Prothrombin
Overview
Neoblast Clusters
Zeng et. al., 2018
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny AppEmbryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035288 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Prothrombin vs. Ensembl Human
Match: MST1 (macrophage stimulating 1 [Source:HGNC Symbol;Acc:HGNC:7380]) HSP 1 Score: 77.411 bits (189), Expect = 2.152e-16 Identity = 48/145 (33.10%), Postives = 70/145 (48.28%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN-WCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQ--LVGNKCRNPDMS 517 I +G Y G + G PC +W ++ N D Y T + +E N+CRNP P GPWC + + ++ C I+SC + WC G EY G ++ T++G+ C+ W +Q + P K L N CRNPD S Sbjct: 125 IMNNGVGYRGTMATTVGGLPCQAWSHKFPN-----DHKYTPTLRNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWC----NGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGS 260 HSP 2 Score: 63.929 bits (154), Expect = 8.678e-12 Identity = 46/159 (28.93%), Postives = 70/159 (44.03%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I++C+ + +G EY G + +++GR C W ++ ++ + + D ++ NYCRNP PWC + +E E C + C E ++ KG Y G N T G C+ W Q + PEK L N CRNPD S Sbjct: 197 IKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQG--LDDNYCRNPDG-SERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGS 352 HSP 3 Score: 48.9062 bits (115), Expect = 1.219e-6 Identity = 39/139 (28.06%), Postives = 57/139 (41.01%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCH-IRSCIKE-RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN-SF-PEKSFQLVGNKCRNPD 511 G Y G N + G PC W + ++ Y + N+CRNP PWC + C+ IR C + R G +Y G ++ T+ G C+ W ++ + +F E QL N CRNPD Sbjct: 302 GEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKY--ACKDLRENFCRNPDG-SEAPWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPD 437
BLAST of Prothrombin vs. Ensembl Human
Match: HGF (hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893]) HSP 1 Score: 71.633 bits (174), Expect = 7.293e-15 Identity = 48/146 (32.88%), Postives = 66/146 (45.21%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 I NC I GR Y G +++K+G C W +E S Y ++ NYCRNP GPWC + +E C I C + T G Y G ++ T++GKIC+ W Q+ + PE+ N CRNPD Sbjct: 125 IRNC-IIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPD 264
BLAST of Prothrombin vs. Ensembl Human
Match: PLG (plasminogen [Source:HGNC Symbol;Acc:HGNC:9071]) HSP 1 Score: 72.7886 bits (177), Expect = 7.384e-15 Identity = 51/166 (30.72%), Postives = 75/166 (45.18%), Query Frame = 2 Query: 20 IFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 I + +L + LS CK T +G+ Y G + +KNG C W + + + + +E NYCRNP N P GPWC + +++C I C +E C G Y G ++ T +G C+ W QS ++ P K + L N CRNPD Sbjct: 86 IRMRDVVLFEKKVYLS------ECK-TGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATH--PSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHC----SGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPD 238 HSP 2 Score: 51.9878 bits (123), Expect = 1.004e-7 Identity = 40/142 (28.17%), Postives = 58/142 (40.85%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G + + +G C +W + + S + + ++ NYCRNP PWC + WE C I C T G Y G++ T +G C+ W Q+ ++ N PE L N CRNPD Sbjct: 190 GENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKN--LKKNYCRNPDRELR-PWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPD 328 HSP 3 Score: 47.3654 bits (111), Expect = 4.746e-6 Identity = 32/116 (27.59%), Postives = 48/116 (41.38%), Query Frame = 2 Query: 230 IETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC---------------IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511 + NYCRNP + GPWC + + WE+C+++ C + + + D G Y G T TG C+ W Q + + F ++ G N CRNPD Sbjct: 421 LTMNYCRNP-DADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPD 535
BLAST of Prothrombin vs. Ensembl Human
Match: HGF (hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893]) HSP 1 Score: 71.633 bits (174), Expect = 1.690e-14 Identity = 49/148 (33.11%), Postives = 68/148 (45.95%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511 I NC I GR Y G +++K+G C W +E S Y ++ NYCRNP GPWC + +E C I C + T G Y G ++ T++GKIC+ W Q+ + +P+K F N CRNPD Sbjct: 125 IRNC-IIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFD--DNYCRNPD 264 HSP 2 Score: 62.003 bits (149), Expect = 4.251e-11 Identity = 47/154 (30.52%), Postives = 66/154 (42.86%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-----------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517 +T +G Y G + +++G+ C W + + Y D + NYCRNP P PWC + WE+C I++C N DTD +G Y G +N G C+ W Q + + PE K L N CRNPD S Sbjct: 212 MTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKG--FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCAD--NTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS 360 HSP 3 Score: 52.373 bits (124), Expect = 7.940e-8 Identity = 27/98 (27.55%), Postives = 48/98 (48.98%), Query Frame = 2 Query: 62 LSYFTEIENCKIT-------THGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 + Y ++I NC ++ +G+ Y+G + +++G C W K E + + S + NYCRNP + +GPWC ++ W++C I C Sbjct: 374 VGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNM--EDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC 469
BLAST of Prothrombin vs. Ensembl Human
Match: HGF (hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893]) HSP 1 Score: 69.707 bits (169), Expect = 4.022e-14 Identity = 47/146 (32.19%), Postives = 67/146 (45.89%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 I NC I GR Y G +++K+G C W + +I + Y ++ NYCRNP GPWC + +E C I C + T G Y G ++ T++GKIC+ W Q+ + PE+ N CRNPD Sbjct: 125 IRNC-IIGKGRSYKGTVSITKSGIKCQPW-----SSMIPHEHSY--RGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPD 259
BLAST of Prothrombin vs. Ensembl Fly
Match: Nrk (gene:FBgn0020391 transcript:FBtr0087728) HSP 1 Score: 56.6102 bits (135), Expect = 1.346e-9 Identity = 31/79 (39.24%), Postives = 43/79 (54.43%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIE-TNYCRNPTNFPNGPWC-IVDESILEWEHCHIRSC 334 +GR Y+G NVSK+G PC W +Y ++ ++ ++E NYCRN PWC VDES+ W+HC I C Sbjct: 223 NGRFYMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFH---QLLEGENYCRNAGGEEPHPWCYTVDESV-RWQHCDIPMC 297
BLAST of Prothrombin vs. Ensembl Fly
Match: Ror (gene:FBgn0010407 transcript:FBtr0079978) HSP 1 Score: 53.5286 bits (127), Expect = 1.541e-8 Identity = 33/79 (41.77%), Postives = 39/79 (49.37%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVD---ESILEWEHCHIRSC 334 G Y G NVS +G+PCL W + EI D +I NYCRNP + N PWC VD E I+E C I C Sbjct: 242 GSTYRGVANVSASGKPCLRWS-WLMKEI-------SDFPELIGQNYCRNPGSVENSPWCFVDSSRERIIEL--CDIPKC 310
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: plg (plasminogen [Source:ZFIN;Acc:ZDB-GENE-030131-1411]) HSP 1 Score: 73.1738 bits (178), Expect = 3.561e-15 Identity = 47/166 (28.31%), Postives = 77/166 (46.39%), Query Frame = 2 Query: 26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511 ++ AL + ++L I G +Y G + +K+G+ C W+ + + + Y + +E+N+CRNP GPWC + WEHC+I+ C +E C G Y G ++ T +G C+ W Q Y ++ P+K + N CRNPD Sbjct: 96 MSAALYEKKEYLLECVNGI--------GMDYRGTKSKTKSGKTCQRWEGTFPHVPNITPRAY--PKADLESNFCRNPDGDKGGPWCYTTDPEKRWEHCNIQDCTEECMQC----SGENYRGKISTTVSGFTCQRWDSQQPQNHGYLPSALPDKYLEE--NYCRNPD 245 HSP 2 Score: 66.2402 bits (160), Expect = 9.660e-13 Identity = 46/142 (32.39%), Postives = 59/142 (41.55%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER-----NWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G + + +G C W + S D +E NYCRNP P PWC WE C I C E + +G+ Y G ++ T TGK C+ W QS + + PE L GN CRNPD Sbjct: 197 GENYRGKISTTVSGFTCQRWDSQQPQNHGYLPSALPD--KYLEENYCRNPDGEPR-PWCFTTSPSKRWEACAIPRCTTEPPTIVPELTCASGEGSSYRGTISVTITGKTCQQWTSQSPHKHSRSPENYPCKGLDGNYCRNPD 335 HSP 3 Score: 58.5362 bits (140), Expect = 3.703e-10 Identity = 42/147 (28.57%), Postives = 63/147 (42.86%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G +V+ G+ C W + ++ Y ++ NYCRNP N PWC + WE+C + SC I + C + D G+ Y G ++ T +GK C+ W + + P+ L N CRNPD Sbjct: 287 GSSYRGTISVTITGKTCQQWTSQSPHKHSRSPENY--PCKGLDGNYCRNPDNE-RSPWCYTTDPETRWEYCSVPSCGDQPRPEEPVIPQGEECYEGD-GSSYRGVMSETISGKKCQFWTSMEPHRHSKTPQNFPKADLRRNLCRNPD 429
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: mst1 (macrophage stimulating 1 [Source:ZFIN;Acc:ZDB-GENE-020806-3]) HSP 1 Score: 71.2478 bits (173), Expect = 1.601e-14 Identity = 52/161 (32.30%), Postives = 77/161 (47.83%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC---IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPDMS 517 I CK IT +G +Y G + + +G+ C W +++ ++ I Y D + ++ NYCRNP P PWC + +E E C I C K R T +G +Y G +N T +G C+ W Q + FP K+++ G N CRNPD S Sbjct: 184 IPQCKDEVCITCNGEDYRGQVDHTVSGKECQRWDQQFPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPTMERESCDISKCPEFPKRRLRSSYTTNCFRGRGEDYRGKVNETTSGIPCQRWDAQKPHEHPFFP-KTYECKGLEENYCRNPDGS 340 HSP 2 Score: 68.9366 bits (167), Expect = 9.011e-14 Identity = 48/145 (33.10%), Postives = 67/145 (46.21%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPW----IIQSNYSENSFPEKSFQLVGNKCRNPDMS 517 I G +Y G + + +GR C W ++ + D T+ +E NYCRNP GPWC + +E C+I C E T G +Y G ++ T +GK C+ W Q Y +P+KS L N CRNPD S Sbjct: 112 IVGKGEDYRGKVSTTTSGRTCQQWWSKFPH----DHRWTPSATNGLELNYCRNPDGDRIGPWCYTTDPERRYESCNIPQCKDEVCI---TCNGEDYRGQVDHTVSGKECQRWDQQFPHQHIYQPEKYPDKS--LDDNYCRNPDAS 247 HSP 3 Score: 51.6026 bits (122), Expect = 1.016e-7 Identity = 41/141 (29.08%), Postives = 60/141 (42.55%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIK--ERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQ--LVGNKCRNPD 511 G +Y G N + +G PC W + +E Y +E NYCRNP + PWC + C I+ C E C + + G Y G + T+ G +C+ W I + + P+ + L N CRNPD Sbjct: 289 RGEDYRGKVNETTSGIPCQRWDAQKPHEHPFFPKTY--ECKGLEENYCRNP-DGSEAPWCFTSLPEMRTALCLQIKRCADDIEAEDCYN-EIGKNYRGVVRKTRKGILCQKWSINTPHKTKINPKTHPEANLTDNYCRNPD 425 HSP 4 Score: 46.595 bits (109), Expect = 5.735e-6 Identity = 29/107 (27.10%), Postives = 48/107 (44.86%), Query Frame = 2 Query: 26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER 346 + TAL LQ E E+C G+ Y G ++ G C W ++ ++ + + + NYCRNP +GPWC + E+++C I+ C E+ Sbjct: 352 MRTALCLQIKRCADDI-EAEDC-YNEIGKNYRGVVRKTRKGILCQKWSINTPHKTKINPKTHPEAN--LTDNYCRNPDGDHHGPWCYTSDPKTEFDYCAIKQCAGEK 454
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: hgfb (hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GENE-041014-3]) HSP 1 Score: 63.1586 bits (152), Expect = 1.038e-11 Identity = 42/147 (28.57%), Postives = 65/147 (44.22%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPD 511 +T +G Y G + +++GR C W E ++ I Y D ++ NYCRNP PWC + WE+C+I+ C + + + +G Y G + T G C+ W Q + + P+ L N CRNPD Sbjct: 191 MTCNGESYRGPLDHTESGRECQRWDLEEPHKHIFHPKRYPDKG--LKDNYCRNPDGRQR-PWCFTTDPSTPWEYCNIKQCDSDNSGDVENTTTCFRGRGEGYRGTIGITPDGVTCQRWDAQFPHRHSYTPQNYHCKDLRENYCRNPD 334 HSP 2 Score: 60.4622 bits (145), Expect = 7.733e-11 Identity = 43/145 (29.66%), Postives = 65/145 (44.83%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNE--IIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSE----NSFPEKSFQLVGNKCRNPD 511 I +G Y G +V+K+G C W + +E + + D + N CRNP N GPWC + L + C I C + T G Y G L+ T++G+ C+ W ++ + +P+K L N CRNPD Sbjct: 108 IIGNGLNYKGKRSVTKSGVQCQLWNSKMPHEHNFLPQRHKHRD----LRDNLCRNPDNTTTGPWCFTTDPKLRHQDCSIPQCSEVECM---TCNGESYRGPLDHTESGRECQRWDLEEPHKHIFHPKRYPDKG--LKDNYCRNPD 243 HSP 3 Score: 46.595 bits (109), Expect = 5.649e-6 Identity = 40/150 (26.67%), Postives = 61/150 (40.67%), Query Frame = 2 Query: 77 EIENCKITTHGRE--YVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKDTDKGTE--YLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511 ++EN GR Y G ++ +G C W ++ + Y + NYCRNP + PWC + + C +I C + + KG Y G + T++G C PW S +E + + GN CRNPD Sbjct: 274 DVENTTTCFRGRGEGYRGTIGITPDGVTCQRWDAQFPHRHSYTPQNYH--CKDLRENYCRNPDGR-HLPWCFTTDPTVPIAFCTNIPRCGVKPPEPGECYKGIGDMYNGHRSKTRSGIPCAPWKDHSESNERDVNLLTTEQAGNFCRNPD 420
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: hgfa (hepatocyte growth factor a [Source:ZFIN;Acc:ZDB-GENE-041014-2]) HSP 1 Score: 61.2326 bits (147), Expect = 4.064e-11 Identity = 42/141 (29.79%), Postives = 62/141 (43.97%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPD 511 I G Y G + +K G C SW +E + + S + N+CRNP N PNGPWC + + + C + C C + G Y G ++ T++GK C+ W Q + P + L N CRNP+ Sbjct: 114 IIGSGVNYKGRRSFTKTGITCQSWNMSVPHEHNFKPTRH--KKSDLRQNFCRNPDNDPNGPWCFTELTETRHQDCGLPQCSDVE--CMKCN-GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKGLDDNFCRNPN 249 HSP 2 Score: 53.1434 bits (126), Expect = 2.491e-8 Identity = 39/145 (26.90%), Postives = 62/145 (42.76%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517 G Y G + +++G+ C W + ++ + ++ N+CRNP N PWC + WE+C+I C + + + +G Y G +N T G C+ W S + + P K L N CRNPD S Sbjct: 201 GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKG--LDDNFCRNPNNDVR-PWCYTMDKNTPWEYCNISVCDSDSDVEVEVTSSCFRGQGEGYRGTVNVTPAGVTCQRWDALSPHIHSYTPHNYKCKDLRENYCRNPDGS 342 HSP 3 Score: 49.2914 bits (116), Expect = 6.159e-7 Identity = 41/149 (27.52%), Postives = 63/149 (42.28%), Query Frame = 2 Query: 74 TEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKD--TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511 E+ + G Y G NV+ G C W + L+ I + + + NYCRNP + PWC ++ + C +I C E + + D G Y G+L+ T++G C W + + + S L N CRNPD Sbjct: 281 VEVTSSCFRGQGEGYRGTVNVTPAGVTCQRW--DALSPHIHSYTPHNYKCKDLRENYCRNP-DGSEIPWCFTTDAKVRKAFCTNIPRCESESSDSTECYEDNGESYRGNLSKTRSGIPCGLWSDHTFRRDTRSAKASAGLELNLCRNPD 426 HSP 4 Score: 47.7506 bits (112), Expect = 2.210e-6 Identity = 22/76 (28.95%), Postives = 36/76 (47.37%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 G Y G + +++G PC W + D+ ++ +E N CRNP +GPWC S + W++C + C Sbjct: 380 GESYRGNLSKTRSGIPCGLWS----DHTFRRDTRSAKASAGLELNLCRNPDRDKHGPWCYTSNSSIPWDYCGLERC 451
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: hgfa (hepatocyte growth factor a [Source:ZFIN;Acc:ZDB-GENE-041014-2]) HSP 1 Score: 61.2326 bits (147), Expect = 4.291e-11 Identity = 42/141 (29.79%), Postives = 62/141 (43.97%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPD 511 I G Y G + +K G C SW +E + + S + N+CRNP N PNGPWC + + + C + C C + G Y G ++ T++GK C+ W Q + P + L N CRNP+ Sbjct: 114 IIGSGVNYKGRRSFTKTGITCQSWNMSVPHEHNFKPTRH--KKSDLRQNFCRNPDNDPNGPWCFTELTETRHQDCGLPQCSDVE--CMKCN-GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKGLDDNFCRNPN 249 HSP 2 Score: 53.1434 bits (126), Expect = 2.579e-8 Identity = 39/145 (26.90%), Postives = 62/145 (42.76%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517 G Y G + +++G+ C W + ++ + ++ N+CRNP N PWC + WE+C+I C + + + +G Y G +N T G C+ W S + + P K L N CRNPD S Sbjct: 201 GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKG--LDDNFCRNPNNDVR-PWCYTMDKNTPWEYCNISVCDSDSDVEVEVTSSCFRGQGEGYRGTVNVTPAGVTCQRWDALSPHIHSYTPHNYKCKDLRENYCRNPDGS 342 HSP 3 Score: 49.2914 bits (116), Expect = 6.378e-7 Identity = 41/149 (27.52%), Postives = 63/149 (42.28%), Query Frame = 2 Query: 74 TEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKD--TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511 E+ + G Y G NV+ G C W + L+ I + + + NYCRNP + PWC ++ + C +I C E + + D G Y G+L+ T++G C W + + + S L N CRNPD Sbjct: 281 VEVTSSCFRGQGEGYRGTVNVTPAGVTCQRW--DALSPHIHSYTPHNYKCKDLRENYCRNP-DGSEIPWCFTTDAKVRKAFCTNIPRCESESSDSTECYEDNGESYRGNLSKTRSGIPCGLWSDHTFRRDTRSAKASAGLELNLCRNPD 426 HSP 4 Score: 47.7506 bits (112), Expect = 2.005e-6 Identity = 26/101 (25.74%), Postives = 44/101 (43.56%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKT 409 G Y G + +++G PC W + D+ ++ +E N CRNP +GPWC S + W++C + C + C K T +G + + Sbjct: 380 GESYRGNLSKTRSGIPCGLWS----DHTFRRDTRSAKASAGLELNLCRNPDRDKHGPWCYTSNSSIPWDYCGLERCGGPKPSCF-IHKTTRIVGGMRVQRA 475
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056]) HSP 1 Score: 77.7962 bits (190), Expect = 1.409e-16 Identity = 52/159 (32.70%), Postives = 84/159 (52.83%), Query Frame = 2 Query: 47 QSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 Q S +L Y+ I +C + +G Y G + +KNGR C W+ ++ ++ + + + +E NYCRNP + P G WC + + ++C I+ C E C T G +Y G ++ T++GK C+ W +Q+ ++ PEK L N CRNPD S Sbjct: 56 QCSDLLDYY--IRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 204 HSP 2 Score: 61.2326 bits (147), Expect = 7.323e-11 Identity = 49/166 (29.52%), Postives = 76/166 (45.78%), Query Frame = 2 Query: 59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCI-KERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 I + I+ C+ +T +G +Y G + +++G+ C W + + Y D + ++ NYCRNP + PWC + +E E C I C K+R +T ++G Y G N T +G C+ W Q+ + PEK L N CRNPD S Sbjct: 134 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCTEKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 296
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056]) HSP 1 Score: 75.0998 bits (183), Expect = 1.018e-15 Identity = 51/165 (30.91%), Postives = 85/165 (51.52%), Query Frame = 2 Query: 38 LLLQSSFILSYFTE---IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 +LLQ + + + I +C + +G Y G + +KNGR C W+ ++ ++ + + + +E NYCRNP + P G WC + + ++C I+ C E C T G +Y G ++ T++GK C+ W +Q+ ++ PEK L N CRNPD S Sbjct: 100 VLLQRNVQYDLYQKKDYIRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 256 HSP 2 Score: 65.4698 bits (158), Expect = 2.561e-12 Identity = 49/165 (29.70%), Postives = 76/165 (46.06%), Query Frame = 2 Query: 59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 I + I+ C+ +T +G +Y G + +++G+ C W + + Y D + ++ NYCRNP + PWC + +E E C I C K+R +T ++G Y G N T +G C+ W Q+ + PEK L N CRNPD S Sbjct: 186 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCKKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 347 HSP 3 Score: 47.7506 bits (112), Expect = 2.762e-6 Identity = 40/140 (28.57%), Postives = 58/140 (41.43%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE--RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF-QLVGNKCRNPD 511 G Y G N + +G PC W + + Y ++ NYCRNP + PWC + +C I+ C + C + G Y G ++ T+ G C+ W + N E S + L GN CRNPD Sbjct: 296 RGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKY--PCKGLDENYCRNP-DGSEAPWCFTTLPGMRMAYCFQIKRCTDDVVEPGCYHGN-GELYNGRVSKTRKGITCRKWEEKRNDLELSLDQPYLVPLEGNYCRNPD 431
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056]) HSP 1 Score: 75.0998 bits (183), Expect = 1.085e-15 Identity = 51/165 (30.91%), Postives = 85/165 (51.52%), Query Frame = 2 Query: 38 LLLQSSFILSYFTE---IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 +LLQ + + + I +C + +G Y G + +KNGR C W+ ++ ++ + + + +E NYCRNP + P G WC + + ++C I+ C E C T G +Y G ++ T++GK C+ W +Q+ ++ PEK L N CRNPD S Sbjct: 100 VLLQRNVQYDLYQKKDYIRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 256 HSP 2 Score: 65.0846 bits (157), Expect = 3.006e-12 Identity = 49/165 (29.70%), Postives = 76/165 (46.06%), Query Frame = 2 Query: 59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 I + I+ C+ +T +G +Y G + +++G+ C W + + Y D + ++ NYCRNP + PWC + +E E C I C K+R +T ++G Y G N T +G C+ W Q+ + PEK L N CRNPD S Sbjct: 186 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCKKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 347 HSP 3 Score: 47.7506 bits (112), Expect = 3.116e-6 Identity = 40/140 (28.57%), Postives = 58/140 (41.43%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE--RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF-QLVGNKCRNPD 511 G Y G N + +G PC W + + Y ++ NYCRNP + PWC + +C I+ C + C + G Y G ++ T+ G C+ W + N E S + L GN CRNPD Sbjct: 296 RGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKY--PCKGLDENYCRNP-DGSEAPWCFTTLPGMRMAYCFQIKRCTDDVVEPGCYHGN-GELYNGRVSKTRKGITCRKWEEKRNDLELSLDQPYLVPLEGNYCRNPD 431
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056]) HSP 1 Score: 75.0998 bits (183), Expect = 1.205e-15 Identity = 51/165 (30.91%), Postives = 85/165 (51.52%), Query Frame = 2 Query: 38 LLLQSSFILSYFTE---IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 +LLQ + + + I +C + +G Y G + +KNGR C W+ ++ ++ + + + +E NYCRNP + P G WC + + ++C I+ C E C T G +Y G ++ T++GK C+ W +Q+ ++ PEK L N CRNPD S Sbjct: 87 VLLQRNVQYDLYQKKDYIRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 243 HSP 2 Score: 61.2326 bits (147), Expect = 7.552e-11 Identity = 49/166 (29.52%), Postives = 76/166 (45.78%), Query Frame = 2 Query: 59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCI-KERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517 I + I+ C+ +T +G +Y G + +++G+ C W + + Y D + ++ NYCRNP + PWC + +E E C I C K+R +T ++G Y G N T +G C+ W Q+ + PEK L N CRNPD S Sbjct: 173 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCTEKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 335 HSP 3 Score: 47.7506 bits (112), Expect = 3.113e-6 Identity = 40/140 (28.57%), Postives = 58/140 (41.43%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE--RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF-QLVGNKCRNPD 511 G Y G N + +G PC W + + Y ++ NYCRNP + PWC + +C I+ C + C + G Y G ++ T+ G C+ W + N E S + L GN CRNPD Sbjct: 284 RGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKY--PCKGLDENYCRNP-DGSEAPWCFTTLPGMRMAYCFQIKRCTDDVVEPGCYHGN-GELYNGRVSKTRKGITCRKWEEKRNDLELSLDQPYLVPLEGNYCRNPD 419
BLAST of Prothrombin vs. Ensembl Xenopus
Match: ENSXETT00000037773.1 (plasminogen [Source:NCBI gene;Acc:100496227]) HSP 1 Score: 73.9442 bits (180), Expect = 3.077e-15 Identity = 53/174 (30.46%), Postives = 83/174 (47.70%), Query Frame = 2 Query: 2 ANLMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511 A L+F FL + F Y E IT G++Y G + + +G+ C +W + + YF + E N+CRNP N NGPWC + + +E+C+I C ++ C G Y G ++ T +G C+ W Q+ YS ++ P+K+ + N CRNPD Sbjct: 6 ATLLFQTFLKRCKI-HMYFFTVYLKEC----ITGKGKDYRGTESKTHSGKTCQNWTGSFPHV-----PKYFPNAGL-EGNFCRNPDNDLNGPWCYTTDFSVRFEYCNIPQCEEDCMHC----SGENYRGRISKTASGTECQNWDSQTPHSHGYSPSNIPDKNLER--NYCRNPD 162 HSP 2 Score: 65.855 bits (159), Expect = 1.683e-12 Identity = 45/151 (29.80%), Postives = 68/151 (45.03%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDK----------GTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 ++ G Y G V+ +G+ C W + ++ I Y +E NYCRNP + + PWC +S WE+C+I SC T+ G++Y G T +GK C+PW Q+ + P+ + L N CRNPD Sbjct: 200 LSGKGENYSGNIAVTASGKTCQEWSLQVPHKHIRTPDNY--PCKNLEKNYCRNP-DGESMPWCYTTDSETRWEYCNIPSCDAPTVNAAPTNPSTILECYDGNGSKYRGTAYITVSGKKCQPWNSQTPHKHTKMPDNFPNAGLEQNYCRNPD 347 HSP 3 Score: 62.7734 bits (151), Expect = 2.232e-11 Identity = 43/142 (30.28%), Postives = 59/142 (41.55%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKD-----TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G + + +G C +W + + S D +E NYCRNP P PWC WEHC+I C + KG Y G++ T +GK C+ W +Q + P+ L N CRNPD Sbjct: 114 GENYRGRISKTASGTECQNWDSQTPHSHGYSPSNIPDKN--LERNYCRNPDGEPR-PWCFTTNPNKRWEHCNIPRCTTNPPTSAPGVQCLSGKGENYSGNIAVTASGKTCQEWSLQVPHKHIRTPDNYPCKNLEKNYCRNPD 252 HSP 4 Score: 59.3066 bits (142), Expect = 3.434e-10 Identity = 44/155 (28.39%), Postives = 70/155 (45.16%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNE-IIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIK----ERNWCKD-----------TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511 +G +Y G ++ +G+ C W + ++ M D+ + +E NYCRNP + GPWC ++ + WE+C ++ C + E+ + KG +Y G + T G IC+ W QS SF + G N CRNPD Sbjct: 298 NGSKYRGTAYITVSGKKCQPWNSQTPHKHTKMPDNF---PNAGLEQNYCRNP-DEDKGPWCYTTDASVRWEYCSLKKCSELPSTEQRPVQTTKITTITTNCIVSKGEDYRGIKSTTLNGHICQAWSSQSPQEHASFTPITHPQSGLESNYCRNPD 448 HSP 5 Score: 53.1434 bits (126), Expect = 4.514e-8 Identity = 31/84 (36.90%), Postives = 42/84 (50.00%), Query Frame = 2 Query: 86 NCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIV-DESILEWEHCHIRSC 334 NC I + G +Y G + + NG C +W + E I S +E+NYCRNP NGPWC V ++WE+C I C Sbjct: 393 NC-IVSKGEDYRGIKSTTLNGHICQAWSSQSPQEHASFTPITH-PQSGLESNYCRNPDGDINGPWCFVTTPGTVKWEYCDIPRC 474
BLAST of Prothrombin vs. Ensembl Mouse
Match: Mst1 (macrophage stimulating 1 (hepatocyte growth factor-like) [Source:MGI Symbol;Acc:MGI:96080]) HSP 1 Score: 77.411 bits (189), Expect = 1.225e-16 Identity = 47/144 (32.64%), Postives = 70/144 (48.61%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I +G Y G + G PC +W + + N D Y T + +E N+CRNP P GPWC + ++ C I++C R G +Y G+++ T++G+ C+ W +Q +S PEK L N CRNPD S Sbjct: 111 IMDNGVSYRGTVARTAGGLPCQAWSRRFPN-----DHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTC---REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGS 246 HSP 2 Score: 69.707 bits (169), Expect = 5.518e-14 Identity = 50/159 (31.45%), Postives = 73/159 (45.91%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC---IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I+ C+ + +G +Y G +V+++GR C W ++ + + D ++ NYCRNP PWC + +E E C + SC + RN K + KG +Y G N T G C+ W QS + PEK L N CRNPD S Sbjct: 183 IKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKD--LKDNYCRNPDG-SERPWCYTTDPNVEREFCDLPSCGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGS 338
BLAST of Prothrombin vs. Ensembl Mouse
Match: Mst1 (macrophage stimulating 1 (hepatocyte growth factor-like) [Source:MGI Symbol;Acc:MGI:96080]) HSP 1 Score: 77.411 bits (189), Expect = 1.228e-16 Identity = 47/144 (32.64%), Postives = 70/144 (48.61%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I +G Y G + G PC +W + + N D Y T + +E N+CRNP P GPWC + ++ C I++C R G +Y G+++ T++G+ C+ W +Q +S PEK L N CRNPD S Sbjct: 111 IMDNGVSYRGTVARTAGGLPCQAWSRRFPN-----DHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTC---REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGS 246 HSP 2 Score: 66.2402 bits (160), Expect = 8.923e-13 Identity = 50/168 (29.76%), Postives = 73/168 (43.45%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC------------IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I+ C+ + +G +Y G +V+++GR C W ++ + + D ++ NYCRNP PWC + +E E C + SC + RN K + KG +Y G N T G C+ W QS + PEK L N CRNPD S Sbjct: 183 IKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKD--LKDNYCRNPDG-SERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGS 347
BLAST of Prothrombin vs. Ensembl Mouse
Match: Plg (plasminogen [Source:MGI Symbol;Acc:MGI:97620]) HSP 1 Score: 70.8626 bits (172), Expect = 2.545e-14 Identity = 48/170 (28.24%), Postives = 78/170 (45.88%), Query Frame = 2 Query: 8 LMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 + N ++ + ++ + + CK T G Y G + +K+G C W + + + + S +E NYCRNP N GPWC + +++C+I C +E +C G +Y G ++ T +G C+ W QS ++ P K S L N CRNPD Sbjct: 76 MAENSKTSSIIRMRDVILFEKRVYLSECK-TGIGNGYRGTMSRTKSGVACQKWGATFPH--VPNYSPSTHPNEGLEENYCRNPDNDEQGPWCYTTDPDKRYDYCNIPECEEECMYC----SGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKMNYCRNPD 238 HSP 2 Score: 61.6178 bits (148), Expect = 3.735e-11 Identity = 41/159 (25.79%), Postives = 68/159 (42.77%), Query Frame = 2 Query: 101 THGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC-------------IKERNWCKDTD------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511 + G+ Y G ++ + G+ C SW + + + D +E NYCRNP + GPWC + + WE+C+++ C +E + D++ G +Y G T G C+ W Q + + F ++ G N CRNPD Sbjct: 380 SDGQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPENFPDAG--LEMNYCRNP-DGDKGPWCYTTDPSVRWEYCNLKRCSETGGSVVELPTVSQEPSGPSDSETDCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPD 535 HSP 3 Score: 59.3066 bits (142), Expect = 2.361e-10 Identity = 41/142 (28.87%), Postives = 62/142 (43.66%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G +Y G + + +G C +W + + + + + ++ NYCRNP P PWC + WE+C I C T +G Y G ++ T +GK C+ W Q+ + N PE L N CRNPD Sbjct: 190 GEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKF--PSKNLKMNYCRNPDGEPR-PWCFTTDPTKRWEYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENFPCKNLEENYCRNPD 328 HSP 4 Score: 58.151 bits (139), Expect = 6.075e-10 Identity = 47/162 (29.01%), Postives = 67/162 (41.36%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN------------------WCKDTDKGTEYLGDLNFTKTGKICKPWII-----QSNYSENSFPEKSFQLVGNKCRNPD 511 + G Y G +V+ +G+ C W ++ + + +E NYCRNP + PWC +S L WE+C I SC + C +D G Y G + T TGK C+ W S EN FP+ ++ N CRNPD Sbjct: 276 LKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENF--PCKNLEENYCRNP-DGETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDSSVPPEEQTPVVQECYQSD-GQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPEN-FPDAGLEM--NYCRNPD 430 HSP 5 Score: 48.1358 bits (113), Expect = 1.559e-6 Identity = 27/81 (33.33%), Postives = 39/81 (48.15%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTT---SIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCI 337 +G++Y G T V+ G PC W + + SI+ T + +E NYCRNP NGPWC +++C I C Sbjct: 485 NGKDYRGKTAVTAAGTPCQGWAAQEPHR----HSIFTPQTNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLYDYCDIPLCA 561
BLAST of Prothrombin vs. Ensembl Mouse
Match: Hgf (hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079]) HSP 1 Score: 68.1662 bits (165), Expect = 2.316e-13 Identity = 47/148 (31.76%), Postives = 66/148 (44.59%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511 I NC I G Y G +++K+G C W +E S Y ++ NYCRNP GPWC + +E C I C + T G Y G ++ T++GK C+ W Q+ + +P+K F N CRNPD Sbjct: 126 IRNC-IIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFD--DNYCRNPD 265 HSP 2 Score: 57.7658 bits (138), Expect = 9.089e-10 Identity = 44/152 (28.95%), Postives = 67/152 (44.08%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517 +T +G Y G + +++G+ C W ++ + Y D + NYCRNP P PWC + WE+C I++C + E + +T +G Y G N G C+ W Q + + PE K L N CRNPD + Sbjct: 213 MTCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKG--FDDNYCRNPDGKPR-PWCYTLDPDTPWEYCAIKTCAHSAVNETDVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDGA 361 HSP 3 Score: 51.9878 bits (123), Expect = 8.201e-8 Identity = 26/98 (26.53%), Postives = 48/98 (48.98%), Query Frame = 2 Query: 62 LSYFTEIENCKITT-------HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 + Y ++I C +++ +G+ Y+G + +++G C W K E + + S + NYCRNP + +GPWC ++ W++C I C Sbjct: 375 VGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNM--EDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC 470
BLAST of Prothrombin vs. Ensembl Mouse
Match: Hgf (hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079]) HSP 1 Score: 68.1662 bits (165), Expect = 2.316e-13 Identity = 47/148 (31.76%), Postives = 66/148 (44.59%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511 I NC I G Y G +++K+G C W +E S Y ++ NYCRNP GPWC + +E C I C + T G Y G ++ T++GK C+ W Q+ + +P+K F N CRNPD Sbjct: 126 IRNC-IIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFD--DNYCRNPD 265 HSP 2 Score: 57.7658 bits (138), Expect = 9.089e-10 Identity = 44/152 (28.95%), Postives = 67/152 (44.08%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517 +T +G Y G + +++G+ C W ++ + Y D + NYCRNP P PWC + WE+C I++C + E + +T +G Y G N G C+ W Q + + PE K L N CRNPD + Sbjct: 213 MTCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKG--FDDNYCRNPDGKPR-PWCYTLDPDTPWEYCAIKTCAHSAVNETDVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDGA 361 HSP 3 Score: 51.9878 bits (123), Expect = 8.201e-8 Identity = 26/98 (26.53%), Postives = 48/98 (48.98%), Query Frame = 2 Query: 62 LSYFTEIENCKITT-------HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 + Y ++I C +++ +G+ Y+G + +++G C W K E + + S + NYCRNP + +GPWC ++ W++C I C Sbjct: 375 VGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNM--EDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC 470
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|P26928|HGFL_MOUSE (Hepatocyte growth factor-like protein OS=Mus musculus OX=10090 GN=Mst1 PE=2 SV=2) HSP 1 Score: 77.411 bits (189), Expect = 8.588e-16 Identity = 47/144 (32.64%), Postives = 70/144 (48.61%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I +G Y G + G PC +W + + N D Y T + +E N+CRNP P GPWC + ++ C I++C R G +Y G+++ T++G+ C+ W +Q +S PEK L N CRNPD S Sbjct: 111 IMDNGVSYRGTVARTAGGLPCQAWSRRFPN-----DHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTC---REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGS 246 HSP 2 Score: 66.2402 bits (160), Expect = 6.242e-12 Identity = 50/168 (29.76%), Postives = 73/168 (43.45%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC------------IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I+ C+ + +G +Y G +V+++GR C W ++ + + D ++ NYCRNP PWC + +E E C + SC + RN K + KG +Y G N T G C+ W QS + PEK L N CRNPD S Sbjct: 183 IKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKD--LKDNYCRNPDG-SERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGS 347
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|P26927|HGFL_HUMAN (Hepatocyte growth factor-like protein OS=Homo sapiens OX=9606 GN=MST1 PE=1 SV=2) HSP 1 Score: 77.411 bits (189), Expect = 1.030e-15 Identity = 48/145 (33.10%), Postives = 70/145 (48.28%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN-WCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQ--LVGNKCRNPDMS 517 I +G Y G + G PC +W ++ N D Y T + +E N+CRNP P GPWC + + ++ C I+SC + WC G EY G ++ T++G+ C+ W +Q + P K L N CRNPD S Sbjct: 111 IMNNGVGYRGTMATTVGGLPCQAWSHKFPN-----DHKYTPTLRNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWC----NGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGS 246 HSP 2 Score: 63.929 bits (154), Expect = 4.153e-11 Identity = 46/159 (28.93%), Postives = 70/159 (44.03%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517 I++C+ + +G EY G + +++GR C W ++ ++ + + D ++ NYCRNP PWC + +E E C + C E ++ KG Y G N T G C+ W Q + PEK L N CRNPD S Sbjct: 183 IKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQG--LDDNYCRNPDG-SERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGS 338 HSP 3 Score: 48.9062 bits (115), Expect = 5.835e-6 Identity = 39/139 (28.06%), Postives = 57/139 (41.01%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCH-IRSCIKE-RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN-SF-PEKSFQLVGNKCRNPD 511 G Y G N + G PC W + ++ Y + N+CRNP PWC + C+ IR C + R G +Y G ++ T+ G C+ W ++ + +F E QL N CRNPD Sbjct: 288 GEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKY--ACKDLRENFCRNPDG-SEAPWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPD 423
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|Q29485|PLMN_ERIEU (Plasminogen OS=Erinaceus europaeus OX=9365 GN=PLG PE=2 SV=1) HSP 1 Score: 75.0998 bits (183), Expect = 6.290e-15 Identity = 49/160 (30.63%), Postives = 74/160 (46.25%), Query Frame = 2 Query: 38 LLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 L ++ + + CK+ +G+ Y G + +K G C W E ++ S + + ++ NYCRNP N P GPWC + + +E+C I C E C G Y+G ++ T +G C+PW Q + P K S L N CRNPD Sbjct: 86 LRMRDVILFEKKMYLSECKVG-NGKYYRGTVSKTKTGLTCQKWSAETPHKPRF--SPDENPSEGLDQNYCRNPDNDPKGPWCYTMDPEVRYEYCEIIQCEDECMHC----SGQNYVGKISRTMSGLECQPWDSQIPHPHGFIPSKFPSKNLKMNYCRNPD 238 HSP 2 Score: 61.6178 bits (148), Expect = 2.306e-10 Identity = 44/160 (27.50%), Postives = 62/160 (38.75%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDK-------------------GTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 + +G Y G V+ +G C W ++ + Y ++ NYCRNP P PWC S + WE C I C+ + + +D G Y G + T TGK C+PW + + PE L N CRNPD Sbjct: 276 LMGNGEHYQGNVAVTVSGLTCQRWGEQSPHRHDRTPENY--PCKNLDENYCRNPDGEP-APWCFTTNSSVRWEFCKIPDCVSSASETEHSDAPVIVPPEQTPVVQECYQGNGQTYRGTSSTTITGKKCQPWTSMRPHRHSKTPENYPDADLTMNYCRNPD 432 HSP 3 Score: 56.225 bits (134), Expect = 2.010e-8 Identity = 42/142 (29.58%), Postives = 60/142 (42.25%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G+ YVG + + +G C W + + S + + ++ NYCRNP P PWC + WE+C I C T G Y G++ T +G C+ W QS + + PE L N CRNPD Sbjct: 190 GQNYVGKISRTMSGLECQPWDSQIPHPHGFIPSKF--PSKNLKMNYCRNPDGEPR-PWCFTMDRNKRWEYCDIPRCTTPPPPSGPTYQCLMGNGEHYQGNVAVTVSGLTCQRWGEQSPHRHDRTPENYPCKNLDENYCRNPD 328 HSP 4 Score: 53.5286 bits (127), Expect = 1.527e-7 Identity = 41/156 (26.28%), Postives = 61/156 (39.10%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------------------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSF-PEKSFQ--LVGNKCRNPD 511 G+ Y G ++ + G+ C W + Y D + NYCRNP + GPWC + + WE C+++ C ++ D G Y G T G C+ W Q + + F PE + + L N CRNPD Sbjct: 384 GQTYRGTSSTTITGKKCQPWTSMRPHRHSKTPENYPDAD--LTMNYCRNP-DGDKGPWCYTTDPSVRWEFCNLKKCSGTEMSATNSSPVQVSSASESSEQDCIIDNGKGYRGTKATTGAGTPCQAWAAQEPHRHSIFTPETNPRADLQENYCRNPD 536
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|O18783|PLMN_MACEU (Plasminogen OS=Macropus eugenii OX=9315 GN=PLG PE=2 SV=1) HSP 1 Score: 72.7886 bits (177), Expect = 3.281e-14 Identity = 49/146 (33.56%), Postives = 69/146 (47.26%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 + +CK + +GR Y G + +K+G C W + S Y D +E NYCRNP + GPWC + +E+C + C E C G Y G ++ T++G C+PW Q +S P K S L N CRNPD Sbjct: 100 LSDCK-SGNGRNYRGTLSKTKSGITCQKWSDLSPHVPNYAPSKYPDAG--LEKNYCRNPDDDVKGPWCYTTNPDIRYEYCDVPECEDECMHC----SGENYRGTISKTESGIECQPWDSQEPHSHEYIPSKFPSKDLKENYCRNPD 238 HSP 2 Score: 58.151 bits (139), Expect = 4.368e-9 Identity = 45/145 (31.03%), Postives = 63/145 (43.45%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSW--KKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKD-----TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511 G Y G + +++G C W ++ + +E I F + + E NYCRNP P PWC WE C+I C +G Y G + TK+G C+ W Q+ + N PE +F G N CRNPD Sbjct: 190 GENYRGTISKTESGIECQPWDSQEPHSHEYIPSK---FPSKDLKE-NYCRNPDGEPR-PWCFTSNPEKRWEFCNIPRCSSPPPPPGPMLQCLKGRGENYRGKIAVTKSGHTCQRWNKQTPHKHNRTPE-NFPCRGLDENYCRNPD 328 HSP 3 Score: 51.6026 bits (122), Expect = 7.528e-7 Identity = 40/152 (26.32%), Postives = 60/152 (39.47%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-----------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 + G Y G V+K+G C W K+ ++ + ++ NYCRNP PWC + E+C I SC + KG Y G + T +GK C+ W + + P+ + L+ N CRNPD Sbjct: 276 LKGRGENYRGKIAVTKSGHTCQRWNKQTPHKHNRTPENF--PCRGLDENYCRNPDGELE-PWCYTTNPDVRQEYCAIPSCGTSSPHTDRVEQSPVIQECYEGKGENYRGTTSTTISGKKCQAWSSMTPHQHKKTPDNFPNADLIRNYCRNPD 424
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|P00747|PLMN_HUMAN (Plasminogen OS=Homo sapiens OX=9606 GN=PLG PE=1 SV=2) HSP 1 Score: 72.7886 bits (177), Expect = 3.546e-14 Identity = 51/166 (30.72%), Postives = 75/166 (45.18%), Query Frame = 2 Query: 20 IFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 I + +L + LS CK T +G+ Y G + +KNG C W + + + + +E NYCRNP N P GPWC + +++C I C +E C G Y G ++ T +G C+ W QS ++ P K + L N CRNPD Sbjct: 86 IRMRDVVLFEKKVYLS------ECK-TGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATH--PSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHC----SGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPD 238 HSP 2 Score: 51.9878 bits (123), Expect = 4.821e-7 Identity = 40/142 (28.17%), Postives = 58/142 (40.85%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G + + +G C +W + + S + + ++ NYCRNP PWC + WE C I C T G Y G++ T +G C+ W Q+ ++ N PE L N CRNPD Sbjct: 190 GENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKN--LKKNYCRNPDRELR-PWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPD 328
BLAST of Prothrombin vs. TrEMBL
Match: R7VDJ1 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_224866 PE=4 SV=1) HSP 1 Score: 88.5817 bits (218), Expect = 2.342e-18 Identity = 51/164 (31.10%), Postives = 83/164 (50.61%), Query Frame = 2 Query: 38 LLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE-KSFQLVG------NKCRNP 508 LLL L+ E CK++ G EY G + + +GR C W + + +DD+ + + N+CRNP+N P GPWC+ + + W++C + C C+D G Y G L++T G IC+ W +Q + + + K+++L+G N CRNP Sbjct: 13 LLLLPWIPLAVAAE---CKLSQRGVEYSGTLSTTISGRTCQRWDVQTPHAHNVDDAHF--PNDDLAHNHCRNPSNDPGGPWCLTTDPAIRWQYCRVLFCSSCDRGCRDDKGGHFYKGLLSYTPDGVICQRWDVQDPHLHLGYSKLKNWKLLGDIGDNDNYCRNP 171
BLAST of Prothrombin vs. TrEMBL
Match: R7USY4 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_223208 PE=4 SV=1) HSP 1 Score: 86.2705 bits (212), Expect = 6.970e-17 Identity = 46/150 (30.67%), Postives = 69/150 (46.00%), Query Frame = 2 Query: 89 CKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER-----NWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511 C+ T G++YVG ++ +G C W ++Y E M + + + NYCRNP P GPWC + WE+C I C + CK G Y G ++ +++G+ C+ W Q + FPE + N CRNPD Sbjct: 150 CRNTQLGKDYVGQKQITTSGNECQRWDRQYPQEHSMQGNWFSEGDLHSAVNYCRNPDGEPGGPWCYTTNPDVRWEYCEIPFCPGADFNDIYSECKKDTLGRTYRGLVSTSRSGRECQYWTRQYPHEHRMNGKGFPEGNMAAAANFCRNPD 299 HSP 2 Score: 65.855 bits (159), Expect = 1.740e-9 Identity = 29/82 (35.37%), Postives = 42/82 (51.22%), Query Frame = 2 Query: 89 CKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 CK T GR Y G + S++GR C W ++Y +E M+ + + N+CRNP P GPWC + WE+C + C Sbjct: 243 CKKDTLGRTYRGLVSTSRSGRECQYWTRQYPHEHRMNGKGFPEGNMAAAANFCRNPDGEPEGPWCYTTDPETRWEYCVVDLC 324
BLAST of Prothrombin vs. TrEMBL
Match: H3CM77 (Prothrombin OS=Tetraodon nigroviridis OX=99883 PE=3 SV=1) HSP 1 Score: 85.8853 bits (211), Expect = 3.409e-16 Identity = 52/154 (33.77%), Postives = 79/154 (51.30%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-----------RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511 I+ G Y G N+SK+GR C WK + + II + + SI+E N+CRNP N +GPWC + ++ E C + +C + ++ ++ GT+Y GDL+ T G C W S ++ +K F +L+GNKCRNPD Sbjct: 112 ISGTGANYAGNVNISKSGRQCQHWKHNFPHPIIREFNAS-KPGSILEENFCRNPNNSADGPWCFTTDPTVQKETCRVPTCGEAFVPPTLAPTHIKSTACLSNYGTDYTGDLDVTAGGHPCLQW--SSPEAKALSKDKEFIPEVRLLGNKCRNPD 262
BLAST of Prothrombin vs. TrEMBL
Match: A0A2U9AVB1 (Putative prothrombin isoform 3 OS=Scophthalmus maximus OX=52904 GN=SMAX5B_002120 PE=3 SV=1) HSP 1 Score: 85.5001 bits (210), Expect = 4.001e-16 Identity = 51/159 (32.08%), Postives = 79/159 (49.69%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE---RNWCKDTDK--------GTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511 IE I G Y G N++++GRPC W+ + + I+ + +I + S ++ N+CRNP N P GPWC + ++ E C + +C ++ + D+ G +Y+GDL T G C W + + + PE LVGNKCRNPD Sbjct: 107 IEGQCIFGKGVNYDGNVNITQSGRPCQYWRHSFPHPIMREFNIS-EPNSNLDENFCRNPDNRPEGPWCFTQDPTVQKEACRVPTCGEDFVPSTVAPEPDQTEECLPNYGVDYVGDLAVTLGGHTCLQWSLPKLTALSVDKEFMPE--VPLVGNKCRNPD 262
BLAST of Prothrombin vs. TrEMBL
Match: A0A5E4MF17 (Immunoglobulin-like fold,Kringle,Kringle-like fold,Thrombospondin type-1 (TSP1) repeat,Kringle OS=Cinara cedri OX=506608 GN=CINCED_3A022495 PE=4 SV=1) HSP 1 Score: 85.5001 bits (210), Expect = 4.260e-16 Identity = 49/161 (30.43%), Postives = 73/161 (45.34%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIV------DESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWI------------IQSNYSENSFPEKSFQLVGNKCRNP 508 + C ++ + Y G + +G PC++W + + + D Y + NYCRNPT P GP+C V + + ++ CHIR C R C+ T GT+YLG LN T + + C W+ I+ N FP+ L N CRNP Sbjct: 518 LPECAVSESEKNYRGTQWTTYDGLPCVAWNVSLVRKTALVDGGY-----VKAKNYCRNPTKDPEGPYCFVRVDASENPTAVQKRSCHIRKCRNTR--CRVTGIGTDYLGTLNKTVSNRSCLKWVSKSSSSSPFDRAIKGNKENYVFPDGPPSLASNYCRNP 671 HSP 2 Score: 57.3806 bits (137), Expect = 2.765e-6 Identity = 33/91 (36.26%), Postives = 43/91 (47.25%), Query Frame = 2 Query: 89 CKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTS----IIETNYCRNPTNFPNGPWCI--VDESILEWEHCHIRSCIKE 343 C++T G EY GY NV+K+G PCL W + N+CRNPT P GPWC VD +++ E+C I C E Sbjct: 118 CRLTGPGVEYGGYVNVTKSGYPCLKWTEVTDALSSAAALADSKFPDHGGRKAARNWCRNPTGDPGGPWCYISVDGAVVP-EYCDIAGCDDE 207
BLAST of Prothrombin vs. Ensembl Cavefish
Match: mst1 (macrophage stimulating 1 [Source:NCBI gene;Acc:103025427]) HSP 1 Score: 75.0998 bits (183), Expect = 5.701e-16 Identity = 50/151 (33.11%), Postives = 73/151 (48.34%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--IKERNWCKD------TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517 I +G +Y G + + NGR C W ++Y ++ I Y D + ++ NYCRNP P PWC + +E E+C IR C I +R +G +Y G +N T +G C+ W Q + +P + LV N CRNPD S Sbjct: 193 INCNGEDYRGQVDHTVNGRECQRWDQQYPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPDVERENCDIRKCSGIPKRRLRPSYTTNCFRGRGEDYRGKVNETTSGIACQKWDAQFPHEHPFYPHTYECKGLVENYCRNPDGS 340 HSP 2 Score: 65.0846 bits (157), Expect = 2.027e-12 Identity = 46/145 (31.72%), Postives = 69/145 (47.59%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSN----YSENSFPEKSFQLVGNKCRNPDMS 517 I G +Y G + +++G+ C W ++ + D T+ +E NYCRNP GPWC + +E C+I C E C + + G +Y G ++ T G+ C+ W Q Y +P+KS L N CRNPD S Sbjct: 112 IVGKGEDYRGKVSKTQSGKTCQQWWSKFPH----DHRWTPSPTNGLELNYCRNPDGDRIGPWCYTTDPERRYESCNIPLCKDEV--CINCN-GEDYRGQVDHTVNGRECQRWDQQYPHQHIYQPEKYPDKS--LDDNYCRNPDAS 247 HSP 3 Score: 49.6766 bits (117), Expect = 3.374e-7 Identity = 30/107 (28.04%), Postives = 49/107 (45.79%), Query Frame = 2 Query: 26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER 346 + TAL LQ E E+C +G+ Y G ++ G C W ++ ++ + D + NYCRNP +GPWC + E+++C I+ C E+ Sbjct: 352 MRTALCLQIKRCADDI-EAEDC-YHENGKNYRGIVRKTRKGIICQKWSANTPHQTKINPKTHPDAN--LTENYCRNPDGDLHGPWCYTTDPKTEFDYCAIKQCAGEK 454
BLAST of Prothrombin vs. Ensembl Cavefish
Match: ENSAMXT00000018418.2 (plasminogen [Source:NCBI gene;Acc:103036400]) HSP 1 Score: 70.8626 bits (172), Expect = 1.906e-14 Identity = 43/139 (30.94%), Postives = 68/139 (48.92%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511 G +Y G + +K+G C W+ + ++ + + + +E+N+CRNP GPWC + WE+C I+ C +E C G Y G ++ T++G C+ W Q Y + FPEK + N CRNPD Sbjct: 116 GTDYRGTKSKTKSGTLCQRWESTFPHKPNITPRSH--PKADLESNFCRNPDGDKGGPWCYTTDPAKRWENCDIQDCTEECMHC----SGENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPEKYLEE--NYCRNPD 246 HSP 2 Score: 64.6994 bits (156), Expect = 2.281e-12 Identity = 46/153 (30.07%), Postives = 68/153 (44.44%), Query Frame = 2 Query: 86 NCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT---------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 NC T G Y G +V+++G+ C SW + ++ Y ++ NYCRNP N PWC + WE+C++ SC E + D G+ Y G + T +GK C+ W +S P+ + L N CRNPD Sbjct: 282 NC-TTGDGNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNY--PCKGLDQNYCRNPDNE-RKPWCYTTDPETRWEYCNVESCGNEPRPDEPVIAPNEDCYEDNGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNFPTADLRRNLCRNPD 430 HSP 3 Score: 62.003 bits (149), Expect = 2.543e-11 Identity = 42/144 (29.17%), Postives = 64/144 (44.44%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC-------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G + +++G C W + + S++ + +E NYCRNP P PWC + WE C + C + + N C D G Y G ++ T++GK C+ W Q + + P+ L N CRNPD Sbjct: 198 GENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPE--KYLEENYCRNPDGEPK-PWCFTESPAKRWEFCSVSRCTSPPPTIVPQLN-CTTGD-GNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNYPCKGLDQNYCRNPD 336 HSP 4 Score: 50.8322 bits (120), Expect = 1.413e-7 Identity = 42/166 (25.30%), Postives = 64/166 (38.55%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--------------------------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQ----SNYSENSFPEKSFQLVGNKCRNPD 511 +G Y G + +G+ C +W + + + T+ + N CRNP + PWC + + WE+C I C E CK T G Y G ++ T G C+ W S+++ + P+K L NKCRNPD Sbjct: 381 NGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNF--PTADLRRNLCRNP-DGDRAPWCYTTDPSVRWEYCRIERCGSTTVSLTPPPALKPVVPPTLLTQSVPSEFADCK-TGSGISYRGSVSKTVAGVTCQAWSASTPHLSSFTPQAHPDKG--LDSNKCRNPD 540
BLAST of Prothrombin vs. Ensembl Cavefish
Match: ENSAMXT00000018419.2 (plasminogen [Source:NCBI gene;Acc:103036400]) HSP 1 Score: 70.8626 bits (172), Expect = 1.919e-14 Identity = 43/139 (30.94%), Postives = 68/139 (48.92%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511 G +Y G + +K+G C W+ + ++ + + + +E+N+CRNP GPWC + WE+C I+ C +E C G Y G ++ T++G C+ W Q Y + FPEK + N CRNPD Sbjct: 105 GTDYRGTKSKTKSGTLCQRWESTFPHKPNITPRSH--PKADLESNFCRNPDGDKGGPWCYTTDPAKRWENCDIQDCTEECMHC----SGENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPEKYLEE--NYCRNPD 235 HSP 2 Score: 65.0846 bits (157), Expect = 2.168e-12 Identity = 46/153 (30.07%), Postives = 68/153 (44.44%), Query Frame = 2 Query: 86 NCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT---------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 NC T G Y G +V+++G+ C SW + ++ Y ++ NYCRNP N PWC + WE+C++ SC E + D G+ Y G + T +GK C+ W +S P+ + L N CRNPD Sbjct: 271 NC-TTGDGNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNY--PCKGLDQNYCRNPDNE-RKPWCYTTDPETRWEYCNVESCGNEPRPDEPVIAPNEDCYEDNGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNFPTADLRRNLCRNPD 419 HSP 3 Score: 61.6178 bits (148), Expect = 2.585e-11 Identity = 42/143 (29.37%), Postives = 63/143 (44.06%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 G Y G + +++G C W + + S++ + +E NYCRNP P PWC + WE C + C I + C D G Y G ++ T++GK C+ W Q + + P+ L N CRNPD Sbjct: 187 GENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPE--KYLEENYCRNPDGEPK-PWCFTESPAKRWEFCSVSRCTSPPPTIVPQLNCTTGD-GNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNYPCKGLDQNYCRNPD 325 HSP 4 Score: 50.8322 bits (120), Expect = 1.436e-7 Identity = 42/166 (25.30%), Postives = 64/166 (38.55%), Query Frame = 2 Query: 104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--------------------------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQ----SNYSENSFPEKSFQLVGNKCRNPD 511 +G Y G + +G+ C +W + + + T+ + N CRNP + PWC + + WE+C I C E CK T G Y G ++ T G C+ W S+++ + P+K L NKCRNPD Sbjct: 370 NGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNF--PTADLRRNLCRNP-DGDRAPWCYTTDPSVRWEYCRIERCGSTTVSLTPPPALKPVVPPTLLTQSVPSEFADCK-TGSGISYRGSVSKTVAGVTCQAWSASTPHLSSFTPQAHPDKG--LDSNKCRNPD 529
BLAST of Prothrombin vs. Ensembl Cavefish
Match: f2 (coagulation factor II, thrombin [Source:NCBI gene;Acc:103039180]) HSP 1 Score: 67.3958 bits (163), Expect = 2.639e-13 Identity = 48/162 (29.63%), Postives = 69/162 (42.59%), Query Frame = 2 Query: 83 ENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--------------IKERNWCKD---TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 ++C + T G Y G N++ +G+ C WK + + II + + N+CRNP P GPWC + + E C + C I+ER + K G Y GDL+ T G C W + + + E QLV N CRNPD Sbjct: 111 DHCYLNT-GEHYSGDVNLTISGKTCQYWKSNFPHRIIEINQTQLK----LPENFCRNPDKSPTGPWCFTSDPTVRREKCAVAKCGEPLQPVPTVKVGTIEER-YAKTKCIAGNGETYTGDLSVTLGGHTCLEWNLPKVKALSVGKEFKPDIQLVKNHCRNPD 266
BLAST of Prothrombin vs. Ensembl Cavefish
Match: hgfb (hepatocyte growth factor [Source:NCBI gene;Acc:103033838]) HSP 1 Score: 66.2402 bits (160), Expect = 7.278e-13 Identity = 43/147 (29.25%), Postives = 67/147 (45.58%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 +T +G Y G + +++GR C W + ++ + Y D ++ NYCRNP PWC + + WE+C I+ C + +T D G Y G + + G C+ W Q +S + P+K L N CRNPD Sbjct: 196 MTCNGESYRGPMDHTESGRECQRWDLDEPHKHLFHPKRYPDNG--LKDNYCRNPDGRQR-PWCFTTDPDVPWEYCSIKQCDSDNQSNIETTTTCFRDNGAGYRGTVAVPREGLTCQRWDAQFPHSHSYMPQKYRCKDLSENFCRNPD 339 HSP 2 Score: 56.9954 bits (136), Expect = 1.297e-9 Identity = 40/138 (28.99%), Postives = 59/138 (42.75%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKDTDKGTE--YLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511 G Y G V + G C W ++ + Y + N+CRNP + PWC + + W C +I C ++ KG+E Y G T++G +C PW S ++ S +L GN CRNPD Sbjct: 291 GAGYRGTVAVPREGLTCQRWDAQFPHSHSYMPQKY--RCKDLSENFCRNPDGR-DAPWCFTTDPNIPWAFCKNIPRCGAAATEPEECYKGSEETYRGKQMKTRSGILCAPWRDHSERNKREVVTLSEELEGNFCRNPD 425 HSP 3 Score: 53.9138 bits (128), Expect = 1.194e-8 Identity = 39/146 (26.71%), Postives = 63/146 (43.15%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 ++ C I T G Y G + ++ G C W +E + + N CRNP N GPWC + +++C+I C + T G Y G ++ T++G+ C+ W + + P++ L N CRNPD Sbjct: 109 VKECIIGT-GLNYKGKISKTETGEECQKWDLNTPHEHHFLPRRH--KKKDLRDNLCRNPDNSTTGPWCFTKNPNIRYQNCNIPQCSEVECM---TCNGESYRGPMDHTESGRECQRWDLDEPHKHLFHPKRYPDNGLKDNYCRNPD 248
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003778.1 (pep scaffold:Pmarinus_7.0:GL482904:4425:14035:-1 gene:ENSPMAG00000003419.1 transcript:ENSPMAT00000003778.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 71.633 bits (174), Expect = 2.191e-15 Identity = 42/160 (26.25%), Postives = 75/160 (46.88%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNW----------CKDTDK---------GTEYLGDLNFTKTGKICKPWIIQSNYSENSFP--EKSFQLVGNKCRNPD 511 +T +G +Y+G + +K+GR C W + +++ + ++E N+CRNP +GPWC + ++ E C + +C K+ N K + G +Y G +N T++G+ C+ W Q+ + P ++ L G CRNPD Sbjct: 108 MTGNGEQYIGNVSFTKSGRQCQLWTSNFPHQVRFK-PVDHPEKQLVE-NFCRNPDASQDGPWCYTRDPLVPREPCSVPTCDKDPNQHVPVSPRVTPTKPAPRPQGPCVPGAGEDYRGPVNVTRSGRHCQAWSAQTPHVSRYSPLTHRAAGLEGAACRNPD 265 HSP 2 Score: 46.595 bits (109), Expect = 9.536e-7 Identity = 28/68 (41.18%), Postives = 38/68 (55.88%), Query Frame = 2 Query: 326 RSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWII----QSNYSENSFPEKSFQLVGNKCRNPDMS 517 R C+K C T G +Y+G+++FTK+G+ C+ W Q + PEK QLV N CRNPD S Sbjct: 100 RGCLK--GLCM-TGNGEQYIGNVSFTKSGRQCQLWTSNFPHQVRFKPVDHPEK--QLVENFCRNPDAS 162
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: hgfb (hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GENE-041014-3]) HSP 1 Score: 61.6178 bits (148), Expect = 4.780e-12 Identity = 44/145 (30.34%), Postives = 62/145 (42.76%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCI-VDESILEWEHCHIRSCIKERNWCK-DTDKGTEYLGDLNFTKTGKICKPWIIQSN----YSENSFPEKSFQLVGNKCRNPD 511 + G +Y G N +K G PC W + + + Y S ++ NYCRNP PWC +D S+ HI C + + + GT Y G + T+ G C+ W S Y+ S P L G+ CRNPD Sbjct: 228 LEERGEDYRGRANHTKGGIPCQHWAAQQPHRHTYLEHNY--PCSGLDRNYCRNPDGREEAPWCFTLDPSVRRQLCSHIPRCAQPTAGSQCYSGSGTAYRGGVATTRHGLQCQAWNATSPHKPWYTPKSHPGAG--LEGHSCRNPD 368 HSP 2 Score: 60.8474 bits (146), Expect = 9.338e-12 Identity = 44/142 (30.99%), Postives = 68/142 (47.89%), Query Frame = 2 Query: 98 TTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIY--FDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511 T +G Y G N +++G PC +W ++ S Y FD +E N CRNP P PWC +S E C I C + C + +G Y G ++ T + + C+ W +Q ++ N P++ + L N CRNP+ Sbjct: 53 TGNGSGYRGDKNYTESGLPCQAWGDSEPHDSRYLPSFYPAFD----LEGNSCRNPAQEPGEPWCYTMDSNRRRERCGIPRCDEVP--CVEC-RGEHYRGLVDHTDSQRECQRWDLQHPHNHNYTPDRFPNAGLDDNYCRNPN 187 HSP 3 Score: 55.4546 bits (132), Expect = 8.221e-10 Identity = 44/159 (27.67%), Postives = 65/159 (40.88%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYL-NEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHI----------------RSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511 + G Y G + + + R C W ++ N D + ++ NYCRNP N PWC + WE+C I R C++ER G +Y G N TK G C+ W Q + +++ E ++ G N CRNPD Sbjct: 135 VECRGEHYRGLVDHTDSQRECQRWDLQHPHNHNYTPDRF---PNAGLDDNYCRNP-NGRMRPWCFTTDPHQPWEYCSIKPGCCASKATRPAMEGRPCLEER--------GEDYRGRANHTKGGIPCQHWAAQQPH-RHTYLEHNYPCSGLDRNYCRNPD 280 HSP 4 Score: 43.5134 bits (101), Expect = 8.728e-6 Identity = 25/107 (23.36%), Postives = 42/107 (39.25%), Query Frame = 2 Query: 38 LLLQSSFILSYFTEIENCKITTHGRE--------YVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 L S + I C T G + Y G +++G C +W ++ + + +E + CRNP P GPWC + L W++C + +C Sbjct: 289 FTLDPSVRRQLCSHIPRCAQPTAGSQCYSGSGTAYRGGVATTRHGLQCQAWNATSPHKPWYTPKSH--PGAGLEGHSCRNPDGDPWGPWCFTSDPHLPWDYCSVEAC 393
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001728.1 (pep scaffold:Pmarinus_7.0:GL477419:32233:56220:-1 gene:ENSPMAG00000001561.1 transcript:ENSPMAT00000001728.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 54.299 bits (129), Expect = 1.277e-9 Identity = 29/106 (27.36%), Postives = 51/106 (48.11%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLN 397 +++C T G Y G ++ +G C +W + + + + + +E NYCRNP + PNGPWCI + + WE+C ++ C + + T G+ N Sbjct: 8 VDHC-YTGSGTGYRGLQTLTASGHQCQTWASKTPHLHAYTPEGFPE--AGLENNYCRNPDSDPNGPWCITQDPNVLWEYCALQRCASGPSPTGAEQRATLSRGEKN 110 HSP 2 Score: 48.521 bits (114), Expect = 1.470e-7 Identity = 23/75 (30.67%), Postives = 34/75 (45.33%), Query Frame = 2 Query: 110 REYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 R Y G V+ G+ C +W + + + Y D + + YCRNP GPWC +S W++C I C Sbjct: 213 RGYRGAQAVTSGGKTCQAWASQSPHRHQFVPANYTD--ADLSLGYCRNPDGDLAGPWCYTTDSATRWQYCGIAHC 285
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005055.1 (pep scaffold:Pmarinus_7.0:GL479085:195887:200886:-1 gene:ENSPMAG00000004594.1 transcript:ENSPMAT00000005055.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 45.8246 bits (107), Expect = 5.724e-7 Identity = 31/132 (23.48%), Postives = 55/132 (41.67%), Query Frame = 2 Query: 8 LMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSW------KKEYLN-------------EIIMDDSIYFDTTSI----IETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 L N + TA+ S + +++C + G Y G + + +GR C W + +YL +++ S +F + +E N+CRNP + +GPWC + WE C + +C Sbjct: 15 LPVNSLMKTAIAKPGSSLYEKIVYLQDCMVGL-GISYRGTVSKTTSGRQCQFWSTNKPHRPKYLPFSRCEWTNARQHLSVMLSASHHFTPWTHPELGLEDNFCRNPDHGVSGPWCYTTDPAQRWEVCSVPAC 145
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO30193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1H4]) HSP 1 Score: 55.8398 bits (133), Expect = 4.942e-11 Identity = 26/82 (31.71%), Postives = 41/82 (50.00%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEII-MDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN 349 GR+Y G N + G C W +++ ++ M D + + + NYCRNP + PWC W++C IRSC K ++ Sbjct: 2 GRDYRGTMNFTAKGVTCQPWNEQWPHQHTEMADPLVAAREGLGKHNYCRNPGGRKHRPWCYTTLEKTRWQYCEIRSCRKTKS 83
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO43993 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX97]) HSP 1 Score: 53.9138 bits (128), Expect = 4.824e-9 Identity = 29/76 (38.16%), Postives = 40/76 (52.63%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334 G +Y+G NV+K G PCLSWK +D +Y + N+CRNP PWC VD++ +E+C I C Sbjct: 137 GEDYIGRLNVTKYGMPCLSWKS--------NDPVY-----KLSHNFCRNPRGQHEAPWCYVDKNT--YEYCVIPKC 197
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO39763 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S935]) HSP 1 Score: 50.0618 bits (118), Expect = 8.414e-9 Identity = 31/100 (31.00%), Postives = 46/100 (46.00%), Query Frame = 2 Query: 38 LLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNF-PNGPWCIVDESILEWEHCHIRSC 334 L + S I Y+ E G Y G NV+K+G C W + + + + Y T I +N+CRNP P+GPWC ++ WE+C + C Sbjct: 2 LSIPSPHIDCYYGE---------GVGYHGNINVTKSGISCQPWSSQCPHRHYHNSTQY--TELINASNFCRNPGGMGPDGPWCYTTNMMVRWEYCDVPKC 90
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO28926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T536]) HSP 1 Score: 48.9062 bits (115), Expect = 1.465e-8 Identity = 25/77 (32.47%), Postives = 39/77 (50.65%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNF-PNGPWCIVDESILEWEHCHIRSC 334 G Y G NV+K+G C W + + + + Y + I +N+CRNP P+GPWC ++ WE+C + C Sbjct: 7 GVGYHGNINVTKSGISCQPWSSQCPHHHYHNSTQYPEL--INASNFCRNPGGMGPDGPWCYTTNKLVRWEYCDVPKC 81
BLAST of Prothrombin vs. Ensembl Medaka
Match: f2 (prothrombin [Source:NCBI gene;Acc:101170246]) HSP 1 Score: 72.7886 bits (177), Expect = 3.661e-15 Identity = 48/159 (30.19%), Postives = 76/159 (47.80%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-------RNWCKDT----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511 +E ++ +G Y G +++K+GR C W + + I + + + SI++ N+CRNP GPWC + ++ E C + C ++ K T + G +Y GDL+ T G C W S ++ +K F QL GNKCRNPD Sbjct: 107 VEGHCVSGNGHNYNGNIHITKSGRVCQHWSHSFPHPIFREFNAS-EPNSILQENFCRNPDKRSEGPWCFTKDPSVQKETCRVPKCGEKFVPPTVAPEVVKTTICLPNYGVDYTGDLSVTLGGHTCIQW--SSPQAKALSKDKEFIPEVQLTGNKCRNPD 262
BLAST of Prothrombin vs. Ensembl Medaka
Match: f2 (prothrombin [Source:NCBI gene;Acc:101170246]) HSP 1 Score: 72.7886 bits (177), Expect = 3.661e-15 Identity = 48/159 (30.19%), Postives = 76/159 (47.80%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-------RNWCKDT----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511 +E ++ +G Y G +++K+GR C W + + I + + + SI++ N+CRNP GPWC + ++ E C + C ++ K T + G +Y GDL+ T G C W S ++ +K F QL GNKCRNPD Sbjct: 107 VEGHCVSGNGHNYNGNIHITKSGRVCQHWSHSFPHPIFREFNAS-EPNSILQENFCRNPDKRSEGPWCFTKDPSVQKETCRVPKCGEKFVPPTVAPEVVKTTICLPNYGVDYTGDLSVTLGGHTCIQW--SSPQAKALSKDKEFIPEVQLTGNKCRNPD 262
BLAST of Prothrombin vs. Ensembl Medaka
Match: f2 (prothrombin [Source:NCBI gene;Acc:101170246]) HSP 1 Score: 72.4034 bits (176), Expect = 5.173e-15 Identity = 47/154 (30.52%), Postives = 74/154 (48.05%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-------RNWCKDT----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511 ++ +G Y G +++K+GR C W + + I + + + SI++ N+CRNP GPWC + ++ E C + C ++ K T + G +Y GDL+ T G C W S ++ +K F QL GNKCRNPD Sbjct: 85 VSGNGHNYNGNIHITKSGRVCQHWSHSFPHPIFREFNAS-EPNSILQENFCRNPDKRSEGPWCFTKDPSVQKETCRVPKCGEKFVPPTVAPEVVKTTICLPNYGVDYTGDLSVTLGGHTCIQW--SSPQAKALSKDKEFIPEVQLTGNKCRNPD 235
BLAST of Prothrombin vs. Ensembl Medaka
Match: mst1 (hepatocyte growth factor-like protein [Source:NCBI gene;Acc:101168450]) HSP 1 Score: 68.5514 bits (166), Expect = 1.103e-13 Identity = 50/162 (30.86%), Postives = 80/162 (49.38%), Query Frame = 2 Query: 80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPDMS 517 I CK IT +G +Y G + + G+ C W +++ ++ I Y D + ++ NYCRNP P PWC + ++E E+C+I C +++R T +G +Y G +N T +G C+ W Q + E+ F ++ G N CRNPD S Sbjct: 182 IPQCKDEVCITCNGEDYRGQVDHTATGKECQRWDQQHPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPLVERENCNISKCPEVPVEKRQRSSFTTNCFRGRGEDYRGKVNETLSGIPCQRWNAQFPH-EHPFHPNIYECKGLEENYCRNPDGS 339 HSP 2 Score: 66.6254 bits (161), Expect = 5.683e-13 Identity = 50/146 (34.25%), Postives = 67/146 (45.89%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTS-IIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSN----YSENSFPEKSFQLVGNKCRNPDMS 517 I G +Y G +K+G C W ++ + D + T S +E NYCRNP GPWC + +E C+I C E T G +Y G ++ T TGK C+ W Q Y +P+KS L N CRNPD S Sbjct: 110 IVGKGEDYRGKVFTTKSGLNCQQWWSKFPH-----DHWWTPTASNGLELNYCRNPDGDNIGPWCYTTDPERRYESCNIPQCKDE---VCITCNGEDYRGQVDHTATGKECQRWDQQHPHQHIYQPEKYPDKS--LDDNYCRNPDAS 245 HSP 3 Score: 46.595 bits (109), Expect = 4.394e-6 Identity = 29/107 (27.10%), Postives = 48/107 (44.86%), Query Frame = 2 Query: 26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER 346 + TAL LQ E E+C +G+ Y G ++ G C W + ++ + + + NYCRNP +GPWC + E+++C I+ C E+ Sbjct: 351 MRTALCLQIKRCEDDI-EAEDC-YQENGKNYRGIVRKTRKGVTCQRWNVNTPHRTKINPLTHPEAN--LTENYCRNPDGDQHGPWCYTTDPKTEFDYCAIKQCAGEK 453
BLAST of Prothrombin vs. Ensembl Medaka
Match: hgfb (hepatocyte growth factor [Source:NCBI gene;Acc:101167035]) HSP 1 Score: 65.0846 bits (157), Expect = 1.647e-12 Identity = 45/147 (30.61%), Postives = 72/147 (48.98%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511 I +G +Y G + +++G+ C W + ++ + Y D ++ NYCRNP N + PWC + WE+C I+ C + N + T+ KG Y G ++ T TG C+ W Q ++ + PE + L N CRNPD Sbjct: 192 INCNGEDYRGPMDHTESGKECQRWDLDEPHKHLFHPKRYPDKG--LDDNYCRNP-NGRHRPWCFTTDPNTPWEYCTIKVCETPPDSNVVETTECFQGKGEGYRGVVDMTPTGLTCQRWDSQYPHNHSFIPEAYRCKDLRENYCRNPD 335 HSP 2 Score: 55.8398 bits (133), Expect = 2.535e-9 Identity = 44/150 (29.33%), Postives = 68/150 (45.33%), Query Frame = 2 Query: 80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEH--CHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSE----NSFPEKSFQLVGNKCRNPD 511 + C + T G+ Y G +V+ NG C +W +E S + NYCRNP N GPWC + + H C I C + C + + G +Y G ++ T++GK C+ W + + +P+K L N CRNP+ Sbjct: 103 VRECILGT-GQSYRGRRSVTVNGILCQAWASPIPHE--HKFMSKKFKKSDLRENYCRNPDNSTVGPWCFTTDPRPQLRHQECGIPQCSEVE--CINCN-GEDYRGPMDHTESGKECQRWDLDEPHKHLFHPKRYPDKG--LDDNYCRNPN 244 HSP 3 Score: 48.1358 bits (113), Expect = 1.228e-6 Identity = 25/81 (30.86%), Postives = 40/81 (49.38%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN 349 G Y G + +++ PC W+ E+ N + +E NYCRNP +GPWC + S + W++C I+ C +N Sbjct: 375 GENYRGQQSRTRSNLPCGPWR-EHSNSGERGMLMVG-----LEGNYCRNPDGDKHGPWCYTNNSAISWDYCSIKPCDASQN 449 HSP 4 Score: 48.1358 bits (113), Expect = 1.275e-6 Identity = 40/139 (28.78%), Postives = 57/139 (41.01%), Query Frame = 2 Query: 107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE---RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511 G Y G +++ G C W +Y + Y + NYCRNP + + PWC + + C +I C + N C ++ G Y G + T++ C PW SN E L GN CRNPD Sbjct: 287 GEGYRGVVDMTPTGLTCQRWDSQYPHNHSFIPEAY--RCKDLRENYCRNP-DGQDFPWCFTTDPRVRTMFCTNIPQCGTQNRLANECYES-LGENYRGQQSRTRSNLPCGPWREHSNSGERGM--LMVGLEGNYCRNPD 419
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026377.1 (SMESG000026377.1) HSP 1 Score: 360.147 bits (923), Expect = 1.418e-118 Identity = 168/169 (99.41%), Postives = 169/169 (100.00%), Query Frame = 2 Query: 11 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLN+IIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS Sbjct: 1 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNDIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 169
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026376.1 (SMESG000026376.1) HSP 1 Score: 236.113 bits (601), Expect = 1.479e-72 Identity = 104/169 (61.54%), Postives = 127/169 (75.15%), Query Frame = 2 Query: 11 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517 M + L+ LQ YF EIE CKI+THG EY+G N K+G+ C+ WK EY+N+I+MDD+ FD TSII NYCRNPTNFPNGPWCI+DE LEWEHC+I C+K+RNWCKD+DKGTEYLGD++ TK+GK+CKPWI ++ NSFPE + L GNKCRNPDMS Sbjct: 1 MLIVQLSAIFYLQCVIFAGYFEEIEKCKISTHGGEYMGKVNYGKSGQRCIFWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGPWCIIDEMTLEWEHCNIIKCVKDRNWCKDSDKGTEYLGDISHTKSGKMCKPWINFRKHTANSFPENNVHLAGNKCRNPDMS 169
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026355.1 (SMESG000026355.1) HSP 1 Score: 233.417 bits (594), Expect = 1.715e-71 Identity = 101/161 (62.73%), Postives = 133/161 (82.61%), Query Frame = 2 Query: 35 ALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517 AL L S SYFT+IENCKITTHGRE++G T+++KNG+ C++WK+E++N++ I +D+ S+I NYCRNPTNFPNGPWCI+DE+ L+WE+C+I+SCIK+RNWCKDT+ G EYLGD+N+TK+GK C PWI Q + ++SFPEK+ LVGNKCRNPDMS Sbjct: 9 ALPLLSRLTSSYFTDIENCKITTHGREFIGRTSITKNGQQCITWKEEFINKLQAGKIINYDSKSLIGNNYCRNPTNFPNGPWCIIDENTLKWEYCNIKSCIKDRNWCKDTENGREYLGDVNYTKSGKDCNPWINQRTHPKDSFPEKNLNLVGNKCRNPDMS 169
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026362.1 (SMESG000026362.1) HSP 1 Score: 228.024 bits (580), Expect = 1.224e-69 Identity = 102/169 (60.36%), Postives = 124/169 (73.37%), Query Frame = 2 Query: 11 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517 M + L+ LQ YF EIE C++TTHG EY+G N K+G+ C+ WK EY+N I+MDD+ F TSII NYCRNPTNFP GPWCI+DE LEWEHC+I CIK+RNWCKD+DKGTEYLGD++ TK+GK+CKPWI ++ NSFPE + L GNKCRNPDMS Sbjct: 1 MLIVQLSVIFSLQYVTFAGYFEEIEKCRMTTHGGEYMGKVNFGKSGQRCIFWKNEYVNHIVMDDTFVFVNTSIIGNNYCRNPTNFPRGPWCIIDEITLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKMCKPWINFRKHTANSFPENNVHLAGNKCRNPDMS 169
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026361.1 (SMESG000026361.1) HSP 1 Score: 211.075 bits (536), Expect = 1.237e-63 Identity = 90/141 (63.83%), Postives = 113/141 (80.14%), Query Frame = 2 Query: 95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517 +TTHGREY+G + K+G+ C+ WK EY+N+I+MDD+ FD TSII NYCRNPTNFPNG WCI+DE LEWEHC+I CIK+RNWCKD+DKGTEYLGD++ TK+GK+C+PWI + SFPE++ + GNKCRNPDMS Sbjct: 1 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMS 141 The following BLAST results are available for this feature:
BLAST of Prothrombin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Prothrombin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of Prothrombin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 2
BLAST of Prothrombin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Prothrombin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Prothrombin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Prothrombin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Prothrombin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Prothrombin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 4
BLAST of Prothrombin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of Prothrombin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of Prothrombin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Prothrombin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035288 ID=SMED30035288|Name=Prothrombin|organism=Schmidtea mediterranea sexual|type=transcript|length=517bpback to top protein sequence of SMED30035288-orf-1 >SMED30035288-orf-1 ID=SMED30035288-orf-1|Name=SMED30035288-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=172bp ANLMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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