+ G++L E++ G+  F+ +  +E  +   E + F++  +K I  P S++ R   V+   LN++P +R+  
Sbjct:  297 LHEKGIIYRDLKLDNVLLDHEGHIKLTDYGMCKEGIRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLLYEMLAGRSPFDLAGASENPDQNTEDYLFQVILEKTIRIPRSLSVRAASVLKGFLNKNPADRLGC 435          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537])

HSP 1 Score: 76.6406 bits (187), Expect = 1.578e-14
Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P    S ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:   33 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 180          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk25b (serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-GENE-040426-2537])

HSP 1 Score: 77.411 bits (189), Expect = 1.680e-14
Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P    S ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk26 (serine/threonine protein kinase 26 [Source:ZFIN;Acc:ZDB-GENE-080516-5])

HSP 1 Score: 74.3294 bits (181), Expect = 1.378e-13
Identity = 46/163 (28.22%), Postives = 81/163 (49.69%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL   G++KLA   + G++   Q + E       ++APE++    ++ KAD+WS GI  +E+  G+  N             KN       D+ K          FK  +DSCLN+DP  R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFHIPKNTPPTLNGDFSKI---------FKEFVDSCLNKDPAFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: stk24a (serine/threonine kinase 24a (STE20 homolog, yeast) [Source:ZFIN;Acc:ZDB-GENE-070424-52])

HSP 1 Score: 74.3294 bits (181), Expect = 1.644e-13
Identity = 49/161 (30.43%), Postives = 84/161 (52.17%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSI----NERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+             AK E     +   K +F      P ++    N+  K  +D+CLN+DPN R + + LL++K 
Sbjct:  119 REILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSEYDSKADIWSLGITAIEL-------------AKGEPPHSDLHPMKVLFLIPKENPPTLEGNYNKALKEFVDACLNKDPNFRPTAKELLKHKL 266          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Match: map2k7 (mitogen-activated protein kinase kinase 7 [Source:ZFIN;Acc:ZDB-GENE-090312-186])

HSP 1 Score: 74.3294 bits (181), Expect = 1.738e-13
Identity = 58/191 (30.37%), Postives = 98/191 (51.31%), Query Frame = 1
Query: 1441 VSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHD-HGIVYDELTMSHILLDSKGDIKLASINI-GKII--PGQKRNEINKDYLAPEILD----NKP-WNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            V ++MELM    ++  K + G    A    + K    I+  L  L + HG+++ ++  S+ILLD+KG IKL    I G+++    + R+     Y+APE +D    +KP ++I+ADVWS GI L+E+ TG+    + KT+ +  +   + D       +  +  F+  +  CL +D   R     LLE+ F
Sbjct:  200 VFIAMELMGTCAEKLKKRIQGPIPEAI---LGKMTVAIVNALLYLKEKHGVIHRDVKPSNILLDAKGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPSKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEDPPVLPLSMGFSPDFQSFVKDCLTKDHRKRPKYHKLLEHSF 387          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 78.5666 bits (192), Expect = 7.644e-15
Identity = 48/161 (29.81%), Postives = 86/161 (53.42%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSINER----FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+             AK E  +  +   + +F      P S+  +    FK  +++CLN+DP +R + R LL+++F
Sbjct:  109 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-------------AKGEPPYSDLHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELLKHRF 256          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 78.5666 bits (192), Expect = 8.399e-15
Identity = 48/161 (29.81%), Postives = 86/161 (53.42%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSINER----FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+             AK E  +  +   + +F      P S+  +    FK  +++CLN+DP +R + R LL+++F
Sbjct:  109 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-------------AKGEPPYSDLHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELLKHRF 256          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: stk25 (serine/threonine kinase 25 [Source:NCBI gene;Acc:548355])

HSP 1 Score: 78.5666 bits (192), Expect = 9.664e-15
Identity = 48/161 (29.81%), Postives = 86/161 (53.42%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIF------PVSINER----FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+             AK E  +  +   + +F      P S+  +    FK  +++CLN+DP +R + R LL+++F
Sbjct:  109 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIEL-------------AKGEPPYSDLHPMRVLFLIPKNNPPSLQGQYSKPFKDFVEACLNKDPRSRPTARELLKHRF 256          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: cpvl (carboxypeptidase, vitellogenic-like [Source:Xenbase;Acc:XB-GENE-1014879])

HSP 1 Score: 78.5666 bits (192), Expect = 1.106e-14
Identity = 51/171 (29.82%), Postives = 87/171 (50.88%), Query Frame = 1
Query: 1510 RIASNDE--VIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+   DE  +    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N             KN       D+ K          FK  +D+CLN+DP+ R + R LL++K+
Sbjct:  112 RVGPFDEFQIATMLKEILKGLDYLHSENKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPSLTGDFSK---------PFKEFVDACLNKDPSFRPTARELLKHKY 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Match: cpvl (carboxypeptidase, vitellogenic-like [Source:Xenbase;Acc:XB-GENE-1014879])

HSP 1 Score: 78.1814 bits (191), Expect = 1.110e-14
Identity = 51/171 (29.82%), Postives = 87/171 (50.88%), Query Frame = 1
Query: 1510 RIASNDE--VIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+   DE  +    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N             KN       D+ K          FK  +D+CLN+DP+ R + R LL++K+
Sbjct:  100 RVGPFDEFQIATMLKEILKGLDYLHSENKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKNNPPSLTGDFSK---------PFKEFVDACLNKDPSFRPTARELLKHKY 261          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665])

HSP 1 Score: 77.411 bits (189), Expect = 1.582e-14
Identity = 49/162 (30.25%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  I +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Stk26 (serine/threonine kinase 26 [Source:MGI Symbol;Acc:MGI:1917665])

HSP 1 Score: 77.411 bits (189), Expect = 1.749e-14
Identity = 49/162 (30.25%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  I +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Stk25 (serine/threonine kinase 25 (yeast) [Source:MGI Symbol;Acc:MGI:1891699])

HSP 1 Score: 73.1738 bits (178), Expect = 4.445e-13
Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P      ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  122 REILKGLDYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNNPPTLEGHHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Prkci (protein kinase C, iota [Source:MGI Symbol;Acc:MGI:99260])

HSP 1 Score: 73.9442 bits (180), Expect = 4.458e-13
Identity = 42/140 (30.00%), Postives = 74/140 (52.86%), Query Frame = 1
Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKC----FNFSAKTEAKNESHFFKIDYKKYI-FPVSINERFKGVIDSCLNEDPNNRISVR 1965
            LH+ GI+Y +L + ++LLDS+G IKL    + K  + PG   +      +Y+APEIL  + +    D W+ G+++ E++ G+        S   +   E + F++  +K I  P S++ +   V+ S LN+DP  R+   
Sbjct:  368 LHERGIIYRDLKLDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFEMMAGRSPFDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSLSVKAASVLKSFLNKDPKERLGCH 507          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Match: Prkcd (protein kinase C, delta [Source:MGI Symbol;Acc:MGI:97598])

HSP 1 Score: 73.1738 bits (178), Expect = 6.871e-13
Identity = 45/145 (31.03%), Postives = 74/145 (51.03%), Query Frame = 1
Query: 1549 QILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKI-IPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFF---KIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962
            +I+ GL  LH  GI+Y +L + +++LD  G IK+A   + K  I G+ R        DY+APEIL    ++   D WSFG++L E++ G+     +     +E   F   ++D   Y  P  I +  K +++     DP+ R+ V
Sbjct:  339 EIICGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQ-----SPFHGDDEDELFESIRVDTPHY--PRWITKESKDIMEKLFERDPDKRLGV 476          
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q9S7U9|M2K2_ARATH (Mitogen-activated protein kinase kinase 2 OS=Arabidopsis thaliana OX=3702 GN=MKK2 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 9.546e-14
Identity = 51/196 (26.02%), Postives = 101/196 (51.53%), Query Frame = 1
Query: 1435 GLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLH-DHGIVYDELTMSHILLDSKGDIKLASINIGKII---PGQKRNEINK-DYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-----IDYKKYIFPVS-INERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            G +S+ +E M   SL +  K+V    +   +  +   +RQ+L+GL  LH D  I++ +L  S++L++ +G++K+    +  ++    G     +   +Y++PE +    +  K+D+WS G+++LE  TGK F ++   + +  +  F+     +D      P    +      I +CL +DPN+R S + L+E+ F
Sbjct:  139 GAISLILEYMDGGSLADFLKSV----KAIPDSYLSAIFRQVLQGLIYLHHDRHIIHRDLKPSNLLINHRGEVKITDFGVSTVMTNTAGLANTFVGTYNYMSPERIVGNKYGNKSDIWSLGLVVLECATGK-FPYAPPNQEETWTSVFELMEAIVDQPPPALPSGNFSPELSSFISTCLQKDPNSRSSAKELMEHPF 329          
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q99JT2|STK26_MOUSE (Serine/threonine-protein kinase 26 OS=Mus musculus OX=10090 GN=Stk26 PE=1 SV=1)

HSP 1 Score: 77.411 bits (189), Expect = 1.106e-13
Identity = 49/162 (30.25%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  I +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLIGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|P13677|KPC2_DROME (Protein kinase C, eye isozyme OS=Drosophila melanogaster OX=7227 GN=inaC PE=1 SV=1)

HSP 1 Score: 78.5666 bits (192), Expect = 1.155e-13
Identity = 45/135 (33.33%), Postives = 73/135 (54.07%), Query Frame = 1
Query: 1573 LHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNE----INKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-IDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962
            LH+  I+Y +L + +ILLD +G +KL    + K    +++         +Y+APEI+   P++I AD WSFG++L E + G+     A  E  +E+  F+ I  KK +FP   +     +I S L + PNNR+  
Sbjct:  486 LHERDIIYRDLKLDNILLDGEGHVKLVDFGLSKEGVTERQTTRTFCGTPNYMAPEIVSYDPYSIAADWWSFGVLLFEFMAGQ-----APFEGDDETTVFRNIKDKKAVFPKHFSVEAMDIITSFLTKKPNNRLGA 615          
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q9P289|STK26_HUMAN (Serine/threonine-protein kinase 26 OS=Homo sapiens OX=9606 GN=STK26 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 1.408e-13
Identity = 48/162 (29.63%), Postives = 89/162 (54.94%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPVSINE---RFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P  + +    FK  ID+CLN+DP+ R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFLIPKNNPPTLVGDFTKSFKEFIDACLNKDPSFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Match: sp|Q55GC2|DST2_DICDI (Serine/threonine-protein kinase dst2 OS=Dictyostelium discoideum OX=44689 GN=dst2 PE=3 SV=1)

HSP 1 Score: 78.1814 bits (191), Expect = 1.999e-13
Identity = 54/162 (33.33%), Postives = 86/162 (53.09%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNE-INKDY-LAPEILDNK----PWNIKADVWSFGIILLEIITGKCFNFSAKTEAK-NESHFFKIDYK-KYIFPVSINER------FKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+ L+GL  LH   +++ +L  ++ILL   GD+KLA   + G +    KRN  I   Y +APE+++N+    P++ KAD+WS GI L+E+         A+ E   +E H  K+ ++  Y  P  +  +      F   I SCL +DPN R +   LL++ F
Sbjct:  123 RETLKGLEYLHHTNVIHRDLKGANILLTESGDVKLADFGVSGLLDKSSKRNTFIGTPYWMAPEVIENRSNPVPYDTKADIWSLGITLIEL---------AEAEPPLSEIHPMKVLFQIPYRDPPKLKNQENYSKDFINFIQSCLQKDPNQRKTATELLKHPF 275          
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: A0A371IGI6 (Mitogen-activated protein kinase kinase kinase NPK1 (Fragment) OS=Mucuna pruriens OX=157652 GN=NPK1 PE=3 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.621e-15
Identity = 67/225 (29.78%), Postives = 115/225 (51.11%), Query Frame = 1
Query: 1339 INNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWY-RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIP--GQKRNEINKD--YLAPEILDNKPWNIKADVWSFGIILLEIITGK---CFNFSAK-TEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +   +L KE++ L  +N+S   V+   I + +G +++ ME MA         V  K   + +++V++ Y R+IL G+  LH HGIV+ +L  +++LL S G+IKLA     K +         I     ++APE+L N+  +  AD+WS G  ++E+ TGK       S   T   N +H  +I +    FP   ++     +  C++ +P NR +V+ LL + F
Sbjct:   50 VGRDALDKEIKILRTLNSSPYIVQCLGIQEDQGKLNIFMEYMA---GGSLADVAHKFGGSLDEKVVRIYTREILHGINHLHQHGIVHCDLKCNNVLLGSSGNIKLADFGCAKRVKDLANSWQSIGGTPLWMAPEVLRNESLDFAADIWSLGCTVIEMATGKPPWANQLSNPITAVLNIAHGDRIPH----FPSHFSKDGLDFLSRCMDREPKNRSTVKELLCHPF 267          
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: C4M8G8 (Serine/threonine protein kinase, putative OS=Entamoeba histolytica OX=5759 GN=EHI_063010 PE=4 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 2.522e-15
Identity = 67/235 (28.51%), Postives = 116/235 (49.36%), Query Frame = 1
Query: 1339 INNSSLIKE-------LRKLTVMNASERFVRIFAIYKGEGLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKI---DYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +N  S++KE       L+KL      +  VR  A  +  G + + ME M + SL    K  +      S     K+  Q+L+GLA +HD GIV+ ++  ++IL+   G +K+A   +   + G ++ E   D        ++APE++  +   +KAD+W+ G  ++E+ITG    +     A      +KI   DY    FP +++ + + ++ SC   DPN R S R LL++K+
Sbjct:   35 VNKKSVMKEVMEEIRLLKKL----KHKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLS----AKYIHQVLDGLAFIHDQGIVHRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGSDEDPIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELITGNPPYYDLNPTAA----LYKIVNDDYPP--FPNTVSPQLREILFSCFKRDPNQRASSRDLLKHKW 255          
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: A0A5K1UP00 (Serine threonine protein kinase putative OS=Entamoeba histolytica OX=5759 GN=CL6EHI_063010 PE=4 SV=1)

HSP 1 Score: 92.4337 bits (228), Expect = 2.522e-15
Identity = 67/235 (28.51%), Postives = 116/235 (49.36%), Query Frame = 1
Query: 1339 INNSSLIKE-------LRKLTVMNASERFVRIFAIYKGEGLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKI---DYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +N  S++KE       L+KL      +  VR  A  +  G + + ME M + SL    K  +      S     K+  Q+L+GLA +HD GIV+ ++  ++IL+   G +K+A   +   + G ++ E   D        ++APE++  +   +KAD+W+ G  ++E+ITG    +     A      +KI   DY    FP +++ + + ++ SC   DPN R S R LL++K+
Sbjct:   35 VNKKSVMKEVMEEIRLLKKL----KHKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLS----AKYIHQVLDGLAFIHDQGIVHRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGSDEDPIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELITGNPPYYDLNPTAA----LYKIVNDDYPP--FPNTVSPQLREILFSCFKRDPNQRASSRDLLKHKW 255          
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: A0A4P9XQV2 (Kinase-like domain-containing protein (Fragment) OS=Thamnocephalis sphaerospora OX=78915 GN=THASP1DRAFT_2332 PE=3 SV=1)

HSP 1 Score: 86.6557 bits (213), Expect = 4.736e-15
Identity = 59/227 (25.99%), Postives = 114/227 (50.22%), Query Frame = 1
Query: 1327 WKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAV--DGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKII----PGQKRNEIN-KDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            WK  +N  ++   LR   V+       R++  ++    V + MEL   +  E F  +  +G+ R  +        RQ++ GL  LH HG+++ +L +S++LL +   +KL    +  ++    P ++R      +Y+APE+L ++P+  ++D+WS G IL+ ++TG+   F  ++ A+       I    Y  P S++   + +    L +DP+ RIS++  L + F
Sbjct:   47 WKRVVNEVTIHLRLRHPAVL-------RLYDCFEDADHVYLVMEL--CTGGELFGQLHRNGRRRRLTEARTRDIMRQLISGLMYLHAHGVLHRDLKLSNVLLTADHRVKLGDFGLATLLRANRPDERRTLCGTPNYIAPEVLAHEPYGFESDIWSLGCILVALLTGRG-PFEGQSTAET---LDNIRNCTYSLPGSMSVASRDLARRFLQKDPHRRISLQKALLHPF 260          
BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Match: K2HFC6 (Serine/threonine protein kinase, putative OS=Entamoeba nuttalli (strain P19) OX=1076696 GN=ENU1_052280 PE=4 SV=1)

HSP 1 Score: 89.7373 bits (221), Expect = 1.729e-14
Identity = 66/235 (28.09%), Postives = 114/235 (48.51%), Query Frame = 1
Query: 1339 INNSSLIKE-------LRKLTVMNASERFVRIFAIYKGEGLVSVSMELM-AISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKI---DYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +N  S++KE       L+KL      +  VR  A  +  G + + ME M + SL    K  +      S     K+  Q+L+GL  +HD GIV+ ++  ++IL+   G +K+A   +   + G ++ E   D        ++APE++  +   +KAD+W+ G  ++E+ITG    +     A      +KI   DY    FP +++ + +  + SC   DPN R S R LL++K+
Sbjct:  295 VNKKSVMKEVMEEIRLLKKL----KHKHIVRYIASTESHGFLYIIMEYMESGSLLNIVKKFNHLNESLS----AKYIHQVLDGLTFIHDQGIVHRDIKAANILVAKDGSVKIADFGVSVQMNGNEKQETGNDEDPIGTPNWMAPEVIQMQGTTVKADIWALGCTVIELITGNPPYYDLNPTAA----LYKIVNDDYPP--FPNTVSPQLREFLFSCFKRDPNQRASSRDLLKHKW 515          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280])

HSP 1 Score: 77.0258 bits (188), Expect = 2.081e-14
Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P    S ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNPPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk25b (serine/threonine-protein kinase 25-like [Source:NCBI gene;Acc:103039280])

HSP 1 Score: 76.6406 bits (187), Expect = 2.617e-14
Identity = 48/156 (30.77%), Postives = 87/156 (55.77%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P    S ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  126 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNPPPTLEGSYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322])

HSP 1 Score: 75.0998 bits (183), Expect = 7.027e-14
Identity = 45/162 (27.78%), Postives = 87/162 (53.70%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYK-KYIFPVSIN----ERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL   G++KLA   + G++   Q + E       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +      P ++N    + FK  +DSCLN+DP  R + + LL++KF
Sbjct:  120 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFHIPKNTPPTLNGDFSKSFKEFVDSCLNKDPTFRPTAKELLKHKF 273          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk26 (serine/threonine kinase 26 [Source:NCBI gene;Acc:103024322])

HSP 1 Score: 74.7146 bits (182), Expect = 1.174e-13
Identity = 45/162 (27.78%), Postives = 87/162 (53.70%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYK-KYIFPVSIN----ERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            ++    ++IL+GL  LH    ++ ++  +++LL   G++KLA   + G++   Q + E       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +      P ++N    + FK  +DSCLN+DP  R + + LL++KF
Sbjct:  141 QIATMLKEILKGLDYLHSEKKIHRDIKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVIQQSAYDSKADIWSLGITAIELAKGEPPN--------SDMHPMRVLFHIPKNTPPTLNGDFSKSFKEFVDSCLNKDPTFRPTAKELLKHKF 294          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Match: stk25a (serine/threonine-protein kinase 25 [Source:NCBI gene;Acc:103021644])

HSP 1 Score: 73.559 bits (179), Expect = 2.340e-13
Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL   G++KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P    S ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  122 REILKGLDYLHSERKIHRDIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNNPPTLEGSYSKAFKDFVEACLNKDPRFRPTAKELLKHKF 269          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: PRKCD (protein kinase C delta [Source:HGNC Symbol;Acc:HGNC:9399])

HSP 1 Score: 72.7886 bits (177), Expect = 2.463e-14
Identity = 47/142 (33.10%), Postives = 72/142 (50.70%), Query Frame = 1
Query: 1549 QILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKI-IPGQKRNEI---NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISV 1962
            +I+ GL  LHD GI+Y +L + +ILLD  G +K+A   + K  I G  R        DY+APEI+  + +N   D WSFG++L E++ G+   F    E   E  F  I      +P  I +  + ++   L  +P  R+ V
Sbjct:   96 EIVSGLQFLHDQGIIYRDLKLDNILLDKDGHVKIADFGMCKENIVGDVRAGTFCGTPDYIAPEIVIGQKYNCSVDWWSFGVLLYEMLIGQS-PFRGDDE---EELFESIRTSVPYYPRWITKDSRDILPLLLEREPMKRLGV 233          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92])

HSP 1 Score: 73.9442 bits (180), Expect = 3.773e-14
Identity = 50/159 (31.45%), Postives = 82/159 (51.57%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDEL--TMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTE------AKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++    +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N             KN     + +Y K          FK  +DSCLN+DP  R + + LL++KF
Sbjct:  128 REILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPTLEGNYSKA---------FKEFVDSCLNKDPQFRPTAKELLKHKF 277          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008193.1 (pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-1 gene:ENSPMAG00000007385.1 transcript:ENSPMAT00000008193.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 3.947e-14
Identity = 46/168 (27.38%), Postives = 80/168 (47.62%), Query Frame = 1
Query: 1510 RIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINK-------DYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEA------KNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974
            R  S + ++ W R I  G++ LH H I++ +L   ++L+    ++K++     K    + R +  +        ++APE++ N+P + K D+WSFG++L E++TG+       + A       N  H           P S  E FK ++  C N  P NR S R +L
Sbjct:   95 RRISPELLVGWTRGIARGMSYLHLHKIIHRDLKSPNVLITHDDEVKISDFGTSK----EMREKSTRMSFAGTVAWMAPEVIRNEPVSEKVDIWSFGVVLWELLTGEIPYRDVDSSAIIWGVGSNSLHL--------PIPASCPEGFKILLTQCWNSKPRNRPSFRQIL 250          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 70.8626 bits (172), Expect = 1.591e-13
Identity = 46/176 (26.14%), Postives = 80/176 (45.45%), Query Frame = 1
Query: 1486 FKAVDGKTRIA-SNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSIN--ERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            FK ++ +  +  S D+++ W  Q+   L  +HD  I++ ++   +I L   G ++L    I +++      E+ +       YL+PEI +NKP+N K+D+W+ G +L E+ T          EA N  +      +    PVS +     +  +   L  DP  R  V VLL    
Sbjct:   89 FKRINAQKGVLFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGIARVL--NSTTELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCT-----LRHAFEAGNMKNLVLKIIRGSFPPVSAHYSSELRSTLSGLLRRDPRARPPVAVLLSRPL 257          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Match: map2k7 (mitogen-activated protein kinase kinase 7 [Source:ZFIN;Acc:ZDB-GENE-090312-186])

HSP 1 Score: 70.4774 bits (171), Expect = 3.338e-13
Identity = 57/191 (29.84%), Postives = 98/191 (51.31%), Query Frame = 1
Query: 1441 VSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHD-HGIVYDELTMSHILLDSKGDIKLASINI-GKII--PGQKRNEINKDYLAPEILD-----NKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            V ++MELM    ++  K + G   I  N  + K    I++ L+ L + HG+++ ++  S+ILLDS+G IKL    I G+++    + R      Y+APE +D     +  ++I+ADVWS GI L+E+ TG+    + KT+ +  +   + D       +  +  F+  +  CL +D   R     LLE+ F
Sbjct:  148 VFIAMELMGTCAEKLKKRIQGP--IPEN-ILGKMTVAIVKALSYLKEKHGVIHRDVKPSNILLDSRGRIKLCDFGISGRLVDSKAKTRGAGCAAYMAPERIDPPDPTHPDYDIRADVWSLGISLVELATGQFPYQNCKTDFEVLTKVLQEDPPLLPSDMGFSLDFQAFVKDCLTKDHRKRPKYNKLLEHAF 335          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: MKK2 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p; MKK2 has a paralog, MKK1, that arose from the whole genome duplication [Source:SGD;Acc:S000006061])

HSP 1 Score: 73.9442 bits (180), Expect = 3.627e-14
Identity = 56/216 (25.93%), Postives = 104/216 (48.15%), Query Frame = 1
Query: 1393 SERFVRIFAIYKGEGLVSV--SMELMAI-SLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP---------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            S+  V+ + ++  E   S+  +ME M   SL+  +K +  +    S   + K    +L GL+ LH+  +++ ++   +ILL+ KG+IKL    +     G+  N +         Y+APE +  +P+++  DVWS G+ LLE+  G+ F F +    +N +    +       P         +S ++ F+  ID CL +D   R S R +L++ +
Sbjct:  270 SDYIVQYYGMFTDEQSSSIYIAMEYMGGKSLEATYKNLLKRGGRISERVIGKIAESVLRGLSYLHERKVIHRDIKPQNILLNEKGEIKLCDFGVS----GEAVNSLAMTFTGTSFYMAPERIQGQPYSVTCDVWSLGLTLLEVAGGR-FPFESDKITQNVAPIELLTMILTFSPQLKDEPELDISWSKTFRSFIDYCLKKDARERPSPRQMLKHPW 480          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: PKH1 (Serine/threonine protein kinase; involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; contains a PH-like domain; redundant with Pkh2p; PKH1 has a paralog, PKH2, that arose from the whole genome duplication [Source:SGD;Acc:S000002898])

HSP 1 Score: 71.633 bits (174), Expect = 2.840e-13
Identity = 45/175 (25.71%), Postives = 85/175 (48.57%), Query Frame = 1
Query: 1522 NDEVIKWY-RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEIN-----------------KDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF*H 1992
            N+   ++Y  QI++ +  LH+ GI++ ++   +ILLD    +KL      KI+P +  N  +                  +Y++PE+L++   + + D+W+FG IL +++ GK   F A  E        KI   +Y F     +  K ++   L  DPN+R++++ +  + F H
Sbjct:  222 NETCARYYASQIIDAVDSLHNIGIIHRDIKPENILLDKNMKVKLTDFGTAKILPEEPSNTADGKPYFDLYAKSKSFVGTAEYVSPELLNDNYTDSRCDIWAFGCILYQMLAGKP-PFKAANEYLTFQKVMKI---QYAFTAGFPQIVKDLVKKLLVRDPNDRLTIKQIKAHLFFH 392          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: MKK1 (MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication [Source:SGD;Acc:S000005757])

HSP 1 Score: 70.0922 bits (170), Expect = 4.823e-13
Identity = 55/216 (25.46%), Postives = 102/216 (47.22%), Query Frame = 1
Query: 1393 SERFVRIFAIYKGE--GLVSVSMELMAI-SLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP---------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            SE  VR + ++  +    + ++ME M   SL   +K +  +    S   + K    +L GL+ LH+  +++ ++   +ILL+  G +KL    +     G+  N +         Y+APE +  +P+++ +DVWS G+ +LE+  GK F  S++  A N + F  + +     P         +  +  FK  ID CL +D   R S R ++ + +
Sbjct:  277 SEYIVRYYGMFTDDENSSIYIAMEYMGGRSLDAIYKNLLERGGRISEKVLGKIAEAVLRGLSYLHEKKVIHRDIKPQNILLNENGQVKLCDFGVS----GEAVNSLATTFTGTSFYMAPERIQGQPYSVTSDVWSLGLTILEVANGK-FPCSSEKMAANIAPFELLMWILTFTPELKDEPESNIIWSPSFKSFIDYCLKKDSRERPSPRQMINHPW 487          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700])

HSP 1 Score: 69.707 bits (169), Expect = 5.438e-13
Identity = 45/145 (31.03%), Postives = 69/145 (47.59%), Query Frame = 1
Query: 1531 VIKWYR-QILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEIN-KDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRIS 1959
            V K+Y  ++   L  LH   I+Y +L   +ILLD  G IK+      K +P          DY+APE++  KP+N   D WSFGI++ E++ G    + + T    E    KI   +  FP   NE  K ++   +  D + R+ 
Sbjct:  186 VAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYE----KILNAELRFPPFFNEDVKDLLSRLITRDLSQRLG 326          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Match: GIN4 (Protein kinase involved in bud growth and assembly of the septin ring; proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Hsl1p; GIN4 has a paralog, KCC4, that arose from the whole genome duplication [Source:SGD;Acc:S000002915])

HSP 1 Score: 67.0106 bits (162), Expect = 7.537e-12
Identity = 50/177 (28.25%), Postives = 86/177 (48.59%), Query Frame = 1
Query: 1528 EVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEI---NKDYLAPEILDNKPW-NIKADVWSFGIILLEIITGKC-FNFSAKTEAKNESHFFKIDYKKYIFPVS--INERFKGVIDSCLNEDPNNRISVRVLLENKF*H*F*RFPIIFAYEGCR 2037
            E I+++RQI+ G++  H  GIV+ +L   ++LLD K +IK+A   +  +    K  E    +  Y APEI+   P+    +DVWS G+IL  ++TG+  F+   + +    +   K+   ++  P    I+   + +I   L  DP  RI  R +L         + P++  Y   R
Sbjct:  132 EAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYNIKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFD---EEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDIL---------KHPLLQKYPSIR 296          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO49822 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG20])

HSP 1 Score: 82.8037 bits (203), Expect = 2.182e-17
Identity = 53/174 (30.46%), Postives = 91/174 (52.30%), Query Frame = 1
Query: 1486 FKAVDGKTRIA-SNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQ---KRNEINKDY-LAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHF-FKIDYKKY-IFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +K ++G+  IA S D+V+ W+ QI  GL  +HD  I++ ++   +I L   G IK+    I +++       R  I   Y L+PEI++N+P+N K+D+WS G +L E++T          EA N  +   KI    Y   P+  +   + ++   L  +P++R SV  +L+  F
Sbjct:   89 YKKINGQRGIAFSEDQVMDWFVQICLGLKHVHDRKILHRDIKSQNIFLTRHGIIKMGDFGIARVLHSTVELARTCIGTPYYLSPEIVENRPYNNKSDIWSLGCVLYEMLT-----LKHAFEAGNMKNLVLKIIRGSYPPIPLRYSADIRMLVAQLLKRNPHDRPSVNTVLKKNF 257          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO35437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH0])

HSP 1 Score: 78.9518 bits (193), Expect = 6.249e-16
Identity = 62/249 (24.90%), Postives = 119/249 (47.79%), Query Frame = 1
Query: 1255 LIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERF---VRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            L +EK + YI   +V         +K+ +  S++  +LR+   + +  R    +R+F  +  +  V + +E       E +K +    +        K+ RQ+ + LA  H   +++ ++   ++LL+ KGDIK+A        P  +R  +    DYL PE+++ K  + K D+WS G++  E + GK   F A  E  NE+ + +I      FP  ++   + +I   L  +PNNR+ ++ +L + +
Sbjct:   64 LAREKKSKYIVALKVL--------FKSQLQKSNVEHQLRREIEIQSHLRHNNILRLFGYFYDDTRVYLILEYAPRG--ELYKELTACEKF-DEKRAAKYIRQLADALAYCHSKKVIHRDIKPENLLLNYKGDIKIADFGWSVHAPSSRRTTLCGTLDYLPPEMIEGKEHDEKVDLWSIGVLCYEFLVGKP-PFEA--EGHNET-YRRISRVDLRFPSHVSPGARDLISKLLQHNPNNRLPLKAVLNHPW 297          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO45846 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RRL1])

HSP 1 Score: 72.7886 bits (177), Expect = 5.884e-14
Identity = 42/160 (26.25%), Postives = 81/160 (50.62%), Query Frame = 1
Query: 1519 SNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASIN----IGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            S ++V    R +L+ L  LH  G+++ ++    ILL S G +KL+       + + +P +K       ++APE++  KP+  + D+WS GI++LE++ G+   F+ +   +       ++      P+ I+ R +  +D+ L  DP  R +   LL + F
Sbjct:  121 SEEQVACVCRAVLKALTFLHSQGVIHRDIKSDSILLTSNGTVKLSDFGFCAQVTEDMPRRKSLVGTPYWMAPEVISRKPYGTEVDIWSLGIMVLEMVDGEPPYFN-EPPLQAMRKLRDLEPPTSRNPIQISPRLQSFLDNALIRDPLYRATAFELLNHPF 279          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO35585 (Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7SL27])

HSP 1 Score: 73.1738 bits (178), Expect = 2.230e-13
Identity = 38/122 (31.15%), Postives = 68/122 (55.74%), Query Frame = 1
Query: 1540 WYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGK--IIPGQKRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFK-IDYKKYIFPV 1890
            +  +++  L  LH +G++Y +L + ++LLD+ G IKLA   + K  + PG+         DY+APEIL  +P+    D W+ G+++ E++ G+        EA+NE   F+ I +   ++PV
Sbjct:  487 YAAEVVLALQFLHQNGVIYRDLKLDNVLLDADGHIKLADFGMCKENMAPGKTTTTFCGTPDYIAPEILQEQPYGFSVDWWALGVLMYEMMAGQ-----PPFEAENEEDLFESILHDDVLYPV 603          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Match: EDO31934 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SWI4])

HSP 1 Score: 72.0182 bits (175), Expect = 2.753e-13
Identity = 43/163 (26.38%), Postives = 85/163 (52.15%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKD--------YLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFP--------VSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R++L+GL  LH    ++ ++  +++L+   GD+KLA   +     GQ  + +NK         ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++    ++ P         + ++ FK  +  CLN+DPN+R + + LL+++F
Sbjct:  113 REVLKGLDYLHTEKKLHRDIKAANVLMSETGDVKLADFGVA----GQLTDTLNKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAIELAKGEPPN--------SDLHPMRV---LFLIPKNNPPELTGNFSKAFKEFVSLCLNKDPNDRPTAKELLKHRF 260          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729])

HSP 1 Score: 75.8702 bits (185), Expect = 4.395e-14
Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P      ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGPYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: stk25b (serine/threonine kinase 25 [Source:NCBI gene;Acc:101157729])

HSP 1 Score: 75.8702 bits (185), Expect = 4.616e-14
Identity = 47/156 (30.13%), Postives = 86/156 (55.13%), Query Frame = 1
Query: 1546 RQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINI-GKIIPGQ-KRNEI--NKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDY--KKYIFPV---SINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            R+IL+GL  LH    ++ ++  +++LL  +GD+KLA   + G++   Q KRN       ++APE++    ++ KAD+WS GI  +E+  G+  N        ++ H  ++ +   K   P      ++ FK  +++CLN+DP  R + + LL++KF
Sbjct:  122 REILKGLEYLHSERKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPN--------SDLHPMRVLFLIPKNTPPTLEGPYSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985])

HSP 1 Score: 76.6406 bits (187), Expect = 8.068e-14
Identity = 50/161 (31.06%), Postives = 83/161 (51.55%), Query Frame = 1
Query: 1531 VIKWYRQILEGLACLHDHGIVYDELTMSHILLDS-KGDIKLASINIGK----IIPGQKRNEINKDYLAPEILDNKP--WNIKADVWSFGIILLEIITGKC--FNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +I + +Q+LEGL  LHD+ IV+ ++   ++L+++  G +K++     K    I P  +       Y+APEI+D  P  +   AD+WS G  ++E+ TGK       +   A  +   FKI  K    P  +++  KG I SC   +P+NR +   LL + F
Sbjct:  677 IIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFAGTLQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPK---VPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTF 834          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: si:ch211-1i11.3 (mitogen-activated protein kinase kinase kinase 5 [Source:NCBI gene;Acc:101167985])

HSP 1 Score: 76.2554 bits (186), Expect = 8.389e-14
Identity = 50/161 (31.06%), Postives = 83/161 (51.55%), Query Frame = 1
Query: 1531 VIKWYRQILEGLACLHDHGIVYDELTMSHILLDS-KGDIKLASINIGK----IIPGQKRNEINKDYLAPEILDNKP--WNIKADVWSFGIILLEIITGKC--FNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            +I + +Q+LEGL  LHD+ IV+ ++   ++L+++  G +K++     K    I P  +       Y+APEI+D  P  +   AD+WS G  ++E+ TGK       +   A  +   FKI  K    P  +++  KG I SC   +P+NR +   LL + F
Sbjct:  733 IIFYTKQVLEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFAGTLQYMAPEIIDQGPRGYGKPADIWSLGCTIIEMATGKTPFHELGSPQAAMFKVGMFKIHPK---VPECMSDEAKGFIMSCFEPNPDNRATAAELLMDTF 890          
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Match: map2k7 (mitogen-activated protein kinase kinase 7 [Source:NCBI gene;Acc:101164950])

HSP 1 Score: 73.1738 bits (178), Expect = 3.267e-13
Identity = 57/192 (29.69%), Postives = 100/192 (52.08%), Query Frame = 1
Query: 1441 VSVSMELMAISLKEHFKAVDGKTRIASNDEVI-KWYRQILEGLACLHD-HGIVYDELTMSHILLDSKGDIKLASINI-GKII--PGQKRNEINKDYLAPEILD----NKP-WNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            V ++MELM    ++  K + G       ++++ K    I++ L  L + HG+++ ++  S+ILLD+KG IKL    I G+++    + R+     Y+APE +D     KP ++I+ADVWS GI L+E+ TG+    + KT+ +  +   + D       +  +  F+  +  CL +D   R     LLE+ F
Sbjct:  209 VFIAMELMGTCAEKLKKRIQGPI----PEQILGKMTVAIVKALLYLKEKHGVIHRDVKPSNILLDAKGQIKLCDFGISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKPDYDIRADVWSLGISLVELATGQFPYKNCKTDFEVLTKVLQEDPPLLPLGMGFSLDFQSFVKDCLTKDHRKRPKYHQLLEHSF 396          
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003862.1 (SMESG000003862.1)

HSP 1 Score: 948.732 bits (2451), Expect = 0.000e+0
Identity = 496/646 (76.78%), Postives = 551/646 (85.29%), Query Frame = 1
Query:   91 NVNGQEPIPVCSQNRPYRLFDSKCANFFEICTKQDDYECDQLQASCKQCPPSKITVKFLHDILRILNYXXXXXXXXXXXXXXXXXXXXXXENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEM-----EERP---------FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLLENKF 1986
            NVNGQEPI VCS+NRP+RL DSKCAN+  IC+KQDD +C+QLQ +CKQCPPS++TV  L +ILRI+ Y+L+N +I ILI N+V F LL+ ENRFK+ITKFC  L  KK+ N Y ++ SRK +   +N IGDFGTKLK RLPTENKVIELHVYGN+NVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGK ISDLNQILCKL +   + ++VKP     YS L +  +TL  A + DN +IV + +KPV+I F SIL++++ F  ELS  E VS+I+  ++QKFKSE+ VL++   +M S++FLFQYNID+ESQIKYCRF EM     E +P         FSI  +FKKQ L    KATD   N+EV +M+Y+LSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVI SCLNEDPNNRISVRVLLENKF
Sbjct:   15 NVNGQEPISVCSRNRPFRLSDSKCANYTGICSKQDDDQCNQLQNACKQCPPSEMTVIMLQEILRIVKYRLVNFLIAILIVNVVAFFLLVFENRFKIITKFCSLLCKKKQVNVYHLLQSRKGKTYYANCIGDFGTKLKLRLPTENKVIELHVYGNENVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKKISDLNQILCKLLDQSDLVIYVKPSDAANYSDLNNPDLTLVKAGVKDNDQIVAITKKPVKIMFSSILSNDENFNSELSNVERVSSILNIVEQKFKSED-VLIIGERDMISEQFLFQYNIDDESQIKYCRFNEMDAQDQEVKPLKESVGRLRFSIIGIFKKQELSQIYKATDNFNNKEVALMQYRLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIHSCLNEDPNNRISVRVLLENKF 659          
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1)

HSP 1 Score: 928.702 bits (2399), Expect = 0.000e+0
Identity = 482/656 (73.48%), Postives = 529/656 (80.64%), Query Frame = 1
Query:   22 MGYIVEFKAXXXXXXXXXXXXXXNVNGQEPIPVCSQNRPYRLFDSKCANFFEICTKQDDYECDQLQASCKQCPPSKITVKF--LHDILRILNYXXXXXXXXXXXXXXXXXXXXXXENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974
            MGYI+EFK                    EPI VCSQNRPY LFDSKCANFF+ICTKQDDYECDQLQASCKQCPPSKITVK+  ++ +++IL + ++  ++ I+            ENRFKLI          KKFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD  MT EAAKLCD  RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q  YCRFYE EER     S  ++F KQ      KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL   N +ERFV+I AIYKG   V+VSMELM++S+KE F  +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI   I G K ++ N  +LAPEI   K WNIKADVWSFG+ILLEIITGKCFNFSAK EA N+S+FFKIDY KYIFP SINERFKGVID CL EDPN RISV  LL
Sbjct:    1 MGYILEFK--------------------EPISVCSQNRPYTLFDSKCANFFDICTKQDDYECDQLQASCKQCPPSKITVKYQLMNIMIQILTFNIVIFVLLII------------ENRFKLI----------KKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIITGKCFNFSAKKEALNDSNFFKIDYTKYIFPRSINERFKGVIDRCLVEDPNYRISVHELL 614          
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1)

HSP 1 Score: 837.41 bits (2162), Expect = 0.000e+0
Identity = 435/598 (72.74%), Postives = 480/598 (80.27%), Query Frame = 1
Query:   22 MGYIVEFKAXXXXXXXXXXXXXXNVNGQEPIPVCSQNRPYRLFDSKCANFFEICTKQDDYECDQLQASCKQCPPSKITVKF--LHDILRILNYXXXXXXXXXXXXXXXXXXXXXXENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIIT 1800
            MGYI+EFK                    EPI VCSQNRPY LFDSKCANFF+ICTKQDDYECDQLQASCKQCPPSKITVK+  ++ +++IL + ++  ++ I+            ENRFKLI          KKFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD  MT EAAKLCD  RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q  YCRFYE EER     S  ++F KQ      KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL   N +ERFV+I AIYKG   V+VSMELM++S+KE F  +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI   I G K ++ N  +LAPEI   K WNIKADVWSFG+ILLEIIT
Sbjct:    1 MGYILEFK--------------------EPISVCSQNRPYTLFDSKCANFFDICTKQDDYECDQLQASCKQCPPSKITVKYQLMNIMIQILTFNIVIFVLLII------------ENRFKLI----------KKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIIT 556          
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1)

HSP 1 Score: 823.543 bits (2126), Expect = 0.000e+0
Identity = 415/526 (78.90%), Postives = 450/526 (85.55%), Query Frame = 1
Query:  406 TKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974
            + +KFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD  MT EAAKLCD  RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q  YCRFYE EER     S  ++F KQ      KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL   N +ERFV+I AIYKG   V+VSMELM++S+KE F  +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI   I G K ++ N  +LAPEI   K WNIKADVWSFG+ILLEIITGKCFNFSAK EA N+S+FFKIDY KYIFP SINERFKGVID CL EDPN RISV  LL
Sbjct:   67 SNEKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIITGKCFNFSAKKEALNDSNFFKIDYTKYIFPRSINERFKGVIDRCLVEDPNYRISVHELL 592          
BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Match: SMESG000003878.1 (SMESG000003878.1)

HSP 1 Score: 822.772 bits (2124), Expect = 0.000e+0
Identity = 415/526 (78.90%), Postives = 450/526 (85.55%), Query Frame = 1
Query:  406 TKKKFNTYQIIHSRKREIELSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYKIMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIRRDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYMTLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIARLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERP---FSISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELRKLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIASNDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGKIIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFSAKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVLL 1974
            + +KFNTYQIIHSRKREIE SNFIGDFGTKLKFRLPTENKVIELHVYGNDNVV IKK +CKKWPKA+SDSYKIMKLIYKGKCLDDN+NILS IGSHRGEILCQMDYSVNA+DILVLRVAGIRRDTELVQINKGKNISDL QILCKLFNC+GISMFVKP K+EKYS LKD  MT EAAKLCD  RIVVVKEKPVRIKFQSILNDEDPFVIE SRTESVSAI ARLKQKFKSENFVLMMNNC M+SD+FLFQYNIDEE+Q  YCRFYE EER     S  ++F KQ      KATD ITNREV VMEYKLSDWKAF+N+S LI ELRKL   N +ERFV+I AIYKG   V+VSMELM++S+KE F  +DGK + ASN++VIKW RQILEGL CLHD+GI YDELTMS+ILLD+K DIKLA+INI   I G K ++ N  +LAPEI   K WNIKADVWSFG+ILLEIITGKCFNFSAK EA N+S+FFKIDY KYIFP SINERFKGVID CL EDPN RISV  LL
Sbjct:   51 SNEKFNTYQIIHSRKREIEFSNFIGDFGTKLKFRLPTENKVIELHVYGNDNVVNIKKHICKKWPKAQSDSYKIMKLIYKGKCLDDNQNILSFIGSHRGEILCQMDYSVNANDILVLRVAGIRRDTELVQINKGKNISDLKQILCKLFNCKGISMFVKPSKDEKYSPLKDLDMTFEAAKLCDKVRIVVVKEKPVRIKFQSILNDEDPFVIEQSRTESVSAIFARLKQKFKSENFVLMMNNCIMKSDRFLFQYNIDEETQTTYCRFYEREERKRGFHSFKSLFIKQEFSKLGKATDNITNREVAVMEYKLSDWKAFMNSSGLINELRKLDAANGNERFVQIIAIYKGLESVTVSMELMSMSVKERFATIDGKVKKASNEQVIKWSRQILEGLVCLHDNGIAYDELTMSNILLDNKDDIKLATINIDTAIHGLKFDDNNGMHLAPEIRKGKLWNIKADVWSFGVILLEIITGKCFNFSAKKEALNDSNFFKIDYTKYIFPRSINERFKGVIDRCLVEDPNYRISVHELL 576          
The following BLAST results are available for this feature:
BLAST of Serine/threonine protein kinase, putative vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
STK261.367e-1429.63serine/threonine kinase 26 [Source:HGNC Symbol;Acc... [more]
STK262.689e-1429.63serine/threonine kinase 26 [Source:HGNC Symbol;Acc... [more]
STK262.931e-1429.63serine/threonine kinase 26 [Source:HGNC Symbol;Acc... [more]
STK253.108e-1430.13serine/threonine kinase 25 [Source:HGNC Symbol;Acc... [more]
STK263.256e-1429.63serine/threonine kinase 26 [Source:HGNC Symbol;Acc... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
max-26.468e-1429.01Serine/threonine-protein kinase max-2 [Source:Uni... [more]
max-23.077e-1329.01Serine/threonine-protein kinase max-2 [Source:Uni... [more]
max-24.797e-1329.01Serine/threonine-protein kinase max-2 [Source:Uni... [more]
max-24.862e-1329.01Serine/threonine-protein kinase max-2 [Source:Uni... [more]
max-25.393e-1329.01Serine/threonine-protein kinase max-2 [Source:Uni... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inaC1.152e-1433.33gene:FBgn0004784 transcript:FBtr0087047[more]
GckIII7.000e-1428.22gene:FBgn0266465 transcript:FBtr0083399[more]
aPKC1.325e-1330.94gene:FBgn0261854 transcript:FBtr0303432[more]
aPKC1.377e-1330.94gene:FBgn0261854 transcript:FBtr0329888[more]
aPKC1.403e-1330.94gene:FBgn0261854 transcript:FBtr0303429[more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk25b1.578e-1430.77serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-G... [more]
stk25b1.680e-1430.77serine/threonine kinase 25b [Source:ZFIN;Acc:ZDB-G... [more]
stk261.378e-1328.22serine/threonine protein kinase 26 [Source:ZFIN;Ac... [more]
stk24a1.644e-1330.43serine/threonine kinase 24a (STE20 homolog, yeast)... [more]
map2k71.738e-1330.37mitogen-activated protein kinase kinase 7 [Source:... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk257.644e-1529.81serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk258.399e-1529.81serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
stk259.664e-1529.81serine/threonine kinase 25 [Source:NCBI gene;Acc:5... [more]
cpvl1.106e-1429.82carboxypeptidase, vitellogenic-like [Source:Xenbas... [more]
cpvl1.110e-1429.82carboxypeptidase, vitellogenic-like [Source:Xenbas... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Stk261.582e-1430.25serine/threonine kinase 26 [Source:MGI Symbol;Acc:... [more]
Stk261.749e-1430.25serine/threonine kinase 26 [Source:MGI Symbol;Acc:... [more]
Stk254.445e-1330.13serine/threonine kinase 25 (yeast) [Source:MGI Sym... [more]
Prkci4.458e-1330.00protein kinase C, iota [Source:MGI Symbol;Acc:MGI:... [more]
Prkcd6.871e-1331.03protein kinase C, delta [Source:MGI Symbol;Acc:MGI... [more]
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BLAST of Serine/threonine protein kinase, putative vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9S7U9|M2K2_ARATH9.546e-1426.02Mitogen-activated protein kinase kinase 2 OS=Arabi... [more]
sp|Q99JT2|STK26_MOUSE1.106e-1330.25Serine/threonine-protein kinase 26 OS=Mus musculus... [more]
sp|P13677|KPC2_DROME1.155e-1333.33Protein kinase C, eye isozyme OS=Drosophila melano... [more]
sp|Q9P289|STK26_HUMAN1.408e-1329.63Serine/threonine-protein kinase 26 OS=Homo sapiens... [more]
sp|Q55GC2|DST2_DICDI1.999e-1333.33Serine/threonine-protein kinase dst2 OS=Dictyostel... [more]
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BLAST of Serine/threonine protein kinase, putative vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A371IGI61.621e-1529.78Mitogen-activated protein kinase kinase kinase NPK... [more]
C4M8G82.522e-1528.51Serine/threonine protein kinase, putative OS=Entam... [more]
A0A5K1UP002.522e-1528.51Serine threonine protein kinase putative OS=Entamo... [more]
A0A4P9XQV24.736e-1525.99Kinase-like domain-containing protein (Fragment) O... [more]
K2HFC61.729e-1428.09Serine/threonine protein kinase, putative OS=Entam... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk25b2.081e-1430.77serine/threonine-protein kinase 25-like [Source:NC... [more]
stk25b2.617e-1430.77serine/threonine-protein kinase 25-like [Source:NC... [more]
stk267.027e-1427.78serine/threonine kinase 26 [Source:NCBI gene;Acc:1... [more]
stk261.174e-1327.78serine/threonine kinase 26 [Source:NCBI gene;Acc:1... [more]
stk25a2.340e-1330.13serine/threonine-protein kinase 25 [Source:NCBI ge... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PRKCD2.463e-1433.10protein kinase C delta [Source:HGNC Symbol;Acc:HGN... [more]
stk25a3.773e-1431.45serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-G... [more]
ENSPMAT00000008193.13.947e-1427.38pep scaffold:Pmarinus_7.0:GL476850:102262:127365:-... [more]
ENSPMAT00000007414.11.591e-1326.14pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1... [more]
map2k73.338e-1329.84mitogen-activated protein kinase kinase 7 [Source:... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5
Match NameE-valueIdentityDescription
MKK23.627e-1425.93MAPKK involved in the protein kinase C signaling p... [more]
PKH12.840e-1325.71Serine/threonine protein kinase; involved in sphin... [more]
MKK14.823e-1325.46MAPKK involved in the protein kinase C signaling p... [more]
TPK15.438e-1331.03cAMP-dependent protein kinase catalytic subunit; p... [more]
GIN47.537e-1228.25Protein kinase involved in bud growth and assembly... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO498222.182e-1730.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO354376.249e-1624.90Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO458465.884e-1426.25Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO355852.230e-1331.15Protein kinase C [Source:UniProtKB/TrEMBL;Acc:A7S... [more]
EDO319342.753e-1326.38Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
stk25b4.395e-1430.13serine/threonine kinase 25 [Source:NCBI gene;Acc:1... [more]
stk25b4.616e-1430.13serine/threonine kinase 25 [Source:NCBI gene;Acc:1... [more]
si:ch211-1i11.38.068e-1431.06mitogen-activated protein kinase kinase kinase 5 [... [more]
si:ch211-1i11.38.389e-1431.06mitogen-activated protein kinase kinase kinase 5 [... [more]
map2k73.267e-1329.69mitogen-activated protein kinase kinase 7 [Source:... [more]
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BLAST of Serine/threonine protein kinase, putative vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000003862.10.000e+076.78SMESG000003862.1[more]
SMESG000003878.10.000e+073.48SMESG000003878.1[more]
SMESG000003878.10.000e+072.74SMESG000003878.1[more]
SMESG000003878.10.000e+078.90SMESG000003878.1[more]
SMESG000003878.10.000e+078.90SMESG000003878.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035587 ID=SMED30035587|Name=Serine/threonine protein kinase, putative|organism=Schmidtea mediterranea sexual|type=transcript|length=2322bp
GCTAATTGAATTAATCGTGAAATGGGCTATATCGTGGAATTTAAGGCAAT
AGAAATTATTTTAGGGATATTACATTTATTTATTTTATTAAATGTGAATG
GCCAGGAACCGATACCAGTTTGTTCACAGAATCGCCCGTATAGACTATTT
GATAGCAAATGCGCAAACTTTTTTGAGATTTGTACAAAACAAGATGATTA
TGAGTGCGATCAATTGCAAGCTTCGTGCAAACAATGCCCTCCGAGCAAAA
TAACAGTAAAATTTCTACATGATATATTGAGAATTCTCAATTATCAATTG
ATGAATATTATGATCCAAATTTTGATTTTCAATATAGTCATCTTCGTTTT
GCTGATCATTGAGAATCGGTTCAAGTTGATCACAAAATTCTGTTTCGGAT
TGTTCACAAAAAAAAAATTTAATACTTATCAAATAATTCACAGCAGGAAG
AGGGAAATTGAGTTGTCGAATTTTATTGGAGATTTTGGGACAAAATTGAA
GTTCCGATTACCTACAGAAAACAAGGTGATAGAGCTACATGTTTATGGCA
ATGACAATGTTGTCAAAATAAAGAAACGTGTTTGCAAGAAGTGGCCCAAA
GCTAAATCAGATAGTTACAAAATAATGAAATTGATATATAAAGGGAAATG
CCTTGATGACAATGAGAATATTTTGTCACTCATTGGGTCACACAGAGGTG
AAATATTGTGCCAGATGGATTACTCTGTGAATGCCAGTGACATTCTCGTT
CTCCGAGTGGCTGGCATCAGGCGAGACACTGAGCTCGTTCAAATTAATAA
GGGGAAAAATATTTCTGATCTGAATCAGATCTTGTGCAAATTATTCAATT
GCGAAGGCATTTCCATGTTTGTGAAACCTTTCAAAAATGAGAAATATTCT
CTTTTGAAAGATTTTTATATGACTCTGGAAGCCGCCAAATTGTGTGACAA
TTCTCGCATTGTGGTAGTCAAAGAGAAACCCGTGAGAATTAAATTCCAAT
CAATCCTTAATGATGAAGATCCTTTTGTCATTGAGCTGTCAAGAACTGAA
TCCGTTTCGGCAATCATTGCTAGACTCAAACAAAAGTTTAAATCTGAAAA
TTTTGTTTTAATGATGAATAATTGCAATATGGAATCAGATAAATTTCTGT
TCCAATATAATATTGATGAGGAGAGTCAGATTAAATATTGCAGATTTTAT
GAGATGGAGGAGAGGCCATTTAGCATTTCTAACATGTTTAAGAAACAAGG
GTTATTGATAAAGGAAAAAGCAACGGATTATATCACCAATCGAGAGGTTA
CTGTGATGGAATATAAATTATCCGATTGGAAGGCTTTTATAAACAATTCT
AGTTTGATAAAGGAGCTGAGAAAACTCACAGTAATGAATGCAAGTGAAAG
ATTTGTGCGGATATTTGCCATATATAAAGGCGAGGGGTTGGTATCTGTGT
CCATGGAATTGATGGCGATATCATTGAAAGAACATTTTAAAGCTGTTGAT
GGCAAAACCAGAATAGCCTCAAATGATGAAGTTATTAAATGGTATCGACA
AATTCTTGAAGGCCTCGCCTGTCTTCATGATCACGGCATTGTATATGATG
AGCTGACAATGTCTCACATTCTTCTGGATAGCAAAGGGGACATCAAGCTA
GCCAGCATCAATATTGGTAAAATAATTCCTGGACAAAAAAGAAATGAAAT
AAATAAAGATTATCTTGCTCCTGAGATTTTGGACAATAAACCGTGGAACA
TTAAGGCCGACGTGTGGTCATTTGGAATCATTCTGCTGGAGATTATTACC
GGGAAATGTTTCAATTTCAGTGCAAAAACTGAAGCTAAAAATGAATCCCA
TTTCTTCAAAATTGATTATAAGAAATATATTTTCCCAGTATCAATAAATG
AAAGGTTCAAGGGCGTCATTGACAGCTGCTTGAATGAGGATCCGAATAAT
AGGATATCGGTGCGAGTGTTACTGGAAAATAAATTCTGACACTGATTTTA
AAGATTCCCGATAATTTTTGCATATGAAGGCTGCCGCTTGGTTTCATTAA
TTATTGTCGCAATATTTATCATTTGATTTAGACTGTTGATTCGGTTAACA
CTGGATTTTTATGTTCTTCGGTTTACGCTTTCAATACATTCTATCTATAA
CCATGTTCGTTTCTAACATTTATTTTCATTTTCTCTAAATGGATTGTTTT
GTAACTTTTCTTAATGCTTTATATATATGGCAACAAGTATTTTCGTGTCT
ATTATATAAGAACTGATTCTGAACAACTCTGATATGCTGAAATCAAAGAT
GATGTTTATTTTGCTTTTTTAC
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protein sequence of SMED30035587-orf-1

>SMED30035587-orf-1 ID=SMED30035587-orf-1|Name=SMED30035587-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=656bp
MGYIVEFKAIEIILGILHLFILLNVNGQEPIPVCSQNRPYRLFDSKCANF
FEICTKQDDYECDQLQASCKQCPPSKITVKFLHDILRILNYQLMNIMIQI
LIFNIVIFVLLIIENRFKLITKFCFGLFTKKKFNTYQIIHSRKREIELSN
FIGDFGTKLKFRLPTENKVIELHVYGNDNVVKIKKRVCKKWPKAKSDSYK
IMKLIYKGKCLDDNENILSLIGSHRGEILCQMDYSVNASDILVLRVAGIR
RDTELVQINKGKNISDLNQILCKLFNCEGISMFVKPFKNEKYSLLKDFYM
TLEAAKLCDNSRIVVVKEKPVRIKFQSILNDEDPFVIELSRTESVSAIIA
RLKQKFKSENFVLMMNNCNMESDKFLFQYNIDEESQIKYCRFYEMEERPF
SISNMFKKQGLLIKEKATDYITNREVTVMEYKLSDWKAFINNSSLIKELR
KLTVMNASERFVRIFAIYKGEGLVSVSMELMAISLKEHFKAVDGKTRIAS
NDEVIKWYRQILEGLACLHDHGIVYDELTMSHILLDSKGDIKLASINIGK
IIPGQKRNEINKDYLAPEILDNKPWNIKADVWSFGIILLEIITGKCFNFS
AKTEAKNESHFFKIDYKKYIFPVSINERFKGVIDSCLNEDPNNRISVRVL
LENKF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
PLANA:0003117parapharyngeal cell
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR000626Ubiquitin-like_dom
IPR011009Kinase-like_dom_sf
IPR029071Ubiquitin-like_domsf
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0005515protein binding
GO:0004674protein serine/threonine kinase activity
GO:0004702signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0016301kinase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
GO:0023014signal transduction by protein phosphorylation
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableTMHMMTMhelixcoord: 91..113