Aquaporin

Overview
NameAquaporin
Smed IDSMED30035058
Length (bp)1212
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Aquaporin (SMED30035058) t-SNE clustered cells

Violin plots show distribution of expression levels for Aquaporin (SMED30035058) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Aquaporin (SMED30035058) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Aquaporin (SMED30035058) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035058

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 17

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
pigment cellSMED30035058h1SMcG0022090 SmedASXL_002978SmedAsxl_ww_GCZZ01PMID:29158443
He et al., 2017		whole organism asexual adult RNA-sequencing evidence
nervous systemSMED30035058h1SMcG0022090 dd_Smed_v4_1224_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
gutSMED30035058h1SMcG0022090 dd_Smed_v4_1224_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035058h1SMcG0022090 dd_Smed_v4_1224_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30035058h1SMcG0022090 dd_Smed_v4_1224_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035058h1SMcG0022090 dd_Smed_v4_1224_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30035058h1SMcG0022090 dd_Smed_v4_1224_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30035058h1SMcG0022090 dd_Smed_v4_1103_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035058h1SMcG0022090 dd_Smed_v4_1103_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035058h1SMcG0022090 dd_Smed_v4_1103_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30035058h1SMcG0022090 dd_Smed_v4_1103_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035058h1SMcG0022090 Contig50017uc_Smed_v2PMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
Smed sexual biotypeSMED30035058h1SMcG0022090 Contig50017newmark_estsPMID:29674431
Fincher et al., 2018		FACS sorted cell population adult hermaphrodite single-cell RNA-sequencing evidence
parenchymaSMED30035058h1SMcG0022090 dd_1103dd_Smed_v4PMID:29674431
Fincher et al., 2018		whole organism asexual adult fluorescence in situ hybridization evidence
parenchymal cellSMED30035058h1SMcG0022090 dd_Smed_v6_1103_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30035058h1SMcG0022090 dd_Smed_v6_1103_0dd_Smed_v6PMID:29674432
Plass et al., 2018		whole organism asexual adult colorimetric in situ hybridization evidence
glial cellSMED30035058h1SMcG0022090 dd_Smed_v6_1224_0dd_Smed_v6PMID:29674432
Plass et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Aquaporin vs. Ensembl Human
Match: AQP1 (aquaporin 1 (Colton blood group) [Source:HGNC Symbol;Acc:HGNC:633])

HSP 1 Score: 108.227 bits (269), Expect = 2.228e-26
Identity = 87/286 (30.42%), Postives = 136/286 (47.55%), Query Frame = 1 
Query:   70 LASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPV-----------KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFS------HDFDSHDTNS 876
            +AS FK  K L  W++++AE L T L  FI  GS      PV           KV L FGL+   +   +G ISG H+NPAV+ GLL++ QIS+ R ++YI  Q +GA      +S +T          S L+ N+L + + AD      ++  + L ++I+  L +   ++ T  R      R     G APL IG+S+ +G    ++ +G  +NPA S    + T          VGP +GG LA ++   +     S L  +  +++      +D D+ D NS
Sbjct:    1 MASEFK--KKL-FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGIT----------SSLTGNSLGRNDLAD-----GVNSGQGLGIEIIGTLQLVLCVLATTDR------RRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINS 262
[Close]
BLAST of Aquaporin vs. Ensembl Human
Match: AQP1 (aquaporin 1 (Colton blood group) [Source:HGNC Symbol;Acc:HGNC:633])

HSP 1 Score: 108.227 bits (269), Expect = 2.228e-26
Identity = 87/286 (30.42%), Postives = 136/286 (47.55%), Query Frame = 1 
Query:   70 LASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPV-----------KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFS------HDFDSHDTNS 876
            +AS FK  K L  W++++AE L T L  FI  GS      PV           KV L FGL+   +   +G ISG H+NPAV+ GLL++ QIS+ R ++YI  Q +GA      +S +T          S L+ N+L + + AD      ++  + L ++I+  L +   ++ T  R      R     G APL IG+S+ +G    ++ +G  +NPA S    + T          VGP +GG LA ++   +     S L  +  +++      +D D+ D NS
Sbjct:    1 MASEFK--KKL-FWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGIT----------SSLTGNSLGRNDLAD-----GVNSGQGLGIEIIGTLQLVLCVLATTDR------RRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINS 262
[Close]
BLAST of Aquaporin vs. Ensembl Human
Match: AQP4 (aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637])

HSP 1 Score: 107.071 bits (266), Expect = 1.070e-25
Identity = 80/291 (27.49%), Postives = 135/291 (46.39%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS--------NMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L   +   +  GS  +         ++ V + L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     +++   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +     +    + VGP++G  LA  L + VF  ++     + F  +    +  T     +  +N + ++ D +
Sbjct:    3 AFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFK--RRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDL 270
[Close]
BLAST of Aquaporin vs. Ensembl Human
Match: AQP4 (aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637])

HSP 1 Score: 107.071 bits (266), Expect = 1.070e-25
Identity = 80/291 (27.49%), Postives = 135/291 (46.39%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS--------NMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L   +   +  GS  +         ++ V + L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     +++   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +     +    + VGP++G  LA  L + VF  ++     + F  +    +  T     +  +N + ++ D +
Sbjct:    3 AFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFK--RRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDL 270
[Close]
BLAST of Aquaporin vs. Ensembl Human
Match: AQP4 (aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637])

HSP 1 Score: 107.071 bits (266), Expect = 1.919e-25
Identity = 80/291 (27.49%), Postives = 135/291 (46.39%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS--------NMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L   +   +  GS  +         ++ V + L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     +++   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +     +    + VGP++G  LA  L + VF  ++     + F  +    +  T     +  +N + ++ D +
Sbjct:   25 AFKGVWTQAFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVEFK--RRFKEAFSKAAQQTKGSYMEVEDNRSQVETDDL 292
[Close]
BLAST of Aquaporin vs. Ensembl Celegans
Match: aqp-6 (AQuaPorin or aquaglyceroporin related [Source:UniProtKB/TrEMBL;Acc:D5MCS1])

HSP 1 Score: 91.2781 bits (225), Expect = 6.100e-21
Identity = 74/265 (27.92%), Postives = 119/265 (44.91%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIG---FGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSL----------------AKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSIL 822
            +D K   ++    AE +   L  +IG      VF +   +      G+A  V+    G +SG HINPAV+FG+ +  +IS I  + Y+  Q+LG+ FG L + I    K+ N     ++S+          Y   E +            E+V T++LV TV+   V+  +N     LAPL IG S+ + +     ISG SMNPA S                 A++M          + +GP++G F+AA + ++ F  +  +L
Sbjct:    3 EDEKDYTIYSKCAAEFIAVLLFVYIGSMQAAGVFLHDGVLHAAFAHGVAIFVLAATFGGVSGAHINPAVTFGIALVGRISPIHAVCYVVSQLLGSVFGALLVRISLPYKMYN-----VISAG--ATLCGKGYNWQEGLT----------AEIVTTYILVQTVLLCAVDTDKNR----LAPLAIGFSLIIEILAAGAISGASMNPARSFGPNIMGQVFLKPEHLDAQYMYWNYHW---IYYIGPIIGAFIAAGVYRMFFARDYRVL 243
[Close]
BLAST of Aquaporin vs. Ensembl Celegans
Match: aqp-6 (AQuaPorin or aquaglyceroporin related [Source:UniProtKB/TrEMBL;Acc:D5MCS1])

HSP 1 Score: 91.6633 bits (226), Expect = 1.094e-20
Identity = 74/265 (27.92%), Postives = 119/265 (44.91%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIG---FGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSL----------------AKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSIL 822
            +D K   ++    AE +   L  +IG      VF +   +      G+A  V+    G +SG HINPAV+FG+ +  +IS I  + Y+  Q+LG+ FG L + I    K+ N     ++S+          Y   E +            E+V T++LV TV+   V+  +N     LAPL IG S+ + +     ISG SMNPA S                 A++M          + +GP++G F+AA + ++ F  +  +L
Sbjct:   48 EDEKDYTIYSKCAAEFIAVLLFVYIGSMQAAGVFLHDGVLHAAFAHGVAIFVLAATFGGVSGAHINPAVTFGIALVGRISPIHAVCYVVSQLLGSVFGALLVRISLPYKMYN-----VISAG--ATLCGKGYNWQEGLT----------AEIVTTYILVQTVLLCAVDTDKNR----LAPLAIGFSLIIEILAAGAISGASMNPARSFGPNIMGQVFLKPEHLDAQYMYWNYH---WIYYIGPIIGAFIAAGVYRMFFARDYRVL 288
[Close]
BLAST of Aquaporin vs. Ensembl Celegans
Match: aqp-6 (AQuaPorin or aquaglyceroporin related [Source:UniProtKB/TrEMBL;Acc:D5MCS1])

HSP 1 Score: 91.2781 bits (225), Expect = 1.619e-20
Identity = 74/265 (27.92%), Postives = 119/265 (44.91%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIG---FGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSL----------------AKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSIL 822
            +D K   ++    AE +   L  +IG      VF +   +      G+A  V+    G +SG HINPAV+FG+ +  +IS I  + Y+  Q+LG+ FG L + I    K+ N     ++S+          Y   E +            E+V T++LV TV+   V+  +N     LAPL IG S+ + +     ISG SMNPA S                 A++M          + +GP++G F+AA + ++ F  +  +L
Sbjct:   50 EDEKDYTIYSKCAAEFIAVLLFVYIGSMQAAGVFLHDGVLHAAFAHGVAIFVLAATFGGVSGAHINPAVTFGIALVGRISPIHAVCYVVSQLLGSVFGALLVRISLPYKMYN-----VISAG--ATLCGKGYNWQEGLT----------AEIVTTYILVQTVLLCAVDTDKN----RLAPLAIGFSLIIEILAAGAISGASMNPARSFGPNIMGQVFLKPEHLDAQYMYWNYHW---IYYIGPIIGAFIAAGVYRMFFARDYRVL 290
[Close]
BLAST of Aquaporin vs. Ensembl Celegans
Match: aqp-4 (AQuaPorin or aquaglyceroporin related [Source:UniProtKB/TrEMBL;Acc:G5EEK0])

HSP 1 Score: 73.1738 bits (178), Expect = 1.924e-14
Identity = 67/255 (26.27%), Postives = 110/255 (43.14%), Query Frame = 1 
Query:   67 RLASSFKDLKSLNLWQSIIAELLGTFLLAFIGF--GSVFSNMNPV-KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAK------FMCTKQSKGLISHIV---GPLLGGFLAAILQQL 795
            R +S     K  +L    +AE LG     ++G    S+F   + +       G    +++   G ISGGH NPAVS+ +  A ++ +     Y+  Q+LG   G    +             ++LS   LT   +    ++      + L    + E V+TF LV T++    +         LAPL IG+++++ +    +I+G SMNPA SL        F   K S    +H +   GPLLG  +A  + +L
Sbjct:   30 RKSSYTSRKKEYSLLTKCVAEFLGDLTFVYVGTMQASLFQYADGILHAAFAHGFTIFILVTAFGHISGGHFNPAVSWAIAGAGKMPIFHLPFYVVSQLLGGICGAFLTA-------------AVLSQEQLTSCEAGATLLSPGSQWWQGL----IAETVVTFFLVHTILITAADTDT----VTLAPLAIGLTLSIDILSTGSITGASMNPARSLGPSIIGSIFATQKTSFYWNNHYIYWAGPLLGSTIALCIYKL 263
[Close]
BLAST of Aquaporin vs. Ensembl Celegans
Match: aqp-2 (AQuaPorin or aquaglyceroporin related [Source:UniProtKB/TrEMBL;Acc:Q17571])

HSP 1 Score: 72.0182 bits (175), Expect = 5.840e-14
Identity = 73/253 (28.85%), Postives = 112/253 (44.27%), Query Frame = 1 
Query:   67 RLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNP-------VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENI-DKIKDLHLKILC----ELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGIS-ITVGVYCGMNISGGSMNPAVSLAKFMCTKQ-------SKGLISHIVGPLLG 765
            +L + F   K   L ++++AE  GT+LL  IG   V   + P       + V +GFG+A V  +     +SGGHINPAVSF  L   QI++++FI Y   Q  GA FG   +  +    +      ++      T     D   T  I       HL ++     + V T V VF +  +  +++  PT   L P+++G   + +G   G N  G  +NPA   A  + T         +K     IVGP +G
Sbjct:    5 KLRAKFHIRK--ELLRAVLAEFTGTYLLCLIGLSVVAQKVLPRPEVNEFIGVNVGFGIAIVFGVAVSAKLSGGHINPAVSFAFLSVGQITIVQFIAYFVAQFFGAFFGAATVYAVYNDAI------NVFDGGVRTVGGPKD---TAGIFASYPAPHLGLVNGFVDQFVATAVFVFLIAHIVDKRNSYPTW--LQPILVGTGFVAIGAAFGYN-CGYPVNPARDFAPRLFTSIFYGGAVFTKWFWVPIVGPFVG 243
[Close]
BLAST of Aquaporin vs. Ensembl Fly
Match: Drip (gene:FBgn0015872 transcript:FBtr0331389)

HSP 1 Score: 115.546 bits (288), Expect = 1.225e-29
Identity = 81/250 (32.40%), Postives = 123/250 (49.20%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLF 843
            ++  +W+ ++ EL+GTF L F+G GS  S   P ++   FGL    I   +G +SG HINPAV+ G LI  +IS+++   YI VQ +GA  G   I +   G          ++  +L            + D   +    +L E +ITF+LVF V++   +  R    KG APL +G++I  G  C + +SG SMNPA S    +          + VGP+ GG LA I+ +L+F          S+ F
Sbjct:   12 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP-QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDG----------VAGGDLG---------VSSFDPSLNCAQAVLIEALITFILVF-VVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYWVGPIAGGLLAGIIYRLIFKVRKGDDETDSYDF 239
[Close]
BLAST of Aquaporin vs. Ensembl Fly
Match: Drip (gene:FBgn0015872 transcript:FBtr0088141)

HSP 1 Score: 115.546 bits (288), Expect = 1.441e-29
Identity = 81/250 (32.40%), Postives = 123/250 (49.20%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLF 843
            ++  +W+ ++ EL+GTF L F+G GS  S   P ++   FGL    I   +G +SG HINPAV+ G LI  +IS+++   YI VQ +GA  G   I +   G          ++  +L            + D   +    +L E +ITF+LVF V++   +  R    KG APL +G++I  G  C + +SG SMNPA S    +          + VGP+ GG LA I+ +L+F          S+ F
Sbjct:   18 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP-QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDG----------VAGGDLG---------VSSFDPSLNCAQAVLIEALITFILVF-VVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYWVGPIAGGLLAGIIYRLIFKVRKGDDETDSYDF 245
[Close]
BLAST of Aquaporin vs. Ensembl Fly
Match: Drip (gene:FBgn0015872 transcript:FBtr0088142)

HSP 1 Score: 115.546 bits (288), Expect = 1.441e-29
Identity = 81/250 (32.40%), Postives = 123/250 (49.20%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLF 843
            ++  +W+ ++ EL+GTF L F+G GS  S   P ++   FGL    I   +G +SG HINPAV+ G LI  +IS+++   YI VQ +GA  G   I +   G          ++  +L            + D   +    +L E +ITF+LVF V++   +  R    KG APL +G++I  G  C + +SG SMNPA S    +          + VGP+ GG LA I+ +L+F          S+ F
Sbjct:   18 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP-QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDG----------VAGGDLG---------VSSFDPSLNCAQAVLIEALITFILVF-VVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYWVGPIAGGLLAGIIYRLIFKVRKGDDETDSYDF 245
[Close]
BLAST of Aquaporin vs. Ensembl Fly
Match: Drip (gene:FBgn0015872 transcript:FBtr0331387)

HSP 1 Score: 115.161 bits (287), Expect = 1.687e-29
Identity = 81/250 (32.40%), Postives = 123/250 (49.20%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLF 843
            ++  +W+ ++ EL+GTF L F+G GS  S   P ++   FGL    I   +G +SG HINPAV+ G LI  +IS+++   YI VQ +GA  G   I +   G          ++  +L            + D   +    +L E +ITF+LVF V++   +  R    KG APL +G++I  G  C + +SG SMNPA S    +          + VGP+ GG LA I+ +L+F          S+ F
Sbjct:   16 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP-QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDG----------VAGGDLG---------VSSFDPSLNCAQAVLIEALITFILVF-VVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYWVGPIAGGLLAGIIYRLIFKVRKGDDETDSYDF 243
[Close]
BLAST of Aquaporin vs. Ensembl Fly
Match: Drip (gene:FBgn0015872 transcript:FBtr0331388)

HSP 1 Score: 115.161 bits (287), Expect = 1.699e-29
Identity = 81/250 (32.40%), Postives = 123/250 (49.20%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLF 843
            ++  +W+ ++ EL+GTF L F+G GS  S   P ++   FGL    I   +G +SG HINPAV+ G LI  +IS+++   YI VQ +GA  G   I +   G          ++  +L            + D   +    +L E +ITF+LVF V++   +  R    KG APL +G++I  G  C + +SG SMNPA S    +          + VGP+ GG LA I+ +L+F          S+ F
Sbjct:   15 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP-QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDG----------VAGGDLG---------VSSFDPSLNCAQAVLIEALITFILVF-VVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYWVGPIAGGLLAGIIYRLIFKVRKGDDETDSYDF 242
[Close]
BLAST of Aquaporin vs. Ensembl Zebrafish
Match: aqp1a.1 (aquaporin 1a (Colton blood group), tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7764])

HSP 1 Score: 108.612 bits (270), Expect = 8.575e-27
Identity = 76/243 (31.28%), Postives = 118/243 (48.56%), Query Frame = 1 
Query:   82 FKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMN------PVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKV--LNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAIL 786
              +LKS   W++++AELLG  L  F+   +   N N       +KV L FGL+   +   +G ISG H+NPAV+ GLL + QISL+R ++YI  Q++GAT     +  ++KG    LN  H  I +                           +  EL+ TF LV  V+    ++ R+ +  G APL IG+S+ +G    ++ +G  +NPA +    M          + VGP+ GG  AA++
Sbjct:    1 MNELKSKAFWRAVLAELLGMTLFIFLSITAAVGNTNTQNPDQEIKVALAFGLSIATLAQSLGHISGAHLNPAVTLGLLASCQISLLRAVMYILAQMIGATVASAIVLGVSKGDALGLNQIHTDISAGQG------------------------VGIELLATFQLVLCVLATTDKRRRDVS--GSAPLAIGLSVCLGHLTAISFTGCGINPARTFGPAMIRLDFANHWVYWVGPMCGGVAAALI 217
[Close]
BLAST of Aquaporin vs. Ensembl Zebrafish
Match: aqp4 (aquaporin 4 [Source:ZFIN;Acc:ZDB-GENE-040724-152])

HSP 1 Score: 109.383 bits (272), Expect = 1.613e-26
Identity = 80/254 (31.50%), Postives = 124/254 (48.82%), Query Frame = 1 
Query:   76 SSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS----NMNP-----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSN 810
            ++FK + +   W+++  E L   +   +  GS  +      NP     V + L FGL+   ++ C G ISG HINPAV+  ++  R++SL + + Y+  Q LGA  G   +  +T          S+     +T  N          ++I   H  I+ EL+ITF LVFTV   C  K RN   KG A L IG+S+ +G    +  +G SMNPA S    +   + +    + VGPL+GG LAA + + +F  +
Sbjct:   25 AAFKGVWTQEFWRAVSGEFLAMIIFVLLSLGSTINWGAKQENPPPADLVLISLCFGLSIATLVQCFGHISGAHINPAVTVAMVATRKLSLAKGVFYLLAQCLGAVVGAAILYGVTPA--------SVRGGMGVTSVN----------EEISAGH-AIVIELIITFELVFTVFATCDPK-RNDL-KGSAALAIGLSVCIGHLFAIPYTGASMNPARSFGPAVIMVKWQDHWVYWVGPLIGGILAAAVYEYLFCPD 257
[Close]
BLAST of Aquaporin vs. Ensembl Zebrafish
Match: aqp4 (aquaporin 4 [Source:ZFIN;Acc:ZDB-GENE-040724-152])

HSP 1 Score: 108.997 bits (271), Expect = 2.258e-26
Identity = 80/254 (31.50%), Postives = 124/254 (48.82%), Query Frame = 1 
Query:   76 SSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS----NMNP-----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSN 810
            ++FK + +   W+++  E L   +   +  GS  +      NP     V + L FGL+   ++ C G ISG HINPAV+  ++  R++SL + + Y+  Q LGA  G   +  +T          S+     +T  N          ++I   H  I+ EL+ITF LVFTV   C  K RN   KG A L IG+S+ +G    +  +G SMNPA S    +   + +    + VGPL+GG LAA + + +F  +
Sbjct:   33 AAFKGVWTQEFWRAVSGEFLAMIIFVLLSLGSTINWGAKQENPPPADLVLISLCFGLSIATLVQCFGHISGAHINPAVTVAMVATRKLSLAKGVFYLLAQCLGAVVGAAILYGVTPA--------SVRGGMGVTSVN----------EEISAGH-AIVIELIITFELVFTVFATCDPK-RNDL-KGSAALAIGLSVCIGHLFAIPYTGASMNPARSFGPAVIMVKWQDHWVYWVGPLIGGILAAAVYEYLFCPD 265
[Close]
BLAST of Aquaporin vs. Ensembl Zebrafish
Match: CR450824.2 (aquaporin-4-like [Source:NCBI gene;Acc:101885864])

HSP 1 Score: 107.457 bits (267), Expect = 3.446e-26
Identity = 75/271 (27.68%), Postives = 131/271 (48.34%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMN-----PVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATF--GYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNS 876
            ++L+S   WQ I+AE+LG+ +      GS+    +     P+   L  G+A VV+ YC G ISG  +NPAV+  LL  R++ ++R ++Y+  Q LG     G +++S+  K    N               N    K+   ++  + L +    E++ TF+L FTV  +  ++ R   E G   L IG+++T  ++     SG S+NPA SL   +     +    + +GP+LG  LA +  + +F  + S   + + +   D +  +T S
Sbjct:    5 EELRSRQFWQGILAEVLGSLVFVSAVLGSLVPGPDGVSPGPIYPALAAGMATVVLGYCFGEISGAQVNPAVTVALLATRKVDVLRAVVYLVAQCLGGILATGLMYLSLPLKSTAQN-------------YIN----KVPVEMNAGQALGM----EMLATFLLGFTVFSVEDQRRREINEPG--NLAIGLAVTTAIFIAGRFSGASLNPARSLGPAIILGYWEHHWVYWIGPILGAVLAGVSHEFIFAPSASRQKLVACMTCKDIEIVETAS 252
[Close]
BLAST of Aquaporin vs. Ensembl Zebrafish
Match: mipa (major intrinsic protein of lens fiber a [Source:ZFIN;Acc:ZDB-GENE-040801-41])

HSP 1 Score: 102.064 bits (253), Expect = 2.239e-24
Identity = 78/237 (32.91%), Postives = 108/237 (45.57%), Query Frame = 1 
Query:   88 DLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNM----NPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAIL 786
            + +S++ W+++ AE  GT    F G G+         N ++V   FGLA    I  IG ISGGHINPAV+F  LI  Q+SL R   YI  Q LGA         L    VL    + +  +N   + N A   +   I     + +    E+ +T  LV  V    V   R     G A L IG S+ VG   GM  +G  MNPA S A  +  +       + VGP++G  + A+L
Sbjct:    3 EFRSMSFWRAVFAEFYGTMFFVFFGLGAALRWTTGPHNVLQVAFCFGLAAATFIQSIGHISGGHINPAVTFAYLIGSQMSLFRAFFYICAQCLGA---------LAGAAVL----YGVTPTN--MRGNLALNTLQPGI----SMGMATTIEIFLTLQLVVCV--FAVTDERRNGRLGSAALSIGFSVLVGHLLGMYYTGAGMNPARSFAPAVLYRNFINHWVYWVGPMIGAAMGALL 218
[Close]
BLAST of Aquaporin vs. Ensembl Xenopus
Match: ppil2 (peptidylprolyl isomerase like 2 [Source:Xenbase;Acc:XB-GENE-855860])

HSP 1 Score: 109.768 bits (273), Expect = 1.518e-26
Identity = 86/294 (29.25%), Postives = 139/294 (47.28%), Query Frame = 1 
Query:   67 RLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS-----NMNP---VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSIL-HVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLD 921
             + ++ K + +   W+++  E L   +   +  GS  +     N  P   V + L FGL+   ++ C G ISGGHINPAV+  ++  R+ISL + I YI  Q LGA  G   + ++T   V      ++++    TK +SA                 +L EL+ITF LVFT+   C  K ++ +  G   L IG S+ +G    +  +G SMNPA S    +   + +    + VGP+LG  +A  L + V+  +  +  H+K  L      +   + G  K++E  N  QLD
Sbjct:   21 EIMAACKGVWTQEFWKAVTGEFLAMLIFVLLSLGSTINWSPKDNPQPADLVLIALCFGLSIATLVQCFGHISGGHINPAVTVAMVSMRKISLAKSIFYIVAQCLGAIAGAGILYLVTPSDVAGNLGATMVN----TKLSSAH---------------GLLVELIITFQLVFTICASCDPKRKDIS--GSVALAIGFSVAIGHLFAIPYTGASMNPARSFGPAVIMNKWESHWVYWVGPVLGAVIAGALYEYVYCPDPELKNHLKEVLNK----ATQPSKGKYKEVEE-NKSQLD 288
[Close]
BLAST of Aquaporin vs. Ensembl Xenopus
Match: ENSXETT00000039945.1 (aquaporin-4-like [Source:NCBI gene;Acc:100487834])

HSP 1 Score: 105.531 bits (262), Expect = 3.863e-25
Identity = 76/253 (30.04%), Postives = 125/253 (49.41%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS-----NMNP---VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKG-LAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSN 810
            +FK + +   W+S+  E +   +   +G GS  S     +  P   +++ L FGL+ V +++C G ISG H+NPAV+   +  R+I+L + + YI  Q LGA  G   + I+T         F+++ +  +T  N       E +     L   +L E++ITF LVF     C+  S +P  K    P+ IGIS+ +G    +N +G SMNPA SL   +     K    + VGP++G   AA +   ++  +
Sbjct:   12 AFKGVWTQPFWRSVSGEFIAMLIFVLLGLGSTISWGVGDSPQPADLLRISLCFGLSIVTMVHCFGHISGAHLNPAVTIAFVCTRRITLAKSLFYIIAQCLGAISGAGLLYIITP--------FNLIGNLGVTMVN-------ERL----SLGHGLLVEILITFQLVF-----CISASCDPKYKDKYPPIAIGISVIIGHLFAINYTGASMNPARSLGPAVILWNWKSHWIYWVGPIIGAVCAATVYDYIYCPD 240
[Close]
BLAST of Aquaporin vs. Ensembl Xenopus
Match: ENSXETT00000039957.1 (aquaporin-4-like [Source:NCBI gene;Acc:100487834])

HSP 1 Score: 105.531 bits (262), Expect = 4.482e-25
Identity = 75/253 (29.64%), Postives = 126/253 (49.80%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS-----NMNP---VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKG-LAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSN 810
            +FK + +   W+S+  E +   +   +G GS  S     +  P   +++ L FGL+ V +++C G ISG H+NPAV+   +  R+I+L + + YI  Q LGA  G   + I+T         F+++ +  +T  N          +++   H  +L E++ITF LVF     C+  S +P  K    P+ IGIS+ +G    +N +G SMNPA SL   +     K    + VGP++G   AA +   ++  +
Sbjct:   23 AFKGVWTQPFWRSVSGEFIAMLIFVLLGLGSTISWGVGDSPQPADLLRISLCFGLSIVTMVHCFGHISGAHLNPAVTIAFVCTRRITLAKSLFYIIAQCLGAISGAGLLYIITP--------FNLIGNLGVTMVN----------ERLSLGH-GLLVEILITFQLVF-----CISASCDPKYKDKYPPIAIGISVIIGHLFAINYTGASMNPARSLGPAVILWNWKSHWIYWVGPIIGAVCAATVYDYIYCPD 251
[Close]
BLAST of Aquaporin vs. Ensembl Xenopus
Match: ENSXETT00000055415.1 (aquaporin AQPAe.a-like [Source:NCBI gene;Acc:101733960])

HSP 1 Score: 104.375 bits (259), Expect = 7.694e-25
Identity = 78/275 (28.36%), Postives = 123/275 (44.73%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIGFGSV-----FSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCT----------KQSKGLIS--HIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFD 858
            ++L+    W+ ++AE LGTF+L  +  GS       S  + +   L  G   V ++ C G ISG  +NPA++  L+ AR++ L+  + +   Q +GAT       +     V N     + S  N  +                     +  E+  TF L FT+  +   + R+ TE G   L IG S+T G      +SGGSMNPA SL   + T          KQ+K L++  + +GP+LG FLA    +  F S+ S   + + L   D +
Sbjct:    5 EELRRCRFWRLVLAETLGTFMLVTVVLGSSCLGLRVSRSDSLLPALAAGFTVVSLVQCFGEISGAQLNPAITSALVCARKLDLLHGMAFAVAQCVGATCASALFYVCMPESVCNQLVTRVSSEGNAGQ--------------------ALAMEVFATFQLAFTIFAVDDRRRRDLTEPG--SLAIGFSVTAGALTAGQVSGGSMNPARSLGPALVTGIWEHHWASLKQNKFLLTLVYWIGPVLGAFLAGASYEFFFASSASREKLVACLTCKDIE 257
[Close]
BLAST of Aquaporin vs. Ensembl Xenopus
Match: aqp5 (aquaporin 5 [Source:NCBI gene;Acc:100491662])

HSP 1 Score: 102.834 bits (255), Expect = 3.060e-24
Identity = 79/237 (33.33%), Postives = 117/237 (49.37%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIGFGSV--FSNMNP--VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAI 783
            ++L SL  W++I AE L T +  F G GS   +    P  +++ L FGL    ++  +G ISG HINPAV+   L+  QISLIR   YI  Q+LG   G     IL          + ++S N   + N A   ++ NI       +  + E+++TF LV  +       SR     G   L IG+S+T+G   G+  +G SMNPA S A  +  ++        +GPL GG LA++
Sbjct:    3 RELCSLVFWKAIFAEFLATLIFVFFGLGSALRWPAALPTVLQISLAFGLVIGTLVQSVGHISGAHINPAVTMSFLVGSQISLIRAFFYIIAQLLGGLAG---AGIL----------YGVVSPN--VRGNLAINTLSNNITP----GVAFVVEMILTFQLVMCI--FASTDSRREDNVGSPALSIGLSVTLGHLVGIYFTGCSMNPARSFAPAVVVRRFTNHWVFWIGPLAGGMLASL 218
[Close]
BLAST of Aquaporin vs. Ensembl Mouse
Match: Aqp4 (aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387])

HSP 1 Score: 112.464 bits (280), Expect = 8.861e-28
Identity = 84/291 (28.87%), Postives = 136/291 (46.74%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPVKV-----GLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L T +   +G GS  +   + NP+ V      L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     + +   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +          + VGP++G  LA  L + VF  ++ +       FS    +  T     +  +N + ++ + +
Sbjct:    3 AFKGVWTQAFWKAVSAEFLATLIFVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWANHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSK--AAQQTKGSYMEVEDNRSQVETEDL 270
[Close]
BLAST of Aquaporin vs. Ensembl Mouse
Match: Aqp4 (aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387])

HSP 1 Score: 112.464 bits (280), Expect = 8.861e-28
Identity = 84/291 (28.87%), Postives = 136/291 (46.74%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPVKV-----GLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L T +   +G GS  +   + NP+ V      L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     + +   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +          + VGP++G  LA  L + VF  ++ +       FS    +  T     +  +N + ++ + +
Sbjct:    3 AFKGVWTQAFWKAVSAEFLATLIFVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWANHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSK--AAQQTKGSYMEVEDNRSQVETEDL 270
[Close]
BLAST of Aquaporin vs. Ensembl Mouse
Match: Aqp4 (aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387])

HSP 1 Score: 112.464 bits (280), Expect = 8.861e-28
Identity = 84/291 (28.87%), Postives = 136/291 (46.74%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPVKV-----GLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L T +   +G GS  +   + NP+ V      L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     + +   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +          + VGP++G  LA  L + VF  ++ +       FS    +  T     +  +N + ++ + +
Sbjct:    3 AFKGVWTQAFWKAVSAEFLATLIFVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWANHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSK--AAQQTKGSYMEVEDNRSQVETEDL 270
[Close]
BLAST of Aquaporin vs. Ensembl Mouse
Match: Aqp4 (aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387])

HSP 1 Score: 112.464 bits (280), Expect = 8.861e-28
Identity = 84/291 (28.87%), Postives = 136/291 (46.74%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPVKV-----GLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L T +   +G GS  +   + NP+ V      L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     + +   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +          + VGP++G  LA  L + VF  ++ +       FS    +  T     +  +N + ++ + +
Sbjct:    3 AFKGVWTQAFWKAVSAEFLATLIFVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWANHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSK--AAQQTKGSYMEVEDNRSQVETEDL 270
[Close]
BLAST of Aquaporin vs. Ensembl Mouse
Match: Aqp4 (aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387])

HSP 1 Score: 112.464 bits (280), Expect = 8.861e-28
Identity = 84/291 (28.87%), Postives = 136/291 (46.74%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPVKV-----GLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L T +   +G GS  +   + NP+ V      L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     + +   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +          + VGP++G  LA  L + VF  ++ +       FS    +  T     +  +N + ++ + +
Sbjct:    3 AFKGVWTQAFWKAVSAEFLATLIFVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWANHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSK--AAQQTKGSYMEVEDNRSQVETEDL 270
[Close]
BLAST of Aquaporin vs. UniProt/SwissProt
Match: sp|G5CTG2|AQP5_MILTA (Aquaporin-5 OS=Milnesium tardigradum OX=46460 GN=AQP5 PE=2 SV=1)

HSP 1 Score: 131.724 bits (330), Expect = 2.696e-34
Identity = 89/255 (34.90%), Postives = 130/255 (50.98%), Query Frame = 1 
Query:   76 SSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPV-------KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSI 819
            SS +DL  +  W+++ AE +GT +L +IG G+  ++           +V L FGL    +++ I  +SGGHINPAVS G L+ R+ISL+RF+LY+  Q  GA  G           +L  S F  +        + A    TEN   +      IL E +ITFVLVFTV   C  K  +   KG  PL IGI++ +     + ++G SMNPA SL   +            VGP+LGG +A +L  + F ++ S+
Sbjct:    8 SSIEDLAKIQFWKALGAEFIGTAVLVYIGCGAAVTSTPDANRDAFVTRVSLAFGLTVATMVWAICGVSGGHINPAVSLGFLVTRRISLVRFLLYVAFQCSGAVAG---------AALLYASTFDSVKRGGFGTNSMA----TENGQYLISPAQGILIEAIITFVLVFTVFATCDAKRSD--LKGSGPLAIGIAVLISHLVAIPLTGTSMNPARSLGPAVLIGFWTDHWVFWVGPMLGGAVAGLLYDMAFAADASL 247
[Close]
BLAST of Aquaporin vs. UniProt/SwissProt
Match: sp|Q9V5Z7|AQP_DROME (Aquaporin OS=Drosophila melanogaster OX=7227 GN=Drip PE=2 SV=2)

HSP 1 Score: 115.546 bits (288), Expect = 1.445e-28
Identity = 81/250 (32.40%), Postives = 123/250 (49.20%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLF 843
            ++  +W+ ++ EL+GTF L F+G GS  S   P ++   FGL    I   +G +SG HINPAV+ G LI  +IS+++   YI VQ +GA  G   I +   G          ++  +L            + D   +    +L E +ITF+LVF V++   +  R    KG APL +G++I  G  C + +SG SMNPA S    +          + VGP+ GG LA I+ +L+F          S+ F
Sbjct:   18 ENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP-QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDG----------VAGGDLG---------VSSFDPSLNCAQAVLIEALITFILVF-VVKAVSDPGRQDI-KGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTYHWVYWVGPIAGGLLAGIIYRLIFKVRKGDDETDSYDF 245
[Close]
BLAST of Aquaporin vs. UniProt/SwissProt
Match: sp|Q7PWV1|AQP_ANOGA (Aquaporin AQPAn.G OS=Anopheles gambiae OX=7165 GN=AGAP008842 PE=3 SV=4)

HSP 1 Score: 112.464 bits (280), Expect = 2.102e-27
Identity = 77/240 (32.08%), Postives = 119/240 (49.58%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSV--FSNMNPV--KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVF 801
            ++ N+W+ ++AE LGTF L  IG GS   +++ +P   ++   FGL    +    G +SG HINPAV+ GL++   +S+++   YI  Q +GA  G   I   T  +V+     + ++    T                      +L E +ITF+LVF V  +C   +R    KG APL IG+SIT G    +  +G SMNPA S    +       L  + VGP++GG +A  + +L F
Sbjct:   18 ENRNIWRMLVAEFLGTFFLVAIGIGSTTGWTDYSPTLTQIAFTFGLVVATLAQAFGHVSGCHINPAVTIGLIVTADVSILKGAFYIVSQCIGAIAGAAVIKAATPSEVVGGLGVTGIAPGLSTG-------------------QGVLIEALITFMLVFVVHGVC--DNRRTDVKGSAPLAIGLSITAGHLAAIKYTGASMNPARSFGPAVVMGNYTDLWVYWVGPIVGGIVAGAVYRLFF 236
[Close]
BLAST of Aquaporin vs. UniProt/SwissProt
Match: sp|Q9NHW7|AQP_AEDAE (Aquaporin AQPAe.a OS=Aedes aegypti OX=7159 GN=AAEL003512 PE=2 SV=2)

HSP 1 Score: 111.694 bits (278), Expect = 3.384e-27
Identity = 81/241 (33.61%), Postives = 116/241 (48.13%), Query Frame = 1 
Query:   94 KSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPV--KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVF 801
            ++ N+W+ ++AE LGTF L  IG GS      +  P   ++   FGL    +    G +SG HINPAV+ GL+I   IS+++   YI  Q +GA  G   I      K   PS   ++    +T            ID        ++ E +ITF+LVF V  +C   +R    KG APL IG+SIT G    +  +G SMNPA S    +          + VGP++GG LA  + +L F
Sbjct:   18 ENRNIWRMLVAEFLGTFFLVSIGIGSTMGWGGDYAPTMTQIAFTFGLVVATLAQAFGHVSGCHINPAVTIGLMITADISILKGAFYIVSQCVGAIAGAALI------KAATPS--DVIGGLGVT-----------GIDPRLTAGQGVMIEALITFILVFVVHGVC--DNRRSDIKGSAPLAIGLSITAGHLSAIKYTGASMNPARSFGPAVVMGNWTDQWVYWVGPIVGGILAGAVYRLFF 237
[Close]
BLAST of Aquaporin vs. UniProt/SwissProt
Match: sp|P55088|AQP4_MOUSE (Aquaporin-4 OS=Mus musculus OX=10090 GN=Aqp4 PE=1 SV=2)

HSP 1 Score: 112.464 bits (280), Expect = 8.960e-27
Identity = 84/291 (28.87%), Postives = 136/291 (46.74%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS---NMNPVKV-----GLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            +FK + +   W+++ AE L T +   +G GS  +   + NP+ V      L FGL+   ++ C G ISGGHINPAV+  ++  R+IS+ + + YI  Q LGA  G   + ++T   V+     + +   NLT  +                   +L EL+ITF LVFT+   C  K  + T  G   L IG S+ +G    +N +G SMNPA S    +          + VGP++G  LA  L + VF  ++ +       FS    +  T     +  +N + ++ + +
Sbjct:   25 AFKGVWTQAFWKAVSAEFLATLIFVLLGVGSTINWGGSENPLPVDMVLISLCFGLSIATMVQCFGHISGGHINPAVTVAMVCTRKISIAKSVFYIIAQCLGAIIGAGILYLVTPPSVVGGLGVTTV-HGNLTAGHG------------------LLVELIITFQLVFTIFASCDSKRTDVT--GSIALAIGFSVAIGHLFAINYTGASMNPARSFGPAVIMGNWANHWIYWVGPIMGAVLAGALYEYVFCPDVELKRRLKEAFSK--AAQQTKGSYMEVEDNRSQVETEDL 292
[Close]
BLAST of Aquaporin vs. TrEMBL
Match: A0A0G4DCR1 (Aquaporin OS=Dugesia japonica OX=6161 GN=aquaporin PE=2 SV=1)

HSP 1 Score: 336.65 bits (862), Expect = 4.726e-111
Identity = 168/283 (59.36%), Postives = 211/283 (74.56%), Query Frame = 1 
Query:   55 MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNS-ADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMEN 900
            M   RL SS KD+K+ N WQS++AE LGTF+L F+GFG+ ++NMNPVK+GLGFGLAG V I CIGPISG HINPAVS GLL+ARQISLIR+I Y   QI+GAT G+  IS ++ G+VL  S++ I    N T   S  + +I E I ++ + +LKI+CELVITFVLVFTVMRLCVEK R+PTEKG+APL IG+SIT GVYCGMNISGGSMNPA SL K+   K    +++HI+GPLLGG LA + QQ+ FTS+LS+ H+KS+LF  +F+ H  N   S    +
Sbjct:    1 MKTFRLESSIKDVKTFNFWQSLVAEFLGTFILVFVGFGTAYNNMNPVKLGLGFGLAGAVAIVCIGPISGAHINPAVSCGLLVARQISLIRYIFYTIFQIIGATAGFGLISGVSSGEVLYKSYYKI----NFTSSPSLGEARIDEVIHRVTNPYLKIICELVITFVLVFTVMRLCVEKRRSPTEKGIAPLFIGLSITAGVYCGMNISGGSMNPAASLGKYFF-KGGTTIMTHIIGPLLGGALAGVSQQMFFTSDLSMSHIKSYLFDSEFEDHSDNYEPSSSRHD 278
[Close]
BLAST of Aquaporin vs. TrEMBL
Match: A0A0G4DC26 (Aquaporin OS=Dugesia japonica OX=6161 PE=2 SV=1)

HSP 1 Score: 221.861 bits (564), Expect = 1.032e-65
Identity = 124/263 (47.15%), Postives = 167/263 (63.50%), Query Frame = 1 
Query:   61 QIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSH 849
            ++R+ SS +D+ + N W ++ AE  GTF+L FIG G+ +SN   V   L FGL G + IY  GPISGG+INPAVS GLLIARQIS IR +LY+  Q++GA      ISI+T  +  N +H     S+    ++ A                 + CE+VI+F+LVFTVMR+CVEKSR+  E+GLA L+IGISI VG+ CG NISGGSMNPA +L   +   +   +  +I GPL+GG LA ++QQL+FTS LS    K +LF +
Sbjct:   12 KLRIWSSLQDITTRNFWTALFAECCGTFILVFIGLGACYSNGGLVGAALAFGLGGSIGIYVSGPISGGNINPAVSIGLLIARQISFIRCMLYMLFQVIGALLAAKCISIMTY-ETFNKTHGI---SHPSVPWDKA-----------------LFCEIVISFILVFTVMRMCVEKSRSEVERGLAALLIGISIVVGILCGGNISGGSMNPARTLGPAIVNNKLNNVWIYIAGPLIGGILAGLVQQLLFTSELS----KDYLFDY 249
[Close]
BLAST of Aquaporin vs. TrEMBL
Match: A0A0G4DCJ9 (Aquaporin OS=Dugesia japonica OX=6161 GN=aquaporin PE=2 SV=1)

HSP 1 Score: 210.305 bits (534), Expect = 8.583e-63
Identity = 105/149 (70.47%), Postives = 123/149 (82.55%), Query Frame = 1 
Query:  475 ITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLD 921
            ITE IDKI+ L+L+I CE+VI+FVLVFTVMRLCVEKSR+ TEKGLAPLIIGISIT+GVYCGMNISGGSMNPAVS  K++CT  S G+ SHI+GPL GGFLA ILQQLVF+SNLS  H+KS+LFS +FD+      +S   E  NDIQL+
Sbjct:   48 ITEKIDKIESLNLRIFCEMVISFVLVFTVMRLCVEKSRSTTEKGLAPLIIGISITIGVYCGMNISGGSMNPAVSFGKYLCTG-STGITSHIIGPLSGGFLAGILQQLVFSSNLSFDHIKSYLFSSEFDND-----ESSNNERQNDIQLN 190
[Close]
BLAST of Aquaporin vs. TrEMBL
Match: A0A0B7ASU0 (Uncharacterized protein OS=Arion vulgaris OX=1028688 GN=ORF138595 PE=3 SV=1)

HSP 1 Score: 144.436 bits (363), Expect = 1.743e-36
Identity = 96/271 (35.42%), Postives = 143/271 (52.77%), Query Frame = 1 
Query:   70 LASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS------NMNPV-KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDS 861
            + +S +D+ SL LW+ I+AE +GT LL  +G GS  +        +PV ++ L FGL+   I++ I  ISGGHINPAV+  +L AR+ISL + + +I  Q++GA  G   +  LT      PS +      NL             +++  +L   I  E+ ITFVLVFTV   C  K R+    G  PL IG ++T+     +N +G SMN A S    +   Q      + +GP++GG +A +L + VF  N S+L  K+ L S D+D 
Sbjct:    1 MVTSLEDISSLRLWKGIVAEFVGTLLLTLVGCGSCINLKGTANTTSPVVQIALSFGLSVATIVWSIAHISGGHINPAVTVAMLAARKISLAKGVFFILFQLIGAVVGAGILFGLT------PSAY----HENLG---------MTTVNREINLGQAIGVEMFITFVLVFTVFASCDSKRRDL--NGSTPLSIGFAVTMCHLWAINYTGSSMNTARSFGPALVMGQWDNHWVYWLGPIMGGVIAGLLYEHVFACNASLLKAKACLLSSDYDD 250
[Close]
BLAST of Aquaporin vs. TrEMBL
Match: A0A2T7NJV9 (Uncharacterized protein OS=Pomacea canaliculata OX=400727 GN=C0Q70_19620 PE=3 SV=1)

HSP 1 Score: 144.821 bits (364), Expect = 4.892e-36
Identity = 98/274 (35.77%), Postives = 147/274 (53.65%), Query Frame = 1 
Query:   55 MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS-NMNP---VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSH 864
            +  +R+A+S +D+ SL LW+ IIAE +GT LL  +G GS  +    P   V++ L FGL+   I++ IG ISGGHINPAV+  LL AR+ISL + + ++  Q++GA  G   +  LT      PS +     N L         +++ ID  K L ++I     ITFVLVFTV      K ++    G  PL IG+S+T+     +  +G SMN A S    + T        + VGP+ GG LA +L + +F  N S+  V++ + + D+D  
Sbjct:   47 LQTVRMATSLEDITSLRLWKGIIAEFVGTLLLVLVGCGSCINLGSEPPSTVQISLCFGLSVATIVWNIGHISGGHINPAVTLALLAARKISLAKAVFFVIFQLVGAVVGAGILMGLT------PSAYHGDFGNTL---------VSKKIDPGKALGVEIF----ITFVLVFTVFASVDSKRKDI--NGSTPLSIGLSVTMCHLFAIQYTGSSMNTARSFGPALVTGTWDNHWVYWVGPISGGVLAGLLYEYLFAVNASLNKVRACMLTSDYDDE 299
[Close]
BLAST of Aquaporin vs. Ensembl Cavefish
Match: AQP4 (aquaporin-4 [Source:NCBI gene;Acc:103027636])

HSP 1 Score: 117.472 bits (293), Expect = 1.643e-29
Identity = 88/287 (30.66%), Postives = 140/287 (48.78%), Query Frame = 1 
Query:   76 SSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS----NMNP-----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTND 909
            ++FK + +   W+++  E L T +   +  GS  +      NP     V + L FGL+   ++ C G ISGGHINPAV+  +++ R++SL + + YI  Q LGA  G   + ++T      PS  ++     +T  N           +I   H  ++ EL+ITF L+FTV   C  K  +   KG A L IGI++ +G    +  +G SMNPA S    + T   +    + VGP+LGG LAA L + ++  +  +      +F  D       SG  K++E  N+
Sbjct:   32 AAFKGIWTKAFWRAVSGEFLATLIFVLLSLGSTINWASGTENPPPADLVLISLCFGLSIATMVQCFGHISGGHINPAVTAAMVVTRKMSLAKALFYILAQCLGAIVGAGLLFLVT------PS--AVRGGMGVTTVNP----------RISVGH-ALVVELLITFELIFTVFSTCDHKRSD--LKGSASLAIGIAVLIGHLFAIPYTGASMNPARSFGPAVVTWSWESHWVYWVGPILGGVLAAALYEYLYCPDPDLKTRCKAMFKDD-------SGKYKEVECPNN 290
[Close]
BLAST of Aquaporin vs. Ensembl Cavefish
Match: AQP4 (aquaporin-4 [Source:NCBI gene;Acc:103027636])

HSP 1 Score: 117.472 bits (293), Expect = 2.007e-29
Identity = 88/287 (30.66%), Postives = 140/287 (48.78%), Query Frame = 1 
Query:   76 SSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS----NMNP-----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTND 909
            ++FK + +   W+++  E L T +   +  GS  +      NP     V + L FGL+   ++ C G ISGGHINPAV+  +++ R++SL + + YI  Q LGA  G   + ++T      PS  ++     +T  N           +I   H  ++ EL+ITF L+FTV   C  K  +   KG A L IGI++ +G    +  +G SMNPA S    + T   +    + VGP+LGG LAA L + ++  +  +      +F  D       SG  K++E  N+
Sbjct:   33 AAFKGIWTKAFWRAVSGEFLATLIFVLLSLGSTINWASGTENPPPADLVLISLCFGLSIATMVQCFGHISGGHINPAVTAAMVVTRKMSLAKALFYILAQCLGAIVGAGLLFLVT------PS--AVRGGMGVTTVNP----------RISVGH-ALVVELLITFELIFTVFSTCDHKRSD--LKGSASLAIGIAVLIGHLFAIPYTGASMNPARSFGPAVVTWSWESHWVYWVGPILGGVLAAALYEYLYCPDPDLKTRCKAMFKDD-------SGKYKEVECPNN 291
[Close]
BLAST of Aquaporin vs. Ensembl Cavefish
Match: aqp1a.1 (aquaporin FA-CHIP [Source:NCBI gene;Acc:103038005])

HSP 1 Score: 109.768 bits (273), Expect = 3.086e-27
Identity = 84/286 (29.37%), Postives = 138/286 (48.25%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMN------PVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKV--LNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVK-SFLFSHDFDSHDTN-SGDSKKMENTN 906
            + K+LKS   W++++AEL+G  L  F+   +   N N       VKV L FGL+   +   +G ISG H+NPAV+ G+L++ QISL+R +LYI  Q+LGA         +  G V  + P + + L  N L            NI  ++ + +    E++ TF LV  V+    ++ R+    G  PL IG+S+ +G    ++ +G  +NPA S    +          + VGP+ GG  AA++   +    +     +   L S     +D N + D+  +E T+
Sbjct:    2 AMKELKSKAFWRAVLAELVGMTLFIFLSIAAAVGNTNNSNPDQEVKVALAFGLSIATLAQSLGHISGAHLNPAVTLGMLVSCQISLLRAVLYILAQMLGAA--------VASGVVYGVRPENNTALGLNAL-----------NNITPVQGIGV----EMLATFQLVLCVLAATDKRRRD--VMGSVPLAIGLSVALGHLTAISFTGCGINPARSFGPAVILGDFTNQWVYWVGPMCGGVAAALIYDFLLYPKMEDFPERIRVLVSGPPTDYDVNGTDDAPAVEMTS 262
[Close]
BLAST of Aquaporin vs. Ensembl Cavefish
Match: aqp1a.2 (aquaporin-1-like [Source:NCBI gene;Acc:103041890])

HSP 1 Score: 108.227 bits (269), Expect = 1.175e-26
Identity = 77/239 (32.22%), Postives = 118/239 (49.37%), Query Frame = 1 
Query:   88 DLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMN------PVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAIL 786
            + +S   W+ ++AE +G  L  FIG  S   N +       VKV LGFGLA   +   +G +SG H+NPAV+ G L++ +IS ++ +LY+  QILGA    L +S LT G+       + L  N+L            N+  ++   +    E + TF LV  V  +    +R     G APL IG+S+ +G    ++ +G  +NPA S    +     K    +  GP+LGG  AA+L
Sbjct:    5 EFRSGWFWRGVMAEFVGMILFIFIGLASAVGNKHNSGPDQEVKVALGFGLAVATLAQSLGHVSGAHLNPAVTVGALVSCRISALKALLYVSAQILGAVLASLIMSRLTPGE-------TSLGVNSLAP----------NLTPVQGFGI----EFLATFQLVLCV--VATTDNRRNDVTGSAPLAIGLSVGLGHLAAISYTGCGINPARSFGPALIMNSFKDHWVYWAGPMLGGVAAALL 220
[Close]
BLAST of Aquaporin vs. Ensembl Cavefish
Match: ENSAMXT00000043631.1 (aquaporin-4-like [Source:NCBI gene;Acc:103025508])

HSP 1 Score: 106.686 bits (265), Expect = 5.842e-26
Identity = 80/298 (26.85%), Postives = 139/298 (46.64%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGT--FLLAFIGF---GSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFG----YLFISILTKGKVLNPSHFSILSSNNLTKFNSADY--KITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDI-----QLDKIE 930
            ++++S   W+S++AE+L +  F+ A +G    GS   ++ P+   L  G+A V + +C G ISG  +NPAV+  LL  R++ ++R ++Y+  Q LGA  G    YL + +                     KF +  Y  K+   ++  + L      E++ TF L FTV  +  ++ R  +E G   + IG S++ G++    ISGG +NPA SL   +     +      +GP+LG  LA +  +  F  + S   + + L   D +  +T S     +           Q +K+E
Sbjct:    5 EEVRSRQFWRSMLAEILASLVFVSAVLGSSLPGSEGPSLGPIYPALAAGMATVGLGHCFGEISGAQVNPAVTLALLATRRLDVLRAVVYVVAQCLGAILGAGIFYLVLPL---------------------KFTAEIYVNKVPMEVNAGQALG----AEMLATFQLAFTVFSVEDQRRREGSEPG--NIAIGFSVSAGIFIAGKISGGCLNPARSLGPAIIAGYWEHHWVFWIGPVLGAVLAGVSHEFFFAPSASRQKLVACLTCKDIEIVETASVSRSSLSTVTQTAMRAKQTNKLE 275
[Close]
BLAST of Aquaporin vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004947.1 (pep scaffold:Pmarinus_7.0:GL478425:219996:222130:-1 gene:ENSPMAG00000004489.1 transcript:ENSPMAT00000004947.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 77.411 bits (189), Expect = 6.736e-18
Identity = 38/92 (41.30%), Postives = 59/92 (64.13%), Query Frame = 1 
Query:   88 DLKSLNLWQSIIAELLGTFLLAFIGFGSVF------SNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFV 345
            +L+S   W+++ AE L T  L  +G GS         +++ V+V L FGLA   ++ C+G +SGGH+NPAV+FGLL+ R+I ++R +LY  V
Sbjct:    8 ELRSRPFWRAVFAEFLATAALVALGIGSTLRWGRADGSVDVVRVSLAFGLAVATLVQCVGHVSGGHLNPAVTFGLLVGRKILIVRGLLYAAV 99
[Close]
BLAST of Aquaporin vs. Ensembl Sea Lamprey
Match: aqp3b (aquaporin 3b [Source:ZFIN;Acc:ZDB-GENE-040724-66])

HSP 1 Score: 67.0106 bits (162), Expect = 1.043e-12
Identity = 66/248 (26.61%), Postives = 111/248 (44.76%), Query Frame = 1 
Query:  121 IAELLGTFLLAFIGFGSVFS-------NMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKI----LCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISIT-VGVYCGMNISGGSMNPAVSLAKFMCTK---------QSKGLISH--IVGPLLGGFLAAILQQL 795
            +AE +GT++L   G GSV             + + L FG A  + ++    +SGGH+NPAV+F   +  +    +  LY+  Q+LGA  G         G V    + + L + N     +   ++          HL +    + +L+ T  L+  +M + ++K  NP  KG+ P IIG+ +  +G+  G N +G ++NPA  L   + T           S    S   +V P++GG L A   +L
Sbjct:   26 MAEFVGTYILVLFGCGSVAQVELSGGLKGQFLTINLAFGFAVTMGLHAAAGVSGGHLNPAVTFAFAVLGRFEWHKLPLYMLAQLLGAFMG--------AGTVFGLYYDAFLFAAN----GNYTIQLAGVFATYPSEHLSLGNGFVDQLIGTAALLVCIMAV-IDKRNNPAPKGMQPYIIGLVVVLIGLSMGFN-AGYAVNPARDLGPRLFTSIAGWGWAVFSSGNYWSWVPVVAPMIGGVLGAFFYEL 259
[Close]
BLAST of Aquaporin vs. Ensembl Sea Lamprey
Match: aqp8a.1 (aquaporin 8a, tandem duplicate 1 [Source:ZFIN;Acc:ZDB-GENE-040912-106])

HSP 1 Score: 56.225 bits (134), Expect = 1.557e-9
Identity = 57/186 (30.65%), Postives = 86/186 (46.24%), Query Frame = 1 
Query:  112 QSIIAELLGTFLLAFIGFGSVFSN---MNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCV-EKSRNPTEKGLAPLIIGISITVGVYCG 657
            Q + AEL+G+F   FIG  SV +N      ++  L  GLA  + I  +G +SGGH NPAV+ G+ +   +SL   I Y   Q++G   G L    L +G V   +  +   +  +     A             L   +L E  ++ +LV  V+   V E+S +P    LAP  IG  +TV +  G
Sbjct:   43 QPVAAELVGSFFFIFIGCLSVITNPSDTGALQPALAHGLALGLCIAVLGKLSGGHFNPAVTAGVAVVGGVSLRLVIPYWVSQLVGGMLGAL----LARGVVGEEAFAASSGAAFVPPEAVA-------------LGRAVLAETFLSALLVLAVVMGAVNERSSSP----LAPFCIGFVVTVDILAG 207
[Close]
BLAST of Aquaporin vs. Ensembl Sea Lamprey
Match: AQP4 (aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637])

HSP 1 Score: 47.7506 bits (112), Expect = 6.865e-7
Identity = 35/136 (25.74%), Postives = 57/136 (41.91%), Query Frame = 1 
Query:  517 ILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSK-KMENTNDIQLD 921
            +L E++ITF L FTV   C      P   G   + +G+++  G    +  +G SMNPA SL   + +        + +GP+LG  LA    + +   +  I       FS    +   + G    +ME     + D
Sbjct:   11 LLIEMMITFFLSFTVFSTCDPNRPEPRIPGS--VAVGVAVIAGHLFAIPYTGASMNPARSLGPAIVSANWDHHWLYWIGPMLGAVLAGAAYEYLLCPDPEIKRRLKEAFSRASPARQQSLGAKYVEMEEAGGGRED 144
[Close]
BLAST of Aquaporin vs. Ensembl Yeast
Match: AQY1 (Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance [Source:SGD;Acc:S000006396])

HSP 1 Score: 56.9954 bits (136), Expect = 1.438e-9
Identity = 63/246 (25.61%), Postives = 105/246 (42.68%), Query Frame = 1 
Query:  193 VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQ-SKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKI 927
            + + +GFG + +  I+C   +SGG +NPA+S  L +AR +S  R ++    QI+         S +T G+VL  +   +  S                  + + L L    E+  T +L  TV+   VEK        +A L IGIS+ +        +G  +NPA SL   +  +        + +G LLG  LA  + QL     L IL   +++ +    S  T     KK E ++   + ++
Sbjct:   92 IMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTPGEVLFANSLGLGCS------------------RTRGLFL----EMFGTAILCLTVLMTAVEKRET---NFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQL-----LQILDYTTYVTAEKAAS--TKEKAQKKGETSSSSAVAEV 305
[Close]
BLAST of Aquaporin vs. Ensembl Yeast
Match: AQY3 (Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol [Source:SGD;Acc:S000001840])

HSP 1 Score: 53.5286 bits (127), Expect = 3.076e-8
Identity = 37/105 (35.24%), Postives = 48/105 (45.71%), Query Frame = 1 
Query:  103 NLWQSI-------IAELLGTFLLAFIGFGSVFSNMNPVKVGLG---------FGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFG 369
            N W  I        AE LGT +L   G G        V  G G         +G   ++ +Y  G ISGGHINPAV+  + I R+    +  +YI  QI+GA FG
Sbjct:  338 NFWAKIRYHMREPFAEFLGTLVLVIFGVGGNLQAT--VTKGSGGSYESLSFAWGFGCMLGVYVAGGISGGHINPAVTISMAIFRKFPWKKVPVYIVAQIIGAYFG 440
[Close]
BLAST of Aquaporin vs. Ensembl Nematostella
Match: EDO41164 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S515])

HSP 1 Score: 80.4925 bits (197), Expect = 4.218e-17
Identity = 70/246 (28.46%), Postives = 104/246 (42.28%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNP----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSN 810
            K+L S   W  I+AE + T L   I  G+   N +       + L  GLA      C+  +S G  NPA++ G LI  + +L++ I YI  Q+ G+  G   I  +        S  S+ +SN      S D  I + +            E+  TF+LV  V     +  R        PL IGI + + +   + ISGGSMNPA S    +     K    + +GP+ G  LA++    VF   
Sbjct:    9 KELYSRRFWTEILAEFIITSLFVSIVCGTALQNWSTPPTLTHMALNSGLAAGTFAMCMWDVSSGLFNPALTIGFLITGKKTLLQTIFYIMAQLTGSICGAAAIYGMA-------SQHSVEASNLAVNARSPDVSIGQAVGM----------EIWATFILVLIVFA-AGDSDRQHMRGYGPPLSIGIVVFINLSLTIPISGGSMNPARSFGPAVVMNSWKDHWMYWIGPIAGSCLASLCYHHVFAQR 236
[Close]
BLAST of Aquaporin vs. Ensembl Nematostella
Match: EDO28361 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6P4])

HSP 1 Score: 67.0106 bits (162), Expect = 7.559e-13
Identity = 74/243 (30.45%), Postives = 110/243 (45.27%), Query Frame = 1 
Query:  112 QSIIAELLGTFLLAFIGFGSVFSN------MNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENID-----KIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTS 807
            +  +AE +GTF L F G G++  N      +  + + L FG+    +IY  G ISG HINP+V+  L+I +       + YI  QILGA                      IL+S+ L       +  TEN+         +L    + E V+TF L+ T++ +  +K        +  LIIGI +T  +     ISGGS NPA SLA  + +     L  +I  P LG    AI+  L++ S
Sbjct:    2 KKYVAEFIGTFALVFCGTGAIIVNEQSNGSLGLIGIALTFGIIISAMIYVFGNISGTHINPSVTIALVIGKLTLKRDALFYILAQILGA----------------------ILASSLL------KFMFTENLSLGATIPSGELLQSFILEFVLTFFLMLTILGITSKKEFT----NIVGLIIGIVVTGIILFAGPISGGSFNPARSLAPALISGNFTALWIYIAAPTLG----AIVAMLIWNS 208
[Close]
BLAST of Aquaporin vs. Ensembl Nematostella
Match: EDO41124 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S514])

HSP 1 Score: 63.1586 bits (152), Expect = 2.142e-11
Identity = 37/110 (33.64%), Postives = 57/110 (51.82%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPV------KVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTK 396
            ++  + N W S+ AEL+ T L  F+  GS  +  +P+       + L FGL+   +  C   ISGGHINPAV+   +I R++S +R   Y+  Q+ G   G   +  LT 
Sbjct:    4 REFLTGNFWASVWAELMATALFVFLTTGSAIT-WDPLLPPSIEHISLSFGLSIATLAMCTAHISGGHINPAVTISFMIVRKVSFLRGAFYVIGQVGGGIAGSAMLYGLTP 112
[Close]
BLAST of Aquaporin vs. Ensembl Nematostella
Match: EDO45027 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RU63])

HSP 1 Score: 55.4546 bits (132), Expect = 9.677e-9
Identity = 58/218 (26.61%), Postives = 96/218 (44.04%), Query Frame = 1 
Query:  112 QSIIAELLGTFLLAFIGFGSVFSNM--NPVK-----VGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFIL-YIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHL----KILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISI-TVGVYCGMNISGGSMNPAVSLAKFMCTKQS 726
            +S +AE + TF+L   G GS+   +  N  K     V   +G+   +  Y  G ISG H+NPAV+    +AR++   RF+L Y   Q+LGA              V    H ++   +N  + N    K T  +                + V   +L+   +   ++K  N  +KG AP++IG+++  +G   G N  G ++NPA  L   + T  +
Sbjct:   19 RSFLAEFIATFILVSFGCGSIAQMLLSNETKGTFFSVNFSWGIGVTLGCYWAGGISGAHMNPAVTLAFAVARRLPW-RFVLVYCLAQLLGA--------FAASACVYGVYHDALNHFDNGIR-NVTGEKATAGVWATYPQPWLSTQGAFGDQVFGTMLLTGCIFAILDKHNNAPDKGTAPILIGLTVFCIGTAFGFN-CGYAINPARDLGPRLFTAMA 225
[Close]
BLAST of Aquaporin vs. Ensembl Nematostella
Match: EDO41149 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S565])

HSP 1 Score: 50.8322 bits (120), Expect = 2.122e-7
Identity = 57/225 (25.33%), Postives = 102/225 (45.33%), Query Frame = 1 
Query:  127 ELLGTFLLAFIGFGSV-----FSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVE-KSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAI 783
            ELL + +  F+   S      F   +   + L  GL    ++  +  ++GG INPAV+  +++ R++  +  ++++F Q+LG   G   +  LT      PS  SI  S  +T   +   ++ + +            E ++TF+LVF ++    E K+    EK  A   +G  + +    G+  +G SMNPA SL   +     +    + VGP  G  LA++
Sbjct:    1 ELLASHVFVFLVCASCVSWPHFQAPSVQHIALTAGLTTSTLVMVMSHVTGGQINPAVAVAMVVTRRVKPVHGLVFVFSQVLGGLLGAALLFGLT------PS--SIRGSLGMT-VPAPTIQVGQAVAM----------ETILTFLLVFGILAATDERKALKGYEKAAA---VGFCVFICHMAGIPFTGCSMNPARSLGPAVVMDHWRHHWVYWVGPFAGSILASL 203
[Close]
BLAST of Aquaporin vs. Ensembl Medaka
Match: ENSORLT00000043818.1 (aquaporin-4 [Source:NCBI gene;Acc:101156496])

HSP 1 Score: 113.235 bits (282), Expect = 2.099e-28
Identity = 77/269 (28.62%), Postives = 133/269 (49.44%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLL--AFIGF---GSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNS 876
            +DL+S   W +I+AELLGT +L  A +G    G   + + P+   +  G+A + + +C G ISG  +NP+++  LL  R++ ++R ++YI  Q  GA     F+ +    K     HF                ++   ++  + L +++LC    TF +VFTV  +  ++ R+  E G   L IG++ + GV  G   SG SMNPA SL   + T   +    + +GP++G  LA +  + +F  + S   + + L   D +  +T S
Sbjct:    5 EDLRSRKFWCAILAELLGTLVLVSAVLGASVPGPEEAAVGPMYPAVAVGVAIIALSHCFGEISGAQVNPSLTLSLLATRRLDVLRALVYIAAQCFGACLAAWFLYLALPFKT-TAEHFV--------------NRVPIELNAAQALGIEVLC----TFQMVFTVYSVEDQRRRDSPEPG--NLAIGVAHSAGVLIGARFSGASMNPARSLGPAIVTGFWENHWIYWIGPVMGALLAGVSHEFLFARSASRQKLVACLTCKDIEIVETTS 252
[Close]
BLAST of Aquaporin vs. Ensembl Medaka
Match: AQP4 (aquaporin 4 [Source:NCBI gene;Acc:101164753])

HSP 1 Score: 111.694 bits (278), Expect = 1.896e-27
Identity = 91/325 (28.00%), Postives = 150/325 (46.15%), Query Frame = 1 
Query:   19 QFNSDVNI*YYKM---NQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS----NMNP-----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTN---------DIQLDKIE 930
            Q NS     + K     +  +  +FK + +   W+++  E L + +   +G GS  +       P     V + L FGL+   ++ C G ISGGHINPAV+  +++ R++SL + + Y+  Q LGA  G   + ++T          ++  S  +TK N+       N+     L   +L EL+ITF LVFT+   C   S+     G   L IG+++ +G   G+  +G SMNPA S    + T   +    + +GP+LGG LAA   + ++  +  I      +F        T SG  K++E  +         +I L+K E
Sbjct:    1 QVNSSQQCSWEKCCTCQEPNIMVAFKGIWTKEFWRAVSGEYLASVIFVLLGLGSTINWAAGEEKPPPADLVLISLCFGLSIATMVQCFGHISGGHINPAVTAAMVVTRKLSLAKALFYVAAQCLGAITGAGILYLVTPD--------TVRGSLGVTKVNT-------NV----ALGNALLVELLITFELVFTIFATC--DSKRTDLSGSPSLAIGLAVAIGHLFGIPYTGASMNPARSFGPAVVTLNFENHWVYWLGPILGGLLAAGFYEYLYCPDPEIKKRMQQIF------KKTPSGTYKEVETEDLGVKSVSGHNIDLEKAE 298
[Close]
BLAST of Aquaporin vs. Ensembl Medaka
Match: AQP4 (aquaporin 4 [Source:NCBI gene;Acc:101164753])

HSP 1 Score: 111.694 bits (278), Expect = 2.083e-27
Identity = 87/302 (28.81%), Postives = 143/302 (47.35%), Query Frame = 1 
Query:   79 SFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFS----NMNP-----VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTN---------DIQLDKIE 930
            +FK + +   W+++  E L + +   +G GS  +       P     V + L FGL+   ++ C G ISGGHINPAV+  +++ R++SL + + Y+  Q LGA  G   + ++T          ++  S  +TK N+       N+     L   +L EL+ITF LVFT+   C   S+     G   L IG+++ +G   G+  +G SMNPA S    + T   +    + +GP+LGG LAA   + ++  +  I      +F        T SG  K++E  +         +I L+K E
Sbjct:   36 AFKGIWTKEFWRAVSGEYLASVIFVLLGLGSTINWAAGEEKPPPADLVLISLCFGLSIATMVQCFGHISGGHINPAVTAAMVVTRKLSLAKALFYVAAQCLGAITGAGILYLVTPD--------TVRGSLGVTKVNT-------NV----ALGNALLVELLITFELVFTIFATC--DSKRTDLSGSPSLAIGLAVAIGHLFGIPYTGASMNPARSFGPAVVTLNFENHWVYWLGPILGGLLAAGFYEYLYCPDPEIKKRMQQIFK------KTPSGTYKEVETEDLGVKSVSGHNIDLEKAE 310
[Close]
BLAST of Aquaporin vs. Ensembl Medaka
Match: aqp1a.1 (aquaporin 1 (Colton blood group) [Source:NCBI gene;Acc:101155722])

HSP 1 Score: 103.99 bits (258), Expect = 3.987e-25
Identity = 80/278 (28.78%), Postives = 128/278 (46.04%), Query Frame = 1 
Query:   82 FKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMN------PVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVL--NPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVK-SFLFSHDFDSHDTNSGDSK 888
             ++ KS + W++++AEL+G     F+   +   N N       VKV L FGLA   +   +G ISG H+NPAV+ G+L + QIS+ + ++YI  Q+LG        S L  G V    PS+ S L  N+L     +                 +  EL+ TF LV  V+ +  ++ R+    G APL IG+S+ +G    ++ +G  +NPA S    +          + VGP+ GG  AA++   + +        +   L S     +D N G+  
Sbjct:    1 MREFKSKDFWRAVLAELVGMAFFIFLSISAAIGNSNNANPDQEVKVSLTFGLAIATLAQSLGHISGAHLNPAVTLGMLASCQISVFKAVMYIVAQMLG--------SALASGIVYGTRPSNTSALGLNSLNGVTPSQ---------------GVGIELLATFQLVLCVIAVTDKRRRD--VMGSAPLAIGLSVCLGHLAAISYTGCGINPARSFGPALILNDFTDHWVYWVGPMCGGVAAALVYDFLLSPKFDDFPDRMKVLVSGPVGDYDVNGGNES 253
[Close]
BLAST of Aquaporin vs. Ensembl Medaka
Match: mipb (lens fiber major intrinsic protein [Source:NCBI gene;Acc:101156250])

HSP 1 Score: 103.219 bits (256), Expect = 6.266e-25
Identity = 80/237 (33.76%), Postives = 111/237 (46.84%), Query Frame = 1 
Query:   88 DLKSLNLWQSIIAELLGTFLLAFIGFGSVFS-NMNP---VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAIL 786
            + +S+N W+++ AE  GT    F G G+       P   + V L FGLA   +I  IG ISGGHINPAV+F  L+  Q+SL R + YI  Q +GA  G   +  +T G +               + N A   +   I     L +    E+ +T  LV  V    V   R     G A L IG S+T+G   GM  +G  MNPA S A  +  +       + VGP++GG L A+L
Sbjct:    3 EFRSMNFWRAVFAEFFGTMFFVFFGMGAALRWTTGPHHVLHVALCFGLAAATLIQSIGHISGGHINPAVTFAYLVGSQMSLFRAVFYIAAQCMGAVAGAAVLYGVTPGNM---------------RGNMAMNMLQPGI----SLGMATTVEVFLTMQLVICV--FAVTDERRNGRLGSAALSIGFSVTIGHLMGMYYTGAGMNPARSFAPAVIFRNFINHWVYWVGPMIGGALGALL 218
[Close]
BLAST of Aquaporin vs. Planmine SMEST
Match: SMESG000023353.1 (SMESG000023353.1)

HSP 1 Score: 582.408 bits (1500), Expect = 0.000e+0
Identity = 292/292 (100.00%), Postives = 292/292 (100.00%), Query Frame = 1 
Query:   55 MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKIE 930
            MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKIE
Sbjct:    1 MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKIE 292
[Close]
BLAST of Aquaporin vs. Planmine SMEST
Match: SMESG000023352.1 (SMESG000023352.1)

HSP 1 Score: 310.457 bits (794), Expect = 1.988e-104
Identity = 161/284 (56.69%), Postives = 206/284 (72.54%), Query Frame = 1 
Query:   55 MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTN 906
            M  +RL SS +DLKS   W S++AE LGTFLL FIGFG+ ++NMNPVK+GLGFG AG+V+IYCIGPISGGHINPAVSFGLLIAR+ISL +FI++  +QILGA+ G+  I  ++   VL+ S      SN          +I E I ++++   KILCE+VITFVLVFTVMRLCVEK+R  TEKGLAPL+IG++I VGV+CGMNISGGSMNPA SL K+     S  + +HI+GPL GG +A +L QL+FTS +S  H++S+LF  DF S  + S D  + +N  
Sbjct:    1 METLRLGSSARDLKSCQFWLSVVAEFLGTFLLVFIGFGTAYNNMNPVKLGLGFGFAGIVVIYCIGPISGGHINPAVSFGLLIAREISLAKFIIFSIIQILGASAGFGMIYGVSGKGVLHKSFLRFNISNT-------SIRIDEVIHRVENPAFKILCEMVITFVLVFTVMRLCVEKTRTSTEKGLAPLVIGLAIAVGVFCGMNISGGSMNPAASLGKYFYAG-STTIWTHIIGPLSGGAIAGLLYQLMFTSQISRSHIRSYLFDSDFVSFPS-SVDYSQPKNEE 275
[Close]
BLAST of Aquaporin vs. Planmine SMEST
Match: SMESG000023346.1 (SMESG000023346.1)

HSP 1 Score: 239.965 bits (611), Expect = 2.402e-76
Identity = 137/295 (46.44%), Postives = 178/295 (60.34%), Query Frame = 1 
Query:   55 MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNS--------GDSKKMENTNDIQ 915
            + Q+R+ SS +D+   + W ++ AE LGTF+L FIG G+ + N + +KV L FGL G + IY   P+SGGHINPAVS GLL+ARQIS +R ILYI  QI+GA      IS++T  +  N +H     S+    ++ A Y                 CE++I+FVLVFTVMR+CVEKSR+  EKGLA L+IGISITVGV CG NISGGSMNPA SL   +     K +  +IVGPL+GG LA ++QQL FTS LS  H+  FL +  F                + KKMEN    +
Sbjct:   10 VKQLRIWSSLQDVTKTSFWTALFAEFLGTFILVFIGLGACYENGDVLKVALAFGLGGAIGIYISAPLSGGHINPAVSVGLLVARQISFVRCILYILFQIIGALLAAKSISLMTY-ETYNKTHGI---SHAHAPWDKALY-----------------CEIIISFVLVFTVMRMCVEKSRSEVEKGLAALLIGISITVGVLCGANISGGSMNPARSLGPAIVHSNMKLIWIYIVGPLIGGILAGLVQQLFFTSELSREHIYDFLVNPKFQMEKEFEEYEERKKFEEFKKMENRKKYE 283
[Close]
BLAST of Aquaporin vs. Planmine SMEST
Match: SMESG000028474.1 (SMESG000028474.1)

HSP 1 Score: 94.7449 bits (234), Expect = 5.156e-22
Identity = 75/275 (27.27%), Postives = 124/275 (45.09%), Query Frame = 1 
Query:   85 KDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITE-NIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYC----GMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSKKM 894
             ++K+  L+  I  E LGTF L FIG  S+ ++      G  FGL  V +I       G H+NPA+S    I+ +I  IRFI Y+  Q  G+  G + I++LT                     +S D  + E NI   +     ++ E ++TF+LV  +  +      N   +    L++G+++ V V+      M ISG SMNPA S    +   ++  +  + VGP+LG     +    +F  N+SI  +K +  +  +   D    D + +
Sbjct:    9 NEIKNPVLYVDIFVEFLGTFFLLFIGSSSLMNSNASFNAGSTFGLILVGLITVFSERGGCHLNPAISIAHFISHRIQFIRFIFYVIAQHCGSISGTILINVLTN--------------------HSFDNTVNEPNIANSR----AVVIEGILTFILVLIIFTV----KNNFNSEIYNGLLLGVAVGVTVFVFHIGFMGISGASMNPARSFGPAIYYSKTNHIWIYYVGPILGSVAGTLFYDTIFERNISIKKLKEYFTNRKYPKSDNKVVDVENI 255
[Close]
BLAST of Aquaporin vs. Planmine SMEST
Match: SMESG000067985.1 (SMESG000067985.1)

HSP 1 Score: 60.4622 bits (145), Expect = 5.646e-10
Identity = 68/282 (24.11%), Postives = 116/282 (41.13%), Query Frame = 1 
Query:  115 SIIAELLGTFLLAFIGFGSVF----SNMNP---VKVGLGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQILGATFGYLFISILTKGKVL------NPSHFSILSSNNLTKFNSADYKITENIDKIKDLHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYCGMNISGGSMNPAVSLAK----FMCTKQSKGLIS-------HIVGPLLGGFLAAILQQLVFTSNLSILHVKSFLFSHDFDSHDTNSGDSK 888
            +++ EL GTF+L   G G +     SN      + + LG+G A ++ ++  G +  GH NPAV+       ++  IR   Y   Q++GA  G L + ++   K+L      +   F + S+      + +   +T   D+     L   C + IT            ++        L P+++G+ ++  V C    +G ++NPA  L       MC    +   +        IV PLLGG   A+  ++    +   LH KS        S   NS +SK
Sbjct:   21 AMLGELWGTFILIVFGLGVILQVELSNNQYGSFLSISLGWGFAVMLAVFWSGKLGHGHTNPAVTLAFASIGRLEWIRVPFYWLAQVVGAFLGSLVLFLIYYEKILDFAANKDDGKFIVQSTGAFFITSRSTSLLTAFFDQFFGTFLLASCAIAIT------------DEDGFDLPDYLHPIMLGLMVSGIVGCFAMNAGAALNPARDLGPRIMIAMCGWGREAFTNLDFYFWVPIVAPLLGGVFGALFYEVFIGVH---LHAKS------KKSMSNNSANSK 281
The following BLAST results are available for this feature:
BLAST of Aquaporin vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AQP12.228e-2630.42aquaporin 1 (Colton blood group) [Source:HGNC Symb... [more]
AQP12.228e-2630.42aquaporin 1 (Colton blood group) [Source:HGNC Symb... [more]
AQP41.070e-2527.49aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637][more]
AQP41.070e-2527.49aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637][more]
AQP41.919e-2527.49aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637][more]
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BLAST of Aquaporin vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
aqp-66.100e-2127.92AQuaPorin or aquaglyceroporin related [Source:Uni... [more]
aqp-61.094e-2027.92AQuaPorin or aquaglyceroporin related [Source:Uni... [more]
aqp-61.619e-2027.92AQuaPorin or aquaglyceroporin related [Source:Uni... [more]
aqp-41.924e-1426.27AQuaPorin or aquaglyceroporin related [Source:Uni... [more]
aqp-25.840e-1428.85AQuaPorin or aquaglyceroporin related [Source:Uni... [more]
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BLAST of Aquaporin vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Drip1.225e-2932.40gene:FBgn0015872 transcript:FBtr0331389[more]
Drip1.441e-2932.40gene:FBgn0015872 transcript:FBtr0088141[more]
Drip1.441e-2932.40gene:FBgn0015872 transcript:FBtr0088142[more]
Drip1.687e-2932.40gene:FBgn0015872 transcript:FBtr0331387[more]
Drip1.699e-2932.40gene:FBgn0015872 transcript:FBtr0331388[more]
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BLAST of Aquaporin vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
aqp1a.18.575e-2731.28aquaporin 1a (Colton blood group), tandem duplicat... [more]
aqp41.613e-2631.50aquaporin 4 [Source:ZFIN;Acc:ZDB-GENE-040724-152][more]
aqp42.258e-2631.50aquaporin 4 [Source:ZFIN;Acc:ZDB-GENE-040724-152][more]
CR450824.23.446e-2627.68aquaporin-4-like [Source:NCBI gene;Acc:101885864][more]
mipa2.239e-2432.91major intrinsic protein of lens fiber a [Source:ZF... [more]
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BLAST of Aquaporin vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ppil21.518e-2629.25peptidylprolyl isomerase like 2 [Source:Xenbase;Ac... [more]
ENSXETT00000039945.13.863e-2530.04aquaporin-4-like [Source:NCBI gene;Acc:100487834][more]
ENSXETT00000039957.14.482e-2529.64aquaporin-4-like [Source:NCBI gene;Acc:100487834][more]
ENSXETT00000055415.17.694e-2528.36aquaporin AQPAe.a-like [Source:NCBI gene;Acc:10173... [more]
aqp53.060e-2433.33aquaporin 5 [Source:NCBI gene;Acc:100491662][more]
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BLAST of Aquaporin vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Aqp48.861e-2828.87aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387][more]
Aqp48.861e-2828.87aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387][more]
Aqp48.861e-2828.87aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387][more]
Aqp48.861e-2828.87aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387][more]
Aqp48.861e-2828.87aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387][more]
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BLAST of Aquaporin vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|G5CTG2|AQP5_MILTA2.696e-3434.90Aquaporin-5 OS=Milnesium tardigradum OX=46460 GN=A... [more]
sp|Q9V5Z7|AQP_DROME1.445e-2832.40Aquaporin OS=Drosophila melanogaster OX=7227 GN=Dr... [more]
sp|Q7PWV1|AQP_ANOGA2.102e-2732.08Aquaporin AQPAn.G OS=Anopheles gambiae OX=7165 GN=... [more]
sp|Q9NHW7|AQP_AEDAE3.384e-2733.61Aquaporin AQPAe.a OS=Aedes aegypti OX=7159 GN=AAEL... [more]
sp|P55088|AQP4_MOUSE8.960e-2728.87Aquaporin-4 OS=Mus musculus OX=10090 GN=Aqp4 PE=1 ... [more]
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BLAST of Aquaporin vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A0G4DCR14.726e-11159.36Aquaporin OS=Dugesia japonica OX=6161 GN=aquaporin... [more]
A0A0G4DC261.032e-6547.15Aquaporin OS=Dugesia japonica OX=6161 PE=2 SV=1[more]
A0A0G4DCJ98.583e-6370.47Aquaporin OS=Dugesia japonica OX=6161 GN=aquaporin... [more]
A0A0B7ASU01.743e-3635.42Uncharacterized protein OS=Arion vulgaris OX=10286... [more]
A0A2T7NJV94.892e-3635.77Uncharacterized protein OS=Pomacea canaliculata OX... [more]
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BLAST of Aquaporin vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
AQP41.643e-2930.66aquaporin-4 [Source:NCBI gene;Acc:103027636][more]
AQP42.007e-2930.66aquaporin-4 [Source:NCBI gene;Acc:103027636][more]
aqp1a.13.086e-2729.37aquaporin FA-CHIP [Source:NCBI gene;Acc:103038005][more]
aqp1a.21.175e-2632.22aquaporin-1-like [Source:NCBI gene;Acc:103041890][more]
ENSAMXT00000043631.15.842e-2626.85aquaporin-4-like [Source:NCBI gene;Acc:103025508][more]
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BLAST of Aquaporin vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
ENSPMAT00000004947.16.736e-1841.30pep scaffold:Pmarinus_7.0:GL478425:219996:222130:-... [more]
aqp3b1.043e-1226.61aquaporin 3b [Source:ZFIN;Acc:ZDB-GENE-040724-66][more]
aqp8a.11.557e-930.65aquaporin 8a, tandem duplicate 1 [Source:ZFIN;Acc:... [more]
AQP46.865e-725.74aquaporin 4 [Source:HGNC Symbol;Acc:HGNC:637][more]
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BLAST of Aquaporin vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 2
Match NameE-valueIdentityDescription
AQY11.438e-925.61Spore-specific water channel; mediates the transpo... [more]
AQY33.076e-835.24Putative channel-like protein; similar to Fps1p; m... [more]
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BLAST of Aquaporin vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 5
Match NameE-valueIdentityDescription
EDO411644.218e-1728.46Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO283617.559e-1330.45Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411242.142e-1133.64Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO450279.677e-926.61Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO411492.122e-725.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Aquaporin vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ENSORLT00000043818.12.099e-2828.62aquaporin-4 [Source:NCBI gene;Acc:101156496][more]
AQP41.896e-2728.00aquaporin 4 [Source:NCBI gene;Acc:101164753][more]
AQP42.083e-2728.81aquaporin 4 [Source:NCBI gene;Acc:101164753][more]
aqp1a.13.987e-2528.78aquaporin 1 (Colton blood group) [Source:NCBI gene... [more]
mipb6.266e-2533.76lens fiber major intrinsic protein [Source:NCBI ge... [more]
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BLAST of Aquaporin vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000023353.10.000e+0100.00SMESG000023353.1[more]
SMESG000023352.11.988e-10456.69SMESG000023352.1[more]
SMESG000023346.12.402e-7646.44SMESG000023346.1[more]
SMESG000028474.15.156e-2227.27SMESG000028474.1[more]
SMESG000067985.15.646e-1024.11SMESG000067985.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035058 ID=SMED30035058|Name=Aquaporin|organism=Schmidtea mediterranea sexual|type=transcript|length=1212bp
TAGGATCGTATAAATACCCAGTTCAATTCTGATGTCAATATTTGATATTA
TAAAATGAATCAGATCAGACTGGCAAGCAGTTTCAAAGATCTAAAGTCAC
TTAATCTTTGGCAATCGATAATTGCAGAACTTCTTGGCACCTTTCTGTTA
GCGTTTATTGGATTTGGATCCGTATTCAGCAACATGAATCCAGTGAAAGT
TGGATTGGGTTTCGGGTTGGCGGGGGTGGTTATTATCTATTGTATCGGTC
CGATAAGCGGAGGGCATATAAACCCAGCCGTAAGCTTCGGTTTACTTATT
GCAAGGCAAATTAGTTTAATACGATTCATTCTCTATATTTTTGTACAAAT
TCTTGGAGCAACATTTGGTTATTTATTTATTTCCATTTTAACGAAAGGAA
AAGTGTTGAATCCATCTCACTTTTCCATACTTAGTTCAAACAATTTAACT
AAATTTAACTCGGCTGATTATAAAATTACGGAAAACATTGATAAGATCAA
AGATTTGCATTTGAAAATCCTATGTGAGCTCGTAATTACTTTTGTTTTAG
TGTTTACAGTTATGAGACTTTGTGTGGAAAAATCAAGAAATCCAACGGAA
AAAGGTTTGGCTCCTTTAATTATTGGTATCAGTATAACAGTTGGTGTTTA
TTGTGGAATGAACATTAGCGGCGGCTCTATGAACCCAGCAGTGAGTTTGG
CAAAGTTTATGTGTACAAAACAAAGCAAAGGACTAATATCCCATATTGTT
GGTCCTTTACTTGGTGGATTTCTGGCAGCAATTCTTCAACAGCTTGTGTT
TACTTCCAACCTTTCAATTTTGCACGTGAAATCCTTTTTATTCAGCCATG
ATTTCGATAGCCATGATACCAATAGTGGGGATTCTAAAAAAATGGAAAAT
ACGAATGATATACAATTAGATAAAATAGAATAATAATGACAGTGAATCAG
ACAATTCTAAAGCCTACCAATATTCTCCTTGAAAATATTTATCTTACCTA
TTTTTATATTATATCAAATAAATGATTATCATATTATTTCATAATAATTA
TATTTATTAAATATTAGAATAGTATTCCGAACTCGGTTAACCAACTGATC
ATTGGAAATTATCCTGTTGGTATTTGAATAATTGTAAATTCTCCAAACCA
TATTTTATTTATTTTATTTATGTTAATTTTCAATTAAAAAATGTTTTCTA
ATTAAAACAAAT
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protein sequence of SMED30035058-orf-1

>SMED30035058-orf-1 ID=SMED30035058-orf-1|Name=SMED30035058-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=293bp
MNQIRLASSFKDLKSLNLWQSIIAELLGTFLLAFIGFGSVFSNMNPVKVG
LGFGLAGVVIIYCIGPISGGHINPAVSFGLLIARQISLIRFILYIFVQIL
GATFGYLFISILTKGKVLNPSHFSILSSNNLTKFNSADYKITENIDKIKD
LHLKILCELVITFVLVFTVMRLCVEKSRNPTEKGLAPLIIGISITVGVYC
GMNISGGSMNPAVSLAKFMCTKQSKGLISHIVGPLLGGFLAAILQQLVFT
SNLSILHVKSFLFSHDFDSHDTNSGDSKKMENTNDIQLDKIE*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: molecular function
TermDefinition
GO:0015267channel activity
GO:0005215transporter activity
Vocabulary: biological process
TermDefinition
GO:0055085transmembrane transport
GO:0006810transport
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0002142parenchyma
PLANA:0003116parenchymal cell
Vocabulary: INTERPRO
TermDefinition
IPR034294Aquaporin_transptr
IPR000425MIP
IPR023271Aquaporin-like
IPR022357MIP_CS
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000425Major intrinsic proteinPRINTSPR00783MINTRINSICPcoord: 53..77
score: 50.75
coord: 157..175
score: 36.49
coord: 228..248
score: 34.42
coord: 20..39
score: 39.7
coord: 90..109
score: 33.99
coord: 191..213
score: 30.82
IPR000425Major intrinsic proteinPFAMPF00230MIPcoord: 13..243
e-value: 3.0E-42
score: 144.9
IPR023271Aquaporin-likeGENE3DG3DSA:1.20.1080.10coord: 10..261
e-value: 1.3E-57
score: 196.8
IPR023271Aquaporin-likeSUPERFAMILYSSF81338Aquaporin-likecoord: 13..254
IPR034294Aquaporin transporterPANTHERPTHR19139AQUAPORIN TRANSPORTERcoord: 11..280
IPR022357Major intrinsic protein, conserved sitePROSITEPS00221MIPcoord: 71..79
NoneNo IPR availableTMHMMTMhelixcoord: 49..71
NoneNo IPR availableTMHMMTMhelixcoord: 184..206
NoneNo IPR availableTMHMMTMhelixcoord: 155..174
NoneNo IPR availableTMHMMTMhelixcoord: 86..108
NoneNo IPR availableTMHMMTMhelixcoord: 227..249
NoneNo IPR availableTMHMMTMhelixcoord: 20..42