Blast:Endothelin-converting enzyme 1

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+++ C +++  I S +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    E  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y++ +  ++     + T   +L   + W ++        ++  DA  +F  E++  T K+ L  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C+++QY  Y +    +    T+GE+IADN G + AY A++++   N  E+  LP L LT +QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN   KC VW
Sbjct:   71 LGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLEQISTLI-----NTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEH-SLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 754          

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+++ C +++  I S +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    E  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y++ +  ++     + T   +L   + W ++        ++  DA  +F  E++  T K+ L  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C+++QY  Y +    +    T+GE+IADN G + AY A++++   N  E+  LP L LT +QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN   KC VW
Sbjct:   87 LGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLEQISTLI-----NTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEH-SLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770          

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+++ C +++  I S +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    E  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y++ +  ++     + T   +L   + W ++        ++  DA  +F  E++  T K+ L  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C+++QY  Y +    +    T+GE+IADN G + AY A++++   N  E+  LP L LT +QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN   KC VW
Sbjct:   84 LGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLEQISTLI-----NTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEH-SLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 767          

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+++ C +++  I S +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    E  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y++ +  ++     + T   +L   + W ++        ++  DA  +F  E++  T K+ L  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C+++QY  Y +    +    T+GE+IADN G + AY A++++   N  E+  LP L LT +QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN   KC VW
Sbjct:   75 LGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLEQISTLI-----NTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEH-SLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 758          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNL-NLRNKETRPT--ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILG-LWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKS--ELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
             C+ + C  ++G+I   +D  V PC+D   F CG   +   +P G SR+++ + +       + +LLE     + S+ + K   FY SCL +  +     +P   ++E + G+ +   + +DN +  L+    T R   F  V    D  +   N++Q+ +  L L       +  A EK  +T+Y  +M ++  +LG    + +  +  ++ L I+LA        + +  K  +K+ ISE+Q+    + W++ ++ ++  S  ++ + + + V+ +DY+  +  ++     + T+  +L   L W ++         +   A  +    + G T KS    W+TC+S T + L   + S++VKA+FD   K+  E MI+ I+ A +  + ++ WMD +T+  A  K +AI + IG+PD +L    + + Y   +++E+ F +N ++   FS   +   + +   +D+W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD +G LR WW   S   +   T C+ +QY QY++    L   QT+GE+IADN G + AY A+K++     E   LP + LT  QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  +F + F C     MN  + C VW
Sbjct:   64 TCLTEACIRVAGKILESLDRGVSPCEDFYQFSCGGWIRRNPLPDGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAEQKTQRFYLSCLQVERIEELGAQPLRDLIEKIGGWNITGPWDQDNFMEVLKAVAGTYRATPFFTVYISADSKSSNSNVIQVDQSGLFLPSRDYYLNRTANEK-VLTAYLDYMEELGMLLGGRPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPSMDWLEFLSFLL--SPLELSDSEPVVVYGMDYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDRRFESAQEKLLETLYG-TKKSCVPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMISEIRTAFEEALGQLVWMDEKTRQAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEISEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYARNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLAAFRNHTACMEEQYNQYQVNGERLNGRQTLGENIADNGGLKAAYNAYKAWLRKHGEEQQLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 736          

Query:  231 KVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGF----LLNKKYEDNLLNFLQFGLATRM-----VSFE--AVQDPFNPEFNMLQIGKPSLILSEGTLQSS-EDALEKEQITSYTKFMNKVLDIL----GLWQNEKHI---IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVF---------SLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEK-----FLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKI--YNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNL-NLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +VC    C   +    + ++T+VDPCDD   F CG  +  + IP     + + +     V  ++  LLE Q +   S+    A   Y+SC+N    ++     + E L       LL + ++    NF    + +R      V F+     D  N   N L I + +L L  GT        L    +T+Y K++ ++  +L     L ++E  +   I  I++  I+LAK   +  ++ N  +  NK +I ++ +   ++ W+     +           DL ++F          ++Y+  +  ++++     T + +L   + W V+   V    E+  D    F   + G       WK C  V S VL     +IYV+A F  S K +   MI +++ +   ++ +  WMD ETKA A+ K  ++ N IGYPD       +  +Y  + +++         K+ V  Q   F +L +       K ++D+    VNA+Y+P  N I FPA  L+ P +    P + NYGAIG+VIGHEI HGFD  GS+YD  G L  WWS+SS   +  + +CI++QYG Y +   N  +    T GE+IADN G + A+ A++ Y + + E   LP L   T +Q+FF+  A  WC   K  A ++++  D H+   +R+ G  SNM  F+  +KC R+  +N   KC+VW
Sbjct:  159 EVCSTPGCVRAATHFLNAMNTSVDPCDDFFEFACGQWNDQHPIPDDMYGFGTFAYAREQVRQQLRVLLE-QEVVTESESINMARATYRSCMNKTQLDELMTGPLFETLTELGEWPLLQENWDKTKFNFTSLLVNSRRDYGVDVFFQLYIYADSKNTSRNTLFIDQSTLALGRGTRDYYLNTTLFSSHMTAYRKYLRQIAHLLKTDGNLTRSESEMNADIEKIIDFEIELAKIIVAEDERRNNTRLYNKRQIQDLYNLLPQVDWVPFFQSIAPS--------DLTHLFHNETEIIICEIEYLQHVSELIEK-----TDVGLLTNYVLWRVVQSNVRYLDERFEDIKQDFLKVMTGQQQSPPRWKDCAQVPSTVLPLAAGAIYVQAHFQESDKHEALRMIMHLRNSFADLVRQNDWMDEETKAVAIEKANSMINNIGYPDVTNDLPKLDKQYLGLSISDSDTYYYIMKKSVVWMQSREFQKLTKPFD----KHEFDISPAVVNAFYSPEKNAITFPAGILQPPFFSGTFPKAVNYGAIGAVIGHEITHGFDDQGSQYDKDGNLHNWWSESSLNSFDTRRRCIVEQYGNYTVPKTNFRVNGKLTQGENIADNGGVKEAFQAYQKYVTENGEEPRLPGLQQYTNEQIFFVSYAHFWCGKKKEAAAMQQVLTDEHSPEVFRVIGVLSNMQAFADVYKCPRNAPVNPDHKCIVW 848          

Query:  228 SKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLE--IQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGF-----LLNKKYEDNLLNFLQFGLATRMVS---FEAVQDP--FNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIG-NIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKG----SGKQMKEDD--LINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEW-----AVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKI--YNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLV-LPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            S VC++  C   +  I S ++++VDPCDD   F CG   K + IP       +   +  ++   +  LL+   +P    +    KA  FY  CLN +      R T  E +  F     L ++   D  +  L   +  +  +   F+A   P   N + ++L I +P L L          A E E+  +Y + +  VL +L   +    +    I++    LA    +   + +  +   K+ + E++      +W    N + K     +GK++  DD   + V+  +++  L  ++ +Y N     +++   LEW      ++ DL     +       +F   +  +  +   W  CV+  ++++    S+IYVK  FD   K+ +E MI+ I ++   ++    W+  ETK TA  K+  +  KIGYPD L   + ++N+Y++ K+    + +    F +     +L+ + E + +++W  G+  VNA+Y+P++NEI+FPA  L+   Y    P+S N+G IG VIGHEI HGFD  G  YD+ G +R+WW  ++  ++  K QCI  QY  Y +   N+ +    T GE+IADN G + AY A+K Y         LP +NLT DQLFFL  A+ WC  +     + K++   H+    R+ GP SN  +F+KA+ C     MN  +KC VW
Sbjct:   50 SDVCLSPGCIKTASVILSSMNSSVDPCDDFYEFACGQWIKGHPIPDDAPSVSNFENLGQDLEFALKELLDENDEPYDYETSAVGKAKYFYNLCLNESEILDNWRTTFDEVVKSFGGWPSLGHQMKPDASIEMLYADMVAKFKADSLFKATVQPDDKNSQRHVLLIDQPQLNLFARDFYV---AAENEERMAYLQLIRDVLILLDADRTRATLDAKEIIDFETALANITMADEHRHDIAELYTKITLGEMRRSLPHFNWPLFFNRMFKDLHEKNGKRITFDDNTEVVVYGYEFLRRLDVLIPQYDN-----RLIVNYLEWCWFFKTMLRDL----PDPFALTIFKFYKTLNIMNVQKVRWHGCVTRINSLMPMATSAIYVKNHFDHEAKQQVEEMISLIMESFVDLLLSEDWLTKETKQTAKQKVNEMKRKIGYPDYLNDPAAVNNEYKTFKVYPGHYYQTKFSFYEQYQRDVLERITEAVDRERWVAGAALVNAFYSPNTNEIIFPAGILQPVFYSKDFPSSMNFGGIGVVIGHEITHGFDDRGRLYDNLGNIRQWWDNATISKFEHKAQCIEKQYSSYVLDQINMQINGKSTKGENIADNGGLKQAYRAYKKYEKRHSRPPRLPGVNLTHDQLFFLNYAQIWCGTMNDKEAIRKLRTSEHSPGPIRVKGPLSNSYDFAKAYNCEPGSQMNPREKCRVW 736          

Query:  273 IKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGF-----LLNKKYED---NLLNFLQFGLATRMVS----FEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKE-QITSYTKF-MNKV---LDILGLWQNEKHI---IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDL-INGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVD-----FQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLP--SIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNL-NLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            ++  ++ ++DPCDD   + C      + IP   + Y   +     V  E+  L E       S+        Y +C++    N      +LE +  +     + N+K+ +   +L   L   + +R VS    F   +D  N    +L   + SL L   T     D  + E Q+ +Y K+ + KV    +  G+  NE  I   +  I+    + A+   +  D+ N  K  N  +  +++   S I W  L ++         +K +  I +  ++Y+  +  +L+   N D ++    + L WA          ++  D   +F  ++ G   +   WK CVS     LS    S+YV+  FD + K     MI ++++A ++++    WMD+ETK  AL K + +  +IGYPD +L++  + + Y+ ++   E      V+        F + +LL+ V     + ++   +  VNA+Y+P+ N I FPA  L+ P +D   P + NYG IG+VIGHEI HGFD  G ++D+ G LR+WW  ++  +++++TQCII+QY   K+    L      T GE+IADN G + A+ A+KSY   +  +   LP   +LT +QLFF+G A+ WC    P      +  D H+    R+N   +N PEF++AFKC     MN  K+C+VW
Sbjct:   76 LQKSLNLSLDPCDDFFEYACRAWVDSHPIPDDLTSYSQFTATREKVLAEMRKLYEDNTSIPTSKSIALIKQIYNTCMDTEKHNAVGARDLLEKIKTYGYWPMVHNEKWRESTFDLTKLLSNTIQSRDVSVFFDFGPAEDSRNVSRRLLSFDQGSLGLGYSTRDYYLDEKKYEKQMKAYRKYTIGKVRYYTEDAGMAVNESKIESDVDEIIAFEKEWAQILVAEEDRRNYTKLYNVRRFDDLKEYMSIIDWKKLTLSTTPFLVHSYLKTNPSIIISDVEYLQKMNTLLQ---NTDPRIVTNYILLRWA--GSWSQEIGKKYEDLQQEFAFQMYGRKQRQPRWKDCVSSAGGKLSYASGSMYVRKYFDANAKNTTLDMITDLQEAFRNMMHANDWMDAETKKYALEKADQMLKQIGYPDFILNDEKLDDWYKGLEGAPEDSFSQLVEKSIQWRNNFYYRRLLEPVN----RFEFISSAAVVNAFYSPTRNAIAFPAGILQQPFFDARFPKALNYGGIGAVIGHEITHGFDDTGRQFDNVGNLRDWWDNTTSSKFNERTQCIIEQYADVKLRGTDLRINGKLTQGENIADNGGIKQAFKAYKSYLEKHGGQEARLPQFESLTNEQLFFVGYAQVWCGAKTPETKTLLLLTDPHSPETARVNTVLTNQPEFAEAFKCPAGSPMNPTKRCVVW 754          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEALNGFLL---------NKKYEDNLLNFLQF-GLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILG----LWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGV--TGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQK-KDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIY--NVSLPSIQTVGEDIADNAGTRM---AYIAWKSYSNDKENLVLPNL-NLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            VC +  C  L+G +   +++ ++PC+D   F CGN     ++P  +    + S ++  +N ++ ++L+     N       A  +Y+ CL+   L     E    I + + G+           +  +E+ +   L   G+   ++      DP N   +++++ +P      G+            + +YT  M      LG    + + E   +   +   +KL         + +P +  N+ ++ +++S    I++   +  V K     +  +  + V  +DY   +  +L+      T  +VL   + W ++    P       +   QF++   G+  +   + W+ CV+++  ++   V  ++V+  F+  +  K +  + + +K      +  + WMD  T+  A+ K   I  K G+P  L ++++M   +  I    E  L   +  +   F + L  + + + +  W     +V+AYY P++NE++FPA  +++P   +G+PN   YG +G+VIGHE+ H FD  G +YD  G L +WW   + E++ +KT+C + QY    +   ++ L    ++GE+IADN G +    AY AWKS +       LP   N T+ Q+FFL  A  WC+LV+P   ++ +  DVH   KYR   P  N PEF+KAF+C     MN  +KC VW
Sbjct:   85 VCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKW--GAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKE---MNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFK-ELVALSPNHTVIVREIDYFVGIQHVLQ-----STPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYLLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 769          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEALNGFLL---------NKKYEDNLLNFLQF-GLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILG----LWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGV--TGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQK-KDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIY--NVSLPSIQTVGEDIADNAGTRM---AYIAWKSYSNDKENLVLPNL-NLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            VC +  C  L+G +   +++ ++PC+D   F CGN     ++P  +    + S ++  +N ++ ++L+     N       A  +Y+ CL+   L     E    I + + G+           +  +E+ +   L   G+   ++      DP N   +++++ +P      G+            + +YT  M      LG    + + E   +   +   +KL         + +P +  N+ ++ +++S    I++   +  V K     +  +  + V  +DY   +  +L+      T  +VL   + W ++    P       +   QF++   G+  +   + W+ CV+++  ++   V  ++V+  F+  +  K +  + + +K      +  + WMD  T+  A+ K   I  K G+P  L ++++M   +  I    E  L   +  +   F + L  + + + +  W     +V+AYY P++NE++FPA  +++P   +G+PN   YG +G+VIGHE+ H FD  G +YD  G L +WW   + E++ +KT+C + QY    +   ++ L    ++GE+IADN G +    AY AWKS +       LP   N T+ Q+FFL  A  WC+LV+P   ++ +  DVH   KYR   P  N PEF+KAF+C     MN  +KC VW
Sbjct:   85 VCTSRECVRLAGFLAENLNSKINPCEDFYEFACGNYGLNKNLPANKPLRHTISDVQSRLNKQVKSMLQSPISANEKPWDKVAKGYYQKCLDEEELESTGVEAMRDIAKRIGGWPTLEGDKWQEWSHSWEEQIALVLNLTGVNAVILEMAVTHDPSNSSRSVIELDQPKW--GAGSRYPYLSGANDPMLRNYTTLMKMTAVALGADPAIAEKE---MNEAMEFELKLVNFSADDMVRRDPERGNNRFELWQLKSVFPFINFEKYLKTVFK-ELVALSPNHTVIVREIDYFVGIQHVLQ-----STPKRVLANYISWRLVQGFSPFLPPSAREPFYQFKANQTGMFNSPPPDRWEDCVTLSVIMMDMPVGRLFVENFFEKERAMKKMTELTSYLKNEFIKQLHVLDWMDEITRRRAISKANMIEYKSGFPMVLFNDTWMEKNWGMIIKPREYLLHLTIRVKLVRFTEELLRLDQPLDRSMWFQSPAQVDAYYAPNNNEMIFPAGIMQFPFLTLGVPNYITYGMVGAVIGHEVSHAFDDQGGQYDEMGNLNDWWDAETEEKFIEKTRCFVRQYENVHVVEADIHLNGQLSLGENIADNGGVKTAFNAYKAWKSNTTGISEPALPGFQNFTSQQMFFLAYANNWCSLVRPKHYIQIILTDVHAPSKYRAMIPLQNRPEFAKAFQCPIGSPMNPERKCQVW 769          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN--LRNKETRPT--ILEALNGF-------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+N  C   S EI   +D TVDPCDD   + C    K   IP+G+S + +  ++E      I N+LE       S  + KA ++Y+SCL+ +  +     +P   +L  + G+                   +L+ KY  N L    FG A         +D  N   +++QI +  L L      +++    ++ +  Y ++M KV  +LG  +++    +IG ++N   KLA     + D+ N     + +++ ++      ++W D  +  M+  G+++ +D+++ V++ D++  L  I+ + +  +     L   L W  +  L    S+   DA+   +  ++G  G  E+W+ CVS T+NV+   V +I+V+ +F    K   E MIA I++A K  ++ +TW+D +T+  A+ K   I++ IG+PD +L    +  KY  + +T   + +N +    ++    L+ + + + K  W M    VNAYY P+ N+IVFPA  L+ P +DI  P S N+GA+G V+GHE+ H FD  G +YD  G +  WW   S E +++K++CI  QY  YK+   +L   QT+GE+IADN G + AY A++   +D++   L LP LNLT  QLFF+  A+ WC+       L +M+ D H+  ++R+ G  SNM EF++ F+C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCL----FGWAIG-------EDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN--LRNKETRPT--ILEALNGF-------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+N  C   S EI   +D TVDPCDD   + C    K   IP+G+S + +  ++E      I N+LE       S  + KA ++Y+SCL+ +  +     +P   +L  + G+                   +L+ KY  N L    FG A         +D  N   +++QI +  L L      +++    ++ +  Y ++M KV  +LG  +++    +IG ++N   KLA     + D+ N     + +++ ++      ++W D  +  M+  G+++ +D+++ V++ D++  L  I+ + +  +     L   L W  +  L    S+   DA+   +  ++G  G  E+W+ CVS T+NV+   V +I+V+ +F    K   E MIA I++A K  ++ +TW+D +T+  A+ K   I++ IG+PD +L    +  KY  + +T   + +N +    ++    L+ + + + K  W M    VNAYY P+ N+IVFPA  L+ P +DI  P S N+GA+G V+GHE+ H FD  G +YD  G +  WW   S E +++K++CI  QY  YK+   +L   QT+GE+IADN G + AY A++   +D++   L LP LNLT  QLFF+  A+ WC+       L +M+ D H+  ++R+ G  SNM EF++ F+C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCL----FGWAIG-------EDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN--LRNKETRPT--ILEALNGF-------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+N  C   S EI   +D TVDPCDD   + C    K   IP+G+S + +  ++E      I N+LE       S  + KA ++Y+SCL+ +  +     +P   +L  + G+                   +L+ KY  N L    FG A         +D  N   +++QI +  L L      +++    ++ +  Y ++M KV  +LG  +++    +IG ++N   KLA     + D+ N     + +++ ++      ++W D  +  M+  G+++ +D+++ V++ D++  L  I+ + +  +     L   L W  +  L    S+   DA+   +  ++G  G  E+W+ CVS T+NV+   V +I+V+ +F    K   E MIA I++A K  ++ +TW+D +T+  A+ K   I++ IG+PD +L    +  KY  + +T   + +N +    ++    L+ + + + K  W M    VNAYY P+ N+IVFPA  L+ P +DI  P S N+GA+G V+GHE+ H FD  G +YD  G +  WW   S E +++K++CI  QY  YK+   +L   QT+GE+IADN G + AY A++   +D++   L LP LNLT  QLFF+  A+ WC+       L +M+ D H+  ++R+ G  SNM EF++ F+C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCL----FGWAIG-------EDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNE---IHNLLEIQPLQNHSQHQT-KAALFYKSCLNL-NLRNKETR--PTILEALNGF-LLNKKYE-------DNLLNFLQFGLATR-MVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGL------WQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVS--LPSIQTVGEDIADNAGTRMAYIAWKSYSN-DKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+   C   +  + S +D   DPC+D   + CG  +K++ IP+  S   S S  E+  + +   +  +LE +P+       T KA  F+KSC+++  +R   T     +L++L G+ ++ + +        + L+  L+   +   M+      D  N   N+LQ+ +    L        E +    +  +Y ++M +V  +LG        + EK ++     +N+ L +     AD+ + +    K+ + E+Q    E+ W + +   + G G  ++ED+ +  + L Y+  +  IL       T  +V+   + W ++  L+    ++      +F+  ++G+  +   W  CV  T+  L   V +++++ +F+   K+    MI  I+ A   ++ E  WMD ET+A A  K +++  +IGYP+ L + + +  +Y ++ +  + F+ N +   ++   ++L+ + + + K+KW      VNA+YNP+ N+IVFPA  L+   Y    P S NYG IG VIGHEI HGFD  G ++D +G + +WW+ ++ E + ++TQC+IDQY +YKI  V   +    T GE+IADN G + A+ A+K +         LP LN+T DQLFFL  A+ WC  ++P   L K++  VH+    R+ GP SN  +F+ A+KC     MN  +KC VW
Sbjct:  172 ICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRS---SISTFEVLSDQQQVILRAVLE-EPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRR--AYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPE-----ADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAAL-GPGIPLQEDEPLVTYGLHYLTEMGKILAH-----TDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNE---IHNLLEIQPLQNHSQHQT-KAALFYKSCLNL-NLRNKETR--PTILEALNGF-LLNKKYE-------DNLLNFLQFGLATR-MVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGL------WQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVS--LPSIQTVGEDIADNAGTRMAYIAWKSYSN-DKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+   C   +  + S +D   DPC+D   + CG  +K++ IP+  S   S S  E+  + +   +  +LE +P+       T KA  F+KSC+++  +R   T     +L++L G+ ++ + +        + L+  L+   +   M+      D  N   N+LQ+ +    L        E +    +  +Y ++M +V  +LG        + EK ++     +N+ L +     AD+ + +    K+ + E+Q    E+ W + +   + G G  ++ED+ +  + L Y+  +  IL       T  +V+   + W ++  L+    ++      +F+  ++G+  +   W  CV  T+  L   V +++++ +F+   K+    MI  I+ A   ++ E  WMD ET+A A  K +++  +IGYP+ L + + +  +Y ++ +  + F+ N +   ++   ++L+ + + + K+KW      VNA+YNP+ N+IVFPA  L+   Y    P S NYG IG VIGHEI HGFD  G ++D +G + +WW+ ++ E + ++TQC+IDQY +YKI  V   +    T GE+IADN G + A+ A+K +         LP LN+T DQLFFL  A+ WC  ++P   L K++  VH+    R+ GP SN  +F+ A+KC     MN  +KC VW
Sbjct:  172 ICMTQECVRTAASLLSAMDLNSDPCEDFFQYACGTWNKMHPIPEDRS---SISTFEVLSDQQQVILRAVLE-EPIDERDNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLSVERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESSANDRR--AYHRYMTQVALLLGADPATAAAELEKVVLFETQLVNVSLPE-----ADRHDTSLVYRKMLLPELQELVPEVQWQEYLQAAL-GPGIPLQEDEPLVTYGLHYLTEMGKILAH-----TDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNKKLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAENDWMDDETRAVAKEKADSMNERIGYPELLTNATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLRQPVDKEKWTTEPAVVNAFYNPNKNDIVFPAGILQPLFYSQHFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVDMFMDGRMTQGENIADNGGLKQAFRAYKKWETLHGREQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW 849          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRP--TILEALNGFLLNKKYE-DNLLNFLQF-GLATRMVSFEAVQ---DPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQ---ITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKS--ELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+ + C T++ +I   +D + DPC D   + CG   +   +P G SR+ + + I       + +LLE     + S+ + K   +Y SCLN   +     +P   ++  + G+ + + ++ +N L+ L+      R   F  V    DP N   N++Q+ +  L L      S +  L K     + +Y  +M ++  +LG  +N  +  +  I++    LA       ++ +  K  +K+ I+++Q     I W+D +N V+  S  ++ + + + V++ +Y+  +  ++ +     T   +L   + W ++        ++  +A ++    + G T KS    W+TC+  T + L   + +++VKA+FD   K+  E MI  I+ A K  ++++ WMD +T+  A  K +AI + IG+PD +L    + + Y   ++TE+ F +N ++F  FS   +   + +   +D+W M    VNAYY P+ N IVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E +  +T+C++DQY QY I    +   QT+GE+IADN G + AY A++S+   + E   LP +NLT DQLFF+G A+ WC++  P +  E +  D H+  KYR+ G  SN PEF++ F+C    +MN   +C VW
Sbjct:   94 ICLTEACVTVASKIVEALDRSADPCQDFYQYACGGWVRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAERKTQSYYLSCLNEQRIEELGAQPLMDLITKIGGWNITESWDKENFLDVLKIISGPYRAQPFFTVSVSVDPKNSNSNVIQVDQSGLFLP-----SRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTRGQMQQILDFETALANITVPQDERRDEEKIYHKITIADLQVLAPAIEWLDYLNSVL--SPLELNDTEPVVVYAKEYMQQVSELINK-----TDHSLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYG-TKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKQSKEIAEGMINEIRTAFKGALDDLKWMDEQTRQAAKDKADAIYDMIGFPDFILDSKELDDVYDGYEVTEDNFFQNMINFYNFSARVMADQLRKPPNRDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAQDHPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRSWWQNSSVEAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVQKNGEEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPEFAEHFQCPLGSSMNSGHRCEVW 765          

Query:  195 LPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN-LRNKETRPT--ILEALNGFLLNKKYE-DNLLNFLQFGLATRMVSFEAVQDPFNPEF----------NMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQN-EKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + + +  + +   +C+++ C +++  +   +D +VDPC D   F CG   +   +P+G+SR+   S +  +    + NLLE   +++ S+ + KA  +Y++C+N + +     +P   ++    G+ L   +E DN    L      R+VS      PF   F          N++Q+ +  L L       ++ A EK  + +Y  F+ ++  +LG  Q+  + ++  I+     LA       ++ +  K   K++  E+ +    I W+  ++ V   +  ++ + + + V++ +Y+  +  ++      +T   VL   +   V+  +V +  ++  DA  +F  E++  T KS +  WK CVS T + L   + +++VKA+F    K  +E M++ IK A +  ++ V+WMD ETK  A  K +AI N +GYP  +++   +   +    +  + + +N +++  FS       + +   +D+W M    VNAYYNP+ NE+V PA   + P Y+   P + N+G IG V+GHE+ H FD  G KYD  G L +WW  SS E +  +TQC+++QY  Y I N  L    T+GE+IADN G   AY A+ ++   + E   LP L +   QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F C  D  MN  +KC +W
Sbjct:   67 MSLGLHYKESHPGLCLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLINQTGGWGLKGPWEKDNFQEVL------RIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTANEK-YLNAYLNFLVELGVLLGGSQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKELATLAPAIDWMPFLSSVF--APVELNDSEPVVVYAKEYLQKVSELI-----SNTNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFL-EVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNPKRKCELW 752          

Query:  195 LPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN-LRNKETRPT--ILEALNGFLLNKKYE-DNLLNFLQFGLATRMVSFEAVQDPFNPEF----------NMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQN-EKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + + +  + +   +C+++ C +++  +   +D +VDPC D   F CG   +   +P+G+SR+   S +  +    + NLLE   +++ S+ + KA  +Y++C+N + +     +P   ++    G+ L   +E DN    L      R+VS      PF   F          N++Q+ +  L L       ++ A EK  + +Y  F+ ++  +LG  Q+  + ++  I+     LA       ++ +  K   K++  E+ +    I W+  ++ V   +  ++ + + + V++ +Y+  +  ++      +T   VL   +   V+  +V +  ++  DA  +F  E++  T KS +  WK CVS T + L   + +++VKA+F    K  +E M++ IK A +  ++ V+WMD ETK  A  K +AI N +GYP  +++   +   +    +  + + +N +++  FS       + +   +D+W M    VNAYYNP+ NE+V PA   + P Y+   P + N+G IG V+GHE+ H FD  G KYD  G L +WW  SS E +  +TQC+++QY  Y I N  L    T+GE+IADN G   AY A+ ++   + E   LP L +   QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F C  D  MN  +KC +W
Sbjct:   67 MSLGLHYKESHPGLCLSEPCVSVASAVLGSLDRSVDPCQDFYNFACGGWMRKNPLPEGKSRWGPFSNLWEHNMAVMKNLLENTSMKSLSRAEQKAQWYYQACMNESKIEELGAKPLQDLINQTGGWGLKGPWEKDNFQEVL------RIVSANFRTSPFFTVFVSTDSKSSNSNIIQVDQSGLGLPSREYYLNKTANEK-YLNAYLNFLVELGVLLGGSQDTSQKMMEEIIEFETTLANITVPQVERRDEEKIYYKIQAKELATLAPAIDWMPFLSSVF--APVELNDSEPVVVYAKEYLQKVSELI-----SNTNKSVLNNYMIMKVVRKMVSILDQKFQDAEQRFL-EVMYGTKKSCMPRWKLCVSDTDSALGFALGALFVKATFSEDSKAFVEDMVSEIKWAFEDSLKTVSWMDPETKKAAKEKADAIYNMVGYPKFIMNPKELDKVFNDFDVVSDLYFQNVMNYYNFSARVTADQLRKAPNRDQWSMTPPTVNAYYNPTKNEMVLPAGIFQAPFYNHAWPKAMNFGGIGVVMGHELTHAFDDQGRKYDKDGNLAKWWQNSSVEAFQHQTQCMVEQYSNYSINNEPLNGKHTLGENIADNGGLNAAYKAYVNWIKKNGEEASLPALGMNNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSHEFSEHFGCKADSPMNPKRKCELW 752          

Query:  222 AFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRPTIL------------EALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFN--MLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDIL----GLWQNEKHII---GNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQS--RCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSES--YMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKI-----YNVSLPSIQTVGEDIADNAGTRMAYIAW-KSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            A S VC    C T +  +   +D +VDPC +   + CG   + + IP+  S +   + +   +   +  +LE++   +    + KA   Y SC+N + +  ++++P +             E  NG        ++ L  L  G   +    E    P + + +  ++ + +P+L +       S+   +K +  +Y +FM  +  I      L Q+E+ ++     ++ L   +A       ++++     NK+ + E Q     +  +W   I G+M      ++ D+ I ++   Y++ L  +L ++ +     + L+  L W +I D V   S +  D    ++  + G T +   W+ CV      +   V ++YV+ +F  + K+ +  +I  I++A    +EE++WMD ++K  A  K  AI+ +IGYPD +L E    +  +Y  +  +EE + +N ++    S  +  + + E +  D W +G+  VNA+Y+ + N+IVFPA  L+ P +      + N+G IG VIGHEI HGFD  G  +D  G +  WWS  S E +  +++C+++QYG++        NVS   I T+GE+IADN G R AY A+ K    + E   LP L++   QLFFL  A+ WC   +P   ++ +K D H+  +YR+ G   N   FS+AF C R   MN  +KC VW
Sbjct:   60 ADSNVCTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERHVIPETSSLHSVFNILRDELEIVLKGVLEMENKDDREAFK-KAKTLYSSCMNEILIEQRDSQPLLRLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLN-GRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGNYKKVR-EAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLSKHSH-----RTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVS--GITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW 755          

Query:  222 AFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRPTIL------------EALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFN--MLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDIL----GLWQNEKHII---GNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQS--RCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSES--YMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKI-----YNVSLPSIQTVGEDIADNAGTRMAYIAW-KSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            A S VC    C T +  +   +D +VDPC +   + CG   + + IP+  S +   + +   +   +  +LE++   +    + KA   Y SC+N + +  ++++P +             E  NG        ++ L  L  G   +    E    P + + +  ++ + +P+L +       S+   +K +  +Y +FM  +  I      L Q+E+ ++     ++ L   +A       ++++     NK+ + E Q     +  +W   I G+M      ++ D+ I ++   Y++ L  +L ++ +     + L+  L W +I D V   S +  D    ++  + G T +   W+ CV      +   V ++YV+ +F  + K+ +  +I  I++A    +EE++WMD ++K  A  K  AI+ +IGYPD +L E    +  +Y  +  +EE + +N ++    S  +  + + E +  D W +G+  VNA+Y+ + N+IVFPA  L+ P +      + N+G IG VIGHEI HGFD  G  +D  G +  WWS  S E +  +++C+++QYG++        NVS   I T+GE+IADN G R AY A+ K    + E   LP L++   QLFFL  A+ WC   +P   ++ +K D H+  +YR+ G   N   FS+AF C R   MN  +KC VW
Sbjct:   70 ADSNVCTTPQCVTAAARLLQNMDPSVDPCQNFYQYACGGWIERHVIPETSSLHSVFNILRDELEIVLKGVLEMENKDDREAFK-KAKTLYSSCMNEILIEQRDSQPLLRLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLN-GRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGNYKKVR-EAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLSKHSH-----RTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQGNMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELSWMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLREPVDPDMWIIGAAVVNAFYSHNRNQIVFPAGILQPPFFSEKQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVS--GITTLGENIADNGGVRQAYKAYVKWVEREGEEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW 765          

Query:  201 IAILVQSAFSK---VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETR----PTILEALNGFLLNKKYE-DNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI-IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            IA+ VQ    +   +C+++ C +++G I   +D  +DPC D   + CG   +   +P G SR+++ + I       + ++LE     + S+ + K   FY SCL    R +E R      ++E + G+ ++  +  +N ++ L+    T R   F +V    D  +   N++Q+ +  L L       ++ A  K  + +Y ++M  V ++LG       + +  I+     LA       ++ +  K  N++ ISE+QS      W+D +   +  S   + + + + V+  +Y+  +  ++     ++T   +L   L W ++  +      +   A ++    + G     +  W+TC+S T + L   + S++VK++FD + K   E MI+ I+ A +  +  +TWMD +T+  A  K +AI + IG+PD +L    +   Y   +++E+ F +N ++F  FS   + + + +   +++W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E +  +T+C+++QY  Y +    +   QT+GE+IADN G + AY A+KS+     E   LP + LT +QLFF+G A+ WC++  P +  E +  D H+  K+R+ G  SN  +F++ F C +   MN  K C VW
Sbjct:   78 IALGVQQMTDRSRSLCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLK-EQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGK-VLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFAL--SPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 764          

Query:  201 IAILVQSAFSK---VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETR----PTILEALNGFLLNKKYE-DNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI-IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            IA+ VQ    +   +C+++ C +++G I   +D  +DPC D   + CG   +   +P G SR+++ + I       + ++LE     + S+ + K   FY SCL    R +E R      ++E + G+ ++  +  +N ++ L+    T R   F +V    D  +   N++Q+ +  L L       ++ A  K  + +Y ++M  V ++LG       + +  I+     LA       ++ +  K  N++ ISE+QS      W+D +   +  S   + + + + V+  +Y+  +  ++     ++T   +L   L W ++  +      +   A ++    + G     +  W+TC+S T + L   + S++VK++FD + K   E MI+ I+ A +  +  +TWMD +T+  A  K +AI + IG+PD +L    +   Y   +++E+ F +N ++F  FS   + + + +   +++W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E +  +T+C+++QY  Y +    +   QT+GE+IADN G + AY A+KS+     E   LP + LT +QLFF+G A+ WC++  P +  E +  D H+  K+R+ G  SN  +F++ F C +   MN  K C VW
Sbjct:   69 IALGVQQMTDRSRSLCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLK-EQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGK-VLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFAL--SPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 755          

Query:  201 IAILVQSAFSK---VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETR----PTILEALNGFLLNKKYE-DNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI-IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            IA+ VQ    +   +C+++ C +++G I   +D  +DPC D   + CG   +   +P G SR+++ + I       + ++LE     + S+ + K   FY SCL    R +E R      ++E + G+ ++  +  +N ++ L+    T R   F +V    D  +   N++Q+ +  L L       ++ A  K  + +Y ++M  V ++LG       + +  I+     LA       ++ +  K  N++ ISE+QS      W+D +   +  S   + + + + V+  +Y+  +  ++     ++T   +L   L W ++  +      +   A ++    + G     +  W+TC+S T + L   + S++VK++FD + K   E MI+ I+ A +  +  +TWMD +T+  A  K +AI + IG+PD +L    +   Y   +++E+ F +N ++F  FS   + + + +   +++W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E +  +T+C+++QY  Y +    +   QT+GE+IADN G + AY A+KS+     E   LP + LT +QLFF+G A+ WC++  P +  E +  D H+  K+R+ G  SN  +F++ F C +   MN  K C VW
Sbjct:   80 IALGVQQMTDRSRSLCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLK-EQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGK-VLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFAL--SPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGFEVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 766          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETR----PTILEALNGFLLNKKYE-DNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI-IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYM--SNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+++ C +++G I   +D  +DPC D   + CG   +   +P G SR+++ + I       + ++LE     + S+ + K   FY SCL    R +E R      ++E + G+ ++  +  +N ++ L+    T R   F +V    D  +   N++Q+ +  L L       ++ A  K  + +Y ++M  V ++LG       + +  I+     LA       ++ +  K  N++ ISE+QS      W+D +   +  S   + + + + V+  +Y+  +  ++     ++T   +L   L W ++  +      +   A ++    + G     +  W+TC+S T + L   + S++VK++FD + K   E MI+ I+ A +  +  +TWMD +T+  A  K +AI + IG+PD +L    +  +    + K++E+ F +N ++F  FS   + + + +   +++W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E +  +T+C+++QY  Y +    +   QT+GE+IADN G + AY A+KS+     E   LP + LT +QLFF+G A+ WC++  P +  E +  D H+  K+R+ G  SN  +F++ F C +   MN  K C VW
Sbjct:    9 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLK-EQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGK-VLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFAL--SPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDETGLLYTAKVSEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 683          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETR----PTILEALNGFLLNKKYE-DNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI-IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+++ C +++G I   +D  +DPC D   + CG   +   +P G SR+++ + I       + ++LE     + S+ + K   FY SCL    R +E R      ++E + G+ ++  +  +N ++ L+    T R   F +V    D  +   N++Q+ +  L L       ++ A  K  + +Y ++M  V ++LG       + +  I+     LA       ++ +  K  N++ ISE+QS      W+D +   +  S   + + + + V+  +Y+  +  ++     ++T   +L   L W ++  +      +   A ++    + G     +  W+TC+S T + L   + S++VK++FD + K   E MI+ I+ A +  +  +TWMD +T+  A  K +AI + IG+PD +L    +   Y  +  +E+ F +N ++F  FS   + + + +   +++W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E +  +T+C+++QY  Y +    +   QT+GE+IADN G + AY A+KS+     E   LP + LT +QLFF+G A+ WC++  P +  E +  D H+  K+R+ G  SN  +F++ F C +   MN  K C VW
Sbjct:   60 LCLSEACVSVAGRILDSLDRGIDPCQDFYQYSCGGWMRRNPLPDGRSRWNTFNSIWDQNQAILKHILENATFNSSSEAEMKTQRFYLSCLK-EQRIEELRQKPLTDLIEKIGGWNISGNWRGENFMSVLKTVSGTYRATPFFSVFVSADSKSSNSNIIQVDQSGLFLPSRDYYLNKTANGK-VLDAYLQYMVSVGELLGGSPGSVDMQMTQILEFETLLANLTVPQDERRDEEKIYNRMTISELQSLAPAFDWMDYLTFAL--SPLDLNDTEPVVVYGKEYLQQVSELV-----NNTDPMLLNNYLVWNLVQKMSSSLDSRFEKAQDKLLESLYGAKKSCTPRWQTCLSNTDDTLGFALGSLFVKSTFDKNSKNIAEQMISEIRDAFELTLGGLTWMDEKTRRAAKEKADAIYDMIGFPDFILDTKELDEVYDGV--SEDAFFQNMLNFYNFSAKLMAEQLRKPPNREQWSMTPQTVNAYYLPNKNEIVFPAGILQAPFYAPTHPKALNFGGIGVVMGHELTHAFDDQGREYDEDGNLRPWWQNSSLEAFKNRTECMVNQYNSYTVNGERVNGRQTLGENIADNGGLKAAYHAYKSWLVKHGEEKQLPGVGLTNNQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPAKFRVIGTLSNSKDFAEHFNCPKGTPMNPGKHCDVW 730          

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+ + C +++  I + +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    +  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y+  +  ++     ++T   +L   + W ++        ++  DA  +F  E++  T K+ +  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    PN+ N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C++ QY  Y +    +    T+GE+IADN G + AY A++++   N  E   LP L LT++QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN H KC VW
Sbjct:   70 LGIQYQTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLE-NATASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLRQVSTLI-----NNTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQ-TLPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPHHKCEVW 753          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN----LRNKETRPTILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLW-QNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
             CV + C  ++G+I   +D  V PC D   F CG   +   +P G SR+++ + +       + +LLE     + S+ + K   FY SCL       L  K  R  +++ + G+ +   + ED+ ++ L+    T R   F  V    D  +   N++Q+ +  L L       +  A EK  +T+Y  +M ++  +LG    + +  +  ++ L I+LA        + +  K  +K+ ISE+Q+    + W++ ++ ++  S  ++ + + + V+  +Y+  +  ++     + T+  +L   L W ++        ++   A  +    + G     +  W+TC+S T + L   + S++VKA+FD   K+  E MI  I+ A +  + ++ WMD +T+  A  K +AI + IG+PD +L    + + Y   +++E+ F +N ++   FS   +   + +   +D+W M    VNAYY P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD +G LR WW   S   +   T C+ +QY QY++    L  +QT+GE+IADN G + AY A+K++     E   LP + LT  QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  +F + F C     MN  + C VW
Sbjct:   62 TCVTEACIRVAGKILESLDRGVSPCQDFYQFSCGGWIRRNPLPNGRSRWNTFNSLWDQNQAILKHLLENTTFNSSSEAERKTRSFYLSCLQSERIEKLGAKPLR-DLIDKIGGWNITGPWDEDSFMDVLKAVAGTYRATPFFTVYVSADSKSSNSNIIQVDQSGLFLPSRDYYLNRTANEK-VLTAYLDYMVELGVLLGGQPTSTREQMQQVLELEIQLANITVPQDQRRDEEKIYHKMSISELQALAPAVDWLEFLSFLL--SPLELGDSEPVVVYGTEYLQQVSELI-----NRTEPSILNNYLIWNLVQKTTSSLDQRFETAQEKLLETLYGTKKSCTPRWQTCISNTDDALGFALGSLFVKATFDRQSKEIAEGMINEIRSAFEETLGDLVWMDEKTRLAAKEKADAIYDMIGFPDFILEPKELDDVYDGYEVSEDSFFQNMLNLYNFSAKVMADQLRKPPSRDQWSMTPQTVNAYYLPTKNEIVFPAGILQAPFYAHNHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNESLTAFQNHTACMEEQYSQYQVNGERLNGLQTLGENIADNGGLKAAYNAYKAWLRKHGEEQPLPAVGLTNHQLFFVGFAQVWCSVRTPESSHEGLVTDPHSPARFRVLGTLSNSRDFLRHFGCPVGSPMNPGQLCEVW 734          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEALNGF----------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQ----NEKHI---IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCS------EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLS-ESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYK---IYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C +  C   +  +   +D +V+PC D   + CG   K   IP+  SRY +   +   +   + ++L+ +P         KA   Y+SC+N   ++ R  +    +L  + G+                       LN KY   +L     G   +  +   +       F+  ++G PS    E T       + KE  T+Y  FM  V  ++   Q    +E  +   +  ++ L  ++A       D+++P    NK+ ++++Q+  S        SW +  N +M      ++ ++ + V++ +Y+  L  IL +Y   D     L+  + W  I DLV   S    ++ N F+  + G T ++  W+ C +  +  +   V  +YV+A+F    K  +E +IA I++     ++++TWMD+ETK  A  K  AI  +IGYPD ++S E+ ++N+Y  +   E+++ +N +   KFS ++ L+ + E++ KD+W  G+  VNA+Y+   N+IVFPA  L+ P +     NS NYG IG VIGHEI HGFD +G  ++  G L +WW++ S   +  ++QC++ QYG +         L  I T+GE+IADN G   AY A+++Y   + E  +LP L+L   QLFFL  A+ WC   +P   +  +K DVH+   +RI G   N  EF+ AF C ++  MN  +KC VW
Sbjct:   56 ICKSSDCIKSAARLIQNMDASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQ-EPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIH------FDQPRLGLPSRDYYECT------GIYKEACTAYVDFMISVARLIRQEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEVNGKSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRD-----LQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEALNGF----------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQ----NEKHI---IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCS------EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLS-ESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYK---IYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C +  C   +  +   +D +V+PC D   + CG   K   IP+  SRY +   +   +   + ++L+ +P         KA   Y+SC+N   ++ R  +    +L  + G+                       LN KY   +L     G   +  +   +       F+  ++G PS    E T       + KE  T+Y  FM  V  ++   Q    +E  +   +  ++ L  ++A       D+++P    NK+ ++++Q+  S        SW +  N +M      ++ ++ + V++ +Y+  L  IL +Y   D     L+  + W  I DLV   S    ++ N F+  + G T ++  W+ C +  +  +   V  +YV+A+F    K  +E +IA I++     ++++TWMD+ETK  A  K  AI  +IGYPD ++S E+ ++N+Y  +   E+++ +N +   KFS ++ L+ + E++ KD+W  G+  VNA+Y+   N+IVFPA  L+ P +     NS NYG IG VIGHEI HGFD +G  ++  G L +WW++ S   +  ++QC++ QYG +         L  I T+GE+IADN G   AY A+++Y   + E  +LP L+L   QLFFL  A+ WC   +P   +  +K DVH+   +RI G   N  EF+ AF C ++  MN  +KC VW
Sbjct:   56 ICKSSDCIKSAARLIQNMDASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQ-EPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIH------FDQPRLGLPSRDYYECT------GIYKEACTAYVDFMISVARLIRQEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEVNGKSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRD-----LQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEALNGF----------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQ----NEKHI---IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCS------EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLS-ESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYK---IYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C +  C   +  +   +D +V+PC D   + CG   K   IP+  SRY +   +   +   + ++L+ +P         KA   Y+SC+N   ++ R  +    +L  + G+                       LN KY   +L     G   +  +   +       F+  ++G PS    E T       + KE  T+Y  FM  V  ++   Q    +E  +   +  ++ L  ++A       D+++P    NK+ ++++Q+  S        SW +  N +M      ++ ++ + V++ +Y+  L  IL +Y   D     L+  + W  I DLV   S    ++ N F+  + G T ++  W+ C +  +  +   V  +YV+A+F    K  +E +IA I++     ++++TWMD+ETK  A  K  AI  +IGYPD ++S E+ ++N+Y  +   E+++ +N +   KFS ++ L+ + E++ KD+W  G+  VNA+Y+   N+IVFPA  L+ P +     NS NYG IG VIGHEI HGFD +G  ++  G L +WW++ S   +  ++QC++ QYG +         L  I T+GE+IADN G   AY A+++Y   + E  +LP L+L   QLFFL  A+ WC   +P   +  +K DVH+   +RI G   N  EF+ AF C ++  MN  +KC VW
Sbjct:   56 ICKSSDCIKSAARLIQNMDASVEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVILKDVLQ-EPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLKLLPDIYGWPVASDNWDQTYGTSWTAEKSIAQLNSKYGKKVLINFFVGTDDKNSTQHIIH------FDQPRLGLPSRDYYECT------GIYKEACTAYVDFMISVARLIRQEQSLPIDENQLSLEMNKVMELEKEIANATTKPEDRNDPMLLYNKMTLAKLQNNFSLEVNGKSFSWSNFTNEIMSTVNINIQNEEEVVVYAPEYLTKLKPILTKYSPRD-----LQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMENAVGRLYVEAAFAGESKHVVEDLIAQIREVFIQTLDDLTWMDAETKKKAEEKALAIKERIGYPDDIISNENKLNNEYLELNYREDEYFENIIQNLKFSQSKQLKKLREKVDKDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDGDLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRAYQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIGTLQNSAEFADAFHCRKNSYMNPERKCRVW 750          

Query:  144 FCY*ILFLKDMIWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQN-HSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKYE----------DNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQ-NEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYS-NDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            F + +L L  +  VL   P A  +  A    CV+  C T +  + S++D T DPC D   + CG   +   IP  +S + +  ++E      I N+LE QP+    S+ + KA L+Y SCL++N   +   P     +L  + G+ +   +           + L N    G    + ++   +D  + + +++QI +  L L       +E  ++ + +++Y ++M K+  +LG  + N +  +  ++    +LAK      D+ +  K  N +++ ++Q R   I+W    +  M+   +++ + + + V++ +Y++ L  I++ Y N      +L   L W  +  +    S+   DA+   +  ++G  G  + W+ CV+ T+NV+   + +++V+ +F  + K   E MI  I+ A KS ++ + WMD+ET+  A  K +AI++ IG+PD +L+   +  KY+ +++ E+++ +N +   K++    L+ + + + K +W M    VNAYY P+ N+IVFPA  L+ P YDIG P S NYGA+G V+GHE+ H FD  G +YD  G L +WW+  + E + K+TQC++DQY  Y + N  +   QT+GE+IADN G + AY A+  +   +   L LP LN +  QLFFL  A+ WC+     A+  +++ D H   K+R+ GP SN+ EFS  F+C     MN   KC VW
Sbjct:   16 FSFLLLALLIVSAVLLSRPYAPALLHAEEAYCVSMSCVTAAASVLSLMDATADPCSDFYQYACGGWVRANPIPDTKSMWGTFVKLEQQNQLVIKNVLE-QPMSEFKSEAERKAKLYYMSCLDVNDTIETLGPKPMLDLLVKIGGWNITGNFSIKNWSLQKSLETLQNRYNMG---GLFTWAVGEDDRDSKKHIIQIDQGGLTLPTRDNYLNE-TMDDKVLSAYLEYMTKIGVLLGGEEKNVRTQMKAVIEFETELAKIMSPQEDRRDEEKLYNNMELDKVQGRPPFINWHAFFSNAMENITRKISKKEKVVVYAPEYLEKLNDIIRNYTNTTDGKIILNNYLVWQTVRSMTSYLSKAFRDAYKGLRKALVGSEGGEKPWRYCVTDTNNVIGFAIGAMFVREAFHGNSKPAAENMINQIRTAFKSNLKNLKWMDAETRRAAEKKADAISDMIGFPDYILNPEELDKKYKDLEIKEDEYFENNLRVNKYNLKSNLEKLDQPVNKTRWGMTPPTVNAYYTPTKNQIVFPAGILQAPFYDIGHPKSMNYGAMGVVMGHELTHAFDDQGREYDQNGNLHKWWNNQTIEAFKKRTQCVVDQYSNYTVDNKHVNGKQTLGENIADNGGLKAAYHAYLEWEQRNPRELPLPGLNFSHKQLFFLSFAQVWCSASTDEAIKLQLEKDPHAPPKFRVIGPLSNLQEFSTEFRCPLGSKMNPVHKCEVW 727          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN--LRNKETRPT--ILEALNGF-------------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+N  C   S EI   +D TVDPCDD   + C    K   IP+G+S + +  ++E      I N+LE       S  + KA ++Y+SCL+ +  +     +P   +L  + G+                   +L+ KY  N L    FG A         +D  N   +++QI +  L L      +++    ++ +  Y ++M KV  +LG  +++    +IG ++N   KLA     + D+ N     + +++ ++      ++W D  +  M+  G+++ +D+++ V++ D++  L  I+ + +  +     L   L W  +  L    S+   DA+   +  ++G  G  E+W+ CVS T+NV+   V +I+V+ +F    K   E MIA I++A K  ++ +TW+D +T+  A+ K   I++ IG+PD +L    +  KY  + +T   + +N +    ++    L+ + + + K  W M    VNAYY P+ N+IVFPA  L+ P +DI  P S N+GA+G V+GHE+ H FD  G +YD  G +  WW   S E +++K++CI  QY  YK+   +L   QT+GE+IADN G + AY A++   +D++   L LP LNLT  QLFF+  A+ WC+       L +M+ D H+  ++R+ G  SNM EF++ F+C   K MN  +KC VW
Sbjct:  103 CLNKHCIFASSEILKSIDVTVDPCDDFYGYSCNQWIKNNPIPEGKSTWGTFGKLEQMNQLIIRNVLEKPAKSFKSDAERKAKVYYESCLDADEHMEKLGAKPMNDLLLQIGGWNVTKSGYNVANWTMGHTLKILHNKYNFNCL----FGWAIG-------EDDKNSSRHVIQIDQGGLTLPTADYYNNKTDNHRKVLNEYIEYMTKVCVLLGANESDARAQMIG-VINFEKKLANITIPLEDRRNEEAMYHPMQLRQLSKLAPFLNWTDHFDNAMQMVGRRVTDDEVVVVYAPDFLKNLSDIILKMEQTEEGKITLNNYLVWQAVRTLTSCLSKPFRDAYKGVRKALMGSDGGEEIWRYCVSDTNNVVGFAVGAIFVRQAFHGESKPAAEQMIAEIREAFKMNLQNLTWVDKQTREKAIEKANQISDMIGFPDYILDPVELDKKYAELNITPNAYFENNIQVAIYNLKSNLKRLDQPVNKTNWGMTPQTVNAYYTPTKNQIVFPAGILQTPFFDINNPKSLNFGAMGVVMGHELTHAFDDQGREYDKFGNINRWWDSKSIERFNEKSECIARQYSGYKMNGRTLNGKQTLGENIADNGGLKAAYHAYQRTKSDRDVDILKLPGLNLTHSQLFFVSFAQVWCSSTTDETNLLQMEKDPHSPSQFRVIGTLSNMKEFAEVFQCKPGKRMNPTEKCEVW 786          

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+ + C +++  I + +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    +  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y+  +  ++     ++T   +L   + W ++        ++  DA  +F  E++  T K+ +  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    PN+ N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C++ QY  Y +    +    T+GE+IADN G + AY A++++   N  E   LP L LT++QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN H KC VW
Sbjct:   86 LGIQYQTRTPPVCLTEACVSVTSSILNSMDPTVDPCQDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAVIKHLLE-NATASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIEKLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEDAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLRQVSTLI-----NNTDKCLLNNYMMWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCIPRWKFCVSDTENNLGFALGPMFVKATFAEDSKNIASEIIMEIKKAFEESLSTLKWMDEETRRSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTECMVQQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQ-TLPTLGLTSNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPHHKCEVW 769          

Query:  201 IAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT----ILEALNGFLLNKKY-EDNLLNFLQFGLAT-RMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY--SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            + I  Q+    VC+++ C +++  I S +D TVDPC D  ++ CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   R +E R      ++E L G+ +   + +DN  + LQ   A  R   F +V    D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    E  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I V+  +Y++ +  ++     + T   +L   + W ++        ++  DA  +F  E++  T K+ L  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD ET+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T+C+++QY  Y +    +    T+GE+IADN G + AY A++++   N  E+  LP L LT +QLFFLG A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F+C     MN   KC VW
Sbjct:   87 LGIQYQTRSPSVCLSEACVSVTSSILSSMDPTVDPCHDFFSYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMN-ETRIEELRAKPLMELIERLGGWNITGPWAKDNFQDTLQVVTAHYRTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGDEEAIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVVYDKEYLEQISTLI-----NTTDRCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCLPRWKFCVSDTENNLGFALGPMFVKATFAEDSKSIATEIILEIKKAFEESLSTLKWMDEETRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPKALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQTECMVEQYSNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEH-SLPTLGLTNNQLFFLGFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSLSNSKEFSEHFRCPPGSPMNPPHKCEVW 770          

Query:  204 AILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRP--TILEALNGFLLNKKYE-DNLLNFLQFGLA----TRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE--KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
             I  Q+    VC+++ C +++  I S +D TVDPC D   + CG   K   +P G SR+ + S +  +    I +LLE     + S+ + KA ++Y++C+N   +   + +P   ++E L G+ +   ++ DN  + LQ   +    +   S     D  N   N++Q+ +  L L       ++   EK  +T Y  +M ++  +LG    +  +  +  I++    LA        + +     +K+  +E+Q+    I+W+  +N +      ++ E + I ++  +Y+  +  ++     + T   +L   + W ++        ++  DA  +F  E++  T K+ L  WK CVS T N L   +  ++VKA+F    K     +I  IKKA +  +  + WMD +T+ +A  K +AI N IGYP+ ++    +   +       + + +N + F  FS+      + +   +D+W M    VNAYY+P+ NEIVFPA  L+ P Y    PN+ N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++T C+++QYG Y +    +    T+GE+IADN G + AY A++++   +     LP L LT +QLFFL  A+ WC++  P +  E +  D H+  ++R+ G  SN  EFS+ F C     MN H KC VW
Sbjct:   72 GIQYQTRTPSVCLSEACISVTSSILSSMDPTVDPCQDFFTYACGGWIKANPVPDGHSRWGTFSNLWEHNQAIIKHLLE-NSTASVSEAERKAQVYYRACMNETRIEELKAKPLMELIEKLGGWNITGPWDKDNFQDTLQVVTSHYHTSPFFSVYVSADSKNSNSNVIQVDQSGLGLPSRDYYLNKTENEK-VLTGYLNYMVQLGKLLGGGAEDTIRPQMQQILDFETALANITIPQEKRRDEELIYHKVTAAELQTLAPAINWLPFLNTIFYPV--EINESEPIVIYDKEYLSKVSTLI-----NSTDKCLLNNYMIWNLVRKTSSFLDQRFQDADEKFM-EVMYGTKKTCLPRWKFCVSDTENTLGFALGPMFVKATFAEDSKNIASEIILEIKKAFEESLSTLKWMDEDTRKSAKEKADAIYNMIGYPNFIMDPKELDKVFNDYTAVPDLYFENAMRFFNFSWRVTADQLRKAPNRDQWSMTPPMVNAYYSPTKNEIVFPAGILQAPFYTRSSPNALNFGGIGVVVGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKQQTACMVEQYGNYSVNGEPVNGRHTLGENIADNGGLKAAYRAYQNWVKKNGAEQTLPTLGLTNNQLFFLSFAQVWCSVRTPESSHEGLITDPHSPSRFRVIGSISNSKEFSEHFHCPPGSPMNPHHKCEVW 754          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKE--TRPTI--LEALNGFLLNKKYE------DNLLNFLQ--FGLATRMVSFEAVQDPFNPEFNMLQIGKPSLIL--SEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAW----KSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+ + C T++  I + +D + DPC D   + CG   K   IP G+S + +  ++E +    + N+LE    +  S+ + KA  +Y+SC++ N   +E   +P +  LE + G+ ++ K++       N ++ LQ  + +   + S+   +D  N   +++QI +  L L  ++  L  +E     + + +Y  +M K+  +LG  +N  K  + ++++   KLA+      ++ +  K  N + +S++Q R   +SW+D      +   K++    +I  F+ +Y   L  ++++Y        +L   L W  +  L    S+   DA+   +  +LG  G  E W+ CVS  +N +   + +++V+  F    K   E MI  ++KA    ++ + WMD+ET+  A  K  AIT+ IG+PD +L  S +  +YR + + + ++ +N +   K++  + L+   +++ K  W M    VNAYY P+ N+IVFPA  L+ P YD+  PNS N+G IG V+GHE+ H FD  G +YD  G L +WW+ ++ E +  +T+C ++QY QY++    +   QT+GE+IADN G + AY A+    KSY   K+ L LP LNLT  QLFFL  A+ WC+ +   A+  +++ D H+  KYR+NGP SN+PEF+  F C +D  MN   KC VW
Sbjct:   99 CLTEHCVTVAASIINSIDYSADPCGDFYEYACGGWRKKNPIPDGKSVWGTFGKLEQDNQLVVKNVLEKPFSEMKSKAEKKAKYYYQSCMDANETIEELGAKPMLELLEIIGGWNVSGKFDVNTWSLQNSMHILQNVYNMGG-LFSWAVNEDDRNSSRHIIQIDQGGLTLPTADNYLNVTEHG---KVLAAYLDYMTKIGVLLGGEENSTKRQMQDVIDFETKLAEITTPPDERRDEEKLYNLMSLSDLQRRAPFMSWVDYFQNATRLVNKKVNSKVMIVNFAPEYFVKLTKLVQQYNKTTNGKIILNNYLVWQTVRSLTACLSKPFRDAYKGLRKALLGSEGHEEQWRYCVSDVNNAMGFAIGAMFVREVFHGKSKPMAEEMIDQVRKAFTKNLKNLDWMDAETRKAAEEKANAITDMIGFPDFILQPSALDERYRDLVIKQYEYFQNNLRVNKYNLKKNLEKFEQEVNKTTWIMTPPTVNAYYTPTKNQIVFPAGILQSPFYDMENPNSLNFGGIGVVMGHELTHAFDDQGREYDLHGNLHQWWNDATIERFKNRTECFVEQYSQYQVQGRHVNGRQTLGENIADNGGLKAAYHAYLSMPKSY---KDQLPLPGLNLTHRQLFFLNFAQVWCSAITSEAVTLQIEKDSHSPPKYRVNGPLSNLPEFAMEFNCPKDSKMNPGHKCEVW 779          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKE--TRPTI--LEALNGFLLNKKYE------DNLLNFLQ--FGLATRMVSFEAVQDPFNPEFNMLQIGKPSLIL--SEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAW----KSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+ + C T++  I + +D + DPC D   + CG   K   IP G+S + +  ++E +    + N+LE    +  S+ + KA  +Y+SC++ N   +E   +P +  LE + G+ ++ K++       N ++ LQ  + +   + S+   +D  N   +++QI +  L L  ++  L  +E     + + +Y  +M K+  +LG  +N  K  + ++++   KLA+      ++ +  K  N + +S++Q R   +SW+D      +   K++    +I  F+ +Y   L  ++++Y        +L   L W  +  L    S+   DA+   +  +LG  G  E W+ CVS  +N +   + +++V+  F    K   E MI  ++KA    ++ + WMD+ET+  A  K  AIT+ IG+PD +L  S +  +YR + + + ++ +N +   K++  + L+   +++ K  W M    VNAYY P+ N+IVFPA  L+ P YD+  PNS N+G IG V+GHE+ H FD  G +YD  G L +WW+ ++ E +  +T+C ++QY QY++    +   QT+GE+IADN G + AY A+    KSY   K+ L LP LNLT  QLFFL  A+ WC+ +   A+  +++ D H+  KYR+NGP SN+PEF+  F C +D  MN   KC VW
Sbjct:   95 CLTEHCVTVAASIINSIDYSADPCGDFYEYACGGWRKKNPIPDGKSVWGTFGKLEQDNQLVVKNVLEKPFSEMKSKAEKKAKYYYQSCMDANETIEELGAKPMLELLEIIGGWNVSGKFDVNTWSLQNSMHILQNVYNMGG-LFSWAVNEDDRNSSRHIIQIDQGGLTLPTADNYLNVTEHG---KVLAAYLDYMTKIGVLLGGEENSTKRQMQDVIDFETKLAEITTPPDERRDEEKLYNLMSLSDLQRRAPFMSWVDYFQNATRLVNKKVNSKVMIVNFAPEYFVKLTKLVQQYNKTTNGKIILNNYLVWQTVRSLTACLSKPFRDAYKGLRKALLGSEGHEEQWRYCVSDVNNAMGFAIGAMFVREVFHGKSKPMAEEMIDQVRKAFTKNLKNLDWMDAETRKAAEEKANAITDMIGFPDFILQPSALDERYRDLVIKQYEYFQNNLRVNKYNLKKNLEKFEQEVNKTTWIMTPPTVNAYYTPTKNQIVFPAGILQSPFYDMENPNSLNFGGIGVVMGHELTHAFDDQGREYDLHGNLHQWWNDATIERFKNRTECFVEQYSQYQVQGRHVNGRQTLGENIADNGGLKAAYHAYLSMPKSY---KDQLPLPGLNLTHRQLFFLNFAQVWCSAITSEAVTLQIEKDSHSPPKYRVNGPLSNLPEFAMEFNCPKDSKMNPGHKCEVW 775          

Query:  186 LKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQN-HSQHQTKAALFYKSCLNLN--LRNKETRPTI--LEALNGFLLNKKYED---NLLNFLQFGLATR-----MVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQIT-SYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            L FL +    Q      C+ + C T +  + S +D +VDPCDD   F CGN  KV  IP G+S + +  +++      + N LE +P Q   S+ + KA L+Y SC++ N  + +   +P +  L+ + G+ ++  ++    NL   LQ  L  R     + S+   +D  N   +++Q+ +  L L   T  +  +A   E+I  +Y ++M ++  +LG  +N  K ++ ++++   +LA+      ++ +  K  N + ++E+Q     I+W    +  ++   K++ + + + V++ +Y+  L  +L EY N       +   L W  +  +    S    DA+   +  ++G  G  E W+ CV+ T+NVL   + ++YV+  F    K   + MI  ++ A K  ++E+ WMD ET+  A  K +AIT+ IG+PD +L    +  KY+ ++++E ++ +N ++  +++  Q L+ +G+ + + +W+M    VNAYY P+ N+I FPA  L+ P YD+    + N+GA+G V+GHE+ H FD  G +YD  G + +WW+  + E + ++ +C+++QY  Y++ N  +   QT+GE+IADN G + AY A+  + + +KE L LP +NLT  QLFFL  A+ WC+     A   +++ D H   K+R+ G  SN PEF++ F C     MN  KKC+VW
Sbjct:   80 LHFLHVNTRPQE--ETYCLTETCVTTAASLVSSIDRSVDPCDDFYQFACGNWIKVNPIPDGKSMWGTFVKLDQQNQLVMKNALE-KPFQELKSKAEKKAKLYYMSCMDSNETIESLGAKPMLDLLKEVGGWSVDDNFDIEKWNLQTTLQL-LQNRYNMGGLFSWAVQEDDRNSSLHIIQVDQGGLTLP--TRDTYLNATANEKILHAYLEYMTEIGVLLGGERNRTKSLMKDVIDFETRLAQITIPADERRDEEKMYNLMAVAELQDLAPFINWEKYFSDALRLVRKKITDKEKVVVYAPNYLANLTTVLNEYMNTSEGNITINNYLVWQTVRSMTACLSRPFRDAYKGLKKALIGTEGGEESWRYCVTDTNNVLGFALGAMYVREVFQGKSKAQAQQMINAVRTAFKENLKELKWMDKETRELAEAKADAITDMIGFPDYILDPKQLDEKYKELEVSEHQYFQNNINANQYNLKQNLRKLGQPVNRTRWNMTPSTVNAYYTPNRNQIAFPAGILQAPFYDVRHQQALNFGAMGVVMGHELTHAFDDQGREYDKYGNMHQWWNNKTIERFKEQAECVVNQYSSYQMNNKRINGKQTLGENIADNGGLKAAYRAFIDWAAKNKEELPLPAVNLTHKQLFFLSFAQVWCSASTEEATNLQVEKDTHATPKFRVIGSLSNSPEFAENFNCREGSKMNPKKKCVVW 775          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNH-SQHQTKAALFYKSCLNLN--LRNKETRPTI--LEALNGFLLNKKYEDNLLNFLQFGLATRMVSFE-----------AV-QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+N+ C   S +I + +D +V+PCDD   + C    K   IP G+S + + S IE      I N+LE +P+++  S+ + KA ++Y+SCL+ N  L     +P +  L  + G+ ++        N  Q+ LA  + + +           A+ +D  N   +++QI +  L L       +   + ++ +  Y ++M KV  +LG  + + +  +  +++   K+A     + ++ N     + +K+SE+      I+W + ++  M+  G+++ + +++ V++ +++  L  I+ E +        L   L W  +  L P  S    DA+   +  ++G  G  E+W+ CV+ T NV+   V +I+V+ +F    K + E MI  I++A K  IE ++WMD+ T+A A+ K +AI++ IG+PD +L+++ +  KY  + +T + + +N +    F+  + L+ + + + K  W M    VNAYY PS N+IVFPA  L+ P +D   P S N+GA+G V+GHE+ H FD  G ++D  G +  WW   S + +++KT+CI  QYG Y I    L   QT+GE+IADN G + AY A+   S DKE   L LP LNLT  QLFF+  A+ WC+      ++ +++ D H+  + R+ G  SNMPEF++ F+C     MN  KKC VW
Sbjct:  100 CLNEHCIFASNDILNSIDRSVNPCDDFYGYACNQWVKNNPIPDGKSSWGTFSNIEQRNQLIIKNILE-RPMKSFTSEAEKKAKIYYESCLDRNDQLEKLGAKPMVSFLWKIGGWNVSH----TGFNMGQWSLAKTLKTLQNRYNINCLFGWAIGEDDKNSTRHIIQIDQGGLTLPTPEYYENRTEIHRKVLKEYIEYMTKVCVLLGANETDARRQMQEVMDFETKIANITIPLEERRNEEAMYHPMKLSELDKLAPFINWTEHLDHAMELVGRRVTQREVVVVYAPEFLKKLAVIIAEMEKTVEGRNTLNNYLVWQAVRVLTPCLSRSFRDAYKGVRKALMGSDGGEEVWRFCVADTGNVVGFAVGAIFVRQAFHGDSKPEAEQMINEIREAFKVSIENLSWMDNRTRARAIEKADAISDMIGFPDYILNQAELDKKYADLNVTADAYFENNIQSNIFNLKKNLEKLDQPVNKTNWGMVPHMVNAYYTPSKNQIVFPAGILQSPFFDRHHPKSLNFGAMGVVMGHELTHAFDDQGREFDKYGNINRWWDNKSIDRFNEKTECIEKQYGSYAISGRHLNGKQTLGENIADNGGLKAAYHAFLKTSMDKEADVLKLPGLNLTHKQLFFVSFARVWCSSDTEETIMLQLEKDTHSPSRLRVIGTLSNMPEFAEVFQCKPGSKMNPDKKCAVW 783          

Query:  237 CVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNH-SQHQTKAALFYKSCLNLN--LRNKETRPTI--LEALNGFLLNKKYEDNLLNFLQFGLATRMVSFE-----------AV-QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            C+N+ C   S +I + +D +V+PCDD   + C    K   IP G+S + + S IE      I N+LE +P+++  S+ + KA ++Y+SCL+ N  L     +P +  L  + G+ ++        N  Q+ LA  + + +           A+ +D  N   +++QI +  L L       +   + ++ +  Y ++M KV  +LG  + + +  +  +++   K+A     + ++ N     + +K+SE+      I+W + ++  M+  G+++ + +++ V++ +++  L  I+ E +        L   L W  +  L P  S    DA+   +  ++G  G  E+W+ CV+ T NV+   V +I+V+ +F    K + E MI  I++A K  IE ++WMD+ T+A A+ K +AI++ IG+PD +L+++ +  KY  + +T + + +N +    F+  + L+ + + + K  W M    VNAYY PS N+IVFPA  L+ P +D   P S N+GA+G V+GHE+ H FD  G ++D  G +  WW   S + +++KT+CI  QYG Y I    L   QT+GE+IADN G + AY A+   S DKE   L LP LNLT  QLFF+  A+ WC+      ++ +++ D H+  + R+ G  SNMPEF++ F+C     MN  KKC VW
Sbjct:   96 CLNEHCIFASNDILNSIDRSVNPCDDFYGYACNQWVKNNPIPDGKSSWGTFSNIEQRNQLIIKNILE-RPMKSFTSEAEKKAKIYYESCLDRNDQLEKLGAKPMVSFLWKIGGWNVSH----TGFNMGQWSLAKTLKTLQNRYNINCLFGWAIGEDDKNSTRHIIQIDQGGLTLPTPEYYENRTEIHRKVLKEYIEYMTKVCVLLGANETDARRQMQEVMDFETKIANITIPLEERRNEEAMYHPMKLSELDKLAPFINWTEHLDHAMELVGRRVTQREVVVVYAPEFLKKLAVIIAEMEKTVEGRNTLNNYLVWQAVRVLTPCLSRSFRDAYKGVRKALMGSDGGEEVWRFCVADTGNVVGFAVGAIFVRQAFHGDSKPEAEQMINEIREAFKVSIENLSWMDNRTRARAIEKADAISDMIGFPDYILNQAELDKKYADLNVTADAYFENNIQSNIFNLKKNLEKLDQPVNKTNWGMVPHMVNAYYTPSKNQIVFPAGILQSPFFDRHHPKSLNFGAMGVVMGHELTHAFDDQGREFDKYGNINRWWDNKSIDRFNEKTECIEKQYGSYAISGRHLNGKQTLGENIADNGGLKAAYHAFLKTSMDKEADVLKLPGLNLTHKQLFFVSFARVWCSSDTEETIMLQLEKDTHSPSRLRVIGTLSNMPEFAEVFQCKPGSKMNPDKKCAVW 779          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRPTI--LEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAVQ---DPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQ---ITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+ + C T++ +I   +D TVDPC D   + CG   +   +P G SR+ + + I       + +LLE     + S+ + KA  +Y SCLN   +     +P +  +    G+ + + ++ DN ++ L+      R   F  V    DP N   N++Q+ +  L L      S +  L K     + +Y  +M ++  +LG  +N  ++ +  I++    LA       ++ +  K  +K+ I+E+Q+    + W+D ++ V+  S  ++ + + + V++ +Y+  +  ++ +     T   +L   + W ++        ++  +A ++    + G     +  W+TC+  T + L   + +++V A+FD   K+  E MI  I+ A +  ++ + WMD +T+  A  K + I + IGYPD +L    + + Y    ++E+ F +N ++F  FS   +   + +   KD+W M    VNAYY P+ N IVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS + +  +T+C++DQY QY I    +   QT+GE+IADN G + AY A++S+   + E   LP +NLT DQLFF+G A+ WC++  P +  E +  D H+  KYR+ G  SN P+FS+ F C     MN   +C VW
Sbjct:   92 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLP-----SRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELINK-----TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 763          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRPTI--LEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAVQ---DPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQ---ITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+ + C T++ +I   +D TVDPC D   + CG   +   +P G SR+ + + I       + +LLE     + S+ + KA  +Y SCLN   +     +P +  +    G+ + + ++ DN ++ L+      R   F  V    DP N   N++Q+ +  L L      S +  L K     + +Y  +M ++  +LG  +N  ++ +  I++    LA       ++ +  K  +K+ I+E+Q+    + W+D ++ V+  S  ++ + + + V++ +Y+  +  ++ +     T   +L   + W ++        ++  +A ++    + G     +  W+TC+  T + L   + +++V A+FD   K+  E MI  I+ A +  ++ + WMD +T+  A  K + I + IGYPD +L    + + Y    ++E+ F +N ++F  FS   +   + +   KD+W M    VNAYY P+ N IVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS + +  +T+C++DQY QY I    +   QT+GE+IADN G + AY A++S+   + E   LP +NLT DQLFF+G A+ WC++  P +  E +  D H+  KYR+ G  SN P+FS+ F C     MN   +C VW
Sbjct:   94 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLP-----SRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELINK-----TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 765          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRPTI--LEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAVQ---DPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQ---ITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGK-SELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+ + C T++ +I   +D TVDPC D   + CG   +   +P G SR+ + + I       + +LLE     + S+ + KA  +Y SCLN   +     +P +  +    G+ + + ++ DN ++ L+      R   F  V    DP N   N++Q+ +  L L      S +  L K     + +Y  +M ++  +LG  +N  ++ +  I++    LA       ++ +  K  +K+ I+E+Q+    + W+D ++ V+  S  ++ + + + V++ +Y+  +  ++ +     T   +L   + W ++        ++  +A ++    + G     +  W+TC+  T + L   + +++V A+FD   K+  E MI  I+ A +  ++ + WMD +T+  A  K + I + IGYPD +L    + + Y    ++E+ F +N ++F  FS   +   + +   KD+W M    VNAYY P+ N IVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS + +  +T+C++DQY QY I    +   QT+GE+IADN G + AY A++S+   + E   LP +NLT DQLFF+G A+ WC++  P +  E +  D H+  KYR+ G  SN P+FS+ F C     MN   +C VW
Sbjct:  115 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLP-----SRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELINK-----TDRNLLNNYMIWNLVQKGASSLDQRFENAQDKLLESLYGTKKSCTPRWQTCIGNTDDTLGFALGALFVNATFDKHSKEIAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 786          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN-LNLRNKETRPTI--LEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAVQ---DPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQ---ITSYTKFMNKVLDILGLWQNE-KHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+ + C T++ +I   +D TVDPC D   + CG   +   +P G SR+ + + I       + +LLE     + S+ + KA  +Y SCLN   +     +P +  +    G+ + + ++ DN ++ L+      R   F  V    DP N   N++Q+ +  L L      S +  L K     + +Y  +M ++  +LG  +N  ++ +  I++    LA       ++ +  K  +K+ I+E+Q+    + W+D ++ V+  S  ++ + + + V++ +Y+  +  ++ +     T   +L   + W    +LV  G+  L       Q ++L                         S+Y          K  E MI  I+ A +  ++ + WMD +T+  A  K + I + IGYPD +L    + + Y    ++E+ F +N ++F  FS   +   + +   KD+W M    VNAYY P+ N IVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS + +  +T+C++DQY QY I    +   QT+GE+IADN G + AY A++S+   + E   LP +NLT DQLFF+G A+ WC++  P +  E +  D H+  KYR+ G  SN P+FS+ F C     MN   +C VW
Sbjct:   94 LCLTEACVTVASKIVESLDRTVDPCQDFYQYACGGWIRKNPLPDGRSRWSTFNSIWDQNQAVLKHLLENGTFNSSSEAEKKAQFYYLSCLNEQRIEELGAQPLVDLIAKTGGWNITETWDKDNFMDVLKTVSGPYRAQPFFTVGVSVDPKNSNSNVIQVDQSGLFLP-----SRDYYLNKTNEKVLKAYLDYMVELGLLLGGDKNSTQNQMQQILDFETALANITVPQDERRDEEKIYHKITIAELQTLAPAVEWLDYLSSVL--SPLELNDTEPVVVYAKEYLQQVSELINK-----TDRNLLNNYMIW----NLVQKGASSLDQRFENAQDKLL------------------------ESLY--------GTKKAEGMINEIRTAFQDALDHLNWMDDQTRKAAKEKADDIYDMIGYPDFILDPKELDDVYDGYDVSEDNFFQNMLNFYNFSARVMADQLRKPPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYARDHPKALNFGGIGVVMGHELTHAFDDQGREYDKTGNLRPWWQNSSVDAFKNRTECMVDQYTQYTINGEHINGKQTLGENIADNGGLKAAYHAYRSWVKTNGEEKSLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPKYRVIGTLSNSPDFSQHFNCPLGSPMNSGHRCEVW 728          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALN---GFLLNK-----------KYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVL----DILGLWQNEKHIIGN---IVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCS--EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSES--YMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYK---IYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            VC    C T +  +   +D  V+PC +   + CG     + IP+  SRY     +   + + +  +LE +        + KA + Y SC+N NL  K     +L+ ++   G+ +               ED L  F        ++      D  + + ++L + +P L L       S++   K    +Y +FM  V+    +   L  NE  +  +   +++L + +A       D+ +     NK+ +S++  + S    +W   + GV+       + D+ + V+   Y+  L  +L  Y N     + L+  L W ++ D V   S +  DA  Q++  +   T     W+ CV    N +   V ++YVK +F    K+ +  +I+ I+ A    +EE++WMD ++K  A  K  AI ++IGYPD +L E    +  +Y  I  +++ + +N +     +  + L+ + E +  D W +G+  VNA+Y+P+ N+IVFPAA L+ P Y      + N+G IG VIGHEI HGFD +G  +D  G +  WWS  S E +  ++QC++ QYG +         +  + T+GE+IADN G R AY A+K +   + E   LP LNL  DQLFFL   + WC   +       ++ D H+   YR+ G   N   FS+AF C     MN   KC VW
Sbjct:   63 VCTTPACVTAAARLLQNMDQDVEPCQNFYRYACGGWLDRHVIPETSSRYSVFDILRDELESILKGVLENEKELGREAFR-KAKVLYASCMNENLIEKRGAQPLLDLIDYVGGWPVASDEWNVTEDNEWSLEDTLAMFNSHFHKRVLLDLFVWTDDLDSKQHILYLDQPMLGLPTRDYYFSDEGDYKTVREAYLQFMISVMLMTREARNLTSNETIVREDALQVMHLEMDIANVTIPAQDRLDVTSLYNKMALSDLHRKFSLNGFNWTRFVLGVLSEVSITAQPDENVVVYCDQYLQKLGEVLARYNN-----RTLRNYLIWHLVIDRVSSLSSRFKDARAQYKKALYRNTMVEARWRDCVRYVQNTMENAVGALYVKQTFAGESKRMVRELISRIQGAFVETLEELSWMDDQSKKMARQKAMAIKDQIGYPDFILEEENDKLDLEYEQINFSKKTYFENMLKNLHAAAQKSLKNLREPVDTDFWMIGAAVVNAFYSPNRNQIVFPAAILQPPFYSKDQLQALNFGGIGMVIGHEITHGFDDNGRNFDKDGNMLNWWSNFSAEHFRAQSQCMVQQYGNFTWDLAGGQKVCGVSTLGENIADNGGVRQAYKAYKKWRETEGEEPYLPGLNLNNDQLFFLNFGQVWCGTYRAEYASHSIRTDSHSPLDYRVLGSLQNFDAFSEAFHCKPGSPMNPPVKCRVW 755          

Query:  189 KFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEALNGFLL-------NKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI----------IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCS--EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLL--SESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYK---IYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDK-ENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            ++LP       + S  C+ +    L+  I   +D + DPC D   + CG   K   IP+  SRY     +   +   +  +LE         ++ K+   Y SC++   +   N +    +L  +N + +        ++Y+ NL N  +      +V+     D  N    ++ I +P   L       SE     +   +Y  F+  + +I+   + +K I          +  + N   KLA+      ++++     +K+ +SE+ +  S    SW+  +  +     K +   + I V++ +Y+  L  IL     +D     ++  + W +  + V   S++  DA  +F+  + G T     W++C S  +N+LS  V ++YV+ +F    KK ++ ++  I++   S ++++TWMD  TK  A  K  AI  +IGYP+ ++  ++  +  +Y  +  +  ++  N +    F   + L  +   + K++W  G+  VNA+Y+ S N+IVFPA  L+ P + +    S N+G IG VIGHEI+HGFD  G  +D  G L +WWS  S + + +K+QCIIDQYG ++       +L  I T+GE+IADN G R AY A+ ++  D  E L LP L+L+  QLFFL  A+ WC   +P      +K DVH+  K+R+ G   N  +FS+A++C     MN   KC VW
Sbjct:    5 RWLPTLWAALRSGSACCLLNNLVFLAARILENMDPSADPCKDFYKYACGGWLKKNIIPETSSRYGVFDILRDELEVVLKAVLEKSDDAARDAYK-KSRTLYASCIDQEKIEALNSQPLLQLLGNVNEWPIATVNWNTTQEYQKNLANLAKKYRVRPIVNTYVGIDDKNSTAYIINIDQPGFGLPSRDYYFSETESYVKAREAYKDFIVAIANIV---RRDKAIPDDDVFVREQMEGLFNFEKKLAEASTPDENRTDITLIYHKMSLSELSTNYSIGNFSWLTYMKDIFIDI-KDISSAENIVVYAPEYLIKLKTIL-----EDETPSTIQNYIVWMLTVEHVESLSQKFKDARAEFRKALYGTTSDKARWRSCSSYVNNILSNAVGALYVEEAFAGDSKKVVQELVKWIREVFISNLDKITWMDDATKGRARDKAFAIVERIGYPEFIVDKNDPKIDEEYADLAYSTTEYFANTLASLAFDSKRRLARINTAVDKNEWISGAAVVNAFYSSSYNQIVFPAGILQPPFFGLDQAMSLNFGGIGMVIGHEIIHGFDDSGRNFDKDGNLVDWWSAESAKNFKQKSQCIIDQYGNFQWDLAGGQNLSGINTLGENIADNGGIRQAYEAYMAWVKDNGEELPLPGLHLSHQQLFFLNFAQVWCGDYRPEYASNSIKTDVHSPGKFRVIGSLQNFEKFSEAYQCKASDAMNPRSKCHVW 707          

Query:  684 IGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIAD--QSNPNKYTNKLKISEIQSRCS---EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLN---LTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKY---RINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            I +  L L E +L   +D    + I +Y   MNK+  +LG  +N +H + ++     +LA    S +D  + + N   NK+K+ ++        +I+W   +  + +   K++ ED+ + V +  YI  L  +L       T ++VL   + W V+  L    S     A + F  E+ G   + +L + C++  +     ++ +++V+  F    K+ ++ M+ +IK A    +EE+ WMD +TK  A  K + + + IGYP+ L     +  +Y   ++ E+ + KN ++  +F+ N  +  + +++ ++ W +    +NAYY P+ N++VFPA  L+   YD   P S NYG IG++IGHE+ HG+D  G +YD  G L++WW+  S  ++ ++T+C++  Y  + I   ++    T+GE+IAD  G ++AY A++ +   +EN   P L     T +QLFF+  A+ WC   +P +L  ++  D H+   Y   R+ G  S   EF + F C R   M+   KC VW
Sbjct:    1 IDQEGLTLPERSLYLGQDEESLKVIKAYKVLMNKITTLLGA-RNARHKLEDVFEFEQQLANITLSESDPLRRDINNMYNKMKLRDLHHLAPAHDQINWRQFLEQIFR---KRISEDEEVVVLATTYIKKLSHLL-----STTPVRVLHNYMLWRVVIVLSTHLSPPFRAALHDFSREVDGAEKEVDLERLCLAQANKYFGMVLGALFVREHFSLHSKQRVQQMVEDIKHAFDQRLEELGWMDEKTKDAARGKFQLMMDMIGYPEFLGRMDEVDKEY-GFEVNEKSYFKNILNSIEFNINVSIHKIHQKVERNVWLLPPQTLNAYYLPTHNQMVFPAGILQPTLYDPEFPQSMNYGGIGTIIGHELTHGYDDWGGQYDRHGNLKQWWTAESYGKFLERTECVVKLYNNFTINKQNVNGKLTLGENIADMGGLKLAYHAYQKWV--RENGPEPPLQGMAYTHEQLFFVAFAQNWCMKRRPQSLYLQLLTDKHSPENYSRRRVLGSASQFDEFGRVFHCRRGSPMSPQHKCSVW 519          

Query:  285 VDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEAL----------NGFLLNKKYEDNLLNFLQFGLATR-MVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNI----------VNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSR--CSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLL--SESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQY 1892
            ++   +PCD+   F CG   K   IP+    Y +   ++ ++   +  LLE           TKA   Y SC++   +  R+ E    +LE +          N    ++   + +L F+      R ++      D  + + + + I +PSL L        +    + + T Y + M  V  I+   + +K+I  +I            L +++A+      ++++  K  N++ + ++Q     +  +W   IN V+K    +++  + I V + +Y++ L  IL  +   D    V+     W +I +++   S +  +A  + Q  + GV      W+ CV   +  L   V ++YV  +F    K  +E+MI  +++A    ++E+TWMD  T+A A  K  AIT ++GY D ++  +   +  +Y  +   E+   +N +   +F+    L+ +     K +WD+G   +NA+Y+PS N+IVFPA  L+ P + +G   S N+G IG VIGHEI HGFD  G K+D +G L +WW+  S E++  +++C++ QY  Y
Sbjct:    8 MNPAANPCDNFYEFACGGWPKKQVIPEDSGYYGTFHVLDDHLEIVLKRLLEEAAGSGDRDAVTKAKRLYLSCMDEEAIEERDSEPLLWLLEDVLEWPVATVDWNSTYGSQWRLEEVLAFMTSRYGNRVIIDVGIASDVNDSKSSAIYIDQPSLGLPTRDFYFDKGYYSQVRDT-YLRAMIAVATII---RADKNITDDIDFVQEQMEGVFRLEMEIAEAITPAENRTDVTKLFNRMTLLQLQQEFPLNGFNWTLFINEVLKTVDIEVEASEEILVSAPEYLEQLSDILNSHPPSDVHNYVV-----WILITEVIGSLSHKYQEAIAETQKMLYGVLLARARWRHCVDYVNTALPSAVGALYVLDAFPRHGKTKVEMMIERLREAFIHTLDEMTWMDDRTRARAREKALAITTQMGYADYIVDGNNPRLDEEYADLNYEEDVHFENTLQDLEFAVKNELKRLRRTTSKQEWDIGPATINAFYHPSKNQIVFPAGILQPPFFGLGQAMSLNFGGIGMVIGHEITHGFDNFGRKFDKEGNLVDWWTAESDEDFDSRSRCLVSQYSSY 562          

Query:  285 VDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLN---LNLRNKETRPTILEAL----------NGFLLNKKYEDNLLNFLQFGLATR-MVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNI----------VNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQS-------RCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLL--SESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQY 1892
            ++   +PCD+   F CG   K   IP+    Y +   ++ ++   +  LLE           TKA   Y SC++   +  R+ E    +LE +          N    ++   + +L F+      R ++      D  + + + + I +PSL L        +    + + T Y + M  V  I+   + +K+I  +I            L +++A+      ++++  K  N++ + ++Q        R    +W   IN V+K    +++  + I V + +Y++ L  IL  +   D    V+     W +I +++   S +  +A  + Q  + GV      W+ CV   +  L   V ++YV  +F    K  +E+MI  +++A    ++E+TWMD  T+A A  K  AIT ++GY D ++  +   +  +Y  +   E+   +N +   +F+    L+ +     K +WD+G   +NA+Y+PS N+IVFPA  L+ P + +G   S N+G IG VIGHEI HGFD  G K+D +G L +WW+  S E++  +++C++ QY  Y
Sbjct:    8 MNPAANPCDNFYEFACGGWPKKQVIPEDSGYYGTFHVLDDHLEIVLKRLLEEAAGSGDRDAVTKAKRLYLSCMDEEAIEERDSEPLLWLLEDVLEWPVATVDWNSTYGSQWRLEEVLAFMTSRYGNRVIIDVGIASDVNDSKSSAIYIDQPSLGLPTRDFYFDKGYYSQVRDT-YLRAMIAVATII---RADKNITDDIDFVQEQMEGVFRLEMEIAEAITPAENRTDVTKLFNRMTLLQLQQEFPLNKLREQGFNWTLFINEVLKTVDIEVEASEEILVSAPEYLEQLSDILNSHPPSDVHNYVV-----WILITEVIGSLSHKYQEAIAETQKMLYGVLLARARWRHCVDYVNTALPSAVGALYVLDAFPRHGKTKVEMMIERLREAFIHTLDEMTWMDDRTRARAREKALAITTQMGYADYIVDGNNPRLDEEYADLNYEEDVHFENTLQDLEFAVKNELKRLRRTTSKQEWDIGPATINAFYHPSKNQIVFPAGILQPPFFGLGQAMSLNFGGIGMVIGHEITHGFDNFGRKFDKEGNLVDWWTAESDEDFDSRSRCLVSQYSSY 567          

Query: 1125 WAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSEL--WKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNA-YYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTD-GSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTR---MAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPN--ALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKC 2198
            W +I  ++P+   +   A     +E +  T +S +  W+ C+ +    L+  +  I+        +K+D++ MI N+K A K  ++ + WMD++T+  A  K + I + +G  D +   S +   Y + K+ E +F +  V+F  ++  + ++++       +W   +  V+A YY  S N +  PA  ++ P Y    P    Y  IG+VIGHE+ HGFD   GS+Y+ +G    WW  ++  E+  +T C+  QY  Y      +   QT+GE+IADN G     +AY  W+     +E   LP LNLT  Q FF+  A+ WC++ K +    +E    D H+    R+ G  SN P F++AF C
Sbjct:   57 WMLIQKMIPILDYRFRKA-ALIMAEAIDETTESPVRRWEFCMDLADKSLAYALGEIFAMKEITAKRKEDVKKMIDNLKHAFKDNLDHLPWMDNKTRLAAKEKAKNIQSAVGEDDYMEDVSNVDMFYENFKVVEGRFFETMVNFYNYTSRRTIRSM--LATSMQWRAPAQTVDAFYYYESLNTMYIPAGIMQEPFYQDVYPMFLKYAGIGTVIGHELCHGFDNKAGSEYNVEGKQENWWENTTHNEFKLRTHCMEVQYSNYTWKERPINGTQTLGENIADNGGLHTALLAYARWEEQHGKEE--PLPYLNLTNKQAFFVWFAQLWCSMEKESVEVEIEDALSDSHSPAAVRVRGMVSNSPAFAEAFTC 418          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLE----IQPLQNHSQHQTKAALFYKSCLNL-NLRNKETRP--TILEALNGFLL------NKKYED--NLLNFLQ--FGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKG-MLREWWSKSSREEYSKKTQCIIDQYGQYKIYN-VSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN--LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            VC    C+ ++  I+  +DT   PC D   F CGN  + + IP+  + + + +++  ++ +++  LLE    I+ L   +Q   KA  FY+SC++   +    TRP   ++  L  + L      NK+  D  ++L  LQ  +  A+   S E   D  N   +++++ +  L     +LQ        E + +Y ++M KV  +LG+  N    +  IV+   KLA    S  D+++      ++K+  +        W+  +  + +G+   + + D++      Y+  +  I+KE     T  ++L   + W +I D + L S+    A   F  +I GV  +   W+TC S+T++ L   + ++YV+  F+ S    I+LMI  IK   K  ++E  W+D +T      K +A+ +KIGY + +L    +  +++S+K+ ++ F  N V+  K+  ++L+  + + + K+KW M    +NA Y    NEI      LR     + L  S +YGA+GS+IGHE+ HGFD  G K+D  G +++EWWSKSS   +  + QCI DQY ++KI N   L  + T+ E+IADN GT+++Y A+  +  D  N   VLP L  T +QLFF+G A+ +C+  +P         D+H+  K+R+ G  SNM EFS AFKC     MN  KKC VW
Sbjct:    1 VCQEPECQQIATLIRDAIDTDTPPCKDFFKFSCGNWVRKHPIPRSYNDFSTFTKVSKDIEDQLRELLETPSYIETLP-ENQALRKAKDFYRSCMDTKTIERLGTRPLMKLIRQLGSWSLCNDKSWNKEKWDAYDVLRKLQSTYYPASPFFSVEVTNDHLNSTRHLIKVDQSGL-----SLQREIYFKHPEMVDTYVEYMAKVATLLGIKGNATKEMRKIVDFETKLANITTSAEDKAD--GIYRRIKLHHLIKLVPGFPWLKHMQAIFRGA--HVTDADVVLATPSTYLSKMNDIIKE-----TPKELLSNYVVWQMIRDKISLLSKPFRKARAVFNHKISGVKEQEPRWRTCTSITNDNLGVPLGTLYVRKYFNESTVGKIQLMIQEIKDTFKERVKEHEWIDDKTTQYVFQKADALRSKIGYANYVLRPIILKKRFKSLKIGKKTFFSNNVNVDKWVRHRLVGKLRKAVDKEKWPMFPQTINAMYQFYENEIGGGRGCLRRVFLALALALSLSYGAVGSIIGHEMTHGFDNTGRKFDKNGDIVQEWWSKSSLTNFKNRAQCIADQYSKFKIQNKYPLSGVVTLDENIADNGGTKLSYNAYHRWLKDNGNQEQVLPGLKYTNEQLFFIGYAQEYCSHARPKTEYIASLSDIHSPPKFRVIGTLSNMEEFSDAFKCPPGSPMNPKKKCEVW 676          

Query:  222 AFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNE---IHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGF---LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLIL--SEGTLQSSEDALEKEQITSYTK------FMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEE-KFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYP-TYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKG----MLREWWSKSSREEYSKKTQCIIDQYGQYKIYN-VSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDK-ENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            A S VC +  C  ++  IK  ++T+VDPCD+   + CG+  K   IP+  S+Y   S  E++ NNE   +H L   +P  N S +  K   F++SC+N++  +      +L+ + G     ++K +     NF  +    +M      +  F P+ +      P+     SE  +   +  L   QI  +T         N + D++ L   +K  +   V+  +K       I+      KY  ++ +S++     E  W+D +  +   + K++ ED  + V + DY+  L  +L+     +T   VL   + W ++ D+VPL S +    H   + ++LG          C   T+N+L  +V +++++ +F P  K  +E M+  I KA ++ I++V W+D  T      K +A+  K+GYPD L  E   + +Y ++ +T+   + +N V+  KF+  Q  Q +G  +PK  W      VNA+Y  + NE+V P+  L+ P  Y   +P S +YGAIG V+GHE+ HGFDT G KYD  G       E WSK++ + + +K +C++DQ+ ++K+ +   L   +T+GE+IAD  G +++++A++    +K    +LP L++ +++LFFLG A+  C    P A       DVH   K+R+ G  SN+ EFS+ +KC     MN  KKC VW
Sbjct:  129 ANSMVCQSKHCYNVAKSIKDALNTSVDPCDNFYEYACGSWVKNNDIPKFHSQYSRIS--ELSNNNEKILMHALNNTEP--NDSPNIKKIKTFFQSCMNVDAIDHMGEHPLLQHIKGLGSWAIDKDWNPKEWNF--YNTLAKMHREYPAEVFFTPDVH----SDPTKAHDKSEFLIMVDQATLNLPQIVYFTSPKIVKTVRNYMTDVICLAGYDKKDVKRKVHELLKFEAKIALISVPKILKKYV-RVPLSKLMKAVPEFPWMDHLKKLF--APKEITEDTKVIVLANDYLPKLFELLR-----NTDKDVLSDYMMWRLVKDVVPLLSNKFRKVHFDLKKKLLGAKHDKPRSTKCFGYTNNILGPLVGALFIREAFSPESKHKVETMMKGIIKAFEARIDQVPWIDKHTNEAVHEKADAVVVKVGYPDYLSDEKQFNQRYENLNITDSVHWFQNVVETDKFASWQTYQKLGSVVPKHHWITVPHLVNAFYVITKNEVVIPSGILQPPFFYPDEIPRSISYGAIGHVLGHELTHGFDTTGRKYDKNGEEIDKRSEAWSKNATKMFHEKAKCLVDQFSKFKVLDKFHLSGTKTLGENIADGGGLKLSFMAFRDLEKEKGPEEILPLLDMPSEKLFFLGYAQKECVHTTPAAEFLAATEDVHPPSKFRVIGTLSNLKEFSEVYKCKPGSYMNPVKKCEVW 806          

Query:  273 IKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLL----EIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGF----LLNKKYEDNLLNFLQ-FGLATRMVSFEAVQDPFNPEFNM-----LQIGKPSLIL--SEGTLQSSEDAL-----EKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGF----PSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTR---MAYIAWKSYSNDKENLVLPNL-NLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +KSM +TT+DPCDD   + CG  +    IP   S + S  +I  N N E+   L    +I+     +    KA  +Y +C++  L  K  +  + + +  F    + NK + +   +F++ F +  R +S         P FNM     L+    ++I+    GT+ S E  L       +  T+Y + M  +++ LG     +  +  +  L ++LAK      PS+    +  +  N+ +  ++    S ++  D +  +   +   +K+D  + V++++Y+  +  I       +T  +++   + W V        S++  D + +++  I G  G+   W+ C S  S      +  ++V  +F    K   E MI +I+      ++ + WMD +T+  A  K EAI   IGYPD + +++ +  +Y  +++ + K+  N  + +KF   + +  +G+ + K KW M    VNAYY+ + N+IVFPA  L+ P Y+   PNS NYG IG V+GHEI HGFD +G K++  G L  WW+ +S E + KKT C++ QY  Y+ +   L  +QT+GE+IADN G +    AY  WK  +N +E   LP L  L+ DQLFFL  A+ WC+  +P A +  ++  VH+  K R+ G  SN  EF++A+KC     MN   KC VW
Sbjct:    1 MKSM-NTTIDPCDDFYQYACGGWETKNLIPDTRSSW-SQFRILSNRNEELLKKLINSKDIRDKYKDNPAVMKAFDYYDACMDEKLIEKLGQQPLQDLIKMFGSWNVTNKNWTEADWDFMKTFVMIQRDLSIA-------PWFNMFVGTDLKDSTKTVIVFDQSGTILSREAMLFNTTYHAKIRTAYRRIMTSLMEKLGAGNEAEARMEEVYQLELELAKVKQRIQPSLIHLLSKVRQNNQPRTLKLAPPPSFLNLTDFLGHIFNLTDYNVKQDTEVVVYAMEYMVNMSRIFA-----NTPKRIVANYMMWHVAYFFASSLSKEFRDLYYEYREAITGTRGEDPRWQDCTSGVSGTFGMAIGLLFVDQTFKKESKTSAERMIKDIRNVFIDNLQNLNWMDEKTRKVAKEKAEAIRENIGYPDFIKNKTALELEYSGVRVDKTKYFWNQYERRKFYNQKNIDELGKPVDKTKWSMNPPTVNAYYSSTDNKIVFPAGILQDPFYEGDHPNSLNYGGIGMVVGHEITHGFDDNGRKFNKDGNLLTWWTNNSIEAFKKKTDCLVKQYSSYEFHGKKLNGLQTLGENIADNGGIKQSFQAYQKWKKDNNVEEEKRLPGLEKLSHDQLFFLSFAQIWCSAYRPEAAIRAIENGVHSPGKLRVIGSLSNSNEFAEAWKCPVGSRMNPKDKCAVW 672          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNL---RNKETRPTILEALNGFLLNKKYE--------DNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKH---IIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATAL-IKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKEN---LVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C    C + +  I + +D TV+PC D   + CG   K   +P G S++ +  Q+       +  + +     ++     K   +Y SC N ++   R+      ++  +  + +   +         +  L+ +    +T +       D  N   N++QI +  + LS+    +  ++   + +  Y +FM K+  +L     +     ++  I     KLA+ +       + +K  +K+ + ++Q     I W+D +N +       +  D+ + V++  ++  +  ++       T  ++L   + W +I  L    S+   +A        +GV   +  WK+CV+ T  VL      +YVK       K+  + +I +IK+A  S +  VTWMD  TK  A   K+E++ + IGYPD ++  + ++  Y ++ +T E   +N+++ ++F   Q ++  G+ + + +W M   +VNAYY+  +N I FP+  L+ P +D   P + NYGA+G V+GHE+ HGFD+ G  +D  G L  WW   S E + +   C+++QY  + + +V +   QT+ E+IADN G R+A+ A + +  DKEN     LP L L+ DQLFFLG A+ WC+    N++   +  D H+  + R++   SN  +F++A+ C  D  MN  KKC VW
Sbjct:   35 ICETKGCISAAFSILNKMDETVNPCRDFYQYACGKWLKDSVVPAGNSKWSAFHQVAEQNLRTLKKIFDRDDFASNGDIFRKVRDYYSSCTNKSIIEERDAAPLKKLISDVGSWSVTGGHTWTAETWNFEQALSLMHKLKSTPLFYMFVAADDKNSSQNIIQIQQAGITLSDREYYTRNES--DKVVKKYKEFMVKIATLLNGATADSTTGILMDEIFQFEKKLAEIYEPKERLRHSDKIYHKMTVEDLQQLAPAIPWMDYMNNLF---STPVGHDEPVVVYTPTFLKSMSDLVIR-----TDRRILANYMVWHLIKPLTTELSKPYREAALDLMRVEMGVESGAPTWKSCVTKTDTVLGYATGHLYVKQHDGKDVKEKAKQVIQSIKEAFISNLPTVTWMDEGTKTKARGEKMESVLDLIGYPDWIMDVAQLNAYYVNLVITPEMSFENHLNARRFVHQQTMEKRGKAVDRKEWHMTPVDVNAYYSLPNNYIAFPSGILQRPFFDPEFPQAMNYGAVGMVMGHELTHGFDSKGRLFDKNGNLESWWKNQSVEAFEEHVSCMVEQYSNFTVADVKVDGKQTLDENIADNGGLRLAFQAHRQW--DKENEKQPRLPGLELSRDQLFFLGFAQLWCSSSTKNSMHHPLLTDSHSPDRIRVHAAVSNSEQFAEAYDCPLDTPMNPAKKCRVW 710          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLE--IQPLQNHSQHQTK-AALFYKSCLNLN----LRNKETRPTILEALNGFLLNKKYEDNLLNFLQFGL---------ATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYM---SNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYP-TYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGML--REWWSKSSREEYSKKTQCIIDQYGQYKI-YNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDK--ENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            VC    C +++  I   +D +V PC D   F+CG   +   IP+  S Y + +++   V   +  +LE  I  +   S+   +  +  Y+SC++L     L ++  R  I E +  + L K + +   +  +  L            + S     DP     ++++I +    LS      S        I +Y K++  V  +L   +  +     I++L  KLA    S+ D      + N++ I ++        W+D +N +   + +++K+ + I V +L Y+  +  ++     ++T  +VL   + W VI D V   S+   D   +++  +LG  G  + WKTCV  T+ ++ +++ + Y++  FD   K     MI  +++A K  +  + WMD  TK     K +++ +++GYP  L           KY+ + M       N +   K +  ++L+ + + + K++W M    +NA Y+ + NE++ PAA L+ P  Y  G P+S ++GAIGS++GHE+ HGFD  G K++  G L    WWS  S + + +K +CI +QY QYK+     L    T+GE+IADN G + +Y A+ ++   K  E   LP LNLT++QLF++G  +A+C+  +          D H+  K+R+ G  SN  EFSKAF C  +  MN   KC VW
Sbjct:    1 VCHTKDCYSVARHINDSIDFSVSPCTDFYQFVCGGWMQKNPIPRSSSTYSTFTKLNTKVEKSLRGILEEGISAIPGASKKLMRMPSDVYESCMDLGTIDKLGDQPIRDMIKE-IGSWSLEKGWVEKDWDLSETLLYIHKKYTSAGGPLFSVHVSDDPIKNTRHIIEIDQAGPSLSREVYTDSPKI-----IKAYKKYIIDVGTLLRGKEAMEKYAQEIIDLETKLAN--ISVPDADKTETWFNRMTIKDLMKEAPGYDWLDHLNKMF--APEKIKDSEQIIVPALPYLKKMIKLI-----ENTPKRVLSNYVVWNVIQDEVSFLSKPYRDVRLRYRERVLGSKGHKKRWKTCVMYTNELVGDVLGAAYIQHHFDQHSKNIARDMIKEVRQAFKDNVNSIPWMDKTTKIAVSEKADSMKDEVGYPAYLKGGKKFIKRFKKYKGVTMKNNALFANRIAILKMAHKRMLKKLRKPVDKEEWPMDPQTINAMYSFNENEMIIPAAILQPPFFYPKGSPSSLSFGAIGSILGHEMTHGFDNTGRKFNKNGELTTSNWWSDGSLKGFDEKAKCIENQYSQYKVDGKYPLNGKLTLGENIADNGGFKSSYRAYHNWLKKKGDETWSLPGLNLTSEQLFYVGFGQAYCSNSRSTEQYLATLSDRHSEEKFRVIGTLSNSYEFSKAFGCRPEAPMNPVTKCSVW 680          

Query:  234 VCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNL-NLRNKETRPTI--LEALNGFLLNKKYE-DNLLNFLQFG----LATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHI-IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKS--ELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +C+++ C T++ +I   +D +VDPC D   F CG   +   +P G SR+ + + I       + +LLE       S+ + K   +Y SCLN   +     +P I  +  + G+ +   ++ DN +  L+       A    S     DP N   N++Q+ +  L L       ++ A EK  + +Y  +M ++  +LG  ++   + +  I+     LA        + +  K  +K+ I+E+Q+    + W++ +   +  S  ++ + + + +++ +Y+  +  ++ +     T   +L   + W ++   V    ++  +A ++    + G T KS    W+TC+  T + L   + +++VKA+FD   K+  E MI  I+ A K  ++ ++WMD +T+  A  K ++I + IG+P+ +L    + + Y   +++++ F +N ++F  FS   +   + +   KD+W M    VNAYY P+ N IVFPA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD +G LR WW  SS E +  +T+C+++QY +Y +    +   QT+GE+IADN G + AY A++S+   + +   LP +NLT DQLFF+G A+ WC++  P +  E +  D H+  +YR+ G  +N P+FS+ F C     MN  K C VW
Sbjct:   91 LCLSEACITVASQIVEAMDRSVDPCQDFYQFACGGWMRKNPLPDGRSRWSTFNSIWGQNQALLKHLLENGTFNGSSEAERKTQSYYLSCLNTQRIEELGAQPLIDLITKIGGWNMTGPWDKDNFMEVLKVVSGPYRAQPFFSVGVSADPKNSNSNVVQVDQSGLFLPSRDYYLNKTANEK-VLAAYLDYMVELGMLLGGEKSSTLVQMQQILEFETALANITVPQDQRRDEEKIYHKVTIAELQALAPAVDWLEFLTSSL--SPLELNDTEPVVLYAREYLQQVSELINK-----TDRSLLNNYMMWTLVQKSVATLDQRFENAQDRLLESLYG-TKKSCTPRWQTCIGNTDDTLGFALGALFVKATFDKLSKEIAEEMINEIRSAFKQALDRLSWMDEQTRKAAKEKADSIYDMIGFPEFILDPKELDDVYDGYEVSDDSFFQNMLNFYNFSARVMADQLRKTPNKDQWSMTPPTVNAYYMPTKNGIVFPAGILQAPFYAHDHPKALNFGGIGVVMGHELTHAFDDQGREYDKEGNLRPWWQNSSVEAFRVRTECMMEQYNRYTVNGEHVNGKQTLGENIADNGGLKAAYHAYQSWIQRNGQEKRLPAVNLTNDQLFFVGFAQVWCSVRTPESAHEGLMTDPHSPPRYRVIGTLANSPDFSRHFGCPEGTPMNSGKPCEVW 763          

Query:  198 PIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN-LRNKETRP--TILEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILG-LWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKS--ELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            P+ + V       C+   C T++G +   +D +VDPC D   F CG   K   +P+G+SR+   S +  +    + +LLE   ++  S+ + KA  +Y++C+N + +     +P   ++  L G+ LN  ++ DN    L+    + R   F  V    D  N   N++Q+ + SL L       ++ A EK  +T+Y  F+ ++  +LG   +  + ++  IV     LA       ++ +     +K+K+ ++++    + WI  +  V K     + + +L+ V++ +Y+  +  ++++     T   +L   +   V+  +V +  ++  DA  +F  E++  T KS    WK CVS T + L   + +++VK +F    K     M+  IK A +  +++V+WMD+ETK  A  K +AI N +GYP+ +++ + +   +   ++  E + +N + +  FS       + +   +++W M    VNAYYNP+ NE+V PA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++ QC+++QYG Y I    L    T+GE+IADN G + AY A+ ++   + E  +LP L +T  QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  EFSK F C  +  MN   KC +W
Sbjct:   27 PMQVNVHRRHPGSCLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISHLGGWALNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTANEK-YLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLKTLAPAVEWIPYLIEVFKPV--PLNQSELVVVYAKEYLQKVSDLIEK-----TNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFL-EVMYGTKKSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIASEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 711          

Query:  138 RRFCY*ILFLKDMIWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN-LRNKETRP--TILEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILG-LWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKS--ELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            RR    +  L  +++V   +   +  ++     C+   C T++G +   +D +VDPC D   F CG   K   +P+G+SR+   S +  +    + +LLE   ++  S+ + KA  +Y++C+N + +     +P   ++  L G+ LN  ++ DN    L+    + R   F  V    D  N   N++Q+ + SL L       ++ A EK  +T+Y  F+ ++  +LG   +  + ++  IV     LA       ++ +     +K+K+ ++++    + WI  +  V K     + + +L+ V++ +Y+  +  ++++     T   +L   +   V+  +V +  ++  DA  +F  E++  T KS    WK CVS T + L   + +++VK +F    K   E M+  IK A +  +++V+WMD+ETK  A  K +AI N +GYP+ +++ + +   +   ++  E + +N + +  FS       + +   +++W M    VNAYYNP+ NE+V PA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++ QC+++QYG Y I    L    T+GE+IADN G + AY A+ ++   + E  +LP L +T  QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  EFSK F C  +  MN   KC +W
Sbjct:   50 RRLLLSVCVLSVVLFV-SLICAGVFYKNGHPGSCLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISHLGGWALNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTANEK-YLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLKTLAPAVEWIPYLIEVFKPV--PLNQSELVVVYAKEYLQKVSDLIEK-----TNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFL-EVMYGTKKSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIAEEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 753          

Query:  138 RRFCY*ILFLKDMIWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLN-LRNKETRP--TILEALNGFLLNKKYE-DNLLNFLQ-FGLATRMVSFEAV---QDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILG-LWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVT---------------GKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSY-SNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            RR    +  L  +++V   +   +  ++     C+   C T++G +   +D +VDPC D   F CG   K   +P+G+SR+   S +  +    + +LLE   ++  S+ + KA  +Y++C+N + +     +P   ++  L G+ LN  ++ DN    L+    + R   F  V    D  N   N++Q+ + SL L       ++ A EK  +T+Y  F+ ++  +LG   +  + ++  IV     LA       ++ +     +K+K+ ++++    + WI  +  V K     + + +L+ V++ +Y+  +  ++++     T   +L   +   V+  +V +  ++  DA  +F   + G                   +  WK CVS T + L   + +++VK +F    K   E M+  IK A +  +++V+WMD+ETK  A  K +AI N +GYP+ +++ + +   +   ++  E + +N + +  FS       + +   +++W M    VNAYYNP+ NE+V PA  L+ P Y    P + N+G IG V+GHE+ H FD  G +YD  G LR WW  SS E + ++ QC+++QYG Y I    L    T+GE+IADN G + AY A+ ++   + E  +LP L +T  QLFF+G A+ WC++  P +  E +  D H+  ++R+ G  SN  EFSK F C  +  MN   KC +W
Sbjct:   63 RRLLLSVCVLSVVLFV-SLICAGVFYKNGHPGSCLTGPCITVAGAVMGALDRSVDPCHDFYNFACGGWVKNNPLPEGKSRWGPFSNLWEHNMLVMKHLLENTTMKGLSKAEEKAQRYYQACMNESKIEELGAKPLQQLISHLGGWALNGPWDKDNFQEVLRKVSGSLRTSPFFTVFVSTDSKNSNSNVIQVDQSSLGLPSRDYYLNKTANEK-YLTAYLNFLVELGVLLGGTEEASQTMMTEIVEFETTLANITVPQEERRDEELIYHKMKVEDLKTLAPAVEWIPYLIEVFKPV--PLNQSELVVVYAKEYLQKVSDLIEK-----TNKSLLNNYMVMKVVRKMVSVLDQRFQDAEQRFLEVMYGTKKMLGGFPGAFVDVSFSCTPRWKLCVSDTDSALGFALGAMFVKDTFAEDSKDIAEEMVGEIKWAFEDSLKDVSWMDAETKKAAKEKADAIYNMVGYPEFIMNATKLDKVFNDFEVVSELYFQNVMQYYNFSARVTADQLRKAPNRNQWSMTPPTVNAYYNPTKNEMVLPAGILQAPFYSRSWPKALNFGGIGVVMGHELTHAFDDQGREYDKDGNLRPWWKNSSVEAFKRQAQCMVEQYGNYSINQEPLNGKHTLGENIADNGGLKAAYKAYVNWIQKNGEEPMLPALGMTNHQLFFVGFAQVWCSVRTPESSHEGVITDPHSPSRFRVIGTISNSREFSKHFGCRANAPMNPKHKCELW 780          

Query:  174 MIWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILE----------ALNGF---------------LLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALE---KEQITSYTKFMNKVLDIL----GLWQNEKHI---IGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCS------EISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYK---IYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDK-ENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            +++++    I +       ++C    C   +  +   +D++V+PCD+   + CG   K   IP+  SRY +   +   +   +  +LE + +   +   TKA   YKSC N +L  +     +L+          A++G+                LN+KY   LL           V+F    D  +   +++   + +   S G L     A      E   +Y +FM  +  ++    GL  NE  I   +  +++L   +A    +  D++NP    NK+++ ++ +  +         W      +M      + + + I  +S +Y   L  +L +Y   D     L+  + W    ++V   S    D    F+  + G T ++ +W+ C    +N +   V  +YV+ +F    K+ +E MI +I++   S +++++WMD+ETK  A  K  AI  +IGY D+++ + +++N+Y+ +    EK+ +N +   ++   + L+ +  ++ KD+W  G+  VNA+Y+ S N+IVFPA  L+ P +  G   S NYG IG VIGHEI HGFD +G  YD  G L++WW+  S   + +++ CI+DQY  +       + L    T+GE+IADN G R AY A++++  D  E   LP ++L+ DQLFFL  A+ WC   +P   +  +K DVH+  K+R+ G   N PEF+KAF C +   M     C VW
Sbjct:   55 LLFIVIVALIILFATQKTDEMCTTADCTQSASRLIENMDSSVNPCDNFYQYACGGWLKKNIIPETSSRYSTFDILRDELEVILKGVLE-KTVDGEAAALTKAKTLYKSCTNESLIEQRGGAPLLDMLPDMFEWPIAVDGWEEKYGATWRLEDVIARLNEKYGTQLL-----------VNFFVGTDDRDSNSHIIHFDQQT---SLGLLSRDYYACTGPYAEACRAYEQFMIDLAKLIRSDRGLKVNETLIREEVARVMDLERDIANATDTPEDRNNPVLLYNKMELGDLNTNFTLEVDSKVFDWSHFTAKIMDAVNINISDSEKIINYSPNYYRRLNLVLAKYNKRD-----LQNYMVWRFAMNMVVGLSRAYRDTRKAFRKALSGTTSEAAVWRQCALYVNNNMDNAVGRLYVQEAFSEKSKELMEEMIKDIREVFISNMDDLSWMDAETKKAAEEKARAIRERIGYSDTIMDDEHLNNEYKDLSYNAEKYFENILQNLEYVQKKRLRKLRVKVNKDEWVTGAAVVNAFYSASKNQIVFPAGILQPPFFSKGQAKSLNYGGIGMVIGHEITHGFDDNGRNYDKDGDLKDWWTPDSTRRFLEQSNCIVDQYSNFSWELANGLHLNGNNTLGENIADNGGIRQAYQAYRNHVKDHGEEPPLPGIDLSHDQLFFLNFAQVWCGTHRPEQAVNSIKVDVHSPGKFRVLGSLQNFPEFAKAFSCNKSSYMIPDNVCRVW 769          

Query:  174 MIWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            MIWVLKFLPIAILVQSAFSKVCV DVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPT+LEALNGF LNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNE+HIIG+IVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEE+FLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW
Sbjct:    1 MIWVLKFLPIAILVQSAFSKVCVKDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTMLEALNGFSLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNERHIIGDIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEERFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 690          

Query:  177 IWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            I+V+  + I  L +    KVC  ++CK L  E+  +++ + DPCDD S+++CGNMDKV+ I  G++ ++S +QI  +V   + +LLE Q   N SQ QTKAA++Y+SC+N   RNK + P ILE          +E NL+  L+ GL +R  S E  QD  NPE+N+L IGKP+LILSEGTL++ E +  KE I SY K+M KVL+ILG+ +N +++I  I+ L+I+LAK  PSIADQS+P KYTNKL I  +Q +   ISWI +IN V++ S K++KEDD +  FSL+Y D L  ILKEY  D  K ++L+ DLEWAVI+ LVPLGS+ L +A+ +F SE  G+ GK E WK CV +TS+ L EIV +++VK+ F PSQKKDIELMI  IK ALK VIE +TWMDS TK++AL KL+AI +KIGYPDSL+SE+Y++ KY  I+MT +  L NY++FQ+F+  + L+ VGE+I  D+W MGS EVNAYYNP+SNEIVFPAA LR+P YDIGLP +YNYG IG VIGHEILHGFDT GSK+DSKG+LREWW+KSSR+EY  KTQCII+QY  Y I N  LPS+QTVGEDIADNAG RM+Y A  S    +E L LP ++L+ +QLFF+G  + WC++V  + + E++KGDVH++WKYRINGP SNMPEFSK F C R+K MNR KKCLVW
Sbjct:    4 IFVIGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVFRILPGQNSFNSFTQIRSSVTTTLKDLLEKQSTANRSQPQTKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIEVAQDAANPEYNILNIGKPTLILSEGTLRNFESS--KEIIASYIKYMKKVLNILGISKNYENVIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRNMQQKFPSISWIRVINEVLENSDKKLKEDDKLVAFSLEYFDSLIKILKEYLGDSQKKQILQRDLEWAVISSLVPLGSDALIEANEEFMSEGFGIKGKQEEWKKCVQITSSTLQEIVGNMFVKSQFQPSQKKDIELMIDYIKAALKDVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPIEMTFKNLLGNYINFQEFAREEYLKAVGEKISPDEWAMGSQEVNAYYNPTSNEIVFPAAILRFPFYDIGLPITYNYGGIGMVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGIRMSYFAANSKLEVREKLTLPGVDLSPEQLFFVGVGRTWCSIVTKSFIDERLKGDVHSVWKYRINGPMSNMPEFSKLFNCDRNKKMNRLKKCLVW 690          

Query:  177 IWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            I+V+  + I  L +    KVC  ++CK L  E+  +++ + DPCDD S+++CGNMDKVYSI  G++ +DS +QI  +V   + +LLE Q   N SQ Q KAA++Y+SC+N   RNK + P ILE          +E NL+   + GL +R  S E  QD  NPE+N+L IGKP+ +L EGTL+ SE +  KE I SY K+M KVL+ILG+ +  +++I  I+ L+I+LAK  PSIADQS+P KYTNKL I ++Q +   ISWI +IN V + +G ++KEDD +  FSL+Y+D    ILK Y  D  K ++L+ DLEWAVI+ LV LGS  L +A+ +F SE LGV GK E WK CV +TS+ L EIV +++VK+ F PSQKKDIE MI  IK ALK+VIE +TWMDS TK++AL KL+AI +KIGYPDSL+SE+Y++ KY   +M+   FL NY+ F +FS  + L+TVG++I  D+W MGS EVNAYYNP SNEIVFPAA LR+P YDIGLP +YNYG IG VIGHEILHGFDT GSK+DSKG+LREWW+KSSR+EY  KTQCII+QY  Y I N  LPS+QTVGEDIADNAG RM+Y A  S    +E L LP + L+ +QLFF+G  ++WC +V  N + +++K DVH++WKYRINGP SNMPEFSK F C R+KNMNR KKCLVW
Sbjct:    4 IFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLFKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESS-SKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 691          

Query:  177 IWVLKFLPIAILVQSAFSKVCVNDVCKTLSGEIKSMVDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            I+V+  + I  L +    KVC  ++CK L  E+  +++ + DPCDD S+++CGNMDKVYSI  G++ +D  +QI  +V   + +LLE Q   N SQ Q KAA++Y+SC+N   RNK + P ILE          +E NL+  L+ GL +R  S +  QD  NPE+N+L IGKP+ +L EGTL+ SE +  KE ITSY K+M KVL+ILG+ +  +++I  I+ L+I+LAK  PSIADQSNP KYTNKL I ++Q +   ISWI +IN V + +G ++KEDD +  FSL+Y+D    ILK Y  D  K ++L+ DLEWAVI+ LV LGS+ L +A  +F SE LGV GK E WK CV +TS+ L EIV +++VK+ F PSQKKDIE MI  IK ALKSVIE +TWMDS TK++AL KL+ I +KIGYPDSL+SE+Y++ KY   +M+   FL NY+ F +FS  + L+TVG++I  DKW MG  +VNAYYN  SNEIVFPAA  R+P YDIGLP +YNYG IG VIGHEILHGFDT GSK+DSKG+LREWW+KSSR+EY  KTQCII+QY  Y I N  LPS+QTVGEDIADNAG RM+Y A  S    +E L LP + L+ +QLFF+G  ++WC +V  N +  ++K DVH++WKYRINGP SNMPEFSK F C R+KNMNR KKCLVW
Sbjct:    4 IFVVGLIAILSLCKLYEGKVCETEICKKLGEELNKIMNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDYFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLLKSGLGSRFFSIDVAQDAANPEYNILNIGKPTFVLLEGTLRDSESS-SKEIITSYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSNPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDYSIKILKVYLGDRKKREILQKDLEWAVISRLVLLGSDALIEAQEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKSVIENLTWMDSNTKSSALEKLKTIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDKWAMGPQKVNAYYNALSNEIVFPAAIFRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDNQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 691          

Query:  285 VDTTVDPCDDMSAFICGNMDKVYSIPQGESRYDSDSQIEINVNNEIHNLLEIQPLQNHSQHQTKAALFYKSCLNLNLRNKETRPTILEALNGFLLNKKYEDNLLNFLQFGLATRMVSFEAVQDPFNPEFNMLQIGKPSLILSEGTLQSSEDALEKEQITSYTKFMNKVLDILGLWQNEKHIIGNIVNLNIKLAKGFPSIADQSNPNKYTNKLKISEIQSRCSEISWIDLINGVMKGSGKQMKEDDLINVFSLDYIDVLCGILKEYKNDDTKMKVLKMDLEWAVINDLVPLGSEQLTDAHNQFQSEILGVTGKSELWKTCVSVTSNVLSEIVSSIYVKASFDPSQKKDIELMIANIKKALKSVIEEVTWMDSETKATALIKLEAITNKIGYPDSLLSESYMSNKYRSIKMTEEKFLKNYVDFQKFSFNQLLQTVGEQIPKDKWDMGSWEVNAYYNPSSNEIVFPAAQLRYPTYDIGLPNSYNYGAIGSVIGHEILHGFDTDGSKYDSKGMLREWWSKSSREEYSKKTQCIIDQYGQYKIYNVSLPSIQTVGEDIADNAGTRMAYIAWKSYSNDKENLVLPNLNLTTDQLFFLGQAKAWCTLVKPNALLEKMKGDVHTIWKYRINGPQSNMPEFSKAFKCGRDKNMNRHKKCLVW 2243
            ++ + DPCDD S+++CGNMDKVYSI  G++ +DS +QI  +V   + +LLE Q   N SQ Q KAA++Y+SC+N   RNK + P ILE          +E NL+   + GL +R  S E  QD  NPE+N+L IGKP+ +L EGTL+ SE +  KE I SY K+M KVL+ILG+ +  +++I  I+ L+I+LAK  PSIADQS+P KYTNKL I ++Q +   ISWI +IN V + +G ++KEDD +  FSL+Y+D    ILK Y  D  K ++L+ DLEWAVI+ LV LGS  L +A+ +F SE LGV GK E WK CV +TS+ L EIV +++VK+ F PSQKKDIE MI  IK ALK+VIE +TWMDS TK++AL KL+AI +KIGYPDSL+SE+Y++ KY   +M+   FL NY+ F +FS  + L+TVG++I  D+W MGS EVNAYYNP SNEIVFPAA LR+P YDIGLP +YNYG IG VIGHEILHGFDT GSK+DSKG+LREWW+KSSR+EY  KTQCII+QY  Y I N  LPS+QTVGEDIADNAG RM+Y A  S    +E L LP + L+ +QLFF+G  ++WC +V  N + +++K DVH++WKYRINGP SNMPEFSK F C R+KNMNR KKCLVW
Sbjct:    1 MNKSADPCDDFSSYMCGNMDKVYSILPGQNSFDSFTQISSSVTTTLKDLLEKQSTANRSQPQAKAAIYYQSCMNKESRNKISHPIILEVAKEISNGNDFELNLIKLFKSGLGSRFFSIEVAQDAANPEYNILNIGKPTFVLLEGTLRDSESS-SKEIIASYIKYMKKVLNILGISKTYENLIDEILKLHIRLAKALPSIADQSDPEKYTNKLSIRDMQKKFPSISWIRVINEVFENTGIKLKEDDKLVAFSLEYLDSSIKILKVYLGDRKKREILQKDLEWAVISSLVSLGSNALIEANEEFMSESLGVKGKQEEWKKCVQMTSSTLQEIVGNMFVKSQFQPSQKKDIESMIDYIKAALKNVIENLTWMDSNTKSSALEKLKAIRHKIGYPDSLISETYLTKKYAPTEMSGNNFLGNYLTFLEFSTEEYLKTVGKKISPDEWAMGSQEVNAYYNPLSNEIVFPAAILRFPFYDIGLPITYNYGGIGVVIGHEILHGFDTQGSKFDSKGLLREWWTKSSRDEYLSKTQCIINQYASYVINNKPLPSLQTVGEDIADNAGMRMSYFAANSKLEVREKLTLPRVALSPEQLFFVGMGRSWCAIVTKNYIDDQLKEDVHSVWKYRINGPMSNMPEFSKVFNCDRNKNMNRQKKCLVW 652