DNA-dependent protein kinase catalytic subunit
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30035077 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 6
Homology
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413]) HSP 1 Score: 368.237 bits (944), Expect = 9.824e-101 Identity = 250/829 (30.16%), Postives = 419/829 (50.54%), Query Frame = 2
Query: 9800 LGDCYWTLGNVLSLHWQSEP------ENKIINSILELIDHTGDYTKDS--LICGLLNKSFYCFNKIISMY-------SESDGNKKELSAALVVVSDFYDAQIRQFENDGP--------SRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY---KKVSSEFYTQYFP------NTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
LG Y + N LS SEP E ILEL +G ++DS +I GL ++F ++ + S S G + A + ++DF D Q+R+ E + + P L+ VE L ++KL A+ KFPRLLQII ++ + + +T SS+P W +I W+ M+ LD + V+ + I D+YP A+ YPF++ Y TS + F+ +I L ++ F AL Q+ PE + W +ND+ + + +++NI Y+ MY +G+ G F+ +F + F + +F + G+ + + + F++I N + L NLK+ SPW++ + ++ LEIPGQY+ +P PE H++I + + +M S + PK+III G +E+ + FLVK GEDLRQD R+EQ+F VMN I+++D ++ +AL ++TY+V+P++ LGL+EW++NTVTL + TM EE+ Y + Y + + AY ++ ++ T F + ++ + DLL+++F+ +S E+F LR +F +A+ +H++LGIGDRHL NF++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT + + P G+ + + L + + + M VF+ DW +M + I+ + +++I + RKL +P ++ +EL + + K+ F+ N ++++ E+ +Q K L+ AT+ L RTW+G+EP
Sbjct: 3330 LGTTYRIIANALS----SEPACLAEIEEDKARRILEL---SGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQQLRKEEENASVIDSAELQAYPALV---VEKMLKALKLNSNEARLKFPRLLQIIERYPEETL--SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDW---SNDVRAELAKTPVNKKNIEKMYERMY-AALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFNDITNML---LLKMNKDSKPPGNLKECSPWMSDFKVE--------FLRNELEIPGQYDG-RGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQ--RALQ-LRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPA-DLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEP 4126 HSP 2 Score: 238.039 bits (606), Expect = 2.223e-61 Identity = 301/1297 (23.21%), Postives = 569/1297 (43.87%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMDSGY-RFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV-----PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSY-AALSTRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK-----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERW-IKAFPH-MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMG--INYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT----WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRI---VPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNA---IFWMNTLEASVQSFCWL-LSMNLIDAYNYF-------------TKGVSNLFTAVNNFL 4027
E F+ ++ +K+ P+ IKN + V +K +AK K +L IK LQ + + F+ IG S + +L + K TVL + EL+G + ++P+ + + + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ +LK + R+A + L H + + + +F +LK H NV LK +A + L+ +L+ + + A N + + +Y QF ++ + S +K L I+G G C V+ K+ + +Y + + + +L + D R +P + + +A +L+ L + + +L++ ++ + F ++SP++ ++ R I + L A V + I +V+Q +I CS PV P S S + ++ + T + DL + ++ D + A N + + L++D F+K KI+++LDL + + V ++ +DP + PKDF F+NL + + + + W L+ +S LPL+SGFYK++ ++ +F+ ++ + K + D A+F + K+ Y DELL +CLT L++ P I ++ + P LQMA +LG Y PL + L+ LE W I H M + K ILP L S +S + + + L A++G K+ L+ ++ + S +A+ LE+++ R++++LG +G IN + + + + W++ E + + +PF+++KP I L+ + ++ LAL ++ Q K A E+LHS+++ +LGK AT + E + P + F + ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD G+ + FLK S K I +K K +R+Y L + + +KRLGA FN+I+ + + L+E +F + +E L+ D K LGTI Q A ++ L K R+ PPS + ++ ++WLL + + R I+L + + +PN + K +L + + ++ FE + PS + A + ++ + + CWL L + ++ YN F T+ S+L AV FL
Sbjct: 83 EEILKFLCIFLEKMGQKIAPYSVEIKNTCTS-VYTKDRAAKCKIPALDLLIKLLQTFRSSRLMDEFK--IGELFSKFYGELALKKKIPDTVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE--DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKWCAHTNVELKKAALSALESFLKQVSNMV----AKN--AEMHKNKLQYFMEQFYGIIRNVDS-----NNKELSIAIRGYGLFAGPCKVINAKD-VDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSF-LQSVASVLLYLDTVPEVYTP-----VLEH-----LVVMQIDSFPQYSPKM---QLVCCRAIVKVFL-ALAAKGPVLRNCISTVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQMMDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGVWMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRLPLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAV---KMKQYKDELLASCLTFLLSLPHNIIELDVRAYVP-------ALQMAFKLGLSYTPLAEVGLNALEEWSIYIDRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSR--AAQKGFNKV--VLKHLKKTKNLSSNEAI-----------SLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDR--EKRLSFAVPFREMKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGK-ATQM--PEGGQGAPPMYQLYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGI-------------VDPVDSTL-RDFCGRCIREFLKWSI--KQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASLAFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEKKHVSLNKAKKRRLPRGFPPSASLCLLDL-VKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNRSPNLWLKDVLKEEGVSFLINTFEGGGCGQ--PSGILAQPTLLYLRGPFSLQATLCWLDLLLAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFL 1298 HSP 3 Score: 187.578 bits (475), Expect = 4.610e-46 Identity = 277/1298 (21.34%), Postives = 544/1298 (41.91%), Query Frame = 2
Query: 4889 IDLLLEMMLIDSNICENNF------IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENI-KTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLL-ALFE----DELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL--------IGELSKICSLILYCKSDDSTNKLIY--QMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLM-----------IINIPYDIVNDHPCMDTFICL-HHQMKNVGIIS--EVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNG---YLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFF--QLFVDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQ-----ELRSYSMSHDQKFKVPTSINIPKQAKN------------FDWIQLASTLQF-----PSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQEN----QTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFV 8518
+ LL +++ IDS++ N +F + +LL+ T L + K + + + F T G S + + + + +F S++ Y++ + L++ ++ ++ + CRE H E+ + + + + R ++ LL +++E D+ +L ++ F+++ ++ C + L FF + + ++ +K + F NE I KI+ +Y+ L +D V +E K+ I E +++ ++ D T + Q++ R + A+NC SV+ ++ KFY L KP +F ++I NFP E+ + ++ K+ + KE + +++ P + S +L+DS+L+ ++ + + S V S S GR ++ + D +N H CM L H +++G E + D+PSWMK H ++I+ F+ KL+IN +F+PYA W+ L++ + I+ V ++ I+ W+ + V K + N L+N+L ++ + ++ R N+E+ +L+ WK+ + IPY+ IF+ + N G+++L V+ N Y G + F + + + K V+ A E+ G++L+ +++ + E + E+ + + + + F+ CL + K+ + R ++ + +L LE++ C + E L+ QL + + ++++ + + ++ + + + +N VV+ P +T E+ L + + D SE + + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMTS PD+ P+F+ H S F+ T + L P FV + R+ S ++ V I +Q + FDW+ +ST PS + +K ++ + + G D K L L ++N+ K + + + + F + + Y ++ + REK ++ + K +++ V LYR+Y G LP+I+I++ S I PLQ +AQ + +K LF L++G+LKE + F Q L Q F+ L T +S I+ + + ++L+P+ V
Sbjct: 1646 LALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLKGQAVTLLPFF----TSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALEL-----SQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLESVYEMFRKDDPRLSFTRQS---FVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLK-SRFTKLNESTFDTQITKKMGYYKILDVMYSRL----PKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCYDAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFS-EKPEKNLLIFENLIDLKRRYNFPVEVEVPMERKKKYIEIRKEA------REAANGDSDGPSYMSSLSYLADSTLSEEMSQFD--FSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTALVKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGL-ATPTGVPKDEVLANRLLNFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIVMANDLPPYDPQCGIQSSEYFQALVNNMSFVR--YKEVYAAAAEVLGLILRYVMERKNILEESLCEL---VAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEVVLCRVEGMTE---LYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNP-VVEFVSH--PSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTSMSPDYPNPMFE-HPLSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG------KKRLGLPGD--EVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL---------KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAV 2876
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:HGNC Symbol;Acc:HGNC:9413]) HSP 1 Score: 335.495 bits (859), Expect = 8.336e-91 Identity = 238/820 (29.02%), Postives = 403/820 (49.15%), Query Frame = 2
Query: 9800 LGDCYWTLGNVLSLHWQSEP------ENKIINSILELIDHTGDYTKDS--LICGLLNKSFYCFNKIISMY-------SESDGNKKELSAALVVVSDFYDAQIRQFENDGP--------SRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
LG Y + N LS SEP E ILEL +G ++DS +I GL ++F ++ + S S G + A + ++DF D Q+R+ E + + P L+ VE L ++KL A+ KFPRLLQII ++ + + +T SS+P W +I W+ M+ LD + V+ + I D+YP A+ YPF++ Y TS + F+ +I L ++ F AL Q+ PE + W +ND+ + + +++NI Y+ MY +G+ G F+ +F + F + +F + G+ + + + F++I N + L NLK+ SPW++ + ++ LEIPGQY+ +P PE H++I + + +M S + PK+III G +E+ + FLVK GEDLRQD R+EQ+F VMN I+++D ++ +AL ++TY+V+P++ S + L++ GK + AY ++ ++ T F + ++ + DLL+++F+ +S E+F LR +F +A+ +H++LGIGDRHL NF++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT + + P G+ + + L + + + M VF+ DW +M + I+ + +++I + RKL +P ++ +EL + + K+ F+ N ++++ E+ +Q K L+ AT+ L RTW+G+EP
Sbjct: 3330 LGTTYRIIANALS----SEPACLAEIEEDKARRILEL---SGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQQLRKEEENASVIDSAELQAYPALV---VEKMLKALKLNSNEARLKFPRLLQIIERYPEETL--SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDW---SNDVRAELAKTPVNKKNIEKMYERMY-AALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFNDITNML---LLKMNKDSKPPGNLKECSPWMSDFKVE--------FLRNELEIPGQYDG-RGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQ--RALQ-LRTYSVVPMTSSDPRAPPCEYKDWLTKMSGKH----------------------DVGAYMLMYKGANRTETVTSFRKRESKVPA-DLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEP 4095 HSP 2 Score: 238.81 bits (608), Expect = 1.330e-61 Identity = 301/1297 (23.21%), Postives = 569/1297 (43.87%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMDSGY-RFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV-----PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSY-AALSTRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK-----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERW-IKAFPH-MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMG--INYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT----WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRI---VPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNA---IFWMNTLEASVQSFCWL-LSMNLIDAYNYF-------------TKGVSNLFTAVNNFL 4027
E F+ ++ +K+ P+ IKN + V +K +AK K +L IK LQ + + F+ IG S + +L + K TVL + EL+G + ++P+ + + + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ +LK + R+A + L H + + + +F +LK H NV LK +A + L+ +L+ + + A N + + +Y QF ++ + S +K L I+G G C V+ K+ + +Y + + + +L + D R +P + + +A +L+ L + + +L++ ++ + F ++SP++ ++ R I + L A V + I +V+Q +I CS PV P S S + ++ + T + DL + ++ D + A N + + L++D F+K KI+++LDL + + V ++ +DP + PKDF F+NL + + + + W L+ +S LPL+SGFYK++ ++ +F+ ++ + K + D A+F + K+ Y DELL +CLT L++ P I ++ + P LQMA +LG Y PL + L+ LE W I H M + K ILP L S +S + + + L A++G K+ L+ ++ + S +A+ LE+++ R++++LG +G IN + + + + W++ E + + +PF+++KP I L+ + ++ LAL ++ Q K A E+LHS+++ +LGK AT + E + P + F + ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD G+ + FLK S K I +K K +R+Y L + + +KRLGA FN+I+ + + L+E +F + +E L+ D K LGTI Q A ++ L K R+ PPS + ++ ++WLL + + R I+L + + +PN + K +L + + ++ FE + PS + A + ++ + + CWL L + ++ YN F T+ S+L AV FL
Sbjct: 83 EEILKFLCIFLEKMGQKIAPYSVEIKNTCTS-VYTKDRAAKCKIPALDLLIKLLQTFRSSRLMDEFK--IGELFSKFYGELALKKKIPDTVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE--DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKWCAHTNVELKKAALSALESFLKQVSNMV----AKN--AEMHKNKLQYFMEQFYGIIRNVDS-----NNKELSIAIRGYGLFAGPCKVINAKD-VDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSF-LQSVASVLLYLDTVPEVYTP-----VLEH-----LVVMQIDSFPQYSPKM---QLVCCRAIVKVFL-ALAAKGPVLRNCISTVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQMMDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGVWMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRLPLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAV---KMKQYKDELLASCLTFLLSLPHNIIELDVRAYVP-------ALQMAFKLGLSYTPLAEVGLNALEEWSIYIDRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSR--AAQKGFNKV--VLKHLKKTKNLSSNEAI-----------SLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDR--EKRLSFAVPFREMKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGK-ATQM--PEGGQGAPPMYQLYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGI-------------VDPVDSTL-RDFCGRCIREFLKWSI--KQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASLAFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEKKHVSLNKAKKRRLPRGFPPSASLCLLDL-VKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNRSPNLWLKDVLKEEGVSFLINTFEGGGCGQ--PSGILAQPTLLYLRGPFSLQATLCWLDLLLAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFL 1298 HSP 3 Score: 187.963 bits (476), Expect = 3.103e-46 Identity = 277/1298 (21.34%), Postives = 544/1298 (41.91%), Query Frame = 2
Query: 4889 IDLLLEMMLIDSNICENNF------IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENI-KTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLL-ALFE----DELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL--------IGELSKICSLILYCKSDDSTNKLIY--QMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLM-----------IINIPYDIVNDHPCMDTFICL-HHQMKNVGIIS--EVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNG---YLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFF--QLFVDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQ-----ELRSYSMSHDQKFKVPTSINIPKQAKN------------FDWIQLASTLQF-----PSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQEN----QTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFV 8518
+ LL +++ IDS++ N +F + +LL+ T L + K + + + F T G S + + + + +F S++ Y++ + L++ ++ ++ + CRE H E+ + + + + R ++ LL +++E D+ +L ++ F+++ ++ C + L FF + + ++ +K + F NE I KI+ +Y+ L +D V +E K+ I E +++ ++ D T + Q++ R + A+NC SV+ ++ KFY L KP +F ++I NFP E+ + ++ K+ + KE + +++ P + S +L+DS+L+ ++ + + S V S S GR ++ + D +N H CM L H +++G E + D+PSWMK H ++I+ F+ KL+IN +F+PYA W+ L++ + I+ V ++ I+ W+ + V K + N L+N+L ++ + ++ R N+E+ +L+ WK+ + IPY+ IF+ + N G+++L V+ N Y G + F + + + K V+ A E+ G++L+ +++ + E + E+ + + + + F+ CL + K+ + R ++ + +L LE++ C + E L+ QL + + ++++ + + ++ + + + +N VV+ P +T E+ L + + D SE + + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMTS PD+ P+F+ H S F+ T + L P FV + R+ S ++ V I +Q + FDW+ +ST PS + +K ++ + + G D K L L ++N+ K + + + + F + + Y ++ + REK ++ + K +++ V LYR+Y G LP+I+I++ S I PLQ +AQ + +K LF L++G+LKE + F Q L Q F+ L T +S I+ + + ++L+P+ V
Sbjct: 1646 LALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLKGQAVTLLPFF----TSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALEL-----SQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLESVYEMFRKDDPRLSFTRQS---FVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLK-SRFTKLNESTFDTQITKKMGYYKILDVMYSRL----PKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCYDAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFS-EKPEKNLLIFENLIDLKRRYNFPVEVEVPMERKKKYIEIRKEA------REAANGDSDGPSYMSSLSYLADSTLSEEMSQFD--FSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTALVKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGL-ATPTGVPKDEVLANRLLNFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIVMANDLPPYDPQCGIQSSEYFQALVNNMSFVR--YKEVYAAAAEVLGLILRYVMERKNILEESLCEL---VAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEVVLCRVEGMTE---LYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNP-VVEFVSH--PSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTSMSPDYPNPMFE-HPLSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG------KKRLGLPGD--EVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL---------KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAV 2876
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: MTOR (mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942]) HSP 1 Score: 157.918 bits (398), Expect = 3.708e-38 Identity = 143/578 (24.74%), Postives = 260/578 (44.98%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLF--EADIKDNFR---------EDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFS-PWLAKYN-FRD-------------SYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNF--DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ + +N + S + + +M+ + + EE S+L+ E ++K F E G TL + F++ R + + W K + N+KD + W Y+ FR Y P ++ +D L +PG Y+ +P I+I + P +Q++ SKQ P+K+ ++G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ D ++ QK E ++ ++N D L K S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 137 IDTWLQV--IPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNM-----------------------CEHSNTLVQQAMMVSEELIRVAILWHEMWHEGL------------EEASRLYFGERNVKGMFEVLEPLHAMMERGPQ--TLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYD--PNQPI----IRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND---PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPD----------YDHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTR 650
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: MTOR (mechanistic target of rapamycin kinase [Source:HGNC Symbol;Acc:HGNC:3942]) HSP 1 Score: 158.303 bits (399), Expect = 2.604e-37 Identity = 143/578 (24.74%), Postives = 260/578 (44.98%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLF--EADIKDNFR---------EDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFS-PWLAKYN-FRD-------------SYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNF--DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ + +N + S + + +M+ + + EE S+L+ E ++K F E G TL + F++ R + + W K + N+KD + W Y+ FR Y P ++ +D L +PG Y+ +P I+I + P +Q++ SKQ P+K+ ++G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ D ++ QK E ++ ++N D L K S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 1932 IDTWLQV--IPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNM-----------------------CEHSNTLVQQAMMVSEELIRVAILWHEMWHEGL------------EEASRLYFGERNVKGMFEVLEPLHAMMERGPQ--TLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYD--PNQPI----IRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND---PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDY----------DHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTR 2445
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: ATM (ATM serine/threonine kinase [Source:HGNC Symbol;Acc:HGNC:795]) HSP 1 Score: 145.976 bits (367), Expect = 1.452e-33 Identity = 96/317 (30.28%), Postives = 164/317 (51.74%), Query Frame = 2
Query: 10907 GQYNN-ITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVV---STNQKFEENQNLISNFDLLRKSFMTISKCHESF------YRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
G+Y N +T + F + F+L G+ + PK I +G + + LVK +DLRQD ++Q+F + N ++ ++ T++ K I TY V+P+S+ G+LEW TV + EF + + E +K+ Y PN + + +K V S +K+E ++ NF + + F C E F + R+ + + A + Y+LG+GDRH++N LINE + +++ ID G AF I LP PE +PFRLT +V+ + +GV G+F + + + + Q T+++I+ V L + + DW
Sbjct: 2675 GEYGNLVTIQSFKAE----FRLAGGVNL------PKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRN---TETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEF----LVNNEDGAHKR--------YRPNDFSAFQCQKKMMEVQKKSFEEKYEVFMDVCQNFQPVFRYF-----CMEKFLDPAIWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQETLLTIVEVLLYDPLFDW 2960
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95]) HSP 1 Score: 169.474 bits (428), Expect = 3.995e-41 Identity = 146/575 (25.39%), Postives = 262/575 (45.57%), Query Frame = 2
Query: 10172 RLLQIINQHALDI-FDFNF-LTAIFSSIPSWMYIPWLDQMIPFLDCPISH----IVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRD-SYYQPDVISKDWLE--IPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSK 11851
RL+Q+ H D D F LT +P ++ + Q++ LDCP +V ++ IA P A+ Y L VA + + G +L + KLV + ++ + + + W D +D HD+N Q M+ + D ++KG F+ + +E G + Q E + + + W++ S FK L+D LA N D Y P+++S LE +PG Y+ + P + I + ++ SKQ P+K++I G N Y FL+K ED RQD R+ Q+F ++N +++ + + + + L+ I+ Y+++ +SK GL+ W+ N TL ++Y KK ++ + E ++ Q FE ++ DL R S E ++ R N+ + A Y+LG+GDRH N +++ TG ++ IDFG F +A + PE +PFRLT ++ ++ +G+ G+++ T + VL L Q ++++++ F+ + +++W + M K
Sbjct: 2072 RLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIY--ALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHDNN--------VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYV------QAFESSGNVKDLNQAWEIYCSVFKKLRD---QLATLNSLDLVYVSPNLVSAKDLELVVPGTYD--PSAPI----VSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCR--RNLT-IQRYSIVALSKDSGLIGWVPNCDTLHTLV-------KEYREKKAKIPLSIEH-KTLQKLSLETEHLTLMQKLQLFESALSVTQGEDL-RHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKK 2609
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: let-363 (Target of rapamycin homolog [Source:UniProtKB/Swiss-Prot;Acc:Q95Q95]) HSP 1 Score: 169.474 bits (428), Expect = 4.064e-41 Identity = 146/575 (25.39%), Postives = 262/575 (45.57%), Query Frame = 2
Query: 10172 RLLQIINQHALDI-FDFNF-LTAIFSSIPSWMYIPWLDQMIPFLDCPISH----IVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRD-SYYQPDVISKDWLE--IPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSK 11851
RL+Q+ H D D F LT +P ++ + Q++ LDCP +V ++ IA P A+ Y L VA + + G +L + KLV + ++ + + + W D +D HD+N Q M+ + D ++KG F+ + +E G + Q E + + + W++ S FK L+D LA N D Y P+++S LE +PG Y+ + P + I + ++ SKQ P+K++I G N Y FL+K ED RQD R+ Q+F ++N +++ + + + + L+ I+ Y+++ +SK GL+ W+ N TL ++Y KK ++ + E ++ Q FE ++ DL R S E ++ R N+ + A Y+LG+GDRH N +++ TG ++ IDFG F +A + PE +PFRLT ++ ++ +G+ G+++ T + VL L Q ++++++ F+ + +++W + M K
Sbjct: 2075 RLMQLWFDHGDDKDQDVYFALTETIFDLPVTTWLEAIPQLMARLDCPDDQKSVQLVLRVLCEIARHRPQAVIY--ALTVASRSKDVHRSKNAGTVLEKMMEYHSKLVREASLVTEELVRCAILWHEQWHDALDDASRVYFHDNN--------VQAMFDALRNMNDLMQKGAPTTMKEHSFQQTYSSDLKEAGRYV------QAFESSGNVKDLNQAWEIYCSVFKKLRD---QLATLNSLDLVYVSPNLVSAKDLELVVPGTYD--PSAPI----VSIQSFSSKMNVITSKQRPRKMVIRGSNGLDYQFLLKGHEDPRQDERVMQLFGLVNTLLANNSETCR--RNLT-IQRYSIVALSKDSGLIGWVPNCDTLHTLV-------KEYREKKAKIPLSIEH-KTLQKLSLETEHLTLMQKLQLFESALSVTQGEDL-RHVLWLKSPSSEVWFDRRTNYTRSVACMSMVGYILGLGDRHPSNLMLDRLTGKVVHIDFGDCFEVAMLREKFPERVPFRLTRMLINAMEVTGLDGVYNYTAERVLKMLRTNQESLLAVLEAFVYDPVINWRLVEGMKK 2612
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: smg-1 (Serine/threonine-protein kinase smg-1 [Source:UniProtKB/Swiss-Prot;Acc:O01510]) HSP 1 Score: 125.561 bits (314), Expect = 7.069e-28 Identity = 152/666 (22.82%), Postives = 271/666 (40.69%), Query Frame = 2
Query: 10172 RLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESI---ISRIADDYPHALFYPFMLYVA--------------DVTSKSNFICKIGKILSNL--------KLVHQFYAAL------------LQMGQPEYYLQAWLD---EANDMFSSNSHDSNSRQN--IVNKYQDMYRKIIGNLDQL--------RKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGK-----------TMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFE--------ENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGK 11962
R+L+++ +H + D +++ W I L Q+ L P HI +++ IS+I PHA+ + + A D ++ C+ K+ +N+ K V QF A L + MG E+ ++ L N S H + S +N IV + Q + R+I LD+L K + +EEF F + + F+E S T + + +N I N + K + +D SP+LA +S + +PGQ + F ++ + I ++ + I+P+K PKK+ +G + + +FL K EDL D R+ Q + N ++ + A Y VIP+ GL++W++ + Y K T K+ E + S Y A+ S + S K+ E+ + DL+ + + +++ + + + A+ +LG+GDRHL N L++ G ++ ID+ F L IPE +PFRLT +M L PS + G F ++ +VL TL + ++ F+ + ++DW + + Q + S+ K K ++ L E L ++ +
Sbjct: 1460 RILELLVKHGDVLIDVINDGLNKTNVHIWKEI--LPQLFARLSHPSEHIRKTLVDLISKICTAAPHAVVFQVVSGAASSSTDGEELEEQQNDDRNRVRACCE--KLETNMSQSYPNLVKDVRQFVAELERINLLNEEKWSVVMGTMEHEMEKRLSLIRTENAKTESALHLTASVKNDIIVKRTQLLTRQIFDVLDELYQQTVIEPPKSKNEEEFVTAFAEVLTNAFQESRISRTTSPEKSWIPFKNLIANFVHRNSKKGMQTFETEDISPYLAS------------LSNSCVPMPGQ----ESVEF-DRVVSISRVARQVTILPTKTRPKKLGFVGSDGKQVAFLFKGREDLHLDERVMQFLRLCNVMLQPGKGKHRQSVAAYQAHHYAVIPLGPRSGLIKWVEGATPMFHIYRKWQMKEKALKQATKKNGETVPEIERPSNMYHNMI--RLAFADHKIDSSITSDRSKWPAEILEEVFESLTAKTPTDLISRELWMRANDATTWWSVTKRYSRSLAVMSMVGSVLGLGDRHLDNLLVDLKWGHVVHIDYNICFDKGK-NLRIPETVPFRLTRNMRHALGPSEMYGTFRESCVHVLSTLRSGHQVLTMLLDAFVFDPLVDWTSHEHTATSGVSLALQLAVYGSNWKTKAKERLTDAMELLNLRMSE 2101
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: atm-1 (Serine/threonine-protein kinase ATM [Source:UniProtKB/Swiss-Prot;Acc:Q9N3Q4]) HSP 1 Score: 87.8113 bits (216), Expect = 2.127e-16 Identity = 72/306 (23.53%), Postives = 137/306 (44.77%), Query Frame = 2
Query: 10904 PGQYNN---ITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRI-NFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGV-GGIFSQTLDNVLGTLGREQLTIMSIMHVFL 11806
PG Y+ IT + + + +F + GI PK I G + + Y + K +D+RQD +EQMF V N+++ K + ++TYNV+P+ G++E+ TV+L E + E ++++ +SE + ++ + + + Q F E + + + + F + +R +I N+ Q A Y++G+GDRH N L ++ + ID G + LP+PE +PFR+T +++ + G+ G ++ ++ L I+ + L
Sbjct: 2030 PGDYSTTDLITWKRWKD----VFTIADGIST------PKIWEIEGSDGKWYKTVWKK-DDVRQDVLVEQMFDVTNNMLEK-----------AMLRTYNVVPLDTECGVIEFCGGTVSLKEVMCGVTR--EGGLHREFNSEEVSA--SKVSSMMRQVQTESTETRRQVFVE---ICQQYSPVFRHFFYTNFSTAQIWRQKIINYRQSLATWSIVCYIVGLGDRHASNILFDQKLCTFVHIDLGMILEYSKRTLPVPEQVPFRITRDVLDPILIEGIENGQLAEECTQIMEKLKENGKVILGVASALL 2306
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: atm-1 (Serine/threonine-protein kinase ATM [Source:UniProtKB/Swiss-Prot;Acc:Q9N3Q4]) HSP 1 Score: 87.4261 bits (215), Expect = 2.345e-16 Identity = 72/306 (23.53%), Postives = 137/306 (44.77%), Query Frame = 2
Query: 10904 PGQYNN---ITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRI-NFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGV-GGIFSQTLDNVLGTLGREQLTIMSIMHVFL 11806
PG Y+ IT + + + +F + GI PK I G + + Y + K +D+RQD +EQMF V N+++ K + ++TYNV+P+ G++E+ TV+L E + E ++++ +SE + ++ + + + Q F E + + + + F + +R +I N+ Q A Y++G+GDRH N L ++ + ID G + LP+PE +PFR+T +++ + G+ G ++ ++ L I+ + L
Sbjct: 1353 PGDYSTTDLITWKRWKD----VFTIADGIST------PKIWEIEGSDGKWYKTVWKK-DDVRQDVLVEQMFDVTNNMLEK-----------AMLRTYNVVPLDTECGVIEFCGGTVSLKEVMCGVTR--EGGLHREFNSEEVSA--SKVSSMMRQVQTESTETRRQVFVE---ICQQYSPVFRHFFYTNFSTAQIWRQKIINYRQSLATWSIVCYIVGLGDRHASNILFDQKLCTFVHIDLGMILEYSKRTLPVPEQVPFRITRDVLDPILIEGIENGQLAEECTQIMEKLKENGKVILGVASALL 1629
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0080422) HSP 1 Score: 146.747 bits (369), Expect = 4.304e-34 Identity = 97/352 (27.56%), Postives = 180/352 (51.14%), Query Frame = 2
Query: 10778 KTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVIS-KDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+ W + F+ + P L Y P +++ KD L +PG YN ++ I+I ++ +Q++ SKQ P+K+ I G N + Y +L+K EDLRQD R+ Q+F+++N ++ D + + I+ Y VIP+S + GL+ W+ + TL + +D+ KKV Q + ++ ++ + FE DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT +++ ++ +G+ G + +T ++V+ L R + ++M+++ F+ + +L+W
Sbjct: 2020 RAWDIYYHVFQKISRQLPQLTSLEL--PYVSPKLMTCKDLELAVPGSYNP------GQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDD---PDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLI-RDYRDK-----KKVP---LNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLK-SPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW 2350
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Tor (gene:FBgn0021796 transcript:FBtr0336615) HSP 1 Score: 146.747 bits (369), Expect = 4.378e-34 Identity = 97/352 (27.56%), Postives = 180/352 (51.14%), Query Frame = 2
Query: 10778 KTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVIS-KDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+ W + F+ + P L Y P +++ KD L +PG YN ++ I+I ++ +Q++ SKQ P+K+ I G N + Y +L+K EDLRQD R+ Q+F+++N ++ D + + I+ Y VIP+S + GL+ W+ + TL + +D+ KKV Q + ++ ++ + FE DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT +++ ++ +G+ G + +T ++V+ L R + ++M+++ F+ + +L+W
Sbjct: 2021 RAWDIYYHVFQKISRQLPQLTSLEL--PYVSPKLMTCKDLELAVPGSYNP------GQELIRISIIKTNLQVITSKQRPRKLCIRGSNGKDYMYLLKGHEDLRQDERVMQLFSLVNTLLLDD---PDTFRRNLAIQRYAVIPLSTNSGLIGWVPHCDTLHTLI-RDYRDK-----KKVP---LNQEHRTMLNFAPDYDHLTLMQKVEVFEHALGQTQGDDLAKLLWLK-SPSSELWFERRNNYTRSLAVMSMVGYILGLGDRHPSNLMLDRMSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLIKAMEVTGIEGTYRRTCESVMLVLRRNKDSLMAVLEAFVYDPLLNW 2351
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: mei-41 (gene:FBgn0004367 transcript:FBtr0074271) HSP 1 Score: 127.487 bits (319), Expect = 2.724e-28 Identity = 102/355 (28.73%), Postives = 168/355 (47.32%), Query Frame = 2
Query: 10778 KTWKL-----KVSEFKNLKDFSPWLAKYNFRDSYYQP------DVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAA-YTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFL 11806
+T+KL ++S+ +FS L + + Y QP D S + +P N T FP + I I + + I+ S PKK+ I + + Y LVK +DLR+D R+ + ++ + +D + + I+TY V+P ++ GL+EW+ N L+ + M +Y + T+ + A +S E+ V T Q + + + LR+ F T S+Y R +I+ A+ Y+LG+GDRH +N L E GD + +DF F + LP PE++PFRLT +M+ + P GV G F + + L L +E T+MSI+ F+
Sbjct: 2115 RTYKLSDLDTRLSKLCKQPEFSQILLPF---EKYMQPTLPLNSDSNSSEGSHLPA--NQSTVNWFPYQQIYISGFQESVLILRSAAKPKKLTIRCSDGKDYDVLVKPKDDLRRDARLMEFNGLVKRYLHQD---APARQRRLHIRTYAVLPFNEECGLVEWLPN---LASYRSICMN-----LYAQRRLVMSTRQLQSLAVPLHESIERKREVFTKQLVPAHPPVFQEW--LRQRFAT----PHSWYEARNTYIRTVAVMSMVGYILGLGDRHGENILFAEGNGDAVHVDFNCLFNQGEL-LPYPEVVPFRLTHNMIVAMGPLGVEGSFRKCCEITLRLLKQESKTLMSILRPFV 2446
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0070972) HSP 1 Score: 127.487 bits (319), Expect = 3.180e-28 Identity = 88/313 (28.12%), Postives = 148/313 (47.28%), Query Frame = 2
Query: 10949 HIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMS--KDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY-----------KKVSSEFYTQYFPNTAAYT-------KSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+ I +E + ++P+K PKK+ G N Q Y+FL K EDL D RI Q ++ N IM+ D +A Y+VIP+ GL+ W+D + Y K + Q ++ + FY + P A + + W S ++ Q +E N L R+ + E +R F++ ++ Y++G+GDRHL N LIN +GDI+ ID+ F L IPE +PFRLT ++V+ + +G+ G F + VL + +E+ T+++++ F+ + ++DW
Sbjct: 1891 QVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAPGNGCYRA----HHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVAGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLL---QVLDELSQETPNDLLARELWCQAGNAAEWRQSVR-RFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRT-LRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDW 2194
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: nonC (gene:FBgn0263968 transcript:FBtr0343321) HSP 1 Score: 127.487 bits (319), Expect = 3.180e-28 Identity = 88/313 (28.12%), Postives = 148/313 (47.28%), Query Frame = 2
Query: 10949 HIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMS--KDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY-----------KKVSSEFYTQYFPNTAAYT-------KSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+ I +E + ++P+K PKK+ G N Q Y+FL K EDL D RI Q ++ N IM+ D +A Y+VIP+ GL+ W+D + Y K + Q ++ + FY + P A + + W S ++ Q +E N L R+ + E +R F++ ++ Y++G+GDRHL N LIN +GDI+ ID+ F L IPE +PFRLT ++V+ + +G+ G F + VL + +E+ T+++++ F+ + ++DW
Sbjct: 1891 QVYIESVESSVCVLPTKTKPKKVAFYGSNGQRYTFLFKGMEDLHLDERIMQFLSISNAIMACRSDAPGNGCYRA----HHYSVIPLGPQSGLISWVDGVTPVFALYKKWQQRRSQVAGNAGAGAVANVPRRFTDLFYNKLSPLLAKHNMQVSDPRRQWPISVLL---QVLDELSQETPNDLLARELWCQAGNAAEWRQSVR-RFVRCMSVMSMIGYVIGLGDRHLDNVLINLGSGDIVHIDYNVCFEKGRT-LRIPEKVPFRLTQNLVQAMGITGIEGPFRLGCEYVLKVMRKERETLLTLLEAFVYDPLVDW 2194
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-030131-9008]) HSP 1 Score: 365.54 bits (937), Expect = 3.400e-100 Identity = 232/747 (31.06%), Postives = 394/747 (52.74%), Query Frame = 2
Query: 9983 YSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRS----YVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVT--------SKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAA-------YTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWH--RMSRMSK-----QSIET-----FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
+S+ N + A + +++F D ++R+ E + ++S V+ L ++KL A+ KFPRLLQ++ + + D + S+P W+ I W+ QM+ LD P + V+ +I IA+ YP AL YP+M+ + T F+ K+ +L ++ F AL Q+ PE + W DE + + D K Q M +++G+ R G ++ +F + F +++ G+ +Y +++ + +++ +++ + E N+K++SPWL S ++ + + K+ LE+PGQY+ ++P PE H KI + +++M S + PK+III GD+E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ AL +TY VIPI+ +GL+EW++NT TL +F ++EQ + +EFY ++ A Y + ++K+ V T F + ++ + DLL+++F+ +S E+F LR +F +A+ +H++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT + ++P G+ + + L E +++ M VF+ LDW + ++ K +S+ T F +++N + RKL+ +P ++ EEL + + K +K + N ++ A+ Q L+ AT+ L R W G+EP
Sbjct: 3395 FSQQHVNTHGIVEAYMTMANFCDRRLRESEQKEEAISSKLQSLPEHVVKMMLKALKLSSEEARLKFPRLLQLVEVYPAETLDLMVREVV--SVPCWLLIGWISQMMALLDKPQATAVQHVIEEIAECYPQALIYPYMISSENYTFEESASGQRNREFVEKLESLLDKGGVIQGFVDALQQLSNPEMLFKDWWDEVKNQLDKPNLDKKKM-----KLQYMT-ELLGDAKSPRFGSYRRKFIQKFSKEVEKLLGAGGSKLYERRKDK--DFLQQVDRMVQSMRGFQKEPGNMKEYSPWL-------SSFKAETL-KNELEVPGQYDG-KSKPLPEYHAKITGFDERVKVMTSIRRPKRIIIRGDDERDYPFLVKGGEDLRQDQRIEQLFGVMNMILSQDTACSQRSLAL---RTYQVIPITSRIGLIEWMENTCTLKDFLSSRRTEQEQKTITR-PNEFYDEWISKVAGKVEGIRRYAELYKKAKRVDTVNNFRRIEQMVPD-DLLKRAFVRMSTTPEAFLSLRSHFSSSHAVLCISHWILGIGDRHLSNFMINTETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMRPLAESGLIQSVMVHSLRAFRAEPDLLLNTMDVFVKEPSLDWKNFELKQLKKGGTWTESVNTKEINWFPLQKVNFARRKLEGTNPSVITSEELCLGFEKMPEYKGLLAVARGEEQHNIRARLADKDLTVEDQVDCLLDQATDPNILGRVWIGWEP 4117 HSP 2 Score: 249.98 bits (637), Expect = 3.152e-65 Identity = 311/1344 (23.14%), Postives = 587/1344 (43.68%), Query Frame = 2
Query: 191 NIINRIHSYCLCEFNFPRLSSILKELFENEPKLLDIYSNN------ETKVYQIFIENFCDFIINLVKFAKEKLLPFCGLIKNYLMN------IVKSKKSSAKMKELSIKSLQDILTLTGNNNFEMN--IGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMDSGY-RFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKS--YAALSTRDFLQFWNAILQSNDDKDECSV----------------LIFDSFMKCAYKIIDQLDL----LYKSEDVNNEK-----INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKIC----NYNDELLITCLTLLVN-SPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLL----LFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLI-----RDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTW----SYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSE-NDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDL-SEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPP-SPVNAIFWMNTLEASVQSFCWL-LSMNLIDAYNYFT 3985
+II + C+ N L LF E LL + T +I E + + L F + G KNY + +V +K SAK + ++ L IL LT +++ N IG + + +L ++K TVL + EL+G + ++P+ + S L L+ ++ ++ K +++GC +G+ F K++ E +A I+ LK + + R+A + + L H + + IF + KH H N LK S+ T L+ +L+ Q+ A N + H + ++ +F ++ M S T+K L I+G G C V+ P++ + ++Y+ + + + YL E D++ LP + + IA +L+ L I P Y V+ RL V ++ P+ + R + + V S +V+Q +I CS PV +Q +S S + S ++ L++S + S++D+L+ + +L + KD V ++D+ ++ KI+++LDL + +++V ++ +++DP + PKDFI F+NL + N +W + L+ +S+ PLVSGFYK++ + I +FQ +C K + ++A F +L+ +++C Y DELL CL +++ P + ++ + P LQ A++LG + PL A LD LE W P ++ P Y +L + +S E D + ++ ++T S+ + L ++++++ + F + D + + + + R++R+LG +G +R L+ D + F + W+ E + + +PFKD+KP I L+ + ++ LAL+S+ Q K A E+LHSL+I ++GK A E+ K P +F + ++LA D+++V++ LF L+MQ+ +WF+ ++ +++ D + +DP + RD +G + F+K S K +K +K +RIY L + S +KRLGA FNS++ + + L+E +F ++ VE L+ ++K +GT+ Q + ++ + K+ ++++ R +P P+ + + + WLL + R ++L E + ++P + L + ++ E L P + A F ++ ++Q W+ L + +D YN FT
Sbjct: 36 DIIGDLGQECMITKNENELVLQTSLLFAKEEGLLSFLRRSLSTEKLGTTGVEILRETRVEIMNFLGAFLQRMSATVRGWEKNYAVELKDTCIVVYTKDKSAKCRNPALDLLIKILYLTKDSSITQNLRIGDMFNKFYGELCQKHKIPDTVLGCIYELLGVLGEVHPSEMVNNSDKLYKAYLGELKGQMTSTTKEPKLPVVAGCLKGIAALMVNFTKSVEEDPAASK--EIFDYALKAISPQTDIKRYAVIFAGLKLFAKHSSQFGSCLMDHYISIFDVMSKHCGHINAELKKSSYTALESFLK----QVATLVAEN-IELH-KSKLKFFMQKFCAIIRTMDS-----TNKELSIAIRGYGLFAAPCKVVCPQD-VDLMYTELIQRCKQMYLTESDRDDDNVYQLPSF-LDSIASVLVHLDRI---------------PEVYTPVLERLLVVQMDSFPQYSQRMQHATCRSIVKVFVAMAVRGPVLWSFTSSVVHQGLIRVCSKPV------LQSDERGVS----SGVSQSEDSTLVRSGKWKVPSSKDYLELFKGLLDCENLKDTGFVDGAPAAKNYNLRDLNRHLYDALVQSVMKIVEKLDLSVQKVSAADEVQSDASAGIVLSSDPTANLMPNKPKDFIAFINLVDFCSELLPSRNPEYFAQWMHPLCHELILQSIRFPLVSGFYKLLSLSMGIAKKTQYFQDVKQCPKQVGGSTM-ENACF----SLLAKFGKEVCVRMKQYKDELLAACLMFILSLHPGMVALDIKAYIP-------ALQAALRLGLSHAPLATAALDALESWSSFIP-----AAILQPHYTDILPHLDGYLKTTSSSEKDDSNMEVTFVSTG--SSKGYGQVL--LRLLKKSKRFS-----LGDESPIAAVRR---RVVRLLGHLGGQLNRSLVTAVSAEDMMKRF---VAWD--CEKRLSFAVPFKDMKPVIYLDSFLPRVTELALSSSDRQTKVAACELLHSLVIYMVGKGAQM---TEDDKSAPPMYNLHRKVFPVLLRLACDVDQVTRQLFEPLVMQLIHWFTNNRKFESQDTVAVLEAILDGI-------------VDPLDSTL-RDFSGTCIQEFVKWSI--KQTTPKQQEKSPANMKSLFKRIYSLALHPSVFKRLGAALAFNSMYRQFREESSLVEQFVFEVLVVFVESLALAHFDEKSVGTVQQCCSSLDHLKRIIKH-KADSLNINSKRRIPRGFPADQSVCLSNVVLWLLTQCGRPQTECRHKSMELFFEFVPLLPGNSSPAMWLDEQLKQRGPGFLISCLEGGGLLSQPTLREIEAPF---SIRGTLQ---WMDLLLAALDCYNTFT 1279 HSP 3 Score: 208.379 bits (529), Expect = 1.285e-52 Identity = 303/1384 (21.89%), Postives = 580/1384 (41.91%), Query Frame = 2
Query: 4805 QVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSD---LSLEEC--YLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYEN--IIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKIN---NFENPNERELQNVIVNLKIISTIYTSLG-------------PFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSW----AFNCFSSVVIATQSDEKFYTNLLLR----YNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLE---NILSRNVNS---NLMDSDSFLQHDGRCLM---IINIPYDIVNDHPCMDTFICLHHQMKNVGI---ISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMS---SINPFVESVLRLIIDWSSVPGVYDKVS-KANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNG---YLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSD--FVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFF-QLFVDLSSEKPDILFVNCFQSA---LLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSIN------------IPKQAKN--FDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIP-------YLMKLYK 8701
QVL W + P+ + P + + LL +++ IDS++C N N +F F LL+ ++ + K++ + + F + +E ++ + + +A +QSD +C Y++ I LQ+ L+ ++ + CR+ H E+ + Q + + +++ LL+ + + N ++ +++ + C Q L+ FF S I ++ ++ + E+ E ++ I K++ +Y+ L FC G E ELSK +L+ C + N ++ +R A+NC +++ + ++ KFY L N+ +F ++I V NFP E+ + ++ K+ + KE S + P++ S +++DSSL+ ++ + + + S + NS + + S S ++ L + + D +N H CM L M+ I + E SD+P WMK ++I+ FI KLIIN IF+PYA W+ L++ ++ + I+ V ++ ++ W+SV + +N L+ +L +NC+ ++ R N+E+ +++ WK+ + IPY I++ + N G+++L V+ N Y G +D F + + + K V+ A E+ G++L + + +++ E L IT+T L + + D F+ CL+ + K+ ++ R I+ + +L L LE C + ++ E+F L + + + +K + + H+ + + + + A V F S P E+ L + Q S + D V A LL G D + + +RNF S LP ETLER +L+ L+ S+ I +FL++AT+++LEMTSH PDF + +F+ L S F++ T + L P F+ Q + + Q V I P + ++W+ +S ++ ++ + S+ P F + + + + + + ++E + + + + + KE ++ F +K + Q+ +++ K +++ V LYR+Y G LP+I+IQ S IAPLQ LAQ + +K LF L+ G+L E E + + L Q + L + IS ++ + + + + PS V S + + +LLE+ L+ +S E PP K+ + G +P +L KLY+
Sbjct: 1631 QVL-KGWDLLRPW-WDGPAATPESKTSVLSLLAKVLQIDSSVCSNTSHPAFNAVFTTFTALLTDVSMPLNLKSQALIMLPFFTALPSMP-------LEELRRALE-SLVATHFPMQSDEFPRGSLQCNNYMDCIRKFLEALQL-----SQSPLLLKLMARVLCRDKKHIMEELFQACFQKIAHQSYLGKQVLLLSSTYQSFQAKEVPSNFMLMGLIDRVLLPLASHCSPQALSQFFISNIADIMTTLQTRFTKSVESVFESQIMMKIGCCKLLEVLYSRLPKEEVYSKNSAINQAFCG---TGCAEG---NELSK--NLLKSCFEAFTENMTGEMVLLELRRQFHCAAYNCAIALISCSFNETKFYQGFLFTEKPDKNQFIFDNLIDSQRVYNFPIEIDVPIERKKKYVMIRKE---------VSGENGDAPVYLSSQSYMADSSLSEEMSQFDFSTGVQSFSYNSQNPSGVSSSSRMRERKEVLSQDETVELEMDELNQHECMANMTALLRHMQRNNITPKVEEGVRPSDLPPWMKFLQGKLDNPSTPLNIRLFIAKLIINTEEIFRPYAKHWLGPLMQLVVSSSNGGEGIHFMVVDIVVTVLSWASVASPKGNTRDEVLVNRLLGFLFKNCFHSKRAVFRHNLEIIRTVVECWKDCLTIPYDLIYERFAGTDPNSKDNSVGIQLLGIVMANNLPPYDAACGIEHDRYFQSLANNLSFIR--YKEVYSAAAEVIGLIL-NYMTERENQIEGTL---FNITVTKLMDLRKKEVDDKFIVCLSKVSKHFPPLVDRFINPVFYLLPKLHGMLKTHCLE---CVLSRADVIPEIFLHLKTKGLSQIMSHKDEGRQRVCLDIIHKILACLKPEELKEILGA--VTAFASH-PSPVCRERMYDILMWIQDNYSDSESREDSTSVEVLSVARETLLQGLTDENYGLQLYVRNFWSHESRLPPETLERMLVVLKSLY--SSRI--------EEQFLSLATDLLLEMTSHSPDFTRNMFEFPL-SECKFQDYTIDSNWRMRSTVLTPMFMET-QATQGAEAAGSQAATVRGQIRATQTSLEFSQTLAPGAGRRSAYNWLTGSSVDTLADYSLSSDSLSSLLVFDKKRSERPQAAWR---AVGAGFGSKRLTATSDDTDSRTAAERERRADILRLRRRFLKD--KEKESIKFAKKEIHSQRTERERRADLKIRQDAQVTLYRSYRVGDLPDIQIQFSSLIAPLQALAQRDATLAKQLFSSLFAGVLVEMERLKSNKETADILKELVQTLNAFLNKSTVYFPPFISCIQDMSYHHKALLGVEPSLVSATCLASLQQPMGILLLEESLLHGAGAS-----EEPPLKRAR------GKRELPPDTERWIHLAKLYR 2942
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: AL844179.1 (pep chromosome:GRCz11:CHR_ALT_CTG8_1_27:46082265:46126761:-1 gene:ENSDARG00000112020.1 transcript:ENSDART00000184694.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:AL844179.1) HSP 1 Score: 158.303 bits (399), Expect = 1.686e-38 Identity = 140/561 (24.96%), Postives = 262/561 (46.70%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAW---LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSK-LFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHI-KIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ LV Q ++ + + + W L+EA+ ++ + + + + ++ + L++ F + + + L EA +D Y + N + + + W L F+ + P L + Y P ++ +D L +PG Y+ P + I +I + P +Q++ SKQ P+K+ I+G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ T EK +V FE N + DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 120 IDTWLQV--IPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFG----ERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEA-------QDWCRKYMRSGN--------VKDLTQAWDLYYHVFRRISKQLPQLTSLELQ--YVSPKLLMCRDLELAVPGTYD-------PNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLAND---PASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDYDHLTL-MEKVEV------FEHAVNNTAGDDLAKLLWLK-SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTR 633
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 157.918 bits (398), Expect = 2.050e-37 Identity = 140/561 (24.96%), Postives = 262/561 (46.70%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAW---LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSK-LFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHI-KIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ LV Q ++ + + + W L+EA+ ++ + + + + ++ + L++ F + + + L EA +D Y + N + + + W L F+ + P L + Y P ++ +D L +PG Y+ P + I +I + P +Q++ SKQ P+K+ I+G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ T EK +V FE N + DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 1898 IDTWLQV--IPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGE----RNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEA-------QDWCRKYMRSGN--------VKDLTQAWDLYYHVFRRISKQLPQLTSLELQ--YVSPKLLMCRDLELAVPGTYD-------PNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLAND---PASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDYDHLTL-MEKVEV------FEHAVNNTAGDDLAKLLWLK-SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTR 2411
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 153.68 bits (387), Expect = 4.098e-36 Identity = 142/582 (24.40%), Postives = 266/582 (45.70%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAW---LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSK-LFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHI-KIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKD-YQLTKSLKALS--------------------FIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ LV Q ++ + + + W L+EA+ ++ + + + + ++ + L++ F + + + L EA +D Y + N + + + W L F+ + P L + Y P ++ +D L +PG Y+ P + I +I + P +Q++ SKQ P+K+ I+G N + FL+K EDLRQD R+ Q+F ++N +++ D L K+L+ +S I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ T EK +V FE N + DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 1898 IDTWLQV--IPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGE----RNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEA-------QDWCRKYMRSGN--------VKDLTQAWDLYYHVFRRISKQLPQLTSLELQ--YVSPKLLMCRDLELAVPGTYD-------PNQSIIRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLANDPASLRKNLRQVSCVHVSEHCRISDVLISLQHIIIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDYDHLTL-MEKVEV------FEHAVNNTAGDDLAKLLWLK-SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTR 2435
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458]) HSP 1 Score: 137.117 bits (344), Expect = 4.810e-31 Identity = 98/387 (25.32%), Postives = 183/387 (47.29%), Query Frame = 2
Query: 10937 FPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWE-KSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL 12094
FP + + + ++I+ S Q PKKI + G + + Y+ + K +DLR+D R+ + ++N + KD +S + I+TY VIP+++ G++EW++ T L K K++ Y+ +E P TA + + + DV+ + + F+ S+Y R + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PE++PFRLT +MV + P G G+F Q + +L + ++ +MS++ FL + +++W + ++ F++ ++N S L + +L E +++ N K M S + L+ AT+ L + G+ P L
Sbjct: 2277 FPGHWVYLSGFDDTVEILASLQKPKKISLKGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKSLRKD---AESRRRDLRIRTYAVIPLNEECGIIEWVNKTAGLRHILTKLYKEKGIYVS---GTELKKLILPKTAPFQEKLKLHKDVLCARHP-----------PVFHEWFLRTFPDPTSWYNSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETF-DVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVILRLMRDQREPLMSVLKTFLHDPLVEWSK-------PVKGFSKTQVNESGEILNEKAKTHVLDIEQRLQGVIKNRNKVMGLPLSIEG---HVHYLIQEATDDNLLCMMYLGWGPYL 2635
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:100488663]) HSP 1 Score: 396.741 bits (1018), Expect = 2.046e-109 Identity = 246/778 (31.62%), Postives = 405/778 (52.06%), Query Frame = 2
Query: 9935 GLLNKSFYCFNKIISMYSESDGNK-------KELSAALVVVSDFYDAQIRQFEN--------DGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML------YVADVTSKSN--FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKI---IGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFY--------TQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHR------------MSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKY-GKSNWFKCMKNFQSEDA-------------ETSQTKKLVSMATNSGFLARTWQGFEP 12088
GL KS + F + +E + + + + A + + DF D+ +R+ E D P+++ VE + ++KL A+ KFPR+LQII Q+ + D + +IP W +I W+ QM+ LD S V+ II IA++YP AL YPFM+ + V N F+ +I L + F AL Q+ P Q W +E ++ S S + N + +++Y+++ +GN+ G F+ FS+ + + F DG+ + ++ +QFS+ + ++++ + K E NLK++SPW+ S ++P+ + ++ LEIPGQY+ ++P PE H+KI + +++M S + PK+II+ G++E+ Y FLVK GEDLRQD RIEQ+F +MN I+S+D ++ L KTY VIP++ +GL+EW++NT TL EF TM ++E +Y + + + + ++ K D ST F E + L+ DLLR++F+ +S E+F LR +F + +A+ +H++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT +V + P GIF + + L + +++ M VF+ LDW M + S+ + ++I+ + RKL +P + EEL++ + G + + + + A E +Q + L+ AT+ L R W+G+EP
Sbjct: 3350 GLYRKSLHYFMNAVRKATEEEQSHSIDKVDVRGIIKAYMTLVDFCDSHLRKVEEKSAVMDHADYQHFPEIM---VEKMIKALKLNSSEARLKFPRMLQIIEQYPSETLDL--MAREICTIPCWQFIGWISQMMAMLDKKESIAVQHIIEEIAENYPQALVYPFMVSGENYNFEDTVVGHKNKEFVDRIKSKLDKDNVAQDFIHALEQLSNPPMIFQDWKEEVSNELSKASVNRN-------RVKELYKELCATLGNVKDPFMGAFRRRFSEKYTKEFDKAFGPDGSKLLSMKSDQFSKSAEPLMVKMRSEQQK--EPGNLKEYSPWM-------SGFKPEFL-RNELEIPGQYSG-RSKPMPEYHVKISGFDERVKVMASIRKPKRIIVRGNDEREYPFLVKGGEDLRQDQRIEQLFEIMNIILSQDAACSQRHMQL---KTYQVIPMTARIGLIEWMENTCTLKEFILNTMTEDEAKVYNSKNGPLMHYNVWLDKREKIGDPRQHVTAYTKCDRTSTVASFREREALVPK-DLLRRAFVKMSTTPEAFLSLRSHFARSHALLCISHWILGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLPVPELMPFRLTRQIVNLMLPMKESGIFDSVMVHSLRAYRSDPGLLITTMDVFIKEPSLDWKNLELKQIKKKGEWMKDVDTTSLNWYPAQKIHCAKRKLAGANPCEITCEELRLGHEGSPTYLAFLAVARGDKAHNKRANDPKDGLSEEAQVQCLIDQATDPNILGRVWKGWEP 4100 HSP 2 Score: 216.853 bits (551), Expect = 4.800e-55 Identity = 267/1093 (24.43%), Postives = 468/1093 (42.82%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNI------VKSKKSSAKMKELSIKSLQDILTLTGNNN--FEMNIGVCLSDLFSQLQNKS--STTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEI----NNSKTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMD-SGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINY-LVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTL--LLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTI--LKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIF 3448
E F D + +KF L ++ Y M+I V +K +AK K +++ L + L N+ E IG + + +L KS S TVL + EL+G + + P T S L L+ ++ N K +I+GC +GL F K + E K+ I+ +K + R+A + L+ L H + + + Q +F I K H N +K A LD +L+ I + ANN + + ++ QF ++KM ++K L I+G G C + K+ + ++Y + + + YL E D E+ +Y + + L S+ ++ + P Y ++ RL + I+ P+ Y + + +L V S+I +V+Q +I CS P+ I QD L E + E K + + +D+L + +L+ + KD + L++D +K K+I++LDL + +D E +DP + PKDF FVNL + + + + W + Y LV +S LPLVSGFYK++ ++K + +F+ N + K A D L A+F + S KI + DELL +CLT +++ P I + + + + LQ+A +LG PL LD L+ W P ++ P Y+ + LL +++ D + L A R SR L + +I+Q + + + + + +SL + NR++RILG +G +R L+ S +++W+ E + +++PF DIKP I L+ + ++ LAL+++ Q K A E+LHS++ +LGK A K+ + + F + ++LA D++KV+ L+ L+M + +WF+ ++ +++ + +DP + RD GQ + FL+ S + VN +R+Y L + + +KRLGA FN+I+
Sbjct: 98 EEFKDCREDALKFLSTFLEKIGSNVQPYAMDIKTLCVTVYTKDRAAKCKIPALELLIKLFQLLKNSYKIEEFKIGEIFNKFYGELATKSKLSDTVLEKVYELLGILGEVQPCEMTDNSEKLFKAFLGELKAQMISSTRNPKFPVIAGCLKGLSALMINFTKTMEE--DPKTSKEIFDYTVKAISPQVEMKRYAVPLAGLNLLALHASQFSNYLMDNYQSLFEVISKWCGHTNGEIKKLAFAALDSFLKQIAHLV----ANN--AEAHKNKLQFFMEQFYKVIRKMDC-----SNKELSIAIRGYGLFAAPCKAVNAKD-VDLMYIELIQRCKQMYLTEADTEED-------NVYQLPNFLQSVASVI--------LRMDSIPEVYTPILERLLVLQIDSFPQYSLKMQYSCSKSVLKVFLSLAGKGPVLWSLISTVVHQGLIRVCSKPI----DIAQD-GLGKEGSEAEAAAATGEVRAGK-WKVPTYKDYLDLFRNLLRCDQLKDSIFSDEIFSTLNSPLQSLNRLLYDELVKSILKVIEKLDLSLQKQDSGQENDGGINSSLIIATSDPAANLYPNKPKDFTAFVNLVEFCSEILPKEHIEYFESWV-YAFGYELVLQSTRLPLVSGFYKLLSVVMKNVKKIRYFEGFNSKTYKKAPEDPERLSCFALFAKFGKEVSS---KIRQFKDELLASCLTFVLHLPHDIIMMDIKAY------IPALQIAFKLGLSCPPLADVGLDALQDWSTYIPS-----DILQPYYKDIIPLLDGYLTNLSSTDESLSDLD----AVRISRALQKGFNK-HLIQQLKRTKTLS--VKEESSL---AAVSNRVVRILGSLGGQINRSLVTATSTEEMIKCHVSWDT--EKRLTFDVPFMDIKPVIYLDTFLPRVTELALSASDRQTKVAACELLHSIVAFMLGKAAQMPDDKKMGSSPMYKLYKRTFPVLLRLACDVDKVTMQLYKPLVMSLIHWFTNNKKFESQDTVALLEAILAGI-------------VDPVDSTL-RDFCGQCIQEFLRWSIKQTTPEQQAKSPVN--TTSLFKRLYSLALHPNAFKRLGAALAFNNIY 1112 HSP 3 Score: 110.153 bits (274), Expect = 9.305e-23 Identity = 158/733 (21.56%), Postives = 304/733 (41.47%), Query Frame = 2
Query: 4799 IVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLA----LFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGP--FCNQ--DKVGLREKKLIGELSKICSLILYCKSDDSTNKLI-YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNS-NLMDSDSFLQH----------DGRCLM-IINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSS---DVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSS---VPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGY-LFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQI 6856
+V + NW ++D S++ + + + + LL +++ IDS++C + +F + ++L+ L + K++ I + F K G ++ + F NF + Y++ I L++ ++ ++ I CR+ H E+ + + + + ER + ++ LL +F E ++ + N+ ++ C L FF + I ++ +K + F +E +N I K++ +Y+ L C++ + + EL+K +LI C + N Q++ R + A+NC S++ S+ KFY L K P E ++ K++ + KE +S +Y S +++DSSL+ ++ + + S V S + D L +G+ ++ D +N H CM L M + I +V + D+P WMK H ++I+ FI KLI+N +F PYA FW+ +++ ++ S I+ V L I+ WS+ +P + +SK I N L+ +L +N + + ++ R N+E+ ++L WKE + IPY I++ + N G+++L VL N + F D + F + + K V+ A E+ G++L I
Sbjct: 1655 LVNAVLQNWKRLD--SWWCKDSSPESKMAVLTLLAKVLQIDSSVCFDINHLAFAEVFRTYTSILTDQTLGLNLKSQAIIILPFFTKLTG---GKLTELKNTLDLFVASNFPMKCDEFPRGTLKFNNYVDCIKKFLDALEL-----SQSPMLLQLMTEILCRDERHFMEELFQSSFKKVIERSSCDAQVILLNTLHNMFTSESVMLNG--TLQSLTNRCLLTLLWNCSGDALLVFFTNIICLAMDTLK-SRFTKVSEAAFENQITKKWGYYKMLEVLYSRLSKDDICSKVNNAYHVSSNPEGNELTK--ALIKLCYDTFTENMCGETQLLEKRRQYHCAAYNCAISLISCVFSELKFYQGFLFTEKKE------------KVPME------RKKKYFAIRKEARDASSADSDEPRY-----LSSQSYMADSSLSEEMSQFD--FSTGVQSFSYSSQDKMLSQSASRKKELITEGKTFDDVMEFEMDELNQHECMAAMTGLIKHMNSSEITPKVEEGASPQDLPPWMKFLHGKLGNTSTPLNIRLFIAKLIVNTEEVFCPYAKFWIGPMLQLIVSGNNGGSGIHYMVIETLVTILSWSTAIRLPLFHIHISKEEILANRLLEFLMKNVFHEKRAVYRHNLEIIKTVLECWKECLSIPYMLIYEGFSGTDPNTKDNSVGIQLLGLVLANNFSPFDQKCGIDAERYFQCLANNLALTRFKEVYIAAAEVIGLVLHYI 2347 HSP 4 Score: 103.605 bits (257), Expect = 9.243e-21 Identity = 117/447 (26.17%), Postives = 200/447 (44.74%), Query Frame = 2
Query: 7388 QSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFV------NMPQELRSYSMSHD-----------QKFKVPTSINIPKQAKNFDWIQLAS--TLQFPSQEINEN--------NYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSA-VYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLK 8644
+ LL G +D + ++ +RNF S LP+ T ER IL L+ S I +L++ATN++LEMTS PD+++ +F+ H S F++ T + L P FV +M + +M D Q F+ + NI ++ +F+W+ +S TL S E E+ N ++E + P + + +QK L + ++ ++ S + F + + Y ++ + REKA++ IE+ +K A + LYRNY G+LP+I+I + IAPLQ LAQ + +K LF L++G+L E + L +QF++ L I+ + + ++LNP+ V + S + L +LLEK L+ H+ + + PPAKK++
Sbjct: 2481 KEGLLQGLVDDNSELQLIVRNFWSDETRLPSNTTERMLAILSSLY--STKI--------EKHYLSLATNLLLEMTSKSPDYLRKMFE-HPLSECKFQDYTIDSSWRLRSTVLTPMFVETQLSQSMQRSRMQGTMEADEPEGGQLRATQQHFQFTPTQNIGGRS-SFNWLTGSSMDTLADYSVESPESLPSALLFVNKRNE-----KVRRGPLKPLGPNFGTQKLGLPGHVTESKTKSIEERSEILRLRRRFLKDREKLSLIYARKGTAEQKREKAIK----------IEQKLKQDAQITLYRNYRHGELPDIQIAYSNLIAPLQALAQRDPTMAKLLFSSLFSGILSE------TASNASLIGKLLEQFNSFLSNSLSYFPPFIACVQDMCYQHDELLHLNPANVSTSCLASLQQPLGILLLEKGLL-HI-----EIPDEPPAKKMR 2888
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:100488663]) HSP 1 Score: 394.43 bits (1012), Expect = 1.010e-108 Identity = 246/770 (31.95%), Postives = 400/770 (51.95%), Query Frame = 2
Query: 9935 GLLNKSFYCFNKIISMYSESDGNK-------KELSAALVVVSDFYDAQIRQFEN--------DGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML------YVADVTSKSN--FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKI---IGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHR------------MSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKY-GKSNWFKCMKNFQSEDA-------------ETSQTKKLVSMATNSGFLARTWQGFEP 12088
GL KS + F + +E + + + + A + + DF D+ +R+ E D P+++ VE + ++KL A+ KFPR+LQII Q+ + D + +IP W +I W+ QM+ LD S V+ II IA++YP AL YPFM+ + V N F+ +I L + F AL Q+ P Q W +E ++ S S + N + +++Y+++ +GN+ G F+ FS+ + + F DG+ + ++ +QFS+ + ++++ + K E NLK++SPW+ S ++P+ + ++ LEIPGQY+ ++P PE H+KI + +++M S + PK+II+ G++E+ Y FLVK GEDLRQD RIEQ+F +MN I+S+D ++ L KTY VIP++ +GL+EW++NT TL EF TM ++E +Y + K D ST F E + L+ DLLR++F+ +S E+F LR +F + +A+ +H++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT +V + P GIF + + L + +++ M VF+ LDW M + S+ + ++I+ + RKL +P + EEL++ + G + + + + A E +Q + L+ AT+ L R W+G+EP
Sbjct: 3347 GLYRKSLHYFMNAVRKATEEEQSHSIDKVDVRGIIKAYMTLVDFCDSHLRKVEEKSAVMDHADYQHFPEIM---VEKMIKALKLNSSEARLKFPRMLQIIEQYPSETLDL--MAREICTIPCWQFIGWISQMMAMLDKKESIAVQHIIEEIAENYPQALVYPFMVSGENYNFEDTVVGHKNKEFVDRIKSKLDKDNVAQDFIHALEQLSNPPMIFQDWKEEVSNELSKASVNRN-------RVKELYKELCATLGNVKDPFMGAFRRRFSEKYTKEFDKAFGPDGSKLLSMKSDQFSKSAEPLMVKMRSEQQK--EPGNLKEYSPWM-------SGFKPEFL-RNELEIPGQYSG-RSKPMPEYHVKISGFDERVKVMASIRKPKRIIVRGNDEREYPFLVKGGEDLRQDQRIEQLFEIMNIILSQDAACSQRHMQL---KTYQVIPMTARIGLIEWMENTCTLKEFILNTMTEDEAKVYNR---------------------KCDRTSTVASFREREALVPK-DLLRRAFVKMSTTPEAFLSLRSHFARSHALLCISHWILGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLPVPELMPFRLTRQIVNLMLPMKESGIFDSVMVHSLRAYRSDPGLLITTMDVFIKEPSLDWKNLELKQIKKKGEWMKDVDTTSLNWYPAQKIHCAKRKLAGANPCEITCEELRLGHEGSPTYLAFLAVARGDKAHNKRANDPKDGLSEEAQVQCLIDQATDPNILGRVWKGWEP 4068 HSP 2 Score: 196.052 bits (497), Expect = 1.049e-48 Identity = 300/1361 (22.04%), Postives = 568/1361 (41.73%), Query Frame = 2
Query: 4799 IVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLA----LFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGP--FCNQ--DKVGLREKKLIGELSKICSLILYCKSDDSTNKLI-YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP----LFRHIIYKDYVINFPSELLIFKMKQ-TKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNS-NLMDSDSFLQHDGRCLM--IINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSS---DVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGY-LFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNI-PEWKND--SQINANVVKCFESCLPCSTQDEKKVRSLFFQLF-----VDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFV--NMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKD-----------EYSMEWSSSQIPGVDMSLSIKSQKSFL--------NLSTSVMHIEN---EDKASNQQENQTEFQTINKTIETN-------YTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSA-VYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLK 8644
+V + NW ++D S++ + + + + LL +++ IDS++C + +F + ++L+ L + K++ I + F K G ++ + F NF + Y++ I L++ ++ ++ I CR+ H E+ + + + + ER + ++ LL +F E ++ + N+ ++ C L FF + I ++ +K + F +E +N I K++ +Y+ L C++ + + EL+K +LI C + N Q++ R + A+NC S++ S+ KFY L K +F ++I FP E+ + K K TK + F Y +D+ EP + S +++DSSL+ ++ + + S V S + D L R ++ D +N H CM L M + I +V + D+P WMK H ++I+ FI KLI+N +F PYA FW+ +++ ++ S I+ V L I+ WS+ + N L+ +L +N + + ++ R N+E+ ++L WKE + IPY I++ + N G+++L VL N + F D + F + + K V+ A E+ G++L I + + + KE+ S + F+ CL + KN R ++ ++ +L L + LEL+ M + + +LF +L + + + + + ++ ++ + P ++ S I A F C +++ +F ++ + S+ + + + LL G +D + ++ +RNF S LP+ T ER IL L+ S I +L++ATN++LEMTS PD+++ +F+ H S F++ T + L P FV + Q ++ M + P + ++F + P+Q I + + +YS+E S +P + ++ +++K N T + + E K E ++E + + + Y ++ + REKA++ IE+ +K A + LYRNY G+LP+I+I + IAPLQ LAQ + +K LF L++G+L E + L +QF++ L I+ + + ++LNP+ V + S + L +LLEK L+ H+ + + PPAKK++
Sbjct: 1613 LVNAVLQNWKRLD--SWWCKDSSPESKMAVLTLLAKVLQIDSSVCFDINHLAFAEVFRTYTSILTDQTLGLNLKSQAIIILPFFTKLTG---GKLTELKNTLDLFVASNFPMKCDEFPRGTLKFNNYVDCIKKFLDALEL-----SQSPMLLQLMTEILCRDERHFMEELFQSSFKKVIERSSCDAQVILLNTLHNMFTSESVMLNG--TLQSLTNRCLLTLLWNCSGDALLVFFTNIICLAMDTLK-SRFTKVSEAAFENQITKKWGYYKMLEVLYSRLSKDDICSKVNNAYHVSSNPEGNELTK--ALIKLCYDTFTENMCGETQLLEKRRQYHCAAYNCAISLISCVFSELKFYQGFLFTEKKEKNLLIFENLIDLQRSYTFPIEVEVSKKKNLTKAFLFIS----FLFTIYLNDE--DEPRYLSSQSYMADSSLSEEMSQFD--FSTGVQSFSYSSQDKMLSQSARKTFDDVMEFEMDELNQHECMAAMTGLIKHMNSSEITPKVEEGASPQDLPPWMKFLHGKLGNTSTPLNIRLFIAKLIVNTEEVFCPYAKFWIGPMLQLIVSGNNGGSGIHYMVIETLVTILSWSTKEEIL-------ANRLLEFLMKNVFHEKRAVYRHNLEIIKTVLECWKECLSIPYMLIYEGFSGTDPNTKDNSVGIQLLGLVLANNFSPFDQKCGIDAERYFQCLANNLALTRFKEVYIAAAEVIGLVLHYIYHNEKVNAPIFDYVVKELK---RHQTSNKEDKFIMCLNKVVKNFPPFADRFMTVVLYLLPKLHGVLKTQCLELI---MHRAEDIPDLFIELKNKEFCQIMNSRDDERQKVCLDIIYKILSKLKPAELHEFMSSIAAFNSHSFPVC-------RERMYEIFMWIYDNYRDQESQSDSKSVEVFSMAKEGLLQGLVDDNSELQLIVRNFWSDETRLPSNTTERMLAILSSLY--STKI--------EKHYLSLATNLLLEMTSKSPDYLRKMFE-HPLSECKFQDYTIDSSWRLRSTVLTPMFVETQLSQSMQRSRMQGTMEADEPEGGQLRATQQHFQFT--------PTQNIGGRSSFNWLTGSSMDTLADYSVE-SPESLPSALLFVNKRNEKVRRGPLKPLGPNFGTQKLGLPGHVTESKTKKGIEERSEILRLRRRFLKDREKLSLIYARKGTAEQKREKAIK----------IEQKLKQDAQITLYRNYRHGELPDIQIAYSNLIAPLQALAQRDPTMAKLLFSSLFSGILSE------TASNASLIGKLLEQFNSFLSNSLSYFPPFIACVQDMCYQHDELLHLNPANVSTSCLASLQQPLGILLLEKGLL-HI-----EIPDEPPAKKMR 2888 HSP 3 Score: 192.2 bits (487), Expect = 1.639e-47 Identity = 265/1124 (23.58%), Postives = 462/1124 (41.10%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNI------VKSKKSSAKMKELSIKSLQDILTLTGNNN--FEMNIGVCLSDLFSQLQNKS--STTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEI----NNSKTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK-----INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINY-LVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDN--NSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTI--LKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIF----------PILKNDILLMENEIFAMMYYLVECQRLSE 3535
E F D + +KF L ++ Y M+I V +K +AK K +++ L + L N+ E IG + + +L KS S TVL + EL+G + + P T S L L+ ++ N K +I+GC +GL F K + E K+ I+ Y A+ + L+ L H + + + Q +F I K H N +K A LD +L+ I + ANN + + ++ QF ++KM ++K L I+G G C + K+ + ++Y + + + YL E D E+ +Y + + L S+ ++ + S P Y ++ RL + I+ P+ Y + + +L V S+I +V+Q +I CS P+ I QD L E + E K + + +D+L + +L+ + KD + L++D +K K+I++LDL + +D E +DP + PKDF FVNL + + + + W + Y LV +S LPLVSGFYK++ ++K + +F+ N + K A D L A+F + S KI + DELL +CLT +++ P I + + + + LQ+A +LG PL LD L+ W P ++ P Y+ ++ P+ Y N L+ T S+ ++ R +A++ N + L + + L L +L ++ +++W+ E + +++PF DIKP I L+ + ++ LAL+++ Q K A E+LHS++ +LGK A K+ + + F + ++LA D++KV+ L+ L+M + +WF+ ++ +++ + +DP + RD GQ + FL+ S + VN +R+Y L + + +KRLGA FN+I+ PI N N IF + CQ +
Sbjct: 68 EEFKDCREDALKFLSTFLEKIGSNVQPYAMDIKTLCVTVYTKDRAAKCKIPALELLIKLFQLLKNSYKIEEFKIGEIFNKFYGELATKSKLSDTVLEKVYELLGILGEVQPCEMTDNSEKLFKAFLGELKAQMISSTRNPKFPVIAGCLKGLSALMINFTKTMEE--DPKTSKEIF-----------DYTVKAI-TGLNLLALHASQFSNYLMDNYQSLFEVISKWCGHTNGEIKKLAFAALDSFLKQIAHLV----ANN--AEAHKNKLQFFMEQFYKVIRKMDC-----SNKELSIAIRGYGLFAAPCKAVNAKD-VDLMYIELIQRCKQMYLTEADTEED-------NVYQLPNFLQSVASVILRMDS--------IPEVYTPILERLLVLQIDSFPQYSLKMQYSCSKSVLKVFLSLAGKGPVLWSLISTVVHQGLIRVCSKPI----DIAQD-GLGKEGSEAEAAAATGEVRAGK-WKVPTYKDYLDLFRNLLRCDQLKDSIFSDEIFSTLNSPLQSLNRLLYDELVKSILKVIEKLDLSLQKQDSGQEVSSLIIATSDPAANLYPNKPKDFTAFVNLVEFCSEILPKEHIEYFESWV-YAFGYELVLQSTRLPLVSGFYKLLSVVMKNVKKIRYFEGFNSKTYKKAPEDPERLSCFALFAKFGKEVSS---KIRQFKDELLASCLTFVLHLPHDIIMMDIKAY------IPALQIAFKLGLSCPPLADVGLDALQDWSTYIPS-----DILQPYYKDII---PLLDG--YLTN----------------LSSTDESLSDLDAVRISRALQKGFNKHLIQQLKRTKTLSVVLYFVL---------FIATSTEEMIKCHVSWDT--EKRLTFDVPFMDIKPVIYLDTFLPRVTELALSASDRQTKVAACELLHSIVAFMLGKAAQMPDDKKMGSSPMYKLYKRTFPVLLRLACDVDKVTMQLYKPLVMSLIHWFTNNKKFESQDTVALLEAILAGI-------------VDPVDSTL-RDFCGQCIQEFLRWSIKQTTPEQQAKSPVN--TTSLFKRLYSLALHPNAFKRLGAALAFNNIYREFREMAEKKPIPHNFFAYHYNSIFISCFMPSICQSFGQ 1081
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:100488663]) HSP 1 Score: 394.43 bits (1012), Expect = 1.039e-108 Identity = 246/770 (31.95%), Postives = 400/770 (51.95%), Query Frame = 2
Query: 9935 GLLNKSFYCFNKIISMYSESDGNK-------KELSAALVVVSDFYDAQIRQFEN--------DGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML------YVADVTSKSN--FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKI---IGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHR------------MSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKY-GKSNWFKCMKNFQSEDA-------------ETSQTKKLVSMATNSGFLARTWQGFEP 12088
GL KS + F + +E + + + + A + + DF D+ +R+ E D P+++ VE + ++KL A+ KFPR+LQII Q+ + D + +IP W +I W+ QM+ LD S V+ II IA++YP AL YPFM+ + V N F+ +I L + F AL Q+ P Q W +E ++ S S + N + +++Y+++ +GN+ G F+ FS+ + + F DG+ + ++ +QFS+ + ++++ + K E NLK++SPW+ S ++P+ + ++ LEIPGQY+ ++P PE H+KI + +++M S + PK+II+ G++E+ Y FLVK GEDLRQD RIEQ+F +MN I+S+D ++ L KTY VIP++ +GL+EW++NT TL EF TM ++E +Y + K D ST F E + L+ DLLR++F+ +S E+F LR +F + +A+ +H++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT +V + P GIF + + L + +++ M VF+ LDW M + S+ + ++I+ + RKL +P + EEL++ + G + + + + A E +Q + L+ AT+ L R W+G+EP
Sbjct: 3285 GLYRKSLHYFMNAVRKATEEEQSHSIDKVDVRGIIKAYMTLVDFCDSHLRKVEEKSAVMDHADYQHFPEIM---VEKMIKALKLNSSEARLKFPRMLQIIEQYPSETLDL--MAREICTIPCWQFIGWISQMMAMLDKKESIAVQHIIEEIAENYPQALVYPFMVSGENYNFEDTVVGHKNKEFVDRIKSKLDKDNVAQDFIHALEQLSNPPMIFQDWKEEVSNELSKASVNRN-------RVKELYKELCATLGNVKDPFMGAFRRRFSEKYTKEFDKAFGPDGSKLLSMKSDQFSKSAEPLMVKMRSEQQK--EPGNLKEYSPWM-------SGFKPEFL-RNELEIPGQYSG-RSKPMPEYHVKISGFDERVKVMASIRKPKRIIVRGNDEREYPFLVKGGEDLRQDQRIEQLFEIMNIILSQDAACSQRHMQL---KTYQVIPMTARIGLIEWMENTCTLKEFILNTMTEDEAKVYNR---------------------KCDRTSTVASFREREALVPK-DLLRRAFVKMSTTPEAFLSLRSHFARSHALLCISHWILGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLPVPELMPFRLTRQIVNLMLPMKESGIFDSVMVHSLRAYRSDPGLLITTMDVFIKEPSLDWKNLELKQIKKKGEWMKDVDTTSLNWYPAQKIHCAKRKLAGANPCEITCEELRLGHEGSPTYLAFLAVARGDKAHNKRANDPKDGLSEEAQVQCLIDQATDPNILGRVWKGWEP 4006 HSP 2 Score: 200.675 bits (509), Expect = 4.508e-50 Identity = 296/1342 (22.06%), Postives = 561/1342 (41.80%), Query Frame = 2
Query: 4799 IVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLA----LFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGP--FCNQ--DKVGLREKKLIGELSKICSLILYCKSDDSTNKLI-YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP----LFRHIIYKDYVINFPSEL------LIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNS-NLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSS---DVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGY-LFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSD-----FVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNI-PEWKND--SQINANVVKCFESCLPCSTQDEKKVRSLFFQLF-----VDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFV--NMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSA-VYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLK 8644
+V + NW ++D S++ + + + + LL +++ IDS++C + +F + ++L+ L + K++ I + F K G ++ + F NF + Y++ I L++ ++ ++ I CR+ H E+ + + + + ER + ++ LL +F E ++ + N+ ++ C L FF + I ++ +K + F +E +N I K++ +Y+ L C++ + + EL+K +LI C + N Q++ R + A+NC S++ S+ KFY L K +F ++I FP E+ + F +K + +T+ Y +D+ EP + S +++DSSL+ ++ + + S V S + D L ++ D +N H CM L M + I +V + D+P WMK H ++I+ FI KLI+N +F PYA FW+ +++ ++ S I+ V L I+ WSS+ ++K I N L+ +L +N + + ++ R N+E+ ++L WKE + IPY I++ + N G+++L VL N + F D + F + + K V+ A E+ G++L I + ++ +L A L R ++ F+ CL + KN R ++ ++ +L L + LEL+ M + + +LF +L + + + + + ++ ++ + P ++ S I A F C +++ +F ++ + S+ + + + LL G +D + ++ +RNF S LP+ T ER IL L+ S I +L++ATN++LEMTS PD+++ +F+ H S F++ T + L P FV + Q ++ M + P + ++F + P+Q I + S W + S++S +S + T + + +E + Y ++ + REKA++ IE+ +K A + LYRNY G+LP+I+I + IAPLQ LAQ + +K LF L++G+L E + L +QF++ L I+ + + ++LNP+ V + S + L +LLEK L+ H+ + + PPAKK++
Sbjct: 1589 LVNAVLQNWKRLD--SWWCKDSSPESKMAVLTLLAKVLQIDSSVCFDINHLAFAEVFRTYTSILTDQTLGLNLKSQAIIILPFFTKLTG---GKLTELKNTLDLFVASNFPMKCDEFPRGTLKFNNYVDCIKKFLDALEL-----SQSPMLLQLMTEILCRDERHFMEELFQSSFKKVIERSSCDAQVILLNTLHNMFTSESVMLNG--TLQSLTNRCLLTLLWNCSGDALLVFFTNIICLAMDTLK-SRFTKVSEAAFENQITKKWGYYKMLEVLYSRLSKDDICSKVNNAYHVSSNPEGNELTK--ALIKLCYDTFTENMCGETQLLEKRRQYHCAAYNCAISLISCVFSELKFYQGFLFTEKKEKNLLIFENLIDLQRSYTFPIEVESSYHEIYFDIKISFLFTI-----------YLNDE--DEPRYLSSQSYMADSSLSEEMSQFD--FSTGVQSFSYSSQDKMLSQRKTFDDVMEFEMDELNQHECMAAMTGLIKHMNSSEITPKVEEGASPQDLPPWMKFLHGKLGNTSTPLNIRLFIAKLIVNTEEVFCPYAKFWIGPMLQLIVSGNNGGSGIHYMVIETLVTILSWSSI-ATPKGLAKEEILANRLLEFLMKNVFHEKRAVYRHNLEIIKTVLECWKECLSIPYMLIYEGFSGTDPNTKDNSVGIQLLGLVLANNFSPFDQKCGIDAERYFQCLANNLALTRFKEVYIAAAEVIGLVLHYIYHNE--------KVSASDSLCCRAELKRHQTSNKEDKFIMCLNKVVKNFPPFADRFMTVVLYLLPKLHGVLKTQCLELI---MHRAEDIPDLFIELKNKEFCQIMNSRDDERQKVCLDIIYKILSKLKPAELHEFMSSIAAFNSHSFPVC-------RERMYEIFMWIYDNYRDQESQSDSKSVEVFSMAKEGLLQGLVDDNSELQLIVRNFWSDETRLPSNTTERMLAILSSLY--STKI--------EKHYLSLATNLLLEMTSKSPDYLRKMFE-HPLSECKFQDYTIDSSWRLRSTVLTPMFVETQLSQSMQRSRMQGTMEADEPEGGQLRATQQHFQFT--------PTQNIGGRS-----SFNWLTGSSMDTLADYSVESPESLPSALTPFFILRLRRRFLKDREK----------LSLIYARKGTAEQKREKAIK----------IEQKLKQDAQITLYRNYRHGELPDIQIAYSNLIAPLQALAQRDPTMAKLLFSSLFSGILSE------TASNASLIGKLLEQFNSFLSNSLSYFPPFIACVQDMCYQHDELLHLNPANVSTSCLASLQQPLGILLLEKGLL-HI-----EIPDEPPAKKMR 2825 HSP 3 Score: 179.104 bits (453), Expect = 1.463e-43 Identity = 255/1123 (22.71%), Postives = 456/1123 (40.61%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNI------VKSKKSSAKMKELSIKSLQDILTLTGNNN--FEMNIGVCLSDLFSQLQNKS--STTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNSKTSIISGCCEGLRRFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKS--YAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINY-LVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDN--NSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTI--LKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIF----------PILKNDILLMENEIFAMMYYLVECQRLSE 3535
E F D + +KF L ++ Y M+I V +K +AK K +++ L + L N+ E IG + + +L KS S TVL + EL+G + + P T S L L+ ++ T ++ ++FY + K+ I+ Y A+ + L+ L H + + + Q +F I K H N +K A LD +L+ I + ANN + + ++ QF ++KM ++K L I+G G C + K+ + ++Y + + + YL E D E+ +Y + + L S+ ++ + S P Y ++ RL + I+ P+ Y + + +L V S+I +V+Q +I CS P+ D E S + T +++ + + +D+L + +L+ + KD + L++D +K K+I++LDL + +D E +DP + PKDF FVNL + + + + W + Y LV +S LPLVSGFYK++ ++K + +F+ N + K A D L A+F + S KI + DELL +CLT +++ P I + + + + LQ+A +LG PL LD L+ W P ++ P Y+ ++ P+ Y N L+ T S+ ++ R +A++ N + L + + L L +L ++ +++W+ E + +++PF DIKP I L+ + ++ LAL+++ Q K A E+LHS++ +LGK A K+ + + F + ++LA D++KV+ L+ L+M + +WF+ ++ +++ + +DP + RD GQ + FL+ S + VN +R+Y L + + +KRLGA FN+I+ PI N N IF + CQ +
Sbjct: 68 EEFKDCREDALKFLSTFLEKIGSNVQPYAMDIKTLCVTVYTKDRAAKCKIPALELLIKLFQLLKNSYKIEEFKIGEIFNKFYGELATKSKLSDTVLEKVYELLGILGEVQPCEMTDNSEKLFKAFLGELKAQVFIHCTKLMKA-----KQFYS------NPKTSKEIF-----------DYTVKAI-TGLNLLALHASQFSNYLMDNYQSLFEVISKWCGHTNGEIKKLAFAALDSFLKQIAHLV----ANN--AEAHKNKLQFFMEQFYKVIRKMDC-----SNKELSIAIRGYGLFAAPCKAVNAKD-VDLMYIELIQRCKQMYLTEADTEED-------NVYQLPNFLQSVASVILRMDS--------IPEVYTPILERLLVLQIDSFPQYSLKMQYSCSKSVLKVFLSLAGKGPVLWSLISTVVHQGLIRVCSKPI---------------DIEGSEAEAAAATGEVRAGKWKVPTYKDYLDLFRNLLRCDQLKDSIFSDEIFSTLNSPLQSLNRLLYDELVKSILKVIEKLDLSLQKQDSGQENDGGINSSLIIATSDPAANLYPNKPKDFTAFVNLVEFCSEILPKEHIEYFESWV-YAFGYELVLQSTRLPLVSGFYKLLSVVMKNVKKIRYFEGFNSKTYKKAPEDPERLSCFALFAKFGKEVSS---KIRQFKDELLASCLTFVLHLPHDIIMMDIKAY------IPALQIAFKLGLSCPPLADVGLDALQDWSTYIPS-----DILQPYYKDII---PLLDG--YLTN----------------LSSTDESLSDLDAVRISRALQKGFNKHLIQQLKRTKTLSVVLYFVL---------FIATSTEEMIKCHVSWDT--EKRLTFDVPFMDIKPVIYLDTFLPRVTELALSASDRQTKVAACELLHSIVAFMLGKAAQMPDDKKMGSSPMYKLYKRTFPVLLRLACDVDKVTMQLYKPLVMSLIHWFTNNKKFESQDTVALLEAILAGI-------------VDPVDSTL-RDFCGQCIQEFLRWSIKQTTPEQQAKSPVN--TTSLFKRLYSLALHPNAFKRLGAALAFNNIYREFREMAEKKPIPHNFFAYHYNSIFISCFMPSICQSFGQ 1062
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:100488663]) HSP 1 Score: 394.045 bits (1011), Expect = 1.393e-108 Identity = 246/770 (31.95%), Postives = 400/770 (51.95%), Query Frame = 2
Query: 9935 GLLNKSFYCFNKIISMYSESDGNK-------KELSAALVVVSDFYDAQIRQFEN--------DGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML------YVADVTSKSN--FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKI---IGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHR------------MSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKY-GKSNWFKCMKNFQSEDA-------------ETSQTKKLVSMATNSGFLARTWQGFEP 12088
GL KS + F + +E + + + + A + + DF D+ +R+ E D P+++ VE + ++KL A+ KFPR+LQII Q+ + D + +IP W +I W+ QM+ LD S V+ II IA++YP AL YPFM+ + V N F+ +I L + F AL Q+ P Q W +E ++ S S + N + +++Y+++ +GN+ G F+ FS+ + + F DG+ + ++ +QFS+ + ++++ + K E NLK++SPW+ S ++P+ + ++ LEIPGQY+ ++P PE H+KI + +++M S + PK+II+ G++E+ Y FLVK GEDLRQD RIEQ+F +MN I+S+D ++ L KTY VIP++ +GL+EW++NT TL EF TM ++E +Y + K D ST F E + L+ DLLR++F+ +S E+F LR +F + +A+ +H++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT +V + P GIF + + L + +++ M VF+ LDW M + S+ + ++I+ + RKL +P + EEL++ + G + + + + A E +Q + L+ AT+ L R W+G+EP
Sbjct: 3281 GLYRKSLHYFMNAVRKATEEEQSHSIDKVDVRGIIKAYMTLVDFCDSHLRKVEEKSAVMDHADYQHFPEIM---VEKMIKALKLNSSEARLKFPRMLQIIEQYPSETLDL--MAREICTIPCWQFIGWISQMMAMLDKKESIAVQHIIEEIAENYPQALVYPFMVSGENYNFEDTVVGHKNKEFVDRIKSKLDKDNVAQDFIHALEQLSNPPMIFQDWKEEVSNELSKASVNRN-------RVKELYKELCATLGNVKDPFMGAFRRRFSEKYTKEFDKAFGPDGSKLLSMKSDQFSKSAEPLMVKMRSEQQK--EPGNLKEYSPWM-------SGFKPEFL-RNELEIPGQYSG-RSKPMPEYHVKISGFDERVKVMASIRKPKRIIVRGNDEREYPFLVKGGEDLRQDQRIEQLFEIMNIILSQDAACSQRHMQL---KTYQVIPMTARIGLIEWMENTCTLKEFILNTMTEDEAKVYNR---------------------KCDRTSTVASFREREALVPK-DLLRRAFVKMSTTPEAFLSLRSHFARSHALLCISHWILGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLPVPELMPFRLTRQIVNLMLPMKESGIFDSVMVHSLRAYRSDPGLLITTMDVFIKEPSLDWKNLELKQIKKKGEWMKDVDTTSLNWYPAQKIHCAKRKLAGANPCEITCEELRLGHEGSPTYLAFLAVARGDKAHNKRANDPKDGLSEEAQVQCLIDQATDPNILGRVWKGWEP 4002 HSP 2 Score: 191.815 bits (486), Expect = 1.881e-47 Identity = 299/1369 (21.84%), Postives = 565/1369 (41.27%), Query Frame = 2
Query: 4799 IVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLA----LFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGP--FCNQ--DKVGLREKKLIGELSKICSLILYCKSDDSTNKLI-YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNS-NLMDSDSFLQHDGRCLM----IINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSS---DVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGY-LFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSD-----FVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNI-PEWKND--SQINANVVKCFESCLPCSTQDEKKVRSLFFQLFV---------DLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFV--NMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKD-----------EYSMEWSSSQIPGVDMSLSIKSQKSFL--------NLSTSVMHIENEDKASNQQEN------QTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSA-VYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLK 8644
+V + NW ++D S++ + + + + LL +++ IDS++C + +F + ++L+ L + K++ I + F K G ++ + F NF + Y++ I L++ ++ ++ I CR+ H E+ + + + + ER + ++ LL +F E ++ + N+ ++ C L FF + I ++ +K + F +E +N I K++ +Y+ L C++ + + EL+K +LI C + N Q++ R + A+NC S++ S+ KFY L K +F ++I FP E+ I + +T+ Y +D+ EP + S +++DSSL+ ++ + + S V S + D L ++ D +N H CM L M + I +V + D+P WMK H ++I+ FI KLI+N +F PYA FW+ +++ ++ S I+ V L I+ WSS+ ++K I N L+ +L +N + + ++ R N+E+ ++L WKE + IPY I++ + N G+++L VL N + F D + F + + K V+ A E+ G++L I + ++ +L A L R ++ F+ CL + KN R ++ ++ +L L + LEL+ M + + +LF +L + + + + + ++ ++ + P ++ S I A F C R +++F+ + S+ + + + LL G +D + ++ +RNF S LP+ T ER IL L+ S I +L++ATN++LEMTS PD+++ +F+ H S F++ T + L P FV + Q ++ M + P + ++F + P+Q I + + +YS+E S +P + ++ +++K N T + + +E + F + + Y ++ + REKA+ KIE+ +K A + LYRNY G+LP+I+I + IAPLQ LAQ + +K LF L++G+L E + L +QF++ L I+ + + ++LNP+ V + S + L +LLEK L+ + + PPAKK++
Sbjct: 1553 LVNAVLQNWKRLD--SWWCKDSSPESKMAVLTLLAKVLQIDSSVCFDINHLAFAEVFRTYTSILTDQTLGLNLKSQAIIILPFFTKLTG---GKLTELKNTLDLFVASNFPMKCDEFPRGTLKFNNYVDCIKKFLDALEL-----SQSPMLLQLMTEILCRDERHFMEELFQSSFKKVIERSSCDAQVILLNTLHNMFTSESVMLNG--TLQSLTNRCLLTLLWNCSGDALLVFFTNIICLAMDTLK-SRFTKVSEAAFENQITKKWGYYKMLEVLYSRLSKDDICSKVNNAYHVSSNPEGNELTK--ALIKLCYDTFTENMCGETQLLEKRRQYHCAAYNCAISLISCVFSELKFYQGFLFTEKKEKNLLIFENLIDLQRSYTFPIEVEI-----SFLFTI-----------YLNDE--DEPRYLSSQSYMADSSLSEEMSQFD--FSTGVQSFSYSSQDKMLSQSASRKKTFDDVMEFEMDELNQHECMAAMTGLIKHMNSSEITPKVEEGASPQDLPPWMKFLHGKLGNTSTPLNIRLFIAKLIVNTEEVFCPYAKFWIGPMLQLIVSGNNGGSGIHYMVIETLVTILSWSSI-ATPKGLAKEEILANRLLEFLMKNVFHEKRAVYRHNLEIIKTVLECWKECLSIPYMLIYEGFSGTDPNTKDNSVGIQLLGLVLANNFSPFDQKCGIDAERYFQCLANNLALTRFKEVYIAAAEVIGLVLHYIYHNE--------KVSASDSLCCRAELKRHQTSNKEDKFIMCLNKVVKNFPPFADRFMTVVLYLLPKLHGVLKTQCLELI---MHRAEDIPDLFIELKNKEFCQIMNSRDDERQKVCLDIIYKILSKLKPAELHEFMSSIAAFNSHSFPVC-----------RERMYEIFMWIYDNYRDQESQSDSKSVEVFSMAKEGLLQGLVDDNSELQLIVRNFWSDETRLPSNTTERMLAILSSLY--STKI--------EKHYLSLATNLLLEMTSKSPDYLRKMFE-HPLSECKFQDYTIDSSWRLRSTVLTPMFVETQLSQSMQRSRMQGTMEADEPEGGQLRATQQHFQFT--------PTQNIGGRSSFNWLTGSSMDTLADYSVE-SPESLPSALLFVNKRNEKVRRGPLKPLGPNFGTQKLGLPGHVTEKGIEERSEILRLRRRFLKDREKLSLIYARKGTAEQKREKAI----------KIEQKLKQDAQITLYRNYRHGELPDIQIAYSNLIAPLQALAQRDPTMAKLLFSSLFSGILSE------TASNASLIGKLLEQFNSFLSNSLSYFPPFIACVQDMCYQHDELLHLNPANVSTSCLASLQQPLGILLLEKGLL------HIEIPDEPPAKKMR 2821 HSP 3 Score: 190.274 bits (482), Expect = 6.395e-47 Identity = 251/1093 (22.96%), Postives = 447/1093 (40.90%), Query Frame = 2
Query: 434 VKSKKSSAKMKELSIKSLQDILTLTGNNNF--EMNIGVCLSDLFSQLQNKS--STTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEI----NNSKTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKS--YAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINY-LVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDN--NSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTI--LKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIF----------PILKNDILLMENEIFAMMYYLVECQRLSE 3535
V +K +AK K +++ L + L N+ E IG + + +L KS S TVL + EL+G + + P T S L L+ ++ N K +I+GC +GL F K + E K+ I+ +K + + L+ L H + + + Q +F I K H N +K A LD +L+ I + ANN + + ++ QF ++KM ++K L I+G G C + K+ + ++Y + + + YL E D E+ +Y + + L S+ ++ + P Y ++ RL + I+ P+ Y + + +L V S+I +V+Q +I CS P+ D E S + T +++ + + +D+L + +L+ + KD + L++D +K K+I++LDL + +D E +DP + PKDF FVNL + + + + W + Y LV +S LPLVSGFYK++ ++K + +F+ N + K A D L A+F + S KI + DELL +CLT +++ P I + + + + LQ+A +LG PL LD L+ W P ++ P Y+ ++ P+ Y N L+ T S+ ++ R +A++ N + L + + L L +L ++ +++W+ E + +++PF DIKP I L+ + ++ LAL+++ Q K A E+LHS++ +LGK A K+ + + F + ++LA D++KV+ L+ L+M + +WF+ ++ +++ + +DP + RD GQ + FL+ S + VN +R+Y L + + +KRLGA FN+I+ PI N N IF + CQ +
Sbjct: 50 VYTKDRAAKCKIPALELLIKLFQLLKNSYKIEEFKIGEIFNKFYGELATKSKLSDTVLEKVYELLGILGEVQPCEMTDNSEKLFKAFLGELKAQMISSTRNPKFPVIAGCLKGLSALMINFTKTMEE--DPKTSKEIFDYTVKAI------------TGLNLLALHASQFSNYLMDNYQSLFEVISKWCGHTNGEIKKLAFAALDSFLKQIAHLV----ANN--AEAHKNKLQFFMEQFYKVIRKMDC-----SNKELSIAIRGYGLFAAPCKAVNAKD-VDLMYIELIQRCKQMYLTEADTEED-------NVYQLPNFLQSVASVI--------LRMDSIPEVYTPILERLLVLQIDSFPQYSLKMQYSCSKSVLKVFLSLAGKGPVLWSLISTVVHQGLIRVCSKPI---------------DIEGSEAEAAAATGEVRAGKWKVPTYKDYLDLFRNLLRCDQLKDSIFSDEIFSTLNSPLQSLNRLLYDELVKSILKVIEKLDLSLQKQDSGQENDGGINSSLIIATSDPAANLYPNKPKDFTAFVNLVEFCSEILPKEHIEYFESWV-YAFGYELVLQSTRLPLVSGFYKLLSVVMKNVKKIRYFEGFNSKTYKKAPEDPERLSCFALFAKFGKEVSS---KIRQFKDELLASCLTFVLHLPHDIIMMDIKAY------IPALQIAFKLGLSCPPLADVGLDALQDWSTYIPS-----DILQPYYKDII---PLLDG--YLTN----------------LSSTDESLSDLDAVRISRALQKGFNKHLIQQLKRTKTLSVVLYFVL---------FIATSTEEMIKCHVSWDT--EKRLTFDVPFMDIKPVIYLDTFLPRVTELALSASDRQTKVAACELLHSIVAFMLGKAAQMPDDKKMGSSPMYKLYKRTFPVLLRLACDVDKVTMQLYKPLVMSLIHWFTNNKKFESQDTVALLEAILAGI-------------VDPVDSTL-RDFCGQCIQEFLRWSIKQTTPEQQAKSPVN--TTSLFKRLYSLALHPNAFKRLGAALAFNNIYREFREMAEKKPIPHNFFAYHYNSIFISCFMPSICQSFGQ 1023
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: PRKDC (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:100488663]) HSP 1 Score: 381.719 bits (979), Expect = 6.432e-105 Identity = 237/762 (31.10%), Postives = 396/762 (51.97%), Query Frame = 2
Query: 9935 GLLNKSFYCFNKIISMYSESDGNK-------KELSAALVVVSDFYDAQIRQFEN--------DGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKI---IGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHR------------MSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKY-GKSNWFKCMKNFQSEDA-------------ETSQTKKLVSMATNSGFLARTWQGFEP 12088
GL KS + F + +E + + + + A + + DF D+ +R+ E D P+++ VE + ++KL A+ KFPR+LQII Q+ + D + +IP W +I W+ QM+ LD S V+ II IA++YP AL YPFM+ + + + K + K + +++ + + W +E ++ S S + N + +++Y+++ +GN+ G F+ FS+ + + F DG+ + ++ +QFS+ + ++++ + K E NLK++SPW+ S ++P+ + ++ LEIPGQY+ ++P PE H+KI + +++M S + PK+II+ G++E+ Y FLVK GEDLRQD RIEQ+F +MN I+S+D ++ L KTY VIP++ +GL+EW++NT TL EF TM ++E +Y + K D ST F E + L+ DLLR++F+ +S E+F LR +F + +A+ +H++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT +V + P GIF + + L + +++ M VF+ LDW M + S+ + ++I+ + RKL +P + EEL++ + G + + + + A E +Q + L+ AT+ L R W+G+EP
Sbjct: 3255 GLYRKSLHYFMNAVRKATEEEQSHSIDKVDVRGIIKAYMTLVDFCDSHLRKVEEKSAVMDHADYQHFPEIM---VEKMIKALKLNSSEARLKFPRMLQIIEQYPSETLDL--MAREICTIPCWQFIGWISQMMAMLDKKESIAVQHIIEEIAENYPQALVYPFMVSGENYNFEDTVVGHKNKEFVDRKQIFKYH-----------FFKDWKEEVSNELSKASVNRN-------RVKELYKELCATLGNVKDPFMGAFRRRFSEKYTKEFDKAFGPDGSKLLSMKSDQFSKSAEPLMVKMRSEQQK--EPGNLKEYSPWM-------SGFKPEFL-RNELEIPGQYSG-RSKPMPEYHVKISGFDERVKVMASIRKPKRIIVRGNDEREYPFLVKGGEDLRQDQRIEQLFEIMNIILSQDAACSQRHMQL---KTYQVIPMTARIGLIEWMENTCTLKEFILNTMTEDEAKVYNR---------------------KCDRTSTVASFREREALVPK-DLLRRAFVKMSTTPEAFLSLRSHFARSHALLCISHWILGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLPVPELMPFRLTRQIVNLMLPMKESGIFDSVMVHSLRAYRSDPGLLITTMDVFIKEPSLDWKNLELKQIKKKGEWMKDVDTTSLNWYPAQKIHCAKRKLAGANPCEITCEELRLGHEGSPTYLAFLAVARGDKAHNKRANDPKDGLSEEAQVQCLIDQATDPNILGRVWKGWEP 3957 HSP 2 Score: 211.46 bits (537), Expect = 2.564e-53 Identity = 245/1015 (24.14%), Postives = 434/1015 (42.76%), Query Frame = 2
Query: 524 EMNIGVCLSDLFSQLQNKS--STTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEI----NNSKTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK-----INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINY-LVTRSLELPLVSGFYKMICSIIKILDSFGFFQI-NLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTL--LLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTI--LKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIF 3448
E IG + + +L KS S TVL + EL+G + + P T S L L+ ++ N K +I+GC +GL F K + E K+ I+ Y A+ + L+ L H + + + Q +F I K H N +K A LD +L+ I + ANN + + ++ QF ++KM ++K L I+G G C + K+ + ++Y + + + YL E D E+ +Y + + L S+ ++ + S P Y ++ RL + I+ P+ Y + + +L V S+I +V+Q +I CS P+ D + + F+YS + +Y +D+L + +L+ + KD + L++D +K K+I++LDL + +D E +DP + PKDF FVNL + + + + W + Y LV +S LPLVSGFYK++ ++K + +F++ L C A+F + S KI + DELL +CLT +++ P I + + + + LQ+A +LG PL LD L+ W P ++ P Y+ + LL +++ D + L A R SR L + +I+Q + + + + + +SL + NR++RILG +G +R L+ S +++W+ E + +++PF DIKP I L+ + ++ LAL+++ Q K A E+LHS++ +LGK A K+ + + F + ++LA D++KV+ L+ L+M + +WF+ ++ +++ + +DP + RD GQ + FL+ S + VN +R+Y L + + +KRLGA FN+I+
Sbjct: 105 EFKIGEIFNKFYGELATKSKLSDTVLEKVYELLGILGEVQPCEMTDNSEKLFKAFLGELKAQMISSTRNPKFPVIAGCLKGLSALMINFTKTMEE--DPKTSKEIF-----------DYTVKAI-TGLNLLALHASQFSNYLMDNYQSLFEVISKWCGHTNGEIKKLAFAALDSFLKQIAHLV----ANN--AEAHKNKLQFFMEQFYKVIRKMDC-----SNKELSIAIRGYGLFAAPCKAVNAKD-VDLMYIELIQRCKQMYLTEADTEED-------NVYQLPNFLQSVASVILRMDS--------IPEVYTPILERLLVLQIDSFPQYSLKMQYSCSKSVLKVFLSLAGKGPVLWSLISTVVHQGLIRVCSKPI--------DIAQVSNSFKYSFTYIRAGKWKVPTY-----KDYLDLFRNLLRCDQLKDSIFSDEIFSTLNSPLQSLNRLLYDELVKSILKVIEKLDLSLQKQDSGQEVSSLIIATSDPAANLYPNKPKDFTAFVNLVEFCSEILPKEHIEYFESWV-YAFGYELVLQSTRLPLVSGFYKLLSVVMKNVKKIRYFEVKRLSCF-----------ALFAKFGKEVSS---KIRQFKDELLASCLTFVLHLPHDIIMMDIKAY------IPALQIAFKLGLSCPPLADVGLDALQDWSTYIPS-----DILQPYYKDIIPLLDGYLTNLSSTDESLSDLD----AVRISRALQKGFNK-HLIQQLKRTKTLS--VKEESSL---AAVSNRVVRILGSLGGQINRSLVTATSTEEMIKCHVSWDT--EKRLTFDVPFMDIKPVIYLDTFLPRVTELALSASDRQTKVAACELLHSIVAFMLGKAAQMPDDKKMGSSPMYKLYKRTFPVLLRLACDVDKVTMQLYKPLVMSLIHWFTNNKKFESQDTVALLEAILAGI-------------VDPVDSTL-RDFCGQCIQEFLRWSIKQTTPEQQAKSPVN--TTSLFKRLYSLALHPNAFKRLGAALAFNNIY 1011 HSP 3 Score: 186.422 bits (472), Expect = 7.554e-46 Identity = 232/1015 (22.86%), Postives = 431/1015 (42.46%), Query Frame = 2
Query: 5747 AFNCFSSVVIATQSDEKFYTNLLLRYNKP----LFRHIIYKDYVINFPSELLIFKMKQ-TKFYTLNKEKPIF-NSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKL-----ENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSS---DVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGY-LFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNI-PEWKND--SQINANVVKCFESCLPCSTQDEKKVRSLFFQLF-----VDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFV--NMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQE-----------------NQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSA-VYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLK 8644
A+NC S++ S+ KFY L K +F ++I FP E+ + K K TK + +P + +S Y +D S++E +S + V+ + +LS++ + D ++ D +N H CM L M + I +V + D+P WMK H ++I+ FI KLI+N +F PYA FW+ +++ ++ S I+ V L I+ WSS+ ++K I N L+ +L +N + + ++ R N+E+ ++L WKE + IPY I++ + N G+++L VL N + F D + F + + K V+ A E+ G++L I + + ++T++ + + F+ CL + KN R ++ ++ +L L + LEL+ M + + +LF +L + + + + + ++ ++ + P ++ S I A F C +++ +F ++ + S+ + + + LL G +D + ++ +RNF S LP+ T ER IL L+ S I +L++ATN++LEMTS PD+++ +F+ H S F++ T + L P FV + Q ++ M + P + ++F + P+Q I + S W + S++S +S L ++++ + ++ + + TE +T E + L + +++ + L+ KIE+ +K A + LYRNY G+LP+I+I + IAPLQ LAQ + +K LF L++G+L E + L +QF++ L I+ + + ++LNP+ V + S + L +LLEK L+ H+ + + PPAKK++
Sbjct: 1868 AYNCAISLISCVFSELKFYQGFLFTEKKEKNLLIFENLIDLQRSYTFPIEVEVSKKKNLTKAFLFVIYEPRYLSSQSYMADS-------SLSEEMSQFDFSTGVQSFSYSSQDKMLSQSASRKKTFDD-----------VMEFEMDELNQHECMAAMTGLIKHMNSSEITPKVEEGASPQDLPPWMKFLHGKLGNTSTPLNIRLFIAKLIVNTEEVFCPYAKFWIGPMLQLIVSGNNGGSGIHYMVIETLVTILSWSSI-ATPKGLAKEEILANRLLEFLMKNVFHEKRAVYRHNLEIIKTVLECWKECLSIPYMLIYEGFSGTDPNTKDNSVGIQLLGLVLANNFSPFDQKCGIDAERYFQCLANNLALTRFKEVYIAAAEVIGLVLHYIYHNEKVSA----------SVTYKLGQTNKEDKFIMCLNKVVKNFPPFADRFMTVVLYLLPKLHGVLKTQCLELI---MHRAEDIPDLFIELKNKEFCQIMNSRDDERQKVCLDIIYKILSKLKPAELHEFMSSIAAFNSHSFPVC-------RERMYEIFMWIYDNYRDQESQSDSKSVEVFSMAKEGLLQGLVDDNSELQLIVRNFWSDETRLPSNTTERMLAILSSLY--STKI--------EKHYLSLATNLLLEMTSKSPDYLRKMFE-HPLSECKFQDYTIDSSWRLRSTVLTPMFVETQLSQSMQRSRMQGTMEADEPEGGQLRATQQHFQFT--------PTQNIGGRS-----SFNWLTGSSMDTLADYSVESPES---LPSALLFVNKRNEKVRRGPLKPLGPNFGTQKLGLPGHVTESKTKKGIEERSEILRLRRRFLKDRE---KLSLIYAIKIEQKLKQDAQITLYRNYRHGELPDIQIAYSNLIAPLQALAQRDPTMAKLLFSSLFSGILSE------TASNASLIGKLLEQFNSFLSNSLSYFPPFIACVQDMCYQHDELLHLNPANVSTSCLASLQQPLGILLLEKGLL-HI-----EIPDEPPAKKMR 2801
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkdc (protein kinase, DNA activated, catalytic polypeptide [Source:MGI Symbol;Acc:MGI:104779]) HSP 1 Score: 572.392 bits (1474), Expect = 7.423e-163 Identity = 647/2642 (24.49%), Postives = 1154/2642 (43.68%), Query Frame = 2
Query: 4820 NWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNIC----ENNF--IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDR----NFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL--------IGELSKICSLILYCKSDDSTNKLI--YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDS----------------DSFLQHDGRCLMIINIPYDIVNDHPCMDTFICL-HHQMKNV--GIISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK--MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSS---EKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLT----------------------ASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREK-AVXXXXXXXXXXXIEKNIK-------NSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIP-------YLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKAD-CFGXXXXXXXXXXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKS-------------VVNSKLRTLVFEKNVDEGHT--ISELDELV-KRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQK-CDM----PIDYISKLKGNQ-GDLEKESLEFWENLLFYRTVYLKK-----------GMMKFPFLAEAITTEISD---------------LQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAP-EILIGLTNSVKLLLK-----FPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQ--SEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSE-------SDGNKKELSAALVVVSDFYDAQIRQFENDGPSR--------PDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEF-KNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY---KKVSSEFYTQYF------PNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMK---------NFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
NW + D S++ P+ + + LL +M+ IDS + ++F IF + +LL+ T L + K + I + F + EGS +EN+K ++ NF S + D Y++ + L++ ++ ++ I CRE H E+ + T + + + ++ LL + N+ F+++ ++ CD+ L FF + ++ +K + F NE I K+++ +Y+ L +D V +E K+ + E +++ +L D T ++ Q++ R + A+NC S++ ++ KFY L KP +F ++I FP E+ + ++ K+ + KE + S Y S +L+DSSL+ ++ + + S V S S DS Q D I+ + D +N H CM I L H +NV E + D+P WMK HD ++I+ F+ KL+IN +F+PYA W+ L++ + + I+ + ++ I+ W+ + V K + N L+ +L ++ + ++ R N+E+ +L+ WKE + IPY+ IF+ + + N G+++L V+ N + T + + LV + K V+ A E+ G++L+ I + +E V E+ + + + + F+ CL I K + R ++ L +L LE++ C + E L+ QL + + ++++ + + ++ + + + +N VV+ P + + + D S E +F + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMT PD++ PIF+ H S F+ T S +++QT L + P ++R+ +D PT ++ + + FDW+ +S + + + + S + + + T + + + D+ NQ ++ T Q + + K+ REK ++ K L +QK+EK+IK ++ V LYR+Y G LP+I+IQ+ I PLQ +AQ + +K LF L++G+LKE F + QNL Q F+ L T + +S +I+ + + L+P AS G LA++ + ++ + PP K+++ G + +P L KLY+ +++ + +L ++++ ++D C L + E + +EL S +D L KW EL C +S + +++K V+ SKL+ L+ EG+ ++ +DE + K Q ++ EL E+SL YI+++D ++A + + + +YS L + LQS+ L EI +FL + K D+ P+ + K ++ D+ + + W++++ R +L K M E+I E+ + ++M+ I++ + S + LK K SK + +H S + H S ++P E ++ + ++ LL + + N +I S + + LG + + LS S+ E +NSIL L + T +++I GL ++F+ +K + E E + A + + F D Q+R+ E + P L+ VE L ++KL A+ KFPRLLQII Q++ + N +T SSIP W +I W+ M+ LD + V+ + IAD+YP A+ YPF++ Y TS + F+ +I L + +++H F AL Q+ P+ + W+ + D N + ++NI Y+ MY +G+L G F+ F + F + +F G+ + T+ + F +I + ++K K S+ NLK++SPW++++ + K+ LEIPGQY+ ++P PE H++I + +++M S + PK+I+I G +E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ L +TY V+P++ LGL+EWI+NT+TL + M EE+ K Y + + AY + +++ T F ++ + DLL+++F+ +S E+F LR +F +A+ +H+LLGIGDRHL NF++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT V + P G+ + + L + M +F+ DW M R I+ + Q +I + RKL +P ++ +EL + + S+ F+ N ++++ E+ +Q K LV AT+ L RTW+G+EP
Sbjct: 1622 NWRKCD--SWWAPDSAPESKTTVLSLLAKMLQIDSALSFDTNHSSFSEIFTTYASLLADTKLGLHLKGQAIILLPFF---TSLREGS----LENLKHILEKLIVCNFPMKSDEFPPDSLKYNNYVDCMKKFLDALEL-----SQSPMLFQLMTDILCREQRHIMEELFQTTFKRIARQSPCVTQLNLLESVYTMFRKADLPSNVTRQAFVDRSLLTLLWHCDLDTLKEFFSRIVVDAIDVLK-SRFTKLNEFTFDTQITKKMCYYKMLAVMYSRL----LKDDVHSKEAKINQAFHGSRVAEGNELTKTLLKLCHDAFTENMVGESQLLEKRRLYHCAAYNCAISLISCVFNELKFYQGFLFN-EKPEKNLFIFENLIDLKRCYTFPIEVEVPMERKKKYIEIRKEARDAANGASGSPHYM-----SSLSYLTDSSLSEEMSQFD--FSTGVQSYSYSSQDRKPTTGHFQRREHQDSMTQDD-----IMELEMDELNQHECMAPMIALIKHMQRNVIAPKGEEGSIPKDLPPWMKFLHDKLGNASVSLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAVCENNREGIHYMMVEIVATILSWTGL-ATPTGVPKDEVLANRLLRFLMKHVFHPKRAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSHKDPNSKDNSVGIQLLGIVIANNLPPYDPNCDITSAMYFEALVNNMSFVKYKEVYAAAAEVLGLILQYITERKHVIAELVCEL---VIKQLKQHQNTMEDKFIVCLNKIAKGFPPLADRFLNALFFLLPKFHGVMKTLCLEVVLC---RAEEITGLYLQLKSKDFLQVMRHRDDERQKVCLDIVYKMVAKLKPIELRELLNP-VVEFVSHPSPTCREQMYNILMWIHDNYRDQESQNDEDSQEIF-KLAKDVLIQGLIDENVGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTRMSPDYLNPIFE-HPLSECEFQEYTIDPDWRFRSTVLTPMFIETQASPSILHTQTQEGPLSDQRQKPGQVRATQQQYD---FTPTQASVERSS--FDWLTGSSIDLLADHTVFSSETLSSSLLFSHKR----TEKSQRMSCKSVGPDFGTKKLGLPD-DEVDNQVKSGTPSQADILRLRRRFLKD------REKLSLLYAKRGLMEQKLEKDIKSEFKMKQDAQVVLYRSYRHGDLPDIQIQHSGLITPLQAVAQKDPIIAKQLFSSLFSGILKEMNKFKTTSEKNIITQNLLQDFNRFLNTTFLFFPPFVSCIQEISCQHPDFLTLDP-----ASVRVG--CLASLQQPGGIRLLEEALLRLMPKEPPTKRVR------GKTCLPPDVLRWMELAKLYR-SIGEYDVLRGIFSSELGTTQDTQNALLAEARSDYCQAAKLYDEALNKLEWVDGEPTEAEKEFWELAS------LDCYNNLSKWKELE---YCSTVNIVSENSLDLSKMWSEPFYQETYLPYVIRSKLKLLL----QGEGNQSLLTFVDEAMNKELQKTV--LELQYSQELSLLYILQDDIDRATYYIKNGIQIFMQ---NYSSIDVLLYRSRLAKLQSVQTLAEIEEFLSFICKHGDLSSLGPLRRLLKTWTSRYPDVVTDPMHIWDDIITNRCFFLSKIEERLTAPSGDHSMSVDEDEESIDREVYEPKEDVRCMLQSCRFTMKMKMIESAWKQSNFSLSMKLLKEM-------HKESKTREIWRVQWLHSYSQLNHCR--SHTQSPREQVLNMLKTITLLDESDISNYLNKNIQASCDQSILLGTTCRIMADALSREPACLSDLEENKVNSILTLSGSNAENT-ETVITGLYQRAFHHLSKAVQSAEEETQLSCWGHEAAAERAHAYMTLVGFCDQQLRKVEESASQKTSAEMEAYPALV---VEKMLRALKLNSSEARLKFPRLLQIIEQYSEETL--NIMTKEISSIPCWQFIGWISHMMALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFKNTSSGHNNKAFVERIKSKLDHGEVIHSFINALDQLSNPDLLFKDWVSDTKDELGKNPVN---KKNIEKLYERMY-AALGDLRAPGLGPFRRRFIQAFGKEFVKSFGNGGSKLLTMKVDDFCKITGSLLVRMK----KDSKLPGNLKEYSPWMSEFKAQ--------FLKNELEIPGQYDG-KSKPLPEYHVRISGFDERVKVMLSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQIFEVMNAILSQDAACSQRNMQL---RTYRVVPMTSRLGLIEWIENTMTLKDLLLSNMSQEEKVANNSDPKAPIRDYKDWLMKVSGKSDAGAYVLMYSRANRTETVVAFRRRESQVPP-DLLKRAFVKMSTSPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFLPVPELMPFRLTRQFVSLMLPMKETGLMCTVMVHALRAFRSCAGLLTDTMEIFVKEPSFDWKSFEQTMLRKGGSWIQEINVTEKNWYPQHKIRYAKRKLAGANPAVITCDELYLGHEASSAFRSYTAVARGNRDYNIRAQEPESGLSEETQVKCLVDQATDPNILGRTWEGWEP 4126 HSP 2 Score: 213.386 bits (542), Expect = 4.578e-54 Identity = 280/1273 (22.00%), Postives = 545/1273 (42.81%), Query Frame = 2
Query: 335 IENFCDFIINLVKF-------AKEKLLPFCGLIKNYLMNIVKSKKSSAKMKELSIKSLQDILTLTGNNNF--EMNIGVCLSDLFSQLQNKSS--TTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMD-SGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV--PPDFSIIQD---FSLNISDFEYSINTDSNETDLIKSYAAL-STRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPH--MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNK---LEKLQNRLIRILGKMGINYSRYLIRDNS-RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENI-KFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIF-AMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQ---SFCWL-LSMNLIDAYNYF 3982
IE+F D +KF +K++ + IKN + V +K +AK K ++ L +L + + E IG + + +L +KS TVL + EL+G + ++P+ ++S + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ K + R+A + L LT H + + + +F + K +H NV LK +A + L+ +L QI F + + +Y QF ++ S +K L I+G G C V+ K+ + +Y + + + +L D + +P + + IA +L+ L + + P ++ + F ++SP++ ++F A+ + H + I +V+Q +I CS PV D D S + + + T + DL + DF+ L N + L++D F++ KI+++LDL + + V ++ +DP + P DF +NL + + + + + W L+ +S LPL+SGFYK++ +K +F+ I+ + K + D A+F + K+ Y DELL +CLT +++ P I ++ + P LQMA +LG ++PL + L L+ W + + K ILP L S +S + + L A K +R + + L+ + N+S ++ LE+++ ++++ILG +G ++ L+ S + W+ E + + +PF+++KP I L+ + ++ LAL+++ Q K A E+LHS+++ +LG+ AT + + + + + + F + ++LA D+++V++ L+ L+MQ+ +W + ++ +++ D + +DP + RD G+ + FLK S + VN K +R+Y L + + +KRLGA FN I+ + + L+E +F A++ Y+ E++K LGT+ Q A ++ K ++ +K R +P P T+ + + WLL + + R ++L + + +P+ + K L+ K + ++ FE P+ + A + L+ + WL L + ++ YN F
Sbjct: 75 IEDFRDCREEALKFLCVFLEKIDQKVMHYSLDIKNTCTS-VYTKDRTAKCKIPALDLLIKLLQILRSTRLMDEFKIGELFNKFYGELASKSKLPDTVLEKVYELLGVLGEVHPSEMINHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEE--DPQTSKEIFGFTFKAIRPQIEMKRYAVPLAGLRLLTLHASQFTACLLDNYITLFEVLSKWCSHTNVELKKAAHSALESFLR------QISFTVAEDAELHKSRLKYFMEQFYGIIRNTDS-----NNKELAIAIRGYGLFAGPCKVINAKD-VDFMYVELIQRCKQMFLTHADASEDHVYQMPSF-LQSIASVLLYLDTVPEVYT----------PVLEHLMVVQIDSFPQYSPKMQLVCCKAIIKLFLALSEKGPVH----WNCISAVVHQGLIRICSKPVVLQKDVESRSDNRSASEEVRTGRWKVPTYKDYVDLFQHLLGCDQMEDFILGDETFLFVNSSLKSLNHLLYDEFIRSVLKIVEKLDLTLEKQTVGEQEDGSTADVWVIPTSDPAANLHPAKPSDFSALINLVEFCREILPRKHVGFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGISPKSLKHSPEDTEKYSCFALFAKFGKEVSV---KMKQYKDELLASCLTFVLSLPHDIIELDVRAYVP-------ALQMAFKLGLSHMPLAEIGLHALKEWSVHIDKSILQPYYKDILPCLDGYLNTSTLSDETKSHWGLSALSR-AAQKGFNRHVVKHLKRTR-----------------NSSPDEALSLEEIRIKVVQILGSLGGQINKSLVTATSGERMKKYVAWDA--ERRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVMFMLGR-ATQMPEGQGLPPMYQLYKHTFPVLLQLACDVDQVTRQLYEPLVMQLIHWLTNNKKFESQDTVALLEAILDGI-------------VDPVDSTL-RDFCGRCVQEFLKWSIKQTTPQQQEKSPVNS--KSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEGSLVEQFVFEALVTYMESLALAHEDEKSLGTVQQCCDAIDHLRRIIEK-KHVSLNKAKKRRLPQGFPPLTSLCLLDLVEWLLAHCGRPQTECRHKSMELFYKFVPLLPGNKSPSLWLKDLIKKKGISFLINTFEGGASSSDQPAGILAQPTLVYLQGPISLRGVLQWLDLLLAALECYNTF 1269
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Mtor (mechanistic target of rapamycin kinase [Source:MGI Symbol;Acc:MGI:1928394]) HSP 1 Score: 159.073 bits (401), Expect = 9.290e-38 Identity = 143/578 (24.74%), Postives = 260/578 (44.98%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLF--EADIKDNFR---------EDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFS-PWLAKYN-FRD-------------SYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNF--DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ + +N + S + + +M+ + + EE S+L+ E ++K F E G TL + F++ R + + W K + N+KD + W Y+ FR Y P ++ +D L +PG Y+ +P I+I + P +Q++ SKQ P+K+ ++G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ D ++ QK E ++ ++N D L K S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 1932 IDTWLQV--IPQLIARIDTPRPLVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNM-----------------------CEHSNTLVQQAMMVSEELIRVAILWHEMWHEGL------------EEASRLYFGERNVKGMFEVLEPLHAMMERGPQ--TLKETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQLPQLTSLELQYVSPKLLMCRDLELAVPGTYD--PNQPI----IRIQSIAPSLQVITSKQRPRKLTLMGSNGHEFVFLLKGHEDLRQDERVMQLFGLVNTLLAND---PTSLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDY----------DHLTLMQKVEVFEHAVNNTAGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRTTCHTVMEVLREHKDSVMAVLEAFVYDPLLNWRLMDTNTKGNKRSRTR 2445
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202]) HSP 1 Score: 143.28 bits (360), Expect = 5.900e-33 Identity = 94/319 (29.47%), Postives = 164/319 (51.41%), Query Frame = 2
Query: 10907 GQYNN-ITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSE--FYTQYFPNTAAYTKSWEKSDVV---STNQKFEENQNLISNFDLLRKSFMTISKCHESF------YRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
G+Y N +T + F + F+L G+ + PK I +G + + LVK +DLRQD ++Q+F + N ++ ++ T++ K I TY V+P+S+ G+LEW TV + E+ V+SE + +Y PN + + +K V S +K++ + NF+ + + F C E F + R+ + + A + Y+LG+GDRH++N LINE + +++ ID G AF I LP PE +PFRL+ +V+ + +GV G+F + + + + Q T+++I+ V L + + DW
Sbjct: 2682 GEYENLVTIKSFKTE----FRLAGGLNL------PKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRN---TETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYL--------------VNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYF-----CMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDW 2967
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Atm (ataxia telangiectasia mutated [Source:MGI Symbol;Acc:MGI:107202]) HSP 1 Score: 143.28 bits (360), Expect = 6.001e-33 Identity = 94/319 (29.47%), Postives = 164/319 (51.41%), Query Frame = 2
Query: 10907 GQYNN-ITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSE--FYTQYFPNTAAYTKSWEKSDVV---STNQKFEENQNLISNFDLLRKSFMTISKCHESF------YRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
G+Y N +T + F + F+L G+ + PK I +G + + LVK +DLRQD ++Q+F + N ++ ++ T++ K I TY V+P+S+ G+LEW TV + E+ V+SE + +Y PN + + +K V S +K++ + NF+ + + F C E F + R+ + + A + Y+LG+GDRH++N LINE + +++ ID G AF I LP PE +PFRL+ +V+ + +GV G+F + + + + Q T+++I+ V L + + DW
Sbjct: 2685 GEYENLVTIKSFKTE----FRLAGGLNL------PKIIDCVGSDGKERRQLVKGRDDLRQDAVMQQVFQMCNTLLQRN---TETRKRKLTICTYKVVPLSQRSGVLEWCTGTVPIGEYL--------------VNSEDGAHRRYRPNDFSANQCQKKMMEVQKKSFEEKYDTFMTICQNFEPVFRYF-----CMEKFLDPAVWFEKRLAYTRSVATSSIVGYILGLGDRHVQNILINEQSAELVHIDLGVAFEQGKI-LPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQETLLTIVEVLLYDPLFDW 2970
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Atr (ataxia telangiectasia and Rad3 related [Source:MGI Symbol;Acc:MGI:108028]) HSP 1 Score: 135.191 bits (339), Expect = 1.970e-30 Identity = 84/300 (28.00%), Postives = 150/300 (50.00%), Query Frame = 2
Query: 10934 PFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHR 11833
PFP + + ++I+ S Q PKKI + G + + Y + K +DLR+D R+ + +++N + KD +S + I+TY VIP++ G++EW++NT L K K++ Y+ K E P +AA +S K + L + + + F+ S+Y R + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PE++PFRLT +MV + P G G+F + + L + ++ +MS++ FL + +++W +
Sbjct: 2276 PFPGHWAYLAGFDDVVEILSSLQKPKKISLKGSDGKFYIMMCKPKDDLRKDCRLMEFNSLINKSLRKD---AESRRRELHIRTYAVIPLNDECGIIEWVNNTAGLRPILTKIYKEKGVYMTGK---ELRQCMLPKSAA----------LSEKLKVFQELLLPRHPPVFHEWFLRTFPDPTSWYSSRSAYCRSTAVMSMVGYILGLGDRHGENILFDSFTGECVHVDFNCLFNKGETF-EVPEIVPFRLTHNMVNGMGPMGTEGLFRRACEVTLRLMRDQREPLMSVLKTFLHDPLVEWSK 2558
BLAST of DNA-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P97313|PRKDC_MOUSE (DNA-dependent protein kinase catalytic subunit OS=Mus musculus OX=10090 GN=Prkdc PE=1 SV=3) HSP 1 Score: 572.392 bits (1474), Expect = 5.192e-162 Identity = 647/2642 (24.49%), Postives = 1154/2642 (43.68%), Query Frame = 2
Query: 4820 NWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNIC----ENNF--IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDR----NFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL--------IGELSKICSLILYCKSDDSTNKLI--YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDS----------------DSFLQHDGRCLMIINIPYDIVNDHPCMDTFICL-HHQMKNV--GIISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK--MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSS---EKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLT----------------------ASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREK-AVXXXXXXXXXXXIEKNIK-------NSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIP-------YLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKAD-CFGXXXXXXXXXXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKS-------------VVNSKLRTLVFEKNVDEGHT--ISELDELV-KRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQK-CDM----PIDYISKLKGNQ-GDLEKESLEFWENLLFYRTVYLKK-----------GMMKFPFLAEAITTEISD---------------LQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAP-EILIGLTNSVKLLLK-----FPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQ--SEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSE-------SDGNKKELSAALVVVSDFYDAQIRQFENDGPSR--------PDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEF-KNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY---KKVSSEFYTQYF------PNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMK---------NFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
NW + D S++ P+ + + LL +M+ IDS + ++F IF + +LL+ T L + K + I + F + EGS +EN+K ++ NF S + D Y++ + L++ ++ ++ I CRE H E+ + T + + + ++ LL + N+ F+++ ++ CD+ L FF + ++ +K + F NE I K+++ +Y+ L +D V +E K+ + E +++ +L D T ++ Q++ R + A+NC S++ ++ KFY L KP +F ++I FP E+ + ++ K+ + KE + S Y S +L+DSSL+ ++ + + S V S S DS Q D I+ + D +N H CM I L H +NV E + D+P WMK HD ++I+ F+ KL+IN +F+PYA W+ L++ + + I+ + ++ I+ W+ + V K + N L+ +L ++ + ++ R N+E+ +L+ WKE + IPY+ IF+ + + N G+++L V+ N + T + + LV + K V+ A E+ G++L+ I + +E V E+ + + + + F+ CL I K + R ++ L +L LE++ C + E L+ QL + + ++++ + + ++ + + + +N VV+ P + + + D S E +F + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMT PD++ PIF+ H S F+ T S +++QT L + P ++R+ +D PT ++ + + FDW+ +S + + + + S + + + T + + + D+ NQ ++ T Q + + K+ REK ++ K L +QK+EK+IK ++ V LYR+Y G LP+I+IQ+ I PLQ +AQ + +K LF L++G+LKE F + QNL Q F+ L T + +S +I+ + + L+P AS G LA++ + ++ + PP K+++ G + +P L KLY+ +++ + +L ++++ ++D C L + E + +EL S +D L KW EL C +S + +++K V+ SKL+ L+ EG+ ++ +DE + K Q ++ EL E+SL YI+++D ++A + + + +YS L + LQS+ L EI +FL + K D+ P+ + K ++ D+ + + W++++ R +L K M E+I E+ + ++M+ I++ + S + LK K SK + +H S + H S ++P E ++ + ++ LL + + N +I S + + LG + + LS S+ E +NSIL L + T +++I GL ++F+ +K + E E + A + + F D Q+R+ E + P L+ VE L ++KL A+ KFPRLLQII Q++ + N +T SSIP W +I W+ M+ LD + V+ + IAD+YP A+ YPF++ Y TS + F+ +I L + +++H F AL Q+ P+ + W+ + D N + ++NI Y+ MY +G+L G F+ F + F + +F G+ + T+ + F +I + ++K K S+ NLK++SPW++++ + K+ LEIPGQY+ ++P PE H++I + +++M S + PK+I+I G +E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ L +TY V+P++ LGL+EWI+NT+TL + M EE+ K Y + + AY + +++ T F ++ + DLL+++F+ +S E+F LR +F +A+ +H+LLGIGDRHL NF++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT V + P G+ + + L + M +F+ DW M R I+ + Q +I + RKL +P ++ +EL + + S+ F+ N ++++ E+ +Q K LV AT+ L RTW+G+EP
Sbjct: 1622 NWRKCD--SWWAPDSAPESKTTVLSLLAKMLQIDSALSFDTNHSSFSEIFTTYASLLADTKLGLHLKGQAIILLPFF---TSLREGS----LENLKHILEKLIVCNFPMKSDEFPPDSLKYNNYVDCMKKFLDALEL-----SQSPMLFQLMTDILCREQRHIMEELFQTTFKRIARQSPCVTQLNLLESVYTMFRKADLPSNVTRQAFVDRSLLTLLWHCDLDTLKEFFSRIVVDAIDVLK-SRFTKLNEFTFDTQITKKMCYYKMLAVMYSRL----LKDDVHSKEAKINQAFHGSRVAEGNELTKTLLKLCHDAFTENMVGESQLLEKRRLYHCAAYNCAISLISCVFNELKFYQGFLFN-EKPEKNLFIFENLIDLKRCYTFPIEVEVPMERKKKYIEIRKEARDAANGASGSPHYM-----SSLSYLTDSSLSEEMSQFD--FSTGVQSYSYSSQDRKPTTGHFQRREHQDSMTQDD-----IMELEMDELNQHECMAPMIALIKHMQRNVIAPKGEEGSIPKDLPPWMKFLHDKLGNASVSLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAVCENNREGIHYMMVEIVATILSWTGL-ATPTGVPKDEVLANRLLRFLMKHVFHPKRAVFRHNLEIIKTLVECWKECLSIPYRLIFEKFSHKDPNSKDNSVGIQLLGIVIANNLPPYDPNCDITSAMYFEALVNNMSFVKYKEVYAAAAEVLGLILQYITERKHVIAELVCEL---VIKQLKQHQNTMEDKFIVCLNKIAKGFPPLADRFLNALFFLLPKFHGVMKTLCLEVVLC---RAEEITGLYLQLKSKDFLQVMRHRDDERQKVCLDIVYKMVAKLKPIELRELLNP-VVEFVSHPSPTCREQMYNILMWIHDNYRDQESQNDEDSQEIF-KLAKDVLIQGLIDENVGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTRMSPDYLNPIFE-HPLSECEFQEYTIDPDWRFRSTVLTPMFIETQASPSILHTQTQEGPLSDQRQKPGQVRATQQQYD---FTPTQASVERSS--FDWLTGSSIDLLADHTVFSSETLSSSLLFSHKR----TEKSQRMSCKSVGPDFGTKKLGLPD-DEVDNQVKSGTPSQADILRLRRRFLKD------REKLSLLYAKRGLMEQKLEKDIKSEFKMKQDAQVVLYRSYRHGDLPDIQIQHSGLITPLQAVAQKDPIIAKQLFSSLFSGILKEMNKFKTTSEKNIITQNLLQDFNRFLNTTFLFFPPFVSCIQEISCQHPDFLTLDP-----ASVRVG--CLASLQQPGGIRLLEEALLRLMPKEPPTKRVR------GKTCLPPDVLRWMELAKLYR-SIGEYDVLRGIFSSELGTTQDTQNALLAEARSDYCQAAKLYDEALNKLEWVDGEPTEAEKEFWELAS------LDCYNNLSKWKELE---YCSTVNIVSENSLDLSKMWSEPFYQETYLPYVIRSKLKLLL----QGEGNQSLLTFVDEAMNKELQKTV--LELQYSQELSLLYILQDDIDRATYYIKNGIQIFMQ---NYSSIDVLLYRSRLAKLQSVQTLAEIEEFLSFICKHGDLSSLGPLRRLLKTWTSRYPDVVTDPMHIWDDIITNRCFFLSKIEERLTAPSGDHSMSVDEDEESIDREVYEPKEDVRCMLQSCRFTMKMKMIESAWKQSNFSLSMKLLKEM-------HKESKTREIWRVQWLHSYSQLNHCR--SHTQSPREQVLNMLKTITLLDESDISNYLNKNIQASCDQSILLGTTCRIMADALSREPACLSDLEENKVNSILTLSGSNAENT-ETVITGLYQRAFHHLSKAVQSAEEETQLSCWGHEAAAERAHAYMTLVGFCDQQLRKVEESASQKTSAEMEAYPALV---VEKMLRALKLNSSEARLKFPRLLQIIEQYSEETL--NIMTKEISSIPCWQFIGWISHMMALLDKEEAIAVQHTVEEIADNYPQAIIYPFIISSESYSFKNTSSGHNNKAFVERIKSKLDHGEVIHSFINALDQLSNPDLLFKDWVSDTKDELGKNPVN---KKNIEKLYERMY-AALGDLRAPGLGPFRRRFIQAFGKEFVKSFGNGGSKLLTMKVDDFCKITGSLLVRMK----KDSKLPGNLKEYSPWMSEFKAQ--------FLKNELEIPGQYDG-KSKPLPEYHVRISGFDERVKVMLSLRKPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQIFEVMNAILSQDAACSQRNMQL---RTYRVVPMTSRLGLIEWIENTMTLKDLLLSNMSQEEKVANNSDPKAPIRDYKDWLMKVSGKSDAGAYVLMYSRANRTETVVAFRRRESQVPP-DLLKRAFVKMSTSPEAFLALRSHFASSHALLCISHWLLGIGDRHLNNFMVAMETGSVIGIDFGHAFGSATQFLPVPELMPFRLTRQFVSLMLPMKETGLMCTVMVHALRAFRSCAGLLTDTMEIFVKEPSFDWKSFEQTMLRKGGSWIQEINVTEKNWYPQHKIRYAKRKLAGANPAVITCDELYLGHEASSAFRSYTAVARGNRDYNIRAQEPESGLSEETQVKCLVDQATDPNILGRTWEGWEP 4126 HSP 2 Score: 213.386 bits (542), Expect = 3.203e-53 Identity = 280/1273 (22.00%), Postives = 545/1273 (42.81%), Query Frame = 2
Query: 335 IENFCDFIINLVKF-------AKEKLLPFCGLIKNYLMNIVKSKKSSAKMKELSIKSLQDILTLTGNNNF--EMNIGVCLSDLFSQLQNKSS--TTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMD-SGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV--PPDFSIIQD---FSLNISDFEYSINTDSNETDLIKSYAAL-STRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPH--MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNK---LEKLQNRLIRILGKMGINYSRYLIRDNS-RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENI-KFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIF-AMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQ---SFCWL-LSMNLIDAYNYF 3982
IE+F D +KF +K++ + IKN + V +K +AK K ++ L +L + + E IG + + +L +KS TVL + EL+G + ++P+ ++S + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ K + R+A + L LT H + + + +F + K +H NV LK +A + L+ +L QI F + + +Y QF ++ S +K L I+G G C V+ K+ + +Y + + + +L D + +P + + IA +L+ L + + P ++ + F ++SP++ ++F A+ + H + I +V+Q +I CS PV D D S + + + T + DL + DF+ L N + L++D F++ KI+++LDL + + V ++ +DP + P DF +NL + + + + + W L+ +S LPL+SGFYK++ +K +F+ I+ + K + D A+F + K+ Y DELL +CLT +++ P I ++ + P LQMA +LG ++PL + L L+ W + + K ILP L S +S + + L A K +R + + L+ + N+S ++ LE+++ ++++ILG +G ++ L+ S + W+ E + + +PF+++KP I L+ + ++ LAL+++ Q K A E+LHS+++ +LG+ AT + + + + + + F + ++LA D+++V++ L+ L+MQ+ +W + ++ +++ D + +DP + RD G+ + FLK S + VN K +R+Y L + + +KRLGA FN I+ + + L+E +F A++ Y+ E++K LGT+ Q A ++ K ++ +K R +P P T+ + + WLL + + R ++L + + +P+ + K L+ K + ++ FE P+ + A + L+ + WL L + ++ YN F
Sbjct: 75 IEDFRDCREEALKFLCVFLEKIDQKVMHYSLDIKNTCTS-VYTKDRTAKCKIPALDLLIKLLQILRSTRLMDEFKIGELFNKFYGELASKSKLPDTVLEKVYELLGVLGEVHPSEMINHSENLFRAFLGELKTQMTSTVREPKFPVLAGCLKGLSSLLCNFTKSMEE--DPQTSKEIFGFTFKAIRPQIEMKRYAVPLAGLRLLTLHASQFTACLLDNYITLFEVLSKWCSHTNVELKKAAHSALESFLR------QISFTVAEDAELHKSRLKYFMEQFYGIIRNTDS-----NNKELAIAIRGYGLFAGPCKVINAKD-VDFMYVELIQRCKQMFLTHADASEDHVYQMPSF-LQSIASVLLYLDTVPEVYT----------PVLEHLMVVQIDSFPQYSPKMQLVCCKAIIKLFLALSEKGPVH----WNCISAVVHQGLIRICSKPVVLQKDVESRSDNRSASEEVRTGRWKVPTYKDYVDLFQHLLGCDQMEDFILGDETFLFVNSSLKSLNHLLYDEFIRSVLKIVEKLDLTLEKQTVGEQEDGSTADVWVIPTSDPAANLHPAKPSDFSALINLVEFCREILPRKHVGFFEPWVYSFAYELILQSTRLPLISGFYKLLSIAVKNARKIKYFEGISPKSLKHSPEDTEKYSCFALFAKFGKEVSV---KMKQYKDELLASCLTFVLSLPHDIIELDVRAYVP-------ALQMAFKLGLSHMPLAEIGLHALKEWSVHIDKSILQPYYKDILPCLDGYLNTSTLSDETKSHWGLSALSR-AAQKGFNRHVVKHLKRTR-----------------NSSPDEALSLEEIRIKVVQILGSLGGQINKSLVTATSGERMKKYVAWDA--ERRLSFAVPFREMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVMFMLGR-ATQMPEGQGLPPMYQLYKHTFPVLLQLACDVDQVTRQLYEPLVMQLIHWLTNNKKFESQDTVALLEAILDGI-------------VDPVDSTL-RDFCGRCVQEFLKWSIKQTTPQQQEKSPVNS--KSLFKRLYSLALHPNAFKRLGAALAFNHIYKEFREEGSLVEQFVFEALVTYMESLALAHEDEKSLGTVQQCCDAIDHLRRIIEK-KHVSLNKAKKRRLPQGFPPLTSLCLLDLVEWLLAHCGRPQTECRHKSMELFYKFVPLLPGNKSPSLWLKDLIKKKGISFLINTFEGGASSSDQPAGILAQPTLVYLQGPISLRGVLQWLDLLLAALECYNTF 1269
BLAST of DNA-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|Q8WN22|PRKDC_CANLF (DNA-dependent protein kinase catalytic subunit OS=Canis lupus familiaris OX=9615 GN=PRKDC PE=2 SV=1) HSP 1 Score: 539.65 bits (1389), Expect = 4.806e-152 Identity = 629/2634 (23.88%), Postives = 1149/2634 (43.62%), Query Frame = 2
Query: 4820 NWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENN------FIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENI-KTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKA---YENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL--------IGELSKICSLILYCKSDDSTNKLIY--QMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDS-------FLQHDGRCLMI----INIPYDIVNDHPCMDTFICLHHQMKNVGIIS--EVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKS-------DFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRD-SNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSI----------------KSQKSFL-----NLSTSVMHIENEDKASNQQ---ENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPY--LMKLYKVXXX----XXXXXXXXXXXQLSSSKNLVEK---FKEALKADCFGXXXXXXXXXXXXXXEASVD-ENNEFEYELLSVSQNGLIDSLKKLCKWTELT------------KFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELV-KRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQK-----CDMPIDYISKLKGNQ-GDLEKESLEFWENLLFYRTVYLKK---------GMMKFPFLAEAITTEISDLQMQFIDAC-IIHN-------------RMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYL------LSLGDCYWTLGNVLSLHWQ--SEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSE-------SDGNKKELSAALVVVSDFYDAQIRQFENDGP--------SRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY---KKVSSEFYTQYFP------NTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWF------------KCMKNFQSEDA--ETSQTKKLVSMATNSGFLARTWQGFEP 12088
NW + D S++ + + + LL +++ IDS++ N +F + +LL+ +NL + + + + F T G + + +E++ + NF S++ Y++ + L++ ++ ++ I CRE H E+ + T + + + + LAL E ++ K N+ F+++ ++ C + L FFG + + ++ +K + F NE I K++ +Y+ L ++D V +E K+ I E +++ ++ D T + Q++ R + A+NC SV+ ++ KFY L KP + ++I FP E+ + ++ K+ + KE ++ SD P + S +L+DSSL+ ++ + + S V S S F + + + M+ + + D +N H CM T L M+ I+S E + ++P WMK HD ++I+ F+ KL+IN +F+PYA +W+ L++ ++ + I+ V ++ ++ W+ + V K + N L+++L E+ + ++ R N+E+ +L+ WK+ + +PY+ IF+ + + N G+++L V+ N + + + LV + K V+ A E+ G+ L+ I ++ E +LE + +E V+ + K F+ CL + KN + R ++ + +L LE++ C + +N +LEL ++ + + ++++ + + ++ + + + +N+ VV+ P + + + D S+ D + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++AT+ +LEMTS PD+ P+F+ H S F+ T + L P F+ Q +S + Q+ +P + +Q + A+ Q+ + + ++ SS P VD ++S KSQ++ L + + + DK N+ +N+TE + + + K L Y R K + +QK + + K ++ V LYR+Y G LP+I+I+ S + PLQ +AQ + +K LF L++G++KE + + Q L Q F + L + +S +I+ + ++L+P + + S + + LLE+ L+ HL + PPAK+ K ++ + L KLY+ + + +Q++ S E + EA K +L E VD E E E + ++ +D +L +W L LN M E + + ++ SKL+ L+ + D+ ++ +DE V K Q ++ EL E+SL YI+++D ++A+ + E + +YS L + LQS+ + EI +F+ + + P+ + K N+ D + + W++++ R +L K G E +++ ++Q Q + C +I N R FS ++ + K ++ W +K+ VH + H + +IL L LL +T +S L + LG Y + N L +E E IL+L + + + +I L ++F+ ++ + E G L+ A + ++DF D Q+R+ E + P L+ V++ L ++KL A+ KFPRLLQII + + + +T SS P W +I W+ M+ LD + V+ + IAD+YP A+ YPF++ Y TS + F+ +I L ++ F +AL Q+ PE + W D DM + + + S++NI Y+ MY +G+L G F+ F ++F + +F + G+ + + F I + + ++ T NLK+ SPW++ + ++ LEIPGQY+ +P PE H +I + I++M S + PK+III G +E+ Y LVK GEDLRQD RIEQ+F VMN ++S+D ++ L KTY+VIP++ LGL+EWI+NT+TL +F M EE+ Y K Y + + AY ++ + T F ++ + DLL+++F+ +S +F LR +F +A+ +H++LGIGDRHL NF+++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT + + P G+ + + L + + M VF+ DW +M + I+ + +++I+ + RKL +P ++ +EL + + K+ F ++ Q E+ E +Q K L+ AT+ L RTW G+EP
Sbjct: 1638 NWKKWD--SWWAKDSAPESKTAVLTLLAKILQIDSSVSFNTNHSAFPEVFTTYTSLLADSNLGLHLMGQAVILLPFF----TNLTGGNLEDLEHVLEKLIVSNFPMKSEEFPVGTLRYSNYVDCMKKFLDALEL-----SQSPVLLQLMAEILCREQQHVMEELFQSTFKKIARKSSC---VTQLALLESVYRMFKRDDLLSNVTRQAFVDRSLLTLLWHCGLNALREFFGKIVVETIDVLK-SRFTKLNESTFDTQITKKMGFYKMLDVMYSRL----SKDDVHSKESKINQVFHGSCITEGNELTKTLIKLCYDAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFTELKFYQGFLFS-EKPEKNLLILENLIDLKRCYTFPIEVEVPMERRKKYIEIRKEAR--EAVNGDSDG----PHYLSSLSYLADSSLSEEMSQFD--FSTGVQSYSYGSQDPKSTHGHFRRREHKDPMVQDAVLELEMDELNQHECMATMTALIKHMQRNQILSKDEGSVPRNLPPWMKFLHDKLGNPSVSLNIRLFLAKLVINTEEVFRPYAKYWLSPLLQLVVSENNGGEGIHYMVVEIVVTVLSWTGLATPVG-VPKDEVLANRLLHFLMEHVFHQKRAVFRHNLEIIKTLVECWKDCLSVPYRLIFEKFSSKDPNSKDNSVGIQLLGIVMANNLPPYDPKCGIERIKYFEALVSNMSFVKYKEVYAAAAEVLGLTLRYI-----TERENILE-----NVVYELVIKQLKQHQNTMEDKFIVCLNKVVKNFPPLADRFMNAVFFLLPKFHGVMKTLCLEVVLCRAEEITNIYLELKSK----DFIQVMRHRDDERQKVCLDIIYKMMAKLKPVELRDLLNS-VVEFISHPSPVCREQMYNILMWIHDNYRDPESQADDDSREVFKLAKDVLIQGLIDENAGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATDFLLEMTSLSPDYANPVFE-HPLSECEFQEYTIDSDWRFRSTVLTPMFIET-QASQSTLQTRTQERSLPAQGVMARQIR-------ATQQQYDFTPTQTADGRSSFNWLTGSSIDPLVDYTVSSSDSSSSSLLFAQKRNEKSQRAPLKSVGPDFGEKKLGLPG-DKVDNKAKGIDNRTEILRLRRRFIKDQEK-LSLIYAR-KGIAEQKREKEIKSELKMKHDAQVILYRSYRQGDLPDIQIKYSSLVTPLQAVAQRDPVVAKQLFGSLFSGIIKEMDKYKTMSEKNNITQKLLQDFSHFLNSTFSFFPPFVSCIQEISCQHTDLLSLDPGSIRASCLASLQQPVGVRLLEEALL-HLGPQE------PPAKQFK-GRMRVSPDVVRWMELAKLYRSIGEYDILRGIFSSEIGTKQITQSAIFAEARSDYSEAAK-----------QYNEALNKEEWVDGEPTEAEKDFWELAS---LDCYNQLAEWKSLAYCSIVSVDNENPPDLNKMWSEPFYRETY--LPYMIRSKLK-LLLQGEADQS-LLTFIDEAVNKDLQKAL--IELHYSQELSLLYILQDDIDRAKYYIENCIQIFMQ---NYSSIDVLLHRSRLTKLQSVQTMIEIQEFISFISRQGNLSSQAPLKRLLKSWTNRYPDARMDPVHIWDDIITNRCFFLSKIEEKLTLPLGDHSLSMDEERDSSDKMEVQEQGEEVCSLIKNCMFSMKMKMVESARKQHNFSLAMKLLKELRRESK-TRDDWQVKW--VHTYCRLSHSRIQGQSCLQQILSALKTVS--LLAGESTSSYFSKNVLAFHDQNILLGTTYSIIANALRREPACLAEIEESRARRILDLSGSSLE-NAEKVIAVLYQRAFHHLSEAVRTAEEEAQPSLRGQGPVASLTDAYMTLADFCDQQLRKEEESASVTESVELQTYPGLV---VDNMLKALKLHSSEARLKFPRLLQIIELYPEETL--SLMTKEISSTPCWQFIGWISHMVALLDQEEAVAVQCTVEEIADNYPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKTKLDLGGVIQDFISALEQLSNPEMLFKDWTD---DMKAELAKNPVSKKNIEKMYERMY-AALGDLRAPGLGAFRRRFIQVFGKEFDKHFGKGGSKLPGMKLRDFGSITDSLFYKMCT---DSKPPGNLKECSPWMSDFKVE--------FLRNELEIPGQYDG-KGKPLPEYHARIAGFDERIKVMASIRKPKRIIIRGRDEKEYPLLVKGGEDLRQDQRIEQLFEVMNVLLSQDTACSQRNMQL---KTYHVIPMTSRLGLIEWIENTLTLKDFLLSNMSREEKAAYTSDPKAPPCEYRDWLAKMSGKYDVGAYMSMFKAASRTETVTSFRRRESRVPA-DLLKRAFLKMSTGPAAFLALRSHFASSHALMCISHWILGIGDRHLNNFMVSMETGGLIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEAGVVYSIMVHALRAFRSHSDLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVTEKNWYPRQKIHYAKRKLAGANPAVITCDELFLGHEKALAFGDYVAVARGSKDHNIRAQQPENGLSEEAQVKCLIDQATDPNILGRTWIGWEP 4142 HSP 2 Score: 220.32 bits (560), Expect = 2.722e-55 Identity = 306/1314 (23.29%), Postives = 559/1314 (42.54%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQ----KEINNSKTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMDSGY-RFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQ---EQIRSV------LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV---------PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAAL-STRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVN-----NEKIN------TDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKIC----NYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAF------PHMGSWVKLILPSYRTLLLFSPISSDVE--YDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSY---IFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRI---VPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFEST--------------ELFKI--PPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYF-TKGVSNLFTAVNNFL 4027
E F+ ++ +K+ P+ IK + V +K +AK K +L IK LQ + + + F +IG + + +L + K TVL + EL+G + ++P+ + S L L+ I K +++GC +GL F K++ E ++ I+ LK + R+A + L T H + + + +F + K +H NV +K +A + L+ +L+ Q+ F + + +Y QF ++ M S K L I+G G C V+ K+ ++++ E + Q QI +V +P + + IA +L+ L + + +L++ ++ + F ++SP++ ++F A L V + I +V+Q +I CS PV P ++ S + ++ + T + DL +S + D L A L N + L++D F+K KII++LDL + +V NE +DP + PKDF F+NL + + + + + W L+ +S LPL+SGFYK++ ++ +F E + KD Y L +++ Y DELL +CLT +++ P I IE + + LQMA +LG Y PL + L+ LE W PH K ILPS L S +S + + ++V+ A++G ++ L+ ++ + I+ N +L+ LE+++ R++++LG +G ++ L+ S + W++ E + + +PF ++KP I L+ + ++ LAL+++ Q K A E+LHS+++ LGK AT + + F P + F ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD G+ + FLK S + VN K +R+Y + + +KRLGA FN+I+ + + L+E +F + +E L+ D K LGTI Q A ++ + L V K R PPS + ++ ++WLL + + R I+L + + +P+ + K +L K ++ FE LF + P S A+ WM+ L A+++ + + + A + T+ S+L+ AV FL
Sbjct: 93 EEVLKFLYIFLEKIGQKITPYSLDIKTTCTS-VYTKDKAAKCKIPALDLLIKLLQTLRSSRLMDEF--SIGELFNKFYGELALKTKIQDTVLEKIYELLGVLAEVHPSEMINNSEKLFRAFLGELKIQMTSAIREPKLPVLAGCLKGLSSLMCNFTKSMEE--DPQTSREIFDFALKAIRPQIDLKRYAVPLAGLCLFTLHASQFSTCLLDNYVSLFEVLSKWCSHTNVEMKKAAHSALESFLK------QVSFMVAKDAEMHKSKLQYFMEQFYGIIRNMDS-----NSKDLSIAIRGYGLFAGPCKVINAKDV---------DFMYIELIQRCKQLFLTQIDTVDDHVYHMPSF-LQSIASVLLYLDRVPEVYTP-----VLEH-----LMVAQIDSFPQYSPKMQSVCCKALVKVFLA----LGGKGPVLWNCISTVVHQGLIRICSKPVILQKGVESEPEEYRA----SGEVRTGKWKVPTYKDYLDLFRSLLSCDQMMDSLLADEAFLFVNSSLQNLNRLLYDEFVKSVLKIIEKLDLTLEKRNVGEHEDENEATGVWVIPTSDPAANLHPAKPKDFSAFINLVEFCRDILPEKHIEFFEPWVYSFAYELILQSTRLPLISGFYKLLSVAVRNAKKIKYF----EGVGMKSQTQAPKDPEKYSCFALFAKFGKEVTVKMKQYKDELLASCLTFILSLPHDI-IELD-----IRAYIPALQMAFKLGLSYTPLAEVGLNALEEWSVCICKHIIQPH----YKDILPSLDGYLKTSALSDETKNSWEVSAPS----QAAQKGFNQV--VLKHLKKTKN----------ISSNEALS-LEEIRIRVVQMLGFLGGQINKNLLTATSSDEMMKKCVAWDR--EKRLSFAVPFIEMKPVIYLDVFLPRVTELALSASDRQTKVAACELLHSMVMFTLGK-ATQMPECGQ-GFPPMYQLYKRTFPALLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGI-------------VDPVDSTL-RDFCGRCIREFLKWSIKQTTPQQQEKSPVN--TKSLFKRLYSFALHPNAFKRLGASLAFNNIYREFREEESLVEQFVFEALVTYLESLALAHTDEKPLGTIRQCCDAIDHLRHIIEKKHVSLNKVKKRRRPRGFPPSASLCLLDM-VQWLLAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLKDILKNKDTSFLINTFEGGGGSCDRPSGILVQPTLFHLQGPFSLRAALQWMDMLLAALECYNTFIEEKTLKAPDVLGTETQSSLWKAVAFFL 1310
BLAST of DNA-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|Q9DEI1|PRKDC_XENLA (DNA-dependent protein kinase catalytic subunit OS=Xenopus laevis OX=8355 GN=prkdc PE=2 SV=1) HSP 1 Score: 385.571 bits (989), Expect = 2.622e-105 Identity = 250/825 (30.30%), Postives = 417/825 (50.55%), Query Frame = 2
Query: 9800 LGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKD------SLICGLLNKSFYCFNKIISMYSESDGNK-------KELSAALVVVSDFYDAQIRQFENDGP--SRPD---LIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML------YVADVTSKSN--FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY--KKVSSEFY--------TQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMS-------KQSIETFT-----QKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSED--------------AETSQTKKLVSMATNSGFLARTWQGFEP 12088
LGD Y + + + EP + + ++ D KD +++ GL KS + F + +E + + + + A + + DF D+ +R+ E + R D VE + ++KL A+ KFPR+LQII Q+ + D + ++P W +I W+ QM+ LD S V+ II IA++YP AL YPFM+ + V N ++ +I L + F AL Q+ P Q W ++ ++ S + + N + + Y++MY + GN G F+ F + + D F +G+ + + + F++ + ++K + E NLK++SPW+ S ++P+ + ++ LEIPGQY+ ++P PE H+KI + + +M S + PK+II+ G++E+ Y FLVK GEDLRQD RIEQ+F +MN I+S+D ++ L KTY VIP++ +GL+EW++NT TL EF TM ++E IY K + Y + + + S+ + D +T F E + L+ DLLR++F+ +S E+F LR +F + +A+ +H+++GIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT +V + P G+F + + L + +++ M VF+ LDW + K++++ + Q++I+ + RKL +P + EEL++ + + +K D E +Q + L+ AT+ L R W+G+EP
Sbjct: 3351 LGDTYRIMADAVC----KEP-----DCLYKIEDGKAGKVKDLSESPENVVGGLYRKSLHYFTNAVRKATEEEQSHSTDQIDVRGIIKAYMTLVDFCDSHLRKVEEESAVMDRADYQNFPEIMVEKMIKALKLNSSEARLKFPRMLQIIEQYPSETLDL--MARENCTVPCWQFIGWISQMMAMLDKKESIAVQHIIEEIAENYPQALVYPFMVSGESYNFEDTVVGHKNREYVNRIKSKLDKDNVAQDFIRALEQLSNPPMIFQDWWEDVSNELSKPNVNKNKIKEL---YKEMYTNL-GNPKDHFMGAFRRRFCEKYTKDFDKAFGPEGSKLLNIKCDGFNKTVGPLITKMKEQQ---KEPGNLKEYSPWM-------SEFKPEFL-RNELEIPGQYSG-RSKPMPEYHVKISGFDERVSVMASIRKPKRIIVRGNDEREYPFLVKGGEDLRQDQRIEQLFEIMNIILSQDAACSQRHMQL---KTYQVIPMTTRIGLIEWLENTCTLKEFILNTMTEDEAKIYNSKTTNGPLYHYNAWLDKKEKVGDARQHVTSYTRCDRTNTVASFREREALVPK-DLLRRAFVKMSTTPEAFLSLRSHFARSHALLCVSHWIVGIGDRHLSNFMINMETGGMIGIDFGHAFGTATQFLPVPELMPFRLTRQIVNLMLPMKDSGLFDSVMVHSLRAYRSDPGLLVTTMDVFIKEPSLDWKNLELKQMKKKGEWKKAVDVTSHNWHPQQKIHCAKRKLDGANPCEITCEELRLGHESAPEYKDFIAVARGDKKHNRRTNEPPDGLTEETQVQCLIDQATDPNILGRVWKGWEP 4144 HSP 2 Score: 236.498 bits (602), Expect = 2.876e-60 Identity = 292/1228 (23.78%), Postives = 518/1228 (42.18%), Query Frame = 2
Query: 524 EMNIGVCLSDLFSQLQNKS--STTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEIN----NSKTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMD-SGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVD---NLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSED--------VNNEKIN--TDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATA---KRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT---WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRI---VPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNP-NSFFKALLTAKPLEYITKKFES--------TELFKIP-------PSPVNAIF-WMNTLEASVQSFCWLLSMNLIDAYNYFTK 3988
E IG + + +L KS S TVL + EL+G + + P T+ S L L+ ++N N K +I+GC +GL F K + E ++ I+ +K + R+A + L+ L H + + D Q +F I K H N +K A LD +L+ I + + +H + + QF ++KM S ++K L I+G G C + K + ++Y + + + YL E D E+ +Y + + L S+ ++ + P Y ++ RL V I+ P + + A++ +L V S+I +V+Q +I CS PV ++ S+ E + T + + +D+L + +L+ + KD + L++D MK KII++LDL + +D +NN IN +DP A+ PKDF FVNL + + + + W LV +S LPL+SGFYK++ ++K +F+ + K A D L A+F + S KI + DELL +CLT +++ P I + + + + LQ A +LG PL L+ L+ W P ++ P Y+ ++ P+ Y N E + R SR L + Q+I+Q + + + + + +SL + +NR++RILG +G +R L+ S +++W+ E + +++PFKD+KP I L+ + I+ LAL+++ Q K A E+LHS++ +LGK AT + + P + F + ++LA D++KV++ L+ L+M + +WF+ ++ +++ + +DP + RD GQ + FL+ S + + VN +R+Y L + + +KRLGA FN+I+ + + L+EN +F ++ +E LS D K LGT Q A ++ + L +K RI P T + + WLL + R + L + P ++ + + + ++ +FE T +F IP P ++A+ W++ L A++ + + M + A K
Sbjct: 166 EFKIGEIFNKFYGELATKSKLSDTVLEKVYELLGILGEVQPCEMTYNSEKLFKAFLGELKAQMNSSTRNPKFPVIAGCLKGLSALMINFTKTMEE--DPRTSKEIFDYTVKAISPQVEMKRYAVPSAGLNLLALHASQFSSYLMDDYQSLFEVISKWCGHTNGEMKKLAFAALDSFLKQIAHLVA-----SDAETH-KNKLHFFMEQFYEIIRKMDS-----SNKELSIAIRGYGLFAAPCKAVNAK-NVDLMYIELIQRCKQMYLTEADTEED-------NVYQLPNFLQSVASVI--------LHMDSIPEVYTPILERLLVVQID---SFPQYSLKMQSSCCKAVLKVFLSLAGKGPVLWSLISTVVHQGLIRVCSKPV-----VLAQDGKEGSEAETAAATGEVRAG---KWKVPTYKDYLDLFRNLLRCDQLKDSIFSDEIFSTVNSPLQSLNRLLYDELMKSILKIIEKLDLSLQKQDTGQEDDGGINNLLINATSDPAGNLYATKPKDFTAFVNLVEFCSEILPKEHIEYFESWVYVFGYELVLQSTRLPLISGFYKLLSVVMKNAKKSRYFEGFTSKIYKKAPEDPERLSCFALFAKFGKEVSS---KIRQFKDELLASCLTFVLHLPHDIIMMDIKAY------IPALQTAFKLGLSCPPLADVGLNALQYWSTNIPS-----DILKPYYKDII---PLLDG--YLTNLSSTNESLSTLDMVRISRSLHKGFNK-QLIQQLKRMKTLS--VKEESSLTAV---RNRVVRILGSLGGQINRSLVTAASTEEMIKRHVSWDT--EKRLRFDVPFKDLKPVIYLDMFLPHITELALSTSDRQTKVAACELLHSIVAFMLGK-ATQMPDDKKTGSSPMYKIYKRTFPVLLRLACDVDKVTEQLYKPLVMSLIHWFTNNKKFESQDTVALLEAILTGI-------------VDPVDSTL-RDFCGQCIQEFLRWSIKQTTPDQQAKSPVN--TTSLFKRLYSLALHPNAFKRLGAALAFNNIYRDFREETALVENFVFEVLVIYMESLALSHADEKSLGTTQQCSDAVDHLKRIIIRKAASLNKATKRRIPRGFPQGNTVCLFDIVL-WLLEQCGRPQTECRHKAMQLFFEFVPLLPGNKPLTAWLDDQVEKEGIIFLINRFEGAGHSDGMHTGIFNIPALHDLHEPFSMHAVLQWLDMLLAALDCYNTFIGMRFLKANTVLGK 1308 HSP 3 Score: 201.06 bits (510), Expect = 1.668e-49 Identity = 300/1376 (21.80%), Postives = 588/1376 (42.73%), Query Frame = 2
Query: 4799 IVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNIC----ENNF--IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIEN-IKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLA----LFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKV--------GLREKKLIGELSKICSLILYCKSDDSTNKLI-YQMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLE-----NILSRNVNSNLMDSDSFLQHD----GRCLM-IINIPYDIVNDHPCMDTFICLHHQMKNVGI---ISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFG-----FIKQLVKILHST-LKTVFGPAFELCGILLKQILKDSDSKSEWVLE-IEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWN---IFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDL-----SSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTA-----------------SKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLAS--TLQFPSQEINEN--------NYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSA-VYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLK 8644
+V + +NW ++D + Y D LT LL +++ IDS++C + F +F + ++L+ L + K++ I + F K G ++N + F NF S + Y++ I L++ ++ ++ I CR+ H E+ + + + + +R + ++ LL +F+ E ++ + +++ ++ C + + +FF + I ++ +K + F E + I K++ Y+ L ++D++ + K EL+K +LI C + N Q++ R + A+NC S++ S+ KFY L K +F ++I FP E+ + ++ K++ + KE + +S EP + S +++DSSL ++ + + S + S ++ + + + G+ ++ D +N H CM L M I + E ++PSWMK H ++I+ FI KLI+N +F+PYA FW+ +++ ++ + I+ V L I+ WSS+ + +K I N L+ +L +N + + ++ R N+E+ ++L WKE + IPY+ I++ + N G+++L L N + + D K G + + L L T K V+ A E+ G++L+ I+++ V + + KE+ + + F+ CL + KN R ++ ++ +L L + LE++ M + + +LF +L + I N + V II +T + + A F C +++ +F ++ + ++ + N + LL G +D + ++ +RNF S LP+ T ER IL L+ S I +L++ATN++LEMTS PD+++ +F+ H S F++ T ++++ RS + + + + Q ++ + NI ++ +F+W+ +S TL S E E+ N ++E + ++P + + ++ L + ++ + S+ + F + + Y ++ + REKA+ KIE+ +K A + LYRNY G+LP+I+I + IAPLQ LAQ + +K LF L++G+L ++ S + L +QF++ L I+ + + ++LNP+ + + S + L +LLEK L+ H+K + PPAKK++
Sbjct: 1640 LVNAVLENWRRLDSWWYKDSPSESKMAVLT--LLAKVLQIDSSVCFDINHSAFAEVFKTYTSILTDQKLGLNLKSQAIIILPFFTKLT----GEKLTELKNTLDQFVASNFPMKSDEFPKGTLKFNNYVDCIKKFLDALEL-----SQSPMLLQLMTEILCRDERHFMEELFQSSFKKVIKRSSCDTQVILLNTLHNMFKSESLMLNG--TLQSLIDRCLLTLLWNCSLDAMISFFTNIISLAMDTLK-SRFTKVPEAAFDSQITKKWGYYKMLEVQYSRL----SKDEIYSTVNNAYHVSSKPEGNELTK--ALIKLCYDTFTENMCGETQLLEKRRQYHCAAYNCAISLISCVFSELKFYQGFLFTEKKEKNLLIFENLIDLQRNYTFPIEVEVPMERKKKYFAIRKEA------RDASSTESDEPSYLSSQSYMADSSLIEEMSQFDFSTGVQSFSYSSQSKMLSQSASRKKEQITEGKTFDDVMEFEMDELNQHECMAAMTGLIKHMNRSEITPKVDEDASPQELPSWMKFLHVKLGNTSTPLNIRLFIAKLIVNTEEVFRPYARFWIGPILQLIVSGNNGGTGIHYMVVETLVTILSWSSI-ATPNGQAKEEILANRLLEFLMKNVFHEKRAVFRHNLEIIKTVLECWKECLSIPYRLIYEGFSGTDPNTKDNSVGIQLLGLALANNFSPL-----DPKCGIDPERYFQSLANNLGLTRFKEVYIAAAEVIGLVLRYIVQNEKRTEAPVFDYVVKELK---RHQTNNKEDKFIMCLNKVVKNFPPFADRFMTIVLFLLPKLHGVLKTQCLEII---MHRAEDIPDLFIELKNKDFCQIMNNRDDERQRVCLDIIYKILSKLTPAELHEFLIPVTAFSSHSFPVC-------RERMYDIFMWIYDNYRDHESQNDSKSVEVFNMAKEGLLQGLVDENTELQLIVRNFWSDETRLPSNTTERMLAILSSLY--SPKI--------EKHYLSLATNLLLEMTSKSPDYIRKMFE-HPLSECKFQDYTVDSSWRFRSSVLTPMFVETQLSQSMQRSRAQGTIEADEPIGGQLRATQQHYQFTPTQNIGGRS-SFNWLTGSSMDTLADYSVESPESLPSALLFVNKRNE-----NVRRVPLKPLGPNFGMRRLGLPGDVTDSKTKSMEDRSDILRLRRRFLKDREKLSLIYARKGTAEQKREKAI----------KIEQKMKQDAQITLYRNYRQGELPDIQISYSNLIAPLQALAQRDPTMAKLLFSSLFSGILTDTA----SDI--SVTDKLLKQFNSFLSNSLSYFPPFIACVQDMCYQHDELLHLNPANISTSCLASLQQPLGILLLEKGLL-HMKVP-----DEPPAKKMR 2931
BLAST of DNA-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|Q8QGX4|PRKDC_CHICK (DNA-dependent protein kinase catalytic subunit OS=Gallus gallus OX=9031 GN=PRKDC PE=2 SV=1) HSP 1 Score: 370.548 bits (950), Expect = 9.426e-101 Identity = 306/1133 (27.01%), Postives = 529/1133 (46.69%), Query Frame = 2
Query: 9026 VVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYSLS-SEADTLM-------LQSLHFLNEICQFLQAVQKCDMPIDYISKLK-------GNQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISD---------------------------LQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYL----LSLGDCYWTLGNVLSLHWQ--SEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFN--------KIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSR---------PDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLY--------VADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWL-DEANDMFSSNSHDSNSRQNIVNK--YQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQL-KTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYK--KVSSEFYTQYFPNTAA-------YTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ------------KRINISHRKLKREDPLLLLYEELQIKYGKSNWF------------KCMKNFQSED--AETSQTKKLVSMATNSGFLARTWQGFEP 12088
++ SKL+ L+ +N + ++ +DE +K Q E+ E+SL YI+++D+++A+ + I G + S S DTL+ LQS+ L EI F+ + K LK D + + + W++++ R +L K KF + E+ + ++++ I++ N S A K + + ++ W ++++ + R H S + PE ++ + ++ LL + +N ++ L LG Y + N LS + + E + ILEL + + + + ++ GL ++F CF+ ++ S+ E K + A + +V F D +R+ E +G P ++ VE + ++KL A+ +FPRLLQII ++ + +T S+P W +I W+ QM+ LD + V+ + I D YP A+ YPF + A F+ I L +V F AL Q+ P + W+ D N++ + R I+ K Y+ MY+ + G++ G ++ F + F D +F + G+ + + + F+EI + ++ KT K E NLK+ SPW+++ FR + ++ LE+PGQY+ +P PE H+KI + I ++ S + PK+I I G +EQ + FLVK GEDLRQD RIEQ+F VMN ++S+D ++ L KTY VIP++ LGL++W++NT TL EF +M +EE Y K Y+ + Y ++ + T F+ ++ + DLLR++F+ +S E+F LR +F+ +A+ +H++LGIGDRHL NF+IN+ TG ++GIDFG+AFG AT FLP+PEL+PFRLT V + P G+ + + L + ++S M VF+ LDW + + T+ + ++++ RKL +P + +EL++ Y K ++ ++ + ED +E +Q + L+ AT+ L R W+G+EP
Sbjct: 3050 IIRSKLKLLLNGEN--DQTLLTFIDEAMKTEQKKAL-IEMHYSQELSLLYILQDDFDRAKYY-------IGNGIQIFMQSYSSIDTLLYQSRMSKLQSVQALTEIQDFINFMTKTSNIASQAKSLKRLLRTWTSRYPDAKMDPMNIWDDIITNRCFFLDKLQEKFLCDKANDSMEVDEESSVGDQMEVDQQDEDIHSMIRSCKFNMKLKMIESARKQNSFSIA-----KKLLKGLRREAKTREDWLVRWNYAYCR--FVH-SCSQSQSCPERVLSVLKTISLLEDTKSDYLNKNIMAFRNQNLLLGTTYHIMANALSQDPKCCEQIEEEKTGKILELSGESSE-SPEKILAGLNKRAFQCFSSAARKSEEEVQSLSMEHVDVKGVIDAYMTLVG-FCDQHLRK-EEEGSLEINAADLQLFPAIV---VEKMIKALKLNSREARLRFPRLLQIIERYPAETL--GLVTRELPSVPCWQFIGWISQMMALLDKDEAVAVQHTVEEIVDTYPQAIIYPFTISSESYCFKDTAAGCRNKEFVASIKNKLDRGGVVQDFIHALEQLSNPVMLFKDWVADVRNELVKTQ------RNKIILKEMYEGMYKNL-GDVKAPGLGWLRKRFVQAFGKDFDSHFGKGGSKLLDMKISDFNEITTALLTKMNKTHK----EPGNLKECSPWMSE--FRAEFL------RNELEVPGQYDG-KGKPLPEYHVKISGFDERIMVLESLRKPKRITIRGSDEQEHPFLVKGGEDLRQDQRIEQLFDVMNIVLSRDAACSQRNMQL---KTYQVIPMTTRLGLIKWLENTCTLKEFLRNSMTEEEDANYNSLKGPRAAYSDWLSKMGGKAQGLSRYNAMYKNASRTETVIAFKSRESSVPE-DLLRRAFVKMSTSPEAFLALRSHFVSSHALMCVSHWILGIGDRHLSNFMINKETGGMVGIDFGHAFGSATQFLPVPELMPFRLTRQFVNLMMPVKEWGLIYSVMVHALRAYRADPDLLISTMDVFVKEPSLDWKNFEQRQLKKGGTWIKEINTAEVNWYPLQKVSYVKRKLTGANPARITCDELRLGYEKLPFYNDFAAVARGSADHNIRAKEPEDRLSEETQVRCLIDQATDPNLLGRVWEGWEP 4132 HSP 2 Score: 231.876 bits (590), Expect = 9.234e-59 Identity = 293/1268 (23.11%), Postives = 532/1268 (41.96%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLLKILHMD-SGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSIN---TDSNETDLIKSYAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEKIN----------TDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINY-LVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPH--MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMG--INYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT-WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDL-SEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAY 3973
E F+ ++ E+ P+ +K ++ V +K+ +AK K EL IK LQ + EM +G + + +L ++K S TVL + EL+G + ++P + S L L+ ++ ++ K I++GC GL F K++ E A++ I+ +K + R+A + L + H A + +F + + H N LK + LD +L+ Q+ + A + + + ++ QF +++M S ++K L I+G G C + P + + +Y + + + YL E E I L Y + L S+ ++ F + P Y V+ L + I PR + + R + L V + I +V+Q +I S P+ FS ++ E S + +S E D + + + +D+L + ++L + K+ + L++D +K KII++LDL + +V+ + N +DP P DFI F+NL + + + + + W + Y L+ S LPL+SGFYK++ +KI +F+ + K + F + K+ Y DELL +CL L++ P I + + + + LQ A +LG P+ LD LE W P M + K +LP L S + + + + ++L A++G K I QR +A S ++DN S LE ++ R+ R+LG +G IN++ ++W+ + + +PF D+KP I L+ + ++ LAL+++ Q K A E+LHS++ +LGK + + + + + IF + ++LA D+++V++ L+ L+MQ+ +WF+ ++ F+++ + +DP + RD GQ + FLK S K +K K +R+Y L + S +KRLGA FNSI+ + + L+E +F + +E L+ D K LGT Q A ++ + K+ ++ R VP P+ + ++ + WLL + R ++L E + +P+S+ +L + + ++ KFE PS I TL + F L M +D +
Sbjct: 76 EEALKFLCVFLERIGERAHPYACSLKQTCIS-VYTKERAAKCKIPALELLIKLLQSLRRSCLME--EMKVGEIFNKFYGELAVRSKISDTVLEKIYELLGVLGEVHPADMINNSEKLFRAYLGELKTQMTSATRVPKLPIVAGCLRGLTALMYNFTKSVDE--DAQTSKEIFDFAVKAIRPQVDQKRYAVHLAGLQLFSWHAAQFGTLLLDSYVMLFETMCRWCGHTNQELKKAGHNALDSFLK----QMSLMVAKD--AELHKSKLKFFMEQFYGIIRRMDS-----SNKELSIAIRGYGLFAAPCKAMHPAD-VDAMYIELLQRCKQMYLTEA--ETIDDHL-----YQLPSFLQSIASVI--------FHLDTIPEVYTPVLEHLVVLQINSFPRYSEKMQLVCCRSIIKVFLALSIKGPVLWNFISTVVHQGLIRVFSKPM--------KFSKDVFGKETSGSEEFPESGEVDTAR-WKVPTYKDYLYLFRSLLSCDTMKESIFEEENFLTGNSPLQSLNRLLYDELIKSILKIIEKLDLTVQKLNVHEQDENETDSAFIGPTSDPASNLQPKKPTDFIAFINLVEFCRDILPDKHVEYFQPWV-YSFGYELIIHSTRLPLISGFYKLLSVTMKIAKKIKYFEGVGPKSLRKATEDPEKSSCFALFAKFGKEVTAKMKQYKDELLASCLNFLLSLPHDIVMLDIKAY------IPALQNAFKLGLSCTPMADLGLDALEDWSAHIPRHIMQPYYKDVLPLLDGYLKNSATTVEPQNNWEVRKLSR--AAQKGFNK----------IVIQRLRKAKTSSLDDNPS---LEAVRTRVARLLGSLGGQINHNLITATSAEEMMKKCVSWDTKNH--LSFAVPFADMKPVIYLDVFLPRVTDLALSASDRQTKIAACELLHSIVAYMLGKASQMPERQQGPPPMHQLYKRIFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVTFLEAILSGI-------------VDPVDSTL-RDFCGQCVREFLKWSI--KQTTPKQQEKSPANTKSLFKRLYSLALHPSAFKRLGAALAFNSIYREFREENSLVEQFVFEALVVFLESLALTHTDEKSLGTTQQCCDAINHLKRIIKH-KAPALNKEGKRRVPRGFPATKSVCLQDVVMWLLVQCGRPQTECRHKAMELFYEFVPLLPGNNSPSSWLADVLKKRDVSFLINKFEGGGSDAKSPS---GILSQPTLRDMQEPFSLLTVMRWMDMF 1258 HSP 3 Score: 145.976 bits (367), Expect = 8.551e-33 Identity = 216/1050 (20.57%), Postives = 442/1050 (42.10%), Query Frame = 2
Query: 4799 IVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENN------FIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDR----NFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNE----RELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKL-----------IGELSKICSLILYCKSDDSTNKLIY-QMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLL----RYNKPLFRHII--YKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLE--------NILSRNVNSNLMDSDSFLQHDGRCLMIIN----IPYDIVNDHPCMDTFICLHHQMKNVGI---ISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKANI------NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTD--NDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNI--PEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFV 7738
+V + NW ++D S++ + + + + LL +++ IDS++ N +FD + +LL+ NL + K + + F + + + ++K D+ NF S + Y++ L++ ++ ++ + CR+ H ED + + + + R +++++ LL + NI+ F+++ ++ C + L FF I Q ++ + + F NE ++ + K++ +Y L ++D V ++ K+ EL+K +LI C + N Q++ R + A+NC +V+ ++ KFY L N +F ++I + YV FP E+ + ++ ++ + KE + + + + EP + + A ++ DSSL+ ++ + + + S++V ++ S F + + M++N + D +N H CM L M+ I + E + D+P WMK H ++I+ FI KLI+N +F+PYA W+ +++ ++ I+ V + ++ W+SV K NI N L+ +L +N + ++ R N+E+ +++ WK + IPY IF+ + + N G+++L VL N + + + LV + K V+ A E+ G+ L+ I + + + V + + + + + F+ CL + KN + R ++ + ++ L +YC LE++ C + E +L+ QL + + ++++ + + ++ ++ + PE K ++ V Q + + + D S+ ++ + LL G ID + ++ +RNF S LP L+R +L NS+ S +++L++ TN +LEMTS PD+ + IF+ H S F + + L P FV
Sbjct: 1617 LVTAVLRNWKRLD--SWWAKDSSPESKMAVLTLLAKVLQIDSSVSFNTSHEAFTAVFDTYTSLLTDQNLGLNLKGHAVIILPFFTNLSGEK-------LHDLKNALDQLVAFNFPMSSDEFPKGTLKHNNYVDCTKKFLDALEL-----SQSPMLLQLMTEVLCRDHRHSMEDLFQASFKRISRRSSTDKQVVLLDTVHKMFQNEDLLSNIVRQAFVDRSLLTLMSHCSLDALREFFCKIIVQAMDTLN-SRFTKSNECVFDTQITKKMGYYKMLEVMYIRL----SKDDVHSKDSKINQAYRGSVSVEGNELTK--ALIKLCYDAFTENMAGENQLLEKRRQYHCAAYNCAIAVISCVFTESKFYQGFLFTEKSEKNLLIFENLIDLKRQYV--FPVEIEVPLERKKRYIAIRKEA------REAWNDGQDEPKYLASASYMMDSSLSEEMSQFDFSTGVQGFSYSSQDVTAS---SAHFRRKETSEYMVLNDEMELEMDELNQHECMAPLTTLIKHMQRNQITPKVEEGVIPVDLPLWMKFLHSKLGNPSVPLNIRLFIAKLIVNTEDVFRPYAKQWLGPMLQLVVSGDNGGEGIHYMVVEIAVTVLSWTSV-----TTPKGNIKDEILANRLLEFLMKNAFHQKRAVFRHNLEIIKTVIECWKNCLSIPYSLIFEKFSSGDPDTKDNSVGIQLLGIVLANNLPPFDLKCEIDRVRYFQALVSNMGLLRYKEVYAAAAEVLGLALQYIAERQNILEDPVYDC---VIKQLKRHQNTQQDKFIICLNKVVKNFPPLADRFMNAVFFLIPKLHGVMKNYC--LEVIMC---RAEEIPDLYLQLKSKDFIQIMKHRDDERQRVCLDIIYKMLSTLKPPELK---ELLPGVTGFISHPSVICRQRMYDILMWIYDNYSDPESQADGDSQEVLSLAKEILLQGLIDENAELQLIVRNFWSDETRLPANILDRMLMLL-------NSLYSAKI---ETQYLSLITNFLLEMTSKSPDYSRKIFE-HPLSECKFHDFVIDSSWRYRSTMLTPMFV 2607 HSP 4 Score: 70.4774 bits (171), Expect = 5.589e-10 Identity = 50/174 (28.74%), Postives = 85/174 (48.85%), Query Frame = 2
Query: 8186 NSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPY--LMKLYK 8701
+ V LYR+Y G LP+I+I++CS IAPLQ LAQ + F+K LF L+ G+ E + + Q L + F++ L T I+ +I+ + + L+ + V + S + + +LLE L+ E PP+K+++ T ++ + L KLY+
Sbjct: 2771 DGQVTLYRSYRVGDLPDIQIEHCSLIAPLQGLAQKDPTFAKQLFSSLFGGIFCEVKKSKIPSEKKAIIQKLLKDFNHFLSTSVSYFPPFIACIQEISYKHRELLELDSANVSTSCLASLQQPVGILLLEHALMA------LSPAEEPPSKRMR-GRTELPPDVVKWLELAKLYR 2937
BLAST of DNA-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P78527|PRKDC_HUMAN (DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3) HSP 1 Score: 368.237 bits (944), Expect = 4.718e-100 Identity = 250/829 (30.16%), Postives = 419/829 (50.54%), Query Frame = 2
Query: 9800 LGDCYWTLGNVLSLHWQSEP------ENKIINSILELIDHTGDYTKDS--LICGLLNKSFYCFNKIISMY-------SESDGNKKELSAALVVVSDFYDAQIRQFENDGP--------SRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY---KKVSSEFYTQYFP------NTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
LG Y + N LS SEP E ILEL +G ++DS +I GL ++F ++ + S S G + A + ++DF D Q+R+ E + + P L+ VE L ++KL A+ KFPRLLQII ++ + + +T SS+P W +I W+ M+ LD + V+ + I D+YP A+ YPF++ Y TS + F+ +I L ++ F AL Q+ PE + W +ND+ + + +++NI Y+ MY +G+ G F+ +F + F + +F + G+ + + + F++I N + L NLK+ SPW++ + ++ LEIPGQY+ +P PE H++I + + +M S + PK+III G +E+ + FLVK GEDLRQD R+EQ+F VMN I+++D ++ +AL ++TY+V+P++ LGL+EW++NTVTL + TM EE+ Y + Y + + AY ++ ++ T F + ++ + DLL+++F+ +S E+F LR +F +A+ +H++LGIGDRHL NF++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT + + P G+ + + L + + + M VF+ DW +M + I+ + +++I + RKL +P ++ +EL + + K+ F+ N ++++ E+ +Q K L+ AT+ L RTW+G+EP
Sbjct: 3330 LGTTYRIIANALS----SEPACLAEIEEDKARRILEL---SGSSSEDSEKVIAGLYQRAFQHLSEAVQAAEEEAQPPSWSCGPAAGVIDAYMTLADFCDQQLRKEEENASVIDSAELQAYPALV---VEKMLKALKLNSNEARLKFPRLLQIIERYPEETL--SLMTKEISSVPCWQFISWISHMVALLDKDQAVAVQHSVEEITDNYPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKSKLDQGGVIQDFINALDQLSNPELLFKDW---SNDVRAELAKTPVNKKNIEKMYERMY-AALGDPKAPGLGAFRRKFIQTFGKEFDKHFGKGGSKLLRMKLSDFNDITNML---LLKMNKDSKPPGNLKECSPWMSDFKVE--------FLRNELEIPGQYDG-RGKPLPEYHVRIAGFDERVTVMASLRRPKRIIIRGHDEREHPFLVKGGEDLRQDQRVEQLFQVMNGILAQDSACSQ--RALQ-LRTYSVVPMTSRLGLIEWLENTVTLKDLLLNTMSQEEKAAYLSDPRAPPCEYKDWLTKMSGKHDVGAYMLMYKGANRTETVTSFRKRESKVPA-DLLKRAFVRMSTSPEAFLALRSHFASSHALICISHWILGIGDRHLNNFMVAMETGGVIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDPGLLTNTMDVFVKEPSFDWKNFEQKMLKKGGSWIQEINVAEKNWYPRQKICYAKRKLAGANPAVITCDELLLGHEKAPAFRDYVAVARGSKDHNIRAQEPESGLSEETQVKCLMDQATDPNILGRTWEGWEP 4126 HSP 2 Score: 238.039 bits (606), Expect = 1.068e-60 Identity = 301/1297 (23.21%), Postives = 569/1297 (43.87%), Query Frame = 2
Query: 338 ENFCDFIINLVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMDSGY-RFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV-----PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSY-AALSTRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK-----------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ-INLECTKVA--DNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERW-IKAFPH-MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMG--INYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT----WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRI---VPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNA---IFWMNTLEASVQSFCWL-LSMNLIDAYNYF-------------TKGVSNLFTAVNNFL 4027
E F+ ++ +K+ P+ IKN + V +K +AK K +L IK LQ + + F+ IG S + +L + K TVL + EL+G + ++P+ + + + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ +LK + R+A + L H + + + +F +LK H NV LK +A + L+ +L+ + + A N + + +Y QF ++ + S +K L I+G G C V+ K+ + +Y + + + +L + D R +P + + +A +L+ L + + +L++ ++ + F ++SP++ ++ R I + L A V + I +V+Q +I CS PV P S S + ++ + T + DL + ++ D + A N + + L++D F+K KI+++LDL + + V ++ +DP + PKDF F+NL + + + + W L+ +S LPL+SGFYK++ ++ +F+ ++ + K + D A+F + K+ Y DELL +CLT L++ P I ++ + P LQMA +LG Y PL + L+ LE W I H M + K ILP L S +S + + + L A++G K+ L+ ++ + S +A+ LE+++ R++++LG +G IN + + + + W++ E + + +PF+++KP I L+ + ++ LAL ++ Q K A E+LHS+++ +LGK AT + E + P + F + ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD G+ + FLK S K I +K K +R+Y L + + +KRLGA FN+I+ + + L+E +F + +E L+ D K LGTI Q A ++ L K R+ PPS + ++ ++WLL + + R I+L + + +PN + K +L + + ++ FE + PS + A + ++ + + CWL L + ++ YN F T+ S+L AV FL
Sbjct: 83 EEILKFLCIFLEKMGQKIAPYSVEIKNTCTS-VYTKDRAAKCKIPALDLLIKLLQTFRSSRLMDEFK--IGELFSKFYGELALKKKIPDTVLEKVYELLGLLGEVHPSEMINNAENLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE--DPQTSREIFNFVLKAIRPQIDLKRYAVPSAGLRLFALHASQFSTCLLDNYVSLFEVLLKWCAHTNVELKKAALSALESFLKQVSNMV----AKN--AEMHKNKLQYFMEQFYGIIRNVDS-----NNKELSIAIRGYGLFAGPCKVINAKD-VDFMYVELIQRCKQMFLTQTDTGDDRVYQMPSF-LQSVASVLLYLDTVPEVYTP-----VLEH-----LVVMQIDSFPQYSPKM---QLVCCRAIVKVFL-ALAAKGPVLRNCISTVVHQGLIRICSKPVVLPKGPESESEDHRASGEVRTGKWKVPTYKDYVDLFRHLLSSDQMMDSILADEAFFSVNSSSESLNHLLYDEFVKSVLKIVEKLDLTLEIQTVGEQENGDEAPGVWMIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQAEFFEPWVYSFSYELILQSTRLPLISGFYKLLSITVRNAKKIKYFEGVSPKSLKHSPEDPEKYSCFALFVKFGKEVAV---KMKQYKDELLASCLTFLLSLPHNIIELDVRAYVP-------ALQMAFKLGLSYTPLAEVGLNALEEWSIYIDRHVMQPYYKDILPCLDGYLKTSALSDETKNNWEVSALSR--AAQKGFNKV--VLKHLKKTKNLSSNEAI-----------SLEEIRIRVVQMLGSLGGQINKNLLTVTSSDEMMKSYVAWDR--EKRLSFAVPFREMKPVIFLDVFLPRVTELALTASDRQTKVAACELLHSMVMFMLGK-ATQM--PEGGQGAPPMYQLYKRTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLEAILDGI-------------VDPVDSTL-RDFCGRCIREFLKWSI--KQITPQQQEKSPVNTKSLFKRLYSLALHPNAFKRLGASLAFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTIQQCCDAIDHLCRIIEKKHVSLNKAKKRRLPRGFPPSASLCLLDL-VKWLLAHCGRPQTECRHKSIELFYKFVPLLPGNRSPNLWLKDVLKEEGVSFLINTFEGGGCGQ--PSGILAQPTLLYLRGPFSLQATLCWLDLLLAALECYNTFIGERTVGALQVLGTEAQSSLLKAVAFFL 1298 HSP 3 Score: 187.578 bits (475), Expect = 2.214e-45 Identity = 277/1298 (21.34%), Postives = 544/1298 (41.91%), Query Frame = 2
Query: 4889 IDLLLEMMLIDSNICENNF------IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENI-KTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLL-ALFE----DELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL--------IGELSKICSLILYCKSDDSTNKLIY--QMIYNVRSW---AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLM-----------IINIPYDIVNDHPCMDTFICL-HHQMKNVGIIS--EVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNG---YLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFF--QLFVDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQ-----ELRSYSMSHDQKFKVPTSINIPKQAKN------------FDWIQLASTLQF-----PSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQEN----QTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFV 8518
+ LL +++ IDS++ N +F + +LL+ T L + K + + + F T G S + + + + +F S++ Y++ + L++ ++ ++ + CRE H E+ + + + + R ++ LL +++E D+ +L ++ F+++ ++ C + L FF + + ++ +K + F NE I KI+ +Y+ L +D V +E K+ I E +++ ++ D T + Q++ R + A+NC SV+ ++ KFY L KP +F ++I NFP E+ + ++ K+ + KE + +++ P + S +L+DS+L+ ++ + + S V S S GR ++ + D +N H CM L H +++G E + D+PSWMK H ++I+ F+ KL+IN +F+PYA W+ L++ + I+ V ++ I+ W+ + V K + N L+N+L ++ + ++ R N+E+ +L+ WK+ + IPY+ IF+ + N G+++L V+ N Y G + F + + + K V+ A E+ G++L+ +++ + E + E+ + + + + F+ CL + K+ + R ++ + +L LE++ C + E L+ QL + + ++++ + + ++ + + + +N VV+ P +T E+ L + + D SE + + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMTS PD+ P+F+ H S F+ T + L P FV + R+ S ++ V I +Q + FDW+ +ST PS + +K ++ + + G D K L L ++N+ K + + + + F + + Y ++ + REK ++ + K +++ V LYR+Y G LP+I+I++ S I PLQ +AQ + +K LF L++G+LKE + F Q L Q F+ L T +S I+ + + ++L+P+ V
Sbjct: 1646 LALLAKILQIDSSVSFNTSHGSFPEVFTTYISLLADTKLDLHLKGQAVTLLPFF----TSLTGGSLEELRRVLEQLIVAHFPMQSREFPPGTPRFNNYVDCMKKFLDALEL-----SQSPMLLELMTEVLCREQQHVMEELFQSSFRRIARRGSCVTQVGLLESVYEMFRKDDPRLSFTRQS---FVDRSLLTLLWHCSLDALREFFSTIVVDAIDVLK-SRFTKLNESTFDTQITKKMGYYKILDVMYSRL----PKDDVHAKESKINQVFHGSCITEGNELTKTLIKLCYDAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFS-EKPEKNLLIFENLIDLKRRYNFPVEVEVPMERKKKYIEIRKEA------REAANGDSDGPSYMSSLSYLADSTLSEEMSQFD--FSTGVQSYSYSSQDPRPATGRFRRREQRDPTVHDDVLELEMDELNRHECMAPLTALVKHMHRSLGPPQGEEDSVPRDLPSWMKFLHGKLGNPIVPLNIRLFLAKLVINTEEVFRPYAKHWLSPLLQLAASENNGGEGIHYMVVEIVATILSWTGL-ATPTGVPKDEVLANRLLNFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSGKDPNSKDNSVGIQLLGIVMANDLPPYDPQCGIQSSEYFQALVNNMSFVR--YKEVYAAAAEVLGLILRYVMERKNILEESLCEL---VAKQLKQHQNTMEDKFIVCLNKVTKSFPPLADRFMNAVFFLLPKFHGVLKTLCLEVVLCRVEGMTE---LYFQLKSKDFVQVMRHRDDERQKVCLDIIYKMMPKLKPVELRELLNP-VVEFVSH--PSTTCREQMYNILMWIHDNYRDPESETDNDSQEIFKLAKDVLIQGLIDENPGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTSMSPDYPNPMFE-HPLSECEFQEYTIDSDWRFRSTVLTPMFVETQASQGTLQTRTQEGSLSARWPVAGQIRATQQQHDFTLTQTADGRSSFDWLTGSSTDPLVDHTSPSSDSLLFAHKRSERLQRAPLKSVGPDFG------KKRLGLPGD--EVDNKVKGAAGRTDLLRLRRRFMRDQEKLSLMYARKGVAEQKREKEIKSEL---------KMKQDAQVVLYRSYRHGDLPDIQIKHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKTLSEKNNITQKLLQDFNRFLNTTFSFFPPFVSCIQDISCQHAALLSLDPAAV 2876
BLAST of DNA-dependent protein kinase catalytic subunit vs. TrEMBL
Match: H0VPX0 (Protein kinase, DNA-activated, catalytic subunit OS=Cavia porcellus OX=10141 GN=PRKDC PE=3 SV=2) HSP 1 Score: 552.747 bits (1423), Expect = 1.339e-153 Identity = 600/2497 (24.03%), Postives = 1070/2497 (42.85%), Query Frame = 2
Query: 5255 FCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKKL-----------IGELSKICSLILYCKSDDSTNKLIYQMIYNVRSW----AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLE---NILSRNVNSNLMDS-----------DSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGII---SEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSS---INPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNG---YLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQ---SALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNM---PQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEW--SSSQIPGVDMSLSI---------------KSQK-----------SFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIP-------YLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKADCFGXXXXXXXX--XXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKS-------------VVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQK---CDMPIDYISKLK---GNQGDLEKESLEFWENLLFYRTVYLKKGMMKF-PFLAEAITT--------------EISDLQMQFIDACIIHNRMSPAFXXX-------XXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLS-------LGDCYWTLGNVLS-----LHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESD------GNKKELSAALVVVSDFYDAQIRQFEN--DGPSR---------------PDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVTSKSN--------FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEF----YTQYFP------NTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQK------------RINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAET-----SQTKKLVSMATNSGFLARTWQGFEP 12088
CRE H E+ + T + + R + LL N+ F+++ ++ C + L FF + ++ +K + F NE I KI+ +Y+ L ++D V +E K+ EL+K +LI C + N + R A+NC SV+ ++ KFY L KP +F ++I + FP E+ + ++ K+ + KE + +Y S +L+DSSL+ ++ + + + S + NS S DS +Q D ++ + D +N H CM T L M+ I+ E + D+P WMK HD I+I+ F+ KLIIN IF+PYA W+ L++ + + S I+ V ++ ++ W+ V V K + N L+++L ++ + ++ R N+EL +L+ WK+ + IPY+ IF+ + + N G+++L V+ N Y G + F + + + K V+ A E+ G++L+ I K+ ++ E V E+ + + + F+ CL K + R ++ + +L LE++ C + E +L+ QL + + ++++ + + ++ + + + +N +V+ P + + + + D S+K D F+ L+ G ID + + IRNF S LP+ L+R + + P+ FL++ATN +LEMTS PD+ P+F+ H S F T + L P F+ P L+S + + P + + + +D+ P+Q + + S W SS P VD ++S +S+K F S+ E ++K +N+ E + + + K L Y ++ V++++ K ++ K +++ + LYR+Y G LP+I+I+ S I PLQ +AQ + +K LF L++G+LKE + F + Q L Q F++ L + +S +I+ + ++L+P V S LA++ + ++ + PP+K+++ G + +P L KLY+ + + + G+ SS + +AL A+ +Y+ + E + E E E + ++ +D LC+W L C S +++K ++ SKL+ L+ + E ++ +DE + R ++ EL E+SL YI+++D ++A+ + E + +YS L + LQSL L EI +FL + K P LK D + + W++++ R +L K K P ++++ E + I +C +M A S K + ++ W +K+ + + R + C S E ++ + ++ LL + NT ++ + LS LG + + + LS L P+ +++ +EL + + T + + GL ++F ++ + ++ G + A + + DF D Q+R+ E G S+ P L+ VE L ++KL A+ +FPRLLQII Q+ + + +T SSIP W +I W+ M+ LD + V+ + IA++YP A YPF++ + K F+ +I L ++ F AL Q+ P+ + W+ + D N + ++NI N Y+ M+ +GN G F+ F + F + +F + G+ + + F+ I ++ L K NLK+FSPW++++ +D LE+PGQY+ +P PE H +I + +++M S + PK+I+I G +E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ L KTY V+P++ LGL+EWI+NT TL EF M EE+ Y S++ Y ++ + Y + ++ T F + ++ + DLL+++F+ +S E+F LR +F +A+ +H+LLGIGDRHL NF+++ TG +IGIDFG+AFG AT FL IPEL+PFRLT + + P G+ + + L + + + M VF+ DW + + ++ QK +I S RKL +P ++ +EL + + +S+ FK N ++ + E+ +Q + L+ AT+ L RTW+G+EP
Sbjct: 1665 LCREQHHVMEELFQTTFKRIARRSSCVTQSGLLESVYRMFTRNDLLPNVTRQAFVDRCLLTLLWHCSLDALREFFSKVVVNAIDTLK-SRFTKLNESTFDTQITKKMGYYKILEVMYSRL----SKDDVHSKESKINQVFHGSSVTEGNELTK--TLIKLCHDAFTENMAGENQLLERRRLYHCAAYNCAISVICCVFNELKFYQGFLFS-EKPEKNLFIFENLIDLNRCYTFPIEVEVPMERRKKYIEIRKEARGAANEDSDGPRY-----MSSLSYLADSSLSEEMSQFDFSTGVQSYSYNSQDPRSATGHFRRRERQDSEIQDD-----VLELEMDELNQHECMATMTALIKHMQRNLILPKGGESSVPKDLPPWMKFLHDKLGNLSVPINIRLFLAKLIINTEEIFRPYAKHWLSPLLQLAVSENSGGEGIHYMVVEIVATVLSWTGV-ATPTGVPKDEVLANRLLHFLMKHVFHPKRAVFRHNLELIKTLVECWKDCLSIPYRLIFEKFSSRDPNSKDNSVGIQLLGIVMANNLPPYDLKCGIESTKYFQALVNNMSFVK--YKEVYAAAAEVLGLILQYITKEKNALEESVCEL---VMKQLRQHQNTMQDKFIVCLNKAVKGFPPLADRFLNAVFFLLPKFHGVMKTLCLEVILC---RAEEIPDLYLQLKSKDFVQVMRHRDDERQKVCLDIIYKMMAKLKPVELQELLNP-LVEFISHPSPMCREQMYNILMWIYDNYRDPESQK-DGDSQEIFELTKDVLIQGLIDENPGLQLIIRNFWSHETRLPSNILDRLLALNSLYSPKIEG-----------HFLSLATNFLLEMTSMSPDYPNPMFE-HPLSECEFREYTIDPDWRFRSTVLTPMFIETQASPSTLQSRTQEDSLPAQGPKAGQVRATQQQYDFT--------PTQTADGRS-----SFNWLTGSSIDPLVDYTVSSSSSESLSSSLLFAHKRSEKFQREPWKSVGPDFGQKRLSLPGDEVDNKVKGGTDNRAEILRLRRQFLKDQEK-LSLIYAKKGIVEQKRAKEIKSEL-KMKRDAQIVLYRSYRHGDLPDIQIKYSSLITPLQAVAQRDSLLAKQLFSSLFSGILKEMDRFKSVSESKSITQKLLQDFNHFLNNTFLFFPPFVSCIQEISCQHADLLSLHPPAVRTCS-------LASLQQPGGIHLLEEALLHLAPAEPPSKRIR------GRTHLPPDTLRWMELAKLYRSIGEYDVLRGI-----FSSEIGTKQATWDALLAEARSDYSEAAKRYNEALNKQEWADGEPTEAEKDFWELAS---LDCYNHLCEWKSLE---YCSTASVDSENPPDLSKMWSDPFYQETFLPYMIRSKLKLLL--RGEGEQSLLTFVDEAM-RGELQQALMELQYSQELSLLYILQDDIDRAKYYAEQGIQIFMQ---NYSSIDVLLHRSRLTKLQSLQALTEIQEFLSFISKQGNLSSPAALKRLLKTWTNRYPDANVDPMSIWDDVITNRCFFLSKIEEKLAPLFEDSMSADDEEEDHSGGQGGAEPEEGVASLIRSCRFSMKMQMAASARQQDNFSLAMKLLKELHKESKTRADWQVKWVQSYCRLSHCRSRAQSPTER---ILTVLKTISLLDE--NTTSDHLNQNTLSSCDQNILLGTTFRIMADTLSTDPACLAAMEGPKARLV---VELSGSSTEST-ERVTAGLYQRAFLHLSRAVQTAEDAQPPCQGPGPAASMIDAYMTLVDFCDQQLRKAEEYASGESQKKKTITTDSVELQVYPALV---VEKMLKALKLNSTDARLRFPRLLQIIEQYPEETL--SLMTKEISSIPCWQFIGWISHMVALLDKEEAAAVQPTVEEIAENYPQAAVYPFIISSESYSFKDTPAGRKNKEFVARIKSKLDQGGVIQDFINALDQLSNPDLLFKDWVADVRDELGRNPVN---KRNIENLYRKMH-AALGNPQAPGLGPFRRRFIEAFGKEFDKHFGKAGSELLKMKLRDFNAI---VDTLLFKMKKDAKPPGNLKEFSPWMSEFKVE--------FLRDELEVPGQYHG-RGKPLPEYHARISGFDERVKVMTSIRRPKRIVIRGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNVILSRDAACSQRSMGL---KTYRVVPMTSRLGLIEWIENTFTLKEFLLNNMSQEEKEAYTSNSTKAPMMDYKEWLAKMPGKHDEGRYVPMYNNANRTETVMAFRKRESKVPA-DLLKRAFVKMSTGPEAFLALRSHFSTSHALLCVSHWLLGIGDRHLSNFMVSMETGGVIGIDFGHAFGSATQFLQIPELMPFRLTRQFINLMLPMKETGLMYSIMVHALRAFRSDADLLTNTMDVFVREPSFDWKNFEQKMLKKGGSWIQKVNVTEKNWYPLQKICYSKRKLAGANPAVITCDELFLGHEQSSAFKSYIAVTRGSRDHNVRAREPESGLSVETQVRCLLDQATDPNILGRTWEGWEP 4041 HSP 2 Score: 227.254 bits (578), Expect = 6.788e-55 Identity = 287/1272 (22.56%), Postives = 558/1272 (43.87%), Query Frame = 2
Query: 434 VKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKIL--HMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQ-EQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSIN----------TDSNETDLIKSYAAL-STRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEKIN--------TDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIK---KWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKIC----NYNDELLITCLTLLVNSP-IFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPH--MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT----WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRI---VPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQ-LSFCYDETNPNSFFKALLTAKPLEYITKKFES--------------TELFKI--PPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYF-TKGVSNLFTAVNNFL 4027
V +K +AK + +L IK LQ + + + F+ +G + + +L + K TVL + EL+G + ++P+ +YS + L L+ ++ ++ K +++GC +GL F K++ E + I+ LK + +D R+A + L T H + + + +F + K +H N+ LK A + L+ +L+ Q+ + + + +Y QF ++ + S +K L I+G G C V+ K+ + +Y + + + +L + D + +P + + IA +L+ L + + +L++ ++ + F ++SP++ ++F A+ + V + I +V+Q +I CS PV I+Q + + S+ + +I T + DL K + DFL L N + L++D F+K KI+++LDL + + E N +DP + PKDF F+NL + F + E ++K W L+ +S LPL+SGFYK++ ++ +F E + +D Y L +++ Y DELL +CLT +++ P + I ++ + P LQMA +LG Y PL + ++ L+ W + + K ILP L S +S + K + E++ + ++K S +++ + + + S N LE+++ R++++LG +G + ++ L+ S + W++ E + + +PF+++KP I L+ + ++ LAL+++ Q K A E+LHSL++ +LGK AT I E+ + +P + + F + ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD GQ + FLK S + VN K +R+Y L + + +KRLGA FN+I+ + + L+E +F + +E L+ D K LGT+ Q A ++ + L K R+ PPS + ++ + WLL + + R I+L + + +P+ + ++ + + ++ FE LF + P S A+ W++ L A+++ + + ++A TK S+L+ +V FL
Sbjct: 14 VYTKDRAAKCRIPALDLLIKLLQTLRSCRVIDEFK--VGELFNKFYGELALKTKVPDTVLEKVYELLGVLGEVHPSEMINYSENLFRAFLGELKTQMTSAVREPKLPVVAGCLKGLASLLCNFTKSMEE--DPQMSREIFGFALKAICPQIDLK-RYAVPLAGLRLFTLHASQFSTCLLDNYVSLFEILSKWCSHTNIELKKGAYSALESFLK------QVSYMVAKDAEAHKSKLQYFMEQFYGIIRNVDS-----NNKELSIAIRGYGLFAGPCKVINAKD-VDFMYVELIQRCKQVFLTQTDTFDDHVYQMPSF-LQSIASVLLYLDTVPEVYTP-----VLEH-----LMVVQMDSFPQYSPKMQSMCCKAIVKVFLALAEK----GPVLWNCISTVVHQGLIRICSKPV-----ILQKGAESESENQRAIGEVRAGKWKVPTYKDYVDLFKQLLSCDQMMDFLLADETFLFVNSSLQSLNRLLYDEFIKSVLKIVEKLDLTLQKQAGEQEDENEAVWVIPTSDPAANLHPAKPKDFSAFINLVE---FCREILPEKQVKFFEPWVYTFAYELILQSTRLPLISGFYKLLSISVRNAKKMKYF----EGVSPKSLKHSPEDPEKYSCFALFAKFGKEVSVKMKQYKDELLASCLTFVLSLPHVIIELDMKAYVP-------ALQMAFKLGLSYTPLAEVGMNALQEWSLHIRKSIIQPYYKDILPCLDGYLKTSTLSGET------KNIWEVSALSQAAQKGF----SNAVLKHLKKTKNLPS-----NEAVSLEEIRIRVVQMLGSLGGHINKNLVTAASSDEKMKKCVAWDR--EKRLSFAVPFREMKPVIYLDVFLPRVTELALSTSDRQTKVAACELLHSLVMFMLGK-ATQI--PESGQGLPPLYQLYKHTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGI-------------VDPIDSTL-RDFCGQCIREFLKWSIKQTTPQQQEKSPVN--TKSLFKRLYSLALHPNAFKRLGASLAFNNIYREFREEESLVEQFVFEALVIYMESLALAHADEKSLGTVQQCCDAIDHLRRIIEKKHTSLNKAKKRRLPRGFPPSASLCLLDL-VMWLLAHCGRPQTECRHKSIELFYKFVPLLPGNKSPSLWLNDVIKKEDISFLINTFEGGGSSCDRPSGILAQPTLFHLRGPFSLRAALRWLDLLLAALECYNTFIEEKTVEAQEVLGTKAPSSLWKSVAFFL 1197
BLAST of DNA-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A2C9K058 (Uncharacterized protein OS=Biomphalaria glabrata OX=6526 GN=106074827 PE=3 SV=1) HSP 1 Score: 550.821 bits (1418), Expect = 5.233e-153 Identity = 623/2595 (24.01%), Postives = 1125/2595 (43.35%), Query Frame = 2
Query: 4952 DFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLL----ALFEDELKLI-----KAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQL---LENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLI-GEL-------SKICSLILYCKSDDSTNK-LIYQMIYNVRSWAFNCFSSVVIATQSDEKFYTNLLLRYN----KPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLM-----------------IINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVY---LSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKM---SSINPFVESVLRLIIDW--SSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVS-KGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELL-GCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFV-------DLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVN--MPQELRSYSMSHDQKFKV--------PTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQ---------------IPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINK--TIETNYTKELDND--YFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIP-PAKKLKLSETNTGSSLIPY--LMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKADCFGXXXXXXXXXXXXXXEASVDENNEFEYEL--LSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKS-------------------VVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYSLSSEADTLM-------LQSLHFLNEICQFLQAVQKCDMPIDYISKLKGN--QGDLEKESLE---FWENLLFYRTVYL-----KKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDI-----NYSLEYLLSLGDCYWTLG-NVLSLHWQSEPENKIINSILELIDHTG-DYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSA-----ALVVVSDFYDA------QIRQF--ENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVA--DVTSKSNFICKIGKILSNLK--------------LVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKII----------------GNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIY--KKVSSEFYTQY---FPNTAAYTKSWEK--------SDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMS-RMSKQSIET------FTQKRINISHRKLKREDPLLLLYEELQIKYGKS--------NWFKCMKN------FQSEDAET-SQTKKLVSMATNSGFLARTWQGFEP 12088
D + +L + KN+ + + FF A + K E + F NF S + + S + Y+ +I + +++ L++ I+I ++CRE+ H H + ++ + +RL ++++ + ++F ++ + A EN+ I+ L FF S I ++ L+ N E+ E +L I +++ +Y L + + +KL G++ KI +S+D + L+ + +A+N +++ Q+D KFY L + N + L +I+ + F E+ + KF ++ + D+ +H +++L+DSSL D+ + + +S N S L D + R I + D +N H M + I + M I EV L +++PSWM H+ A ++++ FI KL++NC IF+PYA FW+ + L+ K + F ++ +I W S++P +A + ++ +++N Y I R N+ L SLL +W ++VDIPY I++ L+N K +++ G+++L VL + + ++ L ++ + K V A E+ G+ +K + K+ ++E LT ++ + + F+TCL I ++ + + S L+ +L L + + LELL G N +L+L + E + ++S V +++ H +T + + ++ + S R + ++F+ D+ E + ++ + ALL G D D NF SS+ LP TLER+ +LE ++ + +LA ATN++LE TS PD+ + IF+ H S TF++ + Q + P F + + Q + + S D + PT +++ A+ F+W+ +S + Y D S +SSQ IPG + K ++ ++ + N A+N+ E Q+ + + K+ ++ + V+ L + K +K + + V LYR Y G LP+I+I+ IAPLQ LA + ++ LF L+ + E + + Q+++ +IL+ + S L I S + ++ S V +S S + L ++LE+ LI K DS E+ +KK + + + L + L +LYK N + + G+ S ++ ++A++A+ G++ + +Y+ ++++ + + E E+ +S+ ++ L L +W +L ET+S + + + V+ SKL+ L+ + ++ ++ +D + Q + E E++L + ++ Y++++ +C +++ L C+ + TLM LQ L L E+ +FL +V + S L N +G L + L+ W+++ R Y+ + M + ++ L++ D C N + L+ ++ D+ L W Y+ H SA G + +I + +++LL K I + LE+ + G+ Y L VL + + E + L G + +KD + C L++K + + + N+K+ A A + ++ F D ++ +F E D P+ I V L +MK A+ +FPRLLQ+ ++ D+ D A + +PSWM++ W QM +D S +V ++ RIA+DYP AL YP + D KS KI K N + LV++F +AL Q GQP+ + W DM D +S+ + K Q++Y +++ + G+F++ FS F+A+ + F +DG + ++ F + N + K + LK +SPWLA++N P+ KD LEIPGQY +P PE H+KI + + +M S + PK+I+I G++EQ Y +LVKSGEDLR D RIE +F +MN +M+ D+ + L KTY V+ ++ +GL+EW+ +T L F + +EE+ ++ S+ Y Q+ N A Y W+K + T ++F + + +DL R++ ++S E+F+ L+ I+ +A+ YLLGIGDRHL NF+++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT ++ P V G T+ +VL L + ++ M VF+ LDW + R +S + + +K+I I+ KLK + P ++ +EL+ K K K+ FQ+ D Q L+ AT+ L RTW G+EP
Sbjct: 1681 DMYQCILKDPKTNMAIKNEAL-VLLPFFVTAKSQQDKYLK--ETLDRFIVDNFPLTSTEFEPGTSKYKDYITAIDRILVAMEM-----TGSLMLLNIVISVYCRETEHIHSEAIQLGINRFVQRLPLDQQLLAMDVPFSVFVNDNSYLPHVRRAAVENVC-------LPILRVVSTSALVQFFSSHIQEIIRYLDQTLNKNVESALENQLSTKIGCFQLLEIMYARLSKEEVNSQTSVINQKLCEGKVDTGKEMTQKITKCAHEARSEDVRGETLLPDLRRQYHCFAYNLLIAIISCVQTDLKFYKGFLFQDNISKGQFLLENIVDTNKKYEFTVEVKSPVQRHKKFVSIRNIAHEMRAESNGQDESASPSLHLASQYLADSSLNDDLNQFDFNMSSNWQSELYDPITTSDRSTRGGHSASQENKVTTEEPSSQDYIELEMDALNRHESMASLIAVIKHMSIAKITPEVSPGNLPTEMPSWMSYLHEKMSAAFSAVNVRLFICKLVMNCSQIFQPYAKFWLKPFGQLLLEKTVCGEGLTYFAVDIIITMITWHKSAIPADTTD-ERALASRIVRLVSDNIYHPVRQIYRNNLTLLKSLLEVWHDRVDIPYDTIYNLLKNTDPKSMKSTTGIQILGVVLAGKFPPYGPVAPVDRDRYLSSLCVLMSNCYKAVHAAAAEVIGLAMKWLEKNC-KETEGPFHDSAIAQLT--SLSNNNLGIFITCLHCIHLSYPPLCFKFQSKLLYVLPKLHCHFKVQCLELLLGQVYEMENVYLQLKG------LSEYLIHRSEDVQLVALKIVHAVMTRLK--------GSELLSFLKVGTTFSGHPNPACRKIMLEIFMWSYDNYRDMEDEDSAPI-MSVTKEALLRGLCDEDFACRLVCLNFWSSNTRLPEGTLERTISMLEAMYSPNT----------EPHYLAYATNLLLEATSKSPDYQREIFE-HALSECTFQDYSVHSSWRQRHAVMTPLFASTFVTQSMETGQDSLDGGLRATQDMPQFTPT-MDMTGTARAFNWLTQSSL----------DTYADPGSSVGASSQLLFNVGSSSQHRNLLIPGQKGEATAKKTFAWKKIT-----LNNIKPAANKDETDGSVQSHEDIWRLRRRFVKDQQAQSLFYIRRNVKINTLREEILKEQKARRENQVTLYRKYRIGDLPDIQIKYQYIIAPLQALAHRDSTVARLLFSSLFQAIFCEMDKLKTETEIKQLVQHINDSISHILRESLYYFPPFLGSILTILYELRSSLKVSASDVGTSSITSNQQSLGIMVLEENLI------KSDSTEVAHRSKKSRQTRSLPSPELAEWIQLSRLYKSANEFDIVQGI-----FSDQLGTKDQTRKAIEAEARGDFKTANLIYSQIIAQQDWKDGDPLEAEVDFWDISR---MECLDHLSQWKDL---------ETISVKGVDSSDQPNLDRVWDDGFYQEQYLPYVIRSKLK-LLLSGDANQQSLLTFVDNCMTDLQKK-QHLENRYCSELALMSLWQQSYDRSRHYCNMAFRGFLQDWCNTT------TLMVSSCRKNLQQLQSLVELKEFLDSVGPDHKVLPSASTLLINAWKGRLPHKLLDPVPVWDDITHNRIAYINLILDQLSDMNINHTITELHKAMASLRLAMADCCQTQNNYTLTLRLLRDTQTVCKNSDQELFLRWSHLYTAAHQSSAKSKGHPWT----DDIFSNIATTLELLKKLEEYAILLERSDLRLEHQILTGEGYGLLAQGVLKFDYLPDLEQGTLKKCYSLATPEGMEVSKDKMFCQLVDKGYNYLKAAVCQDMDDQLNEKKRQAITMEEANLRLAKFCDKYLILGDEMERFPKECDRTLFPETI---VLCLLNAMKGGSEEARERFPRLLQL-SELFPDVRDVFIKKA--AEVPSWMFLMWTSQMTALMDKDESVVVSPLLERIAEDYPQALIYPLHMSSEGFDFIPKSE--SKIEKYQLNRRKETVDRLNSKIHNVLVYKFISALEQFGQPDIIFKDW---CTDMKRLLGKDKSSKDEVRRKCQEIYDQLLNVKGDTTASSTQINYSATAASVGMGEFRKGFSDNFKAEFEKVFGKDGCKLISMNAKDFQGAEACLRNLIDGKKGLFNPPTKLKAYSPWLAEFN-------PNKFGKD-LEIPGQYTG-QQKPTPEYHVKIAGFDERVLVMSSLRKPKRILIRGNDEQDYPYLVKSGEDLRLDQRIEMLFFMMNKVMNSDWACKQRKLQL---KTYQVVSMTPRVGLIEWMRDTCPLKNFLYNALTEEERKFLDSERGPSKVYNQWICKLVNKAQYGH-WQKIFDEVYIKYNYTETIKQFRLLEGTVP-WDLSRRALHSMSSSPEAFHVLKSAMIKSHAVICICQYLLGIGDRHLSNFMVDLKTGQLIGIDFGHAFGSATEFLPVPELMPFRLTRQLINLSLPLKVKGQMESTMRHVLRALRADSDLLLRTMDVFVKEPHLDWLNFAERQKDESADAECENTWYPEKKIIIARCKLKGDHPSYIMMQELESVKAKREKVYTYICGVLKGQKDENVRFSFQAHDLTVEEQVAALIDQATDPNILGRTWTGWEP 4154 HSP 2 Score: 291.197 bits (744), Expect = 2.575e-74 Identity = 330/1351 (24.43%), Postives = 598/1351 (44.26%), Query Frame = 2
Query: 365 LVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMKELSIKSLQDILTLTGNNNF--EMNIGVCLSDLFSQLQ---NKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEI----NNSKTSIISGCCEGLRRFYKALPEKL--SAKSPPTIYLLLLKILHMDSGY-RFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREA-FEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYL--LEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSND----DKDECSVLIFDSFMKCAYKIIDQLDL-LYKSEDVNN-----------EKINTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINL----ECTKVADNRGLC----------KDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLL--LFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRY--LIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPT---WSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKN-----RIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDE-TNPNSFFKALLTAKPLEYITKKFES-----TELFKIPPSPVN-----------AIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSN---LFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILI 4183
L KF K++P+ IK +++ S+ AK+K+ +I + IL T + E+ I + F++L +K TV + + L+G + L+P+ YS G+ ++ L+ E+ + SI++GC EGL F + +K I+ L +++ D Y R+ A+K+ L L H ++ + + + ++ + K +H N + ++ + + + E + + H+ A F++ FN +K S + K + IKG G L C + L + +++ + ++L LE+ ++++ S LP Y LISL I+ Q + + P V+ +L + +E P++ + + + ++ LK TV I+ +VYQ++I +CS PV + S D +L+ EY I S + D I +A L ++ L + D ++DE + I++ M KI+++LDL SED + E ++ DP+ G A PKD +I +N+ + + ++ K W + S + PLVSGFYK++C+++ ++ +F+ + + ++++D+ + K + IK +L ++ Y DELL CL+L + P I I++Q + + +Q +G YLPL LD L+ W P LI P Y +L L + + +D D E A + ++ S+++I+ + + D NS +L L+ R+++ LG +G + + L + + S I W+ + +++PF D+KP I L+ + + LA S+ Q K A E+LHSL++ LG+ A + E K P + +F ++LA D+ V K LF L++Q+ +WF+ +++P +D FD +I S+ +++ RD + L FLK S K I+ +K +K L+RIY + + KRLGA FN+I+ +L+ + L++ F ++ + V+ L+ D K LGT Q A +++ R +K+K+ + K+ R P SW++ +EFA+RWL + + R C+ L L PN+FF L ++ Y ++FE +E I P A W + L A++ +CWL L+ F S +F ++ FL +L+ N I+ +FS D F ++ N M+ ++I
Sbjct: 88 LQKFGS-KVVPYAVDIKETCVSLY-SRDRHAKVKKAAIPVIIKILEQTASTTTAEELVIDDLIKKFFNELAKPVSKLQPTVRAGIYHLLGVLAELHPDMIADYSERLAGVYVSALKVELMSKNKEPEMSIVAGCLEGLSCFMLNFTQSAEEGSKHAYEIFKYLRMVINADIDYSRYEAIKAALKLLVRHAGQMRQFMIDEYKWMYEQLQKWSHHRNKEVVHLGVAAMEAFTKEVSEAL----VDRAKQGHKEGAIFKFFLLNFNKIMKNPNS-----SSKEVSMAIKGYGLLAAPCRIFLSEVDTQFMFNEMVSQCEHQFLGKLEEIEDKLMS-LPSY--------LISLANIIS------QIDSVSLPNSL-VLEKLMVLLMEHIPKVNQSQQFYCVKSILILLLCLKRKPTVFQQILTSVVYQSLIRTCSHPVVAETSQT-DENLD----EYGIKKISYK-DYISLWATLLGSCQMKVTTQDLSAEDFTLAERDELTHSIYNEIMTAILKILNKLDLEATTSEDSDKADAQSEVSGDKETLSADPIFGLVAKRPKDQLILINIVDFSRDLIVHHQRHRFKNWVYTFTYSAIVLSTKHPLVSGFYKLLCTVMTVVCKLKYFKDVVSKTSQSSRLSDSMDVDEPETQENQFEKVQTYQLIKKFTKEVLVRMKQYRDELLAACLSLTLALPEEI-IQDQMAN-----IVPAIQTTFIMGLSYLPLANIGLDALQYWSDNLP-----ASLIEPYYAEILPYLDAYLRTD---DKGSDMTVEPAVLVPSKKAEVKSKVSVRLIKGKPA--------ADQNSETQLTSLKLRILQYLGSLGGQHISHALLAKSDEEISSAAIAWDTQKH--LKFDVPFIDMKPSIYLDPFLPQVVKLAKQSSDRQTKVAACELLHSLVLYALGRGAQ--MPGETQKKYPMEQLYRKLFPSLLQLACDVELVCKELFEPLMLQLIHWFTNNKMAESPETMALLDCIFDGLIQ------SNDMAL--------RDFCAKCLREFLKWSL--KQISKKSAEKNPINVKSVLKRIYSFSAHPNASKRLGAALAFNNIYMVLREEDALVDRFTFEILVHFVDSLSLAHYDEKSLGTQEQCVKALEHL---ERIMKTKVDILKKDPGPKIRPEPSSWSSRKLEFAVRWLTRQCGNPQTECRHSCMKLVYNLCVLLPGIKTPNAFFAILHKSEGPIYFLRRFEGGGQGYSESHGILAHPTMIEYRKTFSLEVAREWFDLLLAALDCYCWLFGQELMIPSQIFKGKESERSCIFVSLEFFLK------------RLAFNDIAAASRLFSHRDNFTFTPREIEEYNRMKCTVII 1348
BLAST of DNA-dependent protein kinase catalytic subunit vs. TrEMBL
Match: G1L084 (Uncharacterized protein OS=Ailuropoda melanoleuca OX=9646 GN=PRKDC PE=3 SV=1) HSP 1 Score: 542.732 bits (1397), Expect = 2.366e-152 Identity = 566/2286 (24.76%), Postives = 1008/2286 (44.09%), Query Frame = 2
Query: 5747 AFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDS-------FLQHDGRCLMI----INIPYDIVNDHPCMDTFICLHHQMKNVGII--SEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLT----------------------ASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQ-ENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPY--LMKLYK----VXXXXXXXXXXXXXXQLSSSKNLVEK---FKEALKADCFGXXXXXXXXXXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELT------------KFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQK-----CDMPIDYISKLKGNQ-GDLEKESLEFWENLLFYRTVYLKK---------GMMKFPFLAEAITTEISDLQMQ------FIDACIIHNRM------------SPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKV-HLRSAI--CHGSFTSFNEAPEILIGLTNSVKL---LLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQ--SEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSE-------SDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDL-IRSY----VESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFP---------NTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFK------------CMKNFQSEDA--ETSQTKKLVSMATNSGFLARTWQGFEP 12088
A+NC SV+ ++ KFY L KP +F ++I FP E+ + ++ K+ + KE + +S+ P + S +L+DSSL+ ++ + + S V S S F + + + M+ + + D +N H CM T L M I+ E + ++PSWMK HD ++I+ F+ KL+IN +F+PYA +W+ L++ ++ + I+ V ++ I+ W+ + V K + N L+++L E+ + ++ R N+E+ +L+ WK+ + +PY+ IF+ + + N G+++L V+ N + + LV + K V+G A E+ G+ L+ + + E V E+ I + + + F+ CL KN + R ++ + +L LE++ C + E +L+ QL N + ++++ + + ++ + + + +N VV+ P + + + D S+ D + L+ G ID + + IRNF S LP+ L+R + NS+ S ++ FL++AT+ +LEMTS PD+ P+F+ H S F+ T S + ++T LP M +++R+ +D T +F+W+ +S ++ ++ S+ ++ + + + S F + E ++KA + +N+ E + + T+ K L Y R K + +QK + + K ++ V LYR+Y G LP+I+I+ S I PLQ +AQ + +K LF L++G++KE + + Q L Q F++ L T +S +I+ + ++L+P+ V S + + LLE+ L+ HL + PPAK+ + T +I + L KLY+ L + +Q++ S L E + EA K + + + +EA D +EL S +D +L +W L LN M E + + ++ SKL+ L+ + E ++ +DE V + ++ EL E+SL YI+++D ++A+ + E + + +YS L + LQS+ L EI +F+ + + P+ + K N+ D + + + W++++ R +L K G + +++ ++Q Q I CI +M S A LK ++S D + ++ W Y ++ H RS C + + +L G + S L +L F + +I LG Y + N LS +E E IL+L + + + +I GL ++F+ ++ + E G L+ A + + DF D Q+RQ E + +++Y V+ L ++KL A+ KFPRLLQII + + + +T SSIP W +I W+ M+ LD + V+ + IA++YP A+ YPF++ Y TS + F+ +I L ++ F +AL Q+ PE + W DE + + ++NI Y+ MY +G+ G F+ F + F + +F + G+ + + + F++I + + ++ NLK+ SPW++ + ++ LEIPGQY+ +P PE H +I + +++M S + PK+III G +E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ L KTY+VIP++ LGL+EWI+NT TL +F M EE+ Y +Y + +AY ++ + T F ++ + DLL+++F+ +S E+F LR +F +A+ +H++LGIGDRHL NF+++ TG +IGIDFG+AFG AT FLP+PEL+PFRLT + + P G+ S + + L + + M VF+ DW +M + I+ + +++++ + RKL +P ++ +EL + + K+ F+ ++ Q E E +Q K L+ AT+ L RTW G+EP
Sbjct: 89 AYNCAISVICCVFTELKFYQGFLFS-EKPEKNLLIFENLIDLKRCYTFPVEIEVPLERKKKYIEIRKEA------REASNGDSGGPHYLSSLSYLADSSLSEEMSQFD--FSTGVQSYSYSSQDPKSTPGHFRRREHKDPMVQDAVLELEMDELNQHECMATMTALIKHMHRNQILPKGEDSVPRNLPSWMKFLHDKLGNPSVSLNIRLFLAKLVINTEEVFRPYAKYWLSPLLQLVVSENNGGEGIHYMVVEIVVTILSWTGLATPVG-VPKDEVLANRLLHFLMEHVFHQKRAVFRHNLEIIKTLVECWKDCLSVPYRLIFEKFSSKDPNSKDNSVGIQLLGIVMANNLPPYDPKCGIESIKYFQALVGNMSFVKYKEVYGAAAEVLGLTLRYFTEKENVLEELVYEL---IIKQLKQHQNTMEDKFIVCLNKAVKNFPPLADRFMNTVFFLLPKFHGVMKTLCLEVVLC---RAEEITDLYLQLKSKNFIQVMKHRDDERQKVCLDIIYKMMAKLKPVELRELLNP-VVEFISHPSPVCREQMYNILMWVHDNYRDPESQADDESREIFKLAKDVLIQGLIDENAGLQLIIRNFWSHETRLPSNILDRLLAL--------NSLYSPKIEMH---FLSLATDFLLEMTSMSPDYSNPVFE-HPLSECEFQEYTIDYDWRFRSTVLTPMFIETQASQSALQARTHEGSLPAQGVMARQIRATQQQYDF-----TPTQTADGRSSFNWLTGSSIDPLVDYMVSSSSDSSSSSLLFAHKRSAKLQRAPSKSVGPDFGKKRLGLPEDEVDNKAKGKGIDNRAEILRLRRRFITDQEK-LSLIYAR-KGIAEQKREKEFKSELKMKHDAQVILYRSYRQGDLPDIQIKYSSLITPLQAVAQRDPIIAKQLFGSLFSGIIKEMDKYKTVSEKNNITQKLLQDFNHFLNTTFSFFPPFVSCIQEISCQHTDLLSLDPASVSAGCLASLQQPVGIRLLEEALL-HLVPQE------PPAKRFQ-GRTRLSPDVIRWMELAKLYRSIGEYDVLRGIFSSEIGTKQVTHSAILAEARSDYSEAAKQ--YNEALNKREWVDGEPAEAEKDF-----WELAS------LDCYNQLAEWKSLAYCCTVSVDNASPPDLNKMWSEPFYQETY--LPYLIRSKLKLLL--QGEAEQSLLTFIDEAVNQ-ELQKALIELHYSQELSLLYILQDDVDRAKYYIENCIEIFMQ---NYSSIDVLLHRSRLTKLQSVQTLIEIQEFISFISRQGNLSRQAPLKRLIKTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLTLPPGDHSMSMDGDGDSSDKMEVQTQGEEVCSLIKNCIFSMKMKMVESARKQHNFSLAMKLLKELHRESKTRD-DWQVHWVQSYCRLSHSRSRGQNCPEQILTALKTASLLAGESTSSYLSKNVLAFHDQNI--------LLGTTYRIIANALSREPTCLAEIEESKARRILDLSGSSSE-NPEKVIAGLYQRAFHHLSEAVRTAEEEAQPSLRGSGPVASLTGAYMTLVDFCDQQLRQEEESASVTESIELQTYPAVMVDKMLKALKLHSSEARLKFPRLLQIIELYPEETL--SLMTKEISSIPCWQFIGWISHMLALLDKEEAVAVQHTVEEIANNYPQAIVYPFIISSESYSFKDTSTGHKNKEFVARIKTKLDQGGVIQDFISALEQLSNPEMLFKDWTDEIKVELAKTPVN---KKNIEKMYERMY-AALGDPRAPGLGAFRRRFIQAFGKEFDKHFGKGGSKLPGMKLHDFTDISDSLFYKMCR---DSKPPGNLKECSPWMSDFKVE--------FLRNELEIPGQYDG-KGKPVPEYHARIAGFDERVKVMASIRKPKRIIIQGHDEKEYPFLVKGGEDLRQDQRIEQLFEVMNVILSQDTACSQRNMQL---KTYHVIPMTSRLGLIEWIENTFTLKDFLLSNMSREEKAAYTSDPRAPPCEYRDWLTKMSGKYDVSAYVSMFKAASRSETVTSFRRRESKVPA-DLLKRAFLKMSTGPEAFLALRSHFASSHALMCISHWILGIGDRHLNNFMVSMETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFINLMLPMKEAGVMSSVMVHALRAFRSHSDLLTNTMDVFIKEPSFDWKNFEQKMLKKGGSWIQEINVTEENWYPRQKVHYAKRKLAGANPAIITCDELFLGHEKALAFRDYVAVARGSKDHNIRAQQPESGLSEEAQVKCLIDQATDPNILGRTWIGWEP 2277
BLAST of DNA-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A287DCQ8 (Protein kinase, DNA-activated, catalytic subunit OS=Ictidomys tridecemlineatus OX=43179 GN=PRKDC PE=3 SV=1) HSP 1 Score: 546.969 bits (1408), Expect = 7.200e-152 Identity = 627/2644 (23.71%), Postives = 1136/2644 (42.97%), Query Frame = 2
Query: 4820 NWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNIC----ENNF--IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENI-KTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKK---------------LIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNS---NLMDSDSFLQHDGRCLM--------IINIPYDIVNDHPCMDTFICL-HHQMKNVGII--SEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDI---LFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNM---PQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEW--SSSQIPGVDMSLSI-----------------KSQKS--------FLNLSTSVMHIENEDKASNQQENQTEFQTINK-------TIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIP-------YLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKADCFGXXXXXXXX--XXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELT--------KFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQKCD-----MPIDYISKLKGNQ-GDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISD---------------------------LQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKV-HLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLL--SLGDC-----YWTLGNVLSLHWQSEP-------ENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESD------GNKKELSAALVVVSDFYDAQIRQFENDGP--------SRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYF---------PNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFK--------------CMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEP 12088
NW + D S++ + + + LL +++ IDS++ N+F +F + +LL+ + L + K + + + F T G S + ++++ + NF S + Y++ + L++ ++ ++ I CRE H E+ + T + + R ++ LL + N+ F+++ ++ C + L FF + ++ + + F NE I K++ IY+ L +D V +E K L +L K+C + L + +Y+ A+NC SV+ ++ KFY L KP +F ++I FP E+ + ++ K+ + KE + +++ P + S +L+DSSL+ ++ + + S V S + D S H R ++ + D +N H CM + L H +N+ + E + D+P WMK HD ++I+ F+ KLIIN +F+PYA W+ L++ ++ + I+ V ++ ++ W+ + V K + N L+++L ++ + ++ R N+E+ +L+ WK+ + IPY+ IF+ + + N G+++L V+ N + + LV + K V+ A E+ G++L+ + + E V E+ + + + + F+ CL K + R ++ + +L LE++ C + E +L+ QL + + ++++ + + H+ + + + +N VV+ P + + + D S+ D LF + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMTS PD+ P+F+ H S TF+ T + L P F+ P L++ + + P + + + +D+ P+Q + + S W SS P D ++S KSQ++ F S+ E ++K + +++ E + + + Y K+ ++ REK ++ + K +++ V LYR+Y G LP+I+IQ+ S I PLQ +AQ + +K LF L++G+LKE + F QNL Q F+ L T + +S +I+ + ++L+P+ V A+ L G ++ + + PA+ L ++ + G + +P L KLY+ + + + + SS + + AL A+ +Y+ + E E E E + ++ +D L +W L L+ M E L + F ++ SKL+ L+ + ++ +DE + + ++ EL E+SL YI+++D+++A+ + E + +YS L + LQS+ L EI +F+ + K D +P+ + K N+ D + + + W++++ R +L K K +++ + + + ++M+ I++ N S A LK ++S D N ++ W Y ++ H RS PE ++ + +V LL D N + YL SL C T +++ SEP E+K ILEL + + + ++ GL ++F +K + E+ G + + + + +F D Q+ + E + P ++ VE L ++KL A+ KFPRLLQII Q+ + N +T SSIP W +I W+ M+ LD + V+ + IA YP A+ YPF++ Y TS + F+ +I +L ++ F AL Q+ P+ + W+ E D + + ++ I Y+ MY +G+ G F+ F + F + ++F + G+ + + + F++I N + L + NLK+ SPW++++ ++ LEIPGQY+ +P PE H +I + +++M S + PK+III G +E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ L +TY V+P++ LGL+EWI+NT TL +F M EE+ Y S +Y + AY +++++ T F + ++ + LL+++FM +S E+F LR +F +A+ +H+LLGIGDRHL NFLI TG +IGIDFG+AFG AT FLP+PEL+PFRLT + L P G+ + + L E +++ M VF+ DW +M + I+ + Q++I + RKL +P ++ +EL + + K F + S +E +Q K L+ AT+ L RTW+G+EP
Sbjct: 1541 NWRKCD--SWWAKDSAPESKMAVLALLTKVLQIDSSVSFNTNHNSFPEVFTTYTSLLADSELGLHLKGQAVILLPFF----TSLTGDSLEDLKHVLEMLIVSNFPMNSNEFPPGTLRYNNYVDCMKKFLDALEL-----SQSPILLQLMTDILCREQQHVMEELFQATFKRIARRNSCATQLGLLESVYRMFRRDDLLSNVTRQAFVDRSLLTLLWHCSLDALKEFFSKIVVDAIDVLN-SRFTKLNEATFDTQITKKMCYYKMLDVIYSRLP----KDVVHSKESKINQVFHGSCITEGNELTKKLIKLCHGAFTENMAGESQLLERRRLYHCA--AYNCAISVICCVFNELKFYQGFLFN-EKPEKNMLIFENLIDLKRCYTFPIEVEVPMERKKKYMEIRKEA------RETANGNSDGPHYMSSLSYLADSSLSEEMSQFD--FSTGVQSYSYSSQDPKSTTGHFRRREHQDPKIQEDVLELEMDELNQHECMAPMVALIRHMQRNLIPLREEEGSVPKDLPPWMKFLHDKLGNSSVPLNIRLFLAKLIINTEEVFRPYAKNWLSPLLQLVVSENNGGEGIHYMVVEIVATVLSWTGL-ATPIGVPKDEVLANRLLHFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSSQDPNSKDNSIGIQLLGIVMANNLPPYDPKCGIESIKYFQALVNNMSFVKYKEVYAAAAEVLGLILQYGTERKNVLEESVCEL---VVKQLKQHQNTMEDKFIVCLNKAVKGFPPLADRFLNAVFFLLPKFHGVMKTLCLEVVLC---RAEEITDLYLQLKSKDFIQVMRHRDDERQKVCLDIIHKMLAKLKPVELRELLNP-VVEFVSHPSPICREQMYNILMWIHDNYRDPESQTDDDSQELF-KLAKDVLIQGLIDENLGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTSMSPDYPNPMFE-HPLSECTFQEYTIDPDWRFRSTVLTPMFIETQASPSTLQTRTQEGFLPAQWPKAGQVRATQQQYDFT--------PTQTSDGRS-----SFNWLTGSSIDPMADYTISSSSDSLSSSLLFANKRKEKSQRAPWKSVGPDFGGKRLSLPGDEMDNKVKDGTDSRAEILKLRRRFLKDQEKLSLMYAKKGLDEQKREKDIKSEL---------KMKQDARVVLYRSYRHGDLPDIQIQHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKMMSEKNNITQNLLQDFNRFLNTTFFSFPPFVSCIQEISCQHADFLSLDPA-----------AVRASCLASLQQPGGIRLLEEALLHLAPAEPL--NKRSRGKTCLPPDILRWMELAKLYRSIGEYDVLRAI-----FSSEIGTKQVTQNALLAEARNDYSEAAKQYNEALNRQEWEDGEPTEAEKDFWELAS---LDCYSHLSEWNSLEYCSTACVDSELSKMWSEPLYQEMF--LPYMIRSKLKLLL--RGEGNQSLLTFMDEAMHQ-ELQQAFIELQYSQELSLLYILQDDFDRAKYYVENGIQIFMQ---NYSSIDVLLHRSRLTKLQSVQALTEIQEFISFITKQDNLSSQVPLQRLLKTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLIPVSDDTSMSVDEDEYSSDNREVSKPEESVGFLIKNCRFSMKMKMIESARKQNNFSLAMKLLKELHKESKTRD-NWQIKWVHSYCRLSHCRSHT--------QTPPEQILTVLKTVSLL------DENSTSSYLSRNSLASCDQNILLGTTCRIMANALSSEPVCLADIGESKA-KRILELSGSSAENV-ERVVMGLYQRAFLHLSKAVRTAEETQSFSWGHGPAAGVIDSYMTLVNFCDQQLHKAEENASVIDSVELQEYPAIV---VEKMLKALKLNSTEARLKFPRLLQIIEQYPEETL--NLMTKEISSIPCWQFIGWISHMVALLDKEEAVAVQHTVEEIASSYPQAIVYPFIISSESYSFKDTSAGHKNKQFVARIKNMLDQGGVIQDFINALDQLSNPDLLFKDWVAEIKDELEKSPVN---KKKIEKLYEKMY-AALGDPRAPGLGPFRRRFIQAFGKEFDEHFGKKGSKLPRMKLSDFNDITNTL---LLKMRRDTKPPGNLKECSPWMSEFKVE--------FLRNELEIPGQYDG-RGKPLPEYHARISGFDERVKVMASIRKPKRIIIRGHDEREYPFLVKGGEDLRQDQRIEQLFEVMNVILSQDSACSQRNMQL---RTYRVVPMTSRLGLIEWIENTFTLKDFLLNNMSQEEKMAYLSDSKAPVMEYKDWLKKMSGKQDAGAYALMYKRANRTETVMAFRKRESKVPA-SLLKRAFMKMSTGPEAFLALRSHFASSHALLCVSHWLLGIGDRHLNNFLITMETGSMIGIDFGHAFGSATQFLPVPELVPFRLTRQFINLLLPMKEMGLMYSVMIHALRAFRAEADLLINTMDVFVREPSFDWKNFEQKMLKKGGSWIQEINITKKNWYPQQKICYAKRKLAGANPAVITCDELLLGHEKFPAFGDYTAVARGSKDHNIRAREPDSGLSEETQVKCLIDQATDPNILGRTWEGWEP 4043 HSP 2 Score: 227.254 bits (578), Expect = 6.621e-55 Identity = 276/1173 (23.53%), Postives = 528/1173 (45.01%), Query Frame = 2
Query: 383 EKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQLQNKSST--TVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLK-ILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQ-EQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV-----PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAAL-STRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLL-----YKSEDVNNEKIN------TDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ----INLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERW-IKAFPHM-GSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIE--NIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDV--SKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDL 3751
+K++P+ IK+ + V +K +AK K +L IK LQ + + + F+ IG + + +L +K+ TVL + EL+G + ++P+ ++S + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ LK I R+A + L T H + + + +F + K +H NV LK +A + L+ +L+ QI F + + +Y QF ++ S +K L I+G G C V+ K+ + +Y + + + +L + D + +P + + IA +L+ L + + +L++ +I + F ++SP++ ++F A+ + + + I +V+QA+I CS PV S Q S + ++ + T + DL + DF+ L N + L++D F+K KI+++LDL + ++ NE +DP + PKDF F+NL + + + + W L+ +S LPL+SGFYK++ ++ +F+ +L+C+ + C A+F + K+ Y DELL +CLT +++ P I ++ + P LQMA +LG Y PL + L+ LE W + H+ + K ILP L S +S + + + L A++G K+ L+ ++ +++ +N + LE+++ R+++ILG +G ++ LI + + W++ E + + +PF+D+KP I L+ + ++ LAL+++ Q K A E+LHS+++ +LGK AT + + + + + + F + ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD GQ + FLK S + VN K +R+Y + S +KRLGA FN+I+ + + L++ +F + +E L+ D K LGTI Q A I + R ++ K + + +K R +P P+ T+ + ++WLL + + R I+L
Sbjct: 98 QKIMPYAFDIKS-ICTSVYTKDRAAKCKIPALDLLIKLLQTLRSSRLMDEFK--IGELFNKFYGELASKAKVPDTVLEKVYELLGVLGEVHPSEMINHSDNLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE--DPQTSREIFDFALKAICPQIDLKRYAVPLAGLRLFTLHASQFSTCLLENYISLFEVLSKWCSHMNVELKKAAYSALESFLK------QISFMVAKDAEVHKSKLQYFMEQFYGIIRNTDS-----NNKELSIAIRGYGLFAGPCKVINAKD-VDFMYIELIQRCKQMFLTQTDTVDDHVYQMPSF-LQSIASVLLYLDTVPEVYTP-----VLEH-----IIVVQIDCFPQYSPKMQSVCCKAIVKVFLALAEK----GPILWNCISTVVHQALIRICSKPVILQKGADSESKDQRASGEVRTGKWKVPTYKDYVDLFRHLLNCDQMMDFILADETFLFVNSSFQSLNHLLYDEFVKSILKIVEKLDLTLEKQTFGEQEDGNETTGVWVIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQVGFFEPWMYSFAYKLILQSTRLPLISGFYKLLSIAVRNAKKIKYFEGVSPKSLKCSPEDPEKYSCF-ALFAKFGKEVSV---KMKQYKDELLASCLTFVLSLPHDIIELDFRAYVP-------ALQMAFKLGLSYPPLAEVGLNALEEWSVYIDKHIIQPYYKNILPCLDGYLKTSTLSDEAKNNWEVSALSR--AAQKGFNKV--VLKHLK-----------KTKNTSSNEILSLEEIRIRVVQILGSLGGQINKNLITATTSDEMMKKCVAWDR--EKRLSFAVPFRDMKPVIYLDIFLPRVTELALSASDRQTKVAACELLHSMVMFMLGK-ATQMPEGDQGSPPMYQLYKHTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGI-------------VDPIDSTL-RDFCGQCIREFLKWSIKQTTPQQQEKSPVN--TKSLFKRLYSFALHPSAFKRLGASLAFNNIYREFREEESLVDQFVFEALVIYMESLALAHADEKSLGTIQQCCDA---IDHLTRIIEKKHISLNKAKKRRLPRGFPASTSLCLLDLVKWLLAHCGRPQTECRHKSIEL 1190
BLAST of DNA-dependent protein kinase catalytic subunit vs. TrEMBL
Match: I3MEE6 (Protein kinase, DNA-activated, catalytic subunit OS=Ictidomys tridecemlineatus OX=43179 GN=PRKDC PE=3 SV=2) HSP 1 Score: 546.969 bits (1408), Expect = 8.125e-152 Identity = 627/2644 (23.71%), Postives = 1136/2644 (42.97%), Query Frame = 2
Query: 4820 NWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNIC----ENNF--IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENI-KTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENII--WFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVN----LKIISTIYTSLGPFCNQDKVGLREKK---------------LIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYTNLLLRYNKP-----LFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNS---NLMDSDSFLQHDGRCLM--------IINIPYDIVNDHPCMDTFICL-HHQMKNVGII--SEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILK---MSSINPFVESVLRLIIDWSSVPGVYDKVSKANI--NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDI---LFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNM---PQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEW--SSSQIPGVDMSLSI-----------------KSQKS--------FLNLSTSVMHIENEDKASNQQENQTEFQTINK-------TIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIP-------YLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKADCFGXXXXXXXX--XXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELT--------KFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYS----LSSEADTLMLQSLHFLNEICQFLQAVQKCD-----MPIDYISKLKGNQ-GDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISD---------------------------LQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKV-HLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLL--SLGDC-----YWTLGNVLSLHWQSEP-------ENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESD------GNKKELSAALVVVSDFYDAQIRQFENDGP--------SRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYF---------PNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HRMSRMSKQSIET--------FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFK--------------CMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEP 12088
NW + D S++ + + + LL +++ IDS++ N+F +F + +LL+ + L + K + + + F T G S + ++++ + NF S + Y++ + L++ ++ ++ I CRE H E+ + T + + R ++ LL + N+ F+++ ++ C + L FF + ++ + + F NE I K++ IY+ L +D V +E K L +L K+C + L + +Y+ A+NC SV+ ++ KFY L KP +F ++I FP E+ + ++ K+ + KE + +++ P + S +L+DSSL+ ++ + + S V S + D S H R ++ + D +N H CM + L H +N+ + E + D+P WMK HD ++I+ F+ KLIIN +F+PYA W+ L++ ++ + I+ V ++ ++ W+ + V K + N L+++L ++ + ++ R N+E+ +L+ WK+ + IPY+ IF+ + + N G+++L V+ N + + LV + K V+ A E+ G++L+ + + E V E+ + + + + F+ CL K + R ++ + +L LE++ C + E +L+ QL + + ++++ + + H+ + + + +N VV+ P + + + D S+ D LF + L+ G ID + + IRNF S LP+ TL+R + + P+ I V+ FL++ATN +LEMTS PD+ P+F+ H S TF+ T + L P F+ P L++ + + P + + + +D+ P+Q + + S W SS P D ++S KSQ++ F S+ E ++K + +++ E + + + Y K+ ++ REK ++ + K +++ V LYR+Y G LP+I+IQ+ S I PLQ +AQ + +K LF L++G+LKE + F QNL Q F+ L T + +S +I+ + ++L+P+ V A+ L G ++ + + PA+ L ++ + G + +P L KLY+ + + + + SS + + AL A+ +Y+ + E E E E + ++ +D L +W L L+ M E L + F ++ SKL+ L+ + ++ +DE + + ++ EL E+SL YI+++D+++A+ + E + +YS L + LQS+ L EI +F+ + K D +P+ + K N+ D + + + W++++ R +L K K +++ + + + ++M+ I++ N S A LK ++S D N ++ W Y ++ H RS PE ++ + +V LL D N + YL SL C T +++ SEP E+K ILEL + + + ++ GL ++F +K + E+ G + + + + +F D Q+ + E + P ++ VE L ++KL A+ KFPRLLQII Q+ + N +T SSIP W +I W+ M+ LD + V+ + IA YP A+ YPF++ Y TS + F+ +I +L ++ F AL Q+ P+ + W+ E D + + ++ I Y+ MY +G+ G F+ F + F + ++F + G+ + + + F++I N + L + NLK+ SPW++++ ++ LEIPGQY+ +P PE H +I + +++M S + PK+III G +E+ Y FLVK GEDLRQD RIEQ+F VMN I+S+D ++ L +TY V+P++ LGL+EWI+NT TL +F M EE+ Y S +Y + AY +++++ T F + ++ + LL+++FM +S E+F LR +F +A+ +H+LLGIGDRHL NFLI TG +IGIDFG+AFG AT FLP+PEL+PFRLT + L P G+ + + L E +++ M VF+ DW +M + I+ + Q++I + RKL +P ++ +EL + + K F + S +E +Q K L+ AT+ L RTW+G+EP
Sbjct: 1626 NWRKCD--SWWAKDSAPESKMAVLALLTKVLQIDSSVSFNTNHNSFPEVFTTYTSLLADSELGLHLKGQAVILLPFF----TSLTGDSLEDLKHVLEMLIVSNFPMNSNEFPPGTLRYNNYVDCMKKFLDALEL-----SQSPILLQLMTDILCREQQHVMEELFQATFKRIARRNSCATQLGLLESVYRMFRRDDLLSNVTRQAFVDRSLLTLLWHCSLDALKEFFSKIVVDAIDVLN-SRFTKLNEATFDTQITKKMCYYKMLDVIYSRLP----KDVVHSKESKINQVFHGSCITEGNELTKKLIKLCHGAFTENMAGESQLLERRRLYHCA--AYNCAISVICCVFNELKFYQGFLFN-EKPEKNMLIFENLIDLKRCYTFPIEVEVPMERKKKYMEIRKEA------RETANGNSDGPHYMSSLSYLADSSLSEEMSQFD--FSTGVQSYSYSSQDPKSTTGHFRRREHQDPKIQEDVLELEMDELNQHECMAPMVALIRHMQRNLIPLREEEGSVPKDLPPWMKFLHDKLGNSSVPLNIRLFLAKLIINTEEVFRPYAKNWLSPLLQLVVSENNGGEGIHYMVVEIVATVLSWTGL-ATPIGVPKDEVLANRLLHFLMKHVFHPKRAVFRHNLEIIKTLVECWKDCLSIPYRLIFEKFSSQDPNSKDNSIGIQLLGIVMANNLPPYDPKCGIESIKYFQALVNNMSFVKYKEVYAAAAEVLGLILQYGTERKNVLEESVCEL---VVKQLKQHQNTMEDKFIVCLNKAVKGFPPLADRFLNAVFFLLPKFHGVMKTLCLEVVLC---RAEEITDLYLQLKSKDFIQVMRHRDDERQKVCLDIIHKMLAKLKPVELRELLNP-VVEFVSHPSPICREQMYNILMWIHDNYRDPESQTDDDSQELF-KLAKDVLIQGLIDENLGLQLIIRNFWSHETRLPSNTLDRLLALNSLYSPK----IEVH-------FLSLATNFLLEMTSMSPDYPNPMFE-HPLSECTFQEYTIDPDWRFRSTVLTPMFIETQASPSTLQTRTQEGFLPAQWPKAGQVRATQQQYDFT--------PTQTSDGRS-----SFNWLTGSSIDPMADYTISSSSDSLSSSLLFANKRKEKSQRAPWKSVGPDFGGKRLSLPGDEMDNKVKDGTDSRAEILKLRRRFLKDQEKLSLMYAKKGLDEQKREKDIKSEL---------KMKQDARVVLYRSYRHGDLPDIQIQHSSLITPLQAVAQRDPIIAKQLFSSLFSGILKEMDKFKMMSEKNNITQNLLQDFNRFLNTTFFSFPPFVSCIQEISCQHADFLSLDPA-----------AVRASCLASLQQPGGIRLLEEALLHLAPAEPL--NKRSRGKTCLPPDILRWMELAKLYRSIGEYDVLRAI-----FSSEIGTKQVTQNALLAEARNDYSEAAKQYNEALNRQEWEDGEPTEAEKDFWELAS---LDCYSHLSEWNSLEYCSTACVDSELSKMWSEPLYQEMF--LPYMIRSKLKLLL--RGEGNQSLLTFMDEAMHQ-ELQQAFIELQYSQELSLLYILQDDFDRAKYYVENGIQIFMQ---NYSSIDVLLHRSRLTKLQSVQALTEIQEFISFITKQDNLSSQVPLQRLLKTWTNRYPDAKMDPMNIWDDIITNRCFFLSKIEEKLIPVSDDTSMSVDEDEYSSDNREVSKPEESVGFLIKNCRFSMKMKMIESARKQNNFSLAMKLLKELHKESKTRD-NWQIKWVHSYCRLSHCRSHT--------QTPPEQILTVLKTVSLL------DENSTSSYLSRNSLASCDQNILLGTTCRIMANALSSEPVCLADIGESKA-KRILELSGSSAENV-ERVVMGLYQRAFLHLSKAVRTAEETQSFSWGHGPAAGVIDSYMTLVNFCDQQLHKAEENASVIDSVELQEYPAIV---VEKMLKALKLNSTEARLKFPRLLQIIEQYPEETL--NLMTKEISSIPCWQFIGWISHMVALLDKEEAVAVQHTVEEIASSYPQAIVYPFIISSESYSFKDTSAGHKNKQFVARIKNMLDQGGVIQDFINALDQLSNPDLLFKDWVAEIKDELEKSPVN---KKKIEKLYEKMY-AALGDPRAPGLGPFRRRFIQAFGKEFDEHFGKKGSKLPRMKLSDFNDITNTL---LLKMRRDTKPPGNLKECSPWMSEFKVE--------FLRNELEIPGQYDG-RGKPLPEYHARISGFDERVKVMASIRKPKRIIIRGHDEREYPFLVKGGEDLRQDQRIEQLFEVMNVILSQDSACSQRNMQL---RTYRVVPMTSRLGLIEWIENTFTLKDFLLNNMSQEEKMAYLSDSKAPVMEYKDWLKKMSGKQDAGAYALMYKRANRTETVMAFRKRESKVPA-SLLKRAFMKMSTGPEAFLALRSHFASSHALLCVSHWLLGIGDRHLNNFLITMETGSMIGIDFGHAFGSATQFLPVPELVPFRLTRQFINLLLPMKEMGLMYSVMIHALRAFRAEADLLINTMDVFVREPSFDWKNFEQKMLKKGGSWIQEINITKKNWYPQQKICYAKRKLAGANPAVITCDELLLGHEKFPAFGDYTAVARGSKDHNIRAREPDSGLSEETQVKCLIDQATDPNILGRTWEGWEP 4128 HSP 2 Score: 226.868 bits (577), Expect = 7.375e-55 Identity = 276/1173 (23.53%), Postives = 528/1173 (45.01%), Query Frame = 2
Query: 383 EKLLPFCGLIKNYLMNIVKSKKSSAKMK----ELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQLQNKSST--TVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLK-ILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQ-EQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV-----PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAAL-STRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLL-----YKSEDVNNEKIN------TDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ----INLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPI-FIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERW-IKAFPHM-GSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNS--RYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIE--NIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDV--SKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDL 3751
+K++P+ IK+ + V +K +AK K +L IK LQ + + + F+ IG + + +L +K+ TVL + EL+G + ++P+ ++S + L L+ ++ ++ K +++GC +GL F K++ E ++ I+ LK I R+A + L T H + + + +F + K +H NV LK +A + L+ +L+ QI F + + +Y QF ++ S +K L I+G G C V+ K+ + +Y + + + +L + D + +P + + IA +L+ L + + +L++ +I + F ++SP++ ++F A+ + + + I +V+QA+I CS PV S Q S + ++ + T + DL + DF+ L N + L++D F+K KI+++LDL + ++ NE +DP + PKDF F+NL + + + + W L+ +S LPL+SGFYK++ ++ +F+ +L+C+ + C A+F + K+ Y DELL +CLT +++ P I ++ + P LQMA +LG Y PL + L+ LE W + H+ + K ILP L S +S + + + L A++G K+ L+ ++ +++ +N + LE+++ R+++ILG +G ++ LI + + W++ E + + +PF+D+KP I L+ + ++ LAL+++ Q K A E+LHS+++ +LGK AT + + + + + + F + ++LA D+++V++ L+ L+MQ+ +WF+ ++ +++ D + +DP + RD GQ + FLK S + VN K +R+Y + S +KRLGA FN+I+ + + L++ +F + +E L+ D K LGTI Q A I + R ++ K + + +K R +P P+ T+ + ++WLL + + R I+L
Sbjct: 98 QKIMPYAFDIKS-ICTSVYTKDRAAKCKIPALDLLIKLLQTLRSSRLMDEFK--IGELFNKFYGELASKAKVPDTVLEKVYELLGVLGEVHPSEMINHSDNLFRAFLGELKTQMTSAVREPKLPVLAGCLKGLSSLLCNFTKSMEE--DPQTSREIFDFALKAICPQIDLKRYAVPLAGLRLFTLHASQFSTCLLENYISLFEVLSKWCSHMNVELKKAAYSALESFLK------QISFMVAKDAEVHKSKLQYFMEQFYGIIRNTDS-----NNKELSIAIRGYGLFAGPCKVINAKD-VDFMYIELIQRCKQMFLTQTDTVDDHVYQMPSF-LQSIASVLLYLDTVPEVYTP-----VLEH-----IIVVQIDCFPQYSPKMQSVCCKAIVKVFLALAEK----GPILWNCISTVVHQALIRICSKPVILQKGADSESKDQRASGEVRTGKWKVPTYKDYVDLFRHLLNCDQMMDFILADETFLFVNSSFQSLNHLLYDEFVKSILKIVEKLDLTLEKQTFGEQEDGNETTGVWVIPTSDPAANLHPAKPKDFSAFINLVEFCREILPEKQVGFFEPWMYSFAYKLILQSTRLPLISGFYKLLSIAVRNAKKIKYFEGVSPKSLKCSPEDPEKYSCF-ALFAKFGKEVSV---KMKQYKDELLASCLTFVLSLPHDIIELDFRAYVP-------ALQMAFKLGLSYPPLAEVGLNALEEWSVYIDKHIIQPYYKNILPCLDGYLKTSTLSDEAKNNWEVSALSR--AAQKGFNKV--VLKHLK-----------KTKNTSSNEILSLEEIRIRVVQILGSLGGQINKNLITATTSDEMMKKCVAWDR--EKRLSFAVPFRDMKPVIYLDIFLPRVTELALSASDRQTKVAACELLHSMVMFMLGK-ATQMPEGDQGSPPMYQLYKHTFPVLLRLACDVDQVTRQLYEPLVMQLIHWFTNNKKFESQDTVALLETILDGI-------------VDPIDSTL-RDFCGQCIREFLKWSIKQTTPQQQEKSPVN--TKSLFKRLYSFALHPSAFKRLGASLAFNNIYREFREEESLVDQFVFEALVIYMESLALAHADEKSLGTIQQCCDA---IDHLTRIIEKKHISLNKAKKRRLPRGFPASTSLCLLDLVKWLLAHCGRPQTECRHKSIEL 1190
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-030131-9008]) HSP 1 Score: 375.555 bits (963), Expect = 2.676e-103 Identity = 228/750 (30.40%), Postives = 388/750 (51.73%), Query Frame = 2
Query: 9983 YSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRS----YVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVT--------SKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRK---GQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAA-------YTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMS------------RMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAETS-----QTKKLVSMATNSGFLARTWQGFEP 12088
+S + + A + +++F D ++R+ E G +++ V+ L ++KL A+ +FPRLLQ++ ++ + D + S+P W I W+ QM+ LD P + V+ ++ IA+ YP AL YPFM+ T F+ K+ L ++ +F AL Q+ PE + WLDE + S D +D+Y ++ +L + G F+++F + F +++ F G+ +Y +++ E +++ + + E NLK++SPWL+ NFR + + LE+PGQY+ ++P PE H KI + +++M S + PK++I+ GD+E+ + FLVK GEDLRQD RIEQ+F VMN I+S+D ++ ++L ++TY VIP++ +GL+EW++NT TL +F ++EQ + +E Y + A Y + + K++ T F++ + + DLLR++F+ +S E+F LR +F +A+ + ++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT V ++P G+ + + L + +++ M VF+ LDW + + Q I + +++N + RKL+ +P ++ EEL++ + K+ FK M N ++ E Q L+ AT++ L R W G+EP
Sbjct: 3356 FSRKHADTLGIVEAYMTLANFCDHRLREDEQKGEGISQQLQTLPAHVVKMMLKALKLGSEEARLRFPRLLQLVELYSKETLDLMAREVV--SVPCWQLIGWISQMMALLDKPEAVAVQHVLEEIAECYPQALVYPFMISSESYTFEESASGHRNQEFVEKLKSTLDKGGVIKEFVDALQQLTNPEMLFKDWLDEVKNQLEKPSVDKKV-------LRDLYGEMSASLGDSKAPGFGSFRKKFVQRFSKEVEKLFGPGGSKLYEKRKDK--EYLKKVDELAMSMRGFQKEPGNLKEYSPWLS--NFRVETLRSE------LEVPGQYDG-RSKPLPEYHAKITGFDERVKVMTSIRRPKRLIVRGDDEKDHPFLVKGGEDLRQDQRIEQLFGVMNIILSQDAACSQ--RSL-MLRTYQVIPMTSRIGLIEWMENTCTLKDFLASRRTEKEQKTITR-PNEIYDAWISKAAGKSEGIMRYAEVYRKANRTDTVNNFKKIEQTVPE-DLLRRAFVRMSTTPEAFLSLRSHFASSHALLCISQWVLGIGDRHLSNFMINTETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFVNLMRPMAESGLIRSVMVHSLRAYRDDPELLLNTMDVFVKEPSLDWKNFAVKQLKKGGTWTESVDTQEINWYPLQKVNFARRKLEGANPAVITSEELRLGFEKAAAFKGMLAVARGSEEHNIRARLGEKDLSVEHQVDCLIDQATDANLLGRVWVGWEP 4080 HSP 2 Score: 248.44 bits (633), Expect = 9.598e-65 Identity = 307/1319 (23.28%), Postives = 559/1319 (42.38%), Query Frame = 2
Query: 302 SNNETKVYQIFIENFCDFIINLVKFAKEKLLPFCGLIKNYLMN------IVKSKKSSAKMKELSIKSLQDILTLTGNNNF--EMNIGVCLSDLFSQL--QNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLRR----FYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSV-LPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKS--YAALSTRDFLQFWNAILQSNDDKDEC----------------SVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEK---------INTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVN-SPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEM-------ATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLI-----RDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTW----SYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDL-SEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIP-------PSPVNAIF-WMNTLEASVQSFCWLLSMNLIDAYNYFTKG-VSNLFTAVNNFL 4027
SN+E + ++ I N L F ++ + G KNY ++ +V +K +AK + +++ L +L T +++ + IG + + +L +NK TVL + EL+G + ++P+ + S L L+ ++ ++ K +++GC G+ F K++ E P + LL L R+A + L H + + +F + K H N +K ++ + L+ +L+ Q+ A N + H+ + ++ +F + ++ M S ++K L I+G G C + P++ + ++Y+ + + + YL E D++ LP + + IA +L+ L + + S V+ RL V I+ P+ Y R ++ + A V S +V+Q +I CS PV +QD +S E+ L++S + S D+L + +L + KD + L++D+ ++ KI+++LDL + + ++E ++DP + PKDF F+NL + N +W + L+ +S+ PLVSGFYK++ + I +FQ E K + A F + + +I Y DELL CLT +++ P + ++ + P LQ A++LG + PL A LD LE W P +I P Y +L + ++ N + M TAK + + M+++++ R ES I ++ R++++LG +G +R L+ D + F + W+ E + + +PFKDIKP I L+ + I+ LAL+S+ Q K A E+LHS+++ ++GK + E P +F + ++LA D+++V++ LF L+MQ+ +WF ++N E DTV + E H + +DP + RD + + + F+K S K +K +K +RIY L + + +KRLGA FNSI+ + + L+E +F ++ VE L+ +D K LGT+ Q A ++ + L + S R +P P + + WLL + R C++L E + + +P + + + + ++ + E L P P V A WM+ L A++ + + LI G S+ AV FL
Sbjct: 78 SNDELRDARVDIFNL------LGTFLQKMSVGVKGWEKNYAVDLKDVCLVVYTKDKAAKCRGPALELLIKVLYATKDSSVSQDFKIGDMFNKFYGELSQKNKLPDTVLGNIYELLGVLGEVHPSEMVNNSDKLYKAYLGELKGQMTSNTKEPKLPVVAGCLRGITALMVNFTKSMEEGRWKFIIPFMKLLFFIFLLQTEMKRYAVTFAGLKLFAKHAGQFSSCLMDHYRTVFDVMSKLCGHINAEMKKTSYSALESFLK----QVAFLVAEN-VEKHQSK-LKFFMQKFCSIIRTMDS-----SNKELSIAIRGYGFFAAPCKAVCPQD-VDLMYTELIQRCKQMYLTESDRDDDNVYQLPSF-LDSIASVLVHLDRVPEVYTS--------------VLERLLVVQIDTYPQYSQRMQYATCRSIIKVLMAMAAKGPVLWSFTSSVVHQGLIRVCSKPV------VQD--------------ESGESSLVRSGKWKLPSCNDYLDLFKVLLDCENMKDPGLLDGFVASTSYSLKALNKLLYDALVQSIMKIVEKLDLSVQKVNADDEGQSDLSAGLIPSSDPTTNLMPNKPKDFTAFINLVDFCSKLLPSKNPEYFAQWMYPLCHELILQSIRFPLVSGFYKLLALCMNIAKKIKYFQD--EGPKSTNEGSPAGRACFALVSKFGKEVCVRIKQYKDELLAACLTFVLSLHPDMVALDIKAYIP-------ALQAALRLGLSHAPLATAALDALESWSSHIP-----FPIIQPHYADIL--PHLDGYLKTAANTGKAGSMNITFVSSGTAKGYGQVM------MRLLKKSRHLPGDESPI---------AAVRRRVVQLLGHLGGQLNRSLVTAISAEDMMKQF---VAWDS--EKRLSFAVPFKDIKPVIYLDPFLPRITELALSSSDRQTKVAACELLHSVVVYMVGK---GVQMTEGETSTPPMYNLHKRVFPVLLRLACDVDQVARQLFEPLVMQLIHWF-----TNNKKFE-----SQDTVAVL--EAILHGV-VDPLDSTL-RDFSSRCIQEFVKWSI--KQTTPKQQEKSPANMKSLFKRIYSLALHPNVFKRLGAALAFNSIYRHFREENSLVEQFVFEVLVVFVESLALAHSDEKSLGTVQQCCSALDHLKRIVKHKADSLNNKSTKRRIPRGFPPEQPVLLCDVVMWLLTQCGRPQTECRHKCMELFYEFVPLLPGKPSPAQWLEEQVKKEGQRFLITRLEGGGLLSQPTLREVEAPFSVRAALQWMDLLLAALDCYNTFTGLRLIQPQKILDSGEKSSFLPAVRFFL 1288 HSP 3 Score: 167.548 bits (423), Expect = 2.284e-40 Identity = 234/1123 (20.84%), Postives = 456/1123 (40.61%), Query Frame = 2
Query: 4784 TEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLL-ALFED-ELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKIN---NFENPNERELQNVIVNLKIISTIYTSLGP-------------FCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSW----AFNCFSSVVIATQSDEKFYTNLLL----RYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDG-----RCLMI-----INIPYDIVNDHPCMDTFICLHHQMKNVGI---ISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKANI------NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTN---GYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSD----FVTCLALIGKNHSDIICRQISNLMSILKSLTD--NDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQ--AITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSS--EKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGV 7945
T+ + + L W + P+ + P + + + LL +++ IDS++C + IF F L++ T L + K++ + + F K + G ++ + + +F S + Y++ + L++ ++ ++ + CR+ H ED + Q + + E ++ LL +FE + K + +I L++ + C + L+ FF + + ++ ++ E+ E ++ I K++ +Y+ L FC K ELSK +L+ C + N + +R A+NC +++ + ++ KFY L N+ +F +++ +FP E+ + ++ K+ + KE S + P++ S +++DSSL+ ++ + + S V S S + H G R M+ + + D +N H CM T L M+ I + E SD+P WMK H ++I+ FI KLIIN +F+PYA W+ L++ ++ I+ V ++ ++ W+ V K N N LI +L +NC+ ++ R N+E+ +++ WK+ + IPY IF+ + N GL++L VL N Y G ++D F + + + K ++ A E+ G+ L +KD + +++ L + T + K D FV CL+ + ++ ++ + ++ +L L +C L C + ++ ++F L + + ++ + + + H+ A+ E K + V P + + + D S + + +N + LL G D ++ + +RNF S + LP TLER +L L+ S I +FL++AT+++LEMTS PD+ + +F+ L S F++ T ++ LRS V T + + QA Q A + + + + + S+E+S +Q PG
Sbjct: 1606 TQGSRLAEQLLKGWDFLKPW-WGIPASSPESKTSILTLLSKVLQIDSSVCSDINHPAFTAIFSTFTTLITDTALPLNLKSQALIILPFFTKLPS---GPLEELQGALNSLVVAHFPMQSDEFPRGSLQCNNYMDCVRKFLDALEL-----SQSPVLLKLMAKVLCRDKKHIMEDNFQTCFQRIARQSTCEGQVLLLCTIFEMFQTKDVPMNSMLIGLLDRVLIPLTTHCSPKALSQFFITNVATIMTTLQARFSKVVESAFESQIITKIGCCKLLELLYSRLPKEEVYSKDSAINQVFCGPVKAE------GNELSK--NLLKSCFEGFTENMAGETALLELRRQYHCSAYNCAIALISCSFNETKFYQGFLFTEKAEKNQFIFENLVDTQRTYSFPIEIDVPIERKKKYVMIRKE---------VSGENGDAPVYLSSQSYMADSSLSEEMSQFD--FSTGVQSFSYSSQNPTGHRGGRARERVEMVPQDETVELEMDELNQHECMATMTALFRHMQRNNITPKVEEGSTPSDLPPWMKFLHGKLANPSTPLNIRLFIAKLIINTEEMFRPYARHWLGPLLQLVVSGNNGGEGIHFMVVDIVVTVLSWTGV-----ATPKGNTRDEVLANRLIEFLMKNCFHSKRAVFRHNLEIIRTIVECWKDCLHIPYNLIFERFSGTDVNSKDNSVGLQLLGIVLANHLSPYDAACGIDHDRYFQSLASNLSFIR--YKEIYSAAAEIIGLTL-NYMKDREDQNQAPL-----LNATVTKLTDLKKKDLSDKFVICLSKVSRHFPPLVSQFVNTAFYLLPKLHGILKTHC-----LECVLSCADSIPDIFMHLKTKGFVQIMAHRDEARQRVCLDIVHKILAVLKPEELK---EFLGTVCAFVSHPSPVCRERMYDILMWIQDNYSDAESREDSTSVEVLNTAKDTLLQGLTDENQGLQLYVRNFWSHEKRLPPATLERMLMVLGSLY--SARI--------EERFLSLATDLLLEMTSQSPDYTRDMFEFPL-SECKFQDYT----------------IDSNWRLRS---------TVLTPMFMETQATQATGTQGADSAKSQAGSMKGQIRATQASLEFSQTQAPGA 2643
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:ZFIN;Acc:ZDB-GENE-030131-9008]) HSP 1 Score: 343.969 bits (881), Expect = 9.303e-94 Identity = 217/744 (29.17%), Postives = 363/744 (48.79%), Query Frame = 2
Query: 9983 YSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPD-----LIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVT--------SKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRK---GQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMS------------RMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCM---------KNFQSEDAETS-----QTKKLVSMATNSGFLARTWQGFEP 12088
+S + + A + +++F D ++R+ E G L V+ L ++KL A+ +FPRLLQ++ ++ + D + S+P W I W+ QM+ LD P + V+ ++ IA+ YP AL YPFM+ T F+ K+ L ++ +F AL Q+ PE + WLDE + S D +D+Y ++ +L + G F+++F + F +++ F G+ +Y +++ E +++ + + E NLK++SPWL+ NFR + + LE+PGQY+ ++P PE H KI + +++M S + PK++I+ GD+E+ + FLVK GEDLRQD RIEQ+F VMN I+S+D ++ ++L ++TY VIP++ +GL+EW++NT TL +F ++E ++F+ +S E+F LR +F +A+ + ++LGIGDRHL NF+IN TG +IGIDFG+AFG AT FLP+PEL+PFRLT V ++P G+ + + L + +++ M VF+ LDW + + Q I + +++N + RKL+ +P ++ EEL++ + K+ FK M N ++ E Q L+ AT++ L R W G+EP
Sbjct: 3120 FSRKHADTLGIVEAYMTLANFCDHRLREDEQKGEVSSSQQLQTLPAHVVKMMLKALKLGSEEARLRFPRLLQLVELYSKETLDLMAREVV--SVPCWQLIGWISQMMALLDKPEAVAVQHVLEEIAECYPQALVYPFMISSESYTFEESASGHRNQEFVEKLKSTLDKGGVIKEFVDALQQLTNPEMLFKDWLDEVKNQLEKPSVDKKV-------LRDLYGEMSASLGDSKAPGFGSFRKKFVQRFSKEVEKLFGPGGSKLYEKRKDK--EYLKKVDELAMSMRGFQKEPGNLKEYSPWLS--NFRVETLRSE------LEVPGQYDG-RSKPLPEYHAKITGFDERVKVMTSIRRPKRLIVRGDDEKDHPFLVKGGEDLRQDQRIEQLFGVMNIILSQDAACSQ--RSL-MLRTYQVIPMTSRIGLIEWMENTCTLKDFLASRRTEKE----------------------------------------------------RAFVRMSTTPEAFLSLRSHFASSHALLCISQWVLGIGDRHLSNFMINTETGGMIGIDFGHAFGSATQFLPVPELMPFRLTRQFVNLMRPMAESGLIRSVMVHSLRAYRDDPELLLNTMDVFVKEPSLDWKNFAVKQLKKGGTWTESVDTQEINWYPLQKVNFARRKLEGANPAVITSEELRLGFEKAAAFKGMLAVARGSEEHNIRARLGEKDLSVEHQVDCLIDQATDANLLGRVWVGWEP 3788 HSP 2 Score: 182.956 bits (463), Expect = 5.964e-45 Identity = 184/735 (25.03%), Postives = 317/735 (43.13%), Query Frame = 2
Query: 1901 NTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVN-SPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLL--LFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLI-----RDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTW----SYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSEND-KHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP---PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDL-SEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIP-------PSPVNAIF-WMNTLEASVQSFCWLLSMNLIDAYNYFTKG-VSNLFTAVNNFL 4027
++DP + PKDF F+NL + N +W + L+ +S+ PLVSGFYK++ + I +FQ+ + T G A+ +C +I Y DELL CLT +++ P + ++ + P LQ A++LG + PL A LD LE W P +I P Y +L L + + D + +L+E+ +A + + I + + ++ R++++LG +G +R L+ D + F + W+ E + + +PFKDIKP I L+ + I+ LAL+S+ Q K A E+LHS+++ ++GK + E P +F + ++LA D+++V++ LF L+MQ+ +WF ++N E DTV + E H + +DP + RD + + + F+K S K +K +K +RIY L + + +KRLGA FNSI+ + + L+E +F ++ VE L+ +D K LGT+ Q A ++ + L + S R +P P + + WLL + R C++L E + + +P + + + + ++ + E L P P V A WM+ L A++ + + LI G S+ AV FL
Sbjct: 416 SSDPTTNLMPNKPKDFTAFINLVDFCSKLLPSKNPEYFAQWMYPLCHELILQSIRFPLVSGFYKLLALCMNIAKKIKYFQVRPKSTNEGSPAGRACFALVSKFGKEVCV---RIKQYKDELLAACLTFVLSLHPDMVALDIKAYIP-------ALQAALRLGLSHAPLATAALDALESWSSHIP-----FPIIQPHYADILPHLDGYLKTAANTDRLKARLEELGSA---------------------CCALLLTYIFSQGDESPIAAVRRRVVQLLGHLGGQLNRSLVTAISAEDMMKQF---VAWDS--EKRLSFAVPFKDIKPVIYLDPFLPRITELALSSSDRQTKVAACELLHSVVVYMVGK---GVQMTEGETSTPPMYNLHKRVFPVLLRLACDVDQVARQLFEPLVMQLIHWF-----TNNKKFE-----SQDTVAVL--EAILHGV-VDPLDSTL-RDFSSRCIQEFVKWSI--KQTTPKQQEKSPANMKSLFKRIYSLALHPNVFKRLGAALAFNSIYRHFREENSLVEQFVFEVLVVFVESLALAHSDEKSLGTVQQCCSALDHLKRIVKHKADSLNNKSTKRRIPRGFPPEQPVLLCDVVMWLLTQCGRPQTECRHKCMELFYEFVPLLPGKPSPAQWLEEQVKKEGQRFLITRLEGGGLLSQPTLREVEAPFSVRAALQWMDLLLAALDCYNTFTGLRLIQPQKILDSGEKSSFLPAVRFFL 1090 HSP 3 Score: 159.073 bits (401), Expect = 8.682e-38 Identity = 228/1114 (20.47%), Postives = 452/1114 (40.57%), Query Frame = 2
Query: 4784 TEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICEN------NFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLL-ALFED-ELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKIN---NFENPNERELQNVIVNLKIISTIYTSLGP-------------FCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYTNLLL----RYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIH-SVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIP--------YDIVNDHPCMDTFICLHHQMKNVGI---ISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKANI------NLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLR-NCCGLKMLAAVLTN---GYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTD--NDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENI--QYKSSSVICAIIQLFHQ--AITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSS--EKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPG 7942
T+ + + L W + P+ + P + + + LL +++ IDS++C + IF F L++ T L + K++ + + F K + G ++ + + +F S + Y++ + L++ ++ ++ + CR+ H ED + Q + + E ++ LL +FE + K + +I L++ + C + L+ FF + + ++ ++ E+ E ++ I K++ +Y+ L FC K ELSK S + + + ++ A+NC +++ + ++ KFY L N+ +F +++ +FP E+ + ++ K+ + KE S + P++ S +++DSSL+ ++ + + S V S S + G+ + +P D +N H CM T L M+ I + E SD+P WMK H ++I+ FI KLIIN +F+PYA W+ L++ ++ I+ V ++ ++ W+ V K N N LI +L +NC+ ++ R N+E+ +++ WK+ + IPY IF+ + N GL++L VL N Y G ++D F + + + K ++ A E+ G+ L +KD + ++ +K+++ FV CL+ + ++ ++ + ++ +L L +C L C + ++ ++F L + + +Y++ +C + + H+ A+ E K + V P + + + D S + + +N + LL G D ++ + +RNF S + LP TLER +L L+ S I +FL++AT+++LEMTS PD+ + +F+ L S F++ T ++ LRS V T + + QA Q A + + + + + S+E+S +Q PG
Sbjct: 1407 TQGSRLAEQLLKGWDFLKPW-WGIPASSPESKTSILTLLSKVLQIDSSVCSDINHPAFTAIFSTFTTLITDTALPLNLKSQALIILPFFTKLPS---GPLEELQGALNSLVVAHFPMQSDEFPRGSLQCNNYMDCVRKFLDALEL-----SQSPVLLKLMAKVLCRDKKHIMEDNFQTCFQRIARQSTCEGQVLLLCTIFEMFQTKDVPMNSMLIGLLDRVLIPLTTHCSPKALSQFFITNVATIMTTLQARFSKVVESAFESQIITKIGCCKLLELLYSRLPKEEVYSKDSAINQVFCGPVKAE------GNELSKNLSCFEGFTENMAGETALLELRRQYHCSAYNCAIALISCSFNETKFYQGFLFTEKAEKNQFIFENLVDTQRTYSFPIEIDVPIERKKKYVMIRKE---------VSGENGDAPVYLSSQSYMADSSLSEEMSQFD--FSTGVQSFSYSSQNPTGRFGQKRLPNMVPQDETVELEMDELNQHECMATMTALFRHMQRNNITPKVEEGSTPSDLPPWMKFLHGKLANPSTPLNIRLFIAKLIINTEEMFRPYARHWLGPLLQLVVSGNNGGEGIHFMVVDIVVTVLSWTGV-----ATPKGNTRDEVLANRLIEFLMKNCFHSKRAVFRHNLEIIRTIVECWKDCLHIPYNLIFERFSGTDVNSKDNSVGLQLLGIVLANHLSPYDAACGIDHDRYFQSLASNLSFIR--YKEIYSAAAEIIGLTL-NYMKDREDLTDLK---KKDLS-----------DKFVICLSKVSRHFPPLVSQFVNTAFYLLPKLHGILKTHC-----LECVLSCADSIPDIFMHLKTKGFVQIMAHRYEARQRVC--LDIVHKILAVLKPEELK---EFLGTVCAFVSHPSPVCRERMYDILMWIQDNYSDAESREDSTSVEVLNTAKDTLLQGLTDENQGLQLYVRNFWSHEKRLPPATLERMLMVLGSLY--SARI--------EERFLSLATDLLLEMTSQSPDYTRDMFEFPL-SECKFQDYT----------------IDSNWRLRS---------TVLTPMFMETQATQATGTQGADSAKSQAGSMKGQIRATQASLEFSQTQAPG 2426
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: mtor (mechanistic target of rapamycin kinase [Source:NCBI gene;Acc:103042377]) HSP 1 Score: 158.688 bits (400), Expect = 1.016e-37 Identity = 140/560 (25.00%), Postives = 262/560 (46.79%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAW---LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSK-LFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ LV Q ++ + + + W L+EA+ ++ + + + + ++ + L++ F + + + L EA +D Y + N + + + W L F+ + P L + Y P ++ +D L +PG Y+ +P I+I + P +Q++ SKQ P+K+ I+G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ T EK +V FE N + DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 1901 IDTWLQV--IPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNMCEHCNTLVQQAIMVSEELIRVAILWHEMWHEGLEEASRLYFGE----RNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEA-------QDWCRKYMRSGN--------VKDLTQAWDLYYHVFRRIAKQLPQLTSLELQ--YVSPKLLMCRDLELAVPGTYD--PNQPI----IRIQSIAPSLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLAND---PASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDYDHLTL-MEKVEV------FEHAVNNTAGDDLAKLLWLK-SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDTNTKGTKRSRTR 2414
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: atr (ATR serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-070912-458]) HSP 1 Score: 137.502 bits (345), Expect = 2.442e-31 Identity = 90/326 (27.61%), Postives = 164/326 (50.31%), Query Frame = 2
Query: 10937 FPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLI--SNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQKRINISHRKLK 11908
FP + + + ++I+ S Q PKKI + G + + Y+ + K +DLR+D R+ + ++N + KD +S + I+TY VIP+++ G++EW++NT L K K++ Y+ K E P TA S +K + +++++ + + F+ S+Y R + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PE++PFRLT +MV + P G G+F Q + L + ++ +MS++ FL + +++W S+ K S++T + I + K K
Sbjct: 2077 FPGHWVYLSGFDDSVEILASLQKPKKISLRGSDGKFYTMMCKPKDDLRKDCRLMEFNCLINKCLRKD---AESRRRDLHIRTYAVIPLNEECGIIEWVNNTAGLRHILNKLYKEKGIYLTGK---ELRKMILPKTA------------SLQEKLKLHKDVLCARHPPVFHDWFLRTFPDPTSWYNSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSLTGECVHVDFNCLFNKGETF-DVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTLRLMRDQREPLMSVLKTFLHDPLVEW---SKPVKGSLKTQANESGEIVNEKAK 2380
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: atm (ATM serine/threonine kinase [Source:ZFIN;Acc:ZDB-GENE-040809-1]) HSP 1 Score: 129.798 bits (325), Expect = 5.869e-29 Identity = 82/301 (27.24%), Postives = 153/301 (50.83%), Query Frame = 2
Query: 10943 EKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFY------RLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
E + I +P + PK I +G + + LVK +DLRQD ++Q+F + + ++ ++ + K + L+ I+ Y V+P S+ G+LEW TV + EF + D ++ +K+ + +T + A K ++ + ++K + + NF + + F C E F R+ + + A + Y++G+GDRH++N LI+E T +++ ID G AF I LP PE +PFRL+ +V+ + +GV G+F + + + + Q +++I+ V L + + DW
Sbjct: 2649 EDLVTISSFKPHFHLAGGVNLPKIIDCVGSDGKSRRQLVKGQDDLRQDAVMQQVFHMCSTLLQRNAETRK--RKLN-IRRYKVVPFSQRSGVLEWCSGTVPIGEF----LVDPQKGAHKRFRPQDWT-----SLACRKKMMEAQRMEFDKKLQAFTEVCQNFRPVFRYF-----CMERFLDPAVWLEKRLAYTRSVATSSIVGYIVGLGDRHIQNILIDEQTAELVHIDLGVAFEQGKI-LPTPETVPFRLSRDIVDGMGITGVEGVFRRCCEKTMEVMRSSQEVLLTIVEVLLYDPLFDW 2931
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000007186.1 (pep scaffold:Pmarinus_7.0:GL476459:175296:202639:-1 gene:ENSPMAG00000006485.1 transcript:ENSPMAT00000007186.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 134.806 bits (338), Expect = 2.044e-31 Identity = 95/329 (28.88%), Postives = 174/329 (52.89%), Query Frame = 2
Query: 10907 GQYNN-ITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQK----FEENQNLISNF-DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
GQY + +T R F H F+L G+ + PK I G + + Y LVK +DLRQD ++Q+F + N++++ + T++ K LS I+TY V+P+S+ G+LEW T+ + + Y+ +K + +T+Y PN + +V + +++ F Q L +F + R F ++ R+++ + A + Y++G+GDRH++N LI+ N+ +++ ID G AF I LP PE +PFRLT +V+ + +GV G+F + + + + Q +++I+ V L + + DW M+ + +++T T+
Sbjct: 712 GQYPDLVTVRAF-RPH---FRLAGGVNL------PKIIDCEGSDGRTYRQLVKGRDDLRQDAVMQQVFHMCNELLAGSAE-TRTRK-LS-IRTYKVVPLSQRSGVLEWCVGTMPIGD-----------YLVQK-DTGAHTKYRPNDWPSMHCRKFMNVAAQDRRNGDLFLAYQELCHHFRPVFRHFFWERFLDPAVWFERRLSYTRSVATSSIVGYIVGLGDRHVQNILIDLNSAELVHIDLGVAFEQGRI-LPTPETVPFRLTRDIVDGMGITGVEGVFRRCCEKTMEVMRNSQEALLTIVEVLLFDPLFDW-TMNPLKALTLQTRTE 1013
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003429.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003429.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 119.783 bits (299), Expect = 1.375e-26 Identity = 82/310 (26.45%), Postives = 151/310 (48.71%), Query Frame = 2
Query: 10934 PFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMN-DIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDL------LRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIM---SIMHVFLTNQILDWHR 11833
PFP I ++++ S Q PKKI I G + + Y + K +DLR+D R+ + +++N D++ KD +S + I TY VIP+++ GL+EW++NT +L +T+ D Y T S ++ E+ ++ + L + F+ S+Y R+ + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PEL+PFRLT +MV + P G+ G+F + + + + ++ +++ S++ F+ + +++W R
Sbjct: 2276 PFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKD---AESRRRDLRICTYAVIPLNEECGLVEWVNNTESL-----RTIVD--------------ILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTF-GVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSR 2562
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003421.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003421.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 119.783 bits (299), Expect = 1.378e-26 Identity = 82/310 (26.45%), Postives = 151/310 (48.71%), Query Frame = 2
Query: 10934 PFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMN-DIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDL------LRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIM---SIMHVFLTNQILDWHR 11833
PFP I ++++ S Q PKKI I G + + Y + K +DLR+D R+ + +++N D++ KD +S + I TY VIP+++ GL+EW++NT +L +T+ D Y T S ++ E+ ++ + L + F+ S+Y R+ + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PEL+PFRLT +MV + P G+ G+F + + + + ++ +++ S++ F+ + +++W R
Sbjct: 2296 PFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKD---AESRRRDLRICTYAVIPLNEECGLVEWVNNTESL-----RTIVD--------------ILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTF-GVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSR 2582
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000003412.1 (pep scaffold:Pmarinus_7.0:GL476508:503342:564700:-1 gene:ENSPMAG00000003096.1 transcript:ENSPMAT00000003412.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 119.783 bits (299), Expect = 1.380e-26 Identity = 82/310 (26.45%), Postives = 151/310 (48.71%), Query Frame = 2
Query: 10934 PFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMN-DIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDL------LRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIM---SIMHVFLTNQILDWHR 11833
PFP I ++++ S Q PKKI I G + + Y + K +DLR+D R+ + +++N D++ KD +S + I TY VIP+++ GL+EW++NT +L +T+ D Y T S ++ E+ ++ + L + F+ S+Y R+ + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PEL+PFRLT +MV + P G+ G+F + + + + ++ +++ S++ F+ + +++W R
Sbjct: 2310 PFPGNMAYIVGFHDPVEVLSSLQKPKKICIRGSDGRSYPMMCKPKDDLRKDCRLMEFNSLINKDLLRKD---AESRRRDLRICTYAVIPLNEECGLVEWVNNTESL-----RTIVD--------------ILYNEKGIGLTMSEVSKCILPIETPLEQKLSMYRDKLLPPHPPVFHEWFLRTFPDPTSWYSSRLGYTRSTAVMSMVGYVLGLGDRHGENILFDSLTGECMHVDFNCLFNKGLTF-GVPELVPFRLTHNMVHAMGPMGLEGLFRRACEVTMRVMCDQRESLIRGASVLKTFIHDPLVEWSR 2596
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000010422.1 (pep scaffold:Pmarinus_7.0:GL478779:2292:46075:1 gene:ENSPMAG00000009431.1 transcript:ENSPMAT00000010422.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 58.5362 bits (140), Expect = 3.960e-8 Identity = 31/109 (28.44%), Postives = 55/109 (50.46%), Query Frame = 2
Query: 10958 IFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSK-DYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDE 11281
+ L P + I+P+K PKK+ + + Y++L K EDL D RI Q +++N++ K + + A + Y+V P+ GL++W+D L Y + + E
Sbjct: 2073 VHSLAPSVSILPTKTKPKKLSFLASDGNTYTYLFKGLEDLHLDERIMQFLSIVNNMFVKGNGREWHRFHA----RHYSVTPLGSRSGLIQWVDGATPLFGLYKRWQQRE 2177
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TOR1 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis; TOR1 has a paralog, TOR2, that arose from the whole genome duplication [Source:SGD;Acc:S000003827]) HSP 1 Score: 139.813 bits (351), Expect = 6.890e-33 Identity = 130/498 (26.10%), Postives = 231/498 (46.39%), Query Frame = 2
Query: 10352 YPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEA---NDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLE--IPGQYNNITARPFPEK-HIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+P AL YP + + KS + + LS ++ + + ++ +L + Q E + A ++++ D+ SRQ V + K+ L+ L K E L E + +F D Y N + + ++ INN + W + + F+ + P L + + + P +++ LE +PG Y FP K I+I K EP ++ SKQ P+K I G + + Y +++K ED+RQD + Q+F ++N ++ D ++ K I+ Y IP+S GLL W+ N+ T + +D ++ I + Q P+ T +K +V + + Q+L K S+ E++ R + + A+ Y+LG+GDRH N +++ TG +I IDFG F A + PE +PFRLT + ++ SG+ G F T +NV+ L + ++M+I+ F + ++ W
Sbjct: 1905 HPQALVYPLTVAI-----KSESVSRQKAALSIIEKI-RIHSPVL-VNQAELVSHELIRVAVLWHELWYEGLEDA-SRQFFV---EHNIEKMFSTLEPLHK-HLGNEPQTLSEVSFQKSFGRDLNDAYEWLNN-YKKSKD-INNLNQAWDIYYNVFRKITRQIPQLQTLDLQ--HVSPQLLATHDLELAVPGTY-------FPGKPTIRIAKFEPLFSVISSKQRPRKFSIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLKND---SECFKRHLDIQQYPAIPLSPKSGLLGWVPNSDTFHVLI-REHRDAKK-IPLNIEHWVMLQMAPDYENLT-LLQKIEVFTYALDNTKGQDLY-------KILWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKYPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMRVLRDNKESLMAILEAFALDPLIHW 2366
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TOR2 (PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis; TOR2 has a paralog, TOR1, that arose from the whole genome duplication [Source:SGD;Acc:S000001686]) HSP 1 Score: 138.272 bits (347), Expect = 2.018e-32 Identity = 123/503 (24.45%), Postives = 227/503 (45.13%), Query Frame = 2
Query: 10352 YPHALFYPFMLYVAD--VTSKSNFICKIGK-------ILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLE--IPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+P AL YP M+ + ++ + + I K ++ +LV + + ++Y LD+A+ F ++ + + + +Y + + LR+ FQ F + D+ D + + + + ++ N NQ W + + F+ + P L + + P ++S LE +PG + +P +KI K EP ++ SKQ P+K I G + + Y +++K ED+RQD + Q+F ++N ++ D + + + L I+ Y IP+S GLL W+ N+ T + E + I + Q P+ T +K +V + E Q+L K S+ E++ R + + A+ Y+LG+GDRH N +++ TG +I IDFG F A + PE +PFRLT + ++ SG+ G F T +NV+ L + ++M+I+ F + +++W
Sbjct: 1908 HPQALVYPLMVAIKSESLSRQKAALSIIEKMRIHSPVLVDQAELVSHELIRMAVLWHEQWY--EGLDDASRQF----FGEHNTEKMFAALEPLYEMLKRGPETLREISFQNSFGR----DLNDAYE------WLMNYKKSKDVSNL--NQ--AWDIYYNVFRKIGKQLPQLQTLELQ--HVSPKLLSAHDLELAVPGTRAS-GGKPI----VKISKFEPVFSVISSKQRPRKFCIKGSDGKDYKYVLKGHEDIRQDSLVMQLFGLVNTLLQNDAECFR--RHLD-IQQYPAIPLSPKSGLLGWVPNSDTFHVLIRE--HREAKKIPLNIEHWVMLQMAPDYDNLTL-LQKVEVFTYALNNTEGQDLY-------KVLWLKSRSSETWLERRTTYTRSLAVMSMTGYILGLGDRHPSNLMLDRITGKVIHIDFGDCFEAAILREKFPEKVPFRLTRMLTYAMEVSGIEGSFRITCENVMKVLRDNKGSLMAILEAFAFDPLINW 2370
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TEL1 (Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; acts with Red1p and Mec1p to promote interhomolog recombination by phosphorylation of Hop1; functionally redundant with Mec1p; regulates P-body formation induced by replication stress; homolog of human ataxia-telangiectasia mutated (ATM) gene [Source:SGD;Acc:S000000184]) HSP 1 Score: 115.546 bits (288), Expect = 1.760e-25 Identity = 108/428 (25.23%), Postives = 185/428 (43.22%), Query Frame = 2
Query: 10562 SNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIII--IGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSF-IKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWE---KSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
SN NI K Q + +KI+ L +G F ++ Y L +F E+ + N K NLK WL + N P S + + ARP+ I + + I + KI+ I D + + S +DLRQD +EQ+F +N ++ D K L+ L I+TY V+P+ G++E++ N+ +L + K + ++ + + A TKS E K+ + TN+ + +N FD ++ + + + A + Y+LG+GDRHL N L++ +TG+ I ID G AF + LPIPEL+PFRLT +V+ +GV G+F ++ + V L ++ + +M ++++ + + W
Sbjct: 2330 SNKDTNISQKIQAV-KKILLELQGYDRGAFAKK--------------------YLLPVQEFCEMSVELANLKFVQNTKTLRLANLKIGQYWLKQLNMEK---LPLPTSN--FTVKSSADGRKARPY------IVSVNETVGITTTGLSLPKIVTFNISDGTTQKALMKGSNDDLRQDAIMEQVFQQVNKVLQND----KVLRNLDLGIRTYKVVPLGPKAGIIEFVANSTSLHQILSK-LHTNDKITFDQARKGM-------KAVQTKSNEERLKAYLKITNEIKPQLRNFF--FDSFPDPL--------DWFEAKKTYTKGVAASSIVGYILGLGDRHLNNILLDCSTGEPIHIDLGIAFDQGKL-LPIPELVPFRLTRDIVDGFGVTGVDGLFRRSCERVYAVLRKDYVKVMCVLNILKWDPLYSW 2702
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: MEC1 (Genome integrity checkpoint protein and PI kinase superfamily member; Mec1p and Dun1p function in same pathway to regulate dNTP pools and telomere length; signal transducer required for cell cycle arrest and transcriptional responses to damaged or unreplicated DNA; facilitates replication fork progression and regulates P-body formation under replication stress; promotes interhomolog recombination by phosphorylating Hop1p; associates with shortened, dysfunctional telomeres [Source:SGD;Acc:S000000340]) HSP 1 Score: 100.908 bits (250), Expect = 3.987e-21 Identity = 80/336 (23.81%), Postives = 150/336 (44.64%), Query Frame = 2
Query: 10952 IKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYG------------KTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNF-DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQKRINISHRKLKREDP 11920
+ I + ++ S + PK++ IIG + Y + K ED+RQD + Q T M+ ++SKD K ++L I Y+V+ + + G+LE + N VTL K++ D Q+ EFY + W + NF D + +++ R + + YA+ ++LG+GDRH +N L++ TG ++ +DF F LP+PE++PFRLT ++++ L G G F ++ + L + + ++ +M+++ + ++ +D H + QK + + K++ DP
Sbjct: 2044 VSIIRFGSSYKVFSSLKKPKQLNIIGSDGNIYGIMCKK-EDVRQDNQYMQFATTMDFLLSKDIASRK--RSLG-INIYSVLSLREDCGILEMVPNVVTLRSILSTKYESLKIKYSLKSLHDRWQHTAVDGKLEFYMEQVDKFPPILYQW-----------------FLENFPDPI------------NWFNARNTYARSYAVMAMVGHILGLGDRHCENILLDIQTGKVLHVDFDCLFEKGK-RLPVPEIVPFRLTPNLLDALGIIGTEGTFKKSSEVTLALMRKNEVALMNVIETIMYDRNMD-HSI------------QKALKVLRNKIRGIDP 2332
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TRA1 (Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation [Source:SGD;Acc:S000001141]) HSP 1 Score: 61.2326 bits (147), Expect = 3.862e-9 Identity = 130/637 (20.41%), Postives = 254/637 (39.87%), Query Frame = 2
Query: 10226 LTAIFSS----IPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPF--------------MLYVADV--TSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHD---------------SNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQY-----NNITARPFPEKHIKIFKLEPGIQIMPSKQCP-KKIIIIGDNEQPYSFLVK--SGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMK-------DEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDV-VSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGID-----FGYAFGIATIF----LPIP---------ELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW----HR-------MSRMSKQSIETFTQKRINISH 11896
LT F S IP W +I ++ Q++ L +++V I+ RIA YP AL + M + D T+ N + + L L + + LL + L++ + + ND F S + + + +R K + NL + F AD DN + T I L R R+ N+L + S+ +NL+ P L+ NF ++ +EIPGQY NN+ IKI + P + + ++++I G + +SF V+ + R++ R+ Q++ + N +SK+ + + +++ F IP+S + ++ + TL E + + K D + ++ K++ AA+ + D+ + + F Q + ++L+ F ++ E F+ R F QY+ V Y++ I +R +++ +G++ ++ F Y + + L +P E +PFRLT ++ + S + GIF+ L + L + + + +F+ ++I+ W HR + M + +++ +K + H
Sbjct: 3117 LTNAFDSFRGEIPVWYWITFIPQLLTSLSHKEANMVRHILIRIAKSYPQALHFQLRTTKEDFAVIQRQTMAVMGDKPDTNDRNGRRQPWEYLQELNNILKTAYPLLALS-----LESLVAQINDRFKSTTDEDLFRLINVLLIDGTLNYNRLPFPRKNPKLPENTEKNLVKFSTTLLAPYIRPKFNADFIDNKPDYETYIKRLRY-----WRRRLENKLD----RASKKENLEVLCPHLS--NFHHQKFED-------IEIPGQYLLNKDNNV-------HFIKIARFLPTVDFVRGTHSSYRRLMIRGHDGSVHSFAVQYPAVRHSRREERMFQLYRLFNKSLSKNVETRR--RSIQF-NLPIAIPLSPQVRIMNDSVSFTTLHEIHNEFCKKKGFDPDDIQDFMADKLN-----------AAHDDALPAPDMTILKVEIFNSIQTMFVPSNVLKDHFTSLFTQFEDFWLFRKQFASQYSSFVFMSYMMMINNRTPHKIHVDKTSGNVFTLEMLPSRFPYE-RVKPLLKNHDLSLPPDSPIFHNNEPVPFRLTPNIQSLIGDSALEGIFAVNLFTISRALIEPDNELNTYLALFIRDEIISWFSNLHRPIIENPQLREMVQTNVDLIIRKVAQLGH 3708
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO34280 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPT8]) HSP 1 Score: 344.354 bits (882), Expect = 5.846e-95 Identity = 234/791 (29.58%), Postives = 395/791 (49.94%), Query Frame = 2
Query: 9926 LICGLLNKSFYCF---NKII--SMYSESDGNKKELSAALVVVSDFYDAQIRQFEN--DGPSR----------------PDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIIN--QHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFML----YVADVTSKSN----FICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRK------GQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFK----NLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLT-KSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFY--GKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSR-----------MSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFK-----CMKN------FQSEDAE---TSQTKKLVSMATNSGFLARTWQGFE 12085
++ L+ +SF NK + S SDG+ + A++ + F D +R+ E+ DGPS P+ + YV L +M+ A+N+FPRLLQI+ H LD F ++P WM+I W++QM+ +D + V I++ IA +YP AL Y F + +V D + + N + +I K+L + L+ F AAL Q+ PE + W D + ++ + Y+ ++ + + G F+++FSK + ++ F +DG + +N LKT KLK NLK++SPWL + DS+ Q LE+PGQY ++P PE H+ I + + ++ S + PK++ I GD+E+ + FLVK GED+R D RIEQ+F +MN++MS+D + ++L+ ++TY VIP+++ +GL+EW+ NT L E T +++ + ++ + S E ++ T +F++ Q + +DLLR++F ++ E++ LR +F + +A Y+LGIGDRHL NFL++ TG +IGIDFG++FG AT FLP+PEL+PFRLT L P G+ T+ +V+ L +++ M VF+ LDW +R M + + + ++++ + RKLK +P + +EL++ + + +WF+ C+ + Q E+ E +Q L+ AT+ L R W+G+E
Sbjct: 1105 IVSQLITRSFTSLQEANKAAKQAATSSSDGSTTCMVEAMMAMVPFCDRALRRKEDESDGPSFIISPFGLHYEFVFQRFPEFVVRYV---LKAMEHGSEEARNRFPRLLQIVELYPHTLDSF-----VKKVETVPCWMFIGWINQMVALMDKKEARAVHGIVTEIAKNYPQALCYAFKVSSEQFVFDSSPEGNTNRKAVERIRKLLES-PLMDSFIAALEQLHNPEMAFKDWCDGEIKQLLQTKNKKAIKEAFRSIYKQLFDSSVNRATDSSQPAAEEMGPFRKKFSKEHASRFENIFGKDGEKL--------------VNMSLKTAKLKQQMVSKPPGNLKEYSPWLTNFQA-DSHAQK-------LEVPGQYTG-QSKPMPEYHVNIAGFDEKVLVLASIRKPKRVTIRGDDERDHMFLVKGGEDIRLDQRIEQLFCMMNEVMSEDPACSQRNLR----LRTYQVIPMTQRVGLIEWLKNTKPLKELLHIAATESEKQAMVVRRKTKNMLDLTLRILFDIIISRE-ANRTDTESEFKKKQAQVP-WDLLRRAFQQLAASPEAYLTLRTHFARTHACICICQYVLGIGDRHLSNFLVDMRTGGLIGIDFGHSFGSATQFLPVPELVPFRLTRQFTNLLLPLKESGLVRNTMIHVMRALRGNHELLLNTMDVFVKEPSLDWQMFARKQAEDQHMEIGMYYEDLTWYPREKVLTAQRKLKGANPAFVTRQELELGHRRRSWFRNLQSACLGDRRHNVRAQKEENELTSEAQVDCLIDQATDVNILGRAWEGWE 1857 HSP 2 Score: 112.079 bits (279), Expect = 5.166e-24 Identity = 159/713 (22.30%), Postives = 289/713 (40.53%), Query Frame = 2
Query: 6677 NCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSD-SKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDL-SSEKPDILFVN---------CFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIF-------------------QIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQK----SFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPA--KKLKLSETNTGSSLIPY--LMKLYK 8701
N G+++L VL N + ++ + F L L K V PA E+ G+L+K ++++ ++ + +E +++ + F+TC+ + N+ I+ R + ++M L ++ + LE++ + D + LF +L + +++ V A++++ I + E S+I V S +T R L + +F+ + + + D F N + LL G D +K + ++NF S LP TLER +L ++ S N ++L+ TN+VL +TS PDF + +F Q H+ T F S + SL P + Q +S + DQ ++ FDW+ PS + + S E SS + G S +S K F + + +++ Q E + + T ++ D YF +K+++L + Q K + S V +YR Y G LP+++I++ IAPLQ +AQ + +K LF L +L + + E ++ DNI+ + I SC++ + S + + PS V AS S + + +LLEK L+ S E P K+++ + + + + L KLY+
Sbjct: 16 NATGIQLLGVVLANKIHPFSSDSSVDENTFYTALSDNLTFKYKDVHAPAAEVSGMLMKYLIEERKVTECSLIALVEAKLS-PMATKGGKDIGKFITCVHRLQLNYPRIVDRFMKHIMFHLPTIHGVFKAQCLEIVLSRVSDIPD---LFTELRSKGLNVMFEHRDEGVQVALLKI----IQGLLEKLKMSEIEYVV----PSIATMATSSSTACRELIYDIFMWVYDTYRSDETFRNEEGSEEILATAKDYLLRGLADDNKILKLKLQNFWSDETRLPNTTLERLVDVLRAMY-------STN---TEQQYLSYTTNLVLHLTSFSPDFERLMFEQPLSECKFEEYPIDYSWQQRHVVMTPLFAATQGSTQSHSQGGSLEPGALRATQLRVEFSPTMDQSL-----------SQAFDWLN-------PSSQADSVQSFTVGSSEAQSSLLFGTKPRASQRSLKPVPHDFGSRRLAPTQSDSQQATPAMGSQQQEILRLKRRF-TKDSQTKDRQYFIRMHEKKRQMLQQTQSRLKAARESQVVMYRRYRAGDLPDVQIKHSELIAPLQAVAQCDSTLAKQLFSVLVQAILSQMDEKLTEQDAEKTVTDIQGALDNIMTSSTQFYPPFI-SCIEDICYHKSMLKVQPSSVSTASLASLQQPMGILLLEKQLL---------SQEAEPKSHKRMRTEHSPSSDTTAAWLELAKLYR 677
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO34282 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SPU0]) HSP 1 Score: 213.386 bits (542), Expect = 5.261e-55 Identity = 263/1218 (21.59%), Postives = 520/1218 (42.69%), Query Frame = 2
Query: 602 LIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNSKT-----SIISGCCEGLRRFYKALPEKLS--AKSPPTIY-LLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQ---IFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSV--QNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCS-SKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPV----PPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSN----------------DDKDECSVLIFDSFMKCAYKIIDQLDLL---YKSEDVN--------NEKINTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQ--INLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPH--MGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMATAKRGSRKLARTLRSMQIIE--QQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDN-INWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTAT------TILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSE-NDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVPPSWT---AATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFE-----STELFKIPP--------SPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYF-TKGVSNLFTAVNNFL 4027
L ++G ++P + I +NLL E+ + +I+GC +GL + + + +K IY + I + R+ ++ L+ L+ H + I + ++P I + H N K++A +D +L+ + E I + A + + +E F +++ R++ + T + + I+G G K C + + E + +++ + + + YL + + ++ R + + + L +L+ I++ L S F + + RL V E PRL YL + ++ N+ A +V + + ++VYQ +I +CS PV PD D + + T S + + +D+L W +L + ++ L++D + +II +LDL + +D+ E+ +DP+ G KDF++F+NL + + + + +W L+ S P+VSGFYK++ +KI FFQ + + ++ D C + F + I +L K+ + ++LL +CL+L+++ P I + + L++ +LG YLPL QA L LE W + P + ++ ILP L + VE + +Q + AT + +L + L S+ I+ +R+ E + L ++ +++R+LG++G + + L+ + S + + W+ + + +PF+D+KP I L+ + + LA S+ Q K A E+LH+L++ +LGK T L ++N+ W + + ++LA D+ +VS LF L+MQ+ +WF+ ++P +D+ + V++ PT+ RD + Q + FL+ S K ++ L+K IK L+R+Y L + + KRLGA FNSI+ + + + L++ + ++ +E L+ +D GT +Q ++ ++ + L +K R +P + + T+ I L+ + R C+ L Q++ + + + + ++FE + P S + W + L A++ + W+ L+ + +K S LFT+++ FL
Sbjct: 8 LYTILGVFAEVFPEHMLGNADRLISIYINLLNSEMKSKGNKSPDKQVIAGCLKGLSSYLVNFTQSAAEGSKFARDIYEFTRMAIDVQGTLQRYDVPRAGLNLLSRHAGQFQEYICTEHNVSLIVYPAIYRWCCHQNRETKYAALDAMDSFLKQVSEYIVLDEAE---AVNPKEDF----------IQRFRAIIDSDSSTTQQMSIAIRGYGFFAKPCKLFMTAEDVKFMFTEMMQRSEQIYLRQSEMQEDR-------VQQLPNFLEALSFIIEELDDISDGFLV--------SLERLIIVLFESFPRLSKSAKYLCHKALVKMLINISAKGSVLKNFLSEVVYQGLIRTCSHPVLLDEGPDV-----------DKQVGVVTGSRSDQV-------TFKDYLPLWEHMLDKTKFKMYLLFQSLSLSDIEKRESLHELVYDELVGAILRIIHKLDLTSTKHGQQDLQVRDQPQEEQEETTSDPVAGLQPRVQKDFLVFINLVDFCKALLPGQSTDSFGRWVYVFGRDLIVSSSRFPVVSGFYKLLEVCMKICKRLRFFQYEVTADDMEIVDTSD-CTNC-FILFRKFIKEVLIKMKQFKEDLLSSCLSLVLSLPYEIVAVDVAA------IVPALELTFKLGLSYLPLAQAGLAALEEWNASLPGDVLRRHLRNILPYLDGYL--KSATDAVEEEQDQVS-RRTATLRSTYSRLGKIL-SLYYIDFVSKRNILPQVGE-------SSLVTIRVQILRLLGQLGGHTNLCLLGSDGGVDSGSAVAWDTVKH--LPFAVPFQDMKPTIYLDPFLPRVVELATTSSNRQTKVAACELLHTLVLYMLGKGVTQPDVKKVALPMQNL-----WKKLIPVLLQLACDVERVSAQLFHPLVMQLIHWFTNNRKYESPETIALLDALLEGVVH-PTD-------------TSLRDFSAQCIREFLQWSI--KQTSAKQLEKSPINIKSLLKRLYSLALHPNASKRLGASLAFNSIYTVFREERSLVDVFVLEILVTYLESLALAHTDDPAQGTQDQCSQVISHLERIIKTKATLLDKENKQRRIPRGFQMLDSITLSHLIPLLIKLCGKPQTECRHQCMKLVCQVTPLLHGIGSAAIWMKNTHKEHDSFFVRRFEGGGGRGNGILTYPTLADMGGAFSLKETLLWFHYLLAALDCYTWVFGEQLLPPADLLRSKYSSVLFTSLSYFL 1137
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO44977 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU99]) HSP 1 Score: 162.155 bits (409), Expect = 3.422e-39 Identity = 149/590 (25.25%), Postives = 270/590 (45.76%), Query Frame = 2
Query: 10211 FDFNFLTAIFSS---------IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAW---LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSK-LFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVI-SKDW-LEIPGQYNNITARPFPEKH-IKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNF--DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMS------RMSKQSIETFTQ 11875
FD+ L ++ + I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ S +IL N+ +LV Q ++ + + + W L+EA+ M+ + + +Q M R L++ F + + + L EA + ++ LTQ W L + F+ + P L + Y P ++ S+D L +PG Y P K I I + + ++ SKQ P+K+ + G N + FL+K EDLRQD R+ Q+F ++N +++ D + +K + LS I+ Y VIP+S + GL+ W+ + TL ++D E++ I + P+ D ++ QK E ++ ++N D L K S E ++ R N+ + A+ Y+LG+GDRH N +++ TG I+ IDFG F +A PE IPFRLT + ++ +G+ G + T ++V+ T+ + ++M+++ F+ + +L+W M + SK +T T+
Sbjct: 1840 FDYGHLPEVYEALVEGIKTIQIDTWLQV--IPQLIARIDTPRQLVGRLIHQLLTDIGKHHPQALIYP--LTVASKSASSARHNAANQILKNMCEHSQQLVQQAVMVSEELIRVAILWHELWHEGLEEASRMYFGEGNVKGMFAVLDPLHQMMER----GPQTLKETSFNQAYGRDLMEAQEWCRRYQKSGNVKDLTQ---------------AWDLYYTVFRRISKQLPQLTSLELQ--YVSPKLLMSRDLELAVPGTYE-------PHKPVIHIRNVHSSLNVITSKQRPRKLCLAGSNGSDFMFLLKGHEDLRQDERVMQLFGLVNTLLASDPETSK--RHLS-IQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLTMAPDY----------DHLTLMQKVEVFEHALANTNGDDLAKLLWLKSPSSEVWFDRRTNYTRSLAVMSMVGYVLGLGDRHPSNLMLDRLTGRILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGIDGNYRLTCESVMRTMREHKDSVMAVLEAFVYDPLLNWRLMDNAAPKIKRSKGRSDTMTE 2380
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO36404 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SIS1]) HSP 1 Score: 131.339 bits (329), Expect = 6.490e-30 Identity = 81/305 (26.56%), Postives = 148/305 (48.52%), Query Frame = 2
Query: 10937 FPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAY----TKSWEKSDVVSTNQKFEENQNLISNFD----LLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+ ++ + F L G+ + PK I +G + LVK +DLRQD +EQ+F ++N +++ + T++ K ++TY VIP+S+ G+LEW + T+ L E+ + S + NT A+ + W D N LI D + R F+ ++ R+ + + A + Y++G+GDRH++N L++ N+ +++ ID G AF + LP PE +PFRLT +V+ + +GV G+F + + + + Q +++I+ V L + + W
Sbjct: 1347 YVDRFMPTFSLAGGVNL------PKIIACVGSDGVKRRQLVKGRDDLRQDAVMEQVFGMVNQLLANN---TETRKRKLRVRTYKVIPLSQRSGMLEWCEGTMPLGEYL--------------IGSPGH-----NTGAHQRYNPRDWSPMDCRRKMASVVRNYILIGIMDHFKPVFRHFFLEKFVDPAEWFERRLAYTRSCATSSIVGYIVGLGDRHVQNILVDCNSAELVHIDLGVAFEQGKV-LPTPETVPFRLTRDLVDGMGVTGVEGVFRRCCEKTMAVMRTSQEALVTILEVLLYDPLYSW 1622
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO48437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJW4]) HSP 1 Score: 125.561 bits (314), Expect = 3.510e-28 Identity = 119/495 (24.04%), Postives = 212/495 (42.83%), Query Frame = 2
Query: 10466 FYAALLQMGQPEYYLQAWLDEANDMFSSNSH--DSNSRQNIVNKYQDMYRKIIGNLDQLRKGQ-----------FQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFK-NLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFI-KTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQ---------------YIYKKVSSEFYTQYFPN---------TAAYTKSWEKSDVVSTNQKFEENQNLISNF--DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
+ +L+Q Q Q LDE +SN + D I K+ + R I+ L+QL+K F +S L E + S + + F ++ + + +K S + ++D SP LAK Y +PGQ + F + + I + + I+P+K PKK++ +G + Q +++L K EDL D RI Q ++ N++ ++ S + F + Y+V P+ GL++W+D V + Y + + E K S FY++ P + K W + Q EE LI+ DLL + S ++ + + + A+ Y++G+GDRHL N LI+ TG+++ ID+ F L +PE +PFR+T ++ L +GV G+F + + VL L + + T+++++ F+ + ++DW
Sbjct: 261 WLGSLIQTHQDVVRRQQQLDEEIKRVNSNVNLTDGQRAALIREKHVAIMRPIVFALEQLQKITNQQACTPHEQWFHRAYSALIEKALASLTNPANPSDARSSWDPFKQLLQTLQGR----SMKKSAYSLVMEDISPTLAKMKSTAIY------------MPGQSH------FEGEIVSISAVVNEVNILPTKTKPKKLVFVGSDGQRHTYLFKGLEDLHLDERIMQFLSICNNMFTR----ADSHRCPLFCARHYSVTPLGPRSGLIQWVDGAVPVFALYKRWQQREAATNALLKSAQGSNQPPPPPMKPSELFYSKMTPALKEKGIVDPKESGRKEWP---IAVMRQVLEE---LIAETPSDLLSRELWCSSTGALEWWHMTKTYARSTAVMSMIGYIIGLGDRHLDNMLIDFTTGEVVHIDYNVCFEKGR-GLRVPEKVPFRMTPNLEMALGVTGVEGMFRLSCEQVLKILKQGRETLLTLLEAFVYDPLVDW 722
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkdc (protein kinase, DNA-activated, catalytic subunit [Source:NCBI gene;Acc:101171206]) HSP 1 Score: 318.931 bits (816), Expect = 4.592e-86 Identity = 219/740 (29.59%), Postives = 366/740 (49.46%), Query Frame = 2
Query: 9983 YSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYV--------ADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQ----LRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMS------------RMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAE--------------TSQTKKLVSMATNSGFLARTWQGFEP 12088
YS+ + ++ + +++F D +R+ E G + DL VESTL +++L A+ +FPRLLQII + + D +T +S+P WM I W+ QM+ LD S V+ I ++A+ YP AL Y M+ A + F+ + L AL Q+ P+ + W + + + +++ + + Y++M+ + + + RK Q++FSK +++ F G+ ++ + ++ N + + NLK++SPWL S ++ D S + LE+PG+ ++P PE H KI + + +M S + PK++II GD+E+ + FLVK GEDLRQD RIEQ+F++MN ++S D T ++ + TY VIP++ ++GL+EW++NT TL +F KTM +EE K +++D V+ K ++ DLLR SF+ + E+F LR +FI +A+ +H++LGIGDRHL NF++N TG +IGIDFG+AFG AT FLP+PEL+PFRLT V ++P G+ + + L E +++ M VF+ LDW ++ + + + +++N + RKL+ +P + EEL++ + K F M+ E Q + L+ AT+ L R + G+EP
Sbjct: 3278 YSQDFVDSSSVTDTYMTLANFCDKLLREEEQSG-NLLDLPVHVVESTLKALRLSSEEARLRFPRLLQIIELYRSETLDL--MTKEMASVPCWMLICWISQMVALLDKLESVAVQHCIKQLAESYPQALVYALMISSESFHFEESAAGHQQQEFV-NLRDTLDKGGAAKNLVDALQQLTNPDMIFRDWWEGVRNELEKPTF---TKKKMRSMYEEMHSALCSHNTKGHGGFRKKFIQQKFSK----KVEELFGPGGSKLFEKRGD--PGFMKQVENLVADMRGFPKAPGNLKEYSPWL-------SGFKADSFSNE-LEVPGR-----SKPLPEYHAKITGFDERVMVMSSMRHPKRLIIRGDDERDHPFLVKGGEDLRQDQRIEQLFSIMNIVLSND---TACVQRGLQLHTYQVIPLT-TVGLIEWMENTCTLKDFVYKTMTEEE----------------------NKRAKRADAVNNFLKVLQH----VPADLLR-SFLRMCNSPEAFLSLRSHFISSHALLCVSHWILGIGDRHLSNFMVNVETGGMIGIDFGHAFGSATQFLPVPELMPFRLTQQFVNLMQPLKESGLIQSIMVHSLRAYRAEPDLLLNTMDVFIKEPCLDWKNFEVKQLRKGGTWTDSVNTKEVNWYPLQKVNFARRKLEGANPAAITSEELKLGFEKDASFAGMQAVALGSEEHNVRAKLPASGLSVEKQVECLLDHATDPNVLGRVYVGWEP 3960 HSP 2 Score: 220.32 bits (560), Expect = 2.991e-56 Identity = 303/1304 (23.24%), Postives = 553/1304 (42.41%), Query Frame = 2
Query: 329 IFIENFCDFIINLVKFAKEKLLPFCGLIKNYLMNI------VKSKKSSAKMKELSIKSLQDILTLTGNNNFEMNIGVCLSDLF----SQLQNKSS-TTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNS----KTSIISGCCEGLR----RFYKALPEKLSAKSPPTIYLLLL---KILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLV-KGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIR-SVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYD-VITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDF-SLNISDFEYSINTDSNETDLIKSY---AALSTRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLY---------KSEDVNNEKINTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLV---NSPIFIWIEEQEGSPFNQKCLAYLQMAIQLGNCYLPLGQACLDMLERWIKAFPHMGSWVKLILPSYRTLLLFSPISSDVEYDVNQKQLQEMAT-AKRGSRKLARTLRSMQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSR-YFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTW---SYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVP--PSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIP-------PSPVNAIF-WMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFL--ILDRQIDSSKDLF 4066
+F+E F D I V+ G K Y +I V +K+ AK + ++ L + L ++ +SD+F S+L KS L + EL+G + ++P+ ++S L L++++ ++ K +++GC G+ F K E L Y L ++L M+ R+A V L + H A + + +F + K H N +K ++ L+ +L+ Q+ I A+N + ++ +F +K M S T K L I+G G + C + P++ + ++Y+ + + + YL E D E LP + + IA ++I L I P Y ++ RL V I+ P+ + R ++ + + V S I V+Q +I CS PV + +D S + + I N L K L FL+ A N S L++D +K +I+++LDL K +D + ++DP + KDF F+NL + E W + L+ S+ PL+SGFYK++ +KI +FQ+ C A+F +C +++ Y DELL +CL+ ++ +S + + I+ C A L+ A++LG + PL A +D LE W P ++ + P Y +L P+ D ++ + + M++ + R R ++ + + Q S + L K++ R++++LG +G ++R L+ +S + W+ E + + +PF D+KP I L+ + IS LAL+++ Q K A E+LHSL++ ++GK+A +++ EN K P + +F + ++LA D+++V++ LF L+MQ+ +WF+ ++ +++ D V +DP + RD + + F+K S K +K +K +RIY L + S +KRLGA FNSI+ + + L+ E IF ++ VE L+ +D+ T+ Q A ++ + L + R +P P+ + + WLL + R C++L + + +P + +L + + + FE L P P V A WM+ L A + + +S+++I + K S+ A + FL + R++ +++ F
Sbjct: 77 VFLEKFLDKISQKVR----------GWEKAYATDIRDMCLAVYTKEKFAKCRTAVLELLIKLQVLQTTKASSVSADFRISDIFNKFYSELCQKSKLPDSLGKIYELLGVLSEVHPSEMVYHSDKLFKAILGELKEQMTSATREPKLFVVAGCLRGITALMVNFTKTAKEDLETSKEIFQYALKAISPQLLQMEM-TRYA-VTFGLRLIGRHAAQFSSCLMEHHRALFDTMCKLCGHINGEMKKTSYYALEAFLK----QVAILVADNI--EEHKSKLKFFMQKFCGIIKTMES-----THKELSIAIRGYGFFAGQPCKKVCPQD-VDLMYTELIQRCKQMYLTESDGEDDSFYQLPSF-LDSIASVIIHLDKI---------------PEVYTPLLERLLVVQIDSFPQYSERMQVTCSRSIIKVLVAMASKGPVLWSFISS-VHQGLIRVCSKPV----VVSEDAESSQVRTGNWKIPLSQNYLPLYKGLLDCDQLKDSGFLE--GAFESQNAALGSLSRLLYDELVKSILRIVEKLDLSVQKLHGEESQKPDDAPHILPSSDPTAHLLPNKVKDFTAFINLVDFCDLLLNKHMEY-FHSWVFPLSHELILHSIRNPLISGFYKLLSVTMKITKRIKYFQVKSACF-----------ALFSKFGKEVCVRMKQ---YKDELLASCLSFVLSLHHSIVALDIKAY--------CPA-LETALKLGLSHAPLASAAIDALEDWSLGLP-----LETMQPVYTNVL---PLLDWYLKDQDENKWEVMSSLSSRSDRGYSKVMTRLLKKSSQLSVEDA-----------PLTKVRLRVVKLLGHLGGKFNRNLVTVSSEEKMKKFVAWDS--EKRLSFAVPFTDMKPVIYLDPFLPRISELALSTSDRQTKVAACELLHSLVVYMVGKSA-QMVEGEN-KLPPMYKLHKRLFPVLLRLACDVDQVTRQLFEPLVMQLIHWFTNNKKFESQDTVAVLEAIVDGV-------------VDPMDSTL-RDFCARCIEEFVKWSI--KQTTPKQQEKSPTNMKSLFKRIYSLALHPSGFKRLGASLAFNSIYRQFEENSLV-EQFIFEVLVVFVESLALAHSDERSLTLQQCGSAIDHLKRIIKQKAPSLNQHNAKRRIPGFPADVKLCLSDMVVWLLEQCGRPQTECRHKCMELLYEFIPLLPKRSPPQWLDGMLKDRGNDLLVLCFEGGGLLSQPTLRDVTSPFSVRATLQWMDMLLAVLDCYNTFISLHIIKPQHILCKDKSSFLKATHFFLTELATRELAAAESCF 1269 HSP 3 Score: 167.933 bits (424), Expect = 1.971e-40 Identity = 211/916 (23.03%), Postives = 388/916 (42.36%), Query Frame = 2
Query: 5747 AFNCFSSVVIATQSDEKFYTNLLL----RYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKE------KPIF-NSLKYSSDKYKREPIHSVAEFLSDSSLALDVE----KLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVY---LSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLIL---KMSSINPFVESVLRLIIDWSSVPGVYDKVSKAN------INLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILH-STLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENI-QYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLF-VDLSSEKPD--ILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNM-----PQELRSYSMSHDQKFKVPTS--------INIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDND--YFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESE 8353
A+NC +V+ ++ KFY L N+ + +II + +FP E+ + ++ K+ + KE P++ +S Y +D E + S +L + K + R DS ++++ D +N H CM T + L M+ I ++ L ++P WMK H ++I+ FI KLIIN +F+PYA W+ L++ ++ + I+ V ++ + W+S+ K N N L+ +L +N + ++ R N+E+ +L+ WK + Y+ QN N GL++L +L N L A+ ++ +I+ L + L K V+ A E+ G+ LK + + + E + +IT + L F+ CL + K H I+++ S+L L LE C + ++ ++F QL + + + +++ +C + + H+ + + + A V F S P E+ L + L D S + D + + + LL G + ++ + +RNF S + LPT T+ER +L L+ ++ + R FL++ATN++LEMTS PDF + +F+ L S TF++ + P FV P+ + S SMS + K+ + P + ++W+ +S ++ + E + + +++ K L + D + + E ++ + + + K+ D F +K +Q+Q+ + + ++ K + V LYRNY G P+I+I S I PLQ LAQ + +K+LF L+ G+LKE E
Sbjct: 1870 AYNCAVAVITCCFNEPKFYQGFLFSEKPEKNQFILENIIDVERAYSFPIEIEVPLERKKKYIMIRKEVSEENGAPVYLSSQSYMADSSLSEEMSQFDFSTGVQSFSLSSQNPEGKTRTVAKRETEETQASQDS----------LVDLEMDELNQHECMATMVALIGHMQRNSITPQIQQGSLPHELPPWMKFLHGKLLKSSTPLNIRLFISKLIINTEEVFRPYAKHWLGPLLQLVVCGNNGGAGIHFMVVDIVVTALSWTSL-----ATPKGNPRDEVLANRLLEFLMKNSFHPKRAVFRHNLEIIRTLVECWK----LIYERFCGTDQNSKD---NSVGLQLLGIILANN-LPAYEASCGIEYDYIQSLTQNLSFVRYKDVYSAAAEIIGLTLKNMSTMGNEQQELLNLAASKITHLKKKDLD---DKFIICLNKVSK-HFPPFMDFINHVFSLLPKLHGLLKTSCLE---CVLSRADVIPDIFLQLKTSGFIQTLGRDEATQRVC--LDIIHKVTARLSPPELQELLGA--VAAFVSH-PSPVCRERMYDILMWILDNYDEESMQDDTSVEVLKAAKETLLQGLSEENQGL-LYVRNFWSQEKRLPTATIERMLMVLRSLY---------SRQIERC-FLSLATNLLLEMTSQSPDFKRNMFEYPL-SECTFQDYVIDSNWRFRNTVMTPMFVETQSTQGPEGVVSASMSEAMRGKLRATQTSLEFSQTQAPGRRTAYNWMTGSSVDTLADYSLSSESLSSLLVFEKKAER-----RTVTRKPVGEGFGLRRLTASTDEVDSRTKENEQRSNILRLRR----RFLKDQDKVSLSFAQKEIQQQRQKKEDKADQRLRKEAQVTLYRNYRVGDFPDIQIPYSSLITPLQALAQRDPILAKNLFSSLFAGILKEME 2729
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: mtor (mechanistic target of rapamycin kinase [Source:ZFIN;Acc:ZDB-GENE-030131-2974]) HSP 1 Score: 155.992 bits (393), Expect = 7.067e-38 Identity = 139/560 (24.82%), Postives = 261/560 (46.61%), Query Frame = 2
Query: 10247 IPSWMYIPWLDQMIPFLDCP---ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNL-----KLVHQFYAALLQMGQPE-YYLQAW---LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSK-LFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVI-SKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKD--EEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQ 11875
I +W+ + + Q+I +D P + ++ +++ I +P AL YP L VA ++ + KIL N+ LV Q ++ + + + W L+EA+ ++ + + + + ++ + L++ F + + + L EA +D Y + N + + + W L F+ + P L + Y P ++ +D L +PG Y+ +P I+I + +Q++ SKQ P+K+ I+G N + FL+K EDLRQD R+ Q+F ++N +++ D SL+ I+ Y VIP+S + GL+ W+ + TL ++D E++ I + + P+ T EK +V FE N + DL + ++ S E ++ R N+ + A+ Y+LG+GDRH N +++ +G I+ IDFG F +A PE IPFRLT + ++ +G+ G + T V+ L + ++M+++ F+ + +L+W M +K + + T+
Sbjct: 120 IDTWLQV--IPQLIARIDTPRALVGRLIHQLLTDIGRYHPQALIYP--LTVASKSTTTARHNAANKILKNMCEHCNTLVQQAMMVSEELIRVAILWHEMWHEGLEEASRLYFG----ERNVKGMFAVLEPLHAMMERGPQTLKETSFNQAYGRDLMEA-------QDWCRKYMRSGN--------VKDLTQAWDLYYHVFRRISKQLPQLTSLELQ--YVSPKLLMCRDLELAVPGTYD--PNQPI----IRIQSIAASLQVITSKQRPRKLTIMGSNGHEFMFLLKGHEDLRQDERVMQLFGLVNTLLAND---PASLRKNLSIQRYAVIPLSTNSGLIGWVPHCDTLHAL----IRDYREKKKILLNIEHRIMLRMAPDYDHLTL-MEKVEV------FEHAVNNTAGDDLAKLLWLK-SPSSEVWFDRRTNYTRSLAVMSMVGYILGLGDRHPSNLMLDRLSGKILHIDFGDCFEVAMTREKFPEKIPFRLTRMLTNAMEVTGLDGNYRITCHTVMEVLREHRDSVMAVLEAFVYDPLLNWRLMDSNTKGTKRSRTR 633
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: atr (ATR serine/threonine kinase [Source:NCBI gene;Acc:101157099]) HSP 1 Score: 122.094 bits (305), Expect = 1.278e-26 Identity = 87/302 (28.81%), Postives = 145/302 (48.01%), Query Frame = 2
Query: 10979 IQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRL-------RINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSR-MSKQSI 11860
++I+ S Q PKKI + G + + Y+ + K +DLR+D R+ + ++N + K +S + I+TY VIP+++ G++EW++NT L K K E Y+ K E P TA FEE + R + HE F R R + + A+ Y+LG+GDRH +N L + TG+ + +DF F F +PE++PFRLT +MV + P G G+F Q + L L R+Q + ++ FL + +++W + ++ +SK +
Sbjct: 1825 VEILASLQKPKKISLRGSDGRSYTMMCKPKDDLRKDCRLMEFNCLINKCLRKH---AESRRRELHIRTYAVIPLNEECGIIEWVNNTAGLRHILTKLYK-ERVYLSGK---ELRKLILPKTAP----------------FEEKLRIHKEVLCARHPPVF----HEWFLRTFPDPTSSRSAYCRSTAVMSMVGYVLGLGDRHGENILFDSFTGECVHVDFNCLFNKGETF-DVPEVVPFRLTQNMVHAMGPMGTEGLFRQACEVTL-RLMRDQREPLMVLKTFLHDPLVEWSKQTKGLSKTQV 2097
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: trrap (transformation/transcription domain associated protein [Source:NCBI gene;Acc:100304461]) HSP 1 Score: 68.9366 bits (167), Expect = 1.420e-10 Identity = 100/443 (22.57%), Postives = 191/443 (43.12%), Query Frame = 2
Query: 10532 NDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTW-KLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKH-IKIFKLEPGIQIMPSKQ-CPKKIIIIGDNEQPYSFLVKSGEDL---RQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSR 11842
+ MFSS + +S +R+ +++K+ KGQF +F +F G+ ++ N I+ +LK W K+ ++ K L F K F ++ +EIPG++ P P + IKI + P ++I+ +++ I G N + Y +LV + L R++ R+ Q+ ++N + K + TK + L F V+ +S + L+E ++++L E Y K ++ + S +Y + A T++ S V + E N++ L + T + ++ R F Q A+ A ++L + + + I ++TG + F + AT L +PFRLT ++ EFL GV G + ++ V + + I+ L ++I+ WH+ ++
Sbjct: 3347 STMFSSAASESLARRAQATAQDPVFQKM--------KGQFTTDF----------DFSVPGSM----------KLHNLIS-KLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSA----QTAEVEIPGEF----LMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK--RHL-FFTVPRVVAVSPQMRLVEDNPSSLSLVEIY-KQRCAKKGIEHDNPISRYYDRLATVQARGTQA---SHQVLRDILKEVQGNMVPRSMLKEWALHTFPNATD-YWTFRKMFTIQLALIGLAEFMLHLNRLNPEMLQIAQDTGKLNVSYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKAVLRDEIIAWHKKTQ 3744
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: trrap (transformation/transcription domain associated protein [Source:NCBI gene;Acc:100304461]) HSP 1 Score: 68.9366 bits (167), Expect = 1.491e-10 Identity = 100/447 (22.37%), Postives = 192/447 (42.95%), Query Frame = 2
Query: 10520 LDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTW-KLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKH-IKIFKLEPGIQIMPSKQ-CPKKIIIIGDNEQPYSFLVKSGEDL---RQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSR 11842
+ + MFSS + +S +R+ +++K+ KGQF +F +F G+ ++ N I+ +LK W K+ ++ K L F K F ++ +EIPG++ P P + IKI + P ++I+ +++ I G N + Y +LV + L R++ R+ Q+ ++N + K + TK + L F V+ +S + L+E ++++L E Y K ++ + S +Y + A T++ S V + E N++ L + T + ++ R F Q A+ A ++L + + + I ++TG + F + AT L +PFRLT ++ EFL GV G + ++ V + + I+ L ++I+ WH+ ++
Sbjct: 3279 VSNVSTMFSSAASESLARRAQATAQDPVFQKM--------KGQFTTDF----------DFSVPGSM----------KLHNLIS-KLKKWIKILEAKTKQLPKFFLIEEKCRFLSNFSA----QTAEVEIPGEF----LMPKPTHYYIKIARFMPRVEIVQKHNTAARRLYIRGHNGKIYPYLVMNDACLTESRREERVLQLLRLLNPCLEKRKETTK--RHL-FFTVPRVVAVSPQMRLVEDNPSSLSLVEIY-KQRCAKKGIEHDNPISRYYDRLATVQARGTQA---SHQVLRDILKEVQGNMVPRSMLKEWALHTFPNATD-YWTFRKMFTIQLALIGLAEFMLHLNRLNPEMLQIAQDTGKLNVSYFRFDINDATGDLDANRPVPFRLTPNISEFLTTIGVSGPLTASMIAVARCFAQPNFKVDGILKAVLRDEIIAWHKKTQ 3680
BLAST of DNA-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000061710.1 (SMESG000061710.1) HSP 1 Score: 6225.2 bits (16149), Expect = 0.000e+0 Identity = 3129/3161 (98.99%), Postives = 3145/3161 (99.49%), Query Frame = 2
Query: 2612 MQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILISLEPSQIYLDVRNRKKVEKWLEKIKALVKAMNANIRLSYLHEISTNLSNYSLLNEIHEISNPTGKYLNSFDIEYMFKFLKMLCLQFSDFNPLTHSIHESIFEKIILATNYEVSQISQVKFYESAALDYILVVENGLYFEKIISMLATTEMHSLFNAHREVLLKNMLLFSEKFVPYLKRENHTFXXXXXXXXXHYGIRNNLTEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENNFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYTNLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPYLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKADCFGXXXXXXXXXXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYSLSSEADTLMLQSLHFLNEICQFLQAVQKCDMPIDYISKLKGNQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL 12094
MQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNST NQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEH+NINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKND LLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSK+RIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILISLEPSQIYLDVRNRKKVEKWLEKIKALVKAMNANIRLSYLHEISTNLSNYSLLNEIHEISNPTGKYLNSFDIEYMFKFLKMLCLQFSDFNPLTHSIHESIFEKIILATNYEVSQISQVK YESAALDYILVVENGLYFEKIISMLATTEMHSLFNAHREVLLKNMLLFSEKFVPYLKRENHTFLLPLLLDLLHYGIRNNLTEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENN IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRIDITF+LIKIILIPIFCRESVHP ED+LKQTLQLLCERLDSEER KLLALFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFY NLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSSDVP WMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVL+RSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIE+NYTKELDNDYFREKAVQKQKLLLKKQKIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPYLMKLYK+LNLNEEIIGLLEIEQLSSSKNLVEKFKEALKADCFGNYNLSYDLYNSLLSE SVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMP+EISLYYI+KE+YNKAQRFCEISYDQILAGCCDYSLSSEADTLMLQSLHFLNEICQFLQAVQKCDMP+DYISKLK NQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPA SYLKSSKQKSYQGDKNSKLAWCLKYSKVHLRSAICHGSF SFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDC ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSY+QPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIM+KDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLS+FY KTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEK DVVSTNQKF+ENQ LISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIE+FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL
Sbjct: 1 MQIIEQQRSFQAMESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTNNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHENINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDTLLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKSRIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILISLEPSQIYLDVRNRKKVEKWLEKIKALVKAMNANIRLSYLHEISTNLSNYSLLNEIHEISNPTGKYLNSFDIEYMFKFLKMLCLQFSDFNPLTHSIHESIFEKIILATNYEVSQISQVKVYESAALDYILVVENGLYFEKIISMLATTEMHSLFNAHREVLLKNMLLFSEKFVPYLKRENHTFLLPLLLDLLHYGIRNNLTEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENNLIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRIDITFMLIKIILIPIFCRESVHPCEDSLKQTLQLLCERLDSEERNKLLALFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYANLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSSDVPPWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLARSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIESNYTKELDNDYFREKAVQKQKLLLKKQKIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPYLMKLYKILNLNEEIIGLLEIEQLSSSKNLVEKFKEALKADCFGNYNLSYDLYNSLLSETSVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPVEISLYYIMKENYNKAQRFCEISYDQILAGCCDYSLSSEADTLMLQSLHFLNEICQFLQAVQKCDMPLDYISKLKENQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPALSYLKSSKQKSYQGDKNSKLAWCLKYSKVHLRSAICHGSFISFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCRISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYHQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMTKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSDFYRKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKPDVVSTNQKFDENQKLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIESFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL 3161
BLAST of DNA-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000061710.1 (SMESG000061710.1) HSP 1 Score: 6200.16 bits (16084), Expect = 0.000e+0 Identity = 3117/3149 (98.98%), Postives = 3133/3149 (99.49%), Query Frame = 2
Query: 2648 MESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTTNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHKNINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDILLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKNRIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILISLEPSQIYLDVRNRKKVEKWLEKIKALVKAMNANIRLSYLHEISTNLSNYSLLNEIHEISNPTGKYLNSFDIEYMFKFLKMLCLQFSDFNPLTHSIHESIFEKIILATNYEVSQISQVKFYESAALDYILVVENGLYFEKIISMLATTEMHSLFNAHREVLLKNMLLFSEKFVPYLKRENHTFXXXXXXXXXHYGIRNNLTEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENNFIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRXXXXXXXXXXXXXXXFCRESVHPHEDTLKQTLQLLCERLDSEERIKLLALFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYTNLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSSDVPSWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLSRSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIETNYTKELDNDYFREKAVXXXXXXXXXXXIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPYLMKLYKVXXXXXXXXXXXXXXQLSSSKNLVEKFKEALKADCFGXXXXXXXXXXXXXXEASVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPIEISLYYIVKEDYNKAQRFCEISYDQILAGCCDYSLSSEADTLMLQSLHFLNEICQFLQAVQKCDMPIDYISKLKGNQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPAFXXXXXXXXXXXXGDKNSKLAWCLKYSKVHLRSAICHGSFTSFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCPISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIETFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL 12094
MESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNST NQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEH+NINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKND LLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSK+RIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILISLEPSQIYLDVRNRKKVEKWLEKIKALVKAMNANIRLSYLHEISTNLSNYSLLNEIHEISNPTGKYLNSFDIEYMFKFLKMLCLQFSDFNPLTHSIHESIFEKIILATNYEVSQISQVK YESAALDYILVVENGLYFEKIISMLATTEMHSLFNAHREVLLKNMLLFSEKFVPYLKRENHTFLLPLLLDLLHYGIRNNLTEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENN IFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRIDITF+LIKIILIPIFCRESVHP ED+LKQTLQLLCERLDSEER KLLALFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFY NLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSSDVP WMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVL+RSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIE+NYTKELDNDYFREKAVQKQKLLLKKQKIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPYLMKLYK+LNLNEEIIGLLEIEQLSSSKNLVEKFKEALKADCFGNYNLSYDLYNSLLSE SVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMP+EISLYYI+KE+YNKAQRFCEISYDQILAGCCDYSLSSEADTLMLQSLHFLNEICQFLQAVQKCDMP+DYISKLK NQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPA SYLKSSKQKSYQGDKNSKLAWCLKYSKVHLRSAICHGSF SFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDC ISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSY+QPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIM+KDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLS+FY KTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEK DVVSTNQKF+ENQ LISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIE+FTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL
Sbjct: 1 MESEINDNNSLNKLEKLQNRLIRILGKMGINYSRYLIRDNSRYFSDNINWNKSYEPIILYELPFKDIKPDIRLEWLITPISSLALNSTNNQVKSLASEVLHSLIIILLGKTATTILKIENIKFIPTWSYIFTISIKLATDMNKVSKTLFSDLLMQIAYWFSYPDNSDNPAVECFIDSCFDTVIYIPTEDCSHKISIDPNSGNVQRDLAGQLLFYFLKSSFEHENINSDILKKVNRKIKRFLQRIYFLCQNFSPYKRLGAVFIFNSIFPILKNDTLLMENEIFAMMYYLVECQRLSENDKHLGTINQLKLAFKNIGNAARSLKSKLMDVSKSRIVPPSWTAATIEFAIRWLLNYYLSDKRRLRQVCIDLSEQLSFCYDETNPNSFFKALLTAKPLEYITKKFESTELFKIPPSPVNAIFWMNTLEASVQSFCWLLSMNLIDAYNYFTKGVSNLFTAVNNFLILDRQIDSSKDLFQLSVNFISFFQMIFSFVDKPDFVYDFVDANNLMRYFILISLEPSQIYLDVRNRKKVEKWLEKIKALVKAMNANIRLSYLHEISTNLSNYSLLNEIHEISNPTGKYLNSFDIEYMFKFLKMLCLQFSDFNPLTHSIHESIFEKIILATNYEVSQISQVKVYESAALDYILVVENGLYFEKIISMLATTEMHSLFNAHREVLLKNMLLFSEKFVPYLKRENHTFLLPLLLDLLHYGIRNNLTEKKSIVQVLGDNWFQIDPFSYYDPEVNQNNLNLTIDLLLEMMLIDSNICENNLIFDFFCNLLSSTNLLITFKNKIIPAMTHFFKYATQNEGSSFKIIENIKTFFDRNFLALSKDLQSDLSLEECYLNSISAVFHCLQIPCRIDITFMLIKIILIPIFCRESVHPCEDSLKQTLQLLCERLDSEERNKLLALFEDELKLIKAYENIIWFLNKFYFVIILKCDIQNLTNFFGSRIDQLLENIKINNFENPNERELQNVIVNLKIISTIYTSLGPFCNQDKVGLREKKLIGELSKICSLILYCKSDDSTNKLIYQMIYNVRSWAFNCFSSVVIATQSDEKFYANLLLRYNKPLFRHIIYKDYVINFPSELLIFKMKQTKFYTLNKEKPIFNSLKYSSDKYKREPIHSVAEFLSDSSLALDVEKLENILSRNVNSNLMDSDSFLQHDGRCLMIINIPYDIVNDHPCMDTFICLHHQMKNVGIISEVYLSSDVPPWMKVTHDTFFAQDCYIDIKYFIVKLIINCHHIFKPYASFWMVGLIEFLILKMSSINPFVESVLRLIIDWSSVPGVYDKVSKANINLLINWLAENCYSDNPSIVRTNIELFFSLLNLWKEKVDIPYKPIFDNLQNVSKGLRNCCGLKMLAAVLTNGYLFMAGANNDTKFGFIKQLVKILHSTLKTVFGPAFELCGILLKQILKDSDSKSEWVLEIEKEITLTFEAVLARSKSDFVTCLALIGKNHSDIICRQISNLMSILKSLTDNDYCKALELLGCGMRDSNEWLELFNQLVEWNIFENIQYKSSSVICAIIQLFHQAITNIPEWKNDSQINANVVKCFESCLPCSTQDEKKVRSLFFQLFVDLSSEKPDILFVNCFQSALLMGFIDPDKDISQSIRNFCSSSQCLPTETLERSCKILEILFPESNSIISVNKFLNRSKFLAIATNIVLEMTSHCPDFVKPIFQIHLDSTATFENLTASKMNSQTTRSLLPNFVNMPQELRSYSMSHDQKFKVPTSINIPKQAKNFDWIQLASTLQFPSQEINENNYKDEYSMEWSSSQIPGVDMSLSIKSQKSFLNLSTSVMHIENEDKASNQQENQTEFQTINKTIESNYTKELDNDYFREKAVQKQKLLLKKQKIEKNIKNSAVYLYRNYHTGKLPNIKIQNCSFIAPLQMLAQLNEEFSKDLFCHLYNGLLKESEFFPHSGVFEGFCQNLSQQFDNILKTCDMADKNLISSCLQIAIVNISKINLNPSFVYNASTLSGNEVLATVLLEKYLIGHLKSSKFDSNEIPPAKKLKLSETNTGSSLIPYLMKLYKILNLNEEIIGLLEIEQLSSSKNLVEKFKEALKADCFGNYNLSYDLYNSLLSETSVDENNEFEYELLSVSQNGLIDSLKKLCKWTELTKFLNCMIGETLSSQNFEIAKSVVNSKLRTLVFEKNVDEGHTISELDELVKRFQISIPNYELLMPVEISLYYIMKENYNKAQRFCEISYDQILAGCCDYSLSSEADTLMLQSLHFLNEICQFLQAVQKCDMPLDYISKLKENQGDLEKESLEFWENLLFYRTVYLKKGMMKFPFLAEAITTEISDLQMQFIDACIIHNRMSPALSYLKSSKQKSYQGDKNSKLAWCLKYSKVHLRSAICHGSFISFNEAPEILIGLTNSVKLLLKFPNTDINYSLEYLLSLGDCYWTLGNVLSLHWQSEPENKIINSILELIDHTGDYTKDSLICGLLNKSFYCFNKIISMYSESDGNKKELSAALVVVSDFYDAQIRQFENDGPSRPDLIRSYVESTLYSMKLEQFSAKNKFPRLLQIINQHALDIFDFNFLTAIFSSIPSWMYIPWLDQMIPFLDCRISHIVESIISRIADDYPHALFYPFMLYVADVTSKSNFICKIGKILSNLKLVHQFYAALLQMGQPEYYLQAWLDEANDMFSSNSHDSNSRQNIVNKYQDMYRKIIGNLDQLRKGQFQEEFSKLFEADIKDNFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYHQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMTKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSDFYRKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKPDVVSTNQKFDENQKLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDWHRMSRMSKQSIESFTQKRINISHRKLKREDPLLLLYEELQIKYGKSNWFKCMKNFQSEDAETSQTKKLVSMATNSGFLARTWQGFEPVL 3149
BLAST of DNA-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000061709.1 (SMESG000061709.1) HSP 1 Score: 1481.08 bits (3833), Expect = 0.000e+0 Identity = 729/737 (98.91%), Postives = 732/737 (99.32%), Query Frame = 2
Query: 116 MTDAGLINLKYALKKSLECESPDTVNIINRIHSYCLCEFNFPRLSSILKELFENEPKLLDIYSNNETKVYQIFIENFCDFIINLVKFAKEKLLPFCGLIKNYLMNIVKSKKSSAKMKELSIKSLQDILTLTGNNNFEMNIGVCLSDLFSQLQNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNSKTSIISGCCEGLRRFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNVALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHEREAFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDDKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSNDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEKINTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKTLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQE 2326
MTDAGLINLKYALKKSLE ESPDTVNIINRIHSYCLCEFNFPRLSSILKELFENEPKLLDIYSNNETKVYQIFIENFCDFIINLVKFAKEKLLPFCGLIKNYLMNI+KSKKSSAKMKELSIKSLQDILTLTGNNNFEMNIGVCL DLFSQLQNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNSKTSIISGCCEGLRRFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNN ALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHERE FEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPD+KMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQS+DDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEKINTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIK LICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQE
Sbjct: 1 MTDAGLINLKYALKKSLEGESPDTVNIINRIHSYCLCEFNFPRLSSILKELFENEPKLLDIYSNNETKVYQIFIENFCDFIINLVKFAKEKLLPFCGLIKNYLMNILKSKKSSAKMKELSIKSLQDILTLTGNNNFEMNIGVCLGDLFSQLQNKSSTTVLSALIELIGKICLLYPNSFTHYSSDYEGIALNLLQKEINNSKTSIISGCCEGLRRFYKALPEKLSAKSPPTIYLLLLKILHMDSGYRFAAVKSCLHFLTDHWANLKYDIFGDTQQIFPCILKHINHNNAALKFSAQTCLDKYLEYIGEQIQIKFANNTLSSHERETFEYLFGQFNTNLKKMRSVQNLPTDKFLDTDIKGLGQLVKGCSVLLPKETLGILYSIIGEYVWKEYLLEKDQEQIRSVLPRYKIYPIADILISLTMIVDALCSSKQFEILQYPRKYDVITRLTNVFIEFSPRLPDEKMYLYRRIFNAIVDNLKAHETVRISIIDKIVYQAIILSCSFPVPPDFSIIQDFSLNISDFEYSINTDSNETDLIKSYAALSTRDFLQFWNAILQSDDDKDECSVLIFDSFMKCAYKIIDQLDLLYKSEDVNNEKINTDPMIGQSASTPKDFIIFVNLCQLFQFVTKFGNENKIKKWASFCINYLVTRSLELPLVSGFYKMICSIIKILDSFGFFQINLECTKVADNRGLCKDAIFYDIKRLICSMLEKICNYNDELLITCLTLLVNSPIFIWIEEQE 737
BLAST of DNA-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000025384.1 (SMESG000025384.1) HSP 1 Score: 162.155 bits (409), Expect = 7.598e-39 Identity = 110/379 (29.02%), Postives = 194/379 (51.19%), Query Frame = 2
Query: 10694 NFREDGTSIYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDW-LEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGKTMKDEEQYIYKKVSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQNLISNFDLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
N++ D T + + N + + +I+N + T +L V+ SP L YN DW L IPG Y+ RP +KI ++ + +M SKQ P+K+ IIGD+ Y FL+K ED+RQD R Q F ++N +M + Q ++ LS I+ +VIP+S + GL+ W+ N+ TL+ ++D Y++ + + +EK +++ + FE DL ++ S E+++ R NFI+ A+ Y+LG+GDRH N ++ ++G +I IDFG F +AT+ PE +PFRLT ++ ++ +G+ G+F T ++ + + + ++++++ FL + +L W
Sbjct: 2317 NYKTDLTQAWEIYSNLYRKWSKQISN-VSTLELSVA--------SPRLHDYN-------------DWILAIPGSYD--PNRPI----VKINSIKNCLNLMTSKQHPRKLTIIGDDGHNYMFLLKGHEDIRQDERAMQFFGLINTLMVSNRQTSRI--NLS-IQRMSVIPLSTNTGLIGWVPNSDTLN----AVIRD-----YREKTQVLLNREHKEMLKIAPDFEKLNIIQKTEVFESGIRESDGKDLAHILWLK-SHNSEAWFERRTNFIRSLAVMSMVGYILGLGDRHPSNIMLCRDSGKVIHIDFGDCFEVATMREKYPEKVPFRLTRMLIGAMEVTGIEGLFRHTSIQIVNLMRKNRESLLAVLEAFLHDPLLQW 2654
BLAST of DNA-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000009788.1 (SMESG000009788.1) HSP 1 Score: 129.413 bits (324), Expect = 5.672e-29 Identity = 116/429 (27.04%), Postives = 187/429 (43.59%), Query Frame = 2
Query: 10649 FQEEFSKLFEADIK--DNFREDGTS---IYTLTQNQFSEIRNRINNQLKTWKLKVSEFKNLKDFSPWLAKYNFRDSYYQPDVISKDWLEIPGQYNNITARPFPEKHIKIFKLEPGIQIMPSKQCPKKIIIIGDNEQPYSFLVKSGEDLRQDYRIEQMFTVMNDIMSKDYQLTKSLKALSFIKTYNVIPISKSLGLLEWIDNTVTLSEFYGK-TMKDEEQYIYKK----------------VSSEFYTQYFPNTAAYTKSWEKSDVVSTNQKFEENQN-----LISNF---------DLLRKSFMTISKCHESFYRLRINFIQQYAMTVAAHYLLGIGDRHLKNFLINENTGDIIGIDFGYAFGIATIFLPIPELIPFRLTSSMVEFLKPSGVGGIFSQTLDNVLGTLGREQLTIMSIMHVFLTNQILDW 11827
F EE + E +IK +N RE + I TL + +E + I +LK + + K L D SP LAK N + +PG N + ++ I I+P+K PKK + N + YS+L K EDLR D R+ Q+ + N + SK + + I TY V P+ GL++ ++ +L Y + M+++ + + K + SE P + K K + + + + LI F DLL K S ++YR INF + A+ + LG+GDRHL N L+N + G +I ID+ F + L +PE +PFRLT + P V G+F + +NV + + Q +I+++M +F+ + I+DW
Sbjct: 1920 FAEEITSTIE-EIKSPNNIREFNDAWKKIKTLQELILTESNDNIKVKLKRGRHQFLSLK-LDDVSPGLAKIN------------SSLIPLPGMNNK-----------SLLSIDKHISILPTKTKPKKFRFLSTNGKYYSYLYKGLEDLRLDERVMQILGIANTMFSK---INEHESNKYHITTYPVTPLGTRAGLIQMVEEATSLFSLYKRHQMRNKNTFDHLKSKACHSNNGDIVNESTIISEEGHPIRPTDIYWQKLRPKLEAAKIDIGIDSREKWPMNILIEVFNELNRDTSPDLLSKELWCCSINSNNWYRSSINFTRSCAVMCIMGHCLGLGDRHLDNLLVNFSNGQMIHIDYNVCFD-KGVSLKVPEKVPFRLTDIITNVFGPMAVNGLFRISCENVYEIIQQSQDSILTLMDMFIFDPIVDW 2319 The following BLAST results are available for this feature:
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of DNA-dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30035077 ID=SMED30035077|Name=DNA-dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=12541bpback to top protein sequence of SMED30035077-orf-1 >SMED30035077-orf-1 ID=SMED30035077-orf-1|Name=SMED30035077-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=3994bp MTDAGLINLKYALKKSLECESPDTVNIINRIHSYCLCEFNFPRLSSILKEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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