Cytochrome P450 2K1-like protein

Query:  152 LC-TFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQF-WFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSD 1570
            LC +F+L  +++ +  RR  +P G    PT   LP +G + QI+   I + +    K +G VF V +GM  +++ + Y+ VK A +D+G  +SGR     S       GI   +G+ W+  R F L  L +FGMGK    + V++E   L+EEL   +    D + ++     N+I      KRF   D K +N   L+    +   +L   W   + + +  PLL D      +++ K+      Y +E+V EH+ SLD+N+   D ID FLIK  Q K +  S   F    L+    +L +AG ETT+TTL +  L + K+  +  KV EEI ++IG+ R P   DR  + YT AV+ EI R S + P  + H    D+    Y +PK   + + L +   D+K +  P  F P  FL  D NG+ K   ++    F  GKR CAGE LA+ME F+F T+I+Q F ++  +D+ +
Sbjct:    9 LCLSFMLLFSLWRQSCRRRKLPPG----PTP--LPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRF---DYKDQNFLTLMKRFNENFRILNSPW---IQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNP-RDFIDCFLIKMEQEKDNQKS--EFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFL--DKNGNFK--KSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKN 466          

Query:  305 RLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1549
            +L K++GS++ V  G R V++L+ YQ VK A VD G  +SGR    +       +GIAF  G  W+  R F +++L +FGMGK    E + +E   LL EL   +G+  D + ++     NII       RF   D++L  I  LI           F   + P   ++D  P L DW+     RI ++F  +       V +H+ SLD  S   D I  FL K  + K     +  F    LL  +  LL  G +T +TTL  +FL + KY  +Q +V EEI  ++G+ R P   DR  + YT AV+ E+ R + + P+ L HR   D++  G+ +PK   V + L   H+D   +  P+EF PE FL  D N   K +       F  G+R C GESLA+ME F++ T+I+Q F ++
Sbjct:   57 KLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLIND--------NFQIMSSPWGELYDIFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASLDPRSP-RDFIQCFLTKMAEEKED--PLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFL--DANQSFKKSP--AFMPFSAGRRLCLGESLARMELFLYLTAILQSFSLQ 460          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSD 1570
            P    LP +G L Q+E   I + + RL ++ G VF +  G + +++++ Y+ VK A +D    +SGR  L  +  A  + GI F +G  W+  R F L  L ++GMGK  +   +++E   LLE L   QG+  D + LI     N+I+     K F   D+K   +  L            F   + P   +++  P    ++   +HR  IK+   V +Y  E V EH +SLD N    DL D  L++  + K S   +  +T   +     +L  AG ETT+TTL +  L + KY  I++K+HEEI  +IG  R P   DR+++ Y  AV+ EI R  ++ P  L H A  D+   GY +PK  +V   L +  +D + +  P++F PE FL+   NG  KY+  +    F  GKR CAGE LA+ME F+   +I+Q F ++   D  D
Sbjct:   34 PGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDL-PAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNE--------NFHLLSTPWLQLYNNFPSFLHYLPG-SHRKVIKNVAEVKEYVSERVKEHHQSLDPNCP-RDLTDCLLVEMEKEKHSAERL--YTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNE--NGKFKYS--DYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKD 468          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSD 1570
            P    LP +G L Q+E   I + + RL ++ G VF +  G + +++++ Y+ VK A +D    +SGR  L  +  A  + GI F +G  W+  R F L  L ++GMGK  +   +++E   LLE L   QG+  D + LI     N+I+     K F   D+K   +  L            F   + P   +++  P    ++   +HR  IK+   V +Y  E V EH +SLD N    DL D  L++  + K S   +  +T   +     +L  AG ETT+TTL +  L + KY  I++K+HEEI  +IG  R P   DR+++ Y  AV+ EI R  ++ P  L H A  D+   GY +PK  +V   L +  +D + +  P++F PE FL+   NG  KY+  +    F  GKR CAGE LA+ME F+   +I+Q F ++   D  D
Sbjct:   34 PGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDL-PAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNE--------NFHLLSTPWLQLYNNFPSFLHYLPG-SHRKVIKNVAEVKEYVSERVKEHHQSLDPNCP-RDLTDCLLVEMEKEKHSAERL--YTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNE--NGKFKYS--DYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKD 468          

Query:  287 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDK-LRNIN------DLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            + + + R  +K+G VF V  G R V++L   + ++ A VD    +SGR ++          G+ F +G  W+  R F +  + DFGMGK    E +++E   L+EEL   +G  +D + L    T NII      KRF   D + L+ +N       LI+ V  Q  L + +   L  F              HR   K+   ++ Y    V++HR++LD  S  +DLID +L+  H  K  + +   F+   L   +L L  AG ETT+TTL + FL M KY  + ++V+ EI  +IG  R P  +DR  + YT+AV+ EI R S + P+ + H     +S  GY +PKD  VF  L     D   +EKP  F P+ FL  D NG +K T  E    F +GKR C GE +A+ E F+FFT+I+Q F +
Sbjct:   51 LLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQ--LFELFSGFLKYFPG-----------AHRQVYKNLQEINAYIGHSVEKHRETLD-PSAPKDLIDTYLL--HMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFL--DANGALKKT--EAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSM 459          

Query:  182 FWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR-WRLMSSLLAANN-SGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKR-VDASDLIHLYTVNIISKFTMNKRFSRGD-DKLRNINDLI-THVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKH-FDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFE 1543
            +WK ++    PKG   +P    LPF+G +HQ     + +Y++ L K +G  F +       I+L DY+ +K AFV+ G  ++ R  R   +LL  ++ +GI   DG +W+ QR   LK+L DFG+G+++  E V +    +L +LE +  K+ VD    I L   N+I++      +   D +K +    ++  H+   +  +     A P    +P++ D      H IK+   + H + +EEV    K  D  SE E+ +  ++ +  Q    TG+  G     L    L+  +AG+ETT+ +L W   FM KY  +Q KV +EI++ +G  R P+ +D+ ++ YTQAV+ E+ R S++ P    H+   ++ I+G  VP  +LVF+ L++   ++ V+E P+ F P R+L +D     K    + +  F +GKR C GE LA+ME F+ F++++Q++E
Sbjct:   20 YWKVSKY---PKG--PLP----LPFIGNIHQFPPDNVQKYFDVLSKTYGPCFTIWIPF-PAIVLTDYEHIKDAFVNQGDTFTYRAHRSPETLLPVHDHTGILASDGDHWRLQRRTSLKILRDFGLGRNLMEEQVIRSVHEMLIQLENINDKKNVDVFWPIQLCVGNVINETLFGFHYKYEDSEKFKTFVKIVDKHLRHLQGKMPLLVSAFPWLKHVPIVGD---IGYHNIKNNISSYHTFIEEEVATQVKKYDGESEPENFVHAYMQQMKQ----TGN-PGLDITNLCATVLDFWLAGMETTSNSLRWHLAFMMKYPEVQDKVRKEILDNVGTARLPSMSDKPNMPYTQAVIHEVQRCSNMIPFLGSHQCKEETEIHGNRVPAGSLVFAQLWSVMRNDTVFEDPETFNPSRYLQSDGKTFDKAVLEKTI-PFSIGKRNCVGEGLARMELFLIFSALIQKYE 461          

Query:  152 LCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPI--FRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL-MSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRF-SRGDDKLRNINDLITHVAKQKDLLQ-FWFFALPIFDKMPLLCDWIISRTHRIKHF-DAVHKYFQEEVDEHRKSLD---LNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            L TFL    ++  + +R   P G         LP  G L  I  P   ++ +ER  KK+G V+    G    I++N +  +K  F+ D   Y+ +  L M +L      GI   +G  W+  R F L  + DFG+GK++  E +  E  ++   L+   G   D  ++      N++++     RF    +++ + +  +I   A+    L  F    +PIF K  LL + +      IK F D    +F ++++ HR  +D   LNSE  D ++ FL K+ + + S G  E +++ QLL + ++L  AGL TTT T+ W+  ++  +  +Q K+HEE+  +IG +R  TT D+ DL Y  A ++E  R  ++ PL L H    D+ I+G+ +PK   V + +     +E+V+  P  F P+RF+  D NG +K    + L  F +GKR C GE LA+ME F+F  + + R+++  +++   ++ + +     G V   ++   I T+R
Sbjct:    6 LLTFLTIYFVYELYWKRRNFPPG------PCPLPVFGNLLSIANPPPGYKAFERWTKKYGDVYTFWIGNTPHIMINTWDKIKETFIRDADTYTNKVVLPMVTLSRGGEYGIIDSNGAMWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDVPEVFDHAVANVVNQLLFGYRFMGPKENEYQELKHIIDSPAEIFGKLHIFLAMNIPIFAK--LLPESLYEGP--IKTFRDTTLAFFNKQIEAHRHRIDFEDLNSESTDFVETFL-KEQKRRESEGDSETYSNIQLLNVCIDLWFAGLNTTTNTITWAISYVLHHPEVQDKIHEELDKVIGSDRLITTADKNDLPYFNASINESQRGINILPLNLQHATTRDTVIDGFKIPKGTGVVAQISTVMNNEEVFPDPYTFNPDRFI--DENGKLKKV--DELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKIHPSKEGLPSMAKGS-----GPVVAPRLFTAILTRR 494          

Query:  233 PTEKGLPFVGVLHQIETPIFRY--YERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMS-SLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDD----KLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHF-DAVHKYFQEEVDEHRKSLDLN---SEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            P    LP  G L  I  P   Y  +ER  KK+G ++    G    I++N +  +K  ++ D   Y+ + RL +  L      GI   +G  W+  R F L  + DFG+GK++  E +  E  ++   L+   G   D  ++      N++++     RF    +    +L+ I +  T +  +  +  F    +P+  K  L+ +++       K F D    +F ++++ HR+ +DLN   SE  D ++ FL K+ + + S G  E F++ QL  + ++L  AGL TTT T+ W+  ++  +  +Q KVHEE+  +IG +R  TT D+ DL Y  A ++E  R  ++ PL L H    D+ ING+ +PK   V + +     +E+V+  P  F P+RF+  D +G +K    E L  F +GKR C GE LA+ME F+F  + + R+++
Sbjct:   27 PGPCPLPVFGNLLSIANPPPGYEAFERWTKKYGDIYTFWIGNTPHIMINTWDKIKETYIRDAETYTNKVRLPALDLFRGGEYGIIDSNGATWREHRRFALSTMRDFGLGKNLMQENILMEVQDVFARLDAKLGSETDIPEVFDHAVANVVNQLLFGYRFVGPKESEYQELKRIIEAPTDLFGKPHM--FLAMNIPVIAK--LMPEFMYEGP--FKDFRDTAFAFFNKQIEAHRQEVDLNDLNSESTDFVETFL-KEQKRRESEGDSETFSNVQLSNVCMDLWFAGLNTTTNTITWAISYILHHPEVQDKVHEEMDKVIGSDRLITTADKNDLPYFNAFINEAQRGINIVPLNLQHATTRDTVINGFKIPKGTGVVAQISTVMNNEEVFPDPHTFNPDRFI--DEHGKLKRV--EELAPFSVGKRSCPGEGLARMELFLFIANFLNRYKI 464          

Query:  179 IFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPI--FRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL-MSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRG-DDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQE----EVDEHRKSLDLN-SEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            ++WK   R   P G    PT   LP +G L  +  P   ++ + R   K+G ++    G R  I+++ Y+ +K  F+ DG  Y+ +  +         + G+   +G  W+  R F +    DFG+GK    + +  E  ++    +   G+ VD +D+      N+I++     RF     D+ R I       + +     F  F++ +   +P +  +I+     +  F    K F E    +++ H+K +D    E  D ++ FL +Q + +AS G  E F+  QL  M L+L  A L TT+ T+ W F +   Y   QQK+HEE+  +IG ER   T D+ +L YT A ++EI R +++ PL L+H    D+ + GY +PK   V + +    +DE V+ +P  F PERFL  D  G +K    E L  F +GKR+C GE LA+ME F+F  +   R+ V
Sbjct:   18 LYWK---RRNWPAG----PTP--LPLIGNLLSLRNPAPGYKAFARWTAKYGDIYTFWLGTRPYILVSSYEALKETFIKDGETYADKKPMAFQESFRGGSYGVVETNGPFWREHRRFAIHQFRDFGLGKDRMEQRIMLEVEDIFNNCDKTIGEGVDLTDIFDRAVGNVINQMLFGYRFDETRADEFRTIRAFFNFNSGE-----FASFSMRVQFFLPWM-GYIMPGPTILDRFKKYQKGFTEFFGTQIENHKKEIDFELEENSDYVEAFLKEQRKREAS-GDFESFSTKQLSNMCLDLWFAALMTTSNTMTWCFAYTLNYLDAQQKLHEELDRVIGSERHINTADKPNLPYTNAYINEIQRTANLVPLNLLHMTTRDTVLKGYNIPKGTGVVAQISTVMYDENVFPEPYIFKPERFLDDD--GKLKKV--EQLVPFSVGKRQCLGEGLARMELFLFIANFFNRYRV 462          

Query:  152 LCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVG--VLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRW-RLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGD-DKLRNINDLITHVAKQKDLLQFWFFA-LPIFDK-MP------LLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSE-GEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIG 1597
            +C FL    ++WK   R  +P G    PT   LPF+G  +   +E P +  + R  K+ G V+    G    +I+  Y  +K  FV DG  Y  ++ +  +  L     GI   +G  W T R F L  L DFG+GK +  E +  E  ++  + +   GK  D   +++    N+I++     RF   + ++   +  L+ +  KQ   ++ +  A +P   K +P      LL DW           ++ + +F  +++ HRK +D +SE  +D  + +L K+ + + + G  E F++ Q     L+L +AG+ TT TT+ W+  ++  +  + QK++EE   ++G +R  T  D+ +L Y  AV++E  R +++ P+ L H    D+ INGY V K   V + +     DEK++ +P +F P+RF+  D NG  K    E L  F +GKR+C GE LA+ME F+F  +   R+++  +  V   L ++  +G
Sbjct:   10 VCLFLF-HELYWK---RRSLPPG----PTP--LPFMGNTLAMLLEKPGYECFRRWTKQFGGVYTFWMGNIPYVIIGSYDLLKETFVRDGDTYKDKYPQPFNEKLRGGMYGIVESNGHMWSTHRRFALSTLRDFGLGKDLMQEKILIEVEDIFRKYDAQLGKEQDIQVVLNNAIANVINQTIFGYRFDETNQEEFERMRHLVEYQEKQFATVKVYVEAFVPTIGKFLPGKSLDQLLDDWR----------NSFYTFFDTQIENHRKKIDFDSEESQDYAEAYL-KEQKKQEALGEFELFSNTQFSNTCLDLWLAGVSTTNTTVNWTICYVLNHPDVLQKMNEEFDQVVGSDRLVTMGDKNNLPYFNAVLNESQRCANIVPINLFHATTKDTVINGYPVKKGTGVIAQISTVMLDEKIFPEPYKFNPDRFI--DENG--KPIKIEQLIPFSIGKRQCPGEGLARMEIFLFLANFFNRYKISPSSKVFPNLDKKDNVG 479          

Query:  221 LRRIPTEK-GLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR--WRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGM-----GKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLL-CDWIISRT-HRIKHFDA-VHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFT----DFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAE 1558
            LR++P    GLP +G L  + +     +  L K++GS+F+ R G +  ++++DY+ ++  F  +   ++GR     M +L   N  GI    G+ W+ QR F+   L  FGM     GK    + +  E    +  L    G+ VD S +I +   N+I    M+ RFS  D K R  N LI    +        F  +   D +P + C   IS   ++I    A + +++Q+ +D+H++S D N+   DL+D +L +  + KA     E F     + QL+++ ++L  AG+ET  TTL W  +FM +     ++V +E+  ++G+ R PT  D + L  T++ + E  R SS+ PLA  H    D  +NGY +P  + V   + + H D  +WEKP+EF P RF+ T+  G ++    E    FG+G+R C G+ LA+ME F+FF S M  F++   E
Sbjct:   50 LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL---NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMR-------LFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNI-RDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE--GKVR--KPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493          

Query:  221 LRRIPTEK-GLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR--WRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGM-----GKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLL-CDWIISRT-HRIKHFDA-VHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFT----DFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAE 1558
            LR++P    GLP +G L  + +     +  L K++GS+F+ R G +  ++++DY+ ++  F  +   ++GR     M +L   N  GI    G+ W+ QR F+   L  FGM     GK    + +  E    +  L    G+ VD S +I +   N+I    M+ RFS  D K R  N LI    +        F  +   D +P + C   IS   ++I    A + +++Q+ +D+H++S D N+   DL+D +L +  + KA     E F     + QL+++ ++L  AG+ET  TTL W  +FM +     ++V +E+  ++G+ R PT  D + L  T++ + E  R SS+ PLA  H    D  +NGY +P  + V   + + H D  +WEKP+EF P RF+ T+  G ++    E    FG+G+R C G+ LA+ME F+FF S M  F++   E
Sbjct:   50 LRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRRE--EFTGRPDTPFMQTL---NGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMR-------LFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNI-RDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTE--GKVR--KPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPE 493          

Query:  149 YLCTFLLGAAIFWKFTR-RTP--IPKGLRRIPT-------EKGLPFVGVLHQIETPIFRYYERLIKKHGS-VFAVRYGMRDVIILNDYQTVKSA-----FVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDD-KLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRT--HRIKHFDA-VHKYFQEEVDEHRKSL--DLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEI---VNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            +LC  L+G  I+   +  R P   P G R +P         K    VG  H +       +ER  K   S +  ++ G   V++   ++ VK       F     N+  R R M +       GI   DGQ W   R F +K + + G G+S     +  E   LL +LE  + + ++    +    +N++      KR +R +D  LR + DL+   +K  D+         +  + P L      RT  + I+  +  ++ +F + ++EHR+ L  D +    DLI  +L ++ + +++ G    F + QL+   L+  IAG +TT+ T+  + + ++    +Q+K+  ++   V     + FP  + R+  +Y  A + E+ R   + P+    RA+  + + GY +PK+A +  +L + H D++ W+ P EF PERF    I+   K   +E    FGMG+RRC G++LA+   F F   I+Q F V     V  A    +++   G+    K  K  F KR
Sbjct:    6 FLCAILIGFVIYSLISSARRPKNFPPGPRFVPWLGNTLQFRKEASAVGGQHIL-------FERWAKDFRSDLVGLKLGREYVVVALGHEMVKEVQLQEVFEGRPDNFFLRLRTMGT-----RKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQPIEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICG------GLLAQFPWLRHVAPDRTGYNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYL-QEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERF----IDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSV-----VLPAGESPSMVLLPGITLTPKPYKVQFVKR 503          

Query:  470 GIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELE----TLQGK--RVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPT-TNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            G+   DG+ W  QR F+L+ L +FG  +S   +IV  E   LL++L+       GK  R++  DL  +Y +N +      +R+  G  ++  + +    + K  D++   F   P+   +  +          ++   +++ +  +E++ HR +     E  DL+D +L  Q +     G    F+D  LL + L++ +AG ETT  +L + F+ +     IQ++  +EI  ++G ER P  + DR  L Y +A+  E  R+  +    + HRA+ D+ ++GY +PKD +V +       +   +  P+ F P+R+L    +G +K    E  N FG G+ RC G+ L +   F+F T+++Q F++
Sbjct:  117 GVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPL---LRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM---FSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL---FDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  470 GIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELE----TLQGK--RVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPT-TNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            G+   DG+ W  QR F+L+ L +FG  +S   +IV  E   LL++L+       GK  R++  DL  +Y +N +      +R+  G  ++  + +    + K  D++   F   P+   +  +          ++   +++ +  +E++ HR +     E  DL+D +L  Q +     G    F+D  LL + L++ +AG ETT  +L + F+ +     IQ++  +EI  ++G ER P  + DR  L Y +A+  E  R+  +    + HRA+ D+ ++GY +PKD +V +       +   +  P+ F P+R+L    +G +K    E  N FG G+ RC G+ L +   F+F T+++Q F++
Sbjct:  117 GVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPL---LRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGM---FSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYL---FDGHLKLP--EAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKM 471          

Query:  149 YLCTFLL-GAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISR---THR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDAL 1576
            +LC FLL G  I  K  +  P        P    LP +G LH I+ + I   + +  +++G++F+ R     +++LN Y  VK  ++  G N + R  L        + G+    G  W+ QR F L  L +FG+GK      +  EC  L E +   QG+  D   L++    N+I       RF   D   + +          K++ +  +    I +++  +  W++ R    H+  I  +  V  + +E+V+EHR   D  S   D ID FL +  +LK  T +  GF    L   SL+L +AG ETT+TTL W  L+M KY  IQ KV EEI  ++G  R P+ +DR ++ YT AV+ EI R+ ++AP+ L      D+ I  Y +PK  +V SNL +  FDE  WE P  F P  FL  D  G  K+   +    F +GKR C GE LA+ME F+FF+S++QRF       V  +L
Sbjct:   18 FLCVFLLLGDYIKNKAPKNFP--------PGPWSLPIIGDLHHIDNSKIHLQFTKFAERYGNIFSFRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIVGDKGLILSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINVECGFLNEAISNEQGRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTL---------LKNISEAVYLEGSICNQLYNMFPWLMERLPGPHKTIITLWRKVTDFVREKVNEHRVDYD-PSNPRDYIDCFLTEMEKLKDDTAA--GFDVENLCICSLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQEEIDAVVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIAPINLARSTSEDTQIGNYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFL--DAEG--KFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSL 476          

Query:  149 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL-MSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNI-NDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            +LC FLL +        +   PK     P    LPF+G LH I+   I   +    +K+G +F+ R     +++LN Y  VK  +   G N + R  L ++S +  +N G+    G  W+ QR F L  L +FG+GK      +  EC  L E +   QG+  +   L++    N+I       RF   D   +N+ N +   V  +  +       + +++  P L   ++   H+  I  +  V  + +E+V+EHR   D  S   D ID FL +  + K  T +  GF    L   +L+L +AG ETT+TTL W  L+M KY  IQ KV +EI  ++G  R P+ +DR ++ YT AV+ EI R+ ++ PL +V     D+ I  Y +PK  LV  +L +  FDE  WE P  F P  FL  D  G  K+   +    F +GKR C GE LA+ME F+FFTS++QRF       V     E +L    G  RC K  K     R
Sbjct:   18 FLCVFLLLSDYI-----KNKAPKNFP--PGPWSLPFIGDLHHIDPNKIHLQFTEFAEKYGKIFSFRLFGSRIVVLNGYNLVKEVYTQQGDNLADRPTLPITSAIIGDNRGLVASSGYKWKHQRRFALTTLRNFGLGKKNLELSINFECGFLNEAISNEQGRPFNPRLLLNNAVSNVICVLVFGNRFEYSDHHFQNLLNKINESVYLEGSIF------VHLYNMFPWLMQ-LLPGPHKKLITLWQRVTDFVREKVNEHRADYD-QSSLRDYIDCFLAEMEKHKDDTAA--GFDVENLCMCTLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQQEIDAVVGSSRQPSGSDRDNMPYTNAVIHEIQRMGNIIPLNVVRTTSEDTRIEKYSIPKGTLVIGSLTSVLFDESEWETPHSFNPGHFL--DAEG--KFRRRDAFLPFSLGKRVCLGEQLARMELFLFFTSVLQRFTFSPPAGV-----EPSLDFKMGFTRCPKPYKLCAVPR 497          

Query:  149 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL-MSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNI-NDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            +LC FLL +        +   PK     P    LPF+G LH I+   I   +    +K+G +F+ R     +++LN Y  VK  +   G N + R  L ++S +  +N G+    G  W+ QR F L  L +FG+GK      +  EC  L E +   QG+  +   L++    N+I       RF   D   +N+ N +   V  +  +       + +++  P L   ++   H+  I  +  V  + +E+V+EHR   D  S   D ID FL +  + K  T +  GF    L   +L+L +AG ETT+TTL W  L+M KY  IQ KV +EI  ++G  R P+ +DR ++ YT AV+ EI R+ ++ PL +V     D+ I  Y +PK  LV  +L +  FDE  WE P  F P  FL  D  G  K+   +    F +GKR C GE LA+ME F+FFTS++QRF       V     E +L    G  RC K  K     R
Sbjct:   18 FLCVFLLLSDYI-----KNKAPKNFP--PGPWSLPFIGDLHHIDPNKIHLQFTEFAEKYGKIFSFRLFGSRIVVLNGYNLVKEVYTQQGDNLADRPTLPITSAIIGDNRGLVASSGYKWKHQRRFALTTLRNFGLGKKNLELSINFECGFLNEAISNEQGRPFNPRLLLNNAVSNVICVLVFGNRFEYSDHHFQNLLNKINESVYLEGSIF------VHLYNMFPWLMQ-LLPGPHKKLITLWQRVTDFVREKVNEHRADYD-QSSLRDYIDCFLAEMEKHKDDTAA--GFDVENLCMCTLDLFVAGTETTSTTLYWGLLYMIKYPEIQAKVQQEIDAVVGSSRQPSGSDRDNMPYTNAVIHEIQRMGNIIPLNVVRTTSEDTRIEKYSIPKGTLVIGSLTSVLFDESEWETPHSFNPGHFL--DAEG--KFRRRDAFLPFSLGKRVCLGEQLARMELFLFFTSVLQRFTFSPPAGV-----EPSLDFKMGFTRCPKPYKLCAVPR 497          

Query:  149 YLCTFLL-GAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDK----LRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISR---THR--IKHFDAVHKYFQEEVDEHRKSLD-LNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDAL 1576
            +LC FLL G  I  K  +  P        P    LP +G LH I+ + I   + +  +++G++F++R     +++LN Y  VK  ++  G N + R  L        + GI    G  W+ QR F L  L +FG+GK      +  EC  L E +   QG+  D   L++    N+I       RF   D      L++IN+ I             +    I  ++  +  W++ R   +H+  I  +  V  + +++V+EH+   D LN    D ID FL +  +LK  T +  GF    L   +L+L +AG ETT+TTL W  L+M KY +IQ KV EEI  ++G  R P+ +DR ++ YT AV+ EI R+ ++ P+ +      D  I  Y VPK  +V SNL +  FDE  WE P  F P  FL    N + K+   +    F +GKR C GE LA+ME F+FF+S++QRF       V  +L
Sbjct:   18 FLCVFLLLGDYIKNKAPKNFP--------PGPWSLPIIGDLHHIDNSKIHLQFTKFAERYGNIFSLRLFGPRIVVLNGYNLVKEVYIKQGDNLADRPVLPLFYEIIGDKGIVLSSGYKWKHQRRFALSTLRNFGLGKKSLEPSINLECGFLNEAISNEQGRPFDPRLLLNNAVSNVICVLVFGNRFDYSDHHFQTLLKHINEAI-------------YLEGGICAQLYNMFPWLMQRLPGSHKKVITLWKKVIDFIRQKVNEHKVDHDPLNPR--DYIDCFLAEMEKLKDDTAA--GFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPVIQAKVQEEIDRVVGGSRHPSVSDRDNMPYTNAVIHEIQRMGNIIPINVTRTTSEDIRIGKYSVPKGTMVTSNLTSVLFDESEWETPHSFNPGHFL----NAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSL 476          

Query:  224 RRIPTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVS-DALYEEALIG 1597
            +  P  K LP VG L  ++ T  F  + +L K +G+VF V  G    ++L  Y+TVK A V+    +  R       +  +  GI F +G+NW+  R F L  L DFGMGK  S E + +E  +L  E +  +GK  D +  ++    NIIS      RF   D +   + D      +    +  W     ++D  P L  ++ ++   +++         + +    ++L+ N +    +D FLI++   + S      F +  L+     L IAG +TT TTL W  + M+KY  IQ +V EEI  +IG  R P   DRK L YT AV+ EI R++++ PL+L HR  +D + NGY++ K   V   L +   DE  WEKP  FYPE FL  D  G  ++   +    F  G+R C GESLA+ME F+FFTS++Q +       VS D L  + ++G
Sbjct:   43 KEPPGPKPLPLVGNLLTLDLTRPFDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMW-----LYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPN-DPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGG-RQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFL--DEKG--QFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVG 491          

Query:  248 LPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPI---FDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIG 1597
            LP +G LH   ++ P     E L KK+GSVF+V+ G   V++L  Y  VK A ++    +S R  + +    +N  GI F  G+NW+  R F L  L DFGMGK    + + +EC +L+E  ++ +G+  + S +++    NII    +  RF   D  L  +  LI  +A+            PI   ++  P +  W+    H + K+    H + +E   EH+  LD+N +  D ID FLIKQ + K++TG    F +  L+ +   L  AG+ETT+TTL WS + M KY  IQ+KV EEI  +IG  + P    RK + YT AV+ EI R + + P  L H    D +  GY +PK   V   L +   D+  +E+P EFYP+ FL ++ N    +  NE    F  GKR CAGE+LAKME F+FFT ++Q F   F       L+   L+G
Sbjct:   39 LPLIGNLHIMNLKKPYMTLME-LGKKYGSVFSVQLGTEKVVVLCGYDAVKDALINHAEEFSDRPIIEAFHRRSNGHGITFSHGENWKVMRRFTLATLRDFGMGKRTIEDKINEECISLVETFQSYKGEPFENSLILNAAVANIIVSILLGHRFEYQDPTLLKLIRLINEIAR--------ILGTPIVMLYNAYPSVMRWLPGSHHNVEKNTQKSHTFIKETFAEHKAQLDINDQ-RDFIDAFLIKQSEEKSATGRF--FHNENLVSLVDSLFSAGMETTSTTLRWSLMLMMKYPEIQKKVQEEIDKVIGSAQ-PQMEHRKQMPYTDAVIHEIQRFADIVPTNLPHSTTKDVTFRGYLIPKGTQVIPLLTSVLRDKAYFERPYEFYPQHFLDSEGN----FVKNEAFIPFSAGKRSCAGETLAKMELFLFFTKLLQNF--TFQSPPGQDLHLTPLVG 475          

Query:  248 LPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPI---FDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIG 1597
            LP +G LH   ++ P     E L KK+GSVF+V+ G   V++L  Y  VK A ++    +S R  + +    +N  GI F  G+NW+  R F L  L DFGMGK    + + +EC +L+E  ++ +G+  + S +++    NII    +  RF   D  L  +  LI  +A+            PI   ++  P +  W+    H + K+    H + +E   EH+  LD+N +  D ID FLIKQ + K++TG    F +  L+ +   L  AG+ETT+TTL WS + M KY  IQ+KV EEI  +IG  + P    RK + YT AV+ EI R + + P  L H    D +  GY +PK   V   L +   D+  +E+P EFYP+ FL ++ N    +  NE    F  GKR CAGE+LAKME F+FFT ++Q F   F       L+   L+G
Sbjct:   73 LPLIGNLHIMNLKKPYMTLME-LGKKYGSVFSVQLGTEKVVVLCGYDAVKDALINHAEEFSDRPIIEAFHRRSNGHGITFSHGENWKVMRRFTLATLRDFGMGKRTIEDKINEECISLVETFQSYKGEPFENSLILNAAVANIIVSILLGHRFEYQDPTLLKLIRLINEIAR--------ILGTPIVMLYNAYPSVMRWLPGSHHNVEKNTQKSHTFIKETFAEHKAQLDINDQ-RDFIDAFLIKQSEEKSATGRF--FHNENLVSLVDSLFSAGMETTSTTLRWSLMLMMKYPEIQKKVQEEIDKVIGSAQ-PQMEHRKQMPYTDAVIHEIQRFADIVPTNLPHSTTKDVTFRGYLIPKGTQVIPLLTSVLRDKAYFERPYEFYPQHFLDSEGN----FVKNEAFIPFSAGKRSCAGETLAKMELFLFFTKLLQNFT--FQSPPGQDLHLTPLVG 509          

Query:  233 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1540
            P  K LP +G +H I  + P   Y E L KK+G +F V+ G + +++L  Y+TVK A V+    +S R  +   L      GI F  G+NW+  R F L  L DFGMG+    + + +EC  L+E+ ++ +GK  D + +++    NII    +  RF   D K   +  LI      ++L       + +++  P +  W+      + K+     ++ +E   +H++ LD+N +  +L+D FL+KQ + K   G+   F D  L  +   L +AG+ETT+T++ W  L M KY  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LAKME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLI-----NENLRLTGSPTVMLYNVFPSVMRWLPGNHQTVGKNAAENQRFIRETFIKHKEKLDVNDQ-RNLVDAFLVKQQEKK---GNAVYFHDDNLTMLVSNLFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLAKMELFLFFTSLLQNF 459          

Query:  233 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDD----KLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1540
            P  K LP +G +H I  + P   Y E L KK+GS+F+V+ G + +++L  Y+TVK A V+    +S R  +   L A    G+ F  G+NW+  R F L  L DFGMG+    + + +EC  L+E+ ++ +GK  D + +++    NII    +  RF   D      +  IN+ +      K +L         ++  P +  W+      + K+    H++ +E   ++R  LD+N +  +L+D FL+KQ +     G+   F D  L  +   L +AG+ETT+T++ W  L M K+  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LA+ME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGSIFSVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVIPIFLDAVKEYGVIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPIFLRLMSLINENVRLTGSPKAML---------YNVFPSVMRWLPGNHQTVGKNAAEYHRFIRETFTKYRDKLDINDQ-RNLVDAFLVKQQE---KNGNAVYFHDDNLTVLVSNLFVAGMETTSTSVRWGLLLMMKFPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNF 459          

Query:  233 PTEKGLPFVGVLHQI--ETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1540
            P  K LP +G +H I  + P   Y E L KK+G +F V+ G + +++L  Y+TVK A V+    +S R  +   L      GI F  G+NW+  R F L  L DFGMG+    + + +EC  L+E+ ++ +GK  D + +++    NII    +  RF   D K   +  LI      ++L       + +++  P +  W+      + K+     ++ +E   +H++ LD+N +  +L+D FL+KQ + K   G+   F D  L  +   L +AG+ETT+T++ W  L M KY  IQ+ V  EI  +IG+ R P T  RK + YT AV+ EI R  ++ P+ L H    D +  GY++PK   V   L +  +D+  +EKPKEFYP+ FL ++ N    +  NE    F  GKR CAGE+LA+ME F+FFTS++Q F
Sbjct:   36 PGPKPLPIIGNIHNINLKRPYLTYLE-LWKKYGPIFRVQIGSQKMVVLCGYETVKDALVNYAEEFSERPVVPIFLDVVKEYGIIFSHGENWKVMRRFTLSTLRDFGMGRRTIEDRINEECDFLVEQFKSFKGKPFDNTMIMNAAVANIIVSIVLGHRFDYQDPKFLRLMSLI-----NENLRLTGSPTVMLYNVFPSVMRWLPGNHQTVGKNAAENQRFIRETFIKHKEKLDVNDQ-RNLVDAFLVKQQEKK---GNAVYFHDDNLTMLVSNLFVAGMETTSTSVRWGLLLMMKYPEIQKNVQNEIEKVIGQSR-PQTEHRKSMPYTDAVIHEIQRFGNIIPMNLPHATAQDVTFRGYFLPKGTFVIPLLTSVLYDQTRFEKPKEFYPQHFLDSEGN----FVKNEAFLPFSAGKRSCAGENLARMELFLFFTSLLQNF 459          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSD 1570
            P  K LP +G L Q+ +  +     +L K++GSVF V  G R VI+L+ YQTVK A VD G  +SGR            +GIAF DG+ W+  R F +++L +FGMGK    E + +E   LLE L  ++GK  D   ++     NII       RF   D++L  I   I           F   + P   +++  P + DWI     R+ ++F  +       V EH+ SLD NS   D ID FL K  Q K     +  F    LL  +  LL  G ET  TTL  +FL + KY  +Q +V EEI  ++G+ R PT  DR  + YT AV+ E+ R + V P+ L HR   D+   G+ +PK   V + L   H+D   ++ P+EF PE FL    + +  +  +     F  G+R C GE LA+ME FI+FTSI+Q F ++   D  D
Sbjct:   32 PGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFIND--------NFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMAQEKQD--PLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFL----DDNHSFKKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPED 467          

Query:  185 WKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIET-PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLI--THVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRM---SLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1549
            WK T      KG +  P    +PF+G   Q+ T   F+ +++L KK+GSVF V +G R V++L  ++ VK A VD   ++SGR  + +        G+A  +G+ W+  R F L VL +FGMGK    E +++E   LLEEL  ++G  +D +  +     N+I      KRF   D + +++  +I  + V   K   Q +     +    P   +++ +    +K F A        V  +  S D  S   D ID FLIK HQ K+     +  T+F L  +   +L L  AG ET ++TL + FL + KY  ++ K+HEEI  +IG  R P  +DR  + YT AV+ EI R++ + PL + H    D+   GY +PK   V+    +   D K +  P  FYP+ FL  D  G  ++  N+    F  GKR C GE+LA+ME F++FTSI+QRF +R
Sbjct:   24 WKRTS-----KGGKLPPGPTPIPFLGNFLQVRTDATFQSFQKLQKKYGSVFTVYFGPRPVVVLCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTLYLSRTVSNVICSVVFGKRFDYQDQRFQSLMRMINESFVEMSKPWAQLYDMYWKVMQYFPGRHNYLYNLIEDLKDFIA------SRVKINEASFD-PSNPRDFIDCFLIKMHQDKS-----DPHTEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLLKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVTRDTHFRGYLLPKGTDVYPLFGSVLKDPKYFRYPDAFYPQHFL--DEQG--RFKKNDAFVVFSSGKRICVGEALARMELFLYFTSILQRFSLR 463          

Query:  287 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHK-----------YFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            + + + +L +KHG VF V  G R V++L   QT++ A VD    +SGR  + ++ L   + GI F  GQ W+T R F L  + +FGMGK    E +++E   L+EEL+  QG  +D + L    T NII      +RF   DD+  ++ +L+  +           F L  F                +K+F  VH+           Y    V++H+ +LD  S   D ID +L++  + K++  +   F    L+   L L  AG ETT+ TL +  L M KY  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R S + P+ L H+ + D+   GY +PK+  V+  L +   D + +E+P +F PE FL  D NG +K    E    F  GKR C GES+A+ E FIFFT+I+Q F V
Sbjct:   51 LLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFEL--FSGF-------------LKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLD-PSAPRDYIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFL--DANGALKKC--EAFLPFSTGKRICLGESIARNELFIFFTTILQNFSV 459          

Query:  287 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            + + +  L +KHG VF V  G R V++L   QT++ A V++   +SGR  + ++ L   + GI F  G+ W+T R F L  + +FGMGK    E +++E   L+EEL+  QG  +D +      T NII      +RF   D++   + +L+  +     LL+   F+  +F+    L  +      +I K+   +  +    V++HR +LD  SE  D ID +L++  + K++  +   F    L+   L L  AG ETT+TTL   FL M  Y  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R S + P    HR   D+   GY +PK+  V+  L +   D + +E+P  F P+ FL  D NG +K   +E    F  GKR C GES+A+ E F+FFTSI+Q F V
Sbjct:   51 LLKCFIHLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQDYGIFFSSGERWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGAPLDPTFFFQCVTANIICSIVFGERFDYTDEQFLRLLNLMYQIY---SLLRS--FSCQMFELFSGLLKYFPGVHRQIAKNQQEILNFITHRVEKHRATLD-PSEPRDFIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSTTLCCGFLLMLMYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDIVPTGAPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFL--DANGALK--KSEAFLPFSTGKRICLGESIARNELFLFFTSILQNFSV 459          

Query:  233 PTEKGLPFVGVLHQIET-PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFAL--PIFDKMPLLCDWIISRTHR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            P  + LPF+G L Q++   +   + +L +K+G VF V  G R V++L    T++ A V+    +SGR  +          G+ F  G+ W+T R F L  + DFGMGK    E +++E   L+EEL+  +G  ++ +        NII      +RF   D +  ++ +LI         L    F L   I    P          HR   K+   +  Y    V++HR +LD  S   D ID +L++  + K++  +   F    L+   L L  AG ETT+TTL +SFL M KY  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R + +AP+ L H+   D+   GY +PK+  V+  L +   D + +E+P  F PE FL  D NG +K   NE    F  GKR C GE +A+ E F+FFT+I+Q F +
Sbjct:   33 PGPRPLPFLGNLLQMDRRGLLSSFIQLQEKYGDVFTVHLGPRPVVMLCGTDTIREALVNQAEAFSGRGTVAVLDPIVQGYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYKGAPLNPTFYFQCIVANIICSIVFGERFDYKDHQFLHLLNLIYQTFSLMSSLSSQVFELFSAILKYFP--------GAHRQISKNLQEILDYIGHSVEKHRATLD-PSAPRDFIDTYLLRMEKEKSNHHT--EFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFTDLAPIGLPHKVTKDTLFRGYLIPKNTEVYPILSSALHDPRYFEQPDSFNPEHFL--DANGALK--TNEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSL 460          

Query:  215 KGLRRIPT-EKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1549
            KG  R+P   + LPF+G L Q+ +  +     +L K+ G+V+ V  G R V++L+ YQ VK A VD    +SGR    +       +GIAF +G  W+  R + L++L +FGMGK    E + +E   LLEEL   QGK  D + ++     NII       RF   DD+L  I  LI           F   + P   +++  P L DW+     R+ K++  +       V EH+ SLD NS   D ID FL K  Q K    S   F D  LL  +  LL  G ET  TTL  +F  + KY  +Q +V EEI  ++G+ER PT  DR ++ YT AV+ E+ R + + P++L HR   D++  G+ +P+   V + L   H+D   + KPKEF PE FL    + ++ +  +     F  G+R C GE+LA+ME F++ T+I+Q F ++
Sbjct:   25 KGKGRLPPGPRALPFLGNLLQLRSQDMLTSLTKLSKEFGAVYTVYLGPRRVVVLSGYQAVKEALVDQAEEFSGRGDYPAFFNFTKGNGIAFSNGDRWKALRKYSLQILRNFGMGKRTIEERILEEGHFLLEELRKTQGKPFDPTFVVSRSVSNIICSVIFGSRFDYDDDRLLTIIHLINE--------NFQIMSSPWGEMYNIFPNLLDWVPGPHRRLFKNYGRMKNLIARSVREHQASLDPNSP-RDFIDCFLTKMAQEKQDPLS-HFFMD-TLLMTTHNLLFGGTETVGTTLRHAFRLLMKYPEVQVRVQEEIDRVVGRERLPTVEDRAEMPYTDAVIHEVQRFADIIPMSLPHRVTRDTNFRGFTIPRGTDVITLLNTVHYDPSQFLKPKEFNPEHFL----DANMSFKKSPAFMPFSAGRRLCLGEALARMELFLYLTAILQSFSLQ 460          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSD 1570
            P  K LP +G L Q+ +  +     +L K++GSVF V  G R VI+L+ YQTVK A VD G  +SGR            +GIAF DG+ W+  R F +++L +FGMGK    E + +E   LLE L  ++GK  D   ++     NII       RF   D++L  I   I           F   + P   +++  P + DWI     R+ ++F  +       V EH+ SLD NS   D ID FL K  Q K     +  F    LL  +  LL  G ET  TTL  +FL + KY  +Q +V EEI  ++G+ R PT  DR  + YT AV+ E+ R + V P+ L HR   D+   G+ +PK   V + L   H+D   ++ P+EF PE FL    + +  +  +     F  G+R C GE LA+ME FI+FTSI+Q F ++   D  D
Sbjct:   32 PGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFIND--------NFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMAQEKQD--PLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFL----DDNHSFKKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPED 467          

Query:  185 WKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIET-PIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRIKHF-DAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVR 1549
            WK T R     G +  P    +PF+G L Q+     F+ + +L KK+GSVF V +G R V+IL  ++ VK A VD   ++SGR  + +        G+A  +G+ W+  R F L VL +FGMGK    E +++E   LLEEL  ++G  +D +  +     N+I      KRF   D + R++  +I           F   ++P   ++D    +  +   R +R+ +  + +  +    V  +  S D  S   D ID FLIK +Q K+   S   F    L+  +L L  AG ET ++TL + FL + KY  ++ K+HEEI  +IG  R P  +DR  + YT AV+ EI R++ + PL + H  + D+   GY++PK   V+  + +   D K +  P+ FYP+ FL  D  G  ++  N+   AF  GKR C GE+LA+ME F++FTSI+QRF +R
Sbjct:   24 WKRTSR-----GGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINE--------SFVEMSMPWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFD-PSNPRDFIDCFLIKMYQDKSDPHS--EFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFL--DEQG--RFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLR 463          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            P  K LP +G L Q+ +  +     +L K +GSVF V  G R VI+L+ YQTVK A VD G  +SGR            +GIAF DG+ W+  R F +++L +FGMGK    E + +E   LL+ L   +GK  D   ++     NII       RF   D++L  I   I           F   + P   +++  P L DW+     R+ ++F  +       V EH+ SLD NS   D ID FL K  Q K     +  F    LL  +  LL  G ET  TTL  +FL + KY  +Q +V EEI  ++G+ R PT  DR  + YT AV+ E+ R + V P+ L HR + D+   G+ +PK   V + L   H+D   ++ P+EF PE FL    + +  +  +     F  G+R C GE LA+ME FI+ TSI+Q F +
Sbjct:   32 PGPKPLPILGNLLQLRSQDLLTSLTKLSKDYGSVFTVYLGPRRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLDVLRKTEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHFIND--------NFQIMSSPWGEMYNIFPSLLDWVPGPHRRVFRNFGGMKDLIARSVREHQDSLDPNSP-RDFIDCFLTKMVQEKQD--PLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFL----DANQSFKKSPAFMPFSAGRRLCLGEPLARMELFIYLTSILQNFTL 459          

Query:  287 IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHK-----------YFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            + + + +L +KHG VF V  G R V++L   QT++ A VD    +SGR  + ++ L   + GI F  GQ W+T R F L  + +FGMGK    E +++E   L+EEL+  QG  +D + L    T NII      +RF   DD+  ++ +L+  +           F L  F                +K+F  VH+           Y    V++H+ +LD  S   D ID +L++  + K++  +   F    L+   L L  AG ETT+ TL +  L M KY  + +KV +EI  +IG  R PT +DR  + YT AV+ EI R S + P+ L H+ + D+   GY +PK+  V+  L +   D + +E+P +F PE FL  D NG +K    E    F  GKR C GES+A+ E FIFFT+I+Q F V
Sbjct:   51 LLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFEL--FSGF-------------LKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLD-PSAPRDYIDTYLLRMEKEKSNHNT--EFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFL--DANGALKKC--EAFLPFSTGKRICLGESIARNELFIFFTTILQNFSV 459          

Query:  182 FWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            F+ F +R  IPKGL+  P E GLP +G++H+I+ P+  Y  +L KKHG +F ++ GMRDV+IL++Y  +K A VDDG N+SGRWR+    L  ++SGI F DGQ+W TQR+F+LKVL DFG+GKS S ++V+ EC  LLEELE+L+GK +D S +I +YT NIISKF MNKRF R + K+  I  +++   K+KD++Q      P  D   L C+ II+ T + K F  +  YF+EE+DEH K++D NSEGEDL+DRFLIKQ+QLK     +  F D+QL+R SLEL  AG ETT+TTL WSFLFMSK+  IQQKVH EI+ IIGKER PT ND+K +NYTQAVMDEIFR+SSVAPLAL+HR +ND++I+GY++PK+ L+F NLYACHFD  +WEKP  FYPE FL+ D NG++KYT  + L  F +GKR+C GESLA+ME FIFFTSI+QRF V+  +++++  YEEAL+G DG++R S +N FIFTK+
Sbjct:   17 FYGFQKRNSIPKGLKETPIEYGLPILGIIHKIKEPMHNYLLKLSKKHGPIFRIKLGMRDVLILSNYDIIKKALVDDGQNFSGRWRMKLISLITHDSGIIFKDGQDWSTQRSFVLKVLRDFGLGKSKSVDLVQNECSFLLEELESLEGKIIDFSKIIPIYTANIISKFIMNKRFERENPKIARIEKMLSEEIKKKDIIQLLHIMFPKCDTSGLFCELIINFTSKWKEFLEIQNYFKEEIDEHLKTIDFNSEGEDLMDRFLIKQNQLKQQNIDVGSFNDWQLIRSSLELFYAGYETTSTTLCWSFLFMSKHQDIQQKVHNEIIEIIGKERLPTMNDKKSMNYTQAVMDEIFRMSSVAPLALIHRTLNDANIDGYFIPKNTLIFPNLYACHFDRDIWEKPMIFYPEHFLTEDDNGNLKYTPRDELILFSIGKRQCLGESLARMEFFIFFTSILQRFRVKLVKELNEKEYEEALLGKDGIIRGSIVNDFIFTKQ 506          

Query:  164 LLGAAIFW----KFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIF 1642
            + G  I W    +  +R  IP GL+  P E G P +G++ +I+ P+  Y   L +KHG +F +R GMRDV+IL +YQT++ A VDD   +SGRW++    +  ++SGI F DG  W TQR+F+LKVL DFGMGKS+S +IV+ EC  LL EL++LQG+ +D S +I +YT NIISKF MNKRF R D +++ I   I   +KQ D++Q      PIFDK  ++  + +  T +++ F  V + F +E++EH+ +LD NSEG+DLIDRFL++Q++L  STG +E FTD QL+ M+ E+  AG ETT+TTL WS LFMS+Y  IQ+KV+EEI+N+IG+ER PT ND+K LNYTQAVMDEI R+SSVAPL + HR  ND+S++ Y++PK++LVF+N YACH D  +W KP EFYPE FL    N ++KY+  E L  FG+GKR+C GESLA+ME FIFF SI+QR++V F+E++SD+L+EE L GN+G++R SKI  FIF
Sbjct:    7 IFGLFIIWYCFSRVFKRRSIPNGLKETPIEYGWPILGIIPKIKGPMQNYLLELSRKHGPIFRIRLGMRDVVILGNYQTIRKALVDDAQIFSGRWKMKLVSVVTHDSGIVFKDGPVWSTQRSFILKVLRDFGMGKSISQDIVQGECLFLLNELDSLQGEIIDFSKIIPIYTANIISKFIMNKRFDRSDPRIKFIEYAIFQTSKQSDIVQRLHLMFPIFDKSTIISKFNLWITSKLQLFSKVERVFHDEIEEHKTNLDYNSEGDDLIDRFLLEQNRLSQSTGIVESFTDKQLIFMTFEMFGAGYETTSTTLGWSMLFMSRYKDIQKKVYEEILNVIGEERMPTMNDKKSLNYTQAVMDEILRLSSVAPLGIFHRTFNDTSVDNYFIPKNSLVFANYYACHTDPDIWLKPVEFYPEHFLIKCENDELKYSPREELIPFGIGKRQCIGESLARMEYFIFFVSILQRYQVDFSENISDSLFEETLRGNEGIIRYSKIKNFIF 503          

Query:  161 FLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK--QKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVS 1567
            ++L    FW   R    P G R       LP +G LH   ++ P +R Y +L K +G VF+V+ G+R +++++ Y+TVK A V+    +S R ++         +G+ F  G+NW+  R F L  L DFGMGK V  + + +E  +L + +E+ +GK  DAS +I+    NII    + KRF   D +   + DL     +   K L+        +++  P L   + +  + +++ D  H Y Q    EH K+LD N +    ID FL+KQ + K++T     F +  LL +   L  AG+ET +TTL W FL M KY  IQ+KV EEI  +IG    P    R  + YT AV+ EI R +++ PL L H    D ++ GY++PK   +   L +   D+  WEKP  FYPE FL  D NG  K+   +    F  G+R CAGE+LAKME F+FFTS++QRF       VS
Sbjct:   14 YILKVGGFWNNHRNKNFPPGPR------PLPIIGNLHLFDLKRP-YRTYLQLSKIYGPVFSVQMGLRKIVVISGYETVKEALVNQADAFSERPKIPVFEDLTRGNGVVFAHGENWKVMRRFTLTTLRDFGMGKRVIEDRIVEEYRHLADIIESQEGKPFDASKMINAAVANIIVSILLGKRFDYKDSRFVRLQDLTNESMRLAGKPLVT-------VYNIFPHLGFLLRANKNLLRNRDEFHAYVQVTFVEHLKTLDKNDQ-RSFIDAFLVKQQEEKSTTNGY--FHNGNLLSLVSNLFTAGVETISTTLNWGFLLMLKYPEIQRKVQEEIERVIGSNP-PRIEHRTQMPYTDAVIHEIQRFANILPLDLPHETAADVTLKGYFIPKGTYIIPLLASVLQDKSQWEKPDMFYPEHFL--DANG--KFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFHPPPGVS 464          

Query:  149 YLCTFL--LGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK--QKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDA 1573
            ++ TFL  L    FW   RR   P G R       LP +G LH   ++ P +R Y +L K +G VF+V+ G++ +++++ Y+TVK A V+    ++ R ++         +GI F  G+NW+  R F L  L DFGMGK    + + +E   L++ + + +GK  DAS +IH    NII    + KRF   D +   +  L     +   K L+        +++  P L   + +    ++  +  H Y Q    EH K+LD N +   LID FL+KQ + K++T     F +  LL +   L  AG+ETT TTL WSFL M KY  IQ+KV EEI  +IG    P    R  + YT AV+ EI R +++ PL L H    D ++ GY++PK   V   L +   D+  WEKP +FYPE FL  D  G  ++   +    F  G+R CAGE+LAKME F+FFTS++QRF       VS +
Sbjct:   12 FILTFLSILKMGHFWNNHRRKNFPPGPR------ALPIIGSLHLFDLKRP-YRTYLQLSKLYGPVFSVQMGLKKIVVISGYETVKEALVNQADAFAERPKIPIFQDLTGGNGIIFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLVDNIGSQEGKPFDASKIIHAAVANIIVSILLGKRFDYKDSRFVRLLHLTNESMRLAGKPLVT-------MYNIFPYLGFLLRANKTLLQIKEEFHAYVQVTFVEHLKTLDKNDQ-RSLIDAFLVKQQEEKSTTNGY--FHNGNLLNLVSNLFTAGVETTATTLNWSFLLMLKYPEIQRKVQEEIEQVIGSNA-PRIEHRTHMPYTDAVIHEIQRFANILPLDLPHETTEDVTLRGYFIPKGTYVIPLLTSVLQDKSQWEKPDKFYPEHFL--DAKG--RFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFTFHPPPGVSTS 470          

Query:  161 FLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLH--QIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK--QKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDA 1573
            ++L  A FW   +R   P G R       LP +G LH   ++ P +R Y +L K++G VF+V+ G R V++++ Y+TVK A V+    ++ R ++         +G+ F  G+NW+  R F L  L DFGMGK    + + +E   L + + + QGK  DAS +I+    NII    + KRF   D +   + +L     +   K L+        +++  P L   + +    +++ D  H Y +    EH K+LD N +   LID FL+KQ + K++T     F +  LL +   L  AG+ET +TTL W FL M KY  IQ+KV EEI  +IG    P    R  + YT AV+ EI R +++ PL L H    D ++ GY++PK   +   L +   DE  WEKP  FYPE FL  D NG  K+   +    F  G+R CAGE+LAKME F+FFTS++QRF       VS +
Sbjct:   17 YILKIAGFWDNNQRKNFPPGPR------ALPIIGNLHLFDLKRP-YRTYAQLSKEYGPVFSVQMGHRKVVVISGYETVKEALVNQADAFAERPKIPVFEDLTKGNGVVFAHGENWKVMRRFTLTTLRDFGMGKRAIEDRIVEEYGYLGDTIASQQGKPFDASKIINAAVANIIVSILLGKRFDYKDSRFVRLLNLTNESVRLAGKPLVT-------MYNIFPYLGFLLRANKSLLQNRDEFHDYVKVTFVEHLKNLDKNDQ-RSLIDAFLVKQQEEKSTTNGY--FHNGNLLSLMSNLFTAGVETISTTLYWGFLLMLKYPEIQRKVQEEIDQVIGSNP-PRIEHRTQMPYTDAVVHEIQRFANILPLDLPHETAADVTLKGYFIPKGTYIIPLLTSVLRDESQWEKPDVFYPEHFL--DANG--KFVKKDAFMPFSAGRRICAGETLAKMELFLFFTSLLQRFNFLPPPGVSTS 469          

Query:  245 GLPFVGVLHQIETPIFR-YYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR-WRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKIN 1630
             LPF+G +  I +P    Y  +L K + ++F++R G + +I+L  Y+ VK A V+   N+  R +  ++  + + N G+   +G  W+ QR F L  L +FG+GK      + +E   LL+E++  +G+  D S L +    NII +    +R+   D    +   ++ + ++   L    +  L  ++  P +   +  R + I  +++ + ++ ++ +D+H+ +LD  S   D +D FLI++     S    +GF+D  L+R +L+L +AG ETTTT+L W+ ++++K   IQ KV EEI  +IG+ R P   D+ ++ YT+AV+ EI R   + PL+    A  D+++ GY +PK   +   L++  FDE  WE P  F P+ FL  D  G  K+   +   AF  GKR C GE LA+ME F+FFT + Q+F  RF+E   + L  E ++G     R  KI+
Sbjct:   43 ALPFLGNILDIASPQPHIYLTKLGKAYNNIFSMRIGQQKMILLTGYKMVKEALVNQTDNFVDRPYSPLAERIYSGNGGLFTSNGNLWKKQRRFALSTLRNFGLGKKTMELAICEESHFLLDEMDRHKGQAFDPSGLFNNAVSNIICQLVFGQRYDYAD---YDFQQMLKYTSEAIHLEGSIWGRL--YESFPNIMKHLPGRHNVIFSNYEHISEFIKKNLDKHKANLD-PSNPRDYMDSFLIEKEN---SHDPADGFSDKNLVRCTLDLFLAGTETTTTSLGWALIYLAKNPEIQDKVQEEIDRVIGQSRQPGMADKPNMPYTEAVIHEILRRGDIVPLSGPRVAAKDTTLGGYAIPKGTTIMPILHSVLFDEDEWETPNSFNPQHFL--DKEG--KFVRRDAFLAFSAGKRVCLGEQLARMELFLFFTCLFQKF--RFSEVEGEELDTEGILGVTLTPRPYKIH 492          

Query:  149 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVR-YGMRDVIILNDYQTVKSAFVDDGSNYSGR--WRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISR---THR--IKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLI---KQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDAL 1576
            + C FLL          R   P+     P    LPF+G LH I+T  I   +    +K+G++F+++ +G R V++ N Y+ VK  +V+ G +++ R  + L   +    + G+    G  W+ QR F L  L +FG+GK      +  EC  L+E +   QG R +   LI+    N+I       RF   + + +++  ++          Q ++    I+ +M  +   I+ R    H+  I+ +  V  Y + +VDEH+   D  S   D ID FL    K+   KA+  SIE      L   +++L IAG ETT+TTL W  L+M+KY  IQ KVH EI  ++G  R P+  DR +L YT AV+ EI R+ ++ P  L      D  I  Y +PK A VF NL +  FDE  WE PK F P  FL    N D  +   E    F  GKR C GE LA+ME F+FF+S++QRF  +  E V  +L
Sbjct:   19 FFCVFLLLVEYL-----RNKAPRNFP--PGPPTLPFIGNLHTIDTTRIHLQFIEFAEKYGNLFSIQIFGPRAVVV-NGYKLVKELYVNQGDHFADRPVFPLFHDIF--KDKGLVASSGYAWKQQRRFALTTLRNFGLGKKSLEPSILLECRYLIEAMSNEQGNRFNPQFLINNAVSNVICVLVFGSRFEYSNSEFQDLLKMMN---------QAFYLEGTIWAQMYNMVPRIMRRLPGPHQRVIQLWGNVFNYVRAKVDEHKMDRDF-SNPRDYIDCFLEEMEKRKDDKAADFSIE-----NLCFCAMDLFIAGTETTSTTLYWGLLYMTKYPEIQAKVHAEIDQVVGSSRQPSMMDRDNLPYTNAVIHEIQRMGNIIPFNLARATSKDVQIGEYTIPKGASVFGNLTSVLFDETEWETPKSFNPGHFL----NNDGSFRRREAFMPFSAGKRVCLGEQLARMELFLFFSSLLQRFTFKPPEGVEPSL 477          

Query:  224 RRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFID-GQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALP---IFDKMPLLCDWIISRTHRIKH-FDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCS 1621
            R  P  K L FVG + Q       +  R + K+G + ++  G +  IILN  Q  K AFV +G+ +SGR  L          GI     G +W+ QR F L  L DFG+GK    E V +E   L++E+   +GK       I     NII       RF   D +   + ++I    +        F   P   IF+ +P++  +      +I H   ++ K+  EEV++HRKSLD  +   D ID +L++ ++ +++  S   F +  +LR + +L IAG ETT  TL W  ++M ++  +Q++ HEEIV ++G +RFP+ +DR  L YT A + EI R +++ PL +VH+    + + GY++P    + SNL A   D+  W+ P  F PE FL  D  G  ++  N++   F +G R C GE+LA+ E FIFFTS++Q+ +  + +          + G  GLVR +
Sbjct:   38 RSPPGPKPLLFVGNMPQFIKDKMGFI-RSMPKYGEISSLYLGRKPTIILNTMQVAKEAFVQNGTIFSGRPSLPLVRWVNKGYGIVMATYGNSWRQQRRFALHTLRDFGLGKKSVEERVAEEAHFLIKEMLKQEGKAFYPIHPIMNSVSNIICSIVFGDRFEYDDRRFAKLLEIINENIR--------FSGSPVAQIFNLVPII-KYFPGPHQKIWHNLQSLRKFMSEEVEKHRKSLDPENL-RDFIDAYLVEMNKQESNEDST--FHEENMLRSTTDLFIAGTETTANTLRWGLIYMMEHPDVQERCHEEIVRVLGFDRFPSMDDRAQLPYTHATVHEIQRYANIVPLGVVHQTTQPTKLRGYHIPAGTNIMSNLTAILTDKDHWKYPDTFNPENFL--DEKG--QFCKNDSFLPFSLGPRVCLGETLARTELFIFFTSLIQQLKFSWPQGAPPP----NMDGVVGLVRSN 487          

Query:  233 PTEKGLPFVGVLHQ-IETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQN-WQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK--QKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 1654
            P  K LPF+G L Q I+ P+   Y R + K+G + ++  G    I+LN  Q  K AFV +G+ +SGR  +  +       GI      N W+ QR F L  L DFG+GK    E V +E   L++E+   +GK    S  I     NII       RF   D +   + D++    +     L Q       IF+ +P +  +        ++  A+ ++  E V+EHRK+LD      D ID +L++   +K  +     F    +LR   +L  AG ETT  TL W  ++M     +Q++ HEEIV ++G +RFP+TNDR  L YT A + EI R +++APL ++H     + + G+++P    +  NL A   D++ W+ P  F PE FL  D  G  ++  N++  AF +G R C GE+LA+ E FIFFTS++Q+    +    S         G  G+VR +     I   RE
Sbjct:   41 PGPKPLPFLGNLPQFIKDPM--TYIRSMPKYGELCSMYLGRNPTIVLNTMQIAKEAFVQNGAVFSGRPSMPLTRWLNKGYGIVMAPYSNSWRQQRRFALHTLRDFGLGKKTVEERVAEEARYLIKEMLKEEGKPFYPSHPIMNAVSNIICSIIFGDRFDYDDKRFAKLLDILNDNVRLVGSPLAQ-------IFNLLPFMKHFPGPHQKVWENDVALKEFIFEVVEEHRKTLD-QENLRDFIDAYLVEM--MKQESNEDSTFHKENMLRSITDLFGAGTETTANTLRWGLIYMMDNPDVQERCHEEIVRVLGFDRFPSTNDRSHLPYTYATVHEIQRNANIAPLGVMHTTTQPTQLQGFHIPAGTDIVPNLTAILNDQEHWKYPDMFNPENFL--DEKG--QFCKNDSFLAFSLGPRVCLGETLARTELFIFFTSLLQQLRFSWPPGASSPNKR----GTAGIVRTTLPFNTICRSRE 498          

Query:  290 FRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPI---FDKMPLLCDWIISRTHRIKHFDAVHKY---FQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDG-LVRC 1618
            +++Y +  KK+G VF + +    V++++ YQ +K + +  G  +SGR      L  +N  G+   +G  W+  R F +  L DFGMG+    E VR+E   L++   T      +  DLI     N+I    +  RF   DD L  +   IT V K      F F   P    ++  P +  +   + H +    AV +     + EV+   K+LD ++  +D I+ FL++  + K +  +   F    LL  S  L  AG+ETT++TL    L+M K+  IQ KV +EI  ++G  R P+  DR+++ YT AV+ EI R   + P ++ H  +ND+  N Y +PK A+V   L +   D K+W+ P  F PE FL  D NG  ++  N+   AFGMGKR C GE++A++E FIFFTS++Q F  + A  + + L    LI   G + RC
Sbjct:   58 YKHYLQFSKKYGPVFTLWFANTPVVVISGYQALKDSMIGMGEEFSGRANYPLLLKVSNGYGVLVSNGDRWKQLRRFCITTLKDFGMGRQSIEEKVREETSYLVQTFSTFGDSAFNPKDLISEAVCNVICSVMLGHRF-ESDDPLLKL--FITAVNKY-----FHFLNSPTGQAYNIFPKIVSFFPGKIHDV--LSAVQETKASLKREVEARWKTLDPSAPPQDFIEAFLLRMEEEKHNPNT--EFNYENLLSTSWNLFSAGMETTSSTLRQGLLYMMKHPDIQAKVQKEIDEVLGPHRSPSIADRQNMPYTDAVVHEIQRSMDLTPTSVPHYMLNDTEFNNYLIPKGAIVLPLLSSVLSDPKLWKNPDCFDPENFL--DENG--RFKKNDGFVAFGMGKRACLGEAMARVELFIFFTSLLQHFTFK-ATVLQEELDTTPLICCFGRMPRC 490          

Query:  233 PTEKGLPFVGVLHQIE-TPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL---MSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK--QKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1540
            P  +GLP VG L Q++   +    ++L + +G +++V  G   V++L   + +K A V     +  R  +     SL   N  G+    G  W+ +R F L +L +FGMG     E + +E   L+  +E  Q K  DA   I+    N+I   T   R+   +     + D+IT   +    D  Q       IF+  P+L  +      RI K+   ++ + Q  ++EH  +  +  E  D +D F+ K+  ++ S      F+D  L+  +  L +AG ETT+ TL+W  L M  Y  +Q++V EEI  ++G  R P   DR  + YT A + EI R +++ P+A  H    D+ + GY++PK   V + +++   ++ +WE P++F P  FL  DI+G+  Y  N+ +    +G R C G++LA+ME F+FFT+++QRF
Sbjct:   42 PGPRGLPLVGNLFQLDLKALPASLDKLSETYGPIYSVSLGQTRVVVLVGNEIIKEALVTQAEMFIDRPEIPVFKKSL--GNYEGLLLSHGWQWRARRRFTLMMLRNFGMGTKSIEEKIAEEAEFLVRAIENKQEKPFDAHSEINKSAANVICSITFGDRYDWNNKTFVKLMDIITENVELSGNDWSQ-------IFNSFPVL-KYFPGPHQRINKNKVVLNAFIQARIEEHDMA-RIQGEPRDYLDAFIDKR--IEDSMNPDTAFSDIALINTTANLFVAGSETTSATLKWGILLMLTYPKVQEQVQEEIDRVVGSNRRPACADRACMPYTNATVHEIQRYANILPMAFPHATTCDTKLRGYFLPKGTQVIALIHSALREKSLWEAPEQFNPGHFL--DIDGNF-YNRNDFMAFSAVGPRICLGKNLARMEVFLFFTALLQRF 468          

Query:  233 PTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFID-GQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLI-THVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVS 1567
            P  K +PF+G +   + P     E + K++G V +V  G   ++ ++ YQ VK   V  G  ++ R     +       GI F   G+ W   R F L  L +FG+GKS   + ++ E   L+E  +  +G   D    ++    NII      KR+   D + ++   L+  ++  Q  LL        + +  P L D+   +    K      ++ ++ + E   + D   +   LID +L    QL+        F++  L+ ++L+L IAG ETT+TTL W  L+M  +  IQ + HEEI  I+G +R P   DR  L Y  AV+ EI R S++ P    H    D     Y +PK  ++  N+ +   DE  W+ P EF PE FL    + D K+   +    F  G R C GE+LAKME F+FF S++Q FE  + + VS
Sbjct:   55 PGPKVIPFLGNVSLFKKPDVALDE-VTKQYGEVCSVMVGKISMVFVSGYQAVKEVLVHQGHEFADRPNTPFNKKVNGGLGIIFAPYGKYWMQHRRFTLSTLRNFGLGKSSIEQTIQAEVGFLIEAFKQ-KGSAFDPHYDLNSAVGNIICSMVKGKRYEYSDKQFQDFLHLVENNLQLQSGLLG------TLCNIFPFLMDFPGPQQIIFKSMAKSKQFIRDIISERHATRD-PIKPMCLIDAYL---SQLEKEDNPNSSFSEQSLIMLALDLFIAGAETTSTTLRWGLLYMMMHPEIQAQCHEEIDKIVGSDRLPCMEDRHSLPYLDAVIHEIQRFSNIVPFGAPHATTADVKFRQYLIPKGTIIMVNMKSVLSDENHWKTPYEFSPENFL----DEDGKFVKPDAFLPFSAGPRVCLGENLAKMELFLFFASLLQHFEFYWPDLVS 485          

Query:  302 ERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFID-GQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK-QKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDA-VHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVS 1567
            + L KK+G V  +  G   V++++ Y+ VK   V+ G  ++ R           N GIA    G  W+ QR F L  L +FG GK+   + +  E   L+E  +  +    D    ++    NII       R+   +++ + +  L+ ++ + Q + L       P   K+P    W      ++ H  + +     + V EHR + D ++   DLID +L +  + K +  S   FT   L+++ +EL I GLETT+ TL W  LFM     IQ + H EI  ++G ER P   DR+ L Y  AV+ EI R  +V PL ++H    D   N Y  PK   V  NL +   D+  W+ P +F P+ FL    + D +   ++    F  G R C GESLAKME F+FFTS++Q FE  +   VS
Sbjct:   64 QELAKKYGEVCTIMLGSTPVVLVSGYEAVKEVLVNRGHEFADRPITPIFTKLTQNIGIALAPYGDPWKQQRRFALSTLRNFGFGKATIADKISIEAKYLIETFKQ-ETSAFDPHLNLNNALGNIICCLLNRNRYDYDNEQFQKLTHLLEYLVQLQAEPLVILCNVFPFLLKLP--GPW-----QKVFHIHSKLQCLLNDIVSEHRATKDQHNP-RDLIDSYLAQIDKEKDNPNS--SFTHQSLIQILIELFIGGLETTSNTLRWGLLFMMMNPDIQARCHGEIDRVVGSERPPCMTDRRSLPYLDAVIHEIQRFGNVLPLGVLHATSKDVQFNDYLFPKGTHVMVNLMSALHDDIHWKTPNKFNPDHFL----DKDGQCIQSDAFLPFSAGPRVCLGESLAKMEIFLFFTSLLQHFEFYWPNSVS 473          

Query:  152 LCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVG--VLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFID-GQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAK-QKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDA-VHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDA 1573
            +C   L      +    T  P G    P  K LP +G       + P     E L KK+G V  +  G   V++++ YQ VK   V+ G  ++ R          +N GIA    G  W+ QR F L  L +FG GK+   + +  E   L+E  +  +    D   +++    NII       R+   +++ + +  L+ H+ + Q + L       P   K+P    W      ++ H    +    ++ V EHR + D ++   DLID +L   H  K        FTD  L+ + +EL I G+ETT+ TL W  LFM     IQ + HEEI  ++G +R P   DR+ L Y  AV+ EI R  ++ P  ++H    D   N Y  PK   V  NL +  +D+  W+ P +F P+ FL    + D +   ++    F  G   C GESLAKME F+FFTS++Q FE  +    S  
Sbjct:   11 ICMVFLTVRAALQVVGSTICPVGFS--PGPKPLPLLGNITAFSCKNPHIGMQE-LAKKYGEVCTIMLGSTPVVLVSGYQAVKEVLVNRGHEFADRPITPLFTKLTHNIGIALAPYGDTWKQQRGFALSTLRNFGFGKATITDKISIEARYLIETFKQ-ETSEFDPKFILNSAVGNIICSLLNGIRYDYNNEQFQKLTHLLEHLVQLQAEPLVILCNVFPFLIKLP--GPW-----QKVFHIHTKLQCLLKDIVSEHRATKDQHNP-RDLIDSYL--AHIDKEKDNPNRSFTDQTLILLLIELFIGGMETTSNTLCWGLLFMMMNPDIQARCHEEIDKVVGSQRPPCMKDRRSLPYLDAVIHEIQRFGNILPFGVLHPTSKDVQFNEYVFPKGTHVMVNLMSAFYDDIHWKTPHKFNPDNFL----DKDGQCIKSDAFLPFPAGPCVCFGESLAKMELFLFFTSLLQHFEFYWPNSASPP 471          

Query:  620 GKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQ-QKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 1654
            G   D    I+    NII       RF   D + RN+  L    A+   +   W   + IF  MP L DW        ++ D V+ +FQE + EHR++ +   +  DLID +L +    K S      FTD  LL +  +L IAG ET++TTL W+ L+M  Y  IQ ++   EI  +IG +R P T DR +L YT AV+ E  R+++VAPL ++H    D    GY +PK   V  NL +   DE  W+ P EF P+ FL  D  G  ++   +   AF  G R C GE+LA+ME F+FFTS++QRF+  +     DA      +  +GL R     K     R+
Sbjct:    1 GDTFDPHFSINNAVSNIICSIVFGNRFDYDDKRFRNLLHLF---AENFRIEGGWRGKICIF--MPWLEDWPGPHQLIFRNADKVNLFFQERIREHRQTREA-GQPRDLIDAYLDEME--KESQDPESTFTDGNLLNVVGDLFIAGTETSSTTLRWALLYMMAYPQIQAERCQREIDEVIGGDRSPNTTDRANLPYTDAVIHEAQRMANVAPLGVLHSTTTDVKFRGYNIPKGTKVLLNLTSVLHDETQWKTPNEFNPDHFL--DNTG--QFVKPDAFLAFSAGPRVCLGENLARMELFLFFTSLLQRFKFHWP----DATSRPNFVAAEGLSRAPVFYKLGVRPRD 330          

Query: 1004 FTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDR--KDLNYTQAVMDEIFRVSSVAPLALVHRAM--NDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEV 1546
            FT+ ++       L A  + +++   W F  ++    +  K+ EE + +   +     N    + + YT  V+ E  R     P+ +V   +  N      Y  PK A++   LY    D +V+E P EF PER+    + G     A +N   FG G   C G++       I F +++ +F +
Sbjct:  321 FTNKEISEAVFTFLFASQDASSSLACWLFQIVADRPDVLAKIREEQLAVRNNDMSTELNLDLIEKMKYTNMVIKETLRYRP--PVLMVPYVVKKNFPVSPNYTAPKGAMLIPTLYPALHDPEVYENPDEFIPERW----VEGSKASEAKKNWLVFGCGPHVCLGQTY----VMITFAALLGKFAL 495          

Query:  797 IFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNII-GKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPL-ALVHRAMNDSSI--NGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERF---------LSTDIN---GDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAE 1558
            +F  +PL  +    R H  K   A+   +   + E RK+ D+  +  DLID  L+K    K         TD ++  + + +L+ G  T+  T  W  L +++   +QQ+++EE + ++ G ++  T +  +++      + E  R+    PL +L  + M D  +    Y +P    V  +    H  ++ +    +F   R+         +  +++   G I    +     FG G+ RC GE  A  +  +  +  ++  +  + E
Sbjct:  242 VFPNLPL--EHYRKRDHAQK---AISGTYMSLIKERRKNNDI--QDRDLIDS-LMKNSTYKDGVK----MTDQEIANLLIGVLMGGQHTSAATSAWILLHLAERPDVQQELYEEQMRVLDGGKKELTYDLLQEMPLLNQTIKETLRMHH--PLHSLFRKVMKDMHVPNTSYVIPAGYHVLVSPGYTHLRDEYFPNAHQFNIHRWNKDSASSYSVGEEVDYGFGAISKGVSSPYLPFGGGRHRCIGEHFAYCQLGVLMSIFIRTLKWHYPE 497          

Query:  308 LIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL-MSSLLAANNSGIAFID-GQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHF----DAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            L K +G VF ++ G   ++++N  +  + A V   ++++GR  L  +SL++ N + IAF D G  W+ QR      L  FG G     E +  E   L++ L  ++G+  +  D ++L  +NII  F    R+   D +   + D      +        F A  + D  P L         +IK      D V    Q++  EH  + + +    DL D  L      +  +  +    D  ++ M+ ++  AGLETT T++ WS +++ +   +Q+++H++I  ++G++R P  +DR++L   +A + E+ R SS+ PL   H    D+ + GY VPKD +V  N++  H D + W  P EF P RFL  D  G     A  +   F  G+R C  ESL KM+ F+F + ++ +F  RF+  V    +  +L G  G   C K  + +  KR
Sbjct:   15 LAKSYGEVFRLKVGSHRIVVVNSIEAAREALVRRANDFAGRPMLYTASLISRNGTDIAFGDFGPLWKQQRKIAHSALRMFGSGLKPLEEKITVEADELIKRLSLVEGRAHNPKDDVNLAVLNIICSFVFGSRYDMDDPEFHTVVDYTEQFVQG-------FRAASLVDYFPWLRHLPNKGLRQIKEACQNRDVV---LQKKYQEHLVTYE-HGVIRDLTDALLSANKASQEESAYLPMTEDHIIMTMN-DIFSAGLETTATSILWSLVYLIRNPKVQEQLHQQIDEVVGRDRAPELSDRENLPLIEATIAEVLRSSSLVPLLFPHSTTTDTHLRGYEVPKDTIVLFNVWNMHHDPQRWSNPDEFDPTRFL--DDKGKFICPATLSYLPFSAGRRVCLAESLGKMQLFLFISRLLHKF--RFS--VPPNGHPPSLEGVFGASLCPKPFRIVVEKR 450          

Query:  233 PTEKGLPFVGVLHQIETPIFRYYERLIKKHG-SVFAVRY-GMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQ---NWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNI---NDLITHVAKQKDLLQF--W--FFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGE--DLIDRFLIKQHQLKAS-TGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSD 1570
            P     PFVG   QI   + +    L K++G  VF V+  G R VII N     +     +G + + R      + A + +G + I G+    W+ QR  +   L  +G G  +   ++ QE  NL +     QG  VD    + L  +N+I      KR+   D +  +I    + +  +A  ++ L +  W  FF L +  KM              +   A  +  Q ++ EHR++     EGE  DL D  L      K     ++   T+  LL    ++ +AG ETTTT L W FL+++ Y  +Q ++H+E+ ++I   R P   DRK L Y +A + E+ R+S V PL +  +A    +I GY +P++  V+ NL+A H DE  W  P +F P RFL    N    Y+    +  FG G R C GESLAKME F+F + ++ RF++       D
Sbjct:   30 PGPPLYPFVGNFPQIGPVLHKSLTSLGKQYGRGVFQVQLLGKRFVIIDNIKLARQVLLKKNGRDVADRTS-AYVIDAISRNGCSVIFGKYSPTWKLQRRVVHSALRMYGSGVRILEALILQEVDNLCDIFANSQGAPVDTKLPLTLSVMNVICALVFGKRYGLDDAEFTDIVATTESMAKLASPENPLIYMPWLRFFPLQVVKKMK-------------ETVTARDRLIQRKITEHRETY---KEGEIRDLTDALLKSLEDAKQEDNNAMSLLTEDHLLIAINDVFMAGFETTTTALRWIFLYVAAYPEVQARIHQELDDVISFGRDPLIADRKSLPYLEATILEVLRISPVFPL-IRRKARKQLNIGGYCIPEETFVYVNLWAIHHDEAEWVDPYKFRPSRFLE-GTNSASAYS----MLPFGAGVRVCVGESLAKMELFLFVSRLLHRFKLNLKGQCPD 467          

Query:  233 PTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR-WRLMSSLLAANNSGIAFIDGQNW-----QTQRTFM--LKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHF-----DAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEG---FTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEE 1585
            P    LP +G LH + +       RL   +G ++ +  G +  ++LN Y+  K A +  G+ ++GR    + S  +    G+ F   QN+     + Q+T M  +K       G+++  EI+  E   L +   +   +  D    +     N++ + T  +RF+  +++   + D +    +      F        D  PLL  +  S   R++       D ++K F+E  D  R    + ++ +DL    + + +Q  + T S       TD  ++    + ++AG ET T  L W+  F  KY  +Q +  ++I  +I  ++  T  DRK L Y +A + E+ R+ S+ PLA+ H AM D  + GY++ K   V  NL+A   D KVW+ P EF PERFL  D  G     ++E    +GMG R C GE LA+ME F+F   +++ FE R +E + + L  E
Sbjct:    1 PGPLPLPLIGNLHLLSSKPHLDLARLGNIYGPIYTLNMGSQLAVVLNSYEIAKEALMKRGNAFAGRPHHFVGSKFSRGGKGVGF---QNYTPTLRRQQKTIMKTVKYFETLKTGENLQ-EIITNEVDYLCDLFVSHGCQDFDPRRDMTFAAGNVVGRITFGERFTVENEEFWQLMDSLKIFVEGLTATSF-------IDAFPLLRYFPFSLVKRVQTAVKLRDDVLNKRFREHQDRLRGDGMVLAKSKDLTYALIEEANQKTSRTDSQSDTLILTDDHVMMTMNDTIMAGSETPTMLLLWNIYFFVKYPDVQARAFKQIDKVISPDQPITWEDRKRLPYLEAFIAEVMRIISIMPLAVPHLAMVDMVLAGYHISKGTTVIVNLWAMGHDPKVWDAPMEFRPERFL--DSRGGFSTASSEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRASEALPEMLDGE 454          

Query:  257 VGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR-WRLMSSLLAANNSGIAFIDGQNW-----QTQRTFM--LKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLK--ASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEE 1585
            +G LH + +       RL   +G ++ +  G +  ++LN Y   K A +  G+ ++GR    + S  + +  G+ F   QN+     + Q+T M  +K       G+S+  EI+ +E   L + L     +  D    +     N++ + T  +R+  G+ +   + + +T   +      F   A P    +P      + +  +++  D ++  F++ +   + S    +   DL    + + ++    A++ S     D  ++ M+ ++++AG ET T TL W   F+ KY  +Q +  E++ ++    +      RK L Y +A + E+ R++ V PLA+ H AM D+++ GY++PK   V  NL+A   D KVW+ P EF PERFL  D  G     + E    +GMG R C GE LA+ME F+F   +++ FE R +E + + L  E
Sbjct:   39 IGNLHLLSSKPHLDLTRLGDIYGPIYTLNMGSQLAVVLNSYDIAKEALMKRGNAFAGRPHHFVGSKFSRDGKGVGF---QNYTPTLRRQQKTIMKTVKFFDTLKTGESLQ-EIITKEVDYLCKRLLIFGDQSFDPRHEVTFAAGNVVGRITFGERYKGGNKEFWQLMESLTIFVEGLTATSF-IDAFPFLKYVPFSMVKRVEKAVKLRD-DVLNDKFRDHLKNLQNSTISTTTNRDLTYALIDEANKTNCFANSQSDALTIDHVIMTMN-DMIMAGSETPTMTLLWILYFLVKYPDVQVRAQEQVDDVSRNVQPLAWEGRKRLPYLEAFIAEVLRITGVMPLAIQHLAMADTALAGYHIPKGTTVIVNLWAMGHDPKVWDAPMEFRPERFL--DSRGGFSTASTEGFTPYGMGLRSCPGEQLARMELFLFTVRLLRMFEFRASEALPEMLDAE 482          

Query:  233 PTEKGLPFVGVLHQIETPIFRY-YERLIKKHGSVFAVR-YGMRDVIILNDYQTVKSAFVDDGSNYSGRW-RLMSSLLAANNSGIAFID---GQNWQTQRTFMLKVLHDF--GMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVH-KYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEG-FTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRF 1540
            P    LP +G L  I++    +    L K HG +  +  +GM+ V++ +     +       ++++GR  R     ++     IA  D   G  W+  R  +   L  +   +G +++ E+ + E     ++L +  G  VD+ D   L  +NII  F   K F + D +     +L+T   K  D L     +  I D  P L  + +  +   K    +  K     +  H+++ + N    DL D FL  +  ++       G  TD ++  M +++ +AGLETT T+L W   ++     +Q +V   I ++IG  R P  +DR+ L Y +A++ E+ R+S   PL L H+++ D++I+GY +PK   V  NL+A H D + W +P +F P+RF++ D  G  +   + N   F  G+R C GESLAKME F+  T ++Q+F
Sbjct:    3 PGPTPLPLIGNLLSIKSSNIHFELANLAKTHGDIMMIELFGMKIVVVTSGPLAREVLMGKHINDFAGRPKRFTFEYMSKGYKDIALNDYSPGLVWK--RKIVHSGLRKYFPSLGDTIAKELAKLE-----DKLNSDVGVPVDSKDEFFLLVLNIICSFLSGKAFDKEDPEFSETLELVT---KTVDTLSM---SASILDAFPFLIHFPLQASKNFKRIAELRDKLMGNILTFHKETFNEN-HIRDLTDAFLKAKLDIEREDKKAAGEVTDEEVALMMMDVYLAGLETTVTSLRWIIAYLMNNQEVQSRVQSRIDDVIGDRR-PLMSDRQGLPYMEALVAEVLRLSPPIPLGLPHKSILDTTIDGYTIPKGTTVLFNLWAIHHDPREWPEPDKFDPDRFINED--GKFEVPGDRNFLPFMAGRRVCLGESLAKMELFLIMTRLLQQF 431          

Query:  299 YERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKH-FDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDAL 1576
            + +L  ++G ++++R+G R  ++LN ++ +K A V  G +   R  L      A   G+ F +G NW  QR F L  L  FG GK     ++  E  +  EEL+  +G+ +D   +I+    NII       RF+ GD K + +  L     + +     W     +++   L+   +      ++H +  V  +  EE+ EH+KS D  S+  D ID +L +  + K   GS   F +  L+   L+L +AG ETT+TTL W+FL+M+KY  IQ+KV  EI  +IGK R P   DR +L YT AV+ E+ R+ ++ PL+L H    D  + G+ +PK  L+  NL +  FDEK WE P  F P  FL    N D K+        F  GKR C GE+LA+ME F+FFTS MQ F       V   L
Sbjct:   89 FSKLAAEYGDLYSLRFGQRWTVVLNGHKALKEALVTKGDSVVDRPHLPLQDEIAKGLGVIFSNGANWTEQRRFALSTLRYFGFGKKSLEPVILNEFAHCAEELKRFKGEPLDPHLIINNTVSNIICHLVFGHRFNYGDKKFKKLMLLFDRALQIEA--SIW---AQLYNSFTLIMRCLPGPHKTLQHIWREVQDFIGEELKEHKKSWD-PSDARDYIDFYLTEIQKTKGQEGST--FDEENLIMCVLDLFVAGSETTSTTLRWAFLYMAKYPEIQEKVQAEIHKVIGKSRPPCMEDRAELPYTDAVIHEVQRIGNIVPLSLPHATNKDVQLGGFTIPKGVLIIPNLTSVLFDEKEWETPHAFNPGHFL----NKDGKFVKRGAFIPFSAGKRLCLGENLARMELFLFFTSFMQHFSFSMPAGVEPVL 503          

Query:  233 PTEKGLPFVGVLHQIETPIFRY-YERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWR--LMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            P  + LPF+G LH+I   I    ++    K+G+VF++       ++LN  + +K A +  G ++  R +  L S L+   N GI   +G  W+ QR F L  L +FG+GK    + +++EC  + +     QGK  DA  L++    NII      +RF   D + + I   +T V K    LQ  F AL  ++  P L         ++    D +  + + +++EH+++LD     +D ID FLI   +++ + G   GF    L   +L+L  AG ETTTTTL W  LFM  Y  IQ++VH EI  +IG  R P+  D++++ YT AV+ EI R+  + P+ +   A  D+ ++ Y +PK  ++   L+    DE VWE P  F P+ FL    N D  +   E    FG GKR C GE LA+ME F+FFTS +QRF    A        +  L G  G +R  K  +     R
Sbjct:   42 PGPRSLPFIGDLHRIRPTILHLQFKEFAAKYGNVFSLNIFGGKTVVLNGTKLLKEALIQKGDDFVDRPQIPLFSDLI--ENKGIVMTNGIQWKHQRRFALHTLRNFGLGKKTMEKYIQEECHYITQAFAEHQGKPFDAQPLLNSAVSNIICCLVFGERFEYSDKEYQQILQDLTEVVK----LQGSFSAL-AYNVFPWLMKRFPGPLQKLFTLVDKIMDFVKIKIEEHKENLDPACP-KDYIDSFLI---EMEKNQGEDFGFDIKNLCACTLDLFGAGSETTTTTLYWGLLFMIHYPDIQEEVHAEIDAVIGSSRQPSMADKENMPYTDAVIHEIQRMGDIVPIGVARMASRDTMLDNYTIPKGTMIMPALHTVLHDESVWETPHSFNPQHFL----NQDGTFKKREAFFPFGAGKRVCLGEQLARMELFLFFTSFLQRFSFSTA-----GGEKPPLEGRMGTIRSPKSYRLCAVPR 498          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR--WRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIG 1597
            P   GLPFVG    I+      Y+ ++ + +G+VF+VR G +  + ++ Y+ VK A V    N+  R    +       N++G+ F +G+ W+ QR F L  L  FG+GK+   + + +E  +L +++E  +G     + L +    NII +  M KRF   D+  + +   I+   + +     W     +++  P L   +    ++I +++  V  +  +E+  H++ LD N+   D ID F+I   +++    S  GF D  L   SL+L +AG ETT+TTL W+ +++ K+  +Q KV +EI  +IG+ R P+  DR +L YT AV+ EI R+ ++ PL  +  A  D+++ GY++PK   +   L +  FD+  WE P  F PE FL    + D K+   E    F  GKR C GE LA+ME F+F   ++Q+F     E V   L  E + G
Sbjct:   39 PGPLGLPFVGNFLTIDGKHPHIYFSKMAESYGNVFSVRLGSQATVFVSGYKMVKEALVTQAENFVDRPFSEIGGRFYEGNSNGLFFSNGEKWKKQRRFALSTLRTFGLGKNTMEQSICEEIRHLQQQIENEKGGPFSPAGLFNNAVSNIICQLVMGKRFDYDDNNFQVMMKYISEAVQLEG--SIWGI---LYESFPGLMKHLPGSHNKIFRNYKIVQDFLAQEIKIHKQDLDPNNP-RDYIDSFII---EMEKHQNSDLGFNDANLAFCSLDLFVAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVVHEIQRIGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFL----DADGKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGVE--LSTEGITG 482          

Query:  233 PTEKGLPFVGVLHQIETP-IFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDK----LRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKR 1651
            P    LPF+G LH+I+   +   +    +K+G+VF++       +ILN Y+ VK A V  G ++  R  +   +   +N GI   +G +W+ QR F L  L +FG+GK      ++ EC  + +     QGK  DA  LI+    NII      +RF   D +    LRN+NDL+        +L   F  L    ++P     I S T +I  F  +      +++EH+ + D  S  ED ID FLI   +++ S     GF    +   +++L +AG ETTTTTL W  L+M  Y  IQ+KVH EI  +IG  R P+  D++ + YT AV+ EI R+  + P  +  +A  D++++ Y +PK  ++   L++   DE +W+ P  F P+ FL    + D K+   E  N FG GKR C GE LA+ME F+FFTS+ QRF   F+    + L  E+ +   G  RC K  + I   R
Sbjct:   42 PGPHSLPFIGDLHRIQPARLHVQFTEFAEKYGNVFSLHLLGERTVILNGYKQVKEALVQQGDDFVDRPTIPLFVDTIDNKGIVMSNGNSWKQQRRFALHTLRNFGLGKKTMETYIQNECHYITQTFADKQGKPFDAQFLINNAVSNIICCLVFGERFEYSDQEYQKILRNLNDLLILEGSVSAMLYNMFPWL--MKRLPGPHQKIFSLTRKIIDFVKI------KINEHKGNFD-PSAPEDYIDSFLI---EMEKSQDKDSGFDIDNMCICTMDLFLAGTETTTTTLYWGLLYMIYYPDIQEKVHAEIDAVIGSSRQPSMADKESMPYTDAVIHEIQRMGDIVPQGVFRQANRDTTLDKYTIPKGTIIVPALHSVLHDESMWDNPHSFDPKNFL----DKDGKFCKREAFNPFGAGKRVCLGEQLARMELFLFFTSLFQRFS--FSAPTGEQLSLESRM---GATRCPKPFRVIAAPR 498          

Query:  296 YYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGR--WRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRI-KHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIG 1597
            Y+ +L + +G+VF+VR+G    + ++ Y+ VK A V    N+  R    + +       +GI   +G+ W+ QR F L  L  FG+GK+   + + +E  +L  E+E+ +G+    + L +    NI+ +  M KRF   D     +   ++ V + +     W     +++  P L   +    + + K FD +  +  +E+  H+K LD N+   D ID FLI   +++    S  GF +  L   SL+L +AG ETT+TTL W+ +++ K+  +Q KV +EI  +IG+ R P+  DR +L YT AV+ EI R  ++ PL  +  A  D+++ GY++PK   +   L +  FD+  WE P  F PE FL    + D K+   E    F  GKR C GE LA+ME F+F   ++Q+F     E V   L  E + G
Sbjct:   61 YFTKLAETYGNVFSVRFGSETSVFVSGYKMVKEALVTQAENFVDRPYSPMATRFYQGPTNGIFMSNGEKWKKQRRFALSTLRTFGLGKNTMEQCICEEIRHLQAEIESEKGQLFTPTGLFNNAVSNIVCQLVMGKRFDYNDHDFHTMIKYLSEVLRLEG--SVWGL---LYEAFPGLMKHLPGPHNEMFKDFDILRDFLDQEIKMHKKDLDRNNP-RDYIDSFLI---EMEKHQNSDLGFNEANLAFCSLDLFLAGTETTSTTLMWALIYLIKHPDVQVKVQQEIDRVIGQNRLPSMADRPNLPYTDAVIHEIQRFGNIVPLNGLRVAAKDTTLGGYFIPKGTALMPMLTSVLFDKTEWETPDTFNPEHFL----DADGKFVKKEAFLPFSAGKRVCLGEGLARMELFLFLVGLLQKFSFSVPEGVE--LSTEGITG 482          

Query:  167 LGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 1654
            LG  I+WK  +RT I KGL+ IPTEKGLPFVGVLHQ+ETPI +YYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRL+SSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRF+EDVSDALYEEALIGNDGLVRCSKINKFIFTKRE
Sbjct:   11 LGVTIYWKLIKRTSISKGLKIIPTEKGLPFVGVLHQMETPILKYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLVSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 506          

Query:  149 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTK 1648
            YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRW++  SLL +  + IAFIDG+ WQ QR F+LKV HDFG+GKSVSYEI RQEC  L++ELETL GK VD SDLIHLYTVNIISKF  NKRFSR +DK + I +L     KQKD LQ  F+ LP+FDKM  LCDWI+ RT+R   FDAV K  QEE+DEHRK+LDLNSEGEDLIDRFLIKQHQLKASTGS + FTDFQL R+SLELL+AGLETTTT+LEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPT ND+KDL+YTQAV+DEIFRVSSV PLALVHRAMNDSSINGY+VPKD+LV+SNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKY AN++LN FG+GKRRC GESLA+ME F+FFTSIMQRFEVRFAEDVSDALYEEALIGN+G+VR SKI  +IFTK
Sbjct:    5 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWKVSQSLLMSGYARIAFIDGEMWQIQRPFVLKVFHDFGIGKSVSYEIARQECLYLIDELETLNGKWVDVSDLIHLYTVNIISKFITNKRFSRKEDKYKTIGNLGQQALKQKDCLQLLFYTLPLFDKMTWLCDWILRRTNRKVLFDAVDKLVQEEIDEHRKTLDLNSEGEDLIDRFLIKQHQLKASTGSSKQFTDFQLRRLSLELLLAGLETTTTSLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTLNDKKDLHYTQAVIDEIFRVSSVGPLALVHRAMNDSSINGYHVPKDSLVYSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYKANDSLNPFGVGKRRCTGESLARMEIFVFFTSIMQRFEVRFAEDVSDALYEEALIGNEGIVRGSKIKNYIFTK 504          

Query:  149 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 1654
            YLCTFLLGAAI+WKF R T IPK L+RIPTEKGLP +GVLH+IE+PI RYYERLIKKHGSVFAVR+GMRDVIILNDYQTVKSAFV DGSNYSGRW++  SL+ + N+GIAFIDG+ WQTQRTFMLKV HDFGMGKSVSYEIVRQEC  L++ELETL GK VD SDLI LYTVNIISKF MNKRFSR +DK + ++DL  H  KQKD  QF F+ LP+FDKM  LCDWI+ RT+R   FDAV K  QEE+DEHRK+LDLNSEGED IDRFLIKQHQLK STGS E FTDFQLLR+S+ELL+AGLETT TTL WSFLFMSKYT IQ+KVH EI+  +GKERFPT NDRK L+YTQAVMDE+ RVSSVAPLA VHRAM DSS+NGYYVPKD+LVFSNLYAC+FDEKVW+KPKEFYPE FLSTDING I YT NE+LN FG+GKRRC GESLA+ME F+FFTSIMQRFEV+FAEDVS+ALYEEALIGN+G+VR SKI  FIF K E
Sbjct:    5 YLCTFLLGAAIYWKFIRLTSIPKELKRIPTEKGLPIIGVLHKIESPILRYYERLIKKHGSVFAVRFGMRDVIILNDYQTVKSAFVHDGSNYSGRWKVSQSLMMSGNAGIAFIDGEMWQTQRTFMLKVFHDFGMGKSVSYEIVRQECHFLIDELETLIGKCVDVSDLIQLYTVNIISKFIMNKRFSRKEDKYKRLSDLSQHALKQKDFFQFLFYTLPLFDKMNWLCDWILRRTNRRIPFDAVDKLVQEELDEHRKTLDLNSEGEDFIDRFLIKQHQLKTSTGSSEQFTDFQLLRLSMELLVAGLETTMTTLGWSFLFMSKYTNIQKKVHNEIIKTVGKERFPTLNDRKYLHYTQAVMDEVIRVSSVAPLAFVHRAMEDSSLNGYYVPKDSLVFSNLYACNFDEKVWKKPKEFYPEHFLSTDINGVIIYTPNESLNPFGVGKRRCVGESLARMEIFVFFTSIMQRFEVKFAEDVSEALYEEALIGNEGVVRSSKIKNFIFEKLE 506          

Query:  149 YLCTFLLGAAIFWKFTRRTPIPKGLRRIPTEKGLPFVGVLHQIETPIFRYYERLIKKHGSVFAVRYGMRDVIILNDYQTVKSAFVDDGSNYSGRWRLMSSLLAANNSGIAFIDGQNWQTQRTFMLKVLHDFGMGKSVSYEIVRQECFNLLEELETLQGKRVDASDLIHLYTVNIISKFTMNKRFSRGDDKLRNINDLITHVAKQKDLLQFWFFALPIFDKMPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTK 1648
            +L   +   A+ + F R  PIPKGL+++P EKG P +G+L  +  PI  YYERLIKKHG VF ++ G+R + +LNDY+ +++A +D+  N+SGRWRL  SLL   N+GI   DG      R F++KV+H+FGMG   S   ++ EC  LLE LE  QG+R+  SD+I  Y  NII+KF MNK FS GD KL  I +++T +A+ KD+ QF +F LPI D+ P +CD+++S T R   F+ VH+  Q+E++EHRK+ D+ +EGEDLIDRFL+KQ QLK+S  S++ FTDFQL+R  LEL +AG ETT+T   WS  FMSKY  IQ KVH+EI++ IG ER PT NDRKDL YT AVMDEI R+SSV PLAL+HR  ND+ +N Y++PKD+LV  NLYACH D  VWEKP+EFYPE FLS   NG+IKY   + LN FGMGKR+C GESL +M+ FIFF SI+QRF+V FA+ V+++ ++EAL  N+G+VR   IN+F+F +
Sbjct:    5 FLLILISVVALLFNFLRPRPIPKGLQKVPIEKGFPLIGILPLLTFPILEYYERLIKKHGPVFGMKMGLRTIFVLNDYRAIRNALIDNKDNFSGRWRLFQSLLGTQNAGIVSTDGDQTHIHRRFIIKVMHEFGMGTLRSLTNIQTECTALLECLEKCQGERIQVSDIIPTYMANIITKFLMNKTFSVGDPKLNLIKNILTEIARTKDIFQFLYFTLPILDRFPRVCDFLMSFTTRKDLFNKVHRILQQEIEEHRKTFDVKNEGEDLIDRFLMKQDQLKSSEESVKSFTDFQLVRHLLELFLAGYETTSTIFHWSLFFMSKYQEIQSKVHQEIIDSIGTERLPTNNDRKDLTYTTAVMDEILRLSSVLPLALIHRTTNDTEVNSYFIPKDSLVLINLYACHVDPNVWEKPREFYPEHFLSPKENGNIKYVPKDQLNPFGMGKRQCIGESLGRMQYFIFFVSILQRFQVSFADPVTESQFQEALRANEGIVRYPSINEFVFNR 504          

Query:  809 MPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFAEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 1654
            MPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRF+EDVSDALYEEALIGNDGLVRCSKINKFIFTKRE
Sbjct:    1 MPLLCDWIISRTHRIKHFDAVHKYFQEEVDEHRKSLDLNSEGEDLIDRFLIKQHQLKASTGSIEGFTDFQLLRMSLELLIAGLETTTTTLEWSFLFMSKYTIIQQKVHEEIVNIIGKERFPTTNDRKDLNYTQAVMDEIFRVSSVAPLALVHRAMNDSSINGYYVPKDALVFSNLYACHFDEKVWEKPKEFYPERFLSTDINGDIKYTANENLNAFGMGKRRCAGESLAKMEAFIFFTSIMQRFEVRFSEDVSDALYEEALIGNDGLVRCSKINKFIFTKRE 282