Prothrombin

Overview
NameProthrombin
Smed IDSMED30035288
Length (bp)517
Neoblast Clusters

Zeng et. al., 2018




 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30035288

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 7

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
parapharyngeal regionSMED30035288h1SMcG0018613 SmedASXL_017423SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
parapharyngeal regionSMED30035288h1SMcG0018620 SmedASXL_017423SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30035288h1SMcG0018613 SmedASXL_019388SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30035288h1SMcG0018613 dd_Smed_v4_9120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035288h1SMcG0018613 dd_Smed_v4_9120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30035288h1SMcG0018613 dd_Smed_v4_9120_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
head regionSMED30035288h1SMcG0018613 dd_Smed_v6_9120_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Prothrombin vs. Ensembl Human
Match: MST1 (macrophage stimulating 1 [Source:HGNC Symbol;Acc:HGNC:7380])

HSP 1 Score: 77.411 bits (189), Expect = 2.152e-16
Identity = 48/145 (33.10%), Postives = 70/145 (48.28%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN-WCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQ--LVGNKCRNPDMS 517
            I  +G  Y G    +  G PC +W  ++ N     D  Y  T  + +E N+CRNP   P GPWC   +  + ++ C I+SC +    WC     G EY G ++ T++G+ C+ W +Q  +     P K     L  N CRNPD S
Sbjct:  125 IMNNGVGYRGTMATTVGGLPCQAWSHKFPN-----DHKYTPTLRNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWC----NGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGS 260          

HSP 2 Score: 63.929 bits (154), Expect = 8.678e-12
Identity = 46/159 (28.93%), Postives = 70/159 (44.03%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I++C+    +  +G EY G  + +++GR C  W  ++ ++   +   + D    ++ NYCRNP      PWC   +  +E E C +  C  E    ++         KG  Y G  N T  G  C+ W  Q  +     PEK     L  N CRNPD S
Sbjct:  197 IKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQG--LDDNYCRNPDG-SERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGS 352          

HSP 3 Score: 48.9062 bits (115), Expect = 1.219e-6
Identity = 39/139 (28.06%), Postives = 57/139 (41.01%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCH-IRSCIKE-RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN-SF-PEKSFQLVGNKCRNPD 511
            G  Y G  N +  G PC  W  +  ++       Y      +  N+CRNP      PWC      +    C+ IR C  + R        G +Y G ++ T+ G  C+ W  ++ +    +F  E   QL  N CRNPD
Sbjct:  302 GEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKY--ACKDLRENFCRNPDG-SEAPWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPD 437          
BLAST of Prothrombin vs. Ensembl Human
Match: HGF (hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893])

HSP 1 Score: 71.633 bits (174), Expect = 7.293e-15
Identity = 48/146 (32.88%), Postives = 66/146 (45.21%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            I NC I   GR Y G  +++K+G  C  W     +E     S Y      ++ NYCRNP     GPWC      + +E C I  C +       T  G  Y G ++ T++GKIC+ W  Q+ +     PE+        N CRNPD
Sbjct:  125 IRNC-IIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPD 264          
BLAST of Prothrombin vs. Ensembl Human
Match: PLG (plasminogen [Source:HGNC Symbol;Acc:HGNC:9071])

HSP 1 Score: 72.7886 bits (177), Expect = 7.384e-15
Identity = 51/166 (30.72%), Postives = 75/166 (45.18%), Query Frame = 2
Query:   20 IFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            I +   +L +    LS       CK T +G+ Y G  + +KNG  C  W     +      + +   +  +E NYCRNP N P GPWC   +    +++C I  C +E   C     G  Y G ++ T +G  C+ W  QS ++    P K  +  L  N CRNPD
Sbjct:   86 IRMRDVVLFEKKVYLS------ECK-TGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATH--PSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHC----SGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPD 238          

HSP 2 Score: 51.9878 bits (123), Expect = 1.004e-7
Identity = 40/142 (28.17%), Postives = 58/142 (40.85%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  + + +G  C +W  +  +      S + +    ++ NYCRNP      PWC   +    WE C I  C         T       G  Y G++  T +G  C+ W  Q+ ++ N  PE      L  N CRNPD
Sbjct:  190 GENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKN--LKKNYCRNPDRELR-PWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPD 328          

HSP 3 Score: 47.3654 bits (111), Expect = 4.746e-6
Identity = 32/116 (27.59%), Postives = 48/116 (41.38%), Query Frame = 2
Query:  230 IETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC---------------IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511
            +  NYCRNP +   GPWC   +  + WE+C+++ C               + +     + D     G  Y G    T TG  C+ W  Q  +  + F  ++    G   N CRNPD
Sbjct:  421 LTMNYCRNP-DADKGPWCFTTDPSVRWEYCNLKKCSGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPD 535          
BLAST of Prothrombin vs. Ensembl Human
Match: HGF (hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893])

HSP 1 Score: 71.633 bits (174), Expect = 1.690e-14
Identity = 49/148 (33.11%), Postives = 68/148 (45.95%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511
            I NC I   GR Y G  +++K+G  C  W     +E     S Y      ++ NYCRNP     GPWC      + +E C I  C +       T  G  Y G ++ T++GKIC+ W  Q+ +        +P+K F    N CRNPD
Sbjct:  125 IRNC-IIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFD--DNYCRNPD 264          

HSP 2 Score: 62.003 bits (149), Expect = 4.251e-11
Identity = 47/154 (30.52%), Postives = 66/154 (42.86%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-----------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517
            +T +G  Y G  + +++G+ C  W  +  +        Y D     + NYCRNP   P  PWC   +    WE+C I++C    N   DTD           +G  Y G +N    G  C+ W  Q  +  +  PE  K   L  N CRNPD S
Sbjct:  212 MTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKG--FDDNYCRNPDGQPR-PWCYTLDPHTRWEYCAIKTCAD--NTMNDTDVPLETTECIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGS 360          

HSP 3 Score: 52.373 bits (124), Expect = 7.940e-8
Identity = 27/98 (27.55%), Postives = 48/98 (48.98%), Query Frame = 2
Query:   62 LSYFTEIENCKIT-------THGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            + Y ++I NC ++        +G+ Y+G  + +++G  C  W K    E +     +    S +  NYCRNP +  +GPWC     ++ W++C I  C
Sbjct:  374 VGYCSQIPNCDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNM--EDLHRHIFWEPDASKLNENYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC 469          
BLAST of Prothrombin vs. Ensembl Human
Match: HGF (hepatocyte growth factor [Source:HGNC Symbol;Acc:HGNC:4893])

HSP 1 Score: 69.707 bits (169), Expect = 4.022e-14
Identity = 47/146 (32.19%), Postives = 67/146 (45.89%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            I NC I   GR Y G  +++K+G  C  W     + +I  +  Y      ++ NYCRNP     GPWC      + +E C I  C +       T  G  Y G ++ T++GKIC+ W  Q+ +     PE+        N CRNPD
Sbjct:  125 IRNC-IIGKGRSYKGTVSITKSGIKCQPW-----SSMIPHEHSY--RGKDLQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPD 259          
BLAST of Prothrombin vs. Ensembl Fly
Match: Nrk (gene:FBgn0020391 transcript:FBtr0087728)

HSP 1 Score: 56.6102 bits (135), Expect = 1.346e-9
Identity = 31/79 (39.24%), Postives = 43/79 (54.43%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIE-TNYCRNPTNFPNGPWC-IVDESILEWEHCHIRSC 334
            +GR Y+G  NVSK+G PC  W  +Y ++      ++     ++E  NYCRN       PWC  VDES+  W+HC I  C
Sbjct:  223 NGRFYMGTMNVSKSGIPCQRWDTQYPHKHFQPPLVFH---QLLEGENYCRNAGGEEPHPWCYTVDESV-RWQHCDIPMC 297          
BLAST of Prothrombin vs. Ensembl Fly
Match: Ror (gene:FBgn0010407 transcript:FBtr0079978)

HSP 1 Score: 53.5286 bits (127), Expect = 1.541e-8
Identity = 33/79 (41.77%), Postives = 39/79 (49.37%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVD---ESILEWEHCHIRSC 334
            G  Y G  NVS +G+PCL W    + EI        D   +I  NYCRNP +  N PWC VD   E I+E   C I  C
Sbjct:  242 GSTYRGVANVSASGKPCLRWS-WLMKEI-------SDFPELIGQNYCRNPGSVENSPWCFVDSSRERIIEL--CDIPKC 310          
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: plg (plasminogen [Source:ZFIN;Acc:ZDB-GENE-030131-1411])

HSP 1 Score: 73.1738 bits (178), Expect = 3.561e-15
Identity = 47/166 (28.31%), Postives = 77/166 (46.39%), Query Frame = 2
Query:   26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511
            ++ AL  +  ++L     I        G +Y G  + +K+G+ C  W+  + +   +    Y    + +E+N+CRNP     GPWC   +    WEHC+I+ C +E   C     G  Y G ++ T +G  C+ W  Q      Y  ++ P+K  +   N CRNPD
Sbjct:   96 MSAALYEKKEYLLECVNGI--------GMDYRGTKSKTKSGKTCQRWEGTFPHVPNITPRAY--PKADLESNFCRNPDGDKGGPWCYTTDPEKRWEHCNIQDCTEECMQC----SGENYRGKISTTVSGFTCQRWDSQQPQNHGYLPSALPDKYLEE--NYCRNPD 245          

HSP 2 Score: 66.2402 bits (160), Expect = 9.660e-13
Identity = 46/142 (32.39%), Postives = 59/142 (41.55%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER-----NWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  + + +G  C  W  +         S   D    +E NYCRNP   P  PWC        WE C I  C  E           + +G+ Y G ++ T TGK C+ W  QS +  +  PE      L GN CRNPD
Sbjct:  197 GENYRGKISTTVSGFTCQRWDSQQPQNHGYLPSALPD--KYLEENYCRNPDGEPR-PWCFTTSPSKRWEACAIPRCTTEPPTIVPELTCASGEGSSYRGTISVTITGKTCQQWTSQSPHKHSRSPENYPCKGLDGNYCRNPD 335          

HSP 3 Score: 58.5362 bits (140), Expect = 3.703e-10
Identity = 42/147 (28.57%), Postives = 63/147 (42.86%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  +V+  G+ C  W  +  ++       Y      ++ NYCRNP N    PWC   +    WE+C + SC          I +   C + D G+ Y G ++ T +GK C+ W     +  +  P+      L  N CRNPD
Sbjct:  287 GSSYRGTISVTITGKTCQQWTSQSPHKHSRSPENY--PCKGLDGNYCRNPDNE-RSPWCYTTDPETRWEYCSVPSCGDQPRPEEPVIPQGEECYEGD-GSSYRGVMSETISGKKCQFWTSMEPHRHSKTPQNFPKADLRRNLCRNPD 429          
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: mst1 (macrophage stimulating 1 [Source:ZFIN;Acc:ZDB-GENE-020806-3])

HSP 1 Score: 71.2478 bits (173), Expect = 1.601e-14
Identity = 52/161 (32.30%), Postives = 77/161 (47.83%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC---IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPDMS 517
            I  CK    IT +G +Y G  + + +G+ C  W +++ ++ I     Y D +  ++ NYCRNP   P  PWC   +  +E E C I  C    K R     T      +G +Y G +N T +G  C+ W  Q  +    FP K+++  G   N CRNPD S
Sbjct:  184 IPQCKDEVCITCNGEDYRGQVDHTVSGKECQRWDQQFPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPTMERESCDISKCPEFPKRRLRSSYTTNCFRGRGEDYRGKVNETTSGIPCQRWDAQKPHEHPFFP-KTYECKGLEENYCRNPDGS 340          

HSP 2 Score: 68.9366 bits (167), Expect = 9.011e-14
Identity = 48/145 (33.10%), Postives = 67/145 (46.21%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPW----IIQSNYSENSFPEKSFQLVGNKCRNPDMS 517
            I   G +Y G  + + +GR C  W  ++ +    D       T+ +E NYCRNP     GPWC   +    +E C+I  C  E      T  G +Y G ++ T +GK C+ W      Q  Y    +P+KS  L  N CRNPD S
Sbjct:  112 IVGKGEDYRGKVSTTTSGRTCQQWWSKFPH----DHRWTPSATNGLELNYCRNPDGDRIGPWCYTTDPERRYESCNIPQCKDEVCI---TCNGEDYRGQVDHTVSGKECQRWDQQFPHQHIYQPEKYPDKS--LDDNYCRNPDAS 247          

HSP 3 Score: 51.6026 bits (122), Expect = 1.016e-7
Identity = 41/141 (29.08%), Postives = 60/141 (42.55%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIK--ERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQ--LVGNKCRNPD 511
             G +Y G  N + +G PC  W  +  +E       Y      +E NYCRNP +    PWC      +    C  I+ C    E   C + + G  Y G +  T+ G +C+ W I + +     P+   +  L  N CRNPD
Sbjct:  289 RGEDYRGKVNETTSGIPCQRWDAQKPHEHPFFPKTY--ECKGLEENYCRNP-DGSEAPWCFTSLPEMRTALCLQIKRCADDIEAEDCYN-EIGKNYRGVVRKTRKGILCQKWSINTPHKTKINPKTHPEANLTDNYCRNPD 425          

HSP 4 Score: 46.595 bits (109), Expect = 5.735e-6
Identity = 29/107 (27.10%), Postives = 48/107 (44.86%), Query Frame = 2
Query:   26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER 346
            + TAL LQ         E E+C     G+ Y G    ++ G  C  W     ++  ++   + +    +  NYCRNP    +GPWC   +   E+++C I+ C  E+
Sbjct:  352 MRTALCLQIKRCADDI-EAEDC-YNEIGKNYRGVVRKTRKGILCQKWSINTPHKTKINPKTHPEAN--LTDNYCRNPDGDHHGPWCYTSDPKTEFDYCAIKQCAGEK 454          
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: hgfb (hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GENE-041014-3])

HSP 1 Score: 63.1586 bits (152), Expect = 1.038e-11
Identity = 42/147 (28.57%), Postives = 65/147 (44.22%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPD 511
            +T +G  Y G  + +++GR C  W  E  ++ I     Y D    ++ NYCRNP      PWC   +    WE+C+I+ C  + +   +        +G  Y G +  T  G  C+ W  Q  +  +  P+      L  N CRNPD
Sbjct:  191 MTCNGESYRGPLDHTESGRECQRWDLEEPHKHIFHPKRYPDKG--LKDNYCRNPDGRQR-PWCFTTDPSTPWEYCNIKQCDSDNSGDVENTTTCFRGRGEGYRGTIGITPDGVTCQRWDAQFPHRHSYTPQNYHCKDLRENYCRNPD 334          

HSP 2 Score: 60.4622 bits (145), Expect = 7.733e-11
Identity = 43/145 (29.66%), Postives = 65/145 (44.83%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNE--IIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSE----NSFPEKSFQLVGNKCRNPD 511
            I  +G  Y G  +V+K+G  C  W  +  +E   +     + D    +  N CRNP N   GPWC   +  L  + C I  C +       T  G  Y G L+ T++G+ C+ W ++  +        +P+K   L  N CRNPD
Sbjct:  108 IIGNGLNYKGKRSVTKSGVQCQLWNSKMPHEHNFLPQRHKHRD----LRDNLCRNPDNTTTGPWCFTTDPKLRHQDCSIPQCSEVECM---TCNGESYRGPLDHTESGRECQRWDLEEPHKHIFHPKRYPDKG--LKDNYCRNPD 243          

HSP 3 Score: 46.595 bits (109), Expect = 5.649e-6
Identity = 40/150 (26.67%), Postives = 61/150 (40.67%), Query Frame = 2
Query:   77 EIENCKITTHGRE--YVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKDTDKGTE--YLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511
            ++EN      GR   Y G   ++ +G  C  W  ++ +        Y      +  NYCRNP    + PWC   +  +    C +I  C  +     +  KG    Y G  + T++G  C PW   S  +E      + +  GN CRNPD
Sbjct:  274 DVENTTTCFRGRGEGYRGTIGITPDGVTCQRWDAQFPHRHSYTPQNYH--CKDLRENYCRNPDGR-HLPWCFTTDPTVPIAFCTNIPRCGVKPPEPGECYKGIGDMYNGHRSKTRSGIPCAPWKDHSESNERDVNLLTTEQAGNFCRNPD 420          
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: hgfa (hepatocyte growth factor a [Source:ZFIN;Acc:ZDB-GENE-041014-2])

HSP 1 Score: 61.2326 bits (147), Expect = 4.064e-11
Identity = 42/141 (29.79%), Postives = 62/141 (43.97%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPD 511
            I   G  Y G  + +K G  C SW     +E     + +    S +  N+CRNP N PNGPWC  + +    + C +  C      C   + G  Y G ++ T++GK C+ W  Q  +     P +     L  N CRNP+
Sbjct:  114 IIGSGVNYKGRRSFTKTGITCQSWNMSVPHEHNFKPTRH--KKSDLRQNFCRNPDNDPNGPWCFTELTETRHQDCGLPQCSDVE--CMKCN-GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKGLDDNFCRNPN 249          

HSP 2 Score: 53.1434 bits (126), Expect = 2.491e-8
Identity = 39/145 (26.90%), Postives = 62/145 (42.76%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517
            G  Y G  + +++G+ C  W  +  ++       +      ++ N+CRNP N    PWC   +    WE+C+I  C  + +   +        +G  Y G +N T  G  C+ W   S +  +  P   K   L  N CRNPD S
Sbjct:  201 GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKG--LDDNFCRNPNNDVR-PWCYTMDKNTPWEYCNISVCDSDSDVEVEVTSSCFRGQGEGYRGTVNVTPAGVTCQRWDALSPHIHSYTPHNYKCKDLRENYCRNPDGS 342          

HSP 3 Score: 49.2914 bits (116), Expect = 6.159e-7
Identity = 41/149 (27.52%), Postives = 63/149 (42.28%), Query Frame = 2
Query:   74 TEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKD--TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511
             E+ +      G  Y G  NV+  G  C  W  + L+  I   + +      +  NYCRNP +    PWC   ++ +    C +I  C  E +   +   D G  Y G+L+ T++G  C  W   +   +    + S  L  N CRNPD
Sbjct:  281 VEVTSSCFRGQGEGYRGTVNVTPAGVTCQRW--DALSPHIHSYTPHNYKCKDLRENYCRNP-DGSEIPWCFTTDAKVRKAFCTNIPRCESESSDSTECYEDNGESYRGNLSKTRSGIPCGLWSDHTFRRDTRSAKASAGLELNLCRNPD 426          

HSP 4 Score: 47.7506 bits (112), Expect = 2.210e-6
Identity = 22/76 (28.95%), Postives = 36/76 (47.37%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            G  Y G  + +++G PC  W     +     D+     ++ +E N CRNP    +GPWC    S + W++C +  C
Sbjct:  380 GESYRGNLSKTRSGIPCGLWS----DHTFRRDTRSAKASAGLELNLCRNPDRDKHGPWCYTSNSSIPWDYCGLERC 451          
BLAST of Prothrombin vs. Ensembl Zebrafish
Match: hgfa (hepatocyte growth factor a [Source:ZFIN;Acc:ZDB-GENE-041014-2])

HSP 1 Score: 61.2326 bits (147), Expect = 4.291e-11
Identity = 42/141 (29.79%), Postives = 62/141 (43.97%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPD 511
            I   G  Y G  + +K G  C SW     +E     + +    S +  N+CRNP N PNGPWC  + +    + C +  C      C   + G  Y G ++ T++GK C+ W  Q  +     P +     L  N CRNP+
Sbjct:  114 IIGSGVNYKGRRSFTKTGITCQSWNMSVPHEHNFKPTRH--KKSDLRQNFCRNPDNDPNGPWCFTELTETRHQDCGLPQCSDVE--CMKCN-GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKGLDDNFCRNPN 249          

HSP 2 Score: 53.1434 bits (126), Expect = 2.579e-8
Identity = 39/145 (26.90%), Postives = 62/145 (42.76%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517
            G  Y G  + +++G+ C  W  +  ++       +      ++ N+CRNP N    PWC   +    WE+C+I  C  + +   +        +G  Y G +N T  G  C+ W   S +  +  P   K   L  N CRNPD S
Sbjct:  201 GETYRGPMDHTESGKECQRWDSQKPHKHTYQPHRHVGKG--LDDNFCRNPNNDVR-PWCYTMDKNTPWEYCNISVCDSDSDVEVEVTSSCFRGQGEGYRGTVNVTPAGVTCQRWDALSPHIHSYTPHNYKCKDLRENYCRNPDGS 342          

HSP 3 Score: 49.2914 bits (116), Expect = 6.378e-7
Identity = 41/149 (27.52%), Postives = 63/149 (42.28%), Query Frame = 2
Query:   74 TEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKD--TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511
             E+ +      G  Y G  NV+  G  C  W  + L+  I   + +      +  NYCRNP +    PWC   ++ +    C +I  C  E +   +   D G  Y G+L+ T++G  C  W   +   +    + S  L  N CRNPD
Sbjct:  281 VEVTSSCFRGQGEGYRGTVNVTPAGVTCQRW--DALSPHIHSYTPHNYKCKDLRENYCRNP-DGSEIPWCFTTDAKVRKAFCTNIPRCESESSDSTECYEDNGESYRGNLSKTRSGIPCGLWSDHTFRRDTRSAKASAGLELNLCRNPD 426          

HSP 4 Score: 47.7506 bits (112), Expect = 2.005e-6
Identity = 26/101 (25.74%), Postives = 44/101 (43.56%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKT 409
            G  Y G  + +++G PC  W     +     D+     ++ +E N CRNP    +GPWC    S + W++C +  C   +  C    K T  +G +   + 
Sbjct:  380 GESYRGNLSKTRSGIPCGLWS----DHTFRRDTRSAKASAGLELNLCRNPDRDKHGPWCYTSNSSIPWDYCGLERCGGPKPSCF-IHKTTRIVGGMRVQRA 475          
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056])

HSP 1 Score: 77.7962 bits (190), Expect = 1.409e-16
Identity = 52/159 (32.70%), Postives = 84/159 (52.83%), Query Frame = 2
Query:   47 QSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            Q S +L Y+  I +C +  +G  Y G  + +KNGR C  W+ ++ ++     + + +    +E NYCRNP + P G WC   +  +  ++C I+ C  E   C  T  G +Y G ++ T++GK C+ W +Q+ ++    PEK     L  N CRNPD S
Sbjct:   56 QCSDLLDYY--IRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 204          

HSP 2 Score: 61.2326 bits (147), Expect = 7.323e-11
Identity = 49/166 (29.52%), Postives = 76/166 (45.78%), Query Frame = 2
Query:   59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCI-KERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            I   +  I+ C+    +T +G +Y G  + +++G+ C  W  +  +        Y D +  ++ NYCRNP +    PWC   +  +E E C I  C  K+R    +T      ++G  Y G  N T +G  C+ W  Q+ +     PEK     L  N CRNPD S
Sbjct:  134 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCTEKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 296          
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056])

HSP 1 Score: 75.0998 bits (183), Expect = 1.018e-15
Identity = 51/165 (30.91%), Postives = 85/165 (51.52%), Query Frame = 2
Query:   38 LLLQSSFILSYFTE---IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            +LLQ +     + +   I +C +  +G  Y G  + +KNGR C  W+ ++ ++     + + +    +E NYCRNP + P G WC   +  +  ++C I+ C  E   C  T  G +Y G ++ T++GK C+ W +Q+ ++    PEK     L  N CRNPD S
Sbjct:  100 VLLQRNVQYDLYQKKDYIRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 256          

HSP 2 Score: 65.4698 bits (158), Expect = 2.561e-12
Identity = 49/165 (29.70%), Postives = 76/165 (46.06%), Query Frame = 2
Query:   59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            I   +  I+ C+    +T +G +Y G  + +++G+ C  W  +  +        Y D +  ++ NYCRNP +    PWC   +  +E E C I  C K+R    +T      ++G  Y G  N T +G  C+ W  Q+ +     PEK     L  N CRNPD S
Sbjct:  186 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCKKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 347          

HSP 3 Score: 47.7506 bits (112), Expect = 2.762e-6
Identity = 40/140 (28.57%), Postives = 58/140 (41.43%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE--RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF-QLVGNKCRNPD 511
             G  Y G  N + +G PC  W  +  +        Y      ++ NYCRNP +    PWC      +   +C  I+ C  +     C   + G  Y G ++ T+ G  C+ W  + N  E S  +     L GN CRNPD
Sbjct:  296 RGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKY--PCKGLDENYCRNP-DGSEAPWCFTTLPGMRMAYCFQIKRCTDDVVEPGCYHGN-GELYNGRVSKTRKGITCRKWEEKRNDLELSLDQPYLVPLEGNYCRNPD 431          
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056])

HSP 1 Score: 75.0998 bits (183), Expect = 1.085e-15
Identity = 51/165 (30.91%), Postives = 85/165 (51.52%), Query Frame = 2
Query:   38 LLLQSSFILSYFTE---IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            +LLQ +     + +   I +C +  +G  Y G  + +KNGR C  W+ ++ ++     + + +    +E NYCRNP + P G WC   +  +  ++C I+ C  E   C  T  G +Y G ++ T++GK C+ W +Q+ ++    PEK     L  N CRNPD S
Sbjct:  100 VLLQRNVQYDLYQKKDYIRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 256          

HSP 2 Score: 65.0846 bits (157), Expect = 3.006e-12
Identity = 49/165 (29.70%), Postives = 76/165 (46.06%), Query Frame = 2
Query:   59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            I   +  I+ C+    +T +G +Y G  + +++G+ C  W  +  +        Y D +  ++ NYCRNP +    PWC   +  +E E C I  C K+R    +T      ++G  Y G  N T +G  C+ W  Q+ +     PEK     L  N CRNPD S
Sbjct:  186 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCKKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 347          

HSP 3 Score: 47.7506 bits (112), Expect = 3.116e-6
Identity = 40/140 (28.57%), Postives = 58/140 (41.43%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE--RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF-QLVGNKCRNPD 511
             G  Y G  N + +G PC  W  +  +        Y      ++ NYCRNP +    PWC      +   +C  I+ C  +     C   + G  Y G ++ T+ G  C+ W  + N  E S  +     L GN CRNPD
Sbjct:  296 RGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKY--PCKGLDENYCRNP-DGSEAPWCFTTLPGMRMAYCFQIKRCTDDVVEPGCYHGN-GELYNGRVSKTRKGITCRKWEEKRNDLELSLDQPYLVPLEGNYCRNPD 431          
BLAST of Prothrombin vs. Ensembl Xenopus
Match: MST1 (macrophage stimulating 1 [Source:NCBI gene;Acc:100494056])

HSP 1 Score: 75.0998 bits (183), Expect = 1.205e-15
Identity = 51/165 (30.91%), Postives = 85/165 (51.52%), Query Frame = 2
Query:   38 LLLQSSFILSYFTE---IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            +LLQ +     + +   I +C +  +G  Y G  + +KNGR C  W+ ++ ++     + + +    +E NYCRNP + P G WC   +  +  ++C I+ C  E   C  T  G +Y G ++ T++GK C+ W +Q+ ++    PEK     L  N CRNPD S
Sbjct:   87 VLLQRNVQYDLYQKKDYIRDC-VVGNGITYRGTVSKTKNGRTCQHWRLKFPHDHKFSPTHWPE----LEENYCRNPDSDPEGLWCYTTDKNIRHQYCGIKKC--EDAVCL-TCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKSLDDNYCRNPDSS 243          

HSP 2 Score: 61.2326 bits (147), Expect = 7.552e-11
Identity = 49/166 (29.52%), Postives = 76/166 (45.78%), Query Frame = 2
Query:   59 ILSYFTEIENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCI-KERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPDMS 517
            I   +  I+ C+    +T +G +Y G  + +++G+ C  W  +  +        Y D +  ++ NYCRNP +    PWC   +  +E E C I  C  K+R    +T      ++G  Y G  N T +G  C+ W  Q+ +     PEK     L  N CRNPD S
Sbjct:  173 IRHQYCGIKKCEDAVCLTCNGEDYRGSVDRTESGKECQRWDLQAPHTHPYKPEKYPDKS--LDDNYCRNPDSSER-PWCYTTDPNVEKEFCQITKCTEKQRLPNVETTSTCFKERGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKYPCKGLDENYCRNPDGS 335          

HSP 3 Score: 47.7506 bits (112), Expect = 3.113e-6
Identity = 40/140 (28.57%), Postives = 58/140 (41.43%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE--RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF-QLVGNKCRNPD 511
             G  Y G  N + +G PC  W  +  +        Y      ++ NYCRNP +    PWC      +   +C  I+ C  +     C   + G  Y G ++ T+ G  C+ W  + N  E S  +     L GN CRNPD
Sbjct:  284 RGEGYRGKANTTTSGIPCQRWDSQTPHVHRFLPEKY--PCKGLDENYCRNP-DGSEAPWCFTTLPGMRMAYCFQIKRCTDDVVEPGCYHGN-GELYNGRVSKTRKGITCRKWEEKRNDLELSLDQPYLVPLEGNYCRNPD 419          
BLAST of Prothrombin vs. Ensembl Xenopus
Match: ENSXETT00000037773.1 (plasminogen [Source:NCBI gene;Acc:100496227])

HSP 1 Score: 73.9442 bits (180), Expect = 3.077e-15
Identity = 53/174 (30.46%), Postives = 83/174 (47.70%), Query Frame = 2
Query:    2 ANLMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511
            A L+F  FL    +    F   Y  E     IT  G++Y G  + + +G+ C +W   + +        YF    + E N+CRNP N  NGPWC   +  + +E+C+I  C ++   C     G  Y G ++ T +G  C+ W  Q+     YS ++ P+K+ +   N CRNPD
Sbjct:    6 ATLLFQTFLKRCKI-HMYFFTVYLKEC----ITGKGKDYRGTESKTHSGKTCQNWTGSFPHV-----PKYFPNAGL-EGNFCRNPDNDLNGPWCYTTDFSVRFEYCNIPQCEEDCMHC----SGENYRGRISKTASGTECQNWDSQTPHSHGYSPSNIPDKNLER--NYCRNPD 162          

HSP 2 Score: 65.855 bits (159), Expect = 1.683e-12
Identity = 45/151 (29.80%), Postives = 68/151 (45.03%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDK----------GTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            ++  G  Y G   V+ +G+ C  W  +  ++ I     Y      +E NYCRNP +  + PWC   +S   WE+C+I SC         T+           G++Y G    T +GK C+PW  Q+ +     P+   +  L  N CRNPD
Sbjct:  200 LSGKGENYSGNIAVTASGKTCQEWSLQVPHKHIRTPDNY--PCKNLEKNYCRNP-DGESMPWCYTTDSETRWEYCNIPSCDAPTVNAAPTNPSTILECYDGNGSKYRGTAYITVSGKKCQPWNSQTPHKHTKMPDNFPNAGLEQNYCRNPD 347          

HSP 3 Score: 62.7734 bits (151), Expect = 2.232e-11
Identity = 43/142 (30.28%), Postives = 59/142 (41.55%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKD-----TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  + + +G  C +W  +  +      S   D    +E NYCRNP   P  PWC        WEHC+I  C              + KG  Y G++  T +GK C+ W +Q  +     P+      L  N CRNPD
Sbjct:  114 GENYRGRISKTASGTECQNWDSQTPHSHGYSPSNIPDKN--LERNYCRNPDGEPR-PWCFTTNPNKRWEHCNIPRCTTNPPTSAPGVQCLSGKGENYSGNIAVTASGKTCQEWSLQVPHKHIRTPDNYPCKNLEKNYCRNPD 252          

HSP 4 Score: 59.3066 bits (142), Expect = 3.434e-10
Identity = 44/155 (28.39%), Postives = 70/155 (45.16%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNE-IIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIK----ERNWCKD-----------TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511
            +G +Y G   ++ +G+ C  W  +  ++   M D+      + +E NYCRNP +   GPWC   ++ + WE+C ++ C +    E+   +              KG +Y G  + T  G IC+ W  QS     SF   +    G   N CRNPD
Sbjct:  298 NGSKYRGTAYITVSGKKCQPWNSQTPHKHTKMPDNF---PNAGLEQNYCRNP-DEDKGPWCYTTDASVRWEYCSLKKCSELPSTEQRPVQTTKITTITTNCIVSKGEDYRGIKSTTLNGHICQAWSSQSPQEHASFTPITHPQSGLESNYCRNPD 448          

HSP 5 Score: 53.1434 bits (126), Expect = 4.514e-8
Identity = 31/84 (36.90%), Postives = 42/84 (50.00%), Query Frame = 2
Query:   86 NCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIV-DESILEWEHCHIRSC 334
            NC I + G +Y G  + + NG  C +W  +   E      I     S +E+NYCRNP    NGPWC V     ++WE+C I  C
Sbjct:  393 NC-IVSKGEDYRGIKSTTLNGHICQAWSSQSPQEHASFTPITH-PQSGLESNYCRNPDGDINGPWCFVTTPGTVKWEYCDIPRC 474          
BLAST of Prothrombin vs. Ensembl Mouse
Match: Mst1 (macrophage stimulating 1 (hepatocyte growth factor-like) [Source:MGI Symbol;Acc:MGI:96080])

HSP 1 Score: 77.411 bits (189), Expect = 1.225e-16
Identity = 47/144 (32.64%), Postives = 70/144 (48.61%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I  +G  Y G    +  G PC +W + + N     D  Y  T  + +E N+CRNP   P GPWC      + ++ C I++C   R        G +Y G+++ T++G+ C+ W +Q  +S    PEK     L  N CRNPD S
Sbjct:  111 IMDNGVSYRGTVARTAGGLPCQAWSRRFPN-----DHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTC---REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGS 246          

HSP 2 Score: 69.707 bits (169), Expect = 5.518e-14
Identity = 50/159 (31.45%), Postives = 73/159 (45.91%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC---IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I+ C+    +  +G +Y G  +V+++GR C  W  ++ +        + D    ++ NYCRNP      PWC   +  +E E C + SC    + RN  K  +    KG +Y G  N T  G  C+ W  QS +     PEK     L  N CRNPD S
Sbjct:  183 IKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKD--LKDNYCRNPDG-SERPWCYTTDPNVEREFCDLPSCGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGS 338          
BLAST of Prothrombin vs. Ensembl Mouse
Match: Mst1 (macrophage stimulating 1 (hepatocyte growth factor-like) [Source:MGI Symbol;Acc:MGI:96080])

HSP 1 Score: 77.411 bits (189), Expect = 1.228e-16
Identity = 47/144 (32.64%), Postives = 70/144 (48.61%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I  +G  Y G    +  G PC +W + + N     D  Y  T  + +E N+CRNP   P GPWC      + ++ C I++C   R        G +Y G+++ T++G+ C+ W +Q  +S    PEK     L  N CRNPD S
Sbjct:  111 IMDNGVSYRGTVARTAGGLPCQAWSRRFPN-----DHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTC---REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGS 246          

HSP 2 Score: 66.2402 bits (160), Expect = 8.923e-13
Identity = 50/168 (29.76%), Postives = 73/168 (43.45%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC------------IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I+ C+    +  +G +Y G  +V+++GR C  W  ++ +        + D    ++ NYCRNP      PWC   +  +E E C + SC             + RN  K  +    KG +Y G  N T  G  C+ W  QS +     PEK     L  N CRNPD S
Sbjct:  183 IKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKD--LKDNYCRNPDG-SERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGS 347          
BLAST of Prothrombin vs. Ensembl Mouse
Match: Plg (plasminogen [Source:MGI Symbol;Acc:MGI:97620])

HSP 1 Score: 70.8626 bits (172), Expect = 2.545e-14
Identity = 48/170 (28.24%), Postives = 78/170 (45.88%), Query Frame = 2
Query:    8 LMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            +  N   ++ + ++   +      +  CK T  G  Y G  + +K+G  C  W   + +  + + S        +E NYCRNP N   GPWC   +    +++C+I  C +E  +C     G +Y G ++ T +G  C+ W  QS ++    P K  S  L  N CRNPD
Sbjct:   76 MAENSKTSSIIRMRDVILFEKRVYLSECK-TGIGNGYRGTMSRTKSGVACQKWGATFPH--VPNYSPSTHPNEGLEENYCRNPDNDEQGPWCYTTDPDKRYDYCNIPECEEECMYC----SGEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKFPSKNLKMNYCRNPD 238          

HSP 2 Score: 61.6178 bits (148), Expect = 3.735e-11
Identity = 41/159 (25.79%), Postives = 68/159 (42.77%), Query Frame = 2
Query:  101 THGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC-------------IKERNWCKDTD------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511
            + G+ Y G ++ +  G+ C SW   + +        + D    +E NYCRNP +   GPWC   +  + WE+C+++ C              +E +   D++       G +Y G    T  G  C+ W  Q  +  + F  ++    G   N CRNPD
Sbjct:  380 SDGQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPENFPDAG--LEMNYCRNP-DGDKGPWCYTTDPSVRWEYCNLKRCSETGGSVVELPTVSQEPSGPSDSETDCMYGNGKDYRGKTAVTAAGTPCQGWAAQEPHRHSIFTPQTNPRAGLEKNYCRNPD 535          

HSP 3 Score: 59.3066 bits (142), Expect = 2.361e-10
Identity = 41/142 (28.87%), Postives = 62/142 (43.66%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G +Y G  + + +G  C +W  +  +      + +   +  ++ NYCRNP   P  PWC   +    WE+C I  C         T      +G  Y G ++ T +GK C+ W  Q+ +  N  PE      L  N CRNPD
Sbjct:  190 GEKYEGKISKTMSGLDCQAWDSQSPHAHGYIPAKF--PSKNLKMNYCRNPDGEPR-PWCFTTDPTKRWEYCDIPRCTTPPPPPSPTYQCLKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENFPCKNLEENYCRNPD 328          

HSP 4 Score: 58.151 bits (139), Expect = 6.075e-10
Identity = 47/162 (29.01%), Postives = 67/162 (41.36%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN------------------WCKDTDKGTEYLGDLNFTKTGKICKPWII-----QSNYSENSFPEKSFQLVGNKCRNPD 511
            +   G  Y G  +V+ +G+ C  W ++  +        +      +E NYCRNP +    PWC   +S L WE+C I SC    +                   C  +D G  Y G  + T TGK C+ W        S   EN FP+   ++  N CRNPD
Sbjct:  276 LKGRGENYRGTVSVTVSGKTCQRWSEQTPHRHNRTPENF--PCKNLEENYCRNP-DGETAPWCYTTDSQLRWEYCEIPSCESSASPDQSDSSVPPEEQTPVVQECYQSD-GQSYRGTSSTTITGKKCQSWAAMFPHRHSKTPEN-FPDAGLEM--NYCRNPD 430          

HSP 5 Score: 48.1358 bits (113), Expect = 1.559e-6
Identity = 27/81 (33.33%), Postives = 39/81 (48.15%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTT---SIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCI 337
            +G++Y G T V+  G PC  W  +  +      SI+   T   + +E NYCRNP    NGPWC        +++C I  C 
Sbjct:  485 NGKDYRGKTAVTAAGTPCQGWAAQEPHR----HSIFTPQTNPRAGLEKNYCRNPDGDVNGPWCYTTNPRKLYDYCDIPLCA 561          
BLAST of Prothrombin vs. Ensembl Mouse
Match: Hgf (hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079])

HSP 1 Score: 68.1662 bits (165), Expect = 2.316e-13
Identity = 47/148 (31.76%), Postives = 66/148 (44.59%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511
            I NC I   G  Y G  +++K+G  C  W     +E     S Y      ++ NYCRNP     GPWC      + +E C I  C +       T  G  Y G ++ T++GK C+ W  Q+ +        +P+K F    N CRNPD
Sbjct:  126 IRNC-IIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFD--DNYCRNPD 265          

HSP 2 Score: 57.7658 bits (138), Expect = 9.089e-10
Identity = 44/152 (28.95%), Postives = 67/152 (44.08%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517
            +T +G  Y G  + +++G+ C  W ++  +        Y D     + NYCRNP   P  PWC   +    WE+C I++C    + E +   +T      +G  Y G  N    G  C+ W  Q  +  +  PE  K   L  N CRNPD +
Sbjct:  213 MTCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKG--FDDNYCRNPDGKPR-PWCYTLDPDTPWEYCAIKTCAHSAVNETDVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDGA 361          

HSP 3 Score: 51.9878 bits (123), Expect = 8.201e-8
Identity = 26/98 (26.53%), Postives = 48/98 (48.98%), Query Frame = 2
Query:   62 LSYFTEIENCKITT-------HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            + Y ++I  C +++       +G+ Y+G  + +++G  C  W K    E +     +    S +  NYCRNP +  +GPWC     ++ W++C I  C
Sbjct:  375 VGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNM--EDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC 470          
BLAST of Prothrombin vs. Ensembl Mouse
Match: Hgf (hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079])

HSP 1 Score: 68.1662 bits (165), Expect = 2.316e-13
Identity = 47/148 (31.76%), Postives = 66/148 (44.59%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511
            I NC I   G  Y G  +++K+G  C  W     +E     S Y      ++ NYCRNP     GPWC      + +E C I  C +       T  G  Y G ++ T++GK C+ W  Q+ +        +P+K F    N CRNPD
Sbjct:  126 IRNC-IIGKGGSYKGTVSITKSGIKCQPWNSMIPHEHSFLPSSYRGKD--LQENYCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCSEVECM---TCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKGFD--DNYCRNPD 265          

HSP 2 Score: 57.7658 bits (138), Expect = 9.089e-10
Identity = 44/152 (28.95%), Postives = 67/152 (44.08%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517
            +T +G  Y G  + +++G+ C  W ++  +        Y D     + NYCRNP   P  PWC   +    WE+C I++C    + E +   +T      +G  Y G  N    G  C+ W  Q  +  +  PE  K   L  N CRNPD +
Sbjct:  213 MTCNGESYRGPMDHTESGKTCQRWDQQTPHRHKFLPERYPDKG--FDDNYCRNPDGKPR-PWCYTLDPDTPWEYCAIKTCAHSAVNETDVPMETTECIQGQGEGYRGTSNTIWNGIPCQRWDSQYPHKHDITPENFKCKDLRENYCRNPDGA 361          

HSP 3 Score: 51.9878 bits (123), Expect = 8.201e-8
Identity = 26/98 (26.53%), Postives = 48/98 (48.98%), Query Frame = 2
Query:   62 LSYFTEIENCKITT-------HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            + Y ++I  C +++       +G+ Y+G  + +++G  C  W K    E +     +    S +  NYCRNP +  +GPWC     ++ W++C I  C
Sbjct:  375 VGYCSQIPKCDVSSGQDCYRGNGKNYMGNLSKTRSGLTCSMWDKNM--EDLHRHIFWEPDASKLNKNYCRNPDDDAHGPWCYTGNPLIPWDYCPISRC 470          
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|P26928|HGFL_MOUSE (Hepatocyte growth factor-like protein OS=Mus musculus OX=10090 GN=Mst1 PE=2 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 8.588e-16
Identity = 47/144 (32.64%), Postives = 70/144 (48.61%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I  +G  Y G    +  G PC +W + + N     D  Y  T  + +E N+CRNP   P GPWC      + ++ C I++C   R        G +Y G+++ T++G+ C+ W +Q  +S    PEK     L  N CRNPD S
Sbjct:  111 IMDNGVSYRGTVARTAGGLPCQAWSRRFPN-----DHKYTPTPKNGLEENFCRNPDGDPRGPWCYTTNRSVRFQSCGIKTC---REAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKDLKDNYCRNPDGS 246          

HSP 2 Score: 66.2402 bits (160), Expect = 6.242e-12
Identity = 50/168 (29.76%), Postives = 73/168 (43.45%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC------------IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I+ C+    +  +G +Y G  +V+++GR C  W  ++ +        + D    ++ NYCRNP      PWC   +  +E E C + SC             + RN  K  +    KG +Y G  N T  G  C+ W  QS +     PEK     L  N CRNPD S
Sbjct:  183 IKTCREAVCVLCNGEDYRGEVDVTESGRECQRWDLQHPHSHPFQPEKFLDKD--LKDNYCRNPDG-SERPWCYTTDPNVEREFCDLPSCGPNLPPTVKGSKSQRRNKGKALNCFRGKGEDYRGTTNTTSAGVPCQRWDAQSPHQHRFVPEKYACKDLRENFCRNPDGS 347          
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|P26927|HGFL_HUMAN (Hepatocyte growth factor-like protein OS=Homo sapiens OX=9606 GN=MST1 PE=1 SV=2)

HSP 1 Score: 77.411 bits (189), Expect = 1.030e-15
Identity = 48/145 (33.10%), Postives = 70/145 (48.28%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDT-TSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN-WCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQ--LVGNKCRNPDMS 517
            I  +G  Y G    +  G PC +W  ++ N     D  Y  T  + +E N+CRNP   P GPWC   +  + ++ C I+SC +    WC     G EY G ++ T++G+ C+ W +Q  +     P K     L  N CRNPD S
Sbjct:  111 IMNNGVGYRGTMATTVGGLPCQAWSHKFPN-----DHKYTPTLRNGLEENFCRNPDGDPGGPWCYTTDPAVRFQSCGIKSCREAACVWC----NGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGS 246          

HSP 2 Score: 63.929 bits (154), Expect = 4.153e-11
Identity = 46/159 (28.93%), Postives = 70/159 (44.03%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF--QLVGNKCRNPDMS 517
            I++C+    +  +G EY G  + +++GR C  W  ++ ++   +   + D    ++ NYCRNP      PWC   +  +E E C +  C  E    ++         KG  Y G  N T  G  C+ W  Q  +     PEK     L  N CRNPD S
Sbjct:  183 IKSCREAACVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQG--LDDNYCRNPDG-SERPWCYTTDPQIEREFCDLPRCGSEAQPRQEATTVSCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGS 338          

HSP 3 Score: 48.9062 bits (115), Expect = 5.835e-6
Identity = 39/139 (28.06%), Postives = 57/139 (41.01%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCH-IRSCIKE-RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN-SF-PEKSFQLVGNKCRNPD 511
            G  Y G  N +  G PC  W  +  ++       Y      +  N+CRNP      PWC      +    C+ IR C  + R        G +Y G ++ T+ G  C+ W  ++ +    +F  E   QL  N CRNPD
Sbjct:  288 GEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKY--ACKDLRENFCRNPDG-SEAPWCFTLRPGMRAAFCYQIRRCTDDVRPQDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPD 423          
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|Q29485|PLMN_ERIEU (Plasminogen OS=Erinaceus europaeus OX=9365 GN=PLG PE=2 SV=1)

HSP 1 Score: 75.0998 bits (183), Expect = 6.290e-15
Identity = 49/160 (30.63%), Postives = 74/160 (46.25%), Query Frame = 2
Query:   38 LLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            L ++   +      +  CK+  +G+ Y G  + +K G  C  W  E  ++     S   + +  ++ NYCRNP N P GPWC   +  + +E+C I  C  E   C     G  Y+G ++ T +G  C+PW  Q  +     P K  S  L  N CRNPD
Sbjct:   86 LRMRDVILFEKKMYLSECKVG-NGKYYRGTVSKTKTGLTCQKWSAETPHKPRF--SPDENPSEGLDQNYCRNPDNDPKGPWCYTMDPEVRYEYCEIIQCEDECMHC----SGQNYVGKISRTMSGLECQPWDSQIPHPHGFIPSKFPSKNLKMNYCRNPD 238          

HSP 2 Score: 61.6178 bits (148), Expect = 2.306e-10
Identity = 44/160 (27.50%), Postives = 62/160 (38.75%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDK-------------------GTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            +  +G  Y G   V+ +G  C  W ++  +        Y      ++ NYCRNP   P  PWC    S + WE C I  C+   +  + +D                    G  Y G  + T TGK C+PW     +  +  PE      L  N CRNPD
Sbjct:  276 LMGNGEHYQGNVAVTVSGLTCQRWGEQSPHRHDRTPENY--PCKNLDENYCRNPDGEP-APWCFTTNSSVRWEFCKIPDCVSSASETEHSDAPVIVPPEQTPVVQECYQGNGQTYRGTSSTTITGKKCQPWTSMRPHRHSKTPENYPDADLTMNYCRNPD 432          

HSP 3 Score: 56.225 bits (134), Expect = 2.010e-8
Identity = 42/142 (29.58%), Postives = 60/142 (42.25%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G+ YVG  + + +G  C  W  +  +      S +   +  ++ NYCRNP   P  PWC   +    WE+C I  C         T       G  Y G++  T +G  C+ W  QS +  +  PE      L  N CRNPD
Sbjct:  190 GQNYVGKISRTMSGLECQPWDSQIPHPHGFIPSKF--PSKNLKMNYCRNPDGEPR-PWCFTMDRNKRWEYCDIPRCTTPPPPSGPTYQCLMGNGEHYQGNVAVTVSGLTCQRWGEQSPHRHDRTPENYPCKNLDENYCRNPD 328          

HSP 4 Score: 53.5286 bits (127), Expect = 1.527e-7
Identity = 41/156 (26.28%), Postives = 61/156 (39.10%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------------------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSF-PEKSFQ--LVGNKCRNPD 511
            G+ Y G ++ +  G+ C  W     +        Y D    +  NYCRNP +   GPWC   +  + WE C+++ C        ++                  D G  Y G    T  G  C+ W  Q  +  + F PE + +  L  N CRNPD
Sbjct:  384 GQTYRGTSSTTITGKKCQPWTSMRPHRHSKTPENYPDAD--LTMNYCRNP-DGDKGPWCYTTDPSVRWEFCNLKKCSGTEMSATNSSPVQVSSASESSEQDCIIDNGKGYRGTKATTGAGTPCQAWAAQEPHRHSIFTPETNPRADLQENYCRNPD 536          
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|O18783|PLMN_MACEU (Plasminogen OS=Macropus eugenii OX=9315 GN=PLG PE=2 SV=1)

HSP 1 Score: 72.7886 bits (177), Expect = 3.281e-14
Identity = 49/146 (33.56%), Postives = 69/146 (47.26%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            + +CK + +GR Y G  + +K+G  C  W     +      S Y D    +E NYCRNP +   GPWC      + +E+C +  C  E   C     G  Y G ++ T++G  C+PW  Q  +S    P K  S  L  N CRNPD
Sbjct:  100 LSDCK-SGNGRNYRGTLSKTKSGITCQKWSDLSPHVPNYAPSKYPDAG--LEKNYCRNPDDDVKGPWCYTTNPDIRYEYCDVPECEDECMHC----SGENYRGTISKTESGIECQPWDSQEPHSHEYIPSKFPSKDLKENYCRNPD 238          

HSP 2 Score: 58.151 bits (139), Expect = 4.368e-9
Identity = 45/145 (31.03%), Postives = 63/145 (43.45%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSW--KKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKD-----TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511
            G  Y G  + +++G  C  W  ++ + +E I      F +  + E NYCRNP   P  PWC        WE C+I  C                +G  Y G +  TK+G  C+ W  Q+ +  N  PE +F   G   N CRNPD
Sbjct:  190 GENYRGTISKTESGIECQPWDSQEPHSHEYIPSK---FPSKDLKE-NYCRNPDGEPR-PWCFTSNPEKRWEFCNIPRCSSPPPPPGPMLQCLKGRGENYRGKIAVTKSGHTCQRWNKQTPHKHNRTPE-NFPCRGLDENYCRNPD 328          

HSP 3 Score: 51.6026 bits (122), Expect = 7.528e-7
Identity = 40/152 (26.32%), Postives = 60/152 (39.47%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTD-----------KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            +   G  Y G   V+K+G  C  W K+  ++       +      ++ NYCRNP      PWC      +  E+C I SC          +           KG  Y G  + T +GK C+ W   + +     P+   +  L+ N CRNPD
Sbjct:  276 LKGRGENYRGKIAVTKSGHTCQRWNKQTPHKHNRTPENF--PCRGLDENYCRNPDGELE-PWCYTTNPDVRQEYCAIPSCGTSSPHTDRVEQSPVIQECYEGKGENYRGTTSTTISGKKCQAWSSMTPHQHKKTPDNFPNADLIRNYCRNPD 424          
BLAST of Prothrombin vs. UniProt/SwissProt
Match: sp|P00747|PLMN_HUMAN (Plasminogen OS=Homo sapiens OX=9606 GN=PLG PE=1 SV=2)

HSP 1 Score: 72.7886 bits (177), Expect = 3.546e-14
Identity = 51/166 (30.72%), Postives = 75/166 (45.18%), Query Frame = 2
Query:   20 IFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            I +   +L +    LS       CK T +G+ Y G  + +KNG  C  W     +      + +   +  +E NYCRNP N P GPWC   +    +++C I  C +E   C     G  Y G ++ T +G  C+ W  QS ++    P K  +  L  N CRNPD
Sbjct:   86 IRMRDVVLFEKKVYLS------ECK-TGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATH--PSEGLEENYCRNPDNDPQGPWCYTTDPEKRYDYCDILECEEECMHC----SGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNPD 238          

HSP 2 Score: 51.9878 bits (123), Expect = 4.821e-7
Identity = 40/142 (28.17%), Postives = 58/142 (40.85%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  + + +G  C +W  +  +      S + +    ++ NYCRNP      PWC   +    WE C I  C         T       G  Y G++  T +G  C+ W  Q+ ++ N  PE      L  N CRNPD
Sbjct:  190 GENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKN--LKKNYCRNPDRELR-PWCFTTDPNKRWELCDIPRCTTPPPSSGPTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPD 328          
BLAST of Prothrombin vs. TrEMBL
Match: R7VDJ1 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_224866 PE=4 SV=1)

HSP 1 Score: 88.5817 bits (218), Expect = 2.342e-18
Identity = 51/164 (31.10%), Postives = 83/164 (50.61%), Query Frame = 2
Query:   38 LLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE-KSFQLVG------NKCRNP 508
            LLL     L+   E   CK++  G EY G  + + +GR C  W  +  +   +DD+ +      +  N+CRNP+N P GPWC+  +  + W++C +  C      C+D   G  Y G L++T  G IC+ W +Q  +    + + K+++L+G      N CRNP
Sbjct:   13 LLLLPWIPLAVAAE---CKLSQRGVEYSGTLSTTISGRTCQRWDVQTPHAHNVDDAHF--PNDDLAHNHCRNPSNDPGGPWCLTTDPAIRWQYCRVLFCSSCDRGCRDDKGGHFYKGLLSYTPDGVICQRWDVQDPHLHLGYSKLKNWKLLGDIGDNDNYCRNP 171          
BLAST of Prothrombin vs. TrEMBL
Match: R7USY4 (Uncharacterized protein OS=Capitella teleta OX=283909 GN=CAPTEDRAFT_223208 PE=4 SV=1)

HSP 1 Score: 86.2705 bits (212), Expect = 6.970e-17
Identity = 46/150 (30.67%), Postives = 69/150 (46.00%), Query Frame = 2
Query:   89 CKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER-----NWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSEN----SFPEKSFQLVGNKCRNPD 511
            C+ T  G++YVG   ++ +G  C  W ++Y  E  M  + + +       NYCRNP   P GPWC      + WE+C I  C         + CK    G  Y G ++ +++G+ C+ W  Q  +        FPE +     N CRNPD
Sbjct:  150 CRNTQLGKDYVGQKQITTSGNECQRWDRQYPQEHSMQGNWFSEGDLHSAVNYCRNPDGEPGGPWCYTTNPDVRWEYCEIPFCPGADFNDIYSECKKDTLGRTYRGLVSTSRSGRECQYWTRQYPHEHRMNGKGFPEGNMAAAANFCRNPD 299          

HSP 2 Score: 65.855 bits (159), Expect = 1.740e-9
Identity = 29/82 (35.37%), Postives = 42/82 (51.22%), Query Frame = 2
Query:   89 CKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            CK  T GR Y G  + S++GR C  W ++Y +E  M+   + +       N+CRNP   P GPWC   +    WE+C +  C
Sbjct:  243 CKKDTLGRTYRGLVSTSRSGRECQYWTRQYPHEHRMNGKGFPEGNMAAAANFCRNPDGEPEGPWCYTTDPETRWEYCVVDLC 324          
BLAST of Prothrombin vs. TrEMBL
Match: H3CM77 (Prothrombin OS=Tetraodon nigroviridis OX=99883 PE=3 SV=1)

HSP 1 Score: 85.8853 bits (211), Expect = 3.409e-16
Identity = 52/154 (33.77%), Postives = 79/154 (51.30%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-----------RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511
            I+  G  Y G  N+SK+GR C  WK  + + II + +      SI+E N+CRNP N  +GPWC   +  ++ E C + +C +            ++    ++ GT+Y GDL+ T  G  C  W   S  ++    +K F    +L+GNKCRNPD
Sbjct:  112 ISGTGANYAGNVNISKSGRQCQHWKHNFPHPIIREFNAS-KPGSILEENFCRNPNNSADGPWCFTTDPTVQKETCRVPTCGEAFVPPTLAPTHIKSTACLSNYGTDYTGDLDVTAGGHPCLQW--SSPEAKALSKDKEFIPEVRLLGNKCRNPD 262          
BLAST of Prothrombin vs. TrEMBL
Match: A0A2U9AVB1 (Putative prothrombin isoform 3 OS=Scophthalmus maximus OX=52904 GN=SMAX5B_002120 PE=3 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 4.001e-16
Identity = 51/159 (32.08%), Postives = 79/159 (49.69%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE---RNWCKDTDK--------GTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511
            IE   I   G  Y G  N++++GRPC  W+  + + I+ + +I  +  S ++ N+CRNP N P GPWC   +  ++ E C + +C ++        + D+        G +Y+GDL  T  G  C  W +      +  +   PE    LVGNKCRNPD
Sbjct:  107 IEGQCIFGKGVNYDGNVNITQSGRPCQYWRHSFPHPIMREFNIS-EPNSNLDENFCRNPDNRPEGPWCFTQDPTVQKEACRVPTCGEDFVPSTVAPEPDQTEECLPNYGVDYVGDLAVTLGGHTCLQWSLPKLTALSVDKEFMPE--VPLVGNKCRNPD 262          
BLAST of Prothrombin vs. TrEMBL
Match: A0A5E4MF17 (Immunoglobulin-like fold,Kringle,Kringle-like fold,Thrombospondin type-1 (TSP1) repeat,Kringle OS=Cinara cedri OX=506608 GN=CINCED_3A022495 PE=4 SV=1)

HSP 1 Score: 85.5001 bits (210), Expect = 4.260e-16
Identity = 49/161 (30.43%), Postives = 73/161 (45.34%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIV------DESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWI------------IQSNYSENSFPEKSFQLVGNKCRNP 508
            +  C ++   + Y G    + +G PC++W    + +  + D  Y     +   NYCRNPT  P GP+C V      + + ++   CHIR C   R  C+ T  GT+YLG LN T + + C  W+            I+ N     FP+    L  N CRNP
Sbjct:  518 LPECAVSESEKNYRGTQWTTYDGLPCVAWNVSLVRKTALVDGGY-----VKAKNYCRNPTKDPEGPYCFVRVDASENPTAVQKRSCHIRKCRNTR--CRVTGIGTDYLGTLNKTVSNRSCLKWVSKSSSSSPFDRAIKGNKENYVFPDGPPSLASNYCRNP 671          

HSP 2 Score: 57.3806 bits (137), Expect = 2.765e-6
Identity = 33/91 (36.26%), Postives = 43/91 (47.25%), Query Frame = 2
Query:   89 CKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTS----IIETNYCRNPTNFPNGPWCI--VDESILEWEHCHIRSCIKE 343
            C++T  G EY GY NV+K+G PCL W +                          N+CRNPT  P GPWC   VD +++  E+C I  C  E
Sbjct:  118 CRLTGPGVEYGGYVNVTKSGYPCLKWTEVTDALSSAAALADSKFPDHGGRKAARNWCRNPTGDPGGPWCYISVDGAVVP-EYCDIAGCDDE 207          
BLAST of Prothrombin vs. Ensembl Cavefish
Match: mst1 (macrophage stimulating 1 [Source:NCBI gene;Acc:103025427])

HSP 1 Score: 75.0998 bits (183), Expect = 5.701e-16
Identity = 50/151 (33.11%), Postives = 73/151 (48.34%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--IKERNWCKD------TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPDMS 517
            I  +G +Y G  + + NGR C  W ++Y ++ I     Y D +  ++ NYCRNP   P  PWC   +  +E E+C IR C  I +R             +G +Y G +N T +G  C+ W  Q  +    +P   +   LV N CRNPD S
Sbjct:  193 INCNGEDYRGQVDHTVNGRECQRWDQQYPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPDVERENCDIRKCSGIPKRRLRPSYTTNCFRGRGEDYRGKVNETTSGIACQKWDAQFPHEHPFYPHTYECKGLVENYCRNPDGS 340          

HSP 2 Score: 65.0846 bits (157), Expect = 2.027e-12
Identity = 46/145 (31.72%), Postives = 69/145 (47.59%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSN----YSENSFPEKSFQLVGNKCRNPDMS 517
            I   G +Y G  + +++G+ C  W  ++ +    D       T+ +E NYCRNP     GPWC   +    +E C+I  C  E   C + + G +Y G ++ T  G+ C+ W  Q      Y    +P+KS  L  N CRNPD S
Sbjct:  112 IVGKGEDYRGKVSKTQSGKTCQQWWSKFPH----DHRWTPSPTNGLELNYCRNPDGDRIGPWCYTTDPERRYESCNIPLCKDEV--CINCN-GEDYRGQVDHTVNGRECQRWDQQYPHQHIYQPEKYPDKS--LDDNYCRNPDAS 247          

HSP 3 Score: 49.6766 bits (117), Expect = 3.374e-7
Identity = 30/107 (28.04%), Postives = 49/107 (45.79%), Query Frame = 2
Query:   26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER 346
            + TAL LQ         E E+C    +G+ Y G    ++ G  C  W     ++  ++   + D    +  NYCRNP    +GPWC   +   E+++C I+ C  E+
Sbjct:  352 MRTALCLQIKRCADDI-EAEDC-YHENGKNYRGIVRKTRKGIICQKWSANTPHQTKINPKTHPDAN--LTENYCRNPDGDLHGPWCYTTDPKTEFDYCAIKQCAGEK 454          
BLAST of Prothrombin vs. Ensembl Cavefish
Match: ENSAMXT00000018418.2 (plasminogen [Source:NCBI gene;Acc:103036400])

HSP 1 Score: 70.8626 bits (172), Expect = 1.906e-14
Identity = 43/139 (30.94%), Postives = 68/139 (48.92%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511
            G +Y G  + +K+G  C  W+  + ++  +    +    + +E+N+CRNP     GPWC   +    WE+C I+ C +E   C     G  Y G ++ T++G  C+ W  Q      Y  + FPEK  +   N CRNPD
Sbjct:  116 GTDYRGTKSKTKSGTLCQRWESTFPHKPNITPRSH--PKADLESNFCRNPDGDKGGPWCYTTDPAKRWENCDIQDCTEECMHC----SGENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPEKYLEE--NYCRNPD 246          

HSP 2 Score: 64.6994 bits (156), Expect = 2.281e-12
Identity = 46/153 (30.07%), Postives = 68/153 (44.44%), Query Frame = 2
Query:   86 NCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT---------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            NC  T  G  Y G  +V+++G+ C SW  +  ++       Y      ++ NYCRNP N    PWC   +    WE+C++ SC  E    +           D G+ Y G +  T +GK C+ W     +S    P+   +  L  N CRNPD
Sbjct:  282 NC-TTGDGNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNY--PCKGLDQNYCRNPDNE-RKPWCYTTDPETRWEYCNVESCGNEPRPDEPVIAPNEDCYEDNGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNFPTADLRRNLCRNPD 430          

HSP 3 Score: 62.003 bits (149), Expect = 2.543e-11
Identity = 42/144 (29.17%), Postives = 64/144 (44.44%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC-------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  + +++G  C  W  +  +      S++ +    +E NYCRNP   P  PWC  +     WE C +  C       + + N C   D G  Y G ++ T++GK C+ W  Q  +  +  P+      L  N CRNPD
Sbjct:  198 GENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPE--KYLEENYCRNPDGEPK-PWCFTESPAKRWEFCSVSRCTSPPPTIVPQLN-CTTGD-GNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNYPCKGLDQNYCRNPD 336          

HSP 4 Score: 50.8322 bits (120), Expect = 1.413e-7
Identity = 42/166 (25.30%), Postives = 64/166 (38.55%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--------------------------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQ----SNYSENSFPEKSFQLVGNKCRNPD 511
            +G  Y G    + +G+ C +W     +  +     +   T+ +  N CRNP +    PWC   +  + WE+C I  C                            E   CK T  G  Y G ++ T  G  C+ W       S+++  + P+K   L  NKCRNPD
Sbjct:  381 NGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNF--PTADLRRNLCRNP-DGDRAPWCYTTDPSVRWEYCRIERCGSTTVSLTPPPALKPVVPPTLLTQSVPSEFADCK-TGSGISYRGSVSKTVAGVTCQAWSASTPHLSSFTPQAHPDKG--LDSNKCRNPD 540          
BLAST of Prothrombin vs. Ensembl Cavefish
Match: ENSAMXT00000018419.2 (plasminogen [Source:NCBI gene;Acc:103036400])

HSP 1 Score: 70.8626 bits (172), Expect = 1.919e-14
Identity = 43/139 (30.94%), Postives = 68/139 (48.92%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQS----NYSENSFPEKSFQLVGNKCRNPD 511
            G +Y G  + +K+G  C  W+  + ++  +    +    + +E+N+CRNP     GPWC   +    WE+C I+ C +E   C     G  Y G ++ T++G  C+ W  Q      Y  + FPEK  +   N CRNPD
Sbjct:  105 GTDYRGTKSKTKSGTLCQRWESTFPHKPNITPRSH--PKADLESNFCRNPDGDKGGPWCYTTDPAKRWENCDIQDCTEECMHC----SGENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPEKYLEE--NYCRNPD 235          

HSP 2 Score: 65.0846 bits (157), Expect = 2.168e-12
Identity = 46/153 (30.07%), Postives = 68/153 (44.44%), Query Frame = 2
Query:   86 NCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT---------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            NC  T  G  Y G  +V+++G+ C SW  +  ++       Y      ++ NYCRNP N    PWC   +    WE+C++ SC  E    +           D G+ Y G +  T +GK C+ W     +S    P+   +  L  N CRNPD
Sbjct:  271 NC-TTGDGNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNY--PCKGLDQNYCRNPDNE-RKPWCYTTDPETRWEYCNVESCGNEPRPDEPVIAPNEDCYEDNGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNFPTADLRRNLCRNPD 419          

HSP 3 Score: 61.6178 bits (148), Expect = 2.585e-11
Identity = 42/143 (29.37%), Postives = 63/143 (44.06%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            G  Y G  + +++G  C  W  +  +      S++ +    +E NYCRNP   P  PWC  +     WE C +  C      I  +  C   D G  Y G ++ T++GK C+ W  Q  +  +  P+      L  N CRNPD
Sbjct:  187 GENYRGKISTTESGLTCQRWDSQKPHNHGYMPSVFPE--KYLEENYCRNPDGEPK-PWCFTESPAKRWEFCSVSRCTSPPPTIVPQLNCTTGD-GNTYRGTVSVTESGKTCQSWASQLPHKHSRTPDNYPCKGLDQNYCRNPD 325          

HSP 4 Score: 50.8322 bits (120), Expect = 1.436e-7
Identity = 42/166 (25.30%), Postives = 64/166 (38.55%), Query Frame = 2
Query:  104 HGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--------------------------IKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQ----SNYSENSFPEKSFQLVGNKCRNPD 511
            +G  Y G    + +G+ C +W     +  +     +   T+ +  N CRNP +    PWC   +  + WE+C I  C                            E   CK T  G  Y G ++ T  G  C+ W       S+++  + P+K   L  NKCRNPD
Sbjct:  370 NGSSYRGVMTETISGKKCQAWASMEPHSHVKTPQNF--PTADLRRNLCRNP-DGDRAPWCYTTDPSVRWEYCRIERCGSTTVSLTPPPALKPVVPPTLLTQSVPSEFADCK-TGSGISYRGSVSKTVAGVTCQAWSASTPHLSSFTPQAHPDKG--LDSNKCRNPD 529          
BLAST of Prothrombin vs. Ensembl Cavefish
Match: f2 (coagulation factor II, thrombin [Source:NCBI gene;Acc:103039180])

HSP 1 Score: 67.3958 bits (163), Expect = 2.639e-13
Identity = 48/162 (29.63%), Postives = 69/162 (42.59%), Query Frame = 2
Query:   83 ENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--------------IKERNWCKD---TDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            ++C + T G  Y G  N++ +G+ C  WK  + + II  +         +  N+CRNP   P GPWC   +  +  E C +  C              I+ER + K       G  Y GDL+ T  G  C  W +    + +   E     QLV N CRNPD
Sbjct:  111 DHCYLNT-GEHYSGDVNLTISGKTCQYWKSNFPHRIIEINQTQLK----LPENFCRNPDKSPTGPWCFTSDPTVRREKCAVAKCGEPLQPVPTVKVGTIEER-YAKTKCIAGNGETYTGDLSVTLGGHTCLEWNLPKVKALSVGKEFKPDIQLVKNHCRNPD 266          
BLAST of Prothrombin vs. Ensembl Cavefish
Match: hgfb (hepatocyte growth factor [Source:NCBI gene;Acc:103033838])

HSP 1 Score: 66.2402 bits (160), Expect = 7.278e-13
Identity = 43/147 (29.25%), Postives = 67/147 (45.58%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDT------DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            +T +G  Y G  + +++GR C  W  +  ++ +     Y D    ++ NYCRNP      PWC   +  + WE+C I+ C  +     +T      D G  Y G +   + G  C+ W  Q  +S +  P+K     L  N CRNPD
Sbjct:  196 MTCNGESYRGPMDHTESGRECQRWDLDEPHKHLFHPKRYPDNG--LKDNYCRNPDGRQR-PWCFTTDPDVPWEYCSIKQCDSDNQSNIETTTTCFRDNGAGYRGTVAVPREGLTCQRWDAQFPHSHSYMPQKYRCKDLSENFCRNPD 339          

HSP 2 Score: 56.9954 bits (136), Expect = 1.297e-9
Identity = 40/138 (28.99%), Postives = 59/138 (42.75%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKERNWCKDTDKGTE--YLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511
            G  Y G   V + G  C  W  ++ +        Y      +  N+CRNP    + PWC   +  + W  C +I  C       ++  KG+E  Y G    T++G +C PW   S  ++      S +L GN CRNPD
Sbjct:  291 GAGYRGTVAVPREGLTCQRWDAQFPHSHSYMPQKY--RCKDLSENFCRNPDGR-DAPWCFTTDPNIPWAFCKNIPRCGAAATEPEECYKGSEETYRGKQMKTRSGILCAPWRDHSERNKREVVTLSEELEGNFCRNPD 425          

HSP 3 Score: 53.9138 bits (128), Expect = 1.194e-8
Identity = 39/146 (26.71%), Postives = 63/146 (43.15%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            ++ C I T G  Y G  + ++ G  C  W     +E       +      +  N CRNP N   GPWC      + +++C+I  C +       T  G  Y G ++ T++G+ C+ W +   +     P++     L  N CRNPD
Sbjct:  109 VKECIIGT-GLNYKGKISKTETGEECQKWDLNTPHEHHFLPRRH--KKKDLRDNLCRNPDNSTTGPWCFTKNPNIRYQNCNIPQCSEVECM---TCNGESYRGPMDHTESGRECQRWDLDEPHKHLFHPKRYPDNGLKDNYCRNPD 248          
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003778.1 (pep scaffold:Pmarinus_7.0:GL482904:4425:14035:-1 gene:ENSPMAG00000003419.1 transcript:ENSPMAT00000003778.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 71.633 bits (174), Expect = 2.191e-15
Identity = 42/160 (26.25%), Postives = 75/160 (46.88%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNW----------CKDTDK---------GTEYLGDLNFTKTGKICKPWIIQSNYSENSFP--EKSFQLVGNKCRNPD 511
            +T +G +Y+G  + +K+GR C  W   + +++     +      ++E N+CRNP    +GPWC   + ++  E C + +C K+ N            K   +         G +Y G +N T++G+ C+ W  Q+ +     P   ++  L G  CRNPD
Sbjct:  108 MTGNGEQYIGNVSFTKSGRQCQLWTSNFPHQVRFK-PVDHPEKQLVE-NFCRNPDASQDGPWCYTRDPLVPREPCSVPTCDKDPNQHVPVSPRVTPTKPAPRPQGPCVPGAGEDYRGPVNVTRSGRHCQAWSAQTPHVSRYSPLTHRAAGLEGAACRNPD 265          

HSP 2 Score: 46.595 bits (109), Expect = 9.536e-7
Identity = 28/68 (41.18%), Postives = 38/68 (55.88%), Query Frame = 2
Query:  326 RSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWII----QSNYSENSFPEKSFQLVGNKCRNPDMS 517
            R C+K    C  T  G +Y+G+++FTK+G+ C+ W      Q  +     PEK  QLV N CRNPD S
Sbjct:  100 RGCLK--GLCM-TGNGEQYIGNVSFTKSGRQCQLWTSNFPHQVRFKPVDHPEK--QLVENFCRNPDAS 162          
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: hgfb (hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GENE-041014-3])

HSP 1 Score: 61.6178 bits (148), Expect = 4.780e-12
Identity = 44/145 (30.34%), Postives = 62/145 (42.76%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCI-VDESILEWEHCHIRSCIKERNWCK-DTDKGTEYLGDLNFTKTGKICKPWIIQSN----YSENSFPEKSFQLVGNKCRNPD 511
            +   G +Y G  N +K G PC  W  +  +     +  Y    S ++ NYCRNP      PWC  +D S+      HI  C +     +  +  GT Y G +  T+ G  C+ W   S     Y+  S P     L G+ CRNPD
Sbjct:  228 LEERGEDYRGRANHTKGGIPCQHWAAQQPHRHTYLEHNY--PCSGLDRNYCRNPDGREEAPWCFTLDPSVRRQLCSHIPRCAQPTAGSQCYSGSGTAYRGGVATTRHGLQCQAWNATSPHKPWYTPKSHPGAG--LEGHSCRNPD 368          

HSP 2 Score: 60.8474 bits (146), Expect = 9.338e-12
Identity = 44/142 (30.99%), Postives = 68/142 (47.89%), Query Frame = 2
Query:   98 TTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIY--FDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEK--SFQLVGNKCRNPD 511
            T +G  Y G  N +++G PC +W     ++     S Y  FD    +E N CRNP   P  PWC   +S    E C I  C +    C +  +G  Y G ++ T + + C+ W +Q  ++ N  P++  +  L  N CRNP+
Sbjct:   53 TGNGSGYRGDKNYTESGLPCQAWGDSEPHDSRYLPSFYPAFD----LEGNSCRNPAQEPGEPWCYTMDSNRRRERCGIPRCDEVP--CVEC-RGEHYRGLVDHTDSQRECQRWDLQHPHNHNYTPDRFPNAGLDDNYCRNPN 187          

HSP 3 Score: 55.4546 bits (132), Expect = 8.221e-10
Identity = 44/159 (27.67%), Postives = 65/159 (40.88%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYL-NEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHI----------------RSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPD 511
            +   G  Y G  + + + R C  W  ++  N     D       + ++ NYCRNP N    PWC   +    WE+C I                R C++ER        G +Y G  N TK G  C+ W  Q  +  +++ E ++   G   N CRNPD
Sbjct:  135 VECRGEHYRGLVDHTDSQRECQRWDLQHPHNHNYTPDRF---PNAGLDDNYCRNP-NGRMRPWCFTTDPHQPWEYCSIKPGCCASKATRPAMEGRPCLEER--------GEDYRGRANHTKGGIPCQHWAAQQPH-RHTYLEHNYPCSGLDRNYCRNPD 280          

HSP 4 Score: 43.5134 bits (101), Expect = 8.728e-6
Identity = 25/107 (23.36%), Postives = 42/107 (39.25%), Query Frame = 2
Query:   38 LLLQSSFILSYFTEIENCKITTHGRE--------YVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
              L  S      + I  C   T G +        Y G    +++G  C +W     ++       +    + +E + CRNP   P GPWC   +  L W++C + +C
Sbjct:  289 FTLDPSVRRQLCSHIPRCAQPTAGSQCYSGSGTAYRGGVATTRHGLQCQAWNATSPHKPWYTPKSH--PGAGLEGHSCRNPDGDPWGPWCFTSDPHLPWDYCSVEAC 393          
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001728.1 (pep scaffold:Pmarinus_7.0:GL477419:32233:56220:-1 gene:ENSPMAG00000001561.1 transcript:ENSPMAT00000001728.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 54.299 bits (129), Expect = 1.277e-9
Identity = 29/106 (27.36%), Postives = 51/106 (48.11%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLN 397
            +++C  T  G  Y G   ++ +G  C +W  +  +        + +  + +E NYCRNP + PNGPWCI  +  + WE+C ++ C    +      + T   G+ N
Sbjct:    8 VDHC-YTGSGTGYRGLQTLTASGHQCQTWASKTPHLHAYTPEGFPE--AGLENNYCRNPDSDPNGPWCITQDPNVLWEYCALQRCASGPSPTGAEQRATLSRGEKN 110          

HSP 2 Score: 48.521 bits (114), Expect = 1.470e-7
Identity = 23/75 (30.67%), Postives = 34/75 (45.33%), Query Frame = 2
Query:  110 REYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            R Y G   V+  G+ C +W  +  +      + Y D  + +   YCRNP     GPWC   +S   W++C I  C
Sbjct:  213 RGYRGAQAVTSGGKTCQAWASQSPHRHQFVPANYTD--ADLSLGYCRNPDGDLAGPWCYTTDSATRWQYCGIAHC 285          
BLAST of Prothrombin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005055.1 (pep scaffold:Pmarinus_7.0:GL479085:195887:200886:-1 gene:ENSPMAG00000004594.1 transcript:ENSPMAT00000005055.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 45.8246 bits (107), Expect = 5.724e-7
Identity = 31/132 (23.48%), Postives = 55/132 (41.67%), Query Frame = 2
Query:    8 LMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSW------KKEYLN-------------EIIMDDSIYFDTTSI----IETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            L  N  + TA+    S +      +++C +   G  Y G  + + +GR C  W      + +YL               +++  S +F   +     +E N+CRNP +  +GPWC   +    WE C + +C
Sbjct:   15 LPVNSLMKTAIAKPGSSLYEKIVYLQDCMVGL-GISYRGTVSKTTSGRQCQFWSTNKPHRPKYLPFSRCEWTNARQHLSVMLSASHHFTPWTHPELGLEDNFCRNPDHGVSGPWCYTTDPAQRWEVCSVPAC 145          
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO30193 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T1H4])

HSP 1 Score: 55.8398 bits (133), Expect = 4.942e-11
Identity = 26/82 (31.71%), Postives = 41/82 (50.00%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEII-MDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN 349
            GR+Y G  N +  G  C  W +++ ++   M D +      + + NYCRNP    + PWC        W++C IRSC K ++
Sbjct:    2 GRDYRGTMNFTAKGVTCQPWNEQWPHQHTEMADPLVAAREGLGKHNYCRNPGGRKHRPWCYTTLEKTRWQYCEIRSCRKTKS 83          
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO43993 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RX97])

HSP 1 Score: 53.9138 bits (128), Expect = 4.824e-9
Identity = 29/76 (38.16%), Postives = 40/76 (52.63%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC 334
            G +Y+G  NV+K G PCLSWK         +D +Y      +  N+CRNP      PWC VD++   +E+C I  C
Sbjct:  137 GEDYIGRLNVTKYGMPCLSWKS--------NDPVY-----KLSHNFCRNPRGQHEAPWCYVDKNT--YEYCVIPKC 197          
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO39763 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S935])

HSP 1 Score: 50.0618 bits (118), Expect = 8.414e-9
Identity = 31/100 (31.00%), Postives = 46/100 (46.00%), Query Frame = 2
Query:   38 LLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNF-PNGPWCIVDESILEWEHCHIRSC 334
            L + S  I  Y+ E         G  Y G  NV+K+G  C  W  +  +    + + Y  T  I  +N+CRNP    P+GPWC     ++ WE+C +  C
Sbjct:    2 LSIPSPHIDCYYGE---------GVGYHGNINVTKSGISCQPWSSQCPHRHYHNSTQY--TELINASNFCRNPGGMGPDGPWCYTTNMMVRWEYCDVPKC 90          
BLAST of Prothrombin vs. Ensembl Nematostella
Match: EDO28926 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T536])

HSP 1 Score: 48.9062 bits (115), Expect = 1.465e-8
Identity = 25/77 (32.47%), Postives = 39/77 (50.65%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNF-PNGPWCIVDESILEWEHCHIRSC 334
            G  Y G  NV+K+G  C  W  +  +    + + Y +   I  +N+CRNP    P+GPWC     ++ WE+C +  C
Sbjct:    7 GVGYHGNINVTKSGISCQPWSSQCPHHHYHNSTQYPEL--INASNFCRNPGGMGPDGPWCYTTNKLVRWEYCDVPKC 81          
BLAST of Prothrombin vs. Ensembl Medaka
Match: f2 (prothrombin [Source:NCBI gene;Acc:101170246])

HSP 1 Score: 72.7886 bits (177), Expect = 3.661e-15
Identity = 48/159 (30.19%), Postives = 76/159 (47.80%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-------RNWCKDT----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511
            +E   ++ +G  Y G  +++K+GR C  W   + + I  + +   +  SI++ N+CRNP     GPWC   +  ++ E C +  C ++           K T    + G +Y GDL+ T  G  C  W   S  ++    +K F    QL GNKCRNPD
Sbjct:  107 VEGHCVSGNGHNYNGNIHITKSGRVCQHWSHSFPHPIFREFNAS-EPNSILQENFCRNPDKRSEGPWCFTKDPSVQKETCRVPKCGEKFVPPTVAPEVVKTTICLPNYGVDYTGDLSVTLGGHTCIQW--SSPQAKALSKDKEFIPEVQLTGNKCRNPD 262          
BLAST of Prothrombin vs. Ensembl Medaka
Match: f2 (prothrombin [Source:NCBI gene;Acc:101170246])

HSP 1 Score: 72.7886 bits (177), Expect = 3.661e-15
Identity = 48/159 (30.19%), Postives = 76/159 (47.80%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-------RNWCKDT----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511
            +E   ++ +G  Y G  +++K+GR C  W   + + I  + +   +  SI++ N+CRNP     GPWC   +  ++ E C +  C ++           K T    + G +Y GDL+ T  G  C  W   S  ++    +K F    QL GNKCRNPD
Sbjct:  107 VEGHCVSGNGHNYNGNIHITKSGRVCQHWSHSFPHPIFREFNAS-EPNSILQENFCRNPDKRSEGPWCFTKDPSVQKETCRVPKCGEKFVPPTVAPEVVKTTICLPNYGVDYTGDLSVTLGGHTCIQW--SSPQAKALSKDKEFIPEVQLTGNKCRNPD 262          
BLAST of Prothrombin vs. Ensembl Medaka
Match: f2 (prothrombin [Source:NCBI gene;Acc:101170246])

HSP 1 Score: 72.4034 bits (176), Expect = 5.173e-15
Identity = 47/154 (30.52%), Postives = 74/154 (48.05%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKE-------RNWCKDT----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSF----QLVGNKCRNPD 511
            ++ +G  Y G  +++K+GR C  W   + + I  + +   +  SI++ N+CRNP     GPWC   +  ++ E C +  C ++           K T    + G +Y GDL+ T  G  C  W   S  ++    +K F    QL GNKCRNPD
Sbjct:   85 VSGNGHNYNGNIHITKSGRVCQHWSHSFPHPIFREFNAS-EPNSILQENFCRNPDKRSEGPWCFTKDPSVQKETCRVPKCGEKFVPPTVAPEVVKTTICLPNYGVDYTGDLSVTLGGHTCIQW--SSPQAKALSKDKEFIPEVQLTGNKCRNPD 235          
BLAST of Prothrombin vs. Ensembl Medaka
Match: mst1 (hepatocyte growth factor-like protein [Source:NCBI gene;Acc:101168450])

HSP 1 Score: 68.5514 bits (166), Expect = 1.103e-13
Identity = 50/162 (30.86%), Postives = 80/162 (49.38%), Query Frame = 2
Query:   80 IENCK----ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC----IKERNWCKDT-----DKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVG---NKCRNPDMS 517
            I  CK    IT +G +Y G  + +  G+ C  W +++ ++ I     Y D +  ++ NYCRNP   P  PWC   + ++E E+C+I  C    +++R     T      +G +Y G +N T +G  C+ W  Q  + E+ F    ++  G   N CRNPD S
Sbjct:  182 IPQCKDEVCITCNGEDYRGQVDHTATGKECQRWDQQHPHQHIYQPEKYPDKS--LDDNYCRNPDASPV-PWCYTTDPLVERENCNISKCPEVPVEKRQRSSFTTNCFRGRGEDYRGKVNETLSGIPCQRWNAQFPH-EHPFHPNIYECKGLEENYCRNPDGS 339          

HSP 2 Score: 66.6254 bits (161), Expect = 5.683e-13
Identity = 50/146 (34.25%), Postives = 67/146 (45.89%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTS-IIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSN----YSENSFPEKSFQLVGNKCRNPDMS 517
            I   G +Y G    +K+G  C  W  ++ +     D  +  T S  +E NYCRNP     GPWC   +    +E C+I  C  E      T  G +Y G ++ T TGK C+ W  Q      Y    +P+KS  L  N CRNPD S
Sbjct:  110 IVGKGEDYRGKVFTTKSGLNCQQWWSKFPH-----DHWWTPTASNGLELNYCRNPDGDNIGPWCYTTDPERRYESCNIPQCKDE---VCITCNGEDYRGQVDHTATGKECQRWDQQHPHQHIYQPEKYPDKS--LDDNYCRNPDAS 245          

HSP 3 Score: 46.595 bits (109), Expect = 4.394e-6
Identity = 29/107 (27.10%), Postives = 48/107 (44.86%), Query Frame = 2
Query:   26 LATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKER 346
            + TAL LQ         E E+C    +G+ Y G    ++ G  C  W     +   ++   + +    +  NYCRNP    +GPWC   +   E+++C I+ C  E+
Sbjct:  351 MRTALCLQIKRCEDDI-EAEDC-YQENGKNYRGIVRKTRKGVTCQRWNVNTPHRTKINPLTHPEAN--LTENYCRNPDGDQHGPWCYTTDPKTEFDYCAIKQCAGEK 453          
BLAST of Prothrombin vs. Ensembl Medaka
Match: hgfb (hepatocyte growth factor [Source:NCBI gene;Acc:101167035])

HSP 1 Score: 65.0846 bits (157), Expect = 1.647e-12
Identity = 45/147 (30.61%), Postives = 72/147 (48.98%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSC--IKERNWCKDTD----KGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPE--KSFQLVGNKCRNPD 511
            I  +G +Y G  + +++G+ C  W  +  ++ +     Y D    ++ NYCRNP N  + PWC   +    WE+C I+ C    + N  + T+    KG  Y G ++ T TG  C+ W  Q  ++ +  PE  +   L  N CRNPD
Sbjct:  192 INCNGEDYRGPMDHTESGKECQRWDLDEPHKHLFHPKRYPDKG--LDDNYCRNP-NGRHRPWCFTTDPNTPWEYCTIKVCETPPDSNVVETTECFQGKGEGYRGVVDMTPTGLTCQRWDSQYPHNHSFIPEAYRCKDLRENYCRNPD 335          

HSP 2 Score: 55.8398 bits (133), Expect = 2.535e-9
Identity = 44/150 (29.33%), Postives = 68/150 (45.33%), Query Frame = 2
Query:   80 IENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEH--CHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSE----NSFPEKSFQLVGNKCRNPD 511
            +  C + T G+ Y G  +V+ NG  C +W     +E            S +  NYCRNP N   GPWC   +   +  H  C I  C +    C + + G +Y G ++ T++GK C+ W +   +        +P+K   L  N CRNP+
Sbjct:  103 VRECILGT-GQSYRGRRSVTVNGILCQAWASPIPHE--HKFMSKKFKKSDLRENYCRNPDNSTVGPWCFTTDPRPQLRHQECGIPQCSEVE--CINCN-GEDYRGPMDHTESGKECQRWDLDEPHKHLFHPKRYPDKG--LDDNYCRNPN 244          

HSP 3 Score: 48.1358 bits (113), Expect = 1.228e-6
Identity = 25/81 (30.86%), Postives = 40/81 (49.38%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERN 349
            G  Y G  + +++  PC  W+ E+ N       +       +E NYCRNP    +GPWC  + S + W++C I+ C   +N
Sbjct:  375 GENYRGQQSRTRSNLPCGPWR-EHSNSGERGMLMVG-----LEGNYCRNPDGDKHGPWCYTNNSAISWDYCSIKPCDASQN 449          

HSP 4 Score: 48.1358 bits (113), Expect = 1.275e-6
Identity = 40/139 (28.78%), Postives = 57/139 (41.01%), Query Frame = 2
Query:  107 GREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHC-HIRSCIKE---RNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPD 511
            G  Y G  +++  G  C  W  +Y +        Y      +  NYCRNP +  + PWC   +  +    C +I  C  +    N C ++  G  Y G  + T++   C PW   SN  E         L GN CRNPD
Sbjct:  287 GEGYRGVVDMTPTGLTCQRWDSQYPHNHSFIPEAY--RCKDLRENYCRNP-DGQDFPWCFTTDPRVRTMFCTNIPQCGTQNRLANECYES-LGENYRGQQSRTRSNLPCGPWREHSNSGERGM--LMVGLEGNYCRNPD 419          
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026377.1 (SMESG000026377.1)

HSP 1 Score: 360.147 bits (923), Expect = 1.418e-118
Identity = 168/169 (99.41%), Postives = 169/169 (100.00%), Query Frame = 2
Query:   11 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517
            MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLN+IIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS
Sbjct:    1 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNDIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 169          
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026376.1 (SMESG000026376.1)

HSP 1 Score: 236.113 bits (601), Expect = 1.479e-72
Identity = 104/169 (61.54%), Postives = 127/169 (75.15%), Query Frame = 2
Query:   11 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517
            M  + L+    LQ      YF EIE CKI+THG EY+G  N  K+G+ C+ WK EY+N+I+MDD+  FD TSII  NYCRNPTNFPNGPWCI+DE  LEWEHC+I  C+K+RNWCKD+DKGTEYLGD++ TK+GK+CKPWI    ++ NSFPE +  L GNKCRNPDMS
Sbjct:    1 MLIVQLSAIFYLQCVIFAGYFEEIEKCKISTHGGEYMGKVNYGKSGQRCIFWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGPWCIIDEMTLEWEHCNIIKCVKDRNWCKDSDKGTEYLGDISHTKSGKMCKPWINFRKHTANSFPENNVHLAGNKCRNPDMS 169          
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026355.1 (SMESG000026355.1)

HSP 1 Score: 233.417 bits (594), Expect = 1.715e-71
Identity = 101/161 (62.73%), Postives = 133/161 (82.61%), Query Frame = 2
Query:   35 ALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517
            AL L S    SYFT+IENCKITTHGRE++G T+++KNG+ C++WK+E++N++     I +D+ S+I  NYCRNPTNFPNGPWCI+DE+ L+WE+C+I+SCIK+RNWCKDT+ G EYLGD+N+TK+GK C PWI Q  + ++SFPEK+  LVGNKCRNPDMS
Sbjct:    9 ALPLLSRLTSSYFTDIENCKITTHGREFIGRTSITKNGQQCITWKEEFINKLQAGKIINYDSKSLIGNNYCRNPTNFPNGPWCIIDENTLKWEYCNIKSCIKDRNWCKDTENGREYLGDVNYTKSGKDCNPWINQRTHPKDSFPEKNLNLVGNKCRNPDMS 169          
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026362.1 (SMESG000026362.1)

HSP 1 Score: 228.024 bits (580), Expect = 1.224e-69
Identity = 102/169 (60.36%), Postives = 124/169 (73.37%), Query Frame = 2
Query:   11 MFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517
            M  + L+    LQ      YF EIE C++TTHG EY+G  N  K+G+ C+ WK EY+N I+MDD+  F  TSII  NYCRNPTNFP GPWCI+DE  LEWEHC+I  CIK+RNWCKD+DKGTEYLGD++ TK+GK+CKPWI    ++ NSFPE +  L GNKCRNPDMS
Sbjct:    1 MLIVQLSVIFSLQYVTFAGYFEEIEKCRMTTHGGEYMGKVNFGKSGQRCIFWKNEYVNHIVMDDTFVFVNTSIIGNNYCRNPTNFPRGPWCIIDEITLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKMCKPWINFRKHTANSFPENNVHLAGNKCRNPDMS 169          
BLAST of Prothrombin vs. Planmine SMEST
Match: SMESG000026361.1 (SMESG000026361.1)

HSP 1 Score: 211.075 bits (536), Expect = 1.237e-63
Identity = 90/141 (63.83%), Postives = 113/141 (80.14%), Query Frame = 2
Query:   95 ITTHGREYVGYTNVSKNGRPCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESILEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYSENSFPEKSFQLVGNKCRNPDMS 517
            +TTHGREY+G  +  K+G+ C+ WK EY+N+I+MDD+  FD TSII  NYCRNPTNFPNG WCI+DE  LEWEHC+I  CIK+RNWCKD+DKGTEYLGD++ TK+GK+C+PWI    +   SFPE++ +  GNKCRNPDMS
Sbjct:    1 MTTHGREYMGKVDFVKSGQRCIVWKNEYVNQILMDDTFVFDNTSIIGNNYCRNPTNFPNGLWCIIDEMTLEWEHCNIIKCIKDRNWCKDSDKGTEYLGDISHTKSGKLCQPWINFGTHRAYSFPERNLKFAGNKCRNPDMS 141          
The following BLAST results are available for this feature:
BLAST of Prothrombin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MST12.152e-1633.10macrophage stimulating 1 [Source:HGNC Symbol;Acc:H... [more]
HGF7.293e-1532.88hepatocyte growth factor [Source:HGNC Symbol;Acc:H... [more]
PLG7.384e-1530.72plasminogen [Source:HGNC Symbol;Acc:HGNC:9071][more]
HGF1.690e-1433.11hepatocyte growth factor [Source:HGNC Symbol;Acc:H... [more]
HGF4.022e-1432.19hepatocyte growth factor [Source:HGNC Symbol;Acc:H... [more]
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BLAST of Prothrombin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Prothrombin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Nrk1.346e-939.24gene:FBgn0020391 transcript:FBtr0087728[more]
Ror1.541e-841.77gene:FBgn0010407 transcript:FBtr0079978[more]
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BLAST of Prothrombin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plg3.561e-1528.31plasminogen [Source:ZFIN;Acc:ZDB-GENE-030131-1411][more]
mst11.601e-1432.30macrophage stimulating 1 [Source:ZFIN;Acc:ZDB-GENE... [more]
hgfb1.038e-1128.57hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GE... [more]
hgfa4.064e-1129.79hepatocyte growth factor a [Source:ZFIN;Acc:ZDB-GE... [more]
hgfa4.291e-1129.79hepatocyte growth factor a [Source:ZFIN;Acc:ZDB-GE... [more]
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BLAST of Prothrombin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
MST11.409e-1632.70macrophage stimulating 1 [Source:NCBI gene;Acc:100... [more]
MST11.018e-1530.91macrophage stimulating 1 [Source:NCBI gene;Acc:100... [more]
MST11.085e-1530.91macrophage stimulating 1 [Source:NCBI gene;Acc:100... [more]
MST11.205e-1530.91macrophage stimulating 1 [Source:NCBI gene;Acc:100... [more]
ENSXETT00000037773.13.077e-1530.46plasminogen [Source:NCBI gene;Acc:100496227][more]
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BLAST of Prothrombin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Mst11.225e-1632.64macrophage stimulating 1 (hepatocyte growth factor... [more]
Mst11.228e-1632.64macrophage stimulating 1 (hepatocyte growth factor... [more]
Plg2.545e-1428.24plasminogen [Source:MGI Symbol;Acc:MGI:97620][more]
Hgf2.316e-1331.76hepatocyte growth factor [Source:MGI Symbol;Acc:MG... [more]
Hgf2.316e-1331.76hepatocyte growth factor [Source:MGI Symbol;Acc:MG... [more]
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BLAST of Prothrombin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P26928|HGFL_MOUSE8.588e-1632.64Hepatocyte growth factor-like protein OS=Mus muscu... [more]
sp|P26927|HGFL_HUMAN1.030e-1533.10Hepatocyte growth factor-like protein OS=Homo sapi... [more]
sp|Q29485|PLMN_ERIEU6.290e-1530.63Plasminogen OS=Erinaceus europaeus OX=9365 GN=PLG ... [more]
sp|O18783|PLMN_MACEU3.281e-1433.56Plasminogen OS=Macropus eugenii OX=9315 GN=PLG PE=... [more]
sp|P00747|PLMN_HUMAN3.546e-1430.72Plasminogen OS=Homo sapiens OX=9606 GN=PLG PE=1 SV... [more]
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BLAST of Prothrombin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
R7VDJ12.342e-1831.10Uncharacterized protein OS=Capitella teleta OX=283... [more]
R7USY46.970e-1730.67Uncharacterized protein OS=Capitella teleta OX=283... [more]
H3CM773.409e-1633.77Prothrombin OS=Tetraodon nigroviridis OX=99883 PE=... [more]
A0A2U9AVB14.001e-1632.08Putative prothrombin isoform 3 OS=Scophthalmus max... [more]
A0A5E4MF174.260e-1630.43Immunoglobulin-like fold,Kringle,Kringle-like fold... [more]
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BLAST of Prothrombin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
mst15.701e-1633.11macrophage stimulating 1 [Source:NCBI gene;Acc:103... [more]
ENSAMXT00000018418.21.906e-1430.94plasminogen [Source:NCBI gene;Acc:103036400][more]
ENSAMXT00000018419.21.919e-1430.94plasminogen [Source:NCBI gene;Acc:103036400][more]
f22.639e-1329.63coagulation factor II, thrombin [Source:NCBI gene;... [more]
hgfb7.278e-1329.25hepatocyte growth factor [Source:NCBI gene;Acc:103... [more]
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BLAST of Prothrombin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000003778.12.191e-1526.25pep scaffold:Pmarinus_7.0:GL482904:4425:14035:-1 g... [more]
hgfb4.780e-1230.34hepatocyte growth factor b [Source:ZFIN;Acc:ZDB-GE... [more]
ENSPMAT00000001728.11.277e-927.36pep scaffold:Pmarinus_7.0:GL477419:32233:56220:-1 ... [more]
ENSPMAT00000005055.15.724e-723.48pep scaffold:Pmarinus_7.0:GL479085:195887:200886:-... [more]
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BLAST of Prothrombin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Prothrombin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO301934.942e-1131.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO439934.824e-938.16Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO397638.414e-931.00Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO289261.465e-832.47Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Prothrombin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
f23.661e-1530.19prothrombin [Source:NCBI gene;Acc:101170246][more]
f23.661e-1530.19prothrombin [Source:NCBI gene;Acc:101170246][more]
f25.173e-1530.52prothrombin [Source:NCBI gene;Acc:101170246][more]
mst11.103e-1330.86hepatocyte growth factor-like protein [Source:NCBI... [more]
hgfb1.647e-1230.61hepatocyte growth factor [Source:NCBI gene;Acc:101... [more]
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BLAST of Prothrombin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000026377.11.418e-11899.41SMESG000026377.1[more]
SMESG000026376.11.479e-7261.54SMESG000026376.1[more]
SMESG000026355.11.715e-7162.73SMESG000026355.1[more]
SMESG000026362.11.224e-6960.36SMESG000026362.1[more]
SMESG000026361.11.237e-6363.83SMESG000026361.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035288 ID=SMED30035288|Name=Prothrombin|organism=Schmidtea mediterranea sexual|type=transcript|length=517bp
TGCAAATTTAATGTTTAATATCTTTCTTGCAACTGCTCTACTTTTACAAA
GCAGTTTTATTTTATCATATTTTACAGAAATAGAAAACTGTAAAATCACG
ACTCATGGTAGAGAATATGTTGGATATACTAATGTATCTAAAAATGGGCG
ACCATGCCTTTCTTGGAAAAAAGAATATTTAAACGAAATTATTATGGATG
ATTCTATTTATTTTGACACTACTTCAATAATTGAAACCAATTATTGCAGA
AATCCTACAAACTTTCCTAACGGTCCCTGGTGCATTGTCGATGAGAGCAT
ATTAGAATGGGAGCACTGCCATATTAGGAGCTGTATTAAAGAACGAAATT
GGTGCAAAGATACCGACAAAGGGACAGAGTATCTCGGTGACTTAAATTTC
ACAAAAACCGGAAAGATTTGCAAGCCATGGATAATCCAAAGTAATTATTC
TGAAAATTCCTTTCCAGAAAAGAGTTTCCAACTTGTTGGAAATAAATGTC
GTAATCCAGATATGTCC
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protein sequence of SMED30035288-orf-1

>SMED30035288-orf-1 ID=SMED30035288-orf-1|Name=SMED30035288-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=172bp
ANLMFNIFLATALLLQSSFILSYFTEIENCKITTHGREYVGYTNVSKNGR
PCLSWKKEYLNEIIMDDSIYFDTTSIIETNYCRNPTNFPNGPWCIVDESI
LEWEHCHIRSCIKERNWCKDTDKGTEYLGDLNFTKTGKICKPWIIQSNYS
ENSFPEKSFQLVGNKCRNPDMS
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0005509calcium ion binding
GO:0008233peptidase activity
GO:0008236serine-type peptidase activity
GO:0016787hydrolase activity
GO:0004252serine-type endopeptidase activity
Vocabulary: cellular component
TermDefinition
GO:0005576extracellular region
Vocabulary: biological process
TermDefinition
GO:0006953acute-phase response
GO:0007596blood coagulation
GO:0007599hemostasis
GO:0006508proteolysis
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR038178Kringle_sf
IPR000001Kringle
IPR018056Kringle_CS
IPR013806Kringle-like
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00018KRINGLEcoord: 47..59
score: 29.9
coord: 75..95
score: 33.6
coord: 100..111
score: 34.91
NoneNo IPR availablePANTHERPTHR24261FAMILY NOT NAMEDcoord: 29..111
coord: 118..170
NoneNo IPR availableSIGNALP_EUKSignalP-noTMSignalP-noTMcoord: 1..22
score: 0.727
IPR000001KringleSMARTSM00130KR_2coord: 28..113
e-value: 6.9E-9
score: 44.0
IPR000001KringlePFAMPF00051Kringlecoord: 33..111
e-value: 9.9E-16
score: 57.8
coord: 122..171
e-value: 1.3E-6
score: 28.7
IPR000001KringlePROSITEPS50070KRINGLE_2coord: 123..172
score: 9.011
IPR000001KringlePROSITEPS50070KRINGLE_2coord: 35..111
score: 15.335
IPR038178Kringle superfamilyGENE3DG3DSA:2.40.20.10coord: 115..172
e-value: 7.9E-9
score: 37.6
coord: 16..114
e-value: 1.1E-19
score: 72.9
IPR018056Kringle, conserved sitePROSITEPS00021KRINGLE_1coord: 81..94
IPR013806Kringle-like foldSUPERFAMILYSSF57440Kringle-likecoord: 19..113
IPR013806Kringle-like foldSUPERFAMILYSSF57440Kringle-likecoord: 121..170