SMED30035396

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R IFC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R IFC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  136 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH-NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYK-KSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV--NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGAN 1461
            +  +  ++ +NV G RF+ +  T++  P       EK    N+   EYFFDRDPEVF+CVLN  R G++H P   C   ++ E+  +GI +   +  CC     +     +   N E+      SE+ + S+  +S FRQ +W+  E P +S+LAL++  V    +   +   VV TV   +VP + +    +R      Y  A F   +    V I T + + R     +    I S  +IIDV++++P+Y  L+ +  E  +  F             L +  V R F+  R  +G ++L YT+K  A++L  ++  + +A+++F++V+FY E     S F +IP SFW+ IVT+TT GYGDMVPKT  G +   ICSL GVL+IA  VP++V+NF   Y               +       +RA  K +  R +  KT  +N
Sbjct:   35 NKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGI-LPEIIGDCCYEEYKD-----RKRENAERLMDDNDSENNQESMPSLS-FRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGER------YSVAFFC--LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFV-----------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---------------HQNQRADKRRAQKKARLARIRVAKTGSSN 439          

Query:  136 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH-NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYK-KSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV--NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGAN 1461
            +  +  ++ +NV G RF+ +  T++  P       EK    N+   EYFFDRDPEVF+CVLN  R G++H P   C   ++ E+  +GI +   +  CC     +     +   N E+      SE+ + S+  +S FRQ +W+  E P +S+LAL++  V    +   +   VV TV   +VP + +    +R      Y  A F   +    V I T + + R     +    I S  +IIDV++++P+Y  L+ +  E  +  F             L +  V R F+  R  +G ++L YT+K  A++L  ++  + +A+++F++V+FY E     S F +IP SFW+ IVT+TT GYGDMVPKT  G +   ICSL GVL+IA  VP++V+NF   Y               +       +RA  K +  R +  KT  +N
Sbjct:   35 NKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGI-LPEIIGDCCYEEYKD-----RKRENAERLMDDNDSENNQESMPSLS-FRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGER------YSVAFFC--LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFV-----------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---------------HQNQRADKRRAQKKARLARIRVAKTGSSN 439          

Query:  136 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH-NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYK-KSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV--NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGAN 1461
            +  +  ++ +NV G RF+ +  T++  P       EK    N+   EYFFDRDPEVF+CVLN  R G++H P   C   ++ E+  +GI +   +  CC     +     +   N E+      SE+ + S+  +S FRQ +W+  E P +S+LAL++  V    +   +   VV TV   +VP + +    +R      Y  A F   +    V I T + + R     +    I S  +IIDV++++P+Y  L+ +  E  +  F             L +  V R F+  R  +G ++L YT+K  A++L  ++  + +A+++F++V+FY E     S F +IP SFW+ IVT+TT GYGDMVPKT  G +   ICSL GVL+IA  VP++V+NF   Y               +       +RA  K +  R +  KT  +N
Sbjct:   35 NKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGI-LPEIIGDCCYEEYKD-----RKRENAERLMDDNDSENNQESMPSLS-FRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGER------YSVAFFC--LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFV-----------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---------------HQNQRADKRRAQKKARLARIRVAKTGSSN 439          

Query:   64 PFSMKFLNRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLT------NSMMRIKNL---------RNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEI---------------------KRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEV--PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGH-IKRALGKVKQIR-KKSKKTKGANHRHCNSSSENVTVFTIMEESESVK 1521
            P  + F        P RR    +    V +NV G+R + + + +K+IP    + L   L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      +++  I++L             K F  + +    ++      +  +W + ++P SS  A + S++    ++     F++ T  S  F I  +++                      + VTS P+    ++ +I  I  +I   +L+ R++FC +    + S  TIIDV+S   F++  +   I  QT        G+   +  L +  VLR F++ + + G ++L+ T K SA +L L++ FV++A+++F+++++Y E      D+ F +IP   WW +VTI+T G+GDMVPKT LG LV  +C+L GVL IA  VP++V+NF   Y+H+   ++  +       L+ H +K AL  VKQ   K  KK+  A      ++ +N      M ++ + K
Sbjct:    3 PALLAFFKPAEMASPQRRESWMDTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLD-ANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPS--FQIPDIDVFYSLRVVDEGGFKNYHKTIGTDKPVTS-PHPNFFYVDLICNIWFTI---ELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQT--------GSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAK--LPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASK 513          

Query:   64 VKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLT------NSMMRIKNL---------RNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEI---------------------KRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEV--PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGH-IKRALGKVKQIR-KKSKKTKGANHRHCNSSSENVTVFTIMEESESVK 1440
            V +NV G+R + + + +K+IP    + L   L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      +++  I++L             K F  + +    ++      +  +W + ++P SS  A + S++    ++     F++ T  S  F I  +++                      + VTS P+    ++ +I  I  +I   +L+ R++FC +    + S  TIIDV+S   F++  +   I  QT        G+   +  L +  VLR F++ + + G ++L+ T K SA +L L++ FV++A+++F+++++Y E      D+ F +IP   WW +VTI+T G+GDMVPKT LG LV  +C+L GVL IA  VP++V+NF   Y+H+   ++  +       L+ H +K AL  VKQ   K  KK+  A      ++ +N      M ++ + K
Sbjct:    7 VILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLD-ANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPS--FQIPDIDVFYSLRVVDEGGFKNYHKTIGTDKPVTS-PHPNFFYVDLICNIWFTI---ELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQT--------GSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAK--LPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASK 490          

Query:   64 VKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLT------NSMMRIKNL---------RNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEI---------------------KRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEV--PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGH-IKRALGKVKQIR-KKSKKTKGANHRHCNSSSENVTVFTIMEESESVK 1440
            V +NV G+R + + + +K+IP    + L   L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      +++  I++L             K F  + +    ++      +  +W + ++P SS  A + S++    ++     F++ T  S  F I  +++                      + VTS P+    ++ +I  I  +I   +L+ R++FC +    + S  TIIDV+S   F++  +   I  QT        G+   +  L +  VLR F++ + + G ++L+ T K SA +L L++ FV++A+++F+++++Y E      D+ F +IP   WW +VTI+T G+GDMVPKT LG LV  +C+L GVL IA  VP++V+NF   Y+H+   ++  +       L+ H +K AL  VKQ   K  KK+  A      ++ +N      M ++ + K
Sbjct:    7 VILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLD-ANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPS--FQIPDIDVFYSLRVVDEGGFKNYHKTIGTDKPVTS-PHPNFFYVDLICNIWFTI---ELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQT--------GSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAK--LPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASK 490          

Query:   64 YRRTGD-SEESSV--------VKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLT------NSMMRIKNL---------RNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEI---------------------KRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEV--PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGH-IKRALGKVKQIR-KKSKKTKGANHRHCNSSSENVTVFTIMEESESVK 1476
            YRR  + S E+S+        V +NV G+R + + + +K+IP    + L   L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      +++  I++L             K F  + +    ++      +  +W + ++P SS  A + S++    ++     F++ T  S  F I  +++                      + VTS P+    ++ +I  I  +I   +L+ R++FC +    + S  TIIDV+S   F++  +   I  QT        G+   +  L +  VLR F++ + + G ++L+ T K SA +L L++ FV++A+++F+++++Y E      D+ F +IP   WW +VTI+T G+GDMVPKT LG LV  +C+L GVL IA  VP++V+NF   Y+H+   ++  +       L+ H +K AL  VKQ   K  KK+  A      ++ +N      M ++ + K
Sbjct:    6 YRRARENSNETSLSWMDTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLD-ANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPS--FQIPDIDVFYSLRVVDEGGFKNYHKTIGTDKPVTS-PHPNFFYVDLICNIWFTI---ELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQT--------GSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAK--LPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASK 510          

Query:   64 RRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLT------NSMMRIKNL---------RNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEI---------------------KRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEV--PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGH-IKRALGKVKQIR-KKSKKTKGANHRHCNSSSENVTVFTIMEESESVK 1473
            R+T   +    V +NV G+R + + + +K+IP    + L   L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      +++  I++L             K F  + +    ++      +  +W + ++P SS  A + S++    ++     F++ T  S  F I  +++                      + VTS P+    ++ +I  I  +I   +L+ R++FC +    + S  TIIDV+S   F++  +   I  QT        G+   +  L +  VLR F++ + + G ++L+ T K SA +L L++ FV++A+++F+++++Y E      D+ F +IP   WW +VTI+T G+GDMVPKT LG LV  +C+L GVL IA  VP++V+NF   Y+H+   ++  +       L+ H +K AL  VKQ   K  KK+  A      ++ +N      M ++ + K
Sbjct:   46 RKTSWMDTEHRVILNVGGIRHETYSHVLKKIPATRLSRLTPNLANYDPVLNEYFFDRHPGVFSMILNYYRTGKLHYPTNVCGPLFEEELEFWGLD-ANQVEPCCWMTYTQHRDTQDTLAVIESLDLDGDPPTQEEIAKKFGWEDDYYTGNMSQWQRLKPRVWALFDEPWSSKYARVISSLSVAFILASTCSFILKTDPS--FQIPDIDVFYSLRVVDEGGFKNYHKTIGTDKPVTS-PHPNFFYVDLICNIWFTI---ELLIRSLFCPSFHKFVRSPLTIIDVISTGAFFFESLLHAILIQT--------GSLVTLDFLSMICVLRLFKLTQHFSGLKILIQTFKASAQELFLLVFFVILAIVIFAALVYYAERSQLNKDNQFTSIPLGLWWSLVTISTVGFGDMVPKTYLGMLVGSLCALMGVLTIALPVPVIVSNFSNLYSHSQARAK--LPKKRRRVLQAHEVKPALLGVKQHHGKHRKKSSSATFNQPPANFKNANGGPSMHDNSASK 540          

Query:  262 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFY---KKSESE------------RNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTS----------LPYVKADFIQIIYYITV---SILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLI----ASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSH--FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTH 1461
            DSE   V  +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  VLN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      + L   ++      K SE E            + +I      +  IW + ++P SS+ A     V    +   +  F + T   +     ++ I RN+T           L   + +     +YI     +  TF+++ R I   N    I S   IID ++ + FY +L+    AS++E              D+++   I  ++R F++ R   G ++L+ T + SA +L L++ F+++ +++F+S+++Y E   P+ H  F +IP   WW +VT+TT GYGDM PKT +G  V  +C+L GVL IA  VP++V+NF +YY+H
Sbjct:    7 DSENRVV--LNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDM-----RVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENA------------DILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSH 422          

Query:  262 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFY---KKSESE------------RNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTS----------LPYVKADFIQIIYYITV---SILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLI----ASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSH--FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTH 1461
            DSE   V  +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  VLN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      + L   ++      K SE E            + +I      +  IW + ++P SS+ A     V    +   +  F + T   +     ++ I RN+T           L   + +     +YI     +  TF+++ R I   N    I S   IID ++ + FY +L+    AS++E              D+++   I  ++R F++ R   G ++L+ T + SA +L L++ F+++ +++F+S+++Y E   P+ H  F +IP   WW +VT+TT GYGDM PKT +G  V  +C+L GVL IA  VP++V+NF +YY+H
Sbjct:    7 DSENRVV--LNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDM-----RVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENA------------DILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSH 422          

Query:  262 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFY---KKSESE------------RNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTS----------LPYVKADFIQIIYYITV---SILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLI----ASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSH--FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTH 1461
            DSE   V  +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  VLN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      + L   ++      K SE E            + +I      +  IW + ++P SS+ A     V    +   +  F + T   +     ++ I RN+T           L   + +     +YI     +  TF+++ R I   N    I S   IID ++ + FY +L+    AS++E              D+++   I  ++R F++ R   G ++L+ T + SA +L L++ F+++ +++F+S+++Y E   P+ H  F +IP   WW +VT+TT GYGDM PKT +G  V  +C+L GVL IA  VP++V+NF +YY+H
Sbjct:    7 DSENRVV--LNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDM-----RVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENA------------DILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSH 422          

Query:  262 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFY---KKSESE------------RNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTS----------LPYVKADFIQIIYYITV---SILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLI----ASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSH--FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTH 1461
            DSE   V  +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  VLN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      + L   ++      K SE E            + +I      +  IW + ++P SS+ A     V    +   +  F + T   +     ++ I RN+T           L   + +     +YI     +  TF+++ R I   N    I S   IID ++ + FY +L+    AS++E              D+++   I  ++R F++ R   G ++L+ T + SA +L L++ F+++ +++F+S+++Y E   P+ H  F +IP   WW +VT+TT GYGDM PKT +G  V  +C+L GVL IA  VP++V+NF +YY+H
Sbjct:    7 DSENRVV--LNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDM-----RVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENA------------DILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSH 422          

Query:  262 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFY---KKSESE------------RNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTS----------LPYVKADFIQIIYYITV---SILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLI----ASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSH--FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTH 1461
            DSE   V  +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  VLN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      + L   ++      K SE E            + +I      +  IW + ++P SS+ A     V    +   +  F + T   +     ++ I RN+T           L   + +     +YI     +  TF+++ R I   N    I S   IID ++ + FY +L+    AS++E              D+++   I  ++R F++ R   G ++L+ T + SA +L L++ F+++ +++F+S+++Y E   P+ H  F +IP   WW +VT+TT GYGDM PKT +G  V  +C+L GVL IA  VP++V+NF +YY+H
Sbjct:   22 DSENRVV--LNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDM-----RVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENA------------DILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSH 437          

Query:  100 EESSVVKINVRGVRFKVFWNTIKEIPG-----LSKTILEKGLHNKT-----KNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERN-------------SIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKA----DFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYY--NLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVT 1455
            E+S  + INV G R + + +T++ IPG     L+ T  +      T      +E+FFDR P +F  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  FE    + +E +++             S  C   ++  IW + E P SS  A + + V    ++  +  F + T  +        + K    S   ++       + ++  I V   TF+ + R I C N    I +   IID ++++PFY   +LI +  +    +  F        ++V+    +LR F++ R + G +VL +T++ S N+  L+++F+ + +L+F+++I+Y E     PD       +HF NIP  FWW +VT+TT GYGDMVPKT LG +V  +C++ GVL IA  VP++VNNF +YY+ A    +       +N   G +  + G   +    S +    +     ++ EN+T
Sbjct:   33 EDSDKIIINVGGTRHETYRSTLRTIPGSRLAWLADTDSQVNPDADTGQTHPNSEFFFDRHPGIFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDIFEPPDPEDAEDDQDMPRRFGIEDSPDRSRGCCEVWQPKIWALFEDPYSSRAARVIAFVSLFFILVSITNFCLETHEAFFEFHNHTDTKSATNSTTIIQVMDTKPVLTVVEGICVVWFTFEFLVRIICCPNKLLFIKNQLNIIDFVAILPFYLERSLIGNTSKAAKDVLGF--------LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFCLLIIFLALGVLIFATMIYYAERISADPDDPSGCNHTHFKNIPIGFWWAVVTMTTLGYGDMVPKTWLGMIVGALCAIAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHNPNPGMVLDS-GSFGKSESNSPRNSTQSDTCPLAAEENIT 512          

Query:  100 EESSVVKINVRGVRFKVFWNTIKEIPG-----LSKTILEKGLHNKT-----KNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERN-------------SIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKA----DFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYY--NLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVT 1455
            E+S  + INV G R + + +T++ IPG     L+ T  +      T      +E+FFDR P +F  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  FE    + +E +++             S  C   ++  IW + E P SS  A + + V    ++  +  F + T  +        + K    S   ++       + ++  I V   TF+ + R I C N    I +   IID ++++PFY   +LI +  +    +  F        ++V+    +LR F++ R + G +VL +T++ S N+  L+++F+ + +L+F+++I+Y E     PD       +HF NIP  FWW +VT+TT GYGDMVPKT LG +V  +C++ GVL IA  VP++VNNF +YY+ A    +       +N   G +  + G   +    S +    +     ++ EN+T
Sbjct:   33 EDSDKIIINVGGTRHETYRSTLRTIPGSRLAWLADTDSQVNPDADTGQTHPNSEFFFDRHPGIFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDIFEPPDPEDAEDDQDMPRRFGIEDSPDRSRGCCEVWQPKIWALFEDPYSSRAARVIAFVSLFFILVSITNFCLETHEAFFEFHNHTDTKSATNSTTIIQVMDTKPVLTVVEGICVVWFTFEFLVRIICCPNKLLFIKNQLNIIDFVAILPFYLERSLIGNTSKAAKDVLGF--------LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFCLLIIFLALGVLIFATMIYYAERISADPDDPSGCNHTHFKNIPIGFWWAVVTMTTLGYGDMVPKTWLGMIVGALCAIAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHNPNPGMVLDS-GSFGKSESNSPRNSTQSDTCPLAAEENIT 512          

Query:  100 EESSVVKINVRGVRFKVFWNTIKEIPG-----LSKTILEKGLHNKT-----KNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERN-------------SIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKA----DFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYY--NLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVT 1455
            E+S  + INV G R + + +T++ IPG     L+ T  +      T      +E+FFDR P +F  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  FE    + +E +++             S  C   ++  IW + E P SS  A + + V    ++  +  F + T  +        + K    S   ++       + ++  I V   TF+ + R I C N    I +   IID ++++PFY   +LI +  +    +  F        ++V+    +LR F++ R + G +VL +T++ S N+  L+++F+ + +L+F+++I+Y E     PD       +HF NIP  FWW +VT+TT GYGDMVPKT LG +V  +C++ GVL IA  VP++VNNF +YY+ A    +       +N   G +  + G   +    S +    +     ++ EN+T
Sbjct:   33 EDSDKIIINVGGTRHETYRSTLRTIPGSRLAWLADTDSQVNPDADTGQTHPNSEFFFDRHPGIFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDIFEPPDPEDAEDDQDMPRRFGIEDSPDRSRGCCEVWQPKIWALFEDPYSSRAARVIAFVSLFFILVSITNFCLETHEAFFEFHNHTDTKSATNSTTIIQVMDTKPVLTVVEGICVVWFTFEFLVRIICCPNKLLFIKNQLNIIDFVAILPFYLERSLIGNTSKAAKDVLGF--------LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFCLLIIFLALGVLIFATMIYYAERISADPDDPSGCNHTHFKNIPIGFWWAVVTMTTLGYGDMVPKTWLGMIVGALCAIAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHNPNPGMVLDS-GSFGKSESNSPRNSTQSDTCPLAAEENIT 512          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPG------LSKTILEKGL-----------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESER----------NSIKCVSHFRQ---MIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVT----SLPYVKADFIQIIYYITVSIL--TFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD----SH---FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +E   V +NV G R + + +T+K +PG       S++ LE  L           ++   NEYFFDR P VF  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  FE     + + E           ++   VS +R+   +IW + + P SS  A   +      +M  +  F + T  +    I K +  RN T    S  Y       + Y   V +L  TF+ + R  F  +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+    SH   F NIP  FWW +VT+TT GYGDM P+T  G +V  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GKFDERERVILNVGGTRHETYRSTLKTLPGTRLALLASESDLELVLDQLQQVPGFIEYSARSNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGID-ETDVEPCCWMTYRQHRDAEEALDVFEMNVDTEEDDEYGKRLGIEDVVSADGTVSRWRRWQPVIWNLFDDPYSSRAARFIAFASLFFIMVSITTFCLETHEAFNTIINKTDPLRNETLTDISQQYEIETDPALTYVEGVCVLWFTFEFLVRITFSPDKLEFIKSVLNIIDFVAILPFYLEVGLSGLSSK---------AAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPNDPTASHHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 441          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPG------LSKTILEKGL-----------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESER----------NSIKCVSHFRQ---MIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVT----SLPYVKADFIQIIYYITVSIL--TFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD----SH---FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +E   V +NV G R + + +T+K +PG       S++ LE  L           ++   NEYFFDR P VF  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  FE     + + E           ++   VS +R+   +IW + + P SS  A   +      +M  +  F + T  +    I K +  RN T    S  Y       + Y   V +L  TF+ + R  F  +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+    SH   F NIP  FWW +VT+TT GYGDM P+T  G +V  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GKFDERERVILNVGGTRHETYRSTLKTLPGTRLALLASESDLELVLDQLQQVPGFIEYSARSNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGID-ETDVEPCCWMTYRQHRDAEEALDVFEMNVDTEEDDEYGKRLGIEDVVSADGTVSRWRRWQPVIWNLFDDPYSSRAARFIAFASLFFIMVSITTFCLETHEAFNTIINKTDPLRNETLTDISQQYEIETDPALTYVEGVCVLWFTFEFLVRITFSPDKLEFIKSVLNIIDFVAILPFYLEVGLSGLSSK---------AAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPNDPTASHHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMVVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 441          

Query:   13 FLNRYSTLKPYRRT------GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIK-CVSH----------FRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVST------------VNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIME----ESESVKGNTNYATHRQNCATIDN 1506
            F  R S  KP  ++      G +E+S  + INV G+R + + +T+K +PG   + L +        ++   +E+FFDR P+VF  VLN  R G++H P  +CGPL+  E+  WGI  E  VE CC MN        + L +FE     + E + +  + C+             +  +W + E P SS       A  Y+A     F+ +  T            VN+      +  I R  T L      F+  +  I V   TF+ + R IFC +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  PD       + F NIP  FWW +VT+TT GYGDM P T  G LV  +C+L GVL IA  VP++VNNF +YY+ A    +             HI R            K    + HR     +  +    I+E    +S+      N A   ++C TID 
Sbjct:   10 FRGRKSGNKPPSKSCLKGDMGKNEDSDKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGDLKRLCLQEDGRKLGRWKRLQPKVWALFEDPYSSK------AARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNK------HIPRP--PQPGSPNYCKPDLQSPHRSAQGDACPLAQEEIIEINRADSKQNGDAANAALANEDCPTIDQ 534          

Query:   13 FLNRYSTLKPYRRT------GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIK-CVSH----------FRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVST------------VNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIME----ESESVKGNTNYATHRQNCATIDN 1506
            F  R S  KP  ++      G +E+S  + INV G+R + + +T+K +PG   + L +        ++   +E+FFDR P+VF  VLN  R G++H P  +CGPL+  E+  WGI  E  VE CC MN        + L +FE     + E + +  + C+             +  +W + E P SS       A  Y+A     F+ +  T            VN+      +  I R  T L      F+  +  I V   TF+ + R IFC +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  PD       + F NIP  FWW +VT+TT GYGDM P T  G LV  +C+L GVL IA  VP++VNNF +YY+ A    +             HI R            K    + HR     +  +    I+E    +S+      N A   ++C TID 
Sbjct:   10 FRGRKSGNKPPSKSCLKGDMGKNEDSDKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGDLKRLCLQEDGRKLGRWKRLQPKVWALFEDPYSSK------AARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNK------HIPRP--PQPGSPNYCKPDLQSPHRSAQGDACPLAQEEIIEINRADSKQNGDAANAALANEDCPTIDQ 534          

Query:   13 FLNRYSTLKPYRRT------GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIK-CVSH----------FRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVST------------VNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIME----ESESVKGNTNYATHRQNCATIDN 1506
            F  R S  KP  ++      G +E+S  + INV G+R + + +T+K +PG   + L +        ++   +E+FFDR P+VF  VLN  R G++H P  +CGPL+  E+  WGI  E  VE CC MN        + L +FE     + E + +  + C+             +  +W + E P SS       A  Y+A     F+ +  T            VN+      +  I R  T L      F+  +  I V   TF+ + R IFC +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  PD       + F NIP  FWW +VT+TT GYGDM P T  G LV  +C+L GVL IA  VP++VNNF +YY+ A    +             HI R            K    + HR     +  +    I+E    +S+      N A   ++C TID 
Sbjct:   10 FRGRKSGNKPPSKSCLKGDMGKNEDSDKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGDLKRLCLQEDGRKLGRWKRLQPKVWALFEDPYSSK------AARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNK------HIPRPPQPGSP--NYCKPDLQSPHRSAQGDACPLAQEEIIEINRADSKQNGDAANAALANEDCPTIDQ 534          

Query:   13 FLNRYSTLKPYRRT------GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIK-CVSH----------FRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVST------------VNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIME----ESESVKGNTNYATHRQNCATIDN 1506
            F  R S  KP  ++      G +E+S  + INV G+R + + +T+K +PG   + L +        ++   +E+FFDR P+VF  VLN  R G++H P  +CGPL+  E+  WGI  E  VE CC MN        + L +FE     + E + +  + C+             +  +W + E P SS       A  Y+A     F+ +  T            VN+      +  I R  T L      F+  +  I V   TF+ + R IFC +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  PD       + F NIP  FWW +VT+TT GYGDM P T  G LV  +C+L GVL IA  VP++VNNF +YY+ A    +             HI R            K    + HR     +  +    I+E    +S+      N A   ++C TID 
Sbjct:   10 FRGRKSGNKPPSKSCLKGDMGKNEDSDKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGDLKRLCLQEDGRKLGRWKRLQPKVWALFEDPYSSK------AARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNK------HIPRP--PQPGSPNYCKPDLQSPHRSAQGDACPLAQEEIIEINRADSKQNGDAANAALANEDCPTIDQ 534          

Query:   13 FLNRYSTLKPYRRT------GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIK-CVSH----------FRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVST------------VNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIME----ESESVKGNTNYATHRQNCATIDN 1506
            F  R S  KP  ++      G +E+S  + INV G+R + + +T+K +PG   + L +        ++   +E+FFDR P+VF  VLN  R G++H P  +CGPL+  E+  WGI  E  VE CC MN        + L +FE     + E + +  + C+             +  +W + E P SS       A  Y+A     F+ +  T            VN+      +  I R  T L      F+  +  I V   TF+ + R IFC +    I S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  PD       + F NIP  FWW +VT+TT GYGDM P T  G LV  +C+L GVL IA  VP++VNNF +YY+ A    +             HI R            K    + HR     +  +    I+E    +S+      N A   ++C TID 
Sbjct:   10 FRGRKSGNKPPSKSCLKGDMGKNEDSDKIVINVGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKTDEFFFDRHPQVFAYVLNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPTEEEEDGDLKRLCLQEDGRKLGRWKRLQPKVWALFEDPYSSK------AARYIAFASLFFILISITTFCLETHEAFNDVNNKTEVFTQGNITRTETILEMETEPFLTYVEGICVIWFTFEFLIRVIFCPDKMEFIKSSLNIIDFVAILPFYLEIGLSGLSSK---------AAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAAPDDITGSKHTDFKNIPIGFWWAVVTMTTLGYGDMYPVTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNK------HIPRP--PQPGSPNYCKPDLQSPHRSAQGDACPLAQEEIIEINRADSKQNGDAANAALANEDCPTIDQ 534          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R +FC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R +FC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  136 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH-NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYK-KSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV--NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGAN 1461
            +  +  ++ +NV G RF+ +  T++  P       EK    N+   EYFFDRDPEVF+CVLN  R G++H P   C   ++ E+  +GI +   +  CC     +     +   N E+      SE+ + S+  +S FRQ +W+  E P +S+LAL++  V    +   +   VV TV   +VP + +    +R      Y  A F   +    V I T + + R     +    I S  +IIDV++++P+Y  L+ +  E  +  F             L +  V R F+  R  +G ++L YT+K  A++L  ++  + +A+++F++V+FY E     S F +IP SFW+ IVT+TT GYGDMVPKT  G +   ICSL GVL+IA  VP++V+NF   Y               +       +RA  K +  R +  KT  +N
Sbjct:   35 NKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGI-LPEIIGDCCYEEYKD-----RKRENAERLMDDNDSENNQESMPSLS-FRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGER------YSVAFFC--LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFV-----------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---------------HQNQRADKRRAQKKARLARIRVAKTGSSN 439          

Query:  136 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH-NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYK-KSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV--NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGAN 1461
            +  +  ++ +NV G RF+ +  T++  P       EK    N+   EYFFDRDPEVF+CVLN  R G++H P   C   ++ E+  +GI +   +  CC     +     +   N E+      SE+ + S+  +S FRQ +W+  E P +S+LAL++  V    +   +   VV TV   +VP + +    +R      Y  A F   +    V I T + + R     +    I S  +IIDV++++P+Y  L+ +  E  +  F             L +  V R F+  R  +G ++L YT+K  A++L  ++  + +A+++F++V+FY E     S F +IP SFW+ IVT+TT GYGDMVPKT  G +   ICSL GVL+IA  VP++V+NF   Y               +       +RA  K +  R +  KT  +N
Sbjct:   35 NKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGI-LPEIIGDCCYEEYKD-----RKRENAERLMDDNDSENNQESMPSLS-FRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGER------YSVAFFC--LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFV-----------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---------------HQNQRADKRRAQKKARLARIRVAKTGSSN 439          

Query:  136 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH-NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYK-KSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV--NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGAN 1461
            +  +  ++ +NV G RF+ +  T++  P       EK    N+   EYFFDRDPEVF+CVLN  R G++H P   C   ++ E+  +GI +   +  CC     +     +   N E+      SE+ + S+  +S FRQ +W+  E P +S+LAL++  V    +   +   VV TV   +VP + +    +R      Y  A F   +    V I T + + R     +    I S  +IIDV++++P+Y  L+ +  E  +  F             L +  V R F+  R  +G ++L YT+K  A++L  ++  + +A+++F++V+FY E     S F +IP SFW+ IVT+TT GYGDMVPKT  G +   ICSL GVL+IA  VP++V+NF   Y               +       +RA  K +  R +  KT  +N
Sbjct:   35 NKRQDELIVLNVSGRRFQTWRTTLERYPDTLLGSTEKEFFFNEDTKEYFFDRDPEVFRCVLNFYRTGKLHYPRYECISAYDDELAFYGI-LPEIIGDCCYEEYKD-----RKRENAERLMDDNDSENNQESMPSLS-FRQTMWRAFENPHTSTLALVFYYVTGFFIAVSVITNVVETVPCGTVPGSKELPCGER------YSVAFFC--LDTACVMIFTVEYLLRLFAAPSRYRFIRSVMSIIDVVAIMPYYIGLVMTNNEDVSGAFV-----------TLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAIIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSNFSRIY---------------HQNQRADKRRAQKKARLARIRVAKTGSSN 439          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R IFC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R +FC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---------------ESERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G  +ES  + INV G R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F       S               E E    K ++               ++  IW + E P SS  A   +      ++  +  F + T       + K EI+  RN T + Y +      F+  I  + V   TF+ + R +FC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 446          

Query:  262 DSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFY---KKSESE------------RNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTS----------LPYVKADFIQIIYYITV---SILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLI----ASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSH--FINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTH 1461
            DSE   V  +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  VLN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T      + L   ++      K SE E            + +I      +  IW + ++P SS+ A     V    +   +  F + T   +     ++ I RN+T           L   + +     +YI     +  TF+++ R I   N    I S   IID ++ + FY +L+    AS++E              D+++   I  ++R F++ R   G ++L+ T + SA +L L++ F+++ +++F+S+++Y E   P+ H  F +IP   WW +VT+TT GYGDM PKT +G  V  +C+L GVL IA  VP++V+NF +YY+H
Sbjct:    7 DSENRVV--LNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDM-----RVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENA------------DILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSH 422          

Query:  151 INVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSES----ERNSIKCVS--------------HFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVT--------SLPYVKADFIQIIYYITVSI---LTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYN-LIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEG--EVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKK 1434
            +NV GVR + +  T+K+IP    + L   L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   +  E CC M L ++    + L   ++      +     E++++K                   +  +W + ++P SS  A + + +  L +   +F F + T  S  F +  L I +N+T        S+  V  + + I   I +      T +LI R +FC +      S   +ID+++ + FY + ++   +E +            DV++ L +  + R F++ + ++G Q+L++T + SA +LIL++ F+++ +++F+++++Y E     P++ F +IP   WW I T+TT GYGDM P T  G LV  +C++ GVL IA  VP++V+NF ++Y+H          N   ++L    +R L  V+QIR ++++
Sbjct:   41 LNVGGVRHETYQATLKKIPATRLSRLTPSLANFDPLLNEYFFDRHPAVFAMILNYYRTGKLHYPTDVCGPLFEEELQYWGLDASD-TEPCCWMQLLHAKDTQETLAVLDRMDADHEDDPQLREQDTMKKFGWEEDYFQGKRTRWMKLKPQMWSLFDEPYSSQAAKLIAGISVLFIFISIFSFCLKTHQS--FRLPVL-IGQNITMPGGVVQPSIERVSTEPLPIFGQIEMLCNIWFTLELIIRFVFCPSKIRFFKSPLNMIDLVATLSFYADAMMVRVVEDEP----------KDVVEFLSMIRIFRLFKLTQHHQGLQILIHTFRASAKELILLVFFLILGIVIFAALVYYAEKMEANPNNQFQSIPLGLWWAICTMTTVGYGDMTPHTSFGRLVGSLCAVMGVLTIALPVPVIVSNFAMFYSH----------NQARDKLPKRRRRVL-PVEQIRLQARR 477          

Query:  163 SMKFLNRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESE-----------------RNSIKC-------VSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK-----------RNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTA-GTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE-----GEV----------------------PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAM--SSEQTITNYTYNQLEGHIKR-ALGKVKQIRK 1515
            +M F++  S  +      D++  S++++NV G RF+V  +T+     + + +L  G++   + EYFFDRDP VF  VL  CR GE+H+P  +CGPL  RE+  WGI+   +++ CC+ +L ++  R+ +L+ FE FF ++ E+E                  NS K        ++  R+  WK+L+ P+S   A +Y+ +L + V+  +F FV ST       + + EI+            +  +   +KAD++    +    +LTFD + R + C N  ++  + YT+ID+LS++PFY N +   +    + FS P + G  + I  L I+  +R  RI R YRG QVL+YT+K S  DL+LM VFV +  L+FS++IF+ E     GE                        DS F ++   FWW +VT+TT GYGD+VP+T  G +V   C+L G+LLIAFTVPILVN+F+LYY+H+ +   S  ++  Y    L   +   A GKVK+++K
Sbjct:   71 NMHFIDDGSLDELMADIEDADVLSLIRVNVGGRRFEVLKSTLMRQHFIYEKLLHDGVYRAGQEEYFFDRDPTVFNIVLWYCRYGELHVPHHLCGPLLERELALWGIQPAIEIQNCCVSHLMDTKSRLISLKQFENFFKEEMETEPVVPLDCIENDDFGGPTSNSSKGWQRVKAFLASLRRRCWKILDHPSSGFPATVYAVLLTITVLYAVFSFVASTSEQFQRLLTQREIQFYSNKHPSWYGNHTDAQTRIKADWLVFSDWFAFGVLTFDFLVRLLCCKNKLAYFKNAYTVIDLLSILPFYVNELLK-LTWGIIEFSEPNSFGVTEYIAFLKISLFVRLLRIGRHYRGLQVLIYTLKTSLRDLMLMGVFVALGTLLFSTLIFFCEKSRSGGETHLAPTAPPDKKKVDCSKCQKGDTDSKFNSMFDGFWWSLVTMTTVGYGDLVPQTSSGRIVGSACALSGLLLIAFTVPILVNHFMLYYSHSQIVHVSRNSVQEYATKALLAKVNSFAGGKVKKMKK 586          

Query:  163 SMKFLNRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESER-----------------------NSIKC-VSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK-----------RNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTA-GTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE-----GEV----------------------PDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAM--SSEQTITNYTYNQLEGHIKR-ALGKVKQIRK 1515
            +M F++  S  +      D++  S++++NV G RF+V  +T+     + + +L  G++   + EYFFDRDP VF  VL  CR GE+H+P  +CGPL  RE+  WGI    +V+ CC+ +L ++  R+ +L+ FE FF ++ E+E                          +K  ++  R+  WK+L+ P+S   A +Y+ +L + V+  +F FV ST       + + EI+            +  +   +KAD++    +    +LTFD + R + C N  ++  + YT+ID+LS++PFY N +   +    + FS P + G  + I  L I+  +R  RI R YRG QVL+YT+K S  DL+LM VFV +  L+FS++IF+ E     GE                        DS F ++   FWW +VT+TT GYGD+VP+T  G +V   C+L G+LLIAFTVPILVN+F+LYY+H+ +   S  ++  Y    L   +   A GKVK+++K
Sbjct:   71 NMHFIDDGSLDELMADIEDADVLSLIRVNVGGRRFEVLKSTLMRQHFIYEKLLHDGVYRAGQEEYFFDRDPTVFNIVLWYCRYGELHVPHHLCGPLLERELALWGIHPAIEVQNCCVSHLMDTKSRLISLKQFENFFKEEMETEPVVPLDCGENDDFGGPTSSSSKGWQRVKAFLASLRRRCWKILDHPSSGFPATVYAVLLTITVLYAVFSFVASTSEQFQRLLTQREIQFYSNKHPSWYGNHTDAQTRIKADWLVFSDWFAFGVLTFDFLVRLLCCKNKLAYFKNAYTVIDLLSILPFYVNELLK-LTWGIIEFSEPNSFGVTEYIAFLKISLFVRLLRIGRHYRGLQVLVYTLKTSLRDLMLMGVFVALGTLLFSTLIFFCEKSRSGGETHLAPTAPPDKKKVDCSKCQKGDTDSKFNSMFDGFWWSLVTMTTVGYGDLVPQTSSGRIVGSACALSGLLLIAFTVPILVNHFMLYYSHSQIVHVSRNSVQEYATKALLAKVNSFAGGKVKKMKK 586          

Query:  163 SVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESE------------------------RNSIK-CVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK-----------RNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEG----------------------------------EVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAM--SSEQTITNYTYNQLEGHIKR-ALGKVKQIRK 1446
             +V++NV G RF+V  +T+ +   +   +L  G++   + EY+FDRDP +FK VL  CR GE+H+P   CGPL  RE+  WG++   +++ CC+ +L ++  R+ +L+ FE FF ++ ESE                        R  +K  ++  R+  WK+L+ P+SS  A +Y+ +L + V+  +F FV ST +     +   EI             +  + P +K D++    +I   +LTFD   R +FC N  ++  + YTIID+LS++PFY N +  +             G  + I  L I   +R  RI R YRG QVL+YT++ S  DL+LM VFV +  L+FS++IF+ E                                   +  DS F ++   FWW +VT+TT GYGD+VP+T  G +V   C+L G+LLIAFTVPILVN+F+LYY+H+ +   S+ ++  Y    L   +   A GKVKQ+RK
Sbjct:  245 GLVRMNVSGTRFEVLRSTLLKQRHIYDKLLHDGIYRAAQQEYYFDRDPAIFKIVLWYCRYGELHVPHHYCGPLLERELALWGVQSVIEIQNCCVSHLMDTKSRLVSLKKFENFFKEEMESEPLLLPEGVEFDDPLDLDPAKAHGWRRRVKDALAALRRRCWKILDHPSSSFPAAVYAVILSVTVLYTVFSFVASTSDRFQRPMSPGEIAFYSAKHPAWYGNHTNTNPQIKVDWLTFPDWIAFGVLTFDFFVRLLFCKNKLAYFKNNYTIIDMLSILPFYVNELLKFFFGIIEFSDSNNFGLAEYISFLKIALFMRLLRIGRHYRGLQVLIYTLRTSFRDLMLMGVFVALGTLLFSTLIFFCEKSRNEPSSGGGGGKGGTVDCSKCPGGGGGGNGGGRQGTDSRFTSMFDGFWWSLVTMTTVGYGDLVPQTNAGRIVGSACALSGLLLIAFTVPILVNHFMLYYSHSQIVHVSKSSVQEYATKALLAKVNSFAGGKVKQMRK 745          

Query:  163 SVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHF--------------------------RQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLP-----------YVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--------------GEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAM--SSEQTITNYTYNQLEGHIKR-ALGKVKQIRK 1446
             ++++NV G RF+V  +T+ +   +   ++  G++   + EY+FDRDP++F  VL  CR GE+H+P   CGPL  RE+  WGI+   +++ CC+ ++ ++  R+ +L+ FE FF ++ E+E   I     F                          R+  WK+L+ P+SS  A +Y+ +L + V+  +F FV ST       +   E+    +  P            +K D++    +I   +LTFD + R + C N  ++  + YTIID+LS++PFY N +                G  + I  + IT  +R  RI R YRG QVL+YT++ S  DL+LM VFV +  L+FS++IF+ E               +VP + F+++   FWW +VT+TT GYGD+VP+T  G +V   C+L G+LLIAFTVPILVN+F+LYY+H+ +   S  ++  Y    L   +   A GKVK++R+
Sbjct:   42 GLIRLNVSGTRFEVLRSTLLKQRYVYDKLMHDGIYRAPQQEYYFDRDPDIFTIVLWYCRYGELHVPHHYCGPLLERELALWGIQPAIEIQNCCVSHVMDTKSRLVSLKKFENFFKEEMENEPLIIPTDHEFEEQNLLQDLQKSHGWQKRLKEALIAMRRRCWKILDHPSSSFPAAVYAVLLSITVLYTVFSFVASTSEHFQRLMTPREVAFYSSKHPSWYGNHTDGRSRIKVDWLVFPDWIGFGVLTFDFLVRLLCCRNKLAYFRNNYTIIDLLSILPFYVNELLKVCFGIIEFSDSSNFGLPEYIAFVKITLFMRLLRIGRHYRGLQVLIYTLRTSFRDLMLMGVFVALGTLLFSTLIFFCEKARSEGHQVGADDCSKVPRTVFMSMFDGFWWSLVTMTTVGYGDLVPQTNAGRIVGSACALSGLLLIAFTVPILVNHFMLYYSHSQIVHVSRNSVQEYATKALLAKVNSFAGGKVKRMRQ 523          

Query:  160 SEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEK-GLHNKTKNE-YFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFR--QMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADF-------IQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA----AMSSEQTITNYTYNQLEGHIKRALGKVKQIRKK 1458
            SE+  +V+INV G  F     TIK++P      L   G H     E Y+FDRDPE+F+ VLN  RLGE+H+P  +CGP   +E++ WG+  E  +E CC ++      +  +L +FE+FF  +    +   +C   +R    +W  L++P+SS  A +Y  ++ + V   LFVF+  T  +    +       N TS   V   +       ++ + Y+ V+  TFD++ R        + + S  T+I+++++IP+Y + ++ +I  +   +        DVI V  I  +LR F+ILR Y G QVL+YT++ S  DL+LM+ F+ +A L FS++I++ +     + F +IP SFWW I+T+TT GYGD  P  P G+LV   C+L GVL++AFTVPILVN+F+L+Y+H+    ++  E+ ++ Y      G++ +    +K+++ K
Sbjct:   49 SEDRQLVRINVGGSLFLTRQRTIKKMPNSRLGRLRTTGPHYLRDQEMYYFDRDPEIFRVVLNYHRLGELHLPLHVCGPSLEKELQYWGLP-EELIEKCCWVSYVQLKSQKYSLLDFERFFDDRMSPRKVGPRCPRCYRFLDAMWTFLDKPSSSKGAFLYGVIVAVFVFLSLFVFIAETHPAFQLPLNST----NETSTSDVGDHYERQPWPGLETLDYVCVAFFTFDILLRVCVTPQKVTFLISPMTVIEIIAVIPYYIDFVSHFIHAR---YGHKPNKYLDVIHVFRIFGILRVFKILRHYSGLQVLIYTLRTSLKDLLLMLTFIGIATLFFSTLIYFSDDR---TKFSSIPASFWWSIITMTTVGYGDFYPTRPWGYLVGSACALIGVLVVAFTVPILVNSFMLFYSHSQSILSVKREERLSRY---HGRGYVDQPPKILKELQLK 482          

Query:  259 PYRRTGDSEES----SVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHN---------KTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFE--------------------KFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSL---PYVKADFIQIIYYIT---VSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1479
            P +  G +E S      + +NV G R + + NT++ +PG    +L   L +         +  NEYFFDR P VF  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  F+                    +   ++  +++        ++ ++W + E P SS  A   +      +M  +  F + T  +    I K +  RN + L   P  + +    + Y+    V   TF+ + R  F  +    + S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+  L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    4 PGKVNGKAEPSKHGNERIILNVGGTRHETYRNTLRTLPGTRLALLATELPSSACAVTVRARANNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGID-ETDVEPCCWMTYRQHRDAEEALDVFDMNALGGGPEGPGGEDGDELGEAAEQREHADKERDTGWRRWQPVMWNLFEDPYSSRAARFVAFASLFFIMVSITTFCLETHEAFNTIINKTDALRNDSLLEVSPQYEIETDPALTYVEGVCVLWFTFEFLVRVTFSPDKLEFVKSVLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFFLLIIFLALGVLIFATMIYYAERIGANPNDPTASDHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 451          

Query:  259 ESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESE-------RNSIK--CVSH----------FRQMIWKVLEQPTSSSLA--LIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLE------IKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1452
            +S  + IN  G+R + + +T+K +PG   + L +        ++   +E+FFDR P  F  +LN  R G++H P  +CGPLF  E+  WGI  E  VE CC MN        + L +FE    +  E +          +K  C+            ++  IW + E P SS  A  + + ++L++ +   +  F + T  +      K E      + R   S   V   ++  +  + V   T ++  R IFC +      S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:   34 DSEKIVINCGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPNTFAFILNYYRTGKLHCPSDVCGPLFEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPEVPEDDPALTGGADGDLKRLCLQEDGRKPSWWSIWQPRIWNLFEDPYSSKYARYVAFGSLLFILIS--ISTFCLETHEAFNTIYNKTENVTVGNVTREEVSFEVVTDSWLTYVEGMCVIWFTIEVFTRVIFCPDKAEFFKSSLNIIDFVAILPFYLEVALSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPEDPTASAHTAFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 464          

Query:  259 INVRGVRFKVFWNTIKEIPGLSKTILEKGLHN--------KTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFE--------------------KFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSL---PYVKADFIQIIYYIT---VSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1434
            +NV G R + + NT++ +PG    +L   L +        +  NEYFFDR P VF  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M         + L  F+                    +   ++  +++        ++ ++W + E P SS  A   +      +M  +  F + T  +    I K +  RN + L   P  + +    + Y+    V   TF+ + R  F  +    + S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+  L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    9 LNVGGTRHETYRNTLRTLPGTRLALLATELPSSACQQVRARANNEYFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELSFWGID-ETDVEPCCWMTYRQHRDAEEALDVFDMNALGGGPEGPGGEDGDELGEAAEQREHADKERDTGWRRWQPVMWNLFEDPYSSRAARFVAFASLFFIMVSITTFCLETHEAFNTIINKTDALRNDSLLEVSPQYEIETDPALTYVEGVCVLWFTFEFLVRVTFSPDKLEFVKSVLNIIDFVAILPFYLEVGLSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFFLLIIFLALGVLIFATMIYYAERIGANPNDPTASDHTMFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 436          

Query:   13 SEESSVVKINVRGVRFKVFWNTIKEIPGLSKTIL-EKGLH-----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNF-----------------------------EKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIK--RNVTSLPYVKAD---FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYR------GFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVT------VFTIMEESESVKGNTNYAT-HRQNCATIDN 1458
             +E   V INV G+R + + +T++ +PG     L E   H     +   +E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F                              K        +  +      +++ +W + E P SS  A   +      ++  +  F + T  +    I + +I    N T + Y + +   F+  I  + V   TF+ + R  FC + +  I +   IID ++++PFY  +  S + ++            +   VLG   V+RF RILR ++      G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A    +             HI RA     Q+   +    G N  H ++ S+         V  +      V G    A    ++C  ID 
Sbjct:    4 GDEKDRVVINVGGIRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDAQIDEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHREAEEALDSFGGGPAELGNDDTDADGLGDPGDGDEELEMTKRLALGDAPDGKAGGLWQRWQRRVWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTDIDPVDNSTRI-YQETETEVFLTYIEGVCVVWFTFEFLMRVTFCPDKKKFIKNTLNIIDFVAILPFYLEVGLSGLSSK------------EAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAKPNDPRASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNK------HIPRA----PQLGSPNFCKSGMNSPHHSTQSDTCPLAAQDEVLEMNRADPKVNGEAAKAALANEDCPHIDQ 523          

Query:  259 ESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESE-------RNSIK--CVSH----------FRQMIWKVLEQPTSSSLA--LIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLE------IKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1452
            +S  + IN  G+R + + +T+K +PG   + L +        ++   +E+FFDR P  F  +LN  R G++H P  +CGPLF  E+  WGI  E  VE CC MN        + L +FE    +  E +          +K  C+            ++  IW + E P SS  A  + + ++L++ +   +  F + T  +      K E      + R   S   V   ++  +  + V   T ++  R IFC +      S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:   34 DSEKIVINCGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPNTFAFILNYYRTGKLHCPSDVCGPLFEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPEVPEDDPALTGGADGDLKRLCLQEDGRKPSWWSIWQPRIWNLFEDPYSSKYARYVAFGSLLFILIS--ISTFCLETHEAFNTIYNKTENVTVGNVTREEVSFEVVTDSWLTYVEGMCVIWFTIEVFTRVIFCPDKAEFFKSSLNIIDFVAILPFYLEVALSGLSSKA---------AKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPEDPTASAHTAFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 464          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFE------------------KFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLE---IKRNVTSLPYVKADFIQIIYYIT---VSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G S+E+  V INV G R + +  T++ +PG   + L +        ++   NE+FFDR P VF  +LN  R G++H P  +CGPLF  E+  WGI  E  VE CC MN        + L +FE                  +F   +   +   +  +  ++  +W + E P SS  A I +    L ++  +  F + T  +    + K E   I    T   YV  +   ++ Y+    V+  +F+ + R I C + +  I +   +ID ++++PFY  +  S + ++      P       ++V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++IFY E  G  P+       + F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:   30 GRSDENERVVINVGGTRHETYRGTLRTLPGTRLSWLTEPDAFANFDYDAKGNEFFFDRHPTVFAHILNYYRTGKLHCPSEVCGPLFEEELIFWGID-ETDVEPCCWMNYRQHRDAEEALVSFENPDINGNDEVNEDGEVSKRFGLDERSPDGGKLGFLRRWQPRMWALFEDPYSSRAARIVALASLLFILISITTFCLETHEAFNTVLNKTENYTINNVTTQKVYVDVETDPVLMYVEGVCVAWFSFEFLVRIICCPDKKVFIKNYLNVIDFVAILPFYLEVGLSSLTSK------PARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIFYAERFGANPNDPTASDHTSFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFSMYYSLA 463          

Query:  268 VKINVRGVRFKVFWNTIKEIPG-----LSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTV----NSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYY 1440
            V++NV G+  +V W T++ +P      L  T     L      ++   NEYFFDR P  F  VLN  R G +H+   +C   F +E+  WG+  E  +E CC         ++      E    ++ E +     C +  R+ +W++LE P SS       A   +A++  LF+ V+ST+    N++P    K E    + +    + + + I ++      T + + R +   N          +ID+++++P+Y  +  +  E+   +  F       V+++  I  +LR  ++ R   G Q L +T++ S N+L L+++F+ + +++FSS++F+ E + PD+ F +IP SFWW  +T+TT GYGD+ P T LG ++ G+C + GVL+IA  +PI+VNNF  +Y
Sbjct:    2 VRLNVGGLVHEVLWRTLERLPRTRLGRLHATNTHGALSELCDDYSIADNEYFFDRHPGAFASVLNFYRTGRLHMSEEMCALSFGQELDYWGVD-EIYLETCCQARYHQKKEQMSEELRREAESAREREGDEFEGTCCADKRRKLWELLENPNSSL------AAKGMAIVSILFI-VLSTIALSLNTLPDLQHKDEFSHIIDNPKLAQVEAVCIAWF------TMEYLLRFMSAPNKWKFFKGALNVIDLMAILPYYITIFLT--ESSRGVSQFQN--VRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEPDTKFHSIPASFWWATITMTTVGYGDIYPMTLLGKIIGGLCCIAGVLVIALPIPIIVNNFSEFY 389          

Query:  268 VKINVRGVRFKVFWNTIKEIPG--LSKTILEKGLHNK--------TKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKC-VSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYY 1440
            + +NV G R  +    +  +P   L+  ++  G   +           E+FFDRDP  F  +L+    GE+H+  + C   F +E+  WG+  +  ++ CC    +     +  +    +   + S +   + +      R  +W+++E+P SS LA        LA+  F F+ VVS+V     TI +L+           +   I  I  + +   T +   R     +    + S   ++D+L+++P++  L  + +    +      A     ++ L I  V R F++ R   G Q L Y +K S  +L L+++++ V + +FS++ + VE   P++ F +IP SFWW I+T+TT GYGD+ PKT LG + A +  LCG L IA  +  ++NNFV +Y
Sbjct:    2 LAVNVGGSRHVLRSELLARLPDSLLATLLVRPGAARRPAYDDFDPDSGEFFFDRDPRAFDRILDAYHFGEVHMDRSACPMCFKQEMDFWGVGADC-LDDCCRFRYSELQEELDEIVQMVETELRDSGTAGAAQRGRCERARVGVWQLMEKPDSSRLAR------SLALTSFAFI-VVSSVVMCLGTIPELQPGPGADGAAGEEHPTIAAIETVCIGWFTVEFALRFFSAPDRVKFMSSPMNVVDLLAVLPYFVVLALTEMGGSVMGL----ASMQQGVQALRIMRVARVFKLARHSSGLQTLTYALKSSFKELGLLLLYLGVGVYLFSALGYTVEQSHPETLFSSIPHSFWWAIITMTTVGYGDIYPKTELGKINAAVSFLCG-LAIALPIHPIINNFVKFY 390          

Query:   31 NRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLH--NKTKNEYFFDRDPEVFKCVLNLCRLG-EMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSV--PFTIQKLEIKRNVTSLPY--VKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYN---QLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIMEESESVKGNTNYATHRQN 1500
             RY   +P    G  +    V INV G+RF+    T+ + P       +K +   +  +NEYFFDR+   F  +L   + G  +  P ++   +F  E++ + +  E             +M+R +    + K      E E+   +  + F++ +W + E P SSS A   + V  L ++  + +F + T+        + K+    N T   Y  V AD   I+  I +   +F+L+ R   C +      +   IID+++++P++  L     E QT   +     +  +++V+ +  V R F++ R  +G Q+L +T+  S  +L L++ F+ + +++FSS +F+ E +   + F +IP +FWW +VT+TT GYGDM PKT  G +V  +C++ GVL ++  VP++V+NF  +Y       +QT+ ++ ++       H   A    +  R+            C  + E+    + + E E    N N AT +Q+
Sbjct:   24 ERYELARP----GGHDFCERVVINVSGLRFETQLRTLAQFPDTLLGDPQKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVSVPYDIFTEEVRFYDLGEE-------------TMLRYREDEGYVK------EPEKPLPE--NEFQRQVWLLFEYPESSSPARAIAIVSVLVILISIIIFCLETLPEFRDDADLYKVSYYTNGTHYFYHNVFADPFFIMETICIIWFSFELMVRFCACPSKVEFGKNLMNIIDIVAIVPYFITLGTEMAE-QTGSANGQQTMSLAILRVIRLVRVFRIFKLSRHSKGLQILGHTLHASMRELGLLIFFLFIGVILFSSAVFFAEVDSKKTEFQSIPDAFWWSLVTMTTVGYGDMSPKTVGGKIVGSLCAIAGVLTVSLPVPVIVSNFNYFYQRETEGEDQTVYSHVHSTPFHEATHADNAEANSELCRRSICSFSSFEKIDCKEADEHADEDSCV-EGELKLSNCNVATAQQH 496          

Query:  220 INVRGVRFKVFWNTIKEIPG--LSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLG-EMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQK----LEIKR-NVTSLPYVKADFIQIIYYITVSI----LTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTY 1434
            INV G+RF+    ++ + P   L          +  +NEYFFDR+   F  +L   + G  +  P  +   +F+ EIK + +  E   +F                   ++ F K+ E    S      F++ +W + E P SS+ A   + V  L ++  + +F + T+    F  +K    L  K  N T +  +        ++I  +I     +F+L+ R   C +      S   IID+++++P++  L     + Q    S   A +  +++V+ +  V R F++ R  +G Q+L  T+K S  +L L++ F+ + +++FSS +++ E +  +S F +IP +FWW +VT+TT GYGDM P T  G +V  +C++ GVL IA  VP++V+NF  +Y     + E    NY +
Sbjct:   32 INVSGLRFETQLKSLDQFPDTLLGNPSKRSRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVSIDVFSEEIKFYELGNEAMAKF-----------------QEDEGFIKEEEKPLPS----DEFQRQVWLLFEYPESSNPARGIAIVSVLVILISIIIFCLETLPE--FRDEKEQKFLPAKDINGTQVKIMHGSSFTDPFFIVETICIIWFSFELLVRFFACPSKPGFFKSIMNIIDIVAILPYFITLGTEMAKHQG---SGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADHQNSEFRSIPDAFWWAVVTMTTVGYGDMRPVTVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDNEEH--ANYLH 420          

Query:  259 YSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLS-KTILEKGLH----NKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESER-------------NSIK-----CVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1494
            +S L+     GD      V INV G + + +  T+K IP      I E G      +   +E+FFDR P VF  VLN  R G++H P  +CGPLF  E+  WGI  E +VE CC +N         NL  F+   +  S++E              +SI+         ++  IW + E+P SS  A + + +    ++  + +F + TV          +     TS  +V    + I+  + V+  T + + R IFC +  S        ID+ +++PFY  LI      +T++          V++V+ +  V R F++ R   G Q+L +T++ S ++L L++ F+ + +++FSSVIFY E +   +HF  IP +FWW +VT+TT GYGDMVP T  G +V  +C++CGVL+IA  VP++V+NF LYY+HA
Sbjct:    5 HSVLEEQTNAGDR-----VVINVGGQKHETYIGTLKNIPDTRLYWITENGTQLPEFDPNTSEFFFDRHPGVFAQVLNFYRTGKLHCPNDVCGPLFEDELAFWGID-ELQVEPCCWLNYKQHREAQANLDPFD---HHDSDNESVGDMDMSVYGLVADSIRQRNRTWWKKYQPRIWTMFEEPYSSIPAQVLAFITMFLIISSVCLFCLETVP---------KFDNPKTSEGFV----LYILEAVCVAWFTLEFLFRLIFCPDKLSFFKKPMNWIDLGAILPFYLTLIVRESNFKTIV----------VLRVVRLIRVFRIFKLSRHSYGLQILGHTLRSSCSELFLLVFFLTIGVVIFSSVIFYAEKDTKGTHFTTIPHTFWWAVVTMTTLGYGDMVPITWQGQIVGSLCAVCGVLMIALPVPVIVSNFSLYYSHA 407          

Query:  259 VKINVRGVRFKVFWNTIKEIPG-----LSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKK------------------SESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTN-DVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1440
            V INV GVR + + +T+K IP      +++        + +  EYFFDR P VF  VLN  R G++H P  +CGPLF  E+  WGI  + +VE CC +         + L  FE   ++                   +ESE +       ++  IW ++E+P SS+LA + +      ++  + +F + ++                 S  Y+K D + I+  I V   T +L+ R +FC             ID L+++PFY +L             F     + D + ++ +  + R F++ R   G Q+L +T++ S  +L+L++ F+++ +++F+S+IFY E ++P + F++IP SFWW +VT+TT GYGDM P++P G  +  +C++CGVL IA  VP++VNNF LYY+HA
Sbjct:    3 VSINVGGVRHETYKSTLKNIPDTRLSWIAEASAGAADFDPSTGEYFFDRHPGVFANVLNYYRTGKLHCPLDVCGPLFEDELGFWGID-DQQVESCCWLTYRQHRDAQETLAAFEGVEFENEYEDDEEPDLGRYGFNFAAESEPDKT-WWERYQPRIWTLMEEPHSSTLAKVIAYTTLTLILVSVGIFCLESMEKF--------------SEKYLK-DLLVILEGICVVWFTLELMVRFVFCPAKCEFFKKIMNWIDFLAIVPFYVSL------------GFNNNNNDIDALMIIRLIRIFRIFKLSRHSSGLQILGHTLRASFRELLLLIFFLLIGVVLFASLIFYCEKKIPGTKFVDIPSSFWWAVVTMTTVGYGDMAPQSPSGKFIGSLCAVCGVLTIALPVPVIVNNFSLYYSHA 391          

Query:  259 ESSVVKINVRGVRFKVFWNTIKEIPG--LSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESER-----------NSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHIC-SCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEG--EVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1452
            +SS + INV G R +   +T++ IP   LS       ++   K EYFFDR P  F  VLN  R G++H P  +CGP+F  E+  WGI  E ++E CC    T      +NL+ F    +   + E            N + C    +  +W+ L++P SS +A I+S    L +   +  F  +T+ +    I+K  I  +   L +++  F  I +       +F+L  R I C + + H C      ID +++IPFY N+             +P    N ++++  +  ++R FR ++   G Q+++ T+K S+++L+L+++ V++ +++FSS+++YVE   E   + F ++P+SFWWC++T+TT GYGDM P+T  G ++ G C++CGVL++A  + ++ +NF LYY HA
Sbjct:   14 DSSRIIINVGGFRHETSVSTLQNIPDTRLSWIAENSTVNEDNKREYFFDRHPTAFCQVLNFYRTGKLHCPTEMCGPMFEEELIFWGID-EKQMEPCCWGTYTQHREAEENLKAFVGPGFNDLKDEPAENHMGSYGSINELNCWKRIQPQLWETLDEPHSSKMAKIFSYTSCLFIALSIATFCATTMPA----IRKNNIMGSREGLDHIEM-FCSIFF-------SFELFMRLISCPS-KLHFCRGIMNWIDFVAIIPFYVNIF------------YP----NPIVRMFLVIRIMRLFRFIKLSYGLQIMIQTLKASSHELVLLLLMVLIPMVMFSSIVYYVEVIIEGRGAQFTSVPESFWWCLITMTTVGYGDMTPQTWPGKIIGGACAICGVLIVALPISVIGSNFNLYYAHA 397          

Query:  244 VKINVRGVRFKVFWNTIKEIP-------------GLSKTILEKGLHNKTKN-EYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFF-----YKKSESERN------SIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSE 1440
             ++N+ GVRF++ W++IKE P             G +   L  G+    K  E FF RDPE+FK ++   R G+ H P TIC   F RE+K WGI ++N  + CC  +       ++NL   ++ F      KK + E +      S   ++  ++ +W + E P SS +A I   +    VM       ++T++S+   +   E   N   L  ++A          ++  T + + R +    +   + S    ID+L+++P+Y+ L++   + Q     +       ++++L I  ++R F++ R   G Q L YT K S  +L L+   +++ + +FSS++++ E   P+S F +IP++FWW I+T+TT GYGD+ P TPLG LV  +C + G++ IA  +P +V+NF  +Y     S E
Sbjct:   15 AQLNISGVRFELLWSSIKEFPFTRLGKVYFWYEHGDNWQELCDGVKMGEKTAEVFFQRDPEIFKTIMCYYRNGKFHFPRTICIEHFQRELKYWGISIKNMGD-CCYNHFHQENEAVENLMKIKEAFKKDLNMKKEQDEVDLLLEVESRSKLARLKRKMWDLFENPHSSFMAKIVYLLSSFFVMLSTVALCLNTIDSLRIKLDNGETADNAV-LAGIEAG--------CIAWFTVEYLIRLLSAPRIVPFLKSIMNTIDLLAILPYYFELLSLAFDNQ---LDYRFVEMRRILQILRILRIVRIFKMARHSVGLQTLAYTFKQSTAELGLLGTLLIMGMTLFSSLVYFAEEAEPNSMFKSIPEAFWWSIITMTTVGYGDVYPVTPLGKLVGSLCCISGIIFIALPIPTIVSNFSQFYKDQRKSVE 425          

Query:  259 INVRGVRFKVFWNTIKEIPG-----LSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS---ESERNSIKCVSHFRQ-----------------MIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1434
            INV G R++ F +T+  IP      ++    E   ++ + NEYFFDR   +F+ +LN  R G++H P  +C  +F  E+  WGI  E ++E CC    T     I++LR F      +S   E+  N+  CV   R+                 +IW+ LE+P SS  A I + +    ++  +  FV+S+V  VP+            S P        +I Y+  S  TF+ I RT F  +LR       T +D+ +L+PFY                F   G  + IK+  +  +LR FR+ R     Q++   +K S ++L L+++ ++++++ FS+++FY +G+   S F NIPKSFWW I+T+TT GYGD  P +  G +V   C+L GVL+I   + I+ +NF LYY HA
Sbjct:   21 INVGGRRYETFQSTLASIPDTRLAWIAGRPHETPEYDTSHNEYFFDRHSAIFEDILNYYRTGKLHCPRGVCSAVFEEELSFWGID-EEQMEPCCWPEYTRQRTAIEDLRIFNGNASDESLNSENTLNNADCVLPGRKASEDRKGLRGFYRLVQPIIWRTLEEPFSSCTAKITAIISLAFILLSVLDFVMSSVPVVPYQ-----------STP-------SVIEYVCGSWFTFEFILRTAFSPSLRRQFKKPMTWVDIGALLPFYLQF-------------FIDVGDMERIKIFIMFRLLRVFRLFRFSYRLQIMALALKGSLHELGLLLLILVISVIFFSTLVFYTDGDNKRSKFQNIPKSFWWAIITLTTVGYGDDTPVSWSGRIVGSACALWGVLMITLPISIVNSNFSLYYAHA 405          

Query:  259 TGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSH-------------------FRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPY---------VKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTL--LFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1467
            T  + +S  + IN  G+R + + +T+K +PG   + L +        ++   +E+FFDR P  F  +LN  R G++H P  +CGPLF  E+  WGI  E  VE CC MN        + L +FE       E +     C                      ++  +W + E P SS  A   +      ++  +  F + T  +      K E   NVT   +         V   ++  +  + V   T +++AR IFC +      S   IID ++++PFY  +  S + ++T   + SF        ++V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 TCSASDSEKIVINCGGIRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPATFAFILNYYRTGKLHCPSDVCGPLFEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPDAPEDDPALTGCADGDLKRLCMQEDGRRATRWQVWQPWMWALFEDPYSSKYARYVAFASLFFILLSISTFCLETHEAFNTIYNKTE---NVTVGNFTHEEIVYEVVTDGWLTYVEGVCVIWFTIEVMARVIFCPDKAEFFRSALNIIDFVAIVPFYLEVALSGLSSKTAKDILSF--------LRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPNDPTAAAHTTFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 437          

Query:  259 SEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKG---------LHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFE------------KFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYIT---VSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTN--DVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1458
             E+S  + INV G R + + +T++ +PG     L +              +  E+F+DR P +F  VLN  R G++H P  +CGPLF  E+  WGI  E  VE CC M+          L  FE            + F  +  S+R S  C   ++  +W + + P SS  A   + V    ++  +  F + T ++    + K+    N +     +    +I++ +    V   T + + R I C N    I +   IID ++++PFY  +    + ++        A  N    ++V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       +HF NIP SFWW +VT+TT GYGDM P+T LG +V  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:   32 GEDSDKIVINVGGTRHETYKSTLRTLPGTRLAWLAEPDAQVSTDSVAEPPSAAEFFYDRHPGIFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGID-ETDVEPCCWMSYRQHRDAEAALEIFEPPDPDDTDDEAPRRFGIEDCSDR-SRSCCEVWQPKLWALFDDPYSSRAARGVAFVSLFFILLSITTFCLETHDAFNEWMDKVFQGNNTSGKSKAELGGSKILHGVEGVCVFWFTLEFLVRIICCPNKCFFIKNTLNIIDFVAILPFYLEMCLEGLSSK--------AAKNVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASVNEFLLLVIFLALGVLIFATMIYYAERIGASPNDPTGFNHTHFKNIPISFWWAVVTMTTLGYGDMYPQTWLGMMVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 456          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFE---------------------------KFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVK----------------ADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G S++   + INV G+R + + +T++ +PG   + L +        ++    E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F                            +   +    +  S    S +++ +W + E P SS  A       ++A+    F+ V  T     F ++  E    + +  YV+                A ++  I  + V   TF+ + R  FC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM PKT  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GLSDDKDRIVINVGGIRHQTYRSTLRTLPGTRLSWLAEPDAPNHFDYDAKIEEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHREAEEALDSFGGGGLLDLGSDDPDPEPEHTEDEVDEMTRRLAQGDSPDARSGSLWSRWQKRVWALFEDPYSSKYAR------WIALASLFFILVSITT----FCLETHEAFNPIVNRTYVEHLDNITTENTYQETETAAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSK---------AAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 444          

Query:  259 GDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFE---------------------------KFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVK----------------ADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1464
            G S++   + INV G+R + + +T++ +PG   + L +        ++    E+FFDR P VF  +LN  R G++H P  +CGPL+  E+  WGI  E  VE CC M         + L +F                            +   +    +  S    S +++ +W + E P SS  A       ++A+    F+ V  T     F ++  E    + +  YV+                A ++  I  + V   TF+ + R  FC N    I +   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  P+       + F NIP  FWW +VT+TT GYGDM PKT  G LV  +C+L GVL IA  VP++VNNF +YY+ A
Sbjct:    2 GLSDDKDRIVINVGGIRHQTYRSTLRTLPGTRLSWLAEPDAPNHFDYDAKIEEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGID-ETDVEPCCWMTYRQHREAEEALDSFGGGGLLDLGSDDPDPEPEHTEDEVDEMTRRLAQGDSPDARSGSLWSRWQKRVWALFEDPYSSKYAR------WIALASLFFILVSITT----FCLETHEAFNPIVNRTYVEHLDNITTENTYQETETAAYLTYIEGVCVVWFTFEFLMRITFCPNKFDFIRNALNIIDFVAILPFYLEVGLSGLSSK---------AAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGANPNDPRASDHTQFKNIPIGFWWAVVTMTTLGYGDMYPKTTFGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLA 444          

Query:  139 ESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGL------HNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKS------------------ESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFV------FVVSTVNSVPFTIQKLE------IKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVI---KVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE--GEVPD-------SHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYT--------------HAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGA 1452
            ES  + IN  GVR + + +T+K +PG   + L +        ++   +E+FFDR P VF  +LN  R G++H P  +CGPLF  E+  WGI  E  VE CC MN        + L +FE                         + +         ++  IW + E P SS  A       Y+A M   F+      F + T  +      K E      + R       V   ++  +  + V   T +++ R  FC +      S   IID ++++PFY  +  S + ++            DV+   +V+    +LR F++ R + G +VL +T++ S N+ +L+++F+ + +L+F+++I+Y E  G  PD       ++F NIP  FWW +VT+TT GYGDM P+T  G LV  +C+L GVL IA  VP++VNNF +YY+              H   + +    NY    L G    A  ++ +I + SK+   A
Sbjct:    6 ESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKLDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGID-ETDVEACCWMNYRQHRDAEEALDSFETPEPDAPDDDPALGGADGDLKRLCMQEDARRAGWWKTWQPRIWALFEDPYSSKYAR------YVAFMSLFFILISISTFCMETHEAFNTIYNKTENVTIGNVTREEIVYEVVTDSWLTYVEGVCVIWFTIEVLLRVTFCPDKLEFFKSALNIIDFVAILPFYLEVGLSGLSSK---------AAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYC---LGGDCPLAQEEIIEINRDSKQNGDA 486          

Query:    7 MGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIMEESESVKGNTNYATHRQNCATIDNFQ 969
            MGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLILMMVFVMVALLVFSSVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIMEESESVKGNTNYATHRQNCATIDNFQ
Sbjct:    1 MGFLFVFVVSTVNSVPFTIQKLEIKRNVTSLPYVKADFIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLILMMVFVMVALLVFSSVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKSKKTKGANHRHCNSSSENVTVFTIMEESESVKGNTNYATHRQNCATIDNFQ 321          

Query:   19 KPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVN----SVPFTIQKLEIKR--------------NVTSLPYVKADFIQI--IYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSEQTITNYTYNQLEGHIKRALGKVKQIRKKS----KKTKGANHRHCNSSSENVTVFTIME-ESESVKGNTNYATHRQNCATI 1482
            + Y++   ++  S V +NVRG RF++ W+T+K++P L   I  +G++ K+  EYFFDRDP+VFKC+LN CRLGE+H+P TICGP+F +E+  WGI   + +E+CCLM + NS+MR++NLR F+  F + +            FR  +W +L+QPTSSS ALIY+ +LYL V+G LFVF+  +V+    S PFT     IK               N T +   K   IQ+  I+  T S LTFD++AR IF     S I + YTIID+LSLIPFYYNLI +   ++  +     + +ND+I++L ++  LR FRILR YRG QVLLYT+KVS+ DL+LMM+F+ +A ++FS+++FYVE +  +  F NIP++FWWCIVTITTTGYGDMVP T +G+L+AG+C+LCGVL+IAFTVPILVNNF+LYYTHA+ + +  +  Y   Q+E H+K A+ +VK+++  +    KK    N    N+  EN   +T+   ++ S+ G     +H  +C T+
Sbjct:    6 EKYQQKDLTDPDSTVIVNVRGKRFELLWSTLKKLPDLENAIRIRGIYRKSLQEYFFDRDPDVFKCLLNYCRLGELHVPSTICGPIFTKELHAWGIMKVDNIEYCCLMGINNSLMRLENLRKFDNMFPESNTEIGTDYDKFVRFRLFVWNILDQPTSSSFALIYAIILYLTVLGSLFVFITDSVDHPTFSTPFTDVDYSIKYGWTSQQLSEILSWPNATKILNEKKRTIQMNAIFIATNSFLTFDMVARMIFTTKFCSFIMNPYTIIDILSLIPFYYNLIDTVSHSKRSINVAFFSQSNDLIRLLSLSIGLRCFRILRHYRGLQVLLYTIKVSSFDLLLMMIFISLATIIFSTLMFYVENKT-NPKFTNIPRAFWWCIVTITTTGYGDMVPITGVGYLIAGLCALCGVLVIAFTVPILVNNFILYYTHASQNRKSGLYEYARKQIEEHLKEAVFQVKKLKDITTSYPKKFLKINDGFSNAQDENACSYTLERFDASSISG----GSHSFDCGTL 513          

Query:  916 MKFLNRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVNSVPFT 1512
            MKFLNRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTS         V   A + + FV +    ++  +T
Sbjct:    1 MKFLNRYSTLKPYRRTGDSEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSKIPITQIGVVADKAKLPYSFVAIDKFYDAAGYT 199          

Query:  259 EESSVVKINVRGVRFKVFWNTIKEIP--GLSKTILEKGLHNKTKNEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTNSMMRIKNLRNFEKFFYKKSESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVST---VNSVPFTIQKLEIKRNVTSLPYVKAD-----FIQIIYYITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVEGEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHA 1455
            ++   V+INV G  F+   +T+ +IP   L++  +    +     EYFFDRDPE+FK VLN  R+GE+H+P  ICGPL  +E++ WG+  E  +E CC ++      +  +L +FE FF +  +   ++  C   + + +WK   +P+SS LA+IY+ ++ + V+  +F F+  +     S   T  K+E+   + +  +           Q I +  V   + DL  R +   N    + +  T+I+++S+IP+Y ++   YIE    ++    +G   V+ VL I  VLR  +ILR Y G QVL+YT++ S  DL+LM+ F+ VA L FS++I++V+ +   + F +IP  FWW I+T+TT GYGD+ PK   G++V   CSL GVL++AFTVPILVN+F+LYY+HA
Sbjct:   68 DDIRTVRINVGGTIFETLESTLHKIPESKLAQLNVHSVYYRSQLKEYFFDRDPEIFKVVLNYHRIGELHLPLHICGPLLEKELQYWGMP-EQIIEKCCWIHYIQLKSQKYSLVDFENFFSEYDDEPNDN--CCRTWTKYLWKTFNKPSSSKLAMIYAIIVSIFVILSIFAFIAESHPKFKSNQNTSSKVELIPALNNNEFANHGNSMWIGFQYIDFCCVGFFSVDLFIRFLCTPNRMKFLSNVITVIEIISVIPYYVDIFGHYIER---IYKIELSGFLKVVHVLRIFGVLRILKILRYYSGLQVLVYTLRSSYKDLLLMLTFIGVATLFFSTLIYHVDDQ---NVFTSIPAGFWWSIITMTTVGYGDIYPKYFGGYIVGSACSLVGVLVVAFTVPILVNSFMLYYSHA 467          

Query:  244 SEESSVVKINVRGVRFKVFWNTIKEIPGLSKTILEKGLHNKTK--NEYFFDRDPEVFKCVLNLCRLGEMHIPCTICGPLFNREIKEWGIRMENKVEFCCLMNLTN-----------SMMRIKNLRNFEKFFYKK----SESERNSIKCVSHFRQMIWKVLEQPTSSSLALIYSAVLYLAVMGFLFVFVVSTVN--SVPFTIQ---KLEIKRNVTSLPYVKADFIQ---IIYY---ITVSILTFDLIARTIFCDNLRSHICSCYTIIDVLSLIPFYYNLIASYIETQTLLFSFPTAGTNDVIKVLGITSVLRFFRILRQYRGFQVLLYTMKVSANDLIXXXXXXXXXXXXXXXVIFYVE----GEVPDSHFINIPKSFWWCIVTITTTGYGDMVPKTPLGFLVAGICSLCGVLLIAFTVPILVNNFVLYYTHAAMSSE 1458
            ++  + V +NV G+R + +  T+K+IP    + L + L N     NEYFFDR P VF  +LN  R G++H P  +CGPLF  E++ WG+   N+VE CC M  T              + I   R  E   YK+     E E N +     +R  IW VLE+P SS LA + S +    ++  +  F + T    S+P  +     + I  ++     +    IQ   + +Y   I  +  + +LI R I   + RS       IID+ +L+ FY ++   Y   +           + +I+ + I  ++R F++ R   G ++L+ T K SA +L L++ F++V + VF+++I+Y E     E+ D  F +IP   WW I T+TT GYGDMVPKT  G LV  +C++ GVL I+  VP++V+NF ++Y+H    S+
Sbjct:    2 TDAENRVILNVGGIRHETYKATLKKIPATRLSKLTEALANYDPMLNEYFFDRHPGVFAQILNYYRTGKLHYPTDVCGPLFEEELEFWGLD-SNQVEPCCWMTYTAHRSTQDTLQILDRIDIDTERTSESELYKRFGLEEEFEDNELSFWQKWRPRIWSVLEEPYSSVLAKLVSGIGISIILISIISFCMKTYPGYSIPLILNHTYNVSIGGDLFQSWSLSQKEIQPHTVFFYTECICNAWFSIELILRMIVTASCRSFFHDVLNIIDIFALLSFYIDVSFVYFNIEK----------SHLIEFMSILRIMRLFKLTRHISGLKILILTFKASAKELSLLVFFLVVFIAVFAALIYYAEKFTKNELND--FTSIPNGLWWAICTMTTVGYGDMVPKTYPGMLVGALCAVTGVLTISLPVPVIVSNFSMFYSHTQARSK 425