PKD2-3
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035484 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 15
Homology
BLAST of PKD2-3 vs. Ensembl Human
Match: PKD2 (polycystin 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9009]) HSP 1 Score: 392.119 bits (1006), Expect = 2.237e-121 Identity = 252/704 (35.80%), Postives = 414/704 (58.81%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGN---LMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKK-------KISEAMNSEKDGSFKRQNSKSQINLRESDSN-------AIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR ++ + +N + Y+ + LREL YL+FL++L ++++G +++N +Y+ M F++ + F LS+ +W++ + L L+W +P TE + +++E L+GV R+RQ+R + C +P L CY+ YS+ ++D AP P ++ W YTS + +++G I+ Y G GY +DL+ +T V+ LK+ W+DRGTRA F+DF V+N N+NLFC VR++ EFP GGV+ S+ P KL+RY + F++F+ CEI+F FI YY +E ILE R K F+++W+ D+V+V++S++ I NIYR V + + + +T+P F+ ++ + F + ++ +F +K+FK+I FN+TM+ LS+T+ R K++FGF++MF I+F+A+AQLAYL+FG+ D+S Q + +QFRIILGD ++ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + +S+ + + + K+K + DI +++ G L FDE R +K KG+ D EIEA+F+KYD DGDQ L +E +QM + LE E++ + M+S SF R S+ + E + V+ EE L R+D +E+++ I+ KID V+ +E +E KL ++V+G++L+ Sbjct: 200 LWGTRL-MEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDT--PVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYW-----KMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP-RNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNV-EVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSR---SFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLD 886
BLAST of PKD2-3 vs. Ensembl Human
Match: PKD2L1 (polycystin 2 like 1, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9011]) HSP 1 Score: 382.489 bits (981), Expect = 2.279e-119 Identity = 246/689 (35.70%), Postives = 403/689 (58.49%), Query Frame = 3 Query: 339 NSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEI---EAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIE 2396 +S C +C+ I LW T T + N ++YI TTLREL +Y++FLV + L+++G +++++Y+ M F++ D G + F +S+ +W++ L L+W W N++ + +Y+E L+GV R+RQ++ + C + CY+ YS ++ P P WTY S +++G ++ Y GGGY +DL + + + L+E W+DRGTR VF+DF V+N N+NLFC +R+V EFP GG + S+ I KL+RY S +++FI+ CE++F +FI YY +E ILE + + + W+I D+VV+L+SI+ + F+I+R + VN+ + ++ +TY F+ ++ + + + ++NLF A +KIFKYI FNKTMT LSSTL R K+I GF+VMF IVF A+AQL YL+FG+ ++S + +QFRIILGDFDY A+ AN G YFV YVFFVFFVL+NMF+AII + Y +VK + + +S+ K + R +++ +++ D+Q + G+ + F+++ T+++ G+A+ EI A F+K+D DG+++LD EQ++M + LE E+ A+N+E + + S Q + A +V+ EE L R+ LE ++ ++ +ID V S ++ +E Sbjct: 67 SSCCLHICQGIRG-LWGT-TLTENTAENRELYIKTTLRELLVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDTG----VSFQAISSMADFWDFAQGPLLDSLYWT-KWYNNQSLGHGSHSFIYYENMLLGVPRLRQLKVRNDSCVVHEDFREDILSCYDVYSPDKEEQLPFGPFNGT-AWTYHSQDELGGFSHWGRLTSYSGGGYYLDLPGSRQGSAEALRALQEGLWLDRGTRVVFIDFSVYNANINLFCVLRLVVEFPATGGAIPSWQIRTVKLIRYVSNWDFFIVGCEVIFCVFIFYYVVEEILELHIHRLRYLSSIWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPNTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAVMFFIVFFAYAQLGYLLFGTQVENFSTFIKCIFTQFRIILGDFDYNAIDNANRILGPAYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQE----IQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKEQEKMRQDLEEERV----ALNTEIEKLGRSIVSSPQGKSGPEAARAGGWVSGEEFYMLTRRVLQLETVLEGVVSQIDAVGSKLKMLE 739
BLAST of PKD2-3 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]) HSP 1 Score: 271.166 bits (692), Expect = 1.445e-79 Identity = 189/539 (35.06%), Postives = 317/539 (58.81%), Query Frame = 3 Query: 426 DIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQT-ISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYL-GFDE 2036 ++ I TTL+EL +Y IFL+ L +++FG +N + +Y M + F++ + F + + +W++++ L+ L+WD + N + + +Y+E L+GV R+RQ++ + C++ S S CY KY+ N+D + + N W Y++S + ++ GG S S N+ + DL+ +WI RGTR +F+DF ++N N+NLFC +R+VAEFP GG++TS+ KLLRY S ++YFI CEI F IF+ + + + + +E K FK+ W+ +++++L+ + +SFN Y + + + ++ S + Y F ++ + + + I+I +F A +KIFK+I FNKTM+ LSSTL R K+I GF++MF I+F A+AQL +L+FGS D+S Q S+ +QFRI+LGDF++ + +AN G IYF+ ++FFVFFVL+NMF+AII + Y +VK D +I + + + K V+E+F++K + + + +GDL + GFDE Sbjct: 22 EVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVP--GEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGL-QINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFI-DLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDE 556
BLAST of PKD2-3 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]) HSP 1 Score: 270.781 bits (691), Expect = 1.490e-79 Identity = 189/539 (35.06%), Postives = 317/539 (58.81%), Query Frame = 3 Query: 426 DIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQT-ISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYL-GFDE 2036 ++ I TTL+EL +Y IFL+ L +++FG +N + +Y M + F++ + F + + +W++++ L+ L+WD + N + + +Y+E L+GV R+RQ++ + C++ S S CY KY+ N+D + + N W Y++S + ++ GG S S N+ + DL+ +WI RGTR +F+DF ++N N+NLFC +R+VAEFP GG++TS+ KLLRY S ++YFI CEI F IF+ + + + + +E K FK+ W+ +++++L+ + +SFN Y + + + ++ S + Y F ++ + + + I+I +F A +KIFK+I FNKTM+ LSSTL R K+I GF++MF I+F A+AQL +L+FGS D+S Q S+ +QFRI+LGDF++ + +AN G IYF+ ++FFVFFVL+NMF+AII + Y +VK D +I + + + K V+E+F++K + + + +GDL + GFDE Sbjct: 22 EVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVP--GEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGL-QINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFI-DLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWNWLELLLLLLCFVAVSFNTYYNVQIFLLLGQLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDE 556
BLAST of PKD2-3 vs. Ensembl Human
Match: PKD2L2 (polycystin 2 like 2, transient receptor potential cation channel [Source:HGNC Symbol;Acc:HGNC:9012]) HSP 1 Score: 253.062 bits (645), Expect = 4.391e-73 Identity = 184/539 (34.14%), Postives = 304/539 (56.40%), Query Frame = 3 Query: 426 DIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQT-ISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYL-GFDE 2036 ++ I TTL+EL +Y IFL+ L +++FG +N + +Y M + F++ + F + + +W++++ L+ L+WD + N + + +Y+E L+GV R+RQ++ + C++ S S CY KY+ N+D + + N W Y++S + ++ GG S S N+ + DL+ +WI RGTR +F+DF ++N N+NLFC +R+VAEFP GG++TS+ KLLRY S ++YFI CEI F IF+ + + + + +E K FK+ W+ ++ + ++ S + Y F ++ + + + I+I +F A +KIFK+I FNKTM+ LSSTL R K+I GF++MF I+F A+AQL +L+FGS D+S Q S+ +QFRI+LGDF++ + +AN G IYF+ ++FFVFFVL+NMF+AII + Y +VK D +I + + + K V+E+F++K + + + +GDL + GFDE Sbjct: 22 EVEITTTLQELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFLDTSVP--GEERTNFKSIRSITDFWKFMEGPLLEGLYWDSWYNNQQLYNLKNSSRIYYENILLGVPRVRQLKVRNNTCKVYSSFQSLMSECYGKYTSANEDLSNFGL-QINTEWRYSTSNTNSPWHWGFLGVYRNGGYIFTLSKSKSETKNKFI-DLRLNSWITRGTRVIFIDFSLYNANVNLFCIIRLVAEFPATGGILTSWQFYSVKLLRYVSYYDYFIASCEITFCIFLFVFTTQEVKKIKEFKSAYFKSIWN----------------------WLELLLLLLLKSTEKYSDFYFLACWHIYYNNIIAITIFFAWIKIFKFISFNKTMSQLSSTLSRCVKDIVGFAIMFFIIFFAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANPILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRLDFELGKMIKQSYKNVLEKFRLKKAQKDEDKKTKGSGDLAEQARREGFDE 534
BLAST of PKD2-3 vs. Ensembl Celegans
Match: pkd-2 (Polycystin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9U1S7]) HSP 1 Score: 205.297 bits (521), Expect = 1.323e-55 Identity = 174/633 (27.49%), Postives = 318/633 (50.24%), Query Frame = 3 Query: 522 SFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTY-TSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQ 2417 S+Y++ M + F+ G F ++ W++L V + ++W ++ ++ E N++Y+E +L+G R+R ++ C + C+ Y +D M + S + Y T+ ++ S GGG + S + ++ LK WIDRG+RA+ +DF ++N N+NLFC V+++ E P GGV+T+ + LL Y ++ ++ E +F FI+Y+ E + + +W++ D+V++ S+ I ++ R ++++VI + T FD ++ + + + + +F+A +K+FK+I NKTM+ LSSTL RS K+I GF+VMF + F AFAQ YL FG+ DYS + S + R+ILGDF++ AL N FG +F+ YVFFV F+L+NMF+AII ++YV+VK + + ++F +K + +R K + +DA +++++L + + GYA+ +I F++++V M E + +K++E + E + E N +E + LN R+D ++ +V I+ +I+ V +++++IE Q++ Q Sbjct: 99 SYYYSKVMSDLFVAST---GASGAPAFGSCTSMDNIWDWLSQVLIPGIYWTETSNSTDNE-----NMIYYENRLLGEPRIRMLKVTNDSCTVMKSFQREIKECFANYEEKLEDKT-MVGDGSVDAFIYATAKELENLKTVGTIASYGGGGFVQRLPVAGSTEAQSAIATLKANRWIDRGSRAIIVDFALYNANINLFCVVKLLFELPASGGVITTPKLMTYDLLTYQTSGGTRMMIFEGIFCGFILYFIFEELFAIGRHRLHYLTQFWNLVDVVLLGFSVATIILSVNRTKTGVNRVNSVIENGLTNAPFDDVTSSENSYLNIKACVVFVAWVKVFKFISVNKTMSQLSSTLTRSAKDIGGFAVMFAVFFFAFAQFGYLCFGTQIADYSNLYNSAFALLRLILGDFNFSALESCNRFFGPAFFIAYVFFVSFILLNMFLAIINDSYVEVKAELARKKDGEGILDWFMNKVRGLTKRGK---RPDAPGEDAT------------YEDYKLMLYRAGYAEKDINEAFTRFNV-----------TSMTEHV---PEKVAEDIADE------------VARMTEQKRNYME--NHRDYANLNRRVDQMQESVFSIVDRIEGVNATLQTIEKQRVQQQ 679
BLAST of PKD2-3 vs. Ensembl Celegans
Match: lov-1 (Location of vulva defective 1 [Source:UniProtKB/Swiss-Prot;Acc:Q09624]) HSP 1 Score: 72.4034 bits (176), Expect = 1.355e-12 Identity = 101/502 (20.12%), Postives = 212/502 (42.23%), Query Frame = 3 Query: 582 NLKDLQFPDLSNTRQYWEYL-DNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSK-VIPCQMPSYLLSRNFPCYEKYSIFNDDS-----APMRPNKSNPG------WTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSA--------------FEYFILCCEILFVIFIIYYAIEVILEFR---EIKWQI-FKNY--WSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSD-DTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQD 1985 N D F + + +W++ +++A L SW + P + + +G+ +RQVR+K C M C E+ + N++ A +S G +TY +S+ + G + Y GGGY I ++ + + + L + WID TRAV ++F +N +N F V+++ E P G + + + +L++ + F I EI+F ++ Y I + R +I +Q+ N+ W+ D++V +++ + R N+ + ++ ++Y + ++ +F + ++ +F K+ + +RFN+ + L++TL + I F + FL + F + Y + G+ Y + + + +LG D ++ + F + +LY+ +++ ++V II + ++++D + + K KT + + K V I D Sbjct: 2718 NYGDNTFMSIQHADDFWDWARESLATALL---ASWYDGNPAYGMRAYMNDKVSRSMGIGTIRQVRTKKSAECTMFKQFQGYINDCGEELTSKNEEKTLYMQAGWTELESENGTDASDEYTYKTSEELSTETVSGLLYSYSGGGYTISMSGTQAEIITLFNKLDSERWIDDHTRAVIIEFSAYNAQINYFSVVQLLVEIPKSGIYLPNSWVESVRLIKSEGSDGTVVKYYEMLYIFFSVLIFVKEIVFYLYGRYKVITTMKPTRNPFKIVYQLALGNFSPWNFMDLIVGALAVASVLAYTIRQRTTNRAMEDFNANNGNSYINLTEQRNWEIVFSYCLAGAVFFTSCKMIRILRFNRRIGVLAATLDNALGAIVSFGIAFLFFSMTFNSVLYAVLGNKMGGYRSLMATFQTALAGMLGKLDVTSIQPIS-QFAFVVIMLYMIAGSKLVLQLYVTIIMFEFEEIRNDSEKQTNDYEIIDHIKYKTKRRLGLLEPKDFAPVSIAD 3215
BLAST of PKD2-3 vs. Ensembl Fly
Match: Pkd2 (gene:FBgn0041195 transcript:FBtr0080365) HSP 1 Score: 192.2 bits (487), Expect = 2.474e-50 Identity = 130/400 (32.50%), Postives = 212/400 (53.00%), Query Frame = 3 Query: 711 EGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNK---------SNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQI-FKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDET 1880 EG + +E L+G R+RQ+R + C + + CY YS +D PM S P WT + + Y ++L D ++ +I++DLK+ W+DRG+R ++F +FN N ++F ++++AE P GGV+ + K+ + + + I + I +IYY I I E R+ +I F + +I D ++L + + +NI+ V ++ SD TY D + ++ ++ ++I F+ +KIFK+I FNKT+ ++TL R K++ GFS+MF IVF+A+AQL L+FG+ D+ TS+L+ R+ILGDF Y + +AN G IYF+ Y+ VFF+L+NMF+AII E Y VK + T Sbjct: 424 EGRVFLYENLLLGPPRLRQIRVRKESCYVNDAFIRYFNTCYAAYSSGAEDRKPMHKGSPFRTMHDLDSTPIWTVLAFYRTGG--------------YTVNLDYDKDRNVKIINDLKDIHWLDRGSRLCLVEFNLFNENTDIFQSIKLIAEIPPTGGVIPQAHLQTVKMYSFFTDRSMLMTVIYIFWYIMVIYYTIYEITEIRKSGIKIYFCSMLNILDCAILLGCYLALVYNIWHSFKV-MSLTARAHSDVTYQSLDVLCFWNIIYVDMMAILAFLVWIKIFKFISFNKTLVQFTTTLKRCSKDLAGFSLMFGIVFLAYAQLGLLLFGTKHPDFRNFITSILTMIRMILGDFQYNLIEQANRVLGPIYFLTYILLVFFILLNMFLAIIMETYNTVKGEIT 808
BLAST of PKD2-3 vs. Ensembl Fly
Match: brv2 (gene:FBgn0036712 transcript:FBtr0331846) HSP 1 Score: 62.7734 bits (151), Expect = 1.187e-9 Identity = 55/242 (22.73%), Postives = 110/242 (45.45%), Query Frame = 3 Query: 1026 LKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLL-----RYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKN------YWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLF---IAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLS 1709 L++ +W+D+ T A+F+D ++N + NLF + + E FG + + +L R +S L ++F+ Y + VIL R + +I+ + W++ D+ + ++++ I R I + + I+ T Q+ + RL Q + F I L+++K ++F H + TL + + + V+ L+V +A + G+NA +S M SV++ Sbjct: 292 LRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSE----------LLILFV--YTVLVILFARGVFTKIWHHPAAAHEAWTMVDLAIYILNVFLTVLAIMRDIETDALLQ--IIETATKGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIGITLAVPNGNNAVVFSHMVQSVVT 519
BLAST of PKD2-3 vs. Ensembl Fly
Match: brv2 (gene:FBgn0036712 transcript:FBtr0075242) HSP 1 Score: 62.003 bits (149), Expect = 1.998e-9 Identity = 55/242 (22.73%), Postives = 110/242 (45.45%), Query Frame = 3 Query: 1026 LKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLL-----RYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKN------YWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLF---IAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLS 1709 L++ +W+D+ T A+F+D ++N + NLF + + E FG + + +L R +S L ++F+ Y + VIL R + +I+ + W++ D+ + ++++ I R I + + I+ T Q+ + RL Q + F I L+++K ++F H + TL + + + V+ L+V +A + G+NA +S M SV++ Sbjct: 314 LRDYSWLDKNTSALFIDLTMYNADANLFTLITLRVENSPFGIQLPRVHVDSVSMLGNVETRSNSE----------LLILFV--YTVLVILFARGVFTKIWHHPAAAHEAWTMVDLAIYILNVFLTVLAIMRDIETDALLQ--IIETATKGQYLDFQRPLRLHQMLFIVKGFLVCITTLRLWKVLQFASVFQHFTQTLFSAWRAVASLGVIILVVLMAIGITLAVPNGNNAVVFSHMVQSVVT 541
BLAST of PKD2-3 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0340092) HSP 1 Score: 58.9214 bits (141), Expect = 1.740e-8 Identity = 91/428 (21.26%), Postives = 186/428 (43.46%), Query Frame = 3 Query: 741 LVGVARMRQVRSK-----VIPCQ------MPSYLLS-RNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKW---QIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTV-IVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKA------LSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVK--HDETINNQTISMSEFFKSKTAAVMERFK 1952 L+GV R+RQ+R + P + MP + L R +KY + P++ G+ + + + D+ S GY+ L + + +++ L E W+ T AVF+DF ++N+++NLF + E FGG+V + +KLL Y L +++V+ I +A + ++ W + K+ W+ D+ + +V+++ + + R V + V S + F + S+ +L I + I L++++ ++F + TL + + ++ +I I F + G+ +++++ + V S + F + A L G + + + F + +LIN+FV++I + + K D N+ I+ EF + + V+ RF+ Sbjct: 213 LLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKM-----GFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKL----WYEPHLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYSSNFNKL---VKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVIIVLLINVFVSLINDYFTVAKTIRDSERENR-ITFFEFLVVEFSGVLGRFR 627
BLAST of PKD2-3 vs. Ensembl Fly
Match: brv3 (gene:FBgn0040333 transcript:FBtr0300708) HSP 1 Score: 58.9214 bits (141), Expect = 1.939e-8 Identity = 92/427 (21.55%), Postives = 186/427 (43.56%), Query Frame = 3 Query: 741 LVGVARMRQVRSK-----VIPCQ------MPSYLLS-RNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYA--IEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTV-IVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKA------LSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVK--HDETINNQTISMSEFFKSKTAAVMERFK 1952 L+GV R+RQ+R + P + MP + L R +KY + P++ G+ + + + D+ S GY+ L + + +++ L E W+ T AVF+DF ++N+++NLF + E FGG+V + +KLL Y L +++V+ I +A + V L + + K+ W+ D+ + +V+++ + + R V + V S + F + S+ +L I + I L++++ ++F + TL + + ++ +I I F + G+ +++++ + V S + F + A L G + + + F + +LIN+FV++I + + K D N+ I+ EF + + V+ RF+ Sbjct: 213 LLGVMRLRQLRVSNPQVGLGPPKFSDTYYMPDWQLPYRKLHYSDKYWRIYEPWIPIKM-----GFEFLDALLMNFDHVGSLNSYPELAGYVSLLARSAANSMKVIDYLSENHWLTLNTSAVFIDFTLYNVDVNLFSICTLRVEKTPFGGIVPDVQVDSAKLLENVDQMPYTGLLALLIYVLVFIQFAQTLAVKLWYEP---HLLKSVWNKLDLFIFMVNVLVVVLVVLRESLVASMMKKVEGASKMEFIDFRRPSRMHQLTTITIGFLICITTLRLWRVLQFASVFKLFTRTLYLAWSAVASTAIAIVIFLIGFCFAVVTINGNYSSNFNKL---VKSMVMCMCYSFGFSAQVKPSELFHGGKWLGILCYGVLAFVIIVLLINVFVSLINDYFTVAKTIRDSERENR-ITFFEFLVVEFSGVLGRFR 627
BLAST of PKD2-3 vs. Ensembl Zebrafish
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387]) HSP 1 Score: 417.927 bits (1073), Expect = 5.598e-132 Identity = 257/716 (35.89%), Postives = 418/716 (58.38%), Query Frame = 3 Query: 333 KQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSR--PETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQ-----------EELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 +++ C + + LW TR + N SN ++Y+ T LRE+ Y++FL+ L +I++G ++ N +Y+ M F++ G + F LS +W++ + L ++W+ W N++ PE + L+Y+E L+GV R+RQ+R + C + L + CY YS N+D AP P K+ W + +Y+G +S YGGGGY DL+ K+ + +LK W+DRGTRAVFLDF ++N N+NLFC VR++ EFP GG V S+ +LLRY S+++YF+ CE+ F +F++YY +E LE R + + FK+ W+ D+++V +S+ I NI R V+ ++ ++ + TYP F+ +++ F + +I +F++ +K+FK+I FNKTM LS+T+ R K++ GF++MF IVF+A+AQLAYL+FG+ D+S Q + +QFRIILGDFD+ + EA+ G IYF +VFF+F +L+NMF+AII + Y +VK D + +++ K M + K+K I DI D++ L FDE R ++ KG++D EIEA+F+KYD+DGDQ L +E +QM + LE E++ + +S + R S+SQ + E D + ++ EE L R+D +E+++ I+ KID V+ +E++E K+ + V+G+IL+ Sbjct: 120 QEHRSCGKRILEKMRVLWDTRLLGESN-SNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSG--EPTNFKSLSTMEDFWKFTEGPFLNGMYWE-LWYNNKSLPENQS---LIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGP-KNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILD 823
BLAST of PKD2-3 vs. Ensembl Zebrafish
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 402.134 bits (1032), Expect = 3.576e-127 Identity = 255/698 (36.53%), Postives = 405/698 (58.02%), Query Frame = 3 Query: 327 DEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFN-DDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQ 2417 +E + S C + LW T + D K N ++ + L+EL IY++FLV L L+++G ++ ++Y+ AM + F+N G + F + W Y++ L L+W W N P + + +Y+E L+GV R+RQ++ K C++P+ C++ Y+I DD A N + W Y S + + +++G ++ Y G G+ DLT+ +++ ++ DL+E W+DRGTR +F+DF +N N+NLFC +R+V EFP GG + S+ I KL+RY + ++YFI+ CEI+F +FI+YY +E ILEFR K F + W+I D+VV+L++++ I F+ +R I V+ + ++ D Y F+ ++ + + + ++NLF A +KIFKYI FNKTMT L+STL R +IFGF++MF IVF A+AQL YL+FG+ +S + +QFRIILGDFDY A+ AN G IYF YVFFVFFVL+NMF+AII + Y +VK + +++ K A + K+K +KI D+Q A+++G S L F ++R +K+ G++D EI A FSK+D DG+Q LD EQ+ M ++LE ++ +S + ++ ++ + E N V E+ L ++ LEN+V I+ K+D V ME + LQ N + Sbjct: 54 NEDKKSGCCSFFFRAIKGLWGTALRKD-TKENPELNVKANLKELLIYIVFLVDLCLLTYGMTSSATYYYTKAMTDLFVNLPGSNG----MSFSSIGCMNDVWTYMEGPLLDNLYWT-KWYNDEPLENGNQSFIYYENLLLGVPRVRQLKVKQNSCKVPTDFKKEISDCFDVYNIKKEDDGAFGLINGT--AWQYHSEKEIKGSSHWGLLTTYSGAGFYQDLTTTRDESAALLEDLRENLWLDRGTRVLFIDFTAYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYVTTWDYFIIGCEIVFCVFILYYIVEEILEFRIHKLSHFTSIWNILDIVVILLAVVAIVFSAFRTIKVDGLLGNLLKQPDIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLTSTLARCALDIFGFAIMFFIVFFAYAQLGYLLFGTEVETFSTFNKCIFTQFRIILGDFDYDAIDRANRVLGPIYFFSYVFFVFFVLLNMFLAIINDTYSEVKSELASQKDEFQIADLIKQSYAKTFMKLKLKKEKISDVQKALDSG----ASELEFKDFRNALKEMGHSDREISAAFSKFDQDGNQTLDKQEQENMKQELEEKRDALSAEL----------RDLENSVEPAEEHRNT---VPPEDYQRLVHKVSQLENSVSAIMSKLDFV---MEKMRLQTFNTE 723
BLAST of PKD2-3 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89]) HSP 1 Score: 151.369 bits (381), Expect = 5.824e-37 Identity = 110/394 (27.92%), Postives = 204/394 (51.78%), Query Frame = 3 Query: 696 PETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRP--------NKSNP---GWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAII 1844 P T+GN KLVG AR+RQVR + C++ + + C+ YS ++D P N S W Y + +A+ +G ++LY GGG+++DL D ++++ L + TW+D TRAVF++F V+N N+NLFC V ++ E G + L + + F F++ E ++ IFI+YY + ++ KW FK+ W++ ++ ++++S +S + R I N+ I + D + F++ + D + + I+ + +A +K++ +R N + ++STL R+ +I GF V+ I+F+A++ LM+G Y + + + + LG F+Y + + N GA + F+ FV++N+F+++I Sbjct: 683 PGFITDGN-----SKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVI 1071
BLAST of PKD2-3 vs. Ensembl Zebrafish
Match: pkd1l2a (polycystic kidney disease 1 like 2a [Source:ZFIN;Acc:ZDB-GENE-050208-89]) HSP 1 Score: 150.214 bits (378), Expect = 2.555e-36 Identity = 110/394 (27.92%), Postives = 204/394 (51.78%), Query Frame = 3 Query: 696 PETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRP--------NKSNP---GWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAII 1844 P T+GN KLVG AR+RQVR + C++ + + C+ YS ++D P N S W Y + +A+ +G ++LY GGG+++DL D ++++ L + TW+D TRAVF++F V+N N+NLFC V ++ E G + L + + F F++ E ++ IFI+YY + ++ KW FK+ W++ ++ ++++S +S + R I N+ I + D + F++ + D + + I+ + +A +K++ +R N + ++STL R+ +I GF V+ I+F+A++ LM+G Y + + + + LG F+Y + + N GA + F+ FV++N+F+++I Sbjct: 2043 PGFITDGN-----SKLVGNARIRQVRVRRDTCKIANPMQYSVRDCHAPYSWESEDMGSYSPGWNQTRNVNGSKTVLKPWYYQTQAKLRANPVWGGLALYKGGGFVVDLGPDQKNASRLLQYLFDNTWLDVYTRAVFVEFTVYNANVNLFCIVTLIFETTGVGTFQYRSEVQAVHLYQSTGGFHVFVMASEAIYYIFILYYMVVQGKLMKQQKWAYFKSKWNLLELAIIILSWSALSVFVKRTILGNRDIEFYQNNKDMFVSFNETATADAVLGYLIAFLVLLATIKLWHLLRLNPKLHMITSTLQRAWTDISGFIVVMTIMFLAYSIACNLMYGWRLNSYRTLLEAAQTIICLQLGIFNYDEVLDYNPVLGAFLIGSCIIFMTFVVLNLFISVI 2431
BLAST of PKD2-3 vs. Ensembl Zebrafish
Match: pkd1l2b (polycystic kidney disease 1 like 2b [Source:ZFIN;Acc:ZDB-GENE-141222-87]) HSP 1 Score: 146.747 bits (369), Expect = 1.520e-35 Identity = 125/493 (25.35%), Postives = 226/493 (45.84%), Query Frame = 3 Query: 504 GTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRP--------NKSNPG---WTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIIC-------ENYVKVKHDETINNQTISMSEFFKSKT 1928 G + N+FY ++ +F ++G D T + + + V LK LF P T+GN KLVG AR+RQVR K C++ +L C YS N+D P N S G W Y S +A +G +LY GGGY++DL D + L TW+D TRAVF++F V+N N++LFC V ++ E G + L +F F++ +++ +F++YY + KW F+N W++ DM ++++S +S I + + N I + +P F + D ++ ++ + + +K++ +R + + ++S+L R+ ++ +V+ I+ +A++ L+FG Y + + + F + +G F+Y + +N GA+ V FV++++F++II EN+ + +ET+ + + FF K+ Sbjct: 539 GQQDPNAFYLTQHIQQSF-SKGIS----------DSMKTNDVFVWANTVLLKNLF------GQYPGFITDGN-----SKLVGNARIRQVRVKKDTCKVAKVMLHTVSQCNTPYSWGNEDMMSYGPGWEEFNSVNGSEEGITAWQYQSQSTLKALPVWGLTALYRGGGYVMDLGPDKQNATMKLQYLFNSTWLDEYTRAVFVEFTVYNANVDLFCIVTLILESSAVGAFQFRSVLQNVSLYSSVGSFMSFLMASRVIYFLFVVYYMFLQGKLLKRQKWAYFRNKWNLLDMAIIILSWSSLSLFIQKTVQGNIDIQYYQKHKNQFPSFHDTAAVDATLRYVMAFLVLLGCVKLWHLLRLSPKLYVIASSLQRAWDDMSTLTVVIFIILLAYSLACNLIFGWELYTYRTLPDAFTAIFSLQIGIFNYDEVMNSNPALGAVIISSCVLIATFVVLSLFISIILMAVTEERENHQPSEEEETVELVMMKIMSFFGIKS 1009
BLAST of PKD2-3 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674]) HSP 1 Score: 387.111 bits (993), Expect = 2.341e-121 Identity = 245/700 (35.00%), Postives = 397/700 (56.71%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQ--FPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKS-----------QINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR + + + Y+ REL Y++FLV++ ++++ + +N FY+ M F++ KD + F L +W++ + + L+WD W N+R + +Y+E L+GV R+RQ+R K C +P L CY+ YS+ N+D+ P ++ WTYT + + +G IS+Y G GY IDL+ + ++ ++ LK W+DRGTRAVF+DF V+N N+NLFC VR++ EFP GG++TS+ KL+ Y S+FE+F+ CEI+F IFI+YY IE LE F++ W+ D+V++ +S+ I ++Y++ V ++ + + +P + ++ + F ++ +F A +K+FK+ FN+TMT LS+T+ R K+I GF++MF I+F+A+AQ AYL+FG+ D+S Q + +QFRIILGDFD+ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + + + K + M + K+K + DI ++I G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + S R +S + ++ V+ EE L R+D +E+++ I+ KID V+ +E++E KL ++V+G++L+ Sbjct: 15 LWGTRYT-EERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVS----KDERTNFKTLLTMDDFWKFTEGPLMDGLYWD-MWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPFGL-RNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 702
BLAST of PKD2-3 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674]) HSP 1 Score: 385.956 bits (990), Expect = 4.709e-121 Identity = 233/657 (35.46%), Postives = 373/657 (56.77%), Query Frame = 3 Query: 510 INANSFYFAAAMENAFINEGFDFGNLKDLQ--FPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKS-----------QINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 + +N FY+ M F++ KD + F L +W++ + + L+WD W N+R + +Y+E L+GV R+RQ+R K C +P L CY+ YS+ N+D+ P ++ WTYT + + +G IS+Y G GY IDL+ + ++ ++ LK W+DRGTRAVF+DF V+N N+NLFC VR++ EFP GG++TS+ KL+ Y S+FE+F+ CEI+F IFI+YY IE LE F++ W+ D+V++ +S+ I ++Y++ V ++ + + +P + ++ + F ++ +F A +K+FK+ FN+TMT LS+T+ R K+I GF++MF I+F+A+AQ AYL+FG+ D+S Q + +QFRIILGDFD+ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + + + K + M + K+K + DI ++I G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + S R +S + ++ V+ EE L R+D +E+++ I+ KID V+ +E++E KL ++V+G++L+ Sbjct: 70 VTSNMFYYTKGMSQLFLDGPVS----KDERTNFKTLLTMDDFWKFTEGPLMDGLYWD-MWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPF-GLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 715
BLAST of PKD2-3 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674]) HSP 1 Score: 386.726 bits (992), Expect = 8.148e-121 Identity = 247/714 (34.59%), Postives = 404/714 (56.58%), Query Frame = 3 Query: 339 NSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQ--FPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKS-----------QINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 +++ + + T LW TR + + + Y+ REL Y++FLV++ ++++ + +N FY+ M F++ KD + F L +W++ + + L+WD W N+R + +Y+E L+GV R+RQ+R K C +P L CY+ YS+ N+D+ P ++ WTYT + + +G IS+Y G GY IDL+ + ++ ++ LK W+DRGTRAVF+DF V+N N+NLFC VR++ EFP GG++TS+ KL+ Y S+FE+F+ CEI+F IFI+YY IE LE F++ W+ D+V++ +S+ I ++Y++ V ++ + + +P + ++ + F ++ +F A +K+FK+ FN+TMT LS+T+ R K+I GF++MF I+F+A+AQ AYL+FG+ D+S Q + +QFRIILGDFD+ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + + + K K + M + K+K + DI ++I G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + S R +S + ++ V+ EE L R+D +E+++ I+ KID V+ +E++E KL ++V+G++L+ Sbjct: 39 HAQAREAGRRETRRLWGTRY-TEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVS----KDERTNFKTLLTMDDFWKFTEGPLMDGLYWD-MWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPF-GLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIK-KVSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 739
BLAST of PKD2-3 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674]) HSP 1 Score: 387.882 bits (995), Expect = 4.174e-120 Identity = 247/724 (34.12%), Postives = 407/724 (56.22%), Query Frame = 3 Query: 309 NDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQ--FPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKS-----------QINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 N + D+ + + + + ++ LW TR + + + Y+ REL Y++FLV++ ++++ + +N FY+ M F++ KD + F L +W++ + + L+WD W N+R + +Y+E L+GV R+RQ+R K C +P L CY+ YS+ N+D+ P ++ WTYT + + +G IS+Y G GY IDL+ + ++ ++ LK W+DRGTRAVF+DF V+N N+NLFC VR++ EFP GG++TS+ KL+ Y S+FE+F+ CEI+F IFI+YY IE LE F++ W+ D+V++ +S+ I ++Y++ V ++ + + +P + ++ + F ++ +F A +K+FK+ FN+TMT LS+T+ R K+I GF++MF I+F+A+AQ AYL+FG+ D+S Q + +QFRIILGDFD+ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + + + K + M + K+K + DI ++I G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + S R +S + ++ V+ EE L R+D +E+++ I+ KID V+ +E++E KL ++V+G++L+ Sbjct: 154 NGLVACDKPSLAWATNLLDMPSHRLWGTRY-TEERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVS----KDERTNFKTLLTMDDFWKFTEGPLMDGLYWD-MWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPF-GLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 865
BLAST of PKD2-3 vs. Ensembl Xenopus
Match: usp33 (ubiquitin specific peptidase 33 [Source:Xenbase;Acc:XB-GENE-1016674]) HSP 1 Score: 385.571 bits (989), Expect = 4.367e-119 Identity = 245/700 (35.00%), Postives = 397/700 (56.71%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQ--FPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKS-----------QINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR + + + Y+ REL Y++FLV++ ++++ + +N FY+ M F++ KD + F L +W++ + + L+WD W N+R + +Y+E L+GV R+RQ+R K C +P L CY+ YS+ N+D+ P ++ WTYT + + +G IS+Y G GY IDL+ + ++ ++ LK W+DRGTRAVF+DF V+N N+NLFC VR++ EFP GG++TS+ KL+ Y S+FE+F+ CEI+F IFI+YY IE LE F++ W+ D+V++ +S+ I ++Y++ V ++ + + +P + ++ + F ++ +F A +K+FK+ FN+TMT LS+T+ R K+I GF++MF I+F+A+AQ AYL+FG+ D+S Q + +QFRIILGDFD+ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + + + K + M + K+K + DI ++I G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + S R +S + ++ V+ EE L R+D +E+++ I+ KID V+ +E++E KL ++V+G++L+ Sbjct: 181 LWGTRYT-EERITTREKYLKIVFRELITYIVFLVIVCVLTYSMVTSNMFYYTKGMSQLFLDGPVS----KDERTNFKTLLTMDDFWKFTEGPLMDGLYWD-MWYNNRTMAENH-SFIYYENLLLGVPRLRQLRVKNGSCSVPEDLKDEIKDCYDSYSVRNEDTTPF-GLRNGTAWTYTKEKDLNGSSQWGVISVYSGAGYYIDLSRNREESAAQIAMLKNNLWLDRGTRAVFIDFSVYNANLNLFCVVRLLVEFPATGGLITSWQFQTVKLIHYISSFEFFLAACEIIFCIFILYYIIEEFLEIHVHHLHYFRSLWNWLDIVIIGLSLPAIGIHLYKMSSVEGPLNKQLSDLNVFPNLESLAYWQIQFNSVAAVIVFFAWVKLFKFANFNRTMTQLSTTMSRCAKDILGFAIMFFIIFLAYAQFAYLVFGTQIDDFSTFQHCIFTQFRIILGDFDFTEVEEANRILGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKTDMAQQKSEMELIDLIKKGCSKAMVKLKLKKTTVDDISESIRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFAKYDQDGDQELTENEHQQMRDDLEKEREDLEMDRGSLPRPMSGRSFPRSLDDSEEDDDEDSGHSSRRRGSSSSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 868
BLAST of PKD2-3 vs. Ensembl Mouse
Match: Pkd2l1 (polycystic kidney disease 2-like 1 [Source:MGI Symbol;Acc:MGI:1352448]) HSP 1 Score: 389.808 bits (1000), Expect = 8.943e-123 Identity = 242/686 (35.28%), Postives = 400/686 (58.31%), Query Frame = 3 Query: 339 NSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIE 2396 +S C +C I LW T T + N ++Y+ TTLREL +Y++FLV + L+++G +++++Y+ M F++ D G + F +S+ +W++ L L+W W N++ + +Y+E L+G R+RQ+R + C + CY+ YS +D P P ++ WTY S +++G ++ Y GGGY +DL + + + L+E W+DRGTR VF+DF V+N N+NLFC +R+V EFP GG + S+ I KL+RY + +++FI+ CE++F +FI YY +E ILE + + + W+I D+VV+L+SI+ + F+I+R + VN+ + ++ DTY F+ ++ + + + ++NLF A +KIFKYI FNKTMT LSSTL R K+I GF++MF IVF A+AQL YL+FG+ ++S + +QFRIILGDFDY A+ AN G +YFV YVFFVFFVL+NMF+AII + Y +VK + + +S+F K + R +++ +++ D+Q + G + + F+++ T+++ G+ + EI A F+++D DGD +LD EQ+QM + LE E+ +N+E + + L + +V+ EE L R+ L+ ++ ++ +ID V S ++ +E Sbjct: 67 SSCCLHICRSIRG-LWGT-TLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDSG----VSFQTISSMSDFWDFAQGPLLDSLYWT-KWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGP-QNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGG----EPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERV----TLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLE 736
BLAST of PKD2-3 vs. Ensembl Mouse
Match: Pkd2 (polycystin 2, transient receptor potential cation channel [Source:MGI Symbol;Acc:MGI:1099818]) HSP 1 Score: 389.808 bits (1000), Expect = 1.246e-120 Identity = 246/698 (35.24%), Postives = 410/698 (58.74%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEY-----------VTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR + N +N + Y+ + LREL YL FLV+L ++++G +++N +Y+ + FI+ + F LS+ +W++ + L L+W N + + +++E L+GV R+RQ+R + C +P L CY+ YS+ ++D AP P ++ W YTS + +++G I+ Y G GY +DL+ +T ++ L+ W+DRGTRA F+DF V+N N+NLFC VR++AEFP GGVV S+ P KL+RY +AF++F+ CEI+F FIIYY +E ILE R + F+++W+ D+V+V++S++ + NIYR+ + + + +++P F+ ++ + F + ++ +F+ +K+FK+I FN+TM+ LS+T+ R K++FGF++MF I+F+A+AQLAYL+FG+ D+S Q + +QFRIILGD ++ + EAN G +YF +VFF+FF+L+NMF+AII ++Y +VK D + +S+ + + + K+K + I +++ G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + +S R +S + E D + V+ EE L R+D +E+++ I+ KID V+ +E +E KL ++V+G++L+ Sbjct: 198 LWGTRLMEESN-ANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDT--PVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSNH--TQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP-RNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNA-EGLLQFLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTVDAISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLD 884
BLAST of PKD2-3 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231]) HSP 1 Score: 280.411 bits (716), Expect = 4.022e-83 Identity = 186/523 (35.56%), Postives = 317/523 (60.61%), Query Frame = 3 Query: 408 GNKSNADIY------IMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQT-ISMSEFFKSKTAAVMERFKM 1955 G S D++ + TTL EL +Y IFL+ L +++FG +N + +Y M + F++ + + F + + ++W++++ + L+WD + N + + + +Y+E L+G+ R+RQ+R + C++ S CY KY++ N+D + K NP WT+T S + A ++G + +Y GGYI+ L+ ++T DL+ WI RGTRAVF+DF ++N N+NLFC +R++AEFP GG++TS+ KLLRY S ++YFI CE++F IF+ + I+ + + E K F++ W+ +M+++L+ + +SF Y + + ++ + D+YP F ++ + + + I+I +F A +KIFK+I FN+TM+ LSSTL R K+I GF++MF I+F A+AQL +L+FGS D+S Q S+ +QFRI+LGDF++ + +AN G IYF+ ++FFVFFVL+NMF+AII + Y +VK D +I + + + + V+E+ ++ Sbjct: 10 GGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLP--DDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGL-KRNPEWTHTPSSRT-APWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRL 528
BLAST of PKD2-3 vs. Ensembl Mouse
Match: Pkd2l2 (polycystic kidney disease 2-like 2 [Source:MGI Symbol;Acc:MGI:1858231]) HSP 1 Score: 280.411 bits (716), Expect = 4.022e-83 Identity = 186/523 (35.56%), Postives = 317/523 (60.61%), Query Frame = 3 Query: 408 GNKSNADIY------IMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQT-ISMSEFFKSKTAAVMERFKM 1955 G S D++ + TTL EL +Y IFL+ L +++FG +N + +Y M + F++ + + F + + ++W++++ + L+WD + N + + + +Y+E L+G+ R+RQ+R + C++ S CY KY++ N+D + K NP WT+T S + A ++G + +Y GGYI+ L+ ++T DL+ WI RGTRAVF+DF ++N N+NLFC +R++AEFP GG++TS+ KLLRY S ++YFI CE++F IF+ + I+ + + E K F++ W+ +M+++L+ + +SF Y + + ++ + D+YP F ++ + + + I+I +F A +KIFK+I FN+TM+ LSSTL R K+I GF++MF I+F A+AQL +L+FGS D+S Q S+ +QFRI+LGDF++ + +AN G IYF+ ++FFVFFVL+NMF+AII + Y +VK D +I + + + + V+E+ ++ Sbjct: 10 GGTSKHDLHYRREAEVNTTLEELLLYFIFLINLCILTFGMVNPHMYYLNKVMSSLFVDTSLP--DDERSSFRSIRSITEFWKFMEGPLIDGLYWDSWYGNKQLYSVKNSSRIYYENVLLGIPRVRQLRVRNNTCKVYPAFQSLVSDCYSKYTVENEDFSDFGL-KRNPEWTHTPSSRT-APWHWGFVGVYRDGGYIVTLSKSKSETKAKFVDLRLNNWISRGTRAVFIDFSLYNANVNLFCIIRLLAEFPATGGLLTSWQFYSVKLLRYVSYYDYFIASCEVIFCIFLFVFIIQELRKVNEFKSAYFRSVWNWLEMLLLLLCFLAVSFYAYCNMQSFLLLGQLLKNTDSYPDFYFLAYWHIYYNNVIAITIFFAWIKIFKFISFNETMSQLSSTLSRCMKDIVGFAIMFFIIFSAYAQLGFLVFGSQVDDFSTFQNSIFAQFRIVLGDFNFAGIQQANWILGPIYFITFIFFVFFVLLNMFLAIINDTYSEVKADYSIGRRPDFELGKIIQKSCFNVLEKLRL 528
BLAST of PKD2-3 vs. Ensembl Mouse
Match: Pkd1l2 (polycystic kidney disease 1 like 2 [Source:MGI Symbol;Acc:MGI:2664668]) HSP 1 Score: 144.05 bits (362), Expect = 2.405e-34 Identity = 116/457 (25.38%), Postives = 222/457 (48.58%), Query Frame = 3 Query: 504 GTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDD----------SAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAII 1844 G + N+++F +E +F ++GF P L R ++E+ + +K L+ P T+GN KLVG A +RQVR + C + L C+ YS+ +D SA N W Y S + +G ++LYGGGGY++ L +D ++I+ L + +W+D TRAVF++F V+N N+NLFC V + E G + T+ +L ++ + F++ E+ + +F+ YY + R+ KW F + W++ ++ ++L S + + R I ++ + D F + + D + I+ + ++ +K++ +R N M ++S L R+ +I GF + LI+ +A++ + L+FG Y + + + + LG F+Y+ + + + G++ + F+ FV++N+F+++I Sbjct: 1962 GQRDPNAYHFHRHLERSF-SQGFS---------PVLG-FRGFFEWANTTLVKNLY------GHHPGFVTDGN-----SKLVGSAHIRQVRVRESSCAVAQQLQDSLDGCHGPYSLGIEDLVDYGEGWNASAYNNSNGFPQAWRYQSQSQRRGYPMWGKLTLYGGGGYVVPLGTDHQSASRILQYLFDNSWLDALTRAVFVEFTVYNANVNLFCTVTLTLETSGLGTFFSHVTLQSLRLYPFTDGWHPFVVAAELTYFLFLFYYMVVQGKLMRKQKWGYFCSKWNLLEVAIILASWSALVVFVKRTILADRDLQRYREHRDEGISFSETAAADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMITSALRRAWGDISGFVAVILIMLLAYSFASNLVFGWKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPILGSLLIGSCIVFMTFVVLNLFISVI 2396
BLAST of PKD2-3 vs. UniProt/SwissProt
Match: sp|Q6IVV8|PKD2_DANRE (Polycystin-2 OS=Danio rerio OX=7955 GN=pkd2 PE=1 SV=1) HSP 1 Score: 417.927 bits (1073), Expect = 4.226e-131 Identity = 257/716 (35.89%), Postives = 418/716 (58.38%), Query Frame = 3 Query: 333 KQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSR--PETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQ-----------EELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 +++ C + + LW TR + N SN ++Y+ T LRE+ Y++FL+ L +I++G ++ N +Y+ M F++ G + F LS +W++ + L ++W+ W N++ PE + L+Y+E L+GV R+RQ+R + C + L + CY YS N+D AP P K+ W + +Y+G +S YGGGGY DL+ K+ + +LK W+DRGTRAVFLDF ++N N+NLFC VR++ EFP GG V S+ +LLRY S+++YF+ CE+ F +F++YY +E LE R + + FK+ W+ D+++V +S+ I NI R V+ ++ ++ + TYP F+ +++ F + +I +F++ +K+FK+I FNKTM LS+T+ R K++ GF++MF IVF+A+AQLAYL+FG+ D+S Q + +QFRIILGDFD+ + EA+ G IYF +VFF+F +L+NMF+AII + Y +VK D + +++ K M + K+K I DI D++ L FDE R ++ KG++D EIEA+F+KYD+DGDQ L +E +QM + LE E++ + +S + R S+SQ + E D + ++ EE L R+D +E+++ I+ KID V+ +E++E K+ + V+G+IL+ Sbjct: 120 QEHRSCGKRILEKMRVLWDTRLLGESN-SNREMYLKTVLREMITYILFLLTLCIITYGMVSTNMYYYTKVMSQLFLDTPLSSG--EPTNFKSLSTMEDFWKFTEGPFLNGMYWE-LWYNNKSLPENQS---LIYYENLLLGVPRLRQLRVRNESCSVHEDLRDEVYDCYNVYSPANEDKAPFGP-KNGTAWRFKDESSLGESSYWGQVSTYGGGGYYQDLSRTREKSANQLQELKNNLWLDRGTRAVFLDFSIYNGNVNLFCIVRLLVEFPATGGAVPSWQFQTVRLLRYVSSWDYFVGMCEVSFCLFVLYYLVEEALEIRLHRLRYFKSLWNCLDVLIVALSVPAIIMNICRTSAVSHRLHFLLENHSTYPNFEPLARLQVHFNNLAAIIVFLSWVKLFKFINFNKTMNQLSTTMSRCAKDLMGFAIMFFIVFLAYAQLAYLVFGTQVNDFSTFQACIFTQFRIILGDFDFSEIEEADSVLGPIYFTTFVFFIFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKSYNRAMVKLKLKKSSINDIPDSLQQA----AGKLSFDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELTEHEHQQMRDDLEKEREDLDLEHSSLPRPASGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKMKRRDVLGRILD 823
BLAST of PKD2-3 vs. UniProt/SwissProt
Match: sp|Q4GZT3|PKD2_BOVIN (Polycystin-2 OS=Bos taurus OX=9913 GN=PKD2 PE=2 SV=1) HSP 1 Score: 407.142 bits (1045), Expect = 2.946e-126 Identity = 247/701 (35.24%), Postives = 417/701 (59.49%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGN---LMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKI----SEAMNSEKDGSFKRQNSKSQINLRESDSN-------AIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR ++ + ++ + Y+ + LREL YL+FL++L ++++G ++++ +Y+ M F++ ++ F LS+ +W++ + L L+W ++P TE + +Y+E L+GV R+RQ+R + C +P L CY+ YS+ ++D AP P ++ W YTS + +++G I+ Y G GY +DL+ +T V++LK+ W+DRGTRA+F+DF V+N N+NLFC +R++ EFP GGV+ S+ P KL+RY + F++F+ CEI+F +FI+YY +E ILE R K F+++W+ D+V++++S++ I NIYR V + + + +T+P F+ ++ + F + ++ +F +K+FK+I FN+TM+ LS+T+ R K++FGF++MF I+F+A+AQLAYL+FG+ D+S Q + +QFRIILGD ++ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + +S+ + + + K+K + DI +++ G L FDE R +K KG+ D EIEA+F+KYD DGDQ L +E +QM + LE E++ + S SF R S+ + + V+ EE L R+D +E+++ I+ KID V+ +E +E KL ++V+G++L+ Sbjct: 202 LWGTRL-MEESSTDREKYLKSVLRELATYLLFLIVLCILTYGMMSSSVYYYTRIMSQLFLDT--PVSKMEKTNFKTLSSMEDFWKFTEGALLDGLYW-----KTQPSNRTEADNRSFIYYENLLLGVPRIRQLRVRNGSCSIPLDLRDEIKECYDVYSVSSEDRAPFGP-RNGTAWIYTSEKDLNGSSHWGMIATYSGAGYYLDLSRTREETAAQVANLKKNVWLDRGTRAIFIDFTVYNANINLFCVIRLLIEFPATGGVIPSWQFQPVKLIRYVTTFDFFLAACEIIFCLFILYYVVEEILEIRIHKLHYFRSFWNCLDVVIIVLSVVAIGINIYRTSNV-EALLQFLEDQNTFPNFENLAYWQTQFNNIAAVIVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALIKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEEDDDDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLD 888
BLAST of PKD2-3 vs. UniProt/SwissProt
Match: sp|A2A259|PK2L1_MOUSE (Polycystic kidney disease 2-like 1 protein OS=Mus musculus OX=10090 GN=Pkd2l1 PE=1 SV=1) HSP 1 Score: 389.808 bits (1000), Expect = 6.256e-122 Identity = 242/686 (35.28%), Postives = 400/686 (58.31%), Query Frame = 3 Query: 339 NSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIE 2396 +S C +C I LW T T + N ++Y+ TTLREL +Y++FLV + L+++G +++++Y+ M F++ D G + F +S+ +W++ L L+W W N++ + +Y+E L+G R+RQ+R + C + CY+ YS +D P P ++ WTY S +++G ++ Y GGGY +DL + + + L+E W+DRGTR VF+DF V+N N+NLFC +R+V EFP GG + S+ I KL+RY + +++FI+ CE++F +FI YY +E ILE + + + W+I D+VV+L+SI+ + F+I+R + VN+ + ++ DTY F+ ++ + + + ++NLF A +KIFKYI FNKTMT LSSTL R K+I GF++MF IVF A+AQL YL+FG+ ++S + +QFRIILGDFDY A+ AN G +YFV YVFFVFFVL+NMF+AII + Y +VK + + +S+F K + R +++ +++ D+Q + G + + F+++ T+++ G+ + EI A F+++D DGD +LD EQ+QM + LE E+ +N+E + + L + +V+ EE L R+ L+ ++ ++ +ID V S ++ +E Sbjct: 67 SSCCLHICRSIRG-LWGT-TLTENTAENRELYVKTTLRELVVYIVFLVDICLLTYGMTSSSAYYYTKVMSELFLHTPSDSG----VSFQTISSMSDFWDFAQGPLLDSLYWT-KWYNNQSLGRGSHSFIYYENLLLGAPRLRQLRVRNDSCVVHEDFREDILNCYDVYSPDKEDQLPFGP-QNGTAWTYHSQNELGGSSHWGRLTSYSGGGYYLDLPGSRQASAEALQGLQEGLWLDRGTRVVFIDFSVYNANINLFCILRLVVEFPATGGTIPSWQIRTVKLIRYVNNWDFFIVGCEVVFCVFIFYYVVEEILEIHLHRLRYLSSVWNILDLVVILLSIVAVGFHIFRTLEVNRLMGKLLQQPDTYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCAKDILGFAIMFFIVFFAYAQLGYLLFGTQVENFSTFVKCIFTQFRIILGDFDYNAIDNANRILGPVYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELAGQKDQLQLSDFLKQSYNKTLLRLRLRKERVSDVQKVLKGG----EPEIQFEDFTSTLRELGHEEHEITAAFTRFDQDGDHILDEEEQEQMRQGLEEERV----TLNAEIENLGRSVGHSPPGELGAEAARGQSWVSGEEFDMLTRRVLQLQCVLEGVVSQIDAVGSKLKMLE 736
BLAST of PKD2-3 vs. UniProt/SwissProt
Match: sp|Q13563|PKD2_HUMAN (Polycystin-2 OS=Homo sapiens OX=9606 GN=PKD2 PE=1 SV=3) HSP 1 Score: 392.119 bits (1006), Expect = 1.074e-120 Identity = 252/704 (35.80%), Postives = 414/704 (58.81%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGN---LMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKK-------KISEAMNSEKDGSFKRQNSKSQINLRESDSN-------AIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR ++ + +N + Y+ + LREL YL+FL++L ++++G +++N +Y+ M F++ + F LS+ +W++ + L L+W +P TE + +++E L+GV R+RQ+R + C +P L CY+ YS+ ++D AP P ++ W YTS + +++G I+ Y G GY +DL+ +T V+ LK+ W+DRGTRA F+DF V+N N+NLFC VR++ EFP GGV+ S+ P KL+RY + F++F+ CEI+F FI YY +E ILE R K F+++W+ D+V+V++S++ I NIYR V + + + +T+P F+ ++ + F + ++ +F +K+FK+I FN+TM+ LS+T+ R K++FGF++MF I+F+A+AQLAYL+FG+ D+S Q + +QFRIILGD ++ + EAN G IYF +VFF+FF+L+NMF+AII + Y +VK D + +S+ + + + K+K + DI +++ G L FDE R +K KG+ D EIEA+F+KYD DGDQ L +E +QM + LE E++ + M+S SF R S+ + E + V+ EE L R+D +E+++ I+ KID V+ +E +E KL ++V+G++L+ Sbjct: 200 LWGTRL-MEESSTNREKYLKSVLRELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLDT--PVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYW-----KMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP-RNGTAWIYTSEKDLNGSSHWGIIATYSGAGYYLDLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINLFCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTFDFFLAACEIIFCFFIFYYVVEEILEIRIHKLHYFRSFWNCLDVVIVVLSVVAIGINIYRTSNV-EVLLQFLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPIYFTTFVFFMFFILLNMFLAIINDTYSEVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSR---SFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLD 886
BLAST of PKD2-3 vs. UniProt/SwissProt
Match: sp|O35245|PKD2_MOUSE (Polycystin-2 OS=Mus musculus OX=10090 GN=Pkd2 PE=1 SV=2) HSP 1 Score: 389.808 bits (1000), Expect = 8.717e-120 Identity = 246/698 (35.24%), Postives = 410/698 (58.74%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEY-----------VTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR + N +N + Y+ + LREL YL FLV+L ++++G +++N +Y+ + FI+ + F LS+ +W++ + L L+W N + + +++E L+GV R+RQ+R + C +P L CY+ YS+ ++D AP P ++ W YTS + +++G I+ Y G GY +DL+ +T ++ L+ W+DRGTRA F+DF V+N N+NLFC VR++AEFP GGVV S+ P KL+RY +AF++F+ CEI+F FIIYY +E ILE R + F+++W+ D+V+V++S++ + NIYR+ + + + +++P F+ ++ + F + ++ +F+ +K+FK+I FN+TM+ LS+T+ R K++FGF++MF I+F+A+AQLAYL+FG+ D+S Q + +QFRIILGD ++ + EAN G +YF +VFF+FF+L+NMF+AII ++Y +VK D + +S+ + + + K+K + I +++ G L FDE R +K KG+ D EIEA+F+KYD DGDQ L E +QM + LE E++ + +S R +S + E D + V+ EE L R+D +E+++ I+ KID V+ +E +E KL ++V+G++L+ Sbjct: 198 LWGTRLMEESN-ANREKYLKSVLRELVTYLFFLVVLCILTYGMMSSNVYYYTRTLSQLFIDT--PVSKTEKTNFKTLSSMEDFWKFTEGSFLDGLYWKAQTSNH--TQADNRSFIFYENLLLGVPRLRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP-RNGTAWMYTSEKELNGSSHWGIIASYSGAGYYLDLSRTREETAAQLAGLRRNFWLDRGTRAAFIDFSVYNANINLFCVVRLLAEFPATGGVVPSWQFQPVKLIRYVTAFDFFLAACEIIFCFFIIYYVVEEILEIRIHRLSYFRSFWNCLDVVIVVLSVVAMVINIYRMSNA-EGLLQFLEDQNSFPNFEHVAYWQIQFNNISAVMVFLVWIKLFKFINFNRTMSQLSTTMSRCAKDLFGFTIMFSIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGDINFAEIEEANRVLGPLYFTTFVFFMFFILLNMFLAIINDSYSEVKSDLAQQKAEMELSDLIRKGCQKALVKLKLKRNTVDAISESLRQG----GGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEREHQQMRDDLEKEREDLDLEHSSLPRPMSSRSFPRSLDDSEEEDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLD 884
BLAST of PKD2-3 vs. TrEMBL
Match: A0A0H3YJQ9 (PKD2-3 OS=Schmidtea mediterranea OX=79327 GN=PKD2-3 PE=2 SV=1) HSP 1 Score: 1445.64 bits (3741), Expect = 0.000e+0 Identity = 754/754 (100.00%), Postives = 754/754 (100.00%), Query Frame = 3 Query: 207 MSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 2468 MSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST Sbjct: 1 MSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 754
BLAST of PKD2-3 vs. TrEMBL
Match: V3Z0D8 (Uncharacterized protein OS=Lottia gigantea OX=225164 GN=LOTGIDRAFT_229509 PE=4 SV=1) HSP 1 Score: 482.256 bits (1240), Expect = 7.742e-154 Identity = 287/741 (38.73%), Postives = 448/741 (60.46%), Query Frame = 3 Query: 306 SNDKINFDEKQNSKCSQMCEKITN---YLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSN---PGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSE-----KDGSFKRQNSKSQINLRES-----------------DSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILET 2444 ND + + C KI LW TR + K N ++Y+ TTLREL IY +FL++L +I+FG + +Y+ M + F+ D N K F ++N +W Y LK L+W+ +W N++ + +Y+E KL+GV R+RQ++ C + + C++ Y+ N+D+ P S+ W Y + + +++G ++ Y G GYI DL + +++++I+ +L W+ RGTRA+F+DF V+N N+N FC VR++ EFP GG + S+T KL+RY SAF++FI+ CE +FV+FI YY +E LE ++ + Q FK +W+I D++V+L++++C+ F+IYR + V +++ +++ + + Y F+++S ++ F + I+I +F+A +KIFKYI FNKTMT LSSTLGR K++ GF+VMF I+F+AF QL YL+FG+ D+S Q S + FRIILGDFD++ L AN G I+F+L+VFFVFFVLINMF+AII + Y +VK D M+++FK + V+++ +K KIVDIQ A+ D+NND + FDEWR +K +GYAD EIEA+F+KYD+DGD+VLD EQK+M L EK I++A +E + G+ R +S+ N SN + Y EE L+ R+D +E+++ I+ KID VL +E++E KL ++ +GKIL++ Sbjct: 44 GNDSRALQKSSKPQSRGCCYKILGGIRSLWATR-HTEETKENRELYVKTTLRELIIYFVFLIILCVITFGMTSTTMYYYTKVMSDLFL----DTPNSKAGTFRTVTNVDDFWRYTKEPLLKGLYWE-TWYNNQSVPEEQQGYIYYENKLLGVPRIRQLKVHSNSCVVHNDFKGVIQECFDSYAEGNEDTKTFGPEGSDTNGSAWNYQTETELEGSSHWGLLTTYSGAGYIQDLALNMSESSKIIDNLFNNLWVTRGTRAIFIDFTVYNANINFFCVVRLLIEFPATGGAIPSWTFRTVKLIRYVSAFDFFIMACEFIFVLFIFYYIVEEALEIKKHRLQYFKGFWNILDILVILLALVCMVFDIYRTLVVGEKLESLLSNKEQYADFERLSYWETRFSNTIAILVFMAWIKIFKYISFNKTMTQLSSTLGRCAKDLAGFAVMFFIIFLAFTQLGYLLFGTQVKDFSSFQNSFFTLFRIILGDFDFQQLEAANRILGPIFFMLFVFFVFFVLINMFLAIINDTYSEVKGDMANMKNEFEMADYFKKGYSRVLDKLNLKRDKIVDIQKALKTADINNDKQVDFDEWRQDLKTRGYADGEIEAMFAKYDIDGDRVLDEEEQKRMQADLANEKSAINKAYYNELGKTPRSGTAGRSSSRISFNDDSGDDSDDEDSGTKSSRTGRTSNGVSY---EEFTVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKLKRRETMGKILDS 775
BLAST of PKD2-3 vs. TrEMBL
Match: A0A3S1A8W4 (Uncharacterized protein OS=Elysia chlorotica OX=188477 GN=EGW08_006585 PE=4 SV=1) HSP 1 Score: 474.937 bits (1221), Expect = 1.468e-150 Identity = 277/714 (38.80%), Postives = 434/714 (60.78%), Query Frame = 3 Query: 360 CEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRP---NKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDG-SFKRQNSKSQI---------------NLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILET 2444 C + LW TR + + SN ++Y+ TTLREL IY++FLV+L +I+FG + +Y+ M + F++ D G F L++ +W Y + L+W+ W N + + + +Y+E KL+GV R+RQ+R C++ + CY+ Y+ +D+ P +N W Y S +++G ++ Y G G DL S + + + L ++ W+ RGTRAVF+DF V+N N+NLFC +R++ EFP GG + S+T KL+RY + +YF+L CEI+F IF++YY +E +LE +++K FK +W+I D++V+++S +C+ FNIYR I V+ +++ ++ Y F+++S ++ F + I+I +F+A +KIFKYI FNKTMT LSSTLGR K++ GF VMF+I+F+AF QL YL+FG+ D+S + + + FRIILGDFD+ L +AN G I+F+L+VFFVFFVLINMF+AII + Y +VK D ++++FK + ++++ K KIVDIQ A+ + D+N D + FDEWR +K +GYADCEIEAVF++YDVDGD+VLD EQK+M L+ +K A+N E D K ++S S++ + A V+ EE L+ R+D +E+++ I+ KID VL +E++E KL ++ +GKIL++ Sbjct: 73 CLRGVRSLWATR-QTEETTSNRELYVKTTLRELIIYIVFLVVLCIITFGMTSTTMYYYTKVMSDLFLDSTNDKGG----TFRTLTSVEDFWRYTKGPLVNGLYWE-KWYNDQNMSKPDMGYIYYENKLLGVPRIRQLRVHSNSCKVHEDFENFISECYDSYAESIEDTKPFGEYLNEPANTAWFYYSESDLGGSSHWGELNTYSGAGSYKDLNSTKAASLETIDHLFDKLWVTRGTRAVFIDFSVYNANINLFCVIRLLVEFPATGGAIPSWTFRTVKLIRYVTVMDYFVLACEIIFCIFLLYYTVEEVLEIKKLKLSYFKGFWNILDILVIIISFVCVGFNIYRTIEVDNKLTKLLEDPTVYADFERLSYWETRFSNAIAIAVFMAWIKIFKYISFNKTMTQLSSTLGRCAKDLAGFFVMFIIIFLAFTQLGYLLFGTQVKDFSSFENAFFTLFRIILGDFDFHQLEQANRILGPIFFMLFVFFVFFVLINMFLAIINDTYSEVKSDMANAKNEFEIADYFKKGYSKMLDKLNFKRDKIVDIQSALKSADINQDQRVDFDEWRQDLKSRGYADCEIEAVFARYDVDGDRVLDAEEQKKMFADLQEQKL----ALNKEYDDIGGKGRHSSSRLSSNGDSGDDSDDDENGTKSRSGRAANGVSYEEFTVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKLKRRETMGKILDS 776
BLAST of PKD2-3 vs. TrEMBL
Match: A0A267FRH5 (Uncharacterized protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig005060g3 PE=4 SV=1) HSP 1 Score: 474.937 bits (1221), Expect = 1.524e-150 Identity = 278/722 (38.50%), Postives = 441/722 (61.08%), Query Frame = 3 Query: 348 CSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRP-ETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDS---------------------NAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETF 2447 C + C+ +W TR D K + ++YI TTLREL IY IF+++L++I+FG ++ +Y+ + + F++ + N + + + N +W +++ + L+WD +W NS E N +Y+E KL+GV R+RQ+R C + SY + CY KYS D + S W Y S + ++ IS Y GGG+ ++L+ D T I+ +L + W++RGTRAVF+DF ++N N+NLFC +R+V EF GG + ++ + KLLRY +YFIL CE +F++FI+YY +E LE ++ KW+ F+ +W+ D++V+++S +C +FN+YR + V Q+++T++ ++ +P FD +S + + F H I+I +F A +KIFKYI FNKTMT LSSTLG K++ GF++MF IVF AFAQL YL+FG+ D+ Q SV + FRIILGDFD+ +L AN G I+F+LYVFFVFFVLINMF+AII + Y +VK D ++ M+++FK + + ++ + ++ KIVDIQ AI + DLNND L F+EWR +KQ+GYAD EIEA+F+K+D+DGD+VL+ EQ+QMH +LE +++ + + +NS++ + + + + D+ + V+ E L R+D +E ++ I+QKID VL +E +E KL ++ + ++L+ Sbjct: 107 CLKSCKHGLQSIWRTRDTQD-TKEDRELYIKTTLRELIIYCIFIIVLMIITFGMTSSTMYYYTKVLSDLFLDTKIE--NTTN-NYRSVGNMGDWWSFVNGPLMNGLYWD-TWYNSANFSDPREKNFIYYENKLLGVPRLRQLRVSNQSCNIASYFQGKISTCYAKYSYGVTDKSSFGLGNST-AWQYRSEEQLDGRSHNAEISSYDGGGFAVELSRDKATTQAILKELYSKLWVNRGTRAVFIDFTLYNANINLFCVIRLVTEFMATGGCLPTWDLRTVKLLRYVEPMDYFILACECVFMLFILYYIVEEALEIKKHKWRYFRCFWNCLDILVIVISTVCAAFNVYRTVAVGQKLTTLLQDENNFPDFDFLSYWQQQFNHGIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLMGFAIMFFIVFFAFAQLGYLIFGTQVKDFREFQQSVFTLFRIILGDFDFNSLQTANRVLGPIFFILYVFFVFFVLINMFLAIINDTYSQVKSDLSMQQNEFEMTDYFKQRASRMLSKLNLRRDKIVDIQKAIQSADLNNDKQLDFEEWRAELKQRGYADGEIEALFAKFDLDGDRVLNEEEQRQMHLELEGQRENLDQMINSKQAANEELEPDDEDEMEADGDALPAAATAASTRTSGGGGRGRGGGRKLVSPAEFQVLVKRVDRVEMSIGDIVQKIDSVLLKLELMERAKLRRREAMTRVLDAL 822
BLAST of PKD2-3 vs. TrEMBL
Match: A0A1I8GHK9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 474.937 bits (1221), Expect = 1.979e-150 Identity = 278/722 (38.50%), Postives = 441/722 (61.08%), Query Frame = 3 Query: 348 CSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRP-ETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDS---------------------NAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETF 2447 C + C+ +W TR D K + ++YI TTLREL IY IF+++L++I+FG ++ +Y+ + + F++ + N + + + N +W +++ + L+WD +W NS E N +Y+E KL+GV R+RQ+R C + SY + CY KYS D + S W Y S + ++ IS Y GGG+ ++L+ D T I+ +L + W++RGTRAVF+DF ++N N+NLFC +R+V EF GG + ++ + KLLRY +YFIL CE +F++FI+YY +E LE ++ KW+ F+ +W+ D++V+++S +C +FN+YR + V Q+++T++ ++ +P FD +S + + F H I+I +F A +KIFKYI FNKTMT LSSTLG K++ GF++MF IVF AFAQL YL+FG+ D+ Q SV + FRIILGDFD+ +L AN G I+F+LYVFFVFFVLINMF+AII + Y +VK D ++ M+++FK + + ++ + ++ KIVDIQ AI + DLNND L F+EWR +KQ+GYAD EIEA+F+K+D+DGD+VL+ EQ+QMH +LE +++ + + +NS++ + + + + D+ + V+ E L R+D +E ++ I+QKID VL +E +E KL ++ + ++L+ Sbjct: 121 CLKSCKHGLQSIWRTRDTQD-TKEDRELYIKTTLRELIIYCIFIIVLMIITFGMTSSTMYYYTKVLSDLFLDTKIE--NTTN-NYRSVGNMGDWWSFVNGPLMNGLYWD-TWYNSANFSDPREKNFIYYENKLLGVPRLRQLRVSNQSCNIASYFQGKISTCYAKYSYGVTDKSSFGLGNST-AWQYRSEEQLDGRSHNAEISSYDGGGFAVELSRDKATTQAILKELYSKLWVNRGTRAVFIDFTLYNANINLFCVIRLVTEFMATGGCLPTWDLRTVKLLRYVEPMDYFILACECVFMLFILYYIVEEALEIKKHKWRYFRCFWNCLDILVIVISTVCAAFNVYRTVAVGQKLTTLLQDENNFPDFDFLSYWQQQFNHGIAITVFFAWVKIFKYISFNKTMTQLSSTLGACAKDLMGFAIMFFIVFFAFAQLGYLIFGTQVKDFREFQQSVFTLFRIILGDFDFNSLQTANRVLGPIFFILYVFFVFFVLINMFLAIINDTYSQVKSDLSMQQNEFEMTDYFKQRASRMLSKLNLRRDKIVDIQKAIQSADLNNDKQLDFEEWRAELKQRGYADGEIEALFAKFDLDGDRVLNEEEQRQMHLELEGQRENLDQMINSKQAANEELEPDDEDEMEADGDALPAAATAASTRTSGGGGRGRGGGRKLVSPAEFQVLVKRVDRVEMSIGDIVQKIDSVLLKLELMERAKLRRREAMTRVLDAL 836
BLAST of PKD2-3 vs. Ensembl Cavefish
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:103043751]) HSP 1 Score: 418.313 bits (1074), Expect = 3.447e-132 Identity = 253/702 (36.04%), Postives = 416/702 (59.26%), Query Frame = 3 Query: 381 LWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSR--PETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAIN--NGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQ-----------EELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 LW TR ++ ++S+ ++Y+ LRE Y+ FL+ L +I++G ++ N +++ M F++ G+ F LS +W+Y + L ++WD W N++ PE + L+Y+E L+GV R+RQV+ C + L + CY YS ++D AP K+N W Y+ + +Y+G ++ Y GGGY DL ++ + + +LK+ W+DRGTRAVFLDF V+N N+NLFC VR++ EFP GG VTS+ +L+RY S+++YF+ CE++F +F++YY +E +LE R + + FK+ W+ D+++V +S I NIYR V+ ++ ++ + TYP F +++ F H ++ +F+A +K+FK+I FNKTM+ LS+T+ R K++ GF++MF IVF+A+AQLAYL+FG+ D+S Q + +QFRIILGDFD+ + E N G IYF +VFF+F +L+NMF+AII + Y +VK D + +++ K M + +++ + DI D++ G LN FDE R ++ KG++D EIEA+F+KYD+DGDQ L +E +QM + LE E++ + +S R S+SQ + E D + ++ EE L R+D +E+++ I+ KID V+ +E++E KL ++V+G++L+ Sbjct: 139 LWGTRL-MEDSESSREVYLKNVLRETVTYIFFLITLCIITYGMVSTNMYFYTKVMSQLFLDTPLSKGD--PTTFKTLSTMEDFWKYTEGPFLNGMYWD-VWYNNKSLPENQS---LIYYENLLLGVPRLRQVKVLNKSCPVHEDLKDEVYDCYSIYSPASEDKAPFG-LKNNTAWVYSEENILGESSYWGEVATYRGGGYYQDLARSREESARQLKELKDNLWLDRGTRAVFLDFSVYNGNVNLFCIVRMLVEFPATGGAVTSWQFQTVRLVRYVSSWDYFVGTCEVVFCLFVLYYMVEEVLEIRLHRLRYFKSLWNCLDVIIVTLSAPAIIMNIYRTSAVSNRLRYLLENHSTYPNFQPLAQVQVQFNHLAAVIVFLAWVKLFKFINFNKTMSQLSTTMSRCAKDLLGFAIMFFIVFLAYAQLAYLVFGNQLNDFSTFQACIFTQFRIILGDFDFSEIEETNRVLGPIYFTTFVFFMFMILLNMFLAIINDTYSEVKADMAQQRSEMEITDLIKKGYQKAMVKLRLRKTTVDDISDSLRQAGGKLN------FDELRQDLRGKGHSDAEIEAIFAKYDLDGDQELSEHEHQQMKDDLEKEREDLDLERSSLPRPMSGRSFSRSQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEAMERAKLKRREVLGRLLD 826
BLAST of PKD2-3 vs. Ensembl Cavefish
Match: pkd2l1 (polycystic kidney disease 2-like 1 protein [Source:NCBI gene;Acc:103031316]) HSP 1 Score: 389.037 bits (998), Expect = 6.210e-122 Identity = 254/711 (35.72%), Postives = 407/711 (57.24%), Query Frame = 3 Query: 324 FDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYS-IFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISE-----AMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKIL 2438 + EK++S C + LW T D + N ++++ TTLREL +Y++FLV + L+++G ++ ++Y+ M + F+N D G + F + +W Y L L+W SW N++ + + +Y+E L+GV R+RQ++ K C++ C++ Y+ DDS+ N + W Y + + + N++G ++ Y GGGY DL ++ ++++L W+D GTRAVF+DF +N N+NLFC +R+V EFP GG + S+ I KL+RY + ++YFI+ CEI+F +FI+YY +E ILE R K FK+ W+I D+V+++++I+ I FN++R I V++ + ++ Y F+ ++ + + + ++NLF A +KIFKYI FNKTMT LSSTL R +I GF++MF IVF A+AQL YL+FG+ +S + +QFRIILGDFDY + AN G IYF YVFFVFFVL+NMF+AII + Y +VK + + +++ K + + K+K +KI D+Q + +G L F ++R T+K+ G+AD EI A FSK+D DG+Q+LD EQ+ M ++LE ++ +S +N EK+G N K+ L VT ++ L ++ LE ++ + KID V+ + + K N + GK L Sbjct: 80 YHEKKSSGCCSFLLRGIKGLWGTTLTKDTTE-NRELFVRTTLRELVVYIVFLVDMCLLTYGMTSSTTYYYTKVMTDLFVNAPSDSG----VTFQSIGTMDDFWSYAQGPLLDGLYWT-SWYNNQSLQTGTHSFIYYENMLLGVPRVRQLKVKNKSCKVHKDFEEEISDCFDVYNEKKEDDSSFGLINGT--AWQYHTEKELKGSNHWGMLATYSGGGYYQDLALTKEESAGVLANLNNNLWLDHGTRAVFIDFSTYNANINLFCVIRLVVEFPATGGAIPSYQIRTVKLIRYITTWDYFIIGCEIVFCVFILYYIVEEILELRIHKLSYFKSIWNILDVVIIMLAIVAIVFNVFRTIKVDKLLGNLLKEPSIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSSTLARCATDILGFAIMFFIVFFAYAQLGYLLFGTEVESFSTFHKCIFTQFRIILGDFDYDGIERANRVLGPIYFFTYVFFVFFVLLNMFLAIINDTYSEVKEELASQKDDLQITDLIKQSYSKTFMKLKLKKEKISDVQKVLRSG----SKELEFKDFRETLKEMGHADHEISAAFSKFDYDGNQILDKEEQETMKQELEEKRDALSVELHNLGINYEKNGKETDDNEKTNSVL----------VTAQQFQMLVKQVVELECSLATTMAKIDVVMEKLGLQDAGKTNKKDATGKHL 768
BLAST of PKD2-3 vs. Ensembl Cavefish
Match: pkd1l2a (polycystin 1 like 2 [Source:NCBI gene;Acc:103044173]) HSP 1 Score: 149.443 bits (376), Expect = 3.642e-36 Identity = 117/458 (25.55%), Postives = 223/458 (48.69%), Query Frame = 3 Query: 504 GTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPN----------KSNP-GWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAII 1844 G + N+FY ++ +F N D + +++ ++ L LF +P T+GN KLVG AR+RQVR + C++ + + C+ YS +D P K+ P W Y + +A +G +++Y GGG+++DL + + + L E TW+D TRA+F++F V+N N+NLFC V ++ E G + +L + + F++ E+++ +FI YY + ++ KW+ F++ W++ DM ++++S + I R + NQ I D Y F++ + D + + I+ + +A +K++ +R N + ++STL R+ +I GF V+ I+F+A++ L++G Y + + + + LG F+Y+ + + N GA + F+ FV++N+F+++I Sbjct: 2109 GQRDPNAFYLTQHIQQSFSN-----------GISDSMTHGEVFQWANSTLLNNLF------GQQPGFITDGN-----SKLVGNARLRQVRVQDGSCRVDRSMRNSVPDCHAPYSWDMEDLGSYGPGWNPSIDANLSKTLPTPWQYQTQSRLRAHPIWGGVAVYRGGGFVVDLGPNRENASSSLQYLFENTWLDMFTRAIFVEFTVYNANVNLFCIVTLMFETTAVGAFQYRSELQSVRLYQSTGGLHIFVMASEVVYFLFIFYYMFQQGKLMKQQKWEYFRSKWNLLDMAIIILSWSALPVFIKRTLLGNQSIEYYQNHKDEYAGFNETATADAVLGYIIAFLVLLATVKLWHLLRLNPKLHMITSTLQRAWNDISGFIVVMTIMFLAYSVACNLLYGWKLYSYRTLLNAAQTIVSLQLGIFNYEEVLDYNPVLGAFIVGSCIIFMTFVVLNLFISVI 2544
BLAST of PKD2-3 vs. Ensembl Cavefish
Match: ENSAMXT00000006495.2 (pep primary_assembly:Astyanax_mexicanus-2.0:5:35007331:35041448:1 gene:ENSAMXG00000006274.2 transcript:ENSAMXT00000006495.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 140.198 bits (352), Expect = 2.129e-33 Identity = 106/407 (26.04%), Postives = 205/407 (50.37%), Query Frame = 3 Query: 681 WVNSRPETSTEGNLMYF----EIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSN-----------PGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENY 1856 W NS T+ G F KLVG AR+RQVR + C+ S + S C+ YS +D P ++ W Y + +A +G ++LY GGG+++DL D ++ ++ L E W+D TRA+F++F V+N N+NLFC V ++ E G + +L + + L E ++ +FI+YY ++ KW+ F+N W+I ++ ++L+S S I +++ +Q + + +P F + + D + + ++ + +A +K++ +R N + +++TL ++ +I F V+ +I+F+A++ ++ L+FG Y + + + + LG F+Y+ + + N GA + F+ FV++N+F+++I E + Sbjct: 1261 WANSSLLTNLFGQYSGFITDGNSKLVGTARLRQVRVQKSSCRKASSVRSSVPDCHAPYSWEVEDMGSYGPGWTSLIDSNMSKALFTPWQYQTQSRLRAHTVWGGMALYRGGGFVVDLEPDQQNSSSVLQYLFENAWLDIYTRALFIEFTVYNANVNLFCIVTLMLETTAVGAFQYRTELQNIRLFQTTDGIP--TLVSEAIYFLFILYYMFLQAKLMKQQKWEYFRNKWNILELAIILLSWSAFSVFIKKMVQGDQDLKYYQDHRNQFPSFYETAAADSVLGYLTAVLVLLATIKMWHLMRLNSKLNMITNTLQQAWSDISSFIVVIVIMFLAYSIVSNLLFGWKLYTYKTLIDAATAMVSLQLGIFNYEEILDLNPVLGAFIIGSCIIFMTFVVLNLFISVILEAF 1665
BLAST of PKD2-3 vs. Ensembl Cavefish
Match: pkd1a (polycystic kidney disease 1a [Source:ZFIN;Acc:ZDB-GENE-100707-1]) HSP 1 Score: 52.7582 bits (125), Expect = 2.329e-6 Identity = 48/243 (19.75%), Postives = 115/243 (47.33%), Query Frame = 3 Query: 981 DLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAI-EVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVL 1706 +L+ + ++ L W TRA+F++F ++N N +L ++ EFP +S + L + + +L +IFIIY+++ E + R+ + F W++ M +L++ + + ++ R + ++ + +++ F +++ +++ + LF+ +LK +RF + TL RS E+ ++ L++ +A++ + +L+F S Y+ + ++ L Sbjct: 3732 ELSRRMEDSRSLIQQLLSHQW----TRALFVEFSLYNTNTDLLAVFTLLLEFPVSERAQSSLDLKTCSLHTLHHGLDLSLFL-TLLLMIFIIYFSVREGVAAHRQGR-SYFLRVWNLAGMCTLLLAAVVSALHLSRSALATRLWASFLQQRESFTDFFPLAQQNQVLTQLNATLLFLLVLKASHQLRFLREWAVFGRTLRRSVWELLAAALALLVLLLAYSHMGHLLFHSVLEGYATVSSACL 3968
BLAST of PKD2-3 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 382.489 bits (981), Expect = 5.853e-122 Identity = 245/683 (35.87%), Postives = 391/683 (57.25%), Query Frame = 3 Query: 354 QMCEKITNYLWTTR-TKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNF--PCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEK--DGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSME 2387 Q C W TR T+++ + Y TTLREL IY++FL+ L L++FG +N N++Y+ M + F+ + F +S+ +W+ + L L+W+ W N + + + +E ++GV R+RQ++ + C + Y L RN CY+ YS +D + W Y S + +++G ++ Y G GY DL+ N++ ++ +LK+ W+D GTRAVF+DF +N N+NLFC VR+V EFP GG + S+ KL+RY SAF+YFI+ CE++F FI+YY +E LE R + FK+ W+ D++V+++S++ I FNI R I V+ + ++ + Y F+ ++ + F + ++IN+F A +KIFKY+ FNKT+T LSSTL R K++ GF+VMF I+F A+AQ YL+FGS D+S + +QFRIILGDFD+ A+ AN G IYF Y+FFVFFVL+NMF+AII + Y VK + + +FFK ++ + KMK I D+Q A+++ +L +D WR + + G++D EI A FSK+D D D VLD EQKQ+ +LE +K K++E + + K D S K ++ VT+++ R+ +E+++ ++ K++ +L+ +E Sbjct: 2 QHCRVCCPGFWGTRLTEVNSTREQ---YFKTTLRELIIYVVFLIDLCLLTFGMMNTNTYYYTKVMMDLFVES--PVSPIDGTNFNSISSMDDFWKVVQGPVLDGLYWE-KWYNG-DQLPVNLSFIQYENVMLGVPRVRQLKVRNGSCTI--YPLFRNIIPGCYDGYSCGEEDKETF-GRGTGTAWKYWSEEELSGSSHWGLLAQYSGAGYYRDLSRRKNESAPMLQELKDYLWLDHGTRAVFIDFTTYNGNINLFCVVRLVVEFPLTGGALPSYQFRTVKLIRYVSAFDYFIMACEVIFCCFILYYVVEECLELRLHGMKYFKSVWNCLDIIVIVLSMVAIIFNICRTIAVSNLLGALLNDPNIYADFEYLAFWQTQFNNMLAINVFFAWIKIFKYVSFNKTLTQLSSTLARCAKDVLGFAVMFFIIFFAYAQTGYLVFGSQVEDFSSFVNCIFTQFRIILGDFDFHAIENANRILGPIYFTTYIFFVFFVLLNMFLAIINDTYTDVKAELADTKDDFEIGDFFKQGYKNMLNKLKMKKDDIADMQRALDSA----GKHLEYDIWRKNLIRLGHSDEEIAAAFSKFDKDSDNVLDEDEQKQLRAELEGQKDKLNEDIEALKTMDNSGKPGDASR--------------VTKDDFNRFASRVAKMESSMDSLMSKVESLLTKLE 656
BLAST of PKD2-3 vs. Ensembl Sea Lamprey
Match: pkd2l1 (polycystic kidney disease 2-like 1 [Source:ZFIN;Acc:ZDB-GENE-030616-558]) HSP 1 Score: 348.591 bits (893), Expect = 7.301e-108 Identity = 241/718 (33.57%), Postives = 394/718 (54.87%), Query Frame = 3 Query: 327 DEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFI------NEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXI--NMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKR----------------QNSKSQINLRESDSNAIEYVTQEELLF-----LNIRMDGLENNVQLILQKIDQVLSSMESI 2393 +E Q+ + + + LW TR D ++ D Y+ TTLRELF+Y+ FL+ L++++FG + + + AM+N F+ N+ +F ++ F D +W+ + L L+W+ W N P + + +Y+E L+GV R+RQ++ + C + + CY YS +D A P P W Y++S +++G ++ Y GGGY +DLT +++ ++ DL ++ W+DRGTRA+ +DF +N N+NLF +R++ EFP GG V S I KL+RY + +YFIL CE +F FI+YY +E ILE K+ FK+ W+ D++V+++S++ I FN+YR + VN+ + ++ + Y F ++ + + + +++N+F +K FKY+ FNKTMT LSSTL R K++ GF+VMF I+F A+AQL YL+FG+ D+S + +QFRIILGDFD+ A+ AN G +YF YVF VFFVL+ NMF+AII + Y +VK++ + +FK + ++ IVD+ ++ + + +D+WRL +K+ G++D EIEA F+K+D D + VLD E K M ++L+++K KDGS R S IN + N Y L+ L +D LE ++ + K+D +++ + S+ Sbjct: 79 EEDQSGGPKKSRKSVLRGLWGTRLTED--ITDRDKYVKTTLRELFVYIAFLINLIILTFGMTSDLMYKYTLAMDNLFLQNTVSPNDSVNFNSI--FTFDD------FWKVVQGPVLNGLYWE-KWYNDIPLVENQ-SFIYYENFLLGVPRIRQLKVRNDSCTVHADFQKDVQGCYAAYSEDAEDKASFGPATGTP-WKYSTSSDMNGSSHWGLLATYSGGGYYLDLTRSKSESAILLQDLFDKQWLDRGTRAILIDFSSYNGNINLFSVIRLLVEFPPTGGAVPSSQIYTVKLIRYVTGSDYFILACEGIFCCFILYYIVEEILELSIHKFAYFKSVWNCLDLLVIMLSVVAIIFNVYRTVTVNKLLKALLDEPNRYGNFQFLAFWQTQYNNMVAVNVFFCWIKFFKYVSFNKTMTQLSSTLARCAKDVLGFAVMFFIIFFAYAQLGYLLFGTQVEDFSTFSNCIFTQFRIILGDFDFNAIENANRVLGPLYFTTYVFVVFFVLLPKNMFLAIINDTYAEVKNELAEKENEFDVGGYFKKVYLDIRKKLGKNRGNIVDMISVLD----ASSQKINYDDWRLKLKRLGHSDEEIEAAFAKFDKDKNSVLDSNEMKLMRDELKSQK----------KDGSMDRVLSPCVLLNYVIFRNLDCSAKCINNLSGEINHRRYADDISTLYNVYKRLVQNVDNLEQSISTMFSKVDVIMNKVGSL 769
BLAST of PKD2-3 vs. Ensembl Sea Lamprey
Match: pkd2 (polycystic kidney disease 2 [Source:NCBI gene;Acc:432387]) HSP 1 Score: 226.098 bits (575), Expect = 2.498e-63 Identity = 162/562 (28.83%), Postives = 287/562 (51.07%), Query Frame = 3 Query: 828 CYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTN-QIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIF-KNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISIN---LFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAI-NNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQIN-----------------LRESDSN--AIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKIL 2438 CY YS N++ P P S W + S + G++ YG GGY + L +DS Q ++ L++ +W+DR TR + +D + N N+ L+ VR+ EFP GG++T+ ++TP + L + C +L + IYY +E +LE R + F + W+ D+ ++ + ++ +F ++ I + + S F +S Q+FI + +F+A +K+ ++ +T+T L R ++ G++++F VF+AFAQLA+L+FG D+S + +L+Q RI+LGDFD+ +L A+ G IYFV YVF V +++ MF+AI+ E Y + K ++ + +S K V++R K ++ IQ + +G +N F WR +K +G+AD EIEAVF++Y DGD L EQ QM L EK+ I ++ K+ S+ + +R + + V++EE L R++ +E+++ ++ K+D V+ +E++E Q+L + V+ +++ Sbjct: 146 CYGPYSSANENKDPFGPANSTV-WRFDSEA---GVPWQGALGWYGPGGYAVRLPADSRTAAWQELAALRDASWLDRATRLLSVDAALLNPNLRLYMVVRLSMEFPPTGGILTALSLTPGRPL--GTPLWDARAVCGLLAALLTIYYLVEEVLELRNLGPAGFLSSPWTFLDISIIALCVVGTAFGVHHGILSSSLLGEA--SSSRAMSFSTVSTVAEWEQNFIIVTGVIVFVAWIKVVRFGSMCRTLTMCGCALTRCAWDLLGYTLVFATVFLAFAQLAFLIFGGALPDFSSFSSCILTQVRILLGDFDFSSLEAASRIMGPIYFVSYVFCVGLIMMVMFLAIVSEAYSEEKSEQAHSQPQFQLSSVIKQ--VKVVDRLSCKKPRVAGIQKTLPPSGQIN------FATWRQNLKGQGFADAEIEAVFARY--DGDGALTRAEQLQMRRDLRLEKQTIRLHISVSPREKKKKHQVTSRDDDDDDDDGDSDEDDDITVVRRGNHHQGGGGGVSREEFRVLVRRVNQMEHSIGSVVSKMDAVMVKLEAMERQRLRRRDVLSRLI 689
BLAST of PKD2-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007306.1 (pep scaffold:Pmarinus_7.0:GL480012:400827:419749:1 gene:ENSPMAG00000006595.1 transcript:ENSPMAT00000007306.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 98.9821 bits (245), Expect = 1.956e-21 Identity = 62/284 (21.83%), Postives = 129/284 (45.42%), Query Frame = 3 Query: 1008 NQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFT-ITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENY 1856 +IV++L +W+D TRAV +F +N+N +LFC V ++ EF G I ++ + E I+F I ++ A L E+ FK++W+I +++ + + + ++ + + + F ++ +D+ ++ +F++ +K+ +++ + L + I GF+V+ ++VF +F QL L+F + +Y T + F ++LG Y L AN G + + + FV++N + I+ E + Sbjct: 784 TEIVANLSSASWLDHSTRAVLTEFTGYNMNTDLFCSVTLLLEFSQGAGDAHGHAYIHVFRIESFVGKLETLTGVVYIVFAILLVIIAATEALRLSELGVAYFKSFWNIAELLSITLGAASVVTYFIKMSVATRTLEKFRTDPHKFVNFQELVTWDQQLSELLATLVFVSTIKVLGHMKSLRQFEVLVGAFSEARDHIQGFAVIVVVVFCSFGQLTSLLFAGSLRNYRTFTTCLEQLFSLLLGQPGYGELYAANRVLGPLIYFAFTSVNTFVIVNFSLGILSEGF 1067
BLAST of PKD2-3 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002645.1 (pep scaffold:Pmarinus_7.0:GL476683:134:12081:-1 gene:ENSPMAG00000002415.1 transcript:ENSPMAT00000002645.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 74.7146 bits (182), Expect = 1.316e-14 Identity = 70/299 (23.41%), Postives = 140/299 (46.82%), Query Frame = 3 Query: 1017 VSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLR----YSSAFEYFIL--CCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQH---------FISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVK 1868 +S L++ +W+D T ++ F+++N N NLFC V ++ E +++ PS L+ +++ Y IL I ++I +Y+ VI + K++ K ++ + IM I+ I ++I +Q+S + ++ F + Y L+ H F+ + LF+A L+I R+N TM+ + ++ FS++F ++ I+++ + + + G+ Y SV S F + G + L A G A+ + ++ +L+NM V +I E Y + + Sbjct: 26 MSYLEQNSWVDARTTGLYAQFIIYNANANLFCLVEVLVE------SLSADMFQPSSNLKVFRLFNNRISYIILDNVAYIFYLIISMYFLTCVIFSITKEKFEYLKKPMNVAE-------IMNITLMIMKLI---KQVSRS-PALGSHLNFFFLINYCTLYSHKPLILLSTQFLGLVLFLATLRILPLFRYNTTMSEAVTLAAHCAHKLCSFSLIFFVLLISYSLIFWNVLGTRVGAYRSFGKSVGSLFAALHGAPVFGDLYAAGGYMAALLYFSFMLLFTVLLLNMMVVVIEEVYTRFR 307
BLAST of PKD2-3 vs. Ensembl Nematostella
Match: EDO47023 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RN85]) HSP 1 Score: 415.231 bits (1066), Expect = 2.206e-131 Identity = 264/728 (36.26%), Postives = 425/728 (58.38%), Query Frame = 3 Query: 348 CSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNL--MYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLR---------------------------ESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILET 2444 C ++I LW TR D + S+ +++I TTLREL IYL+F+ +L +++FG ++ +YF M + F+ N F D++ ++W Y L+W+ + N++ T + +L +YFE K++G R RQ+R C + S CY YS +D + WTY + + Q +Y+G ++ Y GGG+ L +T QI+ DLK+ W+DRGTRAVF+DF V+N N+NLFC VR+V E+P GG + SF KL+RY F++F++ CE +F++FIIYY IE LE ++ K + FK++W++ D+VV+++ + + FN+YR + V +S+++ Y FD + + F + +++ +F A +K+FKYI FNKTMT LSSTL + K++ GF++MF I+F A+AQL YL+FG+ D+S + S+ + FRIILGDFD+ + AN G ++F+ YVFFVFFVL+NMF+AII + Y +VK D ++++FK ++ + K +KI+DIQ A+ + D+N D+ L F+EWR +K +G+AD EIEAVF+KYD+DGD++LD EQ++M E LE +K ++++ + + R S S+++ R V+ EE L+ R+D +E+++ I+ KID VL +E++E KL ++ + K+L++ Sbjct: 84 CWTRFKRIIRGLWRTRQTEDTD-SDREMHIKTTLRELIIYLVFITILCILTFGMTSSTMYYFTKVMRDLFVESSMSNRN----TFKDITTMNEFWMYTTETLSDGLYWE-QYYNNQNVTKPKDDLGFIYFENKILGRPRFRQLRVLNDSCTVHDDFKSVIKECYAAYSPNVEDMNTF-GKMNGSAWTYQTEKDLQGRSYWGRMTTYSGGGFTQLLAPTKAETQQIIEDLKQNLWLDRGTRAVFIDFTVYNANINLFCIVRLVFEYPPTGGCIPSFNFRTVKLIRYVDTFDHFVMACEGIFILFIIYYTIEEGLEIKKHKMKYFKSFWNVLDVVVIMLGYVAVVFNLYRTMAVGDLLSSLLEDGSQYANFDSLGFWQTQFNNMVAVAVFFAWIKVFKYISFNKTMTQLSSTLSKCAKDVAGFAIMFFIIFFAYAQLGYLIFGTQVRDFSTFEDSIFTLFRIILGDFDFHQIENANRVLGPLFFMTYVFFVFFVLLNMFLAIINDTYAEVKSDIASQESEFEITDYFKKGYQNMLNKLSFKREKILDIQKALKSADVNQDNKLDFEEWRANLKSRGHADAEIEAVFAKYDLDGDRILDEDEQRRMQEDLEGQKAELNDEIEEMERQKESRPKSASRMSFRGSDADSDDDDDDSQGGLSGRVGSAAGHRRGGGGGGGVSYEEFNVLSRRVDRMEHSIGSIVSKIDAVLVKLEAMEKAKLKRRETMAKLLDS 804
BLAST of PKD2-3 vs. Ensembl Nematostella
Match: EDO44744 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR6]) HSP 1 Score: 165.236 bits (417), Expect = 9.068e-42 Identity = 134/446 (30.04%), Postives = 216/446 (48.43%), Query Frame = 3 Query: 609 LSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPM-----RPNKSN-----PGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEF-REIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEF 1913 +S+ +W + + V + L+ +SW N R + G L ++G ARMRQ+R K C++ C YS +D+ P+ RP SN W Y S ++ Y G ++LY GGGY DL K +++ LK W+DR TRA+F++F V++ NL C ++ E GG + +++ RY+ F F+L CEILFV+F +Y+ + E RE F YWS ++V+ S I R + T + F ++ D++F + + F LK + RFNK M+ L++TL S KE+ FS++F +VF+AF YL+F + + + ++V + ++LG F Y+ L + N F Y V F+LINMF++II EN+ +VK + + + +F Sbjct: 667 VSDITSFWNWTEAVLIPGLY-SESWYNGR--SDKPGFLADHTSWMLGTARMRQLRVKAGDCKVHDVYSGYLAQCNGPYSWDTEDTTPVFRPGWRPAPSNYSTAQNAWKYRDSSELRSLPYLGKLALYSGGGYAFDL-GKKEKAMAMLAQLKRDKWVDRSTRAIFVEFTVYSPYTNLHCVGYLLLEVLPSGGTSPFSELLVTRIDRYAGNFMIFVLLCEILFVLFTVYFTYKQGKEIAREGVAYHFHEYWSWVELVLSGCSWTSIVLYFVRFGINKSTVLTYHKDTSVFVNFHALAASDQVFGYVYAFVAFFVSLKFLRLFRFNKRMSLLATTLKCSAKELAHFSIVFGLVFMAFVHFCYLIFSTELYIFHTVLSTVETLISVMLGKFSYERLLQTNRLLAPFMFFFYSIVVVFILINMFISIIIENFQRVKSQNDLQSNEYEIVDF 1108
BLAST of PKD2-3 vs. Ensembl Nematostella
Match: EDO48595 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RIZ7]) HSP 1 Score: 153.295 bits (386), Expect = 6.376e-40 Identity = 124/449 (27.62%), Postives = 225/449 (50.11%), Query Frame = 3 Query: 609 LSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSY---LLSRNFPCYEKYSIFNDDSAPMRPNKSNPGW------------------------TYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTI-TPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIIL-GDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVK 1868 + + +W++ + + ++ D +W N++P EG L LVG+ R+RQ+R + C + +R PCY YS A + + PGW Y ++ + G LYGGGGY+ DL ++ +++ +LK+ WID TRAVF++ +VF + + F V + E GG T +I T S S + CE++ ++ +IY+ I +++ + FK+ W+ +++ VL +I I +I+R + +Q ++ V + F + + + +++ +F+ +K+ + ++FNK ++ L+ ++ +S K + +SV+FL+ FIAFAQ+A+L FG T YS + +QF + + GD D++AL ++G G IYF Y+ + +LINMF+AI+ E Y +V Sbjct: 1 IGSEENFWKWAETYMVPGMY-DPTWYNNQPFEYKEGFLSNRIGYLVGMPRLRQLRVENDECPIGDRYDSFATRLRPCYPHYSF----KAEYKTLYNRPGWDALTQNETFFHSEFELYQMCPRPWRYKTASSLHTLPFQGDKDLYGGGGYVADLGYTASSALRVMHNLKKNNWIDERTRAVFMEVLVFEPSNSYFSAVTYLYERLATGGGTTYRSIKTMSLYGSRSHGLQSLYAVCELVLILIVIYFIIAELIKLYRQRCAYFKSAWNWIEIIQVLAAIATIVLSIFRRYHASQLVNRVHENPFKTSSFHYVVMWSEIENALMAVLIFVITVKLLRILKFNKHISLLAGSMKKSAKRLVSYSVVFLVAFIAFAQVAFLAFGPTTTAYSTVVRVFRTQFSMFVGGDPDWEALKSSSGFIGPIYFFGYMTAMATILINMFIAILNEAYKEVH 444
BLAST of PKD2-3 vs. Ensembl Nematostella
Match: EDO40051 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S8E5]) HSP 1 Score: 153.295 bits (386), Expect = 1.570e-39 Identity = 116/454 (25.55%), Postives = 215/454 (47.36%), Query Frame = 3 Query: 543 MENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFE----IKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNP--GWTYTSSQVSQA----DNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHD 1874 +EN F+ ++ G+ K F ++ +TR YW +L + + +F + W N + + +L Y ++ VAR+RQ+R + C + L C + YS ++ + P P W Y + + + + + + +K + L E W+D+ TRAVF +F ++N N NLFC V ++ E GG+ +I +L RY +F+ CEI++++F Y+ I + ++ KN WSI ++ V +S+ + R+ + + + + + + D + + + +F + +KI + +RFN+ M+ L+ TL +I F +++ I F A+AQLA L+FG NA + + S + +LG F K +S+ N G +F +Y + F+LINMF++II +++ +V D Sbjct: 41 VENVFLQASYN-GSTK---FDEIGSTRDYWPWLKDTVIPSIF-IEKWYNDQ-----DYHLGYLADTPTAWVLAVARLRQLRMQKHTCPLLPALQHVIPSCNDFYSSDEEERGMLLPGWKEPKTAWQYQTGEELKTFPYWGQKATYSAGGYVQVFPPSTAKNYDKAQALADALNENDWLDKYTRAVFTEFSIYNANSNLFCVVTLLIEQLPTGGIFKFPSILTLRLYRYVGGEMFFVAACEIIYLLFTAYFIFREIKQAYKLGLDKLKNPWSILEIFVTCLSLSMVVLYFLRIKFTAEVVKDMRNDPTRFVSLHYTAFLDEWIKCLMGLIVFFSFIKIVRLLRFNRRMSLLAQTLKLCIPKIGAFVIVYGIAFFAYAQLACLVFGQNAEGFMTIPRSAATLMDTLLGKFTLKEMSDINRLIGPTFFYIYTLSMIFILINMFMSIINDSFAEVNSD 484
BLAST of PKD2-3 vs. Ensembl Nematostella
Match: EDO48489 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ00]) HSP 1 Score: 144.821 bits (364), Expect = 5.610e-37 Identity = 119/424 (28.07%), Postives = 216/424 (50.94%), Query Frame = 3 Query: 627 YWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKV---IPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSA---FEYFILCCEILFVIFIIYYAIEVILEFREIKWQ---IFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIIL-GDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVK 1868 +WE+ D+ L L+ + W N +P EG + E +VG+ R+RQVR K P MP + RN SI +P W Y S+ + ++ G +Y GGGY+ DL + + +++S+L++ WID T VF++F VF +LF V+ + E GG T T+ L+ Y+SA + F C+++ ++ I+++ + +EF +I Q K +W+ +++ +L ++ I ++ Y ++ + V + D I + + +S+ +FI +K + IRFN+++ ++ T+ +S K I F ++F+ V +AF QL +L FGS +T YS S+ S +++L GD + L + N G + +Y+ + +L+NMF+AI+ ++Y + K Sbjct: 51 FWEWTDSTLLPALY-EPQWYNGKPFEYDEGFISSREAFVVGMPRLRQVRLKPEDKTPWNMPMWKPVRNLT--RSMSILKLQDICPKP------WRYQSASALHSLSFTGLDLVYDGGGYVADLGYNMWQAKEVISNLQKNNWIDDKTGGVFVEFTVFEPTTSLFSAVKYLYERFRTGGTNTRATV--RTLVLYASADTNMQSFFQVCQLMLMLMILFF---LFVEFGKIYRQGREYPKQFWNWMELIQILCTVAAIVMFFFKEKYTSEFVQRVRDNPFETSSTDYIVLWSDCEIYLLSLVIFIITIKFLRLIRFNRSICQMTGTITKSAKSIANFFIVFVAVLLAFTQLGFLAFGSRSTPYSSFFQSLRSCLQMVLGGDMHFFELQDINRILGPAFAFVYMLSMTMILLNMFLAILNDSYEETK 460
BLAST of PKD2-3 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724]) HSP 1 Score: 386.726 bits (992), Expect = 3.280e-121 Identity = 234/621 (37.68%), Postives = 368/621 (59.26%), Query Frame = 3 Query: 336 QNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMN 2198 Q K C LW T + +N + YI TTLREL +YL+FL+ + L+++G +++++YF AM + F+N G D G + F + +W + L L+W W N + + + +Y+E L+GV RMRQ++ K C++ F CY+ Y +D + WTY + + + +++G +S Y G GY DL ++ +I+S L + W+ RGTR VF+DF +N N+N+FC + ++ EFP GG V S+ I KLLRY + ++YFIL CE +F +FI+YY +E +LE R ++ K+ W+I D+VV+L++++ I+FN++R I V+ + ++ + + Y F+ ++ + + + ++NLF A +KIFKYI FNKTMT LS+TLGR K+I GF+VMF IVF A+AQL YL+FG+ +S + +QFRIILGDF++ A+ +AN G IYFV YVFFVFFVL+NMF+AII + Y +VK + T + +++ K R K+K KI D+Q A+ G + F +++ T+ + G+ D EI A FSK+D DG+QVLD EQ++M +L+ ++ +S +N Sbjct: 74 QRVKKKSGCCSFIKGLWGT-ALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSGGDAG----VAFQSIGTMADFWSFAQGPLLDGLYWT-KWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGL-INGTAWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELN 683
BLAST of PKD2-3 vs. Ensembl Medaka
Match: pkd2l1 (polycystin 2 like 1, transient receptor potential cation channel [Source:NCBI gene;Acc:100820724]) HSP 1 Score: 384.8 bits (987), Expect = 3.322e-119 Identity = 234/621 (37.68%), Postives = 367/621 (59.10%), Query Frame = 3 Query: 336 QNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMN 2198 Q K C LW T + +N + YI TTLREL +YL+FL+ + L+++G +++++YF AM + F+N G D G + F + +W + L L+W W N + + + +Y+E L+GV RMRQ++ K C++ F CY+ Y +D WTY + + + +++G +S Y G GY DL ++ +I+S L + W+ RGTR VF+DF +N N+N+FC + ++ EFP GG V S+ I KLLRY + ++YFIL CE +F +FI+YY +E +LE R ++ K+ W+I D+VV+L++++ I+FN++R I V+ + ++ + + Y F+ ++ + + + ++NLF A +KIFKYI FNKTMT LS+TLGR K+I GF+VMF IVF A+AQL YL+FG+ +S + +QFRIILGDF++ A+ +AN G IYFV YVFFVFFVL+NMF+AII + Y +VK + T + +++ K R K+K KI D+Q A+ G + F +++ T+ + G+ D EI A FSK+D DG+QVLD EQ++M +L+ ++ +S +N Sbjct: 74 QRVKKKSGCCSFIKGLWGT-ALTENVSNNREKYIRTTLRELLVYLLFLLDICLLTYGMTSSSTYYFTKAMTDLFVNSGGDAG----VAFQSIGTMADFWSFAQGPLLDGLYWT-KWYNQQSLNNGNQSFIYYENMLLGVPRMRQIKMKNNSCKVHQDFKDEIFGCYDVYDEKKEDDLNFGLINGT-AWTYHTEKEMRGSSHWGLLSTYSGAGYYQDLDRTRERSAEILSTLMDNCWLGRGTRVVFIDFSAYNANINMFCVISLMVEFPATGGAVPSYQIRTVKLLRYVTRWDYFILGCEAVFCVFILYYMVEEVLELRIHRFSYLKSVWNILDIVVILLALVAIAFNVFRTIKVDNLLGKLLENPNIYADFEFLAFWQTQYNNMNAVNLFFAWIKIFKYISFNKTMTQLSTTLGRCAKDILGFAVMFFIVFFAYAQLGYLLFGTEVDTFSTFVKCIFTQFRIILGDFNFDAIDQANRVLGPIYFVTYVFFVFFVLLNMFLAIINDTYSEVKEELTSQKDELQITDIIKQSYMKTFTRLKLKKDKITDVQKALQAG----SGEIQFKDFKQTLIEMGHTDGEISAAFSKFDRDGNQVLDAEEQERMKRELQEKRDALSTELN 683
BLAST of PKD2-3 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 380.948 bits (977), Expect = 3.910e-118 Identity = 247/720 (34.31%), Postives = 409/720 (56.81%), Query Frame = 3 Query: 327 DEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGN--LMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAIN--NGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQ-----------EELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 D ++ C + + LW T DG+ SN + Y+ LREL Y+ FL+ + ++++G I+ N +Y+ AM F++ N K F LS +W+Y L ++W+ W N++ S GN +Y+E L+GV R+RQVR C + L CY Y+ N+D++P P ++ W +T+ A ++G +S YGGGGY DL+ ++ + LK+ W+DRGTRA+FLDF V+N N+NL C R++ EFP GGV+TS+ +L++Y S+++YF+ CE+ F +F++YY +E +LE + FKN W+ D+++V +S++ I +I R + + + + ++ FD ++ F + ++ +F +K+FK+I FNKTM+ LS+T+ R K++ GF++MF I+F+A+AQLAYL+FG+ D+S Q SV +QFRIILGDFD+ + EAN G IYF+ +V F+FF+L+NMF+AII + Y +VK D + + M++F K + + ++K + DI D++ G LN +DE +K+KG+ + EI+A+F+KYD DGD L ++ +QM + LE E++ + NS S R ++Q + E D + ++ EE L R+D +E+++ I+ KID V+ +E +E KL + V+ ++L+ Sbjct: 124 DRHEHPGCMKRIFQNIRILWGTELMEDGD-SNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPK--TFRSLSTMEDFWKYTQGPFLGGMYWE-VWYNNQ---SLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGP-QNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAA-MGGDLLKGLENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQAGGKLN------YDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLD 828
BLAST of PKD2-3 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 380.178 bits (975), Expect = 2.434e-117 Identity = 247/720 (34.31%), Postives = 409/720 (56.81%), Query Frame = 3 Query: 327 DEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGN--LMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAIN--NGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQ-----------EELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 D ++ C + + LW T DG+ SN + Y+ LREL Y+ FL+ + ++++G I+ N +Y+ AM F++ N K F LS +W+Y L ++W+ W N++ S GN +Y+E L+GV R+RQVR C + L CY Y+ N+D++P P ++ W +T+ A ++G +S YGGGGY DL+ ++ + LK+ W+DRGTRA+FLDF V+N N+NL C R++ EFP GGV+TS+ +L++Y S+++YF+ CE+ F +F++YY +E +LE + FKN W+ D+++V +S++ I +I R + + + + ++ FD ++ F + ++ +F +K+FK+I FNKTM+ LS+T+ R K++ GF++MF I+F+A+AQLAYL+FG+ D+S Q SV +QFRIILGDFD+ + EAN G IYF+ +V F+FF+L+NMF+AII + Y +VK D + + M++F K + + ++K + DI D++ G LN +DE +K+KG+ + EI+A+F+KYD DGD L ++ +QM + LE E++ + NS S R ++Q + E D + ++ EE L R+D +E+++ I+ KID V+ +E +E KL + V+ ++L+ Sbjct: 124 DRHEHPGCMKRIFQNIRILWGTELMEDGD-SNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPK--TFRSLSTMEDFWKYTQGPFLGGMYWE-VWYNNQ---SLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGP-QNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAA-MGGDLLKGLENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSVFTQFRIILGDFDFFEIKEANPVLGPIYFITFVLFIFFILMNMFLAIINDTYSEVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQAGGKLN------YDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLD 828
BLAST of PKD2-3 vs. Ensembl Medaka
Match: pkd2 (polycystin 2, transient receptor potential cation channel [Source:NCBI gene;Acc:100192346]) HSP 1 Score: 326.25 bits (835), Expect = 8.512e-98 Identity = 224/722 (31.02%), Postives = 384/722 (53.19%), Query Frame = 3 Query: 327 DEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGN--LMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALS--EANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAIN--NGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQ-----------EELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILE 2441 D ++ C + + LW T DG+ SN + Y+ LREL Y+ FL+ + ++++G I+ N +Y+ AM F++ N K F LS +W+Y L ++W+ W N++ S GN +Y+E L+GV R+RQVR C + L CY Y+ N+D++P P ++ W +T+ A ++G +S YGGGGY DL+ ++ + LK+ W+DRGTRA+FLDF V+N N+NL C R++ EFP GGV+TS+ +L++Y S+++YF+ CE+ F +F++YY +E +LE + FKN W+ D+++V +S++ I +I R + + + + ++ FD ++ F + ++ +F +K+FK+I FNKTM+ LS+T+ R K++ GF++MF I+F+A+AQLAYL+FG+ D+S Q SV S+ ++ ++ + L ++G G IC + VK D + + M++F K + + ++K + DI D++ G LN +DE +K+KG+ + EI+A+F+KYD DGD L ++ +QM + LE E++ + NS S R ++Q + E D + ++ EE L R+D +E+++ I+ KID V+ +E +E KL + V+ ++L+ Sbjct: 124 DRHEHPGCMKRIFQNIRILWGTELMEDGD-SNRERYLWNVLRELLTYIAFLITICILTYGMISTNMYYYTKAMSQLFLDAPLSSENPK--TFRSLSTMEDFWKYTQGPFLGGMYWE-VWYNNQ---SLPGNQSFIYYENILLGVPRLRQVRVHNETCSIHEDLRDEVQGCYGVYTPSNEDNSPFGP-QNGTAWVHTTESKMNASTHWGQVSKYGGGGYYQDLSRTREESGLQLQFLKDHLWLDRGTRAIFLDFSVYNGNVNLVCIARLLVEFPATGGVLTSWQFQTVRLIKYVSSWDYFVGVCEVAFCLFVLYYVVEEVLEIHIHRLHYFKNLWNCLDVLIVTLSVVAIIMSITRAA-MGGDLLKGLENYTSHTSFDSLANLQVQFNNMAAVIVFFCWVKLFKFINFNKTMSQLSTTMSRCAKDLVGFAIMFFIIFLAYAQLAYLVFGTQVNDFSTFQGSV-SRTDLL---YNLRPLHFLYSHGEKG----------------------ICTVSLFVKADMAQHRSEMEMTDFIKKGCTKALVKLRLKKTTVDDISDSLRQAGGKLN------YDELLQDLKEKGHTEAEIQAIFAKYDQDGDLELTEHDHQQMRDDLEKEREDLDLERNSLTRPSSGRSFPRTQDDSEEDDDEDSGHSSRRRGSSSGGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEGMERAKLKRRDVLVRLLD 804
BLAST of PKD2-3 vs. Planmine SMEST
Match: SMESG000059487.1 (SMESG000059487.1) HSP 1 Score: 1560.04 bits (4038), Expect = 0.000e+0 Identity = 811/811 (100.00%), Postives = 811/811 (100.00%), Query Frame = 3 Query: 36 FERSVCVCDPIKKLYFVNSNTTRNFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 2468 FERSVCVCDPIKKLYFVNSNTTRNFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST Sbjct: 14 FERSVCVCDPIKKLYFVNSNTTRNFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 824
BLAST of PKD2-3 vs. Planmine SMEST
Match: SMESG000059487.1 (SMESG000059487.1) HSP 1 Score: 1517.29 bits (3927), Expect = 0.000e+0 Identity = 788/791 (99.62%), Postives = 791/791 (100.00%), Query Frame = 3 Query: 96 TTRNFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 2468 +++NFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST Sbjct: 4 SSKNFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 794
BLAST of PKD2-3 vs. Planmine SMEST
Match: SMESG000059487.1 (SMESG000059487.1) HSP 1 Score: 1516.13 bits (3924), Expect = 0.000e+0 Identity = 793/812 (97.66%), Postives = 795/812 (97.91%), Query Frame = 3 Query: 66 IKKLYFVNSNTTR-----------NFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 2468 I +FVN + R NFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST Sbjct: 9 ISHKHFVNDSVVRENSGKADSLGINFILTESKKTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 820
BLAST of PKD2-3 vs. Planmine SMEST
Match: SMESG000059487.1 (SMESG000059487.1) HSP 1 Score: 1496.87 bits (3874), Expect = 0.000e+0 Identity = 779/780 (99.87%), Postives = 780/780 (100.00%), Query Frame = 3 Query: 129 KTKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 2468 +TKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST Sbjct: 17 ETKFSLIRIFHRLTSIYLQQFSEFSRMSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLRELFIYLIFLVLLLLISFGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNYYGSISLYGGGGYIIDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIYFVLYVFFVFFVLINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETFPLYGIST 796
BLAST of PKD2-3 vs. Planmine SMEST
Match: SMESG000018492.1 (SMESG000018492.1) HSP 1 Score: 435.647 bits (1119), Expect = 1.928e-140 Identity = 291/742 (39.22%), Postives = 439/742 (59.16%), Query Frame = 3 Query: 222 TRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQMCEKITNYLWTTRTKIDGNKSNADIYIMTTLREXXXXXXXXXXXXXXXXGTINANSFYFAAAMENAFINEGFDFGNLKDLQFPDLSNTRQYWEYLDNVALKFLFWDDSWVNSRPETSTEGNLMYFEIKLVGVARMRQVRSKVIPCQMPSYLLSRNFPCYEKYSIFNDDSAPMRPNKSNPGWTYTSSQVSQADNXXXXXXXXXXXXXXXDLTSDSNKTNQIVSDLKEQTWIDRGTRAVFLDFVVFNINMNLFCKVRIVAEFPNFGGVVTSFTITPSKLLRYSSAFEYFILCCEILFVIFIIYYAIEVILEFREIKWQIFKNYWSIQDMVVVLVSIMCISFNIYRVIYVNQQISTVIVSDDTYPQFDQISKYDRLFQHFISINLFIAILKIFKYIRFNKTMTHLSSTLGRSGKEIFGFSVMFLIVFIAFAQLAYLMFGSNATDYSGMQTSVLSQFRIILGDFDYKALSEANGPFGAIXXXXXXXXXXXXXINMFVAIICENYVKVKHDETINNQTISMSEFFKSKTAAVMERFKMKTKKIVDIQDAINNGDLNNDSYLGFDEWRLTMKQKGYADCEIEAVFSKYDVDGDQVLDPYEQKQMHEQLEAEKKKISEAMNSEKDGSFKRQNSKSQINLRESDSNAIEYVTQEELLFLNIRMDGLENNVQLILQKIDQVLSSMESIELQKLNNQKVIGKILETF 2447 TR + AM S ++YEY T + ++ NF + C + LW TR D K + +YI TTLREL IY+ FL +L++ISFG +++F + F F N F + +W++L L L+W +W N+ TS + N +Y+E +L+G+ R+RQVR + C +PS C+ YS+ ++ S P W YT+S V Y G ++ YGGGG+ ++L S + + L WIDRGTRAV +DF V+N N+NLFC +++V EFP GG++ S KL+RY + ++F+L CE+LFV+FI+YY +E LE + +K++ F + W+I D++V++ S+ C FNI R + V I T++ +D+ +P F+ ++ + F + I+I LF+A +K+FKYI FNKTMT LS+TL R K++ GF++MF I+FIAFAQL YL+FG+ D+S +Q + + FRIILGDFD+ L A+ FG +YFV YVFFVFFVL NMF+AII + Y +VK + ++++ K +T V+ + +K KI+DIQ+A+ GD NND + FDEWR+ +K +GY D EIEAVF++YD DGD+ LD EQ M ++LE +K + + Q KS+I L ++ + V+ EE LN R+D ++NN ++I+ KID VL ++ESIE K +++ +G IL T Sbjct: 9 TRELPSAM-----SDDSYEYGKSTKDSI--EETNFINP--NSCWNRFKNGIRSLWATRHTED-TKVDRQLYIKTTLRELVIYIFFLAVLVIISFGMTTVQAYWFTNLLSGLFTTSNF---NDNSGTFAASTTESDFWKFLTGPLLNGLYWT-TWYNNINFTSDQINFLYYENRLIGLPRLRQVRVRNDSCSIPSDFQGEIKQCFAAYSMSSESKDSYGQQNSTP-WVYTNSSVLDTTEYQGIVATYGGGGFYVNLNSTQVDSFNTIMTLFNNLWIDRGTRAVIIDFTVYNANINLFCYIKLVGEFPPTGGLLVSSQFRTVKLIRYVGSIDFFVLACELLFVVFIVYYIVEESLEIKMLKFEYFFSIWNILDILVIIFSLTCSIFNIVRTLTVQNIIQTLVANDNIHPNFESLTFWQLQFDNLIAITLFLAWVKVFKYISFNKTMTQLSATLSRCSKDLAGFAIMFFIIFIAFAQLGYLIFGAQVNDFSKLQYCIYTLFRIILGDFDFAQLEVAHRIFGPLYFVFYVFFVFFVLFNMFLAIITDTYGEVKEELANQKNEFEIADYVKERTEVVLAKLHLKKDKIIDIQNAVLAGDTNNDGKMDFDEWRVELKSRGYGDAEIEAVFARYDTDGDKALDEAEQIAMQKELEDQKNSL----------DLEIQYEKSEI-LNKTRDVILPVVSLEEYRALNRRVDRMDNNTRVIVTKIDTVLEALESIEKDKARSRETMGIILNTL 724 The following BLAST results are available for this feature:
BLAST of PKD2-3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of PKD2-3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of PKD2-3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of PKD2-3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of PKD2-3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of PKD2-3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of PKD2-3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035484 ID=SMED30035484|Name=PKD2-3|organism=Schmidtea mediterranea sexual|type=transcript|length=2601bpback to top protein sequence of SMED30035484-orf-1 >SMED30035484-orf-1 ID=SMED30035484-orf-1|Name=SMED30035484-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=755bp MSVTDTRNVLEAMECETLSSNAYEYNNKTVKTFSNDKINFDEKQNSKCSQback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|