Wilms tumor protein 1-interacting protein homolog

Overview


Name	Wilms tumor protein 1-interacting protein homolog
Smed ID	SMED30035262
Length (bp)	830

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Wilms tumor protein 1-interacting protein homolog (SMED30035262) t-SNE clustered cells

Violin plots show distribution of expression levels for Wilms tumor protein 1-interacting protein homolog (SMED30035262) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Wilms tumor protein 1-interacting protein homolog (SMED30035262) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035262

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 3

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
cephalic ganglia	SMED30035262	SMESG000031934.1	dd_Smed_v4_7984_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30035262	SMESG000031934.1	dd_Smed_v4_7984_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30035262	SMESG000031934.1	dd_Smed_v4_7984_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
Match: WTIP (WT1 interacting protein [Source:HGNC Symbol;Acc:HGNC:20964])

HSP 1 Score: 176.022 bits (445), Expect = 2.897e-54
Identity = 76/159 (47.80%), Postives = 112/159 (70.44%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   I  A+ ACQAMG L+H +CF+C  C R+L+GK FY    K++C+ED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC++CNECLDG PFT+D +  I C++DY+   +  C SC +PI+P +   +T +VV +++++H AC+ 
Sbjct:   40 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACYH 198

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
Match: LIMD1 (LIM domains containing 1 [Source:HGNC Symbol;Acc:HGNC:6612])

HSP 1 Score: 185.267 bits (469), Expect = 2.547e-53
Identity = 82/157 (52.23%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +CS  +  A  ACQAMG L+H+ CF+C  C R+L+GK FY  +GK+FCEED+LY GFQQSADRC +CGH+I + IL+A G  YH  CFRC ICNECLDG PFT+D + KI C++DY+   +  C +C  PI+P + S  T +VV +++++H  C+
Sbjct:  472 CVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECY 628

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
Match: WTIP (WT1 interacting protein [Source:HGNC Symbol;Acc:HGNC:20964])

HSP 1 Score: 178.333 bits (451), Expect = 1.522e-52
Identity = 76/158 (48.10%), Postives = 112/158 (70.89%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   I  A+ ACQAMG L+H +CF+C  C R+L+GK FY    K++C+ED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC++CNECLDG PFT+D +  I C++DY+   +  C SC +PI+P +   +T +VV +++++H AC+
Sbjct:  224 ICIKCGLGIYGAQQACQAMGSLYHTDCFTCDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVACY 381

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
Match: LIMD1 (LIM domains containing 1 [Source:HGNC Symbol;Acc:HGNC:6612])

HSP 1 Score: 170.629 bits (431), Expect = 3.042e-48
Identity = 76/137 (55.47%), Postives = 99/137 (72.26%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEK 475
            C +CS  +  A  ACQAMG L+H+ CF+C  C R+L+GK FY  +GK+FCEED+LY GFQQSADRC +CGH+I + IL+A G  YH  CFRC ICNECLDG PFT+D + KI C++DY+   +  C +C  PI+P +
Sbjct:  472 CVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPE 608

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
Match: AJUBA (ajuba LIM protein [Source:HGNC Symbol;Acc:HGNC:20250])

HSP 1 Score: 160.614 bits (405), Expect = 4.793e-45
Identity = 69/157 (43.95%), Postives = 107/157 (68.15%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C+  I    +ACQA+  L+H  CF CC C R L+ K FY  +G ++CEEDYL+ GFQ++A++C +CGH+I  KIL+A G  YH  CFRC +CN+CLDG PFT+D   ++ C+ DY+ +++  C +C QPI+P +      +V+ +++++HF C+
Sbjct:  338 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGIPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECY 494

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Celegans
Match: zyx-1 (Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4])

HSP 1 Score: 114.775 bits (286), Expect = 4.777e-31
Identity = 58/159 (36.48%), Postives = 86/159 (54.09%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C  C   I   +  C AM  +FH +CF C  C + L G  FY    K  CE  Y     Q S ++C  C   I++K+L+A G  YHV+CF C  C + LDG PFTLDKD  + C+  ++   +  C  C++PI+P+     + +VV ++K FH  C++
Sbjct:    7 ICVGCGKEITGDQPGCNAMNQIFHVDCFKCGQCSKTLAGASFYNIDDKPTCEGCY-----QNSLEKCTACNRAISDKLLRACGGVYHVNCFVCFSCKKSLDGIPFTLDKDNNVHCVPCFHDKFAPRCALCSKPIVPQDGEKESVRVVAMDKSFHVDCYK 160

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Celegans
Match: zyx-1 (Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4])

HSP 1 Score: 114.775 bits (286), Expect = 1.374e-30
Identity = 58/159 (36.48%), Postives = 86/159 (54.09%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C  C   I   +  C AM  +FH +CF C  C + L G  FY    K  CE  Y     Q S ++C  C   I++K+L+A G  YHV+CF C  C + LDG PFTLDKD  + C+  ++   +  C  C++PI+P+     + +VV ++K FH  C++
Sbjct:   52 ICVGCGKEITGDQPGCNAMNQIFHVDCFKCGQCSKTLAGASFYNIDDKPTCEGCY-----QNSLEKCTACNRAISDKLLRACGGVYHVNCFVCFSCKKSLDGIPFTLDKDNNVHCVPCFHDKFAPRCALCSKPIVPQDGEKESVRVVAMDKSFHVDCYK 205

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Celegans
Match: zyx-1 (Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4])

HSP 1 Score: 114.39 bits (285), Expect = 1.520e-29
Identity = 58/159 (36.48%), Postives = 86/159 (54.09%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C  C   I   +  C AM  +FH +CF C  C + L G  FY    K  CE  Y     Q S ++C  C   I++K+L+A G  YHV+CF C  C + LDG PFTLDKD  + C+  ++   +  C  C++PI+P+     + +VV ++K FH  C++
Sbjct:  144 ICVGCGKEITGDQPGCNAMNQIFHVDCFKCGQCSKTLAGASFYNIDDKPTCEGCY-----QNSLEKCTACNRAISDKLLRACGGVYHVNCFVCFSCKKSLDGIPFTLDKDNNVHCVPCFHDKFAPRCALCSKPIVPQDGEKESVRVVAMDKSFHVDCYK 297

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Celegans
Match: zyx-1 (Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4])

HSP 1 Score: 112.079 bits (279), Expect = 9.719e-28
Identity = 58/160 (36.25%), Postives = 87/160 (54.37%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCG-FQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C  C   I   +  C AM  +FH +CF C  C + L G  FY    K  CE      G +Q S ++C  C   I++K+L+A G  YHV+CF C  C + LDG PFTLDKD  + C+  ++   +  C  C++PI+P+     + +VV ++K FH  C++
Sbjct:  410 ICVGCGKEITGDQPGCNAMNQIFHVDCFKCGQCSKTLAGASFYNIDDKPTCE------GCYQNSLEKCTACNRAISDKLLRACGGVYHVNCFVCFSCKKSLDGIPFTLDKDNNVHCVPCFHDKFAPRCALCSKPIVPQDGEKESVRVVAMDKSFHVDCYK 563

[Close]

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCG-FQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C  C   I   +  C AM  +FH +CF C  C + L G  FY    K  CE      G +Q S ++C  C   I++K+L+A G  YHV+CF C  C + LDG PFTLDKD  + C+  ++   +  C  C++PI+P+     + +VV ++K FH  C++
Sbjct:  410 ICVGCGKEITGDQPGCNAMNQIFHVDCFKCGQCSKTLAGASFYNIDDKPTCE------GCYQNSLEKCTACNRAISDKLLRACGGVYHVNCFVCFSCKKSLDGIPFTLDKDNNVHCVPCFHDKFAPRCALCSKPIVPQDGEKESVRVVAMDKSFHVDCYK 563

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
Match: jub (gene:FBgn0030530 transcript:FBtr0340292)

HSP 1 Score: 181.8 bits (460), Expect = 3.583e-52
Identity = 81/158 (51.27%), Postives = 107/158 (67.72%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C  C   +  A  ACQAMG L+H NCF CC C R L+GK FY  HG+++CEEDY+Y GFQQ+A++C ICGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D D KI C+ DY+   +  C SC + I P + +  T +VV ++K+FH  C+
Sbjct:  505 ICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCY 662

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
Match: jub (gene:FBgn0030530 transcript:FBtr0303418)

HSP 1 Score: 181.8 bits (460), Expect = 3.583e-52
Identity = 81/158 (51.27%), Postives = 107/158 (67.72%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C  C   +  A  ACQAMG L+H NCF CC C R L+GK FY  HG+++CEEDY+Y GFQQ+A++C ICGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D D KI C+ DY+   +  C SC + I P + +  T +VV ++K+FH  C+
Sbjct:  505 ICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCY 662

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
Match: jub (gene:FBgn0030530 transcript:FBtr0073834)

HSP 1 Score: 181.8 bits (460), Expect = 4.062e-52
Identity = 81/158 (51.27%), Postives = 107/158 (67.72%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C  C   +  A  ACQAMG L+H NCF CC C R L+GK FY  HG+++CEEDY+Y GFQQ+A++C ICGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D D KI C+ DY+   +  C SC + I P + +  T +VV ++K+FH  C+
Sbjct:  515 ICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCY 672

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
Match: jub (gene:FBgn0030530 transcript:FBtr0303419)

HSP 1 Score: 175.252 bits (443), Expect = 7.203e-50
Identity = 81/163 (49.69%), Postives = 107/163 (65.64%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYL-----YCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C  C   +  A  ACQAMG L+H NCF CC C R L+GK FY  HG+++CEEDY+     Y GFQQ+A++C ICGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D D KI C+ DY+   +  C SC + I P + +  T +VV ++K+FH  C+
Sbjct:  505 ICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMNSLLQYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCY 667

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
Match: Zyx (gene:FBgn0011642 transcript:FBtr0309882)

HSP 1 Score: 116.701 bits (291), Expect = 1.688e-29
Identity = 58/158 (36.71%), Postives = 86/158 (54.43%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C +C+  +      C AM  ++H  CF+C  C   L+GK FY   GK +CE DYL     Q+ ++C +C   I  +IL+A G  YH  CF C +C + LDG  FT+D   +  CI D++   +  C  C QPI+P+     T +VV L++ FH  C++
Sbjct:  299 CVKCNSRVLGESSGCTAMDQIYHIFCFTCTDCQINLQGKPFYALDGKPYCEYDYL-----QTLEKCSVCMEPILERILRATGKPYHPQCFTCVVCGKSLDGLLFTVDATNQNYCITDFHKKFAPRCCVCKQPIMPDPGQEETIRVVALDRSFHLECYK 451

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Zebrafish
Match: wtip (WT1 interacting protein [Source:NCBI gene;Acc:566046])

HSP 1 Score: 184.882 bits (468), Expect = 1.571e-53
Identity = 81/158 (51.27%), Postives = 111/158 (70.25%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+A++C +CGH+I   IL+A G  YH  CFRC IC E LDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+
Sbjct:  438 ICVKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTAEKCFVCGHLIMEMILQALGRSYHPGCFRCVICKEGLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVDCY 595

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Zebrafish
Match: ajuba (ajuba LIM protein [Source:ZFIN;Acc:ZDB-GENE-030131-9341])

HSP 1 Score: 162.155 bits (409), Expect = 4.904e-45
Identity = 68/157 (43.31%), Postives = 106/157 (67.52%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C   +  A++ACQA+  L+H  CF+C  C R L+ K FY  +G ++C+EDY++ GFQ++A++C +CGH+I  +IL+A GN YH  CFRCT+C++ LDG PFT+D    + C+ DY  + +  C +C QPI+P + S    +VV + K++HF C+
Sbjct:  486 CVKCGKGVYGADNACQALDSLYHTRCFTCVSCGRTLRNKDFYNVNGSVYCKEDYMFSGFQEAAEKCSVCGHLILEQILQALGNSYHPGCFRCTVCSKALDGVPFTVDYLNNVYCVSDYNRTFAPKCAACLQPILPAEGSEEILRVVSMNKDYHFECY 642

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Zebrafish
Match: zyx (zyxin [Source:ZFIN;Acc:ZDB-GENE-070928-18])

HSP 1 Score: 136.346 bits (342), Expect = 4.527e-36
Identity = 70/159 (44.03%), Postives = 94/159 (59.12%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +++++ A +AM  LFH++CF C  C R L+G  FY   G   CEE Y+      S   C  CG  IT+++LKA G  +H  CF CT CN  L+GAPF  D D K  C+KDY+   S  C SCN+PIIP+  S  T +VV LEK FH  C++
Sbjct:  416 VCGKCGETLSRSQPAVRAMDKLFHSHCFCCVSCQRPLQGMQFYDRDGTPQCEECYM-----SSLSVCSRCGERITDRVLKAMGQCFHAHCFLCTTCNCSLEGAPFITDDDNKPYCVKDYHRRFSPLCVSCNEPIIPDPGSEETVRVVALEKNFHLKCYR 569

[Close]

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +++++ A +AM  LFH++CF C  C R L+G  FY   G   CEE Y+      S   C  CG  IT+++LKA G  +H  CF CT CN  L+GAPF  D D K  C+KDY+   S  C SCN+PIIP+  S  T +VV LEK FH  C++
Sbjct:  416 VCGKCGETLSRSQPAVRAMDKLFHSHCFCCVSCQRPLQGMQFYDRDGTPQCEECYM-----SSLSVCSRCGERITDRVLKAMGQCFHAHCFLCTTCNCSLEGAPFITDDDNKPYCVKDYHRRFSPLCVSCNEPIIPDPGSEETVRVVALEKNFHLKCYR 569

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Zebrafish
Match: lpp (LIM domain containing preferred translocation partner in lipoma [Source:ZFIN;Acc:ZDB-GENE-040426-918])

HSP 1 Score: 117.472 bits (293), Expect = 2.108e-29
Identity = 57/158 (36.08%), Postives = 84/158 (53.16%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C  C   +      C AM  +FH +CF C  C  +L+GK FY    K +CE  Y+      + + C IC   I  +IL+A G  YH  CF C +C+  LDG PFT+D    I CI+D++   +  C  CN+PI+P      T ++V L+++FH  C++
Sbjct:  360 CSSCGENVVGEGTGCTAMDQVFHVDCFICMTCGSKLRGKPFYAVEKKAYCEPCYI-----NTLETCNICYKPIMERILRATGKAYHPQCFTCVVCHRSLDGIPFTVDASNHIHCIEDFHKKFAPRCSVCNEPIMPAPGQEETVRIVALDRDFHVQCYR 512

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
Match: arf4 (ADP ribosylation factor 4 [Source:Xenbase;Acc:XB-GENE-484079])

HSP 1 Score: 191.815 bits (486), Expect = 1.059e-55
Identity = 83/158 (52.53%), Postives = 113/158 (71.52%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+
Sbjct:  488 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECY 645

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
Match: arf4 (ADP ribosylation factor 4 [Source:Xenbase;Acc:XB-GENE-484079])

HSP 1 Score: 191.43 bits (485), Expect = 3.074e-55
Identity = 83/158 (52.53%), Postives = 113/158 (71.52%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+
Sbjct:  550 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECY 707

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
Match: gnpda1 (glucosamine-6-phosphate deaminase 1 [Source:Xenbase;Acc:XB-GENE-966376])

HSP 1 Score: 178.333 bits (451), Expect = 2.611e-51
Identity = 80/158 (50.63%), Postives = 111/158 (70.25%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C +CS  +  A  ACQAMG L+HN CF C  C R+L+GK FY  +GK++CEED+LY GF QSADRC +CGH I + IL+A G  +H  CFRC +CNECLDG PFT+D + KI C+KDY+   +  C +C+ PI+P + +  T +VV ++K++H  C++
Sbjct:  393 CVKCSKGVYGANQACQAMGNLYHNGCFICSACSRKLRGKAFYFVNGKVYCEEDFLYSGFHQSADRCFVCGHWIMDMILQALGKSFHPGCFRCAVCNECLDGVPFTVDMENKIYCVKDYHKILAPKCAACSLPILPSEGTDETIRVVSMDKDYHIDCYR 550

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
Match: arf4 (ADP ribosylation factor 4 [Source:Xenbase;Acc:XB-GENE-484079])

HSP 1 Score: 156.377 bits (394), Expect = 6.581e-43
Identity = 67/127 (52.76%), Postives = 92/127 (72.44%), Query Frame = 2

Query:  155 YCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            Y  R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+
Sbjct:  485 YFGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECY 611

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
Match: nudt17 (nudix hydrolase 17 [Source:Xenbase;Acc:XB-GENE-979158])

HSP 1 Score: 122.479 bits (306), Expect = 6.825e-32
Identity = 56/158 (35.44%), Postives = 87/158 (55.06%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C +C   +      C AM  +FH  CF+C  C  +L+G+ FY    K FCE  Y+     ++ ++C +C   I  +IL+A G  YH  CF C +C   LDG PFT+D  G+I CI+D++   +  C  C +PI+P      T ++V L+++FH  C++
Sbjct:  185 CSRCGENVVGEGTGCTAMDQVFHVECFTCMTCNSKLRGQPFYAVEKKAFCEPCYI-----RTLEKCSVCAKPIMERILRATGKAYHPHCFTCVVCFRSLDGIPFTVDASGQIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYR 337

HSP 2 Score: 50.447 bits (119), Expect = 1.236e-6
Identity = 38/116 (32.76%), Postives = 55/116 (47.41%), Query Frame = 2

Query:   98 EDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKD-HGKLFCEEDYLYCGFQQSADRCKIC--------GHMITNKILKADGNYYHVDCFRCTICNECLDGAP----FTLDKDGKILC 406
            E   +A G  +H +CF+C  C+R L G  F  D  G++ C ED+     ++ A RC +C        G   T +I+  D ++ HV C+RC  C   L        + L  DG ILC
Sbjct:  254 ERILRATGKAYHPHCFTCVVCFRSLDGIPFTVDASGQIHCIEDF----HKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDF-HVQCYRCEDCGSLLSEGENQGCYPL--DGHILC 362

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
Match: Limd1 (LIM domains containing 1 [Source:MGI Symbol;Acc:MGI:1352502])

HSP 1 Score: 184.111 bits (466), Expect = 4.036e-53
Identity = 82/157 (52.23%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +CS  +  A  ACQAMG L+H+ CF+C  C R+L+GK FY  +GK+FCEED+LY GFQQSADRC +CGH+I + IL+A G  YH  CFRC ICNECLDG PFT+D + KI C++DY+   +  C +C  PI+P + S  T +VV +++++H  C+
Sbjct:  464 CVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECY 620

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
Match: Wtip (WT1-interacting protein [Source:MGI Symbol;Acc:MGI:2141920])

HSP 1 Score: 175.637 bits (444), Expect = 6.011e-52
Identity = 76/158 (48.10%), Postives = 109/158 (68.99%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   I  A  ACQAMG L+H +CF C  C R+L+GK FY    K++C+ED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC++CNECLDG PFT+D D  I C++DY+   +  C SC +PI+P +   +T +VV +++++H  C+
Sbjct:  192 ICIKCGLGIYGARQACQAMGSLYHTDCFICDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSYHPGCFRCSVCNECLDGVPFTVDVDNNIYCVRDYHTVFAPKCASCARPILPAQGCETTIRVVSMDRDYHVECY 349

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
Match: Ajuba (ajuba LIM protein [Source:MGI Symbol;Acc:MGI:1341886])

HSP 1 Score: 161.384 bits (407), Expect = 1.911e-45
Identity = 69/157 (43.95%), Postives = 107/157 (68.15%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C+  I    +ACQA+  L+H  CF CC C R L+ K FY  +G ++CEEDYL+ GFQ++A++C +CGH+I  KIL+A G  YH  CFRC +CN+CLDG PFT+D   ++ C+ DY+ +++  C +C QPI+P +      +V+ +++++HF C+
Sbjct:  347 CIKCNKGIYGQSNACQALDSLYHTQCFVCCSCGRTLRCKAFYSVNGSVYCEEDYLFSGFQEAAEKCCVCGHLILEKILQAMGKSYHPGCFRCIVCNKCLDGVPFTVDFSNQVYCVTDYHKNYAPKCAACGQPILPSEGCEDIVRVISMDRDYHFECY 503

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
Match: Lpp (LIM domain containing preferred translocation partner in lipoma [Source:MGI Symbol;Acc:MGI:2441849])

HSP 1 Score: 116.316 bits (290), Expect = 3.547e-29
Identity = 55/158 (34.81%), Postives = 87/158 (55.06%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C +C   +      C AM  +FH +CF+C  C  +L+G+ FY    K +CE  Y+      + ++C +C   I  +IL+A G  YH  CF C +C+  LDG PFT+D  G I CI+D++   +  C  C +PI+P      T ++V L+++FH  C++
Sbjct:  292 CARCGENVVGEGTGCTAMDQVFHVDCFTCIVCDVKLRGQPFYAVEKKAYCEPCYI-----NTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYR 444

HSP 2 Score: 48.521 bits (114), Expect = 5.176e-6
Identity = 38/115 (33.04%), Postives = 53/115 (46.09%), Query Frame = 2

Query:   47 INGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDH-GKLFCEEDYLYCGFQQSADRCKIC--------GHMITNKILKADGNYYHVDCFRCTICNECLD 364
            IN    C  CS  I   E   +A G  +H +CF+C  C+R L G  F  D  G + C ED+     ++ A RC +C        G   T +I+  D ++ HV C+RC  C   L 
Sbjct:  346 INTLEQCSVCSKPI--MERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDF----HKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDF-HVHCYRCEDCGGLLS 453

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
Match: Lpp (LIM domain containing preferred translocation partner in lipoma [Source:MGI Symbol;Acc:MGI:2441849])

HSP 1 Score: 115.161 bits (287), Expect = 1.564e-28
Identity = 55/158 (34.81%), Postives = 87/158 (55.06%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C +C   +      C AM  +FH +CF+C  C  +L+G+ FY    K +CE  Y+      + ++C +C   I  +IL+A G  YH  CF C +C+  LDG PFT+D  G I CI+D++   +  C  C +PI+P      T ++V L+++FH  C++
Sbjct:  417 CARCGENVVGEGTGCTAMDQVFHVDCFTCIVCDVKLRGQPFYAVEKKAYCEPCYI-----NTLEQCSVCSKPIMERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVHCYR 569

HSP 2 Score: 48.521 bits (114), Expect = 5.387e-6
Identity = 38/114 (33.33%), Postives = 53/114 (46.49%), Query Frame = 2

Query:   47 INGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDH-GKLFCEEDYLYCGFQQSADRCKIC--------GHMITNKILKADGNYYHVDCFRCTICNECL 361
            IN    C  CS  I   E   +A G  +H +CF+C  C+R L G  F  D  G + C ED+     ++ A RC +C        G   T +I+  D ++ HV C+RC  C   L
Sbjct:  471 INTLEQCSVCSKPI--MERILRATGKAYHPHCFTCVMCHRSLDGIPFTVDACGLIHCIEDF----HKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDF-HVHCYRCEDCGGLL 577

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
Match: sp|A9LS46|WTIP_XENLA (Wilms tumor protein 1-interacting protein homolog OS=Xenopus laevis OX=8355 GN=wtip PE=1 SV=1)

HSP 1 Score: 191.815 bits (486), Expect = 4.690e-55
Identity = 83/158 (52.53%), Postives = 113/158 (71.52%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+
Sbjct:  480 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECY 637

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
Match: sp|A8DZE6|WTIP_DANRE (Wilms tumor protein 1-interacting protein homolog OS=Danio rerio OX=7955 GN=wtip PE=3 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 1.186e-52
Identity = 81/158 (51.27%), Postives = 111/158 (70.25%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+A++C +CGH+I   IL+A G  YH  CFRC IC E LDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+
Sbjct:  438 ICVKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTAEKCFVCGHLIMEMILQALGRSYHPGCFRCVICKEGLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVDCY 595

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
Match: sp|Q9UGP4|LIMD1_HUMAN (LIM domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LIMD1 PE=1 SV=1)

HSP 1 Score: 185.267 bits (469), Expect = 1.223e-52
Identity = 82/157 (52.23%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +CS  +  A  ACQAMG L+H+ CF+C  C R+L+GK FY  +GK+FCEED+LY GFQQSADRC +CGH+I + IL+A G  YH  CFRC ICNECLDG PFT+D + KI C++DY+   +  C +C  PI+P + S  T +VV +++++H  C+
Sbjct:  472 CVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECY 628

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
Match: sp|G5E5X0|LIMD1_BOVIN (LIM domain-containing protein 1 OS=Bos taurus OX=9913 GN=LIMD1 PE=3 SV=1)

HSP 1 Score: 184.882 bits (468), Expect = 1.421e-52
Identity = 82/157 (52.23%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +CS  +  A  ACQAMG L+H+ CF+C  C R+L+GK FY  +GK+FCEED+LY GFQQSADRC +CGH+I + IL+A G  YH  CFRC ICNECLDG PFT+D + KI C++DY+   +  C +C  PI+P + S  T +VV +++++H  C+
Sbjct:  470 CVKCSKGVFGAGQACQAMGNLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECY 626

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
Match: sp|B5DEH0|LIMD1_RAT (LIM domain-containing protein 1 OS=Rattus norvegicus OX=10116 GN=Limd1 PE=1 SV=1)

HSP 1 Score: 184.111 bits (466), Expect = 2.208e-52
Identity = 82/157 (52.23%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +CS  +  A  ACQAMG L+H+ CF+C  C R+L+GK FY  +GK+FCEED+LY GFQQSADRC +CGH+I + IL+A G  YH  CFRC ICNECLDG PFT+D + KI C++DY+   +  C +C  PI+P + S  T +VV +++++H  C+
Sbjct:  459 CVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECY 615

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
Match: A0A091QPT6 (Wilms tumor protein 1-interacting protein (Fragment) OS=Mesitornis unicolor OX=54374 GN=N332_11393 PE=4 SV=1)

HSP 1 Score: 186.808 bits (473), Expect = 5.688e-56
Identity = 83/159 (52.20%), Postives = 113/159 (71.07%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+ 
Sbjct:    2 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYH 160

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
Match: A0A093EQS0 (Wilms tumor protein 1-interacting protein (Fragment) OS=Pterocles gutturalis OX=240206 GN=N339_02970 PE=4 SV=1)

HSP 1 Score: 186.808 bits (473), Expect = 5.688e-56
Identity = 83/159 (52.20%), Postives = 113/159 (71.07%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+ 
Sbjct:    2 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYH 160

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
Match: A0A091IHI8 (Wilms tumor protein 1-interacting protein (Fragment) OS=Calypte anna OX=9244 GN=N300_03377 PE=4 SV=1)

HSP 1 Score: 188.734 bits (478), Expect = 6.537e-56
Identity = 84/159 (52.83%), Postives = 114/159 (71.70%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+AD+C +CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D + KI C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+ 
Sbjct:    2 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCGHLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENKIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYH 160

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
Match: A0A4E0RNG9 (Wilms tumor protein 1-interacting protein OS=Fasciola hepatica OX=6192 GN=D915_006310 PE=4 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 9.137e-56
Identity = 85/157 (54.14%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C   I    DAC A+G L+HN+CF CCYC R L+GKIFYKD  K++CEEDYLYCGFQQ+ ++C +CGH+I+  IL+A GN YH  CFRC +C +CLDG PFT+D +  I C+ DY+L H+  C +C   IIPE+ S    +VV L+KEFH +C+
Sbjct:   94 CAECGLRIINLADACHALGYLYHNSCFVCCYCQRSLRGKIFYKDQDKIYCEEDYLYCGFQQTTEKCSVCGHLISETILQAMGNSYHPGCFRCCVCTKCLDGVPFTVDANKLIYCLPDYHLVHAPRCGACGLVIIPEEGSDEIVRVVALDKEFHLSCY 250

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
Match: A0A504YTW2 (Wilms tumor protein 1-interacting protein OS=Fasciola gigantica OX=46835 GN=FGIG_11222 PE=4 SV=1)

HSP 1 Score: 192.2 bits (487), Expect = 1.074e-55
Identity = 85/157 (54.14%), Postives = 112/157 (71.34%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C   I    DAC A+G L+HN+CF CCYC R L+GKIFYKD  K++CEEDYLYCGFQQ+ ++C +CGH+I+  IL+A GN YH  CFRC +C +CLDG PFT+D +  I C+ DY+L H+  C +C   IIPE+ S    +VV L+KEFH +C+
Sbjct:   94 CAECGLRIINLADACHALGYLYHNSCFVCCYCQRSLRGKIFYKDQDKIYCEEDYLYCGFQQTTEKCSVCGHLISETILQAMGNSYHPGCFRCCVCTKCLDGVPFTVDANKLIYCLPDYHLVHAPRCGACGLVIIPEEGSDEIVRVVALDKEFHLSCY 250

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
Match: LIMD1 (LIM domains containing 1 [Source:NCBI gene;Acc:103029777])

HSP 1 Score: 191.045 bits (484), Expect = 5.057e-56
Identity = 85/157 (54.14%), Postives = 113/157 (71.97%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +CS  +  A  ACQAMG L+H+NCF+C  C R+L+GK FY   GK+FCEED+LY GFQQSAD+C +CGH+I + IL+A G  YH  CFRC ICNE LDG PFT+D + KI C+KDY+   +  C +CNQPI+P + S  T +VV ++K++H  C+
Sbjct:  442 CVKCSKPVYGASQACQAMGSLYHDNCFTCSACSRKLRGKAFYYVCGKVFCEEDFLYSGFQQSADKCNVCGHLIMDMILQALGKSYHPGCFRCVICNESLDGVPFTVDTENKIYCVKDYHRVLAPKCAACNQPILPSEGSDETIRVVSMDKDYHVECY 598

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
Match: wtip (WT1 interacting protein [Source:NCBI gene;Acc:566046])

HSP 1 Score: 164.081 bits (414), Expect = 4.097e-46
Identity = 75/159 (47.17%), Postives = 103/159 (64.78%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK        Y GFQQ+A++C +CGH+I   IL+A G  YH  CFRC +C E LDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+ 
Sbjct:  430 ICVKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGK--------YSGFQQTAEKCFVCGHLIMEMILQALGKSYHPSCFRCVVCKEGLDGVPFTVDMENNIYCVKDYHTVFAPKCASCNQPILPAEGSEETIRVVSMDKDYHVECYH 580

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
Match: ajuba (ajuba LIM protein [Source:NCBI gene;Acc:103024444])

HSP 1 Score: 160.614 bits (405), Expect = 1.267e-44
Identity = 68/157 (43.31%), Postives = 104/157 (66.24%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C   +  A++ACQA+  L+H  CF+C  C R L+ K FY   G ++C+EDY++ GFQ +A++C +CGH+I  +IL+A GN YH  CFRCT+C++ LDG PFT+D    + C+ DY  + +  C +C QPI+P + S    +VV + K++HF C+
Sbjct:  489 CVKCGKGVYGADNACQALDSLYHTRCFTCVSCGRTLRNKDFYNVSGSVYCKEDYMFSGFQAAAEKCSVCGHLILEQILQALGNSYHPGCFRCTVCSKTLDGVPFTVDYLNNVYCVSDYNRTFAPKCAACLQPILPTEGSEEILRVVSMNKDYHFECY 645

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
Match: LIMD1 (LIM domains containing 1 [Source:NCBI gene;Acc:103029777])

HSP 1 Score: 154.836 bits (390), Expect = 8.319e-43
Identity = 68/124 (54.84%), Postives = 91/124 (73.39%), Query Frame = 2

Query:  164 RQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            R+L+GK FY   GK+FCEED+LY GFQQSAD+C +CGH+I + IL+A G  YH  CFRC ICNE LDG PFT+D + KI C+KDY+   +  C +CNQPI+P + S  T +VV ++K++H  C+
Sbjct:  441 RKLRGKAFYYVCGKVFCEEDFLYSGFQQSADKCNVCGHLIMDMILQALGKSYHPGCFRCVICNESLDGVPFTVDTENKIYCVKDYHRVLAPKCAACNQPILPSEGSDETIRVVSMDKDYHVECY 564

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
Match: zyx (zyxin [Source:NCBI gene;Acc:103029170])

HSP 1 Score: 132.88 bits (333), Expect = 6.980e-35
Identity = 67/159 (42.14%), Postives = 93/159 (58.49%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +++++ A +AM  LFH++CF C  C R L+G  FY   G   CEE Y++     S   C  CG  IT+++LKA G  +H  CFRCT C   L+GAPF  D D    C+ DY+   S  C SCN+PI+P+  S  T +VV LEK FH  C++
Sbjct:  397 VCGKCKEGLSRSQPAVRAMDKLFHSHCFCCVTCQRPLQGMQFYDRDGTPECEECYVH-----SLAICSRCGERITDRVLKAVGQCFHAHCFRCTACKCTLEGAPFITDDDNNPFCVPDYHRRFSPLCVSCNEPIVPDPGSEETVRVVALEKNFHLKCYR 550

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010404.1 (pep scaffold:Pmarinus_7.0:GL477924:140:5584:1 gene:ENSPMAG00000009420.1 transcript:ENSPMAT00000010404.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 102.064 bits (253), Expect = 1.829e-27
Identity = 42/84 (50.00%), Postives = 60/84 (71.43%), Query Frame = 2

Query:  230 YCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNS 481
            Y GFQQ+AD+C  CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D+D ++ C++DY+ + +  C +C  PI+P ++ 
Sbjct:    1 YSGFQQNADKCFECGHLIMETILQAVGKSYHPTCFRCVVCNECLDGVPFTVDRDHRVYCVQDYHRTFAPKCAACGLPILPNQSG 84

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010401.1 (pep scaffold:Pmarinus_7.0:GL477924:137:5584:1 gene:ENSPMAG00000009420.1 transcript:ENSPMAT00000010401.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 100.523 bits (249), Expect = 8.009e-27
Identity = 46/103 (44.66%), Postives = 64/103 (62.14%), Query Frame = 2

Query:  230 YCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYY-LSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            Y GFQQ+AD+C  CGH+I   IL+A G  YH  CFRC +CNECLDG PFT+D+D ++ C++DY+  + +  C +C  PI+P +      KV V  +     C 
Sbjct:    2 YSGFQQNADKCFECGHLIMETILQAVGKSYHPTCFRCVVCNECLDGVPFTVDRDHRVYCVQDYHRRTFAPKCAACGLPILPNQGKYIRVKVRVFVEIIDIDCM 104

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
Match: lims2 (LIM and senescent cell antigen-like domains 2 [Source:ZFIN;Acc:ZDB-GENE-050522-56])

HSP 1 Score: 60.8474 bits (146), Expect = 4.433e-11
Identity = 41/136 (30.15%), Postives = 60/136 (44.12%), Query Frame = 2

Query:   11 KSICSLFMSFNSI----NGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILC 406
            K  C  +   N      N +   C+     +  E    + G LFH NCF C  C++Q      Y+  G+ +CE D+        A  C   G  I  +++KA  N +H +CFRC IC+E L    F +   G+ LC
Sbjct:   57 KEFCDFYAKLNMASALANAACERCKAGFPPSATERIVNSNGELFHENCFVCAQCFQQF----LYEFEGRKYCEHDFQML----FAPCCGQSGEFIVGRVIKAMNNSWHPECFRCNICSEMLADVGF-VKNAGRHLC 183

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
Match: PXN (paxillin [Source:HGNC Symbol;Acc:HGNC:9718])

HSP 1 Score: 58.151 bits (139), Expect = 1.776e-10
Identity = 40/143 (27.97%), Postives = 66/143 (46.15%), Query Frame = 2

Query:  113 AMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITN--KILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            AMG  +H   F C +C  ++  + F++  G+ +CEEDY        + RC  C   + +  +++ A    +H + F C  C        F  ++DGK  C +DYY   +  C  C++ I+  +N LS    V     +H  CF
Sbjct:    5 AMGRTWHPEHFVCVHCQVEIGSRNFFEKDGQPYCEEDY----HSLFSPRCAYCNEAVMDNQRVVTALDRTWHPEHFFCAQCGRPFGEEGFH-ERDGKPYCRQDYYGMFAPKCNGCSRAIM--QNYLSALNTV-----WHPECF 135

HSP 2 Score: 55.4546 bits (132), Expect = 1.472e-9
Identity = 41/160 (25.62%), Postives = 65/160 (40.62%), Query Frame = 2

Query:   56 SVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFT----LDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFH 523
            S  C  C+  +   +    A+   +H   F C  C R    + F++  GK +C +DY    +   A +C  C   I    L A    +H +CF   IC EC    PF      + +G+  C   Y+    S C  C +PI       + + +  + K+FH
Sbjct:   47 SPRCAYCNEAVMDNQRVVTALDRTWHPEHFFCAQCGRPFGEEGFHERDGKPYCRQDY----YGMFAPKCNGCSRAIMQNYLSALNTVWHPECF---ICRECF--TPFINGSFFEHEGQPYCEVHYHERRGSLCSGCQKPI-------TGRCISAMAKKFH 190

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
Match: PXN (paxillin [Source:HGNC Symbol;Acc:HGNC:9718])

HSP 1 Score: 59.3066 bits (142), Expect = 2.774e-10
Identity = 41/147 (27.89%), Postives = 66/147 (44.90%), Query Frame = 2

Query:   95 AEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            A     AMG  +H   F C  C  ++  + F++  G  +CE+DY +      + RC  C   I +K++ A    +H + F C  C        F  +KDGK  C +DY+   +  C  C++ I+  +N +S      L   +H  CF
Sbjct:  330 AGQVVTAMGRTWHPEHFVCTECQEEIGARNFFERDGLPYCEKDYHFL----FSPRCAYCSGPILDKVVTALDKTWHPEHFFCVQCGHFFGDEGFH-EKDGKPYCRQDYFEMFAPKCGGCSRAIV--ENYIS-----ALSALWHPECF 464

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Yeast
Match: RGA2 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p; RGA2 has a paralog, RGA1, that arose from the whole genome duplication [Source:SGD;Acc:S000002787])

HSP 1 Score: 46.2098 bits (108), Expect = 3.346e-6
Identity = 38/133 (28.57%), Postives = 57/133 (42.86%), Query Frame = 2

Query:   32 MSFNSING-SVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGK--IFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMI--TNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKD 415
            MS + IN  S LC +C+  I  ++   +     +H+ CF+C  C ++L         D G L C +          +D+C  CG  I  T  IL +    Y  +CFRC  C+  +    +   K G  LC  D
Sbjct:    1 MSADPINDQSSLCVRCNKSIASSQ-VYELESKKWHDQCFTCYKCDKKLNADSDFLVLDIGTLICYD---------CSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNRIKNLKYAKTKRG--LCCMD 121

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Yeast
Match: RGA1 (GTPase-activating protein for polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; relocalizes from bud neck to cytoplasm upon DNA replication stress; RGA1 has a paralog, RGA2, that arose from the whole genome duplication [Source:SGD;Acc:S000005653])

HSP 1 Score: 45.8246 bits (107), Expect = 4.697e-6
Identity = 46/175 (26.29%), Postives = 63/175 (36.00%), Query Frame = 2

Query:   65 CCQCSGLINKA---EDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQ-----QSADRCKICGHMITNK--ILKADGNYYHVDCFRCTICNECLDGAPFTLDKDG--------KILCIKDYYLSH----SSNCESCNQPIIPEKNSLSTKKVVVL-EKEF 520
            C +C   I      E  C      +H +CF+C  C + L             CE D+L  G         +D CK CG  I +   IL +    Y  DCF+C  C E +    +   K G        K+L  + YY         N  S   P+I   ++       VL EK F
Sbjct:   13 CVRCKEFITTGHAYELGCDR----WHTHCFACYKCEKPLS------------CESDFLVLGTGALICFDCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAKRKYYEEKKRRLKKNLPSLPTPVIDNGHTDEVSASAVLPEKTF 171

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BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
Match: EDO39581 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S9J0])

HSP 1 Score: 124.02 bits (310), Expect = 2.058e-34
Identity = 65/159 (40.88%), Postives = 90/159 (56.60%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   ++     C AM  LFH  CF C  C  QL GK+FYK     +CE DYL      S + C  C   IT++IL+A G  +H  CF C  C++ LDG PFTLD   K+ C++DYY  +S  C SC+Q I+PE     T ++V + K+FH  C++
Sbjct:   35 MCSKCGQKVSGEGTGCTAMDKLFHIKCFICVKCGCQLTGKVFYKVDNDAYCEADYL-----DSLETCWYCHQHITDRILRATGKCFHPHCFNCEECHKNLDGVPFTLDNFNKVHCLEDYYRKYSPRCASCHQLILPEDGQDETVRIVSMNKDFHVRCYK 188

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
Match: EDO32541 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUS6])

HSP 1 Score: 120.939 bits (302), Expect = 3.503e-34
Identity = 57/141 (40.43%), Postives = 84/141 (59.57%), Query Frame = 2

Query:  116 MGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            MG L+H  CF C  C ++L+G+ FY+   +++C++DY      Q   RC  C  +I  +IL+  G  YH  CFRC +C   L+G PFT+D+   I CI DY+  +S  C +C +PI P++ S  T +VV L K+FH  CF+
Sbjct:    1 MGNLYHAQCFLCHTCGKELRGQEFYRLENRVYCKQDYKSLERHQRPKRCHSCKEVIGQRILQTLGRDYHPVCFRCCVCEVELEGTPFTVDRQNAIYCIPDYHRKYSPRCHACREPIAPDEKSDETIRVVCLGKQFHDRCFK 141

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
Match: EDO41181 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S548])

HSP 1 Score: 69.3218 bits (168), Expect = 6.471e-14
Identity = 46/157 (29.30%), Postives = 70/157 (44.59%), Query Frame = 2

Query:   56 SVLCCQCSGLINKAEDAC-QAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFH 523
            +  C  C+G I    D+C  A+   +H   F C  C        F++  GK FC EDY    +   A RC  CG  I +  + A   ++H +CF CT C +   G  F  D DG+  C   Y+    + C SC +PI       + + +  + ++FH
Sbjct:   82 APRCAYCNGPI---LDSCVTALDQTWHPEHFVCAECGNPFGDTGFHERDGKPFCREDY----YAMFAPRCGGCGQPIMDNYISALSAHWHAECFICTECRQPFPGGSF-FDHDGRPYCEMHYHAKRGTLCYSCQKPI-------TGRCITAMHRKFH 223

HSP 2 Score: 65.855 bits (159), Expect = 1.077e-12
Identity = 46/164 (28.05%), Postives = 66/164 (40.24%), Query Frame = 2

Query:   44 SINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            S     +C  C+  I      C A+G  +H   F+C  C   L  + F++  GK +CE DY        A RC  C   I +  + A    +H + F C  C        F  ++DGK  C +DYY   +  C  C QPI+          +  L   +H  CF
Sbjct:   19 STTKKGMCAACNKPI--IGQVCTALGKTWHPEHFACVACEAPLGTQNFFERDGKPYCERDY----HDTFAPRCAYCNGPILDSCVTALDQTWHPEHFVCAECGNPFGDTGFH-ERDGKPFCREDYYAMFAPRCGGCGQPIM-------DNYISALSAHWHAECF 168

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
Match: EDO47660 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RLT9])

HSP 1 Score: 69.3218 bits (168), Expect = 1.232e-13
Identity = 39/119 (32.77%), Postives = 57/119 (47.90%), Query Frame = 2

Query:   56 SVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIK 412
            + +C  C       E    + G + H  CF C  C++     +FY+  G+ FCE D+        A  CK CG  +  +++KA    +H DCFRC ICN+CL    F +   G+ LC K
Sbjct:   18 TAICAVCHEGFGVDERMVNSNGQILHERCFVCVQCFQAFPDGLFYEYDGRRFCEHDFQ----TLFAPCCKQCGKFVIGRVIKAMQANWHPDCFRCEICNDCLADTGF-VKNAGRALCKK 131

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
Match: LIMPET (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFX6])

HSP 1 Score: 65.4698 bits (158), Expect = 3.479e-12
Identity = 48/165 (29.09%), Postives = 73/165 (44.24%), Query Frame = 2

Query:   41 NSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
              IN S +C  C+G     E         FH+ CF C  C + +  K F +   +  C      C   + A  C  C  +I    ++  G+ YH +CF C  C++ L G+PFT  ++G+ +C   Y   ++  C +C+  I       +TK V   EK FH  CF
Sbjct:  371 RGINPSKVCAACNGDFAPGEKKVGYQSKTFHDKCFICDECKQPIGSKQFIRRDERRLCNN----CFDSKFAKVCVKCNQVIKTSSVQHAGSTYHSECFTCHHCDKPLAGSPFT-KQEGRNVCQNCYRERYAKRCGACHNLI-----EGNTKFVAYDEKYFHRECF 525

HSP 2 Score: 61.2326 bits (147), Expect = 1.059e-10
Identity = 37/118 (31.36%), Postives = 63/118 (53.39%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMI--TNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCI 409
            +C +C+ +I  +  + Q  G  +H+ CF+C +C + L G  F K  G+  C+     C  ++ A RC  C ++I    K +  D  Y+H +CF C  CN+ L G  F + +DG+ +C+
Sbjct:  439 VCVKCNQVIKTS--SVQHAGSTYHSECFTCHHCDKPLAGSPFTKQEGRNVCQN----CYRERYAKRCGACHNLIEGNTKFVAYDEKYFHRECFTCCKCNKPLAGEKFRI-RDGEKICL 549

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Medaka
Match: LIMD1 (LIM domains containing 1 [Source:NCBI gene;Acc:101175430])

HSP 1 Score: 190.274 bits (482), Expect = 2.007e-56
Identity = 83/158 (52.53%), Postives = 113/158 (71.52%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            +C +C+  +  A  ACQAMG L+H++CF+C  C R+L+GK FY   GK+FCEED+LY GFQQSAD+C  CGH+I + IL+A G  YH  CFRC ICNE LDG PFT+D + KI C++DY+   +  C +CNQPI+P + S  T +VV +EK++H  C+
Sbjct:  337 VCVRCNTAVYGASQACQAMGSLYHDSCFTCTACSRRLRGKAFYYVGGKVFCEEDFLYSGFQQSADKCNACGHLIMDMILQALGKSYHPGCFRCVICNESLDGVPFTVDTENKIYCVRDYHRVLAPKCAACNQPILPSEGSDETIRVVSMEKDYHVECY 494

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Medaka
Match: wtip (WT1 interacting protein [Source:NCBI gene;Acc:101158185])

HSP 1 Score: 187.578 bits (475), Expect = 1.412e-54
Identity = 81/159 (50.94%), Postives = 112/159 (70.44%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+A++C +CGH+I   IL+A G  YH  CFRC +C E LDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+Q
Sbjct:  489 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTAEKCFVCGHLIMEMILQALGKSYHPGCFRCVVCKEGLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYQ 647

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Medaka
Match: wtip (WT1 interacting protein [Source:NCBI gene;Acc:101158185])

HSP 1 Score: 187.193 bits (474), Expect = 3.328e-54
Identity = 81/159 (50.94%), Postives = 112/159 (70.44%), Query Frame = 2

Query:   62 LCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            +C +C   +  A  ACQAMG L+H NCF+CC C R+L+GK FY  +GK++CEED+LY GFQQ+A++C +CGH+I   IL+A G  YH  CFRC +C E LDG PFT+D +  I C+KDY+   +  C SCNQPI+P + S  T +VV ++K++H  C+Q
Sbjct:  489 ICIKCGKGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTAEKCFVCGHLIMEMILQALGKSYHPGCFRCVVCKEGLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILPAQGSEETIRVVSMDKDYHVECYQ 647

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Medaka
Match: ajuba (ajuba LIM protein [Source:NCBI gene;Acc:100529186])

HSP 1 Score: 159.844 bits (403), Expect = 2.441e-44
Identity = 68/157 (43.31%), Postives = 104/157 (66.24%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C   +  A++ACQA   L+H  CF+C  C R L+ K FY  +G ++C+EDY++ GFQ +A++C +CGH+I  +IL+A GN YH  CFRC +C++ LDG PFT+D+   I C+ DY  + +  C +C QPI+P + S    +VV + K++HF C+
Sbjct:  492 CVKCGKGVYGADNACQAQENLYHTRCFTCVSCGRTLRNKDFYNVNGSVYCKEDYMFSGFQAAAEKCTVCGHLILEQILQALGNSYHPGCFRCVVCSKALDGVPFTVDQHSNIYCVADYNKTFAPKCAACLQPILPTEGSEEILRVVSMNKDYHFECY 648

[Close]

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACF 535
            C +C   +  A++ACQA   L+H  CF+C  C R L+ K FY  +G ++C+EDY++ GFQ +A++C +CGH+I  +IL+A GN YH  CFRC +C++ LDG PFT+D+   I C+ DY  + +  C +C QPI+P + S    +VV + K++HF C+
Sbjct:  492 CVKCGKGVYGADNACQAQENLYHTRCFTCVSCGRTLRNKDFYNVNGSVYCKEDYMFSGFQAAAEKCTVCGHLILEQILQALGNSYHPGCFRCVVCSKALDGVPFTVDQHSNIYCVADYNKTFAPKCAACLQPILPTEGSEEILRVVSMNKDYHFECY 648

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST
Match: SMESG000031934.1 (SMESG000031934.1)

HSP 1 Score: 348.977 bits (894), Expect = 3.459e-131
Identity = 169/169 (100.00%), Postives = 169/169 (100.00%), Query Frame = 2

Query:   32 MSFNSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            MSFNSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ
Sbjct:    1 MSFNSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 169

HSP 2 Score: 83.5741 bits (205), Expect = 3.459e-131
Identity = 38/38 (100.00%), Postives = 38/38 (100.00%), Query Frame = 3

Query:  540 ECQMNLTIESDSSCYPKYDSVGNLHLYCRRCFVKSPHI 653
            ECQMNLTIESDSSCYPKYDSVGNLHLYCRRCFVKSPHI
Sbjct:  172 ECQMNLTIESDSSCYPKYDSVGNLHLYCRRCFVKSPHI 209

HSP 3 Score: 77.411 bits (189), Expect = 3.459e-131
Identity = 36/36 (100.00%), Postives = 36/36 (100.00%), Query Frame = 1

Query:  676 PPLRLSHQQILRNFKVLQKSLRHSDKETINLIYATQ 783
            PPLRLSHQQILRNFKVLQKSLRHSDKETINLIYATQ
Sbjct:  217 PPLRLSHQQILRNFKVLQKSLRHSDKETINLIYATQ 252

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST
Match: SMESG000038145.1 (SMESG000038145.1)

HSP 1 Score: 168.703 bits (426), Expect = 1.651e-49
Identity = 75/158 (47.47%), Postives = 110/158 (69.62%), Query Frame = 2

Query:   65 CCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFACFQ 538
            C +C  LI  +E AC A+G L+H+NCF+CCYC R L+G++FYKD  K++CE DY+  GF +S   C  CGH++T  IL+A G  +H  CF+C+IC++CLDG PFT+D++  I CI DY+ + +  C  C QPIIP K+S    ++VV +++FH  C++
Sbjct:  204 CNKCQCLITDSEGACIALGNLYHSNCFTCCYCNRSLRGRVFYKDQEKIYCENDYMVFGFHKSVKVCFACGHIVTETILEALGKDFHPRCFKCSICHKCLDGIPFTVDRNNNIYCIIDYHNTFAPRCAICLQPIIPRKDSDEVVRIVVNDRDFHVECYR 361

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST
Match: SMESG000031084.1 (SMESG000031084.1)

HSP 1 Score: 95.5153 bits (236), Expect = 1.701e-22
Identity = 50/165 (30.30%), Postives = 84/165 (50.91%), Query Frame = 2

Query:   38 FNSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTKKVVVLEKEFHFAC 532
            F   NG     Q +G +N           +FH  CF+C  C   L    F+    +L C      C   +S ++C +C  +I ++I++  G+ YH  CF CT+CN CLDG  FT+D   ++ C++D++  ++  C++C +PI P+      K+++  +K FH  C
Sbjct:  205 FELANGKSSVGQINGPLN----------TVFHQTCFNCYRCEANLNVDSFFYAQKRLLCSR----C-VHESLEKCTVCNFIINDRIIRVLGHPYHPKCFTCTVCNCCLDGKAFTVDVHERMFCLEDFHKRYAPRCDACGEPIRPQNGGQENKRIISGDKTFHLEC 354

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST
Match: SMESG000011768.1 (SMESG000011768.1)

HSP 1 Score: 66.2402 bits (160), Expect = 2.732e-12
Identity = 39/122 (31.97%), Postives = 57/122 (46.72%), Query Frame = 2

Query:   41 NSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILC 406
            N I+    C  C G     E   Q     +H +CF C  C++     IFY+   K +CE D+        A  C  CG  I  +++KA G+ +H DCFRC +C+  L  + F  +  G+ LC
Sbjct:   39 NKISDGSFCYHCDGPFELNEKVVQVGDYQWHTSCFVCAQCFQTFPNGIFYEFGDKKYCEHDFHVL----FAPCCGSCGEFIIGRVIKAMGSNWHADCFRCQLCSVVLSDSGFVKNL-GRALC 155

[Close]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST
Match: SMESG000077137.1 (SMESG000077137.1)

HSP 1 Score: 57.7658 bits (138), Expect = 6.021e-10
Identity = 41/148 (27.70%), Postives = 65/148 (43.92%), Query Frame = 2

Query:   56 SVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGKIFYKDHGKLFCEE--DYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDCFRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNSLSTK 493
            +  C +C+  I   + A  AM  +FH  CF C  C +++ G +F    GK  C++  +      Q++A  C  C   I  + L A    +H++CF CT C   +    F + K+G   CI  Y    +  C  C   I P +  L  +
Sbjct:    2 TTTCSKCNKEILPGQTALSAMEKVFHKECFVCSGCKKEMGGTMFKVVEGKNICDDCFNKKKAEQQKAAGVCGKCNLDIKGQFLGALDKKFHLECFICTKCGTNISRTSFQV-KEGSAYCIDCYTELFAPKCFVCETMIKPTEPYLEVE 148

The following BLAST results are available for this feature:

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Celegans
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Zebrafish
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Yeast
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Medaka
BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
WTIP	2.897e-54	47.80	WT1 interacting protein [Source:HGNC Symbol;Acc:HG...	[more]
LIMD1	2.547e-53	52.23	LIM domains containing 1 [Source:HGNC Symbol;Acc:H...	[more]
WTIP	1.522e-52	48.10	WT1 interacting protein [Source:HGNC Symbol;Acc:HG...	[more]
LIMD1	3.042e-48	55.47	LIM domains containing 1 [Source:HGNC Symbol;Acc:H...	[more]
AJUBA	4.793e-45	43.95	ajuba LIM protein [Source:HGNC Symbol;Acc:HGNC:202...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5


Match Name	E-value	Identity	Description
zyx-1	4.777e-31	36.48	Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4]	[more]
zyx-1	1.374e-30	36.48	Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4]	[more]
zyx-1	1.520e-29	36.48	Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4]	[more]
zyx-1	9.719e-28	36.25	Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4]	[more]
zyx-1	9.719e-28	36.25	Zyxin [Source:UniProtKB/Swiss-Prot;Acc:Q9U3F4]	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
jub	3.583e-52	51.27	gene:FBgn0030530 transcript:FBtr0340292	[more]
jub	3.583e-52	51.27	gene:FBgn0030530 transcript:FBtr0303418	[more]
jub	4.062e-52	51.27	gene:FBgn0030530 transcript:FBtr0073834	[more]
jub	7.203e-50	49.69	gene:FBgn0030530 transcript:FBtr0303419	[more]
Zyx	1.688e-29	36.71	gene:FBgn0011642 transcript:FBtr0309882	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
wtip	1.571e-53	51.27	WT1 interacting protein [Source:NCBI gene;Acc:5660...	[more]
ajuba	4.904e-45	43.31	ajuba LIM protein [Source:ZFIN;Acc:ZDB-GENE-030131...	[more]
zyx	4.527e-36	44.03	zyxin [Source:ZFIN;Acc:ZDB-GENE-070928-18]	[more]
zyx	4.527e-36	44.03	zyxin [Source:ZFIN;Acc:ZDB-GENE-070928-18]	[more]
lpp	2.108e-29	36.08	LIM domain containing preferred translocation part...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
arf4	1.059e-55	52.53	ADP ribosylation factor 4 [Source:Xenbase;Acc:XB-G...	[more]
arf4	3.074e-55	52.53	ADP ribosylation factor 4 [Source:Xenbase;Acc:XB-G...	[more]
gnpda1	2.611e-51	50.63	glucosamine-6-phosphate deaminase 1 [Source:Xenbas...	[more]
arf4	6.581e-43	52.76	ADP ribosylation factor 4 [Source:Xenbase;Acc:XB-G...	[more]
nudt17	6.825e-32	35.44	nudix hydrolase 17 [Source:Xenbase;Acc:XB-GENE-979...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Limd1	4.036e-53	52.23	LIM domains containing 1 [Source:MGI Symbol;Acc:MG...	[more]
Wtip	6.011e-52	48.10	WT1-interacting protein [Source:MGI Symbol;Acc:MGI...	[more]
Ajuba	1.911e-45	43.95	ajuba LIM protein [Source:MGI Symbol;Acc:MGI:13418...	[more]
Lpp	3.547e-29	34.81	LIM domain containing preferred translocation part...	[more]
Lpp	1.564e-28	34.81	LIM domain containing preferred translocation part...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|A9LS46\|WTIP_XENLA	4.690e-55	52.53	Wilms tumor protein 1-interacting protein homolog ...	[more]
sp\|A8DZE6\|WTIP_DANRE	1.186e-52	51.27	Wilms tumor protein 1-interacting protein homolog ...	[more]
sp\|Q9UGP4\|LIMD1_HUMAN	1.223e-52	52.23	LIM domain-containing protein 1 OS=Homo sapiens OX...	[more]
sp\|G5E5X0\|LIMD1_BOVIN	1.421e-52	52.23	LIM domain-containing protein 1 OS=Bos taurus OX=9...	[more]
sp\|B5DEH0\|LIMD1_RAT	2.208e-52	52.23	LIM domain-containing protein 1 OS=Rattus norvegic...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A091QPT6	5.688e-56	52.20	Wilms tumor protein 1-interacting protein (Fragmen...	[more]
A0A093EQS0	5.688e-56	52.20	Wilms tumor protein 1-interacting protein (Fragmen...	[more]
A0A091IHI8	6.537e-56	52.83	Wilms tumor protein 1-interacting protein (Fragmen...	[more]
A0A4E0RNG9	9.137e-56	54.14	Wilms tumor protein 1-interacting protein OS=Fasci...	[more]
A0A504YTW2	1.074e-55	54.14	Wilms tumor protein 1-interacting protein OS=Fasci...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LIMD1	5.057e-56	54.14	LIM domains containing 1 [Source:NCBI gene;Acc:103...	[more]
wtip	4.097e-46	47.17	WT1 interacting protein [Source:NCBI gene;Acc:5660...	[more]
ajuba	1.267e-44	43.31	ajuba LIM protein [Source:NCBI gene;Acc:103024444]	[more]
LIMD1	8.319e-43	54.84	LIM domains containing 1 [Source:NCBI gene;Acc:103...	[more]
zyx	6.980e-35	42.14	zyxin [Source:NCBI gene;Acc:103029170]	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ENSPMAT00000010404.1	1.829e-27	50.00	pep scaffold:Pmarinus_7.0:GL477924:140:5584:1 gene...	[more]
ENSPMAT00000010401.1	8.009e-27	44.66	pep scaffold:Pmarinus_7.0:GL477924:137:5584:1 gene...	[more]
lims2	4.433e-11	30.15	LIM and senescent cell antigen-like domains 2 [Sou...	[more]
PXN	1.776e-10	27.97	paxillin [Source:HGNC Symbol;Acc:HGNC:9718]	[more]
PXN	2.774e-10	27.89	paxillin [Source:HGNC Symbol;Acc:HGNC:9718]	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
RGA2	3.346e-6	28.57	GTPase-activating protein for polarity-establishme...	[more]
RGA1	4.697e-6	26.29	GTPase-activating protein for polarity-establishme...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5


Match Name	E-value	Identity	Description
EDO39581	2.058e-34	40.88	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO32541	3.503e-34	40.43	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO41181	6.471e-14	29.30	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO47660	1.232e-13	32.77	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
LIMPET	3.479e-12	29.09	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
LIMD1	2.007e-56	52.53	LIM domains containing 1 [Source:NCBI gene;Acc:101...	[more]
wtip	1.412e-54	50.94	WT1 interacting protein [Source:NCBI gene;Acc:1011...	[more]
wtip	3.328e-54	50.94	WT1 interacting protein [Source:NCBI gene;Acc:1011...	[more]
ajuba	2.441e-44	43.31	ajuba LIM protein [Source:NCBI gene;Acc:100529186]	[more]
ajuba	2.441e-44	43.31	ajuba LIM protein [Source:NCBI gene;Acc:100529186]	[more]

BLAST of Wilms tumor protein 1-interacting protein homolog vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000031934.1	3.459e-131	100.00	SMESG000031934.1	[more]
SMESG000038145.1	1.651e-49	47.47	SMESG000038145.1	[more]
SMESG000031084.1	1.701e-22	30.30	SMESG000031084.1	[more]
SMESG000011768.1	2.732e-12	31.97	SMESG000011768.1	[more]
SMESG000077137.1	6.021e-10	27.70	SMESG000077137.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30035262 ID=SMED30035262|Name=Wilms tumor protein 1-interacting protein homolog|organism=Schmidtea mediterranea sexual|type=transcript|length=830bp
TTAAAATGGGAAATCGATTTGTTCATTATTCATGTCTTTCAATTCGATAA
ACGGTTCGGTTCTCTGTTGTCAATGTTCCGGATTAATTAACAAAGCCGAA
GATGCCTGTCAAGCAATGGGAATGTTATTCCATAATAATTGTTTCTCTTG
CTGTTATTGTTATAGACAGCTGAAAGGGAAAATCTTCTATAAGGATCATG
GAAAGCTTTTCTGTGAAGAAGATTATTTGTATTGCGGTTTTCAACAAAGC
GCAGATCGTTGCAAAATCTGTGGACATATGATAACCAACAAGATTCTTAA
GGCTGATGGAAATTATTACCATGTTGATTGCTTTCGTTGCACAATATGTA
ATGAGTGCCTTGACGGAGCACCATTCACGTTGGATAAAGATGGAAAAATT
CTTTGCATAAAAGACTATTATTTATCGCATTCATCAAATTGTGAGTCTTG
CAATCAACCTATCATTCCTGAAAAGAATTCACTATCTACTAAAAAGGTTG
TTGTACTTGAAAAAGAGTTTCATTTTGCCTGCTTTCAATGAATGTCAAAT
GAATTTAACTATAGAGTCCGATTCATCATGTTATCCCAAATATGACAGCG
TTGGAAACCTTCATCTTTACTGTAGGAGATGTTTTGTCAAATCACCTCAC
ATTTCAAGAAGCTTGACATCTTCTTCCTCCTCTTCGTCTCTCGCATCAAC
AAATCCTAAGAAATTTCAAAGTTCTACAAAAGTCACTTCGACATTCAGAT
AAAGAGACGATAAATTTAATTTATGCAACTCAAAAAACTTTATCTTATTC
TTATTGAAATCTGCCAACTAAATACTGGAG

protein sequence of SMED30035262-orf-1

>SMED30035262-orf-1 ID=SMED30035262-orf-1|Name=SMED30035262-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=170bp
MSFNSINGSVLCCQCSGLINKAEDACQAMGMLFHNNCFSCCYCYRQLKGK
IFYKDHGKLFCEEDYLYCGFQQSADRCKICGHMITNKILKADGNYYHVDC
FRCTICNECLDGAPFTLDKDGKILCIKDYYLSHSSNCESCNQPIIPEKNS
LSTKKVVVLEKEFHFACFQ*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0030030	cell projection organization
GO:0045892	negative regulation of transcription, DNA-templated
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0007010	cytoskeleton organization
GO:0014032	neural crest cell development
GO:0022604	regulation of cell morphogenesis
GO:1903507	negative regulation of nucleic acid-templated transcription

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000101	muscle cell
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR028734	LIMD1
IPR001781	Znf_LIM

Vocabulary: **molecular function**
Term	Definition
GO:0008270	zinc ion binding
GO:0003714	transcription corepressor activity
GO:0046872	metal ion binding

Vocabulary: **cellular component**
Term	Definition
GO:0005634	nucleus
GO:0005912	adherens junction
GO:0030054	cell junction

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001781	Zinc finger, LIM-type	SMART	SM00132	lim_4	coord: 11..64 e-value: 1.1E-8 score: 44.9 coord: 76..128 e-value: 5.2E-14 score: 62.5
IPR001781	Zinc finger, LIM-type	PFAM	PF00412	LIM	coord: 77..130 e-value: 7.0E-11 score: 42.2 coord: 12..66 e-value: 2.4E-8 score: 34.1
IPR001781	Zinc finger, LIM-type	PROSITE	PS00478	LIM_DOMAIN_1	coord: 12..47
IPR001781	Zinc finger, LIM-type	PROSITE	PS00478	LIM_DOMAIN_1	coord: 77..110
IPR001781	Zinc finger, LIM-type	PROSITE	PS50023	LIM_DOMAIN_2	coord: 10..71 score: 11.801
IPR001781	Zinc finger, LIM-type	PROSITE	PS50023	LIM_DOMAIN_2	coord: 75..135 score: 12.939
None	No IPR available	GENE3D	G3DSA:2.10.110.10		coord: 3..68 e-value: 2.1E-12 score: 48.6
None	No IPR available	GENE3D	G3DSA:2.10.110.10		coord: 69..169 e-value: 7.3E-21 score: 76.5
None	No IPR available	PANTHER	PTHR24219	FAMILY NOT NAMED	coord: 11..169
None	No IPR available	SUPERFAMILY	SSF57716	Glucocorticoid receptor-like (DNA-binding domain)	coord: 102..168
None	No IPR available	SUPERFAMILY	SSF57716	Glucocorticoid receptor-like (DNA-binding domain)	coord: 40..106
IPR028734	LIM domain-containing protein 1	PANTHER	PTHR24219:SF3	LIM DOMAIN-CONTAINING PROTEIN 1	coord: 11..169