Endothelin-converting enzyme 1

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   + +     GGW    N   P    WD      + K +      TP   + +  D K+S+ N++ +  S L +  R +  N T   N+K+L  + DYM ++G LL  R     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +S    ++V     L  + EL     ++  IL+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   EI++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QY++Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:   63 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKI----GGW----NITGP----WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 736          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   + +     GGW    N   P    WD      + K +      TP   + +  D K+S+ N++ +  S L +  R +  N T   N+K+L  + DYM ++G LL  R     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +S    ++V     L  + EL     ++  IL+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   EI++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QY++Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:   92 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKI----GGW----NITGP----WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 765          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   + +     GGW +           WD      + K +      TP   + +  D K+S+ N++ +  S L +  R +  N T   N+K+L  + DYM ++G LL  R     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +S    ++V     L  + EL     ++  IL+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   EI++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QY++Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:  138 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKI----GGWNIT--------GPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   + +     GGW    N   P    WD      + K +      TP   + +  D K+S+ N++ +  S L +  R +  N T   N+K+L  + DYM ++G LL  R     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +S    ++V     L  + EL     ++  IL+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   EI++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QY++Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:  210 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKI----GGW----NITGP----WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF--EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CL+ +C+     I  S++ +V+PC+DF  + CG W     +P G SR+ TF  +      I K LLEN    + S    KA   Y +C+N  RI  L A PL+  + R     GGW +            D  +V+      +P   + V  D KNS+ N++ +  S L L  R +  N+T  EN+K+L  + +YM  +GKLL    E+    Q  +IL  E  +A     +E +RD E  Y+K+T +E+Q       NW   +      V I  S+   I+V +   L  I  L  +  + + +L+NY++W  V +  +FL + FQ   +KF  V YG   T   RW+ CVS  + ++   LG M++K  F + SK    E+I  +K+ F+ +L +  WMD++TR  A EK D ++ +IGY + I++   L++ F D       YFEN     N +     ++L K P       TP  VNA+YSP KNEI+FPAGILQ PF+    P++L +GGIG  +GHE+ H FDD G +YD  G+LR WW + + + FK +++C V+QYS YS++G  +NG +TLGENIADNGG++  Y+ Y++  KK G E  LP L  T++QLFF+ FA++WC+++T +S    ++++ H+P+ +RVIG+LSN KEF+E F CP GS MNP  KC VW
Sbjct:   81 SVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLEN-STASVSEAERKAQVYYRACMNETRIEELRAKPLMELIER----LGGWNITGPWAKDNFQ--DTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT--ENEKVLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQ-TLAPAINWLPFLNTIFYPVEINESE--PIVVYDKEYLEQISTLINT--TDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEHSLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPI---IRIIVQEDEKNSSRNILNLQLSWLLM---ERQFLQNETKPENKKILDVFKDYMYDVGKLLKI-------RKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASK------KRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQ-TYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIH--GHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGL-NYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C T  C++AA     ++NTSV+PC DF +F CG+W  +  +P     + TF      + +  + LLE  E  T S   + A   Y SC+N  +++ L   PL      T    G W +L  + + T  K++   ++ +   +  +    ++ +  D KN+SRN L +  S L +    R +  N T   +   +  ++ Y+  +  LLK          E      +I+  EIE+AK    E+++R+    YNK  + ++      Q +W    +            D+  +  N T ++     +  + S+        +L NYVLWR V   + +L E F+ IK  F +V  G   +  RW+ C  +    + L  G +Y++ +F +  K + L MI  L+  F + +  N WMD++T++ A+EK ++M   IGY D   ++  L++ +  + I+D  TY+  +         R F+KL K  +    D +P  VNAFYSP KN I FPAGILQ PFF   FP+++ YG IG  +GHEI HGFDD GS+YD  G+L  WW++ +   F T+  C V+QY  Y++      +NG+ T GENIADNGGV+  +Q Y+    + G+E  LPGL  YT++Q+FF+++A  WC  + + + +  +L++ H+P  +RVIG LSN + FA+ + CP+ + +NP  KC+VW
Sbjct:  161 CSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQ-EVVTESESINMARATYRSCMNKTQLDELMTGPLF----ETLTELGEWPLLQENWDKT--KFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSH--MTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYN-LLPQVDWVPFFQS-------IAPSDLTHLFHNETEIIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDHKCIVW 848          

Query:  568 QAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKW-----DLAKVIEDPMVETPIIRIIV----QEDEKNSSRNILNLQLSWLLM---ERQFLQNETKPEN------KKILDVFKDYMYDVGKLLKIRKEKFEQ-FNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMK-LVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYF-----ENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHS--INGENTLGENIADNGGVRLTYQVYKD-LEKKYGKEKLLPGL-NYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +A+  ++KSLN S++PC DF ++ C  W     +P   + YS F      +    +KL E+      S   +   ++Y++C++ ++ N++GA  L+  +      YG W M+ N+      KW     DL K++ +  +++  + +       ED +N SR +L+     L +    R +  +E K E       K  +   + Y  D G  + + + K E   +EI+  E E A+    EED+R+    YN     +++ +Y    +W ++       LV+  +  +  II+++   L  +  L ++  +  RI+ NY+L R        + + ++ ++ +F    YG    + RW+ CVS     +S   G+MY++  F+  +K   L+MI  L++ F+N + +N WMD +T+ +ALEK D M   IGY D ILN   L++ +K +E   +  F     ++I    N    R  E +N+      I +   VNAFYSP +N I FPAGILQ PFF+  FP++L YGGIG  +GHEI HGFDDTG ++D+ G+LR WW + T   F  ++ C ++QY+   + G    ING+ T GENIADNGG++  ++ YK  LEK  G+E  LP   + T++QLFF+ +A++WC  +T ++  + +L++ H+P   RV   L+N  EFAEAF CP GS MNPT +C+VW
Sbjct:   71 EASRLLQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIK----TYGYWPMVHNE------KWRESTFDLTKLLSN-TIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAG--MAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLK-EYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQN--TDPRIVTNYILLRWAGSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVNRF---EFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW 754          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDL-FKIQKKLLENPE-FKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVN------ITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQR-INFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENST-IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIH--GHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            CL+  C++ A  I  S+N+SV+PC DF +F CG+W     +P  +   S F+ +  DL F +++ L EN E +   +    KA   Y+ CLN   I         T  +    ++GGW  L + + P      L   +        + +  VQ D+KNS R++L +    L L  R F       E    L + +D +     L   R        EI+  E  +A     +E + D    Y K+TL E++ +    FNW     R  K ++      IT   + E++V     L  +  L   Y    R++ NY+ W   ++  +  L + F     KF +    +   K RW  CV+ +   M +    +Y+KN+F+ ++K QV EMI+L+ + F + LLS  W+  +T+  A +K++ M   IGY D + +   +   +K  ++    Y++       +      E++ +  +    +     VNAFYSPN NEIIFPAGILQ  F+   FP S+ +GGIG  +GHEI HGFDD G  YD+ G++R WW + T   F+ K+ C  KQYS Y +      ING++T GENIADNGG++  Y+ YK  EK++ +   LPG+N THDQLFF+ +A++WC     +  I  + ++ H+P   RV G LSN  +FA+A+NC  GS MNP +KC VW
Sbjct:   53 CLSPGCIKTASVILSSMNSSVDPCDDFYEFACGQWIKGHPIPDDAPSVSNFENLGQDLEFALKELLDENDEPYDYETSAVGKAKYFYNLCLNESEI----LDNWRTTFDEVVKSFGGWPSLGHQMKPDASIEMLYADMVAKFKADSLFKATVQPDDKNSQRHVLLIDQPQLNLFARDFYVAAENEERMAYLQLIRDVLI---LLDADRTRATLDAKEIIDFETALANITMADEHRHDIAELYTKITLGEMR-RSLPHFNWPLFFNRMFKDLHEKNGKRITFDDNTEVVVYGYEFLRRLDVLIPQY--DNRLIVNYLEWCWFFKTMLRDLPDPFALTIFKFYKTLNIMNVQKVRWHGCVTRINSLMPMATSAIYVKNHFDHEAKQQVEEMISLIMESFVDLLLSEDWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYYQTKFSFYEQYQRDVLERITEAVDRERWVAGAALVNAFYSPNTNEIIFPAGILQPVFYSKDFPSSMNFGGIGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHKAQCIEKQYSSYVLDQINMQINGKSTKGENIADNGGLKQAYRAYKKYEKRHSRPPRLPGVNLTHDQLFFLNYAQIWCGTMNDKEAIRKLRTSEHSPGPIRVKGPLSNSYDFAKAYNCEPGSQMNPREKCRVW 736          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPI---IRIIVQEDEKNSSRNILNLQLSWLLM---ERQFLQNETKPENKKILDVFKDYMYDVGKLLKI-------RKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASK------KRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQ-TYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIH--GHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGL-NYTHDQLFFITFARLWC 2424
            C T  C++AA     ++NTSV+PC DF +F CG+W  +  +P     + TF      + +  + LLE  E  T S   + A   Y SC+N  +++ L   PL      T    G W +L  + + T  K++   ++ +   +  +    ++ +  D KN+SRN L +  S L +    R +  N T   +   +  ++ Y+  +  LLK          E      +I+  EIE+AK    E+++R+    YNK  + ++      Q +W    +            D+  +  N T ++     +  + S+        +L NYVLWR V   + +L E F+ IK  F +V  G   +  RW+ C  +    + L  G +Y++ +F +  K + L MI  L+  F + +  N WMD++T++ A+EK ++M   IGY D   ++  L++ +  + I+D  TY+  +         R F+KL K  +    D +P  VNAFYSP KN I FPAGILQ PFF   FP+++ YG IG  +GHEI HGFDD GS+YD  G+L  WW++ +   F T+  C V+QY  Y++      +NG+ T GENIADNGGV+  +Q Y+    + G+E  LPGL  YT++Q+FF+++A + C
Sbjct:  161 CSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLEQ-EVVTESESINMARATYRSCMNKTQLDELMTGPLF----ETLTELGEWPLLQENWDKT--KFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSH--MTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYN-LLPQVDWVPFFQS-------IAPSDLTHLFHNETEIIICEIEYLQHVSELIEKTDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFDKHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAHVSC 793          

Query:  487 SSTMGTRRVISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVK-LYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTL--DKWD---------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMER-QFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTK--ERWEHCVSIVQVHMSLILGNMYIKNNFNKQ-SKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMY-RNFEKLNKRPENST-IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSI--NGENTLGENIADNGGVRLTYQVYKDLEKKYG--KEKLLPGL-NYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +S++   R   N N   D  C +  C++ A  + ++LN+ +NPC DF +F CG +   + LP       T   V + L K  K +L++P    N   + K  K  Y  CL+ + + S G   +     R     GGW        PTL  DKW          +A V+    V   I+ + V  D  NSSR+++ L Q  W    R  +L     P  +    + K     +G    I ++   + NE ++ E+++      +  +RDPE   N+  L +++  +    N+ + ++   K + + +S +  +IV      + I  + +S  + KR+L NY+ WR V     FL    +    +F+    G+  +   +RWE CV++  + M + +G ++++N F K+ +  ++ E+ + LK +F   L    WMD+ TR  A+ K + +    G+   + N T++E+ +  I I  + Y  ++ +      +     +L++  + S    +P +V+A+Y+PN NE+IFPAGI+Q PF   G P  + YG +G  +GHE+ H FDD G +YD  G+L  WW   T + F  K+ CFV+QY    +    I  NG+ +LGENIADNGGV+  +  YK  +       E  LPG  N+T  Q+FF+ +A  WC+L   +  I  IL++ H P+ YR +  L N  EFA+AF CP GS MNP  KC VW
Sbjct:   69 NSSVAVDRSAKNHN---DVVCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSP-ISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRI----GGW--------PTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKWGAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEK---EMNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVF-PFINFEKYLKTVFKEL-VALSPNHTVIVREIDYFVGIQHVLQS--TPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMI-IKPREYLLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 769          

Query:  487 SSTMGTRRVISNQNRELDSP------CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLD-RINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLA---KVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRK-EKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNP---TNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENST--IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
             S+  T+ V+  Q  + D P      CL   C+ A+ EI KS++ +V+PC DF  + C +W     +P+G S + TF  +      I + +LE P     S    KA   Y+SCL+ D  +  LGA P+    N      GGW +  +  N  +  W +    K++ +      +    + ED+KNSSR+++ +    L +      N     ++K+L+ + +YM  V  LL   + +   Q   ++  E ++A      ED+R+ E+ Y+ M L ++  K     NWT+     M++V   ++ D  ++V  P    NL DI    +     K  L+NY++W+ V    + LS+ F+      R+   G  G +E W +CVS     +   +G ++++  F+ +SKP   +MI  +++ F+ NL +  W+D QTR  A+EK + +  +IG+ D IL+   L++ + ++ I    YFEN   +    +  N ++L++ P N T    TPQ VNA+Y+P KN+I+FPAGILQ PFF+   P+SL +G +G  MGHE+ H FDD G +YD  G++  WW  ++ + F  KS+C  +QYS Y ++G ++NG+ TLGENIADNGG++  Y  Y+  +     + L LPGLN TH QLFF++FA++WC+  T ++ ++ +  + H+P+ +RVIGTLSN KEFAE F C  G  MNPT+KC VW
Sbjct:   77 GSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPM----NDLLLQIGGWNVTKSGYN--VANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLS-KLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQ-PVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  487 SSTMGTRRVISNQNRELDSP------CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLD-RINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLA---KVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRK-EKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNP---TNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENST--IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
             S+  T+ V+  Q  + D P      CL   C+ A+ EI KS++ +V+PC DF  + C +W     +P+G S + TF  +      I + +LE P     S    KA   Y+SCL+ D  +  LGA P+    N      GGW +  +  N  +  W +    K++ +      +    + ED+KNSSR+++ +    L +      N     ++K+L+ + +YM  V  LL   + +   Q   ++  E ++A      ED+R+ E+ Y+ M L ++  K     NWT+     M++V   ++ D  ++V  P    NL DI    +     K  L+NY++W+ V    + LS+ F+      R+   G  G +E W +CVS     +   +G ++++  F+ +SKP   +MI  +++ F+ NL +  W+D QTR  A+EK + +  +IG+ D IL+   L++ + ++ I    YFEN   +    +  N ++L++ P N T    TPQ VNA+Y+P KN+I+FPAGILQ PFF+   P+SL +G +G  MGHE+ H FDD G +YD  G++  WW  ++ + F  KS+C  +QYS Y ++G ++NG+ TLGENIADNGG++  Y  Y+  +     + L LPGLN TH QLFF++FA++WC+  T ++ ++ +  + H+P+ +RVIGTLSN KEFAE F C  G  MNPT+KC VW
Sbjct:   77 GSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPM----NDLLLQIGGWNVTKSGYN--VANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLS-KLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQ-PVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  487 SSTMGTRRVISNQNRELDSP------CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLD-RINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLA---KVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRK-EKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNP---TNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENST--IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
             S+  T+ V+  Q  + D P      CL   C+ A+ EI KS++ +V+PC DF  + C +W     +P+G S + TF  +      I + +LE P     S    KA   Y+SCL+ D  +  LGA P+    N      GGW +  +  N  +  W +    K++ +      +    + ED+KNSSR+++ +    L +      N     ++K+L+ + +YM  V  LL   + +   Q   ++  E ++A      ED+R+ E+ Y+ M L ++  K     NWT+     M++V   ++ D  ++V  P    NL DI    +     K  L+NY++W+ V    + LS+ F+      R+   G  G +E W +CVS     +   +G ++++  F+ +SKP   +MI  +++ F+ NL +  W+D QTR  A+EK + +  +IG+ D IL+   L++ + ++ I    YFEN   +    +  N ++L++ P N T    TPQ VNA+Y+P KN+I+FPAGILQ PFF+   P+SL +G +G  MGHE+ H FDD G +YD  G++  WW  ++ + F  KS+C  +QYS Y ++G ++NG+ TLGENIADNGG++  Y  Y+  +     + L LPGLN TH QLFF++FA++WC+  T ++ ++ +  + H+P+ +RVIGTLSN KEFAE F C  G  MNPT+KC VW
Sbjct:   77 GSSDATKHVLHVQPHQKDCPSGNELPCLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPM----NDLLLQIGGWNVTKSGYN--VANWTMGHTLKILHNKYNFNCLFGWAIGEDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIGVINFEKKLANITIPLEDRRNEEAMYHPMQLRQLS-KLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQ-PVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  538 DSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKW--DLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKE-KFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDT-PQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIH--GHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            D+ C+T  C++ A  +  +++ + +PC DF Q+ CG W     +P+  S  STF+V++     I + +LE P  + ++    KA   + SC+++ +I  +G       L +   + GGW ++  + +P  D     L   +     E  +I + V  D+KNSS NIL + QL + L  R +   E+   +++    +  YM  V  LL         +  +++  E ++      E D+ D    Y KM L E+Q +   +  W E ++  +    I + +D  ++      L ++ ++     + +R++HNY+LWR V   ++ + +++QR + +FR++  G+   + RW  CV      + + +G ++I++NFN++SK   LEMI+ ++  F   L  N WMDD+TR+ A EK D+M   IGY + + N T LE+ + ++ I    +  N+  +      +    L +  +     T P  VNAFY+PNKN+I+FPAGILQ  F+   FP+SL YGGIG  +GHEI HGFDD G ++D +G++  WW + T + F+ ++ C + QYS+Y I+     ++G  T GENIADNGG++  ++ YK  E  +G+E+ LPGLN THDQLFF+ +A++WC     +  +  I S  H+P   RV+G LSN ++FA A+ CP GS MNP +KC VW
Sbjct:  170 DNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIG----TGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRR---AYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQ-ELVPEVQWQEYLQAALG-PGIPLQEDEPLVTYGLHYLTEMGKILAH--TDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849          

Query:  538 DSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKW--DLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKE-KFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDT-PQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIH--GHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            D+ C+T  C++ A  +  +++ + +PC DF Q+ CG W     +P+  S  STF+V++     I + +LE P  + ++    KA   + SC+++ +I  +G       L +   + GGW ++  + +P  D     L   +     E  +I + V  D+KNSS NIL + QL + L  R +   E+   +++    +  YM  V  LL         +  +++  E ++      E D+ D    Y KM L E+Q +   +  W E ++  +    I + +D  ++      L ++ ++     + +R++HNY+LWR V   ++ + +++QR + +FR++  G+   + RW  CV      + + +G ++I++NFN++SK   LEMI+ ++  F   L  N WMDD+TR+ A EK D+M   IGY + + N T LE+ + ++ I    +  N+  +      +    L +  +     T P  VNAFY+PNKN+I+FPAGILQ  F+   FP+SL YGGIG  +GHEI HGFDD G ++D +G++  WW + T + F+ ++ C + QYS+Y I+     ++G  T GENIADNGG++  ++ YK  E  +G+E+ LPGLN THDQLFF+ +A++WC     +  +  I S  H+P   RV+G LSN ++FA A+ CP GS MNP +KC VW
Sbjct:  170 DNICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDERDNKATIKAKTFFKSCMDIPQIRKIG----TGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRR---AYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQ-ELVPEVQWQEYLQAALG-PGIPLQEDEPLVTYGLHYLTEMGKILAH--TDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK---WDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C+  A +I ++L+ S +PC DF Q+ CG W  +  LP G SR+STF+ +      + K LLEN  F ++S    K    Y SCLN  RI  LGA PL+  + +     GGW     ++  + DK    D+ K+I  P    P   + V  D KNS+ N++ +  S L +  R +  N+T   N+K+L  + DYM ++G LL   K     Q  +IL  E  +A     ++++RD E  Y+K+T++++Q        W + +   +  + +  ++   ++V     +  + EL     +   +L+NY++W  V +  + L + F+  +DK     YG   +   RW+ C+      +   LG +++K  F+KQSK     MIN ++  F+  L    WMD+QTR  A +K D ++ +IG+ D IL+   L++ +   E+ +  +F+N+    N +     ++L K P       TP  VNA+Y P KN I+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY++Y+I+G  ING+ TLGENIADNGG++  Y  Y+   +K G+EK LP +N T+DQLFF+ FA++WC+++T +S    ++++ H+P  YRVIGTLSN  EFAE F CP GS MN   +C VW
Sbjct:   93 SICLTEACVTVASKIVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKI----GGW-----NITESWDKENFLDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKT---NEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALANITVPQDERRDEEKIYHKITIADLQ-VLAPAIEWLDYLNSVLSPLELNDTE--PVVVYAKEYMQQVSELINK--TDHSLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKQSKEIAEGMINEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVQKNGEEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGHRCEVW 765          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRT--FGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQF-NEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            CL+  C+  A  +  SL+ SV+PC DF  F CG W  +  LP+G SR+  F  +      + K LLEN   K+ S    KA   Y +C+N  +I  LGA PL   +N+T  +G  G WE   ++    L      +++      +P   + V  D K+S+ NI+ +  S L L  R++  N+T   N+K L+ + +++ ++G LL   ++  ++   EI++ E  +A     + ++RD E  Y K+   E+        +W   +      V +  S+   ++V     L  + EL  +  + K +L+NY++ + V + ++ L + FQ  + +F  V YG   +   RW+ CVS     +   LG +++K  F++ SK  V +M++ +K  F+++L +  WMD +T+  A EK D ++ ++GY   I+N   L++ F D ++    YF+N+    N +     ++L K P       TP  VNA+Y+P KNE++ PAGI Q PF+   +P+++ +GGIG  MGHE+ H FDD G KYD  G+L  WW + + + F+ ++ C V+QYS YSI+   +NG++TLGENIADNGG+   Y+ Y +  KK G+E  LP L   + QLFF+ FA++WC+++T +S    ++++ H+P+ +RVIGT+SN  EF+E F C   S MNP  KC +W
Sbjct:   81 CLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLINQTGGWGLKGPWE--KDNFQEVL------RIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTA--NEKYLNAYLNFLVELGVLLGGSQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKEL-ATLAPAIDWMPFLSSVFAPVELNDSE--PVVVYAKEYLQKVSELISN--TNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFLEVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNPKRKCELW 752          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRT--FGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQF-NEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            CL+  C+  A  +  SL+ SV+PC DF  F CG W  +  LP+G SR+  F  +      + K LLEN   K+ S    KA   Y +C+N  +I  LGA PL   +N+T  +G  G WE   ++    L      +++      +P   + V  D K+S+ NI+ +  S L L  R++  N+T   N+K L+ + +++ ++G LL   ++  ++   EI++ E  +A     + ++RD E  Y K+   E+        +W   +      V +  S+   ++V     L  + EL  +  + K +L+NY++ + V + ++ L + FQ  + +F  V YG   +   RW+ CVS     +   LG +++K  F++ SK  V +M++ +K  F+++L +  WMD +T+  A EK D ++ ++GY   I+N   L++ F D ++    YF+N+    N +     ++L K P       TP  VNA+Y+P KNE++ PAGI Q PF+   +P+++ +GGIG  MGHE+ H FDD G KYD  G+L  WW + + + F+ ++ C V+QYS YSI+   +NG++TLGENIADNGG+   Y+ Y +  KK G+E  LP L   + QLFF+ FA++WC+++T +S    ++++ H+P+ +RVIGT+SN  EF+E F C   S MNP  KC +W
Sbjct:   81 CLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLINQTGGWGLKGPWE--KDNFQEVL------RIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTA--NEKYLNAYLNFLVELGVLLGGSQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKEL-ATLAPAIDWMPFLSSVFAPVELNDSE--PVVVYAKEYLQKVSELISN--TNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFLEVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNPKRKCELW 752          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK-W---DLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGK-------LLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKY-CQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNV--TYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPE-NSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS---IHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C T  C+ AA  + ++++ SV+PC +F Q+ CG W    ++P+ SS +S F+++  +L  + K +LE  E K +   + KA  LY SC+N   I    + PL+    R   + G W + +   N T ++ W   D   V+     +  ++ + V  D+++SSR I+++    L M  R +  ++     KK+ + + ++M  + +       L +  +   E  +++L+LE +IA      E++ D    YNKMTL E Q  +    FNWT  ++  M  V+I++  D  I++     L  + E+   ++   R L NY++W  +  R++ +S  F+ ++  +R+  +G    + RW  CV  VQ +M   +G +Y++  F+  SK  V E+I  +++ +   L    WMD+Q++  A EK   +   IGY D IL      L++ +  +  +++ YFENI      +  +  +KL +  + +  I     VNAFYS N+N+I+FPAGILQ PFF     ++L +GGIG  +GHEI HGFDD G  +D  G++  WW++ + + F+ +S C V+QY ++S     G +++G  TLGENIADNGGVR  Y+ Y    ++ G+E  LPGL+  H QLFF+ FA++WC     +  I  I ++ H+P  YRV+G+L NF+ F+EAF+C +G+ MNP +KC VW
Sbjct:   65 CTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERHVIPETSSLHSVFNILRDELEIVLKGVLEM-ENKDDREAFKKAKTLYSSCMNEILIEQRDSQPLL----RLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLNGRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGN--YKKVREAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLSKHS--HRTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVSGITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW 755          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK-W---DLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGK-------LLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKY-CQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNV--TYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPE-NSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS---IHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C T  C+ AA  + ++++ SV+PC +F Q+ CG W    ++P+ SS +S F+++  +L  + K +LE  E K +   + KA  LY SC+N   I    + PL+    R   + G W + +   N T ++ W   D   V+     +  ++ + V  D+++SSR I+++    L M  R +  ++     KK+ + + ++M  + +       L +  +   E  +++L+LE +IA      E++ D    YNKMTL E Q  +    FNWT  ++  M  V+I++  D  I++     L  + E+   ++   R L NY++W  +  R++ +S  F+ ++  +R+  +G    + RW  CV  VQ +M   +G +Y++  F+  SK  V E+I  +++ +   L    WMD+Q++  A EK   +   IGY D IL      L++ +  +  +++ YFENI      +  +  +KL +  + +  I     VNAFYS N+N+I+FPAGILQ PFF     ++L +GGIG  +GHEI HGFDD G  +D  G++  WW++ + + F+ +S C V+QY ++S     G +++G  TLGENIADNGGVR  Y+ Y    ++ G+E  LPGL+  H QLFF+ FA++WC     +  I  I ++ H+P  YRV+G+L NF+ F+EAF+C +G+ MNP +KC VW
Sbjct:   75 CTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERHVIPETSSLHSVFNILRDELEIVLKGVLEM-ENKDDREAFKKAKTLYSSCMNEILIEQRDSQPLL----RLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLNGRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGN--YKKVREAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLSKHS--HRTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVSGITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW 765          

Query:  514 ISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +++++R L   CL+ +C+  A  I  SL+  ++PC DF Q+ CG W     LP G SR++TF+ +      I K +LEN  F ++S    K  + Y SCL   RI  L   PL   + +     GGW +  N          + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N+T   N K+LD +  YM  VG+LL       + Q  +IL+ E  +A     ++++RD E  YN+MT+SE+Q      F+W + +     L  + ++    ++V     L  + EL  +  +   +L+NY++W  V +  + L   F++ +DK     YG   +   RW+ C+S     +   LG++++K+ F+K SK    +MI+ ++  F+  L    WMD++TR  A EK D ++ +IG+ D IL+   L+E +   E+++  +F+N+    N +     E+L K P       TPQ VNA+Y PNKNEI+FPAGILQ PF+ P  P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY+ Y+++G  +NG  TLGENIADNGG++  Y  YK    K+G+EK LPG+  T++QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCPKG+ MNP   C VW
Sbjct:   87 MTDRSRSL---CLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKI----GGWNISGNWRGENF--MSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTA--NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQ-SLAPAFDWMDYLT--FALSPLDLNDTEPVVVYGKEYLQQVSELVNN--TDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 766          

Query:  514 ISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +++++R L   CL+ +C+  A  I  SL+  ++PC DF Q+ CG W     LP G SR++TF+ +      I K +LEN  F ++S    K  + Y SCL   RI  L   PL   + +     GGW +  N          + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N+T   N K+LD +  YM  VG+LL       + Q  +IL+ E  +A     ++++RD E  YN+MT+SE+Q      F+W + +     L  + ++    ++V     L  + EL  +  +   +L+NY++W  V +  + L   F++ +DK     YG   +   RW+ C+S     +   LG++++K+ F+K SK    +MI+ ++  F+  L    WMD++TR  A EK D ++ +IG+ D IL+   L+E +   E+++  +F+N+    N +     E+L K P       TPQ VNA+Y PNKNEI+FPAGILQ PF+ P  P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY+ Y+++G  +NG  TLGENIADNGG++  Y  YK    K+G+EK LPG+  T++QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCPKG+ MNP   C VW
Sbjct:   76 MTDRSRSL---CLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKI----GGWNISGNWRGENF--MSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTA--NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQ-SLAPAFDWMDYLT--FALSPLDLNDTEPVVVYGKEYLQQVSELVNN--TDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 755          

Query:  514 ISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +++++R L   CL+ +C+  A  I  SL+  ++PC DF Q+ CG W     LP G SR++TF+ +      I K +LEN  F ++S    K  + Y SCL   RI  L   PL   + +     GGW +  N          + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N+T   N K+LD +  YM  VG+LL       + Q  +IL+ E  +A     ++++RD E  YN+MT+SE+Q      F+W + +     L  + ++    ++V     L  + EL  +  +   +L+NY++W  V +  + L   F++ +DK     YG   +   RW+ C+S     +   LG++++K+ F+K SK    +MI+ ++  F+  L    WMD++TR  A EK D ++ +IG+ D IL+   L+E +   E+++  +F+N+    N +     E+L K P       TPQ VNA+Y PNKNEI+FPAGILQ PF+ P  P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY+ Y+++G  +NG  TLGENIADNGG++  Y  YK    K+G+EK LPG+  T++QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCPKG+ MNP   C VW
Sbjct:   85 MTDRSRSL---CLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKI----GGWNISGNWRGENF--MSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTA--NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQ-SLAPAFDWMDYLT--FALSPLDLNDTEPVVVYGKEYLQQVSELVNN--TDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 764          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEET--FKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CL+ +C+  A  I  SL+  ++PC DF Q+ CG W     LP G SR++TF+ +      I K +LEN  F ++S    K  + Y SCL   RI  L   PL   + +     GGW +  N          + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N+T   N K+LD +  YM  VG+LL       + Q  +IL+ E  +A     ++++RD E  YN+MT+SE+Q      F+W + +     L  + ++    ++V     L  + EL  +  +   +L+NY++W  V +  + L   F++ +DK     YG   +   RW+ C+S     +   LG++++K+ F+K SK    +MI+ ++  F+  L    WMD++TR  A EK D ++ +IG+ D IL+   L+ET      ++++  +F+N+    N +     E+L K P       TPQ VNA+Y PNKNEI+FPAGILQ PF+ P  P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY+ Y+++G  +NG  TLGENIADNGG++  Y  YK    K+G+EK LPG+  T++QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCPKG+ MNP   C VW
Sbjct:    8 SLCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKI----GGWNISGNWRGENF--MSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTA--NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQ-SLAPAFDWMDYLT--FALSPLDLNDTEPVVVYGKEYLQQVSELVNN--TDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDETGLLYTAKVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 683          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CL+ +C+  A  I  SL+  ++PC DF Q+ CG W     LP G SR++TF+ +      I K +LEN  F ++S    K  + Y SCL   RI  L   PL   + +     GGW +  N          + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N+T   N K+LD +  YM  VG+LL       + Q  +IL+ E  +A     ++++RD E  YN+MT+SE+Q      F+W + +     L  + ++    ++V     L  + EL  +  +   +L+NY++W  V +  + L   F++ +DK     YG   +   RW+ C+S     +   LG++++K+ F+K SK    +MI+ ++  F+  L    WMD++TR  A EK D ++ +IG+ D IL+   L+E +  +  ++  +F+N+    N +     E+L K P       TPQ VNA+Y PNKNEI+FPAGILQ PF+ P  P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY+ Y+++G  +NG  TLGENIADNGG++  Y  YK    K+G+EK LPG+  T++QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCPKG+ MNP   C VW
Sbjct:   59 SLCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKI----GGWNISGNWRGENF--MSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTA--NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQ-SLAPAFDWMDYLT--FALSPLDLNDTEPVVVYGKEYLQQVSELVNN--TDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGV--SEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 730          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN-DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S C+T +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K    Y SCL  +RI  LGA PL   +++     GGW +    D +  +D   + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +     ++V     L  + EL     ++  IL+NY++W  V +  + L + F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MIN ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:   61 STCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKI----GGWNITGPWDEDSFMD---VLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 734          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN-DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S C+T +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K    Y SCL  +RI  LGA PL   +++     GGW +    D +  +D   + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +     ++V     L  + EL     ++  IL+NY++W  V +  + L + F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MIN ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:   90 STCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKI----GGWNITGPWDEDSFMD---VLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 763          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN-DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S C+T +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K    Y SCL  +RI  LGA PL   +++     GGW +    D +  +D   + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +     ++V     L  + EL     ++  IL+NY++W  V +  + L + F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MIN ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:  237 STCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKI----GGWNITGPWDEDSFMD---VLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 910          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN-DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S C+T +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K    Y SCL  +RI  LGA PL   +++     GGW +    D +  +D   + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +     ++V     L  + EL     ++  IL+NY++W  V +  + L + F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MIN ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:  208 STCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKI----GGWNITGPWDEDSFMD---VLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 881          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF--EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTK-ERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            CLT +C+     I  S++ +V+PC DF  + CG W     +P G SR+ TF  +      + K LLEN      S    KA   Y +C+N  RI  L A PL+  + +     GGW +            D  +V+      +P   + V  D KNS+ N++ +  S L L  R +  N+T  EN+K+L  + +YM  +GKLL    E     Q  +IL  E  +A     +E +RD E  Y+K+T +E+Q       NW   +      V I  S+   I+V +   L  +  L  +  + K +L+NY++W  V +  +FL + FQ   +KF  V YG   T   RW+ CVS  + ++   LG M++K  F + SK    E+I  +K+ F+ +L +  WMD++TR  A EK D ++ +IGY + I++   L++ F D       YFEN     N +     ++L K P       TP  VNA+YSP KNEI+FPAGILQ PF+    P +L +GGIG  +GHE+ H FDD G +YD  G+LR WW + + + FK +++C V+QYS YS++G  +NG +TLGENIADNGG++  Y+ Y++  KK G E+ LP L  T +QLFF+ FA++WC+++T +S    ++++ H+P+ +RVIG+LSN KEF+E F CP GS MNP  KC VW
Sbjct:   82 CLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLENATASV-SEAERKAQVYYRACMNETRIEELRAKPLMELIEK----LGGWNITGPWAKDNFQ--DTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKT--ENEKVLTGYLNYMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQ-TLAPAINWLPFLNTIFYPVEINESE--PIVVYDKEYLRQVSTLINN--TDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFMEVMYGTKKTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQTLPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPHHKCEVW 753          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   + +     GGW +           WD      + K +      TP   + +  D K+S+ N++ +  S L +  R +  N T   N+K+L  + DYM ++G LL  R     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +S    ++V     L  + EL     ++  IL+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   EI++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QY++Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:  138 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKI----GGWNIT--------GPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 811          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   + +     GGW    N   P    WD      + K +      TP   + +  D K+S+ N++ +  S L +  R +  N T   N+K+L  + DYM ++G LL  R     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +S    ++V     L  + EL     ++  IL+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   EI++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QY++Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:  210 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKI----GGW----NITGP----WDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPSMDWLEFLS--FLLSPLELSDSEPVVVYGMDYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYGTKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 883          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   +++     GGW    N   P    WD      + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM+++E+Q       +W E +     L  + +     ++V     L  + EL     ++  +L+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MN    C VW
Sbjct:   92 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKI----GGW----NVTGP----WDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQA-LAPSMDWLEFLS--FLLSPLELGDSEPVVVYGTDYLQQVSELINR--TEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW 765          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN-DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S C+T +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K    Y SCL  +RI  LGA PL   +++     GGW +    D +  +D   + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM++SE+Q       +W E +     L  + +     ++V     L  + EL     ++  IL+NY++W  V +  + L + F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MIN ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MNP   C VW
Sbjct:   90 STCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLRDLIDKI----GGWNITGPWDEDSFMD---VLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQA-LAPAVDWLEFLS--FLLSPLELGDSEPVVVYGTEYLQQVSELINR--TEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 763          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C++ A +I +SL+  V+PC DF QF CG W     LP G SR++TF+ +      I K LLEN  F ++S    K  + Y SCL ++RI  LGA PL   +++     GGW    N   P    WD      + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N T   N+K+L  + DYM ++G LL  +     EQ  ++L+LEI++A     ++ +RD E  Y+KM+++E+Q       +W E +     L  + +     ++V     L  + EL     ++  +L+NY++W  V +  + L   F+  ++K     YG   +   RW+ C+S     +   LG++++K  F++QSK     MI+ ++  F+  L   VWMD++TR  A EK D ++ +IG+ D IL    L++ +   E+++ ++F+N+  L N +     ++L K P       TPQ VNA+Y P KNEI+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + +   F+  + C  +QYS+Y ++G  +NG  TLGENIADNGG++  Y  YK   +K+G+E+ LP +  T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RV+GTLSN ++F   F CP GS MN    C VW
Sbjct:  210 STCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTQRFYLSCLQVERIEELGAQPLRDLIDKI----GGW----NVTGP----WDQDNFMEVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTA--NEKVLTAYLDYMEELGMLLGGQPTSTREQMRQVLELEIQLANITVPQDQRRDEEKIYHKMSIAELQA-LAPSMDWLEFLS--FLLSPLELGDSEPVVVYGTDYLQQVSELINR--TEPSVLNNYLIWNLVQKTTSSLDHRFESAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRAAFEEALGHLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYTCNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACIEEQYSQYQVNGEKLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNSGQLCEVW 883          

Query:  544 PCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN------DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQF--NEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRR-MKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGV-VGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEIN-DQTYFEN----IDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGK-EKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            PC T +C+  A ++  SL+ SV+PC DF +F CG W+   +LP G SR+S F+ +      I K +LE    + NS    KA   Y+SC++L+ IN  GA PL+T L +     GGW +L N      D N T+ ++        P    P   I V  D K+S+ NI+ +  S L L  R F  N+T  E+ KIL  + DYM +V  LL  +     +F   E+L+LE ++A      E+ R+ E  Y++M L+++Q       +W+ +V    +KL N T+  +  +I  +   L +  ++   Y + KR+L NY  WR V+  ++ L + F    +KF +V YG  +   ERW  C++ V   + L +G ++++  F+K SK    EM+  +K  FQ NL    WMD  TR  A EK   +  +IG+ D ILN+TY+ E +K++ ++ ++ +FE+    +  +T + + ++  K  KR E S   TP  VNA+YSP KN I+FPAGILQ PF+   FP+S+ YGGIG  +GHE+ HGFDD G +YD  G+L  WW   T   FK K++C V+QY  ++  G  +NG  TLGENIADNGGVRL Y  Y++ +K  G  E  LP LNYTHDQLFFI+FA+LWC++ T Q     +L + H+P   RVIGTLSNF+EF++AF+CPKGS MNP  KC VW
Sbjct:   21 PCTTRACINVASKVALSLDESVDPCQDFYEFACGGWEESNLLPSGESRWSGFNALQQSNHAIMKNVLELNTTQNNSVAEKKAKIFYESCIDLEAINKRGAQPLLTMLEKV----GGWPVLNNWDESSFDFNATIQQYF-------PYSIYPFFSIGVNTDSKHSNSNIVIVGESGLSLGTRDFYVNKTI-EDDKILHAYLDYMTEVATLLGAKDRNITRFRMKEVLELEKKLAIISLPLEEMRNEEKNYHRMVLADLQ-DLAPAVDWSNLVPELFLKLANETVGTNEPVITFSRQYLRNFSDIV--YQTPKRVLGNYFGWRFVHSFVSALGQPFLEALNKFHKVQYGSNMNCVERWRRCLNTVDSVLGLAVGRLFVQKKFDKTSKSSAEEMVREIKASFQKNLPKTSWMDPVTRKKASEKCSAVEDMIGFDDKILNITYVNEKYKNLIVDPNKGHFEHHVSVVRYITVKEL-KHLRKPVKRKEWSI--TPPTVNAYYSPTKNIIVFPAGILQPPFYSSNFPKSINYGGIGIVVGHELTHGFDDQGRQYDLNGNLNNWWQKDTLAKFKKKAECMVEQYGSFNFGGAQVNGVLTLGENIADNGGVRLAYNAYQEWKKANGSLETQLPSLNYTHDQLFFISFAQLWCSVSTPQFRKHQVLVDMHSPPKARVIGTLSNFEEFSKAFSCPKGSPMNPAKKCKVW 701          

Query:  544 PCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN------DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQF--NEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRR-MKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGV-VGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEIN-DQTYFEN----IDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGK-EKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            PC T +C+  A ++  SL+ SV+PC DF +F CG W+   +LP G SR+S F+ +      I K +LE    + NS    KA   Y+SC++L+ IN  GA PL+T L +     GGW +L N      D N T+ ++        P    P   I V  D K+S+ NI+ +  S L L  R F  N+T  E+ KIL  + DYM +V  LL  +     +F   E+L+LE ++A      E+ R+ E  Y++M L+++Q       +W+ +V    +KL N T+  +  +I  +   L +  ++   Y + KR+L NY  WR V+  ++ L + F    +KF +V YG  +   ERW  C++ V   + L +G ++++  F+K SK    EM+  +K  FQ NL    WMD  TR  A EK   +  +IG+ D ILN+TY+ E +K++ ++ ++ +FE+    +  +T + + ++  K  KR E S   TP  VNA+YSP KN I+FPAGILQ PF+   FP+S+ YGGIG  +GHE+ HGFDD G +YD  G+L  WW   T   FK K++C V+QY  ++  G  +NG  TLGENIADNGGVRL Y  Y++ +K  G  E  LP LNYTHDQLFFI+FA+LWC++ T Q     +L + H+P   RVIGTLSNF+EF++AF+CPKGS MNP  KC VW
Sbjct:  124 PCTTRACINVASKVALSLDESVDPCQDFYEFACGGWEESNLLPSGESRWSGFNALQQSNHAIMKNVLELNTTQNNSVAEKKAKIFYESCIDLEAINKRGAQPLLTMLEKV----GGWPVLNNWDESSFDFNATIQQYF-------PYSIYPFFSIGVNTDSKHSNSNIVIVGESGLSLGTRDFYVNKTI-EDDKILHAYLDYMTEVATLLGAKDRNITRFRMKEVLELEKKLAIISLPLEEMRNEEKNYHRMVLADLQ-DLAPAVDWSNLVPELFLKLANETVGTNEPVITFSRQYLRNFSDIV--YQTPKRVLGNYFGWRFVHSFVSALGQPFLEALNKFHKVQYGSNMNCVERWRRCLNTVDSVLGLAVGRLFVQKKFDKTSKSSAEEMVREIKASFQKNLPKTSWMDPVTRKKASEKCSAVEDMIGFDDKILNITYVNEKYKNLIVDPNKGHFEHHVSVVRYITVKEL-KHLRKPVKRKEWSI--TPPTVNAYYSPTKNIIVFPAGILQPPFYSSNFPKSINYGGIGIVVGHELTHGFDDQGRQYDLNGNLNNWWQKDTLAKFKKKAECMVEQYGSFNFGGAQVNGVLTLGENIADNGGVRLAYNAYQEWKKANGSLETQLPSLNYTHDQLFFISFAQLWCSVSTPQFRKHQVLVDMHSPPKARVIGTLSNFEEFSKAFSCPKGSPMNPAKKCKVW 804          

Query:  544 PCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTN------DLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQF--NEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRR-MKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGV-VGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEIN-DQTYFEN----IDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGK-EKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            PC T +C+  A ++  SL+ SV+PC DF +F CG W+   +LP G SR+S F+ +      I K +LE    + NS    KA   Y+SC++L+ IN  GA PL+T L +     GGW +L N      D N T+ ++        P    P   I V  D K+S+ NI+ +  S L L  R F  N+T  E+ KIL  + DYM +V  LL  +     +F   E+L+LE ++A      E+ R+ E  Y++M L+++Q       +W+ +V    +KL N T+  +  +I  +   L +  ++   Y + KR+L NY  WR V+  ++ L + F    +KF +V YG  +   ERW  C++ V   + L +G ++++  F+K SK    EM+  +K  FQ NL    WMD  TR  A EK   +  +IG+ D ILN+TY+ E +K++ ++ ++ +FE+    +  +T + + ++  K  KR E S   TP  VNA+YSP KN I+FPAGILQ PF+   FP+S+ YGGIG  +GHE+ HGFDD G +YD  G+L  WW   T   FK K++C V+QY  ++  G  +NG  TLGENIADNGGVRL Y  Y++ +K  G  E  LP LNYTHDQLFFI+FA+LWC++ T Q     +L + H+P   RVIGTLSNF+EF++AF+CPKGS MNP  KC VW
Sbjct:  124 PCTTRACINVASKVALSLDESVDPCQDFYEFACGGWEESNLLPSGESRWSGFNALQQSNHAIMKNVLELNTTQNNSVAEKKAKIFYESCIDLEAINKRGAQPLLTMLEKV----GGWPVLNNWDESSFDFNATIQQYF-------PYSIYPFFSIGVNTDSKHSNSNIVIVGESGLSLGTRDFYVNKTI-EDDKILHAYLDYMTEVATLLGAKDRNITRFRMKEVLELEKKLAIISLPLEEMRNEEKNYHRMVLADLQ-DLAPAVDWSNLVPELFLKLANETVGTNEPVITFSRQYLRNFSDIV--YQTPKRVLGNYFGWRFVHSFVSALGQPFLEALNKFHKVQYGSNMNCVERWRRCLNTVDSVLGLAVGRLFVQKKFDKTSKSSAEEMVREIKASFQKNLPKTSWMDPVTRKKASEKCSAVEDMIGFDDKILNITYVNEKYKNLIVDPNKGHFEHHVSVVRYITVKEL-KHLRKPVKRKEWSI--TPPTVNAYYSPTKNIIVFPAGILQPPFYSSNFPKSINYGGIGIVVGHELTHGFDDQGRQYDLNGNLNNWWQKDTLAKFKKKAECMVEQYGSFNFGGAQVNGVLTLGENIADNGGVRLAYNAYQEWKKANGSLETQLPSLNYTHDQLFFISFAQLWCSVSTPQFRKHQVLVDMHSPPKARVIGTLSNFEEFSKAFSCPKGSPMNPAKKCKVW 804          

Query:  511 VISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKI-RKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            VI N        CLT +C+  A +I +SL+ SV PC DF Q+ CG W  +  LP G SR++TF+ +      + K LLEN  F ++S    KA + Y SCLN  RI  LGA PL+  +N+T    GGW +           WD      + K +       P   + V  D K+S+ N++ +  S + +  R +  N+T   N+K+L+ + DYM ++G LL   R   + Q  +IL+ E  +A     ++++RD E  Y+KMT+S++Q       +W + +     L  + +++   ++V     L  + +L  +  + K IL+NY++W  V +  + L + F+  ++K     YG   +   RW+ C+      +   LG +++K  F+K SK    EMIN ++  F++ L    WMDD+TR  A EK D ++ +IG+ D IL+   L+E +   E+++ ++F+N+    N +     ++L K P       TP  +NA+Y P KNEI+FPAGILQ PF+    P+SL +GGIG  MGHE+ H FDD G +YD  G+L+ WW + + + FK K++C V QY++Y+++G  ING+ TLGENIADNGG++  Y  YK   K+ G+EKLLP ++ T+ QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCP G+ MNP  +C VW
Sbjct:   86 VIKNSQDPSHKICLTETCIMVAAKITESLDRSVGPCSDFYQYACGGWIKKNPLPDGRSRWNTFNSLWDQNQAVMKHLLENSTFNSSSEAERKAQRYYLSCLNEQRIEELGAQPLIDLINKT----GGWNIT--------GPWDKDNFMEVLKAVSGTYRAVPFFTVYVSADSKSSNSNVIQVDQSGVFLPSRDYYLNKTA--NEKVLNAYLDYMVELGILLGGERNSTYIQMQQILEFETILANITVPQDERRDEEKIYHKMTISDLQ-NLAPAIDWLDYLS--FGLAPVDLNETESVVVYAKEYLQMVSDLINN--TDKSILNNYMIWNLVLKTASNLDQRFENAQEKLLETLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKVTFDKDSKIVAEEMINEIRTAFKDGLDELAWMDDKTRQAAKEKADAIYDMIGFPDFILDTKELDEVYDGYEVSEDSFFQNMLNFYNFSAKVMADQLRKAPNRDQWSMTPPTINAYYLPTKNEIVFPAGILQAPFYARNNPKSLNFGGIGVVMGHELTHAFDDQGREYDKDGNLQPWWQNCSVETFKNKTECMVNQYNQYTVNGEHINGKQTLGENIADNGGLKAAYHAYKTWVKQNGEEKLLPAVDLTNHQLFFVGFAQVWCSVRTPESAHEGLITDPHSPAKFRVIGTLSNSKDFAEHFNCPTGTPMNPGKQCEVW 769          

Query:  514 ISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +++++R L   CL+ +C+  A  I  SL+  ++PC DF Q+ CG W     LP G SR++TF+ +      I K +LEN  F ++S    K  + Y SCL   RI  L   PL   + +     GGW +  N          + K +      TP   + V  D K+S+ NI+ +  S L +  R +  N+T   N K+LD +  YM  VG+LL       + Q  +IL+ E  +A     ++++RD E  YN+MT+SE+Q      F+W + +     L  + ++    ++V     L  + EL  +  +   +L+NY++W  V +  + L   F++ +DK     YG   +   RW+ C+S     +   LG++++K+ F+K SK    +MI+ ++  F+  L    WMD++TR  A EK D ++ +IG+ D IL+   L+E +   E+++  +F+N+    N +     E+L K P       TPQ VNA+Y PNKNEI+FPAGILQ PF+ P  P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK +++C V QY+ Y+++G  +NG  TLGENIADNGG++  Y  YK    K+G+EK LPG+  T++QLFF+ FA++WC+++T +S    ++++ H+P  +RVIGTLSN K+FAE FNCPKG+ MNP   C VW
Sbjct:   87 MTDRSRSL---CLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLKEQRIEELRQKPLTDLIEKI----GGWNISGNWRGENF--MSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTA--NGKVLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQ-SLAPAFDWMDYLT--FALSPLDLNDTEPVVVYGKEYLQQVSELVNN--TDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 766          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK---WDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C+  A +I +SL+ +V+PC DF Q+ CG W  +  LP G SR+STF+ +      + K LLEN  F ++S    KA   Y SCLN  RI  LGA PLV  + +T    GGW     ++  T DK    D+ K +  P    P   + V  D KNS+ N++ +  S L +  R +  N+T   N+K+L  + DYM ++G LL   K   + Q  +IL  E  +A     ++++RD E  Y+K+T++E+Q        W + +   +  + +  ++   ++V     L  + EL     + + +L+NY++W  V +  + L + F+  +DK     YG   +   RW+ C+      +   LG +++   F+K SK     MIN ++  FQ+ L    WMDDQTR  A EK D ++ +IGY D IL+   L++ +   ++++  +F+N+    N +     ++L K P       TP  VNA+Y P KN I+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + +   FK +++C V QY++Y+I+G  ING+ TLGENIADNGG++  Y  Y+   K  G+EK LP +N T+DQLFF+ FA++WC+++T +S    ++++ H+P  YRVIGTLSN  +F++ FNCP GS MN   +C VW
Sbjct:   91 SLCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKT----GGW-----NITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKT---NEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQ-TLAPAVEWLDYLSSVLSPLELNDTE--PVVVYAKEYLQQVSELINK--TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 763          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK---WDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C+  A +I +SL+ +V+PC DF Q+ CG W  +  LP G SR+STF+ +      + K LLEN  F ++S    KA   Y SCLN  RI  LGA PLV  + +T    GGW     ++  T DK    D+ K +  P    P   + V  D KNS+ N++ +  S L +  R +  N+T   N+K+L  + DYM ++G LL   K   + Q  +IL  E  +A     ++++RD E  Y+K+T++E+Q        W + +   +  + +  ++   ++V     L  + EL     + + +L+NY++W  V +  + L + F+  +DK     YG   +   RW+ C+      +   LG +++   F+K SK     MIN ++  FQ+ L    WMDDQTR  A EK D ++ +IGY D IL+   L++ +   ++++  +F+N+    N +     ++L K P       TP  VNA+Y P KN I+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + +   FK +++C V QY++Y+I+G  ING+ TLGENIADNGG++  Y  Y+   K  G+EK LP +N T+DQLFF+ FA++WC+++T +S    ++++ H+P  YRVIGTLSN  +F++ FNCP GS MN   +C VW
Sbjct:   93 SLCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKT----GGW-----NITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKT---NEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQ-TLAPAVEWLDYLSSVLSPLELNDTE--PVVVYAKEYLQQVSELINK--TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 765          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK---WDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C+  A +I +SL+ +V+PC DF Q+ CG W  +  LP G SR+STF+ +      + K LLEN  F ++S    KA   Y SCLN  RI  LGA PLV  + +T    GGW     ++  T DK    D+ K +  P    P   + V  D KNS+ N++ +  S L +  R +  N+T   N+K+L  + DYM ++G LL   K   + Q  +IL  E  +A     ++++RD E  Y+K+T++E+Q        W + +   +  + +  ++   ++V     L  + EL     + + +L+NY++W  V +  + L + F+  +DK     YG   +   RW+ C+      +   LG +++   F+K SK     MIN ++  FQ+ L    WMDDQTR  A EK D ++ +IGY D IL+   L++ +   ++++  +F+N+    N +     ++L K P       TP  VNA+Y P KN I+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + +   FK +++C V QY++Y+I+G  ING+ TLGENIADNGG++  Y  Y+   K  G+EK LP +N T+DQLFF+ FA++WC+++T +S    ++++ H+P  YRVIGTLSN  +F++ FNCP GS MN   +C VW
Sbjct:  114 SLCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKT----GGW-----NITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKT---NEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQ-TLAPAVEWLDYLSSVLSPLELNDTE--PVVVYAKEYLQQVSELINK--TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 786          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK---WDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S CLT +C+  A +I +SL+ +V+PC DF Q+ CG W  +  LP G SR+STF+ +      + K LLEN  F ++S    KA   Y SCLN  RI  LGA PLV  + +T    GGW     ++  T DK    D+ K +  P    P   + V  D KNS+ N++ +  S L +  R +  N+T   N+K+L  + DYM ++G LL   K   + Q  +IL  E  +A     ++++RD E  Y+K+T++E+Q        W + +   +  + +  ++   ++V     L  + EL     + + +L+NY++W  V +  + L + F+  +DK     YG     ++ E  ++ ++      L ++                                 WMDDQTR  A EK D ++ +IGY D IL+   L++ +   ++++  +F+N+    N +     ++L K P       TP  VNA+Y P KN I+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + +   FK +++C V QY++Y+I+G  ING+ TLGENIADNGG++  Y  Y+   K  G+EK LP +N T+DQLFF+ FA++WC+++T +S    ++++ H+P  YRVIGTLSN  +F++ FNCP GS MN   +C VW
Sbjct:   93 SLCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKT----GGW-----NITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLPSRDYYLNKT---NEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQ-TLAPAVEWLDYLSSVLSPLELNDTE--PVVVYAKEYLQQVSELINK--TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGT----KKAEGMINEIRTAFQDALDHLN--------------------------------WMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 728          

Query:  541 SPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK-WDLAKVIEDPMV---ETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRK-------EKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKY-CQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILN--VTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENST--IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS---IHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            S C T  C+ AA  + ++++ SV+PC +F Q+ CG W    ++P+ SS +S F+++  +L  + K +LE  E + +   + KA  LY SC+N   I    + PL+  ++    + G W + + D N T ++ W L + +        +  ++ + V  D+++SSR+I+++ Q S  +  R +  N+     KK+ + +  +M  + K+ +  +         +++  ++++LE EIA      E++ D    YNKMTL E+Q  +    FNWT  ++  M+ V+I ++ +  I+V     L  +  +   Y   +R + NY++W  + +R++ LS  F+ ++  +R+  +G    + RW  CV  VQ +M   +G +Y++  F  +SK  V E+I  +++ F   +    WMDDQ++  A EK   +   IGY D IL      L++ +  +  ++++YFENI         +  +KL + P +    I     VNAFYS N+N+I+FPAGILQ PFF     ++L +GGIG  +GHEI HGFDD G  +D  G++  WW++ + + F+ +S C V+QY K++     G +++G  TLGENIADNGGVR  Y+ Y    ++ G+E  LPGL+  H QLFF+ FA++WC     +  I  I ++ H+P  YRV+G+L NF+ F+EAF+C +G+ MNP +KC VW
Sbjct:   73 SVCTTPDCVTAAARLLQNMDPSVDPCQNFYQYACGGWLERHVIPETSSLHSVFNILRDELEIVLKGILET-ESERDRQAFKKAKMLYRSCMNESVIEQRDSQPLLKLID----SIGDWPVASEDWNSTAEETWRLDETLATLNAHYNKKVLLEMFVWPDDRDSSRHIIHIDQPSLGMPSRDYYLNDGN--YKKVREAYLQFMVSMAKIAREDRNLTQDDEHVWDEVKQVMELEREIANATSPAEERNDITVLYNKMTLRELQDTFGLDGFNWTRYIQGIMESVSIVVNPEEPIVVYCSPYLDKLNNILPRY--DRRTVQNYLVWMLLMERVSSLSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQSNMENAVGALYVRETFAGESKRMVGELIRKIQEAFVETVEELNWMDDQSKEKAREKAMAISEQIGYPDYILQEETQKLDQEYTHLNFSEESYFENILQNLQATAQKGHKKL-REPVDPDLWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSTEHFEEQSKCMVQQYGKFTWKLAGGQNVSGITTLGENIADNGGVRQAYKAYMKWIEREGEESYLPGLDLDHKQLFFLNFAQVWCGACRPEYAIQSIKTDPHSPLEYRVLGSLQNFEAFSEAFHCQRGAPMNPEEKCRVW 765          

Query:  529 RELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLD-KWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF---------EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYC-QQFNWTEIVRRRMKLVNITMSKDIE----IIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSIL--NVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPE-NSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS---IHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            R   + CL  + +  A  I ++++ S +PC DF ++ CG W  + I+P+ SSRY  FD++  +L  + K +LE  +       Y K+  LY SC++ ++I +L + PL+  L    G    W + T + N T + + +LA + +   V  PI+   V  D+KNS+  I+N+ Q  + L  R +  +ET+    K  + +KD++  +  +  +R++K          EQ   +   E ++A+    +E++ D    Y+KM+LSE+   Y    F+W       MK + I + KDI     I+V  P  L+ +  + +        + NY++W    + +  LS+ F+  + +FR+  YG    K RW  C S V   +S  +G +Y++  F   SK  V E++  +++ F +NL    WMDD T+  A +K   +   IGY + I+  N   ++E + D+  +   YF N          R   ++N   + N  I     VNAFYS + N+I+FPAGILQ PFF      SL +GGIG  +GHEIIHGFDD+G  +D  G+L  WW+  + + FK KS C + QY  +      G +++G NTLGENIADNGG+R  Y+ Y    K  G+E  LPGL+ +H QLFF+ FA++WC     +     I ++ H+P  +RVIG+L NF++F+EA+ C     MNP  KC VW
Sbjct:   15 RSGSACCLLNNLVFLAARILENMDPSADPCKDFYKYACGGWLKKNIIPETSSRYGVFDILRDELEVVLKAVLEKSDDAARDA-YKKSRTLYASCIDQEKIEALNSQPLLQLL----GNVNEWPIATVNWNTTQEYQKNLANLAKKYRVR-PIVNTYVGIDDKNSTAYIINIDQPGFGLPSRDYYFSETE-SYVKAREAYKDFIVAIANI--VRRDKAIPDDDVFVREQMEGLFNFEKKLAEASTPDENRTDITLIYHKMSLSELSTNYSIGNFSWLTY----MKDIFIDI-KDISSAENIVVYAPEYLIKLKTILED--ETPSTIQNYIVWMLTVEHVESLSQKFKDARAEFRKALYGTTSDKARWRSCSSYVNNILSNAVGALYVEEAFAGDSKKVVQELVKWIREVFISNLDKITWMDDATKGRARDKAFAIVERIGYPEFIVDKNDPKIDEEYADLAYSTTEYFANTLASLAFDSKRRLARINTAVDKNEWISGAAVVNAFYSSSYNQIVFPAGILQPPFFGLDQAMSLNFGGIGMVIGHEIIHGFDDSGRNFDKDGNLVDWWSAESAKNFKQKSQCIIDQYGNFQWDLAGGQNLSGINTLGENIADNGGIRQAYEAYMAWVKDNGEELPLPGLHLSHQQLFFLNFAQVWCGDYRPEYASNSIKTDVHSPGKFRVIGSLQNFEKFSEAYQCKASDAMNPRSKCHVW 707          

Query: 1093 ENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEED--QRDPESTYNKMTLSEIQ--GKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENI----DMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHY---RVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            E+ K++  +K  M  +  LL  R  +  +  ++ + E ++A     E D  +RD  + YNKM L ++        Q NW + +    ++    +S+D E++V   T +  +  L  +  +  R+LHNY+LWR V      LS  F+     F R   G     +    C++    +  ++LG ++++ +F+  SK +V +M+  +K  F   L    WMD++T+  A  K   M  +IGY + +  +  +++ +   E+N+++YF+NI    +   N ++++  +K+ +   N  +  PQ +NA+Y P  N+++FPAGILQ   ++P FP+S+ YGGIGT +GHE+ HG+DD G +YD  G+L+ WWT  +   F  +++C VK Y+ ++I+  ++NG+ TLGENIAD GG++L Y  Y+   ++ G E  L G+ YTH+QLFF+ FA+ WC  +  QS+ + +L++ H+P +Y   RV+G+ S F EF   F+C +GS M+P  KC VW
Sbjct:   20 ESLKVIKAYKVLMNKITTLLGARNAR-HKLEDVFEFEQQLANITLSESDPLRRDINNMYNKMKLRDLHHLAPAHDQINWRQFLE---QIFRKRISEDEEVVVLATTYIKKLSHLLST--TPVRVLHNYMLWRVVIVLSTHLSPPFRAALHDFSREVDGAEKEVDLERLCLAQANKYFGMVLGALFVREHFSLHSKQRVQQMVEDIKHAFDQRLEELGWMDEKTKDAARGKFQLMMDMIGYPEFLGRMDEVDKEY-GFEVNEKSYFKNILNSIEFNINVSIHKIHQKVER---NVWLLPPQTLNAYYLPTHNQMVFPAGILQPTLYDPEFPQSMNYGGIGTIIGHELTHGYDDWGGQYDRHGNLKQWWTAESYGKFLERTECVVKLYNNFTINKQNVNGKLTLGENIADMGGLKLAYHAYQKWVRENGPEPPLQGMAYTHEQLFFVAFAQNWCMKRRPQSLYLQLLTDKHSPENYSRRRVLGSASQFDEFGRVFHCRRGSPMSPQHKCSVW 519          

Query:  574 AVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTL-DKWDLAKVIE---DPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-------EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKY-CQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSIL--NVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDT-PQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS 2238
            A  + + +N + NPC +F +F CG W  +Q++P+ S  Y TF V++  L  + K+LLE      +    +KA +LY SC++ + I    + PL+  L         W + T D N T   +W L +V+           II + +  D  +S  + + + Q S  L  R F  +  K    ++ D +   M  V  +++  K          EQ   + +LE+EIA+     E++ D    +N+MTL ++Q ++    FNWT  +   +K V+I +    EI+V+ P  L  + ++  S+      +HNYV+W  + + I  LS  +Q    + +++ YGV+  + RW HCV  V   +   +G +Y+ + F +  K +V  MI  L++ F + L    WMDD+TR+ A EK   +   +GY D I+  N   L+E + D+   +  +FEN       A+    ++L +       D  P  +NAFY P+KN+I+FPAGILQ PFF  G   SL +GGIG  +GHEI HGFD+ G K+D +G+L  WWT  + + F ++S C V QYS Y+
Sbjct:    1 ATRLLEGMNPAANPCDNFYEFACGGWPKKQVIPEDSGYYGTFHVLDDHLEIVLKRLLEEAAGSGDRDAVTKAKRLYLSCMDEEAIEERDSEPLLWLLEDVLE----WPVATVDWNSTYGSQWRLEEVLAFMTSRYGNRVIIDVGIASDVNDSKSSAIYIDQPSLGLPTRDFYFD--KGYYSQVRDTYLRAMIAVATIIRADKNITDDIDFVQEQMEGVFRLEMEIAEAITPAENRTDVTKLFNRMTLLQLQQEFPLNGFNWTLFINEVLKTVDIEVEASEEILVSAPEYLEQLSDILNSHPPSD--VHNYVVWILITEVIGSLSHKYQEAIAETQKMLYGVLLARARWRHCVDYVNTALPSAVGALYVLDAFPRHGKTKVEMMIERLREAFIHTLDEMTWMDDRTRARAREKALAITTQMGYADYIVDGNNPRLDEEYADLNYEEDVHFENTLQDLEFAVKNELKRLRRTTSKQEWDIGPATINAFYHPSKNQIVFPAGILQPPFFGLGQAMSLNFGGIGMVIGHEITHGFDNFGRKFDKEGNLVDWWTAESDEDFDSRSRCLVSQYSSYT 563          

Query:  574 AVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTL-DKWDLAKVIE---DPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKF-------EQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYC------QQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSIL--NVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDT-PQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS 2238
            A  + + +N + NPC +F +F CG W  +Q++P+ S  Y TF V++  L  + K+LLE      +    +KA +LY SC++ + I    + PL+  L         W + T D N T   +W L +V+           II + +  D  +S  + + + Q S  L  R F  +  K    ++ D +   M  V  +++  K          EQ   + +LE+EIA+     E++ D    +N+MTL ++Q ++       Q FNWT  +   +K V+I +    EI+V+ P  L  + ++  S+      +HNYV+W  + + I  LS  +Q    + +++ YGV+  + RW HCV  V   +   +G +Y+ + F +  K +V  MI  L++ F + L    WMDD+TR+ A EK   +   +GY D I+  N   L+E + D+   +  +FEN       A+    ++L +       D  P  +NAFY P+KN+I+FPAGILQ PFF  G   SL +GGIG  +GHEI HGFD+ G K+D +G+L  WWT  + + F ++S C V QYS Y+
Sbjct:    1 ATRLLEGMNPAANPCDNFYEFACGGWPKKQVIPEDSGYYGTFHVLDDHLEIVLKRLLEEAAGSGDRDAVTKAKRLYLSCMDEEAIEERDSEPLLWLLEDVLE----WPVATVDWNSTYGSQWRLEEVLAFMTSRYGNRVIIDVGIASDVNDSKSSAIYIDQPSLGLPTRDFYFD--KGYYSQVRDTYLRAMIAVATIIRADKNITDDIDFVQEQMEGVFRLEMEIAEAITPAENRTDVTKLFNRMTLLQLQQEFPLNKLREQGFNWTLFINEVLKTVDIEVEASEEILVSAPEYLEQLSDILNSHPPSD--VHNYVVWILITEVIGSLSHKYQEAIAETQKMLYGVLLARARWRHCVDYVNTALPSAVGALYVLDAFPRHGKTKVEMMIERLREAFIHTLDEMTWMDDRTRARAREKALAITTQMGYADYIVDGNNPRLDEEYADLNYEEDVHFENTLQDLEFAVKNELKRLRRTTSKQEWDIGPATINAFYHPSKNQIVFPAGILQPPFFGLGQAMSLNFGGIGMVIGHEITHGFDNFGRKFDKEGNLVDWWTAESDEDFDSRSRCLVSQYSSYT 568          

Query: 1438 SKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTK-ERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFE---NIDMLTNRAMYRNF--EKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDD-TGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSI---IIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSG 2559
            S  + L NY LW  + + I  L   F++              +   RWE C+ +    ++  LG ++       + K  V +MI+ LK  F++NL    WMD++TR  A EK   +   +G  D + +V+ ++  +++ ++ +  +FE   N    T+R   R+     +  R    T+D       +Y  + N +  PAGI+Q PF++  +P  LKY GIGT +GHE+ HGFD+  GS+Y+ +G    WW + T   FK ++ C   QYS Y+     ING  TLGENIADNGG+      Y   E+++GKE+ LP LN T+ Q FF+ FA+LWC+++ K+S+   I D LS++H+P   RV G +SN   FAEAF CP G+ 
Sbjct:   46 SDPKTLTNYALWMLIQKMIPILDYRFRKAALIMAEAIDETTESPVRRWEFCMDLADKSLAYALGEIFAMKEITAKRKEDVKKMIDNLKHAFKDNLDHLPWMDNKTRLAAKEKAKNIQSAVGEDDYMEDVSNVDMFYENFKVVEGRFFETMVNFYNYTSRRTIRSMLATSMQWRAPAQTVDA-----FYYYESLNTMYIPAGIMQEPFYQDVYPMFLKYAGIGTVIGHELCHGFDNKAGSEYNVEGKQENWWENTTHNEFKLRTHCMEVQYSNYTWKERPINGTQTLGENIADNGGLHTALLAYARWEEQHGKEEPLPYLNLTNKQAFFVWFAQLWCSME-KESVEVEIEDALSDSHSPAAVRVRGMVSNSPAFAEAFTCPMGAA 423          

Query:  499 GTRRVISNQ------------NRELDSP-CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIE--DPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQ---FNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHAL-EKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
             TRRV++ Q             R   +P C T  C+ AA  I   ++ +VNPC DF Q+ CGKW  + ++P G+S++S F  V     +  KK+ +  +F +N  I+ K    Y SC N   I    A PL     +     G W  +T     T + W+  + +     +  TP+  + V  D+KNSS+NI+ +Q + + L +R++    T+ E+ K++  +K++M  +  LL             +EI + E ++A+ Y  +E  R  +  Y+KMT+ ++Q +      W + +     L +  +  D  ++V  PT L  + +L     + +RIL NY++W  +      LS+ ++       RV  GV      W+ CV+     +    G++Y+K +  K  K +  ++I  +K+ F +NL +  WMD+ T++ A  EK++++  LIGY D I++V  L   + ++ I  +  FEN          +  EK  K  +      TP +VNA+YS   N I FP+GILQ PFF+P FP+++ YG +G  MGHE+ HGFD  G  +D  G+L  WW +++ + F+    C V+QYS +++    ++G+ TL ENIADNGG+RL +Q ++  +K+  K+  LPGL  + DQLFF+ FA+LWC+  TK S+   +L+++H+P+  RV   +SN ++FAEA++CP  + MNP  KC VW
Sbjct:    7 ATRRVLALQIVSHSNTITSVPYRSYQNPICETKGCISAAFSILNKMDETVNPCRDFYQYACGKWLKDSVVPAGNSKWSAFHQVAEQNLRTLKKIFDRDDFASNGDIFRKVRDYYSSCTNKSIIEERDAAPL----KKLISDVGSWS-VTGGHTWTAETWNFEQALSLMHKLKSTPLFYMFVAADDKNSSQNIIQIQQAGITLSDREYY---TRNESDKVVKKYKEFMVKIATLLNGATADSTTGILMDEIFQFEKKLAEIYEPKERLRHSDKIYHKMTVEDLQ-QLAPAIPWMDYMN---NLFSTPVGHDEPVVVYTPTFLKSMSDLV--IRTDRRILANYMVWHLIKPLTTELSKPYREAALDLMRVEMGVESGAPTWKSCVTKTDTVLGYATGHLYVKQHDGKDVKEKAKQVIQSIKEAFISNLPTVTWMDEGTKTKARGEKMESVLDLIGYPDWIMDVAQLNAYYVNLVITPEMSFENHLNARRFVHQQTMEKRGKAVDRKEWHMTPVDVNAYYSLPNNYIAFPSGILQRPFFDPEFPQAMNYGAVGMVMGHELTHGFDSKGRLFDKNGNLESWWKNQSVEAFEEHVSCMVEQYSNFTVADVKVDGKQTLDENIADNGGLRLAFQAHRQWDKENEKQPRLPGLELSRDQLFFLGFAQLWCSSSTKNSMHHPLLTDSHSPDRIRVHAAVSNSEQFAEAYDCPLDTPMNPAKKCRVW 710          

Query:  589 KSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPE----FKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAK---VIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQ----------FNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMY--RNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEK--KYGKEKLLPGL-NYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            KS+NT+++PC DF Q+ CG W+++ ++P   S +S F +++    ++ KKL+ + +    +K N  +  KA   YD+C++   I  LG  PL   +      +G W  +TN  N T   WD  K   +I+  +   P   + V  D K+S++ ++    S  ++ R+ +   T   + KI   ++  M  + + L    E   +  E+ +LE+E+AK       QR   S  +   LS+++     +           N T+ +     L +  + +D E++V     ++++  +F +  + KRI+ NY++W   Y   + LS++F+ +  ++R    G  G   RW+ C S V     + +G +++   F K+SK     MI  ++  F +NL +  WMD++TR  A EK + +   IGY D I N T LE  +  + ++   YF N      R  Y  +N ++L K  + +     P  VNA+YS   N+I+FPAGILQ+PF+E   P SL YGGIG  +GHEI HGFDD G K++  G+L  WWT+ + + FK K+DC VKQYS Y  HG  +NG  TLGENIADNGG++ ++Q Y+  +K     +EK LPGL   +HDQLFF++FA++WC+    ++ I  I +  H+P   RVIG+LSN  EFAEA+ CP GS MNP DKC VW
Sbjct:    2 KSMNTTIDPCDDFYQYACGGWETKNLIPDTRSSWSQFRILSNRNEELLKKLINSKDIRDKYKDNPAVM-KAFDYYDACMDEKLIEKLGQQPLQDLIK----MFGSWN-VTNK-NWTEADWDFMKTFVMIQRDLSIAPWFNMFVGTDLKDSTKTVIVFDQSGTILSREAMLFNTT-YHAKIRTAYRRIMTSLMEKLGAGNEAEARMEEVYQLELELAKV-----KQRIQPSLIH--LLSKVRQNNQPRTLKLAPPPSFLNLTDFLGHIFNLTDYNVKQDTEVVVYAMEYMVNMSRIFAN--TPKRIVANYMMWHVAYFFASSLSKEFRDLYYEYREAITGTRGEDPRWQDCTSGVSGTFGMAIGLLFVDQTFKKESKTSAERMIKDIRNVFIDNLQNLNWMDEKTRKVAKEKAEAIRENIGYPDFIKNKTALELEYSGVRVDKTKYFWN--QYERRKFYNQKNIDELGKPVDKTKWSMNPPTVNAYYSSTDNKIVFPAGILQDPFYEGDHPNSLNYGGIGMVVGHEITHGFDDNGRKFNKDGNLLTWWTNNSIEAFKKKTDCLVKQYSSYEFHGKKLNGLQTLGENIADNGGIKQSFQAYQKWKKDNNVEEEKRLPGLEKLSHDQLFFLSFAQIWCSAYRPEAAIRAIENGVHSPGKLRVIGSLSNSNEFAEAWKCPVGSRMNPKDKCAVW 672          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAK---VIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C + SC+Q + ++ +S++ +VNPC DF  + CG W  + I P  + ++  F  +  +   +  KL+ + + +    +Y KA+  YDSC++   I  LG  PL   +      +G W ++    N T   WD           +  +P++ + V  D KNSS N++NL  S+  +  R F +N +    +K+   +K+ M ++   L        +  +I K E ++A      E   +    Y KM++ ++Q     Q +W   +    + V+  + ++ E++V     L+ + ++ +   + K+ L NY++WR V  +   LS+++++I   F    +       R E C+S +  +  + L  MY+   F  +SK    E++  ++  F   L    WMD+ T+  A EK + +   IGY D +++  +L   +K++ ++ +TYF N   +      RN+ KL K  + +     P  +NA+YS N+N+++FPA +LQ PF+   +PR++ YGGIGT M HE+ HGFD TG  Y+  G+   WWTD+T Q F  KS C V+QY  ++ HG  ++G+ TL ENIADNGGV+  ++ Y+    ++G E  LPG+  T++Q+FF  FAR WC + + ++  + +  + H P  +RV G+L NFK+FAE F CP GS MNP  +C VW
Sbjct:   50 CWSPSCIQTSADLLRSIDPNVNPCDDFYGYACGGWIKKNIRPAKNPKWDQFSKLTEENNALMNKLINSRQIR---ALYGKALHFYDSCMDKAEIERLGGEPLTKLIKE----FGSWAVIDKSWNET--NWDFMTSFITAHRELAVSPLVSVWVDFDIKNSSVNVINLDQSYPGISHRAFTRNSST--YRKMRHAYKELMVNLTMTLGGDSHSLREMEDIYKFEKKLANIL---EPYVEGNKKYRKMSIRKLQNATGPQIDWMRFLTGVFRGVDYKIMEEEEVVVYAYDYLVKLAKILEK--TPKKTLANYIMWRVVKIQYVQLSKEYRKIFKNFYIRAFNFWRESPREEVCLSALSENFGMPLSKMYLDRRFKGKSKKLATEIVENIRDVFIARLKDITWMDNVTKHVAEEKAEYLLENIGYPDYVMDSKHLASLYKEVPVDPKTYFLNQVYVRRNDNLRNYAKLGKPFDKTEWPFPPTMLNAYYSYNENKMVFPAAMLQAPFYYASYPRAVNYGGIGTIMAHELTHGFDVTGKDYNKYGNNIKWWTDKTIQNFYNKSQCLVEQYGNFTFHGGLVDGKLTLSENIADNGGVKQAFEAYQSWVSRHGPEPRLPGMMLTNEQIFFFAFARNWCGMFSPEAGKLSLKWDEHAPMPWRVNGSLKNFKKFAEHFKCPVGSPMNPEKRCAVW 719          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKL----YDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVI-----EDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQF-NEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFK---DIEINDQTYFENIDMLTNRAMYRNFEKLNK--RPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEP-GFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRV--WWTDRTRQLFKTKSDCFVKQYSKYSIHG-HSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW*NSQML 2607
            C T  C   A  I  S++ SV+PC DF QFVCG W  +  +P+ SS YSTF  +NT + K  + +LE        G   K +++    Y+SC++L  I+ LG  P+   +       G W +    +      WDL++ +     +      P+  + V +D   ++R+I+ +  +   + R     E   ++ KI+  +K Y+ DVG LL+  KE  E++  EI+ LE ++A     + D+   E+ +N+MT+ ++  K    ++W + + +      I  S+  +IIV     L  + +L ++  + KR+L NYV+W  +   ++FLS+ ++ ++ ++R    G  G K+RW+ CV      +  +LG  YI+++F++ SK    +MI  ++Q F++N+ S  WMD  T+    EK D+M   +GY   +       + FK    + + +   F N   +   A  R  +KL K    E   +D PQ +NA YS N+NE+I PA ILQ PFF P G P SL +G IG+ +GHE+ HGFD+TG K++  G+L    WW+D + + F  K+ C   QYS+Y + G + +NG+ TLGENIADNGG + +Y+ Y +  KK G E   LPGLN T +QLF++ F + +C+        +  LS+ H+   +RVIGTLSN  EF++AF C   + MNP  KC VW N  +L
Sbjct:    2 CHTKDCYSVARHINDSIDFSVSPCTDFYQFVCGGWMQKNPIPRSSSTYSTFTKLNTKVEKSLRGILEE-GISAIPGASKKLMRMPSDVYESCMDLGTIDKLGDQPIRDMIKEI----GSWSLEKGWVE---KDWDLSETLLYIHKKYTSAGGPLFSVHVSDDPIKNTRHIIEIDQAGPSLSR-----EVYTDSPKIIKAYKKYIIDVGTLLR-GKEAMEKYAQEIIDLETKLANISVPDADKT--ETWFNRMTIKDLM-KEAPGYDWLDHLNKMFAPEKIKDSE--QIIVPALPYLKKMIKLIEN--TPKRVLSNYVVWNVIQDEVSFLSKPYRDVRLRYRERVLGSKGHKKRWKTCVMYTNELVGDVLGAAYIQHHFDQHSKNIARDMIKEVRQAFKDNVNSIPWMDKTTKIAVSEKADSMKDEVGYPAYLKGGKKFIKRFKKYKGVTMKNNALFANRIAILKMAHKRMLKKLRKPVDKEEWPMD-PQTINAMYSFNENEMIIPAAILQPPFFYPKGSPSSLSFGAIGSILGHEMTHGFDNTGRKFNKNGELTTSNWWSDGSLKGFDEKAKCIENQYSQYKVDGKYPLNGKLTLGENIADNGGFKSSYRAYHNWLKKKGDETWSLPGLNLTSEQLFYVGFGQAYCSNSRSTEQYLATLSDRHSEEKFRVIGTLSNSYEFSKAFGCRPEAPMNPVTKCSVWSNDGLL 686          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEF----KTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD----LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLD-ICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDT-PQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDL-RVWWTDRTRQLFKTKSDCFVKQYSKYSIHG-HSINGENTLGENIADNGGVRLTYQVYKDLEKKYG-KEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C    C Q A  IR +++T   PC DF +F CG W  +  +P+  + +STF  V+ D+    ++LLE P +      N  +  KA   Y SC++   I  LG  PL+  + +     G W  L ND +   +KWD    L K+       +P   + V  D  NS+R+++ +  S L ++R+       PE   ++D + +YM  V  LL I+    ++  +I+  E ++A      ED+ D    Y ++ L  +  K    F W + ++   +  ++T   D ++++  P+  L  + ++ K   + K +L NYV+W+ +  +I+ LS+ F++ +  F     GV   + RW  C SI   ++ + LG +Y++  FN+ +  ++  MI  +K  F+  +  + W+DD+T  +  +K D +   IGY + +L    L++ FK ++I  +T+F N   +     +R   KL K  +       PQ +NA Y   +NEI    G L+  F       SL YG +G+ +GHE+ HGFD+TG K+D  GD+ + WW+  +   FK ++ C   QYSK+ I   + ++G  TL ENIADNGG +L+Y  Y    K  G +E++LPGL YT++QLFFI +A+ +C+    ++  I  LS+ H+P  +RVIGTLSN +EF++AF CP GS MNP  KC VW
Sbjct:    2 CQEPECQQIATLIRDAIDTDTPPCKDFFKFSCGNWVRKHPIPRSYNDFSTFTKVSKDIEDQLRELLETPSYIETLPENQAL-RKAKDFYRSCMDTKTIERLGTRPLMKLIRQ----LGSWS-LCNDKSWNKEKWDAYDVLRKLQSTYYPASPFFSVEVTNDHLNSTRHLIKVDQSGLSLQREIYFKH--PE---MVDTYVEYMAKVATLLGIKGNATKEMRKIVDFETKLANITTSAEDKAD--GIYRRIKLHHLI-KLVPGFPWLKHMQAIFRGAHVT---DADVVLATPSTYLSKMNDIIKE--TPKELLSNYVVWQMIRDKISLLSKPFRKARAVFNHKISGVKEQEPRWRTCTSITNDNLGVPLGTLYVRKYFNESTVGKIQLMIQEIKDTFKERVKEHEWIDDKTTQYVFQKADALRSKIGYANYVLRPIILKKRFKSLKIGKKTFFSNNVNVDKWVRHRLVGKLRKAVDKEKWPMFPQTINAMYQFYENEIGGGRGCLRRVFLALALALSLSYGAVGSIIGHEMTHGFDNTGRKFDKNGDIVQEWWSKSSLTNFKNRAQCIADQYSKFKIQNKYPLSGVVTLDENIADNGGTKLSYNAYHRWLKDNGNQEQVLPGLKYTNEQLFFIGYAQEYCSHARPKTEYIASLSDIHSPPKFRVIGTLSNMEEFSDAFKCPPGSPMNPKKKCEVW 676          

Query:  508 RVISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWD------LAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEK-FEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLD-ICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTID-TPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            R  S+  R L   CL+ +C+  A +I ++++ SV+PC DF QF CG W  +  LP G SR+STF+ +      + K LLEN  F  +S    K    Y SCLN  RI  LGA PL+  + +     GGW M           WD      + KV+  P    P   + V  D KNS+ N++ +  S L +  R +  N+T   N+K+L  + DYM ++G LL   K     Q  +IL+ E  +A     ++ +RD E  Y+K+T++E+Q       +W E +   +  + +    D E +V      L  + EL     + + +L+NY++W  V + +  L + F+  +D+     YG   +   RW+ C+      +   LG +++K  F+K SK    EMIN ++  F+  L    WMD+QTR  A EK D+++ +IG+ + IL+   L++ +   E++D ++F+N+    N +     ++L K P       TP  VNA+Y P KN I+FPAGILQ PF+    P++L +GGIG  MGHE+ H FDD G +YD +G+LR WW + + + F+ +++C ++QY++Y+++G  +NG+ TLGENIADNGG++  Y  Y+   ++ G+EK LP +N T+DQLFF+ FA++WC+++T +S    ++++ H+P  YRVIGTL+N  +F+  F CP+G+ MN    C VW
Sbjct:   82 RFSSDSGRGL---CLSEACITVASQIVEAMDRSVDPCQDFYQFACGGWMRKNPLPDGRSRWSTFNSIWGQNQALLKHLLENGTFNGSSEAERKTQSYYLSCLNTQRIEELGAQPLIDLITKI----GGWNMT--------GPWDKDNFMEVLKVVSGPYRAQPFFSVGVSADPKNSNSNVVQVDQSGLFLPSRDYYLNKTA--NEKVLAAYLDYMVELGMLLGGEKSSTLVQMQQILEFETALANITVPQDQRRDEEKIYHKVTIAELQA-LAPAVDWLEFLTSSLSPLELN---DTEPVVLYAREYLQQVSELINK--TDRSLLNNYMMWTLVQKSVATLDQRFENAQDRLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKLSKEIAEEMINEIRSAFKQALDRLSWMDEQTRKAAKEKADSIYDMIGFPEFILDPKELDDVYDGYEVSDDSFFQNMLNFYNFSARVMADQLRKTPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAHDHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNSSVEAFRVRTECMMEQYNRYTVNGEHVNGKQTLGENIADNGGLKAAYHAYQSWIQRNGQEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPRYRVIGTLANSPDFSRHFGCPEGTPMNSGKPCEVW 763          

Query:  511 VISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFG---AYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL--QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNE---------ILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQ-----FNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLN-KRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS---IHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            +I    ++ D  C T  C Q+A  + +++++SVNPC +F Q+ CG W  + I+P+ SSRYSTFD++  +L  I K +LE       +   +KA  LY SC N   I   G  PL+  L   F    A  GWE        T    D+   + +      ++   V  D+++S+ +I++   Q S  L+ R +    T P   +    ++ +M D+ KL  IR ++  + NE         ++ LE +IA      ED+ +P   YNKM L ++   +  +     F+W+    + M  VNI +S   +II  +P     +  +   Y   KR L NY++WR     +  LS  ++  +  FR+   G       W  C   V  +M   +G +Y++  F+++SK  + EMI  +++ F +N+    WMD +T+  A EK   +   IGY+D+I++  +L   +KD+  N + YFENI         +   KL  K  ++  +     VNAFYS +KN+I+FPAGILQ PFF  G  +SL YGGIG  +GHEI HGFDD G  YD  GDL+ WWT  + + F  +S+C V QYS +S    +G  +NG NTLGENIADNGG+R  YQ Y++  K +G+E  LPG++ +HDQLFF+ FA++WC     +  +  I  + H+P  +RV+G+L NF EFA+AF+C K S M P + C VW
Sbjct:   64 IILFATQKTDEMCTTADCTQSASRLIENMDSSVNPCDNFYQYACGGWLKKNIIPETSSRYSTFDILRDELEVILKGVLEKT-VDGEAAALTKAKTLYKSCTNESLIEQRGGAPLLDMLPDMFEWPIAVDGWE---EKYGATWRLEDVIARLNEKYGTQLLVNFFVGTDDRDSNSHIIHFDQQTSLGLLSRDYYAC-TGPY-AEACRAYEQFMIDLAKL--IRSDRGLKVNETLIREEVARVMDLERDIANATDTPEDRNNPVLLYNKMELGDLNTNFTLEVDSKVFDWSHFTAKIMDAVNINISDSEKIINYSPNYYRRLNLVLAKY--NKRDLQNYMVWRFAMNMVVGLSRAYRDTRKAFRKALSGTTSEAAVWRQCALYVNNNMDNAVGRLYVQEAFSEKSKELMEEMIKDIREVFISNMDDLSWMDAETKKAAEEKARAIRERIGYSDTIMDDEHLNNEYKDLSYNAEKYFENILQNLEYVQKKRLRKLRVKVNKDEWVTGAAVVNAFYSASKNQIVFPAGILQPPFFSKGQAKSLNYGGIGMVIGHEITHGFDDNGRNYDKDGDLKDWWTPDSTRRFLEQSNCIVDQYSNFSWELANGLHLNGNNTLGENIADNGGIRQAYQAYRNHVKDHGEEPPLPGIDLSHDQLFFLNFAQVWCGTHRPEQAVNSIKVDVHSPGKFRVLGSLQNFPEFAKAFSCNKSSYMIPDNVCRVW 769          

Query:  520 NQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKV---IEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRP-ENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            N +R     CLT  C+  A  +  +L+ SV+PC+DF  F CG W     LP+G SR+  F  +      + K LLEN   K  S    KA + Y +C+N  +I  LGA PL   ++      GGW      LN   DK +  +V   +   +  +P   + V  D KNS+ N++ +  S L L  R +  N+T   N+K L  + +++ ++G LL   +E  +    EI++ E  +A     +E++RD E  Y+KM + +++        W   +    K V +  S+   ++V     L  + +L +   + K +L+NY++ + V + ++ L + FQ  + +F  V YG   +   RW+ CVS     +   LG M++K+ F + SK    EM+  +K  F+++L    WMD +T+  A EK D ++ ++GY + I+N T L++ F D E+  + YF+N+    N +     ++L K P  N    TP  VNA+Y+P KNE++ PAGILQ PF+   +P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK ++ C V+QY  YSI+   +NG++TLGENIADNGG++  Y+ Y +  +K G+E +LP L  T+ QLFF+ FA++WC+++T +S    ++++ H+P+ +RVIGT+SN +EF++ F C   + MNP  KC +W
Sbjct:   31 NVHRRHPGSCLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISH----LGGWA-----LNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTA--NEKYLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLK-TLAPAVEWIPYLIEVFKPVPLNQSE--LVVVYAKEYLQKVSDLIEK--TNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIASEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 711          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKV---IEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWL-LMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFE-QFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGT-KERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRP-ENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            CLT  C+  A  +  +L+ SV+PC+DF  F CG W     LP+G SR+  F  +      + K LLEN   K  S    KA + Y +C+N  +I  LGA PL   ++      GGW      LN   DK +  +V   +   +  +P   + V  D KNS+ N++ +  S L L  R +  N+T   N+K L  + +++ ++G LL   +E  +    EI++ E  +A     +E++RD E  Y+KM + +++        W   +    K V +  S+   ++V     L  + +L +   + K +L+NY++ + V + ++ L + FQ  + +F  V YG   +   RW+ CVS     +   LG M++K+ F + SK    EM+  +K  F+++L    WMD +T+  A EK D ++ ++GY + I+N T L++ F D E+  + YF+N+    N +     ++L K P  N    TP  VNA+Y+P KNE++ PAGILQ PF+   +P++L +GGIG  MGHE+ H FDD G +YD  G+LR WW + + + FK ++ C V+QY  YSI+   +NG++TLGENIADNGG++  Y+ Y +  +K G+E +LP L  T+ QLFF+ FA++WC+++T +S    ++++ H+P+ +RVIGT+SN +EF++ F C   + MNP  KC +W
Sbjct:   82 CLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISH----LGGWA-----LNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTA--NEKYLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLK-TLAPAVEWIPYLIEVFKPVPLNQSE--LVVVYAKEYLQKVSDLIEK--TNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIAEEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 753          

Query:  535 LDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDK-WDLAK---VIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLM-ERQFLQNETKPENKKILDVFKDYMYDVGK-------LLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYC-QQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVT--YLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENST--IDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYS---IHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            L++ C T  C+ AA  + ++++ SV PC +F ++ CG W    ++P+ SSR+S FD++   L  + K +LE         I  KA  LY+SC+N   I    + PL+  ++    + GGW + + D N T ++ W L     ++     +  I+ + V  D+++S R+I+ +    L M  R +  N+     KK+ + +  +M  + K       L +  +  +E+  ++L+LE +IA      E+++D    YNKMT+SE+Q  +    FNWT+ ++  +  V+I   ++ E++V +   L  + ++   ++   R + NY++W+ +  R++ LS  F+  + ++R+  YG       W  CV  VQ  M   +G +Y++  F  +SK  V  +I+ ++Q +   L    WMDD ++  A EK   M   IGY D IL  +   L++ +  +  +++ YFEN+        +++ +KL + P +    I     VNAFYSPN+N+I+FPAGILQ PFF     ++L +GGIG  +GHEI HGFDD G  +D  G++  WW++ + + FK +S C V+QY  ++     G +++G +TLGENIADNGGVR  Y+ Y    +  G+E  LPGL+  H QLFF+ FA++WC     +     I +++H+P  YRV+G+L NF+ F+EAF C KGS MNP  KC VW
Sbjct:   75 LNNVCTTADCVTAAARLLQNMDKSVEPCDNFYRYACGGWLERHVIPETSSRHSVFDILRDKLEIVLKGVLEMTSEADRDAI-KKAKVLYNSCMNESLIEQRDSQPLMKLID----SVGGWPVASEDWNTTAEETWSLESTLAILTAHFHKKVILDMYVWTDDRDSQRHIIYIDQPGLGMPSRDYYFNDGN--YKKVREAYLQFMVSIAKITRDDRNLTQDEERVWEEMMQVLELETDIANATSPAEERQDVTVLYNKMTISELQSTFSLNGFNWTKFIQGVLSTVSIDTQREEEVVVYSAPYLQKLDDVLSRHSV--RTMQNYLIWQLIIDRVSSLSRRFKDARARYRKTLYGTTVEDAWWRECVRYVQSSMENAVGALYVRETFAGESKQMVSNLISKIQQAYVETLEELNWMDDASKEKAREKAMAMKEHIGYPDHILEESNQKLDQEYAHLNFSEENYFENVLENLKSEAHKSLKKL-REPVDPDLWIIGAAVVNAFYSPNRNQIVFPAGILQPPFFSKHQHQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMLNWWSNYSAEHFKDQSQCMVQQYGNFNWKLAGGQNVSGISTLGENIADNGGVRQAYKAYLKWMEMEGEEPRLPGLDMNHRQLFFLNFAQVWCGAYRPEYASQSIKTDSHSPLEYRVLGSLQNFEAFSEAFQCQKGSPMNPELKCRVW 769          

Query:  256 MSSDQYSRSIELGEVTPDIKIDGNIENQKMVASNSPEIDPIFKGLRSEHRKMSWEKXXXXXXXXXXXXXXXXXXXXXSSTMGTRRVISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            MSSDQYSRSIELGEVTPDIKIDGNIENQKMVASNSPEIDPIFKGLRSEHRKMSWEKILLILIFIITIILLLLLVVLLSSTMGTR +   QNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNS IYSKAVKLYDSCLNLDRINSLGA PLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMINLLKQKFQNNLLSNVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW
Sbjct:    1 MSSDQYSRSIELGEVTPDIKIDGNIENQKMVASNSPEIDPIFKGLRSEHRKMSWEKILLILIFIITIILLLLLVVLLSSTMGTRSI---QNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSDIYSKAVKLYDSCLNLDRINSLGAIPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMINLLKQKFQNNLLSNVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 775          

Query:  256 MSSDQYSRSIELGEVTPDIKIDGNIENQKMVASNSPEIDPIFKGLRSEHRKMSWEKXXXXXXXXXXXXXXXXXXXXXSSTMGTRRVISNQNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMV 2586
            MSSDQYSRSIELGEVTPDIKIDGNIENQKMVASNSPEIDPIFKGLRSEHRKMSWEKILLILIFIITIILLLLLVVLLSSTMGTR +   QNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNS IYSKAVKLYDSCLNLDRINSLGA PLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMINLLKQKFQNNLLSNVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMV
Sbjct:    1 MSSDQYSRSIELGEVTPDIKIDGNIENQKMVASNSPEIDPIFKGLRSEHRKMSWEKILLILIFIITIILLLLLVVLLSSTMGTRSI---QNRELDSPCLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSDIYSKAVKLYDSCLNLDRINSLGAIPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMINLLKQKFQNNLLSNVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKRPENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKLLPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMV 774          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSE-QILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNLQLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSY---ASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNF---EKLNKRPENSTIDT----PQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C T  C +   E+ K +N S +PC DFS ++CG      +ILP G + +++F  + + +    K LLE       S   +KA   Y SC+N +  N + + P++  + +       +E+            +L K+++  +  +    I V +D  N   NILN+    L++    L+N     +K+I+  +  YM  V  +L I K      +EILKL I +AK  P   DQ DPE   NK+++  +Q K+    +W  ++   ++  +  + +D +++  +      + ++ K Y   + KK+IL   + W  +   +   S+      ++F    +G+ G +E W+ CV I    +  I+GNM++K+ F    K  +  MI+ +K   ++ + +  WMD  T+S ALEK+  +   IGY DS+++ TYL + +  IE+     F+N  +L N   ++ F   E L    E  + D      QEVNA+Y+P  NEI+FPA IL+ PF++ G P +  YGGIG  +GHEI+HGFD  GSK+DSKG LR WWT  +R  + +K+ C + QY+ Y I+   +    T+GE+IADN G+R++Y  +    K   +EKL LPG++ + +QLFF+   R WC++ TK  I   +  + H+   YR+ G +SN  EF++ FNC +   MN   KC+VW
Sbjct:   24 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVFRILP-GQNSFNSFTQIRSSVTTTLKDLLEKQSTANRSQPQTKAAIYYQSCMNKESRNKI-SHPIILEVAKEISNGNDFEL------------NLIKLLKSGL-GSRFFSIEVAQDAANPEYNILNIGKPTLILSEGTLRNFE--SSKEIIASYIKYMKKVLNILGISKNYENVIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRNMQQKF-PSISWIRVINEVLENSDKKLKEDDKLVAFSLEYFDSLIKILKEYLGDSQKKQILQRDLEWAVISSLVPLGSDALIEANEEFMSEGFGIKGKQEEWKKCVQITSSTLQEIVGNMFVKSQFQPSQKKDIELMIDYIKAALKDVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPIEMT----FKN--LLGNYINFQEFAREEYLKAVGEKISPDEWAMGSQEVNAYYNPTSNEIVFPAAILRFPFYDIGLPITYNYGGIGMVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGIRMSY--FAANSKLEVREKLTLPGVDLSPEQLFFVGVGRTWCSIVTKSFIDERLKGDVHSVWKYRINGPMSNMPEFSKLFNCDRNKKMNRLKKCLVW 690          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNLLDICELFKSYAS---KKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKR--PENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C T  C +   E+ K +N S +PC DFS ++CG       +  G + + +F  +++ +    K LLE       S   +KA   Y SC+N +  N + + P++  + +       +E+            +L K+ +  +  +    I V +D  N   NILN+ + +++L+E     +E+   +K+I+  +  YM  V  +L I K      +EILKL I +AK  P   DQ DPE   NK+++ ++Q K+    +W  ++    +   I + +D +++  +   L    ++ K Y     K+ IL   + W  +   ++  S       ++F     GV G +E W+ CV +    +  I+GNM++K+ F    K  +  MI+ +K   +N + +  WMD  T+S ALEK+  +   IGY DS+++ TYL + +   E++   +  N       +     + + K+  P+   + + QEVNA+Y+P  NEI+FPA IL+ PF++ G P +  YGGIG  +GHEI+HGFD  GSK+DSKG LR WWT  +R  + +K+ C + QY+ Y I+   +    T+GE+IADN G+R++Y  +    K   +EKL LP +  + +QLFF+   R WC + TK  I   +  + H+   YR+ G +SN  EF++ FNC +   MN   KC+VW
Sbjct:   24 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKI-SHPIILEVAKEISNGNDFEL------------NLIKLFKSGL-GSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSES--SSKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKF-PSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGS-QEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSY--FAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 691          

Query:  547 CLTVSCLQAAVEIRKSLNTSVNPCYDFSQFVCGKWQSEQILPKGSSRYSTFDVVNTDLFKIQKKLLENPEFKTNSGIYSKAVKLYDSCLNLDRINSLGATPLVTYLNRTFGAYGGWEMLTNDLNPTLDKWDLAKVIEDPMVETPIIRIIVQEDEKNSSRNILNL-QLSWLLMERQFLQNETKPENKKILDVFKDYMYDVGKLLKIRKEKFEQFNEILKLEIEIAKKYPKEEDQRDPESTYNKMTLSEIQGKYCQQFNWTEIVRRRMKLVNITMSKDIEIIVTNPTNL---LDICELFKSYASKKRILHNYVLWRTVYQRINFLSEDFQRIKDKFRRVYYGVVGTKERWEHCVSIVQVHMSLILGNMYIKNNFNKQSKPQVLEMIXXXXXXXXXXXXXXVWMDDQTRSHALEKIDTMWPLIGYTDSILNVTYLEETFKDIEINDQTYFENIDMLTNRAMYRNFEKLNKR--PENSTIDTPQEVNAFYSPNKNEIIFPAGILQNPFFEPGFPRSLKYGGIGTAMGHEIIHGFDDTGSKYDSKGDLRVWWTDRTRQLFKTKSDCFVKQYSKYSIHGHSINGENTLGENIADNGGVRLTYQVYKDLEKKYGKEKL-LPGLNYTHDQLFFITFARLWCNLQTKQSIIIDILSNAHTPNHYRVIGTLSNFKEFAEAFNCPKGSGMNPTDKCMVW 2589
            C T  C +   E+ K +N S +PC DFS ++CG       +  G + +  F  +++ +    K LLE       S   +KA   Y SC+N +  N + + P++  + +       +E+            +L K+++  +  +    I V +D  N   NILN+ + +++L+E     +E+   +K+I+  +  YM  V  +L I K      +EILKL I +AK  P   DQ +PE   NK+++ ++Q K+    +W  ++    +   I + +D +++  +   L   + I +++     K+ IL   + W  + + +   S+     +++F     GV G +E W+ CV +    +  I+GNM++K+ F    K  +  MI+ +K   ++ + +  WMD  T+S ALEK+ T+   IGY DS+++ TYL + +   E++   +  N       +     + + K+  P+   +  PQ+VNA+Y+   NEI+FPA I + PF++ G P +  YGGIG  +GHEI+HGFD  GSK+DSKG LR WWT  +R  + +K+ C + QY+ Y I+   +    T+GE+IADN G+R++Y  +    K   +EKL LP +  + +QLFF+   R WC + TK  I   +  + H+   YR+ G +SN  EF++ FNC +   MN   KC+VW
Sbjct:   24 CETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDYFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKI-SHPIILEVAKEISNGNDFEL------------NLIKLLKSGL-GSRFFSIDVAQDAANPEYNILNIGKPTFVLLEGTLRDSES--SSKEIITSYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSNPEKYTNKLSIRDMQKKF-PSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDYSIKILKVYLGDRKKREILQKDLEWAVISRLVLLGSDALIEAQEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKSVIENLTWMDSNTKSSALEKLKTIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDKWAMG-PQKVNAYYNALSNEIVFPAAIFRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSY--FAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDNQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 691