Heat shock protein 90

Overview
NameHeat shock protein 90
Smed IDSMED30035193
Length (bp)2392
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Heat shock protein 90 (SMED30035193) t-SNE clustered cells

Violin plots show distribution of expression levels for Heat shock protein 90 (SMED30035193) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Heat shock protein 90 (SMED30035193) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Heat shock protein 90 (SMED30035193) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30035193

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 23

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
intestinal phagocyteSMED30035193SMESG000057910.1 Contig4101GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035193SMESG000071533.1 SMESG000071531.1 Contig1817GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
intestinal phagocyteSMED30035193SMESG000071533.1 SMESG000071531.1 Contig4101GPL15192PMID:23079596
Forsthoefel et al., 2012
FACS sorted cell population asexual adult cDNA to DNA expression microarray evidence
Smed sexual biotypeSMED30035193SMESG000071533.1 SMESG000071531.1 Contig37821newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035193SMESG000071533.1 SMESG000071531.1 Contig37821uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035193SMESG000057910.1 Contig4101GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035193SMESG000071533.1 SMESG000071531.1 Contig9359newmark_estsPMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035193SMESG000071533.1 SMESG000071531.1 Contig9359uc_Smed_v2PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035193SMESG000071533.1 SMESG000071531.1 Contig4101GPL15192PMID:29674431
Fincher et al., 2018
FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
pharynxSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymaSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cilated neuronSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30035193 dd_Smed_v4_56_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035193SMESG000071533.1 SMESG000071531.1 dd_Smed_v6_56_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Category 3 cellSMED30035193SMESG000071533.1 SMESG000071531.1 dd_Smed_v6_56_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
neoblastSMED30035193SMESG000071533.1 SMESG000071531.1 dd_Smed_v6_56_0dd_Smed_v6PMID:29674432
Plass et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 346/445 (77.75%), Postives = 399/445 (89.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD   D T A    ++P  P   +D+  +MEEVD
Sbjct:  290 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 732          

HSP 2 Score: 356.681 bits (914), Expect = 4.516e-111
Identity = 180/220 (81.82%), Postives = 201/220 (91.36%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231          
BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AA1 (heat shock protein 90 alpha family class A member 1 [Source:HGNC Symbol;Acc:HGNC:5253])

HSP 1 Score: 689.493 bits (1778), Expect = 0.000e+0
Identity = 346/445 (77.75%), Postives = 399/445 (89.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD   D T A    ++P  P   +D+  +MEEVD
Sbjct:  412 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 854          

HSP 2 Score: 355.525 bits (911), Expect = 2.364e-109
Identity = 180/220 (81.82%), Postives = 201/220 (91.36%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:  134 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 353          
BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 342/445 (76.85%), Postives = 400/445 (89.89%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KN+KLGIHEDS NR +++E LR++++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ V +SAFVER+ KRGFEV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++D+V   E +A    +IP  P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIP--PLEGDEDASRMEEVD 724          

HSP 2 Score: 348.591 bits (893), Expect = 3.935e-108
Identity = 175/213 (82.16%), Postives = 197/213 (92.49%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L I IIP+    TLT+VDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D+ EPIGRG+KVIL++KEDQ EYL+E+++KE++KKHSQFIGYPI L LEKER+KEIS
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226          
BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 342/445 (76.85%), Postives = 400/445 (89.89%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KN+KLGIHEDS NR +++E LR++++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ V +SAFVER+ KRGFEV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++D+V   E +A    +IP  P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIP--PLEGDEDASRMEEVD 724          

HSP 2 Score: 348.591 bits (893), Expect = 3.935e-108
Identity = 175/213 (82.16%), Postives = 197/213 (92.49%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L I IIP+    TLT+VDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D+ EPIGRG+KVIL++KEDQ EYL+E+++KE++KKHSQFIGYPI L LEKER+KEIS
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226          
BLAST of Heat shock protein 90 vs. Ensembl Human
Match: HSP90AB1 (heat shock protein 90 alpha family class B member 1 [Source:HGNC Symbol;Acc:HGNC:5258])

HSP 1 Score: 662.914 bits (1709), Expect = 0.000e+0
Identity = 342/445 (76.85%), Postives = 400/445 (89.89%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KN+KLGIHEDS NR +++E LR++++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ V +SAFVER+ KRGFEV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++D+V   E +A    +IP  P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVAAEEPNAAVPDEIP--PLEGDEDASRMEEVD 724          

HSP 2 Score: 348.591 bits (893), Expect = 3.935e-108
Identity = 175/213 (82.16%), Postives = 197/213 (92.49%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L I IIP+    TLT+VDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D+ EPIGRG+KVIL++KEDQ EYL+E+++KE++KKHSQFIGYPI L LEKER+KEIS
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226          
BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: hsp-90 (Heat shock protein 90 [Source:UniProtKB/Swiss-Prot;Acc:Q18688])

HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0
Identity = 350/448 (78.12%), Postives = 398/448 (88.84%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTS------TEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KN+KLGIHEDS NR K+++FLR YSTS+G+E TSLK+Y+SRMKENQ  IYYITGESKD V  SAFVER+  RGFEVL M DPIDEY VQQLKEYDGKKLV VTKEGLELPE E+EKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH+IMK+L+ RV+ DKNDK+VKDLV+LLFET+LL+SGFSLE+PQ H +RI+RMIKLGL I DD++E  A     +P   T+       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLR-YSTSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDIGDDEIEDSA-----VPSSCTAEAKIEGAEEDASRMEEVD 702          

HSP 2 Score: 315.849 bits (808), Expect = 2.191e-96
Identity = 160/209 (76.56%), Postives = 191/209 (91.39%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            MSE +AETFAFQAEIAQLMSLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LD+ K+L IKI P+K+  TLTI+DTGIGMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK+NDD+ Y WESSAGGSF ++  N   + RG+K+++++KEDQI++L+E+KIKEI+KKHSQFIGYPIKL
Sbjct:    1 MSE-NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208          
BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: hsp-90 (Heat shock protein 90 [Source:UniProtKB/Swiss-Prot;Acc:Q18688])

HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0
Identity = 350/448 (78.12%), Postives = 398/448 (88.84%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTS------TEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KN+KLGIHEDS NR K+++FLR YSTS+G+E TSLK+Y+SRMKENQ  IYYITGESKD V  SAFVER+  RGFEVL M DPIDEY VQQLKEYDGKKLV VTKEGLELPE E+EKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH+IMK+L+ RV+ DKNDK+VKDLV+LLFET+LL+SGFSLE+PQ H +RI+RMIKLGL I DD++E  A     +P   T+       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLR-YSTSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDIGDDEIEDSA-----VPSSCTAEAKIEGAEEDASRMEEVD 702          

HSP 2 Score: 315.849 bits (808), Expect = 2.191e-96
Identity = 160/209 (76.56%), Postives = 191/209 (91.39%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            MSE +AETFAFQAEIAQLMSLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LD+ K+L IKI P+K+  TLTI+DTGIGMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK+NDD+ Y WESSAGGSF ++  N   + RG+K+++++KEDQI++L+E+KIKEI+KKHSQFIGYPIKL
Sbjct:    1 MSE-NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208          
BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: hsp-90 (Heat shock protein 90 [Source:UniProtKB/Swiss-Prot;Acc:Q18688])

HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0
Identity = 350/448 (78.12%), Postives = 398/448 (88.84%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTS------TEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KN+KLGIHEDS NR K+++FLR YSTS+G+E TSLK+Y+SRMKENQ  IYYITGESKD V  SAFVER+  RGFEVL M DPIDEY VQQLKEYDGKKLV VTKEGLELPE E+EKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH+IMK+L+ RV+ DKNDK+VKDLV+LLFET+LL+SGFSLE+PQ H +RI+RMIKLGL I DD++E  A     +P   T+       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLR-YSTSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDIGDDEIEDSA-----VPSSCTAEAKIEGAEEDASRMEEVD 702          

HSP 2 Score: 315.849 bits (808), Expect = 2.191e-96
Identity = 160/209 (76.56%), Postives = 191/209 (91.39%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            MSE +AETFAFQAEIAQLMSLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LD+ K+L IKI P+K+  TLTI+DTGIGMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK+NDD+ Y WESSAGGSF ++  N   + RG+K+++++KEDQI++L+E+KIKEI+KKHSQFIGYPIKL
Sbjct:    1 MSE-NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208          
BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: hsp-90 (Heat shock protein 90 [Source:UniProtKB/Swiss-Prot;Acc:Q18688])

HSP 1 Score: 681.404 bits (1757), Expect = 0.000e+0
Identity = 350/448 (78.12%), Postives = 398/448 (88.84%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTS------TEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N+IKLYVRRVFIM+NCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+EL +E+ EDKDN+KKFYEQF KN+KLGIHEDS NR K+++FLR YSTS+G+E TSLK+Y+SRMKENQ  IYYITGESKD V  SAFVER+  RGFEVL M DPIDEY VQQLKEYDGKKLV VTKEGLELPE E+EKKKFEE K A+E LCKV+KDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDH+IMK+L+ RV+ DKNDK+VKDLV+LLFET+LL+SGFSLE+PQ H +RI+RMIKLGL I DD++E  A     +P   T+       E++A +MEEVD
Sbjct:  261 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKSKNSIKLYVRRVFIMENCEELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCMELIDEVAEDKDNFKKFYEQFGKNLKLGIHEDSTNRKKLSDFLR-YSTSAGDEPTSLKEYVSRMKENQTQIYYITGESKDVVAASAFVERVKSRGFEVLYMCDPIDEYCVQQLKEYDGKKLVSVTKEGLELPETEEEKKKFEEDKVAYENLCKVIKDILEKKVEKVGVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHAIMKTLRDRVEVDKNDKTVKDLVVLLFETALLASGFSLEEPQSHASRIYRMIKLGLDIGDDEIEDSA-----VPSSCTAEAKIEGAEEDASRMEEVD 702          

HSP 2 Score: 315.849 bits (808), Expect = 2.191e-96
Identity = 160/209 (76.56%), Postives = 191/209 (91.39%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            MSE +AETFAFQAEIAQLMSLIINTFYSNKEI+LRELISN+SDALDKIRY++LT+PS LD+ K+L IKI P+K+  TLTI+DTGIGMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK+NDD+ Y WESSAGGSF ++  N   + RG+K+++++KEDQI++L+E+KIKEI+KKHSQFIGYPIKL
Sbjct:    1 MSE-NAETFAFQAEIAQLMSLIINTFYSNKEIYLRELISNASDALDKIRYQALTEPSELDTGKELFIKITPNKEEKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVTSKNNDDDSYQWESSAGGSFVVRPFNDPEVTRGTKIVMHIKEDQIDFLEERKIKEIVKKHSQFIGYPIKL 208          
BLAST of Heat shock protein 90 vs. Ensembl Celegans
Match: enpl-1 (Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q22235])

HSP 1 Score: 338.961 bits (868), Expect = 3.091e-105
Identity = 188/417 (45.08%), Postives = 275/417 (65.95%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKR-NNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDI-LDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDD 2245
            +N  KPIW R P+ V +++Y +FYKS+T D E+ L+  HFS EG++ FR++L+ PK++P D+F+N  K   NIKLYVRRVFI D+  D++P+YL+F++G+VDS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++ +++  D   +  F+ +F+ NIKLG+ ED  NR ++A+ LRF S++  ++ T+L  Y+ RMKE Q  IYY+ G S+  V  S FVERL  +G+EVL + + +DEY +Q + EY+ KK   V KEG+ + + E  K+  +  +  F+PL   +K+  L   +EK  VS RLV SP  +V S +GWS NMERIMK+QA    +D +   Y   KK  EINP H ++K L  RV A + D +      LLFET+ L SGFSL+D     +RI  +++  L +  D
Sbjct:  243 VNNVKPIWMRKPNQVEEDEYKQFYKSITKDSEEPLSHVHFSAEGEVSFRSILYVPKKSPNDMFQNYGKVIENIKLYVRRVFITDDFADMLPKYLSFIRGIVDSDDLPLNVSRENLQQHKLLKVIKKKLVRKVLDMLKKL--DGAQFDDFWSEFSTNIKLGVMEDPSNRMRLAKLLRFQSSNDADKTTTLAAYVERMKEKQDAIYYMAGTSRKEVETSPFVERLIAKGYEVLFLTEAVDEYCIQAMPEYESKKFQNVAKEGVTIDDGEKAKEAHKGLEEEFKPLTDWLKETALKDLIEKAVVSQRLVKSPSALVASSYGWSGNMERIMKSQAYAKAKDPTQDFYATQKKTFEINPRHPVIKELLKRVTASEEDTTAASTAKLLFETATLRSGFSLQDQVGFADRIEAVLRQSLDVSQD 657          

HSP 2 Score: 197.593 bits (501), Expect = 1.924e-53
Identity = 105/198 (53.03%), Postives = 141/198 (71.21%), Query Frame = 2
Query:  242 LMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADIS-----MIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYD-NSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            +M LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTDP  L   +++ +KI  D++   L I DTG+GMT+ DLINNLGTIARSGT  F+  L   A  S     +IGQFGVGFY+++LVAD+V V +K+NDD+QY+WES +  SFTI  D     + RG+++ LY+KE+  ++L+   +K ++ K+SQFI + I L
Sbjct:    1 MMKLIINSLYRNKEIFLRELISNASDALDKIRLLSLTDPEQLRETEEMSVKIKADRENRLLHITDTGVGMTRQDLINNLGTIARSGTSEFLSKLMDTATSSDQQQDLIGQFGVGFYAAFLVADRVVVTTKNNDDDQYIWESDS-ASFTISKDPRGNTLKRGTQITLYLKEEAADFLEPDTLKNLVHKYSQFINFDIFL 197          
BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0332873)

HSP 1 Score: 675.626 bits (1742), Expect = 0.000e+0
Identity = 343/444 (77.25%), Postives = 390/444 (87.84%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDD--VEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFY+QF+KN+KLG+HEDS NR K+A+FLRF++++SG++  SL DY+SRMK+NQK +Y+ITGESKD V +SAFVER+  RGFEV+ M +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH I+++L+ + DADKNDK+VKDLV+LLFETSLLSSGFSL+ PQVH +RI+RMIKLGLGI++D+     DA  AGD P     TED A  MEEVD
Sbjct:  275 LNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTED-ASHMEEVD 717          

HSP 2 Score: 365.155 bits (936), Expect = 9.103e-115
Identity = 179/216 (82.87%), Postives = 206/216 (95.37%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            +AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L IK+IP+K AGTLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV V SK+NDDEQY+WESSAGGSFT++ DNSEP+GRG+K++LY+KEDQ +YL+E KIKEI+ KHSQFIGYPIKL++EKER+KE+S
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVS 219          
BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Hsp83 (gene:FBgn0001233 transcript:FBtr0073040)

HSP 1 Score: 675.626 bits (1742), Expect = 0.000e+0
Identity = 343/444 (77.25%), Postives = 390/444 (87.84%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDD--VEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFY+QF+KN+KLG+HEDS NR K+A+FLRF++++SG++  SL DY+SRMK+NQK +Y+ITGESKD V +SAFVER+  RGFEV+ M +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH I+++L+ + DADKNDK+VKDLV+LLFETSLLSSGFSL+ PQVH +RI+RMIKLGLGI++D+     DA  AGD P     TED A  MEEVD
Sbjct:  275 LNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYDQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLADYVSRMKDNQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDESEKKKREEDKAKFESLCKLMKSILDNKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVETLRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTDDAQSAGDAPSLVEDTED-ASHMEEVD 717          

HSP 2 Score: 365.155 bits (936), Expect = 9.103e-115
Identity = 179/216 (82.87%), Postives = 206/216 (95.37%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            +AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L IK+IP+K AGTLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV V SK+NDDEQY+WESSAGGSFT++ DNSEP+GRG+K++LY+KEDQ +YL+E KIKEI+ KHSQFIGYPIKL++EKER+KE+S
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVTVTSKNNDDEQYVWESSAGGSFTVRADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVS 219          
BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Gp93 (gene:FBgn0039562 transcript:FBtr0085254)

HSP 1 Score: 340.502 bits (872), Expect = 9.624e-105
Identity = 194/414 (46.86%), Postives = 281/414 (67.87%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFEN-KKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDI-LDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALR---DSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI 2236
            +N +KPIWTR P +V++++Y  FYKSLT D  + L   HF  EG++ F++LL+ PK  P + F     K +NIKLYVRRVFI D   D++P YL+F++GVVDS+DLPLN+SRE LQQ+K++KVI+K LV+K L++ ++I  DK+ Y+KF+++F+ NIKLG+ ED  NR+++A+ LRF  TS+G+ +TSL +Y  RMK  Q+ IYYI G ++  V  S FVERL  +G+EVL +V+ +DEY +  L E+DGKK   V KEG +L E E  KK FE  K+ FEPL K + D+ L  ++ K  VS RL +SPC +V   FGW+ NMER+  + A +   D     Y+  KK LEINP H +M+ L  RV+AD+ D + KD+ +++F T+ L SG+ L++     + I +M++  LG+
Sbjct:  336 INDSKPIWTRKPAEVTEDEYTSFYKSLTKDSSEPLTQTHFIAEGEVTFKSLLYVPKVQPSESFNRYGTKSDNIKLYVRRVFITDEFNDMMPNYLSFIRGVVDSDDLPLNVSRETLQQHKLIKVIKKKLVRKVLDMLKKI--DKEAYEKFWKEFSTNIKLGVMEDPSNRSRLAKLLRF-QTSNGKGVTSLAEYKERMKAKQEHIYYIAGANRAEVEKSPFVERLLSKGYEVLYLVEAVDEYCISALPEFDGKKFQNVAKEGFQLNESEKSKKNFESLKSTFEPLVKWLNDVALKDQISKAQVSERLSNSPCALVAGVFGWTGNMERLAMSNAHQKSDDPQRTYYLNQKKTLEINPRHPLMRELLRRVEADEADDTAKDMAVMMFRTATLRSGYMLQETSQFADSIEQMMRQTLGV 746          

HSP 2 Score: 206.068 bits (523), Expect = 1.088e-55
Identity = 111/211 (52.61%), Postives = 156/211 (73.93%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQ-----AGADIS-MIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYD-NSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            A+ F FQ E+ ++M LIIN+ Y NKEIFLRELISN+SDA+DKIR  +L++   L++  +L I+I  DK+   L I+D+GIGMT  DLINNLGTIA+SGT  F+  +Q      G D++ MIGQFGVGFYS++LVAD+V V +K NDD+QY+WES A  SF+I  D   + + RGS + LY+KE+  ++L+E  ++E+I+K+SQFI +PI++
Sbjct:   72 AKKFTFQTEVNRMMKLIINSLYRNKEIFLRELISNASDAIDKIRLLALSNSKELETNPELHIRIKADKENKALHIMDSGIGMTHQDLINNLGTIAKSGTADFLAKMQDPSKSEGLDMNDMIGQFGVGFYSAFLVADRVVVTTKHNDDKQYIWESDA-NSFSITEDPRGDTLKRGSVISLYLKEEAQDFLEEDTVRELIRKYSQFINFPIRM 281          
BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0086149)

HSP 1 Score: 177.178 bits (448), Expect = 2.513e-46
Identity = 125/406 (30.79%), Postives = 215/406 (52.96%), Query Frame = 2
Query: 1013 NKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNN-IKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDK-DNYKKFYEQFAKNIKLGI--HEDSVNRNKIAEFLRFYS----TSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXX---XXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSL-KLRVDADKNDKSVKDLVM-LLFETSLLSSGFSLEDPQV 2191
            N+ KP+W   P  +S+E + +FY+ ++N ++      H++ +  L   ALL+ P+  P  LFE  +  N  + LY R+V I    E L+P++L FVKGVVDSED+PLN+SRE+LQ + +++ +   +  + +   +E  + + + Y+ FY  +   +K GI    D+  + +IA+ LRF S    T+SG    SL++Y + +   Q++IYY+   ++     S + E L KR   VL   +P DE  + QL ++  KKLV V KE  E  ++        +    ++  + L   +++ L  +V KV  + RL + PC I   +    A     ++ Q+ +      +   +  LEINP H I+K L KLR    ++DK +  L+   LF  +++ +G + EDP++
Sbjct:  281 NEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGR--MSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKVKATTRLDTHPCVITVEEM---AAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKKLNKLR----ESDKDLAQLIAKQLFANAMVGAGLA-EDPRM 675          

HSP 2 Score: 160.614 bits (405), Expect = 1.007e-40
Identity = 97/208 (46.63%), Postives = 138/208 (66.35%), Query Frame = 2
Query:  221 FQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKD--LMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEAL---QAG----ADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            FQAE  QL+ ++  + YS+ E+F+RELISN+SDAL+K RY SL+      + KD  L I+I  DK    L I DTGIGMTK +L++NLGTIARSG+K F+E +   Q G    A  ++IGQFGVGFYSS++VA+KV+V +++          S  GS T + +    +  G++++L++K D  EY DE++IK +IKK+S F+G PI L
Sbjct:   68 FQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVPDVELGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275          
BLAST of Heat shock protein 90 vs. Ensembl Fly
Match: Trap1 (gene:FBgn0026761 transcript:FBtr0336666)

HSP 1 Score: 177.178 bits (448), Expect = 2.513e-46
Identity = 125/406 (30.79%), Postives = 215/406 (52.96%), Query Frame = 2
Query: 1013 NKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNN-IKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDK-DNYKKFYEQFAKNIKLGI--HEDSVNRNKIAEFLRFYS----TSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXX---XXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSL-KLRVDADKNDKSVKDLVM-LLFETSLLSSGFSLEDPQV 2191
            N+ KP+W   P  +S+E + +FY+ ++N ++      H++ +  L   ALL+ P+  P  LFE  +  N  + LY R+V I    E L+P++L FVKGVVDSED+PLN+SRE+LQ + +++ +   +  + +   +E  + + + Y+ FY  +   +K GI    D+  + +IA+ LRF S    T+SG    SL++Y + +   Q++IYY+   ++     S + E L KR   VL   +P DE  + QL ++  KKLV V KE  E  ++        +    ++  + L   +++ L  +V KV  + RL + PC I   +    A     ++ Q+ +      +   +  LEINP H I+K L KLR    ++DK +  L+   LF  +++ +G + EDP++
Sbjct:  281 NEIKPLWLLEPQSISKEQHHDFYRFISNSFDVPRFTLHYNADVPLSIHALLYFPEGKP-GLFEMSRDGNTGVALYTRKVLIQSKTEHLLPKWLRFVKGVVDSEDIPLNLSRELLQNSSLIRKLSSVISTRVIRFLQERSKKQPEEYEAFYRDYGLFLKEGIVTSSDASEKEEIAKLLRFESSKSETASGR--MSLEEYYNAVPAEQQNIYYLAAPNRVLAESSPYYESLKKRNELVLFCYEPYDELVLMQLGKFKSKKLVSVEKEMREESKETTATTDFGEGSLLRSELDTLIPWLEEELRGQVIKVKATTRLDTHPCVITVEEM---AAARHFIRTQSHQVPEQNRFALLQPELEINPKHPIIKKLNKLR----ESDKDLAQLIAKQLFANAMVGAGLA-EDPRM 675          

HSP 2 Score: 160.614 bits (405), Expect = 1.007e-40
Identity = 97/208 (46.63%), Postives = 138/208 (66.35%), Query Frame = 2
Query:  221 FQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKD--LMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEAL---QAG----ADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            FQAE  QL+ ++  + YS+ E+F+RELISN+SDAL+K RY SL+      + KD  L I+I  DK    L I DTGIGMTK +L++NLGTIARSG+K F+E +   Q G    A  ++IGQFGVGFYSS++VA+KV+V +++          S  GS T + +    +  G++++L++K D  EY DE++IK +IKK+S F+G PI L
Sbjct:   68 FQAETRQLLDIVARSLYSDHEVFVRELISNASDALEKFRYTSLSAGGENLAGKDRPLEIRITTDKPLMQLIIQDTGIGMTKEELVSNLGTIARSGSKKFLEQMKGTQQGASSEASSNIIGQFGVGFYSSFIVANKVEVFTRAAVPNAPGLRWSTDGSGTYEIEEVPDVELGTRIVLHLKTDCREYADEERIKAVIKKYSNFVGSPILL 275          
BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 342/445 (76.85%), Postives = 395/445 (88.76%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCL+LF E+ EDKDNYKK+YEQF+KNIKLGIHEDS NR K+++ LR+Y+++SG+EM SLKDY+SRMK+ QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKEYDGK LV VTKEGLELPEDE+EKKK +E KA +E LCK+MKDILDKK+EKVTVSNRLVSSPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGF+L+DPQ H NRI+RMIKLGLGI+DDD    EI      D+PV     +D+  +MEEVD
Sbjct:  283 LNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDDSVVEEISQPAEEDMPV--LEGDDDTSRMEEVD 725          

HSP 2 Score: 346.28 bits (887), Expect = 1.908e-107
Identity = 175/217 (80.65%), Postives = 200/217 (92.17%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS KDL I++IPD+   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+K D  E IGRG+KVIL++KEDQ EY++EK+IKE++KKHSQFIGYPI L +EK+R+KE+
Sbjct:   11 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEV 227          
BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90aa1.1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 [Source:NCBI gene;Acc:30591])

HSP 1 Score: 681.019 bits (1756), Expect = 0.000e+0
Identity = 342/445 (76.85%), Postives = 395/445 (88.76%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCL+LF E+ EDKDNYKK+YEQF+KNIKLGIHEDS NR K+++ LR+Y+++SG+EM SLKDY+SRMK+ QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKEYDGK LV VTKEGLELPEDE+EKKK +E KA +E LCK+MKDILDKK+EKVTVSNRLVSSPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGF+L+DPQ H NRI+RMIKLGLGI+DDD    EI      D+PV     +D+  +MEEVD
Sbjct:  283 LNKTKPIWTRNPDDITNEEYGEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLDLFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSDLLRYYTSASGDEMVSLKDYVSRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLVSVTKEGLELPEDEEEKKKQDELKAKYENLCKIMKDILDKKIEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPAHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLDDPQTHANRIYRMIKLGLGIDDDDSVVEEISQPAEEDMPV--LEGDDDTSRMEEVD 725          

HSP 2 Score: 346.28 bits (887), Expect = 1.908e-107
Identity = 175/217 (80.65%), Postives = 200/217 (92.17%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS KDL I++IPD+   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+K D  E IGRG+KVIL++KEDQ EY++EK+IKE++KKHSQFIGYPI L +EK+R+KE+
Sbjct:   11 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKDLKIELIPDQKERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDFGESIGRGTKVILHLKEDQSEYVEEKRIKEVVKKHSQFIGYPITLYIEKQREKEV 227          
BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 351/445 (78.88%), Postives = 398/445 (89.44%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI-EDDDVEIDATEAGDIP--VGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDKDNYKKFY+ F+KN+KLGIHEDS NR K++E LR+ S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD V HSAFVER+ KRGFEVL M +PIDEY VQQLK++DGK LV VTKEGLELPEDEDEKKK EE KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH IM++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI ED+DV ++   +   P  + P   +D+A +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPPLEGDDDASRMEEVD 725          

HSP 2 Score: 348.206 bits (892), Expect = 3.786e-108
Identity = 174/213 (81.69%), Postives = 197/213 (92.49%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLREL+SN+SDALDKIRY+SLTDP+ LDS KDL I IIP+    TLT++DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D+ EPIGRG+KVIL++KEDQ EY++EK++KE++KKHSQFIGYPI L +EKERDKEIS
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEIS 225          
BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 351/445 (78.88%), Postives = 398/445 (89.44%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI-EDDDVEIDATEAGDIP--VGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDKDNYKKFY+ F+KN+KLGIHEDS NR K++E LR+ S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD V HSAFVER+ KRGFEVL M +PIDEY VQQLK++DGK LV VTKEGLELPEDEDEKKK EE KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH IM++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI ED+DV ++   +   P  + P   +D+A +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDISNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYDAFSKNLKLGIHEDSQNRKKLSELLRYQSSQSGDEMTSLTEYVSRMKENQKSIYYITGESKDQVAHSAFVERVCKRGFEVLYMTEPIDEYCVQQLKDFDGKSLVSVTKEGLELPEDEDEKKKMEEDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDEDVPVEEPSSAAAPEDIPPLEGDDDASRMEEVD 725          

HSP 2 Score: 348.206 bits (892), Expect = 3.786e-108
Identity = 174/213 (81.69%), Postives = 197/213 (92.49%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLREL+SN+SDALDKIRY+SLTDP+ LDS KDL I IIP+    TLT++DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K D+ EPIGRG+KVIL++KEDQ EY++EK++KE++KKHSQFIGYPI L +EKERDKEIS
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELVSNASDALDKIRYESLTDPTKLDSGKDLKIDIIPNVQERTLTLIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDHGEPIGRGTKVILHLKEDQTEYIEEKRVKEVVKKHSQFIGYPITLYVEKERDKEIS 225          
BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Match: hsp90aa1.2 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 665.611 bits (1716), Expect = 0.000e+0
Identity = 343/445 (77.08%), Postives = 399/445 (89.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPV---GPTSTEDEAGKMEEVD 2335
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNC++LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK+YEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY++RMK+ QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K+ FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH I+++L+ + +ADKNDKSVKDLV+LLFET+LLSSGF+L+DPQ H NRI+RMIKLGLGI++DD  + A E    P+    P   +D+  +MEEVD
Sbjct:  292 LNKTKPLWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKDNYKKYYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEEKKSKFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIVETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLDDPQTHSNRIYRMIKLGLGIDEDD--LSAEEPSSAPIEEMPPLEGDDDTSRMEEVD 734          

HSP 2 Score: 358.992 bits (920), Expect = 4.311e-112
Identity = 182/220 (82.73%), Postives = 204/220 (92.73%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M + + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS KDL I+IIP+K+  TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K  DDEQY WESSAGGSFT+K DNSEPIGRG+KVIL++KEDQ EY++E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   10 MEDEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHLDDEQYAWESSAGGSFTVKVDNSEPIGRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 229          
BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 991.49 bits (2562), Expect = 0.000e+0
Identity = 542/717 (75.59%), Postives = 627/717 (87.45%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG----DIPVGPTSTEDEAGKMEEVD 2335
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LDS K+L I +IP++   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ DN+EP+GRG+KVIL++KEDQ EYL+E++IKEI+K+HSQFIGYPI L +EKERDKEISDDE+E    ++K+ +  + + +    D+EED  K DK KK KKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KNIKLGIHEDS NR K++E LR+YS++SG+EM SL +Y+SRMKENQK IYYITGE+KD V HSAFVE L K G EV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE+K  FE LCKV+K+ILDKKVEKV +SNRLV SPCCIVTS +GWSANMERIMKAQALRD+STMGYMAAKKHLEIN DH I+++L+ + +ADKNDKSVKDLV LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI++D    +  E      D+P  P   +++A +MEEVD
Sbjct:    6 EDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSNRLVESPCCIVTSTYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 720          
BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 991.104 bits (2561), Expect = 0.000e+0
Identity = 542/717 (75.59%), Postives = 627/717 (87.45%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG----DIPVGPTSTEDEAGKMEEVD 2335
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LDS K+L I +IP++   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ DN+EP+GRG+KVIL++KEDQ EYL+E++IKEI+K+HSQFIGYPI L +EKERDKEISDDE+E    ++K+ +  + + +    D+EED  K DK KK KKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KNIKLGIHEDS NR K++E LR+YS++SG+EM SL +Y+SRMKENQK IYYITGE+KD V HSAFVE L K G EV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE+K  FE LCKV+K+ILDKKVEKV +SNRLV SPCCIVTS +GWSANMERIMKAQALRD+STMGYMAAKKHLEIN DH I+++L+ + +ADKNDKSVKDLV LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI++D    +  E      D+P  P   +++A +MEEVD
Sbjct:    2 EDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSNRLVESPCCIVTSTYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 716          
BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 972.615 bits (2513), Expect = 0.000e+0
Identity = 536/717 (74.76%), Postives = 620/717 (86.47%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG----DIPVGPTSTEDEAGKMEEVD 2335
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LDS K+L I +IP++   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ DN+EP+GRG+KVIL++KEDQ EYL+E++IKEI+K+HSQFIGYPI L        EISDDE+E    ++K+ +  + + +    D+EED  K DK KK KKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KNIKLGIHEDS NR K++E LR+YS++SG+EM SL +Y+SRMKENQK IYYITGE+KD V HSAFVE L K G EV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE+K  FE LCKV+K+ILDKKVEKV +SNRLV SPCCIVTS +GWSANMERIMKAQALRD+STMGYMAAKKHLEIN DH I+++L+ + +ADKNDKSVKDLV LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI++D    +  E      D+P  P   +++A +MEEVD
Sbjct:    9 EDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLY-------EISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSNRLVESPCCIVTSTYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 716          
BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 935.636 bits (2417), Expect = 0.000e+0
Identity = 524/717 (73.08%), Postives = 608/717 (84.80%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG----DIPVGPTSTEDEAGKMEEVD 2335
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LDS K+L I +IP++   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ DN+EP+GRG+KVIL++KEDQ EYL+E++IKEI+K+HSQFIGYPI L +EKERDKEISDDE+E    ++K+ +  + + +    D+EED  K DK KK KKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KNIKLGIHEDS NR K++E LR+YS++SG+EM SL +Y+SRMKENQK IYYITGE+KD V HSAFVE L K G EV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE+K  FE LCKV+K+ILDKKVEKV +SN                     RIMKAQALRD+STMGYMAAKKHLEIN DH I+++L+ + +ADKNDKSVKDLV LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI++D    +  E      D+P  P   +++A +MEEVD
Sbjct:    2 EDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVLLSN---------------------RIMKAQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 695          
BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Match: ccdc173 (coiled-coil domain containing 173 [Source:Xenbase;Acc:XB-GENE-6258504])

HSP 1 Score: 923.694 bits (2386), Expect = 0.000e+0
Identity = 519/717 (72.38%), Postives = 605/717 (84.38%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG----DIPVGPTSTEDEAGKMEEVD 2335
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRE+ISNSSDALDKIRY+SLTDPS LDS K+L I +IP++   TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K +DDEQY WESSAGGSFT++ DN+EP+GRG+KVIL++KEDQ EYL+E++IKEI+K+HSQFIGYPI L +EKERDKEISDDE+E    ++K+ +  + + +    D+EED  K DK KK KKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFS+EGQLEFRALLF P+RAPFDLFE+KKK+NNIKLYVRRVFIMDNCE+LIPEYLN +KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKK YEQF+KNIKLGIHEDS NR K++E LR+YS++SG+EM SL +Y+SRMKENQK IYYITGE+KD V HSAFVE L K G EV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE+K  FE LCKV+K+ILDKKVEKV +    + SP                   +QALRD+STMGYMAAKKHLEIN DH I+++L+ + +ADKNDKSVKDLV LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI++D    +  E      D+P  P   +++A +MEEVD
Sbjct:    2 EDEVETFAFQAEIAQLMSLIINTFYSNKEIFLREIISNSSDALDKIRYESLTDPSKLDSGKELKIDLIPNRRDRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHSDDEQYAWESSAGGSFTVRADNTEPLGRGTKVILHLKEDQTEYLEERRIKEIVKRHSQFIGYPITLYMEKERDKEISDDESEEQIDEKKDEKKDKTEIEDVGSDEEEDAKKGDKKKKTKKIKEKYIDQEELNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSIEGQLEFRALLFVPRRAPFDLFESKKKKNNIKLYVRRVFIMDNCEELIPEYLNIIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKENYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYSSASGDEMISLSEYVSRMKENQKHIYYITGETKDQVSHSAFVEGLRKHGLEVIYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKVIKEILDKKVEKVVII--FLESP-------------------SQALRDNSTMGYMAAKKHLEINCDHPIIETLRQKAEADKNDKSVKDLVNLLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDEDSFAEEEEEESPAIQDMP--PLEGDEDASRMEEVD 695          
BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 689.878 bits (1779), Expect = 0.000e+0
Identity = 344/445 (77.30%), Postives = 400/445 (89.89%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IY+ITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD  +D T A    ++P  P   +D+  +MEEVD
Sbjct:  291 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP--PLEGDDDTSRMEEVD 733          

HSP 2 Score: 355.91 bits (912), Expect = 5.106e-111
Identity = 180/220 (81.82%), Postives = 200/220 (90.91%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231          
BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 689.878 bits (1779), Expect = 0.000e+0
Identity = 344/445 (77.30%), Postives = 400/445 (89.89%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IY+ITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD  +D T A    ++P  P   +D+  +MEEVD
Sbjct:  291 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYFITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTVDDTSAAVTEEMP--PLEGDDDTSRMEEVD 733          

HSP 2 Score: 355.91 bits (912), Expect = 5.106e-111
Identity = 180/220 (81.82%), Postives = 200/220 (90.91%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231          
BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90ab1 (heat shock protein 90 alpha (cytosolic), class B member 1 [Source:MGI Symbol;Acc:MGI:96247])

HSP 1 Score: 662.529 bits (1708), Expect = 0.000e+0
Identity = 340/444 (76.58%), Postives = 399/444 (89.86%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIP--VGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+C++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KN+KLGIHEDS NR +++E LR++++ SG+EMTSL +Y+SRMKE QK IYYITGESK+ V +SAFVER+ KRGFEV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK EE KA FE LCK+MK+ILDKKVEKVT+SNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++D+V  +   A  +P  + P   +++A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYKKFYEAFSKNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQVANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELPEDEEEKKKMEESKAKFENLCKLMKEILDKKVEKVTISNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIVETLRQKAEADKNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNRIYRMIKLGLGIDEDEVTAEEPSAA-VPDEIPPLEGDEDASRMEEVD 724          

HSP 2 Score: 348.591 bits (893), Expect = 2.645e-108
Identity = 175/213 (82.16%), Postives = 197/213 (92.49%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L I IIP+    TLT+VDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D+ EPIGRG+KVIL++KEDQ EYL+E+++KE++KKHSQFIGYPI L LEKER+KEIS
Sbjct:   14 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNPQERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVRADHGEPIGRGTKVILHLKEDQTEYLEERRVKEVVKKHSQFIGYPITLYLEKEREKEIS 226          
BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1 [Source:MGI Symbol;Acc:MGI:98817])

HSP 1 Score: 385.185 bits (988), Expect = 2.343e-121
Identity = 203/416 (48.80%), Postives = 285/416 (68.51%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFE--NKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKD-ILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIE 2239
            +N  KPIW R   +V +++Y  FYKS + + +D +A  HF+ EG++ F+++LF P  AP  LF+    KK + IKLYVRRVFI D+  D++P+YLNFVKGVVDS+DLPLN+SRE LQQ+K+LKVIRK LV+K L++ ++I ++K N   F+++F  NIKLG+ ED  NR ++A+ LRF S+    ++TSL  Y+ RMKE Q  IY++ G S+     S FVERL K+G+EV+ + +P+DEY +Q L E+DGK+   V KEG++  E E  K+  E  +  FEPL   MKD  L  K+EK  VS RL  SPC +V SQ+GWS NMERIMKAQA    +D ST  Y + KK  EINP H +++ +  R+  D++DK+V DL ++LFET+ L SG+ L D + +G+RI RM++L L I+
Sbjct:  336 MNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADEKYN-DTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHSTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREATEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVMDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNID 750          

HSP 2 Score: 203.756 bits (517), Expect = 8.995e-55
Identity = 108/207 (52.17%), Postives = 146/207 (70.53%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFM----EALQAGADIS-MIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPI 811
            +E FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTD + L   ++L +KI  DK+   L + DTG+GMT+ +L+ NLGTIA+SGT  F+    EA + G   S +IGQFGVGFYS++LVADKV V SK N+D Q++WES +     I       +GRG+ + L +KE+  +YL+   IK +++K+SQFI +PI
Sbjct:   73 SEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALAGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVRKYSQFINFPI 279          
BLAST of Heat shock protein 90 vs. Ensembl Mouse
Match: Hsp90aa1 (heat shock protein 90, alpha (cytosolic), class A member 1 [Source:MGI Symbol;Acc:MGI:96250])

HSP 1 Score: 319.701 bits (818), Expect = 4.214e-104
Identity = 155/188 (82.45%), Postives = 170/188 (90.43%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLD 754
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPSKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLE 199          
BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P04809|HSP83_DROPS (Heat shock protein 83 OS=Drosophila pseudoobscura pseudoobscura OX=46245 GN=Hsp83 PE=3 SV=2)

HSP 1 Score: 995.342 bits (2572), Expect = 0.000e+0
Identity = 536/715 (74.97%), Postives = 621/715 (86.85%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVL--EKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDD--VEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            +AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS K+L IK+IP+K AGTLTI+DTGIGMTK+DL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YL+AD+V V SK+NDDEQY+WESSAGGSFT+K DNSEP+GRG+K++LY+KEDQ +YL+E KIKEI+ KHSQFIGYPIKL++  E+E++    + + E  D + K+  DT++    +  +DE+ D K    KKKK IKEKY ++EELNKTKPIWTRNPDD+SQE+Y EFYKSLTNDWEDHL VKHFSVEGQLEFRALLF P+R PFDLFEN+KKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNK+LKVIRKNLVKK +EL EE+ EDK+NYKKFYEQF+KN+KLG+HEDS NR K+A+FLRF++++SG++  SL DY+SRMKENQK +Y+ITGESKD V +SAFVER+  RGFEV+ M +PIDEY +Q LKEY GK+LV VTKEGLELPEDE EKKK EE KA FE LCK+MK ILD KVEKV VSNRLV SPCCIVTSQFGWSANMERIMKAQALRD++TMGYMA KK LEINPDH I+++L+ + DADKNDK+VKDLV+LLFETSLLSSGFSL+ PQVH +RI+RMIKLGLGI++D+     DA   GD P     TED A  MEEVD
Sbjct:    4 EAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKELYIKLIPNKTAGTLTIIDTGIGMTKSDLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVTVTSKNNDDEQYVWESSAGGSFTVKADNSEPLGRGTKIVLYIKEDQTDYLEESKIKEIVNKHSQFIGYPIKLLVEKEREKEVSDDEADDEKKDDEAKKDMDTDEPKIEDVGEDEDADKKDKDGKKKKTIKEKYTEDEELNKTKPIWTRNPDDISQEEYGEFYKSLTNDWEDHLCVKHFSVEGQLEFRALLFIPRRTPFDLFENQKKRNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQNKVLKVIRKNLVKKTMELIEELTEDKENYKKFYEQFSKNLKLGVHEDSNNRAKLADFLRFHTSASGDDFCSLSDYVSRMKENQKHVYFITGESKDQVSNSAFVERVKARGFEVVYMTEPIDEYVIQHLKEYKGKQLVSVTKEGLELPEDEAEKKKREEDKAKFEGLCKLMKSILDSKVEKVVVSNRLVDSPCCIVTSQFGWSANMERIMKAQALRDTATMGYMAGKKQLEINPDHPIVEALRQKADADKNDKAVKDLVILLFETSLLSSGFSLDSPQVHASRIYRMIKLGLGIDEDEPMTTEDAHSGGDAPGLVEDTED-ASHMEEVD 717          
BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|O61998|HSP90_BRUPA (Heat shock protein 90 OS=Brugia pahangi OX=6280 GN=HSP90 PE=2 SV=2)

HSP 1 Score: 697.967 bits (1800), Expect = 0.000e+0
Identity = 355/447 (79.42%), Postives = 405/447 (90.60%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI-EDDDVEIDATEAGD----IPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+S E+YAEFYKSL+NDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK +N IKLYVRRVFIM+NC++L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF+EI EDKDN+KKFYEQF+KNIKLGIHEDS NR K++EFLRFY+++S EEMTSLKDY+SRMKENQK IY+ITGES++ V  SAFVER+ +RGFEV+ M DPIDEY VQQLKEYDGKKLV VTKEGLELPE E+EKKKFEE K  FE LCKVMKDIL+KKVEKV VSNRLVSSPCCIVTS++GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS++K+L+ RV+ADKNDK+VKDLV+LLFET+LLSSGFSLEDPQ+H +RI+RMIKLGL I ED++ E  A+ +G+    +P      E++A +MEEVD
Sbjct:  272 LNKTKPIWTRNPDDISNEEYAEFYKSLSNDWEDHLAVKHFSVEGQLEFRALLFVPQRAPFDLFENKKTKNAIKLYVRRVFIMENCDELMPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFDEIAEDKDNFKKFYEQFSKNIKLGIHEDSTNRKKLSEFLRFYTSASSEEMTSLKDYVSRMKENQKQIYFITGESREAVASSAFVERVKRRGFEVIYMTDPIDEYCVQQLKEYDGKKLVSVTKEGLELPESEEEKKKFEEDKVKFENLCKVMKDILEKKVEKVAVSNRLVSSPCCIVTSEYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVIKALRERVEADKNDKTVKDLVVLLFETALLSSGFSLEDPQLHASRIYRMIKLGLDITEDEEEEAIASVSGEKDECVP-NLVGAEEDASRMEEVD 717          

HSP 2 Score: 328.946 bits (842), Expect = 4.175e-100
Identity = 167/218 (76.61%), Postives = 194/218 (88.99%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY++LT+P+ L++ K+L IKI P+K   TLTI+DTGIGMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS++LVADKV V SK NDD+ Y WESSAGGSF I+  N   + RG+K+ LY+KEDQ +YL+E++IKEI+KKHSQFIGYPIKL +EKERDKE+S
Sbjct:    4 EMNGETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYQALTEPAELETGKELYIKITPNKADKTLTIMDTGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAFLVADKVVVASKHNDDDCYQWESSAGGSFIIRQVNDPELTRGTKITLYIKEDQTDYLEERRIKEIVKKHSQFIGYPIKLTVEKERDKEVS 221          
BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|A5A6K9|HS90A_PANTR (Heat shock protein HSP 90-alpha OS=Pan troglodytes OX=9598 GN=HSP90AA1 PE=2 SV=1)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 346/445 (77.75%), Postives = 399/445 (89.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD   D T A    ++P  P   +D+  +MEEVD
Sbjct:  291 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 733          

HSP 2 Score: 354.369 bits (908), Expect = 1.767e-109
Identity = 179/220 (81.36%), Postives = 200/220 (90.91%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVI ++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVIPHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231          
BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|Q4R4P1|HS90A_MACFA (Heat shock protein HSP 90-alpha OS=Macaca fascicularis OX=9541 GN=HSP90AA1 PE=2 SV=3)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 346/445 (77.75%), Postives = 399/445 (89.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD   D T A    ++P  P   +D+  +MEEVD
Sbjct:  291 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 733          

HSP 2 Score: 356.681 bits (914), Expect = 2.224e-110
Identity = 180/220 (81.82%), Postives = 201/220 (91.36%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231          
BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Match: sp|P07900|HS90A_HUMAN (Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5)

HSP 1 Score: 691.804 bits (1784), Expect = 0.000e+0
Identity = 346/445 (77.75%), Postives = 399/445 (89.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFEN+KK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDK+NYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY +RMKENQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+K  FE LCK+MKDIL+KKVEKV VSNRLV+SPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDHSI+++L+ + +ADKNDKSVKDLV+LL+ET+LLSSGFSLEDPQ H NRI+RMIKLGLGI++DD   D T A    ++P  P   +D+  +MEEVD
Sbjct:  290 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENRKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYCTRMKENQKHIYYITGETKDQVANSAFVERLRKHGLEVIYMIEPIDEYCVQQLKEFEGKTLVSVTKEGLELPEDEEEKKKQEEKKTKFENLCKIMKDILEKKVEKVVVSNRLVTSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHSIIETLRQKAEADKNDKSVKDLVILLYETALLSSGFSLEDPQTHANRIYRMIKLGLGIDEDDPTADDTSAAVTEEMP--PLEGDDDTSRMEEVD 732          

HSP 2 Score: 356.681 bits (914), Expect = 2.169e-110
Identity = 180/220 (81.82%), Postives = 201/220 (91.36%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            M E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I +IP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT++ D  EP+GRG+KVIL++KEDQ EYL+E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   12 MEEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELHINLIPNKQDRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVRTDTGEPMGRGTKVILHLKEDQTEYLEERRIKEIVKKHSQFIGYPITLFVEKERDKEVS 231          
BLAST of Heat shock protein 90 vs. TrEMBL
Match: C0KTP7 (90 kDa heat shock protein OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 1185.24 bits (3065), Expect = 0.000e+0
Identity = 659/715 (92.17%), Postives = 702/715 (98.18%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            MS+TD ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAK+LMIKIIPDKDAGTLTI+DTG+GMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLV+DKVQVISKSNDDEQ+LWESSAGGSFTI+ D+SE +GRG+K+ILYMKEDQIEYL+E+K+K+IIKKHSQFIGYPIKLVLEKERDKEISDDEAE + K++KE E TEDKPKIEDLDDEED++KK+KDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELFEEIMEDK+NYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSG++++SLK+Y+SRMKENQKDIYYITGESK+NV HSAFVERLTKRG EVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEK+KFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQ+GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPD SIMKSLK RVD+DKNDKSVKDLVMLL+ETSLLSSGF+LEDPQVHGNRIHRMIKLGLGIEDDDVE++ATEAGD+PV  ++TE++AGKMEEVD
Sbjct:    1 MSDTDTETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKELMIKIIPDKDAGTLTIIDTGVGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVSDKVQVISKSNDDEQFLWESSAGGSFTIRPDSSELLGRGTKIILYMKEDQIEYLEERKVKDIIKKHSQFIGYPIKLVLEKERDKEISDDEAEDEKKEDKEGESTEDKPKIEDLDDEEDENKKNKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCIELFEEIMEDKENYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGDDLSSLKEYVSRMKENQKDIYYITGESKENVCHSAFVERLTKRGLEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKEKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDRSIMKSLKTRVDSDKNDKSVKDLVMLLYETSLLSSGFTLEDPQVHGNRIHRMIKLGLGIEDDDVEMEATEAGDVPVVASTTEEDAGKMEEVD 715          
BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A1S3JGM6 (heat shock protein 83 OS=Lingula unguis OX=7574 GN=LOC106172755 PE=3 SV=1)

HSP 1 Score: 1035.79 bits (2677), Expect = 0.000e+0
Identity = 568/715 (79.44%), Postives = 646/715 (90.35%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPV--GPTSTEDEAGKMEEVD 2335
            E +AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L IKI+P+K   TLTI+DTG+GMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YL+AD+VQV SK NDDEQY+WESSAGGSFT++ D+ EP+GRG+K++LY+KEDQ EY++EK+IKE++KKHSQFIGYPIKLV+EKERDKE+SDDE E ++KKE E +D E     +  +D+ED+DK+   KKKKKIKEKY ++EELNKTKP+WTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF PKRAPFD+FENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKC+ELFEEI ED DN+KKFYEQF+KN+KLGIHEDS NR K++E LR+YS+ SG+EMTSLKDY SRMKENQK IYYITGESK+ V +SAFVERL KRG+EVL MVDPIDEYSVQQLKEYDGK LVCVTKEGLELPED++EKKKFEEQK AFEPLCK MK+ILDKKVEKV VSNRLVSSPCCIVTSQ+GWSANMERIMKAQALRD+STMGYMAAKKHLEINPDH+I+K+LK +V  DKNDKSVKDLV+L+FET+LLSSGF+LEDP  H +RIHRMIKLGLGI++DD         ++P   G    +D+A +MEEVD
Sbjct:   14 EGEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSGKELYIKIVPNKHNNTLTIIDTGVGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLIADRVQVTSKHNDDEQYVWESSAGGSFTVRQDHGEPLGRGTKIVLYLKEDQSEYMEEKRIKEVVKKHSQFIGYPIKLVVEKERDKEVSDDEEEEEEKKEGEEKDEEKPKVEDIGEDDEDEDKEKDGKKKKKIKEKYTEDEELNKTKPLWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPKRAPFDMFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCIELFEEIAEDADNFKKFYEQFSKNLKLGIHEDSTNRKKLSELLRYYSSHSGDEMTSLKDYTSRMKENQKVIYYITGESKETVANSAFVERLRKRGYEVLYMVDPIDEYSVQQLKEYDGKNLVCVTKEGLELPEDDEEKKKFEEQKEAFEPLCKTMKEILDKKVEKVVVSNRLVSSPCCIVTSQYGWSANMERIMKAQALRDNSTMGYMAAKKHLEINPDHAIIKNLKEKVAVDKNDKSVKDLVVLMFETALLSSGFTLEDPMHHASRIHRMIKLGLGIDEDDAAETPGPDEEMPPLEGEGEGDDDASRMEEVD 728          
BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A0M4HFL9 (Heat shock protein 90 OS=Macrostomum lignano OX=282301 GN=hsp90 PE=2 SV=1)

HSP 1 Score: 1033.48 bits (2671), Expect = 0.000e+0
Identity = 570/721 (79.06%), Postives = 646/721 (89.60%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVL--EKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDAT--EAGDIP--VGPTSTEDEAGKMEEVD 2335
            M++T+ ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDA+DKIRY+SLTD SVLDS +DL IKIIP+K   +LTI+D+GIGMTKADL+NNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYS+YLVAD+V V SK NDDEQY+WESSAGGSFT++ D+ EPIGRG+K++LY+KEDQ EY++E+K+KE+IKKHSQFIGYPIKLVL  E+E++    + E E ++KKE   +  ++KPK+ED  D+ D+D+K   KKKKKIKEKYIDEEELNKTKPIWTRN DD++QE+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF PKRAPFDLFEN+KKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELF++I EDK+N+KKFYEQF KN+KLGIHEDS NR K+A++LR+YSTSSG++ TSLKDY+SRMKENQKDIYYITGESK+ V HSAFVERL KRG EVL M DPIDEY+ QQL+EYDGKKLVCVTKEGLELPEDEDEKK FEE+KA+FEPLCKVMKDILDKKVEKV VSNRLV SPCCIVTSQ+GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSI   L+ R +ADKNDKSVKDLV LL+ET+LLSSGF+LEDPQVH  RIHRMIKLGLGIE+DDV   A    +  +P  VG  +  D+A KMEEVD
Sbjct:    1 MADTEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDAIDKIRYQSLTDSSVLDSGRDLEIKIIPNKSDNSLTIIDSGIGMTKADLVNNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVTSKHNDDEQYVWESSAGGSFTVRPDHGEPIGRGTKIVLYLKEDQTEYIEERKVKEVIKKHSQFIGYPIKLVLEKEREKEVSDDEAEEEKEEKKEDGEDAEKEKPKVEDDLDDNDEDEKGDKKKKKKIKEKYIDEEELNKTKPIWTRNQDDITQEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFENRKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFDDIAEDKENFKKFYEQFGKNLKLGIHEDSTNRKKLADYLRYYSTSSGDDWTSLKDYVSRMKENQKDIYYITGESKEAVAHSAFVERLRKRGLEVLYMTDPIDEYATQQLREYDGKKLVCVTKEGLELPEDEDEKKAFEEKKASFEPLCKVMKDILDKKVEKVVVSNRLVDSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSICGMLRQRTEADKNDKSVKDLVQLLYETALLSSGFALEDPQVHATRIHRMIKLGLGIEEDDVPDAAAGESSSSMPTEVGGDANADDA-KMEEVD 720          
BLAST of Heat shock protein 90 vs. TrEMBL
Match: A0A267DD20 (HATPase_c domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig023254g4 PE=3 SV=1)

HSP 1 Score: 1030.39 bits (2663), Expect = 0.000e+0
Identity = 571/721 (79.20%), Postives = 646/721 (89.60%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVL--EKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDAT--EAGDIP--VGPTSTEDEAGKMEEVD 2335
            M++T+ ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDA+DKIRY+SLTD SVLDS +DL IKIIP+K   +LTI+D+GIGMTKADL+NNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYS+YLVAD+V V SK NDDEQY+WESSAGGSFT++ D+ EPIGRG+K++LY+KEDQ EY++EKK+KE+IKKHSQFIGYPIKLVL  E+E++    + E E ++KKE   +  ++KPK+ED  D+ D+D+K   KKKKKIKEKYIDEEELNKTKPIWTRN DD++QE+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF PKRAPFDLFEN+KKRNNIKLYVRRVFIMDNCE+LIPEYLNF+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELF++I EDK+N+KKFYEQF KN+KLGIHEDS NR K+A++LR+YSTSSG++ TSLKDY+SRMKENQKDIYYITGESK+ V HSAFVERL KRG EVL M DPIDEY+ QQL+EYDGKKLVCVTKEGLELPEDEDEKK FEE+KA+FEPLCKVMKDILDKKVEKV VSNRLV SPCCIVTSQ+GWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSI   L+ R +ADKNDKSVKDLV LL+ET+LLSSGF+LEDPQVH  RIHRMIKLGLGIE+DDV   A    +  +P  VG  +  D+A KMEEVD
Sbjct:    1 MADTEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDAIDKIRYQSLTDSSVLDSGRDLEIKIIPNKSDNSLTIIDSGIGMTKADLVNNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADRVVVTSKHNDDEQYVWESSAGGSFTVRPDHGEPIGRGTKIVLYLKEDQTEYIEEKKVKEVIKKHSQFIGYPIKLVLEKEREKEVSDDEAEEEKEEKKEDGEDAEKEKPKVEDDLDDNDEDEKGDKKKKKKIKEKYIDEEELNKTKPIWTRNQDDITQEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFENRKKRNNIKLYVRRVFIMDNCEELIPEYLNFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFDDIAEDKENFKKFYEQFGKNLKLGIHEDSTNRKKLADYLRYYSTSSGDDWTSLKDYVSRMKENQKDIYYITGESKEAVAHSAFVERLRKRGLEVLYMTDPIDEYATQQLREYDGKKLVCVTKEGLELPEDEDEKKAFEEKKASFEPLCKVMKDILDKKVEKVVVSNRLVDSPCCIVTSQYGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSICGMLRQRTEADKNDKSVKDLVQLLYETALLSSGFALEDPQVHATRIHRMIKLGLGIEEDDVPDAAAGESSSSMPTEVGGDANADDA-KMEEVD 720          
BLAST of Heat shock protein 90 vs. TrEMBL
Match: E2B7J9 (Heat shock protein HSP 90-alpha OS=Harpegnathos saltator OX=610380 GN=EAI_02510 PE=3 SV=1)

HSP 1 Score: 1024.62 bits (2648), Expect = 0.000e+0
Identity = 558/712 (78.37%), Postives = 639/712 (89.75%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTE-DEAGKMEEVD 2335
            + ETFAFQAEIAQLMSLIINTFYSNKEIF+RELISN+SDALDKIRY+SLTDP+ LD+ K+L IKI+P+K+  TLTI+D+GIGMTKADL+NNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVADKV VISK NDDEQYLWESSAGGSFT++ DN EPIGRG+K+IL++KEDQ EYL+E KIKEI+KKHSQFIGYPIKLV+EKERDKE+S+DE E +  KE E+ED + K +    D++ED  K +K KKKK IKEKY ++EELNKTKPIWTRNPDD++QE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKK++NNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEE+ EDK+NYKK YEQF+KN+KLGIHEDS NR K++E LR+++++SG+EM SLKDY+ RMKENQK IYYITGES++ V +S+FVER+ KRGFEV+ M +PIDEY VQQLKE+DGK+LV VTKEGLELPEDEDEKKK EE KA FE LCKVMKDILDKKVEKV VSNRLV SPCCIVTSQ+GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH IM++L+ + +ADK+DKSVKDLVMLLFET+LLSSGF+LEDPQVH +RI+RMIKLGLG +DDDV     E  D  V P   + +EA +MEEVD
Sbjct:   12 EVETFAFQAEIAQLMSLIINTFYSNKEIFIRELISNASDALDKIRYESLTDPAKLDTCKELFIKIVPNKNDRTLTILDSGIGMTKADLVNNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVADKVIVISKHNDDEQYLWESSAGGSFTVRPDNGEPIGRGTKIILHIKEDQTEYLEESKIKEIVKKHSQFIGYPIKLVVEKERDKELSEDEEEEEPAKEAETEDEKPKIEDVGEDEDEDKPKDEKKKKKKTIKEKYTEDEELNKTKPIWTRNPDDITQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFIPRRAPFDLFENKKRKNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEELSEDKENYKKCYEQFSKNLKLGIHEDSQNRKKLSELLRYHTSASGDEMCSLKDYVGRMKENQKHIYYITGESREQVANSSFVERVKKRGFEVVYMTEPIDEYVVQQLKEFDGKQLVSVTKEGLELPEDEDEKKKREEDKAKFENLCKVMKDILDKKVEKVVVSNRLVDSPCCIVTSQYGWTANMERIMKAQALRDTSTMGYMAAKKHLEINPDHPIMENLRQKAEADKHDKSVKDLVMLLFETALLSSGFALEDPQVHASRIYRMIKLGLGFDDDDVPSTEDEKMDTEVPPLEGDSEEASRMEEVD 723          
BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 679.478 bits (1752), Expect = 0.000e+0
Identity = 344/446 (77.13%), Postives = 396/446 (88.79%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEID----ATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF EI EDKDNYKK YEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY+SRMK++QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKEYDGK L+ VTKEGLELPEDE+EKKK +E K  FE LCK+MKDILDKK+EKVTVSNRLV+SPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGF+LEDPQ H NRI+RMIKLGLGI+DDD  ++     TE  D+PV     +D+  +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEISEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGLELPEDEEEKKKQDELKTKFENLCKIMKDILDKKIEKVTVSNRLVASPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPLHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDDDDSAVEDILQPTEE-DMPV--LEGDDDTSRMEEVD 723          

HSP 2 Score: 346.665 bits (888), Expect = 1.111e-107
Identity = 175/217 (80.65%), Postives = 199/217 (91.71%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E D ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS L+S KDL I++IPD    TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY+WES+AGGSFT+K DN E IGRG+KVIL++KEDQ EY +EK+IKE++KKHSQFIGYPI L +EK+R+KE+
Sbjct:   11 EEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPDNGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLFVEKQREKEV 227          
BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 679.478 bits (1752), Expect = 0.000e+0
Identity = 344/446 (77.13%), Postives = 396/446 (88.79%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEID----ATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNCE+L+PEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF EI EDKDNYKK YEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY+SRMK++QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKEYDGK L+ VTKEGLELPEDE+EKKK +E K  FE LCK+MKDILDKK+EKVTVSNRLV+SPCCIVTS +GW+ANMERIMK+QALRD+STMGYM AKKHLEINP H I+++L+ + +ADKNDK+VKDLV+LLFET+LLSSGF+LEDPQ H NRI+RMIKLGLGI+DDD  ++     TE  D+PV     +D+  +MEEVD
Sbjct:  281 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCEELMPEYLNFMKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTEISEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSNSGDEMVSLKDYVSRMKDSQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEYDGKNLLSVTKEGLELPEDEEEKKKQDELKTKFENLCKIMKDILDKKIEKVTVSNRLVASPCCIVTSTYGWTANMERIMKSQALRDNSTMGYMTAKKHLEINPLHPIVETLREKAEADKNDKAVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDDDDSAVEDILQPTEE-DMPV--LEGDDDTSRMEEVD 723          

HSP 2 Score: 346.665 bits (888), Expect = 1.111e-107
Identity = 175/217 (80.65%), Postives = 199/217 (91.71%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E D ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS L+S KDL I++IPD    TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY+WES+AGGSFT+K DN E IGRG+KVIL++KEDQ EY +EK+IKE++KKHSQFIGYPI L +EK+R+KE+
Sbjct:   11 EEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLESCKDLKIELIPDLKNRTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVTVITKHNDDEQYVWESAAGGSFTVKPDNGESIGRGTKVILHLKEDQSEYTEEKRIKEVVKKHSQFIGYPITLFVEKQREKEV 227          
BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:103047517])

HSP 1 Score: 674.085 bits (1738), Expect = 0.000e+0
Identity = 347/444 (78.15%), Postives = 398/444 (89.64%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIP--VGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLA+KHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMD+CE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDKDNYKKFYE F+KNIKLGIHEDS NR K++E LR++S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD V +SAFVER+ KRGFEVL M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK E+ KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH IM++L+ + +ADKNDK+VKDLV+LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI+DDD+  +   +   P  + P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAIKHFSVEGQLEFRALLFIPRRAPFDLFENKKKKNNIKLYVRRVFIMDSCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFAELAEDKDNYKKFYESFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLSEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEEEKKKMEDDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAEADKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDIPSEEPTSAPAPEEIPPLEGDDDASRMEEVD 725          

HSP 2 Score: 352.058 bits (902), Expect = 1.159e-109
Identity = 178/213 (83.57%), Postives = 198/213 (92.96%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS KDL I IIP+K   TLT+VDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K DN EPIGRG+KVIL++KEDQ EY+++K++KE++KKHSQFIGYPI L +EKERDKEIS
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKLERTLTLVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVITKHNDDEQYAWESSAGGSFTVKVDNGEPIGRGTKVILHLKEDQTEYIEDKRVKEVVKKHSQFIGYPITLYVEKERDKEIS 225          
BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 667.537 bits (1721), Expect = 0.000e+0
Identity = 342/443 (77.20%), Postives = 399/443 (90.07%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIP-VGPTSTEDEAGKMEEVD 2335
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNC++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY++RMK+ QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH I+++L+ + +ADKNDKSVKDLV+LLFET+LLSSGF+L+DPQ H NRI+RMIKLGLGI++DD+  +   +  I  + P   +D+  +MEEVD
Sbjct:  289 LNKTKPLWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKDNYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIIETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLDDPQTHSNRIYRMIKLGLGIDEDDLSTEEPSSAPIEDMPPLEGDDDTSRMEEVD 731          

HSP 2 Score: 358.992 bits (920), Expect = 2.629e-112
Identity = 181/218 (83.03%), Postives = 203/218 (93.12%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            E D ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLT+PS LDS KDL I+IIP+K+  TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K DNSEP+ RG+KVIL++KEDQ EY++E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   11 EEDVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTEPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDNSEPVNRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLYVEKERDKEVS 228          
BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Match: hsp90aa1.2 (Astyanax mexicanus heat shock protein HSP 90-alpha 1-like (LOC103024454), mRNA. [Source:RefSeq mRNA;Acc:NM_001291257])

HSP 1 Score: 667.152 bits (1720), Expect = 0.000e+0
Identity = 342/443 (77.20%), Postives = 399/443 (90.07%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIP-VGPTSTEDEAGKMEEVD 2335
            LNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNC++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKKFYEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY++RMK+ QK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLKE++GK LV VTKEGLELPEDE+EKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH I+++L+ + +ADKNDKSVKDLV+LLFET+LLSSGF+L+DPQ H NRI+RMIKLGLGI++DD+  +   +  I  + P   +D+  +MEEVD
Sbjct:  288 LNKTKPLWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKDNYKKFYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDTQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKEFEGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIIETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLDDPQTHSNRIYRMIKLGLGIDEDDLSTEEPSSAPIEDMPPLEGDDDTSRMEEVD 730          

HSP 2 Score: 358.607 bits (919), Expect = 3.442e-112
Identity = 181/218 (83.03%), Postives = 204/218 (93.58%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            E +AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLT+PS LDS KDL I+IIP+K+  TLTI+DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY WESSAGGSFT+K DNSEP+ RG+KVIL++KEDQ EY++E++IKEI+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   10 EDEAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTEPSKLDSGKDLKIEIIPNKEERTLTIIDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYAWESSAGGSFTVKVDNSEPVNRGTKVILHLKEDQTEYIEERRIKEIVKKHSQFIGYPITLYVEKERDKEVS 227          
BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003399.1 (pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 gene:ENSPMAG00000002912.1 transcript:ENSPMAT00000003399.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 655.21 bits (1689), Expect = 0.000e+0
Identity = 340/442 (76.92%), Postives = 395/442 (89.37%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKP+WTRNPDD+SQE+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCEDLIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKC+ELF  + EDK+NYKKFYEQF+KN+KLGIHEDS NR +++E LR++++ +GE++ SLK+Y+SRMKENQK IYYITGESK+ V +SAFVER+ KRG EV+ M +PIDEY VQQLKE+DGK LV VTKEGLELPEDEDEKKK EE KA +E LCKV+K+ILDKKVEKVTVSNRLV+SPCCIVTS +GW+ANMERIMKAQALRDSSTMGYMAAKKHLEINP+H I+++L+ + +ADKNDKSVKDL++LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI+DD+   D +        P    ++A +MEEVD
Sbjct:  260 LNKTKPLWTRNPDDISQEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEDLIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCMELFTGLAEDKENYKKFYEQFSKNMKLGIHEDSQNRKRLSEMLRYHTSVTGEDVCSLKEYVSRMKENQKHIYYITGESKEQVSNSAFVERVRKRGLEVVYMTEPIDEYCVQQLKEFDGKTLVSVTKEGLELPEDEDEKKKQEEAKAKYENLCKVVKEILDKKVEKVTVSNRLVASPCCIVTSTYGWTANMERIMKAQALRDSSTMGYMAAKKHLEINPEHPIVETLRQKAEADKNDKSVKDLIILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDEPIPDESTPTVTEEMPPLEGEDASRMEEVD 701          

HSP 2 Score: 281.182 bits (718), Expect = 5.512e-84
Identity = 146/216 (67.59%), Postives = 173/216 (80.09%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS +DS K+L I +IP+++  T                            AFMEALQAGADISMIGQFGVGFYS+YL+A++V V++K NDDEQYLWESSAGGSFT++ DN E IGRG+K++L++KEDQ EYL+EK+IK+I+KKHSQFIGYPI L +EKERDKE+S
Sbjct:   13 ETETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKMDSGKELKIDVIPNRNERT----------------------------AFMEALQAGADISMIGQFGVGFYSAYLIAERVSVVTKHNDDEQYLWESSAGGSFTVRLDNGESIGRGTKIVLHLKEDQSEYLEEKRIKDIVKKHSQFIGYPITLFVEKERDKEVS 200          
BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Match: hsp90b1 (heat shock protein 90, beta (grp94), member 1 [Source:ZFIN;Acc:ZDB-GENE-031002-1])

HSP 1 Score: 338.961 bits (868), Expect = 8.529e-105
Identity = 184/416 (44.23%), Postives = 269/416 (64.66%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFE--NKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQ-LKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIE 2239
            +N  KPIW R   +V  ++Y  FYKS + D ++ L   HF+ EG++ FR++LF P  AP  +F+    KK + IK+YVRRVFI D+  D++P+YLNFVKGVVDS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++ ++I  D+   +KF+++F  NIKLG+ ED  NR ++A+ LRF S+   +++TSL++Y+ RMKE Q  IY+I G ++  V  S FVERL K+G+EVL + + +DEY +Q  L ++       +      L             +  F  LC        +++EK TVS RL+ SPC +V SQ+GWS NMERIMKAQA    +D+++  Y + KK  EINP H ++K L  RV A + D + KDL ++LFET+ L SG+ L+D +   +RI RM+++ L I+
Sbjct:  313 MNDIKPIWQRVTKEVEDDEYKAFYKSFSKDSDEPLTWIHFTAEGEVTFRSILFVPTSAPRGMFDEYGTKKTDFIKMYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIKKKLVRKTLDMIKKIA-DESYQEKFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSYGTDKLTSLEEYVERMKEKQDKIYFIAGANRKEVESSPFVERLLKKGYEVLFLTEAVDEYCIQSDLGQFMDLYASILITAWSRLGPSLRVYAARFAVQRGFPLLCT-------RQIEKATVSQRLLGSPCALVASQYGWSGNMERIMKAQAYQTGKDAASNFYGSQKKTFEINPRHPLIKELLTRVQASEEDATAKDLALVLFETATLRSGYLLQDTRSFSDRIERMLRVSLNID 720          

HSP 2 Score: 155.221 bits (391), Expect = 1.865e-39
Identity = 93/203 (45.81%), Postives = 129/203 (63.55%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYD-NSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPI 811
            AE   FQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR  SLTD   LD+  +L IKI  DK+   L I      +++A     L T  +S ++             +IGQFGVGFYS++LVAD++ V SK N+D Q++WES +   FT+  D     + RG+ + L +KE+  +YL+ + IK ++KK+SQFI +PI
Sbjct:   75 AEKHVFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLMSLTDGKALDATDELTIKIKADKEKNLLHIF-----LSRA---QELATEGQSTSE-------------LIGQFGVGFYSAFLVADRIVVTSKHNNDTQHIWESDS-SEFTVTEDPRGNTLARGTTITLVLKEEAADYLELETIKNLVKKYSQFINFPI 255          
BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Match: hsp90ab1 (heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-031001-3])

HSP 1 Score: 303.908 bits (777), Expect = 1.228e-97
Identity = 198/317 (62.46%), Postives = 240/317 (75.71%), Query Frame = 2
Query:  311 SSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDN-SEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKER------DKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVR 1240
            S+ ALDKIRY+SLTDPS LD+ K+L I IIP+K   TLT                           FMEALQAGADISMIGQFGVGFYS+YLVA++V V++K NDDEQY+WESSAGGSFT++ DN  EP+GRG+K++L++KEDQ EYL+E+ IK+I+KKHSQFIGYPI L +EKER      D+E  ++ A    K+E+  +DT +   +   ++E+     DK KKKKKIKEKY D+EELNKTKP+WTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKK+NNIKLYVR
Sbjct:    1 SAQALDKIRYESLTDPSKLDTGKELKIDIIPNKIDRTLT---------------------------FMEALQAGADISMIGQFGVGFYSAYLVAERVTVVTKHNDDEQYVWESSAGGSFTVRPDNDGEPLGRGTKIVLHIKEDQTEYLEERSIKDIVKKHSQFIGYPITLYVEKERNKEVSDDEEDKEEAAPDKPKEERSDDDTPNIEDVGSDEEEDKAKDSDKKKKKKKIKEKYTDKEELNKTKPLWTRNPDDITAEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKKNNIKLYVR 290          
BLAST of Heat shock protein 90 vs. Ensembl Yeast
Match: HSC82 (Cytoplasmic chaperone of the Hsp90 family; plays a role in determining prion variants; redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock; contains two acid-rich unstructured regions that promote the solubility of chaperone-substrate complexes; HSC82 has a paralog, HSP82, that arose from the whole genome duplication [Source:SGD;Acc:S000004798])

HSP 1 Score: 519.62 bits (1337), Expect = 2.734e-175
Identity = 278/446 (62.33%), Postives = 341/446 (76.46%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVD-ADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG-DIPVG--PTSTEDEAGKMEEVD 2335
            LNKTKP+WTRNP D++QE+Y  FYKS++NDWED L VKHFSVEGQLEFRA+LF PKRAPFDLFE+KKK+NNIKLYVRRVFI D  EDLIPE+L+FVKGVVDSEDLPLN+SREMLQQNKI+KVIRKN+VKK +E F EI ED + + KFY  FAKNIKLG+HED+ NR  +A+ LR+ ST S +E+TSL DY++RM E+QK+IYYITGES   V  S F++ L  + FEVL + DPIDEY+  QLKE++GK LV +T +  EL E ++EK + E++   +EPL K +KDIL  +VEKV VS +L+ +P  I T QFGWSANMERIMKAQALRDSS   YM++KK  EI+P   I+K LK RVD     DK+VKDL  LLFET+LL+SGFSLE+P    +RI+R+I LGL I++D+    A EA  + PV   P  TE     MEEVD
Sbjct:  266 LNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFDKFYSAFAKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDIT-KDFELEETDEEKAEREKEIKEYEPLTKALKDILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTNLLFETALLTSGFSLEEPTSFASRINRLISLGLNIDEDEETETAPEASTEAPVEEVPADTE-----MEEVD 705          

HSP 2 Score: 297.745 bits (761), Expect = 2.603e-90
Identity = 149/215 (69.30%), Postives = 186/215 (86.51%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDN-SEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
             ETF FQAEI QLMSLIINT YSNKEIFLRELISN+SDALDKIRY++L+DP  L++  DL I+I P  +   L I D+GIGMTKA+LINNLGTIA+SGTKAFMEAL AGAD+SMIGQFGVGFYS +LVAD+VQVISK+N+DEQY+WES+AGGSFT+  D  +E IGRG+ + L++K+DQ+EYL+EK+IKE+IK+HS+F+ YPI+L++ KE +KE+
Sbjct:    3 GETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYQALSDPKQLETEPDLFIRITPKPEEKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKNNEDEQYIWESNAGGSFTVTLDEVNERIGRGTVLRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLLVTKEVEKEV 217          
BLAST of Heat shock protein 90 vs. Ensembl Yeast
Match: HSP82 (Hsp90 chaperone; redundant in function with Hsc82p; required for pheromone signaling, negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding, nucleotide addition; protein abundance increases in response to DNA replication stress; contains two acid-rich unstructured regions that promote solubility of chaperone-substrate complexes; HSP82 has a paralog, HSC82, that arose from the whole genome duplication [Source:SGD;Acc:S000006161])

HSP 1 Score: 513.457 bits (1321), Expect = 6.706e-173
Identity = 273/446 (61.21%), Postives = 342/446 (76.68%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVD-ADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI-EDDDVEI--DATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKP+WTRNP D++QE+Y  FYKS++NDWED L VKHFSVEGQLEFRA+LF PKRAPFDLFE+KKK+NNIKLYVRRVFI D  EDLIPE+L+FVKGVVDSEDLPLN+SREMLQQNKI+KVIRKN+VKK +E F EI ED + ++KFY  F+KNIKLG+HED+ NR  +A+ LR+ ST S +E+TSL DY++RM E+QK+IYYITGES   V  S F++ L  + FEVL + DPIDEY+  QLKE++GK LV +T +  EL E ++EK + E++   +EPL K +K+IL  +VEKV VS +L+ +P  I T QFGWSANMERIMKAQALRDSS   YM++KK  EI+P   I+K LK RVD     DK+VKDL  LL+ET+LL+SGFSL++P    +RI+R+I LGL I ED++ E   +A+ A  +   P  TE     MEEVD
Sbjct:  270 LNKTKPLWTRNPSDITQEEYNAFYKSISNDWEDPLYVKHFSVEGQLEFRAILFIPKRAPFDLFESKKKKNNIKLYVRRVFITDEAEDLIPEWLSFVKGVVDSEDLPLNLSREMLQQNKIMKVIRKNIVKKLIEAFNEIAEDSEQFEKFYSAFSKNIKLGVHEDTQNRAALAKLLRYNSTKSVDELTSLTDYVTRMPEHQKNIYYITGESLKAVEKSPFLDALKAKNFEVLFLTDPIDEYAFTQLKEFEGKTLVDIT-KDFELEETDEEKAEREKEIKEYEPLTKALKEILGDQVEKVVVSYKLLDAPAAIRTGQFGWSANMERIMKAQALRDSSMSSYMSSKKTFEISPKSPIIKELKKRVDEGGAQDKTVKDLTKLLYETALLTSGFSLDEPTSFASRINRLISLGLNIDEDEETETAPEASTAAPVEEVPADTE-----MEEVD 709          

HSP 2 Score: 304.294 bits (778), Expect = 1.084e-92
Identity = 154/215 (71.63%), Postives = 187/215 (86.98%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDN-SEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            +ETF FQAEI QLMSLIINT YSNKEIFLRELISN+SDALDKIRYKSL+DP  L++  DL I+I P  +   L I D+GIGMTKA+LINNLGTIA+SGTKAFMEAL AGAD+SMIGQFGVGFYS +LVAD+VQVISKSNDDEQY+WES+AGGSFT+  D  +E IGRG+ + L++K+DQ+EYL+EK+IKE+IK+HS+F+ YPI+LV+ KE +KE+
Sbjct:    3 SETFEFQAEITQLMSLIINTVYSNKEIFLRELISNASDALDKIRYKSLSDPKQLETEPDLFIRITPKPEQKVLEIRDSGIGMTKAELINNLGTIAKSGTKAFMEALSAGADVSMIGQFGVGFYSLFLVADRVQVISKSNDDEQYIWESNAGGSFTVTLDEVNERIGRGTILRLFLKDDQLEYLEEKRIKEVIKRHSEFVAYPIQLVVTKEVEKEV 217          
BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Match: HSP90 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ66])

HSP 1 Score: 989.564 bits (2557), Expect = 0.000e+0
Identity = 547/713 (76.72%), Postives = 632/713 (88.64%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI-EDDDVE-IDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            D ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY SLTDPSVLDS KDL I +IP+K+  +LTI D+G+GMTKADL+NNLGTIA+SGTK FMEALQAGADISMIGQFGVGFYS+YLVA+KV V +K NDDEQY+WES+AGGSFT+K D+ EP+GRG+K++LY+KEDQ EYL+EK+IKEI+KKHSQFIGYP+ L+++KERDKE+SDDE E ++KK++E E+ +       ++D ++D+ K   KKKK IKEKY + EELNKTKPIW RN D+++ E+Y EFYKSLTNDWE+HLAVKHFSVEGQLEFRALLF PKRAPFDLFE++KKRNNIKLYVRRVFIMDNCEDLIPEYL F+KGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKC+ELF EI ED+DNYKKFYEQF KN+KLGIHEDSVNR K+A+ LR++S+SSG+E+TSLKDY++RMKENQKDIY+ITGESKD V HSAFVER+  RGFEVL MV+PIDEY++QQLKEYDGKKLV VTKEGLELPEDEDEKK  EE+ A +E LCKV+KDILDKK+EKV VS+RLVSSPCCIVTSQFGW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH+IM SL+ +V+ADKNDKS+KDLVMLL+ETSLL+SGF+LEDPQVH  RI+RMI LGLGI E+ + E  DA      P+      D+A KMEEVD
Sbjct:   15 DVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYLSLTDPSVLDSCKDLKITLIPNKEENSLTIQDSGVGMTKADLVNNLGTIAKSGTKTFMEALQAGADISMIGQFGVGFYSAYLVAEKVVVTTKHNDDEQYIWESAAGGSFTVKRDSGEPLGRGTKIVLYLKEDQTEYLEEKRIKEIVKKHSQFIGYPLSLLVQKERDKEVSDDEEEEEEKKDEEEEEEDGDKDKPKIEDMDEDEDKKDKKKKKTIKEKYTEMEELNKTKPIWMRNADEITTEEYGEFYKSLTNDWEEHLAVKHFSVEGQLEFRALLFVPKRAPFDLFESRKKRNNIKLYVRRVFIMDNCEDLIPEYLGFIKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCMELFNEIAEDQDNYKKFYEQFGKNLKLGIHEDSVNRAKLADLLRYHSSSSGDELTSLKDYVTRMKENQKDIYFITGESKDQVSHSAFVERVKSRGFEVLYMVEPIDEYAIQQLKEYDGKKLVSVTKEGLELPEDEDEKKAREEKVAKYEGLCKVIKDILDKKIEKVVVSSRLVSSPCCIVTSQFGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHAIMDSLRKKVEADKNDKSLKDLVMLLYETSLLTSGFTLEDPQVHSGRIYRMIGLGLGIDEEPEAEGADAVTEDMPPLEGDDANDDASKMEEVD 727          
BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Match: EDO45344 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RT97])

HSP 1 Score: 362.459 bits (929), Expect = 7.344e-113
Identity = 205/416 (49.28%), Postives = 296/416 (71.15%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFEN-KKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXX-XXXXXXXXXXXXXXXXXXXXLCKVMK-DILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQAL---RDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIE 2239
            LN  KPIWTR P ++  ++Y EFYKS T + ED LA  HF  EG++ FR++LF PK AP +LF +  KK + IKL+VRRVFI DN E+++P+YL+F++GVVDS+DLPLN+SRE LQQ+K+LKVI+K LV+K L++ ++I ++ D    F+++++ NIKLG+ ED  NR ++A+ LRFYS++S ++MTSL +YI RMKE Q  IY++ G ++  V  S FVE+L K G+EVL +++P+DEY +Q L E++GKK   V KEGL+   + + +KKKFEE +  +EPL K +K D L  ++EK T+S RL  SPC +V S +GWS NMERIM++QA     D S   Y   KK LE+NP H ++K L  RV+ +K+D++ KDL  +LFET+ L SG+ ++D      RI RM++L +G++
Sbjct:  353 LNTNKPIWTRKPKEIKDDEYNEFYKSFTKESEDPLAKIHFVAEGEVTFRSILFVPKAAPSNLFSDYGKKMDAIKLFVRRVFITDNFEEMMPKYLSFIRGVVDSDDLPLNVSREQLQQHKLLKVIKKKLVRKALDMIKKIPKE-DYMATFWKEYSTNIKLGVIEDHSNRTRLAKLLRFYSSNSEKDMTSLAEYIERMKEKQDVIYFMAGHNRKEVESSPFVEKLLKEGYEVLYLIEPVDEYCMQSLPEFEGKKFQNVAKEGLKIGEDSDKKKKKFEELEKTYEPLLKWLKEDALKDQIEKATISERLHDSPCALVASSYGWSGNMERIMRSQAYAKSSDPSNEYYATQKKTLEVNPRHPLVKQLLKRVEENKDDQTAKDLSRILFETATLRSGYLVKDSADFAGRIERMLRLSMGVD 767          

HSP 2 Score: 216.853 bits (551), Expect = 1.208e-59
Identity = 120/213 (56.34%), Postives = 153/213 (71.83%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGAD----ISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEP-IGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEK 829
            AE   FQAE+ ++M LIIN+ Y NKEIFLRELISNSSDALDKIR  SLTD +  DS  +L IKI  DK+   L + DTGIGMTK +LI NLGTIA+SGT  F + +Q  A       +IGQFGVGFYSS+LVAD+V V SK+NDD+QY+WES A  SF+I  D   P + RG+ + L++KE+  +YL+ + IK+++KK+SQFI +PI L   K
Sbjct:   76 AEKHEFQAEVNRMMKLIINSLYRNKEIFLRELISNSSDALDKIRLMSLTDKTAFDSGDELSIKIKADKENNILHVTDTGIGMTKEELIKNLGTIAKSGTSEFFQKIQEAASSDSASDLIGQFGVGFYSSFLVADRVIVTSKNNDDKQYIWESDA-SSFSISEDPRGPTLKRGTTISLHLKEEARDYLEPETIKDLVKKYSQFINFPIFLWTSK 287          
BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Match: EDO45666 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RS03])

HSP 1 Score: 174.866 bits (442), Expect = 3.910e-46
Identity = 91/204 (44.61%), Postives = 142/204 (69.61%), Query Frame = 2
Query:  221 FQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADIS---MIGQFGVGFYSSYLVADKVQVISKS--NDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            FQAE  QL+ ++  + YS KE+F+RE+ISN+SDAL+K+R+  LT   V ++   L I I  D++AGT TI D G+GMT+ +L+++LG IA+SG+K FME L+  A  S   +IGQFGVGFYS+++VADKV V +KS   + + Y W S   GS+  +Y  +  + RG+K++L++KED   +  +  +++I++++S F+G+PI L
Sbjct:   15 FQAETKQLLDIVAKSLYSEKEVFIREVISNASDALEKVRHFFLTGKDVSETETSLEIMIETDQEAGTFTIQDNGVGMTEEELMDHLGVIAKSGSKVFMEKLKNEARSSHENIIGQFGVGFYSTFMVADKVDVYTKSYQPNSQGYFWTSDGSGSY--EYAEANGVARGTKLVLHLKEDCKRFAMKTAVEDIVQRYSNFVGFPIYL 216          

HSP 2 Score: 167.933 bits (424), Expect = 6.639e-44
Identity = 108/367 (29.43%), Postives = 193/367 (52.59%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELF-EEIMEDKDNYKKFYEQFAKNIKLGI--HEDSVNRNKIAEFLRFYSTSSGE-EMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTX--XXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDK-KVEKVTVSNRLVSS--PCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLK 2083
            +N  +P+WT  P D+S+E + EFY+ L+  ++      H+  +  L  R++ + P+  P  +F  ++  + I LY RRV I    E ++P +L F++GVVDSED+PLN+SRE+LQ + ++K +   L  + ++   E+  +D+  Y+KF++     I+ G+   ED   + +IA+ L F S++     +T+L  Y+SRMK  QK +YY+   S+D    S + E L +   EVL   +  D+  +  L++Y+ K ++         E  + ++E +  +      + L   M  IL   +V  V VS RL ++  P  I       + +  +++K +  ++   M Y   +  LEINP H ++K L+
Sbjct:  221 INTIQPLWTLEPRDISKEQHDEFYQFLSKGYDKPRYYLHYKTDAPLNIRSIFYFPETLP-QMFNMQQMESGISLYSRRVLIQAKAEKVLPRWLRFIRGVVDSEDIPLNLSRELLQDSALIKKLSNVLSARLVKFLQEQARKDRVKYEKFFKDCGIFIREGVVTTEDEEQKEEIAKLLLFESSNEKPGTLTNLPAYVSRMKPTQKKVYYLCAPSRDLAETSPYYETLKQNDVEVLFSYNEQDDVVLHYLRKYENKAVISAENFLSEAEDTKPKNEPEVEDVTPEEGKDLAGWMSSILGPTRVVGVKVSKRLANTNHPAMITVPDMVAAKHWLKLIKTEHNKEVENMKYQIIQPTLEINPKHDLIKRLE 586          
BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 989.949 bits (2558), Expect = 0.000e+0
Identity = 558/712 (78.37%), Postives = 641/712 (90.03%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAG-DIPVGPTSTEDEAGKMEEVD 2335
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS KDL I IIP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY WESSAGGSFT+K D+ EPIGRG+K+IL++KEDQ EY++EK++KEI+KKHSQFIGYPI L +EKERDKEISDDEAE + ++++  E+ EDKPKIED+  ++++D KDK KKKKKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNIKLGIHEDS NR K++E LR++S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD V +SAFVER+ KRGFEVL M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK E+ KA FE LCK+MK+ILDKKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH IM++L+ + + DKNDK+VKDLV+LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI+DDD+   E  +T A  ++P      +D++ +MEEVD
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKADRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVVVITKHNDDEQYAWESSAGGSFTVKVDSGEPIGRGTKIILHLKEDQTEYIEEKRVKEIVKKHSQFIGYPITLFVEKERDKEISDDEAEEEKEEKETKEEGEDKPKIEDVGSDDEEDAKDKGKKKKKIKEKYIDQEELNKTKPIWTRNPDDITSEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFGELAEDKENYKKFYEGFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGLELPEDEEEKKKMEDDKAKFENLCKLMKEILDKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAETDKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDIPTEEPASTSAPEEMPPLEGDADDDSSRMEEVD 724          
BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90ab1 (heat shock protein 90 alpha family class B member 1 [Source:NCBI gene;Acc:100125466])

HSP 1 Score: 960.288 bits (2481), Expect = 0.000e+0
Identity = 546/712 (76.69%), Postives = 627/712 (88.06%), Query Frame = 2
Query:  212 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDV---EIDATEAG-DIPVGPTSTEDEAGKMEEVD 2335
            TFAFQAEIAQLMSLIINTFYSNKEIFLRELISN+SDALDKIRY+SLTDPS LDS KDL I IIP+K   TLTIVDTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA++V VI+K NDDEQY WESSAGGSFT+K D+ EPIGRG+K+IL++KEDQ EY++EK++KEI+KKHSQFIGYPI L +EKERDKEISDDEAE + ++++  E+ EDKPKIED+  ++++D KDK KKKKKIKEKYID+EELNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RAPFDLFENKKK+NNIKLYVRRVFIMDNCE+LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKN+VKKCLELF E+ EDK+NYKKFYE F+KNIKLGIHEDS NR K++E LR++S+ SG+EMTSL +Y+SRMKENQK IYYITGESKD V +SAFVER+ KRGFEVL M +PIDEY VQQLKE+DGK LV VTKEGLELPEDE+EKKK E+                 KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYM AKKHLEINPDH IM++L+ + + DKNDK+VKDLV+LLFET+LLSSGFSL+DPQ H NRI+RMIKLGLGI+DDD+   E  +T A  ++P      +D++ +MEEVD
Sbjct:   13 TFAFQAEIAQLMSLIINTFYSNKEIFLRELISNASDALDKIRYESLTDPSKLDSGKDLKIDIIPNKADRTLTIVDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAERVVVITKHNDDEQYAWESSAGGSFTVKVDSGEPIGRGTKIILHLKEDQTEYIEEKRVKEIVKKHSQFIGYPITLFVEKERDKEISDDEAEEEKEEKETKEEGEDKPKIEDVGSDDEEDAKDKGKKKKKIKEKYIDQEELNKTKPIWTRNPDDITSEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAPFDLFENKKKKNNIKLYVRRVFIMDNCEELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFGELAEDKENYKKFYEGFSKNIKLGIHEDSQNRKKLSELLRYHSSQSGDEMTSLTEYLSRMKENQKSIYYITGESKDQVANSAFVERVRKRGFEVLYMTEPIDEYCVQQLKEFDGKNLVSVTKEGLELPEDEEEKKKMEDD----------------KKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMMAKKHLEINPDHPIMETLRQKAETDKNDKAVKDLVILLFETALLSSGFSLDDPQTHSNRIYRMIKLGLGIDDDDIPTEEPASTSAPEEMPPLEGDADDDSSRMEEVD 708          
BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 695.271 bits (1793), Expect = 0.000e+0
Identity = 350/445 (78.65%), Postives = 401/445 (90.11%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNC++LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK YEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY+SRMK+NQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLK++DGK LV VTKEGLELPEDE+EKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH IM++L+ + +ADKNDKSVKDLV+LLFET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD  ++ T +    D+P  P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVSRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDEDDTPVEETTSAPTEDMP--PLEGDDDASRMEEVD 724          

HSP 2 Score: 347.051 bits (889), Expect = 9.080e-108
Identity = 177/217 (81.57%), Postives = 198/217 (91.24%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I++ PD  A TLTI DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+K DN EPIGRG+KVIL++KEDQ EY +EK+IKE+IKKHSQFIGYPI L +EK R+KE+
Sbjct:   10 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEV 226          
BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 694.501 bits (1791), Expect = 0.000e+0
Identity = 349/445 (78.43%), Postives = 401/445 (90.11%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNC++LIPEYLNF+KGVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK YEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY++RMK+NQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLK++DGK LV VTKEGLELPEDE+EKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH IM++L+ + +ADKNDKSVKDLV+LLFET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD  ++ T +    D+P  P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIKGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDEDDTPVEETTSAPTEDMP--PLEGDDDASRMEEVD 724          

HSP 2 Score: 347.051 bits (889), Expect = 7.675e-108
Identity = 177/217 (81.57%), Postives = 198/217 (91.24%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I++ PD  A TLTI DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+K DN EPIGRG+KVIL++KEDQ EY +EK+IKE+IKKHSQFIGYPI L +EK R+KE+
Sbjct:   10 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEV 226          
BLAST of Heat shock protein 90 vs. Ensembl Medaka
Match: hsp90aa1.2 (heat shock protein HSP 90-alpha [Source:NCBI gene;Acc:101169506])

HSP 1 Score: 693.345 bits (1788), Expect = 0.000e+0
Identity = 348/445 (78.20%), Postives = 401/445 (90.11%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAG---DIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD++ E+Y EFYKSLTNDWEDHLAVKHFSVEGQLEFRALLF P+RA FDLFENKKKRNNIKLYVRRVFIMDNC++LIPEYLNF++GVVDSEDLPLNISREMLQQ+KILKVIRKNLVKKCLELF E+ EDKDNYKK YEQF+KNIKLGIHEDS NR K++E LR+Y+++SG+EM SLKDY++RMK+NQK IYYITGE+KD V +SAFVERL K G EV+ M++PIDEY VQQLK++DGK LV VTKEGLELPEDE+EKKK EE+KA FE LCK+MKDIL+KKVEKVTVSNRLVSSPCCIVTS +GW+ANMERIMKAQALRD+STMGYMAAKKHLEINPDH IM++L+ + +ADKNDKSVKDLV+LLFET+LLSSGF+LEDPQ H NRI+RMIKLGLGI++DD  ++ T +    D+P  P   +D+A +MEEVD
Sbjct:  282 LNKTKPIWTRNPDDITNEEYGEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFVPRRAAFDLFENKKKRNNIKLYVRRVFIMDNCDELIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELSEDKDNYKKLYEQFSKNIKLGIHEDSQNRKKLSELLRYYTSASGDEMVSLKDYVTRMKDNQKHIYYITGETKDQVANSAFVERLRKAGLEVIYMIEPIDEYCVQQLKDFDGKNLVSVTKEGLELPEDEEEKKKQEEKKAQFENLCKIMKDILEKKVEKVTVSNRLVSSPCCIVTSTYGWTANMERIMKAQALRDNSTMGYMAAKKHLEINPDHPIMETLRQKAEADKNDKSVKDLVILLFETALLSSGFTLEDPQTHANRIYRMIKLGLGIDEDDTPVEETTSAPTEDMP--PLEGDDDASRMEEVD 724          

HSP 2 Score: 347.051 bits (889), Expect = 9.272e-108
Identity = 177/217 (81.57%), Postives = 198/217 (91.24%), Query Frame = 2
Query:  197 ETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEI 847
            E + ETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY+SLTDPS LDS K+L I++ PD  A TLTI DTGIGMTKADLINNLGTIA+SGTKAFMEALQAGADISMIGQFGVGFYS+YLVA+KV VI+K NDDEQY+WES+AGGSFT+K DN EPIGRG+KVIL++KEDQ EY +EK+IKE+IKKHSQFIGYPI L +EK R+KE+
Sbjct:   10 EEEVETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYESLTDPSKLDSCKELKIEVRPDLHARTLTINDTGIGMTKADLINNLGTIAKSGTKAFMEALQAGADISMIGQFGVGFYSAYLVAEKVTVITKHNDDEQYIWESAAGGSFTVKPDNGEPIGRGTKVILHLKEDQTEYCEEKRIKEVIKKHSQFIGYPITLYVEKTREKEV 226          
BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000071533.1 (SMESG000071533.1)

HSP 1 Score: 1253.04 bits (3241), Expect = 0.000e+0
Identity = 714/715 (99.86%), Postives = 715/715 (100.00%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTI+DTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEISDDEAEVDDKKEKESEDTEDKPKIEDLDDEEDDDKKDKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD
Sbjct:    1 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIIDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEISDDEAEVDDKKEKESEDTEDKPKIEDLDDEEDDDKKDKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 715          
BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000024822.1 (SMESG000024822.1)

HSP 1 Score: 1171.38 bits (3029), Expect = 0.000e+0
Identity = 633/714 (88.66%), Postives = 678/714 (94.96%), Query Frame = 2
Query:  194 SETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEISXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXLNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            S  D+ETFAFQAEIAQL+SLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLD+AK+L+IKIIPDKDAGTLTI+DTGIGMTK+DLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISK NDDEQYLWESSAGGSFTIK D SEP+GRGSK+IL+MKEDQ+EYL+E+KIKEIIKKHSQFIGYPIKLVL  E++++    + E + + +KE  +  +     +  D+E+DD K   KKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKN+KLGIHEDSVNRNK+A+FLR++STSSGEEMTSLKDY+SRMKENQKDIYYITGESKDNV HSAFVERLTKRGFEVL M+DPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDE+EKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHS+MK+LK RVDADKNDKSVKDLVMLL+ETSLLSSGF+LEDPQ+H NRIHRMIKLGLGI++DD+EID TE GD+PVGP++TEDEAGKMEEVD
Sbjct:    3 SMNDSETFAFQAEIAQLLSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDTAKELIIKIIPDKDAGTLTIIDTGIGMTKSDLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKGNDDEQYLWESSAGGSFTIKPDTSEPLGRGSKIILFMKEDQVEYLEERKIKEIIKKHSQFIGYPIKLVL--EKERDKEVSDDEAETETKKEESEEGEDKPKIEDLDDEEDDDKKDKKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNLKLGIHEDSVNRNKLADFLRYHSTSSGEEMTSLKDYLSRMKENQKDIYYITGESKDNVAHSAFVERLTKRGFEVLYMIDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEEEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSVMKALKTRVDADKNDKSVKDLVMLLYETSLLSSGFALEDPQIHANRIHRMIKLGLGIDEDDMEIDTTEVGDVPVGPSATEDEAGKMEEVD 714          
BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000071531.1 (SMESG000071531.1)

HSP 1 Score: 826.624 bits (2134), Expect = 0.000e+0
Identity = 428/430 (99.53%), Postives = 430/430 (100.00%), Query Frame = 2
Query: 1046 DDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            +DVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYI+RMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD
Sbjct:  267 NDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYITRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKAAFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 696          

HSP 2 Score: 420.624 bits (1080), Expect = 1.875e-136
Identity = 219/220 (99.55%), Postives = 220/220 (100.00%), Query Frame = 2
Query:  191 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERDKEIS 850
            MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTI+DTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEIS
Sbjct:    1 MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIIDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERDKEIS 220          
BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000025598.1 (SMESG000025598.1)

HSP 1 Score: 742.265 bits (1915), Expect = 0.000e+0
Identity = 380/442 (85.97%), Postives = 414/442 (93.67%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVGPTSTEDEAGKMEEVD 2335
            LNKTKPIWTRNPDD+SQEDY+EFYKSL+NDWEDHLAVKHF+VEGQLEF+A+LFCPKRA FD+FENKKKRNNIKLYVRRVFIMDNCEDLIPEYL+F+KGVVDSEDLPLNISREMLQQNKILKV+RKN+VKKC+ELF+EIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNK+AEFLR+ STSSGEEM SLKDY+SRMKENQKDIYYITGE+K+ V  SAFVERL+KRGFEVL MVDPIDEYSVQQLKE+DGKKLVCVTKEGLELPEDE+EKKKFEEQKA FE LCKVMKD+LDKKVEKVTVSNRLV SPCC+VTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLK RVD DKNDK+VKDL+ LLFETSLL+SGFSLE+PQVHGNRIHRMIKLGLGI D++  ++        + P++ EDE  KMEEVD
Sbjct:  268 LNKTKPIWTRNPDDISQEDYSEFYKSLSNDWEDHLAVKHFAVEGQLEFKAILFCPKRASFDMFENKKKRNNIKLYVRRVFIMDNCEDLIPEYLSFIKGVVDSEDLPLNISREMLQQNKILKVVRKNIVKKCIELFDEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKLAEFLRYNSTSSGEEMISLKDYVSRMKENQKDIYYITGENKETVAKSAFVERLSKRGFEVLFMVDPIDEYSVQQLKEFDGKKLVCVTKEGLELPEDEEEKKKFEEQKAEFESLCKVMKDVLDKKVEKVTVSNRLVDSPCCVVTSQFGWSANMERIMKAQALRDSSTMGYMAAKKHLEINPDHSIMKSLKKRVDTDKNDKAVKDLINLLFETSLLTSGFSLEEPQVHGNRIHRMIKLGLGI-DEEESVEEITEAVADLAPSAVEDEE-KMEEVD 707          

HSP 2 Score: 373.629 bits (958), Expect = 3.581e-118
Identity = 187/212 (88.21%), Postives = 208/212 (98.11%), Query Frame = 2
Query:  203 DAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKLVLEKERD 838
            +AETFAFQAEI+QLMSLIINTFYSNKEIFLRELISN+SDALDK+RYKSLTDPSVLDS K+LMIK+IPDKD+ TLT+ DTG+GMTKA+LINNLGTIARSGTKAFMEAL AGADISMIGQFGVGFYS+YLVAD+VQVI+KSN+DEQY+WESSAGGSFTIK+D+SEPIGRG+K+IL+MKEDQ+EYLDEKKIKEIIKKHSQFIGYPIKLVLEKERD
Sbjct:    6 EAETFAFQAEISQLMSLIINTFYSNKEIFLRELISNASDALDKVRYKSLTDPSVLDSQKELMIKVIPDKDSNTLTLYDTGVGMTKAELINNLGTIARSGTKAFMEALTAGADISMIGQFGVGFYSAYLVADRVQVITKSNEDEQYMWESSAGGSFTIKHDDSEPIGRGTKIILHMKEDQVEYLDEKKIKEIIKKHSQFIGYPIKLVLEKERD 217          
BLAST of Heat shock protein 90 vs. Planmine SMEST
Match: SMESG000041107.1 (SMESG000041107.1)

HSP 1 Score: 366.311 bits (939), Expect = 1.761e-114
Identity = 203/459 (44.23%), Postives = 318/459 (69.28%), Query Frame = 2
Query: 1010 LNKTKPIWTRNPDDVSQEDYAEFYKSLTNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKK-KRNNIKLYVRRVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNLVKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFYSTSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGFEVLLMVDPIDEYSVQQLKEYDGKKLVCVTXXXXXXXXXXXXXXXXXXXXXXXXXLCKVMKD-ILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKAQALRDSSTM--GYMAA-KKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLLFETSLLSSGFSLEDPQVHGNRIHRMIKLGLGI-EDDDVEID-------ATEAGDIPVGPTSTED-----EAGKMEEV 2332
            +NK KPIWTR   D+  E+Y EFYKS     E+ LA  HF+ EG++ F+++LF P + P++ ++N +  R+NIK+YVRRVFI D+  D++P+YL+F+ G+VDS+DLPLN+SRE LQQNK+LKVI+K LV+K L++ +++ E+  ++ KF+++F+ ++KLG+ ED  NR ++A+ LRF+++ + ++ ++L DY+SRMKE Q+ IYYI G SKD++I S  VE++ K+GFEV+ M+DP+DEY VQ L E++GKK+  + KEG++  + +  K++ E     FEPL K +KD +L++++EK  +S RL +SPC +V S +GW+ NMERIMKAQA + +S     Y ++ KK LEINP H ++K LK +V+ +  D+  KD+ + L+ET++L SG+SL       +RI ++++  L I  D+ VE D       A + G++   P + ED     E+ K EE+
Sbjct:  339 VNKNKPIWTRKASDIKDEEYNEFYKSFGKTSENPLAKIHFTAEGEVTFKSILFVPAKPPYNYYQNPETHRDNIKMYVRRVFITDDFNDMMPKYLSFIVGIVDSDDLPLNVSRETLQQNKLLKVIKKKLVRKTLDMLKKMSEE--DFDKFWKEFSTSLKLGVVEDVSNRTRLAKLLRFWTSHNDKKQSTLTDYVSRMKEKQEVIYYIAGHSKDDLIKSPLVEKVLKKGFEVVYMIDPVDEYVVQSLTEFEGKKMQNLGKEGVKFDDSDKAKEQREITAKEFEPLLKWLKDSVLNEQIEKAEISERLSTSPCAVVASTYGWTGNMERIMKAQAYQSASNSYNEYQSSQKKILEINPKHPLIKELKRQVEKNPTDEKAKDIALTLYETAILRSGYSLPASGGFADRIEKILRSSLNIPHDEPVEDDEPVEEKPAEDEGEVTEPPKAAEDTAENKESAKKEEL 795          

HSP 2 Score: 232.261 bits (591), Expect = 6.743e-65
Identity = 120/208 (57.69%), Postives = 154/208 (74.04%), Query Frame = 2
Query:  206 AETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRYKSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIARSGTKAFMEALQAGADIS----MIGQFGVGFYSSYLVADKVQVISKSNDDEQYLWESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDXXXXXXXXXXHSQFIGYPIKL 817
            AE FAFQAE+ ++M LIIN+ Y NKEIFLRELISN+SDALDKIR+ SLTD + LD+ KDL IKI  DKD  +L IVDTG+GMTK DLI NLGTIA+SGT  F++ L      +    +IGQFGVGFYSS+LVADKV VISK NDD+Q++WES A     ++      + RG+++IL++KE+  EYL+   +K ++ K+SQFI +PI L
Sbjct:   81 AEKFAFQAEVDKMMKLIINSLYKNKEIFLRELISNASDALDKIRFISLTDSTALDAFKDLHIKIKADKDGKSLHIVDTGVGMTKQDLITNLGTIAKSGTSDFLKKLSDSKSTNEMSDLIGQFGVGFYSSFLVADKVTVISKHNDDKQHIWESDANSFSVVEDPRGNTLLRGTEIILHLKEEAHEYLEADSLKNLVTKYSQFINFPIYL 288          
The following BLAST results are available for this feature:
BLAST of Heat shock protein 90 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
HSP90AA14.516e-11177.75heat shock protein 90 alpha family class A member ... [more]
HSP90AA12.364e-10977.75heat shock protein 90 alpha family class A member ... [more]
HSP90AB13.935e-10876.85heat shock protein 90 alpha family class B member ... [more]
HSP90AB13.935e-10876.85heat shock protein 90 alpha family class B member ... [more]
HSP90AB13.935e-10876.85heat shock protein 90 alpha family class B member ... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp-902.191e-9678.13Heat shock protein 90 [Source:UniProtKB/Swiss-Pro... [more]
hsp-902.191e-9678.13Heat shock protein 90 [Source:UniProtKB/Swiss-Pro... [more]
hsp-902.191e-9678.13Heat shock protein 90 [Source:UniProtKB/Swiss-Pro... [more]
hsp-902.191e-9678.13Heat shock protein 90 [Source:UniProtKB/Swiss-Pro... [more]
enpl-13.091e-10545.08Endoplasmin homolog [Source:UniProtKB/Swiss-Prot;... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hsp839.103e-11577.25gene:FBgn0001233 transcript:FBtr0332873[more]
Hsp839.103e-11577.25gene:FBgn0001233 transcript:FBtr0073040[more]
Gp939.624e-10546.86gene:FBgn0039562 transcript:FBtr0085254[more]
Trap12.513e-4630.79gene:FBgn0026761 transcript:FBtr0086149[more]
Trap12.513e-4630.79gene:FBgn0026761 transcript:FBtr0336666[more]
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BLAST of Heat shock protein 90 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90aa1.11.908e-10776.85heat shock protein 90, alpha (cytosolic), class A ... [more]
hsp90aa1.11.908e-10776.85heat shock protein 90, alpha (cytosolic), class A ... [more]
hsp90ab13.786e-10878.88heat shock protein 90, alpha (cytosolic), class A ... [more]
hsp90ab13.786e-10878.88heat shock protein 90, alpha (cytosolic), class A ... [more]
hsp90aa1.24.311e-11277.08heat shock protein 90, alpha (cytosolic), class A ... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ccdc1730.000e+075.59coiled-coil domain containing 173 [Source:Xenbase;... [more]
ccdc1730.000e+075.59coiled-coil domain containing 173 [Source:Xenbase;... [more]
ccdc1730.000e+074.76coiled-coil domain containing 173 [Source:Xenbase;... [more]
ccdc1730.000e+073.08coiled-coil domain containing 173 [Source:Xenbase;... [more]
ccdc1730.000e+072.38coiled-coil domain containing 173 [Source:Xenbase;... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Hsp90aa15.106e-11177.30heat shock protein 90, alpha (cytosolic), class A ... [more]
Hsp90aa15.106e-11177.30heat shock protein 90, alpha (cytosolic), class A ... [more]
Hsp90ab12.645e-10876.58heat shock protein 90 alpha (cytosolic), class B m... [more]
Hsp90b12.343e-12148.80heat shock protein 90, beta (Grp94), member 1 [Sou... [more]
Hsp90aa14.214e-10482.45heat shock protein 90, alpha (cytosolic), class A ... [more]
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BLAST of Heat shock protein 90 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|P04809|HSP83_DROPS0.000e+074.97Heat shock protein 83 OS=Drosophila pseudoobscura ... [more]
sp|O61998|HSP90_BRUPA4.175e-10079.42Heat shock protein 90 OS=Brugia pahangi OX=6280 GN... [more]
sp|A5A6K9|HS90A_PANTR1.767e-10977.75Heat shock protein HSP 90-alpha OS=Pan troglodytes... [more]
sp|Q4R4P1|HS90A_MACFA2.224e-11077.75Heat shock protein HSP 90-alpha OS=Macaca fascicul... [more]
sp|P07900|HS90A_HUMAN2.169e-11077.75Heat shock protein HSP 90-alpha OS=Homo sapiens OX... [more]
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BLAST of Heat shock protein 90 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
C0KTP70.000e+092.1790 kDa heat shock protein OS=Dugesia japonica OX=6... [more]
A0A1S3JGM60.000e+079.44heat shock protein 83 OS=Lingula unguis OX=7574 GN... [more]
A0A0M4HFL90.000e+079.06Heat shock protein 90 OS=Macrostomum lignano OX=28... [more]
A0A267DD200.000e+079.20HATPase_c domain-containing protein OS=Macrostomum... [more]
E2B7J90.000e+078.37Heat shock protein HSP 90-alpha OS=Harpegnathos sa... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90aa1.21.111e-10777.13Astyanax mexicanus heat shock protein HSP 90-alpha... [more]
hsp90aa1.21.111e-10777.13Astyanax mexicanus heat shock protein HSP 90-alpha... [more]
hsp90ab11.159e-10978.15heat shock protein 90 alpha family class B member ... [more]
hsp90aa1.22.629e-11277.20Astyanax mexicanus heat shock protein HSP 90-alpha... [more]
hsp90aa1.23.442e-11277.20Astyanax mexicanus heat shock protein HSP 90-alpha... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
ENSPMAT00000003399.15.512e-8476.92pep scaffold:Pmarinus_7.0:GL479675:6143:15195:1 ge... [more]
hsp90b18.529e-10544.23heat shock protein 90, beta (grp94), member 1 [Sou... [more]
hsp90ab11.228e-9762.46heat shock protein 90, alpha (cytosolic), class A ... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
HSC822.734e-17562.33Cytoplasmic chaperone of the Hsp90 family; plays a... [more]
HSP826.706e-17361.21Hsp90 chaperone; redundant in function with Hsc82p... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
HSP900.000e+076.72Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO453447.344e-11349.28Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO456663.910e-4644.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Heat shock protein 90 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
hsp90ab10.000e+078.37heat shock protein 90 alpha family class B member ... [more]
hsp90ab10.000e+076.69heat shock protein 90 alpha family class B member ... [more]
hsp90aa1.29.080e-10878.65heat shock protein HSP 90-alpha [Source:NCBI gene;... [more]
hsp90aa1.27.675e-10878.43heat shock protein HSP 90-alpha [Source:NCBI gene;... [more]
hsp90aa1.29.272e-10878.20heat shock protein HSP 90-alpha [Source:NCBI gene;... [more]
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BLAST of Heat shock protein 90 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000071533.10.000e+099.86SMESG000071533.1[more]
SMESG000024822.10.000e+088.66SMESG000024822.1[more]
SMESG000071531.11.875e-13699.53SMESG000071531.1[more]
SMESG000025598.13.581e-11885.97SMESG000025598.1[more]
SMESG000041107.11.761e-11444.23SMESG000041107.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035193 ID=SMED30035193|Name=Heat shock protein 90|organism=Schmidtea mediterranea sexual|type=transcript|length=2392bp
ATTTATTCGAAATAGAACAAAATTTATTCTAATGGAATTTCTATATTTCT
ACATAGAACATAAATGTAGGTCAATAGAATTCTGATCGAATATTCTAGAA
TCTATTACTTTGTTATAAATTCGTATTATCGGCTTCCATATTCACTTTTT
AAATTTCATTTCAATATTAATTAGCAATATTTTGAAAAAAATGAGCGAGA
CTGATGCTGAAACGTTTGCATTCCAAGCTGAGATTGCTCAGTTGATGAGC
CTAATAATCAACACATTTTATTCGAATAAAGAAATTTTCCTTCGAGAATT
AATTTCAAATTCAAGTGATGCGTTAGACAAGATCCGCTACAAAAGTTTAA
CAGATCCATCAGTTTTGGATTCGGCCAAAGATTTAATGATTAAAATTATT
CCTGATAAAGATGCCGGAACTTTAACTATTGTCGACACCGGTATTGGTAT
GACGAAAGCGGATTTAATTAACAATTTGGGAACAATCGCAAGATCAGGTA
CTAAAGCTTTTATGGAAGCGTTGCAAGCCGGTGCTGACATATCTATGATT
GGTCAATTTGGTGTGGGTTTCTACTCGTCTTACCTTGTTGCAGATAAAGT
TCAAGTTATTTCAAAAAGTAATGATGATGAACAGTATTTATGGGAATCAT
CAGCTGGTGGTTCTTTCACAATTAAGTATGATAATTCTGAACCAATTGGT
AGAGGTTCTAAAGTGATATTGTACATGAAAGAAGATCAAATTGAATATTT
GGATGAGAAAAAAATCAAAGAAATCATTAAGAAGCATTCCCAATTTATTG
GCTATCCAATCAAGCTTGTTTTGGAAAAAGAAAGAGATAAAGAAATATCT
GATGATGAAGCTGAAGTAGATGATAAAAAAGAAAAGGAAAGTGAAGATAC
TGAAGATAAGCCGAAAATTGAAGACTTGGATGATGAGGAAGATGATGATA
AAAAAGATAAAGATAAAAAGAAAAAGAAAATTAAGGAAAAGTATATTGAT
GAAGAGGAGTTGAATAAAACTAAACCAATATGGACAAGAAATCCAGATGA
CGTCAGTCAAGAAGATTATGCTGAATTCTATAAATCCTTAACAAACGATT
GGGAAGATCATCTGGCTGTTAAGCATTTTTCTGTTGAAGGACAATTAGAA
TTCCGAGCTTTGTTGTTTTGTCCTAAACGAGCTCCTTTTGATTTATTTGA
AAATAAGAAGAAGCGTAACAATATCAAACTCTATGTTCGTAGAGTATTTA
TAATGGATAATTGTGAAGATTTAATTCCTGAGTATCTGAATTTTGTCAAA
GGTGTAGTTGATAGCGAGGATCTTCCATTGAATATTAGTCGTGAAATGCT
TCAACAAAACAAAATTTTGAAAGTAATCAGAAAAAATTTAGTCAAAAAAT
GTTTGGAACTATTTGAAGAAATAATGGAAGATAAAGATAATTATAAAAAG
TTCTATGAACAATTTGCTAAAAATATTAAATTAGGTATTCATGAAGATAG
TGTAAATAGAAATAAAATAGCAGAATTTTTGCGATTTTATTCAACGTCAA
GTGGTGAAGAAATGACAAGTTTGAAAGATTATATTTCTCGAATGAAAGAA
AATCAAAAGGATATTTACTATATTACTGGAGAAAGCAAAGATAATGTTAT
TCATTCAGCATTTGTTGAGAGATTGACTAAACGAGGATTTGAAGTGTTGC
TAATGGTTGATCCAATTGATGAATATAGTGTTCAACAATTGAAAGAGTAT
GATGGTAAAAAGTTGGTATGTGTAACTAAAGAGGGCTTAGAGCTACCTGA
AGATGAAGATGAAAAGAAAAAATTTGAAGAACAAAAAGCTGCTTTTGAAC
CGCTTTGTAAAGTTATGAAAGATATATTAGATAAAAAGGTCGAGAAGGTC
ACGGTTTCTAATAGATTGGTATCTTCTCCATGTTGTATTGTAACATCTCA
ATTTGGATGGTCAGCAAATATGGAAAGAATTATGAAGGCGCAAGCATTGC
GGGATAGTAGCACAATGGGATATATGGCTGCGAAAAAACACTTGGAAATT
AATCCTGATCATTCAATAATGAAATCTCTTAAATTGCGAGTTGATGCAGA
TAAAAATGATAAATCTGTGAAAGATCTTGTTATGCTATTATTCGAGACAT
CTTTGTTAAGCTCTGGATTTTCTTTAGAAGATCCACAAGTCCATGGTAAT
CGTATTCATAGAATGATAAAACTTGGCTTAGGAATCGAAGACGATGATGT
TGAAATTGATGCGACTGAAGCAGGAGATATTCCTGTAGGTCCTACGTCTA
CTGAAGATGAGGCTGGTAAAATGGAAGAGGTTGATTGAAAATAAAAATTA
TATTTTGTTGTGTAAATATAGTTAATTGATGTGAAAAAAAAA
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protein sequence of SMED30035193-orf-1

>SMED30035193-orf-1 ID=SMED30035193-orf-1|Name=SMED30035193-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=716bp
MSETDAETFAFQAEIAQLMSLIINTFYSNKEIFLRELISNSSDALDKIRY
KSLTDPSVLDSAKDLMIKIIPDKDAGTLTIVDTGIGMTKADLINNLGTIA
RSGTKAFMEALQAGADISMIGQFGVGFYSSYLVADKVQVISKSNDDEQYL
WESSAGGSFTIKYDNSEPIGRGSKVILYMKEDQIEYLDEKKIKEIIKKHS
QFIGYPIKLVLEKERDKEISDDEAEVDDKKEKESEDTEDKPKIEDLDDEE
DDDKKDKDKKKKKIKEKYIDEEELNKTKPIWTRNPDDVSQEDYAEFYKSL
TNDWEDHLAVKHFSVEGQLEFRALLFCPKRAPFDLFENKKKRNNIKLYVR
RVFIMDNCEDLIPEYLNFVKGVVDSEDLPLNISREMLQQNKILKVIRKNL
VKKCLELFEEIMEDKDNYKKFYEQFAKNIKLGIHEDSVNRNKIAEFLRFY
STSSGEEMTSLKDYISRMKENQKDIYYITGESKDNVIHSAFVERLTKRGF
EVLLMVDPIDEYSVQQLKEYDGKKLVCVTKEGLELPEDEDEKKKFEEQKA
AFEPLCKVMKDILDKKVEKVTVSNRLVSSPCCIVTSQFGWSANMERIMKA
QALRDSSTMGYMAAKKHLEINPDHSIMKSLKLRVDADKNDKSVKDLVMLL
FETSLLSSGFSLEDPQVHGNRIHRMIKLGLGIEDDDVEIDATEAGDIPVG
PTSTEDEAGKMEEVD*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000026gut
PLANA:0000034epidermis
PLANA:0000035Category 3 cell
PLANA:0000070intestinal phagocyte
PLANA:0000429neoblast
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR020575Hsp90_N
IPR003594HATPase_C
IPR001404Hsp90_fam
IPR019805Heat_shock_protein_90_CS
IPR020568Ribosomal_S5_D2-typ_fold
Vocabulary: biological process
TermDefinition
GO:0006950response to stress
GO:0006457protein folding
GO:0009408response to heat
GO:0009409response to cold
GO:0046677response to antibiotic
Vocabulary: molecular function
TermDefinition
GO:0005524ATP binding
GO:0051082unfolded protein binding
GO:0000166nucleotide binding
GO:0016887ATPase activity
Vocabulary: cellular component
TermDefinition
GO:0005634nucleus
GO:0005737cytoplasm
GO:0005886plasma membrane
GO:0016020membrane
GO:0042470melanosome