SMED30035001

Overview
NameSMED30035001
Smed IDSMED30035001
Length (bp)469
Neoblast Clusters

Zeng et. al., 2018



 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30035001

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 6

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
tail regionSMED30035001SMESG000050245.1 SMESG000050244.1 SmedASXL_066692SmedAsxl_ww_GCZZ01PMID:27034770
Currie et al., 2016		whole organism asexual adult RNA-sequencing evidence
protonephridiaSMED30035001SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30035001SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30035001SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
cephalic gangliaSMED30035001SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
non-ciliated neuronSMED30035001SMESG000050245.1 SMESG000050244.1 dd_Smed_v4_6151_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Alignments
SMED30035001 aligns in the following genomic locations:
Alignment LocationAlignment Score
v31.012855:12775..14459 -2244
Homology
[Close]
BLAST of SMED30035001 vs. Ensembl Human
Match: CNFN (cornifelin [Source:HGNC Symbol;Acc:HGNC:30183])

HSP 1 Score: 62.7734 bits (151), Expect = 6.417e-13
Identity = 33/96 (34.38%), Postives = 49/96 (51.04%), Query Frame = -2 
Query:  103 RTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 390
            +T   +W +GL DCC+D   C+   F P C  C +   + E  C P + P     +RT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:   18 QTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSIRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 112
[Close]
BLAST of SMED30035001 vs. Ensembl Human
Match: CNFN (cornifelin [Source:HGNC Symbol;Acc:HGNC:30183])

HSP 1 Score: 62.7734 bits (151), Expect = 6.417e-13
Identity = 33/96 (34.38%), Postives = 49/96 (51.04%), Query Frame = -2 
Query:  103 RTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 390
            +T   +W +GL DCC+D   C+   F P C  C +   + E  C P + P     +RT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:   18 QTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSIRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 112
[Close]
BLAST of SMED30035001 vs. Ensembl Human
Match: PLAC8L1 (PLAC8 like 1 [Source:HGNC Symbol;Acc:HGNC:31746])

HSP 1 Score: 61.2326 bits (147), Expect = 9.696e-12
Identity = 38/118 (32.20%), Postives = 55/118 (46.61%), Query Frame = -2 
Query:  112 TTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 465
             + ++ QP         IT   Q    T   WS+GLF  C D   C    FCP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  D    + C+  ++CQ+ R++ 
Sbjct:   45 ASAVVKQPVRGASGRTTITAIVQ----TGGGWSTGLFSVCRDRRICFCGLFCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHKIQGTLCEDWLAVHCCWAFSICQVARELK 157
[Close]
BLAST of SMED30035001 vs. Ensembl Human
Match: PLAC8 (placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254])

HSP 1 Score: 55.0694 bits (131), Expect = 6.442e-10
Identity = 39/117 (33.33%), Postives = 57/117 (48.72%), Query Frame = -2 
Query:  112 VIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEF-VCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 459
            V++TQPG    V P    Q+        NW +G+ DC  DC  C+   FC  C  C +     E  +C       +++ +RT +R+R  I GSI  D   T  C  C +CQ+KRD++
Sbjct:    8 VVVTQPG----VGPGPAPQNS-------NWQTGMCDCFSDCGVCLCGTFCFPCLGCQVAADMNECCLC------GTSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDIN 107
[Close]
BLAST of SMED30035001 vs. Ensembl Human
Match: PLAC8 (placenta associated 8 [Source:HGNC Symbol;Acc:HGNC:19254])

HSP 1 Score: 55.0694 bits (131), Expect = 6.442e-10
Identity = 39/117 (33.33%), Postives = 57/117 (48.72%), Query Frame = -2 
Query:  112 VIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEF-VCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 459
            V++TQPG    V P    Q+        NW +G+ DC  DC  C+   FC  C  C +     E  +C       +++ +RT +R+R  I GSI  D   T  C  C +CQ+KRD++
Sbjct:    8 VVVTQPG----VGPGPAPQNS-------NWQTGMCDCFSDCGVCLCGTFCFPCLGCQVAADMNECCLC------GTSVAMRTLYRTRYGIPGSICDDYMATLCCPHCTLCQIKRDIN 107
[Close]
BLAST of SMED30035001 vs. Ensembl Zebrafish
Match: ponzr5 (plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB-GENE-081104-325])

HSP 1 Score: 72.4034 bits (176), Expect = 1.235e-16
Identity = 40/101 (39.60%), Postives = 53/101 (52.48%), Query Frame = -2 
Query:   97 TYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL-----FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDK 384
            T   WSSG+ DCCD+   C    +C  C+ C     + E +C PL     F PA TL +R   RSR  IKGSI  DC  + +C  C+ CQ+ R+M+  E  
Sbjct:   17 TNDQWSSGICDCCDNVPECCFSFWCFPCFACSTARKHGECLCLPLLDGFGFIPAITLAMRVSVRSRYGIKGSICKDCAYSTFCGACSWCQISREMNIREQS 117
[Close]
BLAST of SMED30035001 vs. Ensembl Zebrafish
Match: ponzr5 (plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB-GENE-081104-325])

HSP 1 Score: 72.0182 bits (175), Expect = 1.291e-16
Identity = 40/101 (39.60%), Postives = 53/101 (52.48%), Query Frame = -2 
Query:   97 TYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL-----FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDK 384
            T   WSSG+ DCCD+   C    +C  C+ C     + E +C PL     F PA TL +R   RSR  IKGSI  DC  + +C  C+ CQ+ R+M+  E  
Sbjct:   14 TNDQWSSGICDCCDNVPECCFSFWCFPCFACSTARKHGECLCLPLLDGFGFIPAITLAMRVSVRSRYGIKGSICKDCAYSTFCGACSWCQISREMNIREQS 114
[Close]
BLAST of SMED30035001 vs. Ensembl Zebrafish
Match: plac8l1 (PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165])

HSP 1 Score: 67.3958 bits (163), Expect = 1.687e-14
Identity = 34/87 (39.08%), Postives = 49/87 (56.32%), Query Frame = -2 
Query:  115 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 375
            +WS+GLFD C D ++ ++  F P C    + H Y E +C PL  P ST  +R   R R  I+G++  D    Y CY  A+CQ+ R+M
Sbjct:   45 DWSTGLFDVCGDASTLLMGTFVPCCLDLSLAHQYGECMCLPLL-PGSTFAMRVGIRERFKIRGNVCEDWMTVYCCYPLALCQMIREM 130
[Close]
BLAST of SMED30035001 vs. Ensembl Zebrafish
Match: plac8l1 (PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165])

HSP 1 Score: 66.6254 bits (161), Expect = 3.320e-14
Identity = 41/114 (35.96%), Postives = 58/114 (50.88%), Query Frame = -2 
Query:  115 IITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 456
            ++TQPG       V T        T  +WS+GLFD C D ++ ++  F P C    + H Y E +C PL  P ST  +R   R R  I+G++  D    Y CY  A+CQ+ R+M
Sbjct:   28 VLTQPGLGETTTTVTTVT-----QTGGDWSTGLFDVCGDASTLLMGTFVPCCLDLSLAHQYGECMCLPLL-PGSTFAMRVGIRERFKIRGNVCEDWMTVYCCYPLALCQMIREM 135
[Close]
BLAST of SMED30035001 vs. Ensembl Zebrafish
Match: ponzr2 (plac8 onzin related protein 2 [Source:ZFIN;Acc:ZDB-GENE-050411-41])

HSP 1 Score: 62.3882 bits (150), Expect = 7.758e-13
Identity = 34/94 (36.17%), Postives = 47/94 (50.00%), Query Frame = -2 
Query:  115 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLF-------TPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 375
            +W S + DCCDD   C    +C  CY C     Y E +C PL         P  T+ +RT  R R  I+G++  DC L+ +C  C  CQ+ R+M
Sbjct:   21 HWGSDICDCCDDVPECCFAFWCFSCYTCIQARNYGECLCLPLLDIFCGGMIPPITMSIRTSMRQRYGIQGTMCNDCVLSTFCRPCVWCQMSREM 114
[Close]
BLAST of SMED30035001 vs. Ensembl Xenopus
Match: ifi35 (interferon induced protein 35 [Source:Xenbase;Acc:XB-GENE-1010748])

HSP 1 Score: 65.0846 bits (157), Expect = 9.991e-14
Identity = 35/92 (38.04%), Postives = 49/92 (53.26%), Query Frame = -2 
Query:  112 TTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 387
            + +  W+S  FDC  D   C+  AF P C  C +   Y E  C PL    + L LRT  R R HI+G+I  DC    +C  CA+CQ+ R+++
Sbjct:   33 SKFGQWNSDTFDCFRDVGICLCGAFFPMCVACKVAQDYGECCCLPLM-GGTILALRTGIRERYHIQGTICTDCLCVTFCGPCALCQMARELE 123
[Close]
BLAST of SMED30035001 vs. Ensembl Xenopus
Match: ENSXETT00000008293.1 (novel protein similar to cornifelin [Source:NCBI gene;Acc:733751])

HSP 1 Score: 64.6994 bits (156), Expect = 1.187e-13
Identity = 35/92 (38.04%), Postives = 49/92 (53.26%), Query Frame = -2 
Query:  112 TTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 387
            + +  W+S  FDC  D   C+  AF P C  C +   Y E  C PL    + L LRT  R R HI+G+I  DC    +C  CA+CQ+ R+++
Sbjct:   23 SKFGQWNSDTFDCFRDVGICLCGAFFPMCVACKVAQDYGECCCLPLM-GGTILALRTGIRERYHIQGTICTDCLCVTFCGPCALCQMARELE 113
[Close]
BLAST of SMED30035001 vs. Ensembl Xenopus
Match: ifi35 (interferon induced protein 35 [Source:Xenbase;Acc:XB-GENE-1010748])

HSP 1 Score: 64.6994 bits (156), Expect = 1.219e-13
Identity = 35/92 (38.04%), Postives = 49/92 (53.26%), Query Frame = -2 
Query:  112 TTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 387
            + +  W+S  FDC  D   C+  AF P C  C +   Y E  C PL    + L LRT  R R HI+G+I  DC    +C  CA+CQ+ R+++
Sbjct:   31 SKFGQWNSDTFDCFRDVGICLCGAFFPMCVACKVAQDYGECCCLPLMG-GTILALRTGIRERYHIQGTICTDCLCVTFCGPCALCQMARELE 121
[Close]
BLAST of SMED30035001 vs. Ensembl Xenopus
Match: myo19 (myosin XIX [Source:Xenbase;Acc:XB-GENE-999897])

HSP 1 Score: 62.003 bits (149), Expect = 1.290e-12
Identity = 36/109 (33.03%), Postives = 55/109 (50.46%), Query Frame = -2 
Query:  112 VAPVITRQDQ-IPRTTYRN---WSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 426
            ++  I+ Q Q +P  T  N   W+S +FDCC D   C+   F P C  C +   Y E  C P+    + + +RT  R R  I G+I  DC    +C  C +CQ+ R+++
Sbjct:    1 MSQAISSQPQAVPGCTNSNTNRWNSDVFDCCQDLGICLCGTFLPLCLACKVAQDYGECCCLPVLN-GTIIAMRTGIRERYQIPGTICNDCVCLTFCGPCTLCQMARELN 108
[Close]
BLAST of SMED30035001 vs. Ensembl Xenopus
Match: abtb1 (ankyrin repeat and BTB (POZ) domain containing 1 [Source:Xenbase;Acc:XB-GENE-976579])

HSP 1 Score: 54.6842 bits (130), Expect = 6.899e-10
Identity = 33/92 (35.87%), Postives = 47/92 (51.09%), Query Frame = -2 
Query:  115 TTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTP-LFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 387
            +    W+S +FDCC+D   C+   F P    C +   + E  C P LF   S L +RT  R R HI+GSI  D     +C  C +CQ+ R++
Sbjct:   18 SNSSQWNSDVFDCCEDMGICLCGTFVPCILACKVSQDFGECCCLPCLF--GSVLAVRTGIRERYHIEGSICNDWVCLSFCGQCTLCQMAREL 107
[Close]
BLAST of SMED30035001 vs. Ensembl Mouse
Match: Cnfn (cornifelin [Source:MGI Symbol;Acc:MGI:1919633])

HSP 1 Score: 65.4698 bits (158), Expect = 4.118e-14
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = -2 
Query:  103 ITRQDQIPRTTYR----NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 414
            +T Q Q   T Y+    +W +GL DCC+D   C+   F P C  C +   + E  C P + P     LRT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 111
[Close]
BLAST of SMED30035001 vs. Ensembl Mouse
Match: Cnfn (cornifelin [Source:MGI Symbol;Acc:MGI:1919633])

HSP 1 Score: 65.4698 bits (158), Expect = 5.538e-14
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = -2 
Query:  103 ITRQDQIPRTTYR----NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 414
            +T Q Q   T Y+    +W +GL DCC+D   C+   F P C  C +   + E  C P + P     LRT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:   18 VTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 124
[Close]
BLAST of SMED30035001 vs. Ensembl Mouse
Match: Plac8l1 (PLAC8-like 1 [Source:MGI Symbol;Acc:MGI:1916651])

HSP 1 Score: 63.1586 bits (152), Expect = 1.296e-12
Identity = 33/91 (36.26%), Postives = 49/91 (53.85%), Query Frame = -2 
Query:  112 TYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 384
            T  +WS+GLF  C D   C     CP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  DC + + C+  ++CQ+ R++ 
Sbjct:   68 TGGDWSTGLFSVCRDRKICFWGLLCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHRIQGTLCEDCVVVHCCWPFSICQVARELK 157
[Close]
BLAST of SMED30035001 vs. Ensembl Mouse
Match: Plac8 (placenta-specific 8 [Source:MGI Symbol;Acc:MGI:2445289])

HSP 1 Score: 58.5362 bits (140), Expect = 1.894e-11
Identity = 41/125 (32.80%), Postives = 60/125 (48.00%), Query Frame = -2 
Query:   88 TVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGY 462
            TVI+TQPG             + P+ +  NW + L DC  DC  C+   FC  C  C +     E          +T+ +RT +R+R  I GSI  D  +T +C  C++CQLKRD++     N +
Sbjct:    6 TVIVTQPGFV-----------RAPQNS--NWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECC-----LCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMNAF 112
[Close]
BLAST of SMED30035001 vs. Ensembl Mouse
Match: Plac8 (placenta-specific 8 [Source:MGI Symbol;Acc:MGI:2445289])

HSP 1 Score: 58.5362 bits (140), Expect = 1.894e-11
Identity = 41/125 (32.80%), Postives = 60/125 (48.00%), Query Frame = -2 
Query:   88 TVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGY 462
            TVI+TQPG             + P+ +  NW + L DC  DC  C+   FC  C  C +     E          +T+ +RT +R+R  I GSI  D  +T +C  C++CQLKRD++     N +
Sbjct:    6 TVIVTQPGFV-----------RAPQNS--NWQTSLCDCFSDCGVCLCGTFCFTCLGCQVAADMNECC-----LCGTTVAMRTLYRTRYGIPGSICDDYMVTLFCPVCSVCQLKRDINRRRAMNAF 112
[Close]
BLAST of SMED30035001 vs. UniProt/SwissProt
Match: sp|Q6PCW6|CNFN_MOUSE (Cornifelin OS=Mus musculus OX=10090 GN=Cnfn PE=1 SV=1)

HSP 1 Score: 65.4698 bits (158), Expect = 2.880e-13
Identity = 38/108 (35.19%), Postives = 54/108 (50.00%), Query Frame = -2 
Query:  103 ITRQDQIPRTTYR----NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 414
            +T Q Q   T Y+    +W +GL DCC+D   C+   F P C  C +   + E  C P + P     LRT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQCANTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSLRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 111
[Close]
BLAST of SMED30035001 vs. UniProt/SwissProt
Match: sp|Q0VBW2|CNFN_BOVIN (Cornifelin OS=Bos taurus OX=9913 GN=CNFN PE=3 SV=1)

HSP 1 Score: 65.0846 bits (157), Expect = 4.141e-13
Identity = 39/108 (36.11%), Postives = 54/108 (50.00%), Query Frame = -2 
Query:  103 ITRQDQIPRTTYR----NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 414
            +T Q Q   T Y+    +W +GL DCC+D   C+   F P C  C +   + E  CTP + P     LRT  R R  I+GSI  D     +C  CA+CQ+ R++   E
Sbjct:    5 VTSQPQSASTCYQTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCTP-YLPGGLHSLRTGMRERYRIQGSIGKDWAALTFCLPCALCQMARELKIRE 111
[Close]
BLAST of SMED30035001 vs. UniProt/SwissProt
Match: sp|Q9BYD5|CNFN_HUMAN (Cornifelin OS=Homo sapiens OX=9606 GN=CNFN PE=1 SV=2)

HSP 1 Score: 62.7734 bits (151), Expect = 3.082e-12
Identity = 33/96 (34.38%), Postives = 49/96 (51.04%), Query Frame = -2 
Query:  103 RTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVE 390
            +T   +W +GL DCC+D   C+   F P C  C +   + E  C P + P     +RT  R R HI+GS+  D     +C  CA+CQ+ R++   E
Sbjct:   18 QTQLSDWHTGLTDCCNDMPVCLCGTFAPLCLACRISDDFGECCCAP-YLPGGLHSIRTGMRERYHIQGSVGHDWAALTFCLPCALCQMARELKIRE 112
[Close]
BLAST of SMED30035001 vs. UniProt/SwissProt
Match: sp|Q08EJ0|PL8L1_MOUSE (PLAC8-like protein 1 OS=Mus musculus OX=10090 GN=Plac8l1 PE=2 SV=2)

HSP 1 Score: 63.1586 bits (152), Expect = 9.067e-12
Identity = 33/91 (36.26%), Postives = 49/91 (53.85%), Query Frame = -2 
Query:  112 TYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 384
            T  +WS+GLF  C D   C     CP C  C +   Y E +C PL  P ST  LR   R R+ I+G++  DC + + C+  ++CQ+ R++ 
Sbjct:   68 TGGDWSTGLFSVCRDRKICFWGLLCPMCLECDIARHYGECLCWPLL-PGSTFALRIGTRERHRIQGTLCEDCVVVHCCWPFSICQVARELK 157
[Close]
BLAST of SMED30035001 vs. UniProt/SwissProt
Match: sp|Q3ZCB2|PLAC8_BOVIN (Placenta-specific gene 8 protein OS=Bos taurus OX=9913 GN=PLAC8 PE=3 SV=1)

HSP 1 Score: 60.8474 bits (146), Expect = 1.684e-11
Identity = 40/117 (34.19%), Postives = 59/117 (50.43%), Query Frame = -2 
Query:  112 VIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEF-VCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 459
            VI+TQPG  +  AP              NW +GL DC  DC  C+   FC  C  C +     E  +C       +++ +RT +R+R  I GSI  D  +T+ C  C++CQ+KRD++
Sbjct:    9 VIVTQPGVGSGPAP-----------QNSNWQTGLCDCFSDCGVCLCGTFCFTCLACQVASDMNECCLC------GTSVAMRTLYRTRYGIPGSICDDFMVTHCCPLCSLCQIKRDIN 108
[Close]
BLAST of SMED30035001 vs. TrEMBL
Match: A0A4S2L0X4 (Uncharacterized protein OS=Opisthorchis felineus OX=147828 GN=CRM22_010192 PE=4 SV=1)

HSP 1 Score: 110.923 bits (276), Expect = 2.081e-28
Identity = 54/114 (47.37%), Postives = 70/114 (61.40%), Query Frame = -2 
Query:   82 APVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 423
             P+I +  QIP   +R+W  GLF C +D  SC+ + FC  CY+CYMY  Y E +   L TPAS ++LRT HR R  I GS+  DC  +  C +C +CQL RDM YVE   GYL+
Sbjct:   11 GPIIIQPKQIP---FRDWHDGLFGCRNDWKSCLYVTFCTPCYICYMYERYGECLLGSLVTPASVMMLRTFHRGRERIYGSLFKDCLHSTLCPWCVLCQLDRDMKYVEATKGYLD 121
[Close]
BLAST of SMED30035001 vs. TrEMBL
Match: G7Y6C5 (Cornifelin OS=Clonorchis sinensis OX=79923 GN=CNFN PE=4 SV=1)

HSP 1 Score: 109.383 bits (272), Expect = 7.548e-28
Identity = 53/114 (46.49%), Postives = 71/114 (62.28%), Query Frame = -2 
Query:   82 APVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 423
             P+I +  QIP   +R+W  GLF C +D  SC+ ++FC  CY+C+MY  Y E +   L TPAS ++LRT HR R  I GS+  DC  +  C +C +CQL RDM YVE   GYL+
Sbjct:    7 GPIIIQPKQIP---FRDWHDGLFGCRNDWKSCLYVSFCTPCYICHMYERYGECLFGSLITPASVMMLRTFHRGRERIYGSLFKDCLHSTLCPWCVLCQLDRDMKYVEATKGYLD 117
[Close]
BLAST of SMED30035001 vs. TrEMBL
Match: A0A1S8WWB7 (Putative Cys-rich domain protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_05422 PE=4 SV=1)

HSP 1 Score: 108.612 bits (270), Expect = 1.423e-26
Identity = 51/114 (44.74%), Postives = 70/114 (61.40%), Query Frame = -2 
Query:   82 APVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 423
             P+I +  Q+P   +R+W  GL+ C +D  SC+ + FC  CY+C+MY  Y E +   L TPAS ++LRT HR R  I GS+  DC  +  C +C +CQL RDM YVE   GYL+
Sbjct:    7 GPIIIQPKQVP---FRDWHDGLYGCRNDWKSCLYVTFCTPCYICHMYERYGECLFGSLITPASIMMLRTFHRGRERIYGSLFKDCLQSILCPWCVLCQLDRDMKYVEATKGYLD 117
[Close]
BLAST of SMED30035001 vs. TrEMBL
Match: A0A074ZEK5 (Uncharacterized protein OS=Opisthorchis viverrini OX=6198 GN=T265_14156 PE=4 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 1.503e-26
Identity = 50/114 (43.86%), Postives = 70/114 (61.40%), Query Frame = -2 
Query:   82 APVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 423
             P+I +  Q+P   +R+W  GL+ C +D  +C+ + FC  CY+C+MY  Y E +   L TPAS ++LRT HR R  I GS+  DC  +  C +C +CQL RDM YVE   GYL+
Sbjct:    7 GPIIIQPKQVP---FRDWHDGLYGCRNDWKTCLYVTFCTPCYICHMYERYGECLFGSLITPASIMMLRTFHRGRERIYGSLFKDCLQSILCPWCVLCQLDRDMKYVEATKGYLD 117
[Close]
BLAST of SMED30035001 vs. TrEMBL
Match: A0A4E0RMG0 (Placenta-specific gene 8 protein OS=Fasciola hepatica OX=6192 GN=D915_001276 PE=4 SV=1)

HSP 1 Score: 105.531 bits (262), Expect = 2.965e-26
Identity = 52/114 (45.61%), Postives = 68/114 (59.65%), Query Frame = -2 
Query:   82 APVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 423
            AP+  +  QIP   +R+W  GL  C  D  SC  +  C  CY+CYM+  Y E VCTPLF P   ++LRT HR R  I GS+  DC  + +C +C++CQL RDM Y E   GYL+
Sbjct:   11 APISDQPHQIP---FRDWHDGLCQCSSDWKSCACVTLCTCCYMCYMFKRYNENVCTPLFIPTPIMMLRTYHRGRERIVGSLFRDCVTSAFCPWCSLCQLDRDMKYQEITRGYLD 121
[Close]
BLAST of SMED30035001 vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 71.633 bits (174), Expect = 3.259e-16
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = -2 
Query:  109 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 375
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKY 118
[Close]
BLAST of SMED30035001 vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 71.633 bits (174), Expect = 3.259e-16
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = -2 
Query:  109 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 375
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKY 118
[Close]
BLAST of SMED30035001 vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 71.2478 bits (173), Expect = 3.268e-16
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = -2 
Query:  109 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 375
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKY 118
[Close]
BLAST of SMED30035001 vs. Ensembl Cavefish
Match: ponzr6 (cornifelin homolog [Source:NCBI gene;Acc:103028345])

HSP 1 Score: 70.8626 bits (172), Expect = 3.667e-16
Identity = 37/96 (38.54%), Postives = 51/96 (53.12%), Query Frame = -2 
Query:  109 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL-------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 375
             WSSG+ DCC+D   C    +CP C +C     Y E +C PL         P  T  +R+  R R HI+GS+  DCC++  C  CA CQ+ R++ Y
Sbjct:   23 QWSSGICDCCEDMGICCFGFWCPYCLMCNTTKKYGECMCLPLVELCFGGLIPPVTYSMRSSMRERYHIQGSMCDDCCVSTCCGICAWCQIARELKY 118
[Close]
BLAST of SMED30035001 vs. Ensembl Cavefish
Match: ponzr2 (cornifelin homolog [Source:NCBI gene;Acc:103025611])

HSP 1 Score: 67.3958 bits (163), Expect = 1.956e-14
Identity = 35/93 (37.63%), Postives = 48/93 (51.61%), Query Frame = -2 
Query:  112 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLF-----TPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 375
             W SG+ DCCDD   C    +C  C+ C     Y + +C PL       PA+TL +R   R R  IKG++  DC +   C  CA CQ+ R+M+
Sbjct:   61 EWGSGICDCCDDVPECCFAFWCCPCFACIKTKEYGQCLCLPLLDICGIVPAATLSMRVSMRHRYGIKGTLCNDCLIATCCTSCAWCQMSREMN 153
[Close]
BLAST of SMED30035001 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000009354.1 (pep scaffold:Pmarinus_7.0:GL483774:7229:14014:-1 gene:ENSPMAG00000008464.1 transcript:ENSPMAT00000009354.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 60.4622 bits (145), Expect = 6.779e-13
Identity = 37/122 (30.33%), Postives = 58/122 (47.54%), Query Frame = -2 
Query:   94 VIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKN 459
            V++TQP     VA  +  Q Q        WSS + DC  D   CV   FC     C +   + E  C P+  P + + LRT  R R+HI+G++  D    + C  C  CQ+ R++ + +++ 
Sbjct:    5 VLVTQP-----VAHTVNVQGQA------QWSSHMMDCFQDTEICVCGFFCLPLLQCKVASDFGECFCVPML-PGALMALRTGIRERHHIEGTVFDDFVSLWCCNHCTTCQMARELRHQKNRG 114
[Close]
BLAST of SMED30035001 vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001184.1 (pep scaffold:Pmarinus_7.0:GL488356:6425:7851:-1 gene:ENSPMAG00000001063.1 transcript:ENSPMAT00000001184.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 55.0694 bits (131), Expect = 2.977e-11
Identity = 28/69 (40.58%), Postives = 40/69 (57.97%), Query Frame = -2 
Query:  109 FCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 315
            FC  C  C M   + E  C P+  P S++ LRT  R R HI+GSI  DC +  +C+ CA CQ+ R++ +
Sbjct:   16 FCMLCLNCRMAKDFGECFCLPIL-PGSSMALRTAIRERYHIQGSICDDCVMLTFCFCCATCQMAREIKH 83
[Close]
BLAST of SMED30035001 vs. Ensembl Nematostella
Match: EDO42647 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0V8])

HSP 1 Score: 57.3806 bits (137), Expect = 1.609e-11
Identity = 32/96 (33.33%), Postives = 49/96 (51.04%), Query Frame = -2 
Query:  106 RNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYH-----IYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYV 378
            R+WSSGLF+C  D   C++   CP   LC +       + Y   C  +    +   LR K R+  +I+GS+  D      C  CA+CQ+ R++D+V
Sbjct:   28 RDWSSGLFECTKDIGGCLVTFLCPCVTLCQISQRMGEGLAYGCCCADI----AAFTLRAKLRTEQNIQGSLCNDAIHVSCCMHCALCQMSRELDHV 119
[Close]
BLAST of SMED30035001 vs. Ensembl Nematostella
Match: EDO42612 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S0W1])

HSP 1 Score: 52.7582 bits (125), Expect = 1.658e-9
Identity = 33/91 (36.26%), Postives = 47/91 (51.65%), Query Frame = -2 
Query:  106 RNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYV 378
            R+W SG+  C DD  SC+L  FCP   L  +     E  C P   P + + LR K R   +I+GS+I D C       C +CQL R++ ++
Sbjct:   52 RDWHSGMCGCFDDIGSCLLGYFCPCFLLIDVSQRMGEGCCFPCCCPGALVGLRVKLRVEQNIQGSLINDYCAVQCLPLCVLCQLSRELKHL 142
[Close]
BLAST of SMED30035001 vs. Ensembl Nematostella
Match: EDO50068 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RFB0])

HSP 1 Score: 48.521 bits (114), Expect = 2.778e-8
Identity = 30/99 (30.30%), Postives = 46/99 (46.46%), Query Frame = -2 
Query:  115 RNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCT-------PLFTPASTLLL----RTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 378
             +W++GLF C +DC +C++    P    CY +    E V           F P   L++    R K R ++ I GS I DC  T  C FC++ Q  + +
Sbjct:    3 NDWNNGLFGCFNDCGTCLITYIAP----CYTFGKNAEAVGDSCLLCGLAFFVPVVDLIVMSSVRGKIREQHGISGSFIGDCAATICCPFCSLVQSAQQV 97
[Close]
BLAST of SMED30035001 vs. Ensembl Nematostella
Match: EDO44794 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RUR8])

HSP 1 Score: 46.595 bits (109), Expect = 1.501e-7
Identity = 29/99 (29.29%), Postives = 47/99 (47.47%), Query Frame = -2 
Query:  112 NWSSGLFDCCDDCTSCVLIAFCPECYL-----------CYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMD 375
            +WSSG+  C +D  +C L  FCP C +           C+++       C  +F  A    +R K R ++ I+GS   DC + ++C  CA  Q  R++ 
Sbjct:    2 SWSSGICGCFEDINTCALTYFCP-CVVAGKNAEAVGENCFLHGFLSTLGCVGIFCGAK---IREKIREKHGIEGSFGNDCIMHWFCPLCAYSQEARELK 96
[Close]
BLAST of SMED30035001 vs. Ensembl Medaka
Match: plac8l1 (PLAC8 like 1 [Source:NCBI gene;Acc:101175585])

HSP 1 Score: 70.0922 bits (170), Expect = 2.340e-15
Identity = 45/115 (39.13%), Postives = 59/115 (51.30%), Query Frame = -2 
Query:  115 VIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 459
            V++TQPG       V T        T  NWS+GLF+   D T+C+L A  P C    + H Y E +C PL  P ST  +R   R R  I+GS+  D    Y CY  A+CQ+ R+M
Sbjct:   47 VVLTQPGLG-----VTTTTITTITQTGGNWSTGLFNIWGDKTTCLLGALVPCCLDLSLAHQYGECLCLPLL-PGSTFAIRVGIRERYKIQGSVCEDWTAVYCCYPLAVCQMIREM 155
[Close]
BLAST of SMED30035001 vs. Ensembl Medaka
Match: ENSORLT00000012432.2 (cornifelin-like [Source:NCBI gene;Acc:101164880])

HSP 1 Score: 60.8474 bits (146), Expect = 6.399e-12
Identity = 32/104 (30.77%), Postives = 51/104 (49.04%), Query Frame = -2 
Query:  109 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL---------------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 375
            +W++ LFDC +D ++C    +C  C  C +   + E  C P+               F P   + +R   RSR  IKGSI AD   +Y+C  C+ CQ+ R++ +
Sbjct:    8 DWNTDLFDCFEDASTCCYGCWCGPCLACTVSGRFGERYCLPMLDISTTGSQILPIPAFVPPVAVSMRAAMRSRYGIKGSIAADIAASYYCAPCSWCQMHRELKH 111
[Close]
BLAST of SMED30035001 vs. Ensembl Medaka
Match: ENSORLT00000041395.1 (cornifelin-like [Source:NCBI gene;Acc:101164880])

HSP 1 Score: 60.8474 bits (146), Expect = 6.399e-12
Identity = 32/104 (30.77%), Postives = 51/104 (49.04%), Query Frame = -2 
Query:  109 NWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPL---------------FTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDY 375
            +W++ LFDC +D ++C    +C  C  C +   + E  C P+               F P   + +R   RSR  IKGSI AD   +Y+C  C+ CQ+ R++ +
Sbjct:    8 DWNTDLFDCFEDASTCCYGCWCGPCLACTVSGRFGERYCLPMLDISTTGSQILPIPAFVPPVAVSMRAAMRSRYGIKGSIAADIAASYYCAPCSWCQMHRELKH 111
[Close]
BLAST of SMED30035001 vs. Ensembl Medaka
Match: ponzr3 (cornifelin homolog A [Source:NCBI gene;Acc:101160195])

HSP 1 Score: 59.6918 bits (143), Expect = 6.476e-12
Identity = 34/99 (34.34%), Postives = 49/99 (49.49%), Query Frame = -2 
Query:  115 IPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLF-----TPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 396
            I  +T   WSSG+ DC DD  SC    +C  C+ C       E +C PL       P  T  +R   R +  I+G+I  DC  +++C  C+ CQ+ R+M
Sbjct:   14 ITTSTSNEWSSGICDCFDDLRSCCFAFWCFPCFACITSKKAGECLCLPLLDGFGCIPPITTAMRVSIRKQYGIEGTICRDCVFSFFCGPCSWCQISREM 112
[Close]
BLAST of SMED30035001 vs. Ensembl Medaka
Match: ENSORLT00000028572.1 (cornifelin homolog [Source:NCBI gene;Acc:101172524])

HSP 1 Score: 59.3066 bits (142), Expect = 8.304e-12
Identity = 36/115 (31.30%), Postives = 50/115 (43.48%), Query Frame = -2 
Query:  115 VIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDM 459
            V+  QPG       V T +          WS+GL  C +DC  C L  FCP    CY  H Y E  C     P     +RT  R    I+G++  D  + + C  C MC++ R++
Sbjct:    5 VVTHQPGAGGYGTNVQTGE----------WSTGLCSCFNDCLICALGFFCPAGLSCYTAHKYGENFCLGC-VPGGMTAMRTHMRLTYGIQGTVCNDAIMVFCCGLCEMCRMAREI 108
[Close]
BLAST of SMED30035001 vs. Planmine SMEST
Match: SMESG000050244.1 (SMESG000050244.1)

HSP 1 Score: 270.781 bits (691), Expect = 5.044e-95
Identity = 129/129 (100.00%), Postives = 129/129 (100.00%), Query Frame = -2 
Query:   82 MTTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 468
            MTTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE
Sbjct:    1 MTTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 129
[Close]
BLAST of SMED30035001 vs. Planmine SMEST
Match: SMESG000050244.1 (SMESG000050244.1)

HSP 1 Score: 259.225 bits (661), Expect = 1.811e-90
Identity = 126/129 (97.67%), Postives = 126/129 (97.67%), Query Frame = -2 
Query:   82 MTTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 468
            MTTVIITQPGHKNQV   ITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE
Sbjct:    1 MTTVIITQPGHKNQV---ITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 126
[Close]
BLAST of SMED30035001 vs. Planmine SMEST
Match: SMESG000050245.1 (SMESG000050245.1)

HSP 1 Score: 233.802 bits (595), Expect = 1.832e-80
Identity = 112/129 (86.82%), Postives = 115/129 (89.15%), Query Frame = -2 
Query:   82 MTTVIITQPGHKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 468
            MTTV +TQPG  NQ    ITRQ+QI   TYRNWSSGLFDCCDDC SC  + FCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE
Sbjct:    1 MTTVFVTQPGQGNQA---ITRQNQIAEPTYRNWSSGLFDCCDDCASCWCVTFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 126
[Close]
BLAST of SMED30035001 vs. Planmine SMEST
Match: SMESG000050175.1 (SMESG000050175.1)

HSP 1 Score: 145.206 bits (365), Expect = 3.216e-45
Identity = 75/130 (57.69%), Postives = 90/130 (69.23%), Query Frame = -2 
Query:   82 TVIITQPG---HKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 462
              +I QPG   + NQ   VI +Q    R   R+WSS LF CC+DCTSC L     ECYLCY+Y  + EFVCTPLFTP+S LLLRTKHR+R+ IKG+I+ D C  Y CY C MCQLKRDM+YVE+ NG L+
Sbjct:   11 NTVIIQPGVPTYGNQT--VIIQQQPNQRNLPRDWSSELFGCCEDCTSCWLSLCFAECYLCYLYSKHNEFVCTPLFTPSSLLLLRTKHRARHRIKGTIMGDACKIYCCYICTMCQLKRDMNYVEETNGSLD 138
[Close]
BLAST of SMED30035001 vs. Planmine SMEST
Match: SMESG000050177.1 (SMESG000050177.1)

HSP 1 Score: 137.117 bits (344), Expect = 4.803e-42
Identity = 71/135 (52.59%), Postives = 89/135 (65.93%), Query Frame = -2 
Query:   82 MTTVIITQPG------HKNQVAPVITRQDQIPRTTYRNWSSGLFDCCDDCTSCVLIAFCPECYLCYMYHIYYEFVCTPLFTPASTLLLRTKHRSRNHIKGSIIADCCLTYWCYFCAMCQLKRDMDYVEDKNGYLE 468
            + T ++ QPG      + NQ   +I    Q      R WSSG+  CC+DCTSC L  F   CY CY++HIY EF+CTP+    S L LRTKHR+R+ I+G+II DCC TYWCY+CA+CQLKRDMDYVED  G L+
Sbjct:    9 LPTPVLVQPGVMANPMNINQTTVII---QQPVANGPRLWSSGICGCCEDCTSCCLTMFFTHCYTCYLFHIYDEFLCTPICMYDSVLQLRTKHRARHGIRGTIIEDCCKTYWCYWCAICQLKRDMDYVEDTKGSLD 140
The following BLAST results are available for this feature:
BLAST of SMED30035001 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
CNFN6.417e-1334.38cornifelin [Source:HGNC Symbol;Acc:HGNC:30183][more]
CNFN6.417e-1334.38cornifelin [Source:HGNC Symbol;Acc:HGNC:30183][more]
PLAC8L19.696e-1232.20PLAC8 like 1 [Source:HGNC Symbol;Acc:HGNC:31746][more]
PLAC86.442e-1033.33placenta associated 8 [Source:HGNC Symbol;Acc:HGNC... [more]
PLAC86.442e-1033.33placenta associated 8 [Source:HGNC Symbol;Acc:HGNC... [more]
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BLAST of SMED30035001 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30035001 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30035001 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ponzr51.235e-1639.60plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB... [more]
ponzr51.291e-1639.60plac8 onzin related protein 5 [Source:ZFIN;Acc:ZDB... [more]
plac8l11.687e-1439.08PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165][more]
plac8l13.320e-1435.96PLAC8 like 1 [Source:ZFIN;Acc:ZDB-GENE-091204-165][more]
ponzr27.758e-1336.17plac8 onzin related protein 2 [Source:ZFIN;Acc:ZDB... [more]
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BLAST of SMED30035001 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ifi359.991e-1438.04interferon induced protein 35 [Source:Xenbase;Acc:... [more]
ENSXETT00000008293.11.187e-1338.04novel protein similar to cornifelin [Source:NCBI g... [more]
ifi351.219e-1338.04interferon induced protein 35 [Source:Xenbase;Acc:... [more]
myo191.290e-1233.03myosin XIX [Source:Xenbase;Acc:XB-GENE-999897][more]
abtb16.899e-1035.87ankyrin repeat and BTB (POZ) domain containing 1 [... [more]
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BLAST of SMED30035001 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Cnfn4.118e-1435.19cornifelin [Source:MGI Symbol;Acc:MGI:1919633][more]
Cnfn5.538e-1435.19cornifelin [Source:MGI Symbol;Acc:MGI:1919633][more]
Plac8l11.296e-1236.26PLAC8-like 1 [Source:MGI Symbol;Acc:MGI:1916651][more]
Plac81.894e-1132.80placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244... [more]
Plac81.894e-1132.80placenta-specific 8 [Source:MGI Symbol;Acc:MGI:244... [more]
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BLAST of SMED30035001 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q6PCW6|CNFN_MOUSE2.880e-1335.19Cornifelin OS=Mus musculus OX=10090 GN=Cnfn PE=1 S... [more]
sp|Q0VBW2|CNFN_BOVIN4.141e-1336.11Cornifelin OS=Bos taurus OX=9913 GN=CNFN PE=3 SV=1[more]
sp|Q9BYD5|CNFN_HUMAN3.082e-1234.38Cornifelin OS=Homo sapiens OX=9606 GN=CNFN PE=1 SV... [more]
sp|Q08EJ0|PL8L1_MOUSE9.067e-1236.26PLAC8-like protein 1 OS=Mus musculus OX=10090 GN=P... [more]
sp|Q3ZCB2|PLAC8_BOVIN1.684e-1134.19Placenta-specific gene 8 protein OS=Bos taurus OX=... [more]
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BLAST of SMED30035001 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A4S2L0X42.081e-2847.37Uncharacterized protein OS=Opisthorchis felineus O... [more]
G7Y6C57.548e-2846.49Cornifelin OS=Clonorchis sinensis OX=79923 GN=CNFN... [more]
A0A1S8WWB71.423e-2644.74Putative Cys-rich domain protein (Fragment) OS=Opi... [more]
A0A074ZEK51.503e-2643.86Uncharacterized protein OS=Opisthorchis viverrini ... [more]
A0A4E0RMG02.965e-2645.61Placenta-specific gene 8 protein OS=Fasciola hepat... [more]
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BLAST of SMED30035001 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
ponzr63.259e-1638.54cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr63.259e-1638.54cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr63.268e-1638.54cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr63.667e-1638.54cornifelin homolog [Source:NCBI gene;Acc:103028345... [more]
ponzr21.956e-1437.63cornifelin homolog [Source:NCBI gene;Acc:103025611... [more]
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BLAST of SMED30035001 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 2
Match NameE-valueIdentityDescription
ENSPMAT00000009354.16.779e-1330.33pep scaffold:Pmarinus_7.0:GL483774:7229:14014:-1 g... [more]
ENSPMAT00000001184.12.977e-1140.58pep scaffold:Pmarinus_7.0:GL488356:6425:7851:-1 ge... [more]
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BLAST of SMED30035001 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of SMED30035001 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO426471.609e-1133.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO426121.658e-936.26Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO500682.778e-830.30Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO447941.501e-729.29Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of SMED30035001 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plac8l12.340e-1539.13PLAC8 like 1 [Source:NCBI gene;Acc:101175585][more]
ENSORLT00000012432.26.399e-1230.77cornifelin-like [Source:NCBI gene;Acc:101164880][more]
ENSORLT00000041395.16.399e-1230.77cornifelin-like [Source:NCBI gene;Acc:101164880][more]
ponzr36.476e-1234.34cornifelin homolog A [Source:NCBI gene;Acc:1011601... [more]
ENSORLT00000028572.18.304e-1231.30cornifelin homolog [Source:NCBI gene;Acc:101172524... [more]
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BLAST of SMED30035001 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000050244.15.044e-95100.00SMESG000050244.1[more]
SMESG000050244.11.811e-9097.67SMESG000050244.1[more]
SMESG000050245.11.832e-8086.82SMESG000050245.1[more]
SMESG000050175.13.216e-4557.69SMESG000050175.1[more]
SMESG000050177.14.803e-4252.59SMESG000050177.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30035001 ID=SMED30035001|Name=SMED30035001|organism=Schmidtea mediterranea sexual|type=transcript|length=469bp
TTTTTTTTAAAGTCACACTAAAGTTTACGAATATGAACAAAATTATGTTT
TCAATCAAAATAAAATTGAATTGATGATTTATTCGAGGTATCCGTTTTTA
TCCTCCACATAGTCCATGTCGCGTTTCAGTTGGCACATTGCGCAAAAGTA
ACACCAATAAGTTAGACAGCAATCAGCTATGATACTTCCTTTAATATGGT
TTCTGCTTCTATGTTTTGTTCTTAAAAGTAATGTTGAAGCTGGAGTAAAT
AAGGGAGTGCAAACGAATTCATAGTAGATATGGTACATGTAACAGAGATA
ACATTCAGGACAAAATGCAATTAGAACACAAGATGTGCAGTCATCACAAC
AGTCAAATAATCCCGAACTCCAATTCCTATAAGTGGTTCTTGGTATTTGA
TCCTGCCTGGTAATGACTGGTGCTACTTGGTTTTTATGGCCAGGTTGCGT
TATGATTACTGTAGTCATT
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000099neuron
PLANA:0000421tail
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR006461PLAC_motif_containing
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006461PLAC8 motif-containing proteinTIGRFAMTIGR01571TIGR01571coord: 31..118
e-value: 7.3E-15
score: 53.6
IPR006461PLAC8 motif-containing proteinPFAMPF04749PLAC8coord: 33..116
e-value: 8.0E-13
score: 49.2
IPR006461PLAC8 motif-containing proteinPANTHERPTHR15907FAMILY NOT NAMEDcoord: 3..122
NoneNo IPR availablePANTHERPTHR15907:SF93PLACENTA-SPECIFIC 8, TANDEM DUPLICATE 1-RELATEDcoord: 3..122