PKS_AT domain-containing protein

Overview
NamePKS_AT domain-containing protein
Smed IDSMED30035351
Length (bp)1266
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of PKS_AT domain-containing protein (SMED30035351) t-SNE clustered cells

Violin plots show distribution of expression levels for PKS_AT domain-containing protein (SMED30035351) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of PKS_AT domain-containing protein (SMED30035351) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for PKS_AT domain-containing protein (SMED30035351) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035351

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30035351SMESG000054688.1 SmedASXL_006930SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
X2 cellSMED30035351SMESG000054688.1 SmedASXL_006930SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
neoblastSMED30035351SMESG000054688.1 dd_Smed_v4_10612_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Human
Match: MCAT (malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622])

HSP 1 Score: 262.307 bits (669), Expect = 1.764e-83
Identity = 131/319 (41.07%), Postives = 201/319 (63.01%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
            + LFPGQG Q+VGM + L+N P+V+ L+ +A  +L YDLL+L + G    L++T++CQPAI+VAS+AA+EK+   QP +IENC+AAAG+S+GE  +LVFAGA+ F       +GL+ +++RA+ MQ A      G+L V   P+S+ N A   A+++C+  L + +P+C+++ +LF +C+VI GH EAL F++  + +F+   T+ L VSGAFHTRLM  AV P   AL+ +D I +  ++V+SN     +     I +LL +Q+   V+WEQ +  +Y R      P T E+GP  QL   +   N  A+K Y  +  
Sbjct:   64 VLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFA------EGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCK-SLGIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVD-IKKPLVSVYSNVHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKSCNMQAWKSYSAVDV 374
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Human
Match: MCAT (malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622])

HSP 1 Score: 132.494 bits (332), Expect = 3.656e-36
Identity = 57/105 (54.29%), Postives = 82/105 (78.10%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISF 549
            + LFPGQG Q+VGM + L+N P+V+ L+ +A  +L YDLL+L + G    L++T++CQPAI+VAS+AA+EK+   QP +IENC+AAAG+S+GE  +LVFAGA+ F
Sbjct:   64 VLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEF 168
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Human
Match: MCAT (malonyl-CoA-acyl carrier protein transacylase [Source:HGNC Symbol;Acc:HGNC:29622])

HSP 1 Score: 57.3806 bits (137), Expect = 4.889e-10
Identity = 27/48 (56.25%), Postives = 36/48 (75.00%), Query Frame = 1 
Query:  430 MAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISF-EGVAFSF 570
            +AA+EK+   QP +IENC+AAAG+S+GE  +LVFAGA+ F EG   S 
Sbjct:    1 LAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFAEGTGRSL 48
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Celegans
Match: C50D2.9 (pep chromosome:WBcel235:II:88221:91519:-1 gene:WBGene00016812.1 transcript:C50D2.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:C50D2.9)

HSP 1 Score: 217.624 bits (553), Expect = 2.043e-66
Identity = 121/346 (34.97%), Postives = 192/346 (55.49%), Query Frame = 1 
Query:  154 GEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTS-QSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIS 1188
            G ID+SQ         LP         + LFPGQG Q VGM + +++IP  +R+FD AS +L YD+LK+C +G   KL QT+YCQPAI  +S+AA E +K   P + EN    AG+S+GE  SLV    +SF         +  ++ RA+ M       K G++ +R+   S+L++A+  A++   E  +++  +C++A +L+   +VIGG    L ++E   +++N+ + KRL VS AFHTR M  AV     A + ++ I++   NV+SN +G + +S + +++  + KQI   V+WEQI   L+ +      P   E+G   QL   + +T+  A K Y H S
Sbjct:   81 GAIDFSQ---------LPIEEHV----VLLFPGQGAQFVGMGQKVMDIPAARRVFDEASEVLGYDMLKVCQDGPKQKLEQTLYCQPAIVTSSIAAFEALKASDPSIEENLTDTAGFSVGEYASLVAGKVLSFS------DAIKIVKTRAEAMSECAKLVKSGMVTIRVKAASKLDKAMADARKVAAENRELV--VCEVANYLYCGVRVIGGSETCLKYLEENQEKYNIQVMKRLAVSAAFHTRQMESAVEQVAKAFQNVE-IHRPVCNVWSNYSGKVMSSKKGDVRGAVAKQINSPVRWEQIQQSLFRKHQNEAFPRFYEVGAGRQLGAMLFQTSKKAHKNYSHFS 404
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BLAST of PKS_AT domain-containing protein vs. Ensembl Fly
Match: beg (gene:FBgn0036691 transcript:FBtr0075278)

HSP 1 Score: 258.07 bits (658), Expect = 3.346e-82
Identity = 134/310 (43.23%), Postives = 191/310 (61.61%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNA 1164
            + LFPGQG Q VGM K+L+  P  +R+F+ A+ +LKYDLLK+C+EG   KLN+T + Q A+ V+S+AALE+++ E+P+ IE C+AAAG+SLGEIT+LV+A A+ F+      + L  ++VRA  MQ AC+   G + +    P++ L EA   A+Q+C +K  +  P C IA +++  CKV+ G+ EAL+F+E  AK F +   KRL VSGAFHT LM+ AV P   AL+ +  +    I V+SN  G  +     I   L KQI   V+WEQ L  +Y R   ++ P T E GP   L   + K N  A
Sbjct:   69 VMLFPGQGTQYVGMAKDLLRFPGARRIFELANEVLKYDLLKICLEGPREKLNRTEHAQLAVMVSSLAALEQLREERPKAIETCVAAAGFSLGEITALVYADALPFD------KALRLVQVRATAMQAACDQAAGAMAMTLYGPDTNLGEACARAQQWCLDK-GVESPYCGIANYMYPHCKVVAGNVEALEFLEQNAKSFKIRRMKRLAVSGAFHTPLMQSAVEPFTKALKTVR-LQDPVIRVYSNVDGKPYRHAKHILTQLPKQIVRPVKWEQTLHEMYERKQGVDFPRTFECGPGKGLVQVLEKVNAKA 370
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Zebrafish
Match: mcat (malonyl CoA:ACP acyltransferase (mitochondrial) [Source:ZFIN;Acc:ZDB-GENE-041111-231])

HSP 1 Score: 259.61 bits (662), Expect = 5.891e-83
Identity = 131/323 (40.56%), Postives = 192/323 (59.44%), Query Frame = 1 
Query:  223 ASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
             +A I LFPGQG Q VGM + L+    V+ +F  A  +L YDLL LC+ G    L +T++CQPA++V S+AA+E++  E P  IE+C++A G+S+GE  +LVF+GA++F    F+      ++VRA+ MQ A +    G+L V   P++    A   A+++C   L + DP+C +A +LF + +VI GH EALDF++  +KE N   T+ L VSGAFHT LM  AV P R+ L +I+ + + +I+V SN  G  +     I+  L KQ+   V+WEQ L  +Y R    E P T E+GP   L   + K N  AFK Y H+  
Sbjct:   45 GNATILLFPGQGSQFVGMGRGLLKYGNVKEMFSVAQKVLGYDLLSLCLNGPEKDLMKTVHCQPAVFVCSLAAVERLNHENPAAIESCVSAVGFSVGEFAALVFSGAMNFAEALFA------VKVRAEAMQKASDQVSSGMLSVIGRPQAHYKHACVRAREHCVS-LGIQDPVCSVANYLFPDGRVIAGHKEALDFLQERSKELNFMRTRLLPVSGAFHTSLMEAAVEPLRDVLRKIE-VRRPEISVHSNVDGKRYMHDKHIRNQLAKQLVSPVKWEQTLHEIYQRAQGQEFPHTYEVGPGRHLGSMLQKCNMKAFKNYTHVDV 359
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Zebrafish
Match: mcat (malonyl CoA:ACP acyltransferase (mitochondrial) [Source:ZFIN;Acc:ZDB-GENE-041111-231])

HSP 1 Score: 169.088 bits (427), Expect = 1.265e-49
Identity = 90/228 (39.47%), Postives = 136/228 (59.65%), Query Frame = 1 
Query:  427 SMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVE 1110
            S+AA+E++  E P  IE+C++A G+S+GE  +LVF+GA++F    F+      ++VRA+ MQ A +    G+L V   P++    A   A+++C   L + DP+C +A +LF + +VI GH EALDF++  +KE N   T+ L VSGAFHT LM  AV P R+ L +I+ + + +I+V SN  G  +     I+  L KQ+   V+WEQ L  +Y R    E P T E
Sbjct:    2 SLAAVERLNHENPAAIESCVSAVGFSVGEFAALVFSGAMNFAEALFA------VKVRAEAMQKASDQVSSGMLSVIGRPQAHYKHACVRAREHCV-SLGIQDPVCSVANYLFPDGRVIAGHKEALDFLQERSKELNFMRTRLLPVSGAFHTSLMEAAVEPLRDVLRKIE-VRRPEISVHSNVDGKRYMHDKHIRNQLAKQLVSPVKWEQTLHEIYQRAQGQEFPHTYE 221
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Xenopus
Match: mcat (malonyl-CoA-acyl carrier protein transacylase [Source:NCBI gene;Acc:448008])

HSP 1 Score: 132.109 bits (331), Expect = 1.161e-35
Identity = 72/206 (34.95%), Postives = 114/206 (55.34%), Query Frame = 1 
Query:  574 GLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
             L+ ++VRA+ MQ A      G+L V   P+++ + A   A+++C+  L + DP+C++A  LF + +VI GH EAL +++S ++++ L  TK L VSGAFHT LM  A  P   AL+ +    Q  + V+ N  G  +   + I +LL KQ+   V+WEQ +  +Y R    + P T E GP  QL   + K N  A+  Y+ +  
Sbjct:    1 ALYAVKVRAEAMQEASELVPSGMLSVIGHPQTKYSVACAEAREHCRS-LGLEDPVCEVANFLFPDGRVIAGHIEALKYLQSNSRKYRLLRTKMLLVSGAFHTSLMEPAAAPLYKALKSLH-FKQPYVPVYCNVDGKRYKRAANIHQLLAKQVVSPVKWEQTMHAIYERKKGTDFPRTFEAGPGKQLGSILKKCNLKAWHSYRDVGV 204
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Mouse
Match: Mcat (malonyl CoA:ACP acyltransferase (mitochondrial) [Source:MGI Symbol;Acc:MGI:2388651])

HSP 1 Score: 261.151 bits (666), Expect = 3.097e-83
Identity = 130/319 (40.75%), Postives = 202/319 (63.32%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
            + LFPGQGCQ VGM   L+++P+V++L+++A  +L YDLL+LC+ G    L++T++CQPA++VAS+AA+EK+   QP +I+NC+AAAG+S+GE  +LVFAGA+ F       +GL+ ++ RA+ MQ A      G+L V    +S  + A   A+++C+  L + +P+CQ++ +LF +C+VI GH EAL F+   + +++   TK L VSG FHT LM  AV+P    L  I+ I +  + V SN +G  +T    I++LL +Q+   V+WEQ +  +Y R   +E P T E+GP  QL   +   N  A+K Y H+  
Sbjct:   62 VLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFS------EGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCK-SLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSIN-IKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDV 372
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Mouse
Match: Mcat (malonyl CoA:ACP acyltransferase (mitochondrial) [Source:MGI Symbol;Acc:MGI:2388651])

HSP 1 Score: 97.0561 bits (240), Expect = 6.611e-24
Identity = 39/77 (50.65%), Postives = 61/77 (79.22%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQP 465
            + LFPGQGCQ VGM   L+++P+V++L+++A  +L YDLL+LC+ G    L++T++CQPA++VAS+AA+EK+   QP
Sbjct:   39 VLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQP 115
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Mouse
Match: Mcat (malonyl CoA:ACP acyltransferase (mitochondrial) [Source:MGI Symbol;Acc:MGI:2388651])

HSP 1 Score: 83.1889 bits (204), Expect = 6.396e-19
Identity = 43/112 (38.39%), Postives = 69/112 (61.61%), Query Frame = 1 
Query:  571 QGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNP 906
            +GL+ ++ RA+ MQ A      G+L V    +S  + A   A+++C+  L + +P+CQ++ +LF +C+VI GH EAL F+   + +++   TK L VSG FHT LM  AV+P
Sbjct:    5 EGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCKS-LGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDP 115
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Mouse
Match: Mcat (malonyl CoA:ACP acyltransferase (mitochondrial) [Source:MGI Symbol;Acc:MGI:2388651])

HSP 1 Score: 78.5666 bits (192), Expect = 6.644e-18
Identity = 35/62 (56.45%), Postives = 52/62 (83.87%), Query Frame = 1 
Query:  385 LNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISF-EGVAFS 567
            L++T++CQPA++VAS+AA+EK+   QP +I+NC+AAAG+S+GE  +LVFAGA+ F EG + S
Sbjct:    5 LDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFSEGPSVS 66
[Close]
BLAST of PKS_AT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8IVS2|FABD_HUMAN (Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2)

HSP 1 Score: 262.307 bits (669), Expect = 8.471e-83
Identity = 131/319 (41.07%), Postives = 201/319 (63.01%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
            + LFPGQG Q+VGM + L+N P+V+ L+ +A  +L YDLL+L + G    L++T++CQPAI+VAS+AA+EK+   QP +IENC+AAAG+S+GE  +LVFAGA+ F       +GL+ +++RA+ MQ A      G+L V   P+S+ N A   A+++C+  L + +P+C+++ +LF +C+VI GH EAL F++  + +F+   T+ L VSGAFHTRLM  AV P   AL+ +D I +  ++V+SN     +     I +LL +Q+   V+WEQ +  +Y R      P T E+GP  QL   +   N  A+K Y  +  
Sbjct:   64 VLLFPGQGSQVVGMGRGLLNYPRVRELYAAARRVLGYDLLELSLHGPQETLDRTVHCQPAIFVASLAAVEKLHHLQPSVIENCVAAAGFSVGEFAALVFAGAMEFA------EGLYAVKIRAEAMQEASEAVPSGMLSVLGQPQSKFNFACLEAREHCK-SLGIENPVCEVSNYLFPDCRVISGHQEALRFLQKNSSKFHFRRTRMLPVSGAFHTRLMEPAVEPLTQALKAVD-IKKPLVSVYSNVHAHRYRHPGHIHKLLAQQLVSPVKWEQTMHAIYERKKGRGFPQTFEVGPGRQLGAILKSCNMQAWKSYSAVDV 374
[Close]
BLAST of PKS_AT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R3F5|FABD_MOUSE (Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Mus musculus OX=10090 GN=Mcat PE=1 SV=3)

HSP 1 Score: 261.151 bits (666), Expect = 2.167e-82
Identity = 130/319 (40.75%), Postives = 202/319 (63.32%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
            + LFPGQGCQ VGM   L+++P+V++L+++A  +L YDLL+LC+ G    L++T++CQPA++VAS+AA+EK+   QP +I+NC+AAAG+S+GE  +LVFAGA+ F       +GL+ ++ RA+ MQ A      G+L V    +S  + A   A+++C+  L + +P+CQ++ +LF +C+VI GH EAL F+   + +++   TK L VSG FHT LM  AV+P    L  I+ I +  + V SN +G  +T    I++LL +Q+   V+WEQ +  +Y R   +E P T E+GP  QL   +   N  A+K Y H+  
Sbjct:   62 VLLFPGQGCQAVGMGSGLLHLPRVRQLYEAAHRVLGYDLLELCLRGPQEDLDRTVHCQPAVFVASLAAVEKLHHLQPAVIDNCVAAAGFSVGEFAALVFAGAMDFS------EGLYAVKARAEAMQEASEAVPSGMLSVLGQRQSNFSFACLEAQEHCK-SLGIENPVCQVSNYLFPDCRVISGHLEALQFLRRNSAKYHFRRTKMLPVSGGFHTCLMEPAVDPLMKVLGSIN-IKKPLVAVHSNVSGQKYTHPQHIRKLLGQQVVSPVKWEQTMHSIYERKKGMEFPSTYEVGPGQQLGSILKCCNRQAWKSYSHVDV 372
[Close]
BLAST of PKS_AT domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8T3L6|FABD_DROME (Probable malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Drosophila melanogaster OX=7227 GN=beg PE=2 SV=2)

HSP 1 Score: 258.07 bits (658), Expect = 3.354e-81
Identity = 134/310 (43.23%), Postives = 191/310 (61.61%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNA 1164
            + LFPGQG Q VGM K+L+  P  +R+F+ A+ +LKYDLLK+C+EG   KLN+T + Q A+ V+S+AALE+++ E+P+ IE C+AAAG+SLGEIT+LV+A A+ F+      + L  ++VRA  MQ AC+   G + +    P++ L EA   A+Q+C +K  +  P C IA +++  CKV+ G+ EAL+F+E  AK F +   KRL VSGAFHT LM+ AV P   AL+ +  +    I V+SN  G  +     I   L KQI   V+WEQ L  +Y R   ++ P T E GP   L   + K N  A
Sbjct:   69 VMLFPGQGTQYVGMAKDLLRFPGARRIFELANEVLKYDLLKICLEGPREKLNRTEHAQLAVMVSSLAALEQLREERPKAIETCVAAAGFSLGEITALVYADALPFD------KALRLVQVRATAMQAACDQAAGAMAMTLYGPDTNLGEACARAQQWCLDK-GVESPYCGIANYMYPHCKVVAGNVEALEFLEQNAKSFKIRRMKRLAVSGAFHTPLMQSAVEPFTKALKTVR-LQDPVIRVYSNVDGKPYRHAKHILTQLPKQIVRPVKWEQTLHEMYERKQGVDFPRTFECGPGKGLVQVLEKVNAKA 370
[Close]
BLAST of PKS_AT domain-containing protein vs. UniProt/SwissProt
Match: sp|P71019|FABD_BACSU (Malonyl CoA-acyl carrier protein transacylase OS=Bacillus subtilis (strain 168) OX=224308 GN=fabD PE=3 SV=2)

HSP 1 Score: 131.339 bits (329), Expect = 1.185e-33
Identity = 102/315 (32.38%), Postives = 150/315 (47.62%), Query Frame = 1 
Query:  226 SAYIFLFPGQGCQIVGMCKNLIN-IPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIA---AAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFT-VEIGPTPQLKDTISKTN 1155
            S   FLFPGQG Q +GM K L   +P  +RLFD A   L+  L  L  EG + +L  T   QPA+   S+A LEK K       E+ I     AG+SLGE ++LV AGA+SF+   ++      +R R + M  A    +G +  +       L    EA KQ   +K+     + Q+A        VI G  + ++     AKE        L VSG FH+ LM+ A    +  L+  D I    + V SN +  + T +++IK  L++Q+   V++E+ + +L     I E   T +EIGP   L   + K N
Sbjct:    2 SKIAFLFPGQGSQFIGMGKELYEQVPAAKRLFDEADETLETKLSSLIFEGDAEELTLTYNAQPALLTTSIAVLEKFK-------ESGITPDFTAGHSLGEYSALVAAGALSFKDAVYT------VRKRGEFMNEAVPAGEGAMAAI-------LGMDAEALKQVT-DKVTEEGNLVQLANLNCPGQIVISGTAKGVELASELAKENGAKRAIPLEVSGPFHSELMKPAAEKLKEVLDACD-IKDADVPVISNVSADVMTEKADIKEKLIEQLYSPVRFEESINKL-----IAEGVTTFIEIGPGKVLSGLVKKVN 289
[Close]
BLAST of PKS_AT domain-containing protein vs. UniProt/SwissProt
Match: sp|O34825|PKSC_BACSU (Polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase PksC OS=Bacillus subtilis (strain 168) OX=224308 GN=pksC PE=1 SV=1)

HSP 1 Score: 110.153 bits (274), Expect = 4.388e-26
Identity = 98/315 (31.11%), Postives = 150/315 (47.62%), Query Frame = 1 
Query:  238 FLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVA-SMAALEKIKLEQ--PELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQM--IDPICQIATHLFKECKVIGGHTEALDFVES-FAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNA 1164
            ++FPGQG Q  GM   L +  + + L D A  +L Y + +LC+E   S LN+T + QPA+YV  +++ L+KI+ E+  P+ +      AG+SLGE  +L  A A  FE       GL  +R R + M L  N   GG+  V  + E ++ +AL   K+Y    + +  ++   QI         VI G  + ++   S F     + +   LNVSGAFH+R M  A       L      +   I V SN     +T +  +K+ L  QI HSV+W   +  L M+   +E     E+GP   L   I +   +A
Sbjct:    4 YVFPGQGSQKQGMGSGLFD--EFKELTDQADEILGYSIKRLCLENPYSNLNKTQFTQPALYVVNALSYLKKIRDEEVKPDFV------AGHSLGEYNALFAAEAFDFE------TGLQLVRKRGELMSLISN---GGMAAVMGLNEEQVAKAL---KEYHLHDVDIANVNAPYQI---------VISGKKDEIEKAASLFETMTEVTMVLPLNVSGAFHSRYMNKAKEEFEEFLHAF-YFSPPSIPVISNVYAKPYTYEF-MKQTLADQINHSVKWTDSISYL-MKKGHMEFE---EVGPGNVLTGLIHRIKKDA 283
[Close]
BLAST of PKS_AT domain-containing protein vs. TrEMBL
Match: A0A0X3NVI6 (Putative malonyl-CoA-acyl carrier protein transacylase (Fragment) OS=Schistocephalus solidus OX=70667 GN=FABD PE=4 SV=1)

HSP 1 Score: 309.301 bits (791), Expect = 3.786e-99
Identity = 153/339 (45.13%), Postives = 215/339 (63.42%), Query Frame = 1 
Query:  172 QPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDP-ICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHI 1185
            +P  W  YY  P T       + LFPGQG Q VGM KN+I++P V+ +F+SAS++L+ DLLK+C+EG   KL +TI+CQPA+YV S+AA +K++LE PE IE C+A AGYS+GEI +L FAG  +FE      +GLH +RVRA+ MQ A +    G+  V +  +S+L  AL AA  +C+E+L+M  P +CQ+A ++  ECKVI G+ EAL+F+ES  ++F LG  KRL V+GAFHT LM  AV+  ++AL+R+       I V SN     +     + R L KQ+   + WEQ L  LY RP  +  P T E+GP  +L  T+   N  AFK+Y+ +
Sbjct:   14 RPDTWCQYYDRPVTVPIEKTSVLLFPGQGSQFVGMAKNVIDVPGVKDMFESASSILRTDLLKICLEGPPEKLKKTIHCQPAVYVTSLAAAKKLQLECPEAIEQCVATAGYSVGEIAALAFAGTFTFE------EGLHLLRVRAESMQRASDLLPSGMAWVTLGHDSQLRAALAAAINHCKEELKMETPVVCQVAAYISPECKVIAGNIEALEFIESHLEQFRLGSMKRLEVAGAFHTPLMLPAVDAVKHALKRLPPARAPAIPVVSNVDAEPYGQAIGVSRRLTKQLTRPLCWEQTLHALYARPEEVPFPKTFEVGPGRKLGVTLRMVNAKAFKRYESV 346
[Close]
BLAST of PKS_AT domain-containing protein vs. TrEMBL
Match: A0A068Y7M9 (Malonyl coenzyme A acyl carrier protein transacylase OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000839400 PE=4 SV=1)

HSP 1 Score: 309.686 bits (792), Expect = 5.094e-99
Identity = 154/342 (45.03%), Postives = 219/342 (64.04%), Query Frame = 1 
Query:  163 DYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDP-ICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHI 1185
            D  +P  W  Y+  P+     S  + LFPGQG Q VGM KNLI +  V+ +F++AS++L+ +LLK C+EG + KL Q I+CQPA+YV S+AA +K++++ PEL+E C+AAAGYS+GEI +LV+AGA +FE      +GLH IRVRA+ MQ AC+   GG+L V +  +S+L  AL AA  YC+E+L++  P ICQIA  L  +CKVI G+ EALD++   A++F LG  +RL+V+GAFHT LM  AV P ++AL+R+       I V SN     +   S +   L+KQI   + WEQ L  L+ RP     P  VE+GP  Q+  ++   N  AF +Y+ +
Sbjct:   31 DGQRPDGWCQYHDRPSQEPIESTSVLLFPGQGSQFVGMAKNLIGVKGVKEMFETASSILRTNLLKTCLEGPAEKLKQNIHCQPAMYVTSLAAAKKLQVDSPELVEKCVAAAGYSVGEIAALVYAGAYTFE------EGLHLIRVRAEAMQRACDLIPGGMLTVYLSHDSQLRTALSAAINYCKEELKLSVPIICQIACFLGPDCKVIAGNNEALDYIMEHAQQFRLGPLRRLDVAGAFHTPLMLPAVEPLKHALQRVGSARTPCIPVVSNVDAEPYGKGSTVSLRLIKQITRPLCWEQTLHALFSRPEGAPFPRAVEVGPGRQIGASLRMVNSKAFVRYESV 366
[Close]
BLAST of PKS_AT domain-containing protein vs. TrEMBL
Match: A0A0R3W511 (PKS_AT domain-containing protein OS=Taenia asiatica OX=60517 GN=TASK_LOCUS5179 PE=4 SV=1)

HSP 1 Score: 308.145 bits (788), Expect = 1.696e-98
Identity = 156/339 (46.02%), Postives = 218/339 (64.31%), Query Frame = 1 
Query:  172 QPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDP-ICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHI 1185
            +P  W  YY  P+     S  + LFPGQG Q VGM KNL+ I  V+ +F++AS++L+ +LL+ C+EG + KL Q I+CQPAIYV S+AA +K++++ PEL+E C+AAAG+S+GEIT+LV+AGA +FE      +GLH IRVRA+ MQ AC+   GG+L V +  +S+L  AL AA  YC+E+L++  P ICQI+  L  ECKVI G+ EALD++   A++F L   +RL+V+GAFHT LM  AV P ++AL+R+       I V SN     +   S +   L KQI   + WEQ L  L+ RP     P TVE+GP  QL  T+   N  AF +Y+ +
Sbjct:   34 RPDVWCQYYDRPSQEPIESTSVLLFPGQGSQFVGMAKNLLGIKGVKEMFEAASSILRTNLLRTCLEGPAEKLKQNIHCQPAIYVTSLAAAKKLEIDSPELVEKCVAAAGFSVGEITALVYAGAYTFE------EGLHLIRVRAEAMQRACDLIPGGMLTVHLSHDSQLRMALSAAINYCKEELKLDVPIICQISCFLGPECKVIAGNNEALDYIMGHAQQFRLRSLRRLDVAGAFHTPLMLPAVEPLKHALQRVGSARTPCIPVVSNVDAEPYGKGSTVSLRLTKQITRPLCWEQSLHALFGRPDGAPFPRTVEVGPGRQLGATLRMVNTKAFARYESV 366
[Close]
BLAST of PKS_AT domain-containing protein vs. TrEMBL
Match: A0A075AJ56 (PKS_AT domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_12760 PE=4 SV=1)

HSP 1 Score: 307.76 bits (787), Expect = 2.349e-98
Identity = 156/382 (40.84%), Postives = 229/382 (59.95%), Query Frame = 1 
Query:   34 YAELMQKMLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYK 1179
            Y  L+  + KI+ +   Y  L R  C    S       +RG       K W  Y + P  T      +FLFPGQG Q  GM KNL+ +P+V+ +F  A+ +L+ DLLK C+EG  SKL+QT++CQPA Y+ S+A++ K++ ++ E++ NC+A AG+S+GE+T+LVFAG+++FE      QGLH IRVRA+ MQ AC+  KG +  V +  +S+L  A+ AA ++C+   ++ +P C+IA +L+ +CKV+ GH +A++F+E  A +F +   KRL V+GAFHT LMR AV P   A+ RID +    I V S      +T+   ++R L  Q+   V+WEQ L  LY+RP     P TVE GP  QL   +  TN  AF  Y+
Sbjct:    2 YLRLVAHISKIRTVCTHY--LSRKLCQTDSS-------VRGSW-----KGWTQYENRPQHTDIEQTSVFLFPGQGSQFAGMGKNLLRVPKVREMFQCANEMLRTDLLKTCLEGPQSKLDQTVHCQPATYIISLASVAKLQEDEDEVVRNCVATAGFSVGEVTALVFAGSMTFE------QGLHVIRVRAEAMQKACDRIKGAMTSVFLSHDSQLKLAISAALEHCKTHYKLENPECRIANYLYSDCKVVAGHLQAIEFIEQHAPQFRIRRVKRLPVNGAFHTSLMRSAVEPVSRAVSRIDQLKSPSIPVVSALDILPYTTVESVRRKLSLQLVRPVKWEQTLHALYIRPPDTPFPVTVEPGPGKQLGAMLRMTNRKAFAHYR 363
[Close]
BLAST of PKS_AT domain-containing protein vs. TrEMBL
Match: A0A068W8P7 (Malonyl coenzyme A acyl carrier protein transacylase OS=Echinococcus granulosus OX=6210 GN=EgrG_000839400 PE=4 SV=1)

HSP 1 Score: 307.375 bits (786), Expect = 4.125e-98
Identity = 153/342 (44.74%), Postives = 218/342 (63.74%), Query Frame = 1 
Query:  163 DYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDP-ICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHI 1185
            D  +P  W  Y+  P+     S  + LFPGQ  Q VGM KNLI +  V+ +F++AS++L+ +LL+ C+EG + KL Q I+CQPAIYV S+AA +K++++ PEL+E C+AAAGYS+GEI +LV+AGA +FE      +GLH IRVRA+ MQ AC+   GG+L V +  +S+L  AL AA  YC+E+L++  P ICQIA  L  +CKVI G+ EALD++   A++F LG  +RL+V+GAFHT LM  AV P ++AL+R+       I V SN     +   S +   L+KQI   + WEQ L  L+ RP     P  VE+GP  Q+  ++   N  AF +Y+ +
Sbjct:   31 DGQRPDAWCQYHDRPSQEPIESTSVLLFPGQSSQFVGMAKNLIGVKGVKEMFETASSILRTNLLRTCLEGPAEKLKQNIHCQPAIYVTSLAAAKKLQVDSPELVEKCVAAAGYSVGEIAALVYAGAYTFE------EGLHLIRVRAEAMQRACDLIPGGMLTVYLSHDSQLRTALSAAINYCKEELKLSVPIICQIACFLGPDCKVIAGNNEALDYIMEHAQQFRLGPLRRLDVAGAFHTPLMLPAVEPLKHALQRVGSARTPCIPVVSNVDAEPYGKGSTVSLRLIKQITRPLCWEQTLHALFSRPEGAPFPRAVEVGPGRQIGASLRMVNSKAFARYESV 366
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Cavefish
Match: mcat (malonyl-CoA-acyl carrier protein transacylase [Source:NCBI gene;Acc:103032777])

HSP 1 Score: 263.462 bits (672), Expect = 2.665e-84
Identity = 132/320 (41.25%), Postives = 197/320 (61.56%), Query Frame = 1 
Query:  229 AYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIS 1188
            A + LFPGQG Q VGM + L+    V+ +F  A  +L YDLL LC+ G    L +T++CQPA++V S+AA+E++  E PE +ENC+ AAG+S+GE  +LVF+GA+ F    F+      ++VRA+ MQ A + T+ G+L V    ++    A   A+++C   L + +P+C IA +LF + +VI GH EALDF++  +++ +   T++L VSGAFHT LM  AV P R+ L  +D + +  I+V SN  G  +   + +++ LVKQ+   V+WEQ L  +Y R    + P T E+GP  QL  T+ K N  AFK YKHI 
Sbjct:   61 ASVLLFPGQGSQFVGMGRGLLEYGNVREMFSVAQKVLGYDLLDLCLNGPEEDLMKTVHCQPAVFVTSLAAVERLNQENPEAVENCVTAAGFSVGEFAALVFSGAMDFAEALFA------VKVRAEAMQKASDQTRSGMLSVIGKNQANYKHACLQAREHCL-SLGIQNPVCSIANYLFPDGRVIAGHQEALDFLQKNSRKLHFARTRQLPVSGAFHTSLMEPAVEPLRDVLRELD-VRRPIISVHSNVNGKRYMHDNHVRQQLVKQLVSPVKWEQTLHEIYERNQGEDFPHTYEVGPGKQLGATLQKCNMKAFKNYKHID 372
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Nematostella
Match: EDO29853 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T2G4])

HSP 1 Score: 167.933 bits (424), Expect = 9.167e-49
Identity = 109/314 (34.71%), Postives = 168/314 (53.50%), Query Frame = 1 
Query:  238 FLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIEN------CIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYC-QEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTV-EIGPTPQLKDTISKTN 1155
            FLFPGQG   VGMC+   N   +Q  F   + L+ YDLLK+C+EG + +LN+T   Q A+ VAS+AAL K   +   +  N        +AAG+S+GE ++LVFA A++          L  + VRA+ MQ A  N   G++ V+ + + +L+E   AAK++   +  Q  +    IA +L+ +C+VI    +A+D++  F          RL V+GAFH+ LM  A      AL+ ++ I      V+SN TG  + S  E++RLLV+Q+   V W Q++  L       ++P TV E GP  QL   + + +
Sbjct:    4 FLFPGQGAHFVGMCRRFANDRDIQNFFKRVNELIGYDLLKICVEGPAERLNRTENSQLAVLVASLAAL-KWHEKHSSMYLNEQGDPALFSAAGFSVGEYSALVFAQALTLS------DALKVVSVRAKAMQKASGNNPSGMVTVKGLNDIQLDELCGAAKEWASSQHPQQQETEAVIANYLYPKCRVIACSLKAMDYIIQFGN----SKVSRLPVNGAFHSPLMAIAQPALEEALDNVE-IRPPAFPVYSNVTGRPYGSVEEVRRLLVQQLVQPVLWHQLVTSLIRD----KNPVTVYEAGPGRQLNTILCRID 301
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Nematostella
Match: EDO27007 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7TAG4])

HSP 1 Score: 72.0182 bits (175), Expect = 1.085e-15
Identity = 43/108 (39.81%), Postives = 66/108 (61.11%), Query Frame = 1 
Query:  238 FLFPGQGCQIVGMCKNLI-NIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLE--QPELIENCIAAAGYSLGEITSLVFAGAISFE 552
            ++FPGQG Q  GM  +L  N P  Q LF+ A+ +L + +  +  EG+  +L QT   QPAI++ S+  L K+  +  QPE++      AG+SLGE+++LV  G +SFE
Sbjct:    4 YIFPGQGAQFTGMGLDLYENSPIAQGLFEKANEILGFSITDVMFEGTPEELKQTKVTQPAIFLHSV-ILAKVLGDSFQPEMV------AGHSLGELSALVANGVLSFE 104
[Close]
BLAST of PKS_AT domain-containing protein vs. Ensembl Medaka
Match: mcat (malonyl-CoA-acyl carrier protein transacylase [Source:NCBI gene;Acc:101172545])

HSP 1 Score: 265.003 bits (676), Expect = 5.617e-85
Identity = 130/318 (40.88%), Postives = 198/318 (62.26%), Query Frame = 1 
Query:  235 IFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIS 1188
            + LFPGQG Q VGM   L+  P V+ +F  A  +L YDLL LC+ G   +L +T++CQPA++V+S+AA+E++  E P+ +E C+AAAG+S+GE  +LVF+GA+ F       + L+ ++VRA+ MQ A      G+L V   P+++  +A   AK++C+  L + +P+C +A +LF + +VI GH +ALDF++  ++  +   TK L VSGAFHT LM  A  P R+AL  ++ + + +I V+SN  G  + S+S I+R L KQ+   V+WEQ L  +Y R      P T E+GP  QL  T+ K N  AF+ Y H+ 
Sbjct:   53 VLLFPGQGSQFVGMVGGLLQYPNVRDMFSVAQRILGYDLLSLCLNGPEKELQKTVHCQPAVFVSSLAAVERLNHENPKAVETCVAAAGFSVGEFAALVFSGAMDFA------EALYVVKVRAEAMQRASELVPSGMLSVIGRPQAQYKQACLQAKEHCR-SLGIQEPVCSVANYLFPDGRVIAGHQQALDFLQQKSRSLHFIRTKLLPVSGAFHTDLMASASEPLRDALRDVE-VRRPEIRVYSNVDGKRYMSESHIRRQLAKQVVSPVKWEQTLHEIYERTQGESFPHTYEVGPGKQLGATLQKCNRKAFQTYAHVD 362
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BLAST of PKS_AT domain-containing protein vs. Planmine SMEST
Match: SMESG000054688.1 (SMESG000054688.1)

HSP 1 Score: 774.622 bits (1999), Expect = 0.000e+0
Identity = 376/382 (98.43%), Postives = 376/382 (98.43%), Query Frame = 1 
Query:   46 MQKMLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
            MQKMLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEG      GLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST
Sbjct:    1 MQKMLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEG------GLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 376
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BLAST of PKS_AT domain-containing protein vs. Planmine SMEST
Match: SMESG000054688.1 (SMESG000054688.1)

HSP 1 Score: 768.844 bits (1984), Expect = 0.000e+0
Identity = 373/379 (98.42%), Postives = 373/379 (98.42%), Query Frame = 1 
Query:   55 MLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 1191
            MLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEG      GLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST
Sbjct:    1 MLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEG------GLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYKHIST 373
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BLAST of PKS_AT domain-containing protein vs. Planmine SMEST
Match: SMESG000054426.1 (SMESG000054426.1)

HSP 1 Score: 373.629 bits (958), Expect = 5.900e-128
Identity = 181/351 (51.57%), Postives = 250/351 (71.23%), Query Frame = 1 
Query:  130 SNDLYYIRGE-IDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYK 1179
            S DL  ++    D  + K W+LY S P +   +S  IFLFPG G Q VGMC+NL+ +PQV+RLF+SAS  L Y+LL++C+EG   KLN   +  PAIYVA++AALEKIK ++PELIE+CIAAAGY LGEI+SLVFAG +SFE      QGLH +RVRA++++ AC N KGGLL V++ P+S L + + AAK+YC EKL + +P+C+++T+L+ EC++IGGH EA++F+++FA +F L  T+ ++ SGAFHT LM  AV PC+ AL  I  IN+QK+ VFSNATG ++T     K+L+ +QI   +QWEQI++R+YMRP +   P T+EIG    LK T+   N  A K Y+
Sbjct:    3 SKDLLEVKSRNYDIEKYKTWSLYTSTPESFDQSSTNIFLFPGYGAQYVGMCRNLVELPQVKRLFESASDYLNYNLLEMCLEGPKDKLNTISHSHPAIYVATIAALEKIKQDEPELIEHCIAAAGYDLGEISSLVFAGVLSFE------QGLHIVRVRAEEIEKACQNVKGGLLEVKLQPKSGLKKIMMAAKKYCIEKLNIENPVCELSTNLYTECRIIGGHIEAIEFIQTFANDFYLKSTRIIDSSGAFHTNLMEAAVKPCQIALRDIGEINKQKVIVFSNATGNLYTPICRFKKLIGEQISKPIQWEQIIMRMYMRPKLSGQPRTIEIGSGSFLKKTVKNVNAIAAKNYR 347
[Close]
BLAST of PKS_AT domain-containing protein vs. Planmine SMEST
Match: SMESG000054426.1 (SMESG000054426.1)

HSP 1 Score: 373.244 bits (957), Expect = 2.103e-127
Identity = 181/351 (51.57%), Postives = 250/351 (71.23%), Query Frame = 1 
Query:  130 SNDLYYIRGE-IDYSQPKNWNLYYSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKYDLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAAGYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLLIVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTEALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQQKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEHPFTVEIGPTPQLKDTISKTNPNAFKKYK 1179
            S DL  ++    D  + K W+LY S P +   +S  IFLFPG G Q VGMC+NL+ +PQV+RLF+SAS  L Y+LL++C+EG   KLN   +  PAIYVA++AALEKIK ++PELIE+CIAAAGY LGEI+SLVFAG +SFE      QGLH +RVRA++++ AC N KGGLL V++ P+S L + + AAK+YC EKL + +P+C+++T+L+ EC++IGGH EA++F+++FA +F L  T+ ++ SGAFHT LM  AV PC+ AL  I  IN+QK+ VFSNATG ++T     K+L+ +QI   +QWEQI++R+YMRP +   P T+EIG    LK T+   N  A K Y+
Sbjct:   31 SKDLLEVKSRNYDIEKYKTWSLYTSTPESFDQSSTNIFLFPGYGAQYVGMCRNLVELPQVKRLFESASDYLNYNLLEMCLEGPKDKLNTISHSHPAIYVATIAALEKIKQDEPELIEHCIAAAGYDLGEISSLVFAGVLSFE------QGLHIVRVRAEEIEKACQNVKGGLLEVKLQPKSGLKKIMMAAKKYCIEKLNIENPVCELSTNLYTECRIIGGHIEAIEFIQTFANDFYLKSTRIIDSSGAFHTNLMEAAVKPCQIALRDIGEINKQKVIVFSNATGNLYTPICRFKKLIGEQISKPIQWEQIIMRMYMRPKLSGQPRTIEIGSGSFLKKTVKNVNAIAAKNYR 375
The following BLAST results are available for this feature:
BLAST of PKS_AT domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 3
Match NameE-valueIdentityDescription
MCAT1.764e-8341.07malonyl-CoA-acyl carrier protein transacylase [Sou... [more]
MCAT3.656e-3654.29malonyl-CoA-acyl carrier protein transacylase [Sou... [more]
MCAT4.889e-1056.25malonyl-CoA-acyl carrier protein transacylase [Sou... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1
Match NameE-valueIdentityDescription
C50D2.92.043e-6634.97pep chromosome:WBcel235:II:88221:91519:-1 gene:WBG... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
beg3.346e-8243.23gene:FBgn0036691 transcript:FBtr0075278[more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
mcat5.891e-8340.56malonyl CoA:ACP acyltransferase (mitochondrial) [S... [more]
mcat1.265e-4939.47malonyl CoA:ACP acyltransferase (mitochondrial) [S... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mcat1.161e-3534.95malonyl-CoA-acyl carrier protein transacylase [Sou... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4
Match NameE-valueIdentityDescription
Mcat3.097e-8340.75malonyl CoA:ACP acyltransferase (mitochondrial) [S... [more]
Mcat6.611e-2450.65malonyl CoA:ACP acyltransferase (mitochondrial) [S... [more]
Mcat6.396e-1938.39malonyl CoA:ACP acyltransferase (mitochondrial) [S... [more]
Mcat6.644e-1856.45malonyl CoA:ACP acyltransferase (mitochondrial) [S... [more]
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BLAST of PKS_AT domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q8IVS2|FABD_HUMAN8.471e-8341.07Malonyl-CoA-acyl carrier protein transacylase, mit... [more]
sp|Q8R3F5|FABD_MOUSE2.167e-8240.75Malonyl-CoA-acyl carrier protein transacylase, mit... [more]
sp|Q8T3L6|FABD_DROME3.354e-8143.23Probable malonyl-CoA-acyl carrier protein transacy... [more]
sp|P71019|FABD_BACSU1.185e-3332.38Malonyl CoA-acyl carrier protein transacylase OS=B... [more]
sp|O34825|PKSC_BACSU4.388e-2631.11Polyketide biosynthesis malonyl CoA-acyl carrier p... [more]
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BLAST of PKS_AT domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0X3NVI63.786e-9945.13Putative malonyl-CoA-acyl carrier protein transacy... [more]
A0A068Y7M95.094e-9945.03Malonyl coenzyme A acyl carrier protein transacyla... [more]
A0A0R3W5111.696e-9846.02PKS_AT domain-containing protein OS=Taenia asiatic... [more]
A0A075AJ562.349e-9840.84PKS_AT domain-containing protein OS=Opisthorchis v... [more]
A0A068W8P74.125e-9844.74Malonyl coenzyme A acyl carrier protein transacyla... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mcat2.665e-8441.25malonyl-CoA-acyl carrier protein transacylase [Sou... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PKS_AT domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of PKS_AT domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2
Match NameE-valueIdentityDescription
EDO298539.167e-4934.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO270071.085e-1539.81Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of PKS_AT domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
mcat5.617e-8540.88malonyl-CoA-acyl carrier protein transacylase [Sou... [more]
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BLAST of PKS_AT domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 4
Match NameE-valueIdentityDescription
SMESG000054688.10.000e+098.43SMESG000054688.1[more]
SMESG000054688.10.000e+098.42SMESG000054688.1[more]
SMESG000054426.15.900e-12851.57SMESG000054426.1[more]
SMESG000054426.12.103e-12751.57SMESG000054426.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035351 ID=SMED30035351|Name=PKS_AT domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1266bp
TTTTAACATTTGTTTTAATATCTATGATCTGGGTATGCTGAATTGATGCA
AAAAATGTTAAAAATAAAAAATATTTCTAAAAGTTACAAGTTCTTATATC
GGCTTTTTTGTAGCGAAACAGAATCGCCATCAAACGATTTATATTATATT
CGAGGGGAAATAGATTACAGTCAGCCGAAGAACTGGAATTTATATTACTC
GTTGCCTACAACTACTAAATTCGCATCTGCATATATATTTCTATTCCCGG
GTCAGGGATGTCAAATAGTTGGAATGTGTAAAAATCTTATTAATATACCA
CAAGTTCAAAGATTATTTGATTCTGCTTCAACATTACTTAAGTATGATTT
ACTAAAGCTTTGTATTGAAGGATCAAGTTCAAAATTAAACCAAACTATTT
ACTGTCAACCTGCAATATATGTGGCATCAATGGCTGCTCTTGAAAAAATA
AAATTAGAACAACCTGAATTAATTGAGAATTGCATTGCTGCAGCTGGTTA
TAGTTTAGGAGAAATTACTTCCCTCGTATTTGCCGGAGCTATATCCTTTG
AAGGAGTAGCATTTTCATTTCAAGGATTGCATTTTATTCGTGTCAGAGCC
CAACAAATGCAGCTTGCTTGCAATAATACCAAAGGCGGCTTGTTAATAGT
TAGAATAATCCCAGAGTCAAGATTAAATGAAGCTTTGGAAGCAGCTAAAC
AATACTGCCAGGAAAAACTGCAGATGATAGACCCTATTTGCCAAATTGCT
ACTCATTTATTTAAAGAATGCAAAGTCATTGGGGGTCACACAGAAGCTCT
CGATTTTGTCGAATCTTTTGCAAAGGAATTCAATTTAGGATTGACTAAGC
GTTTGAATGTCAGTGGTGCATTTCATACTCGACTGATGCGAGACGCGGTT
AATCCTTGTCGCAATGCTCTTGAACGGATTGATGGAATTAATCAACAGAA
AATAAATGTCTTTTCAAATGCAACTGGAACAATTCATACTTCTCAAAGTG
AAATTAAGCGATTACTCGTGAAACAAATATGCCATTCAGTTCAGTGGGAA
CAGATTTTGGTCCGGCTATATATGCGACCCAGTATTATCGAACATCCATT
CACTGTCGAGATTGGACCGACTCCACAATTAAAAGACACAATTAGTAAAA
CAAATCCGAATGCATTTAAAAAATATAAACATATATCGACATAAATTGGT
TGAAATTATTTTTCAATGATTTTAATTGGTCGATTTTTTGAACTGTATTT
AAATAAAAATTTAAAC
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protein sequence of SMED30035351-orf-1

>SMED30035351-orf-1 ID=SMED30035351-orf-1|Name=SMED30035351-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=383bp
MQKMLKIKNISKSYKFLYRLFCSETESPSNDLYYIRGEIDYSQPKNWNLY
YSLPTTTKFASAYIFLFPGQGCQIVGMCKNLINIPQVQRLFDSASTLLKY
DLLKLCIEGSSSKLNQTIYCQPAIYVASMAALEKIKLEQPELIENCIAAA
GYSLGEITSLVFAGAISFEGVAFSFQGLHFIRVRAQQMQLACNNTKGGLL
IVRIIPESRLNEALEAAKQYCQEKLQMIDPICQIATHLFKECKVIGGHTE
ALDFVESFAKEFNLGLTKRLNVSGAFHTRLMRDAVNPCRNALERIDGINQ
QKINVFSNATGTIHTSQSEIKRLLVKQICHSVQWEQILVRLYMRPSIIEH
PFTVEIGPTPQLKDTISKTNPNAFKKYKHIST*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000429neoblast
PLANA:0002109X1 cell
PLANA:0002111X2 cell
Vocabulary: INTERPRO
TermDefinition
IPR020801PKS_acyl_transferase
IPR014043Acyl_transferase
IPR001227Ac_transferase_dom_sf
IPR016035Acyl_Trfase/lysoPLipase
Vocabulary: biological process
TermDefinition
GO:0008152metabolic process
GO:0006629lipid metabolic process
GO:0006631fatty acid metabolic process
GO:0006633fatty acid biosynthetic process
Vocabulary: molecular function
TermDefinition
GO:0016740transferase activity
GO:0003723RNA binding
GO:0003824catalytic activity
GO:0004314[acyl-carrier-protein] S-malonyltransferase activity
Vocabulary: cellular component
TermDefinition
GO:0005739mitochondrion
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR020801Polyketide synthase, acyl transferase domainSMARTSM00827PKS_ATcoord: 66..378
e-value: 6.6E-9
score: -53.4
NoneNo IPR availableGENE3DG3DSA:3.30.70.250coord: 195..272
e-value: 3.7E-74
score: 251.9
NoneNo IPR availablePANTHERPTHR47170FAMILY NOT NAMEDcoord: 56..381
IPR001227Acyl transferase domain superfamilyGENE3DG3DSA:3.40.366.10coord: 66..362
e-value: 3.7E-74
score: 251.9
IPR016035Acyl transferase/acyl hydrolase/lysophospholipaseSUPERFAMILYSSF52151FabD/lysophospholipase-likecoord: 64..373