Cytochrome P450 2K1-like protein

Overview
NameCytochrome P450 2K1-like protein
Smed IDSMED30035502
Length (bp)2280
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Cytochrome P450 2K1-like protein (SMED30035502) t-SNE clustered cells

Violin plots show distribution of expression levels for Cytochrome P450 2K1-like protein (SMED30035502) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Cytochrome P450 2K1-like protein (SMED30035502) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Cytochrome P450 2K1-like protein (SMED30035502) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035502

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30035502h1SMcG0019223 Contig4575GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035502h1SMcG0021419 Contig4575GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
gutSMED30035502h1SMcG0021419 dd_Smed_v4_2083_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035502h1SMcG0021419 dd_Smed_v4_2083_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035502h1SMcG0021419 dd_Smed_v4_2083_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035502h1SMcG0021419 dd_Smed_v4_2083_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Category 4 cellSMED30035502h1SMcG0021419 dd_Smed_v4_2083_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2A13 (cytochrome P450 family 2 subfamily A member 13 [Source:HGNC Symbol;Acc:HGNC:2608])

HSP 1 Score: 245.743 bits (626), Expect = 2.818e-72
Identity = 154/441 (34.92%), Postives = 227/441 (51.47%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIK-EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHA--HFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            GP+  P IGN   +  E +++ L K + +YGP+F   +G R +VV+  +  + +AL ++   FSGR +      L    G+ F++GE     R F++  L+ FG GK+   E I  E  FL+  +  + G  I       +   NVI+ +    RF+ +   F  L   +       +F  T      + E +  + K L     ++Q F+E+     F A   EH +R    N   DFID FL    E   EK  N  F    LV     LF AG ET STTL +  +L+ K+ E++ KVH+EI  +IG  R P   D+  +PYT+AV+ EI R   ++P+ L HR+ ++++    F+PK + +FP L +  RD   +  P +F P+HFL  +  G  K S  D  VPFSIGKR C GE LARME F+FFT+IMQ F+ K
Sbjct:   36 GPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMML-----GSFQFTATSTGQLYEMFSSVMKHLP--GPQQQAFKELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQE--EEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFL--DKKGQFKKS--DAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFK 463
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2A6 (cytochrome P450 family 2 subfamily A member 6 [Source:HGNC Symbol;Acc:HGNC:2610])

HSP 1 Score: 244.202 bits (622), Expect = 9.513e-72
Identity = 149/450 (33.11%), Postives = 231/450 (51.33%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIK-EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILE--------EYPRIAKLLLRFSG-REQEFEEMHA--HFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            GP+  P IGN   +  E +++ L K + +YGP+F   +G R +VV+  +  + +AL ++   FSGR +      +    G++F++GE     R F++  L+DFG GK+   E I  E  FL+  +  + G  I       +   NVI+ +    RF+                 ++K F+  + +M  I +         Y   + ++    G ++Q F+ +     F A   EH +R    N   DFID FL    E   EK  N  F    LV     LF+ G ET STTL +  +L+ K+ E++ KVH+EI  +IG  R P   D+  +PY +AV+ EI R   V+P+SL  R+ ++++    F+PK + ++P L +  RD   +  P +F P+HFL ++  G  K S  D  VPFSIGKR C GE LARME F+FFT++MQ F++K
Sbjct:   36 GPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFD----------------YKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQE--EEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEK--GQFKKS--DAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK 463
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2U1 (cytochrome P450 family 2 subfamily U member 1 [Source:HGNC Symbol;Acc:HGNC:20582])

HSP 1 Score: 243.047 bits (619), Expect = 8.043e-71
Identity = 155/510 (30.39%), Postives = 256/510 (50.20%), Query Frame = 2 
Query:  293 KGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTF--------------------------KYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFK----FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            +G+ P  GP+ WPL+GN   +  P   FL ++++                           YG +F F +G   +VV+S    + +AL ++   FS R +  +   +    G++F   G  W  QR F+   L+ FG GK      I  E  ++  E+++         S+      N+I  L    RF+     FK    F++  +E    ++  +V I    P L   P        F    Q  +++ +  + II++H++  + EN  +DFIDM+L    E + +   N +F +  L  +I +LF+AG +TT+ +L W ++ M+ N ++Q+KVH+EI  +IG+ R P+++DK  +PYT+A + E+ R+T VVPL++PH   EN+ + G  IPK ++I PNL++ HRD  +W++P +FYP  FL D+     K    +  +PF IGKR C+GE LA+ME F+ F S+MQ F     +    D+   +  G  G   AP   ++    R
Sbjct:   57 RGIPP--GPTPWPLVGNFGHVLLP--PFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNIC---PWLYYLP-----FGPFKELRQIEKDITSFLKKIIKDHQESLDRENP-QDFIDMYLLHMEE-ERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKK----ETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPE----DSKKPLLTGRFGLTLAPHPFNITISRR 544
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2A7 (cytochrome P450 family 2 subfamily A member 7 [Source:HGNC Symbol;Acc:HGNC:2611])

HSP 1 Score: 239.58 bits (610), Expect = 4.336e-70
Identity = 152/441 (34.47%), Postives = 228/441 (51.70%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIK-EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHA--HFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            GP+  P IGN   +  E +   + K +  YGP+F   +G R +VV+  +  + +AL ++   FSGR +      +    G+ F++GE       FA+  L+DFG GK+   E I  E  FL++ I  + G  I       +   NVI+ +    RF+ +   F  L + +  +     F  T      + E +  + K L     ++Q F+ +     F A   EH +R    N  +DFID FL    E   EK  N  F    L+     LF+AG ET STTL +  +L+ K+ E++ KVH+EI  +IG  R P   D+  +PY +AV+ EI R   V+P+SL  R+ ++++    F+PK + +FP L +  RD   +  P +F P+HFL D+  G  K S  D  VPFSIGKR C GE LARME F+FFT++MQ F++K
Sbjct:   36 GPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGI-----FQFTSTSTGQLYEMFSSVMKHLP--GPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQE--EEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDK--GQFKKS--DAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLK 463
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Match: CYP2J2 (cytochrome P450 family 2 subfamily J member 2 [Source:HGNC Symbol;Acc:HGNC:2634])

HSP 1 Score: 228.024 bits (580), Expect = 1.170e-65
Identity = 152/452 (33.63%), Postives = 231/452 (51.11%), Query Frame = 2 
Query:  290 PKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTF--KYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQ----EFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            PK   P  GP   P +GN F + +   S L  Q F  KYG LF   +G    V+I+   ++ +AL      F  R    + + +   +G++ + G+ W  QR F L  L++FG GK+   E I  E   L + I+E  G+             N+I  +    RFE     F+ L   ++ V   +        +Y +   +P I K L    G  Q     ++++      +I++H+K +N   E  DFID +L+E  +         +F +  L+    +LF AG ETTSTTL WA++ MA   EIQ+KV  EI  +IG  + P+ + ++S+PYT AV+ E+ R+ +++PL++P  +  ++ + G  +PK ++I  NL A HRD   W  P  F P+HFL    NG  K    +  +PFSIGKR CLGE LAR E FIFFTS+MQ+F  +
Sbjct:   40 PKNYPP--GPWRLPFLGNFFLV-DFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLE--ASKTCQLYNV---FPWIMKFL---PGPHQTLFSNWKKLKLFVSHMIDKHRKDWN-PAETRDFIDAYLKEMSKHTGNPT--SSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFL---ENGQFKKR--EAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFR 472
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33C9 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O16482])

HSP 1 Score: 226.098 bits (575), Expect = 2.126e-65
Identity = 138/443 (31.15%), Postives = 228/443 (51.47%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPL--WSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNS-GILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRF-ERDTPNFKFLTANVE-RVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVE-NEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            GP+  PLIGNL +++ P   +    + T KYG ++ F +G R  +++SS + L +   + G  ++ +      ++    S G++ T+G +W   R FA+   +DFG GK R  + I  E   +    +++ G+ +    +F +   NVI ++    RF E     F+ + A       +  +F + +    P +        +L RF   ++ F E    F   IE HKK  + E  E  D+++ FL+E+ + +       +F+  QL  +  +L+ A   TTS T+TW        L+ Q K+H+E+  +IGSER  N +DK +LPYT A ++EI R  ++VPL+L H    ++ + G  IPK + +   +     D  V+  P+ F PE FL D+     K   +++LVPFS+GKRQCLGE LARME F+F  +   R++V
Sbjct:   28 GPTPLPLIGNLLSLRNPAPGYKAFARWTAKYGDIYTFWLGTRPYILVSSYEALKETFIKDGETYADKKPMAFQESFRGGSYGVVETNGPFWREHRRFAIHQFRDFGLGKDRMEQRIMLEVEDIFNNCDKTIGEGVDLTDIFDRAVGNVINQMLFGYRFDETRADEFRTIRAFFNFNSGEFASFSMRVQFFLPWMGYIMPGPTILDRFKKYQKGFTEF---FGTQIENHKKEIDFELEENSDYVEAFLKEQRKREASGDF-ESFSTKQLSNMCLDLWFAALMTTSNTMTWCFAYTLNYLDAQQKLHEELDRVIGSERHINTADKPNLPYTNAYINEIQRTANLVPLNLLHMTTRDTVLKGYNIPKGTGVVAQISTVMYDENVFPEPYIFKPERFLDDDG----KLKKVEQLVPFSVGKRQCLGEGLARMELFLFIANFFNRYRV 462
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33D1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O45659])

HSP 1 Score: 220.705 bits (561), Expect = 1.525e-63
Identity = 140/455 (30.77%), Postives = 230/455 (50.55%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKN-IIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPN----FKFLTANVERVAQNKNFIVTILLMY-------PILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVEN-EGEDFIDMFLRE--KYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFE 1633
            GP+  PL+GNL  +++  +   +K   ++GP+F F +  R  + I+S +++ +   + G  F+ +  N I  K L  N G+L T+GE W   R F L  L+D G GK    E I  E     K+I    G+ I   S+  +   NVI     N RFE +  +     K L   +  VA    + +  L+ +       P L +  +  K            EE+   F   +EEH+K  + +  E  D+++ +L+E  K E D +   + TF + QL  + F+L++AG +TT+ TLTW       N ++Q K+ +E+  +IG++R+   +DK  LPY  A ++E  R  +++P +L H    ++ I G  + K + +   +     D +++     F P  F+    NG +K   +DE++PFSIGKRQCLGE LARME F+FF +I  R+ V+ +
Sbjct:   28 GPTPLPLVGNLLQLQKFGYDIFHKWKKEFGPVFTFWLADRPFIFITSYEVMKETFVKDGDTFADKQLNQIDKKKLQRNYGVLDTNGEMWREHRRFTLSQLRDLGLGKDLMQEKILLEIEEQFKDINSHLGEEIDLPSVLDRGVGNVINLTLFNKRFETNQRDEFTYLKSLIDGLRDVASEFRYFIQFLVPWSSKIIPGPTLGDKTKGMK------------EELDVFFVKQVEEHRKEIDFDTVESYDYVEAYLKEQKKREADGD---HETFCNKQLYAMCFDLWMAGLQTTTVTLTWGFSFYLHNADVQLKIREELDRVIGNDRLITTADKNCLPYLTAFINETQRCANIIPFNLLHVATRDTVIEGYPVKKGTGVIAQIGTVMSDEQIFPDAHCFNPGRFI---ENGKLK--KVDEVIPFSIGKRQCLGEGLARMELFLFFANIFNRYDVQLD 462
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-23A1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:Q27465])

HSP 1 Score: 220.32 bits (560), Expect = 6.507e-63
Identity = 147/469 (31.34%), Postives = 237/469 (50.53%), Query Frame = 2 
Query:  311 HGPSGWPLIGNLFTIKEPLWSFLYKQTFK--YGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNS-GILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPK---CTVNVIAKLAMNMRFERDTPNF----KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFN---VENEGEDFIDMFL--REKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTM 1672
            +GP  W + GN+ +        +  Q++K  YG +F   +G   +V++S    + K   +    FS RW+N +  +++  S GI+  DG  W  QR FAL  L+DFG GK    ++I+ E   L+  +E+SCG       L P    C  N+I  +   +RF +D        + L      V Q    I+   + +P+  + P I     R  G + E  E        IE H+  +    +E E ED    ++   EK + + E V    F D QL  ++ +LF AG ETT TTL WA +LMAKN ++Q  V  E+ + IG   I  +  +  LPY QA ++EI R+ +++P++L   + E+ EI+G    K  +I P +     D E+++ P EF P  FL +++N       +DE +PFSIG+RQCLGE+LAR E ++ F +++Q F  +   +++ +    +T+
Sbjct:   58 NGPVPWLVAGNMPSFINVNNVDVLFQSWKQQYGGIFTVWIGPIPLVMVSDLPTIKKYFIQHADSFSNRWRNFVTDSIMEGSNGIVQIDGNKWREQRRFALHTLRDFGVGKPLMEQMITLEVTSLMNHMEKSCGLDGKELHLCPSIAVCVGNIINNMLFGLRFNQDNSYMHRLHQLLDDQSHTVMQP---IMGAYIAFPVTSKIPIINGEWNRLMGIKNELLEF---LETQIEGHRMNWKDEMIEQEPEDLTYAYMIEVEKRKRNGEDV--GFFDDQQLKMLLLDLFFAGMETTVTTLKWAFLLMAKNQKVQKNVQAEL-DSIGQPMI-EIQHRTRLPYVQATINEIQRIANILPINLLRTVAEDIEIDGYNFKKGDLIIPQISILMNDPEIFENPEEFNPSRFLDEDNN----VKKIDEFLPFSIGRRQCLGESLARAELYLVFANLIQNFNFEVADDVTTERVLGLTV 512
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33D3 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:G5EE22])

HSP 1 Score: 218.009 bits (554), Expect = 1.527e-62
Identity = 148/484 (30.58%), Postives = 247/484 (51.03%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLM-TRPSIPKGLKPLHGPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKT-LVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDT----PNFKFLTANVERVAQNKNFIVTILLMY-------PILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVEN-EGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            ++++I  ++ +YF       R ++P G +PL      P +GNL ++K  +P +        +YGP+F F M  +  V+I+S + + +   + G  +  +      K  L  N G+L T+G  W   R F L  L+D G GK    E I  E   L KE++   G+ I    L  +   NVI     N RF+ D      + K L   +  V     +++  L+ +       P L E  R  +            EE+   F + I+EH+   + +N E  DF++ +L+E+ + + +     TF + QL  ++F+L++AG  TT+ T+TW +     N E+Q K+ +E+  +IG++R+ + +DK  LPY QA + E  R  +++PL+L H    ++ I+G  I K + +   +     D +V+  P++F PE F+    NG  K+  +DE++PFSIGKRQCLGE LAR+E F+FF +I  R+ V
Sbjct:    2 LLLLIFSSIFLYFFYHFHWKRRNLPPGPRPL------PFLGNLLSLKTLKPGYEAFSNWKKEYGPIFTFWMANKPFVIIASYEKMKETFVKDGDTYVDKQLTHTEKERLGENYGVLDTNGHMWKEHRRFTLTQLRDLGLGKDLMQEKILMEVEELFKELDAHGGEEIDLPKLIDRSVGNVINLTLFNKRFDMDKRDEFAHLKSLIDGMRNVTSQFRYLIQYLVPWTSTVLPGPTLSEKVRAKR------------EELDDFFYSQIDEHRNEIDFDNTENLDFVEAYLKEQKKREEDGDFK-TFCNKQLCAMLFDLWIAGLMTTTMTMTWGLSYYLYNPEVQRKIREELDKVIGNDRLISTADKNDLPYLQAFVTETQRTANIIPLNLIHMTTRDTVIDGFPIQKGTGVIAQISTVMYDEKVFPEPYKFKPERFI---ENG--KFKKVDEVIPFSIGKRQCLGEGLARIELFLFFANIFNRYDV 461
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Match: cyp-33C1 (CYtochrome P450 family [Source:UniProtKB/TrEMBL;Acc:O44704])

HSP 1 Score: 216.853 bits (551), Expect = 4.471e-62
Identity = 156/508 (30.71%), Postives = 256/508 (50.39%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLM-TRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSF--LYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNS-----GILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPN-FKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLR--FSGREQEFEEMH-AHFRAIIEEHKKRFNVEN---EGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAP 1699
            +I+++   L IYF+ +L   R + P G  PL      P+ GNL +I  P   +    + T KYG ++ F +G    ++I++       +KE  I  +  + N +   +V  S     GI+ ++G  W   R FAL  ++DFG GK    E I  E   +   ++   G       +F     NV+ +L    RF     N ++ L   ++  A+    +   L M       P  AKLL    + G  + F +   A F   IE H+ R + E+   E  DF++ FL+E+   ++E   + T+++ QL+ V  +L+ AG  TT+ T+TWA+  +  + E+QDK+H+E+  +IGS+R+   +DK  LPY  A ++E  R  +++PL+L H    ++ I+G  IPK + +   +     + EV+  P+ F P+ F+  + NG +K   +DEL PFS+GKR C GE LARME F+F  + + R+K+   KE        M  G+ G + AP
Sbjct:    2 IIILLLTFLTIYFVYELYWKRRNFPPGPCPL------PVFGNLLSIANPPPGYKAFERWTKKYGDVYTFWIGNTPHIMINT----WDKIKETFIRDADTYTNKVVLPMVTLSRGGEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYRFMGPKENEYQELKHIIDSPAEIFGKLHIFLAM-----NIPIFAKLLPESLYEGPIKTFRDTTLAFFNKQIEAHRHRIDFEDLNSESTDFVETFLKEQKRRESEGD-SETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLITTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFI--DENGKLK--KVDELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIHPSKE----GLPSMAKGS-GPVVAP 484
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp18a1 (gene:FBgn0010383 transcript:FBtr0074610)

HSP 1 Score: 214.157 bits (544), Expect = 1.709e-60
Identity = 136/446 (30.49%), Postives = 223/446 (50.00%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGF-----GKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLRE----KYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            GP G P+IG L  +     +   +   +YG LF   +G +  VV+S  K++ +  + +   F+GR      +TL +  GI+ + G+ W  QR F    L+ FG      GKQ+  + I  E    +  +  S G+ +    +      NVI  L M+ RF  D P F+     +E   +    I T+  + P ++ +P I+    + +   Q   EM   ++ +I++HK+ F+  N   D +D +L E    K E  + ++ +    + QLV+VI +LF AG ET  TTL W  + M +N +   +V  E+  ++G  R+P + D + LP T++ + E  R +S+VPL+  H    + E+NG  IP  S + P + + H D  +W++P EF P  F+  E     K    +  +PF +G+R CLG+ LARME F+FF S M  F +
Sbjct:   56 GPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYI-PTMQCFPSISTAKNKIA---QNRAEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEG----KVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDI 489
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp18a1 (gene:FBgn0010383 transcript:FBtr0074609)

HSP 1 Score: 214.157 bits (544), Expect = 1.709e-60
Identity = 136/446 (30.49%), Postives = 223/446 (50.00%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGF-----GKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLRE----KYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            GP G P+IG L  +     +   +   +YG LF   +G +  VV+S  K++ +  + +   F+GR      +TL +  GI+ + G+ W  QR F    L+ FG      GKQ+  + I  E    +  +  S G+ +    +      NVI  L M+ RF  D P F+     +E   +    I T+  + P ++ +P I+    + +   Q   EM   ++ +I++HK+ F+  N   D +D +L E    K E  + ++ +    + QLV+VI +LF AG ET  TTL W  + M +N +   +V  E+  ++G  R+P + D + LP T++ + E  R +S+VPL+  H    + E+NG  IP  S + P + + H D  +W++P EF P  F+  E     K    +  +PF +G+R CLG+ LARME F+FF S M  F +
Sbjct:   56 GPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL-NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYI-PTMQCFPSISTAKNKIA---QNRAEMQRFYQDVIDDHKRSFD-PNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEG----KVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDI 489
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp303a1 (gene:FBgn0001992 transcript:FBtr0343812)

HSP 1 Score: 174.481 bits (441), Expect = 9.596e-47
Identity = 125/468 (26.71%), Postives = 228/468 (48.72%), Query Frame = 2 
Query:  290 PKGLKPLHGPSGWPLIGNLFTIKE----------PLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNS--GILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEE----SCGKV--ISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVS-DKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEV----WKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            PK   P  GP+ +P++G+   + +           +  F  +    YG  +   +G   +V+  +N  +S+ +  + I   GR   I  +    NS  G+L TDGE W  QR F L+ LK+FGF +    +I+ +E   LL+++++    S GK   I    L     +N +  +    R+E  +P    L      + +N + +  +   +P+L     IA     ++G  +    ++      IE H+  +   +E  D +D +LR + E ++EK +   F+D  L+ +  ++F+AG ETT+ +L +  + +    EIQ++  +EI  ++G ERIP  S D+  LPY +A+  E  R+  +    +PHR + ++ ++G  IPK++++     AC R   +    +  P  F P+ +L D   G +K    +   PF  G+ +C+G+ L R   F+F T+++Q FK+
Sbjct:   24 PKRFPP--GPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNEDI--DGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLR---FIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM---FSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVI----ACFRGMLINPVDFPDPESFNPDRYLFD---GHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp303a1 (gene:FBgn0001992 transcript:FBtr0080828)

HSP 1 Score: 174.481 bits (441), Expect = 9.596e-47
Identity = 125/468 (26.71%), Postives = 228/468 (48.72%), Query Frame = 2 
Query:  290 PKGLKPLHGPSGWPLIGNLFTIKE----------PLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNS--GILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEE----SCGKV--ISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVS-DKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEV----WKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            PK   P  GP+ +P++G+   + +           +  F  +    YG  +   +G   +V+  +N  +S+ +  + I   GR   I  +    NS  G+L TDGE W  QR F L+ LK+FGF +    +I+ +E   LL+++++    S GK   I    L     +N +  +    R+E  +P    L      + +N + +  +   +P+L     IA     ++G  +    ++      IE H+  +   +E  D +D +LR + E ++EK +   F+D  L+ +  ++F+AG ETT+ +L +  + +    EIQ++  +EI  ++G ERIP  S D+  LPY +A+  E  R+  +    +PHR + ++ ++G  IPK++++     AC R   +    +  P  F P+ +L D   G +K    +   PF  G+ +C+G+ L R   F+F T+++Q FK+
Sbjct:   24 PKRFPP--GPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYG-FYGLKIGKDKVVIAYTNDAISEMMTNEDI--DGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLR---FIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM---FSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVI----ACFRGMLINPVDFPDPESFNPDRYLFD---GHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Match: Cyp305a1 (gene:FBgn0036910 transcript:FBtr0074925)

HSP 1 Score: 166.392 bits (420), Expect = 7.991e-44
Identity = 130/484 (26.86%), Postives = 235/484 (48.55%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWS-----FLYKQTFK--YGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAK--TLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFER-DTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRF--NVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEI---VNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDE-LVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
             ++ +   L  + +  L++    PK   P  GP   P +GN    ++   +      L+++  K     L    +G R+ VV++    + K ++ + + F GR  N   +  T+    GI  TDG+ W   R FA+K +++ G+G+ +    I  E   LL ++E +  + I   +   +  +NV+  L    R  R +    + L   + R ++  +    +L  +P L     +A     ++  +Q   E++  F   IEEH+++   +      D I  +L+E  +  +    + TF + QLV  I + F+AG +TTS T+  A++++A   ++Q+K+  ++   V    ++  P++S +++  Y  A + E+ R   + P++ P R L  +++ G  IPKN+ I  +L + H D E WK P EF PE F+ D +    K    DE  +PF +G+R+CLG+ALAR   F F   I+Q F V
Sbjct:    3 ALIFLCAILIGFVIYSLISSARRPKNFPP--GPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRSDLVGLKLG-REYVVVALGHEMVKEVQLQEV-FEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRH---VAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKD-RSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFI-DSAGKCFK----DEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSV 473
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2y3 (cytochrome P450, family 2, subfamily Y, polypeptide 3 [Source:ZFIN;Acc:ZDB-GENE-050522-490])

HSP 1 Score: 257.684 bits (657), Expect = 4.899e-77
Identity = 156/439 (35.54%), Postives = 246/439 (56.04%), Query Frame = 2 
Query:  335 IGNLFTIKE--PLWSFL-YKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGRE----QEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFL----REKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            IGNL T+ +  P  SF+ +++T  YG +    +G + +VV+   + + +AL ++   F+ R        +V   G+  ++GE W   R F L  L+DFG G++R  + I  E  +LLK  EE+  K +     F +   NVI  L    RF+ +  NF  L   + ++ +         L  P  + Y    +++  FS R     ++ E +    R  ++EH++R +  ++  DFID FL    +EK +LD E      F    L+  +  LFVAG ETTSTTL +A++L+ K+ +IQ+++ +EI  +IG  RIP + D+KSLP+T AV+ E+ R   +VPLSLPH  +++    G  IPK+++I P L++  RD   W+ P+ F PEHFL  +SNG+ K +P    +PFS GKR C+GE+LARME F+F  S++Q+F
Sbjct:   40 IGNLLTLDKSAPFKSFMKWRKT--YGSVMTVHLGPQRMVVLVGYETVKEALVDQADDFAPRAPIPFMNRIVKGYGLAISNGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLR--------FLSSPWGQLYNIFPQVMESFSSRHHAILKDVENIRTFIRNKVKEHEQRLDF-SDPSDFIDCFLIRLTQEKDKLDTE------FHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGHWETPWTFNPEHFL--DSNGNFKKNP--AFMPFSAGKRVCVGESLARMEIFLFIVSLLQKF 457
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2y3 (cytochrome P450, family 2, subfamily Y, polypeptide 3 [Source:ZFIN;Acc:ZDB-GENE-050522-490])

HSP 1 Score: 256.529 bits (654), Expect = 1.487e-76
Identity = 155/439 (35.31%), Postives = 245/439 (55.81%), Query Frame = 2 
Query:  335 IGNLFTIKE--PLWSFL-YKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGRE----QEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFL----REKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            IGNL T+ +  P  SF+ +++T  YG +    +G + +VV+   + + +AL ++   F+ R        +V   G+  ++GE W   R F L  L+DFG G++R  + I  E  +LLK  EE+  K +     F +   NVI  L    RF+ +  NF  L   + ++ +         L  P  + Y    +++  FS R     ++ E +    R  ++EH++R +  ++  DFID FL    +EK +LD E      F    L+  +  LFVAG ETTSTTL +A++L+ K+ +IQ+++ +EI  +IG  RIP + D+KSLP+T AV+ E+ R   +VPLSLPH  +++    G  IPK+++I P L++  RD   W+ P+ F PEHFL  +SNG+ K +P    +PFS GKR C+GE+LA ME F+F  S++Q+F
Sbjct:   40 IGNLLTLDKSAPFKSFMKWRKT--YGSVMTVHLGPQRMVVLVGYETVKEALVDQADDFAPRAPIPFMNRIVKGYGLAISNGERWRQLRRFTLTTLRDFGMGRKRMEQWIQEESRYLLKSFEETKSKPVDPTFFFSRTVSNVICSLVFGQRFDYEDKNFLQLLQIISKLLR--------FLSSPWGQLYNIFPQVMESFSSRHHAILKDVENIRTFIRNKVKEHEQRLDF-SDPSDFIDCFLIRLTQEKDKLDTE------FHKDNLMATVLNLFVAGTETTSTTLRYALMLLIKHPQIQEQMQREIDRVIGQNRIPTMEDRKSLPFTDAVIHEVQRYMDIVPLSLPHYAMKDITFRGYKIPKDTVIIPMLHSVLRDEGQWETPWTFNPEHFL--DSNGNFKKNP--AFMPFSAGKRSCVGESLASMELFLFTVSLLQKF 457
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2k21 (cytochrome P450, family 2, subfamily k, polypeptide 21 [Source:ZFIN;Acc:ZDB-GENE-091113-17])

HSP 1 Score: 244.588 bits (623), Expect = 7.108e-72
Identity = 157/452 (34.73%), Postives = 232/452 (51.33%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILL----MYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVD 1651
            GP   PL+GNL T+    P  +F +K +  YG +F+  +G    VV+   K + +AL      F  R        +    GILF++GE W   R FAL  L+DFG GK+ S E I  E   L  E ++  GK             N+I+ +    RFE   P F   T  V+R  +N     +I +    ++P L  + +  ++++      Q   +M     A++E         N+   F+D FL  K   +     +  F +  L+  +  LF+AG +TT TTL W ++LMAK   IQD+V +EI  +IG  R P V D+K LPYT AV+ EI R+ ++VPLSLPHR   +   NG FI K + + P L +  +D   W++P  FYPEHFL ++     ++   D  +PFS G+R CLGE+LARME F+FFTS++Q ++      +S D
Sbjct:   47 GPKPLPLVGNLLTLDLTRPFDTF-FKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQF---TEMVDRANENVRVGGSISMWLYDIFPWLGPFLKNKRIIVE--NIIQSRVQMTKLITALLETLNP-----NDPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKG----QFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSED 482
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: cyp2n13 (cytochrome P450, family 2, subfamily N, polypeptide 13 [Source:ZFIN;Acc:ZDB-GENE-041001-158])

HSP 1 Score: 242.662 bits (618), Expect = 2.789e-71
Identity = 153/469 (32.62%), Postives = 243/469 (51.81%), Query Frame = 2 
Query:  317 PSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKN-IIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQE----FEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTM-GTDGTIRAP 1699
            P   PL+GN+F +  KEP   +L K    Y  +F   +G    V I+  K++ +AL  +   F  R  + ++A+    N+G+ F++GE W  QR FAL  L++FG GK+     I  E  FLL+EI+E  G       L      N+I ++    RF+     FK +   + +  Q +  +        I E +P I K L    G   +    ++ + +    +I +HK + +  +E  D+ID FL E  E  +E+V  + F +  LV  + +LF+AG E+TS TL W +I +    ++Q+KV +EI  +IG+ R P+++DK ++PYT+AV+ EI R   V+PL+       ++ +   FIPK + + P L++   D   W+ P++F P HFL  E     K+   D  +PFS GKR CLGE +AR+E F+FF S+ ++F+       S     K+ M G  G  R P
Sbjct:   41 PFSVPLLGNIFNVDSKEPHL-YLTKLGHAYNNIFSLRLGSDKTVFITGYKMVKEALVTQAENFVDRPNSPVLARVYSGNAGLFFSNGEMWKKQRRFALSTLRNFGLGKKTMELAICEESRFLLEEIDEQKGAAFDPTILLYNAVSNIICQMVFGQRFDYADHQFKTMLKYISKSIQLEGSVWG-----QIYEAFPAIMKHL---PGPHNDIFSNYDLLKSFVHEVIVKHKAKLD-PSEPRDYIDTFLIEMKEKPHERV--NGFEEPNLVACVLDLFLAGTESTSNTLCWGLIYLIMYPDVQEKVQEEIDRVIGNSREPSIADKPNMPYTEAVIHEIMRFGDVIPLNGLRVAARDTTLGECFIPKGTTVLPILHSVLFDENEWETPYKFNPGHFLDKEG----KFVRRDAFMPFSAGKRVCLGEQIARIELFLFFVSLFRKFR------FSATEGEKLNMDGVIGITRTP 487
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Match: CU179648.2 (cytochrome P450 2F2-like [Source:NCBI gene;Acc:100148115])

HSP 1 Score: 241.891 bits (616), Expect = 4.598e-71
Identity = 158/484 (32.64%), Postives = 246/484 (50.83%), Query Frame = 2 
Query:  257 FLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTD-GEWWATQRSFALKVLKDFGFGK----QRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMY---PILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGT 1678
            FL  L  R   PK   P  GP+  P+ GNL  +    PL  F  K    YG ++   +G +  VV++  K++ +AL  +   FSGR  N++   +    G++  D GE W   R FAL  L++FG GK    QR  E + H C  L    EES GK I  + L+ +   N+IA +    RF      F+ L  +VE +   K  I    ++Y   P+L  +P      L F    Q FE++  H   ++EEHK    V  E  D ID +L E   ++N+     +F + Q+V ++F+LF+AG ETTS TL    + +     IQ++  +EI  ++G+       D+ ++ + QAV+ E  RV  + PLS+ H    ++++ G  IPK +II P L +  R+   WK P EF P++FL ++     ++   D  +PFS G R CLGE LARME F+   ++++RF++ + K+     +  +  GT
Sbjct:   13 FLLYLQLRIRRPKNFPP--GPAPVPIFGNLLQLNRISPLKDF-DKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLL----EESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDL--TKITIGPWAMLYEIAPVLRIFP------LPFQKAFQYFEQITKHVLKVVEEHKTS-RVAGEPRDLIDCYLEE---MENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREESQWKFPHEFNPQNFLNEKG----EFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGT 473
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: cat1 (calcium transporter 1 [Source:Xenbase;Acc:XB-GENE-6453137])

HSP 1 Score: 285.804 bits (730), Expect = 1.883e-87
Identity = 163/438 (37.21%), Postives = 238/438 (54.34%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            GP GWPL+GN+F+I  K+P  +++ + + KYGP+F   MG + +V++   + +  AL      F GR    + K L    GI F++GE W   R F +  LKDFG GK    E I+HEC++L++      GK     ++      N+IA +    R E + P F + +  N E V    + +VTI  M+P L   P   K +      E+  +E++A  R    EH+K  ++ ++   FID+FL  + E          F +  LVR++  +F AG ETTST+L WA++LM K  +IQ+KVH EI  +IGS   P  S +  +P+T AV+ EI R   +VPLS+PH    +    G FIPK + I P L +  +D   +  P EF P HFL  E N    +   +  +PFS G+R C GE LARME FIFFTS++Q+F
Sbjct:   35 GPKGWPLVGNVFSIDLKKPQRTYI-ELSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRASIPVNKNLEKGLGITFSNGENWKAMRRFTITTLKDFGMGKSTIEETIAHECSYLVQYFASFKGKPFDNSTILSTSVANIIAPILFGHRMEYEDPVFLRLVNLNSEYVKLLGSPMVTIYNMFPALGFLPGCHKTI------EKNLKELYAFVRRTFVEHQKHLDIHDQ-RSFIDVFLARQKEEAKHPETKSYFHNENLVRLVRNVFSAGMETTSTSLRWALLLMIKYPDIQEKVHDEISRVIGSAH-PTYSHRTQMPFTNAVIHEILRFADIVPLSVPHETTRDVHFKGYFIPKGTYIIPLLSSVLKDKTQFDAPEEFNPNHFLDSEGN----FLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKF 459
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: parp11 (poly(ADP-ribose) polymerase family member 11 [Source:Xenbase;Acc:XB-GENE-979660])

HSP 1 Score: 281.182 bits (718), Expect = 1.170e-85
Identity = 161/442 (36.43%), Postives = 247/442 (55.88%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFL-REKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            GP GWPL+GN+F+I  K+P  +++ + + KYGP+F   MG + +V++   + +  AL      F GR    + K L    G++F++GE W   R F +  LKDFG GK    E I+HEC++L++      GK     ++      N+I  + +  R E + P F + +  N E V    + +VTI  M+P L   P   K +      ++  +E++A  +    E++K+F++ ++   FID+FL R+K E  + +  ++ F +  LVR++  LF AG ETTST L WA++LM K  +IQ+KVH EI  +IGS   P  S +  +P+T AV+ EI R   +VPLS+PH    +    G FIPK + I P L +  +D   +  P +F P HFL  E N    +   +  +PFS G+R C GE LARME FIFFTS++Q+F  +
Sbjct:   35 GPKGWPLVGNVFSIDLKKPQRTYI-ELSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRAYIPVTKDLEKGLGMIFSNGENWKAMRRFTITTLKDFGMGKSTIEETIAHECSYLVQYFASFKGKPFDNSTILITSVANIIVAILLGHRMEYEDPVFLRLVNLNSEYVKLLGSPMVTIYNMFPALGFLPGCHKTV------KKNLKELYAFLKRTFVEYQKKFDIHDQ-RSFIDVFLARQKEEAKHPETYSY-FHNENLVRLVRNLFSAGMETTSTALRWALLLMIKYPDIQEKVHDEISRVIGSVH-PTYSHRTQMPFTNAVIHEILRFADIVPLSVPHETTRDVHFKGYFIPKGTYIIPLLTSVLKDKTQFDAPEQFNPNHFLDSEGN----FLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKFSFR 462
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: tuba1c (tubulin alpha 1c [Source:Xenbase;Acc:XB-GENE-493848])

HSP 1 Score: 277.715 bits (709), Expect = 2.287e-84
Identity = 161/441 (36.51%), Postives = 236/441 (53.51%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            GP GW L+GN+F+I  K+P  +++ + + KYGP+F   MG + +V++   + +  AL      F GR    + K L    GI F++GE W   R F +  LKDFG GK    E I+HEC++L++      GK     ++      N+I  + +  R E + P F + L  N E V    + +VTI  M+P L   P   K +      E+  +E++A  R    EH+K  ++ ++   FID FL  + E          F +  LVR++  +F AG ETTST L WA++LM K  +IQ+KVH EI  +IGS   P  S +  +P+T AV+ EI R   +VPL++PH    +    G FIPK + I P L +  +D   +  P EF P HFL  E N    +   +  +PFS G+R C GE LARME FIFFTS++Q+F  +
Sbjct:   35 GPKGWSLVGNVFSIDLKKPQRTYI-ELSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRAYIPVNKDLEKGLGITFSNGENWKAMRRFTITTLKDFGMGKSTIEEKITHECSYLVQYFASFKGKPFDNSTILITSVANIIVAILLGHRMEYEDPVFLRLLNLNSEYVKLLGSPMVTIYNMFPALGFLPGCHKTI------ERNMKELYAFVRRTFVEHQKNLDIHDQ-RSFIDAFLARQKEEAKHPETKSYFHNENLVRLVRNVFSAGVETTSTALRWALLLMIKYPDIQEKVHDEISRVIGSAH-PTYSHRTQMPFTNAVIHEILRFADIVPLNVPHETTRDVHFKGYFIPKGTYIIPLLSSVLKDKTQFDAPEEFNPNHFLDSEGN----FLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKFSFR 462
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: ENSXETT00000021944.1 (cytochrome P450 2K1-like [Source:NCBI gene;Acc:100495200])

HSP 1 Score: 277.715 bits (709), Expect = 2.410e-84
Identity = 160/442 (36.20%), Postives = 241/442 (54.52%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFL-REKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            GP GWPL+GN F+I  K+P  +++ + + KYGP+F   MG + +V++   + +  AL      F GR    +   L    G++F++GE W   R F +  LKDFG GK    E I+HEC++L++      GK     ++      N+I  + +  R + + P F + +  N E V    + +VTI  M+P L   P   K +      E+  +E++A  R    EH+K  ++ ++   FID FL R+K E  + +  ++ F +  LVR++  LF AG ETTST L WA++LM K  +IQ+KVH EI  +IGS   P  S +  +P+T AV+ EI R   ++PL +PH    +    G FIPK + I P L +  +D   +  P EF P HFL  E N    +   +  +PFS G+R C GE LARME FIFFTS++Q+F  +
Sbjct:   35 GPKGWPLVGNGFSIDLKKPQRTYI-ELSKKYGPVFSVQMGRKKMVILVGYETVKDALVTHAEEFGGRASIPVNNNLEKGLGMIFSNGENWKAMRRFTITTLKDFGMGKSTIEETIAHECSYLVQYFASFKGKPFDNSTILITSVANIIVAILLGHRMDYEDPVFLRLVNLNSEYVKLLGSPMVTIYNMFPALGFLPGCHKTI------EKNIKELYAFVRRTFVEHQKHLDIHDQ-RSFIDAFLARQKEEAKHPETYSY-FHNENLVRLVRNLFSAGMETTSTALRWALLLMIKYPDIQEKVHDEISRVIGSAH-PTYSHRTQMPFTNAVIHEILRFADILPLGVPHETTRDVHFKGYFIPKGTYIIPLLSSVLKDKTQFDAPEEFNPNHFLDSEGN----FLKKEAFMPFSAGRRACPGEILARMELFIFFTSLLQKFSFR 462
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Match: cyp2f1 (cytochrome P450 2K1 [Source:NCBI gene;Acc:100490476])

HSP 1 Score: 248.44 bits (633), Expect = 2.417e-73
Identity = 155/471 (32.91%), Postives = 241/471 (51.17%), Query Frame = 2 
Query:  314 GPSGWPLIGNL--FTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYP-ILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDV 1714
            GP   PLIGNL    +K+P  +F+ + + KYGP+F   +G    +V+     +  AL   G  FSGR K  +   +    G++F DGE W   R FAL  L+DFG G++   + I  E   L++  +    K      +      N+I  + +N RFE   P   K + +  E V    + IV +   YP I+   P   K +       + F+++    +    + + + +V N+  D ID FL ++ E  +       F D  L  ++ +LF AG ETTSTTL W +++M K  +IQ KV  EI  +IGS   P +  +K +PYT AV+ EI R  ++VP+ LPH + E+    G F+PK + + P L +  +D + +++P EFYPEHFL  + N    +   +  +PFS+GKR C+GE LA+ME F+FFT ++Q F  +    + V    ++T G D     PL   +
Sbjct:   33 GPKPLPLIGNLHMMNMKKPHLTFM-EFSKKYGPVFSIQLGLNKAIVLCGADAVKDALINHGDEFSGRPKIPVFDQISKGYGVVFADGENWKVMRRFALSTLRDFGMGRKTIEDTIVEESGCLVETFKSHEAKPFDNTLILNAAVANIIVHILLNHRFEYQDPTLIKLIKSVSENVKIAGSPIVMLYNTYPSIMGWIPGSHKTVF------ENFQKLSNFLKETFTKRRDQLDV-NDQRDLIDAFLVKQQEEKSSS--KKFFHDENLKVLLGDLFAAGMETTSTTLRWGILMMMKYPDIQKKVQDEIDRVIGSAE-PRLEHRKQIPYTDAVIHEIQRFANLVPIVLPHSITEDVTFRGYFLPKGTQVIPLLISVMQDKDYFQKPEEFYPEHFLDSKGN----FVKNEAFLPFSVGKRSCVGETLAKMELFLFFTKLLQNFTFQPPPGVEV----QLTCG-DALTSIPLDHQI 483
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2j6 (cytochrome P450, family 2, subfamily j, polypeptide 6 [Source:MGI Symbol;Acc:MGI:1270148])

HSP 1 Score: 250.366 bits (638), Expect = 3.679e-74
Identity = 156/470 (33.19%), Postives = 255/470 (54.26%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILL-MYPILEEY-PRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            V  V  L L  YF ++       PK   P  GP G P +GN+F +   +P  S +     KYG +F   +G    VVI+   ++ +AL +       R  +++ + + + +G++F+ G+ W  QR FAL  L++FG GK+   E +  E + L++ I E  GK  +          N+I  +    RF+     F+ +   ++ V   +  +++ L  ++P + +Y P   + + R       +E++      +I++H+K +N  +E  DFID FL+E  +   +     +F +  L+    +LF AG ETTSTTL WA++ MA   E+Q+KV  EI  +IG +R   ++D++S+PYT AV+ E+ R+ +++PL++P  +  ++ +NG  +PK +++  NL A HRD + W  P  F PEHFL    NG  K    +  +PFS+GKR CLGE LAR E FIFFTS+MQ+F
Sbjct:   23 VAAVTFLLLADYFKNRR------PKNYPP--GPWGLPFVGNIFQLDFGQPHLS-IQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFR------NWEKLKLFVSCMIDDHRKDWN-PDEPRDFIDAFLKEMTKYPEKTT---SFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFL---ENGQFKKR--ESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF 468
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2b19 (cytochrome P450, family 2, subfamily b, polypeptide 19 [Source:MGI Symbol;Acc:MGI:107303])

HSP 1 Score: 245.743 bits (626), Expect = 1.710e-72
Identity = 154/477 (32.29%), Postives = 249/477 (52.20%), Query Frame = 2 
Query:  215 FEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQE----FEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHT-FTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            F V++++AL           ++P       P  GP   P +GNL  +  +  L SF+  Q  KYG +F   +G R +V++     + +AL  +   FSGR    +   +V   G++F+ GE W T R F+L  ++DFG GK+   E I  E   L++E+++  G  ++    F     N+I  +    RF+     F  L   +      + F +   L   + E +  I K    F G  ++     +E+  +    +E+H+   +  +   DFID +L     ++ EK  +HT F    LV  +  LF AG ETTSTTL ++ ++M K   + +KV KEI  +IGS R+P + D+  +PYT AV+ EI R T + P+ LPH++ +++   G  IPKN+ ++P L +   D   +++P  F PEHFL  ++NG++K +  +  +PFS GKR CLGE +AR E F+FFT+I+Q F +
Sbjct:    3 FSVLLLLALTTGFLIFLVSQSQPKTHGHFPP--GPRPLPFLGNLLQMDRRGLLSSFIQLQE-KYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLI-----YQTFSLMSSLSSQVFELFSAILKY---FPGAHRQISKNLQEILDYIGHSVEKHRATLD-PSAPRDFIDTYL---LRMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFL--DANGALKTN--EAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSL 460
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2a12 (cytochrome P450, family 2, subfamily a, polypeptide 12 [Source:MGI Symbol;Acc:MGI:105055])

HSP 1 Score: 244.202 bits (622), Expect = 5.836e-72
Identity = 147/447 (32.89%), Postives = 235/447 (52.57%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI-KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEF-EEMHAHFRAIIEEHKKRFNV--ENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEI 1642
            GP   P IGN   + ++ ++S + +    YGP+F   +G R +VV+     + +AL +    FSGR +     TL    G+ F++GE     R F++  L+DFG GK+   E I  E   L+K ++ +CG  I       K   NVI+ +    RF  +   F  L   ++ + Q   F  +     P  + Y     ++    G +Q+  ++ H     +I++ K+  +    N   DFID FL     +  EK +N  F    LV     LF AG ET S+TL +  +L+ K+ +++ KVH+EI  +IG  R P   D   +PYTQAV++EI R ++  PL +P R+ +++   G F+PK + +FP L +   D + +  P +F P+HFL D+  G +K  P    +PFS GKR CLG++LA+ME F+FFT+I+Q F+ KF +++
Sbjct:   35 GPIPLPFIGNYLQLNRKDVYSSITQLQEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKGYGVAFSNGERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCLIKMLQGTCGAPIDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSL---LQMMGQVNKFAAS-----PTGQLYDMFHSVMKYLPGPQQQIIKDSHKLEDFMIQKVKQNQSTLDPNSPRDFIDSFL---IHMQKEKYVNSEFHMKNLVMTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDK--GQLKKIP--AFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKFPRKL 466
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2f2 (cytochrome P450, family 2, subfamily f, polypeptide 2 [Source:MGI Symbol;Acc:MGI:88608])

HSP 1 Score: 243.432 bits (620), Expect = 1.233e-71
Identity = 154/453 (34.00%), Postives = 238/453 (52.54%), Query Frame = 2 
Query:  287 IPKGLKPLHGPSGWPLIGNLFTIK-EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF----KFLTANVERVAQNKNFIVTILLMYP-ILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            +P G KPL      P++GNL  ++ + L + L K + +YG +F   +G R ++V+S  + + +AL +KG  FSGR    +       +GI F+DGE W   R F++++L++FG GK+   E I  E +FLL+ + +  GK      +  +   N+I  +    RF+ D         F+  N + ++     +  I   +P +L+  P   K L R       F  M       + EH+   +  N   DFID FL  K   + +  L+H   D  L+     L   G ET  TTL  A +++ K  ++Q +V +EI  ++G  R+P + D+ S+PYT AV+ E+ R   V+P++LPHR+  ++   G  IPK + +   L   H D++ +K P EF PEHFL D  N S K SP    +PFS G+R CLGE LARME FI+FTSI+Q F ++
Sbjct:   30 LPPGPKPL------PILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNI---FPSVLDWIPGPHKRLFR------NFGGMKDLIARSVREHQDSLD-PNSPRDFIDCFL-TKMAQEKQDPLSHFNMD-TLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDD--NHSFKKSP--AFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQ 460
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Match: Cyp2j12 (cytochrome P450, family 2, subfamily j, polypeptide 12 [Source:MGI Symbol;Acc:MGI:3717097])

HSP 1 Score: 242.662 bits (618), Expect = 3.517e-71
Identity = 152/469 (32.41%), Postives = 239/469 (50.96%), Query Frame = 2 
Query:  230 VIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQ-TFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEY-PRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
             + LA   + L     +   PK   P  GP   P +GNLF +       + +Q   KYG L     G    V+I+   ++ +        F  R    I K + +N+G++ ++G+ W  QR FAL  LK+FG GK+   + I  E   L++ I E  G+             N+I   A   RFE +  +F + L    E      + +  +  ++P + +Y P   + +LR       +E++      ++E H+K +N  +E  DFID FL E  +  ++     +F +  L+    +LF AG ETT+ TL WA++ +  N E+Q+KVH EI  +IG  R P+  D+ S+PYT AV+ E+ R+ +++P+++P  +  +S + G  +PK +++  NL A HRD + W  P  F PEHFL    NG  K    +  +PFS+GKR C GE LAR E FIFFT++MQ+F  K
Sbjct:   20 TLVLAAVTFMLLAHYLKTQRPKNYPP--GPWRLPFVGNLFQLDLEQPHVVIQQFVKKYGNLTSLDFGNIPSVIITGLPLIKEVFTNMEQNFLNRPITPIRKRVFNNNGLIISNGQTWKEQRRFALMTLKNFGLGKKSLEQRIQKEADCLVEAIGEEKGQPFDPHFKINSAVSNIICTFAFGERFEYEDSHFHELLRLLDEATCLEASMMCQLYNVFPSIIQYVPGSHQTVLR------NWEKLKLFIYQMMESHRKDWN-PDEPRDFIDAFLTEMSKYGDKTTT--SFNEENLINSTLDLFFAGSETTTNTLRWALLYITTNPEVQEKVHSEIDRVIGHGRQPSTDDRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHFL---ENGQFKKR--ESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTFK 472
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BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|P00178|CP2B4_RABIT (Cytochrome P450 2B4 OS=Oryctolagus cuniculus OX=9986 GN=CYP2B4 PE=1 SV=1)

HSP 1 Score: 253.062 bits (645), Expect = 2.387e-74
Identity = 149/443 (33.63%), Postives = 240/443 (54.18%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYP-ILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFL--REKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            GPS  P++GNL  +  K  L SFL  +  KYG +F   +G R +VV+     + +AL ++   FSGR K  +   +    G++F +GE W   R F+L  ++DFG GK+   E I  E   L++E+ +S G ++    LF   T N+I  +    RF+   P F + L    +  +   +F   +  ++P  L+ +P   + + R        +E++      +E+H+   +  N   DFID++L   EK + D     +H      L+  +  LF AG ETTSTTL +  +LM K   + ++V KEI  +IGS R P + D+  +PYT AV+ EI R+  ++P  +PH + ++++  G  IPKN+ +FP L +   D   ++ P  F P HFL  ++NG++K +  +  +PFS+GKR CLGE +AR E F+FFT+I+Q F +
Sbjct:   33 GPSPLPVLGNLLQMDRKGLLRSFLRLRE-KYGDVFTVYLGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGERWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTLLFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFELFPGFLKHFPGTHRQIYR------NLQEINTFIGQSVEKHRATLDPSNP-RDFIDVYLLRMEKDKSDPSSEFHH----QNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPHVTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPHTVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFL--DANGALKRN--EGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSI 459
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|P12938|CP2D3_RAT (Cytochrome P450 2D3 OS=Rattus norvegicus OX=10116 GN=Cyp2d3 PE=2 SV=2)

HSP 1 Score: 252.292 bits (643), Expect = 4.948e-74
Identity = 147/441 (33.33%), Postives = 235/441 (53.29%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSF-LYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHN---SGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            GP  WP++GNL  +      + +YK   +YG +F   MG + +VVI+  K + + L   G   + R +  I + + +     G++    G  W  QR F++  L++FG GK+   + ++ E + L   +    G+ +   +L  K   NVIA L    RF+   P+F K L    E + +       +L M+P+L   P +A  +  F G ++ F  M      ++ EHKK ++ +    D  D FL E  +         +F D  L  V+ +LF AG  TTS TLTWA++LM  + ++Q +V +EI  +IG  R P ++D+  +P+T AV+ E+ R   +VP++LPH+   + E+ G  IPK + + PNL +  +D  VW++P  F+PEHFL  + N    +   +  +PFS G+R CLGE LARME F+FFT ++QRF
Sbjct:   39 GPVPWPVLGNLLQVDLCNMPYSMYKLQNRYGDVFSLQMGWKPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEWREQRRFSVSTLRNFGVGKKSLEQWVTDEASHLCDALTAEAGRPLDPYTLLNKAVCNVIASLIYARRFDYGDPDFIKVLKILKESMGEQTGLFPEVLNMFPVLLRIPGLADKV--FPG-QKTFLTM---VDNLVTEHKKTWDPDQPPRDLTDAFLAEIEKAKGNP--ESSFNDANLRLVVNDLFGAGMVTTSITLTWALLLMILHPDVQCRVQQEIDEVIGQVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGN----FVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRF 467
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|P24461|CP2G1_RABIT (Cytochrome P450 2G1 OS=Oryctolagus cuniculus OX=9986 GN=CYP2G1 PE=1 SV=1)

HSP 1 Score: 251.136 bits (640), Expect = 1.121e-73
Identity = 160/496 (32.26%), Postives = 258/496 (52.02%), Query Frame = 2 
Query:  206 FTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEF----EEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHT-FTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK-FEKEISVDAYAKMT 1669
            FTIF     +AL      +     R   P  L P  GP+  P +GNL  ++      SFL K   KYGP+F   MG R +V++  ++ + +AL ++   FSGR +    +      G+   +GE W   R F+L +L+DFG GK+   E I  E  +LL+E  ++ G  I       +   NVI+ +    RF+ +   F  L   +     N++FI    +  P  + Y   + ++    GR        EE+     A ++ ++   + +N   DFID FL + ++  N     HT F    LV     LF AG ET S+TL +  +L+ K+ E+Q K+++EI  +IG  RIP+V D+  +P+T AV+ EI R+T +VP+ +PH ++ ++   G  +PK + +FP L +  +D + +  P +FYP+HFL ++     ++   +  VPFS GKR CLGEA+ARME F++FTSI+Q F +      +++D   K++
Sbjct:    7 FTIF-----LALCFSCLLILIAWKRVQKPGRLPP--GPTPIPFLGNLLQVRTDATFQSFL-KLREKYGPVFTVYMGPRPVVILCGHEAVKEALVDRADEFSGRGELASVERNFQGHGVALANGERWRILRRFSLTILRDFGMGKRSIEERIQEEAGYLLEEFRKTKGAPIDPTFFLSRTVSNVISSVVFGSRFDYEDKQFLSLLRMI-----NESFIE---MSTPWAQLYDMYSGVMQYLPGRHNRIYYLIEELKDFIAARVKVNEASLDPQNP-RDFIDCFLIKMHQDKNNP---HTEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLIMKHPEVQTKIYEEINQVIGPHRIPSVDDRVKMPFTDAVIHEIQRLTDIVPMGVPHNVIRDTHFRGYLLPKGTDVFPLLGSVLKDPKYFCHPDDFYPQHFLDEQG----RFKKNEAFVPFSSGKRICLGEAMARMELFLYFTSILQNFSLHPLVPPVNIDITPKIS 478
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|O54750|CP2J6_MOUSE (Cytochrome P450 2J6 OS=Mus musculus OX=10090 GN=Cyp2j6 PE=2 SV=2)

HSP 1 Score: 250.366 bits (638), Expect = 2.573e-73
Identity = 156/470 (33.19%), Postives = 255/470 (54.26%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILL-MYPILEEY-PRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            V  V  L L  YF ++       PK   P  GP G P +GN+F +   +P  S +     KYG +F   +G    VVI+   ++ +AL +       R  +++ + + + +G++F+ G+ W  QR FAL  L++FG GK+   E +  E + L++ I E  GK  +          N+I  +    RF+     F+ +   ++ V   +  +++ L  ++P + +Y P   + + R       +E++      +I++H+K +N  +E  DFID FL+E  +   +     +F +  L+    +LF AG ETTSTTL WA++ MA   E+Q+KV  EI  +IG +R   ++D++S+PYT AV+ E+ R+ +++PL++P  +  ++ +NG  +PK +++  NL A HRD + W  P  F PEHFL    NG  K    +  +PFS+GKR CLGE LAR E FIFFTS+MQ+F
Sbjct:   23 VAAVTFLLLADYFKNRR------PKNYPP--GPWGLPFVGNIFQLDFGQPHLS-IQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFR------NWEKLKLFVSCMIDDHRKDWN-PDEPRDFIDAFLKEMTKYPEKTT---SFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFL---ENGQFKKR--ESFLPFSMGKRACLGEQLARSELFIFFTSLMQKF 468
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Match: sp|P10610|CP2G1_RAT (Cytochrome P450 2G1 OS=Rattus norvegicus OX=10116 GN=Cyp2g1 PE=2 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 1.004e-72
Identity = 149/452 (32.96%), Postives = 242/452 (53.54%), Query Frame = 2 
Query:  293 KGLKPLHGPSGWPLIGNLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEF----EEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHT-FTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            +G K   GP+  P +GNL  ++      SFL  Q  KYG +F    G R +V++  ++ + +AL ++   FSGR +    +      G+  ++GE W   R F+L VL++FG GK+   E I  E  +LL+E+ +  G  I       +   NVI  +    RF+ +   F+ L   +     N++F+   +   P  + Y     ++  F GR        EE+     + ++ ++  F+  N   DFID FL + Y+   +K   H+ F    LV     LF AG ET S+TL +  +L+ K  E++ K+H+EI  +IG+ R P V D+  +PYT AV+ EI R+T +VPL +PH ++ ++   G F+PK + ++P + +  +D + ++ P  FYP+HFL ++     ++   D  V FS GKR C+GEALARME F++FTSI+QRF ++
Sbjct:   29 RGGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQK-KYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMI-----NESFVEMSM---PWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNP-RDFIDCFLIKMYQ---DKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQG----RFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLR 463
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A4P8NYX5 (P450 2B-like protein OS=Dugesia japonica OX=6161 GN=p4502B PE=2 SV=1)

HSP 1 Score: 496.508 bits (1277), Expect = 2.627e-165
Identity = 234/481 (48.65%), Postives = 339/481 (70.48%), Query Frame = 2 
Query:  278 RPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVF 1720
            R SIPKGLK      G P++G +  IKEP+ ++L K + K+GP+F+  +G RD++++S+  I+ KAL + G  FSGRW+  +   + H+SGI+F DG+ W+TQRSF LKVL+DFG GK +S +++ +EC+FLL+E+E   GK+I    + P  T N+I+K  MN RFER+ P    +   +    + K+ I  + +M+P  +      +L++ F+ + +EF E+  +F+  I+EH K  +  +EGED +D FL ++ +L  + +   +F DWQL+R   ELF AGYETTSTTL W+ + M+K+ +IQ KVH EI+ IIG ER+P ++DKKS+ YTQAVMDEIFR++SV PL+L HR L ++ I+G FIPKN++IFPNLYACH D ++W++P  FYPEHFLT++ NG++KY+P DEL+ FSIGKRQCLGE+LARMEFFIFFTSI+QRF+VK  KE++   Y +  +G DG IR  + +D +F
Sbjct:   23 RNSIPKGLKETPIEYGLPILGIIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIF 503
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A2U8U473 (Cytochrome P450 2K1-like protein OS=Dugesia japonica OX=6161 GN=P450 PE=2 SV=1)

HSP 1 Score: 462.225 bits (1188), Expect = 6.044e-152
Identity = 220/501 (43.91%), Postives = 326/501 (65.07%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFE 1723
            ++ +  L +  Y  S++  R SIP GLK      GWP++G +  IK P+ ++L + + K+GP+F+  +G RD+V++ + + + KAL +    FSGRWK  +   + H+SGI+F DG  W+TQRSF LKVL+DFG GK  S +I+  EC FLL E++   G++I    + P  T N+I+K  MN RF+R  P  KF+   + + ++  + +  + LM+PI ++   I+K  L  + + Q F ++   F   IEEHK   +  +EG+D ID FL E+  L     +  +FTD QL+ + FE+F AGYETTSTTL W+M+ M++  +IQ KV++EI+N+IG ER+P ++DKKSL YTQAVMDEI R++SV PL + HR   ++ ++  FIPKNS++F N YACH D ++W +P EFYPEHFL    N  +KYSP +EL+PF IGKRQC+GE+LARME+FIFF SI+QR++V F + IS   + +   G +G IR     + +F+
Sbjct:    4 ILSIFGLFIIWYCFSRVFKRRSIPNGLKETPIEYGWPILGIIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIFK 504
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A267GWC9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026100g2 PE=3 SV=1)

HSP 1 Score: 291.967 bits (746), Expect = 2.385e-86
Identity = 178/523 (34.03%), Postives = 285/523 (54.49%), Query Frame = 2 
Query:  203 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPS-GW-PLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAK-TLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEES-CGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFK-----FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGRE---QEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFE--KEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            M T+  + ++    L +YFL        + K  KP   PS GW PL+G+L  +K+ L S +  + F   PL     G   + ++++ +   +A+ ++G  F GR   ++ K TL  + GI+ T+GE W   R F+LK L+DFGFG+Q   EII  E   L + I+ +  G+ +S   L      NVI +L    R   + P F      F +    R A++ N ++     Y   E++  +AKL+L    R    Q   ++    +  + +HK   ++++E  D+ID  L+ +  L+++++    F D +L   I +LFVAG +TTS TL W ++ M +N ++ +KV +EI   +G+ER+P + DK SL YT AV++E+ R+ ++VP+ + HR +E+S I G  IP +S++ PN+Y  HRD  V+  P +F PE +L  E     ++SP + +VPF  GKR CLGE+LARME F+FFT +MQR++   +  +  S+      T    G IRAP    +VF  R
Sbjct:    1 MLTLIAMGLITGAVLLLYFLC-------VKKAPKPNEPPSPGWMPLVGSLPYMKKNLASQML-EGFPNSPLVTLYYGLEPVYILNNFEAFDEAMVKQGQRFIGRPVRVLQKPTLGSDGGIVSTEGELWREYRRFSLKTLRDFGFGRQGGEEIILREAGELCEAIDSTPAGQALSTTDLLSPAVSNVICQLVFGARTATEDPRFPKLLDMFQSLTQRRAARHMNIMLGA--NYKYFEQFSFLAKLMLLRPERRRVIQLSRQLLQFCKEQVAKHKGDADMQSEPRDYIDAHLQHQTNLESDRI----FNDLRLAMAIRDLFVAGTDTTSNTLRWGILYMIENPDVAEKVFEEIRVNVGTERMPTMKDKGSLHYTVAVLEEVQRLGTLVPMGVAHRCVEDSVICGYRIPADSVVVPNIYGIHRDPRVFPEPEKFKPERYLDAEG----RFSPNESVVPFGSGKRACLGESLARMELFVFFTRLMQRYRFGLDPAERRSISEIKDNTENHGGGIRAPAEHKIVFTPR 505
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A1I8IP39 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig026100g1 PE=3 SV=1)

HSP 1 Score: 290.426 bits (742), Expect = 9.536e-86
Identity = 176/523 (33.65%), Postives = 285/523 (54.49%), Query Frame = 2 
Query:  203 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPS-GW-PLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAK-TLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEES-CGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFK-----FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGRE---QEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFE--KEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            M T+  + ++    L +YFL        + K  KP   PS GW PL+G+L  +K  L S +  ++F   PL     G   + ++++ +   +A+ ++G  F GR   ++ K TL  + GI+ T+GE W   R F+LK L+DFGFG+Q   EII  E   L + I+ +  G+ +S   L      NVI +L    R   + P F      F +    R A++ N ++     Y   E++  +AKL+L    R    Q   ++    +  + +HK   ++++E  D+ID  L+ +  L+++++    F D +L   I +LFVAG +TTS TL W ++ M +N ++ +KV +EI   +G+ER+P + DK SL YT AV++E+ R+ ++VP+ + HR +E+S I G  IP +S++ PN+Y  HRD  V+  P +F PE +L ++     ++SP + +VPF  GKR CLGE+LARME F+FFT +MQR++   +  +  S+           G IRAP    +VF  R
Sbjct:    1 MLTLIAMGLIAGAVLLLYFLC-------VKKAPKPNEPPSPGWMPLVGSLPYMKNNLASQML-ESFPNSPLVTLYYGLEPVYILNNFEAFDEAMVKQGQRFIGRPVRVLQKPTLGSDGGIVSTEGELWREYRRFSLKTLRDFGFGRQGGEEIILREAGELCEAIDSTPAGQALSTTDLLSPAVSNVICQLVFGARTATEDPRFPKLLDMFQSLTQRRAARHMNIMLGA--NYKYFEQFSFLAKLMLLRPERRRVIQLSRQLLQFCKEQVAKHKGDADMQSEPRDYIDAHLQHQTNLESDRI----FNDLRLAMAIRDLFVAGTDTTSNTLRWGILYMIENPDVAEKVFEEIRVNVGTERMPTMKDKGSLHYTVAVLEEVQRLGTLVPMGVAHRCVEDSVICGYRIPADSVVVPNIYGIHRDPRVFPEPEKFKPERYLDEDG----RFSPNESVVPFGSGKRACLGESLARMELFVFFTRLMQRYRFGLDPAERRSISEIKDNAENHGGGIRAPAEHKIVFTPR 505
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Match: A0A267H3D9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig009067g1 PE=3 SV=1)

HSP 1 Score: 288.115 bits (736), Expect = 5.331e-85
Identity = 176/523 (33.65%), Postives = 283/523 (54.11%), Query Frame = 2 
Query:  203 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPS-GW-PLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAK-TLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEES-CGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFK-----FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFE---EMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFE--KEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            M T+  + ++    L +YFL        + K  KP   PS GW PL+G+L  +K  L S +  + F   PL     G   + ++++ +   +A+ ++G  F GR   ++ K TL  + GI+ T+GE W   R F+LK L+DFGFG+Q   EII  E   L + I+ +  G+ +S   L      NVI +L    R   + P F      F +    R A++ N ++     Y   E++  +AKL+L    R +      ++    +  + +HK   ++++E  D+ID  L+ +  L+++++    F D +L   I +LFVAG +TTS TL W ++ M +N ++ +KV +EI   +G+ER+P + DK SL YT AV++E+ R+ ++VP+ + HR +E+S I G  IP +S++ PN+Y  HRD  V+  P +F PE +L  E     ++SP + +VPF  GKR CLGE+LARME F+FFT +MQR++   +  +  S+           G IRAP    +VF  R
Sbjct:    1 MLTLIAMGLIAGAVLLLYFLC-------VKKAPKPNEPPSPGWMPLVGSLPYMKNNLASQML-EGFPNSPLVTLYYGLEPVYILNNFEAFDEAMMKQGQRFIGRPVRVLQKPTLGSDGGIVSTEGELWREYRRFSLKTLRDFGFGRQGGEEIILREAGELCEAIDSTPAGQALSTTDLLSPAVSNVICQLVFGARTATEDPRFPKLLDMFQSLTQRRAARHMNIMLGA--NYKYFEQFGFLAKLILLRPERRRVIHLSRQLLQFCKEQVAKHKGDADMQSEPRDYIDAHLQHQTNLESDRI----FNDLRLAMAIRDLFVAGTDTTSNTLRWGILYMIENPDVAEKVFEEIRVNVGTERMPTMKDKGSLHYTVAVLEEVQRLGTLVPMGVAHRCVEDSVICGYRIPADSVVVPNIYGIHRDPRVFPEPEKFKPERYLEAEG----RFSPNESVVPFGSGKRACLGESLARMELFVFFTRLMQRYRFGLDPVERRSIGEIKDNAENHGGGIRAPAEHKIVFTPR 505
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000052034.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000046.1:5870600:5884237:1 gene:ENSAMXG00000018921.2 transcript:ENSAMXT00000052034.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 255.373 bits (651), Expect = 2.699e-76
Identity = 157/428 (36.68%), Postives = 223/428 (52.10%), Query Frame = 2 
Query:  374 FLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPI--LEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVD 1651
            FL  +T  YG +FK   G + +VV++  K + +AL      F  R    + K L    GILF++GE W   R FAL  L+DFG GK+ S E I  E  ++++E  +  GK             N+I+ +    RFE   P FK +   V R  +N    V I    PI     +P I   L      E+  E+       II   ++  + ++    FID FL  K   +     N  F D  L+  +  LFVAG +TT TTL W ++LMAKN  IQD+VH+EI  +IG  ++  V D+KSLPYT AV+ EI R  ++VP+SLPH    +   NG FI K + ++P L +  RD   W+ P  F P+HFL  +     +++  D  +PFS G+R CLGE+LARME F+FFTS++Q F+      +S D
Sbjct:   40 FLLAKT--YGSVFKVYFGPKKVVVLAGYKTVKQALVNHAEEFGEREIGKLFKNLSEEHGILFSNGENWREMRRFALTNLRDFGMGKRGSEEKIVEEIQYIVEEFGKFEGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDPQFKEM---VNRANEN----VRIGGSAPIRLYNVFPWIGPFLKSKRKLERNTEKNRKEINGIISSLQETLHPDDR-RGFIDSFLVRKQSDEKSGQKNSRFNDKNLLSTVLNLFVAGTDTTGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQVV-VEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPQTFNPDHFLDKQG----RFAKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFRFTPPPGVSKD 452
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000019491.2 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000046.1:5874953:5884237:1 gene:ENSAMXG00000018921.2 transcript:ENSAMXT00000019491.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 254.603 bits (649), Expect = 4.167e-76
Identity = 154/420 (36.67%), Postives = 219/420 (52.14%), Query Frame = 2 
Query:  398 YGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPI--LEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVD 1651
            YG +FK   G + +VV++  K + +AL      F  R    + K L    GILF++GE W   R FAL  L+DFG GK+ S E I  E  ++++E  +  GK             N+I+ +    RFE   P FK +   V R  +N    V I    PI     +P I   L      E+  E+       II   ++  + ++    FID FL  K   +     N  F D  L+  +  LFVAG +TT TTL W ++LMAKN  IQD+VH+EI  +IG  ++  V D+KSLPYT AV+ EI R  ++VP+SLPH    +   NG FI K + ++P L +  RD   W+ P  F P+HFL  +     +++  D  +PFS G+R CLGE+LARME F+FFTS++Q F+      +S D
Sbjct:   44 YGSVFKVYFGPKKVVVLAGYKTVKQALVNHAEEFGEREIGKLFKNLSEEHGILFSNGENWREMRRFALTNLRDFGMGKRGSEEKIVEEIQYIVEEFGKFEGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDPQFKEM---VNRANEN----VRIGGSAPIRLYNVFPWIGPFLKSKRKLERNTEKNRKEINGIISSLQETLHPDDR-RGFIDSFLVRKQSDEKSGQKNSRFNDKNLLSTVLNLFVAGTDTTGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQVV-VEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPQTFNPDHFLDKQG----RFAKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFRFTPPPGVSKD 450
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: cyp2n13 (cytochrome P450 2J6-like [Source:NCBI gene;Acc:103035066])

HSP 1 Score: 253.062 bits (645), Expect = 2.558e-75
Identity = 153/442 (34.62%), Postives = 231/442 (52.26%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWS-FLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFT-DGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQ----EFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFK 1621
            GP   P +GN+  I  P    +L K    Y  +F   +G + +++++  K++ +AL  +   F  R  + +A+ +   +G LFT +G  W  QR FAL  L++FG GK+     I  E  FLL E++   G+      LF     N+I +L    R++    +F+ +          +  I   L      E +P I K L    GR       +E +    +  +++HK   +  N   D++D FL EK   +N       F+D  LVR   +LF+AG ETT+T+L WA+I +AKN EIQDKV +EI  +IG  R P ++DK ++PYT+AV+ EI R   +VPLS P    +++ + G  IPK + I P L++   D + W+ P  F P+HFL  E     K+   D  + FS GKR CLGE LARME F+FFT + Q+F+
Sbjct:   40 GPLALPFLGNILDIASPQPHIYLTKLGKAYNNIFSMRIGQQKMILLTGYKMVKEALVNQTDNFVDRPYSPLAERIYSGNGGLFTSNGNLWKKQRRFALSTLRNFGLGKKTMELAICEESHFLLDEMDRHKGQAFDPSGLFNNAVSNIICQLVFGQRYDYADYDFQQMLKYTSEAIHLEGSIWGRLY-----ESFPNIMKHL---PGRHNVIFSNYEHISEFIKKNLDKHKANLDPSNP-RDYMDSFLIEK---ENSHDPADGFSDKNLVRCTLDLFLAGTETTTTSLGWALIYLAKNPEIQDKVQEEIDRVIGQSRQPGMADKPNMPYTEAVIHEILRRGDIVPLSGPRVAAKDTTLGGYAIPKGTTIMPILHSVLFDEDEWETPNSFNPQHFLDKEG----KFVRRDAFLAFSAGKRVCLGEQLARMELFLFFTCLFQKFR 465
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000019474.2 (cytochrome P450 2K1-like [Source:NCBI gene;Acc:103034280])

HSP 1 Score: 246.128 bits (627), Expect = 1.262e-72
Identity = 150/411 (36.50%), Postives = 219/411 (53.28%), Query Frame = 2 
Query:  398 YGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANV-ERVAQNKNFIVTILLMYPILEEYPR-IAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMF-LREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFK 1621
            YG +FK   G + +VV++  K + +AL      F  R  + + K      GILF++GE W   R FAL  L+DFG GK+ S E I  E  +L +  E   GK             N+I+ +    RFE   P FK +     E V    +  V +  M+P    + R + KL +         E+     R +++  ++  N E E   F+D F LR++ +  NEK     F +  L+  +  LFVAG +T+ TTL W ++LMAKN  IQD+VH+EI  +IG  ++  V D+KSLPYT AV+ EI R  ++VP+SLPH    +   NG FI K + ++P L +  RD   W+ P  F P+HFL  +     ++   D  +PFS G+R CLGE+LARME F+FFTS++Q F+
Sbjct:   73 YGSVFKVYFGPKKVVVLAGYKTVKQALVNHAEEFGEREVSPMFKKYNEEHGILFSNGENWREMRRFALSNLRDFGMGKRGSEEKIIEEIQYLKEVFESFGGKAFDTTQPVNNAVSNIISSIVYGSRFEYSDPQFKEMVNRANENVRIGGSASVLVYNMFPWTGRFLRSVQKLFV-------NNEKNRVQIRELVKGLQETLNTE-ERRGFVDSFLLRKQIDESNEKA--SYFNEKNLIVTVGNLFVAGTDTSGTTLRWGLLLMAKNPHIQDRVHEEIDRVIGGRQVV-VEDRKSLPYTDAVIHEIQRCANIVPMSLPHVTSCDVHFNGFFIKKGTTVYPLLTSVLRDESEWESPRTFNPDHFLDKQG----QFLKKDAFMPFSAGRRVCLGESLARMELFLFFTSLLQHFR 468
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000030554.1 (cytochrome P450 2B4-like [Source:NCBI gene;Acc:103029841])

HSP 1 Score: 243.817 bits (621), Expect = 8.416e-72
Identity = 162/489 (33.13%), Postives = 257/489 (52.56%), Query Frame = 2 
Query:  251 IYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILF-TDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEF-EEMHAHFRAI---IEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPL 1702
            I+ L+ L +R   P G KPL        +GN+    +   + L +   KYG +    +G + ++V++S +I  +A  + G  FSGR    + + +    GI+  T G  W  QR FAL  L+DFG GK+   E ++ E  +L+KE+ +  GK             N+I  +    RFE D   F  L   +E + +N  F+ +     P+ + +  +   +  F G  Q+F   +H+  + I   +EEHKK  + EN   DFID +L E   +  E   + TF +  +VR   +LF+AG ETT+ TL W +I M  + ++Q++ H+EIV ++G +R P++ D+  LPYT A + EI R  ++VPL + H   + +++ G  +P+ +I+ PNL A   D + WK P  F PE+FL ++     ++   D  +PFS+G R CLGE LAR E FIFFTS++QR K  +     + A    T G  G +R+ L
Sbjct:   29 IFRLNSLRSRN--PPGPKPLL------FVGNMPQFMKDRMA-LIRSMPKYGEMCTVYLGRKPMIVLNSVQIAKEAFIQNGTIFSGRPIMPVTRWINKGYGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEARYLIKEMLKQEGKAFYPSHPIMNSVSNIICSIVFGDRFEYDDRRFAKL---LEIINENIRFLGS-----PVSQVF-NLIPFIKHFRGPHQKFWHNVHSLKKFIFEEMEEHKKTLDPENL-RDFIDAYLVEM--IKQEANEDSTFHEENMVRSTIDLFIAGTETTANTLRWGLIYMMDHPDVQERCHEEIVRVLGFDRFPSMDDRAKLPYTLATVHEIQRYANIVPLGVLHETTQATKLRGYHLPQGTIVMPNLTAIMADKDHWKYPNTFNPENFLDEKG----QFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQRLKFSW----PLGAPPSDTYGVVGAVRSNL 488
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001876.1 (pep scaffold:Pmarinus_7.0:GL477372:10316:22460:-1 gene:ENSPMAG00000001674.1 transcript:ENSPMAT00000001876.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 233.417 bits (594), Expect = 1.309e-68
Identity = 149/481 (30.98%), Postives = 254/481 (52.81%), Query Frame = 2 
Query:  206 FTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIK-EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWK-NIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF-KFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEE----MHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVK 1627
            + +  V+ V+ L L  ++L +        +G  P  GP G PL+GNLF +  + L + L K +  YGP++  ++G   +VV+  N+I+ +AL  +   F  R +  +  K+L +  G+L + G  W  +R F L +L++FG G +   E I+ E  FL++ IE    K   A S   K   NVI  +    R++ +   F K +    E V  + N    I   +P+L+ +P          G  Q   +    ++A  +A IEEH     ++ E  D++D F+ ++ E  +    +  F+D  L+     LFVAG ETTS TL W ++LM    ++Q++V +EI  ++GS R P  +D+  +PYT A + EI R  +++P++ PH    ++++ G F+PK + +   +++  R+  +W+ P +F P HFL  + N    Y+  D +   ++G R CLG+ LARME F+FFT+++QRF  +
Sbjct:   15 WVLLRVVAVLFLWLGFWWLRREQ------RGFPP--GPRGLPLVGNLFQLDLKALPASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDRPEIPVFKKSLGNYEGLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWSQIFNSFPVLKYFP----------GPHQRINKNKVVLNAFIQARIEEHDMA-RIQGEPRDYLDAFIDKRIE--DSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFLDIDGN---FYNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRFSFQ 471
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011205.1 (pep scaffold:Pmarinus_7.0:GL477378:108537:110066:1 gene:ENSPMAG00000010178.1 transcript:ENSPMAT00000011205.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 226.483 bits (576), Expect = 6.309e-66
Identity = 145/475 (30.53%), Postives = 236/475 (49.68%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQ-NKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEE-HKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            GP   P +GN+   K+P  + L + T +YG +    +G   +V +S  + + + L  +G  F+ R      K +    GI+F   G++W   R F L  L++FG GK    + I  E  FL++  ++  G              N+I  +    R+E     F+     VE   Q     + T+  ++P L ++P   +++ +   + ++F       R II E H  R  ++      ID +L +  + DN    N +F++  L+ +  +LF+AG ETTSTTL W ++ M  + EIQ + H+EI  I+GS+R+P + D+ SLPY  AV+ EI R +++VP   PH    + +     IPK +II  N+ +   D   WK P+EF PE+FL ++     K+   D  +PFS G R CLGE LA+ME F+FF S++Q F+  +   +S      +   T    +AP S  +   +R
Sbjct:   56 GPKVIPFLGNVSLFKKPDVA-LDEVTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQK-GSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLGTLCNIFPFLMDFPGPQQIIFKSMAKSKQF------IRDIISERHATRDPIKPMC--LIDAYLSQLEKEDNP---NSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFLDEDG----KFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVSAPTLGYILQIT----KAPKSYKLGLHLR 509
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011254.1 (pep scaffold:Pmarinus_7.0:GL479221:5463:6953:-1 gene:ENSPMAG00000010227.1 transcript:ENSPMAT00000011254.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 220.705 bits (561), Expect = 6.023e-64
Identity = 141/428 (32.94%), Postives = 219/428 (51.17%), Query Frame = 2 
Query:  395 KYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRA----IIEEHKKRFNVENEGEDFIDMFLRE-KYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYA 1660
            KYG +    +G   +V++S  + + + L  +G  F+ R    I   L  N GI     G+ W  QR FAL  L++FGFGK    + IS E  +L++  ++         +L      N+I  L    R++ D   F+ LT  +E + Q +   + IL           +   LL+  G  Q+   +H+  +     I+ EH+   +  N   D ID +L +   E DN    N +FT   L++++ ELF+ G ETTS TL W ++ M  N +IQ + H EI  ++GSER P ++D++SLPY  AV+ EI R  +V+PL + H   ++ + N    PK + +  NL +   D   WK P +F P+HFL D+    I+    D  +PFS G R CLGE+LA+ME F+FFTS++Q F+  +   +S    A
Sbjct:   69 KYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKLTQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFKQETSAFDPHLNL-NNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILC---------NVFPFLLKLPGPWQKVFHIHSKLQCLLNDIVSEHRATKDQHNP-RDLIDSYLAQIDKEKDNP---NSSFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFL-DKDGQCIQS---DAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPNSVSPPTLA 478
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011204.1 (pep scaffold:Pmarinus_7.0:GL477378:78074:79555:1 gene:ENSPMAG00000010177.1 transcript:ENSPMAT00000011204.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 211.846 bits (538), Expect = 9.703e-61
Identity = 146/465 (31.40%), Postives = 233/465 (50.11%), Query Frame = 2 
Query:  290 PKGLKPLHGPSGWPLIGNL--FTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRA----IIEEHKKRFNVENEGEDFIDMFLRE-KYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYA 1660
            P G  P  GP   PL+GN+  F+ K P    + +   KYG +    +G   +V++S  + + + L  +G  F+ R    +   L HN GI     G+ W  QR FAL  L++FGFGK   T+ IS E  +L++  ++   +    + +      N+I  L   +R++ +   F+ LT  +E + Q +   + IL           +   L++  G  Q+   +H   +     I+ EH+   +  N   D ID +L     E DN    N +FTD  L+ ++ ELF+ G ETTS TL W ++ M  N +IQ + H+EI  ++GS+R P + D++SLPY  AV+ EI R  +++P  + H   ++ + N    PK + +  NL +   D   WK P +F P++FL D+    IK    D  +PF  G   C GE+LA+ME F+FFTS++Q F+  +    S    A
Sbjct:   31 PVGFSP--GPKPLPLLGNITAFSCKNPHIG-MQELAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKLTHNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFKQETSE-FDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILC---------NVFPFLIKLPGPWQKVFHIHTKLQCLLKDIVSEHRATKDQHNP-RDLIDSYLAHIDKEKDNP---NRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFL-DKDGQCIK---SDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYWPNSASPPTLA 474
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002462.1 (pep scaffold:Pmarinus_7.0:GL485824:2571:10389:-1 gene:ENSPMAG00000002249.1 transcript:ENSPMAT00000002462.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 176.792 bits (447), Expect = 9.486e-50
Identity = 113/324 (34.88%), Postives = 169/324 (52.16%), Query Frame = 2 
Query:  743 NVIAKLAMNMRFERDTPNFK-FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLRE--KYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQ-DKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPL 1702
            N+I  +    RF+ D   F+  L    E       +   I +  P LE++P   +L+ R + +   F      F+  I EH++      +  D ID +L E  K   D E     TFTD  L+ V+ +LF+AG ET+STTL WA++ M    +IQ ++  +EI  +IG +R PN +D+ +LPYT AV+ E  R+ +V PL + H    + +  G  IPK + +  NL +   D   WK P EF P+HFL    + + ++   D  + FS G R CLGE LARME F+FFTS++QRFK  +    S   +    +  +G  RAP+
Sbjct:   16 NIICSIVFGNRFDYDDKRFRNLLHLFAENFRIEGGWRGKICIFMPWLEDWPGPHQLIFRNADKVNLF------FQERIREHRQTREA-GQPRDLIDAYLDEMEKESQDPES----TFTDGNLLNVVGDLFIAGTETSSTTLRWALLYMMAYPQIQAERCQREIDEVIGGDRSPNTTDRANLPYTDAVIHEAQRMANVAPLGVLHSTTTDVKFRGYNIPKGTKVLLNLTSVLHDETQWKTPNEFNPDHFL----DNTGQFVKPDAFLAFSAGPRVCLGENLARMELFLFFTSLLQRFKFHWPDATSRPNF----VAAEGLSRAPV 320
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Match: ERG5 (C-22 sterol desaturase; a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs [Source:SGD;Acc:S000004617])

HSP 1 Score: 60.8474 bits (146), Expect = 5.001e-10
Identity = 43/193 (22.28%), Postives = 89/193 (46.11%), Query Frame = 2 
Query: 1055 DNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIP--NVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFI-PKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKV 1624
            D+ ++ +  FT+ ++   +F    A  + +S+   W   ++A   ++  K+ +E + +  ++     N+   + + YT  V+ E  R    V L +P+ + +N  ++  +  PK +++ P LY    D EV++ P EF PE ++     GS         + F  G   CLG+        I F +++ +F +
Sbjct:  312 DDSRIYHREFTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRPPV-LMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERWV----EGSKASEAKKNWLVFGCGPHVCLGQTYV----MITFAALLGKFAL 495
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Match: ERG11 (Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation [Source:SGD;Acc:S000001049])

HSP 1 Score: 55.0694 bits (131), Expect = 2.563e-8
Identity = 81/464 (17.46%), Postives = 182/464 (39.22%), Query Frame = 2 
Query:  329 PLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILF-TDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKE-----IEESCGKVISARSLFPKCTVNVIAK--LAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNII-GSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPL-SLPHRLLENSEINGT--FIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESN------------GSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISV 1648
            P +G+        + F  +   KYG +F F +  R + V    K        K    S         T V   G+++         Q+ F    L    F  +    +I+ E     ++     + E     I      P+ T+   ++  L   MR + DT +F +L +++++     NF+            +P +   L  +  R+   + +   + ++I+E +K  ++++   D ID  ++     D  K+     TD ++  ++  + + G  T++ T  W ++ +A+  ++Q ++++E + ++ G ++       + +P     + E  R+    PL SL  +++++  +  T   IP    +  +    H   E +    +F    +  D ++            G+I        +PF  G+ +C+GE  A  +  +  +  ++  K  + +  +V
Sbjct:   64 PWVGSAVVYGMKPYEFFEECQKKYGDIFSFVLLGRVMTVYLGPKGHEFVFNAKLADVSAEAAYAHLTTPVFGKGVIYDCPNSRLMEQKKFVKGALTKEAF--KSYVPLIAEEVYKYFRDSKNFRLNERTTGTIDVMVTQPEMTIFTASRSLLGKEMRAKLDT-DFAYLYSDLDKGFTPINFV------------FPNLP--LEHYRKRDHAQKAISGTYMSLIKERRKNNDIQDR--DLIDSLMKNSTYKDGVKM-----TDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHH--PLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPEGKTV 501
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Match: DIT2 (N-formyltyrosine oxidase; sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively [Source:SGD;Acc:S000002810])

HSP 1 Score: 50.447 bits (119), Expect = 6.635e-7
Identity = 88/425 (20.71%), Postives = 170/425 (40.00%), Query Frame = 2 
Query:  395 KYGPLFKFTMGCRDIVVISSNKILSKALK-EKGIPFSGRWKNIIAKTLVHNSG--ILFTDGEWWATQRSFALKVLKDFGFGKQ-RSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAK-NLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTF-IPKNSIIFPNLYACHRDAEVWKRPFE-FYPEHFLTDESNGSIKYSPMDE---LVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKE 1639
            KYG + KF  G R  +++S ++ L++  K E     SG  K I    L   +G  ++   G  W   R+     L+ F      ++ +I+   C  +   + E     I    L  +  ++ I+++A+   F   T        ++ R+   K       L +P L+  P           R++ F+++   FR ++ +  +   V N   +       +     N +++++     QL   I  + VAG+E        ++ L+AK + E Q+K+ KE+  I   + + +      LP   A + E+ R+   +   +     +  ++     IPK   +  N +    D + W    + F PE + +D       +        +  F  G+R CLGE LA  E  I    ++++F+   + E
Sbjct:   65 KYGAV-KFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAYTGDNVISAYGAVWRNYRNAVTNGLQHFDDAPIFKNAKIL---CTLIKNRLLEG-QTSIPMGPLSQRMALDNISQVALGFDFGALTHEKNAFHEHLIRI--KKQIFHPFFLTFPFLDVLP--------IPSRKKAFKDV-VSFRELLVKRVQDELVNNYKFEQTTFAASDLIRAHNNEIIDYK----QLTDNIVIILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKGLAD------LPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPE 463
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO48207 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK94])

HSP 1 Score: 196.823 bits (499), Expect = 3.879e-55
Identity = 133/441 (30.16%), Postives = 215/441 (48.75%), Query Frame = 2 
Query:  335 IGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGR--WKNIIAKTLVHNSGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKF---LTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIE----EHKKRFNVENEGEDFIDMFLREKYELDNEKVLN--HTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFK 1621
            IGNL  + + +     +    YG +++  +G +  +V+S + I  +AL  +   F+GR      +   L    G+   D GE W   R      +K +G  + R  ++I  E   L   +E S GK             NVI       R++ D P F     +   + R+    N +  I         +P +A +L  FS ++++  ++      I+E    EH K F+ EN   D+ D  L+ K + + E   +  H      ++  +  LF+AG ETTSTTL WA+I +  N ++Q+++HKEI ++IG +  P +S +K LP  +A   E  R+ ++ PL++PH+  E S + G  IP+ + +F NL++ H D  VWK PF F  + FL +E  G  K       +PF  G R CLGE LAR E F+F + ++QRF+
Sbjct:   37 IGNLNLLSKQMHLSFTELEKTYGKVYRLYLGHKLAIVLSGDAI-KEALVRQPRNFAGRPVLNPQLKSALNRGPGLTVMDYGETWKLFRKLGHSTIKVYG--ENRLQDVIKDEVLELCNRLESSAGKPFDITQQSGIAVTNVICTKLFGTRYQIDDPEFLRVYEIHDKLSRIGFGGNLVTNI---------FPSLASIL-PFSEKQRDLIQIGQERYEILERKYQEHVKTFDPENI-RDYTDALLKAKQDAEQEDKSSKEHLQESTIIMAGLATLFIAGSETTSTTLGWAVIYLLHNPDVQERLHKEIDDVIGRDAFPQLSKRKELPVLEAFTAETLRLANLAPLAIPHKARERSTLQGFEIPEGTTVFANLWSLHHDPTVWKDPFTFNLDRFLDEE--GKFKAPVGGTFLPFGAGPRVCLGEVLARSELFLFLSRMLQRFE 461
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO40300 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S7U4])

HSP 1 Score: 187.578 bits (475), Expect = 5.030e-52
Identity = 133/449 (29.62%), Postives = 220/449 (49.00%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVH---NSGILFTD-GEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFK---FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAH----FRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNE-KVLNHTFTDWQLVRV-IFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFK 1621
            GP   PLIGNL  +   +          YG +F+  +  + I+V+S + I  +AL  +   F+GR    I + +V       +   D GE W   R      +K   +G+ R  E+I+ E + L K +EES  K I     F     NVI       R++ + P F+   ++     R+   + ++      +P L+ +       L +S + +E +E+        RA  +EH + F+  N   D+ D  L+ K E + E K     F +  ++   +  LF+AG ETT+TTL+WA+  +  N  +Q ++HKEI  +IG +  P +S +K++P  +A   E  R++++VPLSLPH+   +  + G  I K + +F NL++ H D  +WK P  F  + FL  ++ G  +       +PF  G R CLGE LAR E F+F  +++Q F+
Sbjct:    3 GPRPLPLIGNLNLLSNQMHLDFAALEKTYGKIFRVYLAHKPIIVLSGDAI-KEALVRQPRNFAGRPLLPITEEIVDKRWGPALFAMDYGERWRIFRKLGHSTIK--VYGEDRLQEVINEEVSELCKRLEESDEKPIDITKQFGTAVTNVICTKIFGNRYDINDPEFQRLYYINDKSTRLNIGEGWLKE---AFPFLKPF-------LPYSQQVKEIKELDQERFVIMRAKYDEHVETFD-PNHIRDYTDALLKAKQEAEEEDKSSKEHFGEGPIIMAGLVTLFLAGSETTTTTLSWAIAYLLHNPGVQARLHKEIDQVIGKDVSPKLSQRKNIPVLEAFTAETQRLSNLVPLSLPHKTTSDCTLLGYEIAKGTTVFTNLWSLHHDPSIWKEPDTFNLDRFL--DAKGKFQAPVGGTFLPFGAGPRVCLGEVLARSELFLFLATLLQHFE 435
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO30875 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SZJ0])

HSP 1 Score: 186.422 bits (472), Expect = 1.409e-51
Identity = 131/456 (28.73%), Postives = 223/456 (48.90%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFK-YGPLFKFTMGCRDIVVISSNKILSKALKEKGI-PFSGRWKNIIAKTLVHNSGIL----FTDGEWWATQ--RSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNF----KFLTANVERVAQNKNFIVTILLMYPILEEYP--------RIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNE-KVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            GP+  PLIGNL +IK     F      K +G +    +    IVV++S  +  + L  K I  F+GR K    + +      +    ++ G  W  +   S   K     G       + I+ E A L  ++    G  + ++  F    +N+I        F+++ P F    +F+T  V+ ++ +     +IL  +P L  +P        RIA+L  +  G              I+  HK+ FN EN   D  D FL+ K +++ E K      TD ++  ++ ++++AG ETT T+L W +  +  N E+Q +V   I ++IG  R P +SD++ LPY +A++ E+ R++  +PL LPH+ + ++ I+G  IPK + +  NL+A H D   W  P +F P+ F+ +  +G  +       +PF  G+R CLGE+LA+ME F+  T ++Q+F
Sbjct:    4 GPTPLPLIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLRKYFPSLG-------DTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLTGKAFDKEDPEFSETLEFVTMTVDTISMS----ASILDAFPFLIHFPLQASKNFKRIAELRDKLMGN-------------ILTFHKETFN-ENHIRDLTDAFLKAKLDIEREDKKAAEEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIGDRR-PLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFINE--DGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO29403 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T3R2])

HSP 1 Score: 186.808 bits (473), Expect = 1.859e-51
Identity = 127/472 (26.91%), Postives = 226/472 (47.88%), Query Frame = 2 
Query:  227 VVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGR--WKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEE-YPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEG--EDFIDMFLREKYELDNEKVLNHTFTDWQLVRV-IFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            ++I+LAL   F S+    P          GP+ WP+IGNL  +  KE L+      + KYG +F+  +G + +VV++   I     ++  + F+GR      +   +  + G+L   G  W   +      ++    G  R  E I  E   + + ++   G+ +     F   T NVI       R++   P F        R+ +  N I  +++    L + +P +  +L     R +  E +   +  I  ++K+       G   D+ D+ +  K    N    +H  T+  ++   +   F+AG ETT++TL+W+++ +  + ++Q+++H E+ ++IG  ++P +S KK LP  +A   E  R++ + PL +PH+   ++ + G  IPK + + PNL++ H D+  WK PF+F    FL D   G  +    D  +PFS G R CLGE LAR E F+F   ++Q+F
Sbjct:    9 LLISLALIYIFYSRKERLPP---------GPAPWPIIGNLDLLIRKEALYKTFTNLSHKYGGVFRLYLGSKPVVVLNGKAIYDSLARQPSV-FAGRPTLPPSLDFGMDPDYGVL-DYGPLWKFYKKLGHSAVR--VHGTDRLNEAIRVEVDEVCRRLDSLDGQPVDISKEFGIATTNVICARLFGSRYDVHDPEFL-------RIYEIHNKISRVVMSSRSLSDVFPFLVNILPESKERRELRELLQERYTIIWRKYKEHEQTFTPGVIRDYTDLLIDAKLSEKN----SHKLTENGIISTGLASQFLAGSETTASTLSWSVVYLLNDSDVQERIHNELDDVIGKGQLPQLSHKKKLPVLEAFTAETLRLSCIGPLGMPHKTTRDTFLRGHAIPKGTTVVPNLWSLHHDSTEWKDPFKFDINRFLED---GVFRAPANDAYLPFSAGPRVCLGEELARSELFLFLARLLQKF 453
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Match: EDO30239 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1C7])

HSP 1 Score: 185.267 bits (469), Expect = 3.236e-51
Identity = 129/452 (28.54%), Postives = 217/452 (48.01%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTIKEPLWSFLYKQTFK-YGPLFKFTMGCRDIVVISSNKILSKALKEKGI-PFSGRWKNIIAKTLVHNSGIL----FTDGEWWATQ--RSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYP--------RIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNE-KVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            GP+  PLIGNL +IK     F      K +G +    +    IVV++S  +  + L  K I  F+GR K    + +      +    ++ G  W  +   S   K     G       + I+ E A L  ++    G  + ++  F    +N+I        F+++ P F      V +     +   +IL  +P L  +P        RIA+L  +  G              I+  HK+ FN EN   D  D FL+ K +++ E K      TD ++  ++ ++++AG ETT T+L W +  +  N E+Q +V   I ++IG  R P +SD++ LPY +A++ E+ R++  +PL LPH+ + ++ I+G  IPK + +  NL+A H D   W  P +F P+ F+ +  +G  +       +PF  G+R CLGE+LA+ME F+  T ++Q+F
Sbjct:    4 GPTPLPLIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWKRKIVHSGLRKYFPSLG-------DTIAKELAKLEDKLNSDVGVPVDSKDEFFLLVLNIICSFLSGKAFDKEDPEFSETLELVTKTVDTLSMSASILDAFPFLIHFPLQASKNFKRIAELRDKLMGN-------------ILTFHKETFN-ENHIRDLTDAFLKAKLDIEREDKKAAGEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIGDRR-PLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFINE--DGKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000019638.2 (cytochrome P450 2K1 [Source:NCBI gene;Acc:101157991])

HSP 1 Score: 263.462 bits (672), Expect = 5.039e-79
Identity = 168/486 (34.57%), Postives = 258/486 (53.09%), Query Frame = 2 
Query:  179 LDIIN*IKMFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFR----AIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            + I++  + ++   ++ ++A+ L +YF+S+ +   S   G +P  GP   P+IGNL  I  K P +  L + +  YGP+F    G   +VV++  K +  AL      F  R    I + L    G+L+++G+ W   R FAL  L+DFG GK+   + I+ EC +LL+  ++  G              N+I  +    RFE D P F   T+ V+R  +N       L   P L+ Y  +   L ++    +E  E  A  R    +I    K+  N +     F+D FL +   L+   V N  F D  L+  +  LF AG ETTSTTL W ++LMAK  +IQD+V  E+  +IG +R+  VSD+K+LP+T AV+ EI R+ S+VP +LPH+  ++    G FI K + +FP L +   DA  W++P  FYP HFL  +     K+   +  +PFS G+R CLGE+LARME F+FFT+++Q F
Sbjct:    1 MQILDFFQSYSSVSLVGILAV-LVLYFISQFIFN-SEQHGQEP-PGPRPLPIIGNLMQIDLKRP-YKTLEEFSKTYGPVFTVFFGGEKVVVLAGYKTVKNALVNHDEEFGERAIPPIIQELNKGLGVLWSNGDIWRDIRRFALTNLRDFGMGKKACEDKITEECQYLLEVFKKFKGNAFDTTKPLNYAVSNIICSMVYGSRFEYDDPKF---TSMVDRTNRNIQ-----LSGSPTLQAY-NMVPWLFKWVASRREVHECAAANRKQNQSIFSHLKETLNPQ-MCRGFVDAFLVKGQTLEKSGVTNSAFNDENLLMTVIHLFAAGTETTSTTLRWGLLLMAKYPKIQDQVQDELRRVIG-DRMVQVSDRKNLPFTDAVIHEIQRLASIVPTALPHKTSKDVTFQGYFIKKGTTVFPLLTSVLHDANEWEKPHTFYPAHFLDKDG----KFVKREAFIPFSAGRRICLGESLARMELFMFFTTLLQNF 467
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000018818.2 (cytochrome P450 2J2 [Source:NCBI gene;Acc:101157767])

HSP 1 Score: 249.21 bits (635), Expect = 8.374e-74
Identity = 154/475 (32.42%), Postives = 241/475 (50.74%), Query Frame = 2 
Query:  290 PKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQ-TFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQ-NKNFIVTILLMYP-ILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLS 1705
            PK   P  GP   P IG+L  I+  +    +K+   KYG +F   +     VV++  K+L +AL +KG  F  R +  +   L+ N GI+ T+G  W  QR FAL  L++FG GK+   + I  EC ++ +   E  GK   A+ L      N+I  L    RFE     ++ +  ++  V +   +F      ++P +++ +P   + L     +  +F ++       IEEHK+  +     +D+ID FL    E++  +  +  F    L     +LF AG ETT+TTL W ++ M    +IQ++VH EI  +IGS R P+++DK+++PYT AV+ EI R+  +VP+ +      ++ ++   IPK ++I P L+    D  VW+ P  F P+HFL  +      +   +   PF  GKR CLGE LARME F+FFTS +QRF        +         G  GTIR+P S
Sbjct:   37 PKNFPP--GPRSLPFIGDLHRIRPTILHLQFKEFAAKYGNVFSLNIFGGKTVVLNGTKLLKEALIQKGDDFVDRPQIPLFSDLIENKGIVMTNGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVKLQGSFSALAYNVFPWLMKRFPGPLQKLFTLVDKIMDFVKIK------IEEHKENLDPACP-KDYIDSFL---IEMEKNQGEDFGFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFLNQDGT----FKKREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRFSFS-----TAGGEKPPLEGRMGTIRSPKS 490
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: cyp2n13 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101156965])

HSP 1 Score: 249.21 bits (635), Expect = 8.685e-74
Identity = 162/477 (33.96%), Postives = 241/477 (50.52%), Query Frame = 2 
Query:  314 GPSGWPLIGNLFTI--KEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGR-WKNIIAKTLVHNS-GILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGRE-QEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            GP G P +GN  TI  K P   F  K    YG +F   +G +  V +S  K++ +AL  +   F  R +  I  +    NS G+ F++GE W  QR FAL  L+ FG GK    + I  E   L ++IE   G   S   LF     N+I +L M  RF+ D  NF+ +   +    Q +  I  IL      E +P + K L     +  + ++ +       I+ HK+  +  N   D+ID F+ E  +  N  +    F D  L     +LFVAG ETTSTTL WA+I + K+ ++Q KV +EI  +IG  R+P+++D+ +LPYT AV+ EI R+ ++VPL+      +++ + G FIPK + + P L +   D   W+ P  F PEHFL  +     K+   +  +PFS GKR CLGE LARME F+F   ++Q+F     + + +      T G  GT R P    V  ++R
Sbjct:   40 GPLGLPFVGNFLTIDGKHPHIYF-SKMAESYGNVFSVRLGSQATVFVSGYKMVKEALVTQAENFVDRPFSEIGGRFYEGNSNGLFFSNGEKWKKQRRFALSTLRTFGLGKNTMEQSICEEIRHLQQQIENEKGGPFSPAGLFNNAVSNIICQLVMGKRFDYDDNNFQVMMKYISEAVQLEGSIWGILY-----ESFPGLMKHLPGSHNKIFRNYKIVQDFLAQEIKIHKQDLDPNNP-RDYIDSFIIEMEKHQNSDL---GFNDANLAFCSLDLFVAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVVHEIQRIGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFLDADG----KFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGVELS-----TEGITGTTRVPHPYKVYAKVR 497
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000020799.2 (cytochrome P450 2J6 [Source:NCBI gene;Acc:101155419])

HSP 1 Score: 239.58 bits (610), Expect = 5.073e-70
Identity = 160/453 (35.32%), Postives = 230/453 (50.77%), Query Frame = 2 
Query:  341 NLFTIK--EPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILL--MYPILEEYPRIAKLLLRFSGREQEF--EEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEIS--VDAYAKMTMG 1675
            N+FT+    P  SF  K   +YG L+    G R  VV++ +K L +AL  KG     R    +   +    G++F++G  W  QR FAL  L+ FGFGK+    +I +E A   +E++   G+ +    +      N+I  L    RF      FK L    +R  Q +  I   L      I+   P   K L       Q+F  EE+        +EHKK ++  ++  D+ID +L E  +   ++    TF +  L+  + +LFVAG ETTSTTL WA + MAK  EIQ+KV  EI  +IG  R P + D+  LPYT AV+ E+ R+ ++VPLSLPH   ++ ++ G  IPK  +I PNL +   D + W+ P  F P HFL  +     K+      +PFS GKR CLGE LARME F+FFTS MQ F       +   +D  A +T+ 
Sbjct:   76 NIFTVDVGRPHESF-SKLAAEYGDLYSLRFGQRWTVVLNGHKALKEALVTKGDSVVDRPHLPLQDEIAKGLGVIFSNGANWTEQRRFALSTLRYFGFGKKSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEASIWAQLYNSFTLIMRCLPGPHKTLQHIWREVQDFIGEEL--------KEHKKSWD-PSDARDYIDFYLTEIQKTKGQE--GSTFDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPPCMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFLNKDG----KFVKRGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFSMPAGVEPVLDYRAGLTLA 512
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Match: ENSORLT00000010152.2 (cytochrome P450 2K1 [Source:NCBI gene;Acc:101174506])

HSP 1 Score: 230.72 bits (587), Expect = 6.564e-67
Identity = 139/408 (34.07%), Postives = 221/408 (54.17%), Query Frame = 2 
Query:  398 YGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANV-ERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRF 1618
            YGP+F    G + +VV++  K + +AL      F  R    + + +    GILF +GE W   R FAL  L+DFG GK+ + E I  EC +L++ +E+  G  +         T N+I+ +    RF+ D P F+ L +   E +  N + +  +  M+P    + +  K++L         E      + +++  K+  N  +    F+D FL +K + ++  V    FT+  LV  +  LF AG +TT+TTL W ++LMAK   IQDKVH+E+  ++G  ++  V D+K+LPY  AV+ EI RV +++P+S+PH+   +   +G  I K + + P L +   D   W+ P  F P HFL+ E     K+   D  +PFS G+R CLGE+LA+ME F+FFTS++QRF
Sbjct:   71 YGPVFTVYFGIQKVVVLAGYKTVKEALVNNAEEFGDRDITPMFQDMNKGHGILFANGESWKELRRFALTTLRDFGMGKRIAEEKILEECDYLIQGLEKHQGNPVDLTCPLNYATSNIISSIVYGSRFDYDDPRFRNLVSRANETIRINGHPLTHLYNMFPRWFRWIKNRKIIL------NNVEMTVKDVKDLVKHLKETLN-PSVCRGFVDCFLIKKQKEEDSCVKESHFTEQNLVFSVSNLFAAGTDTTATTLRWGLLLMAKYPHIQDKVHEELAKVLGGRQV-RVDDRKNLPYADAVIHEIQRVANIIPMSIPHKTNRDVTFHGYLIQKGTTVIPLLASVLNDENEWESPHTFNPHHFLSKEG----KFVKRDAFMPFSAGRRACLGESLAKMELFLFFTSLLQRF 466
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000013697.1 (SMESG000013697.1)

HSP 1 Score: 1038.1 bits (2683), Expect = 0.000e+0
Identity = 505/509 (99.21%), Postives = 506/509 (99.41%), Query Frame = 2 
Query:  203 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPL GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIA TLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTW MILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLT+ESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR
Sbjct:    1 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLQGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAITLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWTMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTEESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 509
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000020470.1 (SMESG000020470.1)

HSP 1 Score: 680.248 bits (1754), Expect = 0.000e+0
Identity = 318/503 (63.22%), Postives = 403/503 (80.12%), Query Frame = 2 
Query:  221 VIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            V++ I L + +YF+ K     S  K L  L GP+GWPLIGN+ +  EPLW  LYK +  YG LFK+TMG RDIV++SS+K+L K LKE+G  FSGR++N + K    NSGILFT+ EWWATQRSFALKVL+DFGFGKQRS EI+S+EC  LLK+IEE CGKV+SARSLFPK TVNVIAKL MNMRFE D+ +F  LT  +E+  QN NFI+T+  MYPIL+  P IA  LL +SGR +  +        II++HKKRFN+ENEGEDFID+FL+E+++L+ EKV NHTFTD QL+RV+ ELF AGYETTSTTL+W+M+L+AK+  IQ+KV++EIV+++G+E++PN +DKK L YTQAVMDEI RV++VVPLS+ HR+ EN+E++G +IPK+SIIFPNL+ACHRD  VW++PFEFYPEHFL   ++G +KY+P DELVPFSIGKRQCLGE LAR+EFFIF T I+Q+FK++FE EIS + +AK+T GTDG IRAPLSSDVVFE+R
Sbjct:    5 VLIFITLGIALYFIKKFFFNQSASKNLNLLQGPTGWPLIGNINSFNEPLWMVLYKYSKHYGSLFKYTMGRRDIVILSSSKMLFKTLKEQGNNFSGRFQNFLIKARTRNSGILFTEKEWWATQRSFALKVLRDFGFGKQRSQEIVSNECMILLKDIEEECGKVVSARSLFPKATVNVIAKLVMNMRFESDSKDFTELTKLIEKAIQNNNFILTLFQMYPILDNMPFIAPFLLWWSGRNKTAKITSKFINNIIDDHKKRFNIENEGEDFIDIFLKEQHKLNEEKVKNHTFTDQQLIRVVLELFFAGYETTSTTLSWSMLLLAKHPNIQEKVYQEIVDLLGTEKLPNFADKKCLQYTQAVMDEILRVSTVVPLSISHRVFENTEVDGVYIPKDSIIFPNLFACHRDENVWEKPFEFYPEHFLNINNSGQLKYTPRDELVPFSIGKRQCLGEGLARIEFFIFLTGIIQKFKIRFENEISEEEFAKITRGTDGGIRAPLSSDVVFELR 507
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000034110.1 (SMESG000034110.1)

HSP 1 Score: 613.609 bits (1581), Expect = 0.000e+0
Identity = 284/510 (55.69%), Postives = 389/510 (76.27%), Query Frame = 2 
Query:  203 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILE-EYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            M T+  V++ I L + +YFLS+  +   IP GL+PL GPSGWPL+GNLF+IKEPLWS  YK    YG +FKF +G R++V+I+S+KIL K LK++G+ FSGR +N + K + H+ GI+F + EWW+TQRSFALKVL+DFG GKQRS EI+++EC+ LL+E+EE+ GK I  +S FP  TVN+IAKL MNMRFE+++  F      +E+   N++F+V +  +Y +     P IA    RFSG     + +H     II E KK F+ ENEG+DFIDMFL EK++L++E V NHTFTDWQL+R++ ELF AG+E+TSTTL+WAM+L+A++ EIQDKVH+EI+N+IG ++IP++++KK L YTQAVMDEI R+++V PL++PHR+  ++E+ G +IPK+S IF NLYACHRD +VW++PF+FYPEHFLT   NG +KY+P +ELVPFS GKRQC GE+LAR+E+F+F TSI+Q+FK+KF K I    Y K+T GTDGT+RAPL  D++FE+R
Sbjct:    1 MITLLNVLISIFLVIILYFLSRKFSTNPIPIGLRPLQGPSGWPLVGNLFSIKEPLWSIFYKHAKTYGEIFKFKLGNRELVIINSSKILFKTLKDQGVNFSGRQQNDLIKYITHDCGIVFKEKEWWSTQRSFALKVLRDFGLGKQRSIEIVNNECSILLQELEETSGKNICTKSCFPSVTVNIIAKLLMNMRFEKNSSEFFEFRKIIEQTTHNRSFLVILFQIYTLPHFTIPFIA----RFSGLRNHIDAVHNFVINIINERKKTFSHENEGQDFIDMFLIEKHKLESENVKNHTFTDWQLIRMVVELFGAGFESTSTTLSWAMVLLARHTEIQDKVHQEIINLIGVDKIPDLNNKKFLHYTQAVMDEILRISTVAPLAVPHRVFNDAEVEGFYIPKDSTIFTNLYACHRDEKVWEKPFDFYPEHFLTKLDNGEMKYTPREELVPFSTGKRQCPGESLARLEYFVFLTSILQKFKIKFNKAIDDITYEKITRGTDGTVRAPLDVDLIFEMR 506
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000013700.1 (SMESG000013700.1)

HSP 1 Score: 509.99 bits (1312), Expect = 5.241e-178
Identity = 245/262 (93.51%), Postives = 255/262 (97.33%), Query Frame = 2 
Query:  203 MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKK 988
            MFTIFE+IVVI LALPIYFLSKL+TRPSIPKGLKPL GPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNII KT+  NSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTAN+ER+AQN NFIVTILLMYPILEEYPRIAKLLLRFSGR+QEFE +HA+FRAI+E+HKK
Sbjct:    1 MFTIFEIIVVIVLALPIYFLSKLVTRPSIPKGLKPLQGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIIKTIALNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANIERIAQNNNFIVTILLMYPILEEYPRIAKLLLRFSGRDQEFEVIHAYFRAIVEKHKK 262
[Close]
BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Match: SMESG000078091.1 (SMESG000078091.1)

HSP 1 Score: 490.73 bits (1262), Expect = 1.167e-166
Identity = 231/493 (46.86%), Postives = 331/493 (67.14%), Query Frame = 2 
Query:  251 IYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFTIKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFSGRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEIISHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFKFLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMHAHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLVRVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPNVSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIFPNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQCLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPLSSDVVFEIR 1729
            +YFL  +  +P IPKGLK +   SG P+IG +  I+ P+  +L K   K GP+F+  +G R IVV+++ +++ KAL +    FSGRW     K + H+SGI+F DG+ WATQRSF LKVL+DFG GK +S EI+ +EC   L E++   G+++    L P  T N+I++  MN RF RD PN + +   +    +NK+ I  ILLM+P  +    I +L+   + + + F ++  +F   IEEH+   ++ +EGED +D FL +++EL        +F DWQL+R   ELF+AGYETTSTTL W  + M+K  +IQ+KVHKEI  IIG ER+P ++DKK+L YTQAVMDE+ R++SV P+ L HR  +++ ING +IPK+S+IFPNLYACH D E+W+ P  FYPEHFL+ +SNG  KY P +EL+PFS+GKRQCLGE+LAR E+FIFF S++QRF++ F +EIS D Y++  +G +G IR     + +F+ R
Sbjct:   14 LYFLYWVCRKPPIPKGLKEIPMESGLPIIGAIHKIEPPMHHYLLKLGRKLGPIFRIKLGMRKIVVLNNYEMIKKALIDDANNFSGRWSQRFIKEITHDSGIIFKDGKIWATQRSFILKVLRDFGLGKSKSIEIVQNECFNFLDELDTLSGQIVDFSELIPIYTTNIISRFIMNKRFTRDDPNIQLIEETINNSTKNKDIIQLILLMFPCFDNSSLICQLIYLLTSKWKSFVKIQNYFGEEIEEHRTNLDLTSEGEDLMDRFLIKQHELKQSTGNVESFVDWQLIRTSVELFIAGYETTSTTLNWCCLFMSKYPDIQEKVHKEISEIIGKERLPTMNDKKALNYTQAVMDEVLRLSSVAPMGLIHRTFDDANINGFYIPKDSLIFPNLYACHMDPEIWESPTTFYPEHFLSLDSNGISKYQPREELIPFSVGKRQCLGESLARSEYFIFFVSMVQRFQISFAEEISEDKYSQTIIGNEGVIRTSDIKNFLFKRR 506
The following BLAST results are available for this feature:
BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CYP2A132.818e-7234.92cytochrome P450 family 2 subfamily A member 13 [So... [more]
CYP2A69.513e-7233.11cytochrome P450 family 2 subfamily A member 6 [Sou... [more]
CYP2U18.043e-7130.39cytochrome P450 family 2 subfamily U member 1 [Sou... [more]
CYP2A74.336e-7034.47cytochrome P450 family 2 subfamily A member 7 [Sou... [more]
CYP2J21.170e-6533.63cytochrome P450 family 2 subfamily J member 2 [Sou... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp-33C92.126e-6531.15CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33D11.525e-6330.77CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-23A16.507e-6331.34CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33D31.527e-6230.58CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
cyp-33C14.471e-6230.71CYtochrome P450 family [Source:UniProtKB/TrEMBL;A... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cyp18a11.709e-6030.49gene:FBgn0010383 transcript:FBtr0074610[more]
Cyp18a11.709e-6030.49gene:FBgn0010383 transcript:FBtr0074609[more]
Cyp303a19.596e-4726.71gene:FBgn0001992 transcript:FBtr0343812[more]
Cyp303a19.596e-4726.71gene:FBgn0001992 transcript:FBtr0080828[more]
Cyp305a17.991e-4426.86gene:FBgn0036910 transcript:FBtr0074925[more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cyp2y34.899e-7735.54cytochrome P450, family 2, subfamily Y, polypeptid... [more]
cyp2y31.487e-7635.31cytochrome P450, family 2, subfamily Y, polypeptid... [more]
cyp2k217.108e-7234.73cytochrome P450, family 2, subfamily k, polypeptid... [more]
cyp2n132.789e-7132.62cytochrome P450, family 2, subfamily N, polypeptid... [more]
CU179648.24.598e-7132.64cytochrome P450 2F2-like [Source:NCBI gene;Acc:100... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
cat11.883e-8737.21calcium transporter 1 [Source:Xenbase;Acc:XB-GENE-... [more]
parp111.170e-8536.43poly(ADP-ribose) polymerase family member 11 [Sour... [more]
tuba1c2.287e-8436.51tubulin alpha 1c [Source:Xenbase;Acc:XB-GENE-49384... [more]
ENSXETT00000021944.12.410e-8436.20cytochrome P450 2K1-like [Source:NCBI gene;Acc:100... [more]
cyp2f12.417e-7332.91cytochrome P450 2K1 [Source:NCBI gene;Acc:10049047... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cyp2j63.679e-7433.19cytochrome P450, family 2, subfamily j, polypeptid... [more]
Cyp2b191.710e-7232.29cytochrome P450, family 2, subfamily b, polypeptid... [more]
Cyp2a125.836e-7232.89cytochrome P450, family 2, subfamily a, polypeptid... [more]
Cyp2f21.233e-7134.00cytochrome P450, family 2, subfamily f, polypeptid... [more]
Cyp2j123.517e-7132.41cytochrome P450, family 2, subfamily j, polypeptid... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P00178|CP2B4_RABIT2.387e-7433.63Cytochrome P450 2B4 OS=Oryctolagus cuniculus OX=99... [more]
sp|P12938|CP2D3_RAT4.948e-7433.33Cytochrome P450 2D3 OS=Rattus norvegicus OX=10116 ... [more]
sp|P24461|CP2G1_RABIT1.121e-7332.26Cytochrome P450 2G1 OS=Oryctolagus cuniculus OX=99... [more]
sp|O54750|CP2J6_MOUSE2.573e-7333.19Cytochrome P450 2J6 OS=Mus musculus OX=10090 GN=Cy... [more]
sp|P10610|CP2G1_RAT1.004e-7232.96Cytochrome P450 2G1 OS=Rattus norvegicus OX=10116 ... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4P8NYX52.627e-16548.65P450 2B-like protein OS=Dugesia japonica OX=6161 G... [more]
A0A2U8U4736.044e-15243.91Cytochrome P450 2K1-like protein OS=Dugesia japoni... [more]
A0A267GWC92.385e-8634.03Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A1I8IP399.536e-8633.65Uncharacterized protein OS=Macrostomum lignano OX=... [more]
A0A267H3D95.331e-8533.65Uncharacterized protein OS=Macrostomum lignano OX=... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000052034.12.699e-7636.68pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000019491.24.167e-7636.67pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
cyp2n132.558e-7534.62cytochrome P450 2J6-like [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000019474.21.262e-7236.50cytochrome P450 2K1-like [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000030554.18.416e-7233.13cytochrome P450 2B4-like [Source:NCBI gene;Acc:103... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSPMAT00000001876.11.309e-6830.98pep scaffold:Pmarinus_7.0:GL477372:10316:22460:-1 ... [more]
ENSPMAT00000011205.16.309e-6630.53pep scaffold:Pmarinus_7.0:GL477378:108537:110066:1... [more]
ENSPMAT00000011254.16.023e-6432.94pep scaffold:Pmarinus_7.0:GL479221:5463:6953:-1 ge... [more]
ENSPMAT00000011204.19.703e-6131.40pep scaffold:Pmarinus_7.0:GL477378:78074:79555:1 g... [more]
ENSPMAT00000002462.19.486e-5034.88pep scaffold:Pmarinus_7.0:GL485824:2571:10389:-1 g... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 3
Match NameE-valueIdentityDescription
ERG55.001e-1022.28C-22 sterol desaturase; a cytochrome P450 enzyme t... [more]
ERG112.563e-817.46Lanosterol 14-alpha-demethylase; catalyzes C-14 de... [more]
DIT26.635e-720.71N-formyltyrosine oxidase; sporulation-specific mic... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO482073.879e-5530.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO403005.030e-5229.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO308751.409e-5128.73Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO294031.859e-5126.91Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO302393.236e-5128.54Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000019638.25.039e-7934.57cytochrome P450 2K1 [Source:NCBI gene;Acc:10115799... [more]
ENSORLT00000018818.28.374e-7432.42cytochrome P450 2J2 [Source:NCBI gene;Acc:10115776... [more]
cyp2n138.685e-7433.96cytochrome P450 2J6 [Source:NCBI gene;Acc:10115696... [more]
ENSORLT00000020799.25.073e-7035.32cytochrome P450 2J6 [Source:NCBI gene;Acc:10115541... [more]
ENSORLT00000010152.26.564e-6734.07cytochrome P450 2K1 [Source:NCBI gene;Acc:10117450... [more]
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BLAST of Cytochrome P450 2K1-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000013697.10.000e+099.21SMESG000013697.1[more]
SMESG000020470.10.000e+063.22SMESG000020470.1[more]
SMESG000034110.10.000e+055.69SMESG000034110.1[more]
SMESG000013700.15.241e-17893.51SMESG000013700.1[more]
SMESG000078091.11.167e-16646.86SMESG000078091.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035502 ID=SMED30035502|Name=Cytochrome P450 2K1-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=2280bp
TTTGAACATAGGAGTCAAGTTATAGTCCAGAATAATTCAATCACAACACT
TACTGATAAATATTTTTCAAAGTGCAAAATTTTAATTATCTGTGACAATG
CCGTTTCGGTTAGTTTATTCGCAATTCACCTTTATCACCATCTTTATTGA
TATATTTAATTGATTTTTGCACATAGATTTAGACATTATAAACTAGATCA
AAATGTTCACAATATTTGAAGTTATTGTTGTCATTGCTTTAGCTTTGCCA
ATATATTTCCTATCAAAGCTAATGACAAGGCCTTCAATTCCAAAAGGACT
GAAACCTTTACATGGACCAAGTGGTTGGCCATTGATAGGCAATCTTTTTA
CGATTAAAGAACCTTTATGGAGCTTTCTTTACAAGCAAACTTTTAAATAT
GGCCCGCTTTTCAAATTTACTATGGGTTGTCGAGATATCGTTGTTATCAG
TTCAAACAAAATCCTTTCAAAAGCTCTAAAAGAAAAAGGAATTCCATTTT
CTGGAAGATGGAAAAACATTATTGCTAAAACCCTTGTTCATAATTCAGGT
ATTCTATTTACGGATGGAGAGTGGTGGGCAACTCAGAGAAGTTTTGCGTT
GAAAGTTTTAAAAGACTTTGGATTTGGAAAACAAAGATCCACCGAAATAA
TAAGCCATGAATGTGCATTTTTACTTAAGGAAATTGAAGAGAGTTGTGGA
AAAGTTATCAGTGCAAGATCACTATTTCCGAAATGCACAGTGAATGTCAT
TGCAAAACTGGCAATGAATATGAGATTTGAAAGAGATACTCCAAATTTCA
AATTCTTAACAGCAAATGTAGAGAGGGTAGCCCAAAACAAAAACTTCATT
GTTACAATATTACTTATGTATCCGATTCTTGAAGAGTATCCTAGGATTGC
AAAGCTTTTGTTACGGTTCAGTGGAAGAGAACAGGAATTTGAAGAGATGC
ACGCTCATTTCAGAGCAATTATTGAAGAACATAAAAAACGATTTAATGTA
GAAAATGAAGGTGAAGATTTTATTGATATGTTTCTTCGAGAAAAATATGA
ACTTGACAACGAAAAGGTTCTTAATCACACATTCACTGACTGGCAACTAG
TCAGAGTTATCTTTGAACTGTTTGTTGCAGGATATGAAACGACTTCAACT
ACATTGACATGGGCAATGATTTTAATGGCAAAAAATTTAGAAATTCAAGA
CAAAGTCCATAAAGAAATAGTTAATATAATTGGCTCAGAAAGAATTCCGA
ATGTTAGTGATAAAAAATCTCTTCCCTATACTCAAGCAGTAATGGATGAA
ATATTTCGCGTCACCTCCGTTGTTCCTCTCTCTTTGCCACACAGACTTCT
TGAGAATTCTGAAATCAACGGAACATTCATTCCTAAAAATTCGATAATTT
TCCCTAATCTTTATGCTTGTCACCGTGATGCAGAAGTATGGAAACGTCCT
TTTGAATTTTATCCGGAACACTTCTTAACTGATGAAAGTAACGGCTCAAT
TAAATACTCTCCAATGGATGAATTGGTTCCATTTAGCATTGGCAAACGAC
AATGCTTGGGAGAAGCATTGGCAAGAATGGAGTTCTTTATATTTTTCACA
AGTATCATGCAACGATTCAAAGTAAAATTTGAAAAGGAAATAAGCGTGGA
TGCTTATGCTAAAATGACCATGGGAACTGACGGTACTATCCGAGCCCCCC
TGAGCTCAGATGTTGTGTTTGAAATAAGATAAATTACCCAATTTGGTATC
AAAAAACTGAATATATCTGCTTATCTACAAATATAATCCACACTATTCCT
AAATTTTTAATAATTATTAAATAAACATTTTATTTGTAATTGTAAATATT
CAATAAAATTTGTTTGTCTAACTCAGGATTACTTTTCGAAATATTTTTAA
AAAGCACGAAGAGATATAAAGGCTGTTACGGATAAGGAAAAAGATCTGAT
GATTTATGTATTTTCAATCCACCATTTTTGGATCTAATTAATAAGTAGTC
TGTTACTTTGACTCATTGTGCACTTTCATAGTAAATAAATAACGTATATT
GAATTATTATATATTTGTATAATTCAATTGTGACAGTAAATATCTTATAG
TCCGGTCACTACAGCTACTGGCTGTCGAAATAACGCGCAATAATATTTCA
CCTTTTGTAATGTGCCAAATGATTTCAATGATCTTTCAAATGATGGTCTA
TTCTGGTGTAAGTTCTTTCAATTACGAAATCTTTCTTTAAATTTGTAGCA
TTTAATTATATTTTATAATAAAAGTTTTGC
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protein sequence of SMED30035502-orf-1

>SMED30035502-orf-1 ID=SMED30035502-orf-1|Name=SMED30035502-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=510bp
MFTIFEVIVVIALALPIYFLSKLMTRPSIPKGLKPLHGPSGWPLIGNLFT
IKEPLWSFLYKQTFKYGPLFKFTMGCRDIVVISSNKILSKALKEKGIPFS
GRWKNIIAKTLVHNSGILFTDGEWWATQRSFALKVLKDFGFGKQRSTEII
SHECAFLLKEIEESCGKVISARSLFPKCTVNVIAKLAMNMRFERDTPNFK
FLTANVERVAQNKNFIVTILLMYPILEEYPRIAKLLLRFSGREQEFEEMH
AHFRAIIEEHKKRFNVENEGEDFIDMFLREKYELDNEKVLNHTFTDWQLV
RVIFELFVAGYETTSTTLTWAMILMAKNLEIQDKVHKEIVNIIGSERIPN
VSDKKSLPYTQAVMDEIFRVTSVVPLSLPHRLLENSEINGTFIPKNSIIF
PNLYACHRDAEVWKRPFEFYPEHFLTDESNGSIKYSPMDELVPFSIGKRQ
CLGEALARMEFFIFFTSIMQRFKVKFEKEISVDAYAKMTMGTDGTIRAPL
SSDVVFEIR*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000018Category 4 cell
PLANA:0000026gut
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR036396Cyt_P450_sf
IPR001128Cyt_P450
IPR002401Cyt_P450_E_grp-I
IPR017972Cyt_P450_CS
Vocabulary: molecular function
TermDefinition
GO:0005506iron ion binding
GO:0020037heme binding
GO:0016705oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0004497monooxygenase activity
GO:0016491oxidoreductase activity
GO:0016712oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
GO:0046872metal ion binding
Vocabulary: biological process
TermDefinition
GO:0055114oxidation-reduction process
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002401Cytochrome P450, E-class, group IPRINTSPR00463EP450Icoord: 87..108
score: 24.47
coord: 63..82
score: 33.64
IPR002401Cytochrome P450, E-class, group IPRINTSPR00463EP450Icoord: 243..267
score: 39.95
coord: 159..185
score: 32.46
coord: 202..220
score: 39.17
coord: 282..292
score: 55.37
coord: 139..156
score: 39.76
coord: 292..315
score: 46.97
coord: 19..37
score: 25.58
IPR001128Cytochrome P450PFAMPF00067p450coord: 37..157
e-value: 9.9E-17
score: 60.8
IPR001128Cytochrome P450PRINTSPR00385P450coord: 292..303
score: 51.96
coord: 150..167
score: 42.43
coord: 203..214
score: 32.39
coord: 283..292
score: 57.16
IPR001128Cytochrome P450PFAMPF00067p450coord: 3..319
e-value: 5.4E-78
score: 262.8
IPR036396Cytochrome P450 superfamilyGENE3DG3DSA:1.10.630.10coord: 30..159
e-value: 9.9E-27
score: 95.9
IPR036396Cytochrome P450 superfamilySUPERFAMILYSSF48264Cytochrome P450coord: 38..158
IPR036396Cytochrome P450 superfamilyGENE3DG3DSA:1.10.630.10coord: 1..350
e-value: 4.1E-91
score: 308.2
IPR036396Cytochrome P450 superfamilySUPERFAMILYSSF48264Cytochrome P450coord: 4..326
NoneNo IPR availablePANTHERPTHR24300FAMILY NOT NAMEDcoord: 9..158
NoneNo IPR availablePANTHERPTHR24300:SF302coord: 9..158
NoneNo IPR availableTMHMMTMhelixcoord: 4..21
NoneNo IPR availablePANTHERPTHR24300FAMILY NOT NAMEDcoord: 13..340
IPR017972Cytochrome P450, conserved sitePROSITEPS00086CYTOCHROME_P450coord: 285..294