Innexin

Overview
NameInnexin
Smed IDSMED30035308
Length (bp)1831
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Innexin (SMED30035308) t-SNE clustered cells

Violin plots show distribution of expression levels for Innexin (SMED30035308) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Innexin (SMED30035308) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Innexin (SMED30035308) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035308

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
prepharyngeal regionSMED30035308h1SMcG0000396 SmedASXL_010488SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
head regionSMED30035308h1SMcG0000396 OX_Smed_1.0.15056ox_Smed_v2PMID:24238224
Kao et al., 2013		whole organism asexual adult RNA-sequencing evidence
reproductive organSMED30035308h1SMcG0000396 Contig34135newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 197.593 bits (501), Expect = 3.408e-57
Identity = 122/389 (31.36%), Postives = 199/389 (51.16%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNE---KYNYRCTSKINY 1638
            DD  DKLN+  T  I+     +V+ +QYV  PI C++           Y EN+CWV  T  +    + P   +E+ +    +I YYQWVPFVL ++ + F++P ++W  +    +G ++Q +   A  A     +A+      IA  +E  L             I + +      C+  KR    V + Y  +K+LY+GN V Q++++  FLG ++  +  + +L +LL G++WE++  FPR+  C  ++R LG  ++  + QCVL +NM NEKI++FLW W  +   +S +S+ HW+        +  FIR  L   +         R  V KF   FL YDGVF +RM+S +AGD++  E++  LW  FN+   K  +  T  +N+
Sbjct:   19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFP---LEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDAL------------EIQREVTDVSGMCV-QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYG-FHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTV-QCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL-----ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQFNSTESLNH 383
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 197.593 bits (501), Expect = 3.408e-57
Identity = 122/389 (31.36%), Postives = 199/389 (51.16%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNE---KYNYRCTSKINY 1638
            DD  DKLN+  T  I+     +V+ +QYV  PI C++           Y EN+CWV  T  +    + P   +E+ +    +I YYQWVPFVL ++ + F++P ++W  +    +G ++Q +   A  A     +A+      IA  +E  L             I + +      C+  KR    V + Y  +K+LY+GN V Q++++  FLG ++  +  + +L +LL G++WE++  FPR+  C  ++R LG  ++  + QCVL +NM NEKI++FLW W  +   +S +S+ HW+        +  FIR  L   +         R  V KF   FL YDGVF +RM+S +AGD++  E++  LW  FN+   K  +  T  +N+
Sbjct:   19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFP---LEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDAL------------EIQREVTDVSGMCV-QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYG-FHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTV-QCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL-----ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDRVRKIQFNSTESLNH 383
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-1 (Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394])

HSP 1 Score: 197.593 bits (501), Expect = 1.239e-56
Identity = 119/375 (31.73%), Postives = 194/375 (51.73%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEK 1605
            DD  DKLN+  T  I+     +V+ +QYV  PI C++           Y EN+CWV  T  +    + P   +E+ +    +I YYQWVPFVL ++ + F++P ++W  +    +G ++Q +   A  A     +A+      IA  +E  L             I + +      C+  KR    V + Y  +K+LY+GN V Q++++  FLG ++  +  + +L +LL G++WE++  FPR+  C  ++R LG  ++  + QCVL +NM NEKI++FLW W  +   +S +S+ HW+        +  FIR  L   +         R  V KF   FL YDGVF +RM+S +AGD++  E++  LW  FN++
Sbjct:   19 DDFVDKLNYHYTSAIIFAFAIIVSAKQYVGYPIQCWVPAQFTDA-WEQYTENYCWVENTYYLPLTSAFP---LEYGDRRARQISYYQWVPFVLALEALCFYIPCIMWRGLLHWHSGINVQSLTQMACDARMMDADARAATVQTIAGHMEDAL------------EIQREVTDVSGMCV-QKRWANYVTLLYVFIKMLYLGNVVLQVFMLNSFLGTDNLFYG-FHILRDLLNGREWEVSGNFPRVTMCDFEVRVLGNVHHHTV-QCVLMINMFNEKIFLFLWFWYFMVAFVSAVSMFHWIIISFLPGQHMKFIRKYLRATDL-----ATDRQSVKKFVHKFLGYDGVFCMRMISAHAGDILATELIVALWHNFNDR 369
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: inx-13 (Innexin [Source:UniProtKB/TrEMBL;Acc:O44887])

HSP 1 Score: 194.897 bits (494), Expect = 4.373e-56
Identity = 124/387 (32.04%), Postives = 204/387 (52.71%), Query Frame = 1 
Query:  475 GVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRN--LVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSK 1629
            G DD  D+LN+  T ++L++    ++ +QYV +PI C++     G     Y EN+C+V  T  IS +   P +EI+    E  +I YYQWVPF+LG+Q ILF+LP L W L+  N +G  ++ ++  A +A    E+A+ +     AK+    LY++        K  S   Y            G+ +   Y  VK LY+   V Q  ++  FLG     +    +L ++L G++WE +  FPR+  C  ++R LG ++   + QCVL +NM NEK+Y+FLW W+++ GV +F++L++W  KL         I++ L + +     D N RN  ++DKF    L+ DGVF+  ++  N G + + +V+  +W  F +  + R   K
Sbjct:   15 GDDDSIDRLNYYWTPMLLVIFALTLSAKQYVGQPIQCWIPAQFTGA-WEQYSENYCFVQNTYFISPDKYIPDSEID---REGAEIGYYQWVPFILGLQAILFYLPSLFWRLMNFN-SGVALKKMLFGAKKADRVDEKARNEA----AKSTGAHLYESLTLQSRFAKYTSAFTYG-----------GSYLTYLYLFVKFLYLVQIVFQFIILNNFLGTSYTFWGL-GILSDILNGREWEESGHFPRVTMCDFEVRVLGNKHRHTV-QCVLMINMFNEKVYVFLWFWLVIVGVATFLNLVNWTRKLMFRSARKAHIKSYLQIEDNFS--DDNSRNGQILDKFVDYKLKSDGVFITHLIDNNGGSVFSHDVIVDMWDRFLQDEDNRSQKK 377
[Close]
BLAST of Innexin vs. Ensembl Celegans
Match: unc-7 (Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q03412])

HSP 1 Score: 194.897 bits (494), Expect = 5.172e-56
Identity = 121/374 (32.35%), Postives = 197/374 (52.67%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKR-IGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFN 1599
            DD  DKLN+  T  IL     +V+ +QYV  PI C++        +  Y EN+CWV  T  +      P    E       +I YYQWVPF+L ++ +LF++P +LW  +    +G ++Q ++  A  A     E K +    +A+   HM  + Q  NI  R+  S++ +SN        R  G  V + Y  +K+LY  N + Q +L+   LG    ++  + +L +L+   +WE T +FPR+  C  ++R LG  +   + QCVL +NM NEKI++FLW W + CG+++  + ++W+  +       +F+R  L +        I     + KFT +FLR DGVF+LRM+S +AG++++ E++  LW  FN
Sbjct:   19 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPR---EIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMAR---HMQDEVQLTNID-RQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYG-FSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTV-QCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFN 382
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: shakB (gene:FBgn0085387 transcript:FBtr0112571)

HSP 1 Score: 88.1965 bits (217), Expect = 2.042e-18
Identity = 86/301 (28.57%), Postives = 132/301 (43.85%), Query Frame = 1 
Query:  466 TYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPI------SYNGSTPTTEI---EWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEIT---LIFPRIAFC-LVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHW 1329
            ++V  D +  +L++ +TV+IL+    ++T RQYV  PI C  + DI      D +  +CW+  T  +          S P   I   +    +K    YYQWV F L  Q ILF+ P  LW    ++  G  I  +I   +  + S  E K+K  + +    E++ Y N                                   Y+  +LL + N +GQ++LM  F   E  +F   KV+D +   ++  +     IFPR+  C   K    GE      A C+LP+N++NEKIYIFLW W
Sbjct:   15 SHVKTDSIVFRLHYSITVMILMSFSLIITTRQYVGNPIDCVHTKDIPE----DVLNTYCWIQSTYTLKSLFLKKQGVSVPYPGIGNSDGDPADKKHYKYYQWVCFCLFFQAILFYTPRWLW----KSWEGGKIHALIMDLDIGICSEAEKKQKKKLLLDYLWENLRYHNWW------------------------------AYRYYVCELLALINVIGQMFLMNRFFDGEFITFGL-KVIDYMETDQEDRMDPMIYIFPRMTKCTFFKYGSSGEVEKHD-AICILPLNVVNEKIYIFLWFW 275
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0301860)

HSP 1 Score: 85.8853 bits (211), Expect = 9.910e-18
Identity = 86/336 (25.60%), Postives = 149/336 (44.35%), Query Frame = 1 
Query:  472 VGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGT--IPISYNGSTPT--------TEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEI---TLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNE 1440
            V +D+   ++++  TVIIL+    +VT RQY+  PI C +     GV     ++ +CW++ T  +P    G T          + +E ++  K+   YYQWV FVL  Q ILF++P  LW    ++  G  ++ ++   N  + + E   ++  I +   I ++                 N ++  AF              +F  + L   N +GQ+Y + FFL  E  ++    VL       D  I     +FP++  C                 CVLP+N++NEKIY+FLW W ++  ++S ISL++ +  +   +     +R +  L E
Sbjct:   17 VCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV-----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYH-KYYQWVCFVLFFQAILFYVPRYLW----KSWEGGRLKMLVMDLNSPIVNDECKNDRKKILVDYFIGNL-----------------NRHNFYAF-------------RFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGS-DVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVAGPKLRHLLLRARSRLAE 311
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071005)

HSP 1 Score: 85.8853 bits (211), Expect = 9.910e-18
Identity = 86/336 (25.60%), Postives = 149/336 (44.35%), Query Frame = 1 
Query:  472 VGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGT--IPISYNGSTPT--------TEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEI---TLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNE 1440
            V +D+   ++++  TVIIL+    +VT RQY+  PI C +     GV     ++ +CW++ T  +P    G T          + +E ++  K+   YYQWV FVL  Q ILF++P  LW    ++  G  ++ ++   N  + + E   ++  I +   I ++                 N ++  AF              +F  + L   N +GQ+Y + FFL  E  ++    VL       D  I     +FP++  C                 CVLP+N++NEKIY+FLW W ++  ++S ISL++ +  +   +     +R +  L E
Sbjct:   17 VCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV-----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYH-KYYQWVCFVLFFQAILFYVPRYLW----KSWEGGRLKMLVMDLNSPIVNDECKNDRKKILVDYFIGNL-----------------NRHNFYAF-------------RFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGS-DVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVAGPKLRHLLLRARSRLAE 311
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0332314)

HSP 1 Score: 85.8853 bits (211), Expect = 9.910e-18
Identity = 86/336 (25.60%), Postives = 149/336 (44.35%), Query Frame = 1 
Query:  472 VGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGT--IPISYNGSTPT--------TEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEI---TLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNE 1440
            V +D+   ++++  TVIIL+    +VT RQY+  PI C +     GV     ++ +CW++ T  +P    G T          + +E ++  K+   YYQWV FVL  Q ILF++P  LW    ++  G  ++ ++   N  + + E   ++  I +   I ++                 N ++  AF              +F  + L   N +GQ+Y + FFL  E  ++    VL       D  I     +FP++  C                 CVLP+N++NEKIY+FLW W ++  ++S ISL++ +  +   +     +R +  L E
Sbjct:   17 VCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV-----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYH-KYYQWVCFVLFFQAILFYVPRYLW----KSWEGGRLKMLVMDLNSPIVNDECKNDRKKILVDYFIGNL-----------------NRHNFYAF-------------RFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGS-DVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVAGPKLRHLLLRARSRLAE 311
[Close]
BLAST of Innexin vs. Ensembl Fly
Match: Inx2 (gene:FBgn0027108 transcript:FBtr0071006)

HSP 1 Score: 85.8853 bits (211), Expect = 9.910e-18
Identity = 86/336 (25.60%), Postives = 149/336 (44.35%), Query Frame = 1 
Query:  472 VGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGT--IPISYNGSTPT--------TEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEI---TLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNE 1440
            V +D+   ++++  TVIIL+    +VT RQY+  PI C +     GV     ++ +CW++ T  +P    G T          + +E ++  K+   YYQWV FVL  Q ILF++P  LW    ++  G  ++ ++   N  + + E   ++  I +   I ++                 N ++  AF              +F  + L   N +GQ+Y + FFL  E  ++    VL       D  I     +FP++  C                 CVLP+N++NEKIY+FLW W ++  ++S ISL++ +  +   +     +R +  L E
Sbjct:   17 VCIDNNVFRMHYKATVIILIAFSLLVTSRQYIGDPIDCIVDEIPLGV-----MDTYCWIYSTFTVPERLTGITGRDVVQPGVGSHVEGEDEVKYH-KYYQWVCFVLFFQAILFYVPRYLW----KSWEGGRLKMLVMDLNSPIVNDECKNDRKKILVDYFIGNL-----------------NRHNFYAF-------------RFFVCEALNFVNVIGQIYFVDFFLDGEFSTYGS-DVLKFTELEPDERIDPMARVFPKVTKCTFHKYGPSGSVQTHDGLCVLPLNIVNEKIYVFLWFWFIILSIMSGISLIYRIAVVAGPKLRHLLLRARSRLAE 311
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q03412|UNC7_CAEEL (Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN=unc-7 PE=1 SV=1)

HSP 1 Score: 195.282 bits (495), Expect = 6.719e-54
Identity = 121/374 (32.35%), Postives = 197/374 (52.67%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKR-IGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFN 1599
            DD  DKLN+  T  IL     +V+ +QYV  PI C++        +  Y EN+CWV  T  +      P    E       +I YYQWVPF+L ++ +LF++P +LW  +    +G ++Q ++  A  A     E K +    +A+   HM  + Q  NI  R+  S++ +SN        R  G  V + Y  +K+LY  N + Q +L+   LG    ++  + +L +L+   +WE T +FPR+  C  ++R LG  +   + QCVL +NM NEKI++FLW W + CG+++  + ++W+  +       +F+R  L +        I     + KFT +FLR DGVF+LRM+S +AG++++ E++  LW  FN
Sbjct:  139 DDFVDKLNYYYTTTILASFALLVSAKQYVGFPIQCWVPATFTDA-MEQYTENYCWVQNTYWVPMQEDIPR---EIYSRRNRQIGYYQWVPFILAIEALLFYVPCILWRGLLYWHSGINLQGLVQMACDARLMDSEIKTRTVYTMAR---HMQDEVQLTNID-RQGHSRSCFSNLQLGANCGRHCGCYVTMLYIGIKVLYSANVLLQFFLLNHLLGSNDLAYG-FSLLKDLMHAIEWEQTGMFPRVTLCDFEVRVLGNIHRHTV-QCVLMINMFNEKIFLFLWFWFLTCGIVTVCNTMYWILIMFIPSQGMSFVRKYLRVLPDHPAKPIADDVTLRKFTNNFLRKDGVFMLRMISTHAGELMSSELILALWQDFN 502
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O01393|UNC9_CAEEL (Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN=unc-9 PE=1 SV=1)

HSP 1 Score: 185.267 bits (469), Expect = 1.729e-51
Identity = 121/369 (32.79%), Postives = 195/369 (52.85%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLW 1587
            DD+ DKLN+  T  I+ V   +V+ +QYV  PI C++        +  Y EN+CWV  T  +  +   P     + E E  +I YYQWVPFVL ++ +LF++P ++W L+   Q+G  +Q ++  A  +     E++ +    IA  +E  L+          +++S N        I ++  G +V   Y +VK+LY  N VGQ++L+  FLG  S  +   +VL++L+ G++WE +  FPR+  C  +++ LG  +   + QCVL +NM NEKI++FLW W  L    +  SL +W+Y          F+   L     I+ Y +     + +F   FLR DGVFLLRM++ +AG++   E+   LW
Sbjct:   21 DDIIDKLNYYYTTAIITVFAILVSAKQYVGFPIQCWVPATFTE-PMEQYTENYCWVQNTYFLPLHDYIPHN---YAERENRQIGYYQWVPFVLALEALLFYVPTIVWRLLSW-QSGIHVQSLVQMACDSRLLDLESRNRALQTIATNVEEALHVKH-------QVMSGNRLKLLNLIICTRSSGAAVTFLYISVKILYTVNIVGQIFLLNTFLGNRSKWYGL-QVLNDLMNGREWEESGHFPRVTLCDFEVKVLGNVHRHTV-QCVLMINMFNEKIFLFLWFWYFLLAGATLCSLFYWIYISVVPSRQLNFVGKYL---TGIEGYKMVDSQSLRRFVFHFLRQDGVFLLRMVATHAGELPCYELAKTLW 372
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|O61715|INX19_CAEEL (Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=inx-19 PE=1 SV=2)

HSP 1 Score: 186.422 bits (472), Expect = 3.179e-51
Identity = 123/400 (30.75%), Postives = 207/400 (51.75%), Query Frame = 1 
Query:  475 GVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSA--NQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWM-------------YKLGQMQNNSTFIRTQLLLN----EKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYR 1617
            G DD  D+LN+  T +IL VC  V++ +QY   PI C+++      ++ +Y+E++CW+  T  I    + P      +E +   I YYQWVPF+L  + ++F LP + W L C  Q+G +IQ +I +A   QA+    + ++ +       ++++  Q+    I  R  I++  +S           G  + I +   KLLY  N V Q  ++   L    F F G++VL+++ AG+ W  T  FPR+  C  ++R+L   N   + QC L +N++NEK++ FLW W M+  +I+  S ++W+              K  Q+  +S F + Q        E++        +L+D F   FL+ DGV +LRM+S +AGDM+  ++V +LW  F E+ N+R
Sbjct:   35 GDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPH-SRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQ---IGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDGQALLDASDRQKAVEAITTNFVDNLDLQSPNGRIRARGWIARIKFSRFL-------SGQCLSILHSFTKLLYSMNVVAQFLILNACLKSSDFLFFGFQVLNDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTV-QCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEFKKLQKFEKDATVERLYTVIAFAPHLLDTFVSDFLKSDGVLMLRMISNHAGDMIVVQLVRNLWQEFRER-NWR 420
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|A8WVX4|INX19_CAEBR (Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=inx-19 PE=3 SV=3)

HSP 1 Score: 185.652 bits (470), Expect = 4.004e-51
Identity = 121/400 (30.25%), Postives = 207/400 (51.75%), Query Frame = 1 
Query:  475 GVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSA--NQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWM-------------YKLGQMQNNSTFIRTQLLLN----EKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYR 1617
            G DD  D+LN+  T +IL VC  V++ +QY   PI C+++      ++ +Y+E++CW+  T  I    + P      +E +   I YYQWVPF+L  + ++F LP + W L C  Q+G +IQ +I +A   QA+    + ++ +       ++++  Q+    I  R  I++  +S           G  + I Y   KLLY  N V Q +++   L    F F G++VL ++ AG+ W  T  FPR+  C  ++R+L   N   + QC L +N++NEK++ FLW W M+  +I+  S ++W+              K  Q+  +S + + Q        E++        +L+D F   FL+ DG+ +LRM+S +AGDM+  ++V +LW  + E+ N+R
Sbjct:   19 GDDDAVDRLNYYYTPLILAVCCLVISAKQYGGTPIECWVNPH-SRESMEEYIESYCWIQNTYWIPMYENVPDDHTAREEKQ---IGYYQWVPFILIAEALMFSLPCIFWRL-CSFQSGLNIQTLINAACDAQALLDYSDRQKAVEAITCNFVDNLDLQSPNGRIRARGWIARIKFSRFL-------SGQCISIVYSFTKLLYSVNVVAQFFILNACLKSSEFVFFGFQVLSDIWAGRPWTETGHFPRVTLCDFEVRYLANLNRYTV-QCALLINIINEKVFAFLWCWYMILAIITTCSFIYWIANSFIHSEKVDYVMKFIQIAESSEYKKLQKFEKDATVERLYTVIAFAPHLLDSFVSDFLKSDGILMLRMISNHAGDMIVVQLVRNLWQEYRER-NWR 404
[Close]
BLAST of Innexin vs. UniProt/SwissProt
Match: sp|Q19746|INX3_CAEEL (Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx-3 PE=1 SV=2)

HSP 1 Score: 161.77 bits (408), Expect = 1.380e-42
Identity = 110/374 (29.41%), Postives = 187/374 (50.00%), Query Frame = 1 
Query:  481 DDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNE 1602
            DD  D+L+++ T  +L     +V+ +QYV   I C++  +  G     Y E++C++  T  I      P    + ++ +K +I YYQWVP VL +Q  +F+LP  +W+ + + Q G D   VI+ A        E + K    +   I  +L              SKN Y         K +G+   + Y  +KL+Y+ N   Q  ++  FLG E+F +  +   D L AG++W+ + +FPR+  C   +R L   +   + QCVL +NM NEKIY+F+W W +   + +FI+ L  +Y+L    +   +IR+  LL+  +  +  + + ++  F  + L+ DGV L+R +  +AG MVT E+   L+    E
Sbjct:   21 DDAVDRLSYVTTATLLAFFSIMVSCKQYVGSAIQCWMPMEFKG-GWEQYAEDYCFIQNTFFIPERSEIPG---DVEDRQKAEIGYYQWVPIVLAIQAFMFYLPSWIWSSLYK-QCGLDFPSVISEAEALRSQDSETRTKGVNKLVDFIGDIL-----------DTRSKNEYGRFYCYRFGKGLGSMTSMLYICIKLMYLANVFVQFIILNKFLGNETFLWGFHTFAD-LYAGREWQDSGVFPRVTLCDFSVRKLANVHRYTV-QCVLMINMFNEKIYLFIWFWFVFVLITTFINTLCTIYRLSFDSSRHNYIRS--LLSGPVNNFK-DEKAMIASFANNGLKQDGVLLMRFIDDHAGAMVTKEICEELFKKHGE 373
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A4S2LNY2 (Innexin OS=Opisthorchis felineus OX=147828 GN=inx PE=3 SV=1)

HSP 1 Score: 444.506 bits (1142), Expect = 7.780e-148
Identity = 209/449 (46.55%), Postives = 310/449 (69.04%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXY--KVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNIS----NGYVGSNRPSAP 1746
            M  ++F D ++KFQ  TYVGV+D ADK NFL+TV+ILL+C +VVTV+QY++KPISCY++TDIGG NLLDYVEN+CWV GTIPI+Y G  P T+  W+EMEK K+LYYQWVPFVLG+QCI+F++P ++W +IC N+TGTDIQH++ SANQAVH+ ++ + KM  ++A+T+E ML+Q++     +   I + ++  C+  + SKR+GT +   Y  +K LY+ NAVGQ+++M+ FLG    ++  +   +  ++L+GKDW+ TL+FPR+ +CLV +RH+G  +N V  QCVLPVNMLNE+IY+FLW WI+L   ++ IS+  W  ++   ++ + FI+  L L E + + D   R +V+KF + FLR DG+FLLRM+++NAGD++  ++VC LW +F  +Y +R  +       SD +     H  L   RG +           + P+AP
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLITVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQHREYRNDVWSHIRRRLWKTCSLLVVSKRLGTRLFAIYLFIKCLYLVNAVGQVFMMQTFLGLRYDNYSFFGIAIARDILSGKDWQRTLVFPRVGYCLVPVRHMGA-SNYVTGQCVLPVNMLNERIYVFLWFWIVLAATLTAISIPTWFMRMSYQKSRTCFIKKYLKLGEVLTKKD---RGMVEKFKRQFLRQDGIFLLRMIAINAGDLICSDIVCQLWKIFKTRYFFRDLTM------SDEEQEEELHVQL--SRGTVEVTDLERCASDSTPTAP 437
[Close]
BLAST of Innexin vs. TrEMBL
Match: G7YJJ0 (Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=3 SV=1)

HSP 1 Score: 442.965 bits (1138), Expect = 2.484e-147
Identity = 208/445 (46.74%), Postives = 309/445 (69.44%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXY--KVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAP 1746
            M  ++F D ++KFQ  TYVGV+D ADK NFL+TV+ILL+C +VVTV+QY++KPISCY++TDIGG NLLDYVEN+CWV GTIPI+Y G  P T+  W+EMEK K+LYYQWVPFVLG+QCI+F++P ++W +IC N+TGTDIQH++ SANQAVH+ ++ + KM  ++A+T+E ML+Q++     +   I + ++  C+  + SKR+GT +   Y  +K LY+ NAVGQ+++M+ FLG    ++  +   +  ++L+GKDW+ TL+FPR+ +CLV +RH+G  +N V  QCVLPVNMLNE+IY+FLW WI+L   ++ IS+  W  ++   ++ + FI+  L L E + + D   R +V+KF + FLR DG+FLLRM+++NAGD++  ++VC LW +F  +Y +R  +  + E   +     S     V+D        V    P+AP
Sbjct:    1 MVGSEFLDYISKFQVATYVGVEDFADKFNFLVTVMILLLCTTVVTVKQYMMKPISCYMATDIGGKNLLDYVENYCWVQGTIPIAYAGKMPETDAAWEEMEKHKLLYYQWVPFVLGLQCIMFYVPRVIWQMICYNRTGTDIQHLVLSANQAVHATDDQRTKMIQHVARTLEQMLFQHREYRNDVWSHIRRRLWKTCSLLVVSKRLGTRLFAIYLFIKCLYLVNAVGQVFMMQTFLGLRYDNYSFFGIAIARDILSGKDWQRTLVFPRVGYCLVPVRHMGA-SNYVTGQCVLPVNMLNERIYVFLWFWIVLAATLTAISIPTWFMRMSYQKSRTCFIKKYLKLGEVLTKKD---RGMVEKFKRQFLRQDGIFLLRMIAINAGDLICSDIVCQLWKIFKTRYFFRDLTMSDEEQEEEHRVQLSRGTVEVTDLERC----VSDPTPTAP 437
[Close]
BLAST of Innexin vs. TrEMBL
Match: A0A3Q0KLG6 (Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3 SV=1)

HSP 1 Score: 435.261 bits (1118), Expect = 8.502e-144
Identity = 215/454 (47.36%), Postives = 306/454 (67.40%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXX-XXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPR-DMNHSPDP 1773
            M    F D L+KFQ  TYVGV+D ADK NFL+TV++L++C ++VTV+QY++KPISCY++TD+GG NLLDYVEN+CWV GT+PI+Y+G  P T+  W E+EK K+LYYQWVPFVLG+QCILF+LP L+W +IC N+ GTD+QH++  ANQAVH+ +E + KM  ++AKT+E +L+Q +  + G+   + + +         SKR+GT +   Y  +K LY+ NA+GQ+++M+ FL    +++  G  +  N+LAG DWE+T+IFPR+ FCLV ++H G  NN   AQCVLPVNMLNE+IY+FLW WI+L   I+ IS+  W  ++   ++ + FI+  L L EK+ R D   + +V+KFT  FLR DGVFLLRM+++NAG+++  E+VC LW +F EKY YR  ++         DC    H  L   RG ++     S     PR +   S  P
Sbjct:    1 MIGTDFLDYLSKFQVATYVGVEDFADKFNFLITVMVLMLCTTIVTVKQYMMKPISCYMATDLGGKNLLDYVENYCWVQGTVPIAYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVQHLVLCANQAVHANDEQRTKMVQHLAKTLEQLLFQQREYHHGLWPRVRRRMKKWGYLFFVSKRLGTRLFGIYLFIKCLYLLNAIGQIFMMQSFLGLKSNYTLFGVAISRNILAGLDWEVTMIFPRVGFCLVPLKHFGS-NNYATAQCVLPVNMLNERIYMFLWFWIVLAATITAISIPTWFTRMSYEKSRTHFIKKYLKLGEKVSRKD---KYMVEKFTLLFLRNDGVFLLRMIAINAGELICSEIVCQLWHIFREKYFYRDLTRCK------RDCDQMHHLGLKLSRGIVNLKERCSKENKQPRLEATASAPP 444
[Close]
BLAST of Innexin vs. TrEMBL
Match: C1LF30 (Innexin OS=Schistosoma japonicum OX=6182 GN=inx PE=2 SV=1)

HSP 1 Score: 435.261 bits (1118), Expect = 9.378e-144
Identity = 210/458 (45.85%), Postives = 310/458 (67.69%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVL--DNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPR-DMNHSPDPHSS 1782
            M   +F D L+KFQ  TYVGV+D ADK NFL+TV++L++C ++VTV+QY++KPISCY++TD+GG NLLDYVEN+CWV GTIPISY+G  P T+  W E+EK K+LYYQWVPFVLG+QCILF+LP L+W +IC N+ GTD+QH++  ANQAVH+G++ + KM  ++AKT+E +L+Q +  + G+   +   ++      + SKR+GT +   Y  +K LY+ NA+GQ+++M+ FLG ++  +  + +    N+L+G DWE+T+IFPR+ FCLV ++H G  NN   AQCVLPVNMLNE+IY+FLW WI+L   I+ IS+  W  ++   ++ + FI+  L L E++ + D   + +++KFT+ FLR DGVFLLRM+++NAG+++  E++C LW +F EKY YR        ++    C    H  +   RG +      S     P+ +   S  P S 
Sbjct:    1 MIGTEFLDYLSKFQIATYVGVEDFADKFNFLITVMVLMICTTIVTVKQYMIKPISCYMATDLGGKNLLDYVENYCWVQGTIPISYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVQHLVLCANQAVHAGDDQRTKMVQHLAKTLEQLLFQQREYSDGLWPRVRHRMWKCGYLFMISKRLGTRLFGIYLFIKCLYLVNAIGQIFMMQAFLGLKTNHYTLFGITISKNILSGLDWEVTMIFPRVGFCLVPLKHFGS-NNYATAQCVLPVNMLNERIYMFLWFWIVLAATITAISIPAWFARMSYEKSRTRFIKKYLKLGEQVNKKD---KYMIEKFTRLFLRNDGVFLLRMIAINAGELICSEIICQLWHIFREKYFYRDL------LHCKRGCDDKHHLGVRLSRGIVGFKKEHSKEDKHPKLEATASAPPPSD 448
[Close]
BLAST of Innexin vs. TrEMBL
Match: G4V9H2 (Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3 SV=1)

HSP 1 Score: 433.721 bits (1114), Expect = 4.365e-143
Identity = 214/454 (47.14%), Postives = 305/454 (67.18%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXX-XXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPR-DMNHSPDP 1773
            M    F D L+KFQ  TYVGV+D ADK NFL+TV++L++C ++VTV+QY++KPISCY++TD+GG NLLDYVEN+CWV GT+PI+Y+G  P T+  W E+EK K+LYYQWVPFVLG+QCILF+LP L+W +IC N+ GTD+QH++  ANQAVH+ +E + KM  ++AKT+E +L+Q +  + G+   + + +         SKR+GT +   Y  +K LY+ NA+GQ+++M+ FL    +++  G  +  N+L G DWE+T+IFPR+ FCLV ++H G  NN   AQCVLPVNMLNE+IY+FLW WI+L   I+ IS+  W  ++   ++ + FI+  L L EK+ R D   + +V+KFT  FLR DGVFLLRM+++NAG+++  E+VC LW +F EKY YR  ++         DC    H  L   RG ++     S     PR +   S  P
Sbjct:    1 MIGTDFLDYLSKFQVATYVGVEDFADKFNFLITVMVLMLCTTIVTVKQYMMKPISCYMATDLGGKNLLDYVENYCWVQGTVPIAYSGRVPETDEGWAELEKHKLLYYQWVPFVLGLQCILFYLPRLIWQMICYNRVGTDVQHLVLCANQAVHANDEQRTKMVQHLAKTLEQLLFQQREYHHGLWPRVRRRMKKWGYLFFVSKRLGTRLFGIYLFIKCLYLLNAIGQIFMMQSFLGLKSNYTLFGVAISRNILVGLDWEVTMIFPRVGFCLVPLKHFGS-NNYATAQCVLPVNMLNERIYMFLWFWIVLAATITAISIPTWFTRMSYEKSRTHFIKKYLKLGEKVSRKD---KYMVEKFTLLFLRNDGVFLLRMIAINAGELICSEIVCQLWHIFREKYFYRDLTRCK------RDCDQMHHLGLKLSRGIVNLKERCSKENKQPRLEATASAPP 444
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070496.1 (SMESG000070496.1)

HSP 1 Score: 868.226 bits (2242), Expect = 0.000e+0
Identity = 444/491 (90.43%), Postives = 449/491 (91.45%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQ----------WVP----------------FVLGVQC--------ILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSPDPHSSIV 1788
            MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKIL ++          W P                F +   C         LFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKFFLGFESFSFLGYKVL NLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLW+MFNEKYNYRCTSK+NYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSPDPHSSIV
Sbjct:    1 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILMWKTRVICEARAIWKPQTKIRLIFWLKSIKNSFYIINGCHLFSVFSAFLFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKFFLGFESFSFLGYKVLHNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWIMFNEKYNYRCTSKMNYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSPDPHSSIV 491
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070496.1 (SMESG000070496.1)

HSP 1 Score: 671.003 bits (1730), Expect = 0.000e+0
Identity = 335/339 (98.82%), Postives = 337/339 (99.41%), Query Frame = 1 
Query:  772 ILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSPDPHSSIV 1788
             LFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKFFLGFESFSFLGYKVL NLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLW+MFNEKYNYRCTSK+NYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSPDPHSSIV
Sbjct:   50 FLFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKFFLGFESFSFLGYKVLHNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWIMFNEKYNYRCTSKMNYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSPDPHSSIV 388

HSP 2 Score: 92.0485 bits (227), Expect = 8.187e-20
Identity = 42/42 (100.00%), Postives = 42/42 (100.00%), Query Frame = 2 
Query:  626 MWRISAGFMAQFQSHTTARLRQQKSNGRKWKNLKFYIINGCH 751
            MWRISAGFMAQFQSHTTARLRQQKSNGRKWKNLKFYIINGCH
Sbjct:    1 MWRISAGFMAQFQSHTTARLRQQKSNGRKWKNLKFYIINGCH 42
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000065083.1 (SMESG000065083.1)

HSP 1 Score: 412.92 bits (1060), Expect = 3.052e-139
Identity = 210/448 (46.88%), Postives = 302/448 (67.41%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXXXXXXXXXXXY--KVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDM 1755
            M A++F D L+K Q +T VG++DL D+LNF  +VI+L+VCI +VTV+QYV KPISCYL  +IGG NLL YVEN CWV GTI +S     P+T+ EW+ +EK K+LYYQWVPF+LG+QCI+F++P L+W +IC N+TGTDIQH++ SANQAVHS +EA+ KM  Y++KT+E +LYQ++    G      + I+++  F + SKRIGT +V  Y  +KL Y+ N   QL +M+ FLGF  F+ L +  +V +N+ +G DW+ TLIFPR+++C VK+ HLG  N+ V AQCVLPVNMLNE+IY FLW WI++   ++ +S+  W+ ++  ++    FIR  L+++E+I + D     L+ KF   FLR+DG+FLL+M+SLNAGD++T E+VC LW ++   Y       +N    +DG          +   G ++N       PSAP  +
Sbjct:    1 MVASEFLDYLSKLQVSTNVGLEDLPDRLNFTFSVIVLMVCILIVTVKQYVFKPISCYLPNNIGGSNLLSYVENLCWVQGTIALSNQAKFPSTDEEWKNLEKHKMLYYQWVPFMLGLQCIMFYVPKLVWQIICYNRTGTDIQHLVVSANQAVHSSDEARSKMVSYLSKTLEQLLYQHRDHRSGKLAKFRRKIHNSVGFLMCSKRIGTWLVSSYLLLKLSYVANGFIQLIIMQKFLGFSDFNLLTFGIEVGNNIWSGTDWKTTLIFPRVSYCFVKVTHLGVINSMV-AQCVLPVNMLNERIYFFLWCWILIVLSLTILSIPIWILRILCIKYRRHFIRQFLIISEEITK-DQKENYLLAKFESQFLRHDGIFLLKMISLNAGDIITSEIVCQLWNIYKTNY-------VNRNFLNDGSDEDDDKSRTMIKLGFLNNKLADKTSPSAPSGL 439
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000070656.1 (SMESG000070656.1)

HSP 1 Score: 375.941 bits (964), Expect = 3.558e-125
Identity = 194/405 (47.90%), Postives = 266/405 (65.68%), Query Frame = 1 
Query:  553 VRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMK-XXXXXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYRCTSKINYEINSDGDCSPSAHCHLVSDRGNIS------NGYVGSNRPSAP 1746
            ++QY+LKPISCY+ST I G NLL+YVEN+CWV GTIPISY+G  P+T  EW E+ K+KILYYQWVPF+L +Q I+F++P L+W + C N TGTDI H+I SANQAVHS +EA+ KM  YIAKTIE MLYQ++    G      +++Y  C FCI SKR GT ++  YF +K LY+ N + QLY MK F    E+  F G+K++ N++ G+DW+ TL+FPR+ +C V ++++G   N ++AQCVLPVNMLNEKI+ FLW WI    ++  IS++ W+++    Q    FI   L LN+++K  D   + +V KF   FLRYDGVFLL+M+SLNAGD+V  ++VC LW +F  +Y  R     N+  +   D        +  D  N S      +  + S  PSAP
Sbjct:    1 MKQYILKPISCYIST-ISGTNLLEYVENYCWVEGTIPISYDGKIPSTNEEWAELNKYKILYYQWVPFLLSLQAIMFYIPRLIWQIFCYNTTGTDIHHLIVSANQAVHSSDEARTKMVNYIAKTIEQMLYQHRDNRNGRLARFRRSLYKICCFCIMSKRQGTRLLCMYFIIKFLYLTNCILQLYFMKCFLGLNEAGIFFGFKIMKNIINGQDWKSTLVFPRVGYCYVNVKNVGT-TNALVAQCVLPVNMLNEKIFFFLWCWIFSSAILLTISIIIWIFRTSVYQRRRGFIYRFLKLNQQLKNCD-EEKCMVVKFEHQFLRYDGVFLLKMISLNAGDIVAADIVCQLWKIFKSQYANR-----NFLSDGSDDDENHGRTLIRLDNNNHSKPSFDKSNSLQSAFPSAP 397
[Close]
BLAST of Innexin vs. Planmine SMEST
Match: SMESG000080788.1 (SMESG000080788.1)

HSP 1 Score: 349.362 bits (895), Expect = 1.787e-114
Identity = 169/420 (40.24%), Postives = 277/420 (65.95%), Query Frame = 1 
Query:  418 MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYVLKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEMEKFK-ILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQAVHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIASKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKXXX-XXXXXXXXXYKVLDNLLAGKDWEITLIFPRIAFCLVK-IRHLGERNNGVLAQCVLPVNMLNEKIYIFLWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINHRNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKY---NYRCTSKINYEINSDGD 1659
            M A +F + + +F+ +TYVG++D ADKL+FL +V +L++ + VVT++ Y+ KP++CY +T  GG N  +Y+EN+CWVHGTI        P  +++W   +  + I YYQWVPF+LG+QC +F++P ++W +IC N++GT+++ ++  AN A ++    ++     IA+TIE ML+Q++    G    + + IY+ C FC+ SK +GT +++ Y  +K LY  N +GQL++MK FL    S S  GY VL N+++GK+W  T IFPR+ +C V+ I+H+G  N  V AQC LPVNMLNEKIY+FLW W++L G+++ IS+  W Y++  +   S FI+  L++++  +R D   + +++ F + FLR+DGVFL+RM+ +NAGD++T ++V  L  ++ E Y   ++R  +     ++  GD
Sbjct:    1 MVAEEFLNLIGQFKISTYVGIEDFADKLSFLFSVTLLILSMMVVTIKSYLFKPLACYTATAPGGSNFENYLENYCWVHGTITFLPGEDIPQNDVDWARADDTRRINYYQWVPFILGLQCFMFYIPKIIWQIICYNKSGTNLESIVNDANAANNTPPVERKDKIERIARTIEDMLFQHRDYRQGNFAKLRRKIYNTCNFCVFSKHMGTWLILSYILIKFLYGLNVIGQLFIMKKFLGFNNSTSSFGYTVLSNMISGKEWHQTGIFPRVTYCYVRNIKHVGVANKYV-AQCALPVNMLNEKIYVFLWFWMVLVGIVTAISIPLWFYRMAFLSRRSKFIKRFLMMHQNYERSD---KPMINNFIEEFLRHDGVFLVRMLFINAGDIITADIVNRLLEIYKENYKHLDFRNYTAYTKALDKSGD 416
The following BLAST results are available for this feature:
BLAST of Innexin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
inx-13.408e-5731.36Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-13.408e-5731.36Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-11.239e-5631.73Innexin [Source:UniProtKB/TrEMBL;Acc:Q17394][more]
inx-134.373e-5632.04Innexin [Source:UniProtKB/TrEMBL;Acc:O44887][more]
unc-75.172e-5632.35Innexin unc-7 [Source:UniProtKB/Swiss-Prot;Acc:Q0... [more]
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BLAST of Innexin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
shakB2.042e-1828.57gene:FBgn0085387 transcript:FBtr0112571[more]
Inx29.910e-1825.60gene:FBgn0027108 transcript:FBtr0301860[more]
Inx29.910e-1825.60gene:FBgn0027108 transcript:FBtr0071005[more]
Inx29.910e-1825.60gene:FBgn0027108 transcript:FBtr0332314[more]
Inx29.910e-1825.60gene:FBgn0027108 transcript:FBtr0071006[more]
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BLAST of Innexin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q03412|UNC7_CAEEL6.719e-5432.35Innexin unc-7 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|O01393|UNC9_CAEEL1.729e-5132.79Innexin unc-9 OS=Caenorhabditis elegans OX=6239 GN... [more]
sp|O61715|INX19_CAEEL3.179e-5130.75Innexin-19 OS=Caenorhabditis elegans OX=6239 GN=in... [more]
sp|A8WVX4|INX19_CAEBR4.004e-5130.25Innexin-19 OS=Caenorhabditis briggsae OX=6238 GN=i... [more]
sp|Q19746|INX3_CAEEL1.380e-4229.41Innexin-3 OS=Caenorhabditis elegans OX=6239 GN=inx... [more]
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BLAST of Innexin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2LNY27.780e-14846.55Innexin OS=Opisthorchis felineus OX=147828 GN=inx ... [more]
G7YJJ02.484e-14746.74Innexin OS=Clonorchis sinensis OX=79923 GN=inx PE=... [more]
A0A3Q0KLG68.502e-14447.36Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3... [more]
C1LF309.378e-14445.85Innexin OS=Schistosoma japonicum OX=6182 GN=inx PE... [more]
G4V9H24.365e-14347.14Innexin OS=Schistosoma mansoni OX=6183 GN=inx PE=3... [more]
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BLAST of Innexin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Innexin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000070496.10.000e+090.43SMESG000070496.1[more]
SMESG000070496.18.187e-2098.82SMESG000070496.1[more]
SMESG000065083.13.052e-13946.88SMESG000065083.1[more]
SMESG000070656.13.558e-12547.90SMESG000070656.1[more]
SMESG000080788.11.787e-11440.24SMESG000080788.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035308 ID=SMED30035308|Name=Innexin|organism=Schmidtea mediterranea sexual|type=transcript|length=1831bp
CTCTTCCGATCTGTCACATCTGGATATTGTCTCAGCACAAATTTTCGAGG
CAAAATAAAAGATTTACCAACTCCTATGAAGTGCAAAAATCCTCACCTTA
ACTCGAACCAATTAAGACGGAAATTTCATTTGCAAATAAATTGTTTGTGT
GGGTACAATACCCAATTCGAAAGTCCCAAGAGAATTTCCCAATTGAGCTT
CCGATTGAGCACCCAATTTGCACATTCCGTCACGTGAAATCAATAAAACG
GCATGTGTTAGAATCTCCAAAAATTCTATTATTAAAAAATTTTTGAATAT
TTATATAATCCATAATTCCAATAGAAAGTTAAATCGATCGATTTTTGGAT
TTTAATTATTATTCTAAAATGGAAGAAAAACTTTTCAAAAGTTCTTTTTG
AATTATTCTAAAATGAAATGGCTGCTAACCAGTTCTTTGATTCTCTCAAC
AAATTCCAGTGGAACACATATGTAGGGGTTGATGATCTTGCGGACAAATT
GAATTTTCTATTAACCGTCATTATTTTGCTGGTCTGCATTTCGGTGGTCA
CGGTCCGTCAGTACGTACTCAAGCCGATCTCGTGCTATCTGAGCACGGAT
ATCGGAGGTGTCAATTTGCTGGATTATGTGGAGAATTTCTGCTGGGTTCA
TGGCACAATTCCAATCTCATACAACGGCTCGACTCCGACAACAGAAATCG
AATGGCAGGAAATGGAAAAATTTAAAATTCTATATTATCAATGGGTGCCA
TTTGTTCTCGGTGTTCAGTGCATTCTTTTTCATCTTCCTCATTTATTGTG
GACTTTAATCTGTCGTAACCAAACCGGAACAGATATCCAGCACGTGATTA
CTAGTGCAAATCAAGCTGTTCATTCAGGCGAAGAAGCAAAAGAAAAAATG
ACAATTTACATTGCTAAAACAATAGAACATATGCTTTATCAAAACCAGTG
CAAAAATATCGGAATAAGAAAAATGATAAGCAAAAACATTTACAGTAATT
GCGCATTTTGCATTGCCAGCAAGAGAATAGGAACCTCCGTTGTAATAGGT
TATTTCACCGTCAAGTTACTCTATATCGGGAACGCTGTTGGACAATTATA
TCTCATGAAGTTCTTCTTAGGGTTTGAGAGTTTCTCATTTCTTGGATATA
AAGTTCTGGATAATTTACTGGCGGGAAAGGACTGGGAAATCACTCTCATA
TTCCCCCGAATAGCATTTTGCTTGGTGAAAATACGCCATCTCGGAGAGAG
AAACAACGGCGTATTAGCTCAATGTGTTCTGCCGGTGAATATGCTTAACG
AAAAGATTTATATCTTTCTCTGGCATTGGATCATGCTTTGCGGAGTTATA
AGTTTCATCAGTCTGTTGCATTGGATGTATAAGTTGGGACAAATGCAAAA
CAACAGCACATTTATACGGACCCAATTGCTGTTGAATGAAAAAATTAAAC
GCTACGACATTAACCATCGAAATTTAGTAGACAAATTCACGAAATCTTTT
CTCAGATATGATGGGGTGTTTCTCCTTCGTATGATGTCACTTAATGCGGG
TGATATGGTCACTGGAGAGGTCGTTTGCCATCTTTGGGTCATGTTTAATG
AAAAGTACAATTATCGGTGTACATCGAAAATAAATTACGAAATCAACAGT
GATGGAGATTGTAGTCCATCTGCTCATTGCCATTTAGTTTCCGATAGAGG
TAACATTTCCAATGGTTATGTCGGCTCCAATAGGCCATCCGCTCCCCGTG
ACATGAATCACTCACCAGACCCCCATTCCTCGATTGTGTAGAACTTTGTA
AATACAAAATTATTTTTGTTTTATACTTAAC
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protein sequence of SMED30035308-orf-1

>SMED30035308-orf-1 ID=SMED30035308-orf-1|Name=SMED30035308-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=458bp
MAANQFFDSLNKFQWNTYVGVDDLADKLNFLLTVIILLVCISVVTVRQYV
LKPISCYLSTDIGGVNLLDYVENFCWVHGTIPISYNGSTPTTEIEWQEME
KFKILYYQWVPFVLGVQCILFHLPHLLWTLICRNQTGTDIQHVITSANQA
VHSGEEAKEKMTIYIAKTIEHMLYQNQCKNIGIRKMISKNIYSNCAFCIA
SKRIGTSVVIGYFTVKLLYIGNAVGQLYLMKFFLGFESFSFLGYKVLDNL
LAGKDWEITLIFPRIAFCLVKIRHLGERNNGVLAQCVLPVNMLNEKIYIF
LWHWIMLCGVISFISLLHWMYKLGQMQNNSTFIRTQLLLNEKIKRYDINH
RNLVDKFTKSFLRYDGVFLLRMMSLNAGDMVTGEVVCHLWVMFNEKYNYR
CTSKINYEINSDGDCSPSAHCHLVSDRGNISNGYVGSNRPSAPRDMNHSP
DPHSSIV*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
PLANA:0000419prepharyngeal region
PLANA:0002089reproductive organ
Vocabulary: INTERPRO
TermDefinition
IPR001849PH_domain
IPR000990Innexin
Vocabulary: cellular component
TermDefinition
GO:0005921gap junction
GO:0005886plasma membrane
GO:0016020membrane
GO:0016021integral component of membrane
GO:0030054cell junction
Vocabulary: biological process
TermDefinition
GO:0006810transport
GO:0006811ion transport
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableTMHMMTMhelixcoord: 35..57