LIM zinc-binding domain-containing protein

Overview
NameLIM zinc-binding domain-containing protein
Smed IDSMED30035383
Length (bp)1225
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of LIM zinc-binding domain-containing protein (SMED30035383) t-SNE clustered cells

Violin plots show distribution of expression levels for LIM zinc-binding domain-containing protein (SMED30035383) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of LIM zinc-binding domain-containing protein (SMED30035383) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for LIM zinc-binding domain-containing protein (SMED30035383) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035383

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 8

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30035383SMESG000001219.1 Contig1431GPL15192PMID:23079596
Forsthoefel et al., 2012		FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
protonephridiaSMED30035383SMESG000001219.1 dd_Smed_v4_4138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035383SMESG000001219.1 dd_Smed_v4_4138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035383SMESG000001219.1 dd_Smed_v4_4138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035383SMESG000001219.1 dd_Smed_v4_4138_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035383SMESG000043419.1 Contig1334GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035383SMESG000001219.1 Contig1334GPL15192PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
epidermisSMED30035383SMESG000001219.1 dd_Smed_v4_4138_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017		whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Human
Match: XIRP2 (xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303])

HSP 1 Score: 83.5741 bits (205), Expect = 1.913e-16
Identity = 34/89 (38.20%), Postives = 55/89 (61.80%), Query Frame = 3 
Query:  324 GNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
             +  +  +T ++ +   SDK  ++C++C+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct: 3279 ASATEMRTTFQEESAFISDK--EICILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDE 3365
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Human
Match: XIRP2 (xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303])

HSP 1 Score: 81.6481 bits (200), Expect = 5.953e-16
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C++C+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct:  408 EICILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDE 474
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Human
Match: XIRP2 (xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303])

HSP 1 Score: 81.6481 bits (200), Expect = 5.986e-16
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C++C+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct:  400 EICILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDE 466
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Human
Match: XIRP2 (xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303])

HSP 1 Score: 81.6481 bits (200), Expect = 6.123e-16
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C++C+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct:  433 EICILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDE 499
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Human
Match: XIRP2 (xin actin binding repeat containing 2 [Source:HGNC Symbol;Acc:HGNC:14303])

HSP 1 Score: 81.2629 bits (199), Expect = 6.499e-16
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C++C+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct:  178 EICILCQKTVYPMECLVADKQNFHKSCFRCHHCNSKLSLGNYASLHGQIYCKPHFKQLFKSKGNYDE 244
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Celegans
Match: ceh-14 (Homeobox protein ceh-14 [Source:UniProtKB/Swiss-Prot;Acc:P20271])

HSP 1 Score: 56.225 bits (134), Expect = 1.793e-8
Identity = 30/80 (37.50%), Postives = 41/80 (51.25%), Query Frame = 3 
Query:  336 DFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIR 575
            DFS+     N G  +    +C +C+ KI       V+GR YH  C RCS CK  L  T F L  +S+YC+ HF + F  +
Sbjct:   32 DFSNV----NAGHPNNEEAICSLCDKKIRDRFVSKVNGRCYHSSCLRCSTCKDELGATCF-LREDSMYCRAHFYKKFGTK 106
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Celegans
Match: tag-273 (pep chromosome:WBcel235:IV:14487086:14505166:-1 gene:WBGene00013289.1 transcript:Y57G11A.1f.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-273)

HSP 1 Score: 53.9138 bits (128), Expect = 1.784e-7
Identity = 22/57 (38.60%), Postives = 29/57 (50.88%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNS--IYCKIHF 554
            D C +C   +Y  E+    G LYH  CFRC  CK  L V   +    S  +YC++HF
Sbjct:  791 DKCSLCTKNVYRAEQFQCFGLLYHVNCFRCIDCKQALRVEKAHRCQQSGDLYCRVHF 847

HSP 2 Score: 49.6766 bits (117), Expect = 3.382e-6
Identity = 25/57 (43.86%), Postives = 36/57 (63.16%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELF 566
            C IC+  +YP+EK+  +  LYH  CF+C KC   L+ TNFN     + CK+H +E+F
Sbjct:  192 CCICDKVVYPVEKVLANKNLYHIQCFKCCKCAKKLTPTNFNSHEGKLLCKVHMLEVF 248
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Celegans
Match: tag-273 (pep chromosome:WBcel235:IV:14487086:14505139:-1 gene:WBGene00013289.1 transcript:Y57G11A.1e.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-273)

HSP 1 Score: 53.5286 bits (127), Expect = 1.836e-7
Identity = 22/57 (38.60%), Postives = 29/57 (50.88%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNS--IYCKIHF 554
            D C +C   +Y  E+    G LYH  CFRC  CK  L V   +    S  +YC++HF
Sbjct:  799 DKCSLCTKNVYRAEQFQCFGLLYHVNCFRCIDCKQALRVEKAHRCQQSGDLYCRVHF 855

HSP 2 Score: 49.6766 bits (117), Expect = 3.419e-6
Identity = 25/57 (43.86%), Postives = 36/57 (63.16%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELF 566
            C IC+  +YP+EK+  +  LYH  CF+C KC   L+ TNFN     + CK+H +E+F
Sbjct:  200 CCICDKVVYPVEKVLANKNLYHIQCFKCCKCAKKLTPTNFNSHEGKLLCKVHMLEVF 256
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Celegans
Match: tag-273 (pep chromosome:WBcel235:IV:14487086:14496659:-1 gene:WBGene00013289.1 transcript:Y57G11A.1a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-273)

HSP 1 Score: 53.1434 bits (126), Expect = 2.123e-7
Identity = 22/57 (38.60%), Postives = 29/57 (50.88%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNS--IYCKIHF 554
            D C +C   +Y  E+    G LYH  CFRC  CK  L V   +    S  +YC++HF
Sbjct:  506 DKCSLCTKNVYRAEQFQCFGLLYHVNCFRCIDCKQALRVEKAHRCQQSGDLYCRVHF 562
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Celegans
Match: tag-273 (pep chromosome:WBcel235:IV:14487086:14489778:-1 gene:WBGene00013289.1 transcript:Y57G11A.1c.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:tag-273)

HSP 1 Score: 48.521 bits (114), Expect = 6.803e-7
Identity = 22/57 (38.60%), Postives = 29/57 (50.88%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNS--IYCKIHF 554
            D C +C   +Y  E+    G LYH  CFRC  CK  L V   +    S  +YC++HF
Sbjct:   37 DKCSLCTKNVYRAEQFQCFGLLYHVNCFRCIDCKQALRVEKAHRCQQSGDLYCRVHF 93
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Fly
Match: CG33521 (gene:FBgn0250819 transcript:FBtr0091473)

HSP 1 Score: 56.6102 bits (135), Expect = 2.741e-8
Identity = 31/140 (22.14%), Postives = 63/140 (45.00%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGR----LYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKS--------------LLEKFRQLESGSVSYQSSLSKNSNNTVRYVK 761
            C  C+  +Y ME++ +  +    ++HK C RC  C   L   ++N+ + S+YC +HF  +F  +  Y++      E++ +  +P +  P     S              L  KF+  E+G   + ++L +  +  + + K
Sbjct:   66 CHQCKKPVYKMEEVILSLKTATTIFHKTCLRCKDCGKHLKFDSYNVHDGSLYCSMHFKLIFAPKVVYEEFTPRKAELIIRENQPIKLPPDVAKASDKPSLGLDELQELNLRSKFKVFENGYEEHNNNLRERQDIAITHSK 205
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Fly
Match: CG33521 (gene:FBgn0250819 transcript:FBtr0091470)

HSP 1 Score: 56.6102 bits (135), Expect = 2.741e-8
Identity = 31/140 (22.14%), Postives = 63/140 (45.00%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGR----LYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKS--------------LLEKFRQLESGSVSYQSSLSKNSNNTVRYVK 761
            C  C+  +Y ME++ +  +    ++HK C RC  C   L   ++N+ + S+YC +HF  +F  +  Y++      E++ +  +P +  P     S              L  KF+  E+G   + ++L +  +  + + K
Sbjct:   66 CHQCKKPVYKMEEVILSLKTATTIFHKTCLRCKDCGKHLKFDSYNVHDGSLYCSMHFKLIFAPKVVYEEFTPRKAELIIRENQPIKLPPDVAKASDKPSLGLDELQELNLRSKFKVFENGYEEHNNNLRERQDIAITHSK 205
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Fly
Match: CG33521 (gene:FBgn0250819 transcript:FBtr0091472)

HSP 1 Score: 56.225 bits (134), Expect = 2.942e-8
Identity = 31/140 (22.14%), Postives = 63/140 (45.00%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGR----LYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKS--------------LLEKFRQLESGSVSYQSSLSKNSNNTVRYVK 761
            C  C+  +Y ME++ +  +    ++HK C RC  C   L   ++N+ + S+YC +HF  +F  +  Y++      E++ +  +P +  P     S              L  KF+  E+G   + ++L +  +  + + K
Sbjct:   80 CHQCKKPVYKMEEVILSLKTATTIFHKTCLRCKDCGKHLKFDSYNVHDGSLYCSMHFKLIFAPKVVYEEFTPRKAELIIRENQPIKLPPDVAKASDKPSLGLDELQELNLRSKFKVFENGYEEHNNNLRERQDIAITHSK 219
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Fly
Match: CG33521 (gene:FBgn0250819 transcript:FBtr0334661)

HSP 1 Score: 55.8398 bits (133), Expect = 3.739e-8
Identity = 31/140 (22.14%), Postives = 63/140 (45.00%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGR----LYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKS--------------LLEKFRQLESGSVSYQSSLSKNSNNTVRYVK 761
            C  C+  +Y ME++ +  +    ++HK C RC  C   L   ++N+ + S+YC +HF  +F  +  Y++      E++ +  +P +  P     S              L  KF+  E+G   + ++L +  +  + + K
Sbjct:   80 CHQCKKPVYKMEEVILSLKTATTIFHKTCLRCKDCGKHLKFDSYNVHDGSLYCSMHFKLIFAPKVVYEEFTPRKAELIIRENQPIKLPPDVAKASDKPSLGLDELQELNLRSKFKVFENGYEEHNNNLRERQDIAITHSK 219
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Fly
Match: Lasp (gene:FBgn0063485 transcript:FBtr0100145)

HSP 1 Score: 50.447 bits (119), Expect = 2.005e-6
Identity = 17/53 (32.08%), Postives = 30/53 (56.60%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHF 554
            C  C+  +YP+E+L    + +HK CF+C++C   L++  +   N   YC+ H 
Sbjct:    5 CARCQKVVYPIEELKCLDKTWHKTCFKCTECGMTLNMKTYKGYNKMPYCEAHI 57
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Zebrafish
Match: lima1a (LIM domain and actin binding 1a [Source:ZFIN;Acc:ZDB-GENE-001120-1])

HSP 1 Score: 81.6481 bits (200), Expect = 3.030e-16
Identity = 29/65 (44.62%), Postives = 45/65 (69.23%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            C+ C   +YP+EKL  + ++YH  CFRC+ C T LS+ N+   +N++YCK H+ +LFK +G YD+
Sbjct:  246 CVTCLKTVYPLEKLVANQQIYHNTCFRCAYCNTKLSLVNYASLHNNVYCKPHYCQLFKAKGNYDE 310
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Zebrafish
Match: xirp2a (xin actin binding repeat containing 2a [Source:ZFIN;Acc:ZDB-GENE-040108-7])

HSP 1 Score: 80.8777 bits (198), Expect = 5.576e-16
Identity = 28/67 (41.79%), Postives = 44/67 (65.67%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            +LC +C  ++YPME L  D + +HK CFRC+ C + LS+  +   +  +YCK H+ +LFK +G YD+
Sbjct:  264 ELCQVCRKRVYPMESLIADKQNFHKTCFRCAHCNSQLSLGTYASLHGRMYCKPHYKQLFKSKGNYDE 330
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Zebrafish
Match: xirp2b (xin actin binding repeat containing 2b [Source:ZFIN;Acc:ZDB-GENE-030521-26])

HSP 1 Score: 73.9442 bits (180), Expect = 1.483e-14
Identity = 27/67 (40.30%), Postives = 43/67 (64.18%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C +C+ ++YPME L  D + +HK CF C  CK  LS+ NF   +  +YC+ H+ +LFK +G  +D
Sbjct:  135 EMCAVCKKRVYPMEGLIADKKKFHKSCFFCEHCKNKLSLGNFVSLHGHLYCQPHYKQLFKSKGNLED 201
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Zebrafish
Match: limd2 (LIM domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-120906-1])

HSP 1 Score: 68.9366 bits (167), Expect = 6.007e-14
Identity = 27/65 (41.54%), Postives = 38/65 (58.46%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            C  CE  +YPME+L  +  ++H  CF C  C T LS+ ++       YCK HF +LFK +G YD+
Sbjct:   27 CASCEKTVYPMERLVANNLIFHAACFCCKHCNTKLSLGSYAALQGEFYCKPHFQQLFKSKGNYDE 91
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Zebrafish
Match: mical3a (microtubule associated monooxygenase, calponin and LIM domain containing 3a [Source:NCBI gene;Acc:402881])

HSP 1 Score: 66.6254 bits (161), Expect = 3.092e-11
Identity = 23/66 (34.85%), Postives = 41/66 (62.12%), Query Frame = 3 
Query:  363 NLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTN--FNLSNNSIYCKIHF 554
            N+G SD    +C  C  ++Y ME+L+ +G+ +H+ CF+C  C T L +++  F++ +   YCK H+
Sbjct:  767 NIGGSD----VCFFCRKRVYVMERLSAEGKFFHRSCFKCDYCGTTLRLSSYAFDVEDGKFYCKPHY 828
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000049904.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:9:64558417:64561350:-1 gene:ENSXETG00000020789.1 transcript:ENSXETT00000049904.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 6.217e-18
Identity = 37/90 (41.11%), Postives = 52/90 (57.78%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTD 659
            D C+IC+ K+YPME L  D +++H  CFRCS C   LS+ N+   +  IYCK HF +LFK +G YD+    G +   +   P    P T+
Sbjct:    8 DTCIICQKKVYPMECLVADKQIFHNSCFRCSHCSNKLSLGNYASLHGQIYCKAHFKQLFKSKGNYDE--GFGYKQHKELWHPKNQTPDTN 95
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Xenopus
Match: lima1 (LIM domain and actin binding 1 [Source:NCBI gene;Acc:779798])

HSP 1 Score: 87.0409 bits (214), Expect = 9.565e-18
Identity = 31/67 (46.27%), Postives = 46/67 (68.66%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C  C+  +YPME+L  + ++YH GCFRCS C T LS+  F   + ++YCK HF +LFK +G YD+
Sbjct:  354 EVCFSCQKTVYPMERLFANNQVYHNGCFRCSHCSTKLSLGTFASLHGTVYCKPHFNQLFKSKGNYDE 420
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Xenopus
Match: limd2 (uncharacterized loc100145002 [Source:Xenbase;Acc:XB-GENE-5749128])

HSP 1 Score: 71.633 bits (174), Expect = 3.448e-14
Identity = 27/67 (40.30%), Postives = 39/67 (58.21%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            +LC  C+  +YPME+L  D  ++H  CF C  C   LS+  +   +   YCK HF +LFK +G YD+
Sbjct:   86 ELCSSCQKTVYPMERLVADKHIFHNSCFCCKHCSAKLSLGTYAALHGEFYCKPHFQQLFKSKGNYDE 152
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Xenopus
Match: nudt13 (nudix hydrolase 13 [Source:Xenbase;Acc:XB-GENE-987788])

HSP 1 Score: 66.6254 bits (161), Expect = 4.198e-11
Identity = 24/66 (36.36%), Postives = 40/66 (60.61%), Query Frame = 3 
Query:  363 NLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVT--NFNLSNNSIYCKIHF 554
            NLG SD    +C  C  ++Y ME+L+ +G+ +H+ CF+C  C T L ++   ++L +   YCK H+
Sbjct:  780 NLGGSD----VCYFCRRRVYVMERLSAEGKFFHRSCFKCDYCSTTLRLSCYAYDLEDGKFYCKPHY 841
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Xenopus
Match: nudt13 (nudix hydrolase 13 [Source:Xenbase;Acc:XB-GENE-987788])

HSP 1 Score: 66.6254 bits (161), Expect = 4.539e-11
Identity = 24/66 (36.36%), Postives = 40/66 (60.61%), Query Frame = 3 
Query:  363 NLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVT--NFNLSNNSIYCKIHF 554
            NLG SD    +C  C  ++Y ME+L+ +G+ +H+ CF+C  C T L ++   ++L +   YCK H+
Sbjct:  780 NLGGSD----VCYFCRRRVYVMERLSAEGKFFHRSCFKCDYCSTTLRLSCYAYDLEDGKFYCKPHY 841
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Mouse
Match: Xirp2 (xin actin-binding repeat containing 2 [Source:MGI Symbol;Acc:MGI:2685198])

HSP 1 Score: 87.4261 bits (215), Expect = 7.381e-18
Identity = 39/102 (38.24%), Postives = 60/102 (58.82%), Query Frame = 3 
Query:  285 EKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            E+ F     ET+  +  + S   ++ +   SDK  ++C+IC+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct: 3222 ERVFQRVGYETSDAHATEMSRAFQEESAFLSDK--EICIICQKTVYPMECLIADKQNFHKSCFRCHHCSSKLSLGNYASLHGRIYCKPHFKQLFKSKGNYDE 3321
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Mouse
Match: Xirp2 (xin actin-binding repeat containing 2 [Source:MGI Symbol;Acc:MGI:2685198])

HSP 1 Score: 81.6481 bits (200), Expect = 3.814e-16
Identity = 31/67 (46.27%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C+IC+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct:  172 EICIICQKTVYPMECLIADKQNFHKSCFRCHHCSSKLSLGNYASLHGRIYCKPHFKQLFKSKGNYDE 238
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Mouse
Match: Xirp2 (xin actin-binding repeat containing 2 [Source:MGI Symbol;Acc:MGI:2685198])

HSP 1 Score: 81.6481 bits (200), Expect = 4.169e-16
Identity = 31/67 (46.27%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C+IC+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct:  401 EICIICQKTVYPMECLIADKQNFHKSCFRCHHCSSKLSLGNYASLHGRIYCKPHFKQLFKSKGNYDE 467
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Mouse
Match: Lima1 (LIM domain and actin binding 1 [Source:MGI Symbol;Acc:MGI:1920992])

HSP 1 Score: 75.8702 bits (185), Expect = 2.708e-14
Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            C+ C+  +YPME+L  + +++H  CFRCS C   LS+  +   +  IYCK HF +LFK +G YD+
Sbjct:  388 CVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDE 452
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Mouse
Match: Lima1 (LIM domain and actin binding 1 [Source:MGI Symbol;Acc:MGI:1920992])

HSP 1 Score: 75.485 bits (184), Expect = 3.100e-14
Identity = 28/65 (43.08%), Postives = 42/65 (64.62%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            C+ C+  +YPME+L  + +++H  CFRCS C   LS+  +   +  IYCK HF +LFK +G YD+
Sbjct:  228 CVECQKTVYPMERLLANQQVFHISCFRCSYCNNKLSLGTYASLHGRIYCKPHFNQLFKSKGNYDE 292
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4U4S6|XIRP2_MOUSE (Xin actin-binding repeat-containing protein 2 OS=Mus musculus OX=10090 GN=Xirp2 PE=1 SV=1)

HSP 1 Score: 87.4261 bits (215), Expect = 5.163e-17
Identity = 39/102 (38.24%), Postives = 60/102 (58.82%), Query Frame = 3 
Query:  285 EKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            E+ F     ET+  +  + S   ++ +   SDK  ++C+IC+  +YPME L  D + +HK CFRC  C + LS+ N+   +  IYCK HF +LFK +G YD+
Sbjct: 3222 ERVFQRVGYETSDAHATEMSRAFQEESAFLSDK--EICIICQKTVYPMECLIADKQNFHKSCFRCHHCSSKLSLGNYASLHGRIYCKPHFKQLFKSKGNYDE 3321
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. UniProt/SwissProt
Match: sp|O80839|PLI2A_ARATH (LIM domain-containing protein PLIM2a OS=Arabidopsis thaliana OX=3702 GN=PLIM2A PE=1 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 1.952e-14
Identity = 35/93 (37.63%), Postives = 53/93 (56.99%), Query Frame = 3 
Query:  387 LDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTK 665
            LD C  C+  +Y M+ LT++G  YHK CFRC+ CK  L ++N++  +  +YCK HF +LFK  G Y      G     + E+P + +  T +K
Sbjct:    7 LDKCKACDKTVYVMDLLTLEGNTYHKSCFRCTHCKGTLVISNYSSMDGVLYCKPHFEQLFKESGNYSKNFQAG-----KTEKPNDHLTRTPSK 94

HSP 2 Score: 69.3218 bits (168), Expect = 2.667e-12
Identity = 28/68 (41.18%), Postives = 44/68 (64.71%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDV 593
            D C  C+  +YP+EK+T++G  YHK CFRC+     L+ +++   N  +YCK+HF +LF  +G Y+ V
Sbjct:  104 DKCATCKKTVYPLEKVTMEGESYHKTCFRCTHSGCPLTHSSYASLNGVLYCKVHFNQLFLEKGSYNHV 171
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7F9R9|PLI2B_ORYSJ (LIM domain-containing protein PLIM2b OS=Oryza sativa subsp. japonica OX=39947 GN=PLIM2B PE=1 SV=1)

HSP 1 Score: 74.3294 bits (181), Expect = 4.178e-14
Identity = 30/68 (44.12%), Postives = 45/68 (66.18%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDV 593
            D C  C+  +YP+EKLT++G  YHK CF+CS    IL+ +++   N  +YCKIHF +LF  +G Y+ +
Sbjct:  103 DKCAACQKTVYPLEKLTLEGESYHKSCFKCSHGGCILTTSSYAALNGVLYCKIHFGQLFMEKGSYNHM 170

HSP 2 Score: 66.2402 bits (160), Expect = 2.531e-11
Identity = 29/72 (40.28%), Postives = 44/72 (61.11%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIG 605
            D C  C+  ++ ++ LT DG  YHK CF+CS CK ILS+ +++  +  +YCK HF +LFK  G +    + G
Sbjct:    8 DKCTACDKTVHFIDLLTADGVPYHKTCFKCSHCKGILSMCSYSSMDGVLYCKTHFEQLFKETGSFSKKFAPG 79
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9BT23|LIMD2_HUMAN (LIM domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LIMD2 PE=1 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 7.284e-14
Identity = 32/84 (38.10%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  342 SSTIKDSNLGSSDKNL-DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            SST++ S   S    + + C  C+  +YPME+L  D  ++H  CF C  C T LS+ ++   +   YCK HF +LFK +G YD+
Sbjct:   21 SSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPHFQQLFKSKGNYDE 104
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. UniProt/SwissProt
Match: sp|Q1LZA7|LIMD2_BOVIN (LIM domain-containing protein 2 OS=Bos taurus OX=9913 GN=LIMD2 PE=2 SV=1)

HSP 1 Score: 71.2478 bits (173), Expect = 8.820e-14
Identity = 32/84 (38.10%), Postives = 48/84 (57.14%), Query Frame = 3 
Query:  342 SSTIKDSNLGSSDKNL-DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            SST++ S   S    + + C  C+  +YPME+L  D  ++H  CF C  C T LS+ ++   +   YCK HF +LFK +G YD+
Sbjct:   22 SSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHSSCFCCKHCHTKLSLGSYAALHGEFYCKPHFQQLFKSKGNYDE 105
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. TrEMBL
Match: A0A267GIF7 (LIM zinc-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig025250g2 PE=4 SV=1)

HSP 1 Score: 121.324 bits (303), Expect = 4.066e-26
Identity = 80/262 (30.53%), Postives = 125/262 (47.71%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYD-DVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLES---------------GSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDI--QQEELPPPETAKAMVARFQAMESK---------------KNIPSPERVQQMQSQAKVNSTTNANIRFHNSSTQ------PNPIRDS-FNETEELPEEGTTRNLLNKFQN 1055
            D+C +C+ K+YPME+LT DG +YHK C+RC KC  +LSV NF + +N +YC+ H++E+F++RG Y         EIV ++       P  D  S ++K   L+S               GS  +    +  S N   +  P  DVVRS D    + ELPPP  +K+++A F+ +E+                K   +P + +  Q Q  ++    A +R    S        P+ +R    N  +ELP    TR+ L  ++N
Sbjct:  237 DVCRLCQKKVYPMEQLTSDGHVYHKSCYRCHKCNRLLSVGNFGVLDNQLYCQPHYLEIFRMRGHYQASADRPAAEIVGRDN------PVDDGISQVQKLSNLKSRFESSGDSSVVVTPPGSGGHHP--TPGSRNGA-HSDPPADVVRSGDAVPAEGELPPPGASKSVLAMFRNLETGGQQPAKDQQQQPGRLKGAVAPTQRRPYQPQPNMDFDYTAPVRSAAESESSPVERPPDVVRSGDPNPADELPPANFTRSALQMWKN 489
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. TrEMBL
Match: A0A267FBF0 (LIM zinc-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000523g2 PE=4 SV=1)

HSP 1 Score: 120.939 bits (302), Expect = 5.052e-26
Identity = 81/259 (31.27%), Postives = 126/259 (48.65%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYD-DVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLE-----SGS----VSYQSSLSKNSNNTVR---YVKPTDDVVRSQDI--QQEELPPPETAKAMVARFQAMESK---------------KNIPSPERVQQMQSQAKVNSTTNANIRFHNSSTQ------PNPIRDS-FNETEELPEEGTTRNLLNKFQN 1055
            D+C +C+ K+YPME+LT DG +YHK C+RC KC  +LSV NF + +N +YC+ H++E+F++RG Y         EIV ++       P  D  S ++K   L+     SG     V+  SS   +     R   +  P  DVVRS D    + ELPPP  +K+++A F+ +E+                K   +P + +  Q Q  ++    A +R    S        P+ +R    N  +ELP    TR+ L  ++N
Sbjct:  244 DVCRLCQKKVYPMEQLTSDGHVYHKSCYRCHKCNRLLSVGNFGVLDNQLYCQPHYLEIFRMRGHYQASADRPAAEIVGRDN------PVDDGISQVQKLSNLKSRFESSGDSSVVVTPPSSGGHHPTPGSRNGAHSDPPADVVRSGDAVPAEGELPPPGASKSVLAMFRNLETGGQQPAKDQQQQPGRLKGAVAPTQRRPYQPQPNMDFDYTAPVRSAAESESSPVERPPDVVRSGDPNPADELPPANFTRSALQMWKN 496
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. TrEMBL
Match: A0A267DW95 (LIM zinc-binding domain-containing protein (Fragment) OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig000523g7 PE=4 SV=1)

HSP 1 Score: 119.398 bits (298), Expect = 2.105e-25
Identity = 63/176 (35.80%), Postives = 96/176 (54.55%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYD-DVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLES---------------GSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDI--QQEELPPPETAKAMVARFQAMES 863
            D+C +C+ K+YPME+LT DG +YHK C+RC KC  +LSV NF + +N +YC+ H++E+F++RG Y         EIV ++       P  D  S ++K   L+S               GS  +    +  S N   +  P  DVVRS D    + ELPPP  +K+++A F+ +E+
Sbjct:  198 DVCRLCQKKVYPMEQLTSDGHVYHKSCYRCHKCNRLLSVGNFGVLDNQLYCQPHYLEIFRMRGHYQASADRPAAEIVGRDN------PVDDGISQVQKLSNLKSRFESSGDSSVVVTPPGSGGHHP--TPGSRNGA-HSDPPADVVRSGDAVPAEGELPPPGASKSVLAMFRNLET 364
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. TrEMBL
Match: A0A1I8J357 (LIM zinc-binding domain-containing protein OS=Macrostomum lignano OX=282301 PE=4 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 6.263e-21
Identity = 49/119 (41.18%), Postives = 71/119 (59.66%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYD-DVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLE-----SGSVSYQSSLS 728
            D+C +C+ K+YPME+LT DG +YHK C+RC KC  +LSV NF + +N +YC+ H++E+F++RG Y         EIV ++       P  D  S ++K   L+     SG  S QS LS
Sbjct:  280 DVCRLCQKKVYPMEQLTSDGHVYHKSCYRCHKCNRLLSVGNFGVLDNQLYCQPHYLEIFRMRGHYQASADRPAAEIVGRDN------PVDDGISQVQKLSNLKSRFESSGDSSQQSRLS 392
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. TrEMBL
Match: A0A267EUL3 (LIM zinc-binding domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig011398g1 PE=4 SV=1)

HSP 1 Score: 102.064 bits (253), Expect = 3.694e-20
Identity = 61/207 (29.47%), Postives = 100/207 (48.31%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIG---NEIVSQNEEPTET---------IPS-TDTKSLLEKFRQ-----------------LESGSVSYQSSLSK----NSNNTVRYVKPTDDVVRSQDIQQEELPP----------------PETAKAMVARFQAME 860
            D C +C  ++YPME+LT DG++YHK C+RC KCK  LSV NF + ++ +YC+ H++ELF+++G Y    S G   N I    +E  E          +P  ++ KS  E F +                 L+S    Y+++ S+    +S    R+  P +      + Q +ELPP                P +++ ++ARF+ +E
Sbjct:   17 DSCKMCHGRVYPMERLTSDGQVYHKSCYRCYKCKRQLSVGNFAIMDDRLYCQPHYIELFRLKGSYRFHDSAGVPVNSIAGSGDESVENGGGSNDSGHVPKLSNIKSRFESFEEQPPASPSKRKEKVYYAGLQSARHRYETATSEKERPHSEKPKRFTPPREGSAGVVESQPQELPPDVVRCYDNGDSDDRPAPGSSRNVLARFREIE 223
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Cavefish
Match: lima1a (LIM domain and actin binding 1a [Source:ZFIN;Acc:ZDB-GENE-001120-1])

HSP 1 Score: 83.9593 bits (206), Expect = 4.650e-17
Identity = 32/86 (37.21%), Postives = 53/86 (61.63%), Query Frame = 3 
Query:  348 TIKDSNLGSSDKNLDL-----CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++ D   G + K   L     C++C   +YP+E+L  + ++YH  CFRC+ C T LS+ N+   ++++YCK HF +LFK +G YD+
Sbjct:  292 SVPDQGAGKAFKKFRLPVRESCVMCLKTVYPLERLVANQQIYHNTCFRCAHCNTKLSLVNYASLHSTVYCKPHFCQLFKAKGNYDE 377
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000001570.2 (uncharacterized LOC103022480 [Source:NCBI gene;Acc:103022480])

HSP 1 Score: 74.3294 bits (181), Expect = 8.626e-14
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 3 
Query:  393 LCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            +C  CE+ +YPME++  D  + H  CF C  C+T LS+ N++      YC  H+ +LFK +G YD+
Sbjct:  321 MCYACETPVYPMERIVADEHVLHTSCFCCKHCRTKLSLHNYSSLYGEFYCVSHYQQLFKRKGNYDE 386
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000032509.1 (uncharacterized LOC103022480 [Source:NCBI gene;Acc:103022480])

HSP 1 Score: 73.559 bits (179), Expect = 1.364e-13
Identity = 26/66 (39.39%), Postives = 40/66 (60.61%), Query Frame = 3 
Query:  393 LCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            +C  CE+ +YPME++  D  + H  CF C  C+T LS+ N++      YC  H+ +LFK +G YD+
Sbjct:   90 MCYACETPVYPMERIVADEHVLHTSCFCCKHCRTKLSLHNYSSLYGEFYCVSHYQQLFKRKGNYDE 155
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Cavefish
Match: limd2 (LIM domain containing 2 [Source:NCBI gene;Acc:103034267])

HSP 1 Score: 63.5438 bits (153), Expect = 3.434e-12
Identity = 24/67 (35.82%), Postives = 37/67 (55.22%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            + C  C+  +YPME+L  +  ++H  CF C  C   LS+  +       YCK H+ +LFK +G YD+
Sbjct:   25 ETCAACQKTVYPMERLVANNLIFHTVCFCCKHCNAKLSLGTYAALQGEFYCKPHYQQLFKSKGNYDE 91
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Cavefish
Match: mical3a (microtubule associated monooxygenase, calponin and LIM domain containing 3a [Source:NCBI gene;Acc:402881])

HSP 1 Score: 66.2402 bits (160), Expect = 3.642e-11
Identity = 23/66 (34.85%), Postives = 41/66 (62.12%), Query Frame = 3 
Query:  363 NLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTN--FNLSNNSIYCKIHF 554
            N+G SD    +C  C  ++Y ME+L+ +G+ +H+ CF+C  C T L +++  F++ +   YCK H+
Sbjct:  736 NIGGSD----VCFFCRKRVYVMERLSAEGKFFHRSCFKCDYCGTTLRLSSYAFDVEDGKFYCKPHY 797
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Sea Lamprey
Match: mical3b (Danio rerio microtubule associated monooxygenase, calponin and LIM domain containing 3b (mical3b), mRNA. [Source:RefSeq mRNA;Acc:NM_001353875])

HSP 1 Score: 64.3142 bits (155), Expect = 2.729e-11
Identity = 24/66 (36.36%), Postives = 39/66 (59.09%), Query Frame = 3 
Query:  363 NLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVT--NFNLSNNSIYCKIHF 554
            NLG SD     C  C  ++Y ME+L+ +G+ +H+GCF+C+ C   L +    F++ +   YCK H+
Sbjct:  754 NLGGSDT----CYFCGRRVYVMERLSAEGKFFHRGCFKCNYCDVTLRLGAFAFDVEDGKFYCKPHY 815
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005882.1 (pep scaffold:Pmarinus_7.0:GL476535:329859:333216:1 gene:ENSPMAG00000005319.1 transcript:ENSPMAT00000005882.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 6.245e-10
Identity = 22/52 (42.31%), Postives = 31/52 (59.62%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIH 551
            C  C+  +YP+EKL   G+ +HK CF C +C+T+L+V NF       YC  H
Sbjct:    5 CARCQHPVYPLEKLDCLGQTWHKMCFYCEECETVLTVNNFKSFEKRPYCHAH 56
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Sea Lamprey
Match: csrp2 (cysteine and glycine-rich protein 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1863])

HSP 1 Score: 51.6026 bits (122), Expect = 4.399e-8
Identity = 25/73 (34.25%), Postives = 36/73 (49.32%), Query Frame = 3 
Query:  360 SNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRG 578
            S L  S    D C  C   +Y  EK+   G+ +H+ CFRC +C   L  T  N ++  IYCK  + + F  +G
Sbjct:  109 SPLARSFGGCDKCPRCSQSVYAAEKVMGAGKPWHRSCFRCKQCGKSLESTTLNDNDGEIYCKACYAKNFGPKG 181

HSP 2 Score: 44.669 bits (104), Expect = 9.439e-6
Identity = 19/61 (31.15%), Postives = 31/61 (50.82%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRG 578
            C  C   +Y  E++  DG+ YH+ CFRCS C+  L  T      + I+C+  + +    +G
Sbjct:   11 CGRCAKAVYQAEEVICDGQRYHRLCFRCSVCRKGLDSTTLATHGDEIFCRSCYGKKLGPKG 71
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Sea Lamprey
Match: csrp2 (cysteine and glycine-rich protein 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1863])

HSP 1 Score: 51.6026 bits (122), Expect = 4.999e-8
Identity = 25/73 (34.25%), Postives = 36/73 (49.32%), Query Frame = 3 
Query:  360 SNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRG 578
            S L  S    D C  C   +Y  EK+   G+ +H+ CFRC +C   L  T  N ++  IYCK  + + F  +G
Sbjct:  108 SPLARSFGGCDKCPRCSQSVYAAEKVMGAGKPWHRSCFRCKQCGKSLESTTLNDNDGEIYCKACYAKNFGPKG 180

HSP 2 Score: 47.3654 bits (111), Expect = 1.414e-6
Identity = 26/95 (27.37%), Postives = 43/95 (45.26%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRG-KYDDVISI-----GNEIVSQNEEPTETIPSTDT 662
            C  C   +Y  E++  DG+ YH+ CFRCS C+  L  T      + I+C+  + +    +G  Y     +     G  +  + EEP    P+ +T
Sbjct:   11 CGRCAKAVYQAEEVICDGQRYHRLCFRCSVCRKGLDSTTLATHGDEIFCRSCYGKKLGPKGYGYGQGAGVLSTDRGERLGIRPEEPGAPQPTFNT 105
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Sea Lamprey
Match: csrp2 (cysteine and glycine-rich protein 2 [Source:ZFIN;Acc:ZDB-GENE-040426-1863])

HSP 1 Score: 50.8322 bits (120), Expect = 8.515e-8
Identity = 22/63 (34.92%), Postives = 32/63 (50.79%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRG 578
            D C  C   +Y  EK+   G+ +HK CFRC+KC   L  T     +  +YCK  + + F  +G
Sbjct:  117 DACSRCTKPVYAAEKIVGAGKPWHKSCFRCAKCGKGLESTTVTDRDGELYCKGCYAKYFGPKG 179
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Nematostella
Match: EDO50008 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RF11])

HSP 1 Score: 75.0998 bits (183), Expect = 1.043e-16
Identity = 28/65 (43.08%), Postives = 43/65 (66.15%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            C +C   +YPME+L  D ++YHK CF+C++C   L + N+      +YCK HF +LFK++G YD+
Sbjct:   22 CEVCNKTVYPMERLAADKKVYHKFCFKCNECNNTLRLGNYAALQGKVYCKPHFKQLFKVKGNYDE 86
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Nematostella
Match: EDO25454 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWF5])

HSP 1 Score: 49.6766 bits (117), Expect = 2.082e-8
Identity = 20/51 (39.22%), Postives = 30/51 (58.82%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYC 542
            D C +C + +Y MEK   D  + H+ C +C  CK  L+V NF ++ + IYC
Sbjct:    1 DKCAVCGTTVYQMEKCKFDDCILHRQCMKCVVCKRHLTVGNFVMTESKIYC 51
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Nematostella
Match: EDO47999 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RKJ7])

HSP 1 Score: 55.8398 bits (133), Expect = 2.174e-8
Identity = 18/42 (42.86%), Postives = 27/42 (64.29%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNL 521
            CLIC  ++Y ME+L  + RL+H+ CFRCS+C + L    +  
Sbjct:  398 CLICGERVYLMERLVAERRLFHRACFRCSRCNSSLRAGTYTF 439
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Nematostella
Match: LASP1 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI30])

HSP 1 Score: 53.1434 bits (126), Expect = 3.258e-8
Identity = 18/53 (33.96%), Postives = 29/53 (54.72%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHF 554
            C  C   +YP+EKL+   +++HKGCF+C  C   L++  +       YC  H+
Sbjct:    5 CARCRKTVYPVEKLSCLDKVWHKGCFKCESCGMTLNMKTYKGYQKLPYCDAHY 57
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Nematostella
Match: LASP3 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI32])

HSP 1 Score: 50.447 bits (119), Expect = 2.963e-7
Identity = 19/53 (35.85%), Postives = 28/53 (52.83%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHF 554
            C  C   +Y  EKL    +++HK CFRC  C   L++ N+   N + YC  H+
Sbjct:    5 CTKCAKTVYSQEKLNCLDKIWHKTCFRCVVCNMALNMKNYKGYNKNPYCNAHY 57
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Medaka
Match: lima1a (LIM domain and actin-binding protein 1 [Source:NCBI gene;Acc:101156656])

HSP 1 Score: 87.0409 bits (214), Expect = 5.473e-18
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            + C+ C+  +YP+E+L  +  +YH  CFRCS C T LS+ N+   +N +YCK HF +LFK +G YD+
Sbjct:  292 ETCVTCQKTVYPLERLVANQHVYHSSCFRCSHCNTKLSLVNYASLHNVVYCKPHFCQLFKAKGNYDE 358
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Medaka
Match: lima1a (LIM domain and actin-binding protein 1 [Source:NCBI gene;Acc:101156656])

HSP 1 Score: 86.2705 bits (212), Expect = 7.947e-18
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            + C+ C+  +YP+E+L  +  +YH  CFRCS C T LS+ N+   +N +YCK HF +LFK +G YD+
Sbjct:  269 ETCVTCQKTVYPLERLVANQHVYHSSCFRCSHCNTKLSLVNYASLHNVVYCKPHFCQLFKAKGNYDE 335
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Medaka
Match: lima1a (LIM domain and actin-binding protein 1 [Source:NCBI gene;Acc:101156656])

HSP 1 Score: 85.8853 bits (211), Expect = 1.122e-17
Identity = 30/67 (44.78%), Postives = 45/67 (67.16%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            + C+ C+  +YP+E+L  +  +YH  CFRCS C T LS+ N+   +N +YCK HF +LFK +G YD+
Sbjct:  354 ETCVTCQKTVYPLERLVANQHVYHSSCFRCSHCNTKLSLVNYASLHNVVYCKPHFCQLFKAKGNYDE 420
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000019196.2 (LIM domain and actin-binding protein 1 [Source:NCBI gene;Acc:101163320])

HSP 1 Score: 76.2554 bits (186), Expect = 1.506e-14
Identity = 27/67 (40.30%), Postives = 44/67 (65.67%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C++C+  ++ +E+L     +YHK CFRC  C T LS+ N+   + + YCK HF +LFK +G YD+
Sbjct:  285 EVCVVCQKTVFQLERLMSHQHVYHKHCFRCFHCNTKLSLMNYASLHGNNYCKPHFSQLFKAKGNYDE 351
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Medaka
Match: limd2 (LIM domain containing 2 [Source:NCBI gene;Acc:101173786])

HSP 1 Score: 68.9366 bits (167), Expect = 4.350e-14
Identity = 27/67 (40.30%), Postives = 39/67 (58.21%), Query Frame = 3 
Query:  390 DLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDD 590
            ++C  CE  +YPME+L  + +++H  CF C  C   LS+  F       YCK HF +LFK +G YD+
Sbjct:   26 EVCTSCEKTVYPMERLVANDQVFHLSCFCCKHCNAKLSLGTFAALQGEFYCKPHFQQLFKSKGNYDE 92
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Planmine SMEST
Match: SMESG000001219.1 (SMESG000001219.1)

HSP 1 Score: 646.736 bits (1667), Expect = 0.000e+0
Identity = 315/316 (99.68%), Postives = 316/316 (100.00%), Query Frame = 3 
Query:  123 MEEFEYDPQYKSDDTEESNQANYEQPTENETSYVIQEICENTDVEITSLSHANPEKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLESGSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDIQQEELPPPETAKAMVARFQAMESKKNIPSPERVQQMQSQAKVNSTTNANIRFHNSSTQPNPIRDSFNETEELPEEGTTRNLLNKFQNLSNNA 1070
            MEEFEYDPQYKSDDTEESNQANYEQPTENETSYVIQEICENTDVEITSLSHANPEKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKT+LSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLESGSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDIQQEELPPPETAKAMVARFQAMESKKNIPSPERVQQMQSQAKVNSTTNANIRFHNSSTQPNPIRDSFNETEELPEEGTTRNLLNKFQNLSNNA
Sbjct:    1 MEEFEYDPQYKSDDTEESNQANYEQPTENETSYVIQEICENTDVEITSLSHANPEKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTVLSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLESGSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDIQQEELPPPETAKAMVARFQAMESKKNIPSPERVQQMQSQAKVNSTTNANIRFHNSSTQPNPIRDSFNETEELPEEGTTRNLLNKFQNLSNNA 316
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Planmine SMEST
Match: SMESG000044487.1 (SMESG000044487.1)

HSP 1 Score: 119.398 bits (298), Expect = 1.140e-29
Identity = 78/240 (32.50%), Postives = 122/240 (50.83%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDV-------ISIGNEIVSQNEEPTETIPSTD-TKSLLEKFRQLESGSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDIQQEELPPPETAKAMVARFQAMESKKNIPSPERVQQMQSQAKVNSTTNA--NIRFHNSSTQPN--------PIRDSFNETEELPEEGTTRNLLNKFQNLS 1061
            C +C  K+YPMEKL  + + +HK CFRCSKCK+ LS  N++ +    YC  H++ELFK RG+YD+V       I   N+I   N+  T+ +P+ D TK ++ KF+  E+G+    SS+++N+N            V S D    ELP P T K ++ +F A            +QQ  S+ K     +   +   H++ T  N         +R +    +  PE+G T+NL+N+F  + 
Sbjct:  203 CCVCNKKVYPMEKLVANDKTFHKTCFRCSKCKSALSTGNYSFNQQRPYCTPHYIELFKKRGRYDEVDDNVEKEIPATNDI---NDVLTDELPAPDTTKKIVAKFQNFETGNT---SSINQNAN------------VDSVD----ELPAPNTTKILMEKFSA------------IQQDNSEGKCKPQIDIPRHSNGHSNGTSENVPVVLPTDVVRANDPSQDNRPEQGITKNLVNRFHGMG 408
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Planmine SMEST
Match: SMESG000026096.1 (SMESG000026096.1)

HSP 1 Score: 102.834 bits (255), Expect = 1.567e-23
Identity = 68/224 (30.36%), Postives = 109/224 (48.66%), Query Frame = 3 
Query:  396 CLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQL-ESGSVSYQSSLSKNSNNTVRYVKPTDDVVRSQDIQQEELPPPETAKAMVARFQAMESKKNIPS--PERVQQMQSQAKVNSTTNANIRFHNSSTQPNPIRDSFNETEELPEEGTTRNLLNKFQNL 1058
            C  C  K+Y  EKL +D  LYH+ CF+C KC+ ILS+ NF  ++  +YCK HF+ELF+  GKY       NE   Q+ +        D+ S+   + ++ E+G+                          + + Q++ELPPP+  + +V +F+ +ES  +  S  P ++   Q   K   +TNA +  +N  T  +   D    T+E P  G T+NLL+ + N 
Sbjct:  205 CTSCGEKVYITEKLVIDNLLYHRQCFKCMKCRRILSMNNFASNSGRLYCKPHFLELFRQSGKY-------NEFHQQSNQ--------DSNSISTNYDKINENGTAG------------------------TGNTQEDELPPPQITRNIVEKFRLLESNLSADSLLPRQLSSGQHNVKCYQSTNA-VLDNNHHTYNDKADDV---TDEFPTPGITKNLLSLWSNF 385
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Planmine SMEST
Match: SMESG000040062.1 (SMESG000040062.1)

HSP 1 Score: 92.4337 bits (228), Expect = 1.521e-20
Identity = 53/148 (35.81%), Postives = 86/148 (58.11%), Query Frame = 3 
Query:  159 DDTEESNQANYEQPTENETSYVIQEI--C-ENTDVEITSLSHANPEKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKIRGKYDDV 593
            D++E+SN  N  Q  E +T +VI+EI  C +  D +   +  ++ E    +   +T+      F S +KD +   S      C +C+  +YPMEK+++D +LYHK CFRC  C+ +LS T      ++++CK H++E F+IRGKYDD+
Sbjct:   90 DESEKSNGGNITQEAE-QTPFVIKEIEKCPKQNDTDNFIVKQSDSEHQSQSKKTKTS------FQSKLKDQSNSDSK-----CDVCQKTVYPMEKVSMDSKLYHKNCFRCCVCQKMLSPTVVTKFKDNLFCKPHYIEKFRIRGKYDDI 225
[Close]
BLAST of LIM zinc-binding domain-containing protein vs. Planmine SMEST
Match: SMESG000002154.1 (SMESG000002154.1)

HSP 1 Score: 55.4546 bits (132), Expect = 1.038e-8
Identity = 20/54 (37.04%), Postives = 32/54 (59.26%), Query Frame = 3 
Query:  393 LCLICESKIYPMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHF 554
            LC  C   +YP+EKL+   + +HK CF+C++C   L++ N+   N   YC  H+
Sbjct:    4 LCGRCNKTVYPVEKLSCLDKYWHKMCFKCTQCDLTLTMKNYKGYNKMPYCSTHY 57
The following BLAST results are available for this feature:
BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
XIRP21.913e-1638.20xin actin binding repeat containing 2 [Source:HGNC... [more]
XIRP25.953e-1644.78xin actin binding repeat containing 2 [Source:HGNC... [more]
XIRP25.986e-1644.78xin actin binding repeat containing 2 [Source:HGNC... [more]
XIRP26.123e-1644.78xin actin binding repeat containing 2 [Source:HGNC... [more]
XIRP26.499e-1644.78xin actin binding repeat containing 2 [Source:HGNC... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ceh-141.793e-837.50Homeobox protein ceh-14 [Source:UniProtKB/Swiss-P... [more]
tag-2731.784e-738.60pep chromosome:WBcel235:IV:14487086:14505166:-1 ge... [more]
tag-2731.836e-738.60pep chromosome:WBcel235:IV:14487086:14505139:-1 ge... [more]
tag-2732.123e-738.60pep chromosome:WBcel235:IV:14487086:14496659:-1 ge... [more]
tag-2736.803e-738.60pep chromosome:WBcel235:IV:14487086:14489778:-1 ge... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CG335212.741e-822.14gene:FBgn0250819 transcript:FBtr0091473[more]
CG335212.741e-822.14gene:FBgn0250819 transcript:FBtr0091470[more]
CG335212.942e-822.14gene:FBgn0250819 transcript:FBtr0091472[more]
CG335213.739e-822.14gene:FBgn0250819 transcript:FBtr0334661[more]
Lasp2.005e-632.08gene:FBgn0063485 transcript:FBtr0100145[more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lima1a3.030e-1644.62LIM domain and actin binding 1a [Source:ZFIN;Acc:Z... [more]
xirp2a5.576e-1641.79xin actin binding repeat containing 2a [Source:ZFI... [more]
xirp2b1.483e-1440.30xin actin binding repeat containing 2b [Source:ZFI... [more]
limd26.007e-1441.54LIM domain containing 2 [Source:ZFIN;Acc:ZDB-GENE-... [more]
mical3a3.092e-1134.85microtubule associated monooxygenase, calponin and... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSXETT00000049904.16.217e-1841.11pep primary_assembly:Xenopus_tropicalis_v9.1:9:645... [more]
lima19.565e-1846.27LIM domain and actin binding 1 [Source:NCBI gene;A... [more]
limd23.448e-1440.30uncharacterized loc100145002 [Source:Xenbase;Acc:X... [more]
nudt134.198e-1136.36nudix hydrolase 13 [Source:Xenbase;Acc:XB-GENE-987... [more]
nudt134.539e-1136.36nudix hydrolase 13 [Source:Xenbase;Acc:XB-GENE-987... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Xirp27.381e-1838.24xin actin-binding repeat containing 2 [Source:MGI ... [more]
Xirp23.814e-1646.27xin actin-binding repeat containing 2 [Source:MGI ... [more]
Xirp24.169e-1646.27xin actin-binding repeat containing 2 [Source:MGI ... [more]
Lima12.708e-1443.08LIM domain and actin binding 1 [Source:MGI Symbol;... [more]
Lima13.100e-1443.08LIM domain and actin binding 1 [Source:MGI Symbol;... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q4U4S6|XIRP2_MOUSE5.163e-1738.24Xin actin-binding repeat-containing protein 2 OS=M... [more]
sp|O80839|PLI2A_ARATH1.952e-1437.63LIM domain-containing protein PLIM2a OS=Arabidopsi... [more]
sp|Q7F9R9|PLI2B_ORYSJ4.178e-1444.12LIM domain-containing protein PLIM2b OS=Oryza sati... [more]
sp|Q9BT23|LIMD2_HUMAN7.284e-1438.10LIM domain-containing protein 2 OS=Homo sapiens OX... [more]
sp|Q1LZA7|LIMD2_BOVIN8.820e-1438.10LIM domain-containing protein 2 OS=Bos taurus OX=9... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A267GIF74.066e-2630.53LIM zinc-binding domain-containing protein (Fragme... [more]
A0A267FBF05.052e-2631.27LIM zinc-binding domain-containing protein (Fragme... [more]
A0A267DW952.105e-2535.80LIM zinc-binding domain-containing protein (Fragme... [more]
A0A1I8J3576.263e-2141.18LIM zinc-binding domain-containing protein OS=Macr... [more]
A0A267EUL33.694e-2029.47LIM zinc-binding domain-containing protein OS=Macr... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lima1a4.650e-1737.21LIM domain and actin binding 1a [Source:ZFIN;Acc:Z... [more]
ENSAMXT00000001570.28.626e-1439.39uncharacterized LOC103022480 [Source:NCBI gene;Acc... [more]
ENSAMXT00000032509.11.364e-1339.39uncharacterized LOC103022480 [Source:NCBI gene;Acc... [more]
limd23.434e-1235.82LIM domain containing 2 [Source:NCBI gene;Acc:1030... [more]
mical3a3.642e-1134.85microtubule associated monooxygenase, calponin and... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mical3b2.729e-1136.36Danio rerio microtubule associated monooxygenase, ... [more]
ENSPMAT00000005882.16.245e-1042.31pep scaffold:Pmarinus_7.0:GL476535:329859:333216:1... [more]
csrp24.399e-834.25cysteine and glycine-rich protein 2 [Source:ZFIN;A... [more]
csrp24.999e-834.25cysteine and glycine-rich protein 2 [Source:ZFIN;A... [more]
csrp28.515e-834.92cysteine and glycine-rich protein 2 [Source:ZFIN;A... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO500081.043e-1643.08Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO254542.082e-839.22Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
EDO479992.174e-842.86Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
LASP13.258e-833.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
LASP32.963e-735.85Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
lima1a5.473e-1844.78LIM domain and actin-binding protein 1 [Source:NCB... [more]
lima1a7.947e-1844.78LIM domain and actin-binding protein 1 [Source:NCB... [more]
lima1a1.122e-1744.78LIM domain and actin-binding protein 1 [Source:NCB... [more]
ENSORLT00000019196.21.506e-1440.30LIM domain and actin-binding protein 1 [Source:NCB... [more]
limd24.350e-1440.30LIM domain containing 2 [Source:NCBI gene;Acc:1011... [more]
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BLAST of LIM zinc-binding domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000001219.10.000e+099.68SMESG000001219.1[more]
SMESG000044487.11.140e-2932.50SMESG000044487.1[more]
SMESG000026096.11.567e-2330.36SMESG000026096.1[more]
SMESG000040062.11.521e-2035.81SMESG000040062.1[more]
SMESG000002154.11.038e-837.04SMESG000002154.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035383 ID=SMED30035383|Name=LIM zinc-binding domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1225bp
GCGTTTGTTTATATCTATCAGAAATAATTTATATCTTCACACGGAGGACA
TTATTTATATTACCAGTGATATACCTTATATTTTAATAACGTTTAGACTG
TATTTAGAACTTGTTGACCGCTATGGAAGAATTTGAATATGATCCTCAAT
ATAAATCTGATGATACCGAAGAAAGTAATCAAGCTAACTATGAACAGCCA
ACTGAGAACGAAACTTCTTACGTTATTCAAGAAATATGTGAGAATACAGA
TGTCGAAATAACATCATTAAGTCATGCAAATCCTGAAAAAAATTTCAACA
ATGATTATATTGAGACAAATGTTGGAAACGTGGTTGATTTTAGTTCTACA
ATAAAGGACTCGAACTTAGGTTCAAGTGATAAAAATTTGGACTTATGTTT
GATTTGTGAGTCTAAAATTTATCCGATGGAAAAGTTGACAGTTGACGGAC
GGTTGTATCACAAGGGTTGTTTTCGATGCTCAAAATGCAAAACCATTTTA
TCAGTTACAAATTTCAATCTTAGCAACAATTCTATTTATTGTAAAATACA
TTTTATGGAGTTATTCAAAATTAGAGGTAAATATGATGACGTCATATCAA
TCGGAAATGAAATAGTATCACAAAATGAAGAACCAACGGAAACAATTCCT
TCTACTGATACGAAAAGCTTATTAGAAAAATTTCGTCAATTAGAATCCGG
GTCTGTGTCATATCAAAGCTCACTTTCAAAAAATTCAAATAACACAGTGA
GATATGTTAAACCGACAGATGATGTAGTCAGAAGTCAGGATATTCAACAG
GAGGAATTGCCACCCCCTGAAACTGCAAAAGCCATGGTTGCTAGATTTCA
AGCAATGGAGTCCAAGAAGAATATACCTTCTCCAGAACGTGTTCAGCAAA
TGCAATCGCAAGCTAAAGTTAATTCAACTACAAACGCAAATATTCGATTT
CATAATAGTTCAACTCAACCGAATCCGATTCGTGATAGTTTTAACGAAAC
TGAAGAACTGCCCGAAGAAGGAACTACTCGAAATTTGCTCAACAAGTTTC
AAAATTTATCAAATAATGCATAATTGCGTTCTGATAATTAAATTTCTAAG
TGATTGATAAACTATTATTTTATAAATGAATTACGAAATAGGCTGATTTT
TTTATCCAGTACAAGTTGTGTTTTAATTATACTTTTATCGAGTATTTGTT
TTTTTATTAACTGTATTAATGTTTT
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protein sequence of SMED30035383-orf-1

>SMED30035383-orf-1 ID=SMED30035383-orf-1|Name=SMED30035383-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=317bp
MEEFEYDPQYKSDDTEESNQANYEQPTENETSYVIQEICENTDVEITSLS
HANPEKNFNNDYIETNVGNVVDFSSTIKDSNLGSSDKNLDLCLICESKIY
PMEKLTVDGRLYHKGCFRCSKCKTILSVTNFNLSNNSIYCKIHFMELFKI
RGKYDDVISIGNEIVSQNEEPTETIPSTDTKSLLEKFRQLESGSVSYQSS
LSKNSNNTVRYVKPTDDVVRSQDIQQEELPPPETAKAMVARFQAMESKKN
IPSPERVQQMQSQAKVNSTTNANIRFHNSSTQPNPIRDSFNETEELPEEG
TTRNLLNKFQNLSNNA*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0046872metal ion binding
GO:0008270zinc ion binding
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000070intestinal phagocyte
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR001781Znf_LIM
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001781Zinc finger, LIM-typeSMARTSM00132lim_4coord: 91..143
e-value: 2.8E-11
score: 53.5
IPR001781Zinc finger, LIM-typePFAMPF00412LIMcoord: 92..147
e-value: 5.0E-11
score: 42.6
IPR001781Zinc finger, LIM-typePROSITEPS00478LIM_DOMAIN_1coord: 92..126
IPR001781Zinc finger, LIM-typePROSITEPS50023LIM_DOMAIN_2coord: 90..150
score: 12.731
NoneNo IPR availableGENE3DG3DSA:2.10.110.10coord: 87..156
e-value: 3.5E-18
score: 67.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 272..289
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 272..303
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..29
NoneNo IPR availablePANTHERPTHR24206FAMILY NOT NAMEDcoord: 34..174
NoneNo IPR availablePANTHERPTHR24206:SF55coord: 34..174
NoneNo IPR availableCDDcd09358LIM_Mical_likecoord: 92..144
e-value: 3.66902E-26
score: 96.1837
NoneNo IPR availableSUPERFAMILYSSF57716Glucocorticoid receptor-like (DNA-binding domain)coord: 88..117
NoneNo IPR availableSUPERFAMILYSSF57716Glucocorticoid receptor-like (DNA-binding domain)coord: 118..157