Glycine receptor subunit alpha-2

Query:  123 FVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKE-----------DRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRE--------------LMNWC-TAFDRLQISHMQVHNSLDRDRL--QFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            F  L ++L  +IVF    SL +  E    RS  +    S +L +            RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA+N        ++  + PS+   +W PDLFF N K  + H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W+   ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    K    +E              +   C  A D + +      N+ +      +   ++  L I++A    KK+ K+           SR  FP  FL +N FYW+ + ++
Sbjct:    4 FNTLRLYLWETIVFF---SLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRKRRHHKEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRA----KKIDKI-----------SRIGFPMAFLIFNMFYWIIYKIV 441          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHM-QVHNSLDRDRLQF-------CHDLENLLIEKAIDSHKKVIKVRPPE--------NSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V       + +++  L  +R+  N   AF   +      + + +   R  F       C   ++ +  K  +   +V+   P E           +D  SR  FP  FL +N FYWV + +L
Sbjct:   55 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV-------SRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVA--------RNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V          R    N ++EV     RE     TA+       +Q  + +        H ++  ++ K+ D  +KV   R  +   +D  SR  FP  FL +N FYWV + +L
Sbjct:   55 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKDDEV-----RESRFSFTAYGMGPC--LQAKDGMTPKGPN--HPVQ--VMPKSPDEMRKVFIDRAKK---IDTISRACFPLAFLIFNIFYWVIYKIL 439          

Query:  123 FVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKE-----------DRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRP---PEN---------SIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            F  L ++L  +IVF    SL +  E    RS  +    S +L +            RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA+N        ++  + PS+   +W PDLFF N K  + H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W+   ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++         +   +  ++N    F   +    + + S            + + ++ A +S+       P   PE            +D  SR  FP  FL +N FYW+ + ++
Sbjct:    4 FNTLRLYLWETIVFF---SLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLN---LFQEDEAGEGRFNFSAYGMGPACLQAKDGISVKGANNSNTTNPPPAPSKSPEEMRKLFIQRAKKIDKISRIGFPMAFLIFNMFYWIIYKIV 449          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSV--------------VARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  SV+ T M+Y  +++LRQ+W DSRLA++        ++  + PS+   +W PDLFF N K    H +T  N L+R+S NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W  +  + +A G+ + +F    +     CTK    +TG+++C++ +F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V                +N   ++  E +       M  C     LQ+       +   + L       + + +K +D  K+           +D  SR  FP  FL +N FYW+ + ++
Sbjct:   56 SGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKEEDVTRESRFNFSGYGMGHC-----LQVKDGTAVKATPANPLPQPPKDGDAIKKKFVDRAKR-----------IDTISRAAFPLAFLIFNIFYWITYKII 444          

Query:  213 SLIRAEIF-SKYLKEDRPKEEEQTEVTVYMKIL--AINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGM--QISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQ-VHNSLDRDRLQFCHDLENL-LIEKAIDSHKKVIKVRPPENSI---VDVYSRFLFPALFLFYNCFYWVYF 1415
            S I A +F S Y    RP  +    V V + +L   I+ + V  MEYS  + LR+ W+D RL++      +    + V  ++   +W+PD FF N K+ Y H +  PN L+R+  +G +LYS +I++  SC M L+ +PMD Q C +D+ SY YT  ++ + W+ +  + +  G+   +  F      TT  CT  S T+TG YSCL+    L+R+   Y++  ++PS ++V+VSW++FW    ++PARV LG+ TLL M  Q+ GI+S LP VSYIKAID+W+  C+ F+ CALLE+A+ N +     +N    E K   +RE         + +I  +Q +HN +          +  + L  + ++S   +++ +   N I   VD+ SR LFP LF  +N  YW  F
Sbjct:   64 SKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQ---PDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTY-CT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHI-----ANKQGVERKARTERE---------KAEIPLLQNLHNDVPTKVFNQEEKVRTVPLNRRQMNSFLNLLETKTEWNDISKRVDLISRALFPVLFFVFNILYWSRF 454          

Query:  213 SLIRAEIF-SKYLKEDRPKEEEQTEVTVYMKIL--AINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGM--QISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQ-VHNSLDRDRLQFCHDLENL-LIEKAIDSHKKVIKVRPPENSI---VDVYSRFLFPALFLFYNCFYWVYF 1415
            S I A +F S Y    RP  +    V V + +L   I+ + V  MEYS  + LR+ W+D RL++      +    + V  ++   +W+PD FF N K+ Y H +  PN L+R+  +G +LYS +I++  SC M L+ +PMD Q C +D+ SY YT  ++ + W+ +  + +  G+   +  F      TT  CT  S T+TG YSCL+    L+R+   Y++  ++PS ++V+VSW++FW    ++PARV LG+ TLL M  Q+ GI+S LP VSYIKAID+W+  C+ F+ CALLE+A+ N +     +N    E K   +RE         + +I  +Q +HN +          +  + L  + ++S   +++ +   N I   VD+ SR LFP LF  +N  YW  F
Sbjct:   64 SKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKGDGQ---PDFVILTVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTSTTY-CT--SVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHI-----ANKQGVERKARTERE---------KAEIPLLQNLHNDVPTKVFNQEEKVRTVPLNRRQMNSFLNLLETKTEWNDISKRVDLISRALFPVLFFVFNILYWSRF 454          

Query:  270 EEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGM--QISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYA-VANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            E    V V + I  ++ + V  MEYS  +  R++W+D RLA+ NL  F +  A +  P +KK LW+PD FF   K  + H + + N  +R+ P+G ILYS +I++  SC M L+ +P+D Q C  D+ SY +T++++ + W  +  + +  G+   +  F      T  DCT  S T+TG Y CL+ + + +RQ   Y+V  + P+ +IV+VSW++FWI + S   RV LG+ TLL M T    I++ LP VSY+K +D+W+  C  FV  ALLEYA V+     R    + E   +   +R         ++L++   +V+          CH  E    E   D  ++         + +D Y+RF+ P  FL +N  YWV  L++
Sbjct:   54 EGAVNVRVNIMIRMLSKIDVVNMEYSIQLTFREQWIDPRLAYENLG-FYNPPAFLTVPHVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRLQLYPLDYQSCNFDLVSYAHTMNDIMYEWDPSTPVQLKPGVGSDLPNFILKNYTTNADCT--SHTNTGSYGCLRMQLLFKRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGVTTLLTMTTMQSAINAKLPPVSYVKVVDVWLGACQTFVFGALLEYAFVSYQDSVRQNDRSREKAARKAQRRR--------EKLEMVDAEVYQPPCT-----CHTFEAR--ETFRDKVRRYFTKPDYLPAKIDFYARFVVPLAFLAFNVIYWVSCLIM 423          

Query:  177 SLGSGSEKADQRSLIRA--EIFSKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQREL-------------MNWCTAFDRLQISHMQVHNSLDRDRLQF-CHDLENLLIEKAIDSHKKVIKVRP-------PENSI--------VDVYSRFLFPALFLFYNCFYWVYFL 1418
            +LG  S +  + ++ R   ++ + + +  RP       EV +   +  I++VS   M+Y+ D+YLRQ W D RLAW + D   S    I    + K +W PD FF N K+ + H+ T  N  +R+  +G +L S ++T+  +C M L TFP+D Q C +++ SYGY+  ++ ++W   ++++I   + ++ F + G+   +   +  S STG YS L A F+ +R +G Y++  + PS LIV++SW++FW++ ++V ARV +G+ T+L M T     +++LP+VSY+K++D+++  C   V  +LLEYA    ++ RN S    + V+     E              +N+C    + + S  +  N  D     +  +++ +   +  +D    ++ + P       P+N          VD++SRF FP  F+ ++  YW Y++
Sbjct:   39 TLGGESNENLENNVTRLLDKLIASHDRRIRPNYGGPPIEVNITAHVTTISAVSEVSMDYTLDLYLRQIWKDPRLAWES-DVEDSLTIGI---DMVKTIWTPDTFFPNEKKSFFHEATSHNSFLRIDNHGNVLRSIRLTVTANCPMSLHTFPLDRQECALEVESYGYSTKDIIYHWHGTNAVTIDENVHLAHF-TIGEH--KHIERTISLSTGNYSRLTAYFLFKRNIGFYLIQIYFPSSLIVVISWVSFWLNREAVQARVAIGVTTVLTMTTLMTSTNASLPKVSYVKSLDVFLGVCFFIVFASLLEYAAIGYLMKRNRSVPAASPVQYYETEEFFEIQCHPKFVRGAINYCDGVLKREASRKKSRNRRDSSMKNYQNNNIHHRPSDGHVDQRIPLLSMVPMPPIPFKPQNGAWGKVRPAQVDLFSRFAFPIFFVIFHIVYWTYYI 477          

Query:  207 QRSLIRAEIFSKYLKED----RPKEEEQTE--------VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSL----------KKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRD-----CTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLV 1421
            +R L   EI  + LK+     RP+    T         VTV + + +I+ +    MEYS     R+EW D RLA+   ++++      V P +           + +W+PD FF+N KE   H +  PN L+R+  NG ILYS ++++  SC M L+ +P+D Q C +D+ SY YT  ++++ W+    I    G++     S   F  +D     CT L  T+TG+YSCL+   VL+R+   Y++  ++PS ++V+VSW++FW+  DSVPARV LG+ TLL M TQ+ GI++ LP VSY KAID+W+  C+ F+  ALLE+A+ N   AR     +   ++ + Q     +                S  + R  FC     + + +  +  K+           +DV SR +FP  +  +N  YW  +L+
Sbjct:   22 KRKLKEQEIIQRILKDYDWRVRPRGMNATWPDTGGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWTDQRLAY---ERYEESGDTEVPPFVVLATSENADQSQQIWMPDTFFQNEKEARRHLIDKPNVLIRIHKNGQILYSVRLSLVLSCPMSLEFYPLDRQNCLIDLASYAYTTQDIKYEWKEKKPIQQKDGLR----QSLPSFELQDVVTDYCTSL--TNTGEYSCLRTRMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTLLTMTTQSSGINAKLPPVSYTKAIDVWIGVCLAFIFGALLEFALVN-YAARKDMTQVSQRIRQMKQLPTEGYRPL-------------SASQGRSSFCC---RIFVRRYKERSKR-----------IDVVSRLVFPIGYACFNVLYWAVYLM 416          

Query:  168 CSQSLGSGSE----KADQRSLIRAEIFSKYLKEDRPK-----EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARN-YSNNMENEVKLIVQRELMNWCTAFD---------RLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFL 1418
            CS SL + ++    + +++ L +     KY    RP      + + T V+V M + +I+ +   +MEYS  +  R++W D RL ++++     Y    ++ +    +W+PDLFF N KEG+ H + +PN  +R+ PNG +LYS +I++  +C M+LK +P+D QIC + + SYG+T ++L F W+  D + +   + +  F +  KF T  C   S T+TG+YSCLK + + +R+   Y++  ++P  ++V+VSW++FW+   +VPARV LG+ TLL M TQ  GI+++LP VSY KAID+W   C+ FV  ALLE+A+ N     + +  NM+ + + + Q  L       D         +  + H     +L++ RLQ C    ++   K  +  K  +   P  +  +DV SR  FP +F  +N  YW  +L
Sbjct:   17 CSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEK-RLQ-CE--VHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 441          

Query:  168 CSQSLGSGSE----KADQRSLIRAEIFSKYLKEDRPK-----EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSN--NMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRD-RLQFC------HDLENLLIEKAIDSHKKVIKVRPP----------------ENSIVDVYSRFLFPALFLFYNCFYWVYFL 1418
            CS SL + ++    + +++ L +     KY    RP      + + T V+V M + +I+ +   +MEYS  +  R++W D RL ++++     Y    ++ +    +W+PDLFF N KEG+ H + +PN  +R+ PNG +LYS +I++  +C M+LK +P+D QIC + + SYG+T ++L F W+  D + +   + +  F +  KF T  C   S T+TG+YSCLK + + +R+   Y++  ++P  ++V+VSW++FW+   +VPARV LG+ TLL M TQ  GI+++LP VSY KAID+W   C+ FV  ALLE+A+ N   +R+ SN  NM  E     +R+L          Q S     + LD D    F       H  + L +EK +     +   + P                 +  +DV SR  FP +F  +N  YW  +L
Sbjct:   17 CSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDNKATNVSVNMFLRSISKIDDYKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVN-YASRSGSNKANMHKENMKKKRRDLE---------QASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRQCSRSKRIDVISRITFPLVFALFNLVYWSTYL 450          

Query:  168 CSQSLGSGSE----KADQRSLIRAEIFSKYLKEDRPKEEEQTE----VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARN-YSNNMENEVKLIVQRELMNWCTAFD---------RLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFL 1418
            CS SL + ++    + +++ L +     KY    RP     T+    V + + + +I ++S  +MEYS  +  R++W D RL ++++     Y    ++ +    +W+PDLFF N KEG+ H + +PN  +R+ PNG +LYS +I++  +C M+LK +P+D QIC + + SYG+T ++L F W+  D + +   + +  F +  KF T  C   S T+TG+YSCLK + + +R+   Y++  ++P  ++V+VSW++FW+   +VPARV LG+ TLL M TQ  GI+++LP VSY KAID+W   C+ FV  ALLE+A+ N     + +  NM+ + + + Q  L       D         +  + H     +L++ RLQ C    ++   K  +  K  +   P  +  +DV SR  FP +F  +N  YW  +L
Sbjct:   17 CSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEK-RLQ-CE--VHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 440          

Query:  168 CSQSLGSGSE----KADQRSLIRAEIFSKYLKEDRPKEEEQTE----VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVAN------SVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQ----FCHDLENLLIEKAIDSH------------KKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFL 1418
            CS SL + ++    + +++ L +     KY    RP     T+    V V + + +I+ +    MEYS  +  R++W D RL ++++     Y    ++ +    +W+PDLFF N KEG+ H + +PN  +R+ PNG +LYS +I++  +C M+LK +P+D QIC + + SYG+T ++L F W+  D + +   + +  F +  KF T  C   S T+TG+YSCLK + + +R+   Y++  ++P  ++V+VSW++FW+   +VPARV LG+ TLL M TQ  GI+++LP VSY KAID+W   C+ FV  ALLE+A+ N      S  A  +  NM+ + + + Q  L       D    +   + +   R   Q      H  + L +EK +               K  +   P  +  +DV SR  FP +F  +N  YW  +L
Sbjct:   17 CSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMASQFARGGGQQKPLVRHPGDPLALEKRLQCEVHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 456          

Query:  168 CSQSLGSGSE----KADQRSLIRAEIFSKYLKEDRPKEEEQTE----VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARN-YSNNMENEVKLIVQRELMNWCTAFD---------RLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFL 1418
            CS SL + ++    + +++ L +     KY    RP     T+    V V + + +I+ +    MEYS  +  R++W D RL ++++     Y    ++ +    +W+PDLFF N KEG+ H + +PN  +R+ PNG +LYS +I++  +C M+LK +P+D QIC + + SYG+T ++L F W+  D + +   + +  F +  KF T  C   S T+TG+YSCLK + + +R+   Y++  ++P  ++V+VSW++FW+   +VPARV LG+ TLL M TQ  GI+++LP VSY KAID+W   C+ FV  ALLE+A+ N     + +  NM+ + + + Q  L       D         +  + H     +L++ RLQ C    ++   K  +  K  +   P  +  +DV SR  FP +F  +N  YW  +L
Sbjct:   17 CSASLANNAKINFREKEKKVLDQILGAGKYDARIRPSGINGTDGPAVVRVNIFVRSISKIDDVTMEYSVQLTFREQWTDERLKFDDIQGRLKY----LTLTEANRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPMNLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRF-TLEKFLTDYCN--SKTNTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVTTLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDMHKENMKKKRRDLEQASLDAASDLLDTDSNATFAMKPLVRHPGDPLALEK-RLQ-CE--VHMQAPKRPNCCKTWLSKFPTRSKRIDVISRITFPLVFALFNLVYWSTYL 440          

Query:  264 KEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQF--------CHDLENLLIEKAIDSHKKVIKVRPPENSI-------------VDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            K+     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +             +EL+     F R +  H++   + D  R  F        C   ++ +  K  +++       PPE ++             +D  SR  FP +FL +N FYW+ + ++
Sbjct:   69 KKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQH-------------KELLR----FQRRR-RHLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKG-NNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 449          

Query:  264 KEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQF--------CHDLENLLIEKAIDSHKKVIKVRPPENSI-------------VDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            K+     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +             +EL+     F R +  H++   + D  R  F        C   ++ +  K  +++       PPE ++             +D  SR  FP +FL +N FYW+ + ++
Sbjct:   71 KKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQH-------------KELLR----FQRRR-RHLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKG-NNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 451          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRL--QFCHDLENLLIEKAI---DSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K  + H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +        +L+  R         + ++ S +    +  +D    +  ++      E A+    SH+++ K+       +D  SR  FP  FLF+N FYWV + +L
Sbjct:   55 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEKGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHK-------ELLRFRRRRKKSGKEEEVRESRLSFTPNAGKDGAVPKTANNAATTPSEPAVAPGKSHEEMRKLFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 442          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQF--------CHDLENLLIEKAIDSHKKVIKVRPPENSI-------------VDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +             +EL+     F R +  H++   + D  R  F        C   ++ +  K  +++       PPE ++             +D  SR  FP +FL +N FYW+ + ++
Sbjct:   46 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQH-------------KELLR----FQRRR-RHLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKG-NNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 436          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSY--NANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 1430
            S Y    RP  +     VT  + I +  S++ T M+Y  +V+LRQ+W D RLA      +K Y  ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMDTQ C M + S+GYT+++L F W     + +A  + + +F    +     CTK    +TG+++C++ +F L+RQ+G Y++  ++PS+L V++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R Y        KL  ++E  N    F+     HM               D+    +E+A                 +D  SR +FP  FL +N FYWV + VL N
Sbjct:   59 SGYDARIRPNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLA------YKEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNFPMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQFVLKEEKDLGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVN-FVSRQYKEFFRLRRKL--RQEQRN---RFEFSPYVHMAAAMFAGLPPGHALFDIRRRFVEQA---------------KRIDTISRAVFPLSFLVFNVFYWVTYKVLRN 430          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEK-------AIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + + +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  +G +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+ N  + IA G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    K    R     C  F    +   +   S     +  C   ++ +  K       A  +H+++ KV       +D  SR  FP  FL +N FYWV + +L
Sbjct:   39 SGYDARIRPNFKGPPVNVTCNIFVNSFGSIAETTMDYRLNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQENGPVQIADGLTLPQFVLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRKRKKDRISFFVCLFFQDDDVRESRF--SFTAYGMGPCLQAKDGVNPKGPLNAPPAPKTHEEMRKVFIDRAKKIDTLSRACFPLAFLIFNIFYWVIYKIL 433          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFD----RLQISHMQVHNSLDRDRLQFCHDLENLL-IEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    STG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    +    +E  N    F      +  + +Q  + +        +   +   + K+ D  +K+   R  +   +D  SR  FP +FL +N FYW+ + ++
Sbjct:   44 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRRRRHHKEDENAEGRFSFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAKK---IDKVSRIGFPLVFLIFNTFYWIIYKIV 435          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFD----RLQISHMQVHNSLDRDRLQFCHDLENLL-IEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    STG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    +    +E  N    F      +  + +Q  + +        +   +   + K+ D  +K+   R  +   +D  SR  FP +FL +N FYW+ + ++
Sbjct:   33 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRRRRHHKEDENAEGRFSFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAKK---IDKVSRIGFPLVFLIFNTFYWIIYKIV 424          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFD----RLQISHMQVHNSLDRDRLQFCHDLENLL-IEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    STG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    +    +E  N    F      +  + +Q  + +        +   +   + K+ D  +K+   R  +   +D  SR  FP +FL +N FYW+ + ++
Sbjct:   50 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRRRRHHKEDENAEGRFSFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAKK---IDKVSRIGFPLVFLIFNTFYWIIYKIV 441          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFD----RLQISHMQVHNSLDRDRLQFCHDLENLL-IEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    STG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    +    +E  N    F      +  + +Q  + +        +   +   + K+ D  +K+   R  +   +D  SR  FP +FL +N FYW+ + ++
Sbjct:   52 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRLNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEITTDNKLLRIFKNGNVLYSIRLTLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWEEVGAVQVAEGLTLPQFILKEEKDLRYCTK--HYSTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRRRRHHKEDENAEGRFSFAAYGMGPACLQAKDGISMKGNNNNNPASSAQPVSKSPDEMRKLFISRAKK---IDKVSRIGFPLVFLIFNTFYWIIYKIV 443          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARN-----YSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPE--------NSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++     +    +N+ +     +   +    D ++ S      S     +  C   ++ ++ K  +   +V+   P E           +D  SR  FP  FL +N FYWV + +L
Sbjct:   71 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRF----SFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 470          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLD-RDRLQFCHDLENLLIE--KAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  SV+ T M+Y  +++LRQ+W DSRLA++        ++  + PS+   +W PDLFF N K    H +T  N L+R+S NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W  +  + +A G+ + +F    +     CTK    +TG+++C++ +F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++         +    +E     T   R   S   + + L  +D         N L +  K  D+ KK    R      +D  SR  FP  FL +N FYW+ + ++
Sbjct:   56 SGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE--EDVTRESRFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDADAIKKKFVDRAKR---IDTISRAAFPLAFLIFNIFYWITYKII 444          

Query:  123 FVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKE-----------DRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFD----RLQISHMQVHNSLD-RDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            F  L  +L  +IVF    SL +  E    RS  +    S +L +            RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA+N        ++  + PS+   +W PDLFF N K  + H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W+   ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    K    ++       F+     +  + +Q  + +  +               K+ +  +K+   R  +   +D  SR  FP  FL +N FYW+ + ++
Sbjct:    4 FNTLRFYLWETIVFF---SLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRKRRHHKDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPPPAPSKSPEEMRKLFIQRAKK---IDKISRIGFPMAFLIFNMFYWIIYKIV 441          

Query:  123 FVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKE-----------DRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWC----TAFDRLQISH-------MQVHNSLD-RDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            F  L  +L  +IVF    SL +  E    RS  +    S +L +            RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA+N        ++  + PS+   +W PDLFF N K  + H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W+   ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++         +   +  ++N          R   S        +Q  + +  +               K+ +  +K+   R  +   +D  SR  FP  FL +N FYW+ + ++
Sbjct:    4 FNTLRFYLWETIVFF---SLAASKEAEAARSAPKPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRRHHKSPMLNLFQDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPPPAPSKSPEEMRKLFIQRAKK---IDKISRIGFPMAFLIFNMFYWIIYKIV 449          

Query:  336 MEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFD----RLQISHMQVHNSLD-RDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            M+Y  +++LRQ+W D RLA+N        ++  + PS+   +W PDLFF N K  + H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W+   ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    K    ++       F+     +  + +Q  + +  +               K+ +  +K+   R  +   +D  SR  FP  FL +N FYW+ + ++
Sbjct:    1 MDYRVNIFLRQQWNDPRLAYNEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRKRRHHKDDEGGEGRFNFSAYGMGPACLQAKDGISVKGANNNNTTNPPPAPSKSPEEMRKLFIQRAKK---IDKISRIGFPMAFLIFNMFYWIIYKIV 358          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQF--------CHDLENLLIEKAIDSHKKVIKVRPPENSI-------------VDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +             +EL+     F R +  H++   + D  R  F        C   ++ +  K  +++       PPE ++             +D  SR  FP +FL +N FYW+ + ++
Sbjct:   46 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQH-------------KELLR----FQRRR-RHLKEDEAGD-GRFSFAAYGMGPACLQAKDGMAIKG-NNNNAPTSTNPPEKTVEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII 436          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARN-----YSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPE--------NSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++     +    +N+ +     +   +    D ++ S      S     +  C   ++ ++ K  +   +V+   P E           +D  SR  FP  FL +N FYWV + +L
Sbjct:   55 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRF----SFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHM-QVHNSLDRDRLQF-------CHDLENLLIEKAIDSHKKVIKVRPPE--------NSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V       + +++  L  +R+  N   AF   +      + + +   R  F       C   ++ +  K  +   +V+   P E           +D  SR  FP  FL +N FYWV + +L
Sbjct:   55 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV-------SRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHM-QVHNSLDRDRLQF-------CHDLENLLIEKAIDSHKKVI--------KVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+    + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V       + +++  L  +R+  N   AF   +        + +   RL F       C   ++ ++ K  +   +V+        KV       +D  SR  FP  FL +N FYWV + +L
Sbjct:   55 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV-------SRQHKELLRFRRKRKNKTEAFALEKFYRFSDTDDEVRESRLSFTAYGMGPCLQAKDGVVPKGPNHAVQVMPKSADEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKIL 454          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLD-RDRLQFCHDLENLLIE--KAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  SV+ T M+Y  +++LRQ+W DSRLA++        ++  + PS+   +W PDLFF N K    H +T  N L+R+S NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W  +  + +A G+ + +F    +     CTK    +TG+++C++ +F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++         +    +E     T   R   S   + + L  +D         N L +  K  D+ KK    R      +D  SR  FP  FL +N FYW+ + ++
Sbjct:   56 SGYDARIRPNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNFPMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFILKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHKEFLRLRRRQKRQNKE--EDVTRESRFNFSGYGMGHCLQMKDGTAVKATPANPLPQPPKDADAIKKKFVDRAKR---IDTISRAAFPLAFLIFNIFYWITYKII 444          

Query:  138 IFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEE-EQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPEN---SIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 1430
            + LL  +  +   S    S   DQ   I   I SKY   +RP E    T VT+ MKILAI S+ V  M+Y  D  LRQ W D RL+W+++  F +Y   +VSP LK+ LWLPDLFFRNGK+GY+H MTLPNYL+R+SPNG +LYSQKITMRFSCQM L+TFPMDTQ C+M+IGSYGYTL EL+F WR +  + ++  +Q+SEF +P +F   DC++ SSTSTGQYSCL A F LQRQLGSY+ +T++P++LI+MVSWL+FW++VDS PARV LGL++LLG+LTQAI +SSTLPRVSYIKAID+W+++ IIFVI  L+EYAVA +V+ RN+      +V+ IV  EL  WC    + Q+S +Q    L R +L FC ++E LL  + ID +K+  K+R P     S VD YSRF+FPA ++ YNCFYW+Y+LVLV 
Sbjct:  111 VPLLTKVSPEGDHSTAHNSSIRDQ---IVEMIMSKYKSYERPPEGGNATVVTMNMKILAIFSIDVRTMDYYVDALLRQTWKDRRLSWSDVPAFANYTQELVSPKLKEQLWLPDLFFRNGKDGYLHTMTLPNYLLRVSPNGEVLYSQKITMRFSCQMHLQTFPMDTQRCDMNIGSYGYTLSELKFVWRADKPVELSDNLQLSEFETPEEFEVADCSENSSTSTGQYSCLLATFELQRQLGSYLATTYIPNVLIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDVWMMFSIIFVIGVLVEYAVALTVLRRNHQETWHQDVRHIVHEELTRWCAVCQQQQLSKIQNAQGLSRGQLGFCEEMELLLTSQLIDDNKEKSKLRRPPGLVESEVDRYSRFMFPASYILYNCFYWMYYLVLVG 542          

Query:  195 EKADQRSLIRAEI----FSKYLKEDRPKE-EEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPEN---SIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            +K++ +S +R +I     +KY   +RP      T V V+MKILAI S+ V  M+Y  D+ LRQ W D RL+WN +  F++Y   +VSP LK+ LWLPDLFFRNGK+GY+HK+TLPNYL+R+SPNG +LYSQKITMRFSCQM L+TFPMDTQ C ++IGSYGYT+ EL+F WR  D + +A  +Q+SEF +P  F T DC+   STSTG Y+CL+A F LQRQLGSY+ +T+VP+ILI+MVSWL+FW++VDS PARV LGL++LLG+LTQAI +SSTLPRVSYIKAID+W+I+ IIFVI  L+EYAVA +V+ +  +     +VK+IV  EL  WC    + Q++ +Q    L R +L+FC ++E LL  + ID  K+  K R P     S +D YSRFLFPA ++ YNCFYW Y+L L
Sbjct:    9 QKSNAKSAMRDQIVNMIMNKYRSYERPPTGANATHVIVFMKILAIFSIDVRTMDYYVDMLLRQTWKDRRLSWNEVPAFQNYTETLVSPKLKEQLWLPDLFFRNGKDGYLHKLTLPNYLLRVSPNGEVLYSQKITMRFSCQMHLQTFPMDTQKCMINIGSYGYTITELKFVWRAEDPVELADALQLSEFETPESFGTEDCSGNYSTSTGAYACLQAWFHLQRQLGSYLATTYVPNILIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDVWMIFSIIFVIGVLVEYAVALTVLRKKQAETWHEDVKMIVHEELTRWCAVCQQQQLAQLQNSQGLSRGQLEFCEEMELLLTSQLIDDSKEKTKPRRPPGLVESEIDNYSRFLFPACYILYNCFYWAYYLGL 426          

Query:  183 GSGSEKADQRSLIRAEIFSKYLKEDRPKEEEQT--EVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHK---KVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
             S    +  R  I   IF  YLK +RP E + T  EV V M++LAI S+ V  M+Y  D YLRQ W D RLAW ++D+F+ Y   IVS  LK  +WLPDLFFRNGKEGY+H MT+PNYL+R+ P+G +LYSQKITMRFSCQM+L+ FPMD Q+C ++IGSYGYTL+EL+F W   + ++++  M+ISEFN+P  F T DCT  S TSTG Y+CL A F L+RQL SY+ +T++P+ILI+MVSWL+FW++VD+ PARV LGL++LLG+LTQA  +S++LPRVSYIKAIDIW+I+ IIFVI  L+EYA+A +++ R  ++    +V+ IV++EL  WCTA  +  +  +Q  + L R +L+FC +LE LL  + ID  K   K +K      S +D YSRFLFPA FL YNCFYW+Y+LVL
Sbjct:   24 SSSPGNSSTRDRIVNHIFRNYLKHERPTELDNTPTEVGVNMRVLAIFSIDVRNMDYYIDAYLRQIWFDKRLAWAHIDEFRQYKQPIVSSKLKNDIWLPDLFFRNGKEGYLHTMTVPNYLLRVMPDGNVLYSQKITMRFSCQMELQNFPMDMQVCGLNIGSYGYTLNELKFVWH-EEKVNLSGRMRISEFNTPETFDTFDCTNSSKTSTGNYTCLNATFKLKRQLSSYLATTYIPNILIIMVSWLSFWVNVDAAPARVPLGLLSLLGILTQASSVSNSLPRVSYIKAIDIWMIFSIIFVIGVLVEYALALTMLRRKRADTWHRDVREIVRQELAKWCTACQQQHLVQLQNSHQLTRGQLEFCEELEALLTNQVIDHQKEKNKAVKPTTTTESEIDSYSRFLFPACFLLYNCFYWLYYLVL 441          

Query:  198 KADQRSLIRAEIFSKYLKEDRPKEE-EQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPEN---SIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 1430
            K+  R  I + I SKY   +RP +    T VTV MK+LAI S+ V  M+Y+ D+ LRQ W D RL+W+ + +F+ +   +VSP LK+ LWLPDLFFRNGK+GY+HK+TLPNYL+R+ PNG +LYSQKITMRFSCQM L+TFPMD+Q C +DIGSYGYTL+EL+F W     + +   +Q+SEF +P KF   DC+   STSTGQY+CLKA F LQRQLGSY+ +T+VP++LI+MVSWL+FW++VDS PARV LGL++LLG+LTQAI +SSTLPRVSYIKAIDIW+I+ IIFVI  L+EYAVA +++ R  S     +VK IV+ EL  WC    + Q+  +Q    L R +++F  +LE+LL  + I+  K   K R P     S VD YSRFLFPA F+ YNCFYW YFLV+VN
Sbjct:  137 KSSMRDRIVSLIMSKYRSYERPPDGGNATIVTVNMKVLAIFSIDVRTMDYNVDLLLRQAWRDRRLSWHEIPEFRDFKEPLVSPKLKEQLWLPDLFFRNGKDGYLHKLTLPNYLLRVHPNGNVLYSQKITMRFSCQMHLQTFPMDSQSCYIDIGSYGYTLNELKFVWNGEKPVELGENLQLSEFETPEKFDAHDCSSGYSTSTGQYACLKATFELQRQLGSYLATTYVPNVLIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDIWMIFSIIFVIGVLVEYAVALTLLRRKQSETWHEDVKDIVREELARWCAICQQQQLVQLQNSQGLTRGQMEFREELEHLLTNQLIEESKDKSKPRRPPGLVESEVDTYSRFLFPACFVLYNCFYWCYFLVIVN 551          

Query:  237 SKYLKEDRPKEE-EQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHK-KVIKVRPPE--NSIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 1430
            SKY   +RP +    T VTV MK+LAI S+ V  M+Y  D+ LRQ W D RL+W ++ +F  +N  +VSP LK+ LWLPDLFFRNGK+GY+HK+TLPNYL+R+ PNG +LYSQKITMRFSCQM L+TFPMD Q C ++IGSYGYTL+EL+F W  N  + +A  +Q+SEF +P +F T DC+   STSTGQY+CL A F LQRQLGSY+ +T++P++LI+MVSWL+FW++VDS PARV LGL++LLG+LTQAI +SSTLPRVSYIKAIDIW+I+ IIFVI  L+EYA+A +++ R  S     +VK IV+ EL  WC    + Q+  +Q  N L + +L+F  +LE+LL  + ID +K K    RPP    S +D YSRFLFPA F+ YNCFYW YFL++VN
Sbjct:    2 SKYRSYERPPDGGNATIVTVNMKVLAIFSIDVRTMDYYIDLLLRQVWRDRRLSWYDIPEFSKFNEPLVSPKLKEQLWLPDLFFRNGKDGYLHKLTLPNYLLRVHPNGNVLYSQKITMRFSCQMHLQTFPMDNQHCHINIGSYGYTLNELKFVWNHNKPVELAEKLQLSEFETPKQFITNDCSSGYSTSTGQYTCLNATFELQRQLGSYLATTYIPNVLIIMVSWLSFWVNVDSAPARVPLGLLSLLGILTQAISVSSTLPRVSYIKAIDIWMIFSIIFVIGVLVEYAIALTILRRKQSETWHEDVKEIVREELARWCAICQQQQLIQLQNSNQLIKGQLEFREELEHLLTNQFIDDYKDKTKPKRPPGLIESEIDTYSRFLFPACFVLYNCFYWCYFLIIVN 403          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEV---KLIVQRELMNWCTAF----DRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K  + H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+ N  + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +       K   + E+   C +F     +        +N+    + Q         + +A  S +++ K+       +D  SR  FP  FLF+N FYWV + +L
Sbjct:   54 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FVSRQHKELLRFRRRRKKSTKEEEVRESCLSFTANAGKDGTMTKPTNNAASTPKGQ-----PTPTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 445          

Query:  264 KEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSL--DRDRLQFCHDLEN-----LLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            K+     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +   +  + +   +R L        R   +   +  +    +D +    +  N     +  EK ++  +K+   R      +D  SR  FP +FL +N FYW+ + ++
Sbjct:   72 KKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQHKELLRFQRR---RRHLKEDEAGEGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSSIPPEKTVEEMRKLFISRAKR---IDTVSRVAFPLVFLIFNIFYWIIYKII 452          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSL--DRDRLQFCHDLEN-----LLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +   +  + +   +R L        R   +   +  +    +D +    +  N     +  EK ++  +K+   R      +D  SR  FP +FL +N FYW+ + ++
Sbjct:   49 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQHKELLRFQRR---RRHLKEDEAGEGRFSFAAYGMGPACLQAKDGMAIKGNNNNAPTSSIPPEKTVEEMRKLFISRAKR---IDTVSRVAFPLVFLIFNIFYWIIYKII 439          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARN----------------YSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDR------LQFCHDL--------------------ENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K  + H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+ N  + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  ++                +  + E E+   +Q   +N   + D +  S  Q+  S DR+       L F  +                         + +A  S +++ K+       +D  SR  FP  FLF+N FYWV + +L
Sbjct:   54 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRRRKKSTKLHDRSFEEELSESLQS--VNGLRSADPVYGSMDQMSESNDREEEVRESCLSFTANAGKDGTMTKPTNNAASTPKGQPTPTVPQAGKSTEEMRKIFIDRAKKIDTVSRAGFPLAFLFFNIFYWVLYKIL 484          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSV 1109
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K  + H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+ N  + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V
Sbjct:   54 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQANGPVQVADGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 339          

Query:   99 INLQYNMFFVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKED-------RPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNN-------LDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNM------ENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFC---HDLENLLIEKAIDSHKKVIKVRPPENSI-----------------VDVYSRFLFPALFLFYNCFYWVYFLVLV 1427
            + L YN F+    I +LAS+  + S  +   ++     +L  +E+  K L          RP        V+  + I +  S+     +Y   VYLRQ W D RLA+++       LD+     +NI      K +W PDLFF N K  + H++T  N ++R++ NG++ Y+ ++T+  SC MDL  FPMDTQ+C M + S+GYT  ++ F+W     +S+  G+ + +F    K +T  CTK  + STG ++C+ A+F L R++G Y++  +VPSILIV++SW++FWI++++ PARV LG+ T+L + TQ+ G  ++LP+VSYIKA+DIW+  C++FV  ALLEYA  N V +R     M      +  + L+V ++ M W           +   N  D D L F      L  LL     DS K VI    P  S+                 +D  SR  FP  FL +N  YW  F V++
Sbjct:    7 VRLLYNFFY----INVLASL--RVSDRMTDRADSTTGPNLSPSEVLDKLLGPSSGYNHRVRPNFGGPAVNVSCGVFIRSFGSIQEATSDYRMTVYLRQRWTDPRLAYSHYPVPLLHLDQ-----SNI------KHIWKPDLFFDNEKSAHFHEITTDNKMLRIANNGVVDYAMRLTLTLSCPMDLHNFPMDTQMCSMYLESFGYTTADIVFHWNGPTPVSLFEGLTLPQFVLSNKISTGSCTK--TYSTGSFTCIFAKFTLHREMGFYLIQLYVPSILIVILSWVSFWINMEAAPARVALGITTVLTLTTQSTGARASLPKVSYIKAMDIWMATCLLFVFAALLEYAAVN-VTSRQSQGFMKKGRGNQKPIDLLVHKK-MFW---------KFLVAEN--DNDLLYFTITIFTLNGLL--PVSDSKKPVIVCIKPLLSLQETKEKMRKKYVACAQTIDNISRLFFPISFLIFNVVYWFAFKVML 456          

Query:  285 VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQ----RELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSI----------VDVYSRFLFPALFLFYNCFYWVYFLV 1421
            VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+  +G +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+   ++ +A G+ + +F    +     CTK    +TG+++C++ +F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  V+R +   +    +          L+  C  F     S + + N   R         ++ +  K +++        P +++I          +D  SR  FP  FL +N FYW+ + V
Sbjct:    8 VTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKDGNVLYSIRLTLTLSCPMDLKNFPMDVQTCAMQLESFGYTMNDLIFEWKQEGAVQVAEGLTLPQFVLKDEKDLVYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVN-FVSRQHKELLRIRRRRQRNQIDLTSLILICNIFTYFINSSVPIFNMFKRVEGNERALTKDSVSVKGVNATNAAPAPAPTQDAIKKKFVDRAKRIDTISRAAFPLAFLIFNIFYWIIYKV 393          

Query:  288 TVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDK--FKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVS 1022
            +VY+K  +  S+  T M+Y   ++LRQ+W+D RL +++  +       +NI      + +W PDLFF N K  Y H++T  N ++R+  NGL+L++ ++T+  SC MDL+ FPMDTQ+C M + S+GYT+ +L F+W   + + I+  + + +F    K  T  C KL S+ TG +SC+ A FVL R++G Y++  +VPS LIV++SW++FWI++++ PARV LG+ T+L M TQ+ G  ++LP+V+
Sbjct:   35 SVYIK--SFGSIEETTMDYQVTIFLRQKWIDPRLTYSHYPEPYLDLDQSNI------QYIWRPDLFFDNEKSAYFHEVTTDNKMLRIFKNGLVLFTVRLTLTLSCPMDLRNFPMDTQMCYMFLESFGYTMADLSFHWDEEEPVIISKELVLPQFVLSSKIDTDSCDKLYSSGTGHFSCISARFVLHREMGFYLIQLYVPSALIVIISWVSFWINMEAAPARVALGITTVLTMTTQSTGARASLPKVT 273          

Query:  162 FQCSQSLGSGSEKADQ-RSLIRAEIFSKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNW-RVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPAR----XXXXXXXXXXXXXQAIGISSTLPRVS-YXXXXXXXXXXXXXXXXXXLLEYAVAN-SVVARNYSNNME---NEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDR-DRLQFCHDLE---NLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            +Q SQ    G     + ++L+R   ++KYL   RP  +     + + + I +I+++S   M+Y+  ++LRQ W D RL +   +K  S +  +V     ++LW+PD F  + K  ++H +T+ N L+R+ PNG +LY+ +IT   +C MDL  +PMD Q C + + S+GY  ++L F W R NDS+     ++++++   G +T+      +   TGQY  L   F L+R +  +I+ T++PS+L+V++SW++FWI   SVPAR       G+ T+L M T  +G  ++LP  + +IKAID+++  C  F+  AL+EYAVA+   + + + ++++   +  +L V +  +N       L  S+     ++D    +++    E   N + +K +        V+ P +  +D+YSR  FP  F+  N  YW+Y+L L
Sbjct:   21 YQGSQEYKEGDALPQKIQNLMRG--YNKYL---RPSFDNGPVAIGMSLDIASIDTISEINMDYTATIFLRQRWQDERLCFEG-NKSLSLDGRLV-----ELLWVPDTFIVDSKRSFLHDITVENRLIRIFPNGTVLYALRITTTVACNMDLTKYPMDKQTCTLQLESWGYNTNDLVFYWTRGNDSVRGLDTLKLAQYTVEGYYTS---VSEAVYETGQYPKLVFHFKLRRNILYFILETYIPSVLLVVLSWVSFWISQSSVPARICIGTNAGVTTVLTMTTLMMGARTSLPNANCFIKAIDVYLGICFSFIFGALVEYAVAHFHTLEQGHIHDIQRPHDPPRLCVFKS-VNRSAGGQSLPFSYDSKTLAVDYISYIEYSASDENKFNYIFKKRLVCIMNCCTVQNPHH--IDIYSRKAFPLTFIVINLCYWIYYLWL 440          

Query:  279 TEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWR--VNDSISIAT-GMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISH 1214
            TEV   + + +   VS  +M+Y+ DV+ RQ WVD RL ++   +    N  +V+      +W PD +FRNGK+   H MT PN L R+  NG +LY+ ++T+   C M L  FPMD   C +  GSY Y   E+ ++W    N+S+ +      + +++  G   + +  K   +  G Y  +   F L+R++G +IV T++P I+ V++S ++FWI+ +SVPAR + G+ T+L M TQ+I    +LP+VSY  A+D ++     FV  AL+E+A      A NY  N + E       +L+    A+ +LQ  H
Sbjct:   69 TEVKTDIYVTSFGPVSDVEMDYTMDVFFRQTWVDERLKFDGPIEILRLNNLMVN-----RIWTPDTYFRNGKKSIAHNMTAPNKLFRIMQNGTVLYTMRLTINAECPMRLMDFPMDGHTCPLKFGSYAYPKSEIIYSWTKGANNSVEVPQESSSLLQYDLTGHNVSSEELK---SKIGDYVVMTVSFYLKRKMGYFIVQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTQSISARGSLPKVSYATAMDWFIAVSFAFVFSALIEFA------AVNYFTNQQAERAKKKAAKLV----AYQKLQHKH 365          

Query:  285 VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIA-TGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEY 1091
            V V  K+++I  +   +M YS D++ RQ W D R A N    F       ++    ++ W PD +F N K    H++T  N  + ++P+G I +S +IT+   C MDL+ +PMD Q C + I SY +T  ++ + W+  D   +     ++++F   G  T    TK  + S G ++ L+AEF  +R++  +I +T++P++++V++SW  FWIH ++VPARV L + T+L  +      + ++P+VSY KAID +++  + F+  +LLEY
Sbjct:    6 VQVEFKVVSIGEIKEAEMVYSMDIFFRQWWYDPRFAHNFSKPFT------MAADATQLFWTPDTYFWNVKNAKYHRVTRENMRVMINPDGKIYFSTRITITAQCDMDLRLYPMDIQYCPLIIESYAHTRSDVDYTWKGGDDQGVEIVSKEMAQFEFIGANT---YTKAQTNSKGSFASLRAEFTFKRRVAYFITATYMPAMILVILSWCTFWIHRNAVPARVTLSITTILTTILLTSSTNGSMPKVSYSKAIDYFLMTSLGFIFMSLLEY 266          

Query:  117 MFFVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEE-EQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIA-TGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAV 1097
            +F  CL +    +   + +  +    E+A   SL    +  ++ +  RP    E+  V +  K+++   +    MEYS D++ RQ W DSR A N    F       ++    ++ W PD +F N K    H++T  N  + ++P+G I +S +IT+   C+MDL  +P+DTQ C + I SY +T+ ++ + W+  ++  +     ++++F+  G    R  TK S+ S G ++ LKA F  +R++  Y+ S +VP +++V++SW  F+I   +VPAR  L + T+L  +  +  ++S +P+VSY+K+ID +++    F+  AL+EY +
Sbjct:   10 LFLGCLSLLFCCAEEKEITDEMRKSMEEARNLSLFINNVIRRHPRNVRPNAGGEKVMVDIEFKVISFGEIKEANMEYSLDIFFRQWWYDSRFAHNYSMPFT------MAADPTELFWTPDTYFWNVKSANYHRVTRENMRVMINPDGKIYFSARITLTCQCEMDLHLYPLDTQECPLRIESYAHTVADVDYRWKGGETQGVEIVSEEMAQFDLLG---VRTDTKKSTNSKGAFASLKATFRFRRRMDFYLSSIYVPEVILVVLSWTTFFITPSAVPARTALSITTILTTILLSSSVNSGMPKVSYMKSIDHFMLISFGFIFAALIEYII 329          

Query:  342 YSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKV--LWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWR----VNDSISIATGMQISEFNSPGKFTTRDCTKLSST-STGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVAN 1103
            ++ D+YLRQ W D RL ++ +      N ++++ + + +  +W+P  +F N K+ Y H +T  NYL+ + PNG + YS ++T+  +C++ L+ FP D Q+CEM + SYGY   ++ + W       D + I+  +++ +F    K T     + ++  + G +S L A+F   R+LG Y++ T++PS+L V +SW +FWI  DS PARV LG+ T+L M+T +    + LP+VSY KAID +++ C+++V  AL+EYA+ N
Sbjct:    2 FTIDMYLRQYWRDPRLIFDPV----PVNTDVLTLNRQTIDEIWIPSTYFFNAKKAYFHDVTTENYLLMIKPNGDVFYSVRLTITMACKLTLQMFPHDVQVCEMMLESYGYQATDVYYRWNSRNSTGDVVYISEDLEMPQF----KITNVKLEERTNIYNIGPHSALIAKFTFHRRLGYYMIQTYIPSMLTVTISWFSFWISPDSPPARVGLGITTVLTMITISNSARAPLPKVSYTKAIDWFLLMCLVYVFGALMEYAIVN 254          

Query:  285 VTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGIS-STLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVAN 1103
            VT  + +++I+      ME++ ++Y RQ W D RLA+       +     +   L   LW PD +F N  +G +H++T+ N  MR+  +G ++ S ++T+  SC MD + FPMD Q C +   SYGYT  ++ + W  ++ ++ A   +I++F    K  T + T+     TG +S L     L R+LG Y+   +VP++LIVM+SWL+F++   S PARV LG+ T+L M T  IGI   +LP VSY+KA+D ++      V  A  EYAV N
Sbjct:    4 VTTELNLVSISQFREADMEFTAEMYFRQAWHDPRLAFGVTMGNSTVPVITLYGDLSDSLWQPDTYFENEVQGKIHELTIKNKYMRVYSDGRVMTSLRVTLSCSCAMDFRKFPMDKQNCGISFASYGYTTADIVYQW-ADERVTWAHDQEIAQFVLE-KIETENLTR--RYITGDFSALGIRLRLNRRLGHYLTRVYVPAVLIVMLSWLSFYLDRHSAPARVSLGITTVLTMTTLLIGIGQGSLPVVSYVKALDWYLFVSYCMVFGAFAEYAVIN 273          

Query:  333 QMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNW--RVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYA-VANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSL-DRDRLQFCHDLENLLIEKAIDSHK---------KVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFL 1418
              +YS D++ RQ W D RLA ++++K  +  AN   P   +  W PD +F N K    H +T  N   ++ P+GLI YS +IT+  SC+MDL+ FPMDTQ C + I SY YT++++ +NW  R    I I  G ++++F+      T       S  TG +  L+  F  +R+   +IV  +VPS  IV +SWL FWI+ ++VPAR+ L +  +L  +     I+S+LPR+SY+KA+D ++I   +F++ +++EY  V N    +  + + ++ ++    RE  N      R     + V N   D D +     L+ L   K  + H+            +    ++  +D  S+ +FP L+  +N  YW Y+L
Sbjct:    2 HQDYSLDIFFRQWWRDERLA-HDVNKVFNMAAN---PG--QYFWTPDTYFVNVKSSKFHHVTRENMRTKIWPDGLIYYSSRITLTASCEMDLRFFPMDTQDCVLKIESYAYTVEDVIYNWNNRGTTPIEIFAG-EMAQFDMTE--MTMQTMITFSLLTGSFDSLRVSFRFKRRTSYFIVQHYVPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESINSSLPRISYLKAVDYYLIISFMFILASMVEYVLVLNVTDYKRITLSRKHSLQPCHCRERSNGLPRPRR----ELPVPNGFSDADHVTNILPLQRLASHKQQEKHEYNFGDQLSSSSYEHYAKKSHFIDHCSKKVFPLLYALFNIVYWSYYL 363          

Query:  264 KEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSL--DRDRLQFCHDLENLLI----EKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            K+     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +   +    +    +E     T   R       +  +    +D +    +  N       EK+I+  KK+   R      +D  SR  FP +FL +N FYW+ + ++
Sbjct:   62 KKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQHKELLRFRRRRRHMKEDE---TGDGRFGFPGYGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKR---IDTVSRVAFPLVFLIFNIFYWITYKII 441          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSL--DRDRLQFCHDLENLLI----EKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +   +    +    +E     T   R       +  +    +D +    +  N       EK+I+  KK+   R      +D  SR  FP +FL +N FYW+ + ++
Sbjct:   39 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQHKELLRFRRRRRHMKEDE---TGDGRFGFPGYGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKR---IDTVSRVAFPLVFLIFNIFYWITYKII 428          

Query:  264 KEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSL--DRDRLQFCHDLENLLI----EKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            K+     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++        ++  + PS+   +W PDLFF N K    H++T  N L+R+S NG +LYS +IT+  +C MDLK FPMD Q C M + S+GYT+++L F W    ++ +A G+ + +F    +   R CTK    +TG+++C++A F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N  +AR +   +    +    +E     T   R       +  +    +D +    +  N       EK+I+  KK+   R      +D  SR  FP +FL +N FYW+ + ++
Sbjct:   77 KKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYSEYPD----DSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIRITLILACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTK--HYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVN-FIARQHKELLRFRRRRRHMKEDE---TGDGRFGFPGYGMGPACLQAKDGMAIKGNNNNAPTSAAPEKSIEEMKKLFIGRAKR---IDTVSRVAFPLVFLIFNIFYWITYKII 456          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAW-----NNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVA--------RNYSNNMENEV--KLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVL 1424
            S Y    RP  +     V+  + I +  S++ T M+Y  +++LRQ+W D RLA+     ++LD         + PS+   +W PDLFF N K  + H++T  N L+R+  NG +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W+ N  + +A G+ + +F    +   R CTK    +TG+++C++  F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V          R + +  + EV    +    +M    +  +   S   V+N++        +        ++ +  +K+   R  +   +D  SR  FP  FLF+N FYWV + +L
Sbjct:   47 SGYDARIRPNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYAEYPDDSLD---------LDPSMLDSIWKPDLFFANEKGAHFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFQWQENGPVQVAEGLTLPQFILKDESDLRYCTK--HYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRTSLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRHKSKTKEEVGESKLTSTAVMTSTPSISK--DSKASVNNAVAPAANTTQNAPAAGGGGRSTEEMRKLFIDRAKK---IDTVSRAGFPLAFLFFNIFYWVLYKIL 442          

Query:  237 SKYLKEDRPK-EEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRE--LMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 1430
            S Y    RP  +     VT  + I +  S++ T M+Y  +++LRQ+W D RLA++   K+   + ++  PS+   +W PDLFF N K    H +T  N L+R+  +G +LYS ++T+  SC MDLK FPMD Q C M + S+GYT+++L F W    ++ ++ G+ + +F    +     CTK    +TG+++C++ +F L+RQ+G Y++  ++PS+LIV++SW++FWI++D+ PARV LG+ T+L M TQ+ G  ++LP+VSY+KAIDIW+  C++FV  ALLEYA  N V  +          +   Q+E  + +    +    IS      +    +             K ID+ +K    R      +D  SR  FP  FL +N FYW+ + ++ N
Sbjct:   57 SGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYS---KYPDSSLDL-DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKDGTVLYSIRLTLILSCPMDLKNFPMDVQTCTMQLESFGYTMNDLVFEWLEYGAVQVSEGLTLPQFIMKEEKELGYCTK--HYNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAGVNFVSRQQKEFLRLRRRQRRNQKEEDMRDGRFNYASYNISQCLSTKNSSAVKNTTPAPNPQPPTPKDIDAMRKKFVDRAKR---IDTISRAAFPLAFLIFNVFYWITYKIIRN 448          

Query:  117 MFFVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVNYSN 1439
            MFFVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARVMLGLVTLLGMLTQAIGISSTLPRVSYIKAIDIWVIWCIIFVICALLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVNYSN
Sbjct:    1 MFFVCLEIFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARVMLGLVTLLGMLTQAIGISSTLPRVSYIKAIDIWVIWCIIFVICALLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSHKKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVNYSN 441          

Query:  192 SEKADQRSLIRAEIFSK--YLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEKAIDSH--KKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVNYS 1436
            S  A QR LI   I  K  Y K++RP E  QT V VYMK+LAINSVSVT+MEYSTDVYLRQEW D RL W NL++F+S+N NIVSPSLKK+LWLPDLFFRNGKEGYVHKMTLPNYLMRL PNG ILYSQKITMRFSC+M+L+TFPMD+Q C MDIGSYGYTLDEL+F WR  D I I+TG+QISEFNSP + +T DCT  SSTSTG+Y+CLKA+F+LQRQLGSY+VSTFVPSILIVMVSWLNFWI+VDSVPARV LGLVTLLGMLTQA GISSTLPRVSYIKAID+WVI CI+FVI ALLEY VA+ +  +  SN  E +V+ IV+ EL  WC+A  R Q  H+Q  N+LDR+RL+FC +LE+LLI  A+D+H  KK IK  P E+S +D YSRFLFPA FL YNCFYW+Y+LVLV+Y+
Sbjct:   26 SPMAQQRDLIMERIVDKKRYKKDERPSEIYQTNVLVYMKVLAINSVSVTKMEYSTDVYLRQEWTDPRLTWENLEEFRSFNNNIVSPSLKKILWLPDLFFRNGKEGYVHKMTLPNYLMRLRPNGRILYSQKITMRFSCEMNLQTFPMDSQECLMDIGSYGYTLDELKFTWRKEDPILISTGLQISEFNSPHQVSTIDCTNDSSTSTGKYTCLKAKFLLQRQLGSYLVSTFVPSILIVMVSWLNFWINVDSVPARVTLGLVTLLGMLTQATGISSTLPRVSYIKAIDVWVIACIMFVIGALLEYVVASVLARKKKSNGWEKDVREIVRHELARWCSACQRQQFFHLQEQNTLDRNRLEFCSELESLLINHALDAHKGKKTIKTTPTEDSDIDSYSRFLFPACFLLYNCFYWLYYLVLVHYA 444          

Query:  138 IFLLASIVFQCSQSLGSGSEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQFCHDLENLLIEK--AIDSH--------KKVIKVRPPENSIVDVYSRFLFPALFLFYNCFYWVYFLVLVN 1430
            IFLLA  V        S S     R  I  +I   Y   +RP E  QT V V+MK+LAINSV+V+ MEYSTD+YLRQ WVD+RL W+NL++FK +N+++VSPSLK  LWLPDLFFRNGKEGYVH MT PNYLMRL PNG +LYSQKITMRFSCQMDL+T+PMDTQ CEM+IGSYGYTLD+L+F W   + + +   +QI EFN+P K  T DCT  S+T TG YSCLKA F+L+RQLGSY+VSTF+P+ LIV+VSWLNFW+ V++VPAR+ LGL+TLLG+LTQA GIS  LPRVSYIKAID+W+I CI+FVI ALLE+AVA++V  +      ++EV+ IV++EL  W  A +R +  HMQ    L+R+ L+FC +L+ LL  +  A + H        K+   +   E S +DVYSR+LFP+ F+FYN  YW+Y+L++V+
Sbjct:   12 IFLLAIHV-----GCNSCSVAGITRERIMDKILQNYSLNERPIESNQTRVMVFMKVLAINSVNVSNMEYSTDLYLRQLWVDARLRWDNLNEFKHFNSSLVSPSLKDRLWLPDLFFRNGKEGYVHIMTKPNYLMRLFPNGEVLYSQKITMRFSCQMDLQTYPMDTQSCEMNIGSYGYTLDQLKFYWSQTNPMELGNNVQIPEFNAPTKVETNDCTNSSTTETGFYSCLKALFILRRQLGSYLVSTFIPNTLIVIVSWLNFWVSVEAVPARITLGLLTLLGILTQASGISGNLPRVSYIKAIDVWLIACIVFVIGALLEFAVASTVAQQKKLYQWKSEVRDIVRQELSRWNLAINRQKTHHMQTSQILNRNELEFCEELDILLTAQQYANNYHSQESAHQIKRQKILSEIEESKIDVYSRYLFPSCFIFYNFCYWIYYLIIVS 447          

Query:  189 GSEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCT-AFDRLQ-ISHMQVH----------------NSLDRDRLQFCHDLENLLIEKAIDS------HKKVIKVR---PPE--NSIVDVYSRFLFPALFLFYNCFYWVYFLVLVNYSN 1439
            G+     R  I+  IF  Y   +RP E +QT VTVYMK+LAINSV V +MEYSTDVYLRQEW+D RLAW++++KF+SYN N+VSP  K+ +WLPDLFFRNGK+GYVH MT PNYL+RL PNG +LYSQKITM+FSCQMDL+TFPMDTQ C MDIGSYGYTLD+L+F WR  + + +   MQI EFN P    T DC++LSSTSTG Y+C+KA F LQRQLGSY+ ST++P++LIVMVSWLNFW+ +D+VPAR+ LGL+TLLG+LTQA G+S+ LPRVSYIKAID+W+I CI+FVI AL+E+A+A+ +  ++ S   + +V+ IV +EL  W   A  + Q I+ +Q+H                NS D    +F H LE  L  + +++       K + K +   PP   +S +D YS+FLFPA F+ YNCFYW+Y+L+LV   N
Sbjct:    7 GTSMNSDREQIQNHIFKGYKSNERPSENKQTIVTVYMKVLAINSVDVIKMEYSTDVYLRQEWIDERLAWDHIEKFRSYNNNLVSPLFKEKIWLPDLFFRNGKDGYVHSMTTPNYLLRLQPNGEVLYSQKITMKFSCQMDLQTFPMDTQECNMDIGSYGYTLDQLKFRWRSWEPMILPPVMQIPEFNQPTNVKTIDCSELSSTSTGDYTCIKATFFLQRQLGSYLASTYIPNVLIVMVSWLNFWVSIDAVPARITLGLLTLLGILTQATGMSANLPRVSYIKAIDVWIIACILFVIGALIEFAIASMISRKSKSELWQRDVQNIVHQELFKWSKMALKKQQSINFLQMHLMGTPKTNSFTNLAQMNSTDNSANEFYHKLEVFLTAQLLEASPNEKLRKSISKPQVSEPPVQIDSEIDGYSQFLFPAFFMLYNCFYWLYYLILVRKRN 452          

Query:  192 SEKADQRSLIRAEIFSKYLKEDRPKEEEQTEVTVYMKILAINSVSVTQMEYSTDVYLRQEWVDSRLAWNNLDKFKSYNANIVSPSLKKVLWLPDLFFRNGKEGYVHKMTLPNYLMRLSPNGLILYSQKITMRFSCQMDLKTFPMDTQICEMDIGSYGYTLDELRFNWRVNDSISIATGMQISEFNSPGKFTTRDCTKLSSTSTGQYSCLKAEFVLQRQLGSYIVSTFVPSILIVMVSWLNFWIHVDSVPARXXXXXXXXXXXXXQAIGISSTLPRVSYXXXXXXXXXXXXXXXXXXLLEYAVANSVVARNYSNNMENEVKLIVQRELMNWCTAFDRLQISHMQVHNSLDRDRLQF-----CHDLENLLIEKAIDSHKK--VIKVR--PPENSI---VDVYSRFLFPALFLFYNCFYWVYFLVLVNYS 1436
            SE    R  I   +F  Y   +RP E +QTEV VYM++LAINSV V +MEYSTDV LRQEW+D RL W+   +  SYN +I SP+LK+ +WLPDLFFRNGK+GYVH MTLPNYLMRL+ NG+ILYSQKITMRFSCQM+L TFPMD+Q C MDIGSYGYTLD+L+F WR  + I IA+ +QI EFN      T DC+K + TSTG Y+CLKA F L+RQLGSY+ ST++P++LIVMVSWLNFW+ V+++PAR+ LGL+TLLG+LTQA G+S++LPRVSYIKAIDIW+I CIIFVI AL+E+A+A+ +  R  S + + +V+ IV++EL  WC      Q   +Q+ NS   DR QF       DLE LL    +   KK  V KV    P+ S+   +D YSRFLFPA F+ YNCFYW+Y+LVLV+++
Sbjct:   43 SENNVTREDILKIVFENYNLHERPSEVKQTEVVVYMRVLAINSVDVLKMEYSTDVLLRQEWLDDRLTWHRHPRLASYNKSISSPALKEKVWLPDLFFRNGKKGYVHSMTLPNYLMRLNSNGMILYSQKITMRFSCQMNLSTFPMDSQECIMDIGSYGYTLDQLKFLWREKEPIIIASNIQIPEFNPSTDPYTFDCSKEAGTSTGNYTCLKASFHLRRQLGSYLASTYIPNVLIVMVSWLNFWVSVEAIPARITLGLLTLLGILTQATGMSNSLPRVSYIKAIDIWIIACIIFVIGALIEFAMASMIARRRKSEDWQKQVREIVRQELARWCAVC--QQQQLVQIQNSSLIDRTQFETPIGTEDLEILLCPDTVQKWKKKPVQKVNRSKPQKSVDSEIDCYSRFLFPACFVLYNCFYWLYYLVLVHHN 467