Selenocysteine lyase

Overview
NameSelenocysteine lyase
Smed IDSMED30035128
Length (bp)1418
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Selenocysteine lyase (SMED30035128) t-SNE clustered cells

Violin plots show distribution of expression levels for Selenocysteine lyase (SMED30035128) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Selenocysteine lyase (SMED30035128) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Selenocysteine lyase (SMED30035128) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30035128

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 3

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
head regionSMED30035128SMESG000035935.1 SmedASXL_013029SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016
whole organism asexual adult RNA-sequencing evidence
head regionSMED30035128SMESG000035935.1 dd_Smed_v6_10675_0_1dd_Smed_v6PMID:28171748
Stückemann et al., 2017
whole organism asexual adult RNA-sequencing evidence
epidermisSMED30035128SMESG000035935.1 dd_Smed_v4_10675_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Selenocysteine lyase vs. Ensembl Human
Match: SCLY (selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:18161])

HSP 1 Score: 365.925 bits (938), Expect = 2.315e-122
Identity = 200/434 (46.08%), Postives = 263/434 (60.60%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYD---------------RYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            + K+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++SVV  F+                + AK P  ITS++EHDSI   L  +  +    +  V +   +G   ++ +++++   T LVT+MLANNETGI+ P+  IS+ ++    +        IL+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALY+R L             P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP    RLPNTC      NF+I GP      +LA+CR L ASVGAACHS   ++      S +L   G   D+ R+A+RLSVGR T++ +VD  V+DL  AV Q
Sbjct:   29 ERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAK-PHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGL---------GEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFP-GTQRLPNTC------NFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQP-----SPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQ 440          
BLAST of Selenocysteine lyase vs. Ensembl Human
Match: SCLY (selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:18161])

HSP 1 Score: 365.925 bits (938), Expect = 2.741e-122
Identity = 200/434 (46.08%), Postives = 263/434 (60.60%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYD---------------RYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            + K+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++SVV  F+                + AK P  ITS++EHDSI   L  +  +    +  V +   +G   ++ +++++   T LVT+MLANNETGI+ P+  IS+ ++    +        IL+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALY+R L             P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP    RLPNTC      NF+I GP      +LA+CR L ASVGAACHS   ++      S +L   G   D+ R+A+RLSVGR T++ +VD  V+DL  AV Q
Sbjct:   37 ERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAK-PHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGL---------GEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFP-GTQRLPNTC------NFSIRGPRLQGHVVLAQCRVLMASVGAACHSDHGDQP-----SPVLLSYGVPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAVAQ 448          
BLAST of Selenocysteine lyase vs. Ensembl Human
Match: SCLY (selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:18161])

HSP 1 Score: 256.914 bits (655), Expect = 1.170e-81
Identity = 135/289 (46.71%), Postives = 178/289 (61.59%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYD---------------RYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGK 900
            + K+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++SVV  F+                + AK P  ITS++EHDSI   L  +  +    +  V +   +G   ++ +++++   T LVT+MLANNETGI+ P+  IS+ ++    +        IL+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALY+R L             P+  M +GGGQERNFR GTENTPMI GLGK
Sbjct:   29 ERKVYMDYNATTPLEPEVIQAMTKAMWEAWGNPSSPYSAGRKAKDIINAARESLAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHANQTSKGHTGGHHSPVKGAK-PHFITSSVEHDSIRLPLEHLVEEQVAAVTFVPVSKVSGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGL---------GEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGK 307          
BLAST of Selenocysteine lyase vs. Ensembl Human
Match: SCLY (selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:18161])

HSP 1 Score: 228.409 bits (581), Expect = 1.259e-71
Identity = 118/235 (50.21%), Postives = 151/235 (64.26%), Query Frame = 1
Query:  472 TGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHS 1155
            +G   ++ +++++   T LVT+MLANNETGI+ P+  IS+ ++    +        IL+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALY+R L             P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP    RLPNTC      NF+I GP      +LA+CR L ASVGAACHS
Sbjct:    2 SGQAEVDDILAAVRPTTRLVTIMLANNETGIVMPVPEISQRIKALNQERVAAGLPPILVHTDAAQALGKQRVDVEDLGVDFLTIVGHKFYGPRIGALYIRGL---------GEFTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTQNCEAYEAHMRDVRDYLEERLEAEFGQKRIHLNSQFP-GTQRLPNTC------NFSIRGPRLQGHVVLAQCRVLMASVGAACHS 220          
BLAST of Selenocysteine lyase vs. Ensembl Human
Match: NFS1 (NFS1 cysteine desulfurase [Source:HGNC Symbol;Acc:HGNC:15910])

HSP 1 Score: 208.379 bits (529), Expect = 2.560e-61
Identity = 134/406 (33.00%), Postives = 217/406 (53.45%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFS---MYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVE 1296
            +YMD  ATTPLDP+V+D +L  +   + NP S   A G  +++A+E +R  VA++I A+P EIIFTSG TESNN+ +  V   FY    K   +IT+  EH  +      +E +G  ++  + +  K+G I++++L +++  DT+LV+VM  NNE G+ QPI  I +             K+  H+DA QA+GKI + V+D+ +D ++I GHK Y P+ +GA+Y+R              + ++++  GGGQER  RSGT  TP++VGLG A E+    ++  +  + K+ + L  ++++      M G        +     P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD  VE
Sbjct:   59 LYMDVQATTPLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVA-RFYRSRKK--HLITTQTEHKCVLDSCRSLEAEG-FQVTYLPV-QKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGRICS--------SRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKIYGPKGVGAIYIRR----------RPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACEVAQQEMEYDHKRISKLSERLIQNIMKSLPDVVMNG--------DPKHHYPGCINLSFAY---VEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTVE 424          
BLAST of Selenocysteine lyase vs. Ensembl Celegans
Match: F13H8.9 (pep chromosome:WBcel235:II:6279676:6281102:-1 gene:WBGene00017442.1 transcript:F13H8.9.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:F13H8.9)

HSP 1 Score: 266.159 bits (679), Expect = 8.113e-85
Identity = 162/407 (39.80%), Postives = 233/407 (57.25%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVS---INIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDL 1302
            KIY+D NATTPLD +V   I   +   W NPSS+ +  + A  AI ++R+H+  M   +   ++FTSGGTESNN V+   + +   + +K+P IIT+ IEH SI + L + E DG I +  V I   TG +  + ++ +L  DT LVT+MLANN+TG++QP+  I +A++E        N   LHSD  QA GKI ++V  L  D +T+VGHKFY PR GAL       N K       IP   M  GG QE  +RSGTENTPMIVGLG+AA++ +   +NI+     +++ RDY E  LL++  +    I+      + RLPNT +VA + ++   G ++L KC+   AS GAACH  +         S ILK CG    +    +R+S GR T   +++  V++L
Sbjct:    7 KIYLDNNATTPLDDRVKSAITDALDL-WANPSSNNENALKAADAILEARSHLGKMFNVDGECVVFTSGGTESNNWVIEGTIRN-AKKVSKLPHIITTNIEHPSILEPLKRREEDGEISVTYVSINPLTGFVTSQSILDALTSDTCLVTIMLANNDTGVLQPVSEIFQAIREKLK----TNVPFLHSDVAQAAGKIPVNVRSLSADAVTVVGHKFYGPRSGALI-----FNPKS----KRIP--PMLLGGNQESGWRSGTENTPMIVGLGEAAKVYNEGFLNIESI---LRQNRDYFEELLLKR--LRNSHIIHFI--GSQRLPNTSSVAFL-DYPSHGCDLLEKCQTFNASTGAACHKNEC--------SPILKACGIPFAVASKTVRISFGRSTKIAEIETVVDEL 380          
BLAST of Selenocysteine lyase vs. Ensembl Celegans
Match: B0205.6 (pep chromosome:WBcel235:I:10736697:10739911:1 gene:WBGene00015021.1 transcript:B0205.6.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:B0205.6)

HSP 1 Score: 202.986 bits (515), Expect = 3.075e-60
Identity = 128/403 (31.76%), Postives = 209/403 (51.86%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNP-SSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVE 1296
            IY+D  AT P+DP+V+D +L  M  ++ NP S ++  G  A+  +E +R HVAN+IKA+P +IIFTSG TESNN+ +  V    + + +    IIT   EH  +      +E +G  K+  + +  K G +++E+L  S+  +T LV++M  NNE G++QPI+ I +  +           +  H+DA QA GK+ I V+++ +D ++I  HK Y P+  GALYVR              + I++   GGGQER  RSGT   P+ +GLG+AA++    + M   H++++   L   +  K        + R  ++    P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T+  +V   ++
Sbjct:   13 IYLDVQATAPMDPRVVDAMLPYMINDFGNPHSRTHSYGWKAEEGVEQAREHVANLIKADPRDIIFTSGATESNNLAIKGVAK--FRKQSGKNHIITLQTEHKCVLDSCRYLENEG-FKVTYLPV-DKGGMVDMEQLTQSITAETCLVSIMFVNNEIGVMQPIKQIGELCR--------SKGVYFHTDAAQATGKVPIDVNEMKIDLMSISAHKIYGPKGAGALYVRR----------RPRVRIEAQMSGGGQERGLRSGTVAAPLCIGLGEAAKIADKEMAMDKAHVERLSQMLINGISDKLPH-----IIRNGDARHAYPGCVNLSFAY---VEGESLLMALKSIALSSGSACTSASLEP------SYVLRAIGSEEDLAHSSIRFGLGRFTTDEEVKHTID 379          
BLAST of Selenocysteine lyase vs. Ensembl Fly
Match: Nfs1 (gene:FBgn0032393 transcript:FBtr0080290)

HSP 1 Score: 202.601 bits (514), Expect = 2.013e-59
Identity = 140/400 (35.00%), Postives = 213/400 (53.25%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFN-ITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVD 1284
            +Y+D  ATTP+DP+V+D +L  ++  + NP S   A G   +SA+E +R  VA +I A+P EIIFTSG TESNN+ +  V   FY    K   +IT+  EH  +      +E +G  K+  + + +  G I++++L  ++  +T+LV++M  NNE G+ QP+  I K  +          ++  H+DA QA+GK+ + V+ + +D ++I GHK Y P+ +GALYVR       ++    L PI+S   GGGQER  RSGT   P+ VGLG AAEL    +D    + KK  D+L   LL + S     ++      A     T N  L  +F  + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T+  +VD
Sbjct:   64 LYLDAQATTPMDPRVLDAMLPYLTNFYGNPHSRTHAYGWETESAVEKAREQVATLIGADPKEIIFTSGATESNNIAVKGVA-RFYG--TKKRHVITTQTEHKCVLDSCRALENEG-FKVTYLPVLA-NGLIDLQQLEETITSETSLVSIMTVNNEIGVRQPVDEIGKLCR--------SRRVFFHTDAAQAVGKVPLDVNAMNIDLMSISGHKIYGPKGVGALYVR----RRPRV---RLEPIQS---GGGQERGLRSGTVPAPLAVGLGAAAELSLREMD----YDKKWVDFLSNRLLDRISSALPHVIRNGDAKA-----TYNGCLNLSFAYVEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGTDEDLAHSSIRFGIGRFTTVEEVD 425          
BLAST of Selenocysteine lyase vs. Ensembl Zebrafish
Match: scly (selenocysteine lyase [Source:ZFIN;Acc:ZDB-GENE-080204-30])

HSP 1 Score: 345.895 bits (886), Expect = 9.136e-115
Identity = 191/430 (44.42%), Postives = 257/430 (59.77%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF---------------YDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQ-NKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSM 1332
            +IYMDYNATTP DP+VI  +   +   W NPSS+Y  G+ A+  I  SR+ +A M+  +  +IIFTSGGTE+NN+V ++ V+ F                +    +P +I S +EHDSI      +  +G+  +  V +   T  + +E +I+++   T LV++MLANNETGII PI+ I + + E   +      +ILLH+DA QA+GKI +   +LGVDYLTIVGHKFY PR GAL+V +              P+  MF+GGGQERNFR GTENT MI GLGKAAELVS+N+  Y  H  +IR YLE  LL  F        S FP S + LPNTCN++++    + G  +L+ CRRL ASVGAACHS   ++      S IL  CG   D+  +A+R+SVGR TS+ DVD  VEDL + V Q   M
Sbjct:   36 RIYMDYNATTPADPEVIRVVTDALMDAWGNPSSNYLPGLKARDIIYHSRDAIARMVGGKAADIIFTSGGTEANNLVFHTAVEHFKKSMISAEGSTSSKQTNGRGSLPHVIISNVEHDSIKLTAENLLKEGKADVTFVPVSKVTARVEVEDVIAAIRPTTCLVSIMLANNETGIIMPIKDICQRVNEVNKQRAASAPRILLHTDAAQAIGKIRVDAHELGVDYLTIVGHKFYGPRTGALFVND---------PGKSTPVYPMFFGGGQERNFRPGTENTAMIAGLGKAAELVSLNLAEYETHFLEIRCYLEQKLLAVFGKDKIHFNSHFPGS-NNLPNTCNLSILGR-GLQGRRVLSTCRRLLASVGAACHSDRGDQ-----PSHILLSCGIPFDVATNALRISVGRSTSREDVDLVVEDLRDTVEQLERM 449          
BLAST of Selenocysteine lyase vs. Ensembl Zebrafish
Match: nfs1 (NFS1 cysteine desulfurase [Source:ZFIN;Acc:ZDB-GENE-060405-1])

HSP 1 Score: 204.142 bits (518), Expect = 5.879e-60
Identity = 144/410 (35.12%), Postives = 213/410 (51.95%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNK-ILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESA------SRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVE 1296
            +YMD+ ATTP+DP+V+D +L      + NP S   A G  ++SA+E +R  VA +I A+P EI+FTSG TESNNM +  V   FY   AK   IIT+ IEH  +      +E +G   +  + + S  G I++++L  ++  DT+LV++M  NNE G+ QP++ I          H  ++K +  H+DA QA+GKI + V D  VD ++I  HK Y P+ +GAL+VR             L P++S   GGGQER  RSGT  TP+ VGLG A E+    ++          D+   SLL    +   KI+S  P+         R P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD   E
Sbjct:   53 LYMDFQATTPMDPRVLDAMLPYQVNYYGNPHSRTHAYGWESESAMEKARKQVAGLIGADPREIVFTSGATESNNMSIKGVA-RFYK--AKKMHIITTQIEHKCVLDSCRVLETEG-FDITYLPVKS-NGLIDLKQLEDTIRPDTSLVSIMAINNEIGVKQPVKEIG---------HLCRSKNVFFHTDAAQAVGKIPVDVTDWKVDLMSISAHKIYGPKGVGALFVRRRPRVR-------LEPLQS---GGGQERGLRSGTVPTPLAVGLGAACEIAQQELEY---------DHKRVSLLANRLVQ--KIMSEIPDVVMNGDPDQRYPGCINLSFAY---VEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGADEDLAHSSIRFGIGRFTTEEEVDYTAE 418          
BLAST of Selenocysteine lyase vs. Ensembl Zebrafish
Match: scly (selenocysteine lyase [Source:ZFIN;Acc:ZDB-GENE-080204-30])

HSP 1 Score: 74.3294 bits (181), Expect = 1.161e-15
Identity = 36/71 (50.70%), Postives = 48/71 (67.61%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTE 303
            +IYMDYNATTP DP+VI  +   +   W NPSS+Y  G+ A+  I  SR+ +A M+  +  +IIFTSGGTE
Sbjct:   36 RIYMDYNATTPADPEVIRVVTDALMDAWGNPSSNYLPGLKARDIIYHSRDAIARMVGGKAADIIFTSGGTE 106          
BLAST of Selenocysteine lyase vs. Ensembl Xenopus
Match: scly (selenocysteine lyase [Source:NCBI gene;Acc:496582])

HSP 1 Score: 382.874 bits (982), Expect = 3.526e-129
Identity = 211/419 (50.36%), Postives = 276/419 (65.87%), Query Frame = 1
Query:   88 SKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF--------YDRYA-KIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNA 1311
            SKIY+DYNATTP   +V+  +   +   W NPSSSY AG  AK  I+ +R HVA M+  +P +IIFTSGGTE+NNMVL S V++F         +R A  +P IITS +EHDS++  LL ++   R ++  V + + TG I +E +IS++  +T LV++MLANNETG+I P+  +S+ L   + +   Q   KILLH+DA QALGK+++ V +LGV+YLTIVGHKFY PRIGALYVR L  +       SL+P   M YGGGQERNFR GTENTPMI GLGKAAELV ++  +Y  HM++IRDYLE  L   F     ++ SRFP  A RLPNTCNV+L+    + G E L+ C+ LQAS+GAACHS   ++      S +L + G   +   SA+RLSVGRETS+ DVD  V DL  A
Sbjct:   24 SKIYLDYNATTPPATEVVKAVEEALREAWGNPSSSYTAGCKAKELIDTARAHVAKMVGGKPEDIIFTSGGTEANNMVLFSTVENFNSTSKERQNNRVALALPHIITSNVEHDSVALPLLHLQKTHRAEITFVPVSTVTGRIEVEDIISAVRPNTCLVSIMLANNETGVIMPVGELSQCLASMSKERSAQGLPKILLHTDAAQALGKVEVDVQELGVNYLTIVGHKFYGPRIGALYVRGLGQH------SSLLP---MLYGGGQERNFRPGTENTPMIAGLGKAAELVFLHCAVYEAHMRRIRDYLEERLEAVFEDR-IRLNSRFP-GAERLPNTCNVSLLKP-AMLGHEWLSHCQYLQASIGAACHSDRGDR-----PSPVLLNSGVPQEAATSAVRLSVGRETSQDDVDLIVRDLEQA 425          
BLAST of Selenocysteine lyase vs. Ensembl Xenopus
Match: scly (selenocysteine lyase [Source:NCBI gene;Acc:496582])

HSP 1 Score: 381.333 bits (978), Expect = 1.010e-128
Identity = 210/418 (50.24%), Postives = 275/418 (65.79%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF--------YDRYA-KIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNA 1311
            KIY+DYNATTP   +V+  +   +   W NPSSSY AG  AK  I+ +R HVA M+  +P +IIFTSGGTE+NNMVL S V++F         +R A  +P IITS +EHDS++  LL ++   R ++  V + + TG I +E +IS++  +T LV++MLANNETG+I P+  +S+ L   + +   Q   KILLH+DA QALGK+++ V +LGV+YLTIVGHKFY PRIGALYVR L  +       SL+P   M YGGGQERNFR GTENTPMI GLGKAAELV ++  +Y  HM++IRDYLE  L   F     ++ SRFP  A RLPNTCNV+L+    + G E L+ C+ LQAS+GAACHS   ++      S +L + G   +   SA+RLSVGRETS+ DVD  V DL  A
Sbjct:   16 KIYLDYNATTPPATEVVKAVEEALREAWGNPSSSYTAGCKAKELIDTARAHVAKMVGGKPEDIIFTSGGTEANNMVLFSTVENFNSTSKERQNNRVALALPHIITSNVEHDSVALPLLHLQKTHRAEITFVPVSTVTGRIEVEDIISAVRPNTCLVSIMLANNETGVIMPVGELSQCLASMSKERSAQGLPKILLHTDAAQALGKVEVDVQELGVNYLTIVGHKFYGPRIGALYVRGLGQH------SSLLP---MLYGGGQERNFRPGTENTPMIAGLGKAAELVFLHCAVYEAHMRRIRDYLEERLEAVFEDR-IRLNSRFP-GAERLPNTCNVSLLKPA-MLGHEWLSHCQYLQASIGAACHSDRGDR-----PSPVLLNSGVPQEAATSAVRLSVGRETSQDDVDLIVRDLEQA 416          
BLAST of Selenocysteine lyase vs. Ensembl Xenopus
Match: scly (selenocysteine lyase [Source:NCBI gene;Acc:496582])

HSP 1 Score: 357.836 bits (917), Expect = 1.609e-119
Identity = 200/419 (47.73%), Postives = 270/419 (64.44%), Query Frame = 1
Query:   88 SKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF--------YDRYA-KIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNA 1311
            SKIY+DYNATTP   +V+  +   +   W NPSSSY AG  AK  I+ +R HVA M+  +P +IIFTSGGTE+NNMVL S V++F         +R A  +P IITS +EHDS++  LL ++   R ++  V + + TG I +E +IS++  +T LV++MLANNETG+I P+  +S+ L   + +   Q   KILLH+DA QALGK+++ V +LGV+YLTIVGHKFY PRIGALYVR L  +       SL+P   M YGGGQERNFR GTENTPMI GLGKAAELV ++  +Y  HM++IRDYLE  L  + S +   ++ +F +  +    +C  A++ N    G   L+ C+ LQAS+GAACHS   ++      S +L + G   +   SA+RLSVGRETS+ DVD  V DL  A
Sbjct:   15 SKIYLDYNATTPPATEVVKAVEEALREAWGNPSSSYTAGCKAKELIDTARAHVAKMVGGKPEDIIFTSGGTEANNMVLFSTVENFNSTSKERQNNRVALALPHIITSNVEHDSVALPLLHLQKTHRAEITFVPVSTVTGRIEVEDIISAVRPNTCLVSIMLANNETGVIMPVGELSQCLASMSKERSAQGLPKILLHTDAAQALGKVEVDVQELGVNYLTIVGHKFYGPRIGALYVRGLGQH------SSLLP---MLYGGGQERNFRPGTENTPMIAGLGKAAELVFLHCAVYEAHMRRIRDYLEERLEVRKSRF--ILMKKFSDCWNI---SCAHAMLAN----GYSWLSHCQYLQASIGAACHSDRGDR-----PSPVLLNSGVPQEAATSAVRLSVGRETSQDDVDLIVRDLEQA 410          
BLAST of Selenocysteine lyase vs. Ensembl Xenopus
Match: scly (selenocysteine lyase [Source:NCBI gene;Acc:496582])

HSP 1 Score: 341.273 bits (874), Expect = 3.233e-113
Identity = 196/421 (46.56%), Postives = 262/421 (62.23%), Query Frame = 1
Query:   82 NDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF--------YDRYA-KIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNA 1311
            ND KIY+DYNATTP   +V+  +   +   W NPSSSY AG  AK  I+ +R HVA M+  +P +IIFTSGGTE+NNMVL S V++F         +R A  +P IITS +EHDS++  LL ++   R ++  V + + TG I +E +IS++  +T LV++MLANNETG+I P+  +S+ L   + +   Q   KILLH+DA QALGK+++ V +LGV+YLTIVGHKFY PRIGALYVR L  +       SL+P   M YGGGQERNF                 +LV ++  +Y  HM++IRDYLE  L   F     ++ SRFP  A RLPNTCNV+L+    + G E L+ C+ LQAS+GAACHS   ++      S +L + G   +   SA+RLSVGRETS+ DVD  V DL  A
Sbjct:   13 NDCKIYLDYNATTPPATEVVKAVEEALREAWGNPSSSYTAGCKAKELIDTARAHVAKMVGGKPEDIIFTSGGTEANNMVLFSTVENFNSTSKERQNNRVALALPHIITSNVEHDSVALPLLHLQKTHRAEITFVPVSTVTGRIEVEDIISAVRPNTCLVSIMLANNETGVIMPVGELSQCLASMSKERSAQGLPKILLHTDAAQALGKVEVDVQELGVNYLTIVGHKFYGPRIGALYVRGLGQH------SSLLP---MLYGGGQERNF-----------------QLVFLHCAVYEAHMRRIRDYLEERLEAVFEDR-IRLNSRFP-GAERLPNTCNVSLLKP-AMLGHEWLSHCQYLQASIGAACHSDRGDR-----PSPVLLNSGVPQEAATSAVRLSVGRETSQDDVDLIVRDLEQA 399          
BLAST of Selenocysteine lyase vs. Ensembl Xenopus
Match: ncdn (neurochondrin [Source:Xenbase;Acc:XB-GENE-968620])

HSP 1 Score: 202.601 bits (514), Expect = 2.960e-59
Identity = 137/413 (33.17%), Postives = 218/413 (52.78%), Query Frame = 1
Query:   82 NDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPE------SASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVE 1296
            N   +YMD  ATT LDP+V+DR+L  M   + NP S   A G   + A+E +R  VA++I A+  EIIFTSG TESNN+ L  V   FY    +   I+T+  EH  +      +E +G  ++  + +  K G ++++ L  S+  DT+LV++M  NNE G+ QPI+ I +             KI  H+DA QA+GKI ++V+ + +D ++I GHK Y P+ +GA+YVR              + ++++  GGGQER  RSGT   P++VGLG A ++    ++  Y H ++I     ++L ++ +     I+S+ PE      +  R P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD  V+
Sbjct:   42 NLRPLYMDVQATTSLDPRVLDRMLPYMVNYYGNPHSRTHAYGWETEKAVEKAREQVASLIGADSREIIFTSGATESNNLALKGVA-KFYKSRKR--HILTTQTEHKCVLDSCRSLEAEG-FQVTYLPV-QKNGLVDLKVLEDSIRPDTSLVSIMAVNNEIGVKQPIQEIGQICS--------SRKIFFHTDAAQAVGKIPLNVNQMKIDLMSISGHKIYGPKGVGAIYVRR----------RPRVRMEALISGGGQERGLRSGTVPAPLVVGLGAACKVSQEELE--YDH-RRI-----SALAKRLTQ---NIMSQIPEVVLNGDAEHRYPGCINLSFAY---VEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGADEDLAHSSIRFGIGRFTTEEEVDYTVK 411          
BLAST of Selenocysteine lyase vs. Ensembl Mouse
Match: Scly (selenocysteine lyase [Source:MGI Symbol;Acc:MGI:1355310])

HSP 1 Score: 365.925 bits (938), Expect = 8.792e-123
Identity = 198/433 (45.73%), Postives = 265/433 (61.20%), Query Frame = 1
Query:   70 INKMNDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRY--------------AKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            +  + D K+YMDYNATTPL+P+VI  +   M   W NPSSSY +G  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++S+V  F+++                  P  IT T+EHDSI   L  +  +   ++  V +    G   +E +++++   T LVT+MLANNETG+I P+  IS+ ++            ++L+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALYVR +           L P+  M +GGGQE NFR GTENTPMI GLGKAA+LVS N + Y  HM+ IRDYLE  L  +F      + SRFP    RLPNTCN + +    + G  +LA+CR L ASVGA+CHS   ++      S +L  CG  +D+ R+A+RLSVGR T++ DVD  V+DL  AV Q
Sbjct:   12 VESLPDRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGV---------GKLTPLYPMLFGGGQEWNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKR-IHLNSRFP-GVERLPNTCNFS-IQGSQLQGYTVLAQCRTLLASVGASCHSNHEDR-----PSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDLIVQDLKQAVAQ 427          
BLAST of Selenocysteine lyase vs. Ensembl Mouse
Match: Nfs1 (nitrogen fixation gene 1 (S. cerevisiae) [Source:MGI Symbol;Acc:MGI:1316706])

HSP 1 Score: 209.92 bits (533), Expect = 4.142e-62
Identity = 135/407 (33.17%), Postives = 216/407 (53.07%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDG-RIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFS---MYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVE 1296
            +YMD  ATTPLDP+V+D +L  +   + NP S   A G  +++A+E +R  VA++I A+P EIIFTSG TESNN+ +  V   FY    K   ++T+  EH  +      +E +G R+    V+   K+G I++++L +++  DT+LV+VM  NNE G+ QPI  I +             K+  H+DA QA+GKI + V+D+ +D ++I GHK Y P+ +GA+Y+R              + ++++  GGGQER  RSGT  TP++VGLG A EL    ++  +  + K+ + L  ++++      M G        +     P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD   E
Sbjct:   61 LYMDVQATTPLDPRVLDAMLPYLVNYYGNPHSRTHAYGWESEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVA-RFYRSRKK--HLVTTQTEHKCVLDSCRSLEAEGFRVTYLPVQ---KSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAEIGQICS--------SRKVYFHTDAAQAVGKIPLDVNDMKIDLMSISGHKLYGPKGVGAIYIRR----------RPRVRVEALQSGGGQERGMRSGTVPTPLVVGLGAACELAQQEMEYDHKRISKLAERLVQNIMKNLPDVVMNG--------DPKQHYPGCINLSFAY---VEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAE 426          
BLAST of Selenocysteine lyase vs. Ensembl Mouse
Match: Scly (selenocysteine lyase [Source:MGI Symbol;Acc:MGI:1355310])

HSP 1 Score: 186.422 bits (472), Expect = 1.703e-55
Identity = 98/233 (42.06%), Postives = 141/233 (60.52%), Query Frame = 1
Query:   79 MNDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRY--------------AKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHK 729
            ++  K+YMDYNATTPL+P+VI  +   M   W NPSSSY +G  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++S+V  F+++                  P  IT T+EHDSI   L  +  +   ++  V +    G   +E +++++   T LVT+MLANNETG+I P+  IS+ ++            ++L+H+DA QALGK  + V+DLGVD+LTIVGHK
Sbjct:   17 LSSRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHK 249          
BLAST of Selenocysteine lyase vs. Ensembl Mouse
Match: Scly (selenocysteine lyase [Source:MGI Symbol;Acc:MGI:1355310])

HSP 1 Score: 147.132 bits (370), Expect = 1.024e-40
Identity = 80/205 (39.02%), Postives = 118/205 (57.56%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRY--------------AKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAG 657
            K+YMDYNATTPL+P+VI  +   M   W NPSSSY +G  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++S+V  F+++                  P  IT T+EHDSI   L  +  +   ++  V +    G   +E +++++   T LVT+MLANNETG+I P+  IS+ ++            ++L+H+DA 
Sbjct:   41 KVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQIRAASGLPRVLVHTDAA 245          
BLAST of Selenocysteine lyase vs. Ensembl Mouse
Match: Scly (selenocysteine lyase [Source:MGI Symbol;Acc:MGI:1355310])

HSP 1 Score: 143.28 bits (360), Expect = 1.158e-39
Identity = 78/199 (39.20%), Postives = 118/199 (59.30%), Query Frame = 1
Query:   70 INKMNDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRY--------------AKIPMIITSTIEHDSISKVLLKMEVDGRI--------KLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQ 600
            +  + D K+YMDYNATTPL+P+VI  +   M   W NPSSSY +G  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++S+V  F+++                  P  IT T+EHDSI ++ L+  V+ ++        ++  V +    G   +E +++++   T LVT+MLANNETG+I P+  IS+ ++
Sbjct:   10 VESLPDRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSI-RLPLEHLVENQMAVYMFCISEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIK 207          
BLAST of Selenocysteine lyase vs. UniProt/SwissProt
Match: sp|Q5U4Q9|SCLY_XENTR (Selenocysteine lyase OS=Xenopus tropicalis OX=8364 GN=scly PE=2 SV=2)

HSP 1 Score: 381.333 bits (978), Expect = 5.349e-128
Identity = 210/418 (50.24%), Postives = 275/418 (65.79%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF--------YDRYA-KIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNA 1311
            KIY+DYNATTP   +V+  +   +   W NPSSSY AG  AK  I+ +R HVA M+  +P +IIFTSGGTE+NNMVL S V++F         +R A  +P IITS +EHDS++  LL ++   R ++  V + + TG I +E +IS++  +T LV++MLANNETG+I P+  +S+ L   + +   Q   KILLH+DA QALGK+++ V +LGV+YLTIVGHKFY PRIGALYVR L  +       SL+P   M YGGGQERNFR GTENTPMI GLGKAAELV ++  +Y  HM++IRDYLE  L   F     ++ SRFP  A RLPNTCNV+L+    + G E L+ C+ LQAS+GAACHS   ++      S +L + G   +   SA+RLSVGRETS+ DVD  V DL  A
Sbjct:   16 KIYLDYNATTPPATEVVKAVEEALREAWGNPSSSYTAGCKAKELIDTARAHVAKMVGGKPEDIIFTSGGTEANNMVLFSTVENFNSTSKERQNNRVALALPHIITSNVEHDSVALPLLHLQKTHRAEITFVPVSTVTGRIEVEDIISAVRPNTCLVSIMLANNETGVIMPVGELSQCLASMSKERSAQGLPKILLHTDAAQALGKVEVDVQELGVNYLTIVGHKFYGPRIGALYVRGLGQH------SSLLP---MLYGGGQERNFRPGTENTPMIAGLGKAAELVFLHCAVYEAHMRRIRDYLEERLEAVFEDR-IRLNSRFP-GAERLPNTCNVSLLKPA-MLGHEWLSHCQYLQASIGAACHSDRGDR-----PSPVLLNSGVPQEAATSAVRLSVGRETSQDDVDLIVRDLEQA 416          
BLAST of Selenocysteine lyase vs. UniProt/SwissProt
Match: sp|Q66IQ6|SCLY_XENLA (Selenocysteine lyase OS=Xenopus laevis OX=8355 GN=scly PE=2 SV=1)

HSP 1 Score: 376.326 bits (965), Expect = 5.163e-126
Identity = 208/428 (48.60%), Postives = 277/428 (64.72%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAK----------IPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKIL--SRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSM 1332
            KIY+DYNATTP   +V+  +   +   W NPSSSY AG  AK  I+ +R  +A M+  +P +IIFTSGGTE+NNMVL S V++F +R +K          +P IITS +EHDS++  LL+++   + ++  V + + TG + +E +IS++  +T LV++MLANNETG+I P+  +S+ L   + K   Q   +ILLH+DA QALGK+++ V +LGV+YLTIVGHKFY PRIGALYV  L             P+  M YGGG+E NFR GTENTPMI GLG+AAELVS++   Y  HM++IRDYLE  L    +++G +I   SRFP  A RLPNTCNV+L+    + G E L+ C+ LQASVGAACHS   +     + S +L   G   D  RSA+RLSVGRETS+ DVD  V DL  A  Q L M
Sbjct:   16 KIYLDYNATTPPAREVVGTVAEALQEAWGNPSSSYTAGCKAKELIDTARARIAKMVGGKPEDIIFTSGGTEANNMVLFSAVENF-NRTSKERQNNNVDWALPHIITSNVEHDSVALPLLQLQKTHKAEITFVPVSTVTGRVEVEDVISAVRPNTCLVSIMLANNETGVIMPVGELSQCLASLSRKRSAQGLPEILLHTDAAQALGKVEVDVQELGVNYLTIVGHKFYGPRIGALYVGGLGHQS---------PLLPMLYGGGREGNFRPGTENTPMIAGLGQAAELVSLHCAAYEVHMRRIRDYLEQKL---EAVFGDRIRLNSRFP-GAERLPNTCNVSLLKPA-VLGREWLSHCQYLQASVGAACHSDRGD-----SPSPVLLKSGVPQDAARSAVRLSVGRETSQDDVDLIVRDLEQAA-QLLGM 422          
BLAST of Selenocysteine lyase vs. UniProt/SwissProt
Match: sp|A2VDS1|SCLY_BOVIN (Selenocysteine lyase OS=Bos taurus OX=9913 GN=SCLY PE=2 SV=1)

HSP 1 Score: 373.629 bits (958), Expect = 8.042e-125
Identity = 202/429 (47.09%), Postives = 266/429 (62.00%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYA--------------KIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            K+YMDYNATTPL+P+VI+ +   M   W NPSSSY AG  AK  I  +R ++A MI  +P ++IFTSGGTESNN+V+ SVV  F+  +A               +P IIT T+EHDSI   L  +  +   ++  V +    G +  E +++++   T LVT+MLANNETG+I P+  IS+ ++    +        +L+H+DA QALGK  + V DLGVD+LTIVGHKFY PRIGALYVR L             P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP  A RLPNTC      NF+I GP+     +LA+CR L ASVGAACHS   ++      S +L  CG  +D+ R+AIRLSVGR +++ +VD  V+DL  AV
Sbjct:   24 KVYMDYNATTPLEPEVIEAMTEAMREAWGNPSSSYPAGRKAKEIINTARENLAKMIGGQPQDVIFTSGGTESNNLVIQSVVKHFHKVHAANGDTGGHPNPVDGALPHIITCTVEHDSIRLPLEHLREERVAEVTFVPVSKVNGQVEAEDILAAVRPATCLVTIMLANNETGVIMPVPEISRRVRALNQQRVAGGLPGVLVHTDAAQALGKQRVDVRDLGVDFLTIVGHKFYGPRIGALYVRGL---------GEHTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVAENGEAYEAHMRGVRDYLEERLAAEFGER-IHLNSQFP-GAERLPNTC------NFSIRGPQLQGRAVLAQCRTLLASVGAACHSDLGDRP-----SPVLLSCGVPVDVARNAIRLSVGRSSTRAEVDLVVQDLKQAV 430          
BLAST of Selenocysteine lyase vs. UniProt/SwissProt
Match: sp|Q9JLI6|SCLY_MOUSE (Selenocysteine lyase OS=Mus musculus OX=10090 GN=Scly PE=1 SV=1)

HSP 1 Score: 369.007 bits (946), Expect = 4.041e-123
Identity = 199/433 (45.96%), Postives = 266/433 (61.43%), Query Frame = 1
Query:   70 INKMNDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRY--------------AKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            +  + D K+YMDYNATTPL+P+VI  +   M   W NPSSSY +G  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++S+V  F+++                  P  IT T+EHDSI   L  +  +   ++  V +    G   +E +++++   T LVT+MLANNETG+I P+  IS+ ++            ++L+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALYVR +           L P+  M +GGGQERNFR GTENTPMI GLGKAA+LVS N + Y  HM+ IRDYLE  L  +F      + SRFP    RLPNTCN + +    + G  +LA+CR L ASVGA+CHS   ++      S +L  CG  +D+ R+A+RLSVGR T++ DVD  V+DL  AV Q
Sbjct:   12 VESLPDRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVSGRKAKDIINAARASLAKMIGGKPQDIIFTSGGTESNNLVIHSMVRCFHEQQTLKGNMVDQHSPEEGTRPHFITCTVEHDSIRLPLEHLVENQMAEVTFVPVSKVNGQAEVEDILAAVRPTTCLVTIMLANNETGVIMPVSEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGV---------GKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKR-IHLNSRFP-GVERLPNTCNFS-IQGSQLQGYTVLAQCRTLLASVGASCHSNHEDR-----PSPVLLSCGIPVDVARNAVRLSVGRGTTRADVDLIVQDLKQAVAQ 427          
BLAST of Selenocysteine lyase vs. UniProt/SwissProt
Match: sp|Q68FT9|SCLY_RAT (Selenocysteine lyase OS=Rattus norvegicus OX=10116 GN=Scly PE=1 SV=1)

HSP 1 Score: 366.696 bits (940), Expect = 3.694e-122
Identity = 199/428 (46.50%), Postives = 264/428 (61.68%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRY--------------AKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            + K+YMDYNATTPL+P+VI  +   M   W NPSSSY AG  AK  I  +R  +A MI  +P +IIFTSGGTESNN+V++S V  F+++                  P  IT T+EHDSI   L  +  D   ++  V +    G + +E +++++   T LVT+MLANNETG+I PI  IS+ ++            ++L+H+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALYVR +           L P+  M +GGGQERNFR GTENTPMI GLGKAA+LVS N + Y  HM+ IRDYLE  L  +F      + SRFP    RLPNTCN + +    + G  +LA+C+ L ASVGA+CHS   ++      S +L  CG  +D+ R+A+RLSVGR T++ +VD  V+DL  AV Q
Sbjct:   17 NRKVYMDYNATTPLEPEVIQAVTEAMKEAWGNPSSSYVAGRKAKDIINTARASLAKMIGGKPQDIIFTSGGTESNNLVIHSTVRCFHEQQTLQGRTVDQISPEEGTRPHFITCTVEHDSIRLPLEHLVEDQVAEVTFVPVSKVNGQVEVEDILAAVRPTTCLVTIMLANNETGVIMPISEISRRIKALNQIRAASGLPRVLVHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGV---------GKLTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAADLVSENCETYEAHMRDIRDYLEERLEAEFGKR-IHLNSRFP-GVERLPNTCNFS-IQGSQLRGYMVLAQCQTLLASVGASCHSDHEDR-----PSPVLLSCGIPVDVARNAVRLSVGRSTTRAEVDLIVQDLKQAVNQ 427          
BLAST of Selenocysteine lyase vs. TrEMBL
Match: A0A2U3WN64 (selenocysteine lyase OS=Odobenus rosmarus divergens OX=9708 GN=SCLY PE=4 SV=1)

HSP 1 Score: 385.956 bits (990), Expect = 4.973e-127
Identity = 212/434 (48.85%), Postives = 274/434 (63.13%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYD-RYAK-------------IPMIITSTIEHDSISKVLLKMEVDGRI-KLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            D K+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I+ +R +VA MI  +P +IIFTSGGTESNN+V++SVV  F+  R +K              P +IT T+EHDSI ++ L+  V+ R+  +  V +    G + +E +++++   T LVT+MLANNETG+I PI  IS+ ++    K        ILLH+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALYVR L           L P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP    RLPNTC      NF+I GP+     +LA+CR L ASVGAACHS  A++      S +L  CG   D+ R+A+RLSVGR T++ +VD  V+DL  AV Q
Sbjct:   29 DRKVYMDYNATTPLEPEVIQAMTEAMREAWGNPSSPYPAGRKAKDIIDTARENVAKMICGKPQDIIFTSGGTESNNLVIHSVVKHFHQTRPSKGSPAELCSPLDGATPHLITCTVEHDSI-RLPLEHLVEERVAAVTFVPVSKVNGQVEVEDILAAVCPATCLVTIMLANNETGVIMPISEISQRIKALNQKRAASRLPVILLHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGL---------GELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTRNCEAYEAHMRDVRDYLEERLEAEFDKQRIHLNSQFP-GTERLPNTC------NFSIQGPQLQGHAVLARCRALLASVGAACHSDRADR-----PSPVLLSCGIPFDVARNALRLSVGRSTTRAEVDLIVQDLKQAVAQ 440          
BLAST of Selenocysteine lyase vs. TrEMBL
Match: A0A2Y9G6J3 (selenocysteine lyase OS=Neomonachus schauinslandi OX=29088 GN=SCLY PE=4 SV=1)

HSP 1 Score: 385.185 bits (988), Expect = 9.854e-127
Identity = 212/434 (48.85%), Postives = 273/434 (62.90%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYD-RYAK-------------IPMIITSTIEHDSISKVLLKMEVDGRI-KLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            DSK+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I+ +R +VA MI  +P +IIFTSGGTESNN+V++SVV  F+  R +K              P +IT T+EHDSI ++ L+  V+ R+  +  V +    G + +E +++++   T LVT+MLANNETG+I PI  IS+ ++    K        +LLH+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALYVR L           L P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP    RLPNTC      NF+I GP+     +LA+CR L ASVGAACHS      H    S +L  CG   D+ R+A+RLSVGR T++ +VD  V+DL  AV Q
Sbjct:   29 DSKVYMDYNATTPLEPEVIQAMTEAMREAWGNPSSPYPAGRKAKDIIDTARENVAKMICGKPQDIIFTSGGTESNNLVIHSVVKHFHQTRPSKGSLAELCSPLDRATPHLITCTVEHDSI-RLPLEHLVEERVAAVTFVPVSKVNGQVEVEDILAAVCPATCLVTIMLANNETGVIMPISEISQQIKALNQKRVASGLPVVLLHTDAAQALGKRHVDVEDLGVDFLTIVGHKFYGPRIGALYVRGL---------GELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTRNCEAYEAHMRDVRDYLEERLEAEFGKQRVHLNSQFP-GTERLPNTC------NFSIRGPQLQGRVLLARCRTLLASVGAACHS-----DHTARPSPVLLSCGIPFDVARNALRLSVGRSTTRAEVDLIVQDLKQAVAQ 440          
BLAST of Selenocysteine lyase vs. TrEMBL
Match: A0A3Q7QG46 (selenocysteine lyase isoform X3 OS=Callorhinus ursinus OX=34884 GN=SCLY PE=4 SV=1)

HSP 1 Score: 384.03 bits (985), Expect = 2.618e-126
Identity = 211/434 (48.62%), Postives = 273/434 (62.90%), Query Frame = 1
Query:   85 DSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYD-RYAK-------------IPMIITSTIEHDSISKVLLKMEVDGRI-KLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQ 1320
            D K+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I+ +R +VA MI  +P +IIFTSGGTESNN+V++SVV  F+  R +K              P +IT T+EHDSI ++ L+  V+ R+  +  V +    G +  E +++++   T LVT+MLANNETG++ PI  IS+ ++    K        ILLH+DA QALGK  + V+DLGVD+LTIVGHKFY PRIGALYVR L           L P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + S+FP    RLPNTC      NF+I GP+     +LA+CR L ASVGAACHS  A++      S +L  CG   D+ R+A+RLSVGR T++ +VD  V+DL  AV Q
Sbjct:   29 DRKVYMDYNATTPLEPEVIQAMTEAMREAWGNPSSPYPAGRKAKDIIDTARENVAKMICGKPQDIIFTSGGTESNNLVIHSVVKHFHQTRPSKGSPAELCSPLDGATPHLITCTVEHDSI-RLPLEHLVEERVAAVTFVPVSKVNGQVEAEDILAAVRPATCLVTIMLANNETGVVMPISEISQRIKALNQKRTASGLPVILLHTDAAQALGKRRVDVEDLGVDFLTIVGHKFYGPRIGALYVRGL---------GELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTRNCEAYEAHMRDVRDYLEERLEAEFDKQRIHLNSQFP-GTERLPNTC------NFSIQGPQLQGHAVLARCRALLASVGAACHSDHADRP-----SPVLLSCGIPFDVARNALRLSVGRSTTRAEVDLIVQDLKQAVAQ 440          
BLAST of Selenocysteine lyase vs. TrEMBL
Match: A0A5F4BX04 (Selenocysteine lyase OS=Canis lupus familiaris OX=9615 GN=SCLY PE=4 SV=1)

HSP 1 Score: 384.03 bits (985), Expect = 2.674e-126
Identity = 207/429 (48.25%), Postives = 265/429 (61.77%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAK--------------IPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            K+YMDYNATTPL+P+VI  +   M   W NPSS Y AG  AK  I+ +R ++A MI  +P +IIFTSGGTESNN+V++SVV  F+  +A               +P +IT T+EHDSI   L  +  +    +  V +    G + +E +++++   T LVT+MLANNETG+I PI  IS+ ++    K        ILLH+DA QALGK  + V+DLGVD LTIVGHKFY PRIGALY+R L           L P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  L  +F      + SRFP    RLPNTC      NF+I GP+     +LA+CR L ASVGAACHS  A++      S +L  CG   D+ R+A+RLSVGR T++ DVD  V DL  AV
Sbjct:   36 KVYMDYNATTPLEPEVIQAMTEAMREAWGNPSSPYPAGRKAKDIIDTARENIAKMIGGKPQDIIFTSGGTESNNLVIHSVVKHFHLTHASEGTRAEPSGPLAGAVPHLITCTVEHDSIRLPLEHLLEEQVAAVTFVPVSKVNGQVEVEDILAAVRPATCLVTIMLANNETGVIMPISEISQRIKALNQKRAASGLPVILLHTDAAQALGKQRVDVEDLGVDLLTIVGHKFYGPRIGALYIRGL---------GELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTKNCEAYEAHMRDVRDYLEERLEAEFDKQRIHLNSRFP-GTERLPNTC------NFSIRGPQLQGRLVLAQCRTLLASVGAACHSDHADR-----PSPVLLSCGIPFDVARNALRLSVGRSTTRADVDVVVRDLKQAV 443          
BLAST of Selenocysteine lyase vs. TrEMBL
Match: M3WQG4 (Selenocysteine lyase OS=Felis catus OX=9685 GN=SCLY PE=4 SV=1)

HSP 1 Score: 383.259 bits (983), Expect = 5.187e-126
Identity = 204/426 (47.89%), Postives = 269/426 (63.15%), Query Frame = 1
Query:   73 NKMNDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDF-YDRYAK----IPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPE-----ILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            N   + K+YMDYNATTPL+P+VI  +   M   W NPSS Y  G  AK  I+ +R+ +A MI  +P +IIFTSGGTESNN+V++SVV  F + R A+    +P ++T T+EHDSI   L  +  +    +  V +   +G + +E +++++   T LVTVMLANNETG+I PI  IS+ ++    K        +L+H+DA QALGK  + V+ LGVD+LTIVGHKFY PRIGALY+R L           L P+  M +GGGQERNFR GTENTPMI GLGKAAELV+ N + Y  HM+ +RDYLE  LL +F      + SRFP    RLPNTC      NF+I GP+     +LA+CR L ASVGAACHS   ++      S +L  CG   D+ R+A+RLSVGR T++ +VD  V+DL  AV
Sbjct:   25 NTPPERKVYMDYNATTPLEPEVIQVMTEAMREAWGNPSSPYPTGKKAKDIIDTARDSLAKMIGGKPQDIIFTSGGTESNNLVIHSVVQHFQHTRSAEGDGAVPHLVTCTVEHDSIRLPLEHLVKEQVAAVTFVPVSKVSGQVEVEDILAAVRPATCLVTVMLANNETGVIMPIAEISQRIKALNRKRAASGLPVVLVHTDAAQALGKRRVDVEALGVDFLTIVGHKFYGPRIGALYIRGL---------GELTPLYPMLFGGGQERNFRPGTENTPMIAGLGKAAELVTKNCEAYEAHMRDVRDYLEERLLAEFDKQRIHLNSRFP-GTERLPNTC------NFSIRGPQLQGRVLLAQCRTLLASVGAACHSDQVDRP-----SPVLLSCGIPFDVARNALRLSVGRSTTRAEVDLVVQDLKQAV 429          
BLAST of Selenocysteine lyase vs. Ensembl Cavefish
Match: scly (selenocysteine lyase [Source:NCBI gene;Acc:103029734])

HSP 1 Score: 347.821 bits (891), Expect = 1.408e-115
Identity = 190/424 (44.81%), Postives = 257/424 (60.61%), Query Frame = 1
Query:   91 KIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAK----------------IPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            +IYMDYNATTP+DP+VI  +   +   W NPSS+Y  G  AK  I  +R  +A MI  +  +IIFTSGGTE+NNMV +S ++ F+   A                 +P IITS +EHDSI      +   G+  +  + +   TG + ++ ++++L   T LV+VMLANNETG+I PIR I + ++    +     ++LLH+DA QA+GKI +   +LGVDY+TIVGHKFYA RIGALYV             S  P+  + +GGGQERNFR GTENTPMI GLGKAAELV+ N+ +   H+  IR YLE  LL  F        S FP + + LPNTCNV+++    + G  +L+ CRRL ASVGAACHS   ++      S IL +CG +  +  +A+R+SVGR T++ DVD  VEDL  AV
Sbjct:   32 RIYMDYNATTPVDPEVISAVTDALHHAWGNPSSTYLPGAKAKDIITQARGSIATMIGGKAADIIFTSGGTEANNMVFHSALELFWSSRASAEGGREENHQLNGNKVLPHIITSNVEHDSIINAAEHLLKSGKADVTFLPVSKMTGRVEVDDVMAALRPSTCLVSVMLANNETGVIMPIRDICQKVRSAV-RPSSSPRVLLHTDAAQAIGKIKVDARELGVDYMTIVGHKFYATRIGALYVNG---------PGSTTPLYPLLFGGGQERNFRPGTENTPMIAGLGKAAELVTSNLAVDEAHLLDIRLYLEQRLLAVFGKEKIHFNSHFPGTET-LPNTCNVSIMGQ-GLQGRRVLSTCRRLLASVGAACHSGRGDQ-----PSHILLNCGIAYHVAANALRISVGRATTRKDVDLVVEDLKEAV 438          
BLAST of Selenocysteine lyase vs. Ensembl Cavefish
Match: nfs1 (NFS1 cysteine desulfurase [Source:NCBI gene;Acc:103043755])

HSP 1 Score: 211.075 bits (536), Expect = 1.059e-62
Identity = 144/421 (34.20%), Postives = 218/421 (51.78%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESA------SRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSM 1332
            +YMD+ ATTP+DP+V+D +L      + NP S   A G  +++A+E +R  VA++I A+P EI+FTSG TESNNM +  V   FY   A+   +IT+  EH  +      +E +G   +  + + S  G I++++L+ ++  DT+LV+VM  NNE G+ QPI+ I    +           +  H+DA QA+GKI I+V +L VD ++I GHK Y P+ +GAL+VR              + I+ +  GGGQER  RSGT  TP+ VGLG A EL     +M Y H +     L T L++       KI++  P+         R P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD   E     V +   M
Sbjct:   55 LYMDFQATTPMDPRVLDAMLPYQVNYYGNPHSRTHAYGWESETAMEKARKQVADLIGADPREIVFTSGATESNNMSIKGVA-RFYK--ARKKHVITTQTEHKCVLDSCRVLESEG-FDVTYMPVKS-NGLIDLQQLVETIRPDTSLVSVMTVNNEIGVKQPIKEIGTICR--------SKNVFFHTDAAQAVGKIPINVSELKVDLMSISGHKIYGPKGVGALFVRR----------RPRVRIEPLQSGGGQERGLRSGTVPTPLAVGLGAACELA--QQEMEYDHARV--SMLATRLVQ-------KIMTEIPDVVMNGDPDQRYPGCINLSFAY---VEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAEKCIQQVRRLREM 432          
BLAST of Selenocysteine lyase vs. Ensembl Cavefish
Match: nfs1 (NFS1 cysteine desulfurase [Source:NCBI gene;Acc:103043755])

HSP 1 Score: 206.453 bits (524), Expect = 1.013e-60
Identity = 143/432 (33.10%), Postives = 219/432 (50.69%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINID-MYYFHMKKIRDYLETSLL------RKFSMYGC----KILSRFPESA------SRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSM 1332
            +YMD+ ATTP+DP+V+D +L      + NP S   A G  +++A+E +R  VA++I A+P EI+FTSG TESNNM +  V   FY   A+   +IT+  EH  +      +E +G   +  + + S  G I++++L+ ++  DT+LV+VM  NNE G+ QPI+ I    +           +  H+DA QA+GKI I+V +L VD ++I GHK Y P+ +GAL+VR              + I+ +  GGGQER  RSGT  TP+ VGLG A EL    ++ ++    K  +  L    L       + SM       KI++  P+         R P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD   E     V +   M
Sbjct:   55 LYMDFQATTPMDPRVLDAMLPYQVNYYGNPHSRTHAYGWESETAMEKARKQVADLIGADPREIVFTSGATESNNMSIKGVA-RFYK--ARKKHVITTQTEHKCVLDSCRVLESEG-FDVTYMPVKS-NGLIDLQQLVETIRPDTSLVSVMTVNNEIGVKQPIKEIGTICR--------SKNVFFHTDAAQAVGKIPINVSELKVDLMSISGHKIYGPKGVGALFVRR----------RPRVRIEPLQSGGGQERGLRSGTVPTPLAVGLGAACELAQQEMEQVFLLGGKTCKAKLTKQKLFICYDHARVSMLATRLVQKIMTEIPDVVMNGDPDQRYPGCINLSFA---YVEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAEKCIQQVRRLREM 454          
BLAST of Selenocysteine lyase vs. Ensembl Cavefish
Match: nfs1 (NFS1 cysteine desulfurase [Source:NCBI gene;Acc:103043755])

HSP 1 Score: 192.2 bits (487), Expect = 1.035e-55
Identity = 135/398 (33.92%), Postives = 205/398 (51.51%), Query Frame = 1
Query:  127 DPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESA------SRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVE 1296
            DP+V+D +L      + NP S   A G  +++A+E +R  VA++I A+P EI+FTSG TESNNM +  V   FY   A+   +IT+  EH  +      +E +G   +  + + S  G I++++L+ ++  DT+LV+VM  NNE G+ QPI+ I    +           +  H+DA QA+GKI I+V +L VD ++I GHK Y P+ +GAL+VR              + I+ +  GGGQER  RSGT  TP+ VGLG A EL     +M Y H +     L T L++       KI++  P+         R P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ +VD   E
Sbjct:   42 DPRVLDAMLPYQVNYYGNPHSRTHAYGWESETAMEKARKQVADLIGADPREIVFTSGATESNNMSIKGVA-RFYK--ARKKHVITTQTEHKCVLDSCRVLESEG-FDVTYMPVKS-NGLIDLQQLVETIRPDTSLVSVMTVNNEIGVKQPIKEIGTICR--------SKNVFFHTDAAQAVGKIPINVSELKVDLMSISGHKIYGPKGVGALFVRR----------RPRVRIEPLQSGGGQERGLRSGTVPTPLAVGLGAACELA--QQEMEYDHARV--SMLATRLVQ-------KIMTEIPDVVMNGDPDQRYPGCINLSFAY---VEGESLLMALKDVALSSGSACTSASLEP------SYVLRAIGTDEDLAHSSIRFGIGRFTTEEEVDYTAE 396          
BLAST of Selenocysteine lyase vs. Ensembl Sea Lamprey
Match: scly (selenocysteine lyase [Source:ZFIN;Acc:ZDB-GENE-080204-30])

HSP 1 Score: 194.126 bits (492), Expect = 1.028e-59
Identity = 94/204 (46.08%), Postives = 132/204 (64.71%), Query Frame = 1
Query:  349 RYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQ--NKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKK 954
            R A +P II S +EHDS+   +  +  +GR     V     TG + ++++++++   T +V++MLANNETGII P+  I + ++            ++LLH+DA QALGKI ++V++LGVDYLT+VGHKFY PR+GAL VR L          +  P+  M +GGGQERNFR GTENTPMI GLGKAAELV  ++D Y  HM++
Sbjct:   24 RGAALPHIIVSCLEHDSVRLAVDSLVAEGRADFTAVPASWVTGRVEVDQVLAAIRPTTCIVSIMLANNETGIIMPVAEICRRVRAMRGGGAMPRLGRVLLHTDAAQALGKIRVNVEELGVDYLTVVGHKFYGPRVGALCVRGL---------GAGTPLVPMLFGGGQERNFRPGTENTPMIAGLGKAAELVCQHLDEYERHMRQ 218          
BLAST of Selenocysteine lyase vs. Ensembl Sea Lamprey
Match: NFS1 (NFS1 cysteine desulfurase [Source:HGNC Symbol;Acc:HGNC:15910])

HSP 1 Score: 89.3521 bits (220), Expect = 1.656e-21
Identity = 50/144 (34.72%), Postives = 85/144 (59.03%), Query Frame = 1
Query:  331 VDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALY 759
            V  FY +  +   ++T+  EH  +      +E +G  ++  + + S  G +++++L ++L  DT LV+VM  NNE G+ QPIR I +  +        Q+K+  H+DA QA+GKI I V+D+ +D ++I GHK Y P+ +GA+Y
Sbjct:    5 VARFYKQRKR--HVLTTQTEHKCVLDSCRALEAEG-FEVTYLPVQS-NGLVDMKELEAALRPDTCLVSVMAVNNEIGVKQPIREIGELCR--------QHKVFFHTDAAQAIGKIPIDVNDMKIDLMSISGHKIYGPKGVGAIY 136          
BLAST of Selenocysteine lyase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005417.1 (pep scaffold:Pmarinus_7.0:GL488863:118:7342:1 gene:ENSPMAG00000004932.1 transcript:ENSPMAT00000005417.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 43.5134 bits (101), Expect = 2.188e-6
Identity = 20/49 (40.82%), Postives = 32/49 (65.31%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKA-GMVAKSAIEDSR 237
            +YMD  ATTP+DP+V+D ++  M   + NP S   A G  +++A+E +R
Sbjct:    4 LYMDVQATTPMDPRVVDAMMPHMLGKYGNPHSRTHAYGWESEAAVEKAR 52          
BLAST of Selenocysteine lyase vs. Ensembl Yeast
Match: NFS1 (Cysteine desulfurase; involved in iron-sulfur cluster (Fe/S) biogenesis and in thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria [Source:SGD;Acc:S000000522])

HSP 1 Score: 218.009 bits (554), Expect = 1.129e-65
Identity = 147/410 (35.85%), Postives = 215/410 (52.44%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNP-SSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDG-RIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            IY+D  ATTP DP+V+D +L   +  + NP S+++  G    +A+E++R HVA MI A+P EIIFTSG TESNNMVL   V  FY +  K   IIT+  EH  + +    M  +G  +    V+     G I++++L  ++  DT LV+VM  NNE G+IQPI+ I    +        +NKI  H+DA QA GKI I V+++ +D L+I  HK Y P+ IGA+YVR              + ++ +  GGGQER  RSGT   P++ G G+AA L+    D    H+K++ D L   LL          L+  P+   R P   NV+      + G  +L   R +  S G+AC S           S +L   G    L  S+IR  +GR +++ +VD  V+ + + V
Sbjct:  100 IYLDMQATTPTDPRVLDTMLKFYTGLYGNPHSNTHSYGWETNTAVENARAHVAKMINADPKEIIFTSGATESNNMVLKG-VPRFYKKTKK--HIITTRTEHKCVLEAARAMMKEGFEVTFLNVD---DQGLIDLKELEDAIRPDTCLVSVMAVNNEIGVIQPIKEIGAICR--------KNKIYFHTDAAQAYGKIHIDVNEMNIDLLSISSHKIYGPKGIGAIYVRR----------RPRVRLEPLLSGGGQERGLRSGTLAPPLVAGFGEAARLMKKEFDNDQAHIKRLSDKLVKGLLSAEHT----TLNGSPD--HRYPGCVNVSFAY---VEGESLLMALRDIALSSGSACTSASLEP------SYVLHALGKDDALAHSSIRFGIGRFSTEEEVDYVVKAVSDRV 470          
BLAST of Selenocysteine lyase vs. Ensembl Nematostella
Match: EDO30645 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T075])

HSP 1 Score: 350.903 bits (899), Expect = 1.158e-117
Identity = 200/417 (47.96%), Postives = 257/417 (61.63%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDR--------YAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQN--KILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            IY+DYNATTPLDP V++ I   +   W NPSSS+  G  A   I+ SR  +A MI A  +EIIFTSGGTESNNMV+++ ++ +  +           IP IITS  EHDS+   L ++E + +I+L  V +   +G +  + ++ ++  +T LV++MLANNETGIIQPI  I K+LQ    K        IL H+DA QALGKI + V DL VDYLTIVGHKFY PRIGALYVR+L     +       P+  MF+GGGQERN+R GTENT MI GLG+AA+LV  ++  Y  HM+ +RDYLE SL  KF      I  RF  ++ RLPNTCNV+ + +  + G  IL     L ASVGAACHS    K      S IL   G    +  +A+R+SVGRETSK D+D  V DL  AV
Sbjct:    2 IYLDYNATTPLDPTVLESIHNALQNAWGNPSSSHHFGSEANGIIKRSRASIAKMINAHNSEIIFTSGGTESNNMVIHTAIEHYKKQRETTGKAILPPIPHIITSNQEHDSVCLPLKQLEAESKIELGVVHVSKSSGMVMPDAVMDAIRPNTCLVSLMLANNETGIIQPISEIFKSLQSIQKKRSEAGLPTILTHTDAAQALGKIPVDVLDLDVDYLTIVGHKFYGPRIGALYVRSLGEPSGR-------PLYPMFFGGGQERNYRPGTENTGMIAGLGQAAQLVVDHLYEYQEHMENVRDYLEASLTEKFGKECIHINGRF-STSKRLPNTCNVSFIGD-GLHGRTILKTVNHLLASVGAACHSDRVAK-----PSHILLALGIPDKVAMNAVRMSVGRETSKQDIDVVVTDLKTAV 404          
BLAST of Selenocysteine lyase vs. Ensembl Nematostella
Match: EDO32544 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SUT0])

HSP 1 Score: 184.111 bits (466), Expect = 1.486e-53
Identity = 125/395 (31.65%), Postives = 210/395 (53.16%), Query Frame = 1
Query:  124 LDPKVIDRIL-YTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDL 1302
            +DP+V+D ++ YT+SF  +  S +++ G  ++ A+E +R  VAN+I A+P E+IFTSG TESNN+ +   V  FY +  K   IIT+  EH  +      +E +G  ++  + + +K G ++I+K   +L   T++ ++M+ NNE G+IQPI  +    +        +NK+  H+DA QA+GKI + V+++ +D ++I  HK Y P+ IGALYVR       +       PI+S   GGGQER  RSGT    + VGLG A E+    ++     ++ + + L   +++  S      + R  +  +  P   N++      + G  +L   + +  S G+AC S           S +L+  G   DL  S+IR  +GR T++ ++D  VE +
Sbjct:    1 MDPRVVDAMMPYTVSFYGNPHSRTHQYGWESEKAVEKAREQVANLIGADPKEVIFTSGATESNNIAIKG-VGRFYKK--KKNHIITAQTEHKCVLDSCRVLEGEG-FEVDYLGV-NKNGLVDIKKFEKALRPTTSMASIMMVNNEIGVIQPIAELGALCR--------KNKVFFHTDAAQAIGKIPVDVNEMNIDLMSISAHKIYGPKGIGALYVRRRPRVRVE-------PIQS---GGGQERGMRSGTVPHVLCVGLGAACEVAQQEMEYDKKRIEMLSERLINGIMKSVSH-----VVRNGDPINAYPGCVNLSFAY---VEGESLLMALKDIALSSGSACTSASLEP------SYVLRAIGAEEDLAHSSIRFGIGRFTTEEEIDYTVEKI 358          
BLAST of Selenocysteine lyase vs. Ensembl Nematostella
Match: EDO25341 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8DWR9])

HSP 1 Score: 150.984 bits (380), Expect = 9.288e-42
Identity = 95/305 (31.15%), Postives = 166/305 (54.43%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAIN---IEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFS 996
            IY+D  ATTP+D +VI+ +  +M  N  NPSS ++ G  AK+++E +R ++A     + +EIIFT+GGTE++N++L++ V +       + +IITS IEH ++   +  ++    I++  VEI  + G+IN   +E+L+++      LV++M  NNE G + P+ ++    ++Y        K L HSD  QA+G   I +    +D++    HKF+ P+ +G  Y +              + I+ M +GG QE+  RS TEN   I+G+ KA  +   NI+    ++  ++ Y   +L   F+
Sbjct:    4 IYLDNAATTPIDKEVIEVMHQSMLENNGNPSSIHQVGRKAKASVETARKNIAKYFNVDASEIIFTAGGTEADNLILHNAVTNL-----GVEVIITSKIEHHAVLHTVAYLQEQYSIEVLFVEI-DEDGSINLKHLEQLLAANTNKQCLVSLMYVNNEIGNLLPLDAVCGLCEKY--------KALFHSDTVQAIGHYPIDLQKTPIDFMAASAHKFHGPKGVGFAYFK------------KGVGIQPMLHGGNQEKGARSSTENVHSILGMEKALAIAITNIEKDANYLTSLKKYFIDALTVNFN 282          
BLAST of Selenocysteine lyase vs. Ensembl Medaka
Match: scly (selenocysteine lyase [Source:NCBI gene;Acc:101165796])

HSP 1 Score: 354.755 bits (909), Expect = 6.572e-119
Identity = 191/418 (45.69%), Postives = 266/418 (63.64%), Query Frame = 1
Query:  100 MDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAK-------------IPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAV 1314
            MDYNATTPL+P+V+  +   +   W NPSS++ AG  AK+ I  SR  VA M+  +  +IIFTSGGTE+NN+VL++ V+ F                   +P IITS IEHDSI +V   ++ +G+ ++  V +   +G I +E +I+++  +T L++VMLANNETG+I P++ I + ++ + +K + + +ILLH+DA QALGKI + V +LGVDYLTIVGHKFYAPRIGAL+V             S  P+  M +GGGQERNFR GTENTPMI GLGKA+ELV++N+  Y  HM+ I+ YLE  +   F     +  +RFP S   LPNT N++++    + G  +L+ CRRL ASVGAACHS   N+      S IL  CG   ++  +A+R+SVGR T+K +VD  VEDL   V
Sbjct:    1 MDYNATTPLEPEVLQAVSTALQDAWGNPSSNHIAGATAKAIIYQSRQSVARMVGGKAEDIIFTSGGTEANNLVLHTAVEYFQKNCGAAEQGEGLQNGCRGLPHIITSNIEHDSIQQVASHLQKEGKAEVTFVPVSRVSGCIEVEDVIAAVRPNTCLISVMLANNETGVIMPLQEICQRVK-FLNKQRERLRILLHTDAAQALGKIPVDVQELGVDYLTIVGHKFYAPRIGALFVNG---------PGSRTPLYPMLFGGGQERNFRPGTENTPMIAGLGKASELVTLNLSEYSSHMQSIKLYLEEQMESVFRDK-IRFNNRFPGS-DILPNTINMSIL-GPTLQGWRVLSTCRRLLASVGAACHSASGNR-----PSHILLSCGVPTEVAANALRVSVGRGTTKAEVDAVVEDLRETV 400          
BLAST of Selenocysteine lyase vs. Planmine SMEST
Match: SMESG000035935.1 (SMESG000035935.1)

HSP 1 Score: 851.277 bits (2198), Expect = 0.000e+0
Identity = 411/412 (99.76%), Postives = 411/412 (99.76%), Query Frame = 1
Query:  100 MDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSMI 1335
            MDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFY PRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSMI
Sbjct:    1 MDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYGPRIGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSMI 412          
BLAST of Selenocysteine lyase vs. Planmine SMEST
Match: SMESG000021651.1 (SMESG000021651.1)

HSP 1 Score: 201.06 bits (510), Expect = 2.866e-59
Identity = 137/417 (32.85%), Postives = 220/417 (52.76%), Query Frame = 1
Query:   94 IYMDYNATTPLDPKVIDRILYTMSFNWHNP-SSSYKAGMVAKSAIEDSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIITSTIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTALVTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKIDISVDDLGVDYLTIVGHKFYAPR-IGALYVRNLHLNEKQIICDSLIPIKSMFYGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETSLLRKFS--MYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLDVDDAVEDLHNAVLQYLSM 1332
            +YMD  ATTP+DP+V+D ++      + NP S S+  G  +++A+E +R  VAN+I A   EIIFTSG TESNN+ L  V   FY    K   IIT+  EH  +      +  +G  ++  + + S+ G I++++L  ++  DT +V++M  NNE G++QPI+ I +  +          K+  H+DA QA+GKI ++VDD+ +D ++I GHK Y P+ IGALYVR              + I+++  GGGQER  RSGT  + + VGLG A EL    +D     +K++ D L+  +  +    ++   +++ +       P   N++    F + G  +L + + +  S G+AC S           S +L+  G   DL  S+IR  +GR T+  ++D  V+     V Q   M
Sbjct:   31 LYMDNQATTPIDPRVLDAMMPFYLDMFGNPHSRSHAYGWESEAAVEKARKQVANLIGANEKEIIFTSGATESNNIALKGVA-RFYK--GKKNHIITTQTEHKCVLDSCRLLSYEG-FEISYMPVDSQ-GLIDLKELEKAIRPDTTMVSIMTVNNEIGVLQPIKEIGEICR--------AKKVFFHTDAAQAVGKIKLNVDDMKIDLMSISGHKIYGPKGIGALYVRR----------RPRVRIEAIQSGGGQERGMRSGTLPSTLCVGLGAACELAESEMDYDKERVKQLSDRLKNGISSQLDHIVFNGDLINGY-------PGCVNISF--GF-VEGESLLMQLKDIALSSGSACTS------QSLEPSYVLRAIGTKEDLAHSSIRFGIGRFTTVEEIDYTVKKCVEKVKQLRKM 408          
The following BLAST results are available for this feature:
BLAST of Selenocysteine lyase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
SCLY2.315e-12246.08selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:... [more]
SCLY2.741e-12246.08selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:... [more]
SCLY1.170e-8146.71selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:... [more]
SCLY1.259e-7150.21selenocysteine lyase [Source:HGNC Symbol;Acc:HGNC:... [more]
NFS12.560e-6133.00NFS1 cysteine desulfurase [Source:HGNC Symbol;Acc:... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 2
Match NameE-valueIdentityDescription
F13H8.98.113e-8539.80pep chromosome:WBcel235:II:6279676:6281102:-1 gene... [more]
B0205.63.075e-6031.76pep chromosome:WBcel235:I:10736697:10739911:1 gene... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Nfs12.013e-5935.00gene:FBgn0032393 transcript:FBtr0080290[more]
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BLAST of Selenocysteine lyase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3
Match NameE-valueIdentityDescription
scly9.136e-11544.42selenocysteine lyase [Source:ZFIN;Acc:ZDB-GENE-080... [more]
nfs15.879e-6035.12NFS1 cysteine desulfurase [Source:ZFIN;Acc:ZDB-GEN... [more]
scly1.161e-1550.70selenocysteine lyase [Source:ZFIN;Acc:ZDB-GENE-080... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
scly3.526e-12950.36selenocysteine lyase [Source:NCBI gene;Acc:496582][more]
scly1.010e-12850.24selenocysteine lyase [Source:NCBI gene;Acc:496582][more]
scly1.609e-11947.73selenocysteine lyase [Source:NCBI gene;Acc:496582][more]
scly3.233e-11346.56selenocysteine lyase [Source:NCBI gene;Acc:496582][more]
ncdn2.960e-5933.17neurochondrin [Source:Xenbase;Acc:XB-GENE-968620][more]
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BLAST of Selenocysteine lyase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Scly8.792e-12345.73selenocysteine lyase [Source:MGI Symbol;Acc:MGI:13... [more]
Nfs14.142e-6233.17nitrogen fixation gene 1 (S. cerevisiae) [Source:M... [more]
Scly1.703e-5542.06selenocysteine lyase [Source:MGI Symbol;Acc:MGI:13... [more]
Scly1.024e-4039.02selenocysteine lyase [Source:MGI Symbol;Acc:MGI:13... [more]
Scly1.158e-3939.20selenocysteine lyase [Source:MGI Symbol;Acc:MGI:13... [more]
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BLAST of Selenocysteine lyase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q5U4Q9|SCLY_XENTR5.349e-12850.24Selenocysteine lyase OS=Xenopus tropicalis OX=8364... [more]
sp|Q66IQ6|SCLY_XENLA5.163e-12648.60Selenocysteine lyase OS=Xenopus laevis OX=8355 GN=... [more]
sp|A2VDS1|SCLY_BOVIN8.042e-12547.09Selenocysteine lyase OS=Bos taurus OX=9913 GN=SCLY... [more]
sp|Q9JLI6|SCLY_MOUSE4.041e-12345.96Selenocysteine lyase OS=Mus musculus OX=10090 GN=S... [more]
sp|Q68FT9|SCLY_RAT3.694e-12246.50Selenocysteine lyase OS=Rattus norvegicus OX=10116... [more]
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BLAST of Selenocysteine lyase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2U3WN644.973e-12748.85selenocysteine lyase OS=Odobenus rosmarus divergen... [more]
A0A2Y9G6J39.854e-12748.85selenocysteine lyase OS=Neomonachus schauinslandi ... [more]
A0A3Q7QG462.618e-12648.62selenocysteine lyase isoform X3 OS=Callorhinus urs... [more]
A0A5F4BX042.674e-12648.25Selenocysteine lyase OS=Canis lupus familiaris OX=... [more]
M3WQG45.187e-12647.89Selenocysteine lyase OS=Felis catus OX=9685 GN=SCL... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4
Match NameE-valueIdentityDescription
scly1.408e-11544.81selenocysteine lyase [Source:NCBI gene;Acc:1030297... [more]
nfs11.059e-6234.20NFS1 cysteine desulfurase [Source:NCBI gene;Acc:10... [more]
nfs11.013e-6033.10NFS1 cysteine desulfurase [Source:NCBI gene;Acc:10... [more]
nfs11.035e-5533.92NFS1 cysteine desulfurase [Source:NCBI gene;Acc:10... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 3
Match NameE-valueIdentityDescription
scly1.028e-5946.08selenocysteine lyase [Source:ZFIN;Acc:ZDB-GENE-080... [more]
NFS11.656e-2134.72NFS1 cysteine desulfurase [Source:HGNC Symbol;Acc:... [more]
ENSPMAT00000005417.12.188e-640.82pep scaffold:Pmarinus_7.0:GL488863:118:7342:1 gene... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
NFS11.129e-6535.85Cysteine desulfurase; involved in iron-sulfur clus... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 3
Match NameE-valueIdentityDescription
EDO306451.158e-11747.96Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO325441.486e-5331.65Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO253419.288e-4231.15Predicted protein [Source:UniProtKB/TrEMBL;Acc:A8... [more]
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BLAST of Selenocysteine lyase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
scly6.572e-11945.69selenocysteine lyase [Source:NCBI gene;Acc:1011657... [more]
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BLAST of Selenocysteine lyase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000035935.10.000e+099.76SMESG000035935.1[more]
SMESG000021651.12.866e-5932.85SMESG000021651.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035128 ID=SMED30035128|Name=Selenocysteine lyase|organism=Schmidtea mediterranea sexual|type=transcript|length=1418bp
ATTTAAATAAGCATGTCTTATGTTTTTGCTACTTTATAAATACTTATTTA
ATTTAATTATACTTATTAAATTAACAAAATGAACGATAGCAAAATATATA
TGGATTACAATGCCACGACTCCTCTTGATCCAAAAGTTATTGACAGAATT
CTATATACAATGAGTTTTAACTGGCACAATCCAAGTAGCTCTTACAAAGC
CGGCATGGTAGCTAAATCGGCAATCGAAGATTCACGCAATCACGTAGCTA
ATATGATTAAGGCTGAGCCAAATGAAATAATTTTCACATCTGGTGGTACA
GAGTCCAATAATATGGTTTTAAATTCGGTCGTCGATGACTTTTATGACAG
ATATGCTAAAATACCTATGATTATCACATCGACAATTGAGCATGACTCAA
TTTCAAAGGTTCTTTTGAAAATGGAAGTCGACGGTCGAATAAAATTGAAG
CAAGTAGAAATCTGTTCCAAAACAGGCGCTATAAATATCGAAAAATTAAT
CAGCAGTCTTAATGAAGATACAGCTTTAGTAACTGTAATGCTTGCCAACA
ACGAAACTGGCATTATTCAGCCCATTCGATCTATTTCAAAAGCACTACAA
GAATATACTGATAAGCATCAATTTCAAAACAAAATACTTTTGCATTCTGA
TGCAGGACAGGCTCTAGGCAAAATTGATATCTCAGTTGATGATCTTGGAG
TTGATTATCTGACAATTGTAGGCCATAAGTTTTATGCTCCTCGAATAGGA
GCATTGTACGTTCGAAATTTACATTTAAATGAAAAGCAAATTATTTGTGA
TTCTCTAATTCCTATTAAGAGTATGTTTTACGGAGGTGGTCAAGAACGCA
ATTTTCGTTCTGGTACAGAAAACACTCCTATGATTGTTGGATTAGGAAAA
GCAGCAGAGTTAGTATCGATAAATATCGATATGTATTATTTTCACATGAA
GAAAATTAGAGATTATCTAGAAACAAGTCTTTTAAGGAAATTTTCAATGT
ATGGATGTAAGATTCTTTCTCGATTTCCCGAATCTGCTAGTCGATTGCCA
AATACTTGCAACGTCGCTCTTGTAACGAATTTTAATATAACAGGGCCAGA
AATTCTTGCAAAGTGTAGAAGACTCCAAGCAAGTGTGGGAGCCGCATGTC
ATTCAATAGACGCAAACAAAATACATCTCTATGCGGGCAGTGAAATATTA
AAACATTGTGGTTATTCACTTGATCTTTGCCGTTCTGCAATTCGACTCAG
TGTCGGTCGAGAAACATCAAAGCTTGATGTCGACGATGCTGTCGAAGATC
TCCATAACGCAGTTCTACAGTATTTGTCCATGATCTGAATTTGAACTTTA
TTTTTTGTTTTTCTTTCTTTATTTGTATAATTTATCGCTTAATTTACTCC
AATGTTGATAATTCAATA
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protein sequence of SMED30035128-orf-1

>SMED30035128-orf-1 ID=SMED30035128-orf-1|Name=SMED30035128-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=420bp
MNDSKIYMDYNATTPLDPKVIDRILYTMSFNWHNPSSSYKAGMVAKSAIE
DSRNHVANMIKAEPNEIIFTSGGTESNNMVLNSVVDDFYDRYAKIPMIIT
STIEHDSISKVLLKMEVDGRIKLKQVEICSKTGAINIEKLISSLNEDTAL
VTVMLANNETGIIQPIRSISKALQEYTDKHQFQNKILLHSDAGQALGKID
ISVDDLGVDYLTIVGHKFYAPRIGALYVRNLHLNEKQIICDSLIPIKSMF
YGGGQERNFRSGTENTPMIVGLGKAAELVSINIDMYYFHMKKIRDYLETS
LLRKFSMYGCKILSRFPESASRLPNTCNVALVTNFNITGPEILAKCRRLQ
ASVGAACHSIDANKIHLYAGSEILKHCGYSLDLCRSAIRLSVGRETSKLD
VDDAVEDLHNAVLQYLSMI*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0000418head
Vocabulary: INTERPRO
TermDefinition
IPR000192Aminotrans_V_dom
IPR015421PyrdxlP-dep_Trfase_major
IPR016454Cysteine_dSase
IPR015422PyrdxlP-dep_Trfase_dom1
IPR015424PyrdxlP-dep_Trfase
Vocabulary: molecular function
TermDefinition
GO:0003824catalytic activity
GO:0009000selenocysteine lyase activity
GO:0016740transferase activity
GO:0016829lyase activity
Vocabulary: cellular component
TermDefinition
GO:0005737cytoplasm
GO:0005829cytosol
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR015421Pyridoxal phosphate-dependent transferase, major domainGENE3DG3DSA:3.40.640.10coord: 63..261
e-value: 4.7E-121
score: 406.5
IPR016454Cysteine desulfurasePIRSFPIRSF005572NifScoord: 3..417
e-value: 2.3E-115
score: 383.3
IPR000192Aminotransferase class V domainPFAMPF00266Aminotran_5coord: 6..402
e-value: 6.2E-51
score: 173.5
IPR015422Pyridoxal phosphate-dependent transferase domain 1GENE3DG3DSA:3.90.1150.10coord: 6..408
e-value: 4.7E-121
score: 406.5
NoneNo IPR availableGENE3DG3DSA:1.10.260.50coord: 17..305
e-value: 4.7E-121
score: 406.5
NoneNo IPR availablePANTHERPTHR11601:SF59SELENOCYSTEINE LYASEcoord: 3..412
NoneNo IPR availablePANTHERPTHR11601CYSTEINE DESULFURYLASEcoord: 3..412
IPR015424Pyridoxal phosphate-dependent transferaseSUPERFAMILYSSF53383PLP-dependent transferasescoord: 5..411