DUF4371 domain-containing protein

Overview
NameDUF4371 domain-containing protein
Smed IDSMED30035318
Length (bp)1771
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of DUF4371 domain-containing protein (SMED30035318) t-SNE clustered cells

Violin plots show distribution of expression levels for DUF4371 domain-containing protein (SMED30035318) in cells (dots) of each of the 12 neoblast clusters.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035318

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
gutSMED30035318SMESG000019281.1 dd_Smed_v4_5254_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035318SMESG000019281.1 dd_Smed_v4_5254_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035318SMESG000019281.1 dd_Smed_v4_5254_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
enteric muscle cellSMED30035318SMESG000019281.1 dd_Smed_v4_5254_0_1dd_Smed_v4PMID:30471994
Scimone et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Human
Match: GTF2IRD2B (GTF2I repeat domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33125])

HSP 1 Score: 205.682 bits (522), Expect = 3.471e-56
Identity = 117/342 (34.21%), Postives = 176/342 (51.46%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRI---------CAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y   T  +R  K   LK  L                                         ++ L+  ++  CPE K +F + S + ++  + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F++V+++L    + W +L  V + G   M  +  G+V ++          AEL++I         CIIH ESLC   L  M  +M+ V+ +VN+I   GL H +F   L E+DS+    L+YT
Sbjct:  418 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGL-----------------------------------------RKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSIC--------CIIHPESLCAQKL-KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYT 709
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Human
Match: GTF2IRD2B (GTF2I repeat domain containing 2B [Source:HGNC Symbol;Acc:HGNC:33125])

HSP 1 Score: 205.297 bits (521), Expect = 8.230e-56
Identity = 117/342 (34.21%), Postives = 176/342 (51.46%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRI---------CAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y   T  +R  K   LK  L                                         ++ L+  ++  CPE K +F + S + ++  + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F++V+++L    + W +L  V + G   M  +  G+V ++          AEL++I         CIIH ESLC   L  M  +M+ V+ +VN+I   GL H +F   L E+DS+    L+YT
Sbjct:  585 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGL-----------------------------------------RKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSIC--------CIIHPESLCAQKL-KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYT 876
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Human
Match: GTF2IRD2 (GTF2I repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30775])

HSP 1 Score: 202.986 bits (515), Expect = 3.107e-55
Identity = 117/342 (34.21%), Postives = 175/342 (51.17%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRI---------CAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y      +R  K   LK  L                                         ++ L+  ++  CPE K +F + S + ++  + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F +V+++L +  + W KL  V + G   M  +  G+V ++          AEL++I         CIIH ESLC   L  M  +M+ V+ +VN+I   GL H +F   L E+DS+    L+YT
Sbjct:  418 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMERMRDEKLHELKKGL-----------------------------------------RKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLKNFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSIC--------CIIHPESLCAQKL-KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYT 709
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Human
Match: GTF2IRD2 (GTF2I repeat domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30775])

HSP 1 Score: 202.986 bits (515), Expect = 6.068e-55
Identity = 117/342 (34.21%), Postives = 175/342 (51.17%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRI---------CAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y      +R  K   LK  L                                         ++ L+  ++  CPE K +F + S + ++  + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F +V+++L +  + W KL  V + G   M  +  G+V ++          AEL++I         CIIH ESLC   L  M  +M+ V+ +VN+I   GL H +F   L E+DS+    L+YT
Sbjct:  580 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMERMRDEKLHELKKGL-----------------------------------------RKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLKNFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSIC--------CIIHPESLCAQKL-KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYT 871
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Human
Match: EPM2AIP1 (EPM2A interacting protein 1 [Source:HGNC Symbol;Acc:HGNC:19735])

HSP 1 Score: 129.798 bits (325), Expect = 3.824e-31
Identity = 87/338 (25.74%), Postives = 160/338 (47.34%), Query Frame = 3 
Query:   72 MSSRKRKI-ADEGRVFNEEWNSKYFFTE--NGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLK------ASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            M+ ++ K+  DE  VF  EW  +Y   E   G    CL+C + +   +E +V+RHYE EHE   + +    R      L+      AS T ++   R           +   +  L+A + R + + +FV +C+  +  ++ PE  ++ Q + LS     +R+  I  NL  QL  +A+ F  YSLA+D+   +     L++FIRG+  +  V E+L ++ +L    +   L   + E+L +  L  +++  +TT     M G  +G+V  +  +  +  C N + +   +H E L  +    +  I+NT+   +  I+  G++  +F+  L E +SE
Sbjct:    3 MTPKRSKMEVDEALVFRPEWTQRYLVVEPPEGDGALCLVCRRLIVATRERDVRRHYEAEHEYYERYVADGERAALVERLRQGDLPVASFTPEERAAR-----------AGLGLCRLLALKGRGWGEGDFVYQCMEVLLREVLPEHVSVLQGVDLSPDITRQRILSIDRNLRNQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGPELEVQEDLLTIINLTHHFSVGALMSAILESLQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLE-LLSSYDVDVNQIINTISEWIVLIKTRGVRRPEFQTLLTESESE 328
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Celegans
Match: trf-1 (TNF Receptor Associated Factor (TRAF) homolog; TRF-1 [Source:UniProtKB/TrEMBL;Acc:G5EG80])

HSP 1 Score: 56.6102 bits (135), Expect = 2.798e-8
Identity = 36/94 (38.30%), Postives = 48/94 (51.06%), Query Frame = -1 
Query: 1220 IFG-QLEWKIQNVSQQERVK------HIYSNPFYSVKFGYKM----CLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKP 1468
            +FG QL WKI  + Q+           I+S PF S +FGYKM    CL          I +Y  LL+GEFD  L WPF   + I L++ +N +P
Sbjct:  260 MFGPQLIWKIDKLQQRTNEAKSGADTTIFSVPFMSHRFGYKMMACACLFGDGSSAGKSISLYVLLLKGEFDPTLEWPFHRAIKISLLD-QNPRP 352
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Celegans
Match: trf-2 (TNF Receptor Associated Factor (TRAF) homolog [Source:UniProtKB/TrEMBL;Acc:Q9N586])

HSP 1 Score: 50.447 bits (119), Expect = 1.934e-6
Identity = 24/63 (38.10%), Postives = 39/63 (61.90%), Query Frame = -1 
Query: 1238 KHIYSNPFYSVKFGYKM-CLSAYF---LKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELIN 1414
            + IYS PFYS  +GYKM  ++A +   L   +   ++  L++GE+DD L WPF+  VT  +++
Sbjct:  181 RSIYSQPFYSHGYGYKMMAVAAPYGDGLAFREYFSVFVCLMKGEWDDILEWPFRCDVTFSILS 243
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Zebrafish
Match: AL928808.1 (pep chromosome:GRCz11:20:17257101:17259573:-1 gene:ENSDARG00000101333.2 transcript:ENSDART00000166397.2 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL928808.1)

HSP 1 Score: 224.942 bits (572), Expect = 5.306e-65
Identity = 133/344 (38.66%), Postives = 186/344 (54.07%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLT--GEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTL---FQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSL----ELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFHC 1088
            KRK  DE R F  EW   YFF E  GKPFCLIC  S++  K  N++RH+   H    ++     E+RK+K +TLK     Q  +FRK S H+E V  +SY +A  +A+ ++P+ + EFVK+CL      LCPE + L    +D+ LS  T  +R+ +I  ++   L    +    +S+A+DES D+ D  Q  IF+R +  D  + EEL  +  LK  T G DL    KETL ++     L   KL  + TDG   M GS+ G+VG   A+ +  A      FHCIIHQE      L ++  IM  V+  VN++R H L HRQFK  + E+D +L     LFHC
Sbjct:   10 KRKYEDERRTFLSEWEDLYFFVERNGKPFCLICQTSLSHFKASNLERHFTSLHSAVAREFPKGSELRKHKVKTLKGQAEKQTQLFRKFSKHSETVTLASYQLAWNIARAKKPYLEGEFVKKCLSDAVAILCPENENLKRSVKDLQLSRHTVEQRISDIDNSVETHLLSDLQKCQYFSIALDESCDVQDKPQFAIFVRFVSEDCTIREELLDIVPLKDRTRGIDL----KETLMTVVEKANLQLSKLTAIVTDGAPAMLGSERGLVGLCKADDRFPAF---WTFHCIIHQEHWVSKKL-NLDHIMKPVLEIVNFVRTHALNHRQFKNLIDELDEDLPSDL-LFHC 344
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Zebrafish
Match: CR392001.3 (pep chromosome:GRCz11:8:38963323:38965260:-1 gene:ENSDARG00000117159.1 transcript:ENSDART00000181495.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:CR392001.3)

HSP 1 Score: 163.31 bits (412), Expect = 1.125e-42
Identity = 118/344 (34.30%), Postives = 168/344 (48.84%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTENG-GKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLT-GEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTL------FQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCC-TILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFH 1085
            +KRKI +E R FN  W   + F  N  G P CL+C + ++  K+ NV+RH++  H     +   G  RK+    L   L  +++ F+K          +S++    + K  +PFTD +++K   + ++E L  + K         +D+ LSA+T   R  ++  N+ EQ      S   YS+A DES    DTA L  ++   DG     EE+  L  LKG T G D+   V + LN   +    L  V TDG  +M GSK G V      LQ     N + FHCI+HQE+LC  T  S    +MN VI  VN I    L HRQF+  L E+DSE  Y+  L H
Sbjct:    6 KKRKITEENRGFNVSWTESFAFVANAEGLPECLLCSEKLSNNKKSNVERHFQGRHATFAAEYPVGSERKSAIALLVEKLEERKNKFKKWIASPNSTTAASFVATREIIKRGKPFTDGDYMKESFINISEHLFSDFKNKTEIIQKIKDMPLSAKTVKERAIKMAGNITEQQIKDINSAPAYSIACDES---CDTALLCRYVNS-DGP---QEEIIKLIPLKGQTRGEDICEAVLKCLNENGINTNHLISVATDGAPSMRGSKRGFVTL----LQKALDRNLLAFHCILHQEALCAQTFPSECMVVMNLVIEMVNKIIAKALNHRQFRALLDEVDSE--YSDLLLH 336
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Zebrafish
Match: traf3 (TNF receptor-associated factor 3 [Source:ZFIN;Acc:ZDB-GENE-040801-257])

HSP 1 Score: 67.0106 bits (162), Expect = 3.032e-11
Identity = 45/166 (27.11%), Postives = 80/166 (48.19%), Query Frame = -1 
Query: 1238 MEDLRMEIKSLKNEIIELKRNYQNQEEKKDLLIMKKAPDEIYKQNADSVMRLNDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQ------ERVKHIYSNPFYSVKFGYKMCLSAYF----LKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELIN 1705
            +E LR  ++S+++ +  L  +  N       L    A  E      D +M ++D        + L +++ K+  +E  +  G L WKI++  ++       +   +YS PFY+  FGYKMC   Y     +     + ++F ++RGE+D  L WPFK  VT+ L++
Sbjct:  352 VETLRGSVESMRSMVSSLDSSCVNSASGSHTL----ASLEQQLTRHDDLMSVHD--------VRLAEMDLKLQVLETASFNGTLIWKIRDYKRRKQEAVVSKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVVMRGEYDALLQWPFKQKVTLMLMD 505
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Zebrafish
Match: traf5 (Tnf receptor-associated factor 5 [Source:ZFIN;Acc:ZDB-GENE-071120-3])

HSP 1 Score: 60.4622 bits (145), Expect = 9.919e-10
Identity = 45/173 (26.01%), Postives = 93/173 (53.76%), Query Frame = -1 
Query: 1238 MEDLRMEIKSLKNEIIELKRNYQNQEEKKDLLIMKKAPDEIYKQNADSVMRLNDHNVKLKQI---------INLPKLN---KKVDKIENENIFGQLEWKIQNV-SQQERVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIG----IYFHLLRGEFDDNLVWPFKYVVTIELIN 1705
            +E+ R+ I S++ E+ +L+      E K++L  ++ + D + +Q A     L +H   L+Q          I++ +L    +++ ++E+ +  G+L WK+++   ++E    + S+PFY+ + GYK+ + AY        G    +Y  ++RG+FD  L WPF+  +T+ L++
Sbjct:   21 VEEQRVRICSVQRELRDLR--VLGSELKEELPRLQASLDSLRQQVA-VTESLREHLGALEQTCERHTRLLDIHVEQLQCNEQRLRQLESSSYDGKLIWKVRDYWHRKESGAALSSSPFYTSRSGYKLSVRAYLGGDGSGRGSHMSLYITIMRGDFDSFLPWPFRQNITLTLLD 190
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Zebrafish
Match: BX901915.1 (pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:28768979:-1 gene:ENSDARG00000109857.1 transcript:ENSDART00000191629.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:BX901915.1)

HSP 1 Score: 58.5362 bits (140), Expect = 4.786e-9
Identity = 47/194 (24.23%), Postives = 92/194 (47.42%), Query Frame = -1 
Query: 1229 LMNMMEDLRMEIKSLKNEIIELKRNYQ----------------NQEEKKDLLIMKKAPDEIYKQNADSVMRLNDHNVKLKQIINLPKLN-----KKVDKIENENIFGQLEWKIQNVSQQE------RVKHIYSNPFYSVKFGYKMCLSAYF----LKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKN 1717
            L++ +  +++ ++SL+ +++EL R  Q                N+E ++    M+ A +  ++ + D +  LN+   +L++ + L  L+      K+ ++      G   WKI + S++       R   ++S  FY+ K+GYKMCL  Y           + ++F ++RG  D  L WPF   VT+ L++  N
Sbjct:   21 LLHFIMGIKVNLESLQPQMVELSRRCQELELKVNTFENIVCVLNREMERSATTME-AYNRQHRLDQDKIEILNNKVRQLERTVGLRDLSIVEMEAKMREMSAATYDGVFVWKISDFSKKRQDAVAGRAPAMFSPAFYTSKYGYKMCLRIYLNGDGTGRGTHLSLFFVVMRGHSDALLKWPFNQKVTLMLLDQNN 213
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Xenopus
Match: spag1 (sperm associated antigen 1 [Source:Xenbase;Acc:XB-GENE-853609])

HSP 1 Score: 250.366 bits (638), Expect = 1.002e-74
Identity = 141/335 (42.09%), Postives = 200/335 (59.70%), Query Frame = 3 
Query:   63 FTKMSSRKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPET--KTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIR--RHGLKHRQFKEFLKEIDS 1055
            FTK  ++KRKI  E R F E+W  +YFF +N  KP CL+C ++++  KEYNVKRHY   H  +Y   TGE R    + LK+ L  Q++IF   +   +  V +S++VAE +AK + PF+    VK C + +AE    ET  KT+ + ISLS +T AR +  I  +L ++L+   +S   +S+A+DES DITDT QL+IF+R +D +F++ EEL  +  L G+T G D++  VK T+     G+    C+ TDG R M G   G+ GR+  E   I C    +FHCI+HQE LC T L  M DIM+ V    N IR     L HR+FK FL+E+D+
Sbjct:   10 FTKNCAKKRKIDSENREFQEKWEEEYFFGKNKDKPQCLVCAQTISSCKEYNVKRHYTTLHGAKYAKYTGEARLTIIKDLKSKLCKQKNIFSAVTTTQKAAVKASFLVAEEIAKRKYPFSSGTLVKTCALKMAEAFGNETMAKTV-ESISLSHQTVARHICTINQHLTDKLQNILRSAPYFSIALDESTDITDTCQLVIFVRSVDQEFHISEELLEIVPLHGSTKGEDIYNAVKATVTKYG-GFSSCTCIVTDGARAMVGRNQGLAGRLRKE--GIDCH---MFHCIVHQEVLCGTSL-KMADIMDVVTKVTNLIRGGNRSLTHRRFKNFLEELDA 336
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000016563.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:4:37379994:37381838:-1 gene:ENSXETG00000009412.1 transcript:ENSXETT00000016563.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 250.751 bits (639), Expect = 1.426e-74
Identity = 141/335 (42.09%), Postives = 200/335 (59.70%), Query Frame = 3 
Query:   63 FTKMSSRKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPET--KTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIR--RHGLKHRQFKEFLKEIDS 1055
            FTK  ++KRKI  E R F E+W  +YFF +N  KP CL+C ++++  KEYNVKRHY   H  +Y   TGE R    + LK+ L  Q++IF   +   +  V +S++VAE +AK + PF+    VK C + +AE    ET  KT+ + ISLS +T AR +  I  +L ++L+   +S   +S+A+DES DITDT QL+IF+R +D +F++ EEL  +  L G+T G D++  VK T+     G+    C+ TDG R M G   G+ GR+  E   I C    +FHCI+HQE LC T L  M DIM+ V    N IR     L HR+FK FL+E+D+
Sbjct:   10 FTKNCAKKRKIDSENREFQEKWEEEYFFGKNKDKPQCLVCAQTISSCKEYNVKRHYTTLHGAKYAKYTGEARLTIIKDLKSKLCKQKNIFSAVTTTQKAAVKASFLVAEEIAKRKYPFSSGTLVKTCALKMAEAFGNETMAKTV-ESISLSHQTVARHICTINQHLTDKLQNILRSAPYFSIALDESTDITDTCQLVIFVRSVDQEFHISEELLEIVPLHGSTKGEDIYNAVKATVTKYG-GFSSCTCIVTDGARAMVGRNQGLAGRLRKE--GIDCH---MFHCIVHQEVLCGTSL-KMADIMDVVTKVTNLIRGGNRSLTHRRFKNFLEELDA 336
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000028445.1 (general transcription factor II-I repeat domain-containing protein 2-like [Source:NCBI gene;Acc:101734469])

HSP 1 Score: 179.104 bits (453), Expect = 2.841e-48
Identity = 116/336 (34.52%), Postives = 175/336 (52.08%), Query Frame = 3 
Query:   72 MSSRK-RKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLC-PETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLEL-GWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRH-----GLKHRQFKEFLKEIDS 1055
            MS+ K RK+  E R F E W   YFF +  GKP CL+C + +AV KEYNVKRHY   HE+ Y   TG+ R      L++ L  Q+++   ++  +   + +S+I+ E + K ++ F   + VK C V +A      E    F  ISL  +T ARRV  +   + ++L    K+   +SLA+DE+ D   T  L+IFIR ID  FN+ E++    SL       DL  + K +L  LE  G++K   V T+G ++M     G    + A L+    D  +V HCI+H+E L  T+L  M D+M  V+   N+I         +  ++FK FL E+ +
Sbjct:    1 MSAPKHRKVDSENRSFKERWELDYFFVKCNGKPLCLLCSQILAVCKEYNVKRHYISLHEKTYSQYTGDHRMAILNELRSKLNKQETVTSIETATDTAALKASFIICEEIVKRKQAFDSVDVVKECAVKMARVFGNEEMAAKFDSISLQPQTVARRVSAMHQQITQKLHAILKNCCYFSLALDETTDSCGTDLLVIFIRAIDDGFNISEDILKCVSLPKTAKEEDLLNEAKSSL--LEYGGFDKCTSVMTNGSKSMTAKSLG----LSALLRKEGAD-CVVLHCIMHEEMLIGTLL-KMSDVMEVVVKISNFILEKRGFITAVTKKKFKTFLDELSA 328
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000010836.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:7:63865670:63866962:-1 gene:ENSXETG00000001503.1 transcript:ENSXETT00000010836.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.2478 bits (173), Expect = 1.539e-13
Identity = 45/118 (38.14%), Postives = 70/118 (59.32%), Query Frame = 3 
Query:  135 KYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYK---DLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVA-EKLCPE 476
            KYFFT    K  C+I H  VA+ K+ NV+ H+   H R+Y     +   + K K + LK+ L+AQQ+IF+K +  ++    +S+ VA ++AK+++P+ D E VK  +VAV    L PE
Sbjct:   12 KYFFTNFREKCICIIYHAPVAIGKKCNVESHFTTMH-RKYDVEFPVGTNLWKVKVKELKSVLSAQQAIFKKPANKSKAATIASFKVAHVLAKKKKPYEDGEIVKDAMVAVRFHYLLPE 128
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Xenopus
Match: ssh2 (slingshot protein phosphatase 2 [Source:Xenbase;Acc:XB-GENE-993093])

HSP 1 Score: 64.3142 bits (155), Expect = 2.842e-10
Identity = 52/176 (29.55%), Postives = 89/176 (50.57%), Query Frame = -1 
Query: 1238 MEDLRMEIKSLK---NEIIELKRNYQNQEEKKDLLIMKKAPDEIYKQNADS------VMRLNDHNVKLK-QIINLPKLNKKVDKIENENIFGQLEWKIQNVSQ--QERVK----HIYSNPFYSVKFGYKMCLSAYF----LKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELIN 1705
            ++DL  EI++L+   +E   +K NY++ + +   L       E+  +NA S        ++N H+  L    I L  ++ +   +E  +  G L WKI++  +  QE V      +YS PFY+  FGYKMC   Y     +     + ++F ++RGE+D  L WPFK  V++ L++
Sbjct:  300 LKDLDKEIRNLRQTGDEADGMKSNYESLQNRLSQL-------EVMAKNAASWNPGVLETQINRHDQMLSVHDIRLADMDLRFQVLETASYNGVLIWKIRDYKRRKQEAVMGKTLSLYSQPFYTGYFGYKMCARVYLNGDGMGKGTHLSLFFVIMRGEYDALLPWPFKQKVSLMLMD 468
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Mouse
Match: Gtf2ird2 (GTF2I repeat domain containing 2 [Source:MGI Symbol;Acc:MGI:2149780])

HSP 1 Score: 210.305 bits (534), Expect = 5.352e-58
Identity = 120/336 (35.71%), Postives = 173/336 (51.49%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNI--ACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFH 1085
            KRKI  EGRVF E+W   YFF E    P CLIC +SV+V KEYN++RHY+  H R Y   +G+ R+ K R LK  L                                         ++ L+  +E +CPE    F + S    +  +  EE+  +L+E+L+ K +SF  YS+A+DE  DI DT QL IFIRG+D +F+V EEL     + GA +GN++F++V+++L    + W KL  V + G   M  + +G+V ++ A   +     D   V  CIIH E LC   L  M  +M+ V+ +VN+I   GL H  F   L E+DS+  Y   L+H
Sbjct:  414 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSVSVSKEYNLRRHYQTNHSRHYDQYSGQAREEKLRELKRGL-----------------------------------------RKYLLGASEIVCPEQP--FPNASPPTNSAVQPAEEVAGSLWEKLRQKIRSFVAYSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAMMDANSGLVTKLRARAASCCKGADLKSV-RCIIHPEWLCAQKL-RMGHVMDVVVDSVNWICSRGLNHGDFTTLLYELDSQ--YGSLLYH 702
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Mouse
Match: Epm2aip1 (EPM2A (laforin) interacting protein 1 [Source:MGI Symbol;Acc:MGI:1925031])

HSP 1 Score: 132.88 bits (333), Expect = 2.183e-32
Identity = 87/328 (26.52%), Postives = 155/328 (47.26%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTE--NGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            R R   DE  VF  EW  +Y   E   G    CL+C + VA  +E +V+RHYE EHE   + +  E R      L+    +  ++   +    E    +   +   +A + R + + +FV +C+  +  ++ P+   + + I LS     +R+  I +NL  QL  +A+ F  YSLA+D+   +     L++FIRG+  D  V E+L ++ +L    +   L   + E L +  L  +++  +TT     M G  +G+V  +  +  +  C N + +   +H E L  +    +  I+NT+   V  I+  G++  +F+  L E +SE
Sbjct:    7 RIRMEVDEALVFRPEWTQRYLVVEPAEGDGALCLVCRRLVASTRERDVRRHYEAEHEFYERFVGDEERAALVERLRQGDMSLAAVLTPE----ERATRAGLGLCRFLALKGRGWGEGDFVHQCMEVLLREVLPDHVGVLEGIDLSPEITRQRILSIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLE-LLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQPLLTESESE 329
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Mouse
Match: Epm2aip1 (EPM2A (laforin) interacting protein 1 [Source:MGI Symbol;Acc:MGI:1925031])

HSP 1 Score: 132.88 bits (333), Expect = 2.183e-32
Identity = 87/328 (26.52%), Postives = 155/328 (47.26%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTE--NGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            R R   DE  VF  EW  +Y   E   G    CL+C + VA  +E +V+RHYE EHE   + +  E R      L+    +  ++   +    E    +   +   +A + R + + +FV +C+  +  ++ P+   + + I LS     +R+  I +NL  QL  +A+ F  YSLA+D+   +     L++FIRG+  D  V E+L ++ +L    +   L   + E L +  L  +++  +TT     M G  +G+V  +  +  +  C N + +   +H E L  +    +  I+NT+   V  I+  G++  +F+  L E +SE
Sbjct:    7 RIRMEVDEALVFRPEWTQRYLVVEPAEGDGALCLVCRRLVASTRERDVRRHYEAEHEFYERFVGDEERAALVERLRQGDMSLAAVLTPE----ERATRAGLGLCRFLALKGRGWGEGDFVHQCMEVLLREVLPDHVGVLEGIDLSPEITRQRILSIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLE-LLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQPLLTESESE 329
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Mouse
Match: Zbed5 (zinc finger, BED type containing 5 [Source:MGI Symbol;Acc:MGI:1919220])

HSP 1 Score: 107.457 bits (267), Expect = 7.435e-24
Identity = 85/309 (27.51%), Postives = 148/309 (47.90%), Query Frame = 3 
Query:  162 KPFCLICHK--SVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLT-AQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEK-----LCPETKTLFQDISLSARTCARRVEEIGTNLFEQL--KCKAKSFDCYSLAMDESIDITDTAQLIIFIRGI-DGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCC-TILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEID 1052
            +P C+IC    S   MK   +KRH+E +H        G+   N FR+    L  A+     K +  N   V +SY+VA  +A++ +P T   F +  L  VA+      +  E  T    +SLS  T  RR+ ++  ++ +Q+  + K+      S+ +DES D+ +  QL++++R I DGDF   +E      L+   T  D+F  V   L   E+ W+ +  V TDG     G ++G    +  E         +  HC++H ++L   T+    +++M +V+S+VN+++   L  R F +   ++D
Sbjct:  188 RPQCVICGVVLSAESMKPNKLKRHFESKHS----SFAGK-DTNYFRSKADGLKKARPDTGSKSNKQNVAAVETSYLVALRIARDMKPHT---FAEHLLFPVAKDRVRVMIGDEFVTKLSAVSLSNDTVRRRIHDMSADILDQVVQEIKSAPLPICSIQLDESTDVANCLQLMVYVRYINDGDFK--DEFLCCKPLERTATALDVFEAVDSFLRQHEISWKSICGVCTDGAPATLGCQSGFQRLVLNE-----SPKAIGAHCMLHLQTLAMKTLPQDFQEVMKSVLSSVNFVKASSLNSRLFLQLCSDLD 481
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Mouse
Match: Med25 (mediator complex subunit 25 [Source:MGI Symbol;Acc:MGI:1922863])

HSP 1 Score: 87.4261 bits (215), Expect = 1.955e-17
Identity = 39/82 (47.56%), Postives = 52/82 (63.41%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSI 329
            KRK   EGRVF E+W   YFF E    P CLIC K+V+V+KEYN+KRHYE +H + Y   T + R    + LK +L A +++
Sbjct:  716 KRKREGEGRVFREKWERDYFFVEVKSMPTCLICKKNVSVLKEYNLKRHYESQHSKSYDQYTAQSRDTLLQELKRALRASEAL 797
[Close]
BLAST of DUF4371 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q99NI3|GT2D2_MOUSE (General transcription factor II-I repeat domain-containing protein 2 OS=Mus musculus OX=10090 GN=Gtf2ird2 PE=2 SV=1)

HSP 1 Score: 210.305 bits (534), Expect = 3.744e-57
Identity = 120/336 (35.71%), Postives = 173/336 (51.49%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNI--ACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFH 1085
            KRKI  EGRVF E+W   YFF E    P CLIC +SV+V KEYN++RHY+  H R Y   +G+ R+ K R LK  L                                         ++ L+  +E +CPE    F + S    +  +  EE+  +L+E+L+ K +SF  YS+A+DE  DI DT QL IFIRG+D +F+V EEL     + GA +GN++F++V+++L    + W KL  V + G   M  + +G+V ++ A   +     D   V  CIIH E LC   L  M  +M+ V+ +VN+I   GL H  F   L E+DS+  Y   L+H
Sbjct:  414 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSVSVSKEYNLRRHYQTNHSRHYDQYSGQAREEKLRELKRGL-----------------------------------------RKYLLGASEIVCPEQP--FPNASPPTNSAVQPAEEVAGSLWEKLRQKIRSFVAYSIAIDEITDINDTTQLAIFIRGVDDNFDVSEELLDTVPMTGAKSGNEIFLRVEKSLKKFSIDWSKLVSVASTGTPAMMDANSGLVTKLRARAASCCKGADLKSV-RCIIHPEWLCAQKL-RMGHVMDVVVDSVNWICSRGLNHGDFTTLLYELDSQ--YGSLLYH 702
[Close]
BLAST of DUF4371 domain-containing protein vs. UniProt/SwissProt
Match: sp|A4IFA3|GT2D2_BOVIN (General transcription factor II-I repeat domain-containing protein 2 OS=Bos taurus OX=9913 GN=GTF2IRD2 PE=2 SV=1)

HSP 1 Score: 206.068 bits (523), Expect = 1.268e-55
Identity = 114/334 (34.13%), Postives = 175/334 (52.40%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPM-VFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEID----SELFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y   T ++R  K + LK  L                                         ++ L+  ++ +CPE K +F  ++       + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F++V+++L    + W KL  V + G   M  +  G+V ++ +++  +   + +    CIIH ESLC   L  M  IM+ V++ VN+I   GL H +F   L E+D    S L+YT
Sbjct:  419 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTEKMRDEKLQELKEGL-----------------------------------------RKYLLGSSDTVCPEQKQVFAKVNPRENAAVQPVEDVAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFNIDWSKLVSVASTGTPAMVDANDGLVTKLKSKVAMVCKGSDLKSVCCIIHPESLCAQKL-KMDHIMSVVVNAVNWICSRGLNHSEFTTLLYELDCQYGSLLYYT 710
[Close]
BLAST of DUF4371 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6EKJ0|GTD2B_HUMAN (General transcription factor II-I repeat domain-containing protein 2B OS=Homo sapiens OX=9606 GN=GTF2IRD2B PE=1 SV=1)

HSP 1 Score: 205.682 bits (522), Expect = 1.667e-55
Identity = 117/342 (34.21%), Postives = 176/342 (51.46%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRI---------CAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y   T  +R  K   LK  L                                         ++ L+  ++  CPE K +F + S + ++  + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F++V+++L    + W +L  V + G   M  +  G+V ++          AEL++I         CIIH ESLC   L  M  +M+ V+ +VN+I   GL H +F   L E+DS+    L+YT
Sbjct:  418 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGL-----------------------------------------RKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSIC--------CIIHPESLCAQKL-KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYT 709
[Close]
BLAST of DUF4371 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q86UP8|GTD2A_HUMAN (General transcription factor II-I repeat domain-containing protein 2A OS=Homo sapiens OX=9606 GN=GTF2IRD2 PE=1 SV=3)

HSP 1 Score: 202.986 bits (515), Expect = 1.492e-54
Identity = 117/342 (34.21%), Postives = 175/342 (51.17%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRI---------CAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  EGRVF E+W   YFF E    P CLIC +S++V KEYN++RHY+  H + Y      +R  K   LK  L                                         ++ L+  ++  CPE K +F + S + ++  + VE++  NL+E+L+ K +SF  YS+A+DE  DI +T QL IFIRG+D +F+V EEL     + G  +GN++F +V+++L +  + W KL  V + G   M  +  G+V ++          AEL++I         CIIH ESLC   L  M  +M+ V+ +VN+I   GL H +F   L E+DS+    L+YT
Sbjct:  418 KRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMERMRDEKLHELKKGL-----------------------------------------RKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLKNFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSIC--------CIIHPESLCAQKL-KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYT 709
[Close]
BLAST of DUF4371 domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8VEH5|EPMIP_MOUSE (EPM2A-interacting protein 1 OS=Mus musculus OX=10090 GN=Epm2aip1 PE=1 SV=1)

HSP 1 Score: 132.88 bits (333), Expect = 1.527e-31
Identity = 87/328 (26.52%), Postives = 155/328 (47.26%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTE--NGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            R R   DE  VF  EW  +Y   E   G    CL+C + VA  +E +V+RHYE EHE   + +  E R      L+    +  ++   +    E    +   +   +A + R + + +FV +C+  +  ++ P+   + + I LS     +R+  I +NL  QL  +A+ F  YSLA+D+   +     L++FIRG+  D  V E+L ++ +L    +   L   + E L +  L  +++  +TT     M G  +G+V  +  +  +  C N + +   +H E L  +    +  I+NT+   V  I+  G++  +F+  L E +SE
Sbjct:    7 RIRMEVDEALVFRPEWTQRYLVVEPAEGDGALCLVCRRLVASTRERDVRRHYEAEHEFYERFVGDEERAALVERLRQGDMSLAAVLTPE----ERATRAGLGLCRFLALKGRGWGEGDFVHQCMEVLLREVLPDHVGVLEGIDLSPEITRQRILSIDSNLRSQLFNRARDFKAYSLALDDQAFVAYENYLLVFIRGVGRDLEVQEDLLTIINLTHHFSVGALMSAILEALQTAGLSLQRMVGLTTTHTLRMIGENSGLVSYMREKAVSPNCWNVIHYSGFLHLE-LLSSYDVDINQIINTISEWVVMIKTRGVRRPEFQPLLTESESE 329
[Close]
BLAST of DUF4371 domain-containing protein vs. TrEMBL
Match: A0A2S2PAF3 (General transcription factor II-I repeat domain-containing protein 2 OS=Schizaphis graminum OX=13262 GN=GTF2IRD2_3 PE=4 SV=1)

HSP 1 Score: 399.053 bits (1024), Expect = 4.149e-129
Identity = 181/327 (55.35%), Postives = 252/327 (77.06%), Query Frame = 3 
Query:   78 SRKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            + KRKI DE R+F E+W   +FF E+GGK  CLIC+K++ VMKEYNV+RHY+ EH+ ++++LTGE+R+NK +    SL++QQ+IF+ Q+  NE  V +SY+VAE++AK  RPFTD EF K+C++AV  ++CPE   LF++ISLS RTC RR EE+G NLF QLK    S DC+S+A+DES DI+DTAQL+IFIRGID +FN++EELA +CS+KG TTG D+F  ++ +   L L  +KL  +TTDGG+NM G   G VGRI  ++ +   + PMVFHCIIHQE+LCC ++ + K++M+TVIST+NYIR++GL HRQF++FL+EI++E
Sbjct:    2 APKRKINDEHRIFKEDWTELFFFIEHGGKLLCLICNKTITVMKEYNVRRHYDNEHKAKFENLTGELRQNKIKHFLTSLSSQQNIFKSQNTRNEASVRASYVVAEMLAKNNRPFTDIEFFKKCMLAVTNEVCPEKIKLFEEISLSTRTCVRRTEELGNNLFSQLKDIIPSLDCFSIAIDESTDISDTAQLLIFIRGIDKEFNIYEELADMCSIKGTTTGEDIFKNIENSFEKLGLSLKKLISITTDGGKNMSGIHKGFVGRIKTKMIDNKFEMPMVFHCIIHQEALCCKVM-AWKNVMDTVISTINYIRKNGLAHRQFQQFLEEIEAE 327
[Close]
BLAST of DUF4371 domain-containing protein vs. TrEMBL
Match: A0A2J7QYZ4 (DUF4371 domain-containing protein OS=Cryptotermes secundus OX=105785 GN=B7P43_G10009 PE=4 SV=1)

HSP 1 Score: 349.362 bits (895), Expect = 1.981e-110
Identity = 169/326 (51.84%), Postives = 222/326 (68.10%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            +KRK+  E R F  EW+  YF TE  GK  CL+C  ++AV+KEYN++RHY+ +H  QY  LTG+ R  K  TLK S++ Q+S F K    N+     S  VA L+AKE  PFTD E +K CL+   E++CPE   LF +ISLSART ARRVE+IG+N+  QL  KA  F+ +SLA+DES DITDTAQL++FIRG++ DF V EELAS+ SL+G TTG D+F +V+E L    L W +LKCVTTDGG+NM G+  G+VG I    +N  C  PMV H IIHQ  LC   L ++  ++  V+STVN+IR  GL HRQF++FL E+++E
Sbjct:    8 KKRKVDLECRAFKAEWSENYFVTELDGKALCLLCSDTIAVLKEYNIRRHYQTKHSAQYSQLTGKERSQKLETLKRSISLQRSFFTKMKNENKAASKVSLRVAHLLAKEGNPFTDGELIKSCLIVAVEEMCPEKMDLFNNISLSARTVARRVEDIGSNITNQLINKANDFEWFSLALDESTDITDTAQLLLFIRGVNADFEVTEELASMNSLRGTTTGEDIFKEVEEMLTKYNLKWNQLKCVTTDGGKNMSGTGKGLVGSIYTACENARCTRPMVIHYIIHQHVLCGKYL-NLSCVLEPVVSTVNFIRSRGLNHRQFRDFLSEVEAE 332
[Close]
BLAST of DUF4371 domain-containing protein vs. TrEMBL
Match: A0A2J7QG63 (DUF4371 domain-containing protein OS=Cryptotermes secundus OX=105785 GN=B7P43_G02264 PE=4 SV=1)

HSP 1 Score: 347.051 bits (889), Expect = 4.346e-108
Identity = 167/326 (51.23%), Postives = 221/326 (67.79%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            +KRK   E R +  EW+  YF TE  GK  CL+C  ++AV+KEYN++RHY+ +H  QY  LTG+ R  K  TLK +++ Q+S F K    N+     S  VA L+AKE +PFTD E +K CL+   E++CPE   LF +ISLS RT ARRVE IG+N+  QL  KA  F+ +SLA+DES DITDTAQL++FIRG++ DF V EELAS+ SL+G TTG D+F +V+E L    L W +LKCVTTDGG+NM G+  G+VG I    +N  C  PMV HCIIHQ  LC   L ++  ++  V+STVN+IR  GL HRQF++FL E+++E
Sbjct:    8 KKRKADLECRAYKAEWSENYFVTELDGKALCLLCSDTIAVLKEYNIRRHYQTKHSAQYSQLTGKERSQKLETLKWTISLQRSFFTKIKNENKAASKVSLRVAHLLAKEGKPFTDGELIKSCLIVAVEEMCPEKMDLFNNISLSTRTVARRVENIGSNITNQLINKANDFEWFSLALDESTDITDTAQLLLFIRGVNADFEVTEELASMNSLRGTTTGEDIFKEVEEMLTKYNLKWNQLKCVTTDGGKNMSGTGKGLVGSIYTACENARCTRPMVIHCIIHQHVLCGKYL-NLSCVLEPVVSTVNFIRSRGLNHRQFRDFLSEVEAE 332
[Close]
BLAST of DUF4371 domain-containing protein vs. TrEMBL
Match: A0A2J7RR13 (DUF4371 domain-containing protein OS=Cryptotermes secundus OX=105785 GN=B7P43_G14697 PE=4 SV=1)

HSP 1 Score: 344.354 bits (882), Expect = 5.632e-107
Identity = 167/325 (51.38%), Postives = 221/325 (68.00%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            KRK+  E R F  EW+  YF TE  GK  CL+C  ++AV+KEYN++RHY+ +H  QY  LTG+ R  K  TLK S++ Q+S F K    N+     S  VA L+AKE +PFTD E +K CL+   E++CPE   LF +ISLSART ARRVE+IG+N+  QL  KA  F+ +SLA+DES DITDTAQL++FIRG++ DF V EELAS+ SL+G TTG D+F +V+E L    L   +LKCVTTDGG+NM G+  G+VG I    +N  C  PMV HCIIHQ  LC   L ++  ++  V+STVN+IR  GL HRQF++F  ++++E
Sbjct:   26 KRKVDLECRAFKAEWSENYFVTELDGKALCLLCSDTIAVLKEYNIRRHYQTKHSAQYSQLTGKERSQKLETLKRSISLQRSFFTKMKNENKAASKVSLRVAHLLAKEGKPFTDGELIKSCLIVAVEEMCPEKMNLFNNISLSARTVARRVEDIGSNITNQLINKANDFEWFSLALDESTDITDTAQLLLFIRGVNADFEVTEELASMNSLRGTTTGEDIFKEVEEILTKYNLKSNQLKCVTTDGGKNMSGTGKGLVGSIYTACENARCTRPMVIHCIIHQHVLCGKYL-NLSCVLEPVVSTVNFIRSRGLNHRQFRDFPSKVEAE 349
[Close]
BLAST of DUF4371 domain-containing protein vs. TrEMBL
Match: I3KZR5 (Uncharacterized protein OS=Oreochromis niloticus OX=8128 PE=4 SV=1)

HSP 1 Score: 340.117 bits (871), Expect = 3.723e-106
Identity = 165/333 (49.55%), Postives = 229/333 (68.77%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI  E RVFN +W   YFF +   K  CLIC ++VAV KEYN++RHYE  H+ +Y  L G++R +K   LK+ L AQQ+ F +Q+  N+  V +S+ VA+L+A   +PFT+ EFVK+CL  V E++CP+ K +F  +SLSA T  RRVEEIG N++ QL+ K K FD +SLA+DES D+ DTAQL+IFIRG+  +F + EELA+L SLKG TTG D+F KV +T+  L+L W KL  +TTDG   M G+  G++GR+  E++      P+  HCIIHQ++LCC +L     +M  V+S +N+IR +GLKHRQF++FL E++S     L+YT
Sbjct:    7 KRKIDSECRVFNLQWTHDYFFVQCKEKAVCLICQETVAVFKEYNLRRHYECRHKDKYDSLQGQMRTDKISKLKSGLLAQQTAFVRQTQLNQSSVRASFRVAQLIASYGKPFTEGEFVKKCLNVVVEEVCPDKKDVFNAVSLSASTITRRVEEIGGNVYAQLQQKTKEFDFFSLALDESTDVQDTAQLLIFIRGVSANFEMCEELAALQSLKGTTTGEDIFDKVCQTMKELDLDWAKLASITTDGAPCMVGASRGLIGRMNREMEERGLTAPLQVHCIIHQQALCCKVL-KWDSVMKAVVSCINFIRANGLKHRQFQQFLSELESAYGDVLYYT 338
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000035253.1 (general transcription factor II-I repeat domain-containing protein 2B-like [Source:NCBI gene;Acc:111191579])

HSP 1 Score: 299.286 bits (765), Expect = 2.636e-93
Identity = 142/328 (43.29%), Postives = 220/328 (67.07%), Query Frame = 3 
Query:   78 SRKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMV-FHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            SRKRK+  +GR+F + W  +Y F   G +P CL+C ++V+V+KEYN++RH++ +H  +Y   + + ++   + LK  L +QQ++F K +  N   V +S+IVAE +A+  + F+   F+K+C++ V E++CP+    F+++SLS  T A RV+E+  NL  QL  + +S+  +SLA+DES D TDTAQL IFIRG+  D +V E+L  + ++ G TTG D+F  V+++++   L WE L  +TTDG   MCG K G+VG +  ++Q + C  P++ +HCIIHQE+LC  +L  M +I+ TV+ TVN+IR  GL HRQF+ FL+EIDSE
Sbjct:    2 SRKRKVDADGRLFQQRWEGEYMFVLQGERPVCLLCCEAVSVIKEYNLRRHFDTKHGAKYGKASLQEKQQIAQELKDKLKSQQNLFTKATAKNSAAVKASFIVAEEIARASKYFSGGAFLKQCMLKVCEQVCPDQIQTFKNVSLSRNTIADRVKELAENLATQLAEETRSYTAFSLAVDESTDNTDTAQLAIFIRGVKSDLSVTEDLLDVAAMHGTTTGQDIFDAVEKSVSKNALAWENLVGLTTDGAPAMCGEKNGLVGLMKGKMQKMNCHMPLITYHCIIHQEALCGKVL-GMDNIVTTVMKTVNFIRARGLNHRQFQMFLQEIDSE 328
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000030525.1 (pep primary_assembly:Astyanax_mexicanus-2.0:1:12992682:12994541:1 gene:ENSAMXG00000035573.1 transcript:ENSAMXT00000030525.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 288.115 bits (736), Expect = 7.400e-89
Identity = 141/333 (42.34%), Postives = 211/333 (63.36%), Query Frame = 3 
Query:   84 KRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE----LFYT 1070
            KRKI DE R F E+W  ++FF E+ G P CLIC + VAV KEYN+KRHY   H  +Y    G+ R N+   LK  L  QQ  F+K +  N+  V +SY+V+E++AK  +PFT+ EFVK+C++  A  +CPE K  F +ISLSA T A R+ ++ +++++QL  KAK F  YS+A+DES DITDTAQL I++RG+D +F V EEL ++  + G TT  ++F ++ + + +  L W++   +TTDG  +M G K G        L+  + +  +  HCIIHQ++LC   L    ++M+ V+  +N IR   LKHR+F+  L+E++SE    L++T
Sbjct:   61 KRKICDEHRQFQEKWEVQFFFVEHRGIPTCLICTEKVAVHKEYNLKRHYTTRHAEEYAKYQGDERANRVANLKTCLLRQQDFFKKATKENDAAVEASYVVSEMIAKAGKPFTEGEFVKKCILQAASIVCPEKKGQFSNISLSANTVAERISDLSSDIYDQLCEKAKRFSVYSVALDESTDITDTAQLAIYVRGVDDNFEVTEELLTVIPMHGQTTAQEIFHQLCDAIENAGLPWKRFVGITTDGAPSMTGRKNG--------LEEESVEEAIALHCIIHQQALCSKCL-KFDNVMSVVVKCINQIRSRSLKHRRFRALLEEMESEYGDVLYFT 384
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000052542.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000549.1:35642:40620:1 gene:ENSAMXG00000033785.1 transcript:ENSAMXT00000052542.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 281.182 bits (718), Expect = 2.008e-87
Identity = 149/328 (45.43%), Postives = 200/328 (60.98%), Query Frame = 3 
Query:   75 SSRKRKIADEGRVFNEEWNSKYFFTENGGKPF-CLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDS 1055
            +S+KRK+  E R FN EW SKYFF E     F CL+C + VAV KEYN++RHYE +H +   DL GE RK K   LK  L +QQ +F K+   +E    +SY +A LVAK  RPF D EFVK C++   + +CPE K  F++ISLS  T  RR+ ++ +N + QL+ +      +S A+DES D TDTAQL IFIRG+ G   V++ELA+L  L G TTG ++F   K  + +L L W KL  VTTDG  +M G   G +G +   L          +HCIIHQE+LC   L   K IM+ V+S VN+IR   L HR+F+ FL++I +
Sbjct:    3 TSKKRKVDLEHRKFNPEWTSKYFFYETSSAVFSCLVCLECVAVAKEYNLRRHYETKHPK-LADLQGEDRKQKIEALKKQLVSQQGVFEKRRKESEACTIASYRIANLVAKSARPFIDGEFVKDCMLEACDVICPEAKDAFKNISLSRTTIQRRIVDLSSNSYCQLQSRINDVTYFSAALDESTDNTDTAQLSIFIRGVTGTCQVYQELAALVPLYGRTTGFEIFNAFKTAVENLNLPWSKLSAVTTDGAPSMVGETNGFIGHLKRHLGPDQAAELKHYHCIIHQEALCGKHL-QFKQIMDFVVSAVNFIRARSLNHREFQSFLEDISA 328
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000037725.1 (pep primary_assembly:Astyanax_mexicanus-2.0:14:29162452:29166863:1 gene:ENSAMXG00000037303.1 transcript:ENSAMXT00000037725.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 251.521 bits (641), Expect = 1.225e-73
Identity = 141/333 (42.34%), Postives = 194/333 (58.26%), Query Frame = 3 
Query:   63 FTKMSSRKRKIADEGRVFNEEWN-SKYFFTENGGKPF-CLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDS 1055
            FT    R   ++   R  +EE + S   F E     F CL+C + VAV KEYN++RHYE +H +   DL GE RK K   LK  L +QQ +F K+   +E    +SY +A LVAK  RPF D EFVK C++   + +CPE K  F++ISLS  T   R+ ++ +N + QL+ +      +S A+DES D TDTAQL IFIRG+ G   V++ELA+L  L G TTG ++F   K  + +L L W KL  VTTDG  ++ G   G +G +   L          +HCIIHQE+LC   L   K+IM+ V+S VN+IR   LKHR+F  FL++I +
Sbjct:  186 FTGAGVRSGLLSGITRQGDEETDASAVLFYETSSAVFSCLVCLECVAVAKEYNLRRHYETKHPK-LADLQGEDRKQKIEALKKQLVSQQGVFEKRRKESEACTIASYRIANLVAKSARPFIDGEFVKDCMLEACDVICPEAKDAFKNISLSRTTIQLRIVDLSSNSYCQLQSRINDVTYFSAALDESTDNTDTAQLSIFIRGVTGTCQVYQELAALVPLYGRTTGFEIFNAFKTAVENLNLPWSKLSAVTTDGALSVVGETNGFIGHLKRHLGPDQAAELKHYHCIIHQEALCGKHL-HFKEIMDFVVSAVNFIRARSLKHREFPSFLEDISA 516
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000036928.1 (pep primary_assembly:Astyanax_mexicanus-2.0:7:19677316:19680173:1 gene:ENSAMXG00000037520.1 transcript:ENSAMXT00000036928.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 228.409 bits (581), Expect = 2.974e-67
Identity = 129/296 (43.58%), Postives = 173/296 (58.45%), Query Frame = 3 
Query:  171 CLIC-HKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDS 1055
            CL C  K V++ KEYN++RHYE +H +   DL GE RK K   LK  L +QQ +F K+   +E    +SY +A LVAK   PF D EFVK C++   + +CPE K  F++ISLS  T  RR+         Q+K        +S A+DES D TDTAQL IFIRG+ G   V++ELA+L  L G TTG ++F   K  + +L L W KL  VTTDG  +M G   G +G +   L          +HCIIHQE+LC   L   K+IM+ V+S VN+IR   L HR+F+ FL++I +
Sbjct:    6 CLFCLSKHVSLKKEYNLRRHYETKHPK-LADLQGEDRKQKIEALKKQLVSQQGVFEKRRKESEACTIASYRIANLVAKSACPFIDGEFVKDCMLEACDVICPEAKDAFKNISLSRTTIQRRI---------QVKVTY-----FSAALDESTDNTDTAQLSIFIRGVTGTCQVYQELAALVPLYGRTTGFEIFNAFKTAVENLNLPWSKLSAVTTDGAPSMVGETNGFIGHLKRHLGPDQAAELKHYHCIIHQEALCGKHL-QFKEIMDFVVSAVNFIRARSLNHREFQYFLEDISA 285
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000074.1 (pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-1 gene:ENSPMAG00000000066.1 transcript:ENSPMAT00000000074.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 72.0182 bits (175), Expect = 1.287e-13
Identity = 44/168 (26.19%), Postives = 81/168 (48.21%), Query Frame = -1 
Query: 1238 EDLRMEIKSLKNEIIELKRNYQNQEEKKDLLIMKKAPDEIYKQNADSVMRLNDHNVKL-KQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQE------RVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIG------IYFHLLRGEFDDNLVWPFKYVVTIELIN 1702
            + LR ++      + EL       EE    +     P  +   ++     L+ H+ +L      L +++ +   +E  +  G+L WKI++ ++++      R   +YS PFY+  FGY+MC  AY     D +G      ++F ++RGE+D  L WPF+  VT+ L++
Sbjct:  248 DALRGDLDGTAATLHELGTRVAAIEESGGSVTHSSTPTRLAALDSA----LSRHDTQLFAHDTRLAEMDLRFQVLETASYNGKLVWKIRDYARRKQDAVSGRTLSLYSQPFYTSPFGYRMCARAYLNG--DGVGRGTHLSLFFVVMRGEYDALLPWPFRQRVTLTLLD 409
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002130.1 (pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 gene:ENSPMAG00000001936.1 transcript:ENSPMAT00000002130.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 68.9366 bits (167), Expect = 9.590e-13
Identity = 35/104 (33.65%), Postives = 58/104 (55.77%), Query Frame = -1 
Query: 1238 LPKLNKKVDKIENENIFGQLEWKIQNVSQQE------RVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIG------IYFHLLRGEFDDNLVWPFKYVVTIELIN 1513
            L    +++  +E     G+L WKI++ ++++      R   +YS PFY+  FGYKMC  AY     D +G      ++F ++RGE+D  L WPF+  VT+ L++
Sbjct:  251 LDTAERRLQVLETAGYSGKLVWKIRDYARRKQEAASGRTLSLYSQPFYTSPFGYKMCARAYLNG--DGVGRGTHLSLFFVVMRGEYDALLEWPFRRRVTLSLLD 352
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Nematostella
Match: EDO35237 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM27])

HSP 1 Score: 61.6178 bits (148), Expect = 4.331e-10
Identity = 31/89 (34.83%), Postives = 47/89 (52.81%), Query Frame = -1 
Query: 1226 GQLEWKIQNVSQQ------ERVKHIYSNPFYSVKFGYKMCLSAY----FLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNG 1462
            G   WKI   +++           IYS+PFY+ +FGYK+C   +         + + I+  L+RGE+D  L WPF+  +TI LI+  NG
Sbjct:  380 GTFLWKIDKFTERYAEAKSGNATSIYSSPFYTHRFGYKLCARLFPNGDGSARDNYLSIFIALMRGEYDSILPWPFQETITITLIDQDNG 468
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Nematostella
Match: EDO49464 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG36])

HSP 1 Score: 61.2326 bits (147), Expect = 5.937e-10
Identity = 39/114 (34.21%), Postives = 59/114 (51.75%), Query Frame = -1 
Query: 1238 NDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQ--QERVK----HIYSNPFYSVKFGYKMCLSAY----FLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELIN 1549
            N+H + L  I  L + + K+  +E  +  G   WKI   ++  QE V      IYS PFY  ++GYK C   Y     +     + ++F L+RGEFD  L WPF+  VT +L++
Sbjct:  350 NEHQLALHDI-QLAEHDLKLQMLEATSYDGTYIWKIDEYTRRYQEGVSGKTPSIYSPPFYVGRYGYKACARVYPNGDGMGKGSHLSLFFVLMRGEFDALLPWPFRQKVTFKLLD 462
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Nematostella
Match: EDO38873 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SBN4])

HSP 1 Score: 61.2326 bits (147), Expect = 6.664e-10
Identity = 51/194 (26.29%), Postives = 95/194 (48.97%), Query Frame = -1 
Query: 1229 MNMMEDLRMEIKSLKNEII-ELKRNYQNQEEK---KDLLIMK--KAPDEIYK---------QNADSVMR-------LNDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQE------RVKHIYSNPFYSVKFGYKMCLSAYF----LKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKN 1714
            +N ++ +R+  +++ NE I ++ R   N E K    ++L+++   A DE+ +         Q +D ++R       L+D    L+ +  +  L ++++ ++       L WKI NV+ +       RV   YS  F++   GYKMC   Y     +     + ++F ++RGEFD  L WPF+  VT+ L++  N
Sbjct:  229 VNGLQSMRIS-ENIDNEAIGDVLRRVANVEAKGADHEVLVVEAHSAVDELRREVGRLNVKLQESDDIIRRLERQLELHDQGTGLRNLA-IADLEERLNTLQGTTFDSVLLWKITNVANKRSEATSGRVTSFYSPCFFTGPHGYKMCARIYLNGDGMGRNHHVSLFFVIMRGEFDALLRWPFRQKVTLMLLDQDN 420
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Nematostella
Match: EDO48773 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RI91])

HSP 1 Score: 53.1434 bits (126), Expect = 2.323e-7
Identity = 28/100 (28.00%), Postives = 49/100 (49.00%), Query Frame = -1 
Query: 1238 KLNKKVDKIENENIFGQLEWKIQNVSQQER------VKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIG----IYFHLLRGEFDDNLVWPFKYVVTIELIN 1507
            +L  +  ++E     G   WK+ N  Q            I+S PFY+  +GYKMCL      V   +G    ++ H+++G++D  L WPF   +T+ +++
Sbjct:  317 RLETREIELEGRVCNGTFIWKLDNFRQCREGSIAGLTAAIHSPPFYTSMYGYKMCLRMNLNGVDGGLGEHVSLFIHMMQGDWDGILEWPFIGRITLSILD 416
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Nematostella
Match: EDO36181 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SJA2])

HSP 1 Score: 49.2914 bits (116), Expect = 2.471e-7
Identity = 28/76 (36.84%), Postives = 44/76 (57.89%), Query Frame = -1 
Query: 1238 WKIQNVSQQ-ERVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIGIYFHLL----RGEFDDNLVWPFKYVVTIELIN 1450
            W+I+N + Q E+ + I S  FY+ ++GYKM L ++     D  G +  L     +GE+D  L WPFK  +T+ LI+
Sbjct:   19 WRIRNYNDQYEKKQTISSRLFYTSRYGYKMRLKSHLNGNGDGKGTHLSLFVQITKGEYDALLEWPFKRKITLYLID 94
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000027093.1 (general transcription factor II-I repeat domain-containing protein 2B-like [Source:NCBI gene;Acc:111947639])

HSP 1 Score: 290.041 bits (741), Expect = 5.075e-90
Identity = 149/318 (46.86%), Postives = 204/318 (64.15%), Query Frame = 3 
Query:  135 KYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFHC 1088
            KYFFTE  G+  CLIC   VAV K+YN+ RHY  +HE +Y++L+ E R  +   L   L  QQ +  K        V +S++++  +A+  +PF+D EFVK CL+     +CPETK+ F++ISLS RT ARR+E+I  NL  QLK +A  FDC+SLA+DES DI DTAQL+IF+RGI  +F + EELA++ S+KG TTG DLF +V   L+ LEL W+KL  VTTDG  N+ G   G++ R+  ++  I        HCIIHQE LC T+L  MK +++ V  TVN+IR   L HRQF  FL+E  +E+ +    +HC
Sbjct:    8 KYFFTEVKGEAVCLICGAKVAVFKDYNLNRHYTTKHEEKYRNLSDEERAKESEALLQKLQTQQGLLTKLHAPRNAAVRTSFVISHKIARNSKPFSDGEFVKECLLDSVALICPETKSAFENISLSRRTVARRIEDIAGNLELQLKSRAADFDCFSLALDESCDIRDTAQLLIFLRGITAEFQITEELAAMRSMKGTTTGQDLFREVNACLDMLELKWDKLVGVTTDGCPNLTGKNVGLLKRMQDKMTEIV-QKLTFLHCIIHQEVLCKTVL-KMKHVVDVVTKTVNFIRARALNHRQFVAFLEE--NEIEHGDIRYHC 321
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000028655.1 (pep primary_assembly:ASM223467v1:8:18412528:18414615:1 gene:ENSORLG00000023148.1 transcript:ENSORLT00000028655.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 279.641 bits (714), Expect = 3.682e-86
Identity = 143/315 (45.40%), Postives = 201/315 (63.81%), Query Frame = 3 
Query:  126 WNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYE--KEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLN-SLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPM-VFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            W ++Y FTE  GKP CL+C + ++VMKEYN++RH+E  K+H  + K++  E R  K   LK  L +QQ++F      +   V +S+IVAE V K  RPFT+ EF+K C++ V + +CP+ + LF ++SLS  T A R++++ TNL EQL  K K F  YSLA+DES D +D AQL IFIRG+D   ++ EEL +L  L G TTG DL+ +V   +   + L WEKL  +TTDG   MCG ++G+V R+   ++       +  +HCIIHQESLC   L  M+ +M+T+   VN IR  GL HRQFK FL E+D+E
Sbjct:   24 WEAEYMFTEVHGKPVCLLCGERLSVMKEYNLRRHHETSKKHTDKDKNMDTEQRLQKVEELKRGLKSQQALFTIAKSQSGAAVKASFIVAEEVEKSARPFTEGEFIKNCMLKVCDAVCPDKRQLFSNVSLSRNTVAERIDQLSTNLKEQLVGKGKDFIAYSLAVDESTDTSDIAQLSIFIRGVDSSLSITEELLALRPLHGTTTGQDLYEEVSRCVRCEMGLPWEKLVGLTTDGAPAMCGHRSGLVARMRERMREENVTGELTAYHCIIHQESLCGKAL-KMEHVMSTITRAVNLIRARGLNHRQFKAFLGELDTE 337
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000033014.1 (general transcription factor II-I repeat domain-containing protein 2 [Source:NCBI gene;Acc:101164918])

HSP 1 Score: 258.455 bits (659), Expect = 1.264e-77
Identity = 135/328 (41.16%), Postives = 196/328 (59.76%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDN--PMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            +KRK+  EGR F + W   YFFT+      CLIC  +VAV KE+N++RHY+ +H   Y +LTG  R+ K   L+++LT QQSI   +S  ++    +SY VA L+AK  +PFTD EF+K CL+ + E +CPE K  F ++ L   T  +R+E+I   +  QL+ K   F+ +SLA DES D ++TAQL+IF+RG+D D NV EEL  L  L G TTG DLF+ +   ++ + L W K+  + TDG   M   ++G+   +C     +A D    +  HCIIHQE LC   L   + +M  VI+ +N IR     H QF+++L +I +E
Sbjct:    6 KKRKVDYEGRRFQDRWKLAYFFTDIQNNCVCLICQDTVAVFKEFNIRRHYQTKHA-SYDNLTGVQRREKLEQLESALTTQQSICAIKSEPDDNTTQASYEVATLIAKHCKPFTDGEFIKDCLMKIVETICPEKKHEFANVCLDHNTVVQRIEDISIAIKRQLEVKGAKFEFFSLACDESTDASNTAQLLIFLRGVDRDMNVSEELLELQGLTGQTTGTDLFVSLCSAVDDMNLPWNKVSGIITDGTPAMADEQSGLATLVC---NKVAEDGGKAIKLHCIIHQEVLCAKHL-KYEHVMKPVITAINSIRSKARCHHQFQQYLLDIQAE 328
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044825.1 (general transcription factor II-I repeat domain-containing protein 2-like [Source:NCBI gene;Acc:111949247])

HSP 1 Score: 224.557 bits (571), Expect = 2.079e-65
Identity = 124/339 (36.58%), Postives = 183/339 (53.98%), Query Frame = 3 
Query:   81 RKRKIADEGRVFNEEWNSKYFF-TENGGKPFCLICHKSVAVMKEYNVKRHYEKEHE--RQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMV-FHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFH 1085
            R+++   + R F ++W   YFF  E   K  CLIC +SVAV+KEYN++RHYE +H    +YK   GE R+ K   L + L +QQ+                                   + RCL   A  +CP  + +F  ISLS  T  RRVE++  ++ +QL  K++ F  +SLA DES DI+D+AQL++F+RGI+ D  + +ELA L +L+G T G DLF  V   L+   L W+K+  +TTDG   M G K G+   I  ++    C   +  +HCI+HQE LC   +  + D++  V+  +N IR   L HRQF+ FL E+D++  Y   L+H
Sbjct:    3 RQQQWHTDKRHFKQKWEDDYFFFAEISSKAVCLICQQSVAVLKEYNIRRHYETKHAVFSRYK---GEARQKKSSELLSKLRSQQAT----------------------------------LTRCLSTAASIMCPSQERVFSQISLSRNTVTRRVEDLSRDIRDQLTVKSRDFVAFSLACDESTDISDSAQLLVFVRGINADMEITQELAGLETLRGTTKGEDLFAAVSRVLDKYNLSWDKMVGITTDGAPAMIGKKAGLTALISQKVSE--CGGKVAQYHCILHQEQLCAKTI-GLADVVRDVVKIINCIRSKALSHRQFRAFLDEVDAQ--YKDILYH 299
[Close]
BLAST of DUF4371 domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000017252.2 (pep primary_assembly:ASM223467v1:13:14820116:14821987:-1 gene:ENSORLG00000013757.2 transcript:ENSORLT00000017252.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 182.185 bits (461), Expect = 1.648e-49
Identity = 115/346 (33.24%), Postives = 178/346 (51.45%), Query Frame = 3 
Query:   78 SRKRKIADEGRVFNEEWNSKYFF--TENGGKPFCLICHKSVAVMKEYNVKRHYEKEH---ERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAE-----KLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLC-------SLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNP--MVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIR-RHGLKHRQFKEFLKEIDS 1055
            S+ +K+  E R F +EW  KY F       KP CLIC ++VA++K  NVKRHYE +H   E  Y   +  +R +K   LKA       +        +     S  +A ++A+ ++ F+D   VK CL A AE     KL  +     + I LSA T  R+ E +  ++  QL    ++  C SLA+DES D+TD AQL++++R        H+E   +C        L+  T G D++  +KE L   ++  +++  VTTDG   M G++ G V R       +  DNP  + +HCIIHQ  LC  +     ++MNT++  +N++R     +HR  +EFLKE+D+
Sbjct:    4 SKMKKVDAENRTFKDEWTDKYMFILPAASSKPLCLICCENVALIKSGNVKRHYETKHGSFEEMYLQKSA-VRASKIIELKAQYDRSTRVITHAFTGQQRANECSLKIAWILAQHKKAFSDVTVVKECLNAAAETLLDGKLKDDMCEKIKKIPLSATTTTRKTELLAEDVLAQLDAAVQNAACISLAIDESTDVTDNAQLLVYVRF------PHKEKKEMCEDMLGSTPLETHTRGEDIYEGIKEMLTKRKINLKQVVSVTTDGAPAMVGTEKGAVAR-------MKQDNPDLIAYHCIIHQTVLCAILSEEFAEVMNTMMKLINFLRASSSHQHRLLREFLKEMDA 335
[Close]
BLAST of DUF4371 domain-containing protein vs. Planmine SMEST
Match: SMESG000045419.1 (SMESG000045419.1)

HSP 1 Score: 597.816 bits (1540), Expect = 0.000e+0
Identity = 295/330 (89.39%), Postives = 298/330 (90.30%), Query Frame = 3 
Query:   72 MSSRKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSEL 1061
            MSSRKRKIADEGRVFNEEWNSKYFFTENGGKP CLI +KSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIF K                       RPFTD EFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEEL SLCSLK A TGNDLFIKVKETLNSLEL WEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNT+ISTVNYIRRHGLKHRQFK+FLKEIDSE 
Sbjct:    1 MSSRKRKIADEGRVFNEEWNSKYFFTENGGKPLCLIFNKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFMK-----------------------RPFTDLEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELTSLCSLKDAITGNDLFIKVKETLNSLELRWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMNTLISTVNYIRRHGLKHRQFKKFLKEIDSEF 307
[Close]
BLAST of DUF4371 domain-containing protein vs. Planmine SMEST
Match: SMESG000019281.1 (SMESG000019281.1)

HSP 1 Score: 275.404 bits (703), Expect = 1.774e-105
Identity = 136/136 (100.00%), Postives = 136/136 (100.00%), Query Frame = -1 
Query: 1199 MKKAPDEIYKQNADSVMRLNDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQERVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKPLKIKTKK 1606
            MKKAPDEIYKQNADSVMRLNDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQERVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKPLKIKTKK
Sbjct:    1 MKKAPDEIYKQNADSVMRLNDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQERVKHIYSNPFYSVKFGYKMCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKPLKIKTKK 136

HSP 2 Score: 128.257 bits (321), Expect = 1.774e-105
Identity = 60/62 (96.77%), Postives = 61/62 (98.39%), Query Frame = -2 
Query: 1030 KLKQKKYSDCPQHEGWIKPIIETNEGIWFYDIRGKIMSTAIRNNEIIYKCKIIPNRFPSGIL 1215
            K+K KKYSDCPQHEGWIKPIIETNEGIWFYDIRGKIMSTAIRNNEIIYKCKIIPNRFPSGIL
Sbjct:  131 KIKTKKYSDCPQHEGWIKPIIETNEGIWFYDIRGKIMSTAIRNNEIIYKCKIIPNRFPSGIL 192
[Close]
BLAST of DUF4371 domain-containing protein vs. Planmine SMEST
Match: SMESG000037770.1 (SMESG000037770.1)

HSP 1 Score: 254.218 bits (648), Expect = 1.303e-73
Identity = 136/323 (42.11%), Postives = 198/323 (61.30%), Query Frame = 3 
Query:   93 IADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSKTGVVGRICAELQNIACDNPMV-FHCIIHQESLCCTILSSMKDIMNTVISTVNYIRRHGLKHRQFKEFLKEIDSE 1058
            I +E R FN++W SKYFF +      CLIC +SVAV KEYN+KRH++ +H     +L     + K   L  SL  +Q+IF K S   E    +S ++A  + K  +PF++ EFVK C++ +A+ +CPE K  F++ISLS RT  RR+E I  +L +QL  K K+F  +S+A+DES DI DTAQL+IFIRGID  F   EEL S+  LK  TTG DLF  + + L+  EL  +KL  VTTDG  ++ G   G++ +I   ++N+  D+ ++  HCIIHQESLC ++L       NT+++ +           QFK FL++++S+
Sbjct:  529 IEEECRTFNKDWTSKYFFVDIKTNAVCLICRESVAVFKEYNLKRHFQTKHGNFGINLNETELRRKADDLVRSLKQEQTIFLKPSSIQEAATKASLVIAHKIVKHNKPFSEGEFVKDCVLEIADIICPENKKKFENISLSRRTVVRRIESIAEDLSDQLLNKIKTFQWFSIALDESTDIQDTAQLLIFIRGIDDKFIATEELLSMEHLKDTTTGQDLFDNLIKALDKFELPLDKLASVTTDGAPSLTGKNVGLITKIKDHVKNLHPDHTIIPLHCIIHQESLCKSVLD-----FNTLLTLL-----------QFKSFLEDLESD 835
[Close]
BLAST of DUF4371 domain-containing protein vs. Planmine SMEST
Match: SMESG000015269.1 (SMESG000015269.1)

HSP 1 Score: 204.142 bits (518), Expect = 8.108e-58
Identity = 98/218 (44.95%), Postives = 142/218 (65.14%), Query Frame = 3 
Query:  186 KSVAVMKEYNVKRHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHSSYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTCARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDGDFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGRNMCGSK 839
            ++VAVMKEYN++RH+E +H   Y  L  + R  KF  +  SL +QQ++FR  +  NE +   S  +A L+AK  +PF D +  K C++    +LCPE   LF+ ISLS  T ARR+++IG N+  Q+  K + F  YSLAM++S D+ DT+QL+IF+RG+D + NV +ELAS+ S+   TTG D+F +V++TL    L W +L+ VT DGGRNM   K
Sbjct:  125 QTVAVMKEYNIRRHHETKHSSTYSQLKVKDRIEKFEAMHRSLCSQQNLFRNANSENEALTLVSMKIAYLLAKAGKPFMDGQIFKECMMEAVGELCPEKLNLFKMISLSRHTIARRIDDIGNNILHQVTSKTQRFTQYSLAMNKSTDVNDTSQLLIFVRGVDDELNVTQELASVNSMHSTTTGKDIFEEVEKTLLKFNLDWNRLQSVTIDGGRNMSEKK 342
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BLAST of DUF4371 domain-containing protein vs. Planmine SMEST
Match: SMESG000019281.1 (SMESG000019281.1)

HSP 1 Score: 126.716 bits (317), Expect = 1.839e-57
Identity = 60/62 (96.77%), Postives = 61/62 (98.39%), Query Frame = -2 
Query: 1030 KLKQKKYSDCPQHEGWIKPIIETNEGIWFYDIRGKIMSTAIRNNEIIYKCKIIPNRFPSGIL 1215
            K+K KKYSDCPQHEGWIKPIIETNEGIWFYDIRGKIMSTAIRNNEIIYKCKIIPNRFPSGIL
Sbjct:   51 KIKTKKYSDCPQHEGWIKPIIETNEGIWFYDIRGKIMSTAIRNNEIIYKCKIIPNRFPSGIL 112

HSP 2 Score: 116.701 bits (291), Expect = 1.839e-57
Identity = 56/56 (100.00%), Postives = 56/56 (100.00%), Query Frame = -1 
Query: 1199 MCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKPLKIKTKK 1366
            MCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKPLKIKTKK
Sbjct:    1 MCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFKYVVTIELINIKNGKPLKIKTKK 56
The following BLAST results are available for this feature:
BLAST of DUF4371 domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
GTF2IRD2B3.471e-5634.21GTF2I repeat domain containing 2B [Source:HGNC Sym... [more]
GTF2IRD2B8.230e-5634.21GTF2I repeat domain containing 2B [Source:HGNC Sym... [more]
GTF2IRD23.107e-5534.21GTF2I repeat domain containing 2 [Source:HGNC Symb... [more]
GTF2IRD26.068e-5534.21GTF2I repeat domain containing 2 [Source:HGNC Symb... [more]
EPM2AIP13.824e-3125.74EPM2A interacting protein 1 [Source:HGNC Symbol;Ac... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
trf-12.798e-838.30TNF Receptor Associated Factor (TRAF) homolog; TRF... [more]
trf-21.934e-638.10TNF Receptor Associated Factor (TRAF) homolog [So... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF4371 domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AL928808.15.306e-6538.66pep chromosome:GRCz11:20:17257101:17259573:-1 gene... [more]
CR392001.31.125e-4234.30pep chromosome:GRCz11:8:38963323:38965260:-1 gene:... [more]
traf33.032e-1127.11TNF receptor-associated factor 3 [Source:ZFIN;Acc:... [more]
traf59.919e-1026.01Tnf receptor-associated factor 5 [Source:ZFIN;Acc:... [more]
BX901915.14.786e-924.23pep chromosome:GRCz11:CHR_ALT_CTG5_1_18:28764891:2... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
spag11.002e-7442.09sperm associated antigen 1 [Source:Xenbase;Acc:XB-... [more]
ENSXETT00000016563.11.426e-7442.09pep primary_assembly:Xenopus_tropicalis_v9.1:4:373... [more]
ENSXETT00000028445.12.841e-4834.52general transcription factor II-I repeat domain-co... [more]
ENSXETT00000010836.11.539e-1338.14pep primary_assembly:Xenopus_tropicalis_v9.1:7:638... [more]
ssh22.842e-1029.55slingshot protein phosphatase 2 [Source:Xenbase;Ac... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Gtf2ird25.352e-5835.71GTF2I repeat domain containing 2 [Source:MGI Symbo... [more]
Epm2aip12.183e-3226.52EPM2A (laforin) interacting protein 1 [Source:MGI ... [more]
Epm2aip12.183e-3226.52EPM2A (laforin) interacting protein 1 [Source:MGI ... [more]
Zbed57.435e-2427.51zinc finger, BED type containing 5 [Source:MGI Sym... [more]
Med251.955e-1747.56mediator complex subunit 25 [Source:MGI Symbol;Acc... [more]
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BLAST of DUF4371 domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q99NI3|GT2D2_MOUSE3.744e-5735.71General transcription factor II-I repeat domain-co... [more]
sp|A4IFA3|GT2D2_BOVIN1.268e-5534.13General transcription factor II-I repeat domain-co... [more]
sp|Q6EKJ0|GTD2B_HUMAN1.667e-5534.21General transcription factor II-I repeat domain-co... [more]
sp|Q86UP8|GTD2A_HUMAN1.492e-5434.21General transcription factor II-I repeat domain-co... [more]
sp|Q8VEH5|EPMIP_MOUSE1.527e-3126.52EPM2A-interacting protein 1 OS=Mus musculus OX=100... [more]
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BLAST of DUF4371 domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2S2PAF34.149e-12955.35General transcription factor II-I repeat domain-co... [more]
A0A2J7QYZ41.981e-11051.84DUF4371 domain-containing protein OS=Cryptotermes ... [more]
A0A2J7QG634.346e-10851.23DUF4371 domain-containing protein OS=Cryptotermes ... [more]
A0A2J7RR135.632e-10751.38DUF4371 domain-containing protein OS=Cryptotermes ... [more]
I3KZR53.723e-10649.55Uncharacterized protein OS=Oreochromis niloticus O... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSAMXT00000035253.12.636e-9343.29general transcription factor II-I repeat domain-co... [more]
ENSAMXT00000030525.17.400e-8942.34pep primary_assembly:Astyanax_mexicanus-2.0:1:1299... [more]
ENSAMXT00000052542.12.008e-8745.43pep primary_assembly:Astyanax_mexicanus-2.0:APWO02... [more]
ENSAMXT00000037725.11.225e-7342.34pep primary_assembly:Astyanax_mexicanus-2.0:14:291... [more]
ENSAMXT00000036928.12.974e-6743.58pep primary_assembly:Astyanax_mexicanus-2.0:7:1967... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000000074.11.287e-1326.19pep scaffold:Pmarinus_7.0:GL482142:165593:173010:-... [more]
ENSPMAT00000002130.19.590e-1333.65pep scaffold:Pmarinus_7.0:GL484662:8457:12718:-1 g... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of DUF4371 domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO352374.331e-1034.83Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO494645.937e-1034.21Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO388736.664e-1026.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO487732.323e-728.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO361812.471e-736.84Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of DUF4371 domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000027093.15.075e-9046.86general transcription factor II-I repeat domain-co... [more]
ENSORLT00000028655.13.682e-8645.40pep primary_assembly:ASM223467v1:8:18412528:184146... [more]
ENSORLT00000033014.11.264e-7741.16general transcription factor II-I repeat domain-co... [more]
ENSORLT00000044825.12.079e-6536.58general transcription factor II-I repeat domain-co... [more]
ENSORLT00000017252.21.648e-4933.24pep primary_assembly:ASM223467v1:13:14820116:14821... [more]
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BLAST of DUF4371 domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000045419.10.000e+089.39SMESG000045419.1[more]
SMESG000019281.11.774e-105100.00SMESG000019281.1[more]
SMESG000037770.11.303e-7342.11SMESG000037770.1[more]
SMESG000015269.18.108e-5844.95SMESG000015269.1[more]
SMESG000019281.11.839e-5796.77SMESG000019281.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035318 ID=SMED30035318|Name=DUF4371 domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1771bp
TCGCAGCTTTGTAATTATTATTAATATCACTATTATTGTGATTATATATA
TTTTTCAAATAATTTACAAAAATGAGTTCAAGAAAACGTAAAATTGCAGA
TGAAGGAAGAGTTTTTAACGAGGAATGGAACAGCAAGTACTTCTTTACAG
AAAATGGTGGTAAGCCCTTTTGTCTTATTTGTCATAAAAGTGTTGCTGTA
ATGAAAGAATATAATGTCAAACGCCATTACGAGAAAGAACATGAAAGACA
ATACAAGGATTTGACTGGTGAAATTAGAAAAAATAAATTTAGAACATTGA
AAGCTTCTTTGACTGCTCAACAAAGCATATTTAGGAAGCAAAGTATTCAT
AATGAATTGGTTGTTCATTCTAGTTATATTGTAGCGGAACTTGTTGCGAA
AGAAAGAAGGCCTTTTACAGATTCAGAATTTGTTAAGCGATGTTTAGTAG
CTGTAGCGGAAAAATTATGCCCAGAAACCAAGACGTTATTTCAAGATATT
AGCCTATCTGCGCGAACTTGTGCAAGGCGAGTGGAAGAAATAGGAACCAA
TTTATTCGAACAGCTTAAATGTAAAGCAAAATCATTTGATTGTTACTCTC
TAGCAATGGATGAAAGTATTGACATAACTGACACAGCACAGTTAATAATA
TTTATTCGAGGCATTGATGGTGACTTTAATGTTCATGAAGAATTGGCTAG
TTTATGTAGCTTAAAAGGCGCTACAACCGGCAATGATTTGTTCATAAAGG
TAAAGGAAACTCTCAATTCTTTAGAATTGGGATGGGAAAAGTTAAAATGT
GTTACAACCGATGGTGGGAGAAATATGTGTGGCTCTAAAACTGGTGTGGT
AGGCCGAATTTGTGCGGAATTACAGAATATAGCTTGTGATAATCCAATGG
TGTTTCATTGCATCATTCATCAGGAATCACTTTGCTGTACAATTTTATCA
TCAATGAAAGACATTATGAACACGGTGATATCAACTGTGAATTATATTCG
CCGACATGGTCTGAAACACCGTCAATTTAAAGAATTCCTGAAGGAAATCG
ATTCGGAATTATTTTACACTTGTAAATTATTTCATTGTTTCTGATCGCTG
TAGACATTATTTTGCCTCTAATGTCATAAAACCAAATTCCTTCATTTGTT
TCGATTATTGGTTTTATCCATCCTTCGTGTTGAGGACAGTCGGAATATTT
TTTTTGTTTTAATTTTCAAAGGTTTTCCATTCTTTATGTTGATCAACTCA
ATTGTCACAACATATTTGAATGGCCATACTAAATTGTCATCGAATTCTCC
ACGCAATAAATGAAAATAAATACCAATAATATCAACAACTTTAAGAAAAT
ATGCACTCAAGCACATTTTGTATCCAAATTTCACCGAATAAAATGGGTTG
CTATAAATATGTTTTACTCTCTCTTGTTGTGACACATTTTGAATTTTCCA
TTCTAATTGACCGAAAATATTTTCATTTTCTATTTTATCTACTTTCTTGT
TTAATTTTGGTAAATTAATAATTTGTTTTAATTTTACATTATGATCATTT
AATCTCATCACAGAATCTGCATTTTGTTTATAAATTTCATCGGGTGCTTT
TTTCATTATTAACAAATCTTTTTTTTCCTCTTGATTTTGATAATTTCTCT
TTAATTCTATAATTTCATTTTTCAATGATTTTATTTCCATTCGTAAATCT
TCCATCATATTCATTAAATTTTGATGTTTTCCGAAATTTAATCTAAATAT
AAATTTAATTTATAAAACTGA
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protein sequence of SMED30035318-orf-1

>SMED30035318-orf-1 ID=SMED30035318-orf-1|Name=SMED30035318-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=191bp
MNMMEDLRMEIKSLKNEIIELKRNYQNQEEKKDLLIMKKAPDEIYKQNAD
SVMRLNDHNVKLKQIINLPKLNKKVDKIENENIFGQLEWKIQNVSQQERV
KHIYSNPFYSVKFGYKMCLSAYFLKVVDIIGIYFHLLRGEFDDNLVWPFK
YVVTIELINIKNGKPLKIKTKKIFRLSSTRRMDKTNNRNK*
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protein sequence of SMED30035318-orf-2

>SMED30035318-orf-2 ID=SMED30035318-orf-2|Name=SMED30035318-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=341bp
MSSRKRKIADEGRVFNEEWNSKYFFTENGGKPFCLICHKSVAVMKEYNVK
RHYEKEHERQYKDLTGEIRKNKFRTLKASLTAQQSIFRKQSIHNELVVHS
SYIVAELVAKERRPFTDSEFVKRCLVAVAEKLCPETKTLFQDISLSARTC
ARRVEEIGTNLFEQLKCKAKSFDCYSLAMDESIDITDTAQLIIFIRGIDG
DFNVHEELASLCSLKGATTGNDLFIKVKETLNSLELGWEKLKCVTTDGGR
NMCGSKTGVVGRICAELQNIACDNPMVFHCIIHQESLCCTILSSMKDIMN
TVISTVNYIRRHGLKHRQFKEFLKEIDSELFYTCKLFHCF*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0003104enteric muscle cell
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR043211TNF_rcpt-assoc_TRAF
IPR008974TRAF-like
IPR002083MATH/TRAF_dom
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0003676nucleic acid binding
GO:0046983protein dimerization activity
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR008974TRAF-likeGENE3DG3DSA:2.60.210.10coord: 4..154
e-value: 1.4E-25
score: 92.0
IPR008974TRAF-likeSUPERFAMILYSSF49599TRAF domain-likecoord: 50..136
NoneNo IPR availablePANTHERPTHR10131:SF127coord: 18..135
IPR043211TNF receptor-associated factor TRAFPANTHERPTHR10131TNF RECEPTOR ASSOCIATED FACTORcoord: 18..135
IPR002083MATH/TRAF domainPROSITEPS50144MATHcoord: 48..154
score: 9.064