Protein kinase
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035101 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 7
Homology
BLAST of Protein kinase vs. Ensembl Human
Match: MAP3K19 (mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]) HSP 1 Score: 132.88 bits (333), Expect = 5.500e-33 Identity = 86/284 (30.28%), Postives = 143/284 (50.35%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + +G YG + S G ++ A+K++ T+ N + + L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYTKQIL+G+++LHEN ++H D+K N++L KL D GC+R + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P H + D + ++ ++RP+A LLK F
Sbjct: 243 WTKGEILGKGAYGTVYCGLTSQG-QLIAVKQVALDTS-NKLAAEKEYRKLQEEVDLLKA---LKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRFGP-LPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRL----------AWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAAD-----FVRMCLTRDQHERPSALQLLKHSF 505
BLAST of Protein kinase vs. Ensembl Human
Match: MAP3K19 (mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]) HSP 1 Score: 131.724 bits (330), Expect = 1.046e-31 Identity = 86/284 (30.28%), Postives = 143/284 (50.35%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + +G YG + S G ++ A+K++ T+ N + + L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYTKQIL+G+++LHEN ++H D+K N++L KL D GC+R + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P H + D + ++ ++RP+A LLK F
Sbjct: 948 WTKGEILGKGAYGTVYCGLTSQG-QLIAVKQVALDTS-NKLAAEKEYRKLQEEVDLLKA---LKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRL----------AWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAAD-----FVRMCLTRDQHERPSALQLLKHSF 1210
BLAST of Protein kinase vs. Ensembl Human
Match: MAP3K19 (mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]) HSP 1 Score: 128.642 bits (322), Expect = 1.183e-31 Identity = 88/285 (30.88%), Postives = 139/285 (48.77%), Query Frame = 1
Query: 646 EFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
EFS GR K+ S G ++ A+K++ T+ N + + L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYTKQIL+G+++LHEN ++H D+K N++L KL D GC+R + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P H + D + ++ ++RP+A LLK F
Sbjct: 192 EFSTSHMKYSGRSIKVYCGLTSQG-QLIAVKQVALDTS-NKLAAEKEYRKLQEEVDLLKA---LKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRL----------AWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAAD-----FVRMCLTRDQHERPSALQLLKHSF 455
BLAST of Protein kinase vs. Ensembl Human
Match: MAP3K19 (mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]) HSP 1 Score: 131.339 bits (329), Expect = 1.215e-31 Identity = 86/284 (30.28%), Postives = 143/284 (50.35%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + +G YG + S G ++ A+K++ T+ N + + L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYTKQIL+G+++LHEN ++H D+K N++L KL D GC+R + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P H + D + ++ ++RP+A LLK F
Sbjct: 1061 WTKGEILGKGAYGTVYCGLTSQG-QLIAVKQVALDTS-NKLAAEKEYRKLQEEVDLLKA---LKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRL----------AWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAAD-----FVRMCLTRDQHERPSALQLLKHSF 1323
BLAST of Protein kinase vs. Ensembl Human
Match: MAP3K19 (mitogen-activated protein kinase kinase kinase 19 [Source:HGNC Symbol;Acc:HGNC:26249]) HSP 1 Score: 131.339 bits (329), Expect = 1.215e-31 Identity = 86/284 (30.28%), Postives = 143/284 (50.35%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + +G YG + S G ++ A+K++ T+ N + + L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYTKQIL+G+++LHEN ++H D+K N++L KL D GC+R + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P H + D + ++ ++RP+A LLK F
Sbjct: 1061 WTKGEILGKGAYGTVYCGLTSQG-QLIAVKQVALDTS-NKLAAEKEYRKLQEEVDLLKA---LKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRL----------AWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAAD-----FVRMCLTRDQHERPSALQLLKHSF 1323
BLAST of Protein kinase vs. Ensembl Celegans
Match: cst-2 (Caenorhabditis STE20-like kinase [Source:UniProtKB/TrEMBL;Acc:Q304D8]) HSP 1 Score: 115.931 bits (289), Expect = 5.976e-28 Identity = 84/298 (28.19%), Postives = 140/298 (46.98%), Query Frame = 1
Query: 619 FCLTSICFNEFSEGQF-----IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F L S N+ E F + G YG + K + AIKK+ T+L ++I KE +++ +KY + KYYG+ K ++I M++ GSI +++ + L ++ + + L+GL +LH+ + IH D+K+ NILL+T+ KL D G + + +++ K + + GT MAPE+I+ + YD KADIWS T EM +G+P ++ + + P +KK E + + S IK+P +R TA L + F
Sbjct: 20 FKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEII----KEISIMQQCKSKY--------VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-----------------TVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKK---PEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTF 285
BLAST of Protein kinase vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31]) HSP 1 Score: 115.931 bits (289), Expect = 1.446e-27 Identity = 84/298 (28.19%), Postives = 140/298 (46.98%), Query Frame = 1
Query: 619 FCLTSICFNEFSEGQF-----IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F L S N+ E F + G YG + K + AIKK+ T+L ++I KE +++ +KY + KYYG+ K ++I M++ GSI +++ + L ++ + + L+GL +LH+ + IH D+K+ NILL+T+ KL D G + + +++ K + + GT MAPE+I+ + YD KADIWS T EM +G+P ++ + + P +KK E + + S IK+P +R TA L + F
Sbjct: 20 FKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEII----KEISIMQQCKSKY--------VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-----------------TVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKK---PEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTF 285
BLAST of Protein kinase vs. Ensembl Celegans
Match: cst-1 (Serine/threonine-protein kinase cst-1 Serine/threonine-protein kinase cst-1 37kDa subunit Serine/threonine-protein kinase cst-1 18kDa subunit [Source:UniProtKB/Swiss-Prot;Acc:Q9NB31]) HSP 1 Score: 115.546 bits (288), Expect = 1.653e-27 Identity = 84/298 (28.19%), Postives = 140/298 (46.98%), Query Frame = 1
Query: 619 FCLTSICFNEFSEGQF-----IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F L S N+ E F + G YG + K + AIKK+ T+L ++I KE +++ +KY + KYYG+ K ++I M++ GSI +++ + L ++ + + L+GL +LH+ + IH D+K+ NILL+T+ KL D G + + +++ K + + GT MAPE+I+ + YD KADIWS T EM +G+P ++ + + P +KK E + + S IK+P +R TA L + F
Sbjct: 20 FKLDSSALNKPPEEVFDIVGKLGEGSYGSVHKAIHRESGHVLAIKKVPVDTDLQEII----KEISIMQQCKSKY--------VVKYYGSYFKHSDLWIVMEYCGAGSISDIMRARRKPLSEQEISAVLRDTLKGLQYLHDLKKIHRDIKAGNILLNTDGIAKLADFGVAGQLTDTMAKRN-----------------TVIGTPFWMAPEVIEEIGYDTKADIWSLGITAIEMAEGRPPYSDIHPMRAIFMIPTKPPPTFKK---PEEWSSEFNDFIRSCLIKKPEERKTALRLCEHTF 285
BLAST of Protein kinase vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 112.849 bits (281), Expect = 3.459e-26 Identity = 82/284 (28.87%), Postives = 141/284 (49.65%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYT-KQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F++ + I RG +G++ K + R+ AIK I+ + D IE++++E ++ ++Y +TKY+G+ +KG K++I M++ GGS +L + G DE + ++IL+GL +LH R IH D+K+ N+L+ + K+ D G + + E++ K + G+ MAPE+I+ SYD KADIWS T E+ +G+P + VL + K P + + + ++ K+P RP+A LLK F
Sbjct: 34 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLE-QAEDEIEDIQQEIQVLSQCDSQY--------VTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS---GKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRI-----------------TFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSK----PFKEFVEMCLNKDPENRPSASTLLKHQF 284
BLAST of Protein kinase vs. Ensembl Celegans
Match: gck-1 (Germinal center kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:H2L099]) HSP 1 Score: 113.235 bits (282), Expect = 3.526e-26 Identity = 82/284 (28.87%), Postives = 141/284 (49.65%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYT-KQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F++ + I RG +G++ K + R+ AIK I+ + D IE++++E ++ ++Y +TKY+G+ +KG K++I M++ GGS +L + G DE + ++IL+GL +LH R IH D+K+ N+L+ + K+ D G + + E++ K + G+ MAPE+I+ SYD KADIWS T E+ +G+P + VL + K P + + + ++ K+P RP+A LLK F
Sbjct: 184 FTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLE-QAEDEIEDIQQEIQVLSQCDSQY--------VTKYFGSFLKGSKLWIIMEYLGGGSALDLTKS---GKLDESHIAVILREILKGLEYLHSERKIHRDIKAANVLVSEHGDVKVADFGVAGQLTETVKKRI-----------------TFVGSPFWMAPELIKQSSYDYKADIWSLGITAIELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSK----PFKEFVEMCLNKDPENRPSASTLLKHQF 434
BLAST of Protein kinase vs. Ensembl Fly
Match: hpo (gene:FBgn0261456 transcript:FBtr0331920) HSP 1 Score: 114.39 bits (285), Expect = 1.437e-26 Identity = 75/277 (27.08%), Postives = 133/277 (48.01%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G YG + K S I AIK + +++L+++I KE +++ + Y + +YYG+ K Y ++I M++ GS+ +++ + L ++ + L+GL +LH R IH D+K+ NILL+TE KL D G + + +++ K + + GT MAPE+I+ + YD ADIWS T EM +G+P + + + + P +++ + + I + +KEP+ R TA LL+ F
Sbjct: 48 LGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEII----KEISIMQQCDSPY--------VVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRN-----------------TVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFRE---PDRWSTEFIDFVSKCLVKEPDDRATATELLEHEF 292
BLAST of Protein kinase vs. Ensembl Fly
Match: hpo (gene:FBgn0261456 transcript:FBtr0086500) HSP 1 Score: 114.39 bits (285), Expect = 1.437e-26 Identity = 75/277 (27.08%), Postives = 133/277 (48.01%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G YG + K S I AIK + +++L+++I KE +++ + Y + +YYG+ K Y ++I M++ GS+ +++ + L ++ + L+GL +LH R IH D+K+ NILL+TE KL D G + + +++ K + + GT MAPE+I+ + YD ADIWS T EM +G+P + + + + P +++ + + I + +KEP+ R TA LL+ F
Sbjct: 48 LGEGSYGSVYKAVHKESSSIVAIKLVPVESDLHEII----KEISIMQQCDSPY--------VVRYYGSYFKQYDLWICMEYCGAGSVSDIMRLRKKTLTEDEIATILSDTLQGLVYLHLRRKIHRDIKAANILLNTEGYAKLADFGVAGQLTDTMAKRN-----------------TVIGTPFWMAPEVIEEIGYDCVADIWSLGITALEMAEGKPPYGEIHPMRAIFMIPQKPPPSFRE---PDRWSTEFIDFVSKCLVKEPDDRATATELLEHEF 292
BLAST of Protein kinase vs. Ensembl Fly
Match: GckIII (gene:FBgn0266465 transcript:FBtr0083399) HSP 1 Score: 113.62 bits (283), Expect = 1.966e-26 Identity = 81/282 (28.72%), Postives = 140/282 (49.65%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F++ + I +G +G++ K + ++ AIK I+ + D I+++++E +++ + Y +TKYYG+ +KG K++I M++ GGS +L+ + + +++L+GL +LH R +H D+K+ N+LL + + KL D G + + N S+++ + GT MAPE+I+ YD KADIWS T E+ G+P + VL + K P K D +++ K+P RPTAK LLK F
Sbjct: 13 FTKQERIGKGSFGEVFKGIDNRTQQVVAIKIIDLE-EAEDEIDDIQQEIMVLSQCDSPY--------VTKYYGSFLKGTKLWIIMEYLGGGSALDLMKA--GSFEEMHIGIILREVLKGLDYLHSERKLHRDIKAANVLLSEQGDVKLADFGVAGQL--TNTTSKRN--------------TFVGTPFWMAPEVIKQSQYDAKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPQLTGSYTKSFKD-----FVEACLNKDPENRPTAKELLKYPF 262
BLAST of Protein kinase vs. Ensembl Fly
Match: mbt (gene:FBgn0025743 transcript:FBtr0074285) HSP 1 Score: 105.145 bits (261), Expect = 1.386e-23 Identity = 72/278 (25.90%), Postives = 132/278 (47.48%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLG-CSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYK-KHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
I G G + R A+KK+ D+ + ++E L E+ I + + H I + Y + + ++++ M++ GG++ +++ + +E++ KQ L+ L++LH +IH D+KS +ILL + KL+D G C++ + L K +S GT M+PE+I L Y + DIWS + EM DG+P F + + ++ + P+ K H++ ++ S +D M +++P +R TA LL F
Sbjct: 374 IGEGSTGTVCIATDKSTGRQVAVKKM-------DLRKQQRRELLFNEVVIMR---DYHHPNIVETYSSFLVNDELWVVMEYLEGGALTDIVTH--SRMDEEQIATVCKQCLKALAYLHSQGVIHRDIKSDSILLAADGRVKLSDFGFCAQVSQELPKR-----------------KSLVGTPYWMSPEVISRLPYGPEVDIWSLGIMVIEMVDGEPPFFNEPPLQAMRRIRDMQPPNLKNAHKVSP----RLQSFLDRMLVRDPAQRATAAELLAHPF 618
BLAST of Protein kinase vs. Ensembl Fly
Match: Slik (gene:FBgn0035001 transcript:FBtr0072363) HSP 1 Score: 103.99 bits (258), Expect = 5.975e-23 Identity = 85/283 (30.04%), Postives = 135/283 (47.70%), Query Frame = 1
Query: 676 GRYGKISKIFQSGGSRIFAIK--KINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYS-QKHSKAGIQMKHKELPQSKFGTANNMAPEMI-----QGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHR--IKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G +GK+ K R A K ++ + NL+D MVEI+I SE+ H I + Y A K+++ +++ GG++ ++ L + L + ++ K + EGL+FLH N++IH DLK+ N+LL E KL D G S + NK++ QKH + GT MAPE++ + YD K DIWS T+ E+ +P + VL+K+ K E P ++ KE D + +K+P RPT +L++ F
Sbjct: 46 GAFGKVYKAQHKEQKRFAAAKMCQLEDEENLSD---------HMVEIDI---LSEIKHPNIVELYEAFSIDDKLWMLIEYCDGGALDSIMVELEKPLTEPQIAYVCKHMTEGLTFLHRNKVIHRDLKAGNVLLTMEGGVKLADFGVS----AKNKHTMQKHD-------------TFIGTPYWMAPELVLCETFRDNPYDHKVDIWSLGITLIELAQMEPPNSEMSPMRVLLKIQKSEPPKLEQPSRWSKEFND-----FLKKSLVKDPQVRPTTDVLMQHAF 294
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 128.642 bits (322), Expect = 2.896e-31 Identity = 90/282 (31.91%), Postives = 144/282 (51.06%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + + R A+K++ + + + + + AL EI + K L HERI +YYG + ++ + IFM++ GGSI + L + L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G SR ++++ S GI +S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A P H + C+ + +F+ E +RP A+ LL+ F
Sbjct: 365 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVS--ALECEIQLLK---NLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSY-GALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICL-----SGTGI--------KSVTGTPYWMSPEVISGEGYGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLPPH---VSDHCR--DFLKRIFV-ETKQRPAAEDLLRHTF 621
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 128.642 bits (322), Expect = 2.965e-31 Identity = 90/282 (31.91%), Postives = 144/282 (51.06%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + + R A+K++ + + + + + AL EI + K L HERI +YYG + ++ + IFM++ GGSI + L + L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G SR ++++ S GI +S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A P H + C+ + +F+ E +RP A+ LL+ F
Sbjct: 357 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVS--ALECEIQLLK---NLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSY-GALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICL-----SGTGI--------KSVTGTPYWMSPEVISGEGYGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLPPH---VSDHCR--DFLKRIFV-ETKQRPAAEDLLRHTF 613
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 122.865 bits (307), Expect = 4.301e-31 Identity = 85/284 (29.93%), Postives = 146/284 (51.41%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + +G YG + S G ++ A+K++ + +++ E + + L E+++ K L H I + G + + IFM++ GGSI +L LP++ + Y++QILEG+++LH NR+IH DLK NI+L KL D GC+R + L + SK +L +S GT MAPE+I + K+DIWS T++EM G+P A + L + +G +P +TD K + + ++ +RP+A+ LL+ F
Sbjct: 21 WTKGEVLGKGAYGTVYCGLTSQG-QLIAVKQVALDASTSEIAEK-EYDRLEREVDLLK---NLKHTNIVGFLGTALSENIVSIFMEYIPGGSISNILGQFGP-LPEKVFVLYSQQILEGVAYLHANRVIHRDLKGNNIMLMPTGVVKLIDFGCARRLSCLQ--TSTGSKG-------DLLKSVHGTPYWMAPEVINETGHGRKSDIWSIGCTVFEMATGKPPLAHMNKMAALYYIGARRGLMPSLSD---DFSTDAK--DFVQACLTRDQRQRPSAEELLRHPF 284
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: map3k22 (mitogen-activated protein kinase kinase kinase 22 [Source:ZFIN;Acc:ZDB-GENE-070928-11]) HSP 1 Score: 127.872 bits (320), Expect = 4.602e-31 Identity = 91/284 (32.04%), Postives = 140/284 (49.30%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGY--KMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ +G+ + RG +G + + R A K++ + + + + AL EI + K L HERI +YYG + K+ IF++F GGSI + L L ++ +YT+QIL+G+ +LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI +S GT M+PE+I G Y KADIWS A T+ EM +P +A + + K+A K + E + +F++E RPTA+ LL F
Sbjct: 360 WRQGKLLGRGAFGVVYLCYDVDTGRELAAKQVPFDPECQETSKEVN--ALECEIQLLK---NLHHERIVQYYGCLRDPVQKKLSIFVEFMPGGSIKDQLKAY-GALTEKVTRRYTRQILQGVHYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRIQTIC-----MSGTGI--------KSVTGTPYWMSPEVINGEGYGRKADIWSVACTVVEMLTQKPPWAEYEAMAAIFKIAT----QPTKPNLPEGVSDACRDFLRQIFVEE-KWRPTAEGLLSHPF 619
BLAST of Protein kinase vs. Ensembl Zebrafish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:ZFIN;Acc:ZDB-GENE-070910-1]) HSP 1 Score: 125.176 bits (313), Expect = 3.770e-30 Identity = 89/285 (31.23%), Postives = 143/285 (50.18%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + R A K++++ + + + AL EI + K L HERI +YYG + + + IFM++ GGS+ + L L + KYT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ S G+ +S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A P H I E+T + +F+ E RP+A+ LL+ F
Sbjct: 344 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVHFDPASPETSKEVS--ALECEIQLLK---NLHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAY-GALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM-----SSTGV--------RSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPSH-ISEHTR----DFLRCIFV-EAKYRPSAEELLRHPF 603
BLAST of Protein kinase vs. Ensembl Xenopus
Match: dennd1a (DENN domain containing 1A [Source:Xenbase;Acc:XB-GENE-5729862]) HSP 1 Score: 133.265 bits (334), Expect = 1.201e-32 Identity = 89/281 (31.67%), Postives = 143/281 (50.89%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + RG +G++ + R A+K++ + + + + + AL EI + K HERI +YYG + K+ IF+++ GGSI + L L + +YT+QIL+G+S+LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI +S GT M+PE+I G Y KAD+WS A T+ EM +P ++ + + K+A K R+ + M +F++E +RPTA+ LL+ F
Sbjct: 364 GKLLGRGAFGEVYLCYDVDKGRELAVKQVPFDPDSQETSKEVN--ALECEIQLLKLHR---HERIVQYYGCLRDPTERKLSIFVEYMPGGSIKDQLKAY-GALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANILRDSAGNVKLGDFGASKRIQTIC-----MSGTGI--------KSVTGTPYWMSPEVISGEGYGRKADVWSVACTVVEMLTEKPPWSEYEAMAAIFKIATQPT----KPRLPDTVSDACRDFMKQIFVEE-KRRPTAEELLRHLF 620
BLAST of Protein kinase vs. Ensembl Xenopus
Match: dennd1a (DENN domain containing 1A [Source:Xenbase;Acc:XB-GENE-5729862]) HSP 1 Score: 132.88 bits (333), Expect = 1.315e-32 Identity = 89/281 (31.67%), Postives = 143/281 (50.89%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + RG +G++ + R A+K++ + + + + + AL EI + K HERI +YYG + K+ IF+++ GGSI + L L + +YT+QIL+G+S+LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI +S GT M+PE+I G Y KAD+WS A T+ EM +P ++ + + K+A K R+ + M +F++E +RPTA+ LL+ F
Sbjct: 357 GKLLGRGAFGEVYLCYDVDKGRELAVKQVPFDPDSQETSKEVN--ALECEIQLLKLHR---HERIVQYYGCLRDPTERKLSIFVEYMPGGSIKDQLKAY-GALTENVTRRYTRQILQGVSYLHGNMIVHRDIKGANILRDSAGNVKLGDFGASKRIQTIC-----MSGTGI--------KSVTGTPYWMSPEVISGEGYGRKADVWSVACTVVEMLTEKPPWSEYEAMAAIFKIATQPT----KPRLPDTVSDACRDFMKQIFVEE-KRRPTAEELLRHLF 613
BLAST of Protein kinase vs. Ensembl Xenopus
Match: MAP3K2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:100493570]) HSP 1 Score: 127.102 bits (318), Expect = 1.032e-30 Identity = 92/283 (32.51%), Postives = 146/283 (51.59%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKK-EALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + + R A+K++ + D +E K+ AL EI + K L+HERI +YYG + + + IFM++ GGSI + L L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G S+ ++++ +G MK S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A P H + E+ C+ + +F+ E RP+++ LL+ F
Sbjct: 342 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDP---DSLETSKEVNALECEIQLLK---NLLHERIVQYYGCLRDSQEKTLSIFMEYMPGGSIKDQLKAY-GALTEFVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTI-------CLSGTGMK------SVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPAH-VSEH--CR--DFLKRIFV-EAKVRPSSEELLRHTF 598
BLAST of Protein kinase vs. Ensembl Xenopus
Match: MAP3K2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:100493570]) HSP 1 Score: 126.716 bits (317), Expect = 1.668e-30 Identity = 92/283 (32.51%), Postives = 146/283 (51.59%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKK-EALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + + R A+K++ + D +E K+ AL EI + K L+HERI +YYG + + + IFM++ GGSI + L L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G S+ ++++ +G MK S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A P H + E+ C+ + +F+ E RP+++ LL+ F
Sbjct: 370 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDP---DSLETSKEVNALECEIQLLK---NLLHERIVQYYGCLRDSQEKTLSIFMEYMPGGSIKDQLKAY-GALTEFVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRLQTI-------CLSGTGMK------SVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPQLPAH-VSEH--CR--DFLKRIFV-EAKVRPSSEELLRHTF 626
BLAST of Protein kinase vs. Ensembl Xenopus
Match: samd8 (sterile alpha motif domain containing 8 [Source:Xenbase;Acc:XB-GENE-1012742]) HSP 1 Score: 125.561 bits (314), Expect = 4.361e-30 Identity = 87/284 (30.63%), Postives = 145/284 (51.06%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAII-KGYK-MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + R A K++ + + + + + AL EI + K L H+RI +YYG++ KG K + IFM++ GGS+ + L L + +YT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ S GI +S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A ++ NT + + + + E +RPTA+ L++ F
Sbjct: 347 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQFDPDSPETSKEVS--ALECEIQLLK---NLHHDRIVQYYGSLRDKGEKTLTIFMEYMPGGSVKDQLKAY-GALTENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTIC-----MSGTGI--------RSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIAT----QPTNPQLPPNTSEQCRDFVKRILV-EARQRPTAEELIRHPF 606
BLAST of Protein kinase vs. Ensembl Mouse
Match: Map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:MGI Symbol;Acc:MGI:1203481]) HSP 1 Score: 125.946 bits (315), Expect = 1.082e-30 Identity = 84/284 (29.58%), Postives = 143/284 (50.35%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + RG YG + S G ++ A+K++ T+ E ++ L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYT+QIL+G+++LH+N ++H D+K N++L KL D GC++ + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P + D + L ++ ++RP+A LLK F
Sbjct: 248 WTKGEILGRGAYGTVYCGLTSLG-QLIAVKQVALDTSDKLATEKEYRK-LQEEVDLLKA---LKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAK----------RLAWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPARFSEPAADFVRLCL-----TRDQHERPSALQLLKHSF 510
BLAST of Protein kinase vs. Ensembl Mouse
Match: Map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:MGI Symbol;Acc:MGI:1346874]) HSP 1 Score: 126.331 bits (316), Expect = 1.868e-30 Identity = 88/285 (30.88%), Postives = 142/285 (49.82%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + R A K++ + + + + + AL EI + K L HERI +YYG + + + IFM++ GGS+ + L L + KYT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ S GI +S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A P H + D + +F+ E +RP+A+ LL +F
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVS--ALECEIQLLK---NLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAY-GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM-----SGTGI--------RSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRD-----FLRRIFV-EARQRPSAEELLTHHF 621
BLAST of Protein kinase vs. Ensembl Mouse
Match: Map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:MGI Symbol;Acc:MGI:1346873]) HSP 1 Score: 125.561 bits (314), Expect = 3.131e-30 Identity = 90/282 (31.91%), Postives = 140/282 (49.65%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + R A+K++ + + + + AL EI + K L+HERI +YYG + + + IFM++ GGSI + L L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G S+ ++++ +G MK S GT M+PE+I G Y KADIWS A T+ EM +P +A + + K+A P H D + +F+ E RP+A+ LL+ F
Sbjct: 359 GKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVN--ALECEIQLLK---NLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAY-GALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTI-------CLSGTGMK------SVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRD-----FLKRIFV-EAKLRPSAEELLRHMF 615
BLAST of Protein kinase vs. Ensembl Mouse
Match: Map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:MGI Symbol;Acc:MGI:1203481]) HSP 1 Score: 124.405 bits (311), Expect = 1.728e-29 Identity = 113/410 (27.56%), Postives = 187/410 (45.61%), Query Frame = 1
Query: 298 GYLPLHIASQGSNHEVLKFLLGQNCNIES------KDSNGWRPIHFAVLNKNMNNIKLLFGFGCE---LSMNDEILQDLINRPDYQDVKNIITTAIKNYQVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G + I G N E+ LLG C +E KD+N + + KN+N + G E D LQ IN D +N +T+ K K ++ H+ + +++G+ + RG YG + S G ++ A+K++ T+ E ++ L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYT+QIL+G+++LH+N ++H D+K N++L KL D GC++ + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P + D + L ++ ++RP+A LLK F
Sbjct: 1138 GKISQEILDPGKNEELTDELLG--CLVEELLALDEKDNNSCQIMTNEADAKNLNLVFSRRGNTIEELGRETTDVKLQRCINGFRIYDEENFLTSNEKKTLSDKSLN--------HEEAIF------WTKGEILGRGAYGTVYCGLTSLG-QLIAVKQVALDTSDKLATEKEYRK-LQEEVDLLKA---LKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRL----------AWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPARFSEPAADFVRLCL-----TRDQHERPSALQLLKHSF 1510
BLAST of Protein kinase vs. Ensembl Mouse
Match: Map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:MGI Symbol;Acc:MGI:1203481]) HSP 1 Score: 123.635 bits (309), Expect = 2.799e-29 Identity = 113/410 (27.56%), Postives = 187/410 (45.61%), Query Frame = 1
Query: 298 GYLPLHIASQGSNHEVLKFLLGQNCNIES------KDSNGWRPIHFAVLNKNMNNIKLLFGFGCE---LSMNDEILQDLINRPDYQDVKNIITTAIKNYQVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G + I G N E+ LLG C +E KD+N + + KN+N + G E D LQ IN D +N +T+ K K ++ H+ + +++G+ + RG YG + S G ++ A+K++ T+ E ++ L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYT+QIL+G+++LH+N ++H D+K N++L KL D GC++ + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P + D + L ++ ++RP+A LLK F
Sbjct: 934 GKISQEILDPGKNEELTDELLG--CLVEELLALDEKDNNSCQIMTNEADAKNLNLVFSRRGNTIEELGRETTDVKLQRCINGFRIYDEENFLTSNEKKTLSDKSLN--------HEEAIF------WTKGEILGRGAYGTVYCGLTSLG-QLIAVKQVALDTSDKLATEKEYRK-LQEEVDLLKA---LKHVNIVAYLGTCLEENTLSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTRQILQGVAYLHDNCVVHRDIKGNNVMLMPTGIIKLIDFGCAKRL----------AWAGLNGTHSDMLKSMRGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPARFSEPAADFVRLCL-----TRDQHERPSALQLLKHSF 1306
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q54R82|MKKA_DICDI (Mitogen-activated protein kinase kinase kinase A OS=Dictyostelium discoideum OX=44689 GN=mkkA PE=1 SV=2) HSP 1 Score: 134.806 bits (338), Expect = 3.512e-32 Identity = 98/295 (33.22%), Postives = 146/295 (49.49%), Query Frame = 1
Query: 646 EFSEGQFIDRGRYGKISKIFQSGGSRIFAIKK-----INWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLK-YTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMK--LAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYFDINI 1506
++ +GQ + RG YG + +FA+K+ IN L ++I + KE I RS L H+ I +Y G + + +F+++ GGSI LL G E ++K YTKQIL+GLSFLH N IIH D+K NIL+DT+ KL+D GCS+ S +GI + K + GT MAPE+I+ + +DIWS I EM QP ++ E +M + +P+ H +E D ++ F ++P +RP A LLK F +N+
Sbjct: 169 KWQKGQILGRGGYGSVYLGLNKDTGELFAVKQLEIVDINSDPKLKNMILSFSKE-------IEVMRS-LRHDNIVRYLGTSLDQSFLSVFLEYIPGGSISSLLGKF--GAFSENVIKVYTKQILQGLSFLHANSIIHRDIKGANILIDTKGIVKLSDFGCSK------------SFSGIVSQFKSMQ----GTPYWMAPEVIKQTGHGRSSDIWSLGCVIVEMATAQPPWSNITELAAVMYHIASSNSIPNIPSHMSQEAFD-----FLNLCFKRDPKERPDANQLLKHPFIMNL 432
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q56UN5|M3K19_HUMAN (Mitogen-activated protein kinase kinase kinase 19 OS=Homo sapiens OX=9606 GN=MAP3K19 PE=2 SV=1) HSP 1 Score: 131.339 bits (329), Expect = 5.834e-31 Identity = 86/284 (30.28%), Postives = 143/284 (50.35%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + +G YG + S G ++ A+K++ T+ N + + L E+++ K L H I Y G ++ + IFM+F GGSI ++N LP+ KYTKQIL+G+++LHEN ++H D+K N++L KL D GC+R + + AG+ H ++ +S GT MAPE+I Y K+DIWS T++EM G+P A + + +G +P H + D + ++ ++RP+A LLK F
Sbjct: 1061 WTKGEILGKGAYGTVYCGLTSQG-QLIAVKQVALDTS-NKLAAEKEYRKLQEEVDLLKA---LKHVNIVAYLGTCLQENTVSIFMEFVPGGSISSIINRF-GPLPEMVFCKYTKQILQGVAYLHENCVVHRDIKGNNVMLMPTGIIKLIDFGCARRL----------AWAGLNGTHSDMLKSMHGTPYWMAPEVINESGYGRKSDIWSIGCTVFEMATGKPPLASMDRMAAMFYIGAHRGLMPPLPDHFSENAAD-----FVRMCLTRDQHERPSALQLLKHSF 1323
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q99759|M3K3_HUMAN (Mitogen-activated protein kinase kinase kinase 3 OS=Homo sapiens OX=9606 GN=MAP3K3 PE=1 SV=2) HSP 1 Score: 126.331 bits (316), Expect = 1.126e-29 Identity = 87/285 (30.53%), Postives = 142/285 (49.82%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + R A K++ + + + + + AL EI + K L HERI +YYG + + + IFM++ GGS+ + L L + KYT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ +G M+ S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A P H + D + +F+ E +RP+A+ LL +F
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVS--ALECEIQLLK---NLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAY-GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTI-------CMSGTGMR------SVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRD-----FLRRIFV-EARQRPSAEELLTHHF 621
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q61084|M3K3_MOUSE (Mitogen-activated protein kinase kinase kinase 3 OS=Mus musculus OX=10090 GN=Map3k3 PE=1 SV=1) HSP 1 Score: 126.331 bits (316), Expect = 1.307e-29 Identity = 88/285 (30.88%), Postives = 142/285 (49.82%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + R A K++ + + + + + AL EI + K L HERI +YYG + + + IFM++ GGS+ + L L + KYT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ S GI +S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A P H + D + +F+ E +RP+A+ LL +F
Sbjct: 362 WRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVS--ALECEIQLLK---NLQHERIVQYYGCLRDRAEKILTIFMEYMPGGSVKDQLKAY-GALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM-----SGTGI--------RSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSHISEHGRD-----FLRRIFV-EARQRPSAEELLTHHF 621
BLAST of Protein kinase vs. UniProt/SwissProt
Match: sp|Q9Y2U5|M3K2_HUMAN (Mitogen-activated protein kinase kinase kinase 2 OS=Homo sapiens OX=9606 GN=MAP3K2 PE=1 SV=2) HSP 1 Score: 125.946 bits (315), Expect = 1.784e-29 Identity = 90/282 (31.91%), Postives = 140/282 (49.65%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + R A+K++ + + + + + AL EI + K L+HERI +YYG + + + IFM++ GGSI + L L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G S+ ++++ +G MK S GT M+PE+I G Y KADIWS A T+ EM +P +A + + K+A P H D + +F+ E RP+A LL+ F
Sbjct: 359 GKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVN--ALECEIQLLK---NLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAY-GALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTI-------CLSGTGMK------SVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRD-----FLKRIFV-EAKLRPSADELLRHMF 615
BLAST of Protein kinase vs. TrEMBL
Match: A0A0H3YJG2 (Slc42a-1 OS=Schmidtea mediterranea OX=79327 GN=slc42a-1 PE=2 SV=1) HSP 1 Score: 180.644 bits (457), Expect = 4.513e-45 Identity = 146/479 (30.48%), Postives = 226/479 (47.18%), Query Frame = 1
Query: 190 LDSKRYSAF------IESLKYGDLPTVEQEFQPIFLN-QPDSSGYLPLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDEILQ----------------------------DLINRPDYQ-----DVKNIITTAIKNYQV----GKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDER----LLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLL 1482
L+ +RYS F I+++K G + V++ + L + S P+ A + + +++K+ + Q CN++S D R +H+AV++ N + +KLL G +++ D +L D + R Q D +N+I IK Q+ EM LKC C+HKFC TS + + I G YG + +SG R FA+KKI K N+ A +E NIN +++ L HERI K++GA K YIFM++ L+TL + ++ LL + KQILE LSFLHE IIH D+K +N+LLD + N KL+D G S + S+ + QK + GT APE++ Y DIWS AT+ ++ GQP + + ++ ++ +YK + E I +L+D M K+ KR +AK LL
Sbjct: 496 LEYERYSEFEKFGQLIKAIKDGSIEDVKKYYSRRILEIKLGSYSRSPILYACKYGHRKIVKYFIKQKCNVDSFDCEFRRALHYAVISNNNDIVKLLIESGAAINVPDSLLMMPIHLACKVNNIEAAQLLMENNCDMVTLDKLKRSPLQIAETGDFENMIKL-IKECQIIREIAAEMQLKCGKLCNHKFCYTSFQRKKIKNRKCIASGSYGTVFLYNESGTDRKFAVKKIP-KQNI---------RARYIEANINDFKNLLCHERIVKHFGAFHKKENHYIFMEY---------LDTLQKKKYQKKSPGDLLLFAKQILEALSFLHERSIIHRDIKPENVLLDIDGNLKLSDFGLSLLLSSVAEDIQKEGRCC-------------GTYCYAAPEILNAELYTCSVDIWSLGATMIQLCTGQPPYHNLGDGAIITVISTTREIEYK---LPEYMPKYISNLIDHMLEKDQYKRLSAKKLL 938
BLAST of Protein kinase vs. TrEMBL
Match: D2VYH3 (Predicted protein OS=Naegleria gruberi OX=5762 GN=NAEGRDRAFT_53261 PE=4 SV=1) HSP 1 Score: 148.288 bits (373), Expect = 3.879e-34 Identity = 100/280 (35.71%), Postives = 145/280 (51.79%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFA--GKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLL 1482
+ +G FI G GK+ + + FAIK+ + + D++E LK E+L EIN+ K EL HE I +YYGA + G + IF+++ GGS+ LL L ++ + YT QIL+GL +LHENRI+H D+K NIL+ E KL D G SR I+ + S + +S GT + MAPE+I + ADIWS T+ EM+ G+P F V+ A E+P + + + E CK + FI++PN R T LL
Sbjct: 399 YKKGDFIGSGASGKVFLGYNLDDGKFFAIKECTFDSVPEDILE-LKLESLQREINLMK---ELCHENIVQYYGAEVTGTTLNIFLEYVPGGSVSSLLRRYGR-LSEDVVRHYTTQILKGLKYLHENRIVHRDIKGANILVSVEGAIKLADFGASRKIQDIMTLSTEF-------------KSLLGTPHFMAPEVIMQTGHGRSADIWSIGCTVVEMYTGKPPFTEFTTAAAVMFHIAASTEMPSFPEF-VSEG--CK--KFLYKCFIRDPNLRATVDDLL 655
BLAST of Protein kinase vs. TrEMBL
Match: A0A5B8MXT0 (Mitogen-activated protein kinase OS=Chloropicon primus OX=1764295 GN=A3770_17p78750 PE=4 SV=1) HSP 1 Score: 145.976 bits (367), Expect = 9.907e-34 Identity = 123/408 (30.15%), Postives = 187/408 (45.83%), Query Frame = 1
Query: 289 DSSGYLPLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDEILQDLINRPDYQDVKNIITTAIKNYQVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKG--YKMYIFMDFYHGGSIYELLNTLPEGLPDERLLK-YTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQ-PLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
D + PLH A + + +L Q +I ++ G P+ A + + ++ LF +E + RP +D ++ + K + G EM E+ +G+ + G YG++ +I A+K+I + + +NLK AL EI K L HE I +YYGA + + MY+F+++ GGSI +L G E L K YTKQIL GL FLHEN+ IH D+K NIL+ E + KL D G S R++ + N S +G+ +S G+ MAPE+++G + KADIWS T+ EM G+ P + ++AK E P K+ K+ + + F +P KRPTA LL T F
Sbjct: 317 DQDAFTPLHHACAEGHARCAEVVLSQGASIRARTKGGLTPLQLA----STDGVRDLFNPSSRSRKAEEEDGGVPERPRGRDSNSMFRESSKRIESG-EM--------------------EWKKGELLGEGAYGRVYAGLNHETGQIMAVKQIAVDMDNDKHTDNLK--ALEREIEFYK---TLKHEHIVEYYGAFLDKDQHLMYVFLEYVSGGSISSMLKRF--GPFSEALTKIYTKQILRGLLFLHENKTIHRDVKGANILITQEGSAKLADFGASKRYVNAEN------SGSGLSNS-----KSITGSVYWMAPEVMKGTGHGRKADIWSLGCTVVEMLTGKHPWKEYDNTWTAMFQIAKSESGPGLPKNISKDARE-----FLQLCFQLDPTKRPTALDLLGTQF 676
BLAST of Protein kinase vs. TrEMBL
Match: T1G1N2 (Protein kinase domain-containing protein OS=Helobdella robusta OX=6412 GN=20214980 PE=4 SV=1) HSP 1 Score: 138.272 bits (347), Expect = 2.070e-33 Identity = 90/285 (31.58%), Postives = 145/285 (50.88%), Query Frame = 1
Query: 640 FNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
FN + +G+ + G +G++ + A+K++N D+ + ++ AL EI K +L + RI +YYG+ + + + IFM+F GGS+ + + L + +YTKQ+LEGL FLH I+H D+K NIL D E N KLTD G ++ + S+ + SK K + GT M+PE+I+G Y K DIWS T+ EM G P + + + K+A P YK + +T ++ + F ++P +RP+AK+L F
Sbjct: 3 FN-WKKGKILGAGGFGQVYLCYDVDTGVELAVKQVNVYCQSEDISKEVR--ALQSEI---KLLQDLSNPRIVQYYGSQKEPHMLSIFMEFVPGGSVKDQIQDYGP-LTESVTKRYTKQVLEGLEFLHSLMIVHRDIKGANILRDHEGNIKLTDFGAAKRLSSIVNKTADVSKNLTGAK------TMTGTPYYMSPEIIEGKRYGRKVDIWSLGCTVVEMLTGHPPWHEYEGVAAIFKIATQPHPSYK---LPPDTSLQVKDFLSCCFERDPERRPSAKILYNHMF 271
BLAST of Protein kinase vs. TrEMBL
Match: A0A210PFZ5 (Mitogen-activated protein kinase kinase kinase 2 OS=Mizuhopecten yessoensis OX=6573 GN=KP79_PYT24565 PE=4 SV=1) HSP 1 Score: 139.043 bits (349), Expect = 9.946e-33 Identity = 94/310 (30.32%), Postives = 154/310 (49.68%), Query Frame = 1
Query: 574 GKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELL---NTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G ++D + D F + + + +G + G +G++ + R A+K++N LN + KE +E I R+ HERI Y+G + IFM++ GGSI + L L EG+ KYT+Q+LEGL+FLH+N I+H D+K+ N+L D + N KL D G S+ + ++ S G +S GT + MAPE+I G Y KAD+WS T+ EM G+P ++ + + K+A E P+++ + + + L F + P +RP+++ LL+ F
Sbjct: 105 GNDLDSPIHNYSDLTFSKSPRAPSNWKKGHRLGSGSFGEVFVCYDKDSGRELAVKQVN----LNQMNAETSKEVRALENEIQLLRN-FQHERIVSYFGCHQDHSILSIFMEYMPGGSIKDELAKYGPLTEGV----TRKYTRQMLEGLAFLHKNVIVHRDIKAANVLRDLQGNIKLADFGASKRLHTIC------SATGF--------KSFVGTPHYMAPEVINGEGYGRKADVWSLGCTVVEMISGKPPWSELESMAAIYKIATAERPEFELPQRSSEFSREFLRL---TFRRNPLERPSSEDLLRHRF 388
BLAST of Protein kinase vs. Ensembl Cavefish
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 125.176 bits (313), Expect = 3.694e-32 Identity = 87/284 (30.63%), Postives = 147/284 (51.76%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFA--GKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+++G+ + RG YG + S G ++ A+K++ + ++ E KE +E ++ ++ L H I + G + + IFM++ GGSI +LN LP++ YT+Q+LEG+++LHENR+IH DLK N++L KL D GC+R + L HS + +L +S GT MAPE+I + K+D+WS T++EM G+P A GK + + KG +P + ++ + S + + I + +RP+A LL+ F
Sbjct: 16 WAKGEVLGRGAYGTVYCGLTSQG-QLIAVKQVLLDVSTSETAE---KEYSRLEREVDLLKN-LEHPNIVGFLGTALTDNVISIFMEYVPGGSISSVLNRFGP-LPEKVFALYTRQVLEGVAYLHENRVIHRDLKGNNLMLMPTGVVKLIDFGCARRLNRLT-----HSGG-----NSDLLKSVHGTPYWMAPEVINETGHGKKSDVWSIGCTVFEMATGKPPLAHMGKMAALFYIGARKGLMPP-----LPDDFSEEAKSFVKACLINQ-KQRPSAADLLRHPF 277
BLAST of Protein kinase vs. Ensembl Cavefish
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3-like [Source:NCBI gene;Acc:103044968]) HSP 1 Score: 130.568 bits (327), Expect = 5.030e-32 Identity = 89/284 (31.34%), Postives = 145/284 (51.06%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ +G+ + RG +G++ + + R A+K++ + ++ + + AL EI + K L HERI +YYG + + K+ IF++F GGSI + L L ++ +YT+QIL+G+ +LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI ++ GT M+PE+I G Y KAD+WS A T+ EM +P +A + + K+A K + E + +F++E RPTA+ LL F
Sbjct: 357 WRQGKLLGRGAFGEVYLCYDADTGRELAVKQVPFDPECHETSKEVN--ALECEIQLLK---NLRHERIVQYYGCLRDPEQRKLSIFVEFMPGGSIKDQLKAY-GALTEKVTRRYTRQILQGVFYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRIQTIC-----MSGTGI--------KTVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAEYEAMAAIFKIAT----QPTKPNLPEGVSDACRDFLRQVFVEE-KWRPTAEGLLSHPF 616
BLAST of Protein kinase vs. Ensembl Cavefish
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3-like [Source:NCBI gene;Acc:103044968]) HSP 1 Score: 130.183 bits (326), Expect = 6.375e-32 Identity = 89/284 (31.34%), Postives = 145/284 (51.06%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ +G+ + RG +G++ + + R A+K++ + ++ + + AL EI + K L HERI +YYG + + K+ IF++F GGSI + L L ++ +YT+QIL+G+ +LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI ++ GT M+PE+I G Y KAD+WS A T+ EM +P +A + + K+A K + E + +F++E RPTA+ LL F
Sbjct: 354 WRQGKLLGRGAFGEVYLCYDADTGRELAVKQVPFDPECHETSKEVN--ALECEIQLLK---NLRHERIVQYYGCLRDPEQRKLSIFVEFMPGGSIKDQLKAY-GALTEKVTRRYTRQILQGVFYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRIQTIC-----MSGTGI--------KTVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAEYEAMAAIFKIAT----QPTKPNLPEGVSDACRDFLRQVFVEE-KWRPTAEGLLSHPF 613
BLAST of Protein kinase vs. Ensembl Cavefish
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:103026704]) HSP 1 Score: 128.642 bits (322), Expect = 2.654e-31 Identity = 90/282 (31.91%), Postives = 142/282 (50.35%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + + R A+K++ + + + + + AL EI + K L HERI +YYG + ++ + IFM++ GGSI + L + L + KYT+QILEG+ +LH N I+H D+K NIL D+ N KL D G SR ++++ S GI +S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A P H D + +F+ E +RP A+ LL+ F
Sbjct: 362 GKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVS--ALECEIQLLK---NLFHERIVQYYGCLRDTHERTLSIFMEYMPGGSIKDQLKSY-GALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICL-----SGTGI--------KSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTLRPPWAEFEAMAAIFKIATQPTNPALPAHVSDHCRD-----FLKRIFV-ETKQRPAAEELLRHIF 618
BLAST of Protein kinase vs. Ensembl Cavefish
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:103034596]) HSP 1 Score: 123.25 bits (308), Expect = 1.585e-29 Identity = 86/285 (30.18%), Postives = 140/285 (49.12%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + R A K++ + + KE +E I ++ L HERI +YYG + + + IFM++ GGS+ + L L + KYT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ S G+ +S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A P H ++ D + +F+ E RP+A+ LL+ F
Sbjct: 356 WRRGKLLGQGAFGRVYLCYDVDTGRELAAKQVQF----DPASPETSKEVSTLECEIQLLKN-LHHERIVQYYGCLRDHNEKTLTIFMEYMPGGSVKDQLKAY-GALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM-----SSTGV--------RSVTGTPYWMSPEVISGDGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPILPSHTSEQTRD-----FIRRIFV-EAKHRPSAEELLRHPF 615
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:ZFIN;Acc:ZDB-GENE-120215-96]) HSP 1 Score: 127.872 bits (320), Expect = 9.266e-32 Identity = 91/285 (31.93%), Postives = 143/285 (50.18%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGEL-PDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G++ + + R A+K++ + + V + + AL EI + K L HERI +Y+G + + + IFM++ GGSI + L L + KYT+QILEG+SFLH N I+H D+K NIL D+ N KL D G S+ ++++ G M+ S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A P H + D L+ +F+ E RP+A+ LL+ F
Sbjct: 359 WQRGKLLGQGAFGRVYLCYDADTGRELAVKQVQF--DPGSVETSKEVNALECEIQLLK---NLQHERIVQYFGCLRDPQQKTLSIFMEYMPGGSIKDQLRAY-GALTENVTRKYTRQILEGVSFLHGNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTI-------CSQGTAMR------SVTGTPYWMSPEVINGEGYGRKADIWSVGCTVVEMLTEKPPWAEFEAMAAIFKIATQPTDPRLPLHASEHARD-----LLRRIFV-EAKLRPSAEDLLRHPF 618
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: map3k19 (mitogen-activated protein kinase kinase kinase 19 [Source:ZFIN;Acc:ZDB-GENE-081104-140]) HSP 1 Score: 108.612 bits (270), Expect = 6.722e-27 Identity = 68/225 (30.22%), Postives = 110/225 (48.89%), Query Frame = 1
Query: 829 SELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA--KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ L H + +Y G ++G + IFM+F GG++ E + L + Y Q+ GL++LH + ++HGD+K N ++ KL D GC+ R +L+ H G+ H GTA MAPE+I G Y +AD+WS T++EM G+P FA L+ + G +P + KE + ++ FI++ KRP+++ LL F
Sbjct: 76 TTLHHPNVVEYLGTEMEGNRFSIFMEFVPGGTVAETVRGFGP-LGESVCRSYIAQMTRGLAYLHGHGVMHGDVKGSNAVITPAGVVKLIDFGCAQRVALALSC----HENGGLHSVH--------GTAYWMAPEVINGTGYARRADVWSLGCTLHEMAVGRPPFADMAPMAALLHIGIRNGIMPGLPQAFSKEAQE-----FVEQCFIRDKLKRPSSQELLSHPF 282
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: stk25a (serine/threonine kinase 25a [Source:ZFIN;Acc:ZDB-GENE-041010-92]) HSP 1 Score: 109.383 bits (272), Expect = 3.465e-26 Identity = 86/302 (28.48%), Postives = 148/302 (49.01%), Query Frame = 1
Query: 607 CDHKFCLTSICFNE---FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLK--SQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKF-GTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
C H + C + F++ + I +G +G++ K + + AIK I+ + +++ + ++ ++ + + + Y +T Y+G+ +KG K++I M++ GGS +L+ P L + ++ ++IL+GL +LH R IH D+K + N+LL + + KL D G AG Q+ ++ ++ F GT MAPE+I+ +YD KADIWS T E+ G+P + VL + K P ++ N +DS K+P RPTAK LLK F
Sbjct: 9 CPHPRPPQNSCADPEELFTKQERIGKGSFGEVFKGIDNRTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD-SPY--------VTHYFGSYLKGTKLWIIMEYLGGGSALDLIKPGP--LEEHQIATILREILKGLDYLHSERKIHRDIKGPAANVLLSEQGDVKLADFGV----------------AG-QLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITAIELAKGEPPNSELHPMRVLFLIPKNNPPT-----LEGNYSKAFKEFVDSCLNKDPQFRPTAKELLKHKF 277
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007848.1 (pep scaffold:Pmarinus_7.0:GL476358:287782:303246:1 gene:ENSPMAG00000007083.1 transcript:ENSPMAT00000007848.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 107.457 bits (267), Expect = 4.139e-25 Identity = 79/280 (28.21%), Postives = 135/280 (48.21%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDN-CKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENV-------VLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLL 1482
+ RGR+G + S FA+K+++ ++ EN E++I S L R+ + YGA+ +G ++ +FM GG++ +++ + LP + + YT Q+LE L +LH+N ++HGD+K+ NIL+ + N L D G S+ + +K K Q GT +MAPE+ +D KAD+WSA + M +G+ + G+ V V + E P++ T C ++ ++ S K+ RPTA +LL
Sbjct: 40 LGRGRFGNVFVGRDLCTSFHFAVKQLS----VDKFSEN--------ELSI---WSRLDSLRLVQLYGAVREGPRLSLFMQVAEGGTLDVMISDNKQ-LPQDLAMHYTCQVLEALEYLHQNNVLHGDVKADNILMSADGNQVWLCDFGFSQLLPPGSKVLPKD-------------QQPRGTQTHMAPEVAASAGHDCKADVWSACCVLLHMLNGRHPWMGRFAGVKVLYFVIVQQEAPVSEAPEW-------CTSC-VLDVLRSGLQKDAAARPTASLLL 282
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007414.1 (pep scaffold:Pmarinus_7.0:GL476981:230882:244405:1 gene:ENSPMAG00000006689.1 transcript:ENSPMAT00000007414.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 95.1301 bits (235), Expect = 7.739e-22 Identity = 69/274 (25.18%), Postives = 124/274 (45.26%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGL-PDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLF-AGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLL 1482
I G +GK + ++ IK+IN + +KE ++ + + H I Y + + +YI MD+ GG +++ +N L ++++L + Q+ L +H+ +I+H D+KSQNI L +L D G +R + S EL ++ GT ++PE+ + Y+ K+D+W+ +YEM + F AG +N+VL K+ +G P H E + S + + ++P RP +LL
Sbjct: 10 IGEGSFGKAMLVKSKADGHLYVIKEINISRMSPKERDEARKEVCVL--------ANMRHPNIVSYKESFEERGNLYIVMDYCEGGDLFKRINAQKGVLFSEDQILDWLVQLCLALKHVHDRKILHRDIKSQNIFLTKAGIVQLGDFGIARVLNSTT----------------ELARTCIGTPYYLSPEICENKPYNHKSDMWALGCVLYEMCTLRHAFEAGNMKNLVL-KIIRGSFPPVSAHYSSE-----LRSTLSGLLRRDPRARPPVAVLL 253
BLAST of Protein kinase vs. Ensembl Yeast
Match: CDC15 (Protein kinase of the Mitotic Exit Network; localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p; required for spindle disassembly after meiosis II; relocalizes to the cytoplasm upon DNA replication stress [Source:SGD;Acc:S000000072]) HSP 1 Score: 112.849 bits (281), Expect = 7.712e-27 Identity = 82/277 (29.60%), Postives = 124/277 (44.77%), Query Frame = 1
Query: 661 QFIDRGRYGKISKIFQSGGSRIFAIKKINWKTN--LNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLK 1485
Q I RG YG + K ++ AIK++ ++ + LND+ M EI++ K L H I KY+G I K Y++YI +++ GS+ L++ GL + Y Q L GL +LH +IH D+K+ NILL ++ KL D G S + S + + + GT N MAPE++ +DIWS AT+ EM P + + + + Y E + + F+K KRPTA LLK
Sbjct: 29 QVIGRGSYGVVYKAINKHTDQVVAIKEVVYENDEELNDI---------MAEISLLK---NLNHNNIVKYHGFIRKSYELYILLEYCANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTVKLADFGVSTIVNS----------SALTLA---------GTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVENDTY--YPPSSFSE----PLKDFLSKCFVKNMYKRPTADQLLK 268
BLAST of Protein kinase vs. Ensembl Yeast
Match: STE11 (Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]) HSP 1 Score: 111.694 bits (278), Expect = 1.867e-26 Identity = 83/255 (32.55%), Postives = 129/255 (50.59%), Query Frame = 1
Query: 751 KTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLK-YTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLK-TYFDINIL 1509
KTN N I +AL E+N+ K EL HE I YYGA +G + IF+++ GGS+ +LN G +E L+ +T+QIL G+++LH+ IIH D+K NIL+D + K+TD G S+ + LNK K +A +Q G+ M+PE+++ + KADIWS + EMF G+ F + + K+ P+ E + + F + RP+A LL+ + D +I+
Sbjct: 488 KTNQN--IHRKMVDALQHEMNLLK---ELHHENIVTYYGASQEGGNLNIFLEYVPGGSVSSMLNNY--GPFEESLITNFTRQILIGVAYLHKKNIIHRDIKGANILIDIKGCVKITDFGISKKLSPLNKKQNK--RASLQ-----------GSVFWMSPEVVKQTATTAKADIWSTGCVVIEMFTGKHPFPDFSQMQAIFKIGTNTTPEIPSWATSEGKN-----FLRKAFELDYQYRPSALELLQHPWLDAHII 717
BLAST of Protein kinase vs. Ensembl Yeast
Match: SPS1 (Putative protein serine/threonine kinase; localizes to the nucleus and cytoplasm; required for efficient spore packaging, prospore membrane development and closure and localization of enzymes involved in spore wall synthesis; interacts with and required for Ssp1p phosphorylation and turnover; member of the GCKIII subfamily of STE20 kinases; multiply phosphorylated on S/T residues; interacts with 14-3-3 proteins, Bmh1p and Bmh2p; expressed at the end of meiosis [Source:SGD;Acc:S000002931]) HSP 1 Score: 106.686 bits (265), Expect = 2.880e-25 Identity = 88/283 (31.10%), Postives = 126/283 (44.52%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELL-NTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMI--QGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYFDINI 1506
I RG +G + K I AIK +N + + D IE L +E + +EL IT Y +++ M+I M++ GGS +LL + GLP+E++ ++ GL +LHE R IH D+K+ NILL+ E KL D G S I S K + GT MAPE++ + Y+ KADIWS T YE+ G P + V+ L K + P + D + +K P RP+A LL F NI
Sbjct: 24 IGRGNFGDVYKAVDRVTQEIVAIKVVNLEHSDED-IELLAQEIFFL--------AELKSPLITNYIATMLEDVSMWIVMEYCGGGSCSDLLKRSYVNGLPEEKVSFIIHEVTLGLKYLHEQRKIHRDIKAANILLNEEGMVKLGDFGVSGHIRSTLKR-----------------DTFVGTPYWMAPEVVCCEVDGYNEKADIWSLGITTYELLKGLPPLSKYDPMKVMTNLPKRKPPKLQGPFSDAAKD-----FVAGCLVKTPADRPSAYNLLSFEFVKNI 275
BLAST of Protein kinase vs. Ensembl Yeast
Match: BCK1 (MAPKKK acting in the protein kinase C signaling pathway; the kinase C signaling pathway controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p; MAPKKK is an acronym for mitogen-activated protein (MAP) kinase kinase kinase [Source:SGD;Acc:S000003631]) HSP 1 Score: 105.916 bits (263), Expect = 1.819e-24 Identity = 92/298 (30.87%), Postives = 147/298 (49.33%), Query Frame = 1
Query: 640 FNEFS--EGQFIDRGRYGKISKIFQSGGSRIFAIKKINWK--TNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKY-TKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMI---QGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIIS-----LMDSMFIKEPNKRPTAKMLLKTYF 1494
+ EF+ +G+ I +G +G + + A+K++ ++ N+ I + EAL E++ K +L H I +Y G K +F+++ GGS+ L+ G DE L+K+ T Q+L+GL++LH I+H D+K+ N+LLD + CK++D G SR K +S + + M+ GT MAPEM+ QG Y K DIWS + EMF G+ ++ + + K+ K + I E+T +IS +D+ F P KRPTA LL F
Sbjct: 1170 YKEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTV-EALRSEVSTLK---DLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMY--GRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISR------KSKDIYSNSDMTMR---------GTVFWMAPEMVDTKQG--YSAKVDIWSLGCIVLEMFAGKRPWSNLEVVAAMFKIGKSK----SAPPIPEDT-LPLISQIGRNFLDACFEINPEKRPTANELLSHPF 1439
BLAST of Protein kinase vs. Ensembl Yeast
Match: KIC1 (Protein kinase of the PAK/Ste20 family, required for cell integrity; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body; part of the RAM network that regulates cellular polarity and morphogenesis [Source:SGD;Acc:S000001144]) HSP 1 Score: 105.531 bits (262), Expect = 2.155e-24 Identity = 84/288 (29.17%), Postives = 144/288 (50.00%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKE----ALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYT-KQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMI-QGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
F + I RG++G + K + R++AIK +N ++ +D +E++++E A + +I+ IT+YYG+ +K ++I M+ GGS+ LL G DE+ + +++L L +H++ +IH D+K+ N+L+ E N KL D G + +N+ S + Q+ GT MAPE+I +G+ YD K DIWS T YE+ G P + E + M+L P + R + + I+L ++P +R +A LLK+ F
Sbjct: 23 FKRTEVIGRGKFGVVYKGYNVKTGRVYAIKVLNLDSD-SDEVEDVQREIQFLASLKQIS-----------NITRYYGSYLKDTSLWIIMEHCAGGSLRSLLR---PGKIDEKYIGVIMRELLVALKCIHKDNVIHRDIKAANVLITNEGNVKLCDFGVA---AQVNQTSLRR-------------QTMAGTPYWMAPEVIMEGVYYDTKVDIWSLGITTYEIATGNPPYC-DVEALRAMQLIIKSKPPRLEDRSYSTSLKEFIAL---CLDEDPKERLSADDLLKSKF 275
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO41410 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S4G7]) HSP 1 Score: 131.724 bits (330), Expect = 5.355e-35 Identity = 97/293 (33.11%), Postives = 140/293 (47.78%), Query Frame = 1
Query: 640 FNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLL-KYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLA----KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYFDIN 1503
N + +G+ + G +G++ R A+K+I LN +N K AL EI K +ERI +YYG +YIFM++ GGSI+E + G +E L KY++QILEG+ +LH NRI+H D+K NIL D N KL D G S+ ++++ SK G + H GT MAPE+I G Y KAD+WS T+ EM +P +A + L K+A + ELP + + + S RP+A LL+ F N
Sbjct: 1 MNNWRKGKLLGAGAFGQVYMCHDLDTGRELAVKQIE-TGQLNSSTKNEVK-ALEGEIEFMK---AFRNERIVQYYGIETDDLHIYIFMEYLPGGSIHEHIKQ--HGALNESLTRKYSRQILEGILYLHTNRIVHRDIKGANILRDLYGNVKLADFGASKRLQTI------RSKTGFRSVH--------GTPYWMAPEVINGEGYGRKADVWSVGCTVVEMLTTKPPWADFEPMAALFKIATQPTEPELPS--------DLSVDAVEFVRSTLRMNSKSRPSADELLRFSFVTN 264
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO47821 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RL88]) HSP 1 Score: 117.857 bits (294), Expect = 5.530e-30 Identity = 84/286 (29.37%), Postives = 137/286 (47.90%), Query Frame = 1
Query: 646 EFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGE-LPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
E+ +G + +G +G + + G I A+K++ N D E + E L E+ + K L H+ I +Y G + + + IFM+F GGSI + L + +YT+QIL+G+S+LH N +IH D+K NI+L KL D GC++ K G + + +S GT MAPE+I+ + K+DIWS T++EM GQP ++ + + G +P R+ E+ I + S ++ + RP+A LL+ F
Sbjct: 4 EWQKGNVLGKGAFGTVFLGLVNTGELI-AVKQVELHPNNVDAAER-QYEKLQEEVGLLK---SLKHKNIVQYIGTCMDDSQCTINIFMEFVPGGSIAQALKRF-GAFVEPVFRRYTRQILDGVSYLHNNNVIHRDIKGGNIMLMPNGVIKLIDFGCAK----------KICMVGAHVSKSNILRSMRGTPYWMAPEVIRETGHGRKSDIWSIGCTVFEMATGQPPWSNVPPLSAIFAIGNGSPVP-----RLDESFSAAAIDFVTSCMTRDQDTRPSADELLRHDF 268
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO35743 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SKK8]) HSP 1 Score: 109.383 bits (272), Expect = 1.513e-27 Identity = 72/218 (33.03%), Postives = 109/218 (50.00%), Query Frame = 1
Query: 841 HERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQ-ILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDC--KIISLMDSMFIKEPNKRPTAKMLLK 1485
HE + K YGA+ K+ IFM++ GGS+ L+ G DE +K Q ILE L +LH ++H DLK N+L+D++ KL D G S ++ +++ +P+ GT M+PE+ + + DIWSAA T+Y+M G+P + +L ++A P I ++ +C +I M SMF P RPTA LLK
Sbjct: 1 HENVVKLYGAVQTEQKIIIFMEYMDGGSVEMFLSN--NGSADEDSVKCVMQVILEALCWLHSKGVVHLDLKGGNVLMDSKGIVKLADFGASVHLDDTTTHTRNI-----------IPR---GTEAFMSPEVCRSEPFGRSTDIWSAACTLYQMLTGEPPWMQYSGGSILYQVAIATKPP----GIPDSLECSQEIKDFMASMFSFVPEDRPTAAELLK 198
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO42845 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0A9]) HSP 1 Score: 111.309 bits (277), Expect = 3.310e-27 Identity = 79/277 (28.52%), Postives = 132/277 (47.65%), Query Frame = 1
Query: 667 IDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCS-RFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G YG + K ++ AIK++ T+L ++I KE M++ + Y + KYYG+ K ++I M++ GS+ +L+ + L +E + K L+GL +LH R IH D+K+ NILL++E + KL D G + + +++ K + + GT MAPE+IQ + YD ADIWS T EM +G+P +A + + P ++ + + D K + +K P +R TA LL+ F
Sbjct: 30 LGEGSYGSVFKAMHKESGQVVAIKQVPVDTDLQEII----KEISMMQQCDSPY--------VVKYYGSYFKNTDLWIVMEYCGAGSVSDLMKIRNKTLTEEEIKCVLKYTLKGLEYLHLRRKIHRDIKAGNILLNSEGHAKLADFGVAGQLTDTMAKRN-----------------TVIGTPFWMAPEVIQEVGYDCLADIWSLGITAMEMAEGKPPYADIHPMRAIFMIPTKPPPTFRDPG-QWSEDFK--DFVSKCLVKNPEERATATELLQHSF 274
BLAST of Protein kinase vs. Ensembl Nematostella
Match: EDO49690 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RG02]) HSP 1 Score: 106.686 bits (265), Expect = 6.949e-26 Identity = 79/288 (27.43%), Postives = 142/288 (49.31%), Query Frame = 1
Query: 634 ICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAII--KGYKMYIFMDFYHGGSIYELLNTLPEGLP--DERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLK 1485
+ + ++ G+ I +G YG++ + + +KK+ D+ + +E E+ K S+L H I Y + G+ +YI M+F GG +Y L +G+P + +++++ QI L ++HE I+H DLK+QNI L K+ DLG +R +ES ++ + GT M+PE+ Y+ K+D+W+ +YEM + F K + ++ K+ KG+ P K + +TD + S++ SM ++P+KRP+A LL+
Sbjct: 1 MSLDRYTIGKCIGKGSYGEVFLSKHKKDKKQYVLKKV-------DLQKASVRERKAAELE-AKLLSQLRHPNIVSYRESFQDDTGF-LYIAMNFCEGGDLYSRLKA-QKGIPLDENQIVEWFVQIAMALQYMHEKHILHRDLKTQNIFLTKSKIIKVGDLGIARVLES----------------SSDMATTLIGTPYYMSPELFSNKPYNHKSDVWALGCCLYEMCTLRHAFNAKDMSSLVYKILKGKTPPLPK---QYSTD--LCSIIKSMLDQDPDKRPSASRLLR 257
BLAST of Protein kinase vs. Ensembl Medaka
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101156127]) HSP 1 Score: 132.88 bits (333), Expect = 7.161e-33 Identity = 90/284 (31.69%), Postives = 145/284 (51.06%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ +G+ + RG +G++ + + R A K++ + + + + + AL EI + K L H+RI +YYG + + K+ IF++F GGSI + L L ++ +YT+QIL+G+S+LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI +S GT M+PE+I G Y KAD+WS A T+ EM +P +A + + K+A K + E + +F++E RPTA +LL F
Sbjct: 327 WRQGKLLGRGAFGEVYLCYDADTGRELAAKQVPFDPDCQETSKEVN--ALECEIQLLK---NLRHDRIVQYYGCLRDLDQRKLTIFVEFMPGGSIKDQLKAY-GALTEKVTRRYTRQILQGVSYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRIQTIC-----MSGTGI--------KSVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAEYEAMAAIFKIAT----QPTKPTLPEGVSDASRDFLRQVFVEE-KWRPTADILLNHPF 586
BLAST of Protein kinase vs. Ensembl Medaka
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101156127]) HSP 1 Score: 132.88 bits (333), Expect = 8.858e-33 Identity = 90/284 (31.69%), Postives = 145/284 (51.06%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ +G+ + RG +G++ + + R A K++ + + + + + AL EI + K L H+RI +YYG + + K+ IF++F GGSI + L L ++ +YT+QIL+G+S+LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI +S GT M+PE+I G Y KAD+WS A T+ EM +P +A + + K+A K + E + +F++E RPTA +LL F
Sbjct: 357 WRQGKLLGRGAFGEVYLCYDADTGRELAAKQVPFDPDCQETSKEVN--ALECEIQLLK---NLRHDRIVQYYGCLRDLDQRKLTIFVEFMPGGSIKDQLKAY-GALTEKVTRRYTRQILQGVSYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRIQTIC-----MSGTGI--------KSVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAEYEAMAAIFKIAT----QPTKPTLPEGVSDASRDFLRQVFVEE-KWRPTADILLNHPF 616
BLAST of Protein kinase vs. Ensembl Medaka
Match: map3k22 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101156127]) HSP 1 Score: 132.88 bits (333), Expect = 8.858e-33 Identity = 90/284 (31.69%), Postives = 145/284 (51.06%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAI--IKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ +G+ + RG +G++ + + R A K++ + + + + + AL EI + K L H+RI +YYG + + K+ IF++F GGSI + L L ++ +YT+QIL+G+S+LH N I+H D+K NIL D+ N KL D G S+ I+++ S GI +S GT M+PE+I G Y KAD+WS A T+ EM +P +A + + K+A K + E + +F++E RPTA +LL F
Sbjct: 357 WRQGKLLGRGAFGEVYLCYDADTGRELAAKQVPFDPDCQETSKEVN--ALECEIQLLK---NLRHDRIVQYYGCLRDLDQRKLTIFVEFMPGGSIKDQLKAY-GALTEKVTRRYTRQILQGVSYLHSNMIVHRDIKGANILRDSSGNVKLGDFGASKRIQTIC-----MSGTGI--------KSVTGTPYWMSPEVINGEGYGRKADVWSVACTVVEMLTQKPPWAEYEAMAAIFKIAT----QPTKPTLPEGVSDASRDFLRQVFVEE-KWRPTADILLNHPF 616
BLAST of Protein kinase vs. Ensembl Medaka
Match: map3k2 (mitogen-activated protein kinase kinase kinase 2 [Source:NCBI gene;Acc:101160297]) HSP 1 Score: 127.872 bits (320), Expect = 4.406e-31 Identity = 91/285 (31.93%), Postives = 143/285 (50.18%), Query Frame = 1
Query: 658 GQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAK----GELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
G+ + +G +G++ + + R A+K++ + + + + AL EI + K L HERI +YYG + + + IFM+ GGSI + L + L + +YT+QILEG+S+LH N I+H D+K NIL D+ N KL D G SR ++++ S GI +S GT M+PE+I G Y KADIWS T+ EM +P +A + + K+A ELP + +E + +F+ E +RP+A LL+ F
Sbjct: 392 GKLLGQGAFGRVYLCYDADTGRELAVKQVQFDPESPETSKEVS--ALECEIQLLK---NLCHERIVQYYGCLRDTMERTLSIFMEHMPGGSIKDQLKSY-GALTENVTRRYTRQILEGVSYLHSNMIVHRDIKGANILRDSVGNVKLGDFGASRRLQTICL-----SGTGI--------KSVTGTPYWMSPEVISGEGYGRKADIWSVGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPELPVHVSDHCRE--------FLRRIFV-ETKQRPSADELLRHIF 648
BLAST of Protein kinase vs. Ensembl Medaka
Match: map3k3 (mitogen-activated protein kinase kinase kinase 3 [Source:NCBI gene;Acc:101169290]) HSP 1 Score: 124.02 bits (310), Expect = 7.325e-30 Identity = 88/288 (30.56%), Postives = 142/288 (49.31%), Query Frame = 1
Query: 649 FSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYK--MYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGE----LPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
+ G+ + +G +G + + R A K++ + + + + + AL EI + K L HERI +YYG + + + IFM++ GGS+ + L L + KYT+QILEG+S+LH N I+H D+K NIL D+ N KL D G S+ ++++ S GI +S GT M+PE+I G Y KAD+WS T+ EM +P +A + + K+A LP + + ++ C +F+ E RP+A+ LL+ F
Sbjct: 353 WRRGKLLGQGAFGLVYLCYDVDTGRELAAKQVQFDPDSPETSKEVS--ALECEIQLLK---NLHHERIVQYYGCLRDHSEKTLTIFMEYMPGGSVKDQLKAY-GALTENVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM-----SGTGI--------RSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPLLPSHTSDQARDFIHC--------IFV-EAKHRPSAEELLRHPF 612
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000024804.1 (SMESG000024804.1) HSP 1 Score: 897.116 bits (2317), Expect = 0.000e+0 Identity = 435/441 (98.64%), Postives = 437/441 (99.09%), Query Frame = 1
Query: 187 MLDSKRYSAFIESLKYGDLPTVEQEFQPIFLNQPDSSGYLPLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDEILQDLINRPDYQDVKNIITTAIKNYQVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYFDINIL 1509
MLDSKRYSAFIESLKYGDLPTVEQEFQPIFLNQPDSSGYLPLHIASQGSN EVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDEILQDLINRP+YQDVKNIIT AIKNYQVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFI+RGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVE NINKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNT PEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYFDINIL
Sbjct: 1 MLDSKRYSAFIESLKYGDLPTVEQEFQPIFLNQPDSSGYLPLHIASQGSNLEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDEILQDLINRPNYQDVKNIITNAIKNYQVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFIERGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVETNINKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTFPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYFDINIL 441
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000016834.1 (SMESG000016834.1) HSP 1 Score: 201.445 bits (511), Expect = 3.625e-58 Identity = 138/404 (34.16%), Postives = 209/404 (51.73%), Query Frame = 1
Query: 307 PLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCEL-SMNDEILQDLINRPDYQDVKNIITTAIKNYQVGKE---MDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENV-VLMKLA---KGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKTYF 1494
P+H+AS E+LK L+ C++E RPIHFA N + +++L C++ + D L ++ +D+ N++ A++ Q+ ++ M L+CN +CDHK C S+ +F G+ I G +G + SG R FAIK I++ K + +E+NIN + L + RI +Y+GAI ++ IFM+F GS+ + ++ PD +++Y++QILEGL FLH +IIH DLK NIL+D E+N KL D G SR + + GI + K L GT N APE++ G Y++ ADIWS ATI M QP + + + V+ K+ K ELP I E I+ L+ +P RPTA LLK+ F
Sbjct: 146 PVHLASAHGQAEILKVLIDNKCDLEICADKNLRPIHFACANDRVEVLQILIDHNCDIEACADFNLSPMVIAEGNKDLINMLNAAVEARQLRQQISAMGLQCNSQCDHKLCPISLESKKFHRGEEIGHGAFGTVFHCKGSGIDRSFAIKFISYT----------KFDKRNIELNINSFLPMLKNARIVQYFGAIKTESELCIFMEFLPLGSLNDKISRERSIKPD-NIIRYSRQILEGLEFLHGKKIIHRDLKPGNILMDDENNIKLADFGISRLLIRTD---------GISIDTKSLA----GTPNFTAPEIMSGDPYNVPADIWSLGATIINMITSQPPYHNLETPLAVVFKIGNEKKLELPS----DISEEMRIFILDLLQP----DPKDRPTAAELLKSKF 517 HSP 2 Score: 54.299 bits (129), Expect = 1.517e-7 Identity = 35/146 (23.97%), Postives = 71/146 (48.63%), Query Frame = 1
Query: 178 TCLMLDSKRYSAFIESLKYGDLPTVEQEFQPIFLNQPDSSGYLPLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDEILQDLINRPDYQDVKNIIT---TAIKNYQVGKEMDLKCNLE 606
+C +D + FI++++ + + + F+ +LN D + LP+HIA + ++++ L+ + C++E+ RP+HFA +++ +K+L C + + N+ +Q V T I + + D KCNLE
Sbjct: 6 SCSSID--EFELFIDAVERNSVKSFSEYFKSEYLNSKDKNSMLPIHIACYEGHTQMVQMLISKKCDLEACTKYNCRPVHFACARGHLDILKILVNQNCNIHSH--------NKDHWQPVHLACACGHTGILQFLI----DQKCNLE 137
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000017215.1 (SMESG000017215.1) HSP 1 Score: 196.052 bits (497), Expect = 2.599e-57 Identity = 140/415 (33.73%), Postives = 216/415 (52.05%), Query Frame = 1
Query: 307 PLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSM---NDEILQDLINRPDYQDVKNIIT------------TAIKNYQVGKEMDLKCNLECDHK-FCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSI-YELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKF-GTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKG---ELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKT 1488
P+H+A N ++K L+ + CNIES D + W+PIH A ++ ++LL C+++ N + L + YQ + +++ ++ ++ + M +KC L C HK C SI F +G + G +G + K+ +G ++ FA+K IN IE++++ +E I+++ L H RI KY+GAI K+ IFM+++ SI +++ G+ D +++YTKQI+EGL FLH +IIH DLK NILL+ EDN KLTD G SR SL K GI +P F GTAN APE+I Y ADIWS AA++ M G+P + G + VL K++ E+PD +K + SM +P++RP+A LLK+
Sbjct: 12 PMHLACDMGNIYIVKLLIDEKCNIESCDKDNWQPIHLACARGHVEIVRLLMQEKCDIAAVNRNGDSPMKLARKYQYQAIIDLLNERQSELERVWSLKTQESERLIEMMGVKCTLLCTHKQLCPNSIRSKTFPKGTKVGHGSFGDVCKMKGTGTNKEFALKYIN--------IEDIERR--YIEGRIDEFIPVLDHPRIIKYFGAIETEKKLCIFMEYFPNNSIQHKIKEEGCIGITD--VVRYTKQIIEGLEFLHGKKIIHRDLKPDNILLNNEDNIKLTDFGLSR---SLIK------TGGIT-----IPARTFVGTANFTAPEIINSEPYREPADIWSVAASMINMITGKPPYHGFQSVTVLFKISSTKTIEMPDSISDEMK--------GFILSMLNPDPSERPSATNLLKS 392
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000017215.1 (SMESG000017215.1) HSP 1 Score: 192.971 bits (489), Expect = 2.373e-56 Identity = 139/414 (33.57%), Postives = 215/414 (51.93%), Query Frame = 1
Query: 310 LHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSM---NDEILQDLINRPDYQDVKNIIT------------TAIKNYQVGKEMDLKCNLECDHK-FCLTSICFNEFSEGQFIDRGRYGKISKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSI-YELLNTLPEGLPDERLLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKF-GTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKG---ELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLKT 1488
+H+A N ++K L+ + CNIES D + W+PIH A ++ ++LL C+++ N + L + YQ + +++ ++ ++ + M +KC L C HK C SI F +G + G +G + K+ +G ++ FA+K IN IE++++ +E I+++ L H RI KY+GAI K+ IFM+++ SI +++ G+ D +++YTKQI+EGL FLH +IIH DLK NILL+ EDN KLTD G SR SL K GI +P F GTAN APE+I Y ADIWS AA++ M G+P + G + VL K++ E+PD +K + SM +P++RP+A LLK+
Sbjct: 1 MHLACDMGNIYIVKLLIDEKCNIESCDKDNWQPIHLACARGHVEIVRLLMQEKCDIAAVNRNGDSPMKLARKYQYQAIIDLLNERQSELERVWSLKTQESERLIEMMGVKCTLLCTHKQLCPNSIRSKTFPKGTKVGHGSFGDVCKMKGTGTNKEFALKYIN--------IEDIERR--YIEGRIDEFIPVLDHPRIIKYFGAIETEKKLCIFMEYFPNNSIQHKIKEEGCIGITD--VVRYTKQIIEGLEFLHGKKIIHRDLKPDNILLNNEDNIKLTDFGLSR---SLIK------TGGIT-----IPARTFVGTANFTAPEIINSEPYREPADIWSVAASMINMITGKPPYHGFQSVTVLFKISSTKTIEMPDSISDEMK--------GFILSMLNPDPSERPSATNLLKS 380
BLAST of Protein kinase vs. Planmine SMEST
Match: SMESG000022974.1 (SMESG000022974.1) HSP 1 Score: 193.356 bits (490), Expect = 3.857e-55 Identity = 131/403 (32.51%), Postives = 206/403 (51.12%), Query Frame = 1
Query: 307 PLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSM---NDEILQDLINRPDYQDVKNIITTAIKNY---QVGKEMDLKCNLECDHKFCLTSICFNEFSEGQFIDRGRYGKI--SKIFQSGGSRIFAIKKINWKTNLNDVIENLKKEALMVEININKYRSELVHERITKYYGAIIKGYKMYIFMDFYHGGSIYELLNTLPEGLPDER--LLKYTKQILEGLSFLHENRIIHGDLKSQNILLDTEDNCKLTDLGCSRFIESLNKYSQKHSKAGIQMKHKELPQSKFGTANNMAPEMIQGLSYDLKADIWSAAATIYEMFDGQPLFAGKKENVVLMKLAKGELPDYKKHRIKENTDCKIISLMDSMFIKEPNKRPTAKMLLK 1485
P+HI+ + + ++K L+ NCNIE++D + WRPIH+A N+ +LL C L M N++ ++ + Y DV +I +K ++ + + + D + S C N+F++ + I RG +GK+ K+ +SG F +K +T+ ++ M+E NIN+Y L HERI YYG + K K YI M++ GS LLN + + + R ++ +KQI+EG+ FLH N+IIH D+ NILLD N KLTD G SR ++ G Q ++ GT N +APE+I Y ADIWS ATI+ M G+ LF K ++ + K + D+K + ++ +++ M +P+ RPTA LLK
Sbjct: 130 PIHISCRYGHTNIVKLLIENNCNIEARDYSKWRPIHWACYVGNVEVARLLITNKCTLDMLTKNNKTPINIAEQYRYTDVMKVIQDELKRQLFDRISRAFQVSNDFNLDQD--IYSKCSNDFAKVRCIGRGSFGKVILYKLLKSGHE--FVVKSTYIETD----------DSRMIENNINRYIDLLNHERIVSYYGVVQKAKKFYILMEYMPQGS---LLNCIEKTMSILRKQIINVSKQIIEGVEFLHGNQIIHRDITPSNILLDANLNIKLTDFGFSRVVKD----------TGTQ----NCAKTFCGTINYLAPEIISDQQYSFPADIWSVGATIFHMLLGRELFHEKSICEIVTFILKNKKIDFKPLELSSR---RMSTIVKEMLNYKPSNRPTAASLLK 498 HSP 2 Score: 62.003 bits (149), Expect = 4.835e-10 Identity = 31/92 (33.70%), Postives = 52/92 (56.52%), Query Frame = 1
Query: 217 IESLKYGDLPTVEQEFQPIFLNQPDSSGYLPLHIASQGSNHEVLKFLLGQNCNIESKDSNGWRPIHFAVLNKNMNNIKLLFGFGCELSMNDE 492
+ +K G + V+ F P +LN+ D + P+H+A + + EV+KFL+ + IES GWRPI FA N + + + +L CE++ D+
Sbjct: 1 MSKVKLGIIDEVKISFMPEYLNKIDMNFDEPIHVACENGHEEVVKFLIDKGAKIESHRKFGWRPIFFACFNCHKDVLMILIKNRCEINALDQ 92 The following BLAST results are available for this feature:
BLAST of Protein kinase vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Protein kinase vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Protein kinase vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Protein kinase vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Protein kinase vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Protein kinase vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Protein kinase vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Protein kinase vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035101 ID=SMED30035101|Name=Protein kinase|organism=Schmidtea mediterranea sexual|type=transcript|length=1515bpback to top protein sequence of SMED30035101-orf-1 >SMED30035101-orf-1 ID=SMED30035101-orf-1|Name=SMED30035101-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=442bp MLDSKRYSAFIESLKYGDLPTVEQEFQPIFLNQPDSSGYLPLHIASQGSNback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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