Choline-phosphate cytidylyltransferase
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035391 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754]) HSP 1 Score: 143.28 bits (360), Expect = 5.670e-42 Identity = 66/138 (47.83%), Postives = 91/138 (65.94%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 9 RPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 145
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754]) HSP 1 Score: 145.591 bits (366), Expect = 8.420e-42 Identity = 71/156 (45.51%), Postives = 97/156 (62.18%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ S G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPN-TYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754]) HSP 1 Score: 144.821 bits (364), Expect = 8.209e-41 Identity = 71/156 (45.51%), Postives = 97/156 (62.18%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ S G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754]) HSP 1 Score: 144.821 bits (364), Expect = 8.209e-41 Identity = 71/156 (45.51%), Postives = 97/156 (62.18%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ S G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Human
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:HGNC Symbol;Acc:HGNC:8754]) HSP 1 Score: 145.206 bits (365), Expect = 8.737e-41 Identity = 71/156 (45.51%), Postives = 97/156 (62.18%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ S G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Celegans
Match: pcyt-1 (Putative choline-phosphate cytidylyltransferase [Source:UniProtKB/Swiss-Prot;Acc:P49583]) HSP 1 Score: 150.984 bits (380), Expect = 1.227e-43 Identity = 71/171 (41.52%), Postives = 105/171 (61.40%), Query Frame = 3 Query: 108 AYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 A S +A R + + K I L +AE GRP+RIY +G++D+FH+GHAN Q K FP ++++ GV ++D KYK + + EER VRHCR+VDEV APW TVEFL ++DF HD PY + G D+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 38 APFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFP-NVYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIR 207
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Celegans
Match: pcyt-1 (Putative choline-phosphate cytidylyltransferase [Source:UniProtKB/Swiss-Prot;Acc:P49583]) HSP 1 Score: 150.599 bits (379), Expect = 1.845e-43 Identity = 71/171 (41.52%), Postives = 105/171 (61.40%), Query Frame = 3 Query: 108 AYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 A S +A R + + K I L +AE GRP+RIY +G++D+FH+GHAN Q K FP ++++ GV ++D KYK + + EER VRHCR+VDEV APW TVEFL ++DF HD PY + G D+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 46 APFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPN-VYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIR 215
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Celegans
Match: Y18H1A.11 (pep chromosome:WBcel235:I:680408:683257:1 gene:WBGene00021215.1 transcript:Y18H1A.11b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y18H1A.11) HSP 1 Score: 137.117 bits (344), Expect = 4.766e-40 Identity = 70/171 (40.94%), Postives = 100/171 (58.48%), Query Frame = 3 Query: 108 AYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 A S D E+ R + + I L A G+ RP+R+Y +GV+DMFHYGHAN FLQ K P ++++ GV +++ MK K + + EER ++RHCR+VDEV +PW + FL E ++DF HD PY DIYE+ + F+ ++RTE IST+ I I R Sbjct: 12 APFSDDVEVIKQREAIDYSTQITLEDAISGNVTRPVRVYADGVYDMFHYGHANQFLQIKQTLPN-VYLIVGVCSDEETMKNKGRTVQGEEERYEAIRHCRYVDEVYKASPWTCPIPFLKELKVDFMSHDALPYQGPAGEDIYEKHRTAGMFLETQRTEGISTSDSICRIIR 181
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Celegans
Match: Y18H1A.11 (pep chromosome:WBcel235:I:680408:683472:1 gene:WBGene00021215.1 transcript:Y18H1A.11a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y18H1A.11) HSP 1 Score: 137.502 bits (345), Expect = 2.407e-39 Identity = 70/171 (40.94%), Postives = 100/171 (58.48%), Query Frame = 3 Query: 108 AYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 A S D E+ R + + I L A G+ RP+R+Y +GV+DMFHYGHAN FLQ K P ++++ GV +++ MK K + + EER ++RHCR+VDEV +PW + FL E ++DF HD PY DIYE+ + F+ ++RTE IST+ I I R Sbjct: 12 APFSDDVEVIKQREAIDYSTQITLEDAISGNVTRPVRVYADGVYDMFHYGHANQFLQIKQTLP-NVYLIVGVCSDEETMKNKGRTVQGEEERYEAIRHCRYVDEVYKASPWTCPIPFLKELKVDFMSHDALPYQGPAGEDIYEKHRTAGMFLETQRTEGISTSDSICRIIR 181
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Celegans
Match: Y18H1A.11 (pep chromosome:WBcel235:I:681355:683257:1 gene:WBGene00021215.1 transcript:Y18H1A.11d.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:Y18H1A.11) HSP 1 Score: 111.694 bits (278), Expect = 6.611e-31 Identity = 54/126 (42.86%), Postives = 76/126 (60.32%), Query Frame = 3 Query: 243 MFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 MFHYGHAN FLQ K P ++++ GV +++ MK K + + EER ++RHCR+VDEV +PW + FL E ++DF HD PY DIYE+ + F+ ++RTE IST+ I I R Sbjct: 1 MFHYGHANQFLQIKQTLPN-VYLIVGVCSDEETMKNKGRTVQGEEERYEAIRHCRYVDEVYKASPWTCPIPFLKELKVDFMSHDALPYQGPAGEDIYEKHRTAGMFLETQRTEGISTSDSICRIIR 125
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Fly
Match: Pcyt2 (gene:FBgn0035231 transcript:FBtr0072742) HSP 1 Score: 147.517 bits (371), Expect = 5.399e-42 Identity = 64/148 (43.24%), Postives = 100/148 (67.57%), Query Frame = 3 Query: 171 IPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 I ++A G R +R+Y +G++D+FH GHA +QAK+ FP ++++ GV +++ ++ K + +M ER +VRHCR+VDE++PNAPW EF++EH+IDF HD PY +GGV DIY LK + F+ ++RTE +ST+ I+ I Sbjct: 65 ITYHMARAGKTTRRVRVYADGIYDLFHQGHARQLMQAKNVFP-NVYLIVGVCNDELTLRMKGRTVMNGFERYEAVRHCRYVDEIVPNAPWTLNEEFIEEHKIDFVAHDDIPYGAGGVNDIYAPLKAKGMFVATERTEGVSTSDIVARI 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0072741) HSP 1 Score: 137.117 bits (344), Expect = 4.100e-37 Identity = 63/166 (37.95%), Postives = 103/166 (62.05%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 S D E + R + + + I +A G R +R+Y +G++D+FH GHA +QAK+ FP ++++ GV +++ + K + +M ER VRHCR+VDE++ NAPW + EF+ +++IDF HD PY + G+ DIY LK + F+ ++RTE +ST+ I+ I Sbjct: 174 SHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPN-VYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARI 338
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0072738) HSP 1 Score: 137.117 bits (344), Expect = 4.100e-37 Identity = 63/166 (37.95%), Postives = 103/166 (62.05%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 S D E + R + + + I +A G R +R+Y +G++D+FH GHA +QAK+ FP ++++ GV +++ + K + +M ER VRHCR+VDE++ NAPW + EF+ +++IDF HD PY + G+ DIY LK + F+ ++RTE +ST+ I+ I Sbjct: 174 SHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPN-VYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARI 338
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0333396) HSP 1 Score: 137.117 bits (344), Expect = 4.100e-37 Identity = 63/166 (37.95%), Postives = 103/166 (62.05%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 S D E + R + + + I +A G R +R+Y +G++D+FH GHA +QAK+ FP ++++ GV +++ + K + +M ER VRHCR+VDE++ NAPW + EF+ +++IDF HD PY + G+ DIY LK + F+ ++RTE +ST+ I+ I Sbjct: 174 SHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPN-VYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARI 338
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Fly
Match: Pcyt1 (gene:FBgn0041342 transcript:FBtr0345365) HSP 1 Score: 137.117 bits (344), Expect = 4.100e-37 Identity = 63/166 (37.95%), Postives = 103/166 (62.05%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 S D E + R + + + I +A G R +R+Y +G++D+FH GHA +QAK+ FP ++++ GV +++ + K + +M ER VRHCR+VDE++ NAPW + EF+ +++IDF HD PY + G+ DIY LK + F+ ++RTE +ST+ I+ I Sbjct: 174 SHDEEAMLERDRCDYTQRITYQMARSGQTTRRVRVYADGIYDLFHQGHARQLMQAKNIFPN-VYLIVGVCNDELTHRMKGRTVMNGFERYEGVRHCRYVDEIVQNAPWTLSDEFIADNKIDFVAHDDIPYVTDGMDDIYAPLKARGMFVATERTEGVSTSDIVARI 338
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Zebrafish
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta a [Source:ZFIN;Acc:ZDB-GENE-061220-4]) HSP 1 Score: 147.517 bits (371), Expect = 2.762e-42 Identity = 67/150 (44.67%), Postives = 100/150 (66.67%), Query Frame = 3 Query: 183 VAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 ++ SHG RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ KYK +M +ER ++RHCR+VDEV+ +APW T +FL++H+IDF HD PY S G D+Y+ +K+ F+P+KRTE IST+ +I I R Sbjct: 37 TVDQASHGTPVDRPVRVYADGIFDLFHSGHARALMQAKNLFPN-TYLIVGVCSDELTHKYKGFTVMTEDERYEALRHCRYVDEVLRDAPWTLTQDFLEKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTKRTEGISTSDLITRIVR 185
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Zebrafish
Match: pcyt1bb (phosphate cytidylyltransferase 1, choline, beta b [Source:ZFIN;Acc:ZDB-GENE-051120-48]) HSP 1 Score: 140.584 bits (353), Expect = 2.050e-39 Identity = 68/151 (45.03%), Postives = 96/151 (63.58%), Query Frame = 3 Query: 171 IPLYVAEKGSHG-RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 + L A +G+ RP+R+Y +G+FD+FH GHA +QAK+ FP +V GV + KYK +M +ER ++ HCR+VDEV+ +APW T EFL +HRIDF HD PY S G D+Y+ +K+ F+ ++RTE IST+ II I R Sbjct: 57 VTLAQARRGTPAQRPVRVYADGIFDLFHSGHARALMQAKNLFPNTQLIV-GVCSDALTHKYKGYTVMTEDERYEALIHCRYVDEVVRDAPWTLTSEFLKKHRIDFVAHDDIPYTSAGSEDVYKHIKEAGMFVATQRTEGISTSDIITRIVR 206
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Zebrafish
Match: pcyt1ab (phosphate cytidylyltransferase 1, choline, alpha b [Source:ZFIN;Acc:ZDB-GENE-050522-114]) HSP 1 Score: 139.428 bits (350), Expect = 5.354e-39 Identity = 67/138 (48.55%), Postives = 86/138 (62.32%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FDMFH GHA +QAK FP +V G + K K+ +M +ER +V HCR+VDEV+ NAPW + EFL EHRIDF HD PY S G D+Y +K F P++RTE IST+ II I R Sbjct: 72 RPVRVYADGIFDMFHSGHARALMQAKCLFPNTYLIVGGCT-FKIVFKFDGFXVMNEDERYDAVCHCRYVDEVVRNAPWTLSPEFLAEHRIDFVAHDDIPYISAGTDDVYRHIKDAGMFAPTQRTEGISTSDIITRIVR 208
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Zebrafish
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha a [Source:ZFIN;Acc:ZDB-GENE-050417-108]) HSP 1 Score: 137.887 bits (346), Expect = 3.138e-38 Identity = 67/138 (48.55%), Postives = 86/138 (62.32%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FDMFH GHA +QAK FP +V GV + K K +M +ER +V HCR+VDEV+ NAPW T EFL +HRIDF HD PY S D+Y+ +K F P++RTE IST+ II I R Sbjct: 72 RPVRVYADGIFDMFHSGHARALMQAKCLFPNTHLIV-GVCSDDLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRNAPWTLTPEFLTKHRIDFVAHDDIPYSSADSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 208
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Zebrafish
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha a [Source:ZFIN;Acc:ZDB-GENE-050417-108]) HSP 1 Score: 137.887 bits (346), Expect = 3.138e-38 Identity = 67/138 (48.55%), Postives = 86/138 (62.32%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FDMFH GHA +QAK FP +V GV + K K +M +ER +V HCR+VDEV+ NAPW T EFL +HRIDF HD PY S D+Y+ +K F P++RTE IST+ II I R Sbjct: 72 RPVRVYADGIFDMFHSGHARALMQAKCLFPNTHLIV-GVCSDDLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRNAPWTLTPEFLTKHRIDFVAHDDIPYSSADSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 208
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Xenopus
Match: cmtm3 (CKLF-like MARVEL transmembrane domain containing 3 [Source:Xenbase;Acc:XB-GENE-1011270]) HSP 1 Score: 144.821 bits (364), Expect = 9.096e-41 Identity = 67/138 (48.55%), Postives = 92/138 (66.67%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +V SDE KYK +M ER ++RHCR+VDE+I +APW T EFL++H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ II I R Sbjct: 75 RPVRVYADGIFDLFHSGHARALMQAKNLFPNSYLLVGVCSDEL-THKYKGFTVMNETERYEALRHCRYVDEIITDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Xenopus
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:100496938]) HSP 1 Score: 139.043 bits (349), Expect = 1.649e-38 Identity = 74/179 (41.34%), Postives = 99/179 (55.31%), Query Frame = 3 Query: 138 ILRHQMGHFKPIPL--------------YVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 + RH MG +P P E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +V SDE K +M ER +V+HCR+VDEV+ NAPW + EFL++HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 46 VARHTMGVREPAPFSDELKVDRSKTYRRVSMEEAKLGTPIERPVRVYADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDEL-THNLKGFTVMNEAERYDAVQHCRYVDEVVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 223
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Xenopus
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:100496938]) HSP 1 Score: 139.043 bits (349), Expect = 2.279e-38 Identity = 74/179 (41.34%), Postives = 99/179 (55.31%), Query Frame = 3 Query: 138 ILRHQMGHFKPIPL--------------YVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 + RH MG +P P E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +V SDE K +M ER +V+HCR+VDEV+ NAPW + EFL++HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 67 VARHTMGVREPAPFSDELKVDRSKTYRRVSMEEAKLGTPIERPVRVYADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDEL-THNLKGFTVMNEAERYDAVQHCRYVDEVVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 244
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Xenopus
Match: PCYT1A (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:100496938]) HSP 1 Score: 138.658 bits (348), Expect = 2.477e-38 Identity = 74/179 (41.34%), Postives = 99/179 (55.31%), Query Frame = 3 Query: 138 ILRHQMGHFKPIPL--------------YVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 + RH MG +P P E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +V SDE K +M ER +V+HCR+VDEV+ NAPW + EFL++HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 34 VARHTMGVREPAPFSDELKVDRSKTYRRVSMEEAKLGTPIERPVRVYADGIFDLFHSGHARALMQAKNLFPNTHLIVGVCSDEL-THNLKGFTVMNEAERYDAVQHCRYVDEVVRNAPWTLSPEFLEKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Xenopus
Match: pcyt2 (phosphate cytidylyltransferase 2, ethanolamine [Source:NCBI gene;Acc:496753]) HSP 1 Score: 97.0561 bits (240), Expect = 7.467e-23 Identity = 44/131 (33.59%), Postives = 79/131 (60.31%), Query Frame = 3 Query: 213 IRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQII 605 +R++ +G +DM HYGH+N QA++ +++ GV +++ ++K P+ EER V+ + VDE++P AP++TT+E LD++ DF +H + D YEE+K R+ +RT+ +STT ++ Sbjct: 19 VRVWCDGCYDMVHYGHSNQLRQARAMGG---YLIVGVHTDEEISQHKGPPVFTQEERYKMVKAIKWVDEIVPGAPYVTTLETLDKYNCDFCVHGNDITLTVDGKDTYEEVKNAGRYRECQRTQGVSTTDLV 146 HSP 2 Score: 77.0258 bits (188), Expect = 8.761e-16 Identity = 46/141 (32.62%), Postives = 74/141 (52.48%), Query Frame = 3 Query: 219 IYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRK--PIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSP-YPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISRTLVE 632 IY+ G FD+FH GH + FL+ + +V+ G+ +++ YKRK PIM ER LSV CR+V EV+ AP+ + + LD ++D H + P +D Y E K++ F +++T I+ I + +E Sbjct: 211 IYVAGAFDLFHIGHID-FLEKVYSLAEKPYVIVGLHFDQEVNHYKRKNYPIMNIHERTLSVLACRYVAEVVIGAPYSVSADLLDHFKVDIVCHGKTDVLPDRDGSDPYAEPKRRAIFRVVDSGNSLTTDDIVQRIIKNRLE 350
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Mouse
Match: Pcyt1b (phosphate cytidylyltransferase 1, choline, beta isoform [Source:MGI Symbol;Acc:MGI:2147987]) HSP 1 Score: 143.28 bits (360), Expect = 1.219e-40 Identity = 65/138 (47.10%), Postives = 93/138 (67.39%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV + K+K +M ER ++RHCR+VDEVI +APW T EFL++H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ II I R Sbjct: 45 RPVRVYADGIFDLFHSGHARALMQAKTLFPNS-YLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVR 181
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Mouse
Match: Pcyt1b (phosphate cytidylyltransferase 1, choline, beta isoform [Source:MGI Symbol;Acc:MGI:2147987]) HSP 1 Score: 143.28 bits (360), Expect = 2.743e-40 Identity = 65/138 (47.10%), Postives = 93/138 (67.39%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV + K+K +M ER ++RHCR+VDEVI +APW T EFL++H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ II I R Sbjct: 75 RPVRVYADGIFDLFHSGHARALMQAKTLFPNS-YLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Mouse
Match: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform [Source:MGI Symbol;Acc:MGI:88557]) HSP 1 Score: 142.895 bits (359), Expect = 2.927e-40 Identity = 70/156 (44.87%), Postives = 95/156 (60.90%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Mouse
Match: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform [Source:MGI Symbol;Acc:MGI:88557]) HSP 1 Score: 142.895 bits (359), Expect = 2.927e-40 Identity = 70/156 (44.87%), Postives = 95/156 (60.90%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Mouse
Match: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform [Source:MGI Symbol;Acc:MGI:88557]) HSP 1 Score: 142.895 bits (359), Expect = 2.927e-40 Identity = 70/156 (44.87%), Postives = 95/156 (60.90%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. UniProt/SwissProt
Match: sp|P49583|PCY1_CAEEL (Putative choline-phosphate cytidylyltransferase OS=Caenorhabditis elegans OX=6239 GN=F08C6.2 PE=3 SV=2) HSP 1 Score: 150.599 bits (379), Expect = 2.347e-42 Identity = 71/171 (41.52%), Postives = 105/171 (61.40%), Query Frame = 3 Query: 108 AYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 A S +A R + + K I L +AE GRP+RIY +G++D+FH+GHAN Q K FP ++++ GV ++D KYK + + EER VRHCR+VDEV APW TVEFL ++DF HD PY + G D+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 46 APFSDEALAITTREAVDYSKKITLAMAEANEAGRPVRIYADGIYDLFHHGHANQLRQVKKMFPN-VYLIVGVCGDRDTHKYKGRTVTSEEERYDGVRHCRYVDEVYREAPWFCTVEFLKNLKVDFIAHDAIPYVAPGEEDLYEKFRREGMFLETERTEGVSTSDVVCRIIR 215
BLAST of Choline-phosphate cytidylyltransferase vs. UniProt/SwissProt
Match: sp|Q9ZV56|CCT1_ARATH (Choline-phosphate cytidylyltransferase 1 OS=Arabidopsis thaliana OX=3702 GN=CCT1 PE=1 SV=1) HSP 1 Score: 146.362 bits (368), Expect = 6.084e-41 Identity = 65/135 (48.15%), Postives = 92/135 (68.15%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYP--SGGVADIYEELKKQNRFIPSKRTENISTTQII 605 RP+R+Y +G++D+FH+GHA QAK FP +++ G +++ KYK + +M EER S+RHC+ VDEVIP+APW+ EFLD+H+ID+ HD PY SG D+YE +KK RF ++RTE IST+ II Sbjct: 33 RPVRVYADGIYDLFHFGHARSLEQAKLAFPNNTYLLVGCCNDETTHKYKGRTVMTAEERYESLRHCKWVDEVIPDAPWVVNQEFLDKHQIDYVAHDSLPYADSSGAGKDVYEFVKKVGRFKETQRTEGISTSDII 167
BLAST of Choline-phosphate cytidylyltransferase vs. UniProt/SwissProt
Match: sp|P49585|PCY1A_HUMAN (Choline-phosphate cytidylyltransferase A OS=Homo sapiens OX=9606 GN=PCYT1A PE=1 SV=2) HSP 1 Score: 144.821 bits (364), Expect = 3.942e-40 Identity = 71/156 (45.51%), Postives = 97/156 (62.18%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ S G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFP-NTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. UniProt/SwissProt
Match: sp|P19836|PCY1A_RAT (Choline-phosphate cytidylyltransferase A OS=Rattus norvegicus OX=10116 GN=Pcyt1a PE=1 SV=2) HSP 1 Score: 143.28 bits (360), Expect = 1.461e-39 Identity = 70/156 (44.87%), Postives = 96/156 (61.54%), Query Frame = 3 Query: 165 KPIPLYVAEKGSHG----RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 KP E+ G RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ +K +M ER +V+HCR+VDEV+ NAPW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 57 KPYVRVTMEEACRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPN-TYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. UniProt/SwissProt
Match: sp|Q811Q9|PCY1B_MOUSE (Choline-phosphate cytidylyltransferase B OS=Mus musculus OX=10090 GN=Pcyt1b PE=1 SV=2) HSP 1 Score: 143.28 bits (360), Expect = 1.919e-39 Identity = 65/138 (47.10%), Postives = 93/138 (67.39%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV + K+K +M ER ++RHCR+VDEVI +APW T EFL++H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ II I R Sbjct: 75 RPVRVYADGIFDLFHSGHARALMQAKTLFPNS-YLLVGVCSDDLTHKFKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGMFVPTQRTEGISTSDIITRIVR 211
BLAST of Choline-phosphate cytidylyltransferase vs. TrEMBL
Match: A0A044SQ69 (CTP_transf_like domain-containing protein OS=Onchocerca volvulus OX=6282 PE=4 SV=1) HSP 1 Score: 167.933 bits (424), Expect = 3.056e-47 Identity = 77/168 (45.83%), Postives = 112/168 (66.67%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 S D E+ R ++ + + I L +A G GRP+RIY +GV+D+FHYGHAN LQAK FP ++++V GV ++D +KYK + + ER VRHCR+VDEV NAPW TVEFL + +IDF HD PY + G AD+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 10 SDDPEIIAQRARIDYSRKITLEMARSGKAGRPVRIYADGVYDLFHYGHANQLLQAKCAFP-EVYLVVGVCGDEDTLKYKGRTVTSENERYEGVRHCRYVDEVYKNAPWFCTVEFLKDLKIDFIAHDAIPYVAPGDADLYEKFRREEMFLETQRTEGVSTSDVVCRIIR 176
BLAST of Choline-phosphate cytidylyltransferase vs. TrEMBL
Match: A0A183H245 (CTP_transf_like domain-containing protein OS=Onchocerca flexuosa OX=387005 GN=OFLC_LOCUS1555 PE=4 SV=1) HSP 1 Score: 167.162 bits (422), Expect = 4.752e-47 Identity = 76/168 (45.24%), Postives = 112/168 (66.67%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 S D E+ R ++ + + I L +A G GRP+RIY +GV+D+FHYGHAN LQAK FP +++++ GV ++D +KYK + + ER VRHCR+VDEV NAPW TVEFL + +IDF HD PY + G AD+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 61 SDDPEIIAQRARIDYSRKITLEMARSGKAGRPVRIYADGVYDLFHYGHANQLLQAKCAFP-EVYLIVGVCGDEDTLKYKGRTVTSENERYEGVRHCRYVDEVYKNAPWFCTVEFLKDLKIDFIAHDAIPYVAPGDADLYEKFRREEMFVETQRTEGVSTSDVVCRIIR 227
BLAST of Choline-phosphate cytidylyltransferase vs. TrEMBL
Match: A0A182E2S6 (CTP_transf_like domain-containing protein OS=Onchocerca ochengi OX=42157 GN=NOO_LOCUS2278 PE=4 SV=1) HSP 1 Score: 168.318 bits (425), Expect = 7.508e-47 Identity = 77/168 (45.83%), Postives = 112/168 (66.67%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 S D E+ R ++ + + I L +A G GRP+RIY +GV+D+FHYGHAN LQAK FP ++++V GV ++D +KYK + + ER VRHCR+VDEV NAPW TVEFL + +IDF HD PY + G AD+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 60 SDDPEIIAQRARIDYSRKITLEMARSGKAGRPVRIYADGVYDLFHYGHANQLLQAKCAFP-EVYLVVGVCGDEDTLKYKGRTVTSENERYEGVRHCRYVDEVYKNAPWFCTVEFLKDLKIDFIAHDAIPYVAPGDADLYEKFRREEMFLETQRTEGVSTSDVVCRIIR 226
BLAST of Choline-phosphate cytidylyltransferase vs. TrEMBL
Match: A0A238BYB1 (Cytidyltransferase domain protein OS=Onchocerca flexuosa OX=387005 GN=X798_02799 PE=4 SV=1) HSP 1 Score: 167.162 bits (422), Expect = 2.946e-46 Identity = 76/168 (45.24%), Postives = 112/168 (66.67%), Query Frame = 3 Query: 117 STDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 S D E+ R ++ + + I L +A G GRP+RIY +GV+D+FHYGHAN LQAK FP +++++ GV ++D +KYK + + ER VRHCR+VDEV NAPW TVEFL + +IDF HD PY + G AD+YE+ +++ F+ ++RTE +ST+ ++ I R Sbjct: 61 SDDPEIIAQRARIDYSRKITLEMARSGKAGRPVRIYADGVYDLFHYGHANQLLQAKCAFP-EVYLIVGVCGDEDTLKYKGRTVTSENERYEGVRHCRYVDEVYKNAPWFCTVEFLKDLKIDFIAHDAIPYVAPGDADLYEKFRREEMFVETQRTEGVSTSDVVCRIIR 227
BLAST of Choline-phosphate cytidylyltransferase vs. TrEMBL
Match: A0A3P3YAK3 (CTP_transf_like domain-containing protein OS=Plasmodiophora brassicae OX=37360 GN=PLBR_LOCUS4410 PE=4 SV=1) HSP 1 Score: 164.081 bits (414), Expect = 1.177e-45 Identity = 73/140 (52.14%), Postives = 103/140 (73.57%), Query Frame = 3 Query: 204 GRPIRIYIEGVFDMFHYGHANLFLQAKSYFPG-QIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYP--SGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 GRPIR++ +G+FD+FH+GHA + QAK+ FPG ++ +V G+ ++D +YK K +M EERI SVRHCRHVDE+I +PW+ T EFL++HRID+ HD PYP SG D+Y +K+Q F+P+KRTE IST+ +I+ I Sbjct: 67 GRPIRVFADGIFDLFHFGHARVLEQAKNIFPGHEVHLVVGICSDEDTHRYKGKTVMTEEERIESVRHCRHVDEIIERSPWVLTNEFLEKHRIDYVAHDDLPYPDASGAADDVYAFVKQQGMFVPTKRTEGISTSDLINRI 206
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Cavefish
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:103043836]) HSP 1 Score: 145.206 bits (365), Expect = 2.205e-41 Identity = 66/138 (47.83%), Postives = 93/138 (67.39%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +V SDE KYK +M +ER ++RHCR+VDEV+ +APW T EFL++H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ +I I R Sbjct: 55 RPVRVYADGIFDLFHSGHARALMQAKNLFPNSYLIVGVCSDEL-THKYKGFTVMTEDERYEALRHCRYVDEVVRDAPWTLTQEFLEKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDLITRIVR 191
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Cavefish
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:103043836]) HSP 1 Score: 145.206 bits (365), Expect = 2.269e-41 Identity = 66/138 (47.83%), Postives = 93/138 (67.39%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +V SDE KYK +M +ER ++RHCR+VDEV+ +APW T EFL++H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ +I I R Sbjct: 49 RPVRVYADGIFDLFHSGHARALMQAKNLFPNSYLIVGVCSDEL-THKYKGFTVMTEDERYEALRHCRYVDEVVRDAPWTLTQEFLEKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDLITRIVR 185
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Cavefish
Match: pcyt1aa (choline-phosphate cytidylyltransferase A [Source:NCBI gene;Acc:103040438]) HSP 1 Score: 142.895 bits (359), Expect = 3.045e-40 Identity = 72/154 (46.75%), Postives = 96/154 (62.34%), Query Frame = 3 Query: 162 FKPIPLYVAEKGSH-GRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 +K + + A++G+ RP+R+Y +G+FDMFH GHA +QAK FP +V SDE K K +M +ER +V HCR+VDEV+ NAPW T EFL +HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 57 YKRVSMEEAKRGTPPERPVRVYADGIFDMFHSGHARALMQAKGLFPNTHLIVGVCSDEL-THKLKGFTVMNEDERYDAVTHCRYVDEVVRNAPWTLTPEFLTKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 209
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Cavefish
Match: pcyt1ab (choline-phosphate cytidylyltransferase A-like [Source:NCBI gene;Acc:103031553]) HSP 1 Score: 142.51 bits (358), Expect = 3.201e-40 Identity = 71/151 (47.02%), Postives = 94/151 (62.25%), Query Frame = 3 Query: 171 IPLYVAEKGS-HGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 + L A +G+ RP+R+Y +G+FDMFH GHA +QAK FP +V GV + K K +M +ER +V HCR+VDEV+ +APW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 58 VSLEEARRGTPANRPVRVYADGIFDMFHSGHARALMQAKRLFPNTHLIV-GVCSDGLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRDAPWTLTAEFLTEHRIDFVAHDDIPYVSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 207
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Cavefish
Match: pcyt1ab (choline-phosphate cytidylyltransferase A-like [Source:NCBI gene;Acc:103031553]) HSP 1 Score: 142.51 bits (358), Expect = 3.201e-40 Identity = 71/151 (47.02%), Postives = 94/151 (62.25%), Query Frame = 3 Query: 171 IPLYVAEKGS-HGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 + L A +G+ RP+R+Y +G+FDMFH GHA +QAK FP +V GV + K K +M +ER +V HCR+VDEV+ +APW T EFL EHRIDF HD PY S G D+Y+ +K+ F P++RTE IST+ II I R Sbjct: 58 VSLEEARRGTPANRPVRVYADGIFDMFHSGHARALMQAKRLFPNTHLIV-GVCSDGLTHKLKGFTVMNEDERYDAVSHCRYVDEVVRDAPWTLTAEFLTEHRIDFVAHDDIPYVSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR 207
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Yeast
Match: PCT1 (Cholinephosphate cytidylyltransferase; a rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding; contains an element within the regulatory domain involved in both silencing and activation of enzymatic activity [Source:SGD;Acc:S000003434]) HSP 1 Score: 129.028 bits (323), Expect = 1.771e-35 Identity = 62/138 (44.93%), Postives = 86/138 (62.32%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RPIRIY +GVFD+FH GH Q K FP + ++ GV +K K K ++ ++R ++ HCR VDEV+PNAPW T EFL EH+ID+ HD PY S DIY+ +K+ +F+ ++RT +ST+ II I R Sbjct: 102 RPIRIYADGVFDLFHLGHMKQLEQCKKAFPN-VTLIVGVPSDKITHKLKGLTVLTDKQRCETLTHCRWVDEVVPNAPWCVTPEFLLEHKIDYVAHDDIPYVSADSDDIYKPIKEMGKFLTTQRTNGVSTSDIITKIIR 238
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Yeast
Match: ECT1 (Ethanolamine-phosphate cytidylyltransferase; catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases; inability of the null mutant to synthesize phosphatidylethanolamine and phosphatidylcholine from ethanolamine is functionally complemented by human PCYT2 [Source:SGD;Acc:S000003239]) HSP 1 Score: 78.5666 bits (192), Expect = 1.180e-17 Identity = 45/138 (32.61%), Postives = 73/138 (52.90%), Query Frame = 3 Query: 210 PIRIYIEGVFDMFHYGHANLFLQAK---SYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 P +++I+G FD H+GHA LQA+ S G+++ GV ++D K P+M + ER R R EV+ AP++T ++D+++ + +H D Y+ +K+ RF KRT +STT+II I Sbjct: 7 PDKVWIDGCFDFTHHGHAGAILQARRTVSKENGKLF--CGVHTDEDIQHNKGTPVMNSSERYEHTRSNRWCSEVVEAAPYVTDPNWMDKYQCQYVVHGDDITIDANGEDCYKLVKEMGRFKVVKRTYGVSTTEIIHRI 142
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Nematostella
Match: EDO39372 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SAC0]) HSP 1 Score: 135.191 bits (339), Expect = 5.582e-40 Identity = 59/135 (43.70%), Postives = 93/135 (68.89%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVA--DIYEELKKQNRFIPSKRTENISTTQII 605 RPIR+Y +G++D FH+GHA +QAK FP +++++ GV ++ K K +M +ER +S+ H R+VDEVI +APWI + +F+D H+IDF HD PY + G+ D+Y+++K +F+ ++RTE IST+ II Sbjct: 1 RPIRVYADGIYDCFHFGHARSLMQAKRAFPTEVYLMVGVCSDELTHKLKGFTVMTEDERYMSLLHSRYVDEVIRDAPWIVSPDFIDIHKIDFVAHDDIPYKTAGMQTDDVYKDIKAMGKFVATERTEGISTSDII 135
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Nematostella
Match: EDO31320 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SY83]) HSP 1 Score: 97.4413 bits (241), Expect = 8.849e-24 Identity = 49/133 (36.84%), Postives = 72/133 (54.14%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQII 605 + IR++ +G FDM H+GHAN QAK+ W+ GV + + K P+ EER VR + VDEVI NAP+ TT+E +D+H +F +H + D Y +K R+ KRT +STT ++ Sbjct: 11 KQIRVWTDGCFDMVHFGHANALRQAKAMGD---WLCVGVHSDAEIAHNKGPPVFNEEERYKMVRAIKWVDEVIENAPYTTTLETMDDHGCEFCVHGDDITLTADGTDTYHIVKDAGRYKECKRTAGVSTTNLV 140 HSP 2 Score: 69.3218 bits (168), Expect = 7.516e-14 Identity = 43/137 (31.39%), Postives = 69/137 (50.36%), Query Frame = 3 Query: 219 IYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRK--PIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSG-GVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 IY G FD+FH G + +AK+ +++ G+ ++ +YK PIM ER+LSV CR+VD+VI AP+ + E +D+ ++D +H +P + D Y +K F I+T I+ I R Sbjct: 207 IYTAGAFDLFHVGFLDFLEKAKALGD---YLIVGLHTDQIVNRYKGSNYPIMNLHERVLSVLACRYVDQVIIGAPYSVSQELIDQFKVDLVVHGNTPVMNDVNGEDPYRIPRKLGIFKTINSESTITTADIVARIIR 340
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Nematostella
Match: EDO25505 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWA4]) HSP 1 Score: 46.9802 bits (110), Expect = 2.049e-7 Identity = 20/46 (43.48%), Postives = 31/46 (67.39%), Query Frame = 3 Query: 474 IDFAMHDPSPYPSGGVA--DIYEELKKQNRFIPSKRTENISTTQII 605 IDF HD PY + G+ D+Y+++K +F+ ++RTE IST+ II Sbjct: 1 IDFVAHDDIPYKTAGMQTDDVYKDIKAMGKFVATERTEGISTSDII 46
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Medaka
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:101166014]) HSP 1 Score: 144.821 bits (364), Expect = 7.964e-42 Identity = 65/138 (47.10%), Postives = 95/138 (68.84%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ KYK +M +ER ++RHCR+VDEV+ +APW T +FLD+H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ II I R Sbjct: 49 RPVRVYADGIFDLFHSGHARALMQAKNLFPN-TYLLVGVCSDELTHKYKGFTVMTEQERYEALRHCRYVDEVLRDAPWTLTPKFLDKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDIITRIVR 185
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Medaka
Match: pcyt1ba (phosphate cytidylyltransferase 1, choline, beta [Source:NCBI gene;Acc:101166014]) HSP 1 Score: 144.436 bits (363), Expect = 3.799e-41 Identity = 65/138 (47.10%), Postives = 95/138 (68.84%), Query Frame = 3 Query: 207 RPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 RP+R+Y +G+FD+FH GHA +QAK+ FP +++ GV ++ KYK +M +ER ++RHCR+VDEV+ +APW T +FLD+H+IDF HD PY S G D+Y+ +K+ F+P++RTE IST+ II I R Sbjct: 49 RPVRVYADGIFDLFHSGHARALMQAKNLFPN-TYLLVGVCSDELTHKYKGFTVMTEQERYEALRHCRYVDEVLRDAPWTLTPKFLDKHKIDFVAHDDIPYSSAGSEDVYKHIKEAGMFVPTQRTEGISTSDIITRIVR 185
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Medaka
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:101157809]) HSP 1 Score: 140.969 bits (354), Expect = 9.400e-40 Identity = 70/154 (45.45%), Postives = 97/154 (62.99%), Query Frame = 3 Query: 162 FKPIPLYVAEKGSH-GRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 +K + + A++G+ RP+R+Y +G+FD+FH GHA +QAK FP +V GV + KYK +M +ER ++ HCR+VDEV+ NAPW T EFL +HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 38 YKRVTMEEAKRGTPPDRPVRVYADGIFDVFHSGHARALMQAKRLFPNTHLIV-GVCSDDLTHKYKGFTVMNEDERYDAITHCRYVDEVVRNAPWTLTPEFLAKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 190
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Medaka
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:101157809]) HSP 1 Score: 140.969 bits (354), Expect = 1.115e-39 Identity = 70/154 (45.45%), Postives = 97/154 (62.99%), Query Frame = 3 Query: 162 FKPIPLYVAEKGSH-GRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 +K + + A++G+ RP+R+Y +G+FD+FH GHA +QAK FP +V SD+ KYK +M +ER ++ HCR+VDEV+ NAPW T EFL +HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 57 YKRVTMEEAKRGTPPDRPVRVYADGIFDVFHSGHARALMQAKRLFPNTHLIVGVCSDDL-THKYKGFTVMNEDERYDAITHCRYVDEVVRNAPWTLTPEFLAKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 209
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Medaka
Match: pcyt1aa (phosphate cytidylyltransferase 1, choline, alpha [Source:NCBI gene;Acc:101157809]) HSP 1 Score: 141.739 bits (356), Expect = 1.394e-39 Identity = 70/154 (45.45%), Postives = 97/154 (62.99%), Query Frame = 3 Query: 162 FKPIPLYVAEKGSH-GRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISR 620 +K + + A++G+ RP+R+Y +G+FD+FH GHA +QAK FP +V GV + KYK +M +ER ++ HCR+VDEV+ NAPW T EFL +HRIDF HD PY S G D+Y+ +K F P++RTE IST+ II I R Sbjct: 57 YKRVTMEEAKRGTPPDRPVRVYADGIFDVFHSGHARALMQAKRLFPNTHLIV-GVCSDDLTHKYKGFTVMNEDERYDAITHCRYVDEVVRNAPWTLTPEFLAKHRIDFVAHDDIPYSSAGSDDVYKHIKDAGMFAPTQRTEGISTSDIITRIVR 209
BLAST of Choline-phosphate cytidylyltransferase vs. Planmine SMEST
Match: SMESG000055917.1 (SMESG000055917.1) HSP 1 Score: 386.726 bits (992), Expect = 1.845e-138 Identity = 181/190 (95.26%), Postives = 187/190 (98.42%), Query Frame = 3 Query: 63 MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISRTLVE 632 MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPL++AEKGSHGRPIRIY+EGVFD+FHYGHANLFLQAKSYFPG+IWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSG VADIYEELKKQNRFIPSKRTEN STTQIIDAI RT+VE Sbjct: 1 MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPLHIAEKGSHGRPIRIYVEGVFDLFHYGHANLFLQAKSYFPGKIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGDVADIYEELKKQNRFIPSKRTENTSTTQIIDAIGRTVVE 190
BLAST of Choline-phosphate cytidylyltransferase vs. Planmine SMEST
Match: SMESG000055914.1 (SMESG000055914.1) HSP 1 Score: 385.571 bits (989), Expect = 6.163e-138 Identity = 181/190 (95.26%), Postives = 186/190 (97.89%), Query Frame = 3 Query: 63 MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISRTLVE 632 MTFNIENITN NSPLAYMSTDAEMGILRHQMGHFKPIPL++AEKGSHGRPIRIY+EGVFD+FHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSG VADIYEELKKQNRFIPSKRTEN STTQIIDAI RT+VE Sbjct: 1 MTFNIENITNLNSPLAYMSTDAEMGILRHQMGHFKPIPLHIAEKGSHGRPIRIYVEGVFDLFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGDVADIYEELKKQNRFIPSKRTENTSTTQIIDAIGRTVVE 190
BLAST of Choline-phosphate cytidylyltransferase vs. Planmine SMEST
Match: SMESG000055388.1 (SMESG000055388.1) HSP 1 Score: 375.555 bits (963), Expect = 4.587e-134 Identity = 180/190 (94.74%), Postives = 184/190 (96.84%), Query Frame = 3 Query: 63 MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISRTLVE 632 MTFNIENITNRNSPLAYMSTDAEMGILR+QMGHFKPIPLYVAEKGSH RPIRIYIEGVFDMFHYGHANLFLQAKSYFPG+I VVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDE+RIDFAM DPSPYPSG VADIYEELKKQNRFIPSKRTEN STTQII+AI RTLVE Sbjct: 1 MTFNIENITNRNSPLAYMSTDAEMGILRYQMGHFKPIPLYVAEKGSHDRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGKIRVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEYRIDFAMIDPSPYPSGDVADIYEELKKQNRFIPSKRTENTSTTQIINAIGRTLVE 190
BLAST of Choline-phosphate cytidylyltransferase vs. Planmine SMEST
Match: SMESG000081359.1 (SMESG000081359.1) HSP 1 Score: 273.478 bits (698), Expect = 1.261e-93 Identity = 123/187 (65.78%), Postives = 151/187 (80.75%), Query Frame = 3 Query: 63 MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAISRT 623 MTFN + I NS LA +STD E+ I+R ++ +F PIP +AEKG+ RPIRIY+EGV+D+FHYGHANL QAK+YFPG +WVVAGVS+E +C KYKRKPIM+++ER+LSVRHCRHVDEVI N PWITT+ FL+E+++DF MHD YPSG VAD+YEE K RFIPSKRTEN STT+IID I R+ Sbjct: 1 MTFNFDEIKYNNSCLAKLSTDNEVKIIREKLTNFSPIPFDIAEKGNQNRPIRIYVEGVYDLFHYGHANLLFQAKNYFPGPVWVVAGVSNEVECEKYKRKPIMRSDERVLSVRHCRHVDEVIENVPWITTISFLNENKLDFMMHDAKLYPSGDVADVYEEAKANGRFIPSKRTENTSTTEIIDHIIRS 187
BLAST of Choline-phosphate cytidylyltransferase vs. Planmine SMEST
Match: SMESG000017201.1 (SMESG000017201.1) HSP 1 Score: 100.523 bits (249), Expect = 1.208e-24 Identity = 48/139 (34.53%), Postives = 78/139 (56.12%), Query Frame = 3 Query: 198 SHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRKPIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 S +P+R++++G FDM H+GHAN QAK ++ GV + + + +K P+ EER ++ + VDEV+ NAP++T VE L+++ DF H D Y ++K ++F KRT ISTT ++D + Sbjct: 2 SENKPVRVWVDGCFDMLHFGHANALRQAKELGDA---LIVGVHSDDEILFHKGPPVFSEEERYKMIKSIKWVDEVVENAPYVTEVETLEKYNCDFCAHGDDITVGADGLDTYHKVKSADKFKEFKRTHGISTTDLVDRL 137 HSP 2 Score: 56.6102 bits (135), Expect = 3.639e-9 Identity = 49/170 (28.82%), Postives = 75/170 (44.12%), Query Frame = 3 Query: 126 AEMGILRHQMGH-FKPIPLYVAE-----KGSHGRPIRIYIEGVFDMFHYGHANLFLQAKSYFPGQIWVVAGVSDEKDCMKYKRK-PIMKTEERILSVRHCRHVDEVIPNAPWITTVEFLDEHRIDFAMHDPSPYPSGGVADIYEELKKQNRFIPSKRTENISTTQIIDAI 614 A M I + G F P L +A+ +G +Y+ G FD+FH GH +FL+ + Y G +V SDE Y K PIM ER+LSV C+ V V+ P+ T ++ ID +H + DI+E ++ +F ++ +I I Sbjct: 154 ATMKISSYTKGFGFLPSSLQIAQFQQFIRGPRAGEKVLYVPGSFDLFHVGHC-MFLE-ECYKLGTYVIVGVYSDETVKSIYGLKYPIMNLYERVLSVLSCKFVSNVVICPPYKITENMMEMLNIDLVVHGKTHCKDA--EDIFEVPRQLGQFSTVDSGSTLTFESLIQRI 319 The following BLAST results are available for this feature:
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 2
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 3
BLAST of Choline-phosphate cytidylyltransferase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Choline-phosphate cytidylyltransferase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035391 ID=SMED30035391|Name=Choline-phosphate cytidylyltransferase|organism=Schmidtea mediterranea sexual|type=transcript|length=736bpback to top protein sequence of SMED30035391-orf-1 >SMED30035391-orf-1 ID=SMED30035391-orf-1|Name=SMED30035391-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=191bp MTFNIENITNRNSPLAYMSTDAEMGILRHQMGHFKPIPLYVAEKGSHGRPback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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