WD40 repeat-containing protein SMU1

Overview


Name	WD40 repeat-containing protein SMU1
Smed ID	SMED30035299
Length (bp)	2139

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of WD40 repeat-containing protein SMU1 (SMED30035299) t-SNE clustered cells

Violin plots show distribution of expression levels for WD40 repeat-containing protein SMU1 (SMED30035299) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of WD40 repeat-containing protein SMU1 (SMED30035299) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for WD40 repeat-containing protein SMU1 (SMED30035299) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035299

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 2

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Specimen	Lifecycle	Evidence
X1 cell	SMED30035299	SMESG000005039.1	SmedASXL_019400	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X2 cell	SMED30035299	SMESG000005039.1	SmedASXL_019400	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015

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Homology

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
Match: SMU1 (SMU1 DNA replication regulator and spliceosomal factor [Source:HGNC Symbol;Acc:HGNC:18247])

HSP 1 Score: 431.795 bits (1109), Expect = 7.314e-144
Identity = 191/303 (63.04%), Postives = 252/303 (83.17%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 513

HSP 2 Score: 286.574 bits (732), Expect = 7.682e-88
Identity = 157/206 (76.21%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L R LATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG +ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLS 206

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
Match: WDR5 (WD repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:12757])

HSP 1 Score: 137.502 bits (345), Expect = 5.627e-35
Identity = 86/305 (28.20%), Postives = 150/305 (49.18%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP+G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED L+Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   42 AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
Match: WDR5B (WD repeat domain 5B [Source:HGNC Symbol;Acc:HGNC:17826])

HSP 1 Score: 132.109 bits (331), Expect = 3.966e-33
Identity = 87/304 (28.62%), Postives = 147/304 (48.36%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLW 2095
            VG +  V   KFSP+G++L + + D  I +W    GK  K L     E        +  + +S DS  L + S D  +K++ +++G+CLK   K H   V    F+     I+SGSFD++V+I  +K+GK LK    H+  V+ V +      I+S S DG  R+W   +G+         LV  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED L+Y +NLQ +  +++ +  H   VI    HP +NLIA+ A   D  ++LW
Sbjct:   38 VGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLE--------ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTL-KGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQ-----CLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQK-LQGHTDVVISAACHPTENLIASAALENDKTIKLW 326

HSP 2 Score: 63.929 bits (154), Expect = 3.231e-10
Identity = 67/249 (26.91%), Postives = 109/249 (43.78%), Query Frame = 2

Query: 1379 SRDSE-MLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTN-TVAIINIQ-GQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGE-------DKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            SRD++  LA  S   + K         LK     H + V+SV+FS +G  + S S D+ + I G   GK  K   GH   ++DV ++ D+  ++SAS D TL+LW +++G     +    L G    +      P +    IIS   + TV I  ++ G+ +++ SA     SD V+ +       F C G        D L   ++  +   L+  +   +  V  +   P+   I T   D  L+LW
Sbjct:    6 SRDAKAQLALSSSANQSKEVPENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKTLKLWDVRSG-----KCLKTLKGHSNYVFCCNFNPPS--NLIISGSFDETVKIWEVKTGKCLKTLSA----HSDPVSAVH------FNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLW 237

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
Match: KATNB1 (katanin regulatory subunit B1 [Source:HGNC Symbol;Acc:HGNC:6217])

HSP 1 Score: 102.449 bits (254), Expect = 7.130e-22
Identity = 62/208 (29.81%), Postives = 108/208 (51.92%), Query Frame = 2

Query: 1148 WALLHKNLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVM 1771
            W++   N  + L    G +S VE  + +   + +V G+  G I VW+    KI + L        M  +  + SL F    E +A+GSQD  IK++ I+   C+ ++ + H + V  ++FS DG  + S + D +V++  + +GK++ EF GHT  VN V + P+   + S SSD T+R W L+      ++  S + G+  P+ +V+
Sbjct:   48 WSINKPNCIMSLT---GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--------MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY-RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK-----FQVVSCIEGEPGPVRSVL 238

HSP 2 Score: 62.003 bits (149), Expect = 2.632e-9
Identity = 43/174 (24.71%), Postives = 87/174 (50.00%), Query Frame = 2

Query: 1178 ILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKD---LKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLW 1690
            IL   +G  +++    F P G+++ +G+ D  I++W+     IR+     +Y+         +AV  L FS D + LA+ + D  +K++ +  G+ + +F   H   V  V+F  +   + SGS D+++R   ++  +++   +G    V  V++ PD   + S   D +LR++
Sbjct:   97 ILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD-----IRRKGCVFRYRGHS------QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVY 257

HSP 3 Score: 53.9138 bits (128), Expect = 8.724e-7
Identity = 55/212 (25.94%), Postives = 94/212 (44.34%), Query Frame = 2

Query: 1475 AHVKGVTSVQFSKDGTNIL-SGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNT---VAIINIQGQIVRSFSAPKRDGSDFVATI-ISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            AH   V+S+   K    +L +G  D  V +  +     +    GHTS V  V      + I++ S  G++R+W L+  +  I R    L+G +A I ++   P    +F+ S   +T   +  I  +G + R      R  S  V  +  SP G+W     +D  +  ++L A  K+    P H   V  +  HP++ L+A+ + D  +R W
Sbjct:   18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAK--ILRT---LMGHKANICSLDFHPYG--EFVASGSQDTNIKLWDIRRKGCVFR-----YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA-GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
Match: RACK1 (receptor for activated C kinase 1 [Source:HGNC Symbol;Acc:HGNC:4399])

HSP 1 Score: 88.1965 bits (217), Expect = 2.402e-19
Identity = 55/174 (31.61%), Postives = 89/174 (51.15%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKF-EKAHVKGVTSVQFSKDGTN--ILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            G S  V     S DGQ+ ++G+ DG + +W+  TG   +         F+   K VLS+ FS D+  + +GS+D  IK++    G C     +++H + V+ V+FS + +N  I+S  +DK V++  + + KL     GHT ++N V  +PD     S   DG   LW L  G+
Sbjct:   20 GHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR--------RFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNT-LGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK 184

HSP 2 Score: 59.6918 bits (143), Expect = 1.570e-9
Identity = 54/176 (30.68%), Postives = 84/176 (47.73%), Query Frame = 2

Query: 1589 KEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHT--VMPVPRNTD--QFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATI-ISPKGE--WFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            +  +GH+ FV+DV+ + D Q  +S S DGTLRLW L TG  T  R + G        HT  V+ V  ++D  Q +  ++  T+ + N  G  V  ++      S++V+ +  SP          G DKL+  +NL A  KL+     H   +  +   P  +L A+  +DG   LW
Sbjct:   16 RALRGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT--RRFVG--------HTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLG--VCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNL-ANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLW 178

HSP 3 Score: 57.3806 bits (137), Expect = 1.102e-8
Identity = 28/74 (37.84%), Postives = 44/74 (59.46%), Query Frame = 2

Query: 1472 KAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWS 1693
            + H   V+ V  S DG   LSGS+D ++R+  + +G   + F GHT  V  V ++ DN+ I+S S D T++LW+
Sbjct:   19 RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWN 92

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Celegans
Match: smu-1 (Smu-1 suppressor of mec-8 and unc-52 protein [Source:UniProtKB/Swiss-Prot;Acc:G5EEG7])

HSP 1 Score: 353.984 bits (907), Expect = 3.729e-114
Identity = 162/299 (54.18%), Postives = 227/299 (75.92%), Query Frame = 2

Query: 1205 SHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEG-TIWRAYSGLVGQEAPIHTVMPVPR-NTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            S+ E A FSPD  YLV+G+ DGFIEVWN++ GK+RKDLKYQAQ+N M+M+ AV  + FSRDSEMLA GS DGKIKV++++TG CL++F++AH KGV +V+FSKD ++ILSG  D  VR+HGMKSGK LKE +GH+S++ DV Y+ +  HIIS S+DG++R+W  K+GE  + +R  S    ++ PI  V+P+P+ +  Q I+ N++NT+ ++NI GQ+VR+ ++ KR+  DF+  I+SPKGEW Y + ED ++YCF +     LE T+P+ ++  IGL HHPHQNLIA+YAEDGLL+LW
Sbjct:  215 SYPESAVFSPDANYLVSGSKDGFIEVWNYMNGKLRKDLKYQAQDNLMMMDAAVRCISFSRDSEMLATGSIDGKIKVWKVETGDCLRRFDRAHTKGVCAVRFSKDNSHILSGGNDHVVRVHGMKSGKCLKEMRGHSSYITDVRYSDEGNHIISCSTDGSIRVWHGKSGECLSTFRVGS----EDYPILNVIPIPKSDPPQMIVCNRSNTLYVVNISGQVVRTMTSGKREKGDFINCILSPKGEWAYAIAEDGVMYCF-MVLSGTLETTLPVTERLPIGLAHHPHQNLIASYAEDGLLKLW 508

HSP 2 Score: 234.187 bits (596), Expect = 1.285e-68
Identity = 132/205 (64.39%), Postives = 167/205 (81.46%), Query Frame = 1

Query:   25 AIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            +IEIES+DV+RLIEQ+LKE+NL RTLA LQEET +SLNTVDS++ F  EIT+G+W+ VL+  Q+LKLP  KLIDLYE V+IEL+ELREL   R + RQTDPMIL+KQ  P+R A LE+L+ R YFD +E Y +  +KEKRR  IA +L+SEV VV PSRLL+LLGQ+LKWQ HQGLLPPG++ID+FRGKAA +EQ +E+ PT ++
Sbjct:    3 SIEIESSDVIRLIEQFLKESNLHRTLAILQEETNVSLNTVDSIDGFCNEITSGNWDNVLKTVQSLKLPAKKLIDLYEHVIIELVELRELATARLVARQTDPMILLKQIDPDRFARLESLINRPYFDGQEVYGD-VSKEKRRSVIAQTLSSEVHVVAPSRLLSLLGQSLKWQLHQGLLPPGTAIDLFRGKAAQKEQIEERYPTMMA 206

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Query: 1205 SHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEG-TIWRAYSGLVGQEAPIHTVMPVPR-NTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            S+ E A FSPD  YLV+G+ DGFIEVWN++ GK+RKDLKYQAQ+N M+M+ AV  + FSRDSEMLA GS DGKIKV++++TG CL++F++AH KGV +V+FSKD ++ILSG  D  VR+HGMKSGK LKE +GH+S++ DV Y+ +  HIIS S+DG++R+W  K+GE  + +R  S    ++ PI  V+P+P+ +  Q I+ N++NT+ ++NI GQ+VR+ ++ KR+  DF+  I+SPKGEW Y + ED ++YCF +     LE T+P+ ++  IGL HHPHQNLIA+YAEDGLL+LW
Sbjct:  215 SYPESAVFSPDANYLVSGSKDGFIEVWNYMNGKLRKDLKYQAQDNLMMMDAAVRCISFSRDSEMLATGSIDGKIKVWKVETGDCLRRFDRAHTKGVCAVRFSKDNSHILSGGNDHVVRVHGMKSGKCLKEMRGHSSYITDVRYSDEGNHIISCSTDGSIRVWHGKSGECLSTFRVGS----EDYPILNVIPIPKSDPPQMIVCNRSNTLYVVNISGQVVRTMTSGKREKGDFINCILSPKGEWAYAIAEDGVMYCF-MVLSGTLETTLPVTERLPIGLAHHPHQNLIASYAEDGLLKLW 508

HSP 2 Score: 234.187 bits (596), Expect = 1.285e-68
Identity = 132/205 (64.39%), Postives = 167/205 (81.46%), Query Frame = 1

Query:   25 AIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            +IEIES+DV+RLIEQ+LKE+NL RTLA LQEET +SLNTVDS++ F  EIT+G+W+ VL+  Q+LKLP  KLIDLYE V+IEL+ELREL   R + RQTDPMIL+KQ  P+R A LE+L+ R YFD +E Y +  +KEKRR  IA +L+SEV VV PSRLL+LLGQ+LKWQ HQGLLPPG++ID+FRGKAA +EQ +E+ PT ++
Sbjct:    3 SIEIESSDVIRLIEQFLKESNLHRTLAILQEETNVSLNTVDSIDGFCNEITSGNWDNVLKTVQSLKLPAKKLIDLYEHVIIELVELRELATARLVARQTDPMILLKQIDPDRFARLESLINRPYFDGQEVYGD-VSKEKRRSVIAQTLSSEVHVVAPSRLLSLLGQSLKWQLHQGLLPPGTAIDLFRGKAAQKEQIEERYPTMMA 206

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Celegans
Match: wdr-5.2 (WD repeat-containing protein wdr-5.2 [Source:UniProtKB/Swiss-Prot;Acc:Q93847])

HSP 1 Score: 129.413 bits (324), Expect = 3.638e-32
Identity = 86/295 (29.15%), Postives = 145/295 (49.15%), Query Frame = 2

Query: 1223 KFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQG-QIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
            KFSPDG+Y+ +G+ D  I++W       R D  Y+  +  M     +    +S DS+++ + S D  +KVF + +G+C+K   K H   V    F+  GT I SGSFD+++RI   ++G  +    GH   V+ V +  D  ++ S S DG +R+W   TG          L+ +E P  T +    N    + SN  NT+ + + Q  ++++ ++  +       A      G+W     ED  +Y +NLQ    L+ T+  H+  V+    HP QN+IA+ A   D  +++W+
Sbjct:  114 KFSPDGRYMGSGSADCSIKIW-------RMDFVYE--KTLMGHRLGINEFSWSSDSKLIVSCSDDKLVKVFDVSSGRCVKTL-KGHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGNTIFSIPGHEDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGT-----CVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQTREILQ-TLDGHNTAVMCTDCHPGQNIIASAALEPDMRIKIWR 392

HSP 2 Score: 77.7962 bits (190), Expect = 5.471e-15
Identity = 47/174 (27.01%), Postives = 85/174 (48.85%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTS---FVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            G +++V    F+P G  + +G+ D  I +W    G     +           E  V S+ F+RD   LA+GS DG ++++   TG C+K         +T V+FS +G  IL+ + + ++++   +  ++LKE+ GH +    V         + I+S S D  + +W+L+T E
Sbjct:  188 GHTNYVFCCCFNPSGTLIASGSFDETIRIWCARNGNTIFSIPGH--------EDPVSSVCFNRDGAYLASGSYDGIVRIWDSTTGTCVKTLIDEEHPPITHVKFSPNGKYILASNLNNTLKLWDYQKLRVLKEYTGHENSKYCVAANFSVTGGKWIVSGSEDHKVYIWNLQTRE 353

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Celegans
Match: wdr-5.1 (WD repeat-containing protein wdr-5.1 [Source:UniProtKB/Swiss-Prot;Acc:Q17963])

HSP 1 Score: 113.62 bits (283), Expect = 6.273e-27
Identity = 90/344 (26.16%), Postives = 153/344 (44.48%), Query Frame = 2

Query: 1097 GLRFQV*SPNINFREEPWALLHKNLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEK-------AVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
            G   Q  +PN        +  +K +C +     G +  +  AKFSP G+YL T + D  +++WN                + MI E+        V  + +S DS  + + S D  +K+F I T + + K  K H   V    F+   + ++SGSFD+SVRI  +K+G  +K    H+  V+ V +  D   I S S DG +R+W    G+         LV  E P    +    N    + SN  +T+ + +  +G+ ++ ++  +       A      G+W     ED  +Y +NLQ   ++ + +  H + V+    HP QN+IA+ A   D  + +W+
Sbjct:   56 GASAQTPNPNAAGASASGSANYKLMCTL----EGHTKSISSAKFSPCGKYLGTSSADKTVKIWNM---------------DHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSR-MTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQ-----CIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTR-EIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKIHIWR 373

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Query: 1097 GLRFQV*SPNINFREEPWALLHKNLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEK-------AVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
            G   Q  +PN        +  +K +C +     G +  +  AKFSP G+YL T + D  +++WN                + MI E+        V  + +S DS  + + S D  +K+F I T + + K  K H   V    F+   + ++SGSFD+SVRI  +K+G  +K    H+  V+ V +  D   I S S DG +R+W    G+         LV  E P    +    N    + SN  +T+ + +  +G+ ++ ++  +       A      G+W     ED  +Y +NLQ   ++ + +  H + V+    HP QN+IA+ A   D  + +W+
Sbjct:   56 GASAQTPNPNAAGASASGSANYKLMCTL----EGHTKSISSAKFSPCGKYLGTSSADKTVKIWNM---------------DHMICERTLTGHKLGVNDIAWSSDSRCVVSASDDKTLKIFEIVTSR-MTKTLKGHNNYVFCCNFNPQSSLVVSGSFDESVRIWDVKTGMCIKTLPAHSDPVSAVSFNRDGSLIASGSYDGLVRIWDTANGQ-----CIKTLVDDENPPVAFVKFSPNGKYILASNLDSTLKLWDFSKGKTLKQYTGHENSKYCIFANFSVTGGKWIISGSEDCKIYIWNLQTR-EIVQCLEGHTQPVLASDCHPVQNIIASGALEPDNKIHIWR 373

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
Match: Smu1 (gene:FBgn0038666 transcript:FBtr0083721)

HSP 1 Score: 431.409 bits (1108), Expect = 4.206e-144
Identity = 190/302 (62.91%), Postives = 254/302 (84.11%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYL+TG++DGF+EVWNF TGK+RKDLKYQAQ+ FM+ME+AVL+L FSRDSEM+A+G+QDG+IKV+RI TGQCL+KFEKAH KG+T +QFS+D + +LS SFD +VR+HG+KSGK+LKEFKGH+SFVN+  + PD   ++SASSDGT+++WSLKT E     A    +G E  ++TV+ +P+N + FI+ N++NTV I+N+QGQIVRSFS+ KR+G  F++  +SP+GE+ YC GED++LYCF++ +  KLERT+ +H+KDVIGL HHPHQNL+A+Y+EDGLL+LWKP
Sbjct:  212 GQKSHVECAQFSPDGQYLITGSVDGFLEVWNFTTGKVRKDLKYQAQDQFMMMEQAVLALNFSRDSEMVASGAQDGQIKVWRIITGQCLRKFEKAHTKGITCLQFSRDNSQVLSASFDYTVRLHGLKSGKMLKEFKGHSSFVNEATFTPDGHSVLSASSDGTVKVWSLKTTECV---ATYKPLGNELAVNTVLILPKNPEHFIVCNRSNTVVIMNMQGQIVRSFSSGKREGGAFISATLSPRGEFIYCAGEDQVLYCFSV-SSGKLERTLNVHEKDVIGLTHHPHQNLLASYSEDGLLKLWKP 509

HSP 2 Score: 277.715 bits (709), Expect = 8.293e-85
Identity = 149/205 (72.68%), Postives = 182/205 (88.78%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQL 636
            M+IEIESADV+RLI+QYLKE+NLM+TL TLQEETG+SLNTVDSV+ F+ +I+NGHW+ VL+VTQ+LKLPD KL++LYEQ+V+ELIELRELG  R+LLRQTDPM ++KQ +PER+ HLE +L R+YFDPREAY EG +KEKRR  IA  L+ EV VVP SRLLALLGQALKWQQHQGLLPPG++ID+FRGKAA+++QE+E  PTQL
Sbjct:    1 MSIEIESADVIRLIQQYLKESNLMKTLQTLQEETGVSLNTVDSVDGFVQDISNGHWDTVLKVTQSLKLPDKKLLNLYEQIVLELIELRELGAARSLLRQTDPMTMLKQQEPERYIHLENMLQRAYFDPREAYAEGSSKEKRRTVIAQELSGEVHVVPSSRLLALLGQALKWQQHQGLLPPGTTIDLFRGKAAMKDQEEEMYPTQL 205

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
Match: Smu1 (gene:FBgn0038666 transcript:FBtr0304690)

HSP 1 Score: 431.409 bits (1108), Expect = 4.206e-144
Identity = 190/302 (62.91%), Postives = 254/302 (84.11%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYL+TG++DGF+EVWNF TGK+RKDLKYQAQ+ FM+ME+AVL+L FSRDSEM+A+G+QDG+IKV+RI TGQCL+KFEKAH KG+T +QFS+D + +LS SFD +VR+HG+KSGK+LKEFKGH+SFVN+  + PD   ++SASSDGT+++WSLKT E     A    +G E  ++TV+ +P+N + FI+ N++NTV I+N+QGQIVRSFS+ KR+G  F++  +SP+GE+ YC GED++LYCF++ +  KLERT+ +H+KDVIGL HHPHQNL+A+Y+EDGLL+LWKP
Sbjct:  212 GQKSHVECAQFSPDGQYLITGSVDGFLEVWNFTTGKVRKDLKYQAQDQFMMMEQAVLALNFSRDSEMVASGAQDGQIKVWRIITGQCLRKFEKAHTKGITCLQFSRDNSQVLSASFDYTVRLHGLKSGKMLKEFKGHSSFVNEATFTPDGHSVLSASSDGTVKVWSLKTTECV---ATYKPLGNELAVNTVLILPKNPEHFIVCNRSNTVVIMNMQGQIVRSFSSGKREGGAFISATLSPRGEFIYCAGEDQVLYCFSV-SSGKLERTLNVHEKDVIGLTHHPHQNLLASYSEDGLLKLWKP 509

HSP 2 Score: 277.715 bits (709), Expect = 8.293e-85
Identity = 149/205 (72.68%), Postives = 182/205 (88.78%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQL 636
            M+IEIESADV+RLI+QYLKE+NLM+TL TLQEETG+SLNTVDSV+ F+ +I+NGHW+ VL+VTQ+LKLPD KL++LYEQ+V+ELIELRELG  R+LLRQTDPM ++KQ +PER+ HLE +L R+YFDPREAY EG +KEKRR  IA  L+ EV VVP SRLLALLGQALKWQQHQGLLPPG++ID+FRGKAA+++QE+E  PTQL
Sbjct:    1 MSIEIESADVIRLIQQYLKESNLMKTLQTLQEETGVSLNTVDSVDGFVQDISNGHWDTVLKVTQSLKLPDKKLLNLYEQIVLELIELRELGAARSLLRQTDPMTMLKQQEPERYIHLENMLQRAYFDPREAYAEGSSKEKRRTVIAQELSGEVHVVPSSRLLALLGQALKWQQHQGLLPPGTTIDLFRGKAAMKDQEEEMYPTQL 205

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
Match: Smu1 (gene:FBgn0038666 transcript:FBtr0304689)

HSP 1 Score: 431.409 bits (1108), Expect = 4.206e-144
Identity = 190/302 (62.91%), Postives = 254/302 (84.11%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYL+TG++DGF+EVWNF TGK+RKDLKYQAQ+ FM+ME+AVL+L FSRDSEM+A+G+QDG+IKV+RI TGQCL+KFEKAH KG+T +QFS+D + +LS SFD +VR+HG+KSGK+LKEFKGH+SFVN+  + PD   ++SASSDGT+++WSLKT E     A    +G E  ++TV+ +P+N + FI+ N++NTV I+N+QGQIVRSFS+ KR+G  F++  +SP+GE+ YC GED++LYCF++ +  KLERT+ +H+KDVIGL HHPHQNL+A+Y+EDGLL+LWKP
Sbjct:  212 GQKSHVECAQFSPDGQYLITGSVDGFLEVWNFTTGKVRKDLKYQAQDQFMMMEQAVLALNFSRDSEMVASGAQDGQIKVWRIITGQCLRKFEKAHTKGITCLQFSRDNSQVLSASFDYTVRLHGLKSGKMLKEFKGHSSFVNEATFTPDGHSVLSASSDGTVKVWSLKTTECV---ATYKPLGNELAVNTVLILPKNPEHFIVCNRSNTVVIMNMQGQIVRSFSSGKREGGAFISATLSPRGEFIYCAGEDQVLYCFSV-SSGKLERTLNVHEKDVIGLTHHPHQNLLASYSEDGLLKLWKP 509

HSP 2 Score: 277.715 bits (709), Expect = 8.293e-85
Identity = 149/205 (72.68%), Postives = 182/205 (88.78%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQL 636
            M+IEIESADV+RLI+QYLKE+NLM+TL TLQEETG+SLNTVDSV+ F+ +I+NGHW+ VL+VTQ+LKLPD KL++LYEQ+V+ELIELRELG  R+LLRQTDPM ++KQ +PER+ HLE +L R+YFDPREAY EG +KEKRR  IA  L+ EV VVP SRLLALLGQALKWQQHQGLLPPG++ID+FRGKAA+++QE+E  PTQL
Sbjct:    1 MSIEIESADVIRLIQQYLKESNLMKTLQTLQEETGVSLNTVDSVDGFVQDISNGHWDTVLKVTQSLKLPDKKLLNLYEQIVLELIELRELGAARSLLRQTDPMTMLKQQEPERYIHLENMLQRAYFDPREAYAEGSSKEKRRTVIAQELSGEVHVVPSSRLLALLGQALKWQQHQGLLPPGTTIDLFRGKAAMKDQEEEMYPTQL 205

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
Match: wds (gene:FBgn0040066 transcript:FBtr0308566)

HSP 1 Score: 135.576 bits (340), Expect = 1.873e-34
Identity = 85/305 (27.87%), Postives = 151/305 (49.51%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP+G++L + + D  I++W    GK  K +           +  +  + +S DS +L +GS D  +KV+ + TG+ LK   K H   V    F+     I+SGSFD+SVRI  +++GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ++  +++ +  H   V+    HP +N+IA+ A   D  ++LWK
Sbjct:   69 AGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQK-LQGHTDTVLCTACHPTENIIASAALENDKTIKLWK 358

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
Match: wds (gene:FBgn0040066 transcript:FBtr0070438)

HSP 1 Score: 135.576 bits (340), Expect = 1.873e-34
Identity = 85/305 (27.87%), Postives = 151/305 (49.51%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP+G++L + + D  I++W    GK  K +           +  +  + +S DS +L +GS D  +KV+ + TG+ LK   K H   V    F+     I+SGSFD+SVRI  +++GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ++  +++ +  H   V+    HP +N+IA+ A   D  ++LWK
Sbjct:   69 AGHTKAVSAVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSRLLVSGSDDKTLKVWELSTGKSLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVRTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQSKEVVQK-LQGHTDTVLCTACHPTENIIASAALENDKTIKLWK 358

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
Match: smu1a (SMU1 DNA replication regulator and spliceosomal factor a [Source:NCBI gene;Acc:393168])

HSP 1 Score: 432.565 bits (1111), Expect = 2.333e-144
Identity = 192/303 (63.37%), Postives = 249/303 (82.18%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL+++E+AH KGVT + FSKD T ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+    PD  H ISASSDGT+++W++KT E T  +++     G +  ++ V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMSFSRDTEMLATGAQDGKIKVWKIQSGQCLRRYERAHSKGVTCLSFSKDSTQILSASFDQTIRIHGLKSGKCLKEFRGHSSFVNEATLTPDGHHAISASSDGTVKVWNMKTTECTSTFKSLGTSAGTDITVNNVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

HSP 2 Score: 283.493 bits (724), Expect = 6.035e-87
Identity = 155/206 (75.24%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIESADV+RLI QYLKEN+L RTLA LQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQ+LKWQQHQGLLPPG +ID+FRGKAAV++ E+E+ PTQL+
Sbjct:    1 MSIEIESADVIRLIMQYLKENSLHRTLAMLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLA 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
Match: smu1b (SMU1 DNA replication regulator and spliceosomal factor b [Source:ZFIN;Acc:ZDB-GENE-130530-635])

HSP 1 Score: 400.979 bits (1029), Expect = 1.185e-134
Identity = 181/303 (59.74%), Postives = 241/303 (79.54%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            G  SHVE A+FSPDGQYL+TG++DGFIEVWNF TGKI KDLKYQAQ+NFM+M++AVL L  S DS ++A+G+QDGKI+V+RI  G CL + E+AH K VTSV F++D T +LS SFD+++RIHG+KSGK LKEF+GHT+ VNDVIY+ D QH+ISAS+DGT+++W++KT + T   +      G +  ++ V+ VP+  + F++SN+TNTV + NI GQ++RSF +  R+G+DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:   31 GPKSHVECARFSPDGQYLITGSVDGFIEVWNFTTGKICKDLKYQAQDNFMMMDEAVLCLAVSHDSHVIASGAQDGKIQVWRILNGTCLNRLERAHSKAVTSVCFNRDSTQLLSSSFDQTIRIHGLKSGKCLKEFRGHTAHVNDVIYSHDGQHVISASADGTVKVWTVKTMDCTHTIKTPDIPEGTDITVNNVVLVPKTPEHFVVSNRTNTVVVTNIHGQVMRSFCSGVREGADFVCCTLSPRGEWIYCVGEDYVLYCFS-TITGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 332

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
Match: smu1b (SMU1 DNA replication regulator and spliceosomal factor b [Source:ZFIN;Acc:ZDB-GENE-130530-635])

HSP 1 Score: 399.823 bits (1026), Expect = 4.842e-134
Identity = 181/303 (59.74%), Postives = 241/303 (79.54%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            G  SHVE A+FSPDGQYL+TG++DGFIEVWNF TGKI KDLKYQAQ+NFM+M++AVL L  S DS ++A+G+QDGKI+V+RI  G CL + E+AH K VTSV F++D T +LS SFD+++RIHG+KSGK LKEF+GHT+ VNDVIY+ D QH+ISAS+DGT+++W++KT + T   +      G +  ++ V+ VP+  + F++SN+TNTV + NI GQ++RSF +  R+G+DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:   47 GPKSHVECARFSPDGQYLITGSVDGFIEVWNFTTGKICKDLKYQAQDNFMMMDEAVLCLAVSHDSHVIASGAQDGKIQVWRILNGTCLNRLERAHSKAVTSVCFNRDSTQLLSSSFDQTIRIHGLKSGKCLKEFRGHTAHVNDVIYSHDGQHVISASADGTVKVWTVKTMDCTHTIKTPDIPEGTDITVNNVVLVPKTPEHFVVSNRTNTVVVTNIHGQVMRSFCSGVREGADFVCCTLSPRGEWIYCVGEDYVLYCFS-TITGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 348

HSP 2 Score: 63.929 bits (154), Expect = 1.996e-10
Identity = 26/39 (66.67%), Postives = 35/39 (89.74%), Query Frame = 1

Query:  523 ALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            +LKWQQHQGLLPPG S+++FRGK A+++ E+E+ PTQLS
Sbjct:    3 SLKWQQHQGLLPPGMSLELFRGKGALKDMEEERFPTQLS 41

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
Match: smu1b (SMU1 DNA replication regulator and spliceosomal factor b [Source:ZFIN;Acc:ZDB-GENE-130530-635])

HSP 1 Score: 401.364 bits (1030), Expect = 6.533e-132
Identity = 181/303 (59.74%), Postives = 241/303 (79.54%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            G  SHVE A+FSPDGQYL+TG++DGFIEVWNF TGKI KDLKYQAQ+NFM+M++AVL L  S DS ++A+G+QDGKI+V+RI  G CL + E+AH K VTSV F++D T +LS SFD+++RIHG+KSGK LKEF+GHT+ VNDVIY+ D QH+ISAS+DGT+++W++KT + T   +      G +  ++ V+ VP+  + F++SN+TNTV + NI GQ++RSF +  R+G+DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  238 GPKSHVECARFSPDGQYLITGSVDGFIEVWNFTTGKICKDLKYQAQDNFMMMDEAVLCLAVSHDSHVIASGAQDGKIQVWRILNGTCLNRLERAHSKAVTSVCFNRDSTQLLSSSFDQTIRIHGLKSGKCLKEFRGHTAHVNDVIYSHDGQHVISASADGTVKVWTVKTMDCTHTIKTPDIPEGTDITVNNVVLVPKTPEHFVVSNRTNTVVVTNIHGQVMRSFCSGVREGADFVCCTLSPRGEWIYCVGEDYVLYCFS-TITGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 539

HSP 2 Score: 233.032 bits (593), Expect = 1.110e-67
Identity = 132/232 (56.90%), Postives = 169/232 (72.84%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQ--------------------------ALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M +E+ESADV+RLI QYLKENNL RTLA LQEET +SL+TVDS+++F+++I NG W++VL   Q LKLPD  LIDLYEQ+V+ELIEL ELG  + LL+QTDPMI++K  QPER++ +E LL   YFD ++AYP G +KEKRR AIA + A EV +VPPSRL+ LLGQ                          +LKWQQHQGLLPPG S+++FRGK A+++ E+E+ PTQLS
Sbjct:    1 MDLEVESADVIRLIMQYLKENNLHRTLAMLQEETTVSLHTVDSIDSFISDINNGQWDIVLLAIQYLKLPDKLLIDLYEQIVLELIELGELGAAQCLLKQTDPMIMLKHTQPERYSRMETLLTHPYFDSQKAYPVGSSKEKRRLAIAQAFAGEVCLVPPSRLMGLLGQGRICEGALYRLQETKALRQFGSLAMLSLKWQQHQGLLPPGMSLELFRGKGALKDMEEERFPTQLS 232

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
Match: wdr5 (WD repeat domain 5 [Source:ZFIN;Acc:ZDB-GENE-040426-2082])

HSP 1 Score: 136.346 bits (342), Expect = 8.127e-35
Identity = 85/305 (27.87%), Postives = 149/305 (48.85%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   42 AGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
Match: ppp6c (protein phosphatase 6, catalytic subunit [Source:Xenbase;Acc:XB-GENE-1017127])

HSP 1 Score: 428.713 bits (1101), Expect = 2.487e-143
Identity = 189/303 (62.38%), Postives = 251/303 (82.84%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++R+HG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  161 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDCSQILSASFDQTIRVHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 462

HSP 2 Score: 209.92 bits (533), Expect = 8.103e-60
Identity = 112/206 (54.37%), Postives = 132/206 (64.08%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            + I I S  V+RLI QYLKEN+L RTLATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLY                                                    +AYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG  ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 VTIHINSNFVIRLIMQYLKENSLHRTLATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLY---------------------------------------------------EQAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMIIDLFRGKAAVKDVEEEKFPTQLS 155

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
Match: ppp6c (protein phosphatase 6, catalytic subunit [Source:Xenbase;Acc:XB-GENE-1017127])

HSP 1 Score: 429.098 bits (1102), Expect = 8.181e-143
Identity = 189/303 (62.38%), Postives = 251/303 (82.84%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++R+HG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDCSQILSASFDQTIRVHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

HSP 2 Score: 288.886 bits (738), Expect = 7.799e-89
Identity = 159/206 (77.18%), Postives = 184/206 (89.32%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L RTLATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQNQPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG  ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRTLATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQNQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMIIDLFRGKAAVKDVEEEKFPTQLS 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
Match: ppp6c (protein phosphatase 6, catalytic subunit [Source:Xenbase;Acc:XB-GENE-1017127])

HSP 1 Score: 428.713 bits (1101), Expect = 1.118e-142
Identity = 189/303 (62.38%), Postives = 251/303 (82.84%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++R+HG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDCSQILSASFDQTIRVHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

HSP 2 Score: 278.1 bits (710), Expect = 1.249e-84
Identity = 155/206 (75.24%), Postives = 179/206 (86.89%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            + I I S  V+RLI QYLKEN+L RTLATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQNQPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG  ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 VTIHINSNFVIRLIMQYLKENSLHRTLATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQNQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMIIDLFRGKAAVKDVEEEKFPTQLS 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
Match: ppp4r1l (protein phosphatase 4 regulatory subunit 1 like (pseudogene) [Source:Xenbase;Acc:XB-GENE-5997807])

HSP 1 Score: 139.428 bits (350), Expect = 1.021e-35
Identity = 89/322 (27.64%), Postives = 157/322 (48.76%), Query Frame = 2

Query: 1142 EPWALLHKNLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             P++L+  N  +      G +  V   KFSP+G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED L+Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   24 SPFSLVKPNYTLKFTL-AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTCHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEVVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 329

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
Match: ppp4r1l (protein phosphatase 4 regulatory subunit 1 like (pseudogene) [Source:Xenbase;Acc:XB-GENE-5997807])

HSP 1 Score: 138.272 bits (347), Expect = 1.450e-35
Identity = 86/305 (28.20%), Postives = 150/305 (49.18%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP+G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED L+Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   17 AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTCHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEVVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 306

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
Match: Smu1 (smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) [Source:MGI Symbol;Acc:MGI:1915546])

HSP 1 Score: 431.795 bits (1109), Expect = 5.021e-144
Identity = 191/303 (63.04%), Postives = 252/303 (83.17%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 513

HSP 2 Score: 286.574 bits (732), Expect = 5.274e-88
Identity = 157/206 (76.21%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L R LATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG +ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLS 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
Match: Wdr5 (WD repeat domain 5 [Source:MGI Symbol;Acc:MGI:2155884])

HSP 1 Score: 137.502 bits (345), Expect = 3.863e-35
Identity = 86/305 (28.20%), Postives = 150/305 (49.18%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP+G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED L+Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   42 AGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
Match: Wdr5b (WD repeat domain 5B [Source:MGI Symbol;Acc:MGI:1916794])

HSP 1 Score: 127.102 bits (318), Expect = 1.193e-31
Identity = 82/304 (26.97%), Postives = 147/304 (48.36%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLW 2095
             G S+ +   KFSP+G++L +   D  I +W    G  +K L   + E        +  + +S DS  L + S D  +KV+ +++G+CLK   K H   V    F+     I+SGSFD+SV+I  +K+GK LK    H+  ++ V +  +   I+S S DG  R+W   +G+         L  +  P  + +    N    + +   NT+ + +  +G+ +++++  K +     A+      +W     ED ++Y +NLQ +  ++R +  H   VI    HP +N+IA+ A   D  +++W
Sbjct:   36 AGHSAAISSVKFSPNGEWLASSAADALIIIWGAYDGNCKKTLYGHSLE--------ISDVAWSSDSSRLVSASDDKTLKVWDMRSGKCLKTL-KGHSDFVFCCDFNPPSNLIVSGSFDESVKIWEVKTGKCLKTLSAHSDPISAVNFNCNGSLIVSGSYDGLCRIWDAASGQ-----CLRTLADEGNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCLFASFSVTGRKWVVSGSEDNMVYIWNLQTKEIVQR-LQGHTDVVISAACHPTKNIIASAALENDKTIKVW 324

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
Match: Wdr5 (WD repeat domain 5 [Source:MGI Symbol;Acc:MGI:2155884])

HSP 1 Score: 107.842 bits (268), Expect = 1.770e-25
Identity = 74/257 (28.79%), Postives = 126/257 (49.03%), Query Frame = 2

Query: 1370 LGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEG--------TIWRAYSGL---VGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
            + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         T     S L      + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED L+Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   24 VAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIVFVTSHEKRSPLRTPCDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 278

HSP 2 Score: 81.2629 bits (199), Expect = 1.877e-16
Identity = 53/192 (27.60%), Postives = 92/192 (47.92%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKK---FEKAHVK-------------GVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTS-----FVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            G S++V    F+P    +V+G+ D  + +W+  TGK  K L   +          V ++ F+RD  ++ + S DG  +++   +GQCLK    F  +H K              V+ V+FS +G  IL+ + D ++++     GK LK + GH +     F N  +     + I+S S D  + +W+L+T E
Sbjct:   58 GHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSD--------PVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIVFVTSHEKRSPLRTPCDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTG--GKWIVSGSEDNLVYIWNLQTKE 239

HSP 3 Score: 51.2174 bits (121), Expect = 2.014e-6
Identity = 30/119 (25.21%), Postives = 59/119 (49.58%), Query Frame = 2

Query: 1211 VEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSF--DKSVRI 1561
            V   KFSP+G+Y++  TLD  +++W++  GK  K       E + I     ++ G     + + +GS+D  + ++ +QT + ++K +  H   V S         I S +   DK++++
Sbjct:  164 VSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGG-----KWIVSGSEDNLVYIWNLQTKEIVQKLQ-GHTDVVISTACHPTENIIASAALENDKTIKL 276

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
Match: Katnb1 (katanin p80 (WD40-containing) subunit B 1 [Source:MGI Symbol;Acc:MGI:1921437])

HSP 1 Score: 102.064 bits (253), Expect = 5.480e-22
Identity = 62/208 (29.81%), Postives = 108/208 (51.92%), Query Frame = 2

Query: 1148 WALLHKNLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVM 1771
            W++   N  + L    G +S VE  + +   + +V G+  G I VW+    KI + L        M  +  + SL F    E +A+GSQD  IK++ I+   C+ ++ + H + V  ++FS DG  + S + D +V++  + +GK++ EF GHT  VN V + P+   + S SSD T+R W L+      ++  S + G+  P+ +V+
Sbjct:   48 WSINKPNCIMSLT---GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTL--------MGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRY-RGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEK-----FQVVSCIEGEPGPVRSVL 238

HSP 2 Score: 62.003 bits (149), Expect = 2.062e-9
Identity = 43/174 (24.71%), Postives = 87/174 (50.00%), Query Frame = 2

Query: 1178 ILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKD---LKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLW 1690
            IL   +G  +++    F P G+++ +G+ D  I++W+     IR+     +Y+         +AV  L FS D + LA+ + D  +K++ +  G+ + +F   H   V  V+F  +   + SGS D+++R   ++  +++   +G    V  V++ PD   + S   D +LR++
Sbjct:   97 ILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD-----IRRKGCVFRYRGHS------QAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD-SLRVY 257

HSP 3 Score: 54.299 bits (129), Expect = 5.603e-7
Identity = 55/212 (25.94%), Postives = 94/212 (44.34%), Query Frame = 2

Query: 1475 AHVKGVTSVQFSKDGTNIL-SGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNT---VAIINIQGQIVRSFSAPKRDGSDFVATI-ISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            AH   V+S+   K    +L +G  D  V +  +     +    GHTS V  V      + I++ S  G++R+W L+  +  I R    L+G +A I ++   P    +F+ S   +T   +  I  +G + R      R  S  V  +  SP G+W     +D  +  ++L A  K+    P H   V  +  HP++ L+A+ + D  +R W
Sbjct:   18 AHASNVSSLVLGKASGRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAK--ILRT---LMGHKANICSLDFHPYG--EFVASGSQDTNIKLWDIRRKGCVFR-----YRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTA-GKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFW 216

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
Match: sp|Q7ZVA0|SMU1_DANRE (WD40 repeat-containing protein SMU1 OS=Danio rerio OX=7955 GN=smu1 PE=2 SV=1)

HSP 1 Score: 433.335 bits (1113), Expect = 8.830e-144
Identity = 192/303 (63.37%), Postives = 249/303 (82.18%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL+++E+AH KGVT + FSKD T ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+    PD  H ISASSDGT+++W++KT E T  +++     G +  ++ V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMSFSRDTEMLATGAQDGKIKVWKIQSGQCLRRYERAHSKGVTCLSFSKDSTQILSASFDQTIRIHGLKSGKCLKEFRGHSSFVNEATLTPDGHHAISASSDGTVKVWNMKTTECTSTFKSLGTSAGTDITVNNVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDYVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

HSP 2 Score: 283.493 bits (724), Expect = 4.752e-86
Identity = 155/206 (75.24%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIESADV+RLI QYLKEN+L RTLA LQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQ+LKWQQHQGLLPPG +ID+FRGKAAV++ E+E+ PTQL+
Sbjct:    1 MSIEIESADVIRLIMQYLKENSLHRTLAMLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLA 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
Match: sp|Q3UKJ7|SMU1_MOUSE (WD40 repeat-containing protein SMU1 OS=Mus musculus OX=10090 GN=Smu1 PE=2 SV=2)

HSP 1 Score: 431.795 bits (1109), Expect = 3.512e-143
Identity = 191/303 (63.04%), Postives = 252/303 (83.17%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 513

HSP 2 Score: 286.574 bits (732), Expect = 3.689e-87
Identity = 157/206 (76.21%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L R LATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG +ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLS 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
Match: sp|Q2TAY7|SMU1_HUMAN (WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2)

HSP 1 Score: 431.795 bits (1109), Expect = 3.512e-143
Identity = 191/303 (63.04%), Postives = 252/303 (83.17%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 513

HSP 2 Score: 286.574 bits (732), Expect = 3.689e-87
Identity = 157/206 (76.21%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L R LATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG +ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLS 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
Match: sp|Q76B40|SMU1_CRIGR (WD40 repeat-containing protein SMU1 OS=Cricetulus griseus OX=10029 GN=SMU1 PE=1 SV=1)

HSP 1 Score: 431.795 bits (1109), Expect = 3.512e-143
Identity = 191/303 (63.04%), Postives = 252/303 (83.17%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 513

HSP 2 Score: 286.574 bits (732), Expect = 3.689e-87
Identity = 157/206 (76.21%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L R LATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG +ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLS 206

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BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
Match: sp|Q2TBS9|SMU1_BOVIN (WD40 repeat-containing protein SMU1 OS=Bos taurus OX=9913 GN=SMU1 PE=2 SV=1)

HSP 1 Score: 431.795 bits (1109), Expect = 3.512e-143
Identity = 191/303 (63.04%), Postives = 252/303 (83.17%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE A+FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT + FSKD + ILS SFD+++RIHG+KSGK LKEF+GH+SFVN+  +  D  +IISASSDGT+++W++KT E +  +++     G +  +++V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLIATY+EDGLL+LWKP
Sbjct:  212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP 513

HSP 2 Score: 286.574 bits (732), Expect = 3.689e-87
Identity = 157/206 (76.21%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IEIES+DV+RLI QYLKEN+L R LATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQALKWQQHQGLLPPG +ID+FRGKAAV++ E+EK PTQLS
Sbjct:    1 MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLS 206

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BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
Match: A0A183AXA3 (WD_REPEATS_REGION domain-containing protein OS=Echinostoma caproni OX=27848 GN=ECPE_LOCUS11588 PE=4 SV=1)

HSP 1 Score: 469.929 bits (1208), Expect = 1.234e-158
Identity = 210/304 (69.08%), Postives = 264/304 (86.84%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            VGQ  HVE A+FSPDGQ+LVTG++DGFIEVWNF TGK+RKDLKYQAQ+ FM+ME++VL L FSRDSEMLA+GS DGKIKV+RIQ+GQCL++FEKAH KGVT+VQFSKD T++LS SFD S+RIHG+KSGKL+KEF GHT+ VN V Y+PD  +IIS SSDG++R+WS+++GE T  ++A SGLVG+E  IH+V+PVPRN DQF++++++NTVAI+N+QGQ+VRSFS  KR+G DF+   +S +GEW YCV ED+LLYCFN+ A  KLERT+P+H+K+VIG  HHPHQNLIATY+EDGLLRLWKP
Sbjct:    3 VGQKCHVECARFSPDGQFLVTGSVDGFIEVWNFTTGKLRKDLKYQAQDTFMMMEESVLCLAFSRDSEMLASGSGDGKIKVWRIQSGQCLRRFEKAHSKGVTAVQFSKDSTHMLSASFDHSIRIHGLKSGKLIKEFLGHTAVVNSVGYSPDGHYIISGSSDGSVRVWSIRSGECTNTFKAISGLVGREVAIHSVIPVPRNADQFVVASRSNTVAIMNMQGQVVRSFSNGKREGGDFIDCCVSSRGEWIYCVAEDRLLYCFNVVAGGKLERTMPVHEKEVIGCAHHPHQNLIATYSEDGLLRLWKP 306

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BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
Match: A0A504Y7J8 (WD40 repeat-containing protein SMU1 OS=Fasciola gigantica OX=46835 GN=FGIG_04876 PE=4 SV=1)

HSP 1 Score: 465.692 bits (1197), Expect = 9.566e-154
Identity = 207/304 (68.09%), Postives = 262/304 (86.18%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            VGQ  HVE A+FSPDGQ+LVTG++DGFIEVWNF TGK+RKDLKYQAQ+ FM+ME +VL L FSRDSEMLA+GS DGK+KV+RIQ+GQCL++FEKAH KGVT+VQFSKD T++LS SFD S+RIHG+KSGKL+KEF GHT+ VN V + PD  +IIS SSDG++R+WS+++GE T  ++A SGLVG+E  IH+V+PVPRN DQF++++++NTVAI+N+QGQ+VRSFS  KR+G DF+   +S +GEW YCV ED+LLYCFN+ A  KLERT+P+H+K+VIG  HHPHQNLIATY+EDGLLR+WKP
Sbjct:  222 VGQKCHVECARFSPDGQFLVTGSVDGFIEVWNFTTGKLRKDLKYQAQDTFMMMEDSVLCLTFSRDSEMLASGSGDGKVKVWRIQSGQCLRRFEKAHSKGVTAVQFSKDSTHLLSASFDHSIRIHGLKSGKLIKEFLGHTAVVNSVGFTPDGHYIISGSSDGSVRVWSVRSGECTNTFKAISGLVGREVAIHSVIPVPRNADQFVVASRSNTVAIMNMQGQVVRSFSNGKREGGDFIDCCVSSRGEWIYCVAEDRLLYCFNVVAGGKLERTMPVHEKEVIGCAHHPHQNLIATYSEDGLLRIWKP 525

HSP 2 Score: 301.212 bits (770), Expect = 3.752e-90
Identity = 173/219 (79.00%), Postives = 188/219 (85.84%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPRE-----------AYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLSLT 645
            MAIEIESADVVRLIEQYLKE+NL RTL TLQEETGISLNTVDSVE FM+EIT+GHW+ VLQV QNLKLPD KL+DLYEQ+VIEL+ELRELG  RTLLRQTDPMI +K N P+RHAHLE LL RSYFDPRE           AY +GQ+KEKRRQAIA +L+ EVSVV PSRLLALLGQALKWQQHQGLLPPG++IDVFRGKAAVREQEDEK P QLS T
Sbjct:    1 MAIEIESADVVRLIEQYLKESNLTRTLQTLQEETGISLNTVDSVEGFMSEITSGHWDTVLQVVQNLKLPDHKLMDLYEQIVIELVELRELGAARTLLRQTDPMIALKHNYPDRHAHLENLLARSYFDPREVLVTLLKRLLKAYLDGQSKEKRRQAIATALSGEVSVVAPSRLLALLGQALKWQQHQGLLPPGTAIDVFRGKAAVREQEDEKPPAQLSTT 219

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BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
Match: A0A4E0RFF1 (WD40 repeat-containing protein SMU1 OS=Fasciola hepatica OX=6192 GN=D915_004313 PE=4 SV=1)

HSP 1 Score: 464.537 bits (1194), Expect = 3.042e-153
Identity = 207/304 (68.09%), Postives = 261/304 (85.86%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            VGQ  HVE A+FSPDGQ+LVTG++DGFIEVWNF TGK+RKDLKYQAQ+ FM+ME +VL L FSRDSEMLA+GS DGK+KV+RIQ+GQCL++FEKAH KGVT+VQFSKD T++LS SFD S+RIHG+KSGKL+KEF GHTS VN V + PD  +IIS SSDG++R+WS+++GE T  ++A SGLVG+E  IH+V+PVPRN DQF++++++N VAI+N+QGQ+VRSFS  KR+G DF+   +S +GEW YCV ED+LLYCFN+ A  KLERT+P+H+K+VIG  HHPHQNLIATY+EDGLLR+WKP
Sbjct:  222 VGQKCHVECARFSPDGQFLVTGSVDGFIEVWNFTTGKLRKDLKYQAQDTFMMMEDSVLCLTFSRDSEMLASGSGDGKVKVWRIQSGQCLRRFEKAHSKGVTAVQFSKDSTHLLSASFDHSIRIHGLKSGKLIKEFLGHTSVVNSVGFTPDGHYIISGSSDGSVRVWSVRSGECTNTFKAISGLVGREVAIHSVIPVPRNADQFVVASRSNIVAIMNMQGQVVRSFSNGKREGGDFIDCCVSSRGEWIYCVAEDRLLYCFNVVAGGKLERTMPVHEKEVIGCAHHPHQNLIATYSEDGLLRIWKP 525

HSP 2 Score: 301.212 bits (770), Expect = 4.349e-90
Identity = 173/219 (79.00%), Postives = 188/219 (85.84%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPRE-----------AYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLSLT 645
            MAIEIESADVVRLIEQYLKE+NL RTL TLQEETGISLNTVDSVE FM+EIT+GHW+ VLQV QNLKLPD KL+DLYEQ+VIEL+ELRELG  RTLLRQTDPMI +K N P+RHAHLE LL RSYFDPRE           AY +GQ+KEKRRQAIA +L+ EVSVV PSRLLALLGQALKWQQHQGLLPPG++IDVFRGKAAVREQEDEK P QLS T
Sbjct:    1 MAIEIESADVVRLIEQYLKESNLTRTLQTLQEETGISLNTVDSVEGFMSEITSGHWDTVLQVVQNLKLPDHKLMDLYEQIVIELVELRELGAARTLLRQTDPMIALKHNYPDRHAHLENLLARSYFDPREVLVILLKRLLKAYLDGQSKEKRRQAIATALSGEVSVVAPSRLLALLGQALKWQQHQGLLPPGTAIDVFRGKAAVREQEDEKPPAQLSTT 219

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BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
Match: A0A183TJ06 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 PE=4 SV=1)

HSP 1 Score: 462.611 bits (1189), Expect = 8.172e-153
Identity = 201/304 (66.12%), Postives = 261/304 (85.86%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEG-TIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            +GQ SHVE A FSPDGQYLVTG++DGFIEVWNF+TGK+RKDL+YQAQENFM+ME+AVL L FSRDSE+LA+GSQDGK+K++RIQ+GQCL++F+KAHVKGVT+  FSKD  ++L+ SFD ++RIHG+KSG LLKEF GHT FVNDV +  D  H++S SSDG++R+WS++T E    ++A SGLVG+E P+  V P+PRNT+QF++ +++NTVAI+N+QGQ+VRSF+  KR+G DF+A  +S +GEW YCV ED+LLYCFN+ A  +LERT+P+H+K+VIGL HHPHQNLIAT++EDGLLRLWKP
Sbjct:  199 LGQKSHVECALFSPDGQYLVTGSVDGFIEVWNFITGKLRKDLRYQAQENFMMMEEAVLCLAFSRDSELLASGSQDGKVKIWRIQSGQCLRRFDKAHVKGVTAAHFSKDNVHLLTASFDHTIRIHGLKSGNLLKEFIGHTGFVNDVTFTMDGHHVLSGSSDGSVRVWSVRTTECINTFKAISGLVGREVPVQCVQPMPRNTEQFVVCSRSNTVAIMNMQGQVVRSFTNGKREGGDFIACSVSSRGEWIYCVCEDRLLYCFNVAAGGRLERTLPVHEKEVIGLAHHPHQNLIATFSEDGLLRLWKP 502

HSP 2 Score: 285.034 bits (728), Expect = 3.313e-84
Identity = 160/194 (82.47%), Postives = 178/194 (91.75%), Query Frame = 1

Query:   58 LIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            LIEQYLKE+NL+RTL  LQEETGISLNTVDSVE+FM+EIT+GHW+ VL+V QNLKL D KL+DLYEQ+VIELIELRELG  RTLLRQTDPMIL+KQN P+R+ HLE LL RSYFDPREAY EGQTKEKRRQAIA +L+ EVSVVPPSRLLALLGQA+KWQQHQGLLPPG++IDVFRGKAAVREQE+EK PTQLS
Sbjct:    1 LIEQYLKESNLIRTLQVLQEETGISLNTVDSVESFMSEITSGHWDTVLKVVQNLKLADHKLMDLYEQIVIELIELRELGAARTLLRQTDPMILLKQNHPDRYVHLENLLARSYFDPREAYLEGQTKEKRRQAIASALSGEVSVVPPSRLLALLGQAVKWQQHQGLLPPGTAIDVFRGKAAVREQEEEKPPTQLS 194

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BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
Match: A0A3P7CY36 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=SSLN_LOCUS16454 PE=4 SV=1)

HSP 1 Score: 462.611 bits (1189), Expect = 8.626e-153
Identity = 201/304 (66.12%), Postives = 261/304 (85.86%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEG-TIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            +GQ SHVE A FSPDGQYLVTG++DGFIEVWNF+TGK+RKDL+YQAQENFM+ME+AVL L FSRDSE+LA+GSQDGK+K++RIQ+GQCL++F+KAHVKGVT+  FSKD  ++L+ SFD ++RIHG+KSG LLKEF GHT FVNDV +  D  H++S SSDG++R+WS++T E    ++A SGLVG+E P+  V P+PRNT+QF++ +++NTVAI+N+QGQ+VRSF+  KR+G DF+A  +S +GEW YCV ED+LLYCFN+ A  +LERT+P+H+K+VIGL HHPHQNLIAT++EDGLLRLWKP
Sbjct:  199 LGQKSHVECALFSPDGQYLVTGSVDGFIEVWNFITGKLRKDLRYQAQENFMMMEEAVLCLAFSRDSELLASGSQDGKVKIWRIQSGQCLRRFDKAHVKGVTAAHFSKDNVHLLTASFDHTIRIHGLKSGNLLKEFIGHTGFVNDVTFTMDGHHVLSGSSDGSVRVWSVRTTECINTFKAISGLVGREVPVQCVQPMPRNTEQFVVCSRSNTVAIMNMQGQVVRSFTNGKREGGDFIACSVSSRGEWIYCVCEDRLLYCFNVAAGGRLERTLPVHEKEVIGLAHHPHQNLIATFSEDGLLRLWKP 502

HSP 2 Score: 284.263 bits (726), Expect = 6.848e-84
Identity = 159/194 (81.96%), Postives = 178/194 (91.75%), Query Frame = 1

Query:   58 LIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            +IEQYLKE+NL+RTL  LQEETGISLNTVDSVE+FM+EIT+GHW+ VL+V QNLKL D KL+DLYEQ+VIELIELRELG  RTLLRQTDPMIL+KQN P+R+ HLE LL RSYFDPREAY EGQTKEKRRQAIA +L+ EVSVVPPSRLLALLGQA+KWQQHQGLLPPG++IDVFRGKAAVREQE+EK PTQLS
Sbjct:    1 MIEQYLKESNLIRTLQVLQEETGISLNTVDSVESFMSEITSGHWDTVLKVVQNLKLADHKLMDLYEQIVIELIELRELGAARTLLRQTDPMILLKQNHPDRYVHLENLLARSYFDPREAYLEGQTKEKRRQAIASALSGEVSVVPPSRLLALLGQAVKWQQHQGLLPPGTAIDVFRGKAAVREQEEEKPPTQLS 194

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
Match: smu1a (SMU1 DNA replication regulator and spliceosomal factor a [Source:NCBI gene;Acc:393168])

HSP 1 Score: 405.216 bits (1040), Expect = 9.482e-135
Identity = 183/303 (60.40%), Postives = 241/303 (79.54%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            GQ SHVE ++FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL + FSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT V FSKD + +LS SFD+++R+HG+KSGK LKEF+GH+SFVN+  + PD  HIISASSDGT+++W++KT E T  +++     G +  ++ V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+                GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI+TY+EDGLL+LWKP
Sbjct:  161 GQKSHVECSRFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCVSFSKDSSQLLSASFDQTIRVHGLKSGKSLKEFRGHSSFVNEATFTPDGHHIISASSDGTVKIWNVKTTECTSTFKSLGASAGTDITVNNVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSS----------------GEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLISTYSEDGLLKLWKP 446

HSP 2 Score: 222.631 bits (566), Expect = 7.113e-65
Identity = 115/206 (55.83%), Postives = 138/206 (66.99%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M++EIESADV+RLI QYLKENNL RTLATLQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLY                                                    +AYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQ+LKWQQHQGLLPPG +ID+FRGKAAV++ E+E+ PTQLS
Sbjct:    1 MSLEIESADVIRLIMQYLKENNLHRTLATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLY---------------------------------------------------EQAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLS 155

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
Match: smu1b (WD40 repeat-containing protein SMU1-like [Source:NCBI gene;Acc:103030615])

HSP 1 Score: 384.8 bits (987), Expect = 1.653e-125
Identity = 173/304 (56.91%), Postives = 239/304 (78.62%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE--GTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            G  +HVE A+FSPDGQYL+TG++DG+IEVW+F TGKI KDLKYQ+Q+NFM+ME+AVL L  S D+EM+A+G+QDG+I+V+RI  GQCL+KFE+AH K VT + FSKD + +LS SFD+ +RIHG+KSGK+LKEF+GH S +ND+ ++ +  +IISAS+DG++++W+ KT +   TI +      G +  ++ V+ VPRN + F++ N+T+TV ++NI GQ++RSFS   R+G DFV   +SP+GEW YCVGED +LY F+     KLERT+ +H+KDVIG+ HHPH NLIATY+EDGLL+LWKP
Sbjct:  238 GPKTHVECARFSPDGQYLITGSVDGYIEVWDFTTGKICKDLKYQSQDNFMMMEEAVLCLAVSSDTEMVASGAQDGQIQVWRIHNGQCLRKFERAHSKAVTCICFSKDNSQLLSASFDQIIRIHGLKSGKMLKEFRGHASCINDITFSHNGHYIISASADGSVKVWNAKTTDCINTI-KTPDVPEGADITVNNVVLVPRNPEHFVVCNRTSTVVVMNIHGQVLRSFSTGVREGGDFVCCTLSPRGEWIYCVGEDFVLYSFS-TITGKLERTLTVHEKDVIGITHHPHNNLIATYSEDGLLKLWKP 539

HSP 2 Score: 242.662 bits (618), Expect = 2.777e-71
Identity = 140/232 (60.34%), Postives = 174/232 (75.00%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQ--------------------------ALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M +++E+ADV+RLI QYLKENNL RTLA LQEET +SL+TVDS+++F+A+I +GHW+VVL   Q LKLPD  LIDLYEQVV+ELIELRELG  + LL QTDPMI+MK  QPER++ LEALL+  +FD +EAYPE   K+KRRQAIA ++A EVS+VPPSRL+ LLGQ                          +LKWQQHQGLLPPG SID+FRGKA +++ E+E+ PTQLS
Sbjct:    1 MELDVETADVIRLIMQYLKENNLHRTLAALQEETTVSLHTVDSIDSFIADINDGHWDVVLLAIQYLKLPDKLLIDLYEQVVLELIELRELGAAQCLLAQTDPMIMMKHTQPERYSKLEALLLSPHFDSKEAYPESSDKDKRRQAIAQAMAKEVSLVPPSRLMGLLGQGRICEGALYRLQETKALRQFGSLAVLSLKWQQHQGLLPPGMSIDLFRGKAMMKDLEEERFPTQLS 232

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
Match: wdr5 (WD repeat domain 5 [Source:NCBI gene;Acc:103033424])

HSP 1 Score: 136.346 bits (342), Expect = 6.315e-35
Identity = 85/305 (27.87%), Postives = 149/305 (48.85%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   42 AGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
Match: ENSAMXT00000007963.2 (WD repeat-containing protein 5-like [Source:NCBI gene;Acc:103023146])

HSP 1 Score: 134.42 bits (337), Expect = 2.560e-34
Identity = 84/305 (27.54%), Postives = 150/305 (49.18%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  +   KFSP+G++L + + D  I++W    GK  K L           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     ++SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   39 AGHTKAISSVKFSPNGEWLASSSADKLIKIWGSFDGKFEKSLSGH--------KLGISDVAWSPDSNLLVSASDDKTLKIWDMGSGKCLKTL-KGHSNYVFCCNFNPQSNLVVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRMWDSTSGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCVFANFSVTGGKWIVSGSEDHMVYIWNLQTKEIVQK-LQGHADVVIATACHPSENIIASAALENDKTIKLWK 328

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
Match: wdr5 (WD repeat domain 5 [Source:NCBI gene;Acc:103033424])

HSP 1 Score: 118.242 bits (295), Expect = 9.828e-29
Identity = 83/305 (27.21%), Postives = 141/305 (46.23%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S    L  W                     P+  V   P N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   42 AGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSPQLLLFNWD----------------DDNPPVSFVKFSP-NGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 319

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002506.1 (pep scaffold:Pmarinus_7.0:GL479076:26529:32136:-1 gene:ENSPMAG00000002224.1 transcript:ENSPMAT00000002506.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 87.8113 bits (216), Expect = 3.316e-19
Identity = 55/174 (31.61%), Postives = 85/174 (48.85%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKF-EKAHVKGVTSVQFSKDGTN--ILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            G    V     S DGQ+ ++G+ DG + +W+  TG   +         F+   K VLS+ FS D+  + +GS+D  IK++    G C     E  H + V+ V+FS +  N  I+S  +DK V++  + + KL     GHT ++N V  +PD     S   DG   LW L  G+
Sbjct:   61 GHGHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTR--------RFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWNT-LGVCKYTIQEDGHTEWVSCVRFSPNNNNPIIVSCGWDKLVKVWNLTNCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGK 225

HSP 2 Score: 58.151 bits (139), Expect = 2.067e-9
Identity = 31/105 (29.52%), Postives = 58/105 (55.24%), Query Frame = 2

Query: 1391 EMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKG----VTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWS 1693
            +M+ + S+D  + ++++   +      +  + G    V+ V  S DG   LSGS+D ++R+  + +G   + F GHT  V  V ++ DN+ I+S S D T++LW+
Sbjct:   29 DMILSASRDKTLIMWKLTRDETNYGIPQRSLHGHGHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSADNRQIVSGSRDKTIKLWN 133

HSP 3 Score: 54.6842 bits (130), Expect = 2.960e-8
Identity = 59/202 (29.21%), Postives = 92/202 (45.54%), Query Frame = 2

Query: 1526 ILSGSFDKSVRIHGMKS-----GKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHT--VMPVPRNTD--QFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATI-ISPKGE--WFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            ILS S DK++ +  +       G   +   GH  FV+DV+ + D Q  +S S DGTLRLW L TG  T  R + G        HT  V+ V  + D  Q +  ++  T+ + N  G  V  ++  +   +++V+ +  SP          G DKL+  +NL    KL+     H   +  +   P  +L A+  +DG   LW
Sbjct:   31 ILSASRDKTLIMWKLTRDETNYGIPQRSLHGHGHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTT--RRFVG--------HTKDVLSVAFSADNRQIVSGSRDKTIKLWNTLG--VCKYTIQEDGHTEWVSCVRFSPNNNNPIIVSCGWDKLVKVWNL-TNCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLW 219

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
Match: pafah1b1b (platelet-activating factor acetylhydrolase 1b, regulatory subunit 1b [Source:NCBI gene;Acc:394247])

HSP 1 Score: 85.8853 bits (211), Expect = 2.305e-18
Identity = 75/300 (25.00%), Postives = 126/300 (42.00%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            G  S V    F P    +V+ + D  I+VW++ TG   + LK            +V  + F    +MLA+ S D  +K++  Q+ +CL+     H   V+SV F  +G +++S S DK++++  +++G  +K F GH  +V  V    D   I S S+D T+R+W   T E       + L   E  +  V   P             +  I+   G   +    P               G +      DK +  +++ +      T+  HD  V G++ HP    I + A+D  LR+W
Sbjct:   45 GHRSPVTRVIFHPVFSVIVSASEDATIKVWDYETGDFERTLKGHTD--------SVQDISFDLSGKMLASCSADMTVKLWDFQSFECLRTMH-GHDHNVSSVAFMPNGDHLVSASRDKTMKMWEVQTGYCVKTFTGHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKE-----CKAELREHEHVVECVSWAP----------DAASPVILEATGAEAKKGGKP---------------GPYLLSGSRDKTIKMWDI-STGICVITLVGHDNWVRGVLFHPGGKFILSCADDKTLRVW 304

HSP 2 Score: 68.5514 bits (166), Expect = 1.164e-12
Identity = 47/187 (25.13%), Postives = 85/187 (45.45%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKF-EKAHV------------------KGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLK 1699
            G   +V    F P+G +LV+ + D  +++W   TG   K         F    + V  +  ++D  ++A+ S D  ++V+   T +C  +  E  HV                   G  + +  K G  +LSGS DK++++  + +G  +    GH ++V  V++ P  + I+S + D TLR+W  K
Sbjct:  129 GHDHNVSSVAFMPNGDHLVSASRDKTMKMWEVQTGYCVK--------TFTGHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKECKAELREHEHVVECVSWAPDAASPVILEATGAEAKKGGKPGPYLLSGSRDKTIKMWDISTGICVITLVGHDNWVRGVLFHPGGKFILSCADDKTLRVWDYK 307

HSP 3 Score: 55.4546 bits (132), Expect = 2.181e-8
Identity = 40/180 (22.22%), Postives = 76/180 (42.22%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQ------------AQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLK 1699
            G    V + + + DG  + + + D  + VW   T + + +L+              A    ++      +    +    L +GS+D  IK++ I TG C+      H   V  V F   G  ILS + DK++R+   K+ +  K    H  FV  + +     ++I+ S D ++++W  +
Sbjct:  171 GHREWVRMVRPNQDGSLIASCSNDQTVRVWVTATKECKAELREHEHVVECVSWAPDAASPVILEATGAEAKKGGKPGPYLLSGSRDKTIKMWDISTGICVITL-VGHDNWVRGVLFHPGGKFILSCADDKTLRVWDYKNKRCQKSLAAHEHFVTSLDFHKTAPYVITGSVDQSVKVWECR 349

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BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
Match: wdr61 (WD repeat domain 61 [Source:NCBI gene;Acc:393827])

HSP 1 Score: 82.4185 bits (202), Expect = 1.842e-17
Identity = 49/147 (33.33%), Postives = 76/147 (51.70%), Query Frame = 2

Query: 1226 FSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEK----AHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHI 1654
            FSPD ++L TG+  G I ++   +GK    L  +         K +LSL +S D + LA+G+ DG I +F I TG+ L   E      H   + S+ FS D   +++ S D  ++I+ ++  KL     GH S+V +V + PDN H 
Sbjct:  114 FSPDSRFLSTGSHMGKINIFGIESGKKESTLDTRG--------KFILSLAYSPDGKHLASGAIDGIINIFDISTGKLLHTLEAWARGGHAMPIRSLTFSPDSQLLITASDDGYIKIYDVQHAKLAATLSGHASWVLNVSFCPDNTHF 252

HSP 2 Score: 76.2554 bits (186), Expect = 2.742e-15
Identity = 53/195 (27.18%), Postives = 94/195 (48.21%), Query Frame = 2

Query: 1226 FSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKG--VTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFK-----GHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNT 1789
             SP G    + +LD  + +W+   G   K +     + +        S+ FS DS  L+ GS  GKI +F I++G   KK      +G  + S+ +S DG ++ SG+ D  + I  + +GKLL   +     GH   +  + ++PD+Q +I+AS DG ++++ ++       +  + L G  + +  V   P NT
Sbjct:   72 ISPTGALAASSSLDANLRLWDLECGSELKTIDAGPVDAW--------SVAFSPDSRFLSTGSHMGKINIFGIESG---KKESTLDTRGKFILSLAYSPDGKHLASGAIDGIINIFDISTGKLLHTLEAWARGGHAMPIRSLTFSPDSQLLITASDDGYIKIYDVQHA-----KLAATLSGHASWVLNVSFCPDNT 250

HSP 3 Score: 64.6994 bits (156), Expect = 1.658e-11
Identity = 46/199 (23.12%), Postives = 91/199 (45.73%), Query Frame = 2

Query: 1247 LVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQ 1843
            ++TG++D  ++ W +       D K + Q      +  V+S+  S    + A+ S D  ++++ ++ G  LK  +   V    SV FS D   + +GS    + I G++SGK          F+  + Y+PD +H+ S + DG + ++ + TG+           G   PI ++   P ++   I ++    + I ++Q
Sbjct:   35 IITGSVDDLVKCWKWA------DEKLELQWTLEGHQLGVVSVDISPTGALAASSSLDANLRLWDLECGSELKTIDAGPVDAW-SVAFSPDSRFLSTGSHMGKINIFGIESGKKESTLDTRGKFILSLAYSPDGKHLASGAIDGIINIFDISTGKLLHTLEAWARGGHAMPIRSLTFSP-DSQLLITASDDGYIKIYDVQ 225

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
Match: POC1A (POC1 centriolar protein A [Source:HGNC Symbol;Acc:HGNC:24488])

HSP 1 Score: 83.9593 bits (206), Expect = 2.574e-17
Identity = 72/304 (23.68%), Postives = 136/304 (44.74%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQE-NFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQ-GQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWK 2098
            G    +    F+P+ + L +G++D  + VWNF         K Q +   F+  + AV+S+ FS    ++ + S+D  ++++ + + +      KAH   V SV FS DG ++++ S DKS+++  +   K L     H+++V    ++PD + I+S S D T+R+W   + E    +  + G V Q    H     P  T     +   NTV + +I+  ++++ +      G+   +    P G +      D  L   +L  E +L  T+  H      +      +  A+   D  + +WK
Sbjct:   16 GHRDTITSVDFNPNMKQLASGSMDACLMVWNF---------KPQTRAYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLW-VPSVKGESTVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNSRECVHTFYEHGGFVNQ-VDFH-----PSGT-CIAAAGTDNTVKVWDIRMNKLLQHYQV---HGAAVNSLSFHPTGNYLITASNDSTLKVLDL-VEGRLFYTLHGHQGPATAVAFSRAGDFFASGGSDEQVMVWK 298

HSP 2 Score: 79.7221 bits (195), Expect = 5.896e-16
Identity = 62/214 (28.97%), Postives = 97/214 (45.33%), Query Frame = 2

Query: 1088 HFDGLRFQV*SPNINFREEPWALLHKNLCIIL-NF*--------VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVW-NFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLK 1699
            HF G R  + S + N   +  A    + C+++ NF         VG    V   +FSP G  +V+ + D  + +W   V G+            F      V S+ FS D + L   S D  IKV+ +   + L    + H   V S +FS DG  I+SGS D++VR+    S + +  F  H  FVN V + P    I +A +D T+++W ++
Sbjct:   13 HFKGHRDTITSVDFNPNMKQLASGSMDACLMVWNFKPQTRAYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVKGE---------STVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQKFLYSLNQ-HSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNSRECVHTFYEHGGFVNQVDFHPSGTCIAAAGTDNTVKVWDIR 216

HSP 3 Score: 58.5362 bits (140), Expect = 3.017e-9
Identity = 65/256 (25.39%), Postives = 107/256 (41.80%), Query Frame = 2

Query: 1430 VFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLW--SLKTGEGTIWRAYSGLV--------GQEAPIHT------VMPVPRNTDQFIISNKTNTV--AIINIQGQI---------VRSFSAPKRDG-------SDFVATI-ISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRL 2092
            V   Q    L++  K H   +TSV F+ +   + SGS D  + +   K       F GH   V  V ++P    ++SAS D T+RLW  S+K GE T+++A++  V        GQ     +      V  V R    + ++  +N V  A  +  G++         VR + +  R+          FV  +   P G      G D  +  ++++  NKL +   +H   V  L  HP  N + T + D  L++
Sbjct:    1 VLPWQEDPSLERHFKGHRDTITSVDFNPNMKQLASGSMDACLMVWNFKPQTRAYRFVGHKDAVMSVQFSPSGHLVVSASRDKTVRLWVPSVK-GESTVFKAHTATVRSVSFSADGQSLVTASDDKSIKVWTVHRQKFLYSLNQHSNWVRSAKFSPDGRLIVSGSDDRTVRVWDSNSRECVHTFYEHGGFVNQVDFHPSGTCIAAAGTDNTVKVWDIRM-NKLLQHYQVHGAAVNSLSFHPTGNYLITASNDSTLKV 254

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008862.1 (pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 gene:ENSPMAG00000008000.1 transcript:ENSPMAT00000008862.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 80.1073 bits (196), Expect = 6.258e-16
Identity = 80/309 (25.89%), Postives = 139/309 (44.98%), Query Frame = 2

Query: 1118 SPNINFREEPW--ALLHKNLCIILNF*VGQSSHVEVAKFSPD---------GQYLVTGTLDGFIEVWNFVTGKIRKDL--------KYQAQENFMIMEKAVLSLG-FSRDS---------------------EMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQ-GQIVRSFSAPKRDGSDFVATIISPK 1918
            S   NF   PW  A + ++  I +N+  G+    +V K   D         G  +V+G+ D  ++VW+ VTGK  + L          Q + N ++      +L  ++ D+                       + +GS+D  ++V+ I+TGQCL      HV  V  VQ+  DG  ++SG++D +V++   +S   L   +GHT+ V  + +  D  HI+S S D ++R+W  +TG          LVG ++ + + M +  N    +  N  +TV I +I+ GQ +++   P +  S       S K
Sbjct:  194 SATPNFTYSPWKSAYMRQHR-IDMNWRCGEIRAPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGKCLRTLVGHTGGVWSSQMRGNIIVSGSTDRTLKVWNADTGQCVHTLYGHTSTVRCMHLHGNRVVSGSRDATLRVWDIETGQCLHVL-AGHVAAVRCVQY--DGRRVVSGAYDYTVKVWDPESETCLHTLQGHTNRVYSLQF--DGVHIVSGSLDTSIRVWDAETGT-----CLHTLVGHQS-LTSGMELRDNI--LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFSRK 488

HSP 2 Score: 60.4622 bits (145), Expect = 7.558e-10
Identity = 55/181 (30.39%), Postives = 94/181 (51.93%), Query Frame = 2

Query: 1178 ILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNIL-SGSFDKSVRIHGMKSGKLLKEFKG---HTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
             L+   G  + V   ++  DG+ +V+G  D  ++VW+  +      L  Q   N       V SL F  D   + +GS D  I+V+  +TG CL      H + +TS    +D  NIL SG+ D +V+I  +K+G+ L+  +G   H S V  + ++   + ++++S DGT++LW L+TG+
Sbjct:  346 CLHVLAGHVAAVRCVQY--DGRRVVSGAYDYTVKVWDPESETCLHTL--QGHTN------RVYSLQF--DGVHIVSGSLDTSIRVWDAETGTCLHTL-VGH-QSLTSGMELRD--NILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFS--RKLVVTSSDDGTVKLWDLRTGD 508

HSP 3 Score: 57.7658 bits (138), Expect = 6.008e-9
Identity = 38/136 (27.94%), Postives = 69/136 (50.74%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFE--KAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEF 1597
            G ++ V   +F  DG ++V+G+LD  I VW+  TG     L          +    L+ G      +L +G+ D  +K++ I+TGQCL+  +    H   VT +QFS+    +++ S D +V++  +++G  L+  
Sbjct:  392 GHTNRVYSLQF--DGVHIVSGSLDTSIRVWDAETGTCLHTL----------VGHQSLTSGMELRDNILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFSRK--LVVTSSDDGTVKLWDLRTGDFLRNL 513

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
Match: PFS2 (Integral subunit of the pre-mRNA CPF complex; the cleavage and polyadenylation factor (CPF) complex plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex [Source:SGD;Acc:S000005261])

HSP 1 Score: 85.8853 bits (211), Expect = 3.839e-18
Identity = 72/301 (23.92%), Postives = 138/301 (45.85%), Query Frame = 2

Query: 1211 VEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPV---PRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVG-EDKLLYCFN-LQAENKLERTIPI-HDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            +   +++P+G+ LV  T  G   +WN  +        +  +      + AV ++ +S DS+ + +G  DG IK+++      +K+ + AH + +  + FS + +  ++ S D  ++I    +GK  +   GH   V    + P+   I SAS D  ++LW  ++G        S ++  +   HTV+     P   +  +  +K  +  + +I+  +        RD +D++     P  E  + +   D  L  F+ LQ  N+   TIP  HDK +  L ++P  ++ AT A+D  +R W
Sbjct:   96 IPAIQWTPEGRRLVVATYSGEFSLWNASS--------FTFETLMQAHDSAVTTMKYSHDSDWMISGDADGMIKIWQPNFSM-VKEIDAAHTESIRDMAFSSNDSKFVTCSDDNILKIWNFSNGKQERVLSGHHWDVKSCDWHPEMGLIASASKDNLVKLWDPRSGN-----CISSILKFK---HTVLKTRFQPTKGNLLMAISKDKSCRVFDIRYSMKELMCV--RDETDYMTLEWHPINESMFTLACYDGSLKHFDLLQNLNEPILTIPYAHDKCITSLSYNPVGHIFATAAKDRTIRFW 377

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
Match: TUP1 (General repressor of transcription; forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes [Source:SGD;Acc:S000000680])

HSP 1 Score: 83.9593 bits (206), Expect = 3.337e-17
Identity = 53/171 (30.99%), Postives = 88/171 (51.46%), Query Frame = 2

Query: 1226 FSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIM---EKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSK-DGTNILSGSFDKSVRIHGMKSGKLLKEFK-------GHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTG 1705
            FSPDG++L TG  D  I +W+    KI            MI+   E+ + SL +    + L +GS D  ++++ ++TGQC      +   GVT+V  S  DG  I +GS D++VR+   ++G L++          GH   V  V++  D Q ++S S D +++LW+L+  
Sbjct:  451 FSPDGKFLATGAEDRLIRIWDIENRKI-----------VMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQC--SLTLSIEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNA 608

HSP 2 Score: 74.3294 bits (181), Expect = 3.462e-14
Identity = 53/205 (25.85%), Postives = 97/205 (47.32%), Query Frame = 2

Query: 1148 WALLHKNLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSR-DSEMLAAGSQDGKIKVFRIQTGQCLKKFEK------AHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMK------------SGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTG 1705
            W + ++ + +IL    G    +    + P G  LV+G+ D  + +W+  TG+    L          +E  V ++  S  D + +AAGS D  ++V+  +TG  +++ +        H   V SV F++DG +++SGS D+SV++  ++            SG     + GH  FV  V    ++++I+S S D  +  W  K+G
Sbjct:  470 WDIENRKIVMILQ---GHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSLTLS---------IEDGVTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSENESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTYIGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSG 662

HSP 3 Score: 61.6178 bits (148), Expect = 2.601e-10
Identity = 53/182 (29.12%), Postives = 84/182 (46.15%), Query Frame = 2

Query: 1211 VEVAKFSP-DGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQ------------TGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYA------PDNQHIISASSDGTLRLWSLK 1699
            V     SP DG+Y+  G+LD  + VW+  TG + + L  +  E+    + +V S+ F+RD + + +GS D  +K++ +Q            +G C   +   H   V SV  +++   ILSGS D+ V     KSG  L   +GH + V  V  A      P+     + S D   R+W  K
Sbjct:  529 VTTVAVSPGDGKYIAAGSLDRAVRVWDSETGFLVERLDSE-NESGTGHKDSVYSVVFTRDGQSVVSGSLDRSVKLWNLQNANNKSDSKTPNSGTCEVTY-IGHKDFVLSVATTQNDEYILSGSKDRGVLFWDKKSGNPLLMLQGHRNSVISVAVANGSPLGPEYNVFATGSGDCKARIWKYK 708

HSP 4 Score: 51.9878 bits (123), Expect = 2.735e-7
Identity = 24/76 (31.58%), Postives = 46/76 (60.53%), Query Frame = 2

Query: 1490 VTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTI 1717
            + SV FS DG  + +G+ D+ +RI  +++ K++   +GH   +  + Y P    ++S S D T+R+W L+TG+ ++
Sbjct:  446 IRSVCFSPDGKFLATGAEDRLIRIWDIENRKIVMILQGHEQDIYSLDYFPSGDKLVSGSGDRTVRIWDLRTGQCSL 521

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
Match: ASC1 (G-protein beta subunit and guanine dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; required to prevent frameshifting at ribosomes stalled at repeated CGA codons; regulates P-body formation induced by replication stress; represses Gcn4p in the absence of amino acid starvation [Source:SGD;Acc:S000004722])

HSP 1 Score: 76.2554 bits (186), Expect = 1.855e-15
Identity = 65/231 (28.14%), Postives = 104/231 (45.02%), Query Frame = 2

Query: 1454 CLKKFEKAHVKGVTSVQFSKDGTNIL-SGSFDKSV---RIHG--MKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSF-----------SAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
             L+   + H   VTS+  S    N+L S S DK++   ++ G   K G  ++ FKGH+  V D     D  + +SAS D TLRLW + TGE      Y   VG ++ + +V  + +     I  ++  T+ +  I+GQ + +              P     D   TIIS         G DK++  +NL  + ++E     H+ ++  L   P   LIA+  +DG + LW
Sbjct:    8 VLRGTLEGHNGWVTSLATSAGQPNLLLSASRDKTLISWKLTGDDQKFGVPVRSFKGHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGE-----TYQRFVGHKSDVMSV-DIDKKASMIISGSRDKTIKVWTIKGQCLATLLGHNDWVSQVRVVPNEKADDDSVTIIS--------AGNDKMVKAWNLN-QFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLW 223

HSP 2 Score: 75.8702 bits (185), Expect = 2.014e-15
Identity = 50/172 (29.07%), Postives = 85/172 (49.42%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEK-----AHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSL 1696
            G S  V+    + DG Y ++ + D  + +W+  TG+      YQ    F+  +  V+S+   + + M+ +GS+D  IKV+ I+ GQCL          + V+ V + +   D   I+S   DK V+   +   ++  +F GH S +N +  +PD   I SA  DG + LW+L
Sbjct:   63 GHSHIVQDCTLTADGAYALSASWDKTLRLWDVATGET-----YQ---RFVGHKSDVMSVDIDKKASMIISGSRDKTIKVWTIK-GQCLATLLGHNDWVSQVRVVPNEKADDDSVTIISAGNDKMVKAWNLNQFQIEADFIGHNSNINTLTASPDGTLIASAGKDGEIMLWNL 225

HSP 3 Score: 49.2914 bits (116), Expect = 1.011e-6
Identity = 36/130 (27.69%), Postives = 55/130 (42.31%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKK-------FEKAHVKGVTSVQFSKDGTNILSGSFDKSVRI 1561
            +G +S++     SPDG  + +   DG I +WN    K    L  Q +         V SL FS +   LAA +  G IKVF +     +         + KA      S+ +S DG  + +G  D  +R+
Sbjct:  193 IGHNSNINTLTASPDGTLIASAGKDGEIMLWNLAAKKAMYTLSAQDE---------VFSLAFSPNRYWLAAATATG-IKVFSLDPQYLVDDLRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRV 312

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
Match: TAF5 (Subunit (90 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification [Source:SGD;Acc:S000000402])

HSP 1 Score: 75.0998 bits (183), Expect = 1.779e-14
Identity = 47/172 (27.33%), Postives = 81/172 (47.09%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            VG S  V    FSPD +YL++G+ D  + +W+  T        + A  ++      V  + FS      A  S D   +++       L+ F   H+  V  V F  +G  + +GS DK+ R+  + +G  ++ F GHT+ V  +   PD + + + S DG + +W + TG+
Sbjct:  522 VGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDT--------HTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCDHIYPLRIF-AGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTAPVISIAVCPDGRWLSTGSEDGIINVWDIGTGK 684

HSP 2 Score: 68.9366 bits (167), Expect = 1.814e-12
Identity = 75/274 (27.37%), Postives = 117/274 (42.70%), Query Frame = 2

Query: 1340 FMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLK-----------------KFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFI-ISNKTNTVAIINIQGQIVRSF---SAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVI-GLVHHPHQNLIATYAEDGLLRLW 2095
            F    K +  L FS D  + AAG QD  IK++ +  G  L                  K    H   V S  FS D   +LSGS DK+VR+  M +   L  +KGH   V DV ++P   +  +AS D T RLWS         R ++G +     +  V   P     F   S+KT  +  ++  G  VR F   +AP       ++  + P G W     ED ++  +++    +L++ +  H K+ I  L +    N++ +   D  +R+W
Sbjct:  462 FQNTNKDMSCLDFSDDCRIAAAGFQDSYIKIWSLD-GSSLNNPNIALNNNDKDEDPTCKTLVGHSGTVYSTSFSPDNKYLLSGSEDKTVRLWSMDTHTALVSYKGHNHPVWDVSFSPLGHYFATASHDQTARLWSCD--HIYPLRIFAGHLND---VDCVSFHPNGCYVFTGSSDKTCRMWDVST-GDSVRLFLGHTAP------VISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQ-MRGHGKNAIYSLSYSKEGNVLISGGADHTVRVW 721

HSP 3 Score: 64.6994 bits (156), Expect = 3.444e-11
Identity = 40/128 (31.25%), Postives = 65/128 (50.78%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTG-KIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMK 1573
             G  + V+   F P+G Y+ TG+ D    +W+  TG  +R  L + A          V+S+    D   L+ GS+DG I V+ I TG+ LK+        + S+ +SK+G  ++SG  D +VR+  +K
Sbjct:  606 AGHLNDVDCVSFHPNGCYVFTGSSDKTCRMWDVSTGDSVRLFLGHTA---------PVISIAVCPDGRWLSTGSEDGIINVWDIGTGKRLKQMRGHGKNAIYSLSYSKEGNVLISGGADHTVRVWDLK 724

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
Match: LST8 (Protein required for the transport of Gap1p; required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat [Source:SGD;Acc:S000004951])

HSP 1 Score: 72.0182 bits (175), Expect = 3.401e-14
Identity = 56/220 (25.45%), Postives = 94/220 (42.73%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIM----------------------------------EKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQT---GQCLKKFEK--AHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSG-KLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSG 1735
            G   +V    F  D +++VT + DG I+VW+  +  I ++ K+ A  N +++                                  + ++ SL  + D  MLAA +  G   V+ +        LK   K  AH   +T +  S D  ++ + S D + R+  +    KL     GH  +V D  ++ D+ ++++ASSD  +RLW L T E  I R Y G
Sbjct:   73 GHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCTHQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSDHYVRLWDLSTRE--IVRQYGG 290

HSP 2 Score: 65.4698 bits (158), Expect = 4.538e-12
Identity = 62/288 (21.53%), Postives = 118/288 (40.97%), Query Frame = 2

Query: 1247 LVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLA-AGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPK---RDGSDFVATI-ISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            LV+   D  I  W  +TG   + +++         +  V  L  + D ++LA AG Q+ ++   R      +  FE  H   VTSV F +D   +++ S D ++++  ++S  + + +K H + VN+V+  P+   +IS   DG +R+W L   + T       L  ++      + +  +      +N      +  +      S   P    R  S ++  I +S   +       D     +++  + KLE T+  H + V           + T + D  +RLW
Sbjct:    5 LVSAGYDHTIRFWEALTGVCSRTIQHS--------DSQVNRLEITNDKKLLATAGHQNVRLYDIRTTNPNPVASFE-GHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRSPSIPRNYK-HNAPVNEVVIHPNQGELISCDRDGNIRIWDLGENQCT-----HQLTPEDDTSLQSLSMASDGSMLAAANTKGNCYVWEMPNHTDASHLKPVTKFRAHSTYITRILLSSDVKHLATCSADHTARVWSIDDDFKLETTLDGHQRWVWDCAFSADSAYLVTASSDHYVRLW 277

HSP 3 Score: 46.2098 bits (108), Expect = 8.299e-6
Identity = 38/170 (22.35%), Postives = 86/170 (50.59%), Query Frame = 2

Query: 1388 SEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKL--LKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGS 1888
            S +L +   D  I+ +   TG C +  + +  + V  ++ + D   +L+ +  ++VR++ +++     +  F+GH   V  V +  DN+ ++++S DGT+++W +++   +I R Y       AP++ V+  P N  + I  ++   + I ++ + Q     + P+ D S
Sbjct:    2 SVILVSAGYDHTIRFWEALTGVCSRTIQHSDSQ-VNRLEITNDK-KLLATAGHQNVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTIKVWDVRS--PSIPRNYK----HNAPVNEVVIHP-NQGELISCDRDGNIRIWDLGENQCTHQLT-PEDDTS 161

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
Match: EDO41499 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4D0])

HSP 1 Score: 431.024 bits (1107), Expect = 3.096e-144
Identity = 193/303 (63.70%), Postives = 251/303 (82.84%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            G  SH E A FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQENFM+M++ VL L FSRDSEMLA+G QDGKIKV+++QTGQCL++FE+AH KGVT V FS+D + +LSGSFD ++R+HG+KSGK LKEF+GHTSFVNDVI+  D  HIISASSDGT+++W++K+ E    ++   G +  E  +++V  +PRN +QF++ NK+NTV I+N+QGQIVRSF++ KRDG DF+  ++SP+GEW YCVGED ++YCF+     KLE+++ +HDKDVIG+VHHPHQNLIA+++EDG L+LWKP
Sbjct:  212 GTKSHPECAAFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQENFMMMDETVLCLTFSRDSEMLASGGQDGKIKVWKLQTGQCLRRFERAHSKGVTCVTFSRDASQLLSGSFDMTIRMHGLKSGKTLKEFRGHTSFVNDVIFTADAHHIISASSDGTIKIWNIKSTECQHTFKPSVGGLSSEITVNSVHLLPRNIEQFVVCNKSNTVVIMNMQGQIVRSFTSGKRDGGDFLCCVLSPRGEWIYCVGEDGVMYCFS-TTTGKLEQSLQVHDKDVIGVVHHPHQNLIASHSEDGQLKLWKP 513

HSP 2 Score: 283.878 bits (725), Expect = 1.545e-87
Identity = 154/208 (74.04%), Postives = 186/208 (89.42%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLSLT 645
            MA+E+ESADVVRL++Q+LKENNL RTLATLQEETGI+LNTVDSVE+F+ EI +GHW+ VL   Q+LKLPD KLIDLYEQ+V+ELIELRELG  R+LLRQTDPMI++KQ Q +R+ HLE +L +SYFD REAYPEG +KE+RR AIA +LA EVSVVPPSRLLALLGQALKWQQ+QG+LPPG++IDVFRGKAAVR++E+EK P+Q+S T
Sbjct:    1 MALEVESADVVRLVQQFLKENNLPRTLATLQEETGITLNTVDSVESFVNEINSGHWDTVLTAIQSLKLPDKKLIDLYEQIVLELIELRELGAARSLLRQTDPMIMLKQQQADRYLHLENMLAKSYFDTREAYPEGGSKERRRAAIAQALAGEVSVVPPSRLLALLGQALKWQQYQGMLPPGTTIDVFRGKAAVRDEEEEKYPSQMSKT 208

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
Match: EDO33297 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SSL6])

HSP 1 Score: 125.176 bits (313), Expect = 2.409e-31
Identity = 83/305 (27.21%), Postives = 146/305 (47.87%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFS +G++L + + D  I++W    GK  K +           +  +  + +S DS  L + S D  +K++   TG+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V  V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED  +Y +NLQ++  +++ +  H   V+    HP +N+IA+ A   D  +++WK
Sbjct:   62 TGHNKAVSSVKFSHNGEWLASSSADKVIKIWGAYDGKFEKTITGH--------KLGISDVAWSTDSRHLVSASDDKTLKIWDFATGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVTAVHFNRDGALIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCVFANFSVTGGKWIVSGSEDHKVYIWNLQSKEVVQK-LDGHSDVVLCCACHPTENIIASGALENDKTIKIWK 351

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
Match: EDO49767 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFR6])

HSP 1 Score: 102.064 bits (253), Expect = 7.144e-24
Identity = 80/302 (26.49%), Postives = 142/302 (47.02%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNT-VAIINIQ-GQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            G+S  +     +PD + ++TG  DG I VW++ TGK             +   K V +L  S  ++ L +G+ D  +K++ + T   +    K H   V+ V  + D   I+S S+DK+V+I  +++   +    GH   V  +    D + ++SAS D TLR+W+L+T     +   S L G    ++ V   P   D+F IS   +T V I +++  + VRS        SD  A  ++P G      G+D  +  ++L++  +L  ++  H + V  +   P    I + +ED   ++W
Sbjct:   11 GRSRTILGIAVTPDTKKIITGGADGSIRVWDYETGK--------ELNKLLDHTKLVYTLALSPHADFLVSGAFDHTVKIWDMDTLSLVHTL-KGHKNWVSGVLVTPDSKRIISSSYDKTVKIWDVETCAFVNSLDGHDGHVRGIAITSDGRRLVSASQDRTLRIWNLET-----FAHVSTLRGHSETVYCVCCSPD--DKFAISGSEDTMVKIWDLESAKEVRSLVGHT---SDIFAVAVTPDGSKVISSGDDTQVKVWSLESGEELA-SLHGHSESVRIVTVSPDGLTIVSGSEDATFKIW 292

HSP 2 Score: 75.485 bits (184), Expect = 6.560e-15
Identity = 42/173 (24.28%), Postives = 82/173 (47.40%), Query Frame = 2

Query: 1172 CIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLW 1690
            C  +N   G   HV     + DG+ LV+ + D  + +WN  T      L+  ++  + +          S D +   +GS+D  +K++ +++ + ++     H   + +V  + DG+ ++S   D  V++  ++SG+ L    GH+  V  V  +PD   I+S S D T ++W
Sbjct:  129 CAFVNSLDGHDGHVRGIAITSDGRRLVSASQDRTLRIWNLETFAHVSTLRGHSETVYCVC--------CSPDDKFAISGSEDTMVKIWDLESAKEVRSL-VGHTSDIFAVAVTPDGSKVISSGDDTQVKVWSLESGEELASLHGHSESVRIVTVSPDGLTIVSGSEDATFKIW 292

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
Match: EDO46560 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RPT3])

HSP 1 Score: 90.1225 bits (222), Expect = 8.320e-20
Identity = 51/163 (31.29%), Postives = 82/163 (50.31%), Query Frame = 2

Query: 1226 FSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT 1714
            FSPD + L TG+  G + + N   GK    L  +         K  +SL +S D   +A G+ DG I +F + T + L   E  H   + S+ FS D   +++ S D  ++++ ++   L     GH+S+V  V + PDN H +S+SSD T+++W   T   T
Sbjct:  111 FSPDSKILATGSHSGKVNLINLELGKKESSLDTRG--------KFTMSLAYSPDGHYIACGAIDGIINIFDLTTNKLLHTLE-GHAMPIRSLTFSPDSQLLITASDDGHIKMYDVQHANLAGTLSGHSSWVLSVAFCPDNTHFVSSSSDKTVKVWDAGTRRCT 264

HSP 2 Score: 81.6481 bits (200), Expect = 5.284e-17
Identity = 55/202 (27.23%), Postives = 98/202 (48.51%), Query Frame = 2

Query: 1238 GQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKG--VTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE--GTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAI 1831
            G    + +LD  + +W+ V+GK  K +     + + +         FS DS++LA GS  GK+ +  ++ G   KK      +G    S+ +S DG  I  G+ D  + I  + + KLL   +GH   +  + ++PD+Q +I+AS DG ++++ ++     GT       L G  + + +V   P NT  F+ S+   TV +
Sbjct:   73 GTLAASSSLDSHVRIWDLVSGKQLKTIDCDPVDTWTVT--------FSPDSKILATGSHSGKVNLINLELG---KKESSLDTRGKFTMSLAYSPDGHYIACGAIDGIINIFDLTTNKLLHTLEGHAMPIRSLTFSPDSQLLITASDDGHIKMYDVQHANLAGT-------LSGHSSWVLSVAFCPDNT-HFVSSSSDKTVKV 255

HSP 3 Score: 79.337 bits (194), Expect = 3.712e-16
Identity = 49/152 (32.24%), Postives = 73/152 (48.03%), Query Frame = 2

Query: 1226 FSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTL 1681
            +SPDG Y+  G +DG I +++  T K+   L+  A          + SL FS DS++L   S DG IK++ +Q    L      H   V SV F  D T+ +S S DK+V++    + +    F  HT  V  V Y      I+S S D ++
Sbjct:  153 YSPDGHYIACGAIDGIINIFDLTTNKLLHTLEGHAM--------PIRSLTFSPDSQLLITASDDGHIKMYDVQHAN-LAGTLSGHSSWVLSVAFCPDNTHFVSSSSDKTVKVWDAGTRRCTHTFYEHTDQVWGVKYNATGSRIVSVSDDRSI 295

HSP 4 Score: 54.6842 bits (130), Expect = 4.698e-8
Identity = 56/237 (23.63%), Postives = 93/237 (39.24%), Query Frame = 2

Query: 1388 SEMLAAGSQDGKIKVFRIQTGQCLKKFE-KAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            +E +  GS D  +K +R    +   KF  + H  GV SV  +  GT   S S D  VRI  + SGK LK           V ++PD++ + + S  G + L +L+ G+            +E+ + T                         +G+   S +              SP G +  C   D ++  F+L   NKL  T+  H   +  L   P   L+ T ++DG ++++
Sbjct:   29 TESILTGSVDDMVKCWRWNDNKLEPKFNFEGHQLGVVSVDVNSTGTLAASSSLDSHVRIWDLVSGKQLKTIDCDPVDTWTVTFSPDSKILATGSHSGKVNLINLELGK------------KESSLDT-------------------------RGKFTMSLA-------------YSPDGHYIACGAIDGIINIFDLTT-NKLLHTLEGHAMPIRSLTFSPDSQLLITASDDGHIKMY 214

HSP 5 Score: 51.2174 bits (121), Expect = 7.102e-7
Identity = 33/123 (26.83%), Postives = 59/123 (47.97%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIH 1564
            G +  +    FSPD Q L+T + DG I++++     +   L   +          VLS+ F  D+    + S D  +KV+   T +C   F + H   V  V+++  G+ I+S S D+S+ ++
Sbjct:  185 GHAMPIRSLTFSPDSQLLITASDDGHIKMYDVQHANLAGTLSGHSS--------WVLSVAFCPDNTHFVSSSSDKTVKVWDAGTRRCTHTFYE-HTDQVWGVKYNATGSRIVSVSDDRSIIVY 298

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
Match: EDO34865 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SN68])

HSP 1 Score: 91.2781 bits (225), Expect = 1.528e-19
Identity = 51/166 (30.72%), Postives = 83/166 (50.00%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLW 1690
            +G    +  A+F+ D  ++VTG++D   ++W+  TGK    L+    E        VL + F    +++A  S DG  +V+   T  CL K E  H   ++ + F+  GT +L+ S DK+ R+    +GK L+  +GHT  +    +  D   II+ S D T RLW
Sbjct:  258 IGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGKCIGTLRGHDDE--------VLDVAFDYTGQLIATASADGTGRVYNALTHHCLSKLE-GHEGEISKITFNAQGTRLLTASSDKTARLWDPNTGKCLQVLEGHTDEIFSCAFNYDGDIIITGSKDNTCRLW 414

HSP 2 Score: 79.337 bits (194), Expect = 9.807e-16
Identity = 46/164 (28.05%), Postives = 81/164 (49.39%), Query Frame = 2

Query: 1217 VAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            +A  +P G  + TG+ D   ++WN  TGK     +  + E        ++ L F+  S ++A GS D   K++ +QTG  +      H   + S  F+  GT +L+GSFD +V +   +SG+ +    GH   +++  +  D   I++ S D T ++W   TG+
Sbjct:  140 IAFNNPYGDKIATGSFDKTCKLWNAETGKCYHTYRGHSAE--------IVCLAFNPQSTVIATGSMDTTAKLWDVQTGAEISTLS-GHSAEIISCAFNSTGTQLLTGSFDHTVSVWDTRSGRRVHTLIGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGK 294

HSP 3 Score: 70.8626 bits (172), Expect = 5.686e-13
Identity = 51/191 (26.70%), Postives = 89/191 (46.60%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTV 1768
            G S+ +    F+P    + TG++D   ++W+  TG     L   + E        ++S  F+     L  GS D  + V+  ++G+ +      H   +++ QF+ D + I++GS DK+ +I    +GK +   +GH   V DV +    Q I +AS+DGT R+++  T         S L G E  I  +
Sbjct:  175 GHSAEIVCLAFNPQSTVIATGSMDTTAKLWDVQTGAEISTLSGHSAE--------IISCAFNSTGTQLLTGSFDHTVSVWDTRSGRRVHTL-IGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGKCIGTLRGHDDEVLDVAFDYTGQLIATASADGTGRVYNALTHH-----CLSKLEGHEGEISKI 351

HSP 4 Score: 68.9366 bits (167), Expect = 2.226e-12
Identity = 44/172 (25.58%), Postives = 80/172 (46.51%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLG-FSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            G S+ +    F+  G  L+TG+ D  + VW+  +G+         + + +I  +  +S   F+ D   +  GS D   K++   TG+C+    + H   V  V F   G  I + S D + R++   +   L + +GH   ++ + +      +++ASSD T RLW   TG+
Sbjct:  217 GHSAEIISCAFNSTGTQLLTGSFDHTVSVWDTRSGR---------RVHTLIGHRGEISNAQFNFDCSFIVTGSMDKTCKIWDAGTGKCIGTL-RGHDDEVLDVAFDYTGQLIATASADGTGRVYNALTHHCLSKLEGHEGEISKITFNAQGTRLLTASSDKTARLWDPNTGK 378

HSP 5 Score: 58.5362 bits (140), Expect = 4.896e-9
Identity = 66/267 (24.72%), Postives = 108/267 (40.45%), Query Frame = 2

Query: 1340 FMIMEKAVLSL---GFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKD-GTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEW----------FYCVGE-DKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            F I+   +L L    F++       GS D   KV+   +G+     E  H   V ++ F+   G  I +GSFDK+ ++   ++GK    ++GH++ +  + + P +  I + S D T +LW ++TG        S L G  A I              IS   N+     + G    + S         V T+I  +GE           F   G  DK    ++     K   T+  HD +V+ +       LIAT + DG  R++
Sbjct:   85 FKILRAHILPLTNVAFNKSGTSFITGSYDRTCKVWDTASGEETLTLE-GHKNVVYAIAFNNPYGDKIATGSFDKTCKLWNAETGKCYHTYRGHSAEIVCLAFNPQSTVIATGSMDTTAKLWDVQTGA-----EISTLSGHSAEI--------------ISCAFNSTGTQLLTGSFDHTVSVWDTRSGRRVHTLIGHRGEISNAQFNFDCSFIVTGSMDKTCKIWD-AGTGKCIGTLRGHDDEVLDVAFDYTGQLIATASADGTGRVY 330

HSP 6 Score: 55.4546 bits (132), Expect = 4.000e-8
Identity = 33/112 (29.46%), Postives = 59/112 (52.68%), Query Frame = 2

Query: 1457 LKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIY-APDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNT 1789
            L K  +AH+  +T+V F+K GT+ ++GS+D++ ++    SG+     +GH + V  + +  P    I + S D T +LW+ +TG     + Y    G  A I  +   P++T
Sbjct:   84 LFKILRAHILPLTNVAFNKSGTSFITGSYDRTCKVWDTASGEETLTLEGHKNVVYAIAFNNPYGDKIATGSFDKTCKLWNAETG-----KCYHTYRGHSAEIVCLAFNPQST 190

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
Match: SMU1 (WD40 repeat-containing protein SMU1 [Source:NCBI gene;Acc:101172828])

HSP 1 Score: 434.876 bits (1117), Expect = 5.647e-146
Identity = 195/313 (62.30%), Postives = 253/313 (80.83%), Query Frame = 2

Query: 1166 NLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE-GTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
             LC  + F  GQ SHVE  +FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL +GFSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT V F KD + +LS SFD+++RIHG+KSGK LKEF+GHTSFVN+  + PD  H+ISASSDGT++LW++KT E  + ++      G +  ++ V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  153 QLCRHIKF--GQKSHVECGRFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMGFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCVSFCKDSSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNEATFTPDGHHVISASSDGTVKLWNVKTTECSSTFKPLGTSAGTDITVNNVLLLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 462

HSP 2 Score: 219.935 bits (559), Expect = 1.165e-63
Identity = 113/206 (54.85%), Postives = 137/206 (66.50%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IE+ESADV+RLI QYLKENNL RTLA+LQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLY                                                    +AYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQ+LKWQQHQGLLPPG +ID+FRGKAAV++ E+E+ PTQL 
Sbjct:    1 MSIEVESADVIRLIMQYLKENNLHRTLASLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLY---------------------------------------------------EQAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLC 155

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
Match: SMU1 (WD40 repeat-containing protein SMU1 [Source:NCBI gene;Acc:101172828])

HSP 1 Score: 434.876 bits (1117), Expect = 2.818e-145
Identity = 195/313 (62.30%), Postives = 253/313 (80.83%), Query Frame = 2

Query: 1166 NLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE-GTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
             LC  + F  GQ SHVE  +FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL +GFSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT V F KD + +LS SFD+++RIHG+KSGK LKEF+GHTSFVN+  + PD  H+ISASSDGT++LW++KT E  + ++      G +  ++ V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  204 QLCRHIKF--GQKSHVECGRFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMGFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCVSFCKDSSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNEATFTPDGHHVISASSDGTVKLWNVKTTECSSTFKPLGTSAGTDITVNNVLLLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

HSP 2 Score: 285.419 bits (729), Expect = 9.960e-88
Identity = 155/206 (75.24%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IE+ESADV+RLI QYLKENNL RTLA+LQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQ+LKWQQHQGLLPPG +ID+FRGKAAV++ E+E+ PTQL 
Sbjct:    1 MSIEVESADVIRLIMQYLKENNLHRTLASLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLC 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
Match: SMU1 (WD40 repeat-containing protein SMU1 [Source:NCBI gene;Acc:101172828])

HSP 1 Score: 434.876 bits (1117), Expect = 2.818e-145
Identity = 195/313 (62.30%), Postives = 253/313 (80.83%), Query Frame = 2

Query: 1166 NLCIILNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE-GTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
             LC  + F  GQ SHVE  +FSPDGQYLVTG++DGFIEVWNF TGKIRKDLKYQAQ+NFM+M+ AVL +GFSRD+EMLA G+QDGKIKV++IQ+GQCL++FE+AH KGVT V F KD + +LS SFD+++RIHG+KSGK LKEF+GHTSFVN+  + PD  H+ISASSDGT++LW++KT E  + ++      G +  ++ V+ +P+N + F++ N++NTV I+N+QGQIVRSFS+ KR+G DFV   +SP+GEW YCVGED +LYCF+     KLERT+ +H+KDVIG+ HHPHQNLI TY+EDGLL+LWKP
Sbjct:  204 QLCRHIKF--GQKSHVECGRFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMGFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCVSFCKDSSQLLSASFDQTIRIHGLKSGKTLKEFRGHTSFVNEATFTPDGHHVISASSDGTVKLWNVKTTECSSTFKPLGTSAGTDITVNNVLLLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCTLSPRGEWIYCVGEDFVLYCFS-TVTGKLERTLTVHEKDVIGIAHHPHQNLIGTYSEDGLLKLWKP 513

HSP 2 Score: 285.419 bits (729), Expect = 9.960e-88
Identity = 155/206 (75.24%), Postives = 183/206 (88.83%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLS 639
            M+IE+ESADV+RLI QYLKENNL RTLA+LQEET +SLNTVDS+E+F+A+I +GHW+ VLQ  Q+LKLPD  LIDLYEQVV+ELIELRELG  R+LLRQTDPMI++KQ QPER+ HLE LL RSYFDPREAYP+G +KEKRR AIA +LA EVSVVPPSRL+ALLGQ+LKWQQHQGLLPPG +ID+FRGKAAV++ E+E+ PTQL 
Sbjct:    1 MSIEVESADVIRLIMQYLKENNLHRTLASLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQSLKWQQHQGLLPPGMTIDLFRGKAAVKDVEEERFPTQLC 206

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
Match: smu1b (WD40 repeat-containing protein SMU1 [Source:NCBI gene;Acc:101168770])

HSP 1 Score: 375.555 bits (963), Expect = 2.376e-122
Identity = 167/303 (55.12%), Postives = 235/303 (77.56%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEA-PIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            G+ SHV  A+FSPDG+YL+TG++DGFIEVWNF TGKI KDLKYQAQ++FM+M+ AVL + FS+D++MLA G+Q+GKIKV++IQ+G CL++FE AH KGVT + FSKD + ILSGSFD+++RIH ++SGK LKE  GH+SFVND  +  D  HIISASSDG++++W++K+ E       S L    + P++ V+P+P+N   F++ N+++TVA++++ GQ V++F+  +    +FV    SP+GEW YCVGED +LYCF   +  +LE+T+ +H+KDVIG+ HHPH+NL+ATY  DGLLRLWKP
Sbjct:  212 GRHSHVRCARFSPDGRYLITGSVDGFIEVWNFNTGKINKDLKYQAQDSFMMMDDAVLCMCFSQDTDMLATGAQNGKIKVWKIQSGLCLRRFEHAHNKGVTCLSFSKDNSQILSGSFDQTLRIHELRSGKTLKELNGHSSFVNDAAFIRDGSHIISASSDGSVKIWNIKSCE-----CISNLSAAPSIPVNNVIPLPQNPQHFVVCNQSSTVAVMSMLGQTVKTFTPDRSQTVNFVCCTTSPRGEWIYCVGEDCVLYCFKY-STGRLEKTLTVHEKDVIGVAHHPHENLLATYGGDGLLRLWKP 508

HSP 2 Score: 196.823 bits (499), Expect = 9.545e-55
Identity = 122/207 (58.94%), Postives = 153/207 (73.91%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEK--CPTQL 636
            MA+E+E  DV+RLI QYLKENNL RTL+TLQEET +SLNTV+S E+F+A+I  GHW+ VL   ++LKLPD  L DLYEQVV+ELIE+RE+G  R LLRQTDPMI++KQ QPE+++ LE LL + YFDPREAYP+G +KEKRR+A+A +L  EV VVPPSRL+ LL Q     + Q   P   S D+    +  +EQ  EK   PTQL
Sbjct:    1 MAVEMEPTDVIRLIMQYLKENNLYRTLSTLQEETTVSLNTVESFESFIADINRGHWDSVLLAIESLKLPDNILTDLYEQVVMELIEMREVGAARALLRQTDPMIMLKQTQPEKYSRLEKLLTQPYFDPREAYPKGSSKEKRRRALAEALMREVCVVPPSRLIGLLEQVTCMTRQQN--PGCISADMIVDSSGKKEQHVEKDSFPTQL 205

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
Match: wdr5 (WD repeat domain 5 [Source:NCBI gene;Acc:101166483])

HSP 1 Score: 136.346 bits (342), Expect = 7.537e-35
Identity = 85/305 (27.87%), Postives = 149/305 (48.85%), Query Frame = 2

Query: 1193 VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINI-QGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYA--EDGLLRLWK 2098
             G +  V   KFSP G++L + + D  I++W    GK  K +           +  +  + +S DS +L + S D  +K++ + +G+CLK   K H   V    F+     I+SGSFD+SVRI  +K+GK LK    H+  V+ V +  D   I+S+S DG  R+W   +G+         L+  + P  + +    N    + +   NT+ + +  +G+ +++++  K +     A      G+W     ED ++Y +NLQ +  +++ +  H   VI    HP +N+IA+ A   D  ++LWK
Sbjct:   42 AGHTKAVSSVKFSPSGEWLASSSADKLIKIWGAYDGKFEKTISGH--------KLGISDVAWSSDSNLLVSASDDKTLKIWDVNSGKCLKTL-KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQ-----CLKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNMVYIWNLQTKEIVQK-LQGHTDVVISTACHPTENIIASAALENDKTIKLWK 331

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST
Match: SMESG000005039.1 (SMESG000005039.1)

HSP 1 Score: 634.795 bits (1636), Expect = 0.000e+0
Identity = 304/307 (99.02%), Postives = 304/307 (99.02%), Query Frame = 2

Query: 1181 LNF*VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 2101
            L   VGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP
Sbjct:  207 LTIKVGQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWKP 513

HSP 2 Score: 371.703 bits (953), Expect = 7.394e-121
Identity = 208/208 (100.00%), Postives = 208/208 (100.00%), Query Frame = 1

Query:   22 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYXXXXXXXXXXXXXXXXXXXXXXXDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLSLT 645
            MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYEQVVIELIELRELGGGRTLLRQTDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLSLT
Sbjct:    1 MAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDSVENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYEQVVIELIELRELGGGRTLLRQTDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQAIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAVREQEDEKCPTQLSLT 208

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST
Match: SMESG000076568.1 (SMESG000076568.1)

HSP 1 Score: 87.8113 bits (216), Expect = 1.139e-18
Identity = 55/174 (31.61%), Postives = 83/174 (47.70%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKF-EKAHVKGVTSVQFSKDGTN--ILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            G +  V     S DGQ+ ++G+ DG + +W+  +G        Q    F+   K VLS+ FS D+  + +GS+DG IK++    G C     E  H   V+ V+FS    N  I+S  +DK V++  + + KL     GH  ++N V  +PD     S   DG   LW L  G 
Sbjct:   61 GHNGFVSDVVMSSDGQFALSGSWDGTLRLWDLTSG--------QTTRRFVGHTKDVLSVAFSADNRQIVSGSRDGTIKLWNT-LGVCKYTIQEDGHTDWVSCVRFSPTSENPSIVSCGWDKVVKVWNLSNCKLRTNHFGHNGYLNTVAVSPDGSLCASGGKDGQAMLWDLSEGR 225

HSP 2 Score: 64.6994 bits (156), Expect = 5.521e-11
Identity = 35/103 (33.98%), Postives = 59/103 (57.28%), Query Frame = 2

Query: 1397 LAAGSQDGKIKVFRIQTGQCLKKFEKAHVKG----VTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWS 1693
            L + S+D  + ++ +   +    + K  +KG    V+ V  S DG   LSGS+D ++R+  + SG+  + F GHT  V  V ++ DN+ I+S S DGT++LW+
Sbjct:   31 LISASRDKSLIIWELNRDENSFGYAKRALKGHNGFVSDVVMSSDGQFALSGSWDGTLRLWDLTSGQTTRRFVGHTKDVLSVAFSADNRQIVSGSRDGTIKLWN 133

HSP 3 Score: 62.003 bits (149), Expect = 4.279e-10
Identity = 60/202 (29.70%), Postives = 96/202 (47.52%), Query Frame = 2

Query: 1526 ILSGSFDKSVRIHGMKS-----GKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHT--VMPVPRNTD--QFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATI-ISPKGE--WFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            ++S S DKS+ I  +       G   +  KGH  FV+DV+ + D Q  +S S DGTLRLW L +G+ T  R + G        HT  V+ V  + D  Q +  ++  T+ + N  G  V  ++  +   +D+V+ +  SP  E       G DK++  +NL +  KL      H+  +  +   P  +L A+  +DG   LW
Sbjct:   31 LISASRDKSLIIWELNRDENSFGYAKRALKGHNGFVSDVVMSSDGQFALSGSWDGTLRLWDLTSGQTT--RRFVG--------HTKDVLSVAFSADNRQIVSGSRDGTIKLWNTLG--VCKYTIQEDGHTDWVSCVRFSPTSENPSIVSCGWDKVVKVWNL-SNCKLRTNHFGHNGYLNTVAVSPDGSLCASGGKDGQAMLW 219

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST
Match: SMESG000023395.1 (SMESG000023395.1)

HSP 1 Score: 86.6557 bits (213), Expect = 1.346e-18
Identity = 50/149 (33.56%), Postives = 81/149 (54.36%), Query Frame = 2

Query: 1226 FSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSD 1672
            FSPD +++ TG  +G I +    +GKI + +  +         K  LS+ +S     LAAG+ +G I +  IQTGQ   K +  H   V  + FS DG  ++S S D  ++++ + SG ++    GH+++V  V +  DN+HI+S SSD
Sbjct:  114 FSPDSRFIATGCQEGDINLIGVDSGKIERTISLKG--------KFCLSIAYSPLGTHLAAGALNGMINICDIQTGQL--KSQDGHAMPVRGLAFSHDGQRLVSASDDGQIKVYDVTSGSVVTTLTGHSNWVLGVDFCADNRHIVSCSSD 252

HSP 2 Score: 61.6178 bits (148), Expect = 4.310e-10
Identity = 34/156 (21.79%), Postives = 78/156 (50.00%), Query Frame = 2

Query: 1241 QYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGE 1708
            +Y++TG+LD  ++VW +   ++      +           VLS+  ++   + A+ S D +I ++ +++GQ ++ F+ A      ++ FS D   I +G  +  + + G+ SGK+ +       F   + Y+P   H+ + + +G + +  ++TG+
Sbjct:   32 EYILTGSLDNNVKVWKWNVDRLEYIRTCEGHR------LGVLSVDINKSGTLAASSSLDAQIIIWDLESGQQMRSFDGAANLDAWTLMFSPDSRFIATGCQEGDINLIGVDSGKIERTISLKGKFCLSIAYSPLGTHLAAGALNGMINICDIQTGQ 181

HSP 3 Score: 60.8474 bits (146), Expect = 7.690e-10
Identity = 39/156 (25.00%), Postives = 80/156 (51.28%), Query Frame = 2

Query: 1238 GQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTG 1705
            G    + +LD  I +W+  +G+  +     A  +         +L FS DS  +A G Q+G I +  + +G+ +++      K   S+ +S  GT++ +G+ +  + I  +++G+L K   GH   V  + ++ D Q ++SAS DG ++++ + +G
Sbjct:   75 GTLAASSSLDAQIIIWDLESGQQMRSFDGAANLD-------AWTLMFSPDSRFIATGCQEGDINLIGVDSGK-IERTISLKGKFCLSIAYSPLGTHLAAGALNGMINICDIQTGQL-KSQDGHAMPVRGLAFSHDGQRLVSASDDGQIKVYDVTSG 221

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST
Match: SMESG000024482.1 (SMESG000024482.1)

HSP 1 Score: 81.2629 bits (199), Expect = 7.451e-16
Identity = 56/183 (30.60%), Postives = 89/183 (48.63%), Query Frame = 2

Query: 1211 VEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPI 1759
            V     S D   +VTG+ D  I+VW       R+   Y   E+    +  V  + FS D +++A+ S D  IK++     +C+  F++ H   V S+ F  +G+ I SG  D  V I  ++  KLL+ +  HTS VN V + P    +IS+S D +++++ L  G     R    + G E PI
Sbjct:  101 VRSVDISCDNLEMVTGSDDKTIKVWKM----HRQKFSYSLNEH----KNWVRCVRFSSDGQLIASSSDDKTIKLWDRHNQECIHTFQE-HGGFVPSLAFHPNGSYIASGGTDSHVNIWDIRMNKLLQHYTSHTSPVNAVSFHPSGNFLISSSDDSSMKIYDLLEG-----RLLYTVQGHEGPI 269

HSP 2 Score: 78.1814 bits (191), Expect = 7.743e-15
Identity = 75/306 (24.51%), Postives = 139/306 (45.42%), Query Frame = 2

Query: 1196 GQSSHVEVAKFSPDGQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQE-NFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQ-TGQCLKKFEKAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGT-IWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNT-VAIINIQ-GQIVRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLWK 2098
            G    V    F+P+   L +G +D  + +WNF         K Q +   F+  E A+LS+ FS   +++A+ S+D  ++++     G+ L    +AH   V SV  S D   +++GS DK++++  M   K       H ++V  V ++ D Q I S+S D T++LW     E    ++ + G V    P     P       +I S  T++ V I +I+  ++++ +++     S   A    P G +     +D  +  ++L  E +L  T+  H+  ++G        + A+   D  + LW+
Sbjct:   12 GHKDKVTCVDFNPNSSQLASGGIDSCLMIWNF---------KPQTRAYRFVGHEDAILSVKFSPTGQLVASASRDKTVRLWVPSIKGESL--VFRAHTATVRSVDISCDNLEMVTGSDDKTIKVWKMHRQKFSYSLNEHKNWVRCVRFSSDGQLIASSSDDKTIKLWDRHNQECIHTFQEHGGFV----PSLAFHP----NGSYIASGGTDSHVNIWDIRMNKLLQHYTS---HTSPVNAVSFHPSGNFLISSSDDSSMKIYDL-LEGRLLYTVQGHEGPILGTAFSHCGEMFASGGADHQVFLWQ 294

HSP 3 Score: 56.6102 bits (135), Expect = 4.397e-8
Identity = 54/213 (25.35%), Postives = 92/213 (43.19%), Query Frame = 2

Query: 1472 KAHVKGVTSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLW--SLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTD--QFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATI-ISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRLW 2095
            K H   VT V F+ + + + SG  D  + I   K       F GH   +  V ++P  Q + SAS D T+RLW  S+K GE  ++RA++          TV  V  + D  + +  +   T+ +  +  Q    FS    +  ++V  +  S  G+      +DK +  ++   +  +  T   H   V  L  HP+ + IA+   D  + +W
Sbjct:   11 KGHKDKVTCVDFNPNSSQLASGGIDSCLMIWNFKPQTRAYRFVGHEDAILSVKFSPTGQLVASASRDKTVRLWVPSIK-GESLVFRAHTA---------TVRSVDISCDNLEMVTGSDDKTIKVWKMHRQ---KFSYSLNEHKNWVRCVRFSSDGQLIASSSDDKTIKLWDRHNQECIH-TFQEHGGFVPSLAFHPNGSYIASGGTDSHVNIW 209

[Close]

BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST
Match: SMESG000079131.1 (SMESG000079131.1)

HSP 1 Score: 80.1073 bits (196), Expect = 2.147e-15
Identity = 83/341 (24.34%), Postives = 141/341 (41.35%), Query Frame = 2

Query: 1127 INFREEPWALLHKNLCIILNF*VGQSSH-----VEVAKFSPD-GQYLVTGTLDGFIEVWNFVTGKIRKDLKYQAQENFMIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGVTSVQFSKDGTNI-LSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPDNQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTDQFIISNKTNTVAIINIQGQI----------VRSFSAPKRDGSDFVATIISPKGEWFYCVGEDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQ-NLIATYAEDGLLRLW 2095
            +NF+ E    L    C +    V Q S+     V V +  P  G  ++TG +D +I +W  V G+ R         +++   +A+  L F+ D     + S D  IK++  +TGQCL +F   H+  V       D  ++ L+G  +K +  + ++SG+ ++ ++ H   VN + +   N+  +S S D +LR+W     E  I   Y  L          + V RN+   +  +  N +   N+              V + SA + D S  +  +IS  GE    V + K   C             P H K     V  P + + + T   DG ++LW
Sbjct:  240 VNFKSE----LPPGKCFVPKKMVYQWSNAHRQGVSVVRLFPSTGHLMLTGGMDKYIRLWE-VYGERR------LLRSYLGHREAIKDLAFNNDGSQFLSSSYDKYIKLWVTETGQCLSQFTNKHIANVIKFNPDIDKQHLFLAGCQNKKILCYDVRSGETVQLYERHLGAVNSITFFDGNKRFVSTSDDRSLRMW-----EWDIPVDYRVLADPSMHSMPSVNVSRNSKWLVCQSLDNQIVTYNLDAGFKKTKKVFRNQVAAGSACQIDFSPDMKYLISGDGEGKIFVWDFKTTKCI---------EQWPGHTKAATAAVWLPQETSKVITAGWDGHIKLW 555

The following BLAST results are available for this feature:

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Celegans
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SMU1	7.314e-144	63.04	SMU1 DNA replication regulator and spliceosomal fa...	[more]
WDR5	5.627e-35	28.20	WD repeat domain 5 [Source:HGNC Symbol;Acc:HGNC:12...	[more]
WDR5B	3.966e-33	28.62	WD repeat domain 5B [Source:HGNC Symbol;Acc:HGNC:1...	[more]
KATNB1	7.130e-22	29.81	katanin regulatory subunit B1 [Source:HGNC Symbol;...	[more]
RACK1	2.402e-19	31.61	receptor for activated C kinase 1 [Source:HGNC Sym...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
smu-1	3.729e-114	54.18	Smu-1 suppressor of mec-8 and unc-52 protein [Sou...	[more]
smu-1	3.729e-114	54.18	Smu-1 suppressor of mec-8 and unc-52 protein [Sou...	[more]
wdr-5.2	3.638e-32	29.15	WD repeat-containing protein wdr-5.2 [Source:UniP...	[more]
wdr-5.1	6.273e-27	26.16	WD repeat-containing protein wdr-5.1 [Source:UniP...	[more]
wdr-5.1	6.273e-27	26.16	WD repeat-containing protein wdr-5.1 [Source:UniP...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Smu1	4.206e-144	62.91	gene:FBgn0038666 transcript:FBtr0083721	[more]
Smu1	4.206e-144	62.91	gene:FBgn0038666 transcript:FBtr0304690	[more]
Smu1	4.206e-144	62.91	gene:FBgn0038666 transcript:FBtr0304689	[more]
wds	1.873e-34	27.87	gene:FBgn0040066 transcript:FBtr0308566	[more]
wds	1.873e-34	27.87	gene:FBgn0040066 transcript:FBtr0070438	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
smu1a	2.333e-144	63.37	SMU1 DNA replication regulator and spliceosomal fa...	[more]
smu1b	1.185e-134	59.74	SMU1 DNA replication regulator and spliceosomal fa...	[more]
smu1b	4.842e-134	59.74	SMU1 DNA replication regulator and spliceosomal fa...	[more]
smu1b	6.533e-132	59.74	SMU1 DNA replication regulator and spliceosomal fa...	[more]
wdr5	8.127e-35	27.87	WD repeat domain 5 [Source:ZFIN;Acc:ZDB-GENE-04042...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ppp6c	2.487e-143	62.38	protein phosphatase 6, catalytic subunit [Source:X...	[more]
ppp6c	8.181e-143	62.38	protein phosphatase 6, catalytic subunit [Source:X...	[more]
ppp6c	1.118e-142	62.38	protein phosphatase 6, catalytic subunit [Source:X...	[more]
ppp4r1l	1.021e-35	27.64	protein phosphatase 4 regulatory subunit 1 like (p...	[more]
ppp4r1l	1.450e-35	28.20	protein phosphatase 4 regulatory subunit 1 like (p...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Smu1	5.021e-144	63.04	smu-1 suppressor of mec-8 and unc-52 homolog (C. e...	[more]
Wdr5	3.863e-35	28.20	WD repeat domain 5 [Source:MGI Symbol;Acc:MGI:2155...	[more]
Wdr5b	1.193e-31	26.97	WD repeat domain 5B [Source:MGI Symbol;Acc:MGI:191...	[more]
Wdr5	1.770e-25	28.79	WD repeat domain 5 [Source:MGI Symbol;Acc:MGI:2155...	[more]
Katnb1	5.480e-22	29.81	katanin p80 (WD40-containing) subunit B 1 [Source:...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q7ZVA0\|SMU1_DANRE	8.830e-144	63.37	WD40 repeat-containing protein SMU1 OS=Danio rerio...	[more]
sp\|Q3UKJ7\|SMU1_MOUSE	3.512e-143	63.04	WD40 repeat-containing protein SMU1 OS=Mus musculu...	[more]
sp\|Q2TAY7\|SMU1_HUMAN	3.512e-143	63.04	WD40 repeat-containing protein SMU1 OS=Homo sapien...	[more]
sp\|Q76B40\|SMU1_CRIGR	3.512e-143	63.04	WD40 repeat-containing protein SMU1 OS=Cricetulus ...	[more]
sp\|Q2TBS9\|SMU1_BOVIN	3.512e-143	63.04	WD40 repeat-containing protein SMU1 OS=Bos taurus ...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A183AXA3	1.234e-158	69.08	WD_REPEATS_REGION domain-containing protein OS=Ech...	[more]
A0A504Y7J8	9.566e-154	68.09	WD40 repeat-containing protein SMU1 OS=Fasciola gi...	[more]
A0A4E0RFF1	3.042e-153	68.09	WD40 repeat-containing protein SMU1 OS=Fasciola he...	[more]
A0A183TJ06	8.172e-153	66.12	Uncharacterized protein OS=Schistocephalus solidus...	[more]
A0A3P7CY36	8.626e-153	66.12	Uncharacterized protein OS=Schistocephalus solidus...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
smu1a	9.482e-135	60.40	SMU1 DNA replication regulator and spliceosomal fa...	[more]
smu1b	1.653e-125	56.91	WD40 repeat-containing protein SMU1-like [Source:N...	[more]
wdr5	6.315e-35	27.87	WD repeat domain 5 [Source:NCBI gene;Acc:103033424...	[more]
ENSAMXT00000007963.2	2.560e-34	27.54	WD repeat-containing protein 5-like [Source:NCBI g...	[more]
wdr5	9.828e-29	27.21	WD repeat domain 5 [Source:NCBI gene;Acc:103033424...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000002506.1	3.316e-19	31.61	pep scaffold:Pmarinus_7.0:GL479076:26529:32136:-1 ...	[more]
pafah1b1b	2.305e-18	25.00	platelet-activating factor acetylhydrolase 1b, reg...	[more]
wdr61	1.842e-17	33.33	WD repeat domain 61 [Source:NCBI gene;Acc:393827]	[more]
POC1A	2.574e-17	23.68	POC1 centriolar protein A [Source:HGNC Symbol;Acc:...	[more]
ENSPMAT00000008862.1	6.258e-16	25.89	pep scaffold:Pmarinus_7.0:GL476579:86637:114999:1 ...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 5


Match Name	E-value	Identity	Description
PFS2	3.839e-18	23.92	Integral subunit of the pre-mRNA CPF complex; the ...	[more]
TUP1	3.337e-17	30.99	General repressor of transcription; forms complex ...	[more]
ASC1	1.855e-15	28.14	G-protein beta subunit and guanine dissociation in...	[more]
TAF5	1.779e-14	27.33	Subunit (90 kDa) of TFIID and SAGA complexes; invo...	[more]
LST8	3.401e-14	25.45	Protein required for the transport of Gap1p; requi...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO41499	3.096e-144	63.70	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO33297	2.409e-31	27.21	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO49767	7.144e-24	26.49	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO46560	8.320e-20	31.29	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO34865	1.528e-19	30.72	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
SMU1	5.647e-146	62.30	WD40 repeat-containing protein SMU1 [Source:NCBI g...	[more]
SMU1	2.818e-145	62.30	WD40 repeat-containing protein SMU1 [Source:NCBI g...	[more]
SMU1	2.818e-145	62.30	WD40 repeat-containing protein SMU1 [Source:NCBI g...	[more]
smu1b	2.376e-122	55.12	WD40 repeat-containing protein SMU1 [Source:NCBI g...	[more]
wdr5	7.537e-35	27.87	WD repeat domain 5 [Source:NCBI gene;Acc:101166483...	[more]

BLAST of WD40 repeat-containing protein SMU1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000005039.1	7.394e-121	99.02	SMESG000005039.1	[more]
SMESG000076568.1	1.139e-18	31.61	SMESG000076568.1	[more]
SMESG000023395.1	1.346e-18	33.56	SMESG000023395.1	[more]
SMESG000024482.1	7.451e-16	30.60	SMESG000024482.1	[more]
SMESG000079131.1	2.147e-15	24.34	SMESG000079131.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence
protein sequence

transcript sequence

>SMED30035299 ID=SMED30035299|Name=WD40 repeat-containing protein SMU1|organism=Schmidtea mediterranea sexual|type=transcript|length=2139bp
CTTAATTGGTTTAATTTTAAAATGGCAATTGAAATTGAATCTGCAGATGT
TGTAAGATTAATTGAACAGTATCTCAAGGAAAATAATTTAATGAGAACTC
TAGCAACTCTTCAAGAAGAAACTGGTATTTCATTAAATACAGTGGACTCC
GTTGAAAATTTCATGGCTGAAATTACTAACGGACATTGGGAGGTTGTATT
GCAAGTCACTCAAAATCTTAAATTACCAGATGCAAAATTAATAGATTTAT
ATGAGCAAGTTGTCATTGAATTAATTGAGTTACGAGAGTTAGGTGGCGGT
AGAACGTTGTTAAGGCAAACAGATCCCATGATTCTTATGAAACAAAATCA
ACCTGAAAGACATGCTCATTTAGAAGCATTGTTAATGAGATCATATTTTG
ATCCTAGGGAAGCATATCCTGAAGGTCAAACGAAAGAAAAGCGTCGCCAA
GCTATTGCTCATTCATTAGCATCAGAAGTTAGTGTTGTTCCACCTTCTAG
ATTGCTAGCATTGCTTGGACAAGCGCTTAAATGGCAACAGCACCAAGGAT
TATTGCCACCTGGTTCATCAATAGATGTGTTCAGGGGTAAGGCAGCTGTA
AGAGAACAGGAAGATGAAAAATGTCCCACTCAACTCAGTTTAACAATTAA
GGTAATAATTAAAAAAATATTTAAATATAAAAAAGTATAATTTAATTTAA
GTAATTAATTAAATAATCAACACTAAATTTTTAGTGTTAATTTCTATTTT
AATTGCATTTTATTTTTTGTATGTTATACTAATTTTTTTATAATTATTAT
AACATTTTCATTAATTTTCATAAGATTTTACAGTATAATTTTTATAATGA
CTGCATAAATTTTGACAATTTTTTGTAAAGGAGTTGCTATTGCGGTTTTC
TGAATATTTGCTGTTTCTTTTTGAATTTGGAAATATGGTTTTTCTAAATC
AATAGTAGAAAATTTACACTTATTTCTTGTCGTATTGATTATATTTTCGG
TTTTGTATCTGGGATAGTTTTACAGTTGACCTCATGATTAACTACATATT
CTAAACTCTACTTTTTCCCATTATCAAAGATATGTAGCATTTTGATGGTC
TACGCTTCCAGGTTTGAAGTCCAAATATAAACTTTAGGGAGGAACCTTGG
GCCTTACTGCACAAAAATCTTTGTATTATATTGAATTTTTAGGTTGGCCA
GTCTTCTCACGTTGAAGTTGCGAAATTCAGTCCGGACGGACAATATCTTG
TCACAGGAACACTCGATGGTTTCATTGAAGTGTGGAATTTTGTTACTGGT
AAAATCCGCAAGGATTTGAAATACCAAGCCCAGGAAAACTTCATGATAAT
GGAGAAAGCTGTACTCAGCTTGGGATTTAGTCGAGATTCGGAAATGTTAG
CAGCCGGCTCCCAGGATGGAAAAATTAAAGTGTTCCGAATTCAAACTGGC
CAATGTTTGAAAAAATTTGAAAAAGCCCACGTAAAAGGAGTTACAAGTGT
TCAATTTTCCAAAGACGGGACGAATATTCTATCTGGCAGCTTTGACAAAT
CGGTTCGAATTCACGGCATGAAATCGGGAAAACTACTGAAAGAGTTTAAA
GGCCACACATCGTTTGTAAATGACGTGATTTACGCTCCGGACAATCAGCA
CATCATTAGTGCAAGCTCAGACGGAACTCTGAGACTTTGGTCTTTGAAAA
CCGGGGAAGGGACAATTTGGCGCGCCTATTCTGGTTTAGTGGGACAAGAA
GCCCCAATTCATACCGTAATGCCAGTTCCGAGGAACACCGACCAATTCAT
TATCAGTAACAAGACGAACACTGTAGCAATAATCAATATTCAAGGCCAAA
TCGTTCGGAGTTTCTCGGCTCCCAAGCGAGATGGCTCGGATTTCGTTGCG
ACTATTATCAGTCCGAAAGGAGAATGGTTCTATTGTGTAGGGGAAGATAA
ACTTCTTTATTGCTTCAACCTGCAGGCGGAAAATAAACTTGAACGAACCA
TTCCTATTCACGATAAAGATGTCATTGGACTCGTTCATCACCCACATCAG
AATCTGATTGCAACATATGCAGAGGATGGCTTGCTAAGGCTATGGAAGCC
ATAATTACTGTGTTTTAGTGAAATAAATTCTCTGTTTCT

protein sequence of SMED30035299-orf-1

>SMED30035299-orf-1 ID=SMED30035299-orf-1|Name=SMED30035299-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=230bp
LNWFNFKMAIEIESADVVRLIEQYLKENNLMRTLATLQEETGISLNTVDS
VENFMAEITNGHWEVVLQVTQNLKLPDAKLIDLYEQVVIELIELRELGGG
RTLLRQTDPMILMKQNQPERHAHLEALLMRSYFDPREAYPEGQTKEKRRQ
AIAHSLASEVSVVPPSRLLALLGQALKWQQHQGLLPPGSSIDVFRGKAAV
REQEDEKCPTQLSLTIKVIIKKIFKYKKV*

protein sequence of SMED30035299-orf-2

>SMED30035299-orf-2 ID=SMED30035299-orf-2|Name=SMED30035299-orf-2|organism=Schmidtea mediterranea sexual|type=polypeptide|length=254bp
MIMEKAVLSLGFSRDSEMLAAGSQDGKIKVFRIQTGQCLKKFEKAHVKGV
TSVQFSKDGTNILSGSFDKSVRIHGMKSGKLLKEFKGHTSFVNDVIYAPD
NQHIISASSDGTLRLWSLKTGEGTIWRAYSGLVGQEAPIHTVMPVPRNTD
QFIISNKTNTVAIINIQGQIVRSFSAPKRDGSDFVATIISPKGEWFYCVG
EDKLLYCFNLQAENKLERTIPIHDKDVIGLVHHPHQNLIATYAEDGLLRL
WKP*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0000381	regulation of alternative mRNA splicing, via spliceosome
GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0008380	RNA splicing
GO:0008150	biological_process

Vocabulary: **cellular component**
Term	Definition
GO:0005681	spliceosomal complex
GO:0016607	nuclear speck
GO:0071005	U2-type precatalytic spliceosome
GO:0005634	nucleus
GO:0005737	cytoplasm

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0002109	X1 cell
PLANA:0002111	X2 cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036322	WD40_repeat_dom_sf
IPR020472	G-protein_beta_WD-40_rep
IPR001680	WD40_repeat
IPR015943	WD40/YVTN_repeat-like_dom_sf
IPR019775	WD40_repeat_CS
IPR017986	WD40_repeat_dom
IPR006594	LisH
IPR006595	CTLH_C

Vocabulary: **molecular function**
Term	Definition
GO:0005515	protein binding
GO:0003674	molecular_function

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001680	WD40 repeat	SMART	SM00320	WD40_4	coord: 78..117 e-value: 1.1E-10 score: 51.5 coord: 1..32 e-value: 12.0 score: 10.3 coord: 167..209 e-value: 22.0 score: 8.5 coord: 213..252 e-value: 0.012 score: 24.8 coord: 35..75 e-value: 3.8E-7 score: 39.8
IPR001680	WD40 repeat	PFAM	PF00400	WD40	coord: 217..252 e-value: 0.27 score: 12.2 coord: 7..31 e-value: 0.031 score: 15.2 coord: 79..117 e-value: 2.5E-8 score: 34.4 coord: 36..73 e-value: 6.2E-7 score: 30.0
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 85..122 score: 15.922
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 220..253 score: 10.074
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 1..41 score: 9.74
IPR001680	WD40 repeat	PROSITE	PS50082	WD_REPEATS_2	coord: 43..84 score: 10.943
IPR015943	WD40/YVTN repeat-like-containing domain superfamily	GENE3D	G3DSA:2.130.10.10		coord: 3..253 e-value: 5.3E-55 score: 188.4
None	No IPR available	PANTHER	PTHR22848	WD40 REPEAT PROTEIN	coord: 1..253
None	No IPR available	PANTHER	PTHR22848:SF2	WD40 REPEAT-CONTAINING PROTEIN SMU1	coord: 1..253
None	No IPR available	CDD	cd00200	WD40	coord: 4..252 e-value: 1.3581E-43 score: 147.096
IPR017986	WD40-repeat-containing domain	PROSITE	PS50294	WD_REPEATS_REGION	coord: 1..253 score: 31.481
IPR036322	WD40-repeat-containing domain superfamily	SUPERFAMILY	SSF50978	WD40 repeat-like	coord: 6..252