ORM1-like protein

Overview


Name	ORM1-like protein
Smed ID	SMED30035214
Length (bp)	831

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of ORM1-like protein (SMED30035214) t-SNE clustered cells

Violin plots show distribution of expression levels for ORM1-like protein (SMED30035214) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of ORM1-like protein (SMED30035214) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for ORM1-like protein (SMED30035214) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30035214

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
intestinal phagocyte	SMED30035214	SMESG000057003.1	Contig2851	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30035214	SMESG000057003.1	Contig2851	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30035214	SMESG000014644.1	Contig2851	newmark_ests	PMID:23079596 Forsthoefel et al., 2012
intestinal phagocyte	SMED30035214	SMESG000014644.1	Contig2851	uc_Smed_v2	PMID:23079596 Forsthoefel et al., 2012

Note: Hover over icons to view figure legend

Homology

[Close]

BLAST of ORM1-like protein vs. Ensembl Human
Match: ORMDL3 (ORMDL sphingolipid biosynthesis regulator 3 [Source:HGNC Symbol;Acc:HGNC:16038])

HSP 1 Score: 179.489 bits (454), Expect = 2.782e-56
Identity = 84/154 (54.55%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Human
Match: ORMDL2 (ORMDL sphingolipid biosynthesis regulator 2 [Source:HGNC Symbol;Acc:HGNC:16037])

HSP 1 Score: 175.637 bits (444), Expect = 9.902e-55
Identity = 82/154 (53.25%), Postives = 110/154 (71.43%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL YI+L+ ++H V L IPF S+  +WTLT   HN+  Y  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFL++ PIVL+L+ASFYTKY+  HF+IN+ +L+ + L+PKLPQ H +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHMVLLSIPFFSIPVVWTLTNVIHNLATYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSV-LLPKLPQFHGVRVFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL YI+L+ ++H V L IPF S+  +WTLT   HN+  Y  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFL++ PIVL+L+ASFYTKY+  HF+IN+ +L+ + L+PKLPQ H +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHMVLLSIPFFSIPVVWTLTNVIHNLATYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSV-LLPKLPQFHGVRVFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Fly
Match: ORMDL (gene:FBgn0037110 transcript:FBtr0078423)

HSP 1 Score: 137.502 bits (345), Expect = 2.802e-40
Identity = 69/153 (45.10%), Postives = 97/153 (63.40%), Query Frame = 1

Query:  106 QVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
             +       NP   + ++RG WL Y+L ++ VH +FL +PF+S+ W WT T   HN    + LH  KG+P+ + +   +R  T WEQ DDG Q++ T+KFLT VPIVLFL+   YT+    HFI N I+LV++ L PKLPQ H +RLFNIN++
Sbjct:    3 SIAGGHGEANPNSSWLSARGFWLAYLLGLLSVHLLFLSVPFVSIPWAWTATNLLHNAAHLYFLHVIKGAPWLSTENDPSRRWTHWEQIDDGVQMTTTRKFLTAVPIVLFLLTCLYTRNNTEHFIPNFISLVVVTL-PKLPQFHGVRLFNINKY 154

[Close]

BLAST of ORM1-like protein vs. Ensembl Zebrafish
Match: ormdl3 (ORMDL sphingolipid biosynthesis regulator 3 [Source:NCBI gene;Acc:450067])

HSP 1 Score: 179.104 bits (453), Expect = 2.016e-56
Identity = 84/154 (54.55%), Postives = 112/154 (72.73%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H + L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PI+L+ + SFYTKY+  HF+IN+I+L+ + L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLGIGLLHIILLSIPFVSVPVVWTLTNLIHNMCMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIILYFLTSFYTKYDRVHFVINTISLLTV-LIPKLPQFHGVRLFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H + L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PI+L+ + SFYTKY+  HF+IN+I+L+ + L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLGIGLLHIILLSIPFVSVPVVWTLTNLIHNMCMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIILYFLTSFYTKYDRVHFVINTISLLTV-LIPKLPQFHGVRLFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Zebrafish
Match: ormdl1 (ORMDL sphingolipid biosynthesis regulator 1 [Source:NCBI gene;Acc:368632])

HSP 1 Score: 176.407 bits (446), Expect = 2.531e-55
Identity = 83/154 (53.90%), Postives = 108/154 (70.13%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY L + M+H V L IPF SV  +WTLT   HN  MY  +H  KG+P+ET DQGKAR+LT WEQ D G Q + ++KF T+ PI+L+ +ASFYTKY+  HF+IN+ +L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLTYALGVGMLHIVLLSIPFFSVPVVWTLTNVIHNFGMYVFMHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDTAHFVINTASLLSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Zebrafish
Match: ormdl2 (ORMDL sphingolipid biosynthesis regulator 2 [Source:ZFIN;Acc:ZDB-GENE-060331-113])

HSP 1 Score: 169.859 bits (429), Expect = 1.102e-52
Identity = 86/154 (55.84%), Postives = 110/154 (71.43%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL Y+LL   +H V L IPFLSV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+++ASFYTKY+ THF++N+ +L +  L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYLLLTTALHVVLLSIPFLSVPVVWTLTNIIHNLAMYLFLHTVKGTPFETPDQGKARLLTHWEQMDYGIQFTASRKFLTISPIVLYILASFYTKYDTTHFLVNTGSL-LSVLLPKLPQFHGVRLFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL Y+LL   +H V L IPFLSV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+++ASFYTKY+ THF++N+ +L +  L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYLLLTTALHVVLLSIPFLSVPVVWTLTNIIHNLAMYLFLHTVKGTPFETPDQGKARLLTHWEQMDYGIQFTASRKFLTISPIVLYILASFYTKYDTTHFLVNTGSL-LSVLLPKLPQFHGVRLFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Xenopus
Match: birc6 (baculoviral IAP repeat containing 6 [Source:Xenbase;Acc:XB-GENE-1001894])

HSP 1 Score: 176.407 bits (446), Expect = 3.726e-55
Identity = 82/154 (53.25%), Postives = 110/154 (71.43%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL Y++L+  +H + L  PF SV  +WTLT   HN++MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+L+ASFYTKY+  HF+IN+++L +  L+PKLPQ H +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVLNSRGIWLAYVILVGFLHIILLSFPFFSVPVVWTLTNVIHNLVMYLFLHTVKGTPFETPDQGKARLLTHWEQMDYGIQFTSSRKFLTISPIVLYLLASFYTKYDPAHFLINTVSL-LSVLLPKLPQFHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Xenopus
Match: slc18b1 (solute carrier family 18, subfamily B, member 1 [Source:Xenbase;Acc:XB-GENE-953331])

HSP 1 Score: 175.637 bits (444), Expect = 6.696e-55
Identity = 85/154 (55.19%), Postives = 108/154 (70.13%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY L + M+H V L IPF SV   WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PI+L+ + SFYTKY+ THF IN+ +L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGMLHIVLLSIPFFSVPVAWTLTNVIHNLGMYVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFLTISPIILYFLTSFYTKYDPTHFFINTASLLSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Mouse
Match: Ormdl3 (ORM1-like 3 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1913862])

HSP 1 Score: 180.644 bits (457), Expect = 6.446e-57
Identity = 85/154 (55.19%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HFI+N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMTV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Mouse
Match: Ormdl1 (ORM1-like 1 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:2181669])

HSP 1 Score: 173.326 bits (438), Expect = 5.462e-54
Identity = 82/154 (53.25%), Postives = 109/154 (70.78%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY L + ++H V L IPF SV   WTLT   HN+ MY  LH  KG+P+ET DQG+AR+LT WEQ D G Q + ++KF T+ PI+L+ +ASFYTKY+ THFI+N+ +L+ + L+PK+PQLH +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFCSVPVAWTLTNIIHNLGMYVFLHAVKGTPFETPDQGRARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDPTHFILNTASLLSV-LIPKMPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Mouse
Match: Ormdl2 (ORM1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1914094])

HSP 1 Score: 167.548 bits (423), Expect = 7.513e-52
Identity = 84/154 (54.55%), Postives = 111/154 (72.08%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL YI+L+ ++H V L IPF S+  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFL++ PIVL+L+ASFYTKY+  HF+IN+ +L+ + L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHVVLLSIPFFSIPVVWTLTNVIHNLAMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSV-LLPKLPQFHGVRLFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL YI+L+ ++H V L IPF S+  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFL++ PIVL+L+ASFYTKY+  HF+IN+ +L+ + L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHVVLLSIPFFSIPVVWTLTNVIHNLAMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSV-LLPKLPQFHGVRLFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL YI+L+ ++H V L IPF S+  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFL++ PIVL+L+ASFYTKY+  HF+IN+ +L+ + L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHVVLLSIPFFSIPVVWTLTNVIHNLAMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYDAAHFLINTASLLSV-LLPKLPQFHGVRLFGINKY 153

[Close]

BLAST of ORM1-like protein vs. UniProt/SwissProt
Match: sp|Q9CPZ6|ORML3_MOUSE (ORM1-like protein 3 OS=Mus musculus OX=10090 GN=Ormdl3 PE=2 SV=1)

HSP 1 Score: 180.644 bits (457), Expect = 4.509e-56
Identity = 85/154 (55.19%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HFI+N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMTV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. UniProt/SwissProt
Match: sp|Q6QI25|ORML3_RAT (ORM1-like protein 3 OS=Rattus norvegicus OX=10116 GN=Ormdl3 PE=2 SV=2)

HSP 1 Score: 180.259 bits (456), Expect = 7.039e-56
Identity = 85/154 (55.19%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HFI+N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNLGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQVHFILNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. UniProt/SwissProt
Match: sp|Q0VD15|ORML3_BOVIN (ORM1-like protein 3 OS=Bos taurus OX=9913 GN=ORMDL3 PE=2 SV=1)

HSP 1 Score: 179.874 bits (455), Expect = 1.007e-55
Identity = 85/154 (55.19%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HFI+N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFILNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. UniProt/SwissProt
Match: sp|Q5R570|ORML3_PONAB (ORM1-like protein 3 OS=Pongo abelii OX=9601 GN=ORMDL3 PE=2 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 1.293e-55
Identity = 84/154 (54.55%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHVVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. UniProt/SwissProt
Match: sp|Q8N138|ORML3_HUMAN (ORM1-like protein 3 OS=Homo sapiens OX=9606 GN=ORMDL3 PE=1 SV=1)

HSP 1 Score: 179.489 bits (454), Expect = 1.336e-55
Identity = 84/154 (54.55%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y+L I ++H V L IPF+SV  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGMYIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYDQIHFVLNTVSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. TrEMBL
Match: A0A4E0RW75 (Oligosaccharyltransferase complex subunit delta OS=Fasciola hepatica OX=6192 GN=D915_007103 PE=4 SV=1)

HSP 1 Score: 246.128 bits (627), Expect = 2.735e-79
Identity = 113/153 (73.86%), Postives = 134/153 (87.58%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINR 561
            MQVGTA S  NPT  YFNS+G+W+TYIL+I++VHFV LC+PFLS A +WTLTC+ HNV MY  LHWEKGSPYETLDQG+ARVLTQWEQFDDGEQ SPTKKFL VVPIVLFL+ASFYT+Y+ TH +IN+ +L+ILA++PKLPQ +R+RLF INR
Sbjct:    1 MQVGTATSVLNPTSEYFNSQGTWVTYILVIVIVHFVLLCVPFLSTAVVWTLTCSIHNVFMYLFLHWEKGSPYETLDQGEARVLTQWEQFDDGEQFSPTKKFLLVVPIVLFLLASFYTEYDPTHCLINASSLIILAVLPKLPQFYRVRLFGINR 153

[Close]

BLAST of ORM1-like protein vs. TrEMBL
Match: A0A0X3PJJ1 (ORM1-like protein 2 OS=Schistocephalus solidus OX=70667 GN=ORML2 PE=4 SV=1)

HSP 1 Score: 243.817 bits (621), Expect = 1.870e-78
Identity = 110/153 (71.90%), Postives = 133/153 (86.93%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINR 561
            MQVGTA ST NPTF Y NS G+W+TY++LI + HF FLCIPFLSVA +WTLTCTFHNV+ Y +LHWEKGSPYETLDQG+ARVLTQWEQFDDGEQ SPTKKFL VVPIV+F++ASFYT+Y+  HF IN+  L++L+++PKLPQ +R+R+F INR
Sbjct:    1 MQVGTATSTANPTFDYLNSTGTWITYLILIALCHFFFLCIPFLSVASVWTLTCTFHNVITYLLLHWEKGSPYETLDQGEARVLTQWEQFDDGEQYSPTKKFLLVVPIVIFILASFYTQYDPIHFAINASTLILLSILPKLPQFYRVRVFGINR 153

[Close]

BLAST of ORM1-like protein vs. TrEMBL
Match: A0A564Y020 (Uncharacterized protein OS=Hymenolepis diminuta OX=6216 GN=WMSIL1_LOCUS1097 PE=4 SV=1)

HSP 1 Score: 239.58 bits (610), Expect = 8.270e-77
Identity = 108/154 (70.13%), Postives = 131/154 (85.06%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            MQVGTA ST NPT  Y NS G+W+TY+LLI   H + LCIPFLSVA +WTLTCT HNVL Y ILHWEKGSPYETLDQG+ARVLTQWEQFDDGEQ SPTKKFL VVPI++F++ASFYT+Y+  HF+IN+  L++L+++PKLPQ +R+R+F INR+
Sbjct:    1 MQVGTATSTANPTSEYLNSTGTWITYLLLIAGCHLILLCIPFLSVASVWTLTCTLHNVLTYLILHWEKGSPYETLDQGEARVLTQWEQFDDGEQYSPTKKFLLVVPIIIFILASFYTQYDPIHFVINASTLILLSILPKLPQFYRVRVFGINRW 154

[Close]

BLAST of ORM1-like protein vs. TrEMBL
Match: A0A0R3TVL9 (Uncharacterized protein OS=Rodentolepis nana OX=102285 GN=HNAJ_LOCUS11862 PE=4 SV=1)

HSP 1 Score: 238.81 bits (608), Expect = 1.663e-76
Identity = 108/154 (70.13%), Postives = 131/154 (85.06%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            MQVGTA ST NPT  Y NS G+W+TY+LLI   H + LCIPFLSVA +WTLTCT HNVL Y ILHWEKGSPYETLDQG+ARVLTQWEQFDDGEQ SPTKKFL VVPI++F++ASFYT+Y+  HF+IN+  L++L+++PKLPQ +R+R+F INR+
Sbjct:    1 MQVGTATSTANPTSEYINSTGTWITYLLLIAGFHLILLCIPFLSVASVWTLTCTLHNVLTYLILHWEKGSPYETLDQGEARVLTQWEQFDDGEQYSPTKKFLLVVPIIIFILASFYTQYDPIHFVINASTLILLSILPKLPQFYRVRVFGINRW 154

[Close]

BLAST of ORM1-like protein vs. TrEMBL
Match: A0A4S2LE16 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_009592 PE=4 SV=1)

HSP 1 Score: 238.81 bits (608), Expect = 1.719e-76
Identity = 107/153 (69.93%), Postives = 132/153 (86.27%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINR 561
            MQVGTA S  NPT  YFNS G+W+TYIL+I++ HFV LC+PFL+ A +WTLTC+ HN +MY +LHWEKGSPYETLDQG+ARVLTQWEQFDDGEQ SPTKKFL VVPIVLFL+ASFYT+Y+  H +IN+ +L++LA++PKLPQ +R+R+F INR
Sbjct:    1 MQVGTATSVLNPTSEYFNSHGTWVTYILIIVLGHFVLLCVPFLTTAVVWTLTCSIHNAVMYLLLHWEKGSPYETLDQGEARVLTQWEQFDDGEQFSPTKKFLLVVPIVLFLLASFYTEYDPMHCLINASSLIVLAVLPKLPQFYRVRIFGINR 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Cavefish
Match: ormdl2 (ORM1-like protein 2 [Source:NCBI gene;Acc:103029753])

HSP 1 Score: 184.882 bits (468), Expect = 9.911e-59
Identity = 89/154 (57.79%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY+LL I++H V L IPF SV+ +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+L+ASFYTKY+ THF+IN+ +L +  L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLTYLLLTIVLHVVLLSIPFFSVSLVWTLTNVIHNLAMYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGIQFTSSRKFLTISPIVLYLLASFYTKYDATHFLINTGSL-LSVLLPKLPQFHGVRLFGINKY 153

[Close]

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY+LL I++H V L IPF SV+ +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D G Q + ++KFLT+ PIVL+L+ASFYTKY+ THF+IN+ +L +  L+PKLPQ H +RLF IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLTYLLLTIVLHVVLLSIPFFSVSLVWTLTNVIHNLAMYVFLHTVKGTPFETPDQGKARLLTHWEQMDYGIQFTSSRKFLTISPIVLYLLASFYTKYDATHFLINTGSL-LSVLLPKLPQFHGVRLFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Cavefish
Match: ormdl1 (ORMDL sphingolipid biosynthesis regulator 1 [Source:NCBI gene;Acc:103027115])

HSP 1 Score: 174.481 bits (441), Expect = 1.465e-54
Identity = 82/154 (53.25%), Postives = 107/154 (69.48%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY L + M+H V L IPF SV  +WTLT   HN  MY  +H  KG+P+ET DQGKAR+LT WEQ D G Q + ++KF T+ PI+L+ +ASFYTKY+  HF+IN+ +L+ + L+PKLPQLH +R+  IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLTYALGVGMLHIVLLSIPFFSVPVVWTLTNVIHNFGMYVFMHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDTAHFVINTASLLSV-LIPKLPQLHGVRILGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Cavefish
Match: ormdl1 (ORMDL sphingolipid biosynthesis regulator 1 [Source:NCBI gene;Acc:103027115])

HSP 1 Score: 173.711 bits (439), Expect = 1.065e-53
Identity = 82/156 (52.56%), Postives = 108/156 (69.23%), Query Frame = 1

Query:   97 LNMQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            + M VG A S  NP     NSRG WLTY L + M+H V L IPF SV  +WTLT   HN  MY  +H  KG+P+ET DQGKAR+LT WEQ D G Q + ++KF T+ PI+L+ +ASFYTKY+  HF+IN+ +L+ + L+PKLPQLH +R+  IN++
Sbjct:   44 VKMNVGVAHSEVNPNTRVMNSRGIWLTYALGVGMLHIVLLSIPFFSVPVVWTLTNVIHNFGMYVFMHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDTAHFVINTASLLSV-LIPKLPQLHGVRILGINKY 198

[Close]

BLAST of ORM1-like protein vs. Ensembl Sea Lamprey
Match: ormdl3 (ORMDL sphingolipid biosynthesis regulator 3 [Source:NCBI gene;Acc:450067])

HSP 1 Score: 181.03 bits (458), Expect = 6.163e-58
Identity = 84/154 (54.55%), Postives = 113/154 (73.38%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M+VGTA S  NP     NSRG WLTY+L I ++H V L IPF SV+ +WTLT   HN+ MY  LH  KG+P+ET DQGK R+LT WEQ D G Q + ++KFLT+ PIVL+ + SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MEVGTAHSEVNPNTRVMNSRGIWLTYVLAIGLLHVVLLSIPFCSVSLVWTLTNVIHNLGMYIFLHTVKGTPFETPDQGKDRLLTHWEQMDYGVQFTSSRKFLTITPIVLYFLTSFYTKYDAVHFVVNTLSLMSV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Sea Lamprey
Match: ormdl2 (ORMDL sphingolipid biosynthesis regulator 2 [Source:ZFIN;Acc:ZDB-GENE-060331-113])

HSP 1 Score: 167.933 bits (424), Expect = 1.039e-52
Identity = 84/154 (54.55%), Postives = 112/154 (72.73%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WL+Y+L ++++H V L IPF+SV  +WTLT   HNV MY  LH  KG+P+ET DQG+AR+LT WEQ D G Q + ++KFLT+ PIVL+ +ASFYTKYEV HF++N+++L +  L+PKLPQLH +R   IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGMWLSYVLAVLLLHVVLLSIPFVSVPVVWTLTNVIHNVGMYLFLHTLKGTPFETPDQGRARLLTYWEQMDHGFQYTASRKFLTISPIVLYFLASFYTKYEVAHFVVNTVSL-LSVLIPKLPQLHGVRFLGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Yeast
Match: ORM2 (Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; protein abundance increases in response to DNA replication stress; ORM2 has a paralog, ORM1, that arose from the whole genome duplication [Source:SGD;Acc:S000004342])

HSP 1 Score: 94.3597 bits (233), Expect = 6.855e-24
Identity = 51/139 (36.69%), Postives = 85/139 (61.15%), Query Frame = 1

Query:  130 PNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRL 546
            PN    + + RG+WL +I++I+++  +F  +   +  W WTLT   + +  Y + H  KG+P++  + G    LT WEQ +D    +PT+KFL +VPIVLFLI++ Y + ++T F+ N    V++ +VPKL   HR+R+
Sbjct:   68 PNMNATWVDQRGAWLIHIVVIVLLR-LFYSLFGSTPKWTWTLTNMTYIIGFYIMFHLVKGTPFD-FNGGAYDNLTMWEQINDETLYTPTRKFLLIVPIVLFLISNQYYRNDMTLFLSNLAVTVLIGVVPKLGITHRLRI 204

[Close]

BLAST of ORM1-like protein vs. Ensembl Yeast
Match: ORM1 (Protein that mediates sphingolipid homeostasis; evolutionarily conserved, required for resistance to agents that induce unfolded protein response; Orm1p and Orm2p together control membrane biogenesis by coordinating lipid homeostasis with protein quality control; ORM1 has a paralog, ORM2, that arose from the whole genome duplication [Source:SGD;Acc:S000003270])

HSP 1 Score: 89.7373 bits (221), Expect = 5.249e-22
Identity = 49/139 (35.25%), Postives = 80/139 (57.55%), Query Frame = 1

Query:  130 PNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRL 546
            PN    + + RG+W+ ++++II++   +   P ++  W WTLT   + +  Y + H  KG+P++  + G    LT WEQ DD    +P++KFL  VPI LFL+++ Y  Y++  F  N       A+VPKLP  HR+R+
Sbjct:   73 PNMNATWVDQRGAWIIHVVIIILLKLFYNLFPGVTTEWSWTLTNMTYVIGSYVMFHLIKGTPFD-FNGGAYDNLTMWEQIDDETLYTPSRKFLISVPIALFLVSTHYAHYDLKLFSWNCFLTTFGAVVPKLPVTHRLRI 210

[Close]

BLAST of ORM1-like protein vs. Ensembl Nematostella
Match: EDO43655 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RY87])

HSP 1 Score: 178.333 bits (451), Expect = 1.768e-56
Identity = 83/154 (53.90%), Postives = 119/154 (77.27%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            MQVGTA S  NP   + +S+G+WLTYI++II+ H V L +PF + +  WTLT T HN+ M+ +LH+ KG+P+ET DQGKAR LT WEQ + G Q + T+KF T++PI LF+I SFYTKY+  HFIIN+++L++L+LVPK PQ++++RLF +N++
Sbjct:    1 MQVGTAHSIDNPNESWLDSKGTWLTYIIMIILGHLVILSVPFFATSTAWTLTNTMHNLCMFLLLHYVKGTPFETSDQGKARRLTHWEQINQGVQFTQTRKFFTLIPIFLFMITSFYTKYDGIHFIINAVSLLLLSLVPKFPQMYKVRLFGLNKY 154

[Close]

BLAST of ORM1-like protein vs. Ensembl Nematostella
Match: EDO28402 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6K3])

HSP 1 Score: 67.0106 bits (162), Expect = 8.034e-15
Identity = 28/50 (56.00%), Postives = 38/50 (76.00%), Query Frame = 1

Query:  280 MYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVL 429
            M+ +LH+ KG+P+ET DQGKAR LT WEQ + G Q + T+KF T++PI L
Sbjct:    5 MFLLLHYVKGTPFETSDQGKARRLTHWEQINQGVQFTQTRKFFTLIPIFL 54

[Close]

BLAST of ORM1-like protein vs. Ensembl Medaka
Match: ormdl3 (ORM1-like protein 3 [Source:NCBI gene;Acc:111946406])

HSP 1 Score: 182.185 bits (461), Expect = 1.252e-57
Identity = 84/154 (54.55%), Postives = 114/154 (74.03%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VGTA S  NP     NSRG WL+Y L I ++H + L IPF+SV  +WTLT   HN+ MY +LH  KG+P++T DQGKAR+LT WEQ D G Q + ++KFLTV PIVL+L+ SFYTKY+  HF++N+++L+ + L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGTAHSEVNPNTRVMNSRGMWLSYTLSIGLLHLILLSIPFVSVPVVWTLTNMIHNLCMYLLLHTVKGTPFQTPDQGKARLLTHWEQMDYGVQFTASRKFLTVTPIVLYLLTSFYTKYDRVHFVVNTVSLLTV-LIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Medaka
Match: ormdl1 (ORMDL sphingolipid biosynthesis regulator 1 [Source:NCBI gene;Acc:101160518])

HSP 1 Score: 176.022 bits (445), Expect = 3.291e-55
Identity = 83/154 (53.90%), Postives = 108/154 (70.13%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY L + ++H V L IPF SV  +WTLT   HN  MY  +H  KG+P+ET DQGKAR+LT WEQ D G Q + ++KF T+ PI+L+ +ASFYTKY+ THF+IN+ +L +  L+PKLPQLH +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLTYALGVGVLHIVLLSIPFFSVPVVWTLTNVIHNFGMYVFMHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDTTHFVINTASL-LSVLIPKLPQLHGVRIFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Ensembl Medaka
Match: ENSORLT00000019052.2 (ORM1-like protein 2 [Source:NCBI gene;Acc:101173704])

HSP 1 Score: 159.458 bits (402), Expect = 1.012e-48
Identity = 85/154 (55.19%), Postives = 112/154 (72.73%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            M VG A S  NP     NSRG WLTY+LL +++H V L IPFL+V  +WTLT   HN+ MY  LH  KG+P+ET DQGKAR+LT WEQ D+G Q + ++KFLT+ PIVL+++ SFYTKY+ THF IN+ +L +  L+PKLPQ H +R+F IN++
Sbjct:    1 MNVGVAHSEVNPNTRVMNSRGIWLTYLLLTVVLHVVLLSIPFLTVPLVWTLTNVIHNLAMYLFLHTVKGTPFETPDQGKARLLTHWEQMDNGIQFTSSRKFLTISPIVLYILTSFYTKYDPTHFFINTCSL-LSVLLPKLPQFHGVRVFGINKY 153

[Close]

BLAST of ORM1-like protein vs. Planmine SMEST
Match: SMESG000024189.1 (SMESG000024189.1)

HSP 1 Score: 317.005 bits (811), Expect = 6.666e-111
Identity = 154/154 (100.00%), Postives = 154/154 (100.00%), Query Frame = 1

Query:  103 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 564
            MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF
Sbjct:    1 MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWTLTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKKFLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFNINRF 154

The following BLAST results are available for this feature:

BLAST of ORM1-like protein vs. Ensembl Human
BLAST of ORM1-like protein vs. Ensembl Celegans
BLAST of ORM1-like protein vs. Ensembl Fly
BLAST of ORM1-like protein vs. Ensembl Zebrafish
BLAST of ORM1-like protein vs. Ensembl Xenopus
BLAST of ORM1-like protein vs. Ensembl Mouse
BLAST of ORM1-like protein vs. UniProt/SwissProt
BLAST of ORM1-like protein vs. TrEMBL
BLAST of ORM1-like protein vs. Ensembl Cavefish
BLAST of ORM1-like protein vs. Ensembl Sea Lamprey
BLAST of ORM1-like protein vs. Ensembl Yeast
BLAST of ORM1-like protein vs. Ensembl Nematostella
BLAST of ORM1-like protein vs. Ensembl Medaka
BLAST of ORM1-like protein vs. Planmine SMEST

BLAST of ORM1-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ORMDL3	2.782e-56	54.55	ORMDL sphingolipid biosynthesis regulator 3 [Sourc...	[more]
ORMDL3	2.782e-56	54.55	ORMDL sphingolipid biosynthesis regulator 3 [Sourc...	[more]
ORMDL3	2.782e-56	54.55	ORMDL sphingolipid biosynthesis regulator 3 [Sourc...	[more]
ORMDL2	9.902e-55	53.25	ORMDL sphingolipid biosynthesis regulator 2 [Sourc...	[more]
ORMDL2	9.902e-55	53.25	ORMDL sphingolipid biosynthesis regulator 2 [Sourc...	[more]

BLAST of ORM1-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of ORM1-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ORMDL	2.802e-40	45.10	gene:FBgn0037110 transcript:FBtr0078423	[more]

BLAST of ORM1-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
ormdl3	2.016e-56	54.55	ORMDL sphingolipid biosynthesis regulator 3 [Sourc...	[more]
ormdl3	2.016e-56	54.55	ORMDL sphingolipid biosynthesis regulator 3 [Sourc...	[more]
ormdl1	2.531e-55	53.90	ORMDL sphingolipid biosynthesis regulator 1 [Sourc...	[more]
ormdl2	1.102e-52	55.84	ORMDL sphingolipid biosynthesis regulator 2 [Sourc...	[more]
ormdl2	1.102e-52	55.84	ORMDL sphingolipid biosynthesis regulator 2 [Sourc...	[more]

BLAST of ORM1-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 2


Match Name	E-value	Identity	Description
birc6	3.726e-55	53.25	baculoviral IAP repeat containing 6 [Source:Xenbas...	[more]
slc18b1	6.696e-55	55.19	solute carrier family 18, subfamily B, member 1 [S...	[more]

BLAST of ORM1-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ormdl3	6.446e-57	55.19	ORM1-like 3 (S. cerevisiae) [Source:MGI Symbol;Acc...	[more]
Ormdl1	5.462e-54	53.25	ORM1-like 1 (S. cerevisiae) [Source:MGI Symbol;Acc...	[more]
Ormdl2	7.513e-52	54.55	ORM1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc...	[more]
Ormdl2	7.513e-52	54.55	ORM1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc...	[more]
Ormdl2	7.513e-52	54.55	ORM1-like 2 (S. cerevisiae) [Source:MGI Symbol;Acc...	[more]

BLAST of ORM1-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|Q9CPZ6\|ORML3_MOUSE	4.509e-56	55.19	ORM1-like protein 3 OS=Mus musculus OX=10090 GN=Or...	[more]
sp\|Q6QI25\|ORML3_RAT	7.039e-56	55.19	ORM1-like protein 3 OS=Rattus norvegicus OX=10116 ...	[more]
sp\|Q0VD15\|ORML3_BOVIN	1.007e-55	55.19	ORM1-like protein 3 OS=Bos taurus OX=9913 GN=ORMDL...	[more]
sp\|Q5R570\|ORML3_PONAB	1.293e-55	54.55	ORM1-like protein 3 OS=Pongo abelii OX=9601 GN=ORM...	[more]
sp\|Q8N138\|ORML3_HUMAN	1.336e-55	54.55	ORM1-like protein 3 OS=Homo sapiens OX=9606 GN=ORM...	[more]

BLAST of ORM1-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A4E0RW75	2.735e-79	73.86	Oligosaccharyltransferase complex subunit delta OS...	[more]
A0A0X3PJJ1	1.870e-78	71.90	ORM1-like protein 2 OS=Schistocephalus solidus OX=...	[more]
A0A564Y020	8.270e-77	70.13	Uncharacterized protein OS=Hymenolepis diminuta OX...	[more]
A0A0R3TVL9	1.663e-76	70.13	Uncharacterized protein OS=Rodentolepis nana OX=10...	[more]
A0A4S2LE16	1.719e-76	69.93	Uncharacterized protein OS=Opisthorchis felineus O...	[more]

BLAST of ORM1-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
ormdl2	9.911e-59	57.79	ORM1-like protein 2 [Source:NCBI gene;Acc:10302975...	[more]
ormdl2	9.911e-59	57.79	ORM1-like protein 2 [Source:NCBI gene;Acc:10302975...	[more]
ormdl1	1.465e-54	53.25	ORMDL sphingolipid biosynthesis regulator 1 [Sourc...	[more]
ormdl1	1.065e-53	52.56	ORMDL sphingolipid biosynthesis regulator 1 [Sourc...	[more]

BLAST of ORM1-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2


Match Name	E-value	Identity	Description
ormdl3	6.163e-58	54.55	ORMDL sphingolipid biosynthesis regulator 3 [Sourc...	[more]
ormdl2	1.039e-52	54.55	ORMDL sphingolipid biosynthesis regulator 2 [Sourc...	[more]

BLAST of ORM1-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2


Match Name	E-value	Identity	Description
ORM2	6.855e-24	36.69	Protein that mediates sphingolipid homeostasis; ev...	[more]
ORM1	5.249e-22	35.25	Protein that mediates sphingolipid homeostasis; ev...	[more]

BLAST of ORM1-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
EDO43655	1.768e-56	53.90	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]
EDO28402	8.034e-15	56.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of ORM1-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
ormdl3	1.252e-57	54.55	ORM1-like protein 3 [Source:NCBI gene;Acc:11194640...	[more]
ormdl1	3.291e-55	53.90	ORMDL sphingolipid biosynthesis regulator 1 [Sourc...	[more]
ENSORLT00000019052.2	1.012e-48	55.19	ORM1-like protein 2 [Source:NCBI gene;Acc:10117370...	[more]

BLAST of ORM1-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000024189.1	6.666e-111	100.00	SMESG000024189.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30035214 ID=SMED30035214|Name=ORM1-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=831bp
GCCACTTTATGCGGTAAATTGAAAATATAAATAAAAAGTCGTAATTATTG
TTAATTTTGATTTCAAATTACACACTGTTTAAGAATTCAGTAAATATTGA
ATATGCAAGTTGGTACAGCTGATTCGACTCCAAATCCGACATTTCATTAT
TTTAATAGTCGTGGTTCATGGCTAACATACATCTTACTTATTATTATGGT
TCATTTTGTTTTTCTCTGTATACCTTTCCTATCTGTAGCATGGATATGGA
CACTAACTTGCACATTTCATAATGTTTTGATGTATTTTATACTTCATTGG
GAAAAGGGAAGTCCCTACGAAACTCTTGATCAAGGTAAAGCAAGAGTTTT
AACTCAATGGGAACAGTTCGATGATGGTGAGCAGTTATCTCCAACAAAAA
AATTTCTCACTGTGGTTCCAATAGTATTATTTTTGATTGCCAGTTTCTAT
ACAAAATATGAAGTCACTCATTTCATTATCAATTCAATCGCATTAGTTAT
TTTAGCATTGGTTCCAAAGCTTCCACAGTTGCATCGTATCCGGTTATTTA
ATATCAATCGATTTTAATCTGATTTGGATGATTGATTATTATTATTATTA
TTATGTCATCCATACAATATATAAAATATTCTCTGTGAATAAGATTTTAA
AAATGGAATAAACATTTAGTGAACTTTCTGATTTTCAATTACATAATATC
TTTGAAGATTATTCTATTGATTGTTTTTTGAAAGCAATACTTTTGTAAAA
TGATTGGATCAAGTATTGTTTTTATTTTCAATTTGATTTTAGATGATTAT
TATTATTATTATGTAACATATTAATTTTGGC

protein sequence of SMED30035214-orf-1

>SMED30035214-orf-1 ID=SMED30035214-orf-1|Name=SMED30035214-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=155bp
MQVGTADSTPNPTFHYFNSRGSWLTYILLIIMVHFVFLCIPFLSVAWIWT
LTCTFHNVLMYFILHWEKGSPYETLDQGKARVLTQWEQFDDGEQLSPTKK
FLTVVPIVLFLIASFYTKYEVTHFIINSIALVILALVPKLPQLHRIRLFN
INRF*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0006672	ceramide metabolic process
GO:0090155	negative regulation of sphingolipid biosynthetic process
GO:0090156	cellular sphingolipid homeostasis

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000070	intestinal phagocyte
PLANA:0002056	medial muscle cell

Vocabulary: **INTERPRO**
Term	Definition
IPR029883	ORML3
IPR007203	ORMDL

Vocabulary: **cellular component**
Term	Definition
GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane
GO:0016020	membrane

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR007203	ORMDL family	PFAM	PF04061	ORMDL	coord: 11..147 e-value: 5.9E-51 score: 171.8
IPR007203	ORMDL family	PIRSF	PIRSF018147	ORM1	coord: 1..154 e-value: 2.0E-57 score: 191.6
IPR007203	ORMDL family	PANTHER	PTHR12665	ORMDL PROTEINS	coord: 1..154
IPR029883	ORM1-like protein 3	PANTHER	PTHR12665:SF11	ORM1-LIKE PROTEIN 3	coord: 1..154
None	No IPR available	TMHMM	TMhelix		coord: 23..45
None	No IPR available	TMHMM	TMhelix		coord: 101..117
None	No IPR available	TMHMM	TMhelix		coord: 121..143

Main menu

ORM1-like protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 4

Owlery

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