Adhesion G protein-coupled receptor L3

Overview
NameAdhesion G protein-coupled receptor L3
Smed IDSMED30034960
Length (bp)2721
Neoblast Clusters

Zeng et. al., 2018




▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 



 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)




Explore this single cell expression dataset with our NB Cluster Shiny App




 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Adhesion G protein-coupled receptor L3 (SMED30034960) t-SNE clustered cells

Violin plots show distribution of expression levels for Adhesion G protein-coupled receptor L3 (SMED30034960) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Adhesion G protein-coupled receptor L3 (SMED30034960) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Adhesion G protein-coupled receptor L3 (SMED30034960) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017




Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020




SMED30034960

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
epidermisSMED30034960h1SMcG0003523 dd_Smed_v4_10094_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30034960h1SMcG0003524 dd_Smed_v4_10094_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018
FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
epidermisSMED30034960h1SMcG0003523 dd_Smed_v4_10094_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
epidermisSMED30034960h1SMcG0003524 dd_Smed_v4_10094_0_1dd_Smed_v4PMID:28292427
Wurtzel et al., 2017
whole organism asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Zebrafish
Match: adgre5b.3 (adhesion G protein-coupled receptor E5b, duplicate 3 [Source:ZFIN;Acc:ZDB-GENE-121214-275])

HSP 1 Score: 63.929 bits (154), Expect = 7.534e-10
Identity = 103/417 (24.70%), Postives = 192/417 (46.04%), Query Frame = 1
Query:  868 KIPLIYKQSLNSLDSNQRAKIS-NSIIKNVQNLMKNVSIEVKNKNSSYQQISDS---FVIYSSVVTKPQMLIPSLN---LKNETNVQFVEINIKEKDK-------IKTGSSLV-----------------ANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERYKNSDIMYLSLS----RHTNLTVNFILRKIN-KLQSPSWLYLYEEECGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPI-NAWHL-LVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWI 2004
            ++P+  K+ L+ L S+  A ++ +   K  + LM+N+     +  S+   + D     V+  +V    +++ P L    ++ ET+  + E+ +            + TGS+L                   + + YKDM+  +  F+  N  R K+    D  +N T +      NS ++ + +S    +H +  V+ I   +  + +S +  Y     C Y  + S+ +WS +GC+    + +H  C C HLS+FA+L ++ P+ + + L L+T    + S +   + +  F         R+ +    L++++CL I  ++F+ G  ++ N++AC + A L  FFFLSAF W L+ GV + RM+  + +     L  Y +      Y V  +IV +S I   K YG   D  CW+
Sbjct:  220 EMPIKLKELLSQLRSSCEALVTPDGERKTGEQLMENLFTSTDDLLSA-GSVGDGETLSVLLDTVENSMRLICPQLKEPVMRMETHNTYAEVAVTRNQTPPSGSVILSTGSALFNTSWETVVGKSYPGFAFVSLVSYKDMNSSSNLFR--NVSRKKS----DMEENVTHKL-----NSKVVTVVVSNPDTKHLSEPVSLIFTHVEERAESKAVAY----NCVYWAE-SERAWSRQGCERAWSNSTHTECSCSHLSSFAVLMSLYPVQDTFELVLITRVGLVLSLLCLFLCILTFRFCRSIQGTRNSI---HLHLSVCLFIADLVFLCGISSTHNQVACAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYMYAVG-----YGVPLVIVSISAIAFPKGYG--TDRHCWL 609          
BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Zebrafish
Match: adgre5b.2 (adhesion G protein-coupled receptor E5b, duplicate 2 [Source:ZFIN;Acc:ZDB-GENE-121214-277])

HSP 1 Score: 57.3806 bits (137), Expect = 7.077e-8
Identity = 84/312 (26.92%), Postives = 146/312 (46.79%), Query Frame = 1
Query: 1135 DKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERYKNSDIMYLSLSRHTNLTVNFILRKINKLQSPSWLYLYEEE----------CGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPINA--WHLLVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWIESQSPAFLTF 2034
             K  +G + VA F  YKDM+  ++     ++   ++     KR +  E+KI    NS ++       T +  N   +K++ L   +  + +EEE          C Y ++ S+  WS +GC     + +H  C   HLS+FA+L  + P+      +L+T    + S +   + +  F         R+ +    L++++CL I  ++F+ G  ++ N++AC + A L  FFFLSAF W L+ GV + RM+  + +     L  Y +      Y V  +IV +S IT  K YG   +  CW+  +    L+F
Sbjct:  263 GKAYSGFAFVALFS-YKDMNSSSDLSHKTSRTLQED---SRKRLHVDEKKITYQLNSKVV-------TAVVSNPDTKKLSDLMMLT--FTHEEERAESGGVAYTCVYWNE-SEKVWSGRGCVKEWSNSTHTVCHWSHLSSFAVLMALYPVQDTFASVLITRVGLVLSLLCLFLCILTFRFCRSIQGTRNSI---HLHLSVCLFIADLVFLCGISSTHNQVACAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYLYAVG-----YGVPLVIVSISAITFPKGYG--TNKHCWLSLEGYLILSF 550          
BLAST of Adhesion G protein-coupled receptor L3 vs. TrEMBL
Match: A0A193KUQ6 (GCR144 OS=Schmidtea mediterranea OX=79327 GN=gcr144 PE=2 SV=1)

HSP 1 Score: 173.711 bits (439), Expect = 1.948e-44
Identity = 128/277 (46.21%), Postives = 181/277 (65.34%), Query Frame = 1
Query: 1654 NPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWIESQSPAFLTFXXXXXXXXXXXXXXXXXXXXHLFKHFIKSRKIKVNKSNESIIFFQLVITMGMTWVPSYFAIVYLEAMYMWIICFPLQGXXXXXXXXXINKENRAKVSSFVKDKYNSLISKTSQLSPSNFDSKFKSR------SVSKTSRAFIVDESETNS 2466
            N RDK+RL QLNI+ICLL GT++ +   F+  N++ CK+ AL  QF FLSAF WKLI G+N  R +  LKY+ E+ + K    + LS YS+   IV  SG   W+ YGK   D CWI+S     L F+IPI IIL +N + L +I   LF ++I++RK KVN+S E +IF QL++TMG+TWV +YF I +L A Y+++ICFPLQGL++ L VV+I++ENR+K+ +F+  KY+SL +K+S  S    D   + R      +V+K   +  VDE+E  S
Sbjct:   27 NSRDKMRLVQLNISICLLFGTVVILISDFSLHNQLLCKMMALSTQFLFLSAFVWKLILGINAFRGIVLLKYQQEDWMLKRPFVAVLSGYSIPLAIVSASGGLNWQKYGKDFLDGCWIQSD-IYLLWFLIPITIILFLNCIFLFLIGKALFHNYIRTRKTKVNESQEFLIFLQLMMTMGITWVTAYFGIFFLWAKYIFVICFPLQGLMMFLFVVIISQENRSKLINFISTKYSSLTTKSSSHSEEKRDFTTRQRTNSSNLAVNKILLSSFVDETEIVS 302          
BLAST of Adhesion G protein-coupled receptor L3 vs. TrEMBL
Match: E7F287 (Adhesion G protein-coupled receptor E5b, duplicate 3 OS=Danio rerio OX=7955 GN=adgre5b.3 PE=1 SV=3)

HSP 1 Score: 63.929 bits (154), Expect = 1.686e-6
Identity = 103/417 (24.70%), Postives = 192/417 (46.04%), Query Frame = 1
Query:  868 KIPLIYKQSLNSLDSNQRAKIS-NSIIKNVQNLMKNVSIEVKNKNSSYQQISDS---FVIYSSVVTKPQMLIPSLN---LKNETNVQFVEINIKEKDK-------IKTGSSLV-----------------ANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERYKNSDIMYLSLS----RHTNLTVNFILRKIN-KLQSPSWLYLYEEECGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPI-NAWHL-LVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWI 2004
            ++P+  K+ L+ L S+  A ++ +   K  + LM+N+     +  S+   + D     V+  +V    +++ P L    ++ ET+  + E+ +            + TGS+L                   + + YKDM+  +  F+  N  R K+    D  +N T +      NS ++ + +S    +H +  V+ I   +  + +S +  Y     C Y  + S+ +WS +GC+    + +H  C C HLS+FA+L ++ P+ + + L L+T    + S +   + +  F         R+ +    L++++CL I  ++F+ G  ++ N++AC + A L  FFFLSAF W L+ GV + RM+  + +     L  Y +      Y V  +IV +S I   K YG   D  CW+
Sbjct:  220 EMPIKLKELLSQLRSSCEALVTPDGERKTGEQLMENLFTSTDDLLSA-GSVGDGETLSVLLDTVENSMRLICPQLKEPVMRMETHNTYAEVAVTRNQTPPSGSVILSTGSALFNTSWETVVGKSYPGFAFVSLVSYKDMNSSSNLFR--NVSRKKS----DMEENVTHKL-----NSKVVTVVVSNPDTKHLSEPVSLIFTHVEERAESKAVAY----NCVYWAE-SERAWSRQGCERAWSNSTHTECSCSHLSSFAVLMSLYPVQDTFELVLITRVGLVLSLLCLFLCILTFRFCRSIQGTRNSI---HLHLSVCLFIADLVFLCGISSTHNQVACAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYMYAVG-----YGVPLVIVSISAIAFPKGYG--TDRHCWL 609          
BLAST of Adhesion G protein-coupled receptor L3 vs. TrEMBL
Match: A0A498M339 (CD97 antigen-like protein OS=Labeo rohita OX=84645 GN=ROHU_028188 PE=3 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 3.498e-6
Identity = 64/198 (32.32%), Postives = 100/198 (50.51%), Query Frame = 1
Query: 1417 CGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPI-NAWHL-LVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWI 2004
            C Y D+ ++ +WS +GC+    + +H  C C HLS+FA+L  + P+ + + L L+T      S +   + +  F         R  +    L+++ICL I  +IF+ G  ++ NK+ C + A L  FFFLSAF W L+ GV + RM+  + +     L  Y     L  Y V  +IV +S I   K YG   D  CW+
Sbjct:  391 CVYWDE-TEGAWSGRGCERAWSNSTHTACSCSHLSSFAVLMALYPVQDTFELVLITRLGLALSLVCLFLCILTFRFCRSIQGTRTSI---HLHLSICLFIADLIFLCGISSTQNKVGCAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYLY-----LVGYGVPLVIVIISAIAYPKGYG--TDRHCWL 577          
BLAST of Adhesion G protein-coupled receptor L3 vs. TrEMBL
Match: A0A498P3U8 (CD97 antigen-like protein OS=Labeo rohita OX=84645 GN=ROHU_000272 PE=3 SV=1)

HSP 1 Score: 62.7734 bits (151), Expect = 4.213e-6
Identity = 64/198 (32.32%), Postives = 100/198 (50.51%), Query Frame = 1
Query: 1417 CGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPI-NAWHL-LVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWI 2004
            C Y D+ ++ +WS +GC+    + +H  C C HLS+FA+L  + P+ + + L L+T      S +   + +  F         R  +    L+++ICL I  +IF+ G  ++ NK+ C + A L  FFFLSAF W L+ GV + RM+  + +     L  Y     L  Y V  +IV +S I   K YG   D  CW+
Sbjct:  415 CVYWDE-TEGAWSGRGCERAWSNSTHTACSCSHLSSFAVLMALYPVQDTFELVLITRLGLALSLVCLFLCILTFRFCRSIQGTRTSI---HLHLSICLFIADLIFLCGISSTQNKVGCAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTTLKHLYLY-----LVGYGVPLVIVIISAIAYPKGYG--TDRHCWL 601          
BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Nematostella
Match: EDO48598 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RJ05])

HSP 1 Score: 49.2914 bits (116), Expect = 3.412e-6
Identity = 22/52 (42.31%), Postives = 31/52 (59.62%), Query Frame = 1
Query: 1396 LYLYEEECGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKP 1551
            L + E  C Y DK    SWS +GCK+ + + SH +C CDHL++F   F + P
Sbjct:    8 LKVSEASCMYFDKMIG-SWSNEGCKVRQSNSSHVHCLCDHLTSFGGDFLVAP 58          
BLAST of Adhesion G protein-coupled receptor L3 vs. Planmine SMEST
Match: SMESG000009859.1 (SMESG000009859.1)

HSP 1 Score: 751.895 bits (1940), Expect = 0.000e+0
Identity = 394/401 (98.25%), Postives = 399/401 (99.50%), Query Frame = 1
Query:   97 FKRNLLLFVYLFCINFNIFANLQNLYSIKNRYGEIRRDNCVSTCFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKLCGNRIETCEPNLVNIKYAPVKQTTKNQYKIXXXXXXXXXXXXIFYKYITCKQEPLRFSLKIDKHFLYQNQIIFPFNVMRQIRMPNKNVVIKLSIWKNANEHLTEIDFYITKNRTDIVSFTESNFY-TSKLTNEQNIKSFVSIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERY 1296
            FKRNLLLFVYLFCINFNIFANLQNLYS+KNRYGEIRRDNCVSTCFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKLCGNRIETCEPN+VNIKYAPVKQTTKNQYKIPVSVVVPHSSSSIFYKYITCKQEPLRFSLKIDK+FLYQNQIIFPFNVMRQ+ +PNKNVVIKLSIWKNANEHLTEIDFYITKNRTDIVSFTESNFY TSKLTNEQNIKSFVSIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERY
Sbjct:    8 FKRNLLLFVYLFCINFNIFANLQNLYSVKNRYGEIRRDNCVSTCFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKLCGNRIETCEPNMVNIKYAPVKQTTKNQYKIPVSVVVPHSSSSIFYKYITCKQEPLRFSLKIDKNFLYQNQIIFPFNVMRQMSLPNKNVVIKLSIWKNANEHLTEIDFYITKNRTDIVSFTESNFYTTSKLTNEQNIKSFVSIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERY 408          
BLAST of Adhesion G protein-coupled receptor L3 vs. Planmine SMEST
Match: SMESG000009859.1 (SMESG000009859.1)

HSP 1 Score: 750.74 bits (1937), Expect = 0.000e+0
Identity = 394/401 (98.25%), Postives = 399/401 (99.50%), Query Frame = 1
Query:   97 FKRNLLLFVYLFCINFNIFANLQNLYSIKNRYGEIRRDNCVSTCFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKLCGNRIETCEPNLVNIKYAPVKQTTKNQYKIXXXXXXXXXXXXIFYKYITCKQEPLRFSLKIDKHFLYQNQIIFPFNVMRQIRMPNKNVVIKLSIWKNANEHLTEIDFYITKNRTDIVSFTESNFY-TSKLTNEQNIKSFVSIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERY 1296
            FKRNLLLFVYLFCINFNIFANLQNLYS+KNRYGEIRRDNCVSTCFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKLCGNRIETCEPN+VNIKYAPVKQTTKNQYKIPVSVVVPHSSSSIFYKYITCKQEPLRFSLKIDK+FLYQNQIIFPFNVMRQ+ +PNKNVVIKLSIWKNANEHLTEIDFYITKNRTDIVSFTESNFY TSKLTNEQNIKSFVSIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERY
Sbjct:    4 FKRNLLLFVYLFCINFNIFANLQNLYSVKNRYGEIRRDNCVSTCFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKLCGNRIETCEPNMVNIKYAPVKQTTKNQYKIPVSVVVPHSSSSIFYKYITCKQEPLRFSLKIDKNFLYQNQIIFPFNVMRQMSLPNKNVVIKLSIWKNANEHLTEIDFYITKNRTDIVSFTESNFYTTSKLTNEQNIKSFVSIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFTERKIERY 404          
BLAST of Adhesion G protein-coupled receptor L3 vs. Planmine SMEST
Match: SMESG000009861.1 (SMESG000009861.1)

HSP 1 Score: 564.303 bits (1453), Expect = 0.000e+0
Identity = 366/367 (99.73%), Postives = 367/367 (100.00%), Query Frame = 1
Query: 1531 MLFTIKPINAWHLLVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWIESQSPAFLTFXXXXXXXXXXXXXXXXXXXXHLFKHFIKSRKIKVNKSNESIIFFQLVITMGMTWVPSYFAIVYLEAMYMWIICFPLQGXXXXXXXXXINKENRAKVSSFVKDKYNSLISKTSQLSPSNFDSKFKSRSVSKTSRAFIVDESETNSTLLNSPNENKLLLSETSTPNFQFKELVNKVKQASESNTPGKVLLVPGSQPIFFKS 2631
            MLFTIKPINAWHLLVTGHLSIFSGIINIISLSLFLTFILHINPRDKLRLDQLNIAICLLIGTIIFIFGGFNSMNKIACKLTALLAQFFFLSAFNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIAD+VCWIESQSPAFLTFIIPIGIILVVNIVCLIVISIHLFKHFIKSRKIKVNKSNESIIFFQLVITMGMTWVPSYFAIVYLEAMYMWIICFPLQGLLLMLLVVVINKENRAKVSSFVKDKYNSLISKTSQLSPSNFDSKFKSRSVSKTSRAFIVDESETNSTLLNSPNENKLLLSETSTPNFQFKELVNKVKQASESNTPGKVLLVPGSQPIFFKS
Sbjct:    1 MLFTIKPINAWHLLVTGHLSIFSGIINIISLSLFLTFILHINPRDKLRLDQLNIAICLLIGTIIFIFGGFNSMNKIACKLTALLAQFFFLSAFNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADNVCWIESQSPAFLTFIIPIGIILVVNIVCLIVISIHLFKHFIKSRKIKVNKSNESIIFFQLVITMGMTWVPSYFAIVYLEAMYMWIICFPLQGLLLMLLVVVINKENRAKVSSFVKDKYNSLISKTSQLSPSNFDSKFKSRSVSKTSRAFIVDESETNSTLLNSPNENKLLLSETSTPNFQFKELVNKVKQASESNTPGKVLLVPGSQPIFFKS 367          
BLAST of Adhesion G protein-coupled receptor L3 vs. Planmine SMEST
Match: SMESG000009827.1 (SMESG000009827.1)

HSP 1 Score: 347.436 bits (890), Expect = 2.954e-104
Identity = 255/582 (43.81%), Postives = 369/582 (63.40%), Query Frame = 1
Query:  793 SIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSI-EVKNKNSSYQQISDSFVIYSSVV--TKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKN-LIIHDKRQNFTERKIERYKNSDIMYLSLSRHTNLTVNFILRKINKLQSPSWLYLYEEECGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPINAWHLLVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWIESQSPAFLTFXXXXXXXXXXXXXXXXXXXXHLFKHFIKSRKIKVNKSNESIIFFQLVITMGMTWVPSYFAIVYLEAMYMWIICFPLQGXXXXXXXXXINKENRAKVSSFVKDKYNSLISKTSQLSPSNFDSKFKSRSVSKTSRAFIVDESETNSTLLNSPNENKLLLSETSTPN 2526
            + F  I N++ +   KL+  +    K+   +K     +D  Q+   S  +++ ++  +  + + E+    +S  + S+ +  Y+S +  T+ + +IP    K      FV++ ++    I+T   L+  FI +KD+D+++E  + + +I+N + L + D      +  +ER+KNSD + LSL+   N+T+ F L    K+QS  WLY +EEECGYL  + +W WS  GC+ V  S +  YC CDHLSNFAMLF++K +N  HL +  +LS+F  IINI+SL  FLTF+L IN RDKLRLDQLNIAICLL+GTI F  G   ++N+I C++ A+  QF FLSAF WKLI G+NV+RM+A L+Y+NE+ + KYR+ +    Y +  +IV +SG   W  YG I+DDVCWI+S S AFLTFIIPIGIIL VN++ L  I   L ++++ +RK KVN+SNE ++F QL  +MG+TW+PSYFA VYL AMYMW++ FPLQGL++ L VVVIN+ENR KVSSFV +KY+SLISK++  S +   SK KS + SK         +E N +LL S  E  +       PN
Sbjct:  445 AFFKSIVNKSLSGDAKLNILMKETRKLSNNFKNVFTKVDVRQKKNTSRFLLRQIEKYVDQIFLKELDMNQTSLTRSSEEYDAYTSYIDETENEHVIPFSENKTHPEPLFVKLKLQTNGNIQTSEKLITTFIRFKDLDLIDESKKAELKIQNSSELKLKD------DDVVERFKNSDFISLSLNHKRNVTIQFKLPTFQKVQSQIWLYSFEEECGYLADDKNWEWSVDGCRKVIESSNQFYCECDHLSNFAMLFSVKTVNVIHLTIFKYLSVFGTIINILSLVFFLTFVLWINSRDKLRLDQLNIAICLLLGTIAFSLGSVVAVNQIFCQIVAIFTQFLFLSAFVWKLILGINVVRMIASLRYQNEDWMVKYRLVTLGVGYGIPLVIVIISGSIYWSAYGSISDDVCWIKSSSKAFLTFIIPIGIILAVNLIALFFIGNALIRNYLDTRKTKVNESNELMVFMQLFASMGLTWLPSYFATVYLVAMYMWVLFFPLQGLMMFLFVVVINRENREKVSSFVIEKYSSLISKSTSSSDTRTHSKSKSTTHSKV--------TEHNQSLL-SETEKDMAFPMIKIPN 1011          
BLAST of Adhesion G protein-coupled receptor L3 vs. Planmine SMEST
Match: SMESG000009827.1 (SMESG000009827.1)

HSP 1 Score: 347.821 bits (891), Expect = 4.186e-104
Identity = 255/582 (43.81%), Postives = 369/582 (63.40%), Query Frame = 1
Query:  793 SIFDKIFNENQNYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNVSI-EVKNKNSSYQQISDSFVIYSSVV--TKPQMLIPSLNLKNETNVQFVEINIKEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKN-LIIHDKRQNFTERKIERYKNSDIMYLSLSRHTNLTVNFILRKINKLQSPSWLYLYEEECGYLDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPINAWHLLVTGHXXXXXXXXXXXXXXXXXXXXXXXNPRDKLRLDQLNIAICLLXXXXXXXXXXXNSMNKIACKXXXXXXXXXXXXXXNWKLIYGVNVIRMMAFLKYENENKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWIESQSPAFLTFXXXXXXXXXXXXXXXXXXXXHLFKHFIKSRKIKVNKSNESIIFFQLVITMGMTWVPSYFAIVYLEAMYMWIICFPLQGXXXXXXXXXINKENRAKVSSFVKDKYNSLISKTSQLSPSNFDSKFKSRSVSKTSRAFIVDESETNSTLLNSPNENKLLLSETSTPN 2526
            + F  I N++ +   KL+  +    K+   +K     +D  Q+   S  +++ ++  +  + + E+    +S  + S+ +  Y+S +  T+ + +IP    K      FV++ ++    I+T   L+  FI +KD+D+++E  + + +I+N + L + D      +  +ER+KNSD + LSL+   N+T+ F L    K+QS  WLY +EEECGYL  + +W WS  GC+ V  S +  YC CDHLSNFAMLF++K +N  HL +  +LS+F  IINI+SL  FLTF+L IN RDKLRLDQLNIAICLL+GTI F  G   ++N+I C++ A+  QF FLSAF WKLI G+NV+RM+A L+Y+NE+ + KYR+ +    Y +  +IV +SG   W  YG I+DDVCWI+S S AFLTFIIPIGIIL VN++ L  I   L ++++ +RK KVN+SNE ++F QL  +MG+TW+PSYFA VYL AMYMW++ FPLQGL++ L VVVIN+ENR KVSSFV +KY+SLISK++  S +   SK KS + SK         +E N +LL S  E  +       PN
Sbjct:  472 AFFKSIVNKSLSGDAKLNILMKETRKLSNNFKNVFTKVDVRQKKNTSRFLLRQIEKYVDQIFLKELDMNQTSLTRSSEEYDAYTSYIDETENEHVIPFSENKTHPEPLFVKLKLQTNGNIQTSEKLITTFIRFKDLDLIDESKKAELKIQNSSELKLKD------DDVVERFKNSDFISLSLNHKRNVTIQFKLPTFQKVQSQIWLYSFEEECGYLADDKNWEWSVDGCRKVIESSNQFYCECDHLSNFAMLFSVKTVNVIHLTIFKYLSVFGTIINILSLVFFLTFVLWINSRDKLRLDQLNIAICLLLGTIAFSLGSVVAVNQIFCQIVAIFTQFLFLSAFVWKLILGINVVRMIASLRYQNEDWMVKYRLVTLGVGYGIPLVIVIISGSIYWSAYGSISDDVCWIKSSSKAFLTFIIPIGIILAVNLIALFFIGNALIRNYLDTRKTKVNESNELMVFMQLFASMGLTWLPSYFATVYLVAMYMWVLFFPLQGLMMFLFVVVINRENREKVSSFVIEKYSSLISKSTSSSDTRTHSKSKSTTHSKV--------TEHNQSLL-SETEKDMAFPMIKIPN 1038          
The following BLAST results are available for this feature:
BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
adgre5b.37.534e-1024.70adhesion G protein-coupled receptor E5b, duplicate... [more]
adgre5b.27.077e-826.92adhesion G protein-coupled receptor E5b, duplicate... [more]
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 4
Match NameE-valueIdentityDescription
A0A193KUQ61.948e-4446.21GCR144 OS=Schmidtea mediterranea OX=79327 GN=gcr14... [more]
E7F2871.686e-624.70Adhesion G protein-coupled receptor E5b, duplicate... [more]
A0A498M3393.498e-632.32CD97 antigen-like protein OS=Labeo rohita OX=84645... [more]
A0A498P3U84.213e-632.32CD97 antigen-like protein OS=Labeo rohita OX=84645... [more]
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO485983.412e-642.31Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Adhesion G protein-coupled receptor L3 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of Adhesion G protein-coupled receptor L3 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5
Match NameE-valueIdentityDescription
SMESG000009859.10.000e+098.25SMESG000009859.1[more]
SMESG000009859.10.000e+098.25SMESG000009859.1[more]
SMESG000009861.10.000e+099.73SMESG000009861.1[more]
SMESG000009827.12.954e-10443.81SMESG000009827.1[more]
SMESG000009827.14.186e-10443.81SMESG000009827.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034960 ID=SMED30034960|Name=Adhesion G protein-coupled receptor L3|organism=Schmidtea mediterranea sexual|type=transcript|length=2721bp
GTAAATGATAACGATTTGAAAAATTTTTTATAATTATAAACTGTAATTAT
AAACTATATTTCAAAAATTATAAAAATGATAATATTAATGGTAATATTCA
AAAGAAATTTATTGTTGTTTGTCTATTTGTTTTGTATAAATTTTAATATT
TTTGCTAATTTACAAAACCTTTACTCGATCAAAAACAGATATGGAGAAAT
AAGAAGAGACAATTGCGTTTCGACTTGCTTCGACTTAAAACCTAGCAATT
TAGTCTTGGAGATTTCTGATTCCGATAACAAAACATCGAAGTCAATTGCA
ATTATTTATAAATGTCCGATCAACGAAATAGATGTCTATGATCCGCTTTT
CAATAAAAATAAATACGTAAAACTGTGCGGAAATAGAATTGAAACATGCG
AGCCTAATCTGGTCAACATTAAGTACGCTCCTGTAAAACAAACTACAAAA
AATCAGTATAAGATTCCGGTATCAGTTGTTGTTCCACATTCTTCAAGCAG
TATATTTTACAAATATATTACCTGTAAACAAGAACCGTTGAGATTTTCTT
TAAAAATAGACAAACATTTTCTTTATCAAAACCAAATCATATTTCCTTTT
AATGTTATGAGACAAATAAGAATGCCAAATAAGAATGTGGTAATAAAGTT
ATCTATTTGGAAGAATGCCAATGAACATTTGACAGAAATAGACTTTTACA
TTACGAAAAATCGGACAGATATTGTTTCTTTTACAGAAAGTAACTTTTAT
ACTTCTAAATTGACAAATGAACAGAATATAAAAAGTTTTGTATCAATTTT
TGATAAAATATTTAATGAAAATCAAAATTACAAAGTAAAGTTGTCGAAAG
CATTATCAATGGTTACAAAAATCCCTCTAATTTATAAACAATCATTGAAT
TCTTTGGATTCAAATCAAAGAGCAAAAATATCTAATTCAATTATTAAAAA
TGTTCAAAATTTAATGAAAAATGTATCCATCGAAGTAAAAAATAAAAATA
GTTCGTATCAGCAAATATCTGATTCATTCGTCATTTACAGTTCTGTAGTC
ACCAAACCACAAATGCTCATTCCTTCTTTAAATTTAAAAAACGAAACTAA
TGTACAATTTGTCGAGATTAATATTAAAGAGAAAGACAAAATAAAAACGG
GTTCTAGTCTTGTTGCAAATTTTATTTTATACAAAGACATGGACATCATG
AATGAATATTTTCAAATACAAAATCAAATAAGAAATAAAAATTTAATTAT
TCATGATAAACGTCAAAATTTTACAGAAAGAAAAATTGAAAGATATAAAA
ATTCTGATATAATGTATTTGTCCCTGAGCAGACATACTAATCTAACTGTC
AATTTTATACTGAGAAAAATAAACAAGTTACAATCTCCTTCATGGCTGTA
TTTATATGAAGAAGAATGTGGATATTTGGATAAAAATAGTGATTGGAGCT
GGTCAACAAAGGGATGCAAAATAGTTAAAGGAAGTGACAGTCATCATTAT
TGCCGTTGTGATCACTTATCAAATTTCGCAATGCTTTTTACAATTAAACC
TATAAATGCCTGGCATTTATTAGTTACTGGACACCTTTCCATATTTAGTG
GTATCATAAATATCATTTCATTGTCATTATTTCTCACATTTATTTTACAC
ATAAATCCAAGAGATAAATTAAGACTGGATCAGCTAAATATTGCTATTTG
CTTGTTGATCGGGACGATCATTTTTATATTCGGCGGCTTTAATAGCATGA
ATAAAATAGCATGTAAATTAACCGCATTATTGGCTCAATTCTTTTTTTTA
TCTGCATTCAATTGGAAACTGATCTATGGAGTAAATGTTATTCGAATGAT
GGCCTTTCTAAAATATGAAAATGAAAACAAGCTGCGTAAATACCGAATAG
CTTCAACCTTATCGAGTTACAGTGTTTCGTTTTTAATTGTGTTTTTATCG
GGAATTACGCAATGGAAGTATTATGGTAAAATTGCTGATGACGTCTGTTG
GATCGAAAGTCAAAGTCCAGCCTTCTTGACATTTATCATTCCAATAGGAA
TTATTCTTGTTGTGAATATTGTTTGTTTAATAGTTATTTCCATTCATCTA
TTTAAGCATTTCATCAAAAGTCGAAAAATAAAAGTTAATAAATCAAATGA
GTCGATAATTTTTTTCCAATTAGTAATTACAATGGGGATGACATGGGTAC
CGTCATACTTTGCTATTGTTTATTTAGAGGCCATGTACATGTGGATTATC
TGTTTTCCACTTCAGGGTCTTTTGCTGATGTTACTTGTCGTTGTTATTAA
CAAAGAAAATAGAGCCAAAGTTTCTAGTTTCGTAAAAGATAAATATAATT
CATTAATTTCGAAAACATCTCAATTATCGCCATCAAATTTTGATTCAAAG
TTTAAGTCACGTTCTGTATCAAAAACATCGAGAGCCTTCATTGTGGATGA
AAGTGAAACGAATTCCACACTATTAAACAGCCCTAACGAAAACAAGTTAT
TGCTATCTGAAACTTCGACACCAAACTTTCAATTTAAAGAACTTGTAAAT
AAAGTTAAACAAGCATCCGAAAGTAATACACCAGGAAAAGTCTTATTGGT
ACCAGGAAGTCAGCCAATATTTTTTAAATCCTGAGAAATTCTGCGAAAAA
CTCTATAATTTTAAGTACATTTAAGCTATTTCATTATAATTGTGCGAATG
CTTAAACGACACTAAAATTGG
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protein sequence of SMED30034960-orf-1

>SMED30034960-orf-1 ID=SMED30034960-orf-1|Name=SMED30034960-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=853bp
MIILMVIFKRNLLLFVYLFCINFNIFANLQNLYSIKNRYGEIRRDNCVST
CFDLKPSNLVLEISDSDNKTSKSIAIIYKCPINEIDVYDPLFNKNKYVKL
CGNRIETCEPNLVNIKYAPVKQTTKNQYKIPVSVVVPHSSSSIFYKYITC
KQEPLRFSLKIDKHFLYQNQIIFPFNVMRQIRMPNKNVVIKLSIWKNANE
HLTEIDFYITKNRTDIVSFTESNFYTSKLTNEQNIKSFVSIFDKIFNENQ
NYKVKLSKALSMVTKIPLIYKQSLNSLDSNQRAKISNSIIKNVQNLMKNV
SIEVKNKNSSYQQISDSFVIYSSVVTKPQMLIPSLNLKNETNVQFVEINI
KEKDKIKTGSSLVANFILYKDMDIMNEYFQIQNQIRNKNLIIHDKRQNFT
ERKIERYKNSDIMYLSLSRHTNLTVNFILRKINKLQSPSWLYLYEEECGY
LDKNSDWSWSTKGCKIVKGSDSHHYCRCDHLSNFAMLFTIKPINAWHLLV
TGHLSIFSGIINIISLSLFLTFILHINPRDKLRLDQLNIAICLLIGTIIF
IFGGFNSMNKIACKLTALLAQFFFLSAFNWKLIYGVNVIRMMAFLKYENE
NKLRKYRIASTLSSYSVSFLIVFLSGITQWKYYGKIADDVCWIESQSPAF
LTFIIPIGIILVVNIVCLIVISIHLFKHFIKSRKIKVNKSNESIIFFQLV
ITMGMTWVPSYFAIVYLEAMYMWIICFPLQGLLLMLLVVVINKENRAKVS
SFVKDKYNSLISKTSQLSPSNFDSKFKSRSVSKTSRAFIVDESETNSTLL
NSPNENKLLLSETSTPNFQFKELVNKVKQASESNTPGKVLLVPGSQPIFF
KS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000034epidermis
PLANA:0002032epidermal cell
Vocabulary: INTERPRO
TermDefinition
IPR000203GPS
IPR000832GPCR_2_secretin-like
IPR017981GPCR_2-like
IPR000651Ras-like_Gua-exchang_fac_N
Vocabulary: cellular component
TermDefinition
GO:0016020membrane
GO:0016021integral component of membrane
Vocabulary: molecular function
TermDefinition
GO:0004930G-protein coupled receptor activity
GO:0004888transmembrane signaling receptor activity
GO:0005509calcium ion binding
Vocabulary: biological process
TermDefinition
GO:0007186G-protein coupled receptor signaling pathway
GO:0007166cell surface receptor signaling pathway