VWFD domain-containing protein
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034930 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 10
Homology
BLAST of VWFD domain-containing protein vs. Ensembl Human
Match: ZAN (zonadhesin (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12857]) HSP 1 Score: 139.813 bits (351), Expect = 1.013e-31 Identity = 109/367 (29.70%), Postives = 163/367 (44.41%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTK-SGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKEL 1324
C GDPHY T+DG+ F G C Y L Q F + +NE +G +K + V L + L V GQ +P S V + S +F++ + +RV +DGD +V VS YS K+ G+CG+ +G D+ K G +K +GNS+ + C+K + ++ S C S+ CG L++ + PF C +V +FF C++DMC + Q + C S + C +AG WR CP+ C N+ +S A PCP TC + F G C D E C CN G++ G C+ C C++ + +W + G CKEL
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-VGGQQVTLPAIPSKGVFLGASGRFVE-LQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEE----LGNSWQTDQDEDQECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLL--HVKAASFFDSCMLDMCGFQG----LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMF--CSDRCV-EACECNPGFVLSGLECIPRSQCGCLHPA--GSYFKVGERWYKPG-CKEL 1503 HSP 2 Score: 113.235 bits (282), Expect = 9.815e-24 Identity = 101/374 (27.01%), Postives = 158/374 (42.25%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKD-WIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPC-YDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C P+R + Q C + + C+A GDPHY T+DG + HF G C Y LT+ +R D F + NE RG +Y K+V + +F L + + +NG +P + + L + ++V +DG V V Y ++ G+CG+ N D + R ++ + S+PG K S D W K+C +L+ P PFS+C + V ++ F CV C K + C A +C++AG + WR++ CP++C + +S ++PCP TC + R C LP E C C +G+I G CV C C +
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW------NKNCAILINPQGPFSQCHQV--VPPQSSFASCVHGQCGTKGDTT----ALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS--INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 1871 HSP 3 Score: 79.337 bits (194), Expect = 2.079e-13 Identity = 82/323 (25.39%), Postives = 136/323 (42.11%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIE---VQNEYRGDN-KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSK-----------PGHHCKKAKDISYH-----SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQ 1072
C + NC S + + +CS GDP Y T+DG G Y L + D +E V+ + D + + + VI ++ +L L VN Q VPY ++ +R+ + L V + V+F G NA + + Y ++G+CG+ + R +D SG N + GNS+ V P + ++ S C + + S + + C VL +P PF+ C + V F + CV+D+C ++ P +++RC++ SG A +C EAG WR + C Q
Sbjct: 2312 CQLTSDNSNSNCVSDKSE--QCSVYGDPRYLTFDGFSYRLQGRMTYVLI---KTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD-FELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQN----LNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQ--TVAPEPFQEHCVLDLCSAQD-PREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAGQ 2620
BLAST of VWFD domain-containing protein vs. Ensembl Human
Match: ZAN (zonadhesin (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12857]) HSP 1 Score: 139.813 bits (351), Expect = 1.071e-31 Identity = 109/367 (29.70%), Postives = 163/367 (44.41%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTK-SGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKEL 1324
C GDPHY T+DG+ F G C Y L Q F + +NE +G +K + V L + L V GQ +P S V + S +F++ + +RV +DGD +V VS YS K+ G+CG+ +G D+ K G +K +GNS+ + C+K + ++ S C S+ CG L++ + PF C +V +FF C++DMC + Q + C S + C +AG WR CP+ C N+ +S A PCP TC + F G C D E C CN G++ G C+ C C++ + +W + G CKEL
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-VGGQQVTLPAIPSKGVFLGASGRFVE-LQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEE----LGNSWQTDQDEDQECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLL--HVKAASFFDSCMLDMCGFQG----LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMF--CSDRCV-EACECNPGFVLSGLECIPRSQCGCLHPA--GSYFKVGERWYKPG-CKEL 1503 HSP 2 Score: 113.235 bits (282), Expect = 1.021e-23 Identity = 101/374 (27.01%), Postives = 158/374 (42.25%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKD-WIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPC-YDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C P+R + Q C + + C+A GDPHY T+DG + HF G C Y LT+ +R D F + NE RG +Y K+V + +F L + + +NG +P + + L + ++V +DG V V Y ++ G+CG+ N D + R ++ + S+PG K S D W K+C +L+ P PFS+C + V ++ F CV C K + C A +C++AG + WR++ CP++C + +S ++PCP TC + R C LP E C C +G+I G CV C C +
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW------NKNCAILINPQGPFSQCHQV--VPPQSSFASCVHGQCGTKGDTT----ALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS--INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 1871 HSP 3 Score: 66.6254 bits (161), Expect = 1.505e-9 Identity = 74/301 (24.58%), Postives = 126/301 (41.86%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIE---VQNEYRGD-NKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSK-----------PGHHCKKAKDISYH-----SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLA 1006
C + NC S + + +CS GDP Y T+DG G Y L + D +E V+ + D + + + VI ++ +L L VN Q VPY ++ +R+ + L V + V+F G NA + + Y ++G+CG+ + R +D SG N + GNS+ V P + ++ S C + + S + + C VL +P PF+ C + V F + CV+D+C ++ P +++RC++ SG A
Sbjct: 2312 CQLTSDNSNSNCVSDKSE--QCSVYGDPRYLTFDGFSYRLQGRMTYVLI---KTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD-FELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQN----LNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQ--TVAPEPFQEHCVLDLCSAQD-PREQEELRCQVLSGWA 2598
BLAST of VWFD domain-containing protein vs. Ensembl Human
Match: ZAN (zonadhesin (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12857]) HSP 1 Score: 139.428 bits (350), Expect = 1.335e-31 Identity = 109/367 (29.70%), Postives = 163/367 (44.41%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTK-SGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKEL 1324
C GDPHY T+DG+ F G C Y L Q F + +NE +G +K + V L + L V GQ +P S V + S +F++ + +RV +DGD +V VS YS K+ G+CG+ +G D+ K G +K +GNS+ + C+K + ++ S C S+ CG L++ + PF C +V +FF C++DMC + Q + C S + C +AG WR CP+ C N+ +S A PCP TC + F G C D E C CN G++ G C+ C C++ + +W + G CKEL
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-VGGQQVTLPAIPSKGVFLGASGRFVE-LQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEE----LGNSWQTDQDEDQECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLL--HVKAASFFDSCMLDMCGFQG----LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMF--CSDRCV-EACECNPGFVLSGLECIPRSQCGCLHPA--GSYFKVGERWYKPG-CKEL 1503 HSP 2 Score: 113.235 bits (282), Expect = 1.187e-23 Identity = 101/374 (27.01%), Postives = 158/374 (42.25%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKD-WIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPC-YDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C P+R + Q C + + C+A GDPHY T+DG + HF G C Y LT+ +R D F + NE RG +Y K+V + +F L + + +NG +P + + L + ++V +DG V V Y ++ G+CG+ N D + R ++ + S+PG K S D W K+C +L+ P PFS+C + V ++ F CV C K + C A +C++AG + WR++ CP++C + +S ++PCP TC + R C LP E C C +G+I G CV C C +
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW------NKNCAILINPQGPFSQCHQV--VPPQSSFASCVHGQCGTKGDTT----ALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS--INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 1871 HSP 3 Score: 98.5969 bits (244), Expect = 3.243e-19 Identity = 96/371 (25.88%), Postives = 155/371 (41.78%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIE---VQNEYRGDN-KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSK-----------PGHHCKKAKDISYH-----SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDG 1216
C + NC S + + +CS GDP Y T+DG G Y L + D +E V+ + D + + + VI ++ +L L VN Q VPY ++ +R+ + L V + V+F G NA + + Y ++G+CG+ + R +D SG N + GNS+ V P + ++ S C + + S + + C VL +P PF+ C + V F + CV+D+C ++ P +++RC++ SG A +C EAG WR + C ++C + PCP +C N C + P EGCA GY G
Sbjct: 2312 CQLTSDNSNSNCVSDKSE--QCSVYGDPRYLTFDGFSYRLQGRMTYVLI---KTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD-FELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQN----LNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQ--TVAPEPFQEHCVLDLCSAQD-PREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCAMECPAGTIYQSCMTPCPASCAN--LADPGDC-EGPCVEGCASIPGYAYSG 2665
BLAST of VWFD domain-containing protein vs. Ensembl Human
Match: ZAN (zonadhesin (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12857]) HSP 1 Score: 139.043 bits (349), Expect = 1.666e-31 Identity = 103/344 (29.94%), Postives = 154/344 (44.77%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTK-SGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG+ F G C Y L Q F + +NE +G +K + V L + L V GQ +P S V + S +F++ + +RV +DGD +V VS YS K+ G+CG+ +G D+ K G +K +GNS+ + C+K + ++ S C S+ CG L++ + PF C +V +FF C++DMC + Q + C S + C +AG WR CP+ C N+ +S A PCP TC + F G C D E C CN G++ G C+ C C++
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-VGGQQVTLPAIPSKGVFLGASGRFVE-LQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEE----LGNSWQTDQDEDQECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLL--HVKAASFFDSCMLDMCGFQG----LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMF--CSDRCV-EACECNPGFVLSGLECIPRSQCGCLH 1483 HSP 2 Score: 112.849 bits (281), Expect = 1.432e-23 Identity = 101/374 (27.01%), Postives = 158/374 (42.25%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKD-WIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPC-YDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C P+R + Q C + + C+A GDPHY T+DG + HF G C Y LT+ +R D F + NE RG +Y K+V + +F L + + +NG +P + + L + ++V +DG V V Y ++ G+CG+ N D + R ++ + S+PG K S D W K+C +L+ P PFS+C + V ++ F CV C K + C A +C++AG + WR++ CP++C + +S ++PCP TC + R C LP E C C +G+I G CV C C +
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW------NKNCAILINPQGPFSQCHQV--VPPQSSFASCVHGQCGTKGDTT----ALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS--INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 1871 HSP 3 Score: 85.5001 bits (210), Expect = 2.605e-15 Identity = 94/377 (24.93%), Postives = 153/377 (40.58%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIE---VQNEYRGDN-KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSK-----------PGHHCKKAKDISYH-----SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKP 1234
C + NC S + + +CS GDP Y T+DG G Y L + D +E V+ + D + + + VI ++ +L L VN Q VPY ++ +R+ + L V + V+F G NA + + Y ++G+CG+ + R +D SG N + GNS+ V P + ++ S C + + S + + C VL +P PF+ C + V F + CV+D+C ++ P +++RC++ SG A +C EAG WR + C C + NPC + C + C C GY G LC++P
Sbjct: 2312 CQLTSDNSNSNCVSDKSE--QCSVYGDPRYLTFDGFSYRLQGRMTYVLI---KTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD-FELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQN----LNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQ--TVAPEPFQEHCVLDLCSAQD-PREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQ--------NPCQNDGQ---------CREQGATFTCECEVGY--GGGLCMEP 2655
BLAST of VWFD domain-containing protein vs. Ensembl Human
Match: ZAN (zonadhesin (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:12857]) HSP 1 Score: 139.043 bits (349), Expect = 1.666e-31 Identity = 103/344 (29.94%), Postives = 154/344 (44.77%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTK-SGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG+ F G C Y L Q F + +NE +G +K + V L + L V GQ +P S V + S +F++ + +RV +DGD +V VS YS K+ G+CG+ +G D+ K G +K +GNS+ + C+K + ++ S C S+ CG L++ + PF C +V +FF C++DMC + Q + C S + C +AG WR CP+ C N+ +S A PCP TC + F G C D E C CN G++ G C+ C C++
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-VGGQQVTLPAIPSKGVFLGASGRFVE-LQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEE----LGNSWQTDQDEDQECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLL--HVKAASFFDSCMLDMCGFQG----LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMF--CSDRCV-EACECNPGFVLSGLECIPRSQCGCLH 1483 HSP 2 Score: 112.849 bits (281), Expect = 1.432e-23 Identity = 101/374 (27.01%), Postives = 158/374 (42.25%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKD-WIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPC-YDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C P+R + Q C + + C+A GDPHY T+DG + HF G C Y LT+ +R D F + NE RG +Y K+V + +F L + + +NG +P + + L + ++V +DG V V Y ++ G+CG+ N D + R ++ + S+PG K S D W K+C +L+ P PFS+C + V ++ F CV C K + C A +C++AG + WR++ CP++C + +S ++PCP TC + R C LP E C C +G+I G CV C C +
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW------NKNCAILINPQGPFSQCHQV--VPPQSSFASCVHGQCGTKGDTT----ALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS--INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 1871 HSP 3 Score: 85.5001 bits (210), Expect = 2.605e-15 Identity = 94/377 (24.93%), Postives = 153/377 (40.58%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIE---VQNEYRGDN-KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSK-----------PGHHCKKAKDISYH-----SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKP 1234
C + NC S + + +CS GDP Y T+DG G Y L + D +E V+ + D + + + VI ++ +L L VN Q VPY ++ +R+ + L V + V+F G NA + + Y ++G+CG+ + R +D SG N + GNS+ V P + ++ S C + + S + + C VL +P PF+ C + V F + CV+D+C ++ P +++RC++ SG A +C EAG WR + C C + NPC + C + C C GY G LC++P
Sbjct: 2312 CQLTSDNSNSNCVSDKSE--QCSVYGDPRYLTFDGFSYRLQGRMTYVLI---KTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD-FELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQN----LNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQ--TVAPEPFQEHCVLDLCSAQD-PREQEELRCQVLSGYAILCQEAGAALAGWRDRTLCESPCLQ--------NPCQNDGQ---------CREQGATFTCECEVGY--GGGLCMEP 2655
BLAST of VWFD domain-containing protein vs. Ensembl Celegans
Match: T01D3.6 (pep chromosome:WBcel235:V:13716824:13720402:1 gene:WBGene00011330.1 transcript:T01D3.6b.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T01D3.6) HSP 1 Score: 86.2705 bits (212), Expect = 4.550e-16 Identity = 101/431 (23.43%), Postives = 173/431 (40.14%), Query Frame = 2
Query: 158 NGVCTPFRT--KTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS--------FNIEVQNEYRGDNKYFTYTKSVIIHMFR-EVYELGQKGVLKVNGQLSRVPY----EKSDDVRI-FKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSK----RYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKY--------------SLIGNSYHVSKPGH-HCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPN---NPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFE---GIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPEREGCACNRGYIRDGAL-----CVKPMHCKCINLCVDRESSEKCRKWKQQ 1306
N +C P T + +C+ K + C GDPHY TYDG + G C Y +Q PC+ +++ +NE G + + V + + ++ G+ VNG P+ + + VR+ F F + V V F ++ V+V + + G+ G+ +G + DD K+G ++ K ++ + I + + + +PG +C + + ++ C A + C + + F C GN L +F+ +C+ D+C N +C F+ + C A + WR+Q NCPL C NAH S + CP TC F P Y D +GC C+ GY+ D + C++ C C++ D + + W Q
Sbjct: 165 NCICKPGYTARRNGRDCDMKVQQAC---MSGDPHYVTYDGLRFDYQGTCPYVFSQ------PCTTLPAPYLWYSVRAKNELPGKGYHISQVSEVEVDLHNLTIHVDGRSKTALVNGVQVLTPWYFPNKNTWTVRVRFSGSTFT--IENDQGVVVTFTTYNSLCVQVPDIPEFNGATTLCGLAGNIDGKKLDDVVNKNGSVLAIKSSRQPENNNHADFMKTEDTWITDKFLILRPGQENCINGQTLDNNTNC-----DVATASQTCYPIQQAEMGLGTFGACQGLGNDTLEDFYYNCIYDICRNP-------AFKCTEFTYFLQYCQLALPQVAMNQNWRAQINCPLACPLNAHPSTCTSSCPSTCAEPF-----PEYCDQGCVDGCECDPGYVIDNTVTGSIKCIRLDQCGCVD--SDGNAHRPGKPWVTQ 565
BLAST of VWFD domain-containing protein vs. Ensembl Celegans
Match: T01D3.6 (pep chromosome:WBcel235:V:13716849:13720402:1 gene:WBGene00011330.1 transcript:T01D3.6a.1 gene_biotype:protein_coding transcript_biotype:protein_coding gene_symbol:T01D3.6) HSP 1 Score: 65.4698 bits (158), Expect = 9.865e-10 Identity = 86/394 (21.83%), Postives = 154/394 (39.09%), Query Frame = 2
Query: 284 FYGDCRYTLTQHNREDDPCS--------FNIEVQNEYRGDNKYFTYTKSVIIHMFR-EVYELGQKGVLKVNGQLSRVPY----EKSDDVRI-FKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSK----RYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKY--------------SLIGNSYHVSKPGH-HCKKAKDISYHSICGKDWIRSLK-------AKKHCGVLLEPN---NPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFE---GIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPEREGCACNRGYIRDGAL-----CVKPMHCKCINLCVDRESSEKCRKWKQQ 1306
+ G C Y +Q PC+ +++ +NE G + + V + + ++ G+ VNG P+ + + VR+ F F + V V F ++ V+V + + G+ G+ +G + DD K+G ++ K ++ + I + + + +PG +C + + ++ C I + A + C + + F C GN L +F+ +C+ D+C N +C F+ + C A + WR+Q NCPL C NAH S + CP TC F P Y D +GC C+ GY+ D + C++ C C++ D + + W Q
Sbjct: 206 YQGTCPYVFSQ------PCTTLPAPYLWYSVRAKNELPGKGYHISQVSEVEVDLHNLTIHVDGRSKTALVNGVQVLTPWYFPNKNTWTVRVRFSGSTFT--IENDQGVVVTFTTYNSLCVQVPDIPEFNGATTLCGLAGNIDGKKLDDVVNKNGSVLAIKSSRQPENNNHADFMKTEDTWITDKFLILRPGQENCINGQTLDNNTNCVSTSISLAQSCADVATASQTCYPIQQAEMGLGTFGACQGLGNDTLEDFYYNCIYDICRNP-------AFKCTEFTYFLQYCQLALPQVAMNQNWRAQINCPLACPLNAHPSTCTSSCPSTCAEPF-----PEYCDQGCVDGCECDPGYVIDNTVTGSIKCIRLDQCGCVD--SDGNAHRPGKPWVTQ 577
BLAST of VWFD domain-containing protein vs. Ensembl Fly
Match: cv-2 (gene:FBgn0000395 transcript:FBtr0071610) HSP 1 Score: 99.3673 bits (246), Expect = 4.646e-20 Identity = 85/295 (28.81%), Postives = 136/295 (46.10%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPY---EKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVS--KRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFS 1096
C+ GDPH+RT+DG+ F G C+Y L +F+I + NE RG + ++ K+V + + LGQ+ +KVNG +PY +V I + V R + + + + F++VS ++ K++ G+CG+ NG RDD K GR S+ ++ NS+ V P +K + ++ C K K+ +C L P F +C + N + N+ C +D+C PS C+ F+ A C G + WRS NCP +NA S
Sbjct: 383 CTVFGDPHFRTFDGKFFSFQGSCKYLLASDCMGK---TFHIRLTNEGRGTRRA-SWAKTVTLSLRNLKVNLGQRMRVKVNGTRVTLPYFVVAGGQNVTIERLANG-GAVMLRSEMGLTLEWNGAGFLQVSVPAKFKKRLCGLCGNFNGSSRDDLTGKDGR--SHGDDEVWHFANSWKVGGPKSCSRKREFLAATPTCDKR-----KSNFYCHPLSVPAL-FGECNERLNPE--NYKAACRMDVC---ECPS--GDCHCDSFAAYAHECRRLGVQLPDWRSATNCPAGWRRNATLS 657
BLAST of VWFD domain-containing protein vs. Ensembl Fly
Match: Hml (gene:FBgn0029167 transcript:FBtr0333020) HSP 1 Score: 83.9593 bits (206), Expect = 4.147e-15 Identity = 96/368 (26.09%), Postives = 149/368 (40.49%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTL-----TQHNREDDPCSFNI-EVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKS----------DDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQF-NCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER--------EGCACNRG-YIRDGALCVKPMHCKC 1249
+C AVGDPHY+T+DG+ F G C Y L T E+ CS + E N D+ + TK+V I R + G V+K++ L+ + +K +V I ++ V +RV +DG S +++ + G+CG N +DDF T G DV ++ + + KA+ C + + +A+K C +L+ + F C V+ F++DC+ D C K+ S K C I S C G + WR C ++C F E + C +C+ DLP + EGC C G Y+ + CV C C
Sbjct: 849 RCGAVGDPHYQTFDGKRYDFMGKCSYHLLKTQNTSVEAENVACSGAVSESMNFAAPDDP--SCTKAVTI---RFILRDGTPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIRRASSTFLTVEFADGIRVWWDGVSRVYIDAPPSLRGQTQGLCGTFNSNTQDDFLTPEG-DVETAVEPFADKWRTKDTCQ-----FKAETHQGPHPCTLNPEKKAQAEKFCDWILQ--DIFQDCHFL--VEPEQFYEDCLYDTCACKDEMS---KCFCPILSAYGTECMRQGVK-TGWRMSVKECAVKCPLGQVFDECGDGCALSCD-----------DLPSKGSCKRECVEGCRCPHGEYVNEDGECVPKKMCHC 1186 HSP 2 Score: 72.0182 bits (175), Expect = 1.575e-11 Identity = 78/297 (26.26%), Postives = 128/297 (43.10%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYE-LGQKGVLKVNGQLSRVPYEKSDD---------VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKS-GRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFE---GIKWRSQFNCPLQC 1075
CS GD H+ T+DG F G C Y L + D+ F+I +QN G T +KS+ I + E L + ++ P +K D I+K+ F+ ++V +D + +V++ + +K++G+CG+ NG DD +T S G + S L G+++ + HC + ++ C K R A+ CG L ++ F +C V L F++ C+ D C Q CE ++A + I+WRSQ CP+QC
Sbjct: 1337 CSVWGDSHFTTFDGHDFDFQGACDYVLAK-GVFDNGDGFSITIQNVLCG-TMGVTCSKSLEIALTGHAEESLLLSADSAYSTDPNKTPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIPLKLQVKWDEGTRVYVKLGNEWRQKVSGLCGNYNGNSLDDMQTPSMGLETSPM-----LFGHAWKLQP---HC--SAPVAPIDACKKHPERETWAQLKCGALK--SDLFKEC--HAEVPLERFWKRCIFDTCACD------QGGDCECLCTAVAAYADACAQKGINIRWRSQHFCPMQC 1611 HSP 3 Score: 63.929 bits (154), Expect = 5.055e-9 Identity = 85/386 (22.02%), Postives = 131/386 (33.94%), Query Frame = 2
Query: 224 CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSV----------------IIHMFREVYELGQKGVLKVNGQLSRVPYEKS--DDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDF-----KTKSGRDV----SNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCEN------------------HFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHC 1243
C C+++G Y TYD + F G+C Y L++ +F + V + D K V +IH+ R + VL ++ ++PY+ S ++ L + +F+ + S +Y KM G+CGDCNG +D K K+G DV K L+ P HC L +K + F KC VD + C D+C +P Q+ C + A+ C++ G WR CP +C + + C + C+ H T C EGC C G + DG CV + C
Sbjct: 3032 CVCNSLGASKYMTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSMD---DCKKLGQPTPVEGGSCAKSLHILNGDHVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELVLSLPESHVELTASFEDLIFSLGVPSIKYGSKMEGLCGDCNGNAGNDLQPNPAKKKAGVDVIQSWQADEPKLGLVEECLSEDVPKEHC-----------------IPLPPEKDPCLQFYNAELFGKCPLA--VDPIAYVSACQQDIC----KPGNTQQGVCVALAAYAKECNQHGI-CTNWRRPQLCPYECPSDMVYEPCG--CAKNCDTIKALSEFDAVSLKNEAVVHTVKTDEMCLSSERFEGCFCPPGKVMDGGQCVPEIAC 3388 HSP 4 Score: 54.6842 bits (130), Expect = 2.703e-6 Identity = 69/350 (19.71%), Postives = 134/350 (38.29%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRD-DFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVL--LEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIK----WRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+ G + +T+DG V C +TL +F+I ++ G +T ++ +E G +++ + ++P + +++ + +Q +++ +D V+ + K+ G+CG +G + D +++G+ ++ + +++ V C+ G D K +K V L N C + N D + C+ D C NR + C+ + LA+ C+ F+GIK WR+ CP+ CG + TC++ +K C EGC C G ++ C+ C C
Sbjct: 484 CTTWGGINMKTFDGLVFKAPLSCSHTLITDKVSG---TFDIILKACPYGSGYGCAHTLKILWQSVLYTFE-NLNGTMQLTTPIKKLPMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQAGPQMWGKVGGLCGTLDGDPNTDLTSRTGKKLATVK----AFADAWRVEDRSELCQVENSAEMEF--GMDSCEQSKLQKAVSVCERLLANEKLGDCIKPFNYDA--LIRTCMADYCNCANR-EHPESCNCDAIAMLAKECA---FKGIKLEHGWRNLEICPISCGFGRVYQACGPNVEPTCDSDLALPASKGAC-----NEGCFCPEGTVQYKEACITRELCPC 812
BLAST of VWFD domain-containing protein vs. Ensembl Fly
Match: Hml (gene:FBgn0029167 transcript:FBtr0075753) HSP 1 Score: 83.9593 bits (206), Expect = 4.586e-15 Identity = 96/368 (26.09%), Postives = 149/368 (40.49%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTL-----TQHNREDDPCSFNI-EVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKS----------DDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQF-NCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER--------EGCACNRG-YIRDGALCVKPMHCKC 1249
+C AVGDPHY+T+DG+ F G C Y L T E+ CS + E N D+ + TK+V I R + G V+K++ L+ + +K +V I ++ V +RV +DG S +++ + G+CG N +DDF T G DV ++ + + KA+ C + + +A+K C +L+ + F C V+ F++DC+ D C K+ S K C I S C G + WR C ++C F E + C +C+ DLP + EGC C G Y+ + CV C C
Sbjct: 850 RCGAVGDPHYQTFDGKRYDFMGKCSYHLLKTQNTSVEAENVACSGAVSESMNFAAPDDP--SCTKAVTI---RFILRDGTPSVIKLDQGLTTIVNDKPIAKLPKMLGLGEVLIRRASSTFLTVEFADGIRVWWDGVSRVYIDAPPSLRGQTQGLCGTFNSNTQDDFLTPEG-DVETAVEPFADKWRTKDTCQ-----FKAETHQGPHPCTLNPEKKAQAEKFCDWILQ--DIFQDCHFL--VEPEQFYEDCLYDTCACKDEMS---KCFCPILSAYGTECMRQGVK-TGWRMSVKECAVKCPLGQVFDECGDGCALSCD-----------DLPSKGSCKRECVEGCRCPHGEYVNEDGECVPKKMCHC 1187 HSP 2 Score: 72.0182 bits (175), Expect = 1.671e-11 Identity = 78/297 (26.26%), Postives = 128/297 (43.10%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYE-LGQKGVLKVNGQLSRVPYEKSDD---------VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKS-GRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFE---GIKWRSQFNCPLQC 1075
CS GD H+ T+DG F G C Y L + D+ F+I +QN G T +KS+ I + E L + ++ P +K D I+K+ F+ ++V +D + +V++ + +K++G+CG+ NG DD +T S G + S L G+++ + HC + ++ C K R A+ CG L ++ F +C V L F++ C+ D C Q CE ++A + I+WRSQ CP+QC
Sbjct: 1338 CSVWGDSHFTTFDGHDFDFQGACDYVLAK-GVFDNGDGFSITIQNVLCG-TMGVTCSKSLEIALTGHAEESLLLSADSAYSTDPNKTPIKKLRDSVNSKGHNAFHIYKAGVFVVVEVIPLKLQVKWDEGTRVYVKLGNEWRQKVSGLCGNYNGNSLDDMQTPSMGLETSPM-----LFGHAWKLQP---HC--SAPVAPIDACKKHPERETWAQLKCGALK--SDLFKEC--HAEVPLERFWKRCIFDTCACD------QGGDCECLCTAVAAYADACAQKGINIRWRSQHFCPMQC 1612 HSP 3 Score: 63.5438 bits (153), Expect = 5.732e-9 Identity = 85/386 (22.02%), Postives = 131/386 (33.94%), Query Frame = 2
Query: 224 CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSV----------------IIHMFREVYELGQKGVLKVNGQLSRVPYEKS--DDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDF-----KTKSGRDV----SNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCEN------------------HFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHC 1243
C C+++G Y TYD + F G+C Y L++ +F + V + D K V +IH+ R + VL ++ ++PY+ S ++ L + +F+ + S +Y KM G+CGDCNG +D K K+G DV K L+ P HC L +K + F KC VD + C D+C +P Q+ C + A+ C++ G WR CP +C + + C + C+ H T C EGC C G + DG CV + C
Sbjct: 3033 CVCNSLGASKYMTYDRKSFSFNGNCTYLLSRDVVLPGVHTFQVYVSMD---DCKKLGQPTPVEGGSCAKSLHILNGDHVIHVQRVPQKPKSLQVLVDGFEVKKIPYKDSWISLRQVVGKELVLSLPESHVELTASFEDLIFSLGVPSIKYGSKMEGLCGDCNGNAGNDLQPNPAKKKAGVDVIQSWQADEPKLGLVEECLSEDVPKEHC-----------------IPLPPEKDPCLQFYNAELFGKCPLA--VDPIAYVSACQQDIC----KPGNTQQGVCVALAAYAKECNQHGI-CTNWRRPQLCPYECPSDMVYEPCG--CAKNCDTIKALSEFDAVSLKNEAVVHTVKTDEMCLSSERFEGCFCPPGKVMDGGQCVPEIAC 3389 HSP 4 Score: 54.6842 bits (130), Expect = 2.915e-6 Identity = 69/350 (19.71%), Postives = 134/350 (38.29%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRD-DFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVL--LEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIK----WRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+ G + +T+DG V C +TL +F+I ++ G +T ++ +E G +++ + ++P + +++ + +Q +++ +D V+ + K+ G+CG +G + D +++G+ ++ + +++ V C+ G D K +K V L N C + N D + C+ D C NR + C+ + LA+ C+ F+GIK WR+ CP+ CG + TC++ +K C EGC C G ++ C+ C C
Sbjct: 485 CTTWGGINMKTFDGLVFKAPLSCSHTLITDKVSG---TFDIILKACPYGSGYGCAHTLKILWQSVLYTFE-NLNGTMQLTTPIKKLPMPVQVMGMKVMPVAQHVQIDLESVGLKLDWDHRQYVSVQAGPQMWGKVGGLCGTLDGDPNTDLTSRTGKKLATVK----AFADAWRVEDRSELCQVENSAEMEF--GMDSCEQSKLQKAVSVCERLLANEKLGDCIKPFNYDA--LIRTCMADYCNCANR-EHPESCNCDAIAMLAKECA---FKGIKLEHGWRNLEICPISCGFGRVYQACGPNVEPTCDSDLALPASKGAC-----NEGCFCPEGTVQYKEACITRELCPC 813
BLAST of VWFD domain-containing protein vs. Ensembl Zebrafish
Match: zanl (zonadhesin, like [Source:ZFIN;Acc:ZDB-GENE-060131-2]) HSP 1 Score: 161.384 bits (407), Expect = 2.401e-38 Identity = 108/344 (31.40%), Postives = 169/344 (49.13%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKK-HCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
CS GDPHY T+D +V HF G C YTLT+ N F++E QNE+R +NK +Y +SVI+ + LG+ ++VNG P S+ ++IF S KF+ + +RV FDG+ +A V + Y+ + G+CG+ NG +D K ++ N+ +G S+ V C I D I+S K CG++ +PN F C V +F++CV D C C+ A++C++AG I WR+ CP++C +H+ + CP +C++ G++ C + P EGC C+ G++ G CV C C +
Sbjct: 3201 CSVSGDPHYTTFDDKVHHFMGACSYTLTKPCNETSGMPYFSVETQNEHRDNNKKVSYVRSVIVKVHNTTVILGKGRKIQVNGVQVTAPVTLSNGIKIFMSGKFV-VLETNFGLRVRFDGNHHADVTLPSSYNGLLCGLCGNFNGNPNDDNIKLDGKPTDSTNE---LGESWQVPDDRPDCTHGGG----DIECDDKIQSEAQKPTSCGMITDPNGIFKPC--HAVVPPDPYFENCVFDQCGTGGA----AVALCQAIQSYADLCAQAGVP-INWRNNTFCPIKCPVGSHYEHCGSACPASCQDP--GSESTCTE-PCVEGCVCDPGFVLSGDECVPFRECGCTD 3526 HSP 2 Score: 152.14 bits (383), Expect = 1.507e-35 Identity = 104/342 (30.41%), Postives = 157/342 (45.91%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+D + F G+C Y +++ D F + NE R +N + +Y K+V +H + + G ++VNG +P V IF S K VA V V +DG+ + ++V K Y K+ G+CGD NG +DDF+T +G V + + G+S++ C K ++ + C + +CG++L+ PF+ C K V+ +FQ+C+ D+C CE C + G WR+ CPL+C N+HF A C +C+ G PC EGC C+ GYI CVK C C
Sbjct: 680 CIASGDPHYTTFDKRNYDFMGNCSYLMSEPCNSTDVPYFAVYTDNENRYNNLHISYVKAVHVHALGVKVSILKGGTVQVNGTNVNIPLSPVAGVDIFMSGKHYT-VALNFGVTVRYDGNHHMDIKVIKDYEDKLCGLCGDYNGDPQDDFQTPTGELVQSPSD----FGHSWNTDP---DCNK-PEVGPNPGCTDAEQELYEGPAYCGIILDNKGPFAVCHPK--VNPNGYFQNCLFDVCELDGA----HSALCEAIESYVNECQDRGVTIGPWRNSTFCPLKCPPNSHFESCAPVCQPSCKPIPPGQCTGPC-----SEGCVCDPGYILSAGQCVKENTCGC 1001 HSP 3 Score: 149.058 bits (375), Expect = 1.070e-34 Identity = 103/343 (30.03%), Postives = 157/343 (45.77%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDL--PEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+D + F G+C Y +++ D F + NE R +N + +Y K+V +H + + G ++VNG +P V IF S K VA V V +DG+ + ++V K Y K+ G+CGD NG +DDF+T +G V + + G+S++ +C K ++ + C + +CG++L+ PF+ C K V+ +FQ+C+ D+C CE C + G WR+ CPL+C N+H+ A C +C T P P EGC C+ GYI CVK C C
Sbjct: 2436 CIASGDPHYTTFDKRNYDFMGNCSYLMSERCNSTDVPYFAVYTDNENRYNNLHISYVKAVHVHALGVKVSILKGGTVQVNGTNVNIPLSPVAGVDIFMSGKHYT-VALNFGVTVRYDGNHHMDIKVIKDYEDKLCGLCGDYNGDPQDDFQTPTGELVQSPSD----FGHSWNTDP---NCNK-PEVGPNPGCTDAEQELYEGPAYCGIILDNKGPFAVCHPK--VNPNGYFQNCLFDVCELDGA----HSALCEAIESYVNECQDRGVTIGPWRNSTFCPLKCPPNSHYDSCAPVCQPSC------TPVPPSQCTGPCSEGCVCDPGYILSAGQCVKENTCGC 2757 HSP 4 Score: 148.673 bits (374), Expect = 1.496e-34 Identity = 103/343 (30.03%), Postives = 157/343 (45.77%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDL--PEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+D + F G+C Y +++ D F + NE R +N + +Y K+V +H + + G ++VNG +P V IF S K VA V V +DG+ + ++V K Y K+ G+CGD NG +DDF+T +G V + + G+S++ +C K ++ + C + +CG++L+ PF+ C K V+ +FQ+C+ D+C CE C + G WR+ CPL+C N+H+ A C +C T P P EGC C+ GYI CVK C C
Sbjct: 1558 CIASGDPHYTTFDKRRYDFMGNCSYLMSEPCNSTDVPYFAVYTDNENRYNNLHISYVKAVHVHALGVKVSILKGGTVQVNGTNVNIPLSPVAGVDIFMSGKHYT-VALNFGVTVRYDGNHHMDIKVIKDYEDKLCGLCGDYNGDPQDDFQTPTGELVQSPSD----FGHSWNTDP---NCNK-PEVGPNPGCTDAEQELYEGPAYCGIILDNKGPFAVCHPK--VNPNGYFQNCLFDVCELDGA----HSALCEAIESYVNECQDRGVTIGPWRNSTFCPLKCPPNSHYDSCAPVCQPSC------TPIPPSQCTGPCSEGCVCDPGYILSAGQCVKEDTCGC 1879 HSP 5 Score: 138.658 bits (348), Expect = 1.819e-31 Identity = 100/350 (28.57%), Postives = 156/350 (44.57%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDN------KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG+ + G C YTL + + + F+IE +NE RG + K + + + M ++ L VNG +P+ S + + + +++ P ++V +DG+ A + V Y +M G+CGD +G ++ TK + +N N++ G+S+ K D C + ++CG + + N PF C + V+ FFQ CV DMC R Q+V C+ + C AG +WR CPL C N+H+S + CP TC N G C EGC C+ G+I G CV C C++
Sbjct: 1938 CVISGDPHYTTFDGKYYSYMGTCTYTLARTCKNNTRPWFSIEGKNEERGASGVSYLRKLYVTVDGITVTMMKDRTTL-------VNGLRVTLPHSPSPLISLSLAGQYVILTTPF-GLKVQWDGNHYAKISVPSSYYDQMCGLCGDYDGNPNNDFTKPDGNQTNSSNQF---GDSWKTDDDEDATCK-PDPGPQPPCDPVLEGEVSKPENCGKITDTNGPFRDCIKV--VNPLPFFQSCVFDMC----RYQGLQQVLCDQLQAYTDACLSAGAPVHQWREPDFCPLVCPPNSHYSMCVSSCPETCLGINGPPGCSEKCV-----EGCECDPGFILSGNKCVPVKDCGCVD 2264 HSP 6 Score: 135.961 bits (341), Expect = 1.013e-30 Identity = 99/351 (28.21%), Postives = 153/351 (43.59%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDN------KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG+ + G C YTL + + + F+IE +NE RG + K + + + M + L VNG +P+ S + + + +++ P ++V +DG+ A + V Y +M G+CGD +G +DF G V + + L G+S+ +K D C + ++CG + + N PF C + V+ FFQ CV DMC + Q+V C+ + C AG +WR CPL C N+H+S + CP TC N G C EGC C+ G+I CV C C++
Sbjct: 2816 CVVSGDPHYNTFDGKFYSYMGTCTYTLARTCKNNTGPWFSIEGKNEERGASGVSYLRKLYVTVDGITVTMMKNKRTL-------VNGLRVTLPHSPSPLISLSLAGQYVILTTPF-GLKVQWDGNHYAKISVPSSYYDQMCGLCGDYDGNPNNDFTKPDGTQVDSSK----LFGDSWQ-TKEDEDATCKPDPGPQPPCDPVLEGEVSKPENCGKITDTNGPFRDCIKV--VNPLPFFQSCVFDMCHYQG----LQQVLCDQLQAYTDACLSAGAPVHQWREPDFCPLVCPPNSHYSICVSSCPETCLGINGPPGCSEKCV-----EGCECDPGFILSDNKCVPVKDCGCVD 3142 HSP 7 Score: 135.961 bits (341), Expect = 1.021e-30 Identity = 96/369 (26.02%), Postives = 154/369 (41.73%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKA----KDISYH--------------SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
K + F C+ GDPHYRT+D H+ G Y L+Q +N F + +N+ +G + + V + ++ + Q + VN + +PY V I +++ + V FDG S V + Y ++ G+CG+ +G ++ TK V+ N + G+S+ V+ +A K + H + C + L K CG L +P PFS C +D + +DCV D+C + + +RCE ++ A C + G +WR C LQCG N+ + PCP +C + C EGC CN G++ CV C C L
Sbjct: 3966 KPEKFDDCTIAGDPHYRTFDKYNHHYQGAYTYVLSQDNNLPSHLTPFMVRGKNQRQGGISRVSLLREVFVDVYGITVRMQQNKKVLVNEEKVGLPYSPVQGVSIKTKSRYVMLTT-DFGLTVRFDGSSQGVVTLPSVYRTRVLGLCGNYDGRTNNEYTKPDGTVTRDLN---VFGDSWRVTDRSAAALRATSLPKMVHLHKREVEEDPDSGFETTGCTNAQLEDLNGNKQCGALSDPAGPFSAC--HAVIDPEIYMEDCVFDLCAEQGS----EVLRCENYAVYARACQDQGVTLGQWRQDLKCGLQCGANSTYFASMTPCPASCGD--LAAPSECEQTQLVEGCQCNAGFVLSDQDCVPYSQCGCTYL 4322 HSP 8 Score: 135.191 bits (339), Expect = 1.851e-30 Identity = 101/351 (28.77%), Postives = 154/351 (43.87%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDN------KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG+ + G C YTL + + + F+IE +NE RG + K + + + M + L VNG +P+ S + + + +++ P ++V +DG+ A + V Y +M G+CGD +G +DF G V + + L G+S+ +K D C + ++CG + + N PF C + V+ FFQ CV DMC R Q+V C+ + C AG +WR CPL C N+H+S + CP TC N G C EGC C+ G+I G CV C C++
Sbjct: 1060 CIISGDPHYNTFDGKFYSYMGTCTYTLARTCKNNTGPWFSIEGKNEERGVSGVSYLRKLYVTVDGITVTMMKNQRTL-------VNGLRVTLPHSPSSLISLSLAGQYVILTTPF-GLKVQWDGNHYAKISVPSSYYDQMCGLCGDYDGNPNNDFTKPDGTQVDSSK----LFGDSWQ-TKEDEDATCKPDPGPQPPCDPVLEGEVSKPENCGKITDTNGPFRDCIKV--VNPLPFFQSCVFDMC----RYQGLQQVLCDQLQSYTDACLSAGAPVHQWREPDFCPLVCPPNSHYSMCVSSCPETCLGINGPPGCSEKCV-----EGCECDPGFILSGNKCVPVKDCGCVD 1386 HSP 9 Score: 123.635 bits (309), Expect = 6.094e-27 Identity = 100/360 (27.78%), Postives = 149/360 (41.39%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFV----APRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPG----------HHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPER---EGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG + + G C YTL + F I +NE RG + +Y +SV +++ + + G + +N + + PY D+ + KSR F V + V FDG + + V Y K+ G+CG+ NG D K +N ++ + S PG +C ++++ Y + C + K C L+ P F +CV DMC Q C+ A+ C AG I WR+ CPL C N+H+SE PCP TC + F P + LP EGC CN G++ CV C C++
Sbjct: 3586 CHIAGDPHYYTFDGIMHTYMGTCTYTLVEVCNTSMVTPFTIVAKNEERGQPEA-SYVRSVTVYLPTANITISKSGRVLLNERRVKTPY----DINVAKSRVFTSGVNTILDTDFGLIVKFDGVHHVEITVPGDYFNKVCGMCGNYNGDSSDDNLKPNGKPANNSIEFGDSWKAEGDSDPGCQPDPRPDDKPNCDESEEEIYKAQCASTILS--DRFKPCHSLIPP---------------EAFLGNCVYDMCEYNGM----QSTLCDNVEAYAQACHSAGVT-ISWRNSTFCPLPCPPNSHYSECTPPCPPTCADLF-----PIFCPLPPNSCVEGCQCNAGFVLSDGKCVPLSSCGCVD 3913
BLAST of VWFD domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-239b22.1 (si:dkey-239b22.1 [Source:ZFIN;Acc:ZDB-GENE-131119-12]) HSP 1 Score: 150.599 bits (379), Expect = 4.566e-35 Identity = 113/412 (27.43%), Postives = 193/412 (46.84%), Query Frame = 2
Query: 41 SFYQFAKATRYGVCQNTKVE--KEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
SF+ A + +C N+ ++ EPC+ C P Q +C++ + C S GDPHY T+D QV HF G C Y L++ P + IE +NE+RG + + ++T+ V + ++ EV EL G +VNG + P+ ++ +++++S F ++ + V +D S + V Y G+CG+ N DDF + SG +S+ + NS+ V + P H + ++ ++C D HCG+L + PF+ C + + + + ++CV D+C+ + +Q + C+ + A C + G +WR Q C +QC +++HF + CP TC N P LP +E C C+ GYI +CV +C C
Sbjct: 3729 SFWSDATCQQKCICTNSGLQCSPEPCSYSQ-------------ACRP--AAFQYSCQNIPRQTCTVS--GDPHYYTFDNQVFHFQGTCTYVLSEACGIGLP-YYRIEGKNEHRG-STHVSWTRMVRVFVYDEVIELVRGHNYEARVNGSFAATPFSLRNGSIQVYQS-GFSLLISTDFGLLVTYDAFSYVRISVPYDYQNTTCGLCGNYNLQSDDDFHSPSGEILSSDVD----FANSWKVDSDTDPECHNVRCTGLAC-AVCTTDETNRYSDTNHCGILGDVAGPFAAC--QSILAPQTYMENCVYDLCLGEG----YQPILCQALNVYATQCQQQGVHLGQWRQQGFCEIQCPEHSHFEPQGTGCPATCSNPSAPMNCP---LPNQESCICDHGYILSAGVCVPEANCGC 4106 HSP 2 Score: 143.28 bits (360), Expect = 6.944e-33 Identity = 110/412 (26.70%), Postives = 194/412 (47.09%), Query Frame = 2
Query: 41 SFYQFAKATRYGVCQNTKVE--KEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
SF+ A + +C N+ ++ EPC+ ++ R + Q +C++ + C S GDPHY T+D QV HF G C Y L++ P + IE +NE+RG + + ++T+ V + ++ EV EL ++NG + P+ ++ +++++S F ++ + V +D S + V Y G+CG+ N DDF++ SG +S+ + NS+ V + P H + ++ ++C D HCG+L + PF+ C + + + ++CV D+C+ + +Q + C+ + A C + G +WR Q C +QC +++HF + CP TC N P LP +E C C+ GYI +CV +C C
Sbjct: 2273 SFWSDATCQQKCICTNSGLQCSLEPCSY-SQACRAAVF--------------QYSCQNIPRQTCTIS--GDPHYYTFDYQVFHFQGTCTYVLSEACNNGLP-YYRIEGKNEHRG-STHVSWTRMVRVLVYDEVIELVRDHNYEARINGSFAATPFSLRNGSIQVYQS-GFSLAISTDFGLLVTYDAYSYVSISVPYDYQNATCGLCGNYNLRSDDDFRSPSGEILSSDVD----FANSWKVDSDTDPECHNVRCTGLAC-AVCTTDERNRYSDTNHCGILGDVAGPFAAC--HSVLAPQTYIENCVYDLCLGQG----YQPILCQALNVYATQCQQQGVHLGQWRQQGFCEIQCPEHSHFEPQGTGCPATCSNPSAPMNCP---LPNQESCICDPGYILSAGVCVPQANCGC 2650 HSP 3 Score: 112.464 bits (280), Expect = 1.513e-23 Identity = 99/387 (25.58%), Postives = 162/387 (41.86%), Query Frame = 2
Query: 149 VKDNGVCTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTL-TQHNREDDPCSFNIEVQNE-YRGDNKYFTYTKSVII--HMFREVYELGQKGVLKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP-------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ N CTP + C+ ++ +CSA GDPHY+++DG F G CRY L T N + F ++ +NE + G T V + H+ ++ ++++G+ +P S V ++ S +++ +V+ V++ G + + YS G+CG+ NG DDF T SG D+ +++ G S+ V G++C +D A+ C ++ PFS C +VD + ++ +CV D+C++ NR V C A C WR +C + C N+H+ C TC + + C D EGC CN G +R G CV C C
Sbjct: 3061 ITGNVQCTPSSCSEEEVCQVLDGEYGCHPRPQARCSASGDPHYKSFDGTFFDFQGTCRYVLATVCNDTTNLPHFQVDARNEPWHGLTVAITVEVFVNVSGHLVHMSQDMNGHSAVEIDGETRNLPILLDSGRVSVYSSGQYI-YVSTDFGFIVSYGGSWTLNIIIPAEYSNVTCGLCGNFNGQSSDDFMTPSG-DLVRSADQF---GASWKVEDGLSCNDGCGNNCPLCQD-------------QTTARSLCEIIRSSEGPFSFC--HVSVDPQAYYDNCVFDVCLSGNR----NNVLCRSIQTYASACQANNAVIYSWRESASCAMACSNNSHYELCGTDCGHTCASSIDAS---C-DHTCSEGCFCNDGLVRSGGQCVSVEQCGC 3419 HSP 4 Score: 108.997 bits (271), Expect = 1.463e-22 Identity = 94/353 (26.63%), Postives = 150/353 (42.49%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTL-TQHNREDDPCSFNIEVQNE-YRGDNKYFTYTKSVII--HMFREVYELGQKGVLKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP-------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CSA GDPHY+++DG F G CRY L T N F ++ +NE + G T V + H+ ++ ++V+G+ +P S + ++ S +++ +V+ V++ G + + YS G+CG+ NG DDF T SG D+ +++ G S+ + G++C +D A+ C ++ PFS C +VD + ++ DCV D+C++ NR V C A C WR +C + C N+H+ C TC + + C D EGC CN G +R G CV C C
Sbjct: 4551 CSASGDPHYKSFDGTFFDFQGTCRYVLATVCNDTIGLPHFQVDARNEPWHGLTVAITVEVFVNVSGHLVHMSQDMSGHSAVEVDGETRNLPILLDSGGLSVYSSGQYI-YVSTDFGFVVSYGGSWTLNIIIPAEYSGVTCGLCGNFNGQSSDDFMTPSG-DLVRSADQF---GASWKIEDELPCNDGCGNNCPLCQD-------------QTTARSLCEIIRSSEGPFSFC--HVSVDPQAYYDDCVFDVCLSGNR----NNVLCRSIQTYASACQANNAVIYPWRESASCAMACSNNSHYELCGTDCGHTCASSIDAS---C-DHTCSEGCFCNDGLVRSGGQCVSVERCGC 4875 HSP 5 Score: 98.2117 bits (243), Expect = 2.694e-19 Identity = 91/345 (26.38%), Postives = 146/345 (42.32%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ CS Y T+DGQ+ + G C TL + F + V+ RG + + K + + ELG+ +KV+GQ+ +P S +RI+ S + V V D + Y+ + G+CG+ NG + D+F T G + N L S+ HC++ D + G RS + + CG++ + PF++C+R N R DCV + + ++ CE G +C + WR+ NC C +N+H+ CP +C + F + C L +EGC CN G + +G CV PM C C
Sbjct: 2707 YATCSVEDLGSYHTFDGQIFRYAGACGLTLARVMGPSSLPHFVLTVEKIPRGLQDFARFLKFEAGGIQVSI-ELGEGSNVKVDGQMVGLPVSVDSGQIRIYHSSVRGFVLETNFGVTVRADWPHIVRITAPSTYNGTLGGLCGNLNGDIADEFYTPDGVLL----NDTQLFAGSWRDGSLSAHCEEPFD---SWVPGHFQSRS-QFSQQCGIMALLDGPFAECSRTFNPQQR--IADCVQLL----EQTQGAKEALCEALRGYTLLCQQNRIAVEDWRNVTNCEPTCPENSHYEVCGTSCPASCPSLSFPFQ--C-SLQCQEGCQCNDGNVLNGDHCVPPMGCGC 3033 HSP 6 Score: 97.8265 bits (242), Expect = 3.463e-19 Identity = 91/345 (26.38%), Postives = 147/345 (42.61%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ CS Y T+DGQ+ + G C TL + F + V+ RG + + K + + E+G+ +KV+GQ+ +P S +RI+ S + V V D + Y+ + G+CG+ NG + D+F T G + N L S+ HC+ D S+ G+ RS + + CG++ + PF++C+R N R DCV + + ++ CE G +C + G WR+ NC C +N H+ CP +C + F + C L +EGC CN G + +G CV P+ C C
Sbjct: 4163 YATCSVEDLGSYHTFDGQIFRYAGACGLTLARVMGPSSLPHFVLTVEKVPRGLQDFSRFLKFEAGGIQVSI-EMGEGSNVKVDGQMVGLPVSVGSGQIRIYHSSVRGFVLETNFGVTVRADWPHIVRITAPSTYNGTLGGLCGNLNGDIADEFYTPDGVLL----NDTQLFAGSWRDGSLSAHCEDPFD-SWEP--GQFQSRS-QFSQQCGIMALLDGPFAECSRTFNPQQR--IADCVQLL----EQTQGAKEALCEALRGYTLLCQQNGVAVEDWRNVTNCEPTCPENTHYEVCGTSCPASCPSLSFPFQ--C-SLQCQEGCQCNDGNVLNGDHCVPPLGCGC 4489
BLAST of VWFD domain-containing protein vs. Ensembl Zebrafish
Match: si:ch211-39f2.3 (si:ch211-39f2.3 [Source:ZFIN;Acc:ZDB-GENE-131126-52]) HSP 1 Score: 147.132 bits (370), Expect = 4.147e-34 Identity = 111/413 (26.88%), Postives = 197/413 (47.70%), Query Frame = 2
Query: 41 SFYQFAKATRYGVCQNTKVE--KEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR--DDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
SF+ A + +C N+ ++ ++PC+ C P Q +C++ + C S GDPHY T+D QV HF G C Y L++ P + IE +NE+RG + + ++T+ V + ++ +V EL G ++NG + P+ ++ +++++S F ++ + V +D S + V Y G+CG+ N +R DDF++ SG +S+ + NS+ V + P H + ++ ++C D HCG+L + PF+ C + + + ++CV D+C+ + +Q + C+ + A C + G +WR Q C +QC +++HF + CP TC N P LP +E C C+ GYI+ +CV +C C
Sbjct: 255 SFWSDATCRQKCICTNSGLQCSQKPCSYSQ-------------ACRP--AAFQFSCQNIPRQTCTIS--GDPHYYTFDNQVFHFQGTCTYVLSEACGIGLP-YYRIEGKNEHRG-STHVSWTRMVRVFVYNKVIELVRGHNYEARINGSFAATPFSLRNGSIQVYQS-GFSLAISTDFGLLVTYDAYSYVRISVPYDYQNATCGLCGN-NNLRSDDDFRSPSGEILSSDVD----FANSWKVDSDTDPECHNVRCTGLAC-AVCTTDETNRYSDTNHCGILGDVAGPFAAC--HSVLAPQTYMENCVYDLCLGEG----YQPILCQALNVYATQCQQQGVHLGQWRQQGFCEIQCPEHSHFEPQGTGCPATCNNPSAPMNCP---LPNQESCICDPGYIQSAGVCVPQANCGC 632 HSP 2 Score: 146.362 bits (368), Expect = 7.394e-34 Identity = 112/412 (27.18%), Postives = 192/412 (46.60%), Query Frame = 2
Query: 41 SFYQFAKATRYGVCQNTKVE--KEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
SF+ A + +C N+ ++ EPC+ C P Q +C++ + C S GDPHY T+D QV HF G C Y L++ P + IE +NE+RG + + ++T+ V + ++ EV EL G ++NG + P+ + +++++S F ++ + V +D S + V Y G+CG+ N DDF++ SG +S+ + NS+ V + P H + ++ ++C D HCG+L + PF+ C + + + ++CV D+C+ + +Q + C+ + A C + G +WR Q C +QC +++HF + CP TC N P LP +E C C+ GYI +CV +C C
Sbjct: 1711 SFWSDATCRQKCICTNSGLQCSPEPCSYSQ-------------ACRP--AAFQYSCQNIPRQTCTVS--GDPHYYTFDNQVFHFQGTCTYVLSEACGIGLP-YYRIEGKNEHRG-STHVSWTRMVRVFVYDEVIELVRGHNYEARINGSFAATPFSLHNGSIQVYQS-GFSLLISTDFGLLVTYDAYSYVRISVPYDYQNVTCGLCGNYNLQSDDDFRSPSGEILSSDVD----FANSWKVDSDTDPECHNVRCTGLAC-AVCTTDERNRYSDTNHCGILGDVAGPFAAC--HSVLAPQTYMENCVYDLCLGEG----YQPILCQALNVYATQCQQQGVHLGQWRQQGFCEIQCPEHSHFEPQGTGCPATCSNPSAPMNCP---LPNQESCICDYGYILSAGVCVPQANCGC 2088 HSP 3 Score: 107.457 bits (267), Expect = 4.378e-22 Identity = 99/388 (25.52%), Postives = 161/388 (41.49%), Query Frame = 2
Query: 149 VKDNGVCTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTL-TQHNREDDPCSFNIEVQNE-YRGDNKYFTYTKSVII--HMFREVYELGQKGVLKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP-------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+ N CTP + + C+ ++ +CSA GDPHY ++D F G CRY L T N F ++ +NE + G T V + H+ +L ++V+G+ +P S + ++ S +++ +V+ V++ G + + YS G+CG+ NG DDF T SG D+ +++ G S+ + G++C +D A+ C ++ PFS C +VD + ++ DCV D+C++ NR V C A C WR +C + C N+H+ C TC + + C D EGC CN G +R G CV C C+
Sbjct: 2499 ITGNVQCTPSSCREEEVCQVLDGEYGCHPRPQARCSASGDPHYMSFDRTFFDFQGTCRYVLATVCNDTIGLPHFQVDARNEPWHGLTVAITVEVFVNVSGHLVHMSQDLNGHSAVEVDGETRNLPILLNSGGLSVYSSGQYI-YVSTDFGFIVSYGGSWTLNIIIPAEYSGVTCGLCGNFNGQSSDDFMTPSG-DLVRSADQF---GASWKIEDGLPCNDGCGNNCPLCQD-------------QTTARSLCEIIRSNEGPFSFC--HVSVDPQAYYDDCVFDVCLSGNR----NNVLCRSIQTYASACQANNAVIYPWRESASCAMSCSNNSHYELCGTDCGHTCASSIDAS---C-DHTCSEGCFCNDGLVRSGGQCVSVEQCGCL 2858 HSP 4 Score: 107.071 bits (266), Expect = 4.841e-22 Identity = 101/387 (26.10%), Postives = 159/387 (41.09%), Query Frame = 2
Query: 149 VKDNGVCTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTL-TQHNREDDPCSFNIEVQNE-YRGDNKYFTYTKSVII--HMFREVYELGQKGVLKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP-------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ N CTP + + C+ ++ +CSA GDPHY ++D F G CRY L T N F ++ +NE + G T V + H+ +L ++V+G+ +P S V ++ S +++ +V+ V++ G + + YS G+CG+ NG DDF T SG D+ +++ G S+ V G++C +D A+ C ++ PFS C +VD + ++ DCV D+C++ NR V C A C WR +C + C N+H+ C TC + + C D EGC CN G R G CV C C
Sbjct: 1043 ITGNVQCTPASCREEEVCQVLDGEYGCHPRPQARCSASGDPHYMSFDRTFFDFQGTCRYVLATVCNDTIGLPHFQVDARNEPWHGLTVAITVEVFVNVSGHLVHMSQDLNGHSAVEVDGETRNLPVLLNSGRVSVYSSGQYI-YVSTDFGFVVSYGGSWTLNIIIPAEYSGVTCGLCGNFNGQSSDDFMTPSG-DLVRSADQF---GASWKVEDGLSCNDGCGNNCPLCQD-------------QTTARSLCEIIRSSEGPFSFC--HVSVDPQAYYDDCVFDVCLSGNR----NNVLCRSIQTYASACQANNAVIYPWRESASCAMACSNNSHYELCGTDCGHTCASSIDAS---C-DHTCSEGCFCNDGLARSGGQCVSVEQCGC 1401 HSP 5 Score: 100.523 bits (249), Expect = 5.154e-20 Identity = 102/395 (25.82%), Postives = 163/395 (41.27%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDE 1399
+ CS Y T+DGQ+ + G C TL + + F + V+ RG + + K + + E+G+ +KV+GQ+ +P S +RI+ S + V V D + Y+ + G+CG+ NG + D+F T G + N L S+ HC+ D + G+ RS + + CG++ + PF++C+R N R DCV + + ++ CE G +C + WR+ NC C +N H+ CP +C + F + C L +EGC CN G + +G CV PM C C R + R W QG C+ L +C G + T C +E
Sbjct: 2145 YATCSVEDLGSYHTFDGQIFRYAGACGLTLARVMGQCSLPHFVLTVEKVPRGFQNFSRFLKFEAGGIQVSI-EMGEGSNVKVDGQMVGLPVSVGSGQIRIYHSSVRGFVLETNFGVTVRADWPHIVRITAPSTYNGTLGGLCGNLNGNIADEFYTPDGVLL----NDTQLFAGSWRDGSLSAHCEDPFD---SWVPGQFQSRS-QFSQQCGIMAMLDGPFAECSRTFNPQQR--IADCVQLL----EQTQGAKEALCEALRGYTLLCQQNRIAVEDWRNVTNCEPTCPENTHYEVCGTSCPASCPSLSFPFQ--C-SLQCQEGCQCNDGNVLNGDHCVPPMGCGC--HYSGRYYEARQRFWHGQG-CQFLC-----VCDGITGNVQCTPSSCREE 2513 HSP 6 Score: 99.3673 bits (246), Expect = 1.087e-19 Identity = 100/395 (25.32%), Postives = 161/395 (40.76%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDE 1399
+ CS Y T+DGQ+ + G C TL + + F + V+ RG + + K + + E+G+ +KV+GQ+ +P S +RI+ S + V V D + Y+ + G+CG+ NG + D+F T G + N L S+ HC++ ++S + + + CG++ + PF++C+R N R DCV + + ++ CE G +C + G WR+ NC C N H+ CP +C + F + C L +EGC CN G + G CV PM C C R + R W QG C+ L +C G + T C +E
Sbjct: 689 YATCSVEDLGSYHTFDGQIFRYAGACGLTLARVMGQCSLPHFVLTVEKVPRGFQNFSRFLKFEAGGIQVSI-EMGEGSNVKVDGQMVGLPVSVGSGQIRIYHSSVRGFVLETNFGVTVRADWPHIVRITAPSTYNGTLGGLCGNLNGNIADEFYTPDGVLL----NDTQLFAGSWRDGSLSAHCEEP----FNSWEPGHFQSRSQFSQQCGIMALLDGPFAECSRTFNPQQR--IADCVQLL----EQTQGAKEALCEALRGYTLLCQQNGVAVEDWRNVTNCEPICPNNTHYEVCGTSCPASCPSLSFPFQ--C-SLQCQEGCQCNDGNVLTGDHCVPPMGCGC--HYSGRYYQARQRFWHGQG-CQFLC-----VCDGITGNVQCTPASCREE 1057
BLAST of VWFD domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-65b12.6 (si:dkey-65b12.6 [Source:ZFIN;Acc:ZDB-GENE-060526-329]) HSP 1 Score: 136.732 bits (343), Expect = 4.852e-31 Identity = 99/350 (28.29%), Postives = 152/350 (43.43%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ C GDPH+RT+DG+ F G C Y L++ DP F + V+NE RG N YTKSV + ++ L ++ G +KVN ++P+E D + IF S F + + + F+ DS+ + + Y + G+CG+ N + D+F T + + S+ G S+ V PG C A + C K C + + PF C K N +L F++DCV DMC+ + C + C A WR+ CP C ++H+ A CP+TC + C EGC C++G++ CV C C
Sbjct: 797 YSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYF-GMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATA----SIFGTSWKVKDDPG--CSDACQGKACASCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNL--FYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGTVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSG--LTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGC 1131 HSP 2 Score: 132.494 bits (332), Expect = 8.192e-30 Identity = 98/347 (28.24%), Postives = 150/347 (43.23%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C GDPH+RT+DG+ F G C Y L++ D F + V+NE RG N YTKSV + ++ L ++ G +KVN ++P+E D + IF S F + + + F+ DS+ + + Y + G+CG+ N + D+F T + + S+ G S+ V PG C A + C K C + + PF C K N +L F++DCV DMC+ + C + C A WR+ CP C ++H+ A CP+TC + C EGC C++G++ CV C C
Sbjct: 1197 CQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADLTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYF-GMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATA----SIFGTSWKVKDDPG--CSDACQGKACASCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNL--FYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGAVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSG--LTEPKSCKGTLCTEGCTCDKGFVLSDGECVAAQQCGC 1528 HSP 3 Score: 124.79 bits (312), Expect = 2.127e-27 Identity = 94/362 (25.97%), Postives = 156/362 (43.09%), Query Frame = 2
Query: 197 NCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKG---VLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLK-----AKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C K C C GDPH+RT+DG+ F G C Y L++ DP F + V+NE RG N YTKSV + ++ L + G ++V+ + +P + + V +++ +D S A +E+ + + G+CG+ NG DDF G S++ + ++ + C+ CG + ++ K A+ C +L+ PFS C K + + +F DCV D+ ++ + + ++ + S C G I WR+ CPL C KN+H+ + C TC + + P +EGC C+ G++ DG C C C
Sbjct: 287 GCFPDGKAVCTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVAKIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVD----FVEAWVSASDKMMCQTG--------CGANCLKPDKDKQTTAETACSLLITEKGPFSSCYDK--IPPQKYFDDCVKDVAQATDKTAHCRHIQNYVAS-----CQAIGISIIVWRNTTFCPLTCFKNSHYELCTDTCSSTCASLTKSQRCPLC----QEGCQCDDGFLFDGGECKALQDCGC 625 HSP 4 Score: 73.9442 bits (180), Expect = 4.473e-12 Identity = 64/248 (25.81%), Postives = 94/248 (37.90%), Query Frame = 2
Query: 512 RIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
IF+S F V + + F+ DS+ + + Y + G+CG+ N + DDF T S+ G S+ V PG C A C K C + + PF C K V+ F++DCV DMC+ + C + C A WR+ CP C N+H+ A C +TC H + C E C C+ G++ +CV C C
Sbjct: 2 SIFRSGYF-GVVKTDFDLTMKFNWDSHVALTLPSTYYGVVGGLCGNWNDNINDDFLTPD----KTLGATASIFGTSWKVQDDPG--CSDACQGKACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSK--VNPNQFYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGAVESWRTDSFCPASCMDNSHYEVCAAGCSQTC--HGLTEPKACVGTSCVESCICDEGFVLSDGVCVSMEQCGC 234
BLAST of VWFD domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-65b12.6 (si:dkey-65b12.6 [Source:ZFIN;Acc:ZDB-GENE-060526-329]) HSP 1 Score: 135.191 bits (339), Expect = 1.849e-30 Identity = 110/382 (28.80%), Postives = 161/382 (42.15%), Query Frame = 2
Query: 146 YVKDNGVCTPFRTKTQVNCESKR--KD-----FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
Y K N C P + + C + KD + C GDPH+RT+DG+ F G C Y L++ DP F + V+NE RG N YTKSV + ++ L ++ G +KVN ++P+E D + IF S F + + + F+ DS+ + + Y + G+CG+ N + D+F T + + S+ G S+ V PG C A + C K C + + PF C K N +L F++DCV DMC+ + C + C A WR+ C C N H+ C TC N K LP EGC CN G++R G C+ C C
Sbjct: 1593 YSKRNVECAPAKCMNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYF-GMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATA----SIFGTSWKVKDDPG--CSDACQGKACASCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNL--FYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGTVESWRTDSFCQTYCPVNMHYEACGTACAPTCANRDGPEKCA---LPCVEGCQCNAGFVRSGDECIPVKQCGC 1958 HSP 2 Score: 134.42 bits (337), Expect = 2.836e-30 Identity = 106/375 (28.27%), Postives = 158/375 (42.13%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKR--KD-----FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKG--VLKVNGQLSRVPYEKSDDV-RIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CTP + K C+++ KD + C A GDPH+RT+DG+ F G C Y L++ DP F + V+NE RG N YTK+V + ++ L + +KVN +P+E+ D + IF+S F V + + F+ DS+ + + Y + G+CG+ N + DDF T S+ G S+ V PG C A C K C + + PF C K V+ F++DCV DMC+ + C + C A WR+ CP C N+H+ A C +TC H + C E C C+ G++ +CV C C
Sbjct: 789 CTPTKCKKSQMCDTRNGVKDCYPLSYSTCQAAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKTVSLKVYNYTIVLSKDDPFTVKVNNLFVNLPFEQKDGLFSIFRSGYF-GVVKTDFDLTMKFNWDSHVALTLPSTYYGVVGGLCGNWNDNINDDFLTPD----KTLGATASIFGTSWKVQDDPG--CSDACQGKACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSK--VNPNQFYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGAVESWRTDSFCPASCMDNSHYEVCAAGCSQTC--HGLTEPKACVGTSCVESCICDEGFVLSDGVCVSMEQCGC 1148 HSP 3 Score: 132.109 bits (331), Expect = 1.327e-29 Identity = 98/350 (28.00%), Postives = 151/350 (43.14%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ C GDPH+RT+DG+ F G C Y L++ D F + V+NE RG N YTKSV + ++ L ++ G +KVN ++P+E D + IF S F + + + F+ DS+ + + Y + G+CG+ N + D+F T + + S+ G S+ V PG C A + C K C + + PF C K N +L F++DCV DMC+ + C + C A WR+ CP C ++H+ A CP+TC + C EGC C++G++ CV C C
Sbjct: 2017 YSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADLTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYF-GMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATA----SIFGTSWKVKDDPG--CSDACQGKACASCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNL--FYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGAVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSG--LTEPKSCKGTLCTEGCTCDKGFVLSDGECVAAQQCGC 2351 HSP 4 Score: 130.183 bits (326), Expect = 5.907e-29 Identity = 92/344 (26.74%), Postives = 152/344 (44.19%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNR-EDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELG-QKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGV-RDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGI-KWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C AVGDPH++T+DG++ F G C Y + + + F+I +N +RG + Y +SV + ++ +G QKGV++ +G+ + +P R ++ + V +D + ++ Y + + G+CG+ NG RD++ G +S+ + ++ V C + S C K + +CGV+ + + PF C VD R + +CV D+C+N + C + C AG + WR+ NCPL C N H+ C +C + K LP EGC CN G++R GA CV C C
Sbjct: 427 CHAVGDPHFKTFDGKLFDFQGTCTYVMVNSTKTQKGLIPFSILTKNNHRGSTR-VAYVRSVSVLVYTHTIVVGSQKGVVEFDGENTYLPLSIDGGKIKVNQRGLNVIISTDFGLEVKYDWNMMLYITAPSSYFQTVGGLCGNYNGDRRDEYIDPKGNTLSSIID----FAKTWKVPDNDLFCNDDCNGQCPS-CTVSLQEEYKKESNCGVIAKSDGPFVLC--HNTVDPRMYVDNCVYDVCINNGI----RNFLCNNIQSYVDACMSAGIKITGNWRTLANCPLSCPVNMHYEFCGTACAASCADRSAPDK---CTLPCVEGCHCNTGFVRSGAECVPMNKCGC 755 HSP 5 Score: 91.6633 bits (226), Expect = 2.312e-17 Identity = 81/350 (23.14%), Postives = 147/350 (42.00%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNR-EDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLK-----AKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CS G Y+++DG+ GDC Y L + + +D SF++ ++ + + +T+ V I + + L G ++V+ + +P + +++++S + V +++ +D S A +E+ + + G+CG+ NG DDF G S+ ++ C+ CG + ++ K A+ C +L+ PFS C K + + +F DCV D+ ++ + C C G I WR+ CP+ C N+H+ + C TC + K P P +EGC C+ G++ DG C C C
Sbjct: 2413 CSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQ----SSEMVFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINI-VVETDFGLKLTYDTVSVAKIEIPSTFKNAVRGLCGNYNGNSADDFLLPDGIQTSSVE----YFAEAWVSPSDKMMCQTG--------CGANCLKPDKDKQTTAETACSLLITEKGPFSSCYDK--IPPQKYFDDCVKDVAQATDKTAH-----CRHMQNYVASCQAIGISIIVWRNITFCPIMCLANSHYELCTDTCSSTCASLTNSQKCP----PCQEGCQCDDGFLFDGGECKAFQDCGC 2734 HSP 6 Score: 91.6633 bits (226), Expect = 2.734e-17 Identity = 83/353 (23.51%), Postives = 144/353 (40.79%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTL--TQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEP-------NNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CS G Y+++DG+ GDC Y L T + +DD F++ ++ + + +T+ V + + L G ++V + +P + +++++S + V +++ +D S A +E+ + + G+CG+ NG DDF G S++ + ++ + G + ICG + A K EP PF C K V+ F++DCV DMC+ + C + C A WR+ CPL C KN+H+ + C TC + + P +EGC C+ G++ DG C C C
Sbjct: 1210 CSVSGFGFYQSFDGRSFSVQGDCEYRLVETALDSDDDLSFFSVLIKQQ----SSEMVFTRRVELQIEESTITLLPGHIWEVQVGKVKTNLPVTVGEGLIQVYQSGINI-VVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVD----FVEAWVSASAGVFTCVPMECKEEEICGN--VECAPANKLLHAQTEPCSKITDKQGPFKGCHSK--VNPNQFYEDCVYDMCMYGGHST----ALCSALTAYTAACQHALGAVESWRTDSFCPLTCFKNSHYELCTDTCSSTCASLTKSQRCPLC----QEGCQCDDGFLFDGGECKALQDCGC 1541
BLAST of VWFD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000000752.1 (Fc fragment of IgG binding protein [Source:NCBI gene;Acc:100379885]) HSP 1 Score: 161.384 bits (407), Expect = 3.416e-38 Identity = 123/399 (30.83%), Postives = 178/399 (44.61%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKRK-------DFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKE 1321
VCTP K C F CSA GDPHY T+DG+ F G C Y L D + F ++VQN RG NK +YTK V + ++ V L + V+G + +P Y+ +D V + S + + V +D S V V Y+ +NG+CG+ N DD K+G N G+S+ V + PG + S +C + + K++K+CG++ + N PFS+C+ +D FF DCV D C + PS + C C AG + +WRS CPL C N+H+ N CP TC + C P +E C+C+ G+I G CV C C+ +S+E + GQC E
Sbjct: 2052 VCTPTSCKASEKCLVVNGVRGCHPISFSTCSAYGDPHYTTFDGRRFDFMGTCVYQLVGVTSSDASLTRFTVKVQNNNRG-NKAVSYTKVVTVEVYNMVLTLSMDFPRRILVDGVATALPWYDGTDRVSAYISGN-QGIIKTDFDLTVVYDWSSYVAVTVPSTYTNAVNGLCGNNNKNPNDDLTMKNGNAAGNAVQ----FGDSWKVGEVPGC---TPECTSNCPLCSEAQKQDYKSEKYCGIITKANGPFSQCSSV--IDPTPFFNDCVFDACQYRGHPSSF----CNAIGLYVSACQAAGVQIQEWRSATFCPLSCPLNSHYELCGNGCPVTCSG--LASPTGCV-APCKESCSCDNGFILSGHKCVPIASCGCVYQNKYYQSNE---VFYPNGQCSE 2429 HSP 2 Score: 150.599 bits (379), Expect = 5.564e-35 Identity = 102/352 (28.98%), Postives = 170/352 (48.30%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELG--QKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C AVGDPH+RT+DG+ F G C YT+ + + D FNIE +NE RG+ + Y V + ++ L + G ++VN Q R+P +D VR+++S + + S++V +D +S V +S + + ++G+CG+ NG DD T +G N + G S+ V C +H+ C D + +++ CG+L + + PF +C G+VD + + +CV D+C+N +++ C+ A+ C + +WR CP+QC +N+ + + CP TC + T C + EGC C GY+ D C+ C CI
Sbjct: 499 CWAVGDPHFRTFDGRFYDFQGTCTYTIAKTSGSDSSLPVFNIEAKNENRGNTR-VAYVSFVTVQVYGFTMSLVRYENGFVRVNDQRQRLPMNLNDGQVRLYQSGSMV-VIETDFSMKVYYDWNSILKVSISSSFYESVSGMCGNYNGNPGDDLVTPAGTQAPNLVD----FGKSWKVEDGDRFC-------WHNCNGECKTCSLDLQKQYASEQTCGLLSKADGPFRQC--HGSVDPKVYVDNCVYDLCMNGGS----KQILCQSIKSYADACQRNKIQIAEWRQPSACPMQCPENSQYKLCSKGCPSTCNDD--ATPSTCSE-SCVEGCECKDGYVLDEGKCIPKSSCGCI 828 HSP 3 Score: 143.28 bits (360), Expect = 9.763e-33 Identity = 107/346 (30.92%), Postives = 163/346 (47.11%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ--KGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHF--FGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+A GDPHY ++DG F G C Y L + + F + VQNE RG +K YT +V + + + + K + VN L+ +PY + + F + +RV ++ DS V++ Y+ + G+CG+ +G +++ T V+ K L GNS+ V PG + + D S + + +R +K+ CG+L++ + PF C K VD + F+DCV D C R Q + C++ +G A C AG WRS CP+ CGKN+H+ A+ CP TC G C EGC C+ G+I G CV C C
Sbjct: 889 CTASGDPHYVSFDGVRYDFQGTCIYQLAGLCKKTEGLVDFTVNVQNENRG-SKVVAYTSAVNVTLCNLQIGITRQYKDRILVNQVLTNLPYSVENGKLSIYKQGFNAILQTSFGLRVVYNWDSYVEVKIPSTYAGAVCGLCGNYDGDKNNEFTMKNNQVATKP---LLFGNSWKVQNVPGCYEEDKGDCSNLA---ELELRHRASKESCGMLIDKSGPFRDCHAK--VDPQGAFKDCVYDSCFYAGR----QDILCKVIAGYAAACQRAGLNIEPWRSAKFCPV-CGKNSHYEVCASACPSTCLALAPPMGCSGEC-----SEGCECDDGFILSGGDCVPISQCGC 1215 HSP 4 Score: 140.969 bits (354), Expect = 4.916e-32 Identity = 98/350 (28.00%), Postives = 148/350 (42.29%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDD-PCSFNIEVQNEYRGD-NKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHC-KKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRP------CYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+C A GDPHY ++DG F G C YTL + +D F++ V+NE G+ N T V ++ + E G K KV+G++ ++P DD + + ++V +D + V V Y KM G+CG+ NG + D + V N++ G ++ VS G C D + +C ++ K CG++ P+ PF C K + +F C D C + + C+ VC G WR+ CPL C N+H+ C RTC+ G P C+ EGC CN G++ DG CV C C
Sbjct: 2468 RCVAQGDPHYISFDGLTFDFQGTCTYTLAKVVDDDSRLVKFSVGVENESYGNGNVAVTRLVVVSVYGYSIAIERGMKWNAKVDGEILKLPLSLDDDSIVINQEGNNIVIQTDFGLKVLYDAVYHVVVNVPSSYRGKMGGLCGNFNGDKSDEFQLPNKQVVKNVNQF---GAAWKVSIAGAKCYDDCGDKCF--VCDPPKLQPFKGTASCGMITNPSGPFRACHSK--ISPTEYFDHCTYDSCAAEGK----DDFLCKSLQAYTAVCQTVGVAIENWRTASFCPLSCPANSHYEL----CTRTCDQTCTGISSPTKCTTRCF-----EGCECNAGFVSDGEKCVSMDKCGC 2797 HSP 5 Score: 129.798 bits (325), Expect = 9.865e-29 Identity = 103/368 (27.99%), Postives = 156/368 (42.39%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKY-FTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK--AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI------NLCVDRESSEKC 1288
F CSA GDPHY + DG F G C YTLT+ + F + V+NE GD K T S+ ++ + + + +G + VN L +P D VR ++ + V+V++D + V V Y ++ G+CG+ N R D+F+ R ++ + G+S+ V PG C + + + C + +CG L + + P S C G ++ +F +C+ D+C C VC AG WRS CPL C N+ + A+ C TC TK P EGC C+ G+ DG CV +C C N+ V + SE C
Sbjct: 1273 FGTCSAAGDPHYMSLDGLAFDFQGTCTYTLTKSITSNANLVPFAVNVKNEKYGDGKVAVTKLVSLEVYGYTLILQYNTQGRILVNNVLYNLPLTLEDGKVRAYQ-HGIRTNIETDFGVKVSYDLVYHVIVTVPGNYKGQVGGLCGNFNDDRKDEFQLPDKRLTADA----TTFGSSWKVQIPGVSCDEGCGGNGNPCPACDAKKKEIFQTDNYCGFLKKKDGPLSAC--YGTINPDTYFNNCLFDVCAGAGD----GDTLCRSIQSYVAVCQAAGIAIQSWRSDSFCPLTCPANSKYKVCADVCSTTCAGVTDFTKCP---TTCSEGCECDDGFFFDGKNCVSMDNCGCFEDGRYYNVIVSNDCSEVC 1626 HSP 6 Score: 111.309 bits (277), Expect = 4.034e-23 Identity = 100/392 (25.51%), Postives = 167/392 (42.60%), Query Frame = 2
Query: 95 VEKEPCTNGTRNIRITTYVKD-NGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDP-CSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS--ICGKDWIRSLKAKKHCGVLLEP-NNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
V K+PC + + T ++D N VC P T T C A GDPHY T+DG F G C Y L+++ D F IE +N+ RG ++ Y ++V I+M+ + G+ G +++N ++ +P D V ++V ++ + V +S Y G+CG+ N +D ++ +K + I + K D + C + ++ CG++ + N PF +C K N D NFF +C+ D+C+N ++ C+ + A C + G + WR+ C L C +N+H+ N CP +C + ++ C D E C CN G++ CV C C
Sbjct: 1657 VNKDPCKSMKCRTKETCKIQDGNAVCVPDYTGT-------------CWAWGDPHYHTFDGYNYDFQGTCTYILSKYIGNDPGLVPFTIEEKNDNRG-SQTVAYVRTVNIYMYGYKVSIVKGEFGKVRINDVVANLPVALLDGKISVSISGANAVVKTDFGLQVTYEYNWYVVVTLSSSYYGATGGLCGNFNQNSND------EMIAADGSKVTAIVDWAKTWKVNDRDPFCWDFCRGNCPTCDDSKKSTYGGEQFCGLISKAANGPFRECHPKINPD--NFFDNCLYDVCINGGA----KQFLCQALTAYANTCRKQGAKIYDWRTPSGCVLPCPENSHYEFCGNACPASCSDRTAPSR--CTDA-CVETCQCNDGFVLSADKCVPVKSCGC 2019 HSP 7 Score: 98.9821 bits (245), Expect = 2.031e-19 Identity = 87/346 (25.14%), Postives = 138/346 (39.88%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAF--VEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+ CS +GD +Y +DGQ F G C + + E+ E G + + T +VI+ ++R + + +L V +++ +++F+S + + V+FD SN F V V Y+ N +CG C D PG A CG S ++ +CG++ + PF C + V+ ++FQ+C+ +MC R + Q C+ G C EAG WR++ C C NA + + CP TC PC LP +EGC CN GY + G +C P C C+
Sbjct: 3242 YLSCSVLGDLNYTAFDGQQYKFQGSCLAKMAGLCSSLPGLEY-FELYLEKEGKSNF---TTAVILKIYRTTVTISGYPQKTYSVRLPFVLHDRR--LQVFRSGLNAIVLQIDFGLVVSFD-SSNGFLLVRVPDSYT---NAVCGACAAPSDIV--------------------------PGVQACGASCTGDCIECGAAEKESYRSFNNCGIITDLQGPFRDCRTR--VNTESYFQNCLGNMC----RHNGSQVALCQSLGGFVAACQEAGGTVYSWRTEELCKPSCPANAQYELCVSSCPDTCNGSL---PLPC-PLPCKEGCPCNPGYTQSGDMCALPEDCGCL 3541 HSP 8 Score: 97.0561 bits (240), Expect = 9.483e-19 Identity = 94/401 (23.44%), Postives = 166/401 (41.40%), Query Frame = 2
Query: 200 CESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ--KGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAF-----VEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI---------NLCVDRESSEKCR-KWKQQGQCKELSEAMNIIC 1348
C + + C S + HYR++DG + +C Y + + + D+ + F + V + +N K V+++++ L +G+L VNG P + + + VR F + +++ YS KM G+CG+ N +D ++++ +K+ +S+PG + + + + + + ++C VL++P PF C +V +F++DC++ N N + K C G A C AG WR++ CP C N++++ +PC TC + F T PC + EGC CN G+ DG CV C C + +D + + C Q QC+ LS IC
Sbjct: 3591 CSAPKSPICWVS--NNLHYRSFDGTTFNGNVNCSYVMAKVCKMDNLTTEFELHVTGDLD-ENSGMYQLKEVLLNVYGYTLSLSTETQGIL-VNGTAQYNP------IDLENGKISAISHISSILVRTDFGLSVSLSYSLLSIQIPSNYSGKMCGLCGNANQNAND-----DQNINATLSKW--------LSRPGQGMCDSPVQDFSNDFPNETAQFSNSSQYCAVLVDPEGPFMSCLV--SVSPVSFYEDCLM----NFNMGGGFNKYICSTIEGYARTCQLAGSTVYPWRNESFCPAGCPANSNYTICKDPCSPTCIDPFRYT--PCQSMCS-EGCECNSGFYEDGGRCVPTEACGCYVQGYYYPQGYVGIDEDCQQNCSCPQFNQWQCEPLSCPSESIC 3959 HSP 9 Score: 63.5438 bits (153), Expect = 1.101e-8 Identity = 83/348 (23.85%), Postives = 125/348 (35.92%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDG-QVIHFYGDCRYTLTQHNR---EDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCV-NKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTC---ENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A G +YRT+ G DC L + ED P F++E E + TY +V EV E G +K+NG+L +P D K V+ +RV +++ RYS ++ G C D N YS I S G C A ++ CG+ + ++C ++ + + F C ++ + + F C+ +C + NR C A C+ G WR+ C LQC +H+ + PR C E +F+ PC E C C G CV C C
Sbjct: 2882 CMAWGSTYYRTFGGRHTFQPAQDCATLLIAYPGVMGEDWP--FSVERSPEEEFSLTFRTYGDTV------EVTE-DMSGRIKLNGELIYLPATLFDGRLTIKQWGLSTEVSYSFGLRVTIGVRGLLHLQLHNRYSTQVFGACADAGS-------------QGPLNAYSWIS-----SANGELCDPASPVTARD-CGR---MNSSVAQNCSLMAD-HAIFQACHKQ--ICPKPFIDSCLHALCTESGNR-------TCSALEAYALACAMEGVNLTTWRTIAKCDLQCPPQSHYETCPSAPPRACLVSEGYFY---SPCDGNNCIETCVCEEGLQLSMGACVPSNQCGC 3185 HSP 10 Score: 54.6842 bits (130), Expect = 5.010e-6 Identity = 57/257 (22.18%), Postives = 92/257 (35.80%), Query Frame = 2
Query: 563 VRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKA-KDISYHSICGKDWIRSLKA----------KKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC-INLCVDRESSEKCRKW 1297
+ V F G F+ + Y +N CG C GV T G + + + + V+ A ++ S + + +L + C +LL+ + PF C +D ++ C+ C + C+ C + WR+ CP C N H+S +PC TC GT +L EGC CN G R+G C+ C C N + + +C +W
Sbjct: 3992 LTVLFKGGEYLFIMLPAGY---LNSTCGLCAGVNMTMVTTPGAVATAAATPMTPVAAATLVTPVAAATSSAIVAVATPSEGNQSFSDTLSSWNCSDSDHPGASLCMILLDNDGPFGACHEV--LDPYLYYDACLSSQCQKGGNIAG----VCQSLQNYTLSCQQQNQTIEPWRNDSFCPFACPMNKHYSICVDPCGETCTAP-NGTSS--CNLTCIEGCECNVGLYREGDKCIPIEACGCNANGTYFKVGALRCERW 4236
BLAST of VWFD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000000563.1 (Fc fragment of IgG binding protein [Source:NCBI gene;Acc:100379885]) HSP 1 Score: 160.999 bits (406), Expect = 3.857e-38 Identity = 123/399 (30.83%), Postives = 178/399 (44.61%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKRK-------DFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKE 1321
VCTP K C F CSA GDPHY T+DG+ F G C Y L D + F ++VQN RG NK +YTK V + ++ V L + V+G + +P Y+ +D V + S + + V +D S V V Y+ +NG+CG+ N DD K+G N G+S+ V + PG + S +C + + K++K+CG++ + N PFS+C+ +D FF DCV D C + PS + C C AG + +WRS CPL C N+H+ N CP TC + C P +E C+C+ G+I G CV C C+ +S+E + GQC E
Sbjct: 1569 VCTPTSCKASEKCLVVNGVRGCHPISFSTCSAYGDPHYTTFDGRRFDFMGTCVYQLVGVTSSDASLTRFTVKVQNNNRG-NKAVSYTKVVTVEVYNMVLTLSMDFPRRILVDGVATALPWYDGTDRVSAYISGN-QGIIKTDFDLTVVYDWSSYVAVTVPSTYTNAVNGLCGNNNKNPNDDLTMKNGNAAGNAVQ----FGDSWKVGEVPGC---TPECTSNCPLCSEAQKQDYKSEKYCGIITKANGPFSQCSSV--IDPTPFFNDCVFDACQYRGHPSSF----CNAIGLYVSACQAAGVQIQEWRSATFCPLSCPLNSHYELCGNGCPVTCSG--LASPTGCV-APCKESCSCDNGFILSGHKCVPIASCGCVYQNKYYQSNE---VFYPNGQCSE 1946 HSP 2 Score: 150.214 bits (378), Expect = 6.828e-35 Identity = 103/352 (29.26%), Postives = 169/352 (48.01%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELG--QKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C AVGDPH+RT+DG+ F G C YT+ + + D FNIE +NE RG N Y V + ++ L + G ++VN Q R+P +D VR+++S + + S++V +D +S V +S + + ++G+CG+ NG DD T +G N + G S+ V C +H+ C D + +++ CG+L + + PF +C G+VD + + +CV D+C+N +++ C+ A+ C + +WR CP+QC +N+ + + CP TC + T C + EGC C GY+ D C+ C CI
Sbjct: 16 CWAVGDPHFRTFDGRFYDFQGTCTYTIAKTSGSDSSLPVFNIEAKNENRG-NTRVAYVSFVTVQVYGFTMSLVRYENGFVRVNDQRQRLPMNLNDGQVRLYQSGSMV-VIETDFSMKVYYDWNSILKVSISSSFYESVSGMCGNYNGNPGDDLVTPAGTQAPNLVD----FGKSWKVEDGDRFC-------WHNCNGECKTCSLDLQKQYASEQTCGLLSKADGPFRQC--HGSVDPKVYVDNCVYDLCMNGGS----KQILCQSIKSYADACQRNKIQIAEWRQPSACPMQCPENSQYKLCSKGCPSTCNDD--ATPSTCSE-SCVEGCECKDGYVLDEGKCIPKSSCGCI 345 HSP 3 Score: 143.28 bits (360), Expect = 8.372e-33 Identity = 107/346 (30.92%), Postives = 163/346 (47.11%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ--KGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHF--FGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+A GDPHY ++DG F G C Y L + + F + VQNE RG +K YT +V + + + + K + VN L+ +PY + + F + +RV ++ DS V++ Y+ + G+CG+ +G +++ T V+ K L GNS+ V PG + + D S + + +R +K+ CG+L++ + PF C K VD + F+DCV D C R Q + C++ +G A C AG WRS CP+ CGKN+H+ A+ CP TC G C EGC C+ G+I G CV C C
Sbjct: 406 CTASGDPHYVSFDGVRYDFQGTCIYQLAGLCKKTEGLVDFTVNVQNENRG-SKVVAYTSAVNVTLCNLQIGITRQYKDRILVNQVLTNLPYSVENGKLSIYKQGFNAILQTSFGLRVVYNWDSYVEVKIPSTYAGAVCGLCGNYDGDKNNEFTMKNNQVATKP---LLFGNSWKVQNVPGCYEEDKGDCSNLA---ELELRHRASKESCGMLIDKSGPFRDCHAK--VDPQGAFKDCVYDSCFYAGR----QDILCKVIAGYAAACQRAGLNIEPWRSAKFCPV-CGKNSHYEVCASACPSTCLALAPPMGCSGEC-----SEGCECDDGFILSGGDCVPISQCGC 732 HSP 4 Score: 136.732 bits (343), Expect = 7.522e-31 Identity = 94/349 (26.93%), Postives = 147/349 (42.12%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDD-PCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHC-KKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRP------CYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+C A GDPHY ++DG F G C YTL + +D F++ V+NE G N T+ V++ ++ + + V+G++ ++P DD + + ++V +D + V V Y KM G+CG+ NG + D + V N++ G ++ VS G C D + +C ++ K CG++ P+ PF C K + +F C D C + + C+ VC G WR+ CPL C N+H+ C RTC+ G P C+ EGC CN G++ DG CV C C
Sbjct: 1985 RCVAQGDPHYISFDGLTFDFQGTCTYTLAKVVDDDSRLVKFSVGVENESYG-NGNVAVTRLVVVSVYGYSIAIERGMKWNVDGEILKLPLSLDDDSIVINQEGNNIVIQTDFGLKVLYDAVYHVVVNVPSSYRGKMGGLCGNFNGDKSDEFQLPNKQVVKNVNQF---GAAWKVSIAGAKCYDDCGDKCF--VCDPPKLQPFKGTASCGMITNPSGPFRACHSK--ISPTEYFDHCTYDSCAAEGK----DDFLCKSLQAYTAVCQTVGVAIENWRTASFCPLSCPANSHYEL----CTRTCDQTCTGISSPTKCTTRCF-----EGCECNAGFVSDGEKCVSMDKCGC 2312 HSP 5 Score: 130.183 bits (326), Expect = 6.987e-29 Identity = 110/397 (27.71%), Postives = 166/397 (41.81%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKY-FTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK--AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI------NLCVDRESSEKCRKWKQQGQ-CKELSEAMNIICPKTCGFCK 1372
F CSA GDPHY + DG F G C YTLT+ + F + V+NE GD K T S+ ++ + + + +G + VN L +P D VR ++ + V+V++D + V V Y ++ G+CG+ N R D+F+ R ++ + G+S+ V PG C + + + C + +CG L + + P S C G ++ +F +C+ D+C C VC AG WRS CPL C N+ + A+ C TC TK P EGC C+ G+ DG CV +C C N+ V + SE C G C++ + IC T G K
Sbjct: 790 FGTCSAAGDPHYMSLDGLAFDFQGTCTYTLTKSITSNANLVPFAVNVKNEKYGDGKVAVTKLVSLEVYGYTLILQYNTQGRILVNNVLYNLPLTLEDGKVRAYQ-HGIRTNIETDFGVKVSYDLVYHVIVTVPGNYKGQVGGLCGNFNDDRKDEFQLPDKRLTADA----TTFGSSWKVQIPGVSCDEGCGGNGNPCPACDAKKKEIFQTDNYCGFLKKKDGPLSAC--YGTINPDTYFNNCLFDVCAGAGD----GDTLCRSIQSYVAVCQAAGIAIQSWRSDSFCPLTCPANSKYKVCADVCSTTCAGVTDFTKCP---TTCSEGCECDDGFFFDGKNCVSMDNCGCFEDGRYYNVIVSNDCSEVCTCSPMGGLICEKTGCTSDEICKVTDGIVK 1172 HSP 6 Score: 111.694 bits (278), Expect = 3.080e-23 Identity = 100/392 (25.51%), Postives = 167/392 (42.60%), Query Frame = 2
Query: 95 VEKEPCTNGTRNIRITTYVKD-NGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDP-CSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS--ICGKDWIRSLKAKKHCGVLLEP-NNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
V K+PC + + T ++D N VC P T T C A GDPHY T+DG F G C Y L+++ D F IE +N+ RG ++ Y ++V I+M+ + G+ G +++N ++ +P D V ++V ++ + V +S Y G+CG+ N +D ++ +K + I + K D + C + ++ CG++ + N PF +C K N D NFF +C+ D+C+N ++ C+ + A C + G + WR+ C L C +N+H+ N CP +C + ++ C D E C CN G++ CV C C
Sbjct: 1174 VNKDPCKSMKCRTKETCKIQDGNAVCVPDYTGT-------------CWAWGDPHYHTFDGYNYDFQGTCTYILSKYIGNDPGLVPFTIEEKNDNRG-SQTVAYVRTVNIYMYGYKVSIVKGEFGKVRINDVVANLPVALLDGKISVSISGANAVVKTDFGLQVTYEYNWYVVVTLSSSYYGATGGLCGNFNQNSND------EMIAADGSKVTAIVDWAKTWKVNDRDPFCWDFCRGNCPTCDDSKKSTYGGEQFCGLISKAANGPFRECHPKINPD--NFFDNCLYDVCINGGA----KQFLCQALTAYANTCRKQGAKIYDWRTPSGCVLPCPENSHYEFCGNACPASCSDRTAPSR--CTDAC-VETCQCNDGFVLSADKCVPVKSCGC 1536
BLAST of VWFD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000000615.1 (Fc fragment of IgG binding protein [Source:NCBI gene;Acc:100379885]) HSP 1 Score: 160.999 bits (406), Expect = 4.004e-38 Identity = 123/399 (30.83%), Postives = 178/399 (44.61%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKRK-------DFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKE 1321
VCTP K C F CSA GDPHY T+DG+ F G C Y L D + F ++VQN RG NK +YTK V + ++ V L + V+G + +P Y+ +D V + S + + V +D S V V Y+ +NG+CG+ N DD K+G N G+S+ V + PG + S +C + + K++K+CG++ + N PFS+C+ +D FF DCV D C + PS + C C AG + +WRS CPL C N+H+ N CP TC + C P +E C+C+ G+I G CV C C+ +S+E + GQC E
Sbjct: 1984 VCTPTSCKASEKCLVVNGVRGCHPISFSTCSAYGDPHYTTFDGRRFDFMGTCVYQLVGVTSSDASLTRFTVKVQNNNRG-NKAVSYTKVVTVEVYNMVLTLSMDFPRRILVDGVATALPWYDGTDRVSAYISGN-QGIIKTDFDLTVVYDWSSYVAVTVPSTYTNAVNGLCGNNNKNPNDDLTMKNGNAAGNAVQ----FGDSWKVGEVPGC---TPECTSNCPLCSEAQKQDYKSEKYCGIITKANGPFSQCSSV--IDPTPFFNDCVFDACQYRGHPSSF----CNAIGLYVSACQAAGVQIQEWRSATFCPLSCPLNSHYELCGNGCPVTCSG--LASPTGCV-APCKESCSCDNGFILSGHKCVPIASCGCVYQNKYYQSNE---VFYPNGQCSE 2361 HSP 2 Score: 154.836 bits (390), Expect = 2.960e-36 Identity = 121/424 (28.54%), Postives = 188/424 (44.34%), Query Frame = 2
Query: 23 LLIITLSFYQFAKATRYGVCQNTKV-EKEPC--TNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELG--QKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
LI L FY F C+ TK KE C TNG VC P C AVGDPH+RT+DG+ F G C YT+ + + D FNIE +NE RG N Y V + ++ L + G ++VN Q R+P +D VR+++S + + S++V +D +S V +S + + ++G+CG+ NG DD T +G N + G S+ V C +H+ C D + +++ CG+L + + PF +C G+VD + + +CV D+C+N +++ C+ A+ C + +WR CP+QC +N+ + + CP TC + T C + EGC C GY+ D C+ C CI
Sbjct: 384 FLINNLPFYIFPSGVAVASCETTKCRSKEKCQMTNGKP------------VCIPTSESI-------------CWAVGDPHFRTFDGRFYDFQGTCTYTIAKTSGSDSSLPVFNIEAKNENRG-NTRVAYVSFVTVQVYGFTMSLVRYENGFVRVNDQRQRLPMNLNDGQVRLYQSGSMV-VIETDFSMKVYYDWNSILKVSISSSFYESVSGMCGNYNGNPGDDLVTPAGTQAPNLVD----FGKSWKVEDGDRFC-------WHNCNGECKTCSLDLQKQYASEQTCGLLSKADGPFRQC--HGSVDPKVYVDNCVYDLCMNGGS----KQILCQSIKSYADACQRNKIQIAEWRQPSACPMQCPENSQYKLCSKGCPSTCNDD--ATPSTCSE-SCVEGCECKDGYVLDEGKCIPKSSCGCI 760 HSP 3 Score: 142.895 bits (359), Expect = 9.856e-33 Identity = 107/349 (30.66%), Postives = 164/349 (46.99%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ--KGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHF--FGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ C+A GDPHY ++DG F G C Y L + + F + VQNE RG +K YT +V + + + + K + VN L+ +PY + + F + +RV ++ DS V++ Y+ + G+CG+ +G +++ T V+ K L GNS+ V PG + + D S + + +R +K+ CG+L++ + PF C K VD + F+DCV D C R Q + C++ +G A C AG WRS CP+ CGKN+H+ A+ CP TC G C EGC C+ G+I G CV C C
Sbjct: 818 YGTCTASGDPHYVSFDGVRYDFQGTCIYQLAGLCKKTEGLVDFTVNVQNENRG-SKVVAYTSAVNVTLCNLQIGITRQYKDRILVNQVLTNLPYSVENGKLSIYKQGFNAILQTSFGLRVVYNWDSYVEVKIPSTYAGAVCGLCGNYDGDKNNEFTMKNNQVATKP---LLFGNSWKVQNVPGCYEEDKGDCSNLA---ELELRHRASKESCGMLIDKSGPFRDCHAK--VDPQGAFKDCVYDSCFYAGR----QDILCKVIAGYAAACQRAGLNIEPWRSAKFCPV-CGKNSHYEVCASACPSTCLALAPPMGCSGEC-----SEGCECDDGFILSGGDCVPISQCGC 1147 HSP 4 Score: 130.183 bits (326), Expect = 8.110e-29 Identity = 110/397 (27.71%), Postives = 166/397 (41.81%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKY-FTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK--AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI------NLCVDRESSEKCRKWKQQGQ-CKELSEAMNIICPKTCGFCK 1372
F CSA GDPHY + DG F G C YTLT+ + F + V+NE GD K T S+ ++ + + + +G + VN L +P D VR ++ + V+V++D + V V Y ++ G+CG+ N R D+F+ R ++ + G+S+ V PG C + + + C + +CG L + + P S C G ++ +F +C+ D+C C VC AG WRS CPL C N+ + A+ C TC TK P EGC C+ G+ DG CV +C C N+ V + SE C G C++ + IC T G K
Sbjct: 1205 FGTCSAAGDPHYMSLDGLAFDFQGTCTYTLTKSITSNANLVPFAVNVKNEKYGDGKVAVTKLVSLEVYGYTLILQYNTQGRILVNNVLYNLPLTLEDGKVRAYQ-HGIRTNIETDFGVKVSYDLVYHVIVTVPGNYKGQVGGLCGNFNDDRKDEFQLPDKRLTADA----TTFGSSWKVQIPGVSCDEGCGGNGNPCPACDAKKKEIFQTDNYCGFLKKKDGPLSAC--YGTINPDTYFNNCLFDVCAGAGD----GDTLCRSIQSYVAVCQAAGIAIQSWRSDSFCPLTCPANSKYKVCADVCSTTCAGVTDFTKCP---TTCSEGCECDDGFFFDGKNCVSMDNCGCFEDGRYYNVIVSNDCSEVCTCSPMGGLICEKTGCTSDEICKVTDGIVK 1587 HSP 5 Score: 125.946 bits (315), Expect = 1.357e-27 Identity = 93/350 (26.57%), Postives = 141/350 (40.29%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDD-PCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLK-VNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHC-KKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRP------CYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+C A GDPHY ++DG F G C YTL + +D F++ V+NE G+ G V + V+G++ ++P DD + + ++V +D + V V Y KM G+CG+ NG + D + V N++ G ++ VS G C D + +C ++ K CG++ P+ PF C K + +F C D C + + C+ VC G WR+ CPL C N+H+ C RTC+ G P C+ EGC CN G++ DG CV C C
Sbjct: 2400 RCVAQGDPHYISFDGLTFDFQGTCTYTLAKVVDDDSRLVKFSVGVENESYGN---------------------GNVAVTRLVDGEILKLPLSLDDDSIVINQEGNNIVIQTDFGLKVLYDAVYHVVVNVPSSYRGKMGGLCGNFNGDKSDEFQLPNKQVVKNVNQF---GAAWKVSIAGAKCYDDCGDKCF--VCDPPKLQPFKGTASCGMITNPSGPFRACHSK--ISPTEYFDHCTYDSCAAEGK----DDFLCKSLQAYTAVCQTVGVAIENWRTASFCPLSCPANSHYEL----CTRTCDQTCTGISSPTKCTTRCF-----EGCECNAGFVSDGEKCVSMDKCGC 2708 HSP 6 Score: 111.309 bits (277), Expect = 4.196e-23 Identity = 100/392 (25.51%), Postives = 167/392 (42.60%), Query Frame = 2
Query: 95 VEKEPCTNGTRNIRITTYVKD-NGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDP-CSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS--ICGKDWIRSLKAKKHCGVLLEP-NNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
V K+PC + + T ++D N VC P T T C A GDPHY T+DG F G C Y L+++ D F IE +N+ RG ++ Y ++V I+M+ + G+ G +++N ++ +P D V ++V ++ + V +S Y G+CG+ N +D ++ +K + I + K D + C + ++ CG++ + N PF +C K N D NFF +C+ D+C+N ++ C+ + A C + G + WR+ C L C +N+H+ N CP +C + ++ C D E C CN G++ CV C C
Sbjct: 1589 VNKDPCKSMKCRTKETCKIQDGNAVCVPDYTGT-------------CWAWGDPHYHTFDGYNYDFQGTCTYILSKYIGNDPGLVPFTIEEKNDNRG-SQTVAYVRTVNIYMYGYKVSIVKGEFGKVRINDVVANLPVALLDGKISVSISGANAVVKTDFGLQVTYEYNWYVVVTLSSSYYGATGGLCGNFNQNSND------EMIAADGSKVTAIVDWAKTWKVNDRDPFCWDFCRGNCPTCDDSKKSTYGGEQFCGLISKAANGPFRECHPKINPD--NFFDNCLYDVCINGGA----KQFLCQALTAYANTCRKQGAKIYDWRTPSGCVLPCPENSHYEFCGNACPASCSDRTAPSR--CTDAC-VETCQCNDGFVLSADKCVPVKSCGC 1951
BLAST of VWFD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000000905.1 (IgGFc-binding protein-like [Source:NCBI gene;Acc:100492852]) HSP 1 Score: 150.599 bits (379), Expect = 4.983e-35 Identity = 107/347 (30.84%), Postives = 170/347 (48.99%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDN--KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+CSA GDPHY TYDG +F G C+Y L+ +++ + F + V+N+ RG Y T I M ++ VL V+G LS +P S + +F+S + + + +RVAFD D+ V + Y+ + G+CG+ N DD T G ++ GNS+ V+ PG ++ + ++ + ++ K+K CG++L+ PF +C + ++FQDC+ DMC RP + C + +G C EAG WRS+ C L C N+H++ + CP TC + + C D+ +EGCAC+ GY+ G CV C C
Sbjct: 435 QCSASGDPHYITYDGLHYNFQGTCQYKLSGLCKQNKGLTDFQVNVRNQNRGSRAVSYVTAVNLTIYSMEIQIRRDYPDQVL-VDGLLSNLPLTLSSGRISVFRSGRHC-IIQSQLGLRVAFDWDARVAVTIPSSYAGSVCGLCGNFNNQPDDDLMTLDGSITTDSIE----FGNSWKVADLPGCSGGAPENCNLTAL---EKVQR-KSKTECGMILDKKGPFRECHSI--IPPEDYFQDCIFDMCAYGKRP----DISCRLINGYTSACQEAGANIYPWRSEEFCKLPCDDNSHYNVCTSACPSTCLS--LASHTTC-DIKCQEGCACDDGYVLSGGHCVPLSDCGC 762 HSP 2 Score: 127.872 bits (320), Expect = 3.692e-28 Identity = 108/386 (27.98%), Postives = 173/386 (44.82%), Query Frame = 2
Query: 215 KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLK--VNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGH----HCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT--KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRES-SEKCRKWKQQGQCKELSEAM 1336
+D+ C + GDPHY T+DG+ +F G C Y L D + F + VQNE RG K +YTK+V + ++ + L + L+ VNG L +P+ +S+ ++ F R FV V V F+ D+ A V + RY + G+CG+ N +DD G V + +G+ + + C + + Y K +K+CG+L + + PF +C G +D + DCV D C K + C+ F+ A C E G WR+ CP C N+H+ + C TC ++ C EGC C+ G+++ G CV C C+ RE+ +K ++ G CK+ + +
Sbjct: 1619 EDYTTCVSSGDPHYTTFDGRKYNFMGTCIYQLAGVCSTDPTLTPFQVNVQNEARG-KKTVSYTKAVTLQVYGQNITLTRNYPLQILVNGVLKSLPFSFRSNKIKAFM-RGEHCFVRTDFDVTVNFNWDNYARVVLPSRYIGAVCGLCGNNNKDPKDDVPVADGDQVPDSFGDAWKVGDVAGCTSGCNGKCPECSETDTLKY------------KDEKYCGILSKDDGPFKEC--YGVIDPTPYLTDCVYDSCQYKG----YYSAVCDAFALYASRCQEKGVNIEPWRTPTFCP-TCPPNSHYEMCGSGCQPTCSGLITSDDCQKSC-----TEGCYCDSGFLQSGGQCVPFAECGCLY----REAYYKKGEEFYPDGDCKQFCQCL 1974 HSP 3 Score: 110.923 bits (276), Expect = 5.151e-23 Identity = 95/356 (26.69%), Postives = 146/356 (41.01%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDD----PCSFNIEVQNEYRGD---NKYFT---YTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQF--VAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS----ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CS VGD Y T+D Q FYG+C Y L++ D P +++ Q G K T Y +V I++ E+ L VNG L +P+ D+ K R Q V R + D + V V Y G+CGD N + D D+S + + +S+ S C ++ + IC + + LK +CG+L++ + PF+ C G +D + + CV +C C I +C +G + WR+ CPL C +N+HF + C +C + + + P EGC C+ GY+ G CV P C C
Sbjct: 823 CSVVGDGSYWTFDNQKYEFYGNCSYILSKSCLPDGSKLTPYVIHLQNQEVVTGGVTKRKVLTLEAYGYNVTIYIESEITML-------VNGILQNLPF----DLESGKLRGDHQGLGVVLRADFGLVITSDFSLHVTVPGNYHNYTCGLCGDYNEIPQD-------DISPADDVVTF-ADSWKDSNSDMFCGSSELCGGENQTCPICPSNKAKILKGNNYCGILVKSDGPFAAC--HGTIDPKMYRASCVNSLCDGTGD-------LCLILQNYVAICQASGVQMNSWRTPSFCPLTCPENSHFESCVDLCTTSCSSLYDTSICP---TSCSEGCECDEGYLFQGGQCVPPKQCGC 1147 HSP 4 Score: 109.383 bits (272), Expect = 1.495e-22 Identity = 88/355 (24.79%), Postives = 140/355 (39.44%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDP-CSFNIEVQNEYRGDNKY-FTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRC------SVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEP-NNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER------EGCACNRGYIRDGALCVKPMHCKC 1249
C A G PHY+TYD F G C Y LT++ +D F IE Q E RG F V ++ ++ G+ G ++VN ++ P V + + + F ++V +D ++ V + Y G+CG+ N DD K S +++ S+ V+ C A + + C + I CG+L + N PF +C ++ FF +C+ D+C + + C AE+C G WR+ CP C +N+H+ CP +C + + P R E C C+ G+I CV C C
Sbjct: 1233 CWAWGAPHYQTYDNFNYQFEGTCTYVLTEYIGQDTTLVPFRIEEQKENRGSPIISFIRQIDVFVYGYKISVAKGEYGKVRVNDEIGNTP------VTLLNGKISVTFSGSEAILNTDFGLQVTYDYNTKVMVSIPSSYYASTGGLCGNFNQDPDDEKVSSDNKPVESVTEWA---KSWKVNVNDSFCWDACE-GNCTACDDNMISQYSQDNACGLLNKTINGPFRECLSI--INPERFFSNCLYDLC----NSGQALNIHCTTLQSYAEMCRSQGVTIYDWRTSSECPFPCPENSHYEVCGTSCPASCFDR---------NAPNRCTEACVETCQCDDGFILSAGKCVPIESCGC 1562 HSP 5 Score: 105.145 bits (261), Expect = 3.037e-21 Identity = 87/358 (24.30%), Postives = 158/358 (44.13%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL----GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKS--GRDVSNKRNKYSLIGNSYHV-----SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVL-LEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTK--RPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHY T+D + F G C YT+++ + D FNIE NE RG + +Y + ++ ++ Y + + G+++VN Q ++P K ++ + +S L V +RV +D + + + +S+ + G+CG+ N + DD ++ D + + G+S + P C + Y CG++ L+ N PF C VD R + +C+ D+C+N +Q++ C+ ++ C + +WR+ C ++C N+ + + C TCE+ +K PC E C CN G++ C+ +C C+
Sbjct: 45 CWAWGDPHYHTFDSRNYDFQGTCTYTMSKTCGTDPDLPPFNIETTNENRG-SSLVSYISNALVQVYG--YNITSYRAEIGIVRVNNQRVQLPVTLKGGNLTLQQSGSLLVLVTDF-GLRVFYDWNMLFKIYLPSSFSENVCGLCGNFNNIPGDDLYSQDHVSLDPIAYGQLWKVQGSSSSTCWDDCNGPCKTCSPSDKQKYAD------------PSSCGIIALKENGPFRLC--HAAVDPRIYLDNCIYDLCLNDG----FQQILCQTLKTYSDACRRENVQVFEWRNATGCNMECLPNSAYKFCGSACSPTCEDPDAPSKCTEPCI-----ETCECNAGFVMIEGKCMPKENCGCL 375 HSP 6 Score: 100.138 bits (248), Expect = 9.228e-20 Identity = 92/349 (26.36%), Postives = 146/349 (41.83%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNRED-DPCSFNIEVQNEYRGDNKYF--TYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRS--LKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCEN-HFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C HY ++DG +F G C YTLT+ R D +F+I V+N G++K +SV I+++ L + + + R+ E S ++ + + SV+V GD Y + + G+CGD NG DDF+ SG+ + + + S G+ CK D G D +R+ + CG +L PF++C K V++ +F C+ DMC + + + C C AG WR+ C C +N+H+ A C +C G+ C+ EGC C+ GY+ DG CV C C+
Sbjct: 2009 CGVSASTHYSSFDGLSYNFQGSCSYTLTEVCRGDLRLANFSIVVEN---GNDKQSNQAVLRSVSINVYGHEIVLTKDTLWTIQVSQIRITPEGS-NILLQTDFALTVLYSTLGSVQVTVPGD----------YQEALCGLCGDFNGQSNDDFRLPSGQLADSLEDFGEAWVTNQERSDCGNVCKANCD-------GCDPLRAAIFARDEACGQILLETGPFAEC--KALVNVTEYFDHCLFDMCASDGQ----NQALCASLQAFVAACQAAGANVQPWRTSTLCSPSCPRNSHYDVCAQTCDGSCAAIDLSGSCSERCF-----EGCECDDGYMFDGKNCVPMEKCGCV 2325
BLAST of VWFD domain-containing protein vs. Ensembl Xenopus
Match: ENSXETT00000000951.1 (IgGFc-binding protein-like [Source:NCBI gene;Acc:100492852]) HSP 1 Score: 150.214 bits (378), Expect = 6.447e-35 Identity = 107/347 (30.84%), Postives = 170/347 (48.99%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDN--KYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+CSA GDPHY TYDG +F G C+Y L+ +++ + F + V+N+ RG Y T I M ++ VL V+G LS +P S + +F+S + + + +RVAFD D+ V + Y+ + G+CG+ N DD T G ++ GNS+ V+ PG ++ + ++ + ++ K+K CG++L+ PF +C + ++FQDC+ DMC RP + C + +G C EAG WRS+ C L C N+H++ + CP TC + + C D+ +EGCAC+ GY+ G CV C C
Sbjct: 365 QCSASGDPHYITYDGLHYNFQGTCQYKLSGLCKQNKGLTDFQVNVRNQNRGSRAVSYVTAVNLTIYSMEIQIRRDYPDQVL-VDGLLSNLPLTLSSGRISVFRSGRHC-IIQSQLGLRVAFDWDARVAVTIPSSYAGSVCGLCGNFNNQPDDDLMTLDGSITTDSIE----FGNSWKVADLPGCSGGAPENCNLTAL---EKVQR-KSKTECGMILDKKGPFRECHSI--IPPEDYFQDCIFDMCAYGKRP----DISCRLINGYTSACQEAGANIYPWRSEEFCKLPCDDNSHYNVCTSACPSTCLS--LASHTTC-DIKCQEGCACDDGYVLSGGHCVPLSDCGC 692 HSP 2 Score: 127.872 bits (320), Expect = 4.013e-28 Identity = 108/386 (27.98%), Postives = 173/386 (44.82%), Query Frame = 2
Query: 215 KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS-FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLK--VNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGH----HCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT--KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRES-SEKCRKWKQQGQCKELSEAM 1336
+D+ C + GDPHY T+DG+ +F G C Y L D + F + VQNE RG K +YTK+V + ++ + L + L+ VNG L +P+ +S+ ++ F R FV V V F+ D+ A V + RY + G+CG+ N +DD G V + +G+ + + C + + Y K +K+CG+L + + PF +C G +D + DCV D C K + C+ F+ A C E G WR+ CP C N+H+ + C TC ++ C EGC C+ G+++ G CV C C+ RE+ +K ++ G CK+ + +
Sbjct: 1548 EDYTTCVSSGDPHYTTFDGRKYNFMGTCIYQLAGVCSTDPTLTPFQVNVQNEARG-KKTVSYTKAVTLQVYGQNITLTRNYPLQILVNGVLKSLPFSFRSNKIKAFM-RGEHCFVRTDFDVTVNFNWDNYARVVLPSRYIGAVCGLCGNNNKDPKDDVPVADGDQVPDSFGDAWKVGDVAGCTSGCNGKCPECSETDTLKY------------KDEKYCGILSKDDGPFKEC--YGVIDPTPYLTDCVYDSCQYKG----YYSAVCDAFALYASRCQEKGVNIEPWRTPTFCP-TCPPNSHYEMCGSGCQPTCSGLITSDDCQKSC-----TEGCYCDSGFLQSGGQCVPFAECGCLY----REAYYKKGEEFYPDGDCKQFCQCL 1903 HSP 3 Score: 110.538 bits (275), Expect = 6.203e-23 Identity = 95/356 (26.69%), Postives = 146/356 (41.01%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDD----PCSFNIEVQNEYRGD---NKYFT---YTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQF--VAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS----ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CS VGD Y T+D Q FYG+C Y L++ D P +++ Q G K T Y +V I++ E+ L VNG L +P+ D+ K R Q V R + D + V V Y G+CGD N + D D+S + + +S+ S C ++ + IC + + LK +CG+L++ + PF+ C G +D + + CV +C C I +C +G + WR+ CPL C +N+HF + C +C + + + P EGC C+ GY+ G CV P C C
Sbjct: 753 CSVVGDGSYWTFDNQKYEFYGNCSYILSKSCLPDGSKLTPYVIHLQNQEVVTGGVTKRKVLTLEAYGYNVTIYIESEITML-------VNGILQNLPF----DLESGKLRGDHQGLGVVLRADFGLVITSDFSLHVTVPGNYHNYTCGLCGDYNEIPQD-------DISPADDVVTF-ADSWKDSNSDMFCGSSELCGGENQTCPICPSNKAKILKGNNYCGILVKSDGPFAAC--HGTIDPKMYRASCVNSLCDGTGD-------LCLILQNYVAICQASGVQMNSWRTPSFCPLTCPENSHFESCVDLCTTSCSSLYDTSICP---TSCSEGCECDEGYLFQGGQCVPPKQCGC 1077 HSP 4 Score: 98.9821 bits (245), Expect = 2.069e-19 Identity = 88/358 (24.58%), Postives = 140/358 (39.11%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDP-CSFNIEVQNEYRGDNKY-FTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRC------SVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEP-NNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRS---QFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER------EGCACNRGYIRDGALCVKPMHCKC 1249
C A G PHY+TYD F G C Y LT++ +D F IE Q E RG F V ++ ++ G+ G ++VN ++ P V + + + F ++V +D ++ V + Y G+CG+ N DD K S +++ S+ V+ C A + + C + I CG+L + N PF +C ++ FF +C+ D+C + + C AE+C G WR+ F CP +N+H+ CP +C + + P R E C C+ G+I CV C C
Sbjct: 1163 CWAWGAPHYQTYDNFNYQFEGTCTYVLTEYIGQDTTLVPFRIEEQKENRGSPIISFIRQIDVFVYGYKISVAKGEYGKVRVNDEIGNTP------VTLLNGKISVTFSGSEAILNTDFGLQVTYDYNTKVMVSIPSSYYASTGGLCGNFNQDPDDEKVSSDNKPVESVTEWA---KSWKVNVNDSFCWDACE-GNCTACDDNMISQYSQDNACGLLNKTINGPFRECLSI--INPERFFSNCLYDLC----NSGQALNIHCTTLQSYAEMCRSQGVTIYDWRTSSESFPCP----ENSHYEVCGTSCPASCFDR---------NAPNRCTEACVETCQCDDGFILSAGKCVPIESCGC 1491 HSP 5 Score: 97.4413 bits (241), Expect = 5.250e-19 Identity = 91/348 (26.15%), Postives = 148/348 (42.53%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNRED-DPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRS--LKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCEN-HFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C HY ++DG +F G C YTLT+ R D +F+I V+N G++K ++V+ F +VNG+ + +P ++ +RI + + ++ V + + V V Y + + G+CGD NG DDF+ SG+ + + + S G+ CK D G D +R+ + CG +L PF++C K V++ +F C+ DMC + + + C C AG WR+ C C +N+H+ A C +C G+ C+ EGC C+ GY+ DG CV C C+
Sbjct: 1938 CGVSASTHYSSFDGLSYNFQGSCSYTLTEVCRGDLRLANFSIVVEN---GNDK--QSNQAVLRLCFPP----------QVNGETNALPLTLENKKIRITPEGSNI-LLQTDFALTVLYSTLGSVQVTVPGDYQEALCGLCGDFNGQSNDDFRLPSGQLADSLEDFGEAWVTNQERSDCGNVCKANCD-------GCDPLRAAIFARDEACGQILLETGPFAEC--KALVNVTEYFDHCLFDMCASDGQ----NQALCASLQAFVAACQAAGANVQPWRTSTLCSPSCPRNSHYDVCAQTCDGSCAAIDLSGSCSERCF-----EGCECDDGYMFDGKNCVPMEKCGCV 2251 HSP 6 Score: 78.9518 bits (193), Expect = 2.405e-13 Identity = 73/325 (22.46%), Postives = 139/325 (42.77%), Query Frame = 2
Query: 326 EDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL----GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKS--GRDVSNKRNKYSLIGNSYHV-----SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVL-LEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTK--RPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+ D FNIE NE RG + +Y + ++ ++ Y + + G+++VN Q ++P K ++ + +S L V +RV +D + + + +S+ + G+CG+ N + DD ++ D + + G+S + P C + Y CG++ L+ N PF C VD R + +C+ D+C+N +Q++ C+ ++ C + +WR+ C ++C N+ + + C TCE+ +K PC E C CN G++ C+ +C C+
Sbjct: 8 DPDLPPFNIETTNENRG-SSLVSYISNALVQVYG--YNITSYRAEIGIVRVNNQRVQLPVTLKGGNLTLQQSGSLLVLVTDF-GLRVFYDWNMLFKIYLPSSFSENVCGLCGNFNNIPGDDLYSQDHVSLDPIAYGQLWKVQGSSSSTCWDDCNGPCKTCSPSDKQKYAD------------PSSCGIIALKENGPFRLC--HAAVDPRIYLDNCIYDLCLNDG----FQQILCQTLKTYSDACRRENVQVFEWRNATGCNMECLPNSAYKFCGSACSPTCEDPDAPSKCTEPCI-----ETCECNAGFVMIEGKCMPKENCGCL 305
BLAST of VWFD domain-containing protein vs. Ensembl Mouse
Match: 9530053A07Rik (RIKEN cDNA 9530053A07 gene [Source:MGI Symbol;Acc:MGI:2442118]) HSP 1 Score: 150.984 bits (380), Expect = 3.093e-35 Identity = 104/350 (29.71%), Postives = 166/350 (47.43%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDV-RIFKS--RKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRP--CYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHY T+DG G C YT+ + + +D +F ++ +NE+R NK +Y + V +H + L G+ G+ K++ Q S +P S+ + R+ +S R L+ + V +D D + + KR+ +++G+CG+ NG DDF T G+ + N S+ V+ C + S C + K CG+L P+ PF+ C + +D + F ++CV DMCV + C + A+ C + G +WRS+ NCPL C N+H+ + CP +C + RP C P EGC C G++ LC+ C CI
Sbjct: 56 CRAQGDPHYTTFDGHRYDMMGTCTYTMAELRSSKDSLLAFKVDAKNEHRSSNK-VSYVRLVTVHAYNHTVSLIYGEVGLAKIDYQYSSLPVSLSEGLLRVHQSGTRGVLEL---DFGLVVTYDWDGQLTLSLPKRFQDQVSGLCGNYNGDPADDFLTPDGKQAPDVLN----FTKSWKVNDQDLLCDDGCYGNCPS-CIPSQAQLFKKDLFCGMLTLPSGPFADCHQF--LDPKPFLEECVYDMCVTGGE----RLTLCRGLNAYAQACVDLGISVREWRSRTNCPLTCPANSHYELCSPACPPSCNSE----ARPTNCSSRPCVEGCVCLPGFVASRGLCMPVSSCGCI 386 HSP 2 Score: 114.39 bits (285), Expect = 3.102e-24 Identity = 91/348 (26.15%), Postives = 148/348 (42.53%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ-KGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSL----KAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C G HY T+DG+ F G C + L Q F I +N +G NK + TK + I + +L Q + +KVNG ++P +D V+ F+ + + + + V++D + V+V Y K M G+CGD N ++DF+ G ++ +G+S+ + PG C C +L + K+ CG++ P P + C + +D + Q CV D+C+ Q + C C AG WR+Q CP++C ++H+ A+ C C T C P EGC C+ +++ CV C C
Sbjct: 834 CQVSGASHYTTFDGRHFDFMGTCVHVLAQTCWTRPGLKPFTILQENAVQG-NKQVSVTKKITIEVANYTLQLEQNQWKVKVNGVDMKLPVLLDEDRVQAFRHGTDM-VIETKFGLLVSYDLKYSVRVKVPHNYYKHMCGLCGDYNDDPKNDFQKSDGSQAASSNE----LGDSWEKAVPGSSCTPRPSCKPGQACSPKCYPTLEKKYRGKEFCGLITSPTGPLAACHKL--LDPQGPLQSCVFDLCLGGGN----QSILCSSIHAYVSACQAAGGTVKPWRNQTFCPMECPPHSHYEVCADTCSLDCSA--ITTPMQCL-TPCSEGCECDTDFLQSITTCVPMEKCGC 1166 HSP 3 Score: 110.538 bits (275), Expect = 5.068e-23 Identity = 84/350 (24.00%), Postives = 144/350 (41.14%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
+C +GDP Y T DG F G C Y L+ H FN+ V NE+R ++ +YT+S+ + ++ L L V+G++ ++P++ + + S L V + + FDG+S + V Y+ + G+CG+ N DD G+ K + C + + + C + + CG++ P P + C V +F+ C++D C + C + C +A +WR CPLQC ++H+ + CP +C + G + C REGC C+ G++ G CV C C++
Sbjct: 1650 ECQILGDPTYITLDGHRFDFQGTCEYLLSAPCHAPPTGTEYFNVTVVNEHRC-SQAVSYTRSITLRIYGLSLTLSAHWPKNLLVDGEMVKLPFQLQSRLLVHLSGMGL-VVHTSWGLSLTFDGNSFMRLRVPAAYAGTLCGLCGNYNKNPNDDLTAVGGKPEGWKVGGFP-------------DCDQCQLRTCPKPCTPEERKRFGGPNACGIITAPEGPLAPC--HSFVPPTQYFEACLLDTCQVQGHSGG----LCPAIATYVAACQDARVRLREWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETIC-----REGCVCDAGFVLSGDTCVPVGQCGCLH 1973 HSP 4 Score: 97.8265 bits (242), Expect = 3.746e-19 Identity = 88/353 (24.93%), Postives = 156/353 (44.19%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLT----QHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ--KGVLKVNGQLSRVPYEK-SDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAK--KHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHY + D ++ +F G C Y T QH D F + ++NE RG ++ ++ +SV + E+ + +G + V+G L +P++ + +F+ K+ + S+ V+++ D++ +V Y + G+CG+ NG RDD + + + R+ G + VS H D + +C D+ + L + ++C + + F C R + + + +C D C R K C+ + +C +G WR++ CP+ C ++H+ CP TC + G CY E C C+ GY+ G CV C C+
Sbjct: 448 CRASGDPHYMSLDERIFNFMGTCTYLFTASCGQHPSLPD---FKVFIENERRG-SQSVSFVRSVKLEALGIKLEVRREYQGKVLVDGILHYLPFQALGGKLVVFRQGKY-AILRTNFSLSVSYNWDTHVTAKVPSNYFNSVCGLCGNFNGDPRDDLGKQIRAEAIDPRD----FGKKWLVSS---HLGCRTDEQH--LC-PDFNKGLVSNITQNCRIFTNISGHFKHCWRVPAYN--SAYIECAYDCC----RMPGQTKPLCDTLATYTAICQSSGVIVYPWRTETLCPMTCPPHSHYELCQRGCPLTCGDQPVPGGCGSDCY-----ESCVCDEGYVLSGEACVPLASCGCV 774 HSP 5 Score: 87.0409 bits (214), Expect = 6.816e-16 Identity = 76/342 (22.22%), Postives = 138/342 (40.35%), Query Frame = 2
Query: 251 HYRTYDGQVIHFYGDCRYTLTQ-----HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
HY T DG V YG C Y L Q H E +F+I ++ + G+ + T + +V L + + V+ ++ +P ++R F+ + +++ FDGD + + + + ++ G+CG+ NG + DDF SG N G ++ C + +C + + CG + +P PF+ C + ++ +F CV D+C + + C + C AG WR+ CP +C ++H+S + C +C + F G C+ EGC C+ ++ +C+ C C
Sbjct: 2039 HYATPDGLVYDLYGSCSYILAQVCFPKHGEE----AFSIVLEKDLAGNPQRVVVTVA------GQVVVLAKGPQVTVDSEVVALPMVVGSIYITAENRNV--FLQTKSGLKLLFDGDDHILISIPSPFRGRLCGLCGNFNGNQSDDFVLPSGVVAPNVE----AFGAAWRAPGSSLGCGEGCGPQGCPVCSAEKRELYEENDACGKIRDPQGPFAACHKA--LNHSEYFHQCVFDLCTHHGD----RDYLCRSLAAYTAACQAAGAAVKPWRTDSICPAECPAHSHYSICTHSCQGSCAAISGFTGCTTQCF-----EGCECDDHFLLSQGVCIPAQDCGCF 2353 HSP 6 Score: 79.7221 bits (195), Expect = 1.080e-13 Identity = 98/394 (24.87%), Postives = 165/394 (41.88%), Query Frame = 2
Query: 89 TKVEKEPCTNGTRNIRITTYVKDN-GVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLT----QHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVP-YEKSDDVRIFK--SRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLI--GNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVL-LEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVK 1231
T V K+PC T + T KD GVC + N ESK C GDPHY ++DG +F+G C Y + + F++ ++E + D K +Y + V + + + +K G ++VNG +P Y + + S+ L+ ++V ++ V + Y + G+CG+ D ++ + N S+ G S+ V C S + C +D + + CG L + PF+ C +V +FF+ CV+D+C+ + + + C+ + A C AG + WR+Q C + C N+H+ PCP +C T D P EGC C++G++ CV
Sbjct: 1217 TCVTKDPCQGVTCRSQETCTEKDGKGVC-------RANYESK------CWVWGDPHYHSFDGLNTNFHGTCSYLMAGTGCPGTGAEGLTPFSVITKHESQSDPK-VSYVRKVTVKTYNTSITIHEKKTGRVQVNGVFMALPVYLAGGRISVINGGSKAVLET---NFGLQVTYNWKWRVHVTLPSSYYGAVCGLCGNM-----DKNPQNDQVFPNGTMAPSIPTWGGSWQVPGWDPLCWNECQGSCPT-CPEDRVEEYRGPGFCGPLDHDTVGPFTSC--HAHVPPESFFEGCVLDVCLG----GQVKDILCQALADYAAACQAAGIKIEDWRTQAGCEITCPVNSHYELCGPPCPASCPPPARHTAPTACDGPCVEGCQCDKGFVLSADQCVP 1581
BLAST of VWFD domain-containing protein vs. Ensembl Mouse
Match: 9530053A07Rik (RIKEN cDNA 9530053A07 gene [Source:MGI Symbol;Acc:MGI:2442118]) HSP 1 Score: 150.984 bits (380), Expect = 3.093e-35 Identity = 104/350 (29.71%), Postives = 166/350 (47.43%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDV-RIFKS--RKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRP--CYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHY T+DG G C YT+ + + +D +F ++ +NE+R NK +Y + V +H + L G+ G+ K++ Q S +P S+ + R+ +S R L+ + V +D D + + KR+ +++G+CG+ NG DDF T G+ + N S+ V+ C + S C + K CG+L P+ PF+ C + +D + F ++CV DMCV + C + A+ C + G +WRS+ NCPL C N+H+ + CP +C + RP C P EGC C G++ LC+ C CI
Sbjct: 56 CRAQGDPHYTTFDGHRYDMMGTCTYTMAELRSSKDSLLAFKVDAKNEHRSSNK-VSYVRLVTVHAYNHTVSLIYGEVGLAKIDYQYSSLPVSLSEGLLRVHQSGTRGVLEL---DFGLVVTYDWDGQLTLSLPKRFQDQVSGLCGNYNGDPADDFLTPDGKQAPDVLN----FTKSWKVNDQDLLCDDGCYGNCPS-CIPSQAQLFKKDLFCGMLTLPSGPFADCHQF--LDPKPFLEECVYDMCVTGGE----RLTLCRGLNAYAQACVDLGISVREWRSRTNCPLTCPANSHYELCSPACPPSCNSE----ARPTNCSSRPCVEGCVCLPGFVASRGLCMPVSSCGCI 386 HSP 2 Score: 114.39 bits (285), Expect = 3.102e-24 Identity = 91/348 (26.15%), Postives = 148/348 (42.53%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ-KGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSL----KAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C G HY T+DG+ F G C + L Q F I +N +G NK + TK + I + +L Q + +KVNG ++P +D V+ F+ + + + + V++D + V+V Y K M G+CGD N ++DF+ G ++ +G+S+ + PG C C +L + K+ CG++ P P + C + +D + Q CV D+C+ Q + C C AG WR+Q CP++C ++H+ A+ C C T C P EGC C+ +++ CV C C
Sbjct: 834 CQVSGASHYTTFDGRHFDFMGTCVHVLAQTCWTRPGLKPFTILQENAVQG-NKQVSVTKKITIEVANYTLQLEQNQWKVKVNGVDMKLPVLLDEDRVQAFRHGTDM-VIETKFGLLVSYDLKYSVRVKVPHNYYKHMCGLCGDYNDDPKNDFQKSDGSQAASSNE----LGDSWEKAVPGSSCTPRPSCKPGQACSPKCYPTLEKKYRGKEFCGLITSPTGPLAACHKL--LDPQGPLQSCVFDLCLGGGN----QSILCSSIHAYVSACQAAGGTVKPWRNQTFCPMECPPHSHYEVCADTCSLDCSA--ITTPMQCL-TPCSEGCECDTDFLQSITTCVPMEKCGC 1166 HSP 3 Score: 110.538 bits (275), Expect = 5.068e-23 Identity = 84/350 (24.00%), Postives = 144/350 (41.14%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
+C +GDP Y T DG F G C Y L+ H FN+ V NE+R ++ +YT+S+ + ++ L L V+G++ ++P++ + + S L V + + FDG+S + V Y+ + G+CG+ N DD G+ K + C + + + C + + CG++ P P + C V +F+ C++D C + C + C +A +WR CPLQC ++H+ + CP +C + G + C REGC C+ G++ G CV C C++
Sbjct: 1650 ECQILGDPTYITLDGHRFDFQGTCEYLLSAPCHAPPTGTEYFNVTVVNEHRC-SQAVSYTRSITLRIYGLSLTLSAHWPKNLLVDGEMVKLPFQLQSRLLVHLSGMGL-VVHTSWGLSLTFDGNSFMRLRVPAAYAGTLCGLCGNYNKNPNDDLTAVGGKPEGWKVGGFP-------------DCDQCQLRTCPKPCTPEERKRFGGPNACGIITAPEGPLAPC--HSFVPPTQYFEACLLDTCQVQGHSGG----LCPAIATYVAACQDARVRLREWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETIC-----REGCVCDAGFVLSGDTCVPVGQCGCLH 1973 HSP 4 Score: 97.8265 bits (242), Expect = 3.746e-19 Identity = 88/353 (24.93%), Postives = 156/353 (44.19%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLT----QHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ--KGVLKVNGQLSRVPYEK-SDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAK--KHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHY + D ++ +F G C Y T QH D F + ++NE RG ++ ++ +SV + E+ + +G + V+G L +P++ + +F+ K+ + S+ V+++ D++ +V Y + G+CG+ NG RDD + + + R+ G + VS H D + +C D+ + L + ++C + + F C R + + + +C D C R K C+ + +C +G WR++ CP+ C ++H+ CP TC + G CY E C C+ GY+ G CV C C+
Sbjct: 448 CRASGDPHYMSLDERIFNFMGTCTYLFTASCGQHPSLPD---FKVFIENERRG-SQSVSFVRSVKLEALGIKLEVRREYQGKVLVDGILHYLPFQALGGKLVVFRQGKY-AILRTNFSLSVSYNWDTHVTAKVPSNYFNSVCGLCGNFNGDPRDDLGKQIRAEAIDPRD----FGKKWLVSS---HLGCRTDEQH--LC-PDFNKGLVSNITQNCRIFTNISGHFKHCWRVPAYN--SAYIECAYDCC----RMPGQTKPLCDTLATYTAICQSSGVIVYPWRTETLCPMTCPPHSHYELCQRGCPLTCGDQPVPGGCGSDCY-----ESCVCDEGYVLSGEACVPLASCGCV 774 HSP 5 Score: 87.0409 bits (214), Expect = 6.816e-16 Identity = 76/342 (22.22%), Postives = 138/342 (40.35%), Query Frame = 2
Query: 251 HYRTYDGQVIHFYGDCRYTLTQ-----HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
HY T DG V YG C Y L Q H E +F+I ++ + G+ + T + +V L + + V+ ++ +P ++R F+ + +++ FDGD + + + + ++ G+CG+ NG + DDF SG N G ++ C + +C + + CG + +P PF+ C + ++ +F CV D+C + + C + C AG WR+ CP +C ++H+S + C +C + F G C+ EGC C+ ++ +C+ C C
Sbjct: 2039 HYATPDGLVYDLYGSCSYILAQVCFPKHGEE----AFSIVLEKDLAGNPQRVVVTVA------GQVVVLAKGPQVTVDSEVVALPMVVGSIYITAENRNV--FLQTKSGLKLLFDGDDHILISIPSPFRGRLCGLCGNFNGNQSDDFVLPSGVVAPNVE----AFGAAWRAPGSSLGCGEGCGPQGCPVCSAEKRELYEENDACGKIRDPQGPFAACHKA--LNHSEYFHQCVFDLCTHHGD----RDYLCRSLAAYTAACQAAGAAVKPWRTDSICPAECPAHSHYSICTHSCQGSCAAISGFTGCTTQCF-----EGCECDDHFLLSQGVCIPAQDCGCF 2353 HSP 6 Score: 79.7221 bits (195), Expect = 1.080e-13 Identity = 98/394 (24.87%), Postives = 165/394 (41.88%), Query Frame = 2
Query: 89 TKVEKEPCTNGTRNIRITTYVKDN-GVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLT----QHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVP-YEKSDDVRIFK--SRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLI--GNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVL-LEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVK 1231
T V K+PC T + T KD GVC + N ESK C GDPHY ++DG +F+G C Y + + F++ ++E + D K +Y + V + + + +K G ++VNG +P Y + + S+ L+ ++V ++ V + Y + G+CG+ D ++ + N S+ G S+ V C S + C +D + + CG L + PF+ C +V +FF+ CV+D+C+ + + + C+ + A C AG + WR+Q C + C N+H+ PCP +C T D P EGC C++G++ CV
Sbjct: 1217 TCVTKDPCQGVTCRSQETCTEKDGKGVC-------RANYESK------CWVWGDPHYHSFDGLNTNFHGTCSYLMAGTGCPGTGAEGLTPFSVITKHESQSDPK-VSYVRKVTVKTYNTSITIHEKKTGRVQVNGVFMALPVYLAGGRISVINGGSKAVLET---NFGLQVTYNWKWRVHVTLPSSYYGAVCGLCGNM-----DKNPQNDQVFPNGTMAPSIPTWGGSWQVPGWDPLCWNECQGSCPT-CPEDRVEEYRGPGFCGPLDHDTVGPFTSC--HAHVPPESFFEGCVLDVCLG----GQVKDILCQALADYAAACQAAGIKIEDWRTQAGCEITCPVNSHYELCGPPCPASCPPPARHTAPTACDGPCVEGCQCDKGFVLSADQCVP 1581
BLAST of VWFD domain-containing protein vs. Ensembl Mouse
Match: Zan (zonadhesin [Source:MGI Symbol;Acc:MGI:106656]) HSP 1 Score: 138.658 bits (348), Expect = 1.903e-31 Identity = 109/362 (30.11%), Postives = 155/362 (42.82%), Query Frame = 2
Query: 191 QVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
Q CE K C GD H+ T+D + I F G C Y LTQ F I E RG K VI V + + L + Q +P SDD + S +F++ +RV +DGD FV VS +S K+ G CG+ +G + KS +++ + L S+ V + C+K K+ C ++ K CG L+ P+ PF C ++ +F +CV DMC + Q+ C S + C +AG+ WR CPL C KN+ +S A PCP TC H T + C D EGC C+ G+I G+ CV C C +
Sbjct: 1315 QYQCEPYGKA--TCLVYGDLHFVTFDERHIGFTGTCTYILTQTCSNSTDHFFRITANTEERGVEGVSCLDKVVISLPETTVTMISGRHTL-IGDQEVTLPAILSDDTYVGLSGRFVELRT-TFGLRVRWDGDQQLFVTVSSTFSGKLCGFCGNYDGDSSNDNLKSDGMMTHDEEELRL---SWQVEEDEDKDWVSSRCQKKKNPPS---CDAALGSTMSGPKLCGQLVNPSGPFEACLL--HLKASSFLDNCVTDMCSFQG----LQQKLCAHMSAMTATCQDAGYPVKPWREPQFCPLVCPKNSRYSLCAKPCPETC--HPISTTQHCSDK-CVEGCECDPGFILSGSECVPSSQCGCTSF 1657 HSP 2 Score: 130.183 bits (326), Expect = 5.942e-29 Identity = 121/427 (28.34%), Postives = 174/427 (40.75%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKR-------KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH----NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDC--NGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKC--RKWKQQGQCKEL---SEAMNIICPKTCGFCKA 1375
+C P++ K Q C K + C GDPHY T+DG + HF G C Y LTQ ++E++ F + NE N +Y K+V + +F + GQK VL N Q +P S + + ++V +DG V V Y+ + G+CG+ N + D+ + D+ N L+G ++ + S PG K S C + + KK C +L+ P PFS C V + F CV C C A +C++AG + WR+ CP++C + ++ AN CP TC T R C LP EGC C G+I G CV C C D++ S W + C L S NI C T CKA
Sbjct: 1686 LCKPWKCKAQEACSYKNGVLGCHAQGAATCMVSGDPHYLTFDGALHHFMGTCTYVLTQPCWSKSQENN---FVVSATNEIHDGNLEVSYVKAVHVQVFDLKISMFKGQKVVL--NNQRVVLPVWPSQGRVTIRLSGIFVLLYTNFGLQVRYDGRHLVEVTVPSSYTGSLCGLCGNYNNNSMDDNLRV----DMKPAGNSL-LLGAAWKILEASDPGCFLVGGKP----SRCADSDMDDVWTKK-CAILMNPLGPFSNCHEA--VPPQASFSSCVYGQCETNGD----NLTLCHSLQAYASLCAQAG-QVTTWRNSTFCPMRCPPRSSYNPCANSCPATCLT--LSTPRDCPTLPCVEGCECQSGHILSGTTCVPLRQCG----CSDQDGSYHLLGESWYTEKTCTTLCTCSAHSNITCSPT--ACKA 2082 HSP 3 Score: 117.857 bits (294), Expect = 3.066e-25 Identity = 101/398 (25.38%), Postives = 173/398 (43.47%), Query Frame = 2
Query: 110 CTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRY----TLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRD---DFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDIS-----------YHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CT+G I+ +V +G + +C + + + +C+ GDP+Y T+DG HF G Y T+ + R +P +E +N+ + + I++ ++ +L ++ V+ VN + VPY ++ +R+ + L V + + FDG +A + + Y G+CG N RD + SG SN + GNS+ V + + + S C ++ + + + C VL++P PF+ C + + F Q C++DMC + +++RC + SG A +C EAG WR +C + C N + PCP +C F T + C + P EGCA GYI + HC C
Sbjct: 4873 CTDGV--IQCQNFVCPSGSHCQYNEDGSSDCAANKLE--RCTIFGDPYYLTFDGFTYHFLGRMNYYLIKTVDKLPRGIEP--LIMEGRNKISPKGSSTLHEVTTIVYGYK--IQLQEELVVLVNDEKVAVPYNPNEHLRVMLRAQRLLLVT-DFEMVLDFDGKHSAVISLPTTYRGLTRGLCG--NYDRDQSNELMLPSGVLTSNVH----VYGNSWEVKAQHAFFRFPRALPEEEERDEEPDLLQSECSQEQTALISSTQACRVLVDPQGPFAACHQI--IAPEPFEQRCMLDMCTGW-KTKEEEELRCRVLSGYAIICQEAGANMTGWRDHTHCAMTCPANTVYQRCMTPCPASCAK--FVTPKVC-EGPCVEGCASLPGYIYSDTQSLPVTHCGC 5249 HSP 4 Score: 58.9214 bits (141), Expect = 2.159e-7 Identity = 81/391 (20.72%), Postives = 146/391 (37.34%), Query Frame = 2
Query: 143 TYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYR--GDNKYF-TYTKSVIIHMFREVYELGQKGVLK-VNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDD-FKTKSG-------------RDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE--REGCACNRGYIRDGALCVKPMHCKC 1249
T K N VC R + + C ++ + C D ++D C Y L + H + P F I + + G NK F Y + I F + ++ +N + +P + V + ++V F+ ++ V++ + K+ G+CG+ NG +D T SG +D S N + G + V + K + I + KA+ +C L+ ++ C+ + V ++ F C+ C + + C+ + C G + WR+ CPL+C ++H++ CP +C + + + +P REGC C Y+ CV HC C
Sbjct: 2078 TACKANHVC--LRQEGLLRCAAEMGE---CRISEDSQIVSFDDHSHPIQDTCTYILVKVCHPNTNMP-FFMISAKTDINTNGKNKTFGVYQLYIDIFNFHITLQKDHLVLISLINDSIVTLPTTTHIPGVSVMTEDVYTIVTIKDEIQVKFESNNFLDVKIPASSNGKVCGVCGNFNGEEEDELMTPSGELAEDEQEFMNSWKDKSMDPNCQKIEGQNLQVEQQEIMNGKCRPIDFE-----------KAQANCQTALQ-GPAWAHCSSR--VPIKPFLLKCMNSFCEFR----ELFRALCDSLQSFEDACQNQGLKPPIWRNSSFCPLECPAHSHYTNCLPSCPPSCLDPDSRCEGSGHKVPATCREGCICQPDYVLLNDKCVLRSHCGC 2444
BLAST of VWFD domain-containing protein vs. Ensembl Mouse
Match: Zan (zonadhesin [Source:MGI Symbol;Acc:MGI:106656]) HSP 1 Score: 138.658 bits (348), Expect = 1.903e-31 Identity = 109/362 (30.11%), Postives = 155/362 (42.82%), Query Frame = 2
Query: 191 QVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
Q CE K C GD H+ T+D + I F G C Y LTQ F I E RG K VI V + + L + Q +P SDD + S +F++ +RV +DGD FV VS +S K+ G CG+ +G + KS +++ + L S+ V + C+K K+ C ++ K CG L+ P+ PF C ++ +F +CV DMC + Q+ C S + C +AG+ WR CPL C KN+ +S A PCP TC H T + C D EGC C+ G+I G+ CV C C +
Sbjct: 1315 QYQCEPYGKA--TCLVYGDLHFVTFDERHIGFTGTCTYILTQTCSNSTDHFFRITANTEERGVEGVSCLDKVVISLPETTVTMISGRHTL-IGDQEVTLPAILSDDTYVGLSGRFVELRT-TFGLRVRWDGDQQLFVTVSSTFSGKLCGFCGNYDGDSSNDNLKSDGMMTHDEEELRL---SWQVEEDEDKDWVSSRCQKKKNPPS---CDAALGSTMSGPKLCGQLVNPSGPFEACLL--HLKASSFLDNCVTDMCSFQG----LQQKLCAHMSAMTATCQDAGYPVKPWREPQFCPLVCPKNSRYSLCAKPCPETC--HPISTTQHCSDK-CVEGCECDPGFILSGSECVPSSQCGCTSF 1657 HSP 2 Score: 130.183 bits (326), Expect = 5.942e-29 Identity = 121/427 (28.34%), Postives = 174/427 (40.75%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKR-------KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH----NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDC--NGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKC--RKWKQQGQCKEL---SEAMNIICPKTCGFCKA 1375
+C P++ K Q C K + C GDPHY T+DG + HF G C Y LTQ ++E++ F + NE N +Y K+V + +F + GQK VL N Q +P S + + ++V +DG V V Y+ + G+CG+ N + D+ + D+ N L+G ++ + S PG K S C + + KK C +L+ P PFS C V + F CV C C A +C++AG + WR+ CP++C + ++ AN CP TC T R C LP EGC C G+I G CV C C D++ S W + C L S NI C T CKA
Sbjct: 1686 LCKPWKCKAQEACSYKNGVLGCHAQGAATCMVSGDPHYLTFDGALHHFMGTCTYVLTQPCWSKSQENN---FVVSATNEIHDGNLEVSYVKAVHVQVFDLKISMFKGQKVVL--NNQRVVLPVWPSQGRVTIRLSGIFVLLYTNFGLQVRYDGRHLVEVTVPSSYTGSLCGLCGNYNNNSMDDNLRV----DMKPAGNSL-LLGAAWKILEASDPGCFLVGGKP----SRCADSDMDDVWTKK-CAILMNPLGPFSNCHEA--VPPQASFSSCVYGQCETNGD----NLTLCHSLQAYASLCAQAG-QVTTWRNSTFCPMRCPPRSSYNPCANSCPATCLT--LSTPRDCPTLPCVEGCECQSGHILSGTTCVPLRQCG----CSDQDGSYHLLGESWYTEKTCTTLCTCSAHSNITCSPT--ACKA 2082 HSP 3 Score: 117.857 bits (294), Expect = 3.066e-25 Identity = 101/398 (25.38%), Postives = 173/398 (43.47%), Query Frame = 2
Query: 110 CTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRY----TLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRD---DFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDIS-----------YHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CT+G I+ +V +G + +C + + + +C+ GDP+Y T+DG HF G Y T+ + R +P +E +N+ + + I++ ++ +L ++ V+ VN + VPY ++ +R+ + L V + + FDG +A + + Y G+CG N RD + SG SN + GNS+ V + + + S C ++ + + + C VL++P PF+ C + + F Q C++DMC + +++RC + SG A +C EAG WR +C + C N + PCP +C F T + C + P EGCA GYI + HC C
Sbjct: 4873 CTDGV--IQCQNFVCPSGSHCQYNEDGSSDCAANKLE--RCTIFGDPYYLTFDGFTYHFLGRMNYYLIKTVDKLPRGIEP--LIMEGRNKISPKGSSTLHEVTTIVYGYK--IQLQEELVVLVNDEKVAVPYNPNEHLRVMLRAQRLLLVT-DFEMVLDFDGKHSAVISLPTTYRGLTRGLCG--NYDRDQSNELMLPSGVLTSNVH----VYGNSWEVKAQHAFFRFPRALPEEEERDEEPDLLQSECSQEQTALISSTQACRVLVDPQGPFAACHQI--IAPEPFEQRCMLDMCTGW-KTKEEEELRCRVLSGYAIICQEAGANMTGWRDHTHCAMTCPANTVYQRCMTPCPASCAK--FVTPKVC-EGPCVEGCASLPGYIYSDTQSLPVTHCGC 5249 HSP 4 Score: 58.9214 bits (141), Expect = 2.159e-7 Identity = 81/391 (20.72%), Postives = 146/391 (37.34%), Query Frame = 2
Query: 143 TYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYR--GDNKYF-TYTKSVIIHMFREVYELGQKGVLK-VNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDD-FKTKSG-------------RDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE--REGCACNRGYIRDGALCVKPMHCKC 1249
T K N VC R + + C ++ + C D ++D C Y L + H + P F I + + G NK F Y + I F + ++ +N + +P + V + ++V F+ ++ V++ + K+ G+CG+ NG +D T SG +D S N + G + V + K + I + KA+ +C L+ ++ C+ + V ++ F C+ C + + C+ + C G + WR+ CPL+C ++H++ CP +C + + + +P REGC C Y+ CV HC C
Sbjct: 2078 TACKANHVC--LRQEGLLRCAAEMGE---CRISEDSQIVSFDDHSHPIQDTCTYILVKVCHPNTNMP-FFMISAKTDINTNGKNKTFGVYQLYIDIFNFHITLQKDHLVLISLINDSIVTLPTTTHIPGVSVMTEDVYTIVTIKDEIQVKFESNNFLDVKIPASSNGKVCGVCGNFNGEEEDELMTPSGELAEDEQEFMNSWKDKSMDPNCQKIEGQNLQVEQQEIMNGKCRPIDFE-----------KAQANCQTALQ-GPAWAHCSSR--VPIKPFLLKCMNSFCEFR----ELFRALCDSLQSFEDACQNQGLKPPIWRNSSFCPLECPAHSHYTNCLPSCPPSCLDPDSRCEGSGHKVPATCREGCICQPDYVLLNDKCVLRSHCGC 2444
BLAST of VWFD domain-containing protein vs. Ensembl Mouse
Match: Fcgbp (Fc fragment of IgG binding protein [Source:MGI Symbol;Acc:MGI:2444336]) HSP 1 Score: 128.642 bits (322), Expect = 1.544e-28 Identity = 100/346 (28.90%), Postives = 157/346 (45.38%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHY T+DG+ G C YT+ + D+ +F++E +NE+RG ++ +Y V ++ + L G+ G ++++ Q SR+P S+ +R+ KS + + V +D D + + KR+ ++ G+CG+ NG DDF T D+ + NS+ + + C S S C + K + CG+L PFS C +D + F DCV D+CV + C S A+ C E G WR +CP+ C N+ + + CP +C + T C P EGC C G++ G CV C CI
Sbjct: 56 CRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGSDETLPAFSVEAKNEHRG-SRQVSYVGLVTVYAYSHSVSLVRGEIGFVRIDNQRSRLPASLSEGRLRVHKSGT-RGVIEMDFGLVVTYDWDGQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTP---DLDQAPDALEF-ANSWKLDDGDYLCDDGCHNSCPS-CTPGQTQHYKGDRLCGMLTLSTGPFSACHE--FLDPKPFLDDCVFDLCVTGGE----RLSLCRSLSAYAQACVELGVTLENWRLPASCPMSCPANSCYDPCSPACPPSCNSEAVPTN--CSSRPCVEGCVCLPGFVASGGDCVPVSSCGCI 386 HSP 2 Score: 120.939 bits (302), Expect = 3.261e-26 Identity = 105/372 (28.23%), Postives = 162/372 (43.55%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ-KGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKH----CGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE--REGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQC 1315
C A GDPHY T+DG+ F G C Y L Q F + +NE G+ K + TK + + + L Q + +KVNG +++P +R+ + + + +RVA+D V + Y K+M G+CGD NG +DDF+ G ++ + GNS+ + P C + C + L+ K H CG+L P P + C + +D + QDCV D+C+ Q + C I C AG + WR++ CP++C ++H+ A+ C C T + C PE EGC C+ G++ +G CV C C + V E E Q C
Sbjct: 836 CQASGDPHYVTFDGRRFDFMGTCVYVLAQTCGNRPGLHQFTVLQENEAWGNGK-VSVTKVITVLVANYTLRLEQSQWKVKVNGVDTKLPVMLDGGKIRVSQHGSDV-VIETDFGLRVAYDLVYYVRVTIPGNYYKQMCGLCGDYNGDPKDDFQKPDGSQTTDPSD----FGNSWEEAVPDSPCAPVPPCTGDD-CDTECSPELQDKYHGEQFCGLLTSPTGPLAACHKL--LDPQGPLQDCVFDLCLGGGN----QSILCNIIHAYVSACQAAGGQVEPWRTETFCPMECPPHSHYEVCADTCSLGCWA--LNTPQQC---PEGCAEGCECDSGFLYNGKACVPIEQCGCYHNGVYYEPEESVLIENCQQHC 1189 HSP 3 Score: 120.168 bits (300), Expect = 5.966e-26 Identity = 96/348 (27.59%), Postives = 151/348 (43.39%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHF--FGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+C A GDPHY T DG F G C Y L+ H FN+ V NE+RG ++ +YT+SV + ++ L + L+VNG+ +P+ + ++ S + V V +AFDGDS + V Y+ + G+CG+ N +D T G K + + G PG C + + C + + CG++ P P + C V +F+ C++D C + P C + C AG + +WR CPLQC ++H+ + CP +C + G + C REGC C+ G++ G CV C C+
Sbjct: 1651 ECQAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHEPPTGTEYFNVTVANEHRG-SQAVSYTRSVTLQIYGLSLTLSAQWPRKLQVNGEFVALPFHLDQKLSVYISGADV-VVNTASGVSLAFDGDSFVRLRVPAAYAGTLCGLCGNYNKNPNDDLTAVG----GKPEGWKVGG------APG--CDQCEPEPCPKPCTPEEQEPFRGPDACGIITAPEGPLAPC--HSLVPPTQYFEACLLDACQVQGHPGGL----CPAIATYVAACQAAGAQLGEWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETIC-----REGCVCDAGFVLSGDTCVPVGQCGCL 1973 HSP 4 Score: 115.546 bits (288), Expect = 1.398e-24 Identity = 99/361 (27.42%), Postives = 166/361 (45.98%), Query Frame = 2
Query: 218 DFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-SFNIEVQNEYRGDNKYFTYTKSV--IIHMFREVYELGQKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYH--------VSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
+F C A GDPHY ++DG+ F G C Y L ++ +F + V+NE+RG ++ +YT++V + H G + ++G L +P++ + +++++ V+ + V ++ D++ +V Y+K + G+CG+ NG DD K G SN + GNS+ ++PG C + + I + KK CG+L +P PF +C + N + +DCV D+C+ + C+ + A C AG WRS+ CPL C N+H+ + + CP +C + G C REGC CN G+ G CV C C++
Sbjct: 444 NFASCQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQNAALPAFKVLVENEHRG-SQTVSYTRAVRVVAHGVEVAVRRENPGRVLIDGVLQYLPFQAAGGKIQVYRQGND-AIVSIDFGLTVTYNWDAHVTAKVPSSYAKDVCGLCGNFNGNPDDDLALKGGGQASNVLD----FGNSWQEEIIPGCGATEPGD-CPQLDSLVTQQI---------QDKKECGILADPEGPFRECHKLLNP--QGAIRDCVYDLCLLPGQSGPL----CDALAAYAAACQAAGGTVHPWRSEELCPLTCPPNSHYEQCSYGCPLSCGDLPVQGGCGSEC-----REGCVCNEGFALSGESCVPLASCGCVH 777 HSP 5 Score: 85.5001 bits (210), Expect = 1.881e-15 Identity = 95/410 (23.17%), Postives = 163/410 (39.76%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCE--NHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI---------NLCVDRESSEKCRKWKQQG-QCKELSEAMNIICPKTCGF--CKATAGHCEDELSA 1408
C A G HY T DG+V +G C Y L H + D F+I ++ GD + T + +V L + + V+G++ +P + R + + ++V FDGD++ + + + ++ G+CG+ NG DDF SG N G ++ C + +C + ++ + CG + +P+ PF+ C + + +F+ CV DMC +K + C + C AG WR+ CPLQC ++H+S C +C + G C+ EGC C+ ++ +C+ C C+ + + + SE+C G C E +C G C+A G C + A
Sbjct: 2034 CLANGGLHYVTLDGRVYDLHGSCSYVLASVCHPKPGDE-EFSIVLEKNSAGDPQRVVVTVAG------QVVGLARGPQVTVDGEVVTLPVATGHVSVTAEGRNIV--LQTNKGMKVLFDGDAHILMSIPSSFRGRLCGLCGNFNGNWSDDFVLPSGAVAPN----VEAFGTAWRAPGSSLGCGEGCGPQGCPVCLAEETQAYEKNDACGKIRDPHGPFAACHKV--LSPLEYFRQCVYDMCAHKGD----KAYLCRSLAAYTAACQAAGAAVKPWRTDSVCPLQCPAHSHYSICTRSCQGSCAALSGLTGCTTRCF-----EGCECDDHFLLSHGVCIPAQDCGCVHNGQYMPVNSSLMSSDCSERCFCSPNNGLTCHEAGCPSGHVCEIQAGVRECQAARGLCSISVGA 2419 HSP 6 Score: 67.0106 bits (162), Expect = 7.507e-10 Identity = 100/404 (24.75%), Postives = 163/404 (40.35%), Query Frame = 2
Query: 89 TKVEKEPCTNGTRNIRITTYVKD-NGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRY----TLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVP-YEKSDDVRIFK--SRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPG------HHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLE-PNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
T V K+PC T + T V+ GVC P T C GDPHY ++DG F G C Y TL + F + +NE RG + +Y + V + + + G ++VNG L +P Y + + S+ L+ ++V +D + V + Y + G+CG+ + + + ++ + G S+ V PG H C+ + C +D + + CG L +PF+ C +V +FF+ CV+D+C+ + + C+ + A C AG + WR+Q C + C N+H+ PCP +C T D P EGC C+ G++ CV P+ C
Sbjct: 1218 TCVTKDPCHGITCRPQETCKVQGGEGVCVPNYNST-------------CWLWGDPHYNSFDGWSFDFQGTCNYLLAGTLCPGVNAEGLTPFTVTTKNENRG-SPAVSYVRQVTVTTLNTNISIHKNEIGKVRVNGVLMALPVYLAGGRISVINGGSKAVLE---TDFGLQVTYDWNWRVDVTLPSSYHGAVCGLCGNMDKNHQNDQVFPNGTMAPSIPTW---GGSWQV--PGWDPLCWHECQGS-----CPTCPEDRVEEYEGPGFCGPLAPGTGSPFTSC--HAHVPPESFFKGCVLDVCLGGGS----KDILCQALAAYAAACQAAGIKIEDWRTQAGCEITCPDNSHYELCGPPCPASCPPPARHTAPTVCDGPCVEGCQCDEGFVLSADQCV-PLDGGC 1587
BLAST of VWFD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q28983|ZAN_PIG (Zonadhesin OS=Sus scrofa OX=9823 GN=ZAN PE=1 SV=1) HSP 1 Score: 142.51 bits (358), Expect = 7.037e-32 Identity = 112/390 (28.72%), Postives = 175/390 (44.87%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKR--KDFCK------CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYF-----TYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRI-FKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYH------------SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C PF + CE KDFC+ CS GDPHYRT+DG F G YTL + D +E G NK + + + +I+ ++ +L + L VNGQ +PY+ ++ +++ + R+ ++ + V+F+G +NA + + Y + G+CG+ + R+DF +G N + GNS+ V H + ++ I S C + + + + CGVL++P PF+ C + V F + CV D+C P +++RC++ SG A +C E+G WR +C L C N + PCP +C R C D P EGCA GYI GA + HC C N
Sbjct: 1941 CRPFTCPSGSQCEPNEDGKDFCQPNSSNLCSVFGDPHYRTFDGLSYRFQGRMTYTLV---KTLDVLPDGVEPL-VVEGRNKVYPSLTPVFLQEIIVMVYGYTVQLQAELELVVNGQKVSIPYKPNEYLQVTLRGRRL--YLVTDFELVVSFNGRNNAVIAMPSTYLGLVRGLCGNYDKNKRNDFMLPNGSFTQN----LLVFGNSWEVKAKEGHPRFSRAIREEEEKNEESGFQNVSECSPEQLELVNHTQACGVLVDPQGPFAACHQI--VAPGPFQEHCVFDLCAAPG-PKEQEELRCQVLSGYAIICQESGPTLAGWRDHTHCALPCPANTVYQSCMTPCPASCAT--LAVPRAC-DGPCVEGCASLPGYIYSGAQSLPMAHCGCTN 2314 HSP 2 Score: 141.354 bits (355), Expect = 1.424e-31 Identity = 112/376 (29.79%), Postives = 166/376 (44.15%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS------FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C F+ T C+ K + CS GDPHY T+DG+ +F G C Y L Q PC F + V+ E RG +K + V L + L V GQ +P S V + S +F++ + +RV +DGD FV V +S K+ G+CGD +G D D S +++ L G+S+ S+ + +S S C ++ + CG L+ P+ F C ++ +FF+ C DMC + Q + C S L E C +AG+ WR CPL C +N+ ++ A CP TC + F G R C D EGC C+ G++ G CV C C++
Sbjct: 773 CQTFKCGTHTVCQLKNGQYGCHPYGSATCSVYGDPHYLTFDGRRFNFMGKCTYILAQ------PCGNLTEHFFRVLVKKEERGQEGVSCLSKVYVTLPESTVTLLKGRHTL-VGGQRVTLPAIPSRGVFLAPSGRFVE-LQTAFGLRVRWDGDQQLFVSVPSTFSGKLCGLCGDYDG--DSSNDNQKPDGSPAKDEKEL-GSSWQTSEDADQQCEENQVSPPS-CNTALQNTMSGPEFCGQLVAPHGVFEACLP--HLRASSFFKSCTFDMCNFQG----LQHMLCAHMSALTENCQDAGYTVKPWRGPQFCPLACPRNSRYTLCARLCPDTCHSEFSG--RACKDRCV-EGCECDPGFVLSGLQCVSRSECGCLD 1127 HSP 3 Score: 136.346 bits (342), Expect = 4.637e-30 Identity = 108/355 (30.42%), Postives = 161/355 (45.35%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-------SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVP-YEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY---DLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+ GDPHY T+DG + HF G C YTLT+ PC SF + NE+RG N +Y ++V + +F L + + ++G+ +P + V I S F+ + ++V +DGD V V Y+ ++ G+CG+ N DD R S+ +G S+ + S+PG + K GK+ + +K+C VL+ P PFS+C R V ++ F C+ C K C A +C+ AG + + WR+ CPL+C + +S ANPCP TC P Y LP EGC C +G+I G CV C C
Sbjct: 1186 CTVSGDPHYLTFDGALHHFTGTCTYTLTK------PCWLRSLENSFLVSATNEFRGGNLEASYVRAVQVQVFNLRISLIKGRKVTLDGRRVALPLWPAQGRVSITSSGSFI-LLYTDFGLQVRYDGDHLVEVTVPSSYAGRLCGLCGNYNNNSLDDILQPDKRPASSSVR----LGASWKINELSEPGCFAEGGKP---PRCLGKEVADAW--RKNCDVLMNPQGPFSQCHRV--VAPQSSFSSCLYGQCATKGD----TLTLCRSLQAYASLCARAG-QALTWRNGTFCPLKCPSGSSYSTCANPCPATC----LSLNNPSYCPSTLPCAEGCECQKGHILSGTSCVPLSQCGC 1513
BLAST of VWFD domain-containing protein vs. UniProt/SwissProt
Match: sp|O88799|ZAN_MOUSE (Zonadhesin OS=Mus musculus OX=10090 GN=Zan PE=1 SV=1) HSP 1 Score: 138.658 bits (348), Expect = 1.264e-30 Identity = 109/362 (30.11%), Postives = 155/362 (42.82%), Query Frame = 2
Query: 191 QVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKP------GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
Q CE K C GD H+ T+D + I F G C Y LTQ F I E RG K VI V + + L + Q +P SDD + S +F++ +RV +DGD FV VS +S K+ G CG+ +G + KS +++ + L S+ V + C+K K+ C ++ K CG L+ P+ PF C ++ +F +CV DMC + Q+ C S + C +AG+ WR CPL C KN+ +S A PCP TC H T + C D EGC C+ G+I G+ CV C C +
Sbjct: 1271 QYQCEPYGKA--TCLVYGDLHFVTFDERHIGFTGTCTYILTQTCSNSTDHFFRITANTEERGVEGVSCLDKVVISLPETTVTMISGRHTL-IGDQEVTLPAILSDDTYVGLSGRFVELRT-TFGLRVRWDGDQQLFVTVSSTFSGKLCGFCGNYDGDSSNDNLKSDGMMTHDEEELRL---SWQVEEDEDKDWVSSRCQKKKNPPS---CDAALGSTMSGPKLCGQLVNPSGPFEACLL--HLKASSFLDNCVTDMCSFQG----LQQKLCARMSAMTATCQDAGYPVKPWREPQFCPLVCPKNSRYSLCAKPCPETC--HPISTTQHCSDK-CVEGCECDPGFILSGSECVPSSQCGCTSF 1613 HSP 2 Score: 131.724 bits (330), Expect = 1.470e-28 Identity = 121/425 (28.47%), Postives = 173/425 (40.71%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKR-------KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH----NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKC--RKWKQQGQCKEL---SEAMNIICPKTCGFCKA 1375
+C P++ K Q C K + C GDPHY T+DG + HF G C Y LTQ ++E++ F + NE N +Y K+V + +F + GQK VL N Q +P S + + ++V +DG V V Y+ + G+CG+ N D ++ D+ N L+G ++ + S PG K S C + + KK C +L+ P PFS C V + F CV C C A +C++AG + WR+ CP++C + ++ AN CP TC T R C LP EGC C G+I G CV C C D++ S W + C L S NI C T CKA
Sbjct: 1642 LCKPWKCKAQEACSYKNGVLGCHAQGAATCMVSGDPHYLTFDGALHHFMGTCTYVLTQPCWSKSQENN---FVVSATNEIHDGNLEVSYVKAVHVQVFDLKISMFKGQKVVL--NNQRVVLPVWPSQGRVTIRLSGIFVLLYTNFGLQVRYDGRHLVEVTVPSSYTGSLCGLCGNYNNNSMDDNLRA--DMKPAGNSL-LLGAAWKILEASDPGCFLAGGKP----SRCADSDMDDVWTKK-CAILMNPLGPFSNCHEA--VPPQASFSSCVYGQCETNGD----NLTFCHSLQAYASLCAQAG-QVTTWRNSTFCPMRCPPRSSYNPCANSCPATCLT--LSTPRDCPTLPCVEGCECQSGHILSGTTCVPLRQCG----CSDQDGSYHLLGESWYTEKTCTTLCTCSAHSNITCSPT--ACKA 2038 HSP 3 Score: 119.013 bits (297), Expect = 1.182e-24 Identity = 101/398 (25.38%), Postives = 173/398 (43.47%), Query Frame = 2
Query: 110 CTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRY----TLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRD---DFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDIS-----------YHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CT+G I+ +V +G + +C + + + +C+ GDP+Y T+DG HF G Y T+ + R +P +E +N+ + + I++ ++ +L ++ V+ VN + VPY ++ +R+ + L V + + FDG +A + + Y G+CG N RD + SG SN + GNS+ V + + + S C ++ + + + C VL++P PF+ C + + F Q C++DMC + +++RC + SG A +C EAG WR +C + C N + PCP +C F T + C + P EGCA GYI + HC C
Sbjct: 4829 CTDGV--IQCQNFVCPSGSHCQYNEDGSSDCAANKLE--RCTIFGDPYYLTFDGFTYHFLGRMNYYLIKTVDKLPRGIEP--LIMEGRNKISPKGSSTLHEVTTIVYGYK--IQLQEELVVLVNDEKVAVPYNPNEHLRVMLRAQRLLLVT-DFEMVLDFDGKHSAVISLPTTYRGLTRGLCG--NYDRDQSNELMLPSGVLTSNVH----VFGNSWEVKAQHAFFRFPRALPEDEERDEEPDLLQSECSQEQTALISSTQACRVLVDPQGPFAACHQI--IAPEPFEQRCMLDMCTGW-KTKEEEELRCRVLSGYAIICQEAGANMTGWRDHTHCAMTCPANTVYQRCMTPCPASCAK--FVTPKVC-EGPCVEGCASLPGYIYSDTQSLPVTHCGC 5205 HSP 4 Score: 59.3066 bits (142), Expect = 1.204e-6 Identity = 81/391 (20.72%), Postives = 146/391 (37.34%), Query Frame = 2
Query: 143 TYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYR--GDNKYF-TYTKSVIIHMFREVYELGQKGVLK-VNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDD-FKTKSG-------------RDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE--REGCACNRGYIRDGALCVKPMHCKC 1249
T K N VC R + + C ++ + C D ++D C Y L + H + P F I + + G NK F Y + I F + ++ +N + +P + V + ++V F+ ++ V++ + K+ G+CG+ NG +D T SG +D S N + G + V + K + I + KA+ +C L+ ++ C+ + V ++ F C+ C + + C+ + C G + WR+ CPL+C ++H++ CP +C + + + +P REGC C Y+ CV HC C
Sbjct: 2034 TACKANHVC--LRQEGLLRCAAEMGE---CRISEDSQIVSFDDHSHPIQDTCTYILVKVCHPNTNMP-FFMISAKTDINTNGKNKTFGVYQLYIDIFNFHITLQKDHLVLISLINDSIVTLPTTTHIPGVSVMTEDVYTIVTIKDEIQVKFESNNFLDVKIPASSNGKVCGVCGNFNGEEEDELMTPSGELAEDEQEFMNSWKDKSMDPNCQKIEGQNLQVEQQEIMNGKCRPIDFE-----------KAQANCQTALQ-GPAWAHCSSR--VPIKPFLLKCMNSFCEFR----ELFRALCDSLQSFEDACQNQGLKPPIWRNSSFCPLECPAHSHYTNCLPSCPPSCLDPDSRCEGSGHKVPATCREGCICQPDYVLLNDKCVLRSHCGC 2400
BLAST of VWFD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q6ZWJ8|KCP_HUMAN (Kielin/chordin-like protein OS=Homo sapiens OX=9606 GN=KCP PE=2 SV=3) HSP 1 Score: 137.887 bits (346), Expect = 1.493e-30 Identity = 106/364 (29.12%), Postives = 158/364 (43.41%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRI-FKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK---PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQ----FNCPLQCGKNAHFSEKANPCPRTCENHFFGTK-------RPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDR 1270
C A GDPHYRT+DG+++HF G C Y L + D F++ V N+ RG + +T+ V + + L Q G + V+G +P+ + + + + + P ++V +DG S V V Y + G+CG+ NG +DD + G + ++ + GNS+ VS+ PG C +++ G R A+ CGVL ++PFS+C V FF CV D+C S C+ A C +AG WR CPL+ + F E PCPRTC N RPC GC C G + A C+ P C + L D+
Sbjct: 1214 SCMAFGDPHYRTFDGRLLHFQGSCSYVLAKDCHSGD---FSVHVTNDDRGRSG-VAWTQEVAVLLGDMAVRLLQDGAVTVDGHPVALPFLQEPLLYVELRGHTVILHAQP--GLQVLWDGQSQVEVSVPGSYQGRTCGLCGNFNGFAQDDLQGPEGLLLPSE----AAFGNSWQVSEGLWPGRPCSAGREVDPCRAAGYRARREANAR--CGVLK--SSPFSRC--HAVVPPEPFFAACVYDLCACGPG-SSADACLCDALEAYASHCRQAGVT-PTWRGPTLCVVGCPLE--RGFVFDECGPPCPRTCFNQHIPLGELAAHCVRPCVP-----GCQCPAGLVEHEAHCIPPEACPQVLLTGDQ 1552
BLAST of VWFD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y493|ZAN_HUMAN (Zonadhesin OS=Homo sapiens OX=9606 GN=ZAN PE=2 SV=5) HSP 1 Score: 137.887 bits (346), Expect = 1.719e-30 Identity = 103/344 (29.94%), Postives = 154/344 (44.77%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTK-SGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG+ F G C Y L Q F + +NE +G +K + V L + L V GQ +P S V + S +F++ + +RV +DGD +V VS YS K+ G+CG+ +G D+ K G +K +GNS+ + C+K + ++ S C S+ CG L++ + PF C +V +FF C++DMC + Q + C S + C +AG WR CP+ C N+ +S A PCP TC + F G C D E C CN G++ G C+ C C++
Sbjct: 1156 CLVYGDPHYVTFDGRHFGFMGKCTYILAQPCGNSTDPFFRVTAKNEEQGQEGVSCLSKVYVTLPESTVTLLKGRRTL-VGGQQVTLPAIPSKGVFLGASGRFVE-LQTEFGLRVRWDGDQQLYVTVSSTYSGKLCGLCGNYDGNSDNDHLKLDGSPAGDKEE----LGNSWQTDQDEDQECQKYQVVNSPS-CDSSLQSSMSGPGFCGRLVDTHGPFETCLL--HVKAASFFDSCMLDMCGFQG----LQHLLCTHMSTMTTTCQDAGHAVKPWREPHFCPMACPPNSKYSLCAKPCPDTCHSGFSGMF--CSDRCV-EACECNPGFVLSGLECIPRSQCGCLH 1483 HSP 2 Score: 112.079 bits (279), Expect = 1.299e-22 Identity = 101/374 (27.01%), Postives = 158/374 (42.25%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDF-------CKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKD-WIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPC-YDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C P+R + Q C + + C+A GDPHY T+DG + HF G C Y LT+ +R D F + NE RG +Y K+V + +F L + + +NG +P + + L + ++V +DG V V Y ++ G+CG+ N D + R ++ + S+PG K S D W K+C +L+ P PFS+C + V ++ F CV C K + C A +C++AG + WR++ CP++C + +S ++PCP TC + R C LP E C C +G+I G CV C C +
Sbjct: 1514 CQPWRCRAQEFCGQQDGIYGCHAQGAATCTASGDPHYLTFDGALHHFMGTCTYVLTRPCWSRSQDS-YFVVSATNENRGGILEVSYIKAVHVTVFDLSISLLRGCKVMLNGHRVALPVWLAQGRVTIRLSSNLVLLYTNFGLQVRYDGSHLVEVTVPSSYGGQLCGLCGNYNNNSLDDNLRPDRKLAGDSMQLGAAWKLPESSEPGCFLVGGKPSSCQENSMADAW------NKNCAILINPQGPFSQCHQV--VPPQSSFASCVHGQCGTKGDTT----ALCRSLQAYASLCAQAG-QAPAWRNRTFCPMRCPPGSSYSPCSSPCPDTCSS--INNPRDCPKALPCAESCECQKGHILSGTSCVPLGQCGCTD 1871 HSP 3 Score: 64.6994 bits (156), Expect = 2.957e-8 Identity = 73/299 (24.41%), Postives = 125/299 (41.81%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIE---VQNEYRGD-NKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSK-----------PGHHCKKAKDISYH-----SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSG 1000
C + NC S + + +CS GDP Y T+DG G Y L + D +E V+ + D + + + VI ++ +L L VN Q VPY ++ +R+ + L V + V+F G NA + + Y ++G+CG+ + R +D SG N + GNS+ V P + ++ S C + + S + + C VL +P PF+ C + V F + CV+D+C ++ P +++RC++ SG
Sbjct: 2312 CQLTSDNSNSNCVSDKSE--QCSVYGDPRYLTFDGFSYRLQGRMTYVLI---KTVDVLPEGVEPLLVEGRNKMDPPRSSIFLQEVITTVYGYKVQLQAGLELVVNNQKMAVPYRPNEHLRVTLWGQRLYLVTD-FELVVSFGGRKNAVISLPSMYEGLVSGLCGNYDKNRKNDMMLPSGALTQN----LNTFGNSWEVKTEDALLRFPRAIPAEEEGQGAELGLRTGLQVSECSPEQLAS-NSTQACRVLADPQGPFAACHQ--TVAPEPFQEHCVLDLCSAQD-PREQEELRCQVLSG 2596
BLAST of VWFD domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9Y6R7|FCGBP_HUMAN (IgGFc-binding protein OS=Homo sapiens OX=9606 GN=FCGBP PE=1 SV=3) HSP 1 Score: 131.724 bits (330), Expect = 1.471e-28 Identity = 102/353 (28.90%), Postives = 157/353 (44.48%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVR------VAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRP--CYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+DG+ G C YT+ + EDD +F++E +NE+RG + +Y V + + L G+ G + V+ Q SR+P S+ +R+++S PR V V +D D + + R+ ++ G+CG+ NG DDF T G + +S+ + + C+ + + C + + + CG+L + + PF+ C +D R F + CV D+CV + C S A+ C E G WRS NCPL C N+ + CP +C G P C P EGC C G++ G CV C C
Sbjct: 472 CRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRR-VSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQS-------GPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVE----FASSWKLDDGDYLCEDGCQNNCPA-CTPGQAQHYEGDRLCGMLTKLDGPFAVC--HDTLDPRPFLEQCVYDLCVVGGE----RLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCN----GAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGC 801 HSP 2 Score: 119.398 bits (298), Expect = 7.591e-25 Identity = 100/354 (28.25%), Postives = 150/354 (42.37%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE------REGCACNRGYIRDGALCVKPMHCKCIN 1255
+C A GDPHY T DG F G C Y L+ H +F + V NE+RG ++ +YT+SV + ++ L + L+V+G +P++ + S + V + +AFDGDS + V Y+ + G+CG+ N DD K G+ + G VSKP C S C + S CGV+ + P + C G V +FQ C++D C + P C + C AG + +WR CPLQC ++H+ + CP +C P PE REGC C+ G++ G CV C C++
Sbjct: 4473 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADV-VVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKP---CP--------SPCTPEQQESFGGPDACGVISATDGPLAPC--HGLVPPAQYFQGCLLDACQVQGHPGGL----CPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSC---------PSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH 4796 HSP 3 Score: 119.013 bits (297), Expect = 1.088e-24 Identity = 99/354 (27.97%), Postives = 150/354 (42.37%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE------REGCACNRGYIRDGALCVKPMHCKCIN 1255
+C A GDPHY T DG +F G C Y L+ H +F + V NE+RG ++ +YT+SV + ++ L + L+V+G +P++ + S + V + +AFDGDS + V Y+ + G+CG+ N DD K G+ + G VSKP C S C + S CGV+ + P + C G V +FQ C++D C + P C + C AG + +WR CP QC ++H+ + CP +C P PE REGC C+ G++ G CV C C++
Sbjct: 2071 ECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADV-VVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKP---CP--------SPCTPEQQESFGGPDACGVISATDGPLAPC--HGLVPPAQYFQGCLLDACQVQGHPGGL----CPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSC---------PSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH 2394 HSP 4 Score: 118.242 bits (295), Expect = 1.724e-24 Identity = 99/354 (27.97%), Postives = 149/354 (42.09%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE------REGCACNRGYIRDGALCVKPMHCKCIN 1255
+C A GDPHY T DG F G C Y L+ H +F + V NE+RG ++ +YT+SV + ++ L + L+V+G +P++ + S + V + +AFDGDS + V Y+ + G+CG+ N DD K G+ + G VSKP C S C + S CGV+ + P + C G V +FQ C++D C + P C + C AG + +WR CP QC ++H+ + CP +C P PE REGC C+ G++ G CV C C++
Sbjct: 3272 ECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRG-SQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADV-VVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGEC--VSKP---CP--------SPCTPEQQESFGGPDACGVISATDGPLAPC--HGLVPPAQYFQGCLLDACQVQGHPGGL----CPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSC---------PSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLH 3595 HSP 5 Score: 106.686 bits (265), Expect = 5.075e-21 Identity = 90/349 (25.79%), Postives = 141/349 (40.40%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKG-VLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK-------AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+DG+ F G C Y L Q +Q N + T+ + + + L Q+ + VNG ++P ++ + +RVA+D V V Y ++M G+CG+ NG +DDF+ +G N GNS+ P C ++D C + + + ++ CG+L P P S C + VD + +DC+ D+C+ S + C C AG WR++ CP++C N+H+ A+ C C C D EGC C+ G++ +G CV C C
Sbjct: 1252 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANE----FGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKL--VDPQGPLKDCIFDLCLGGGNLS----ILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSA--LSAPPQCQD-GCAEGCQCDSGFLYNGQACVPIQQCGC 1587 HSP 6 Score: 106.301 bits (264), Expect = 7.459e-21 Identity = 94/354 (26.55%), Postives = 163/354 (46.05%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC-SFNIEVQNEYRGDNKYFTYTKSVIIHM--FREVYELGQKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDI-SYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
F C GDPHY ++DG+ F G C Y L ++ +F + V+NE+RG ++ +YT++V + + G + V+ L +P++ +D V++F+ + V + V +D ++ +V Y++ + G+CG+ NG DD + G +N GNS+ ++PG + D S+ + L++K CG+L +P PF +C K +D + +DCV D C+ + C+ + A C AG WRS+ CPL C ++H+ + CP +C + G C+ EGC C+ G+ G C+ C C++
Sbjct: 861 FGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRG-SQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRD-AVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANAL----AFGNSWQEETRPGCGATEPGDCPKLDSLVAQ----QLQSKNECGILADPKGPFRECHSK--LDPQGAVRDCVYDRCLLPGQSGPL----CDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECH-----EGCVCDEGFALSGESCLPLASCGCVH 1193 HSP 7 Score: 104.76 bits (260), Expect = 2.470e-20 Identity = 90/349 (25.79%), Postives = 140/349 (40.11%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKG-VLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS-------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+DG+ F G C Y L Q +Q N + T+ + + + L Q+ + VNG ++P ++ + +RVA+D V V Y + M G+CG+ NG +DDF+ +G N GNS+ P C S C + + + ++ CG+L P P S C + VD + +DC+ D+C+ S + C C AG + WR++ CP++C +N+H+ A+ C C C D EGC C+ G++ +G CV C C
Sbjct: 2453 CQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE----FGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKL--VDPQGPLKDCIFDLCLGGGNLS----ILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSA--LSAPLQCPD-GCAEGCQCDSGFLYNGQACVPIQQCGC 2788 HSP 8 Score: 104.375 bits (259), Expect = 2.920e-20 Identity = 90/349 (25.79%), Postives = 138/349 (39.54%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKG-VLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSI-------CGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+DG F G C Y L Q +Q N + T+ + + + L Q+ + VNG ++P ++ + +RVA+D V V Y + M G+CG+ NG +DDF+ +G N GNS+ P C S C + + + ++ CG+L P P S C + VD + +DC+ D+C+ S + C C AG WR++ CP++C +N+H+ A+ C C C D EGC C+ G++ +G CV C C
Sbjct: 3654 CQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANE----FGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKL--VDPQGPLKDCIFDLCLGGGNLS----ILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSA--LSAPLQCPD-GCAEGCQCDSGFLYNGQACVPIQQCGC 3989 HSP 9 Score: 93.5893 bits (231), Expect = 5.330e-17 Identity = 84/350 (24.00%), Postives = 145/350 (41.43%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENH------FFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+C A G HY T DG+V +G C Y L Q H + D F+I ++ GD + +++ + +V L Q + V+G+ +P VR+ + + + +R+ FDGD++ + + + ++ G+CG+ NG DDF +G S+ G ++ C + +C + ++ + CG L P PF+ C + + +F+ CV D+C K + C + C AG WR+ CPL C ++H+S C RTC+ G C+ EGC C+ ++ +C+ C C
Sbjct: 4855 RCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDE-DFSIVLEKNAAGD------LQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGR-VRVTAEGRNMVLQTTK-GLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVET----FGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATC--QAVLSPSEYFRQCVYDLCAQKGD----KAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYS----ICTRTCQGSCAALSGLTGCTTRCF-----EGCECDDRFLLSQGVCIPVQDCGC 5176 HSP 10 Score: 88.5817 bits (218), Expect = 1.779e-15 Identity = 101/441 (22.90%), Postives = 171/441 (38.78%), Query Frame = 2
Query: 95 VEKEPCTNGT-RNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHN----REDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLE-PNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMH--CKC-INLCVDRESSE-----KCRKWKQQGQCKELSEAMNIIC-PKTCGF 1366
V K+PC T R GVC P T C GDPHY ++DG+ F G C Y L F + +N+ RG N +Y + V + + + G ++VNG L+ +P +D + ++V++D + V + Y + G+CG+ + ++ + ++ + G S+ C S + C +D + + CG L PF+ C +V +FF+ CV+D+C+ + + C+ + C AG WR+Q C + C +N+H+ +PCP +C + T + P EGC C+ G++ CV P++ C C N SE C +W C+ +++C P +CG
Sbjct: 1640 VTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT-------------CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGPGFCGPLAPGTGGPFTTC--HAHVPPESFFKGCVLDVCMGGGD----RDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV-PLNNGCGCWANGTYHEAGSEFWADGTCSQW-----CRCGPGGGSLVCTPASCGL 2050 HSP 11 Score: 73.9442 bits (180), Expect = 4.930e-11 Identity = 101/441 (22.90%), Postives = 170/441 (38.55%), Query Frame = 2
Query: 95 VEKEPCTNGT-RNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHN----REDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLE-PNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMH--CKC-INLCVDRESSE-----KCRKWKQQGQCKELSEAMNIIC-PKTCGF 1366
V K+PC T R GVC P T C GDPHY ++DG+ F G C Y L F + +N+ RG N +Y + V + + + G ++VNG L+ +P +D + ++V++D + V + Y + G+CG+ + ++ + ++ + G S+ C S + C +D + + CG L PF+ C +V +FF+ CV+D+C+ + + C+ + C AG WR+Q C + C +N+H+ PCP +C + T + P EGC C+ G++ CV P++ C C N SE C +W C+ +++C P +CG
Sbjct: 2841 VNKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT-------------CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGPGFCGPLAPGTGGPFTTC--HAHVPPESFFKGCVLDVCMGGGD----RDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV-PLNNGCGCWANGTYHEAGSEFWADGTCSQW-----CRCGPGGGSLVCTPASCGL 3251 HSP 12 Score: 73.559 bits (179), Expect = 5.878e-11 Identity = 101/441 (22.90%), Postives = 170/441 (38.55%), Query Frame = 2
Query: 95 VEKEPCTNGT-RNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHN----REDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLE-PNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMH--CKC-INLCVDRESSE-----KCRKWKQQGQCKELSEAMNIIC-PKTCGF 1366
V K+PC T R GVC P T C GDPHY ++DG+ F G C Y L F + +N+ RG N +Y + V + + + G ++VNG L+ +P +D + ++V++D + V + Y + G+CG+ + ++ + ++ + G S+ C S + C +D + + CG L PF+ C +V +FF+ CV+D+C+ + + C+ + C AG WR+Q C + C +N+H+ PCP +C + T + P EGC C+ G++ CV P++ C C N SE C +W C+ +++C P +CG
Sbjct: 4042 VTKDPCHGVTCRPQETCKEQGGQGVCLPNYEAT-------------CWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRG-NPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPS---IPIWGGSWRAPGWDPLCWDECRGSCPT-CPEDRLEQYEGPGFCGPLSSGTGGPFTTC--HAHVPPESFFKGCVLDVCMGGGD----RDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCV-PLNNGCGCWANGTYHEAGSEFWADGTCSQW-----CRCGPGGGSLVCTPASCGL 4452
BLAST of VWFD domain-containing protein vs. TrEMBL
Match: A0A1C9ZZN4 (Uncharacterized protein (Fragment) OS=Dugesia japonica OX=6161 PE=2 SV=1) HSP 1 Score: 602.823 bits (1553), Expect = 9.337e-175 Identity = 534/1768 (30.20%), Postives = 870/1768 (49.21%), Query Frame = 2
Query: 4628 NNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKC----------KKHHWVLTIKSFHQRPTNIKLFPEIKSRIKATFCEISKKRWVKHVICKPPYKTKVCYPKHN--RLVIKTYFYVVXXXXXXXXXXXXXXXXXXXXXXXXXRSACGPRGDKGRRYLNVTIKRYRQTRQNKCKLIINRRIEVCECEKTKK-MKLCKSGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCR-NNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSXXXXXXXXXXXXXXXTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPXXXXXXXXXX-XXXXXXXXISTGLCTYVIRKYSVFIRKCKCYR-KLIKVIKKERCCKKPKVSY-RCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFK--WIKTGNC----GQHKKXXXXXXXXXLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKK--GTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIG---LCYRDRNG----FAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPC-VPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRKRCV-SNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLG---KCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXX--XXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTK---KCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSK-EVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVL 9802
NN Y+SC +++ Y NC+CV + +C RC +NR++++ T+++ N C + I C R ++ T T YK+ Y+ + NCKC++ K C P F +KC + V T + TN KL PE S IK C +++ ++ + C Y+ C + ++ Y V C + + K I S+CGP G Y+ T + + + ++ CK I + + C +++ + C +G++IF TI +A++ C+ + SI C+N GR NKWI+ R C PGE+TIKY R +N +TC C+R++ S +SICC+P ++ CR NN I I + LKC +IC KP ++G+C + IRYR VSY+ V CRCV+ V+ T SD KC+ SW+ +HI YK CV + +IT + CS + + D+RI+EC F RS+ K+ +C+C D + +IL+Y+CCQK ++ K C ++ T+V I+++LL+FKC+PV++ + + L R++I+T CTY + Y ++CKCYR + + CC + Y RCD + G I V YQ K CI + INC C +CI+NT+TV M+C R+ C+C + + CCG W K G C + + YY R Y L++D +CR+V++++ + C C KSF + +C +N Y K R Y + + C + +V I++C + I + + + GW +I P +C C E+ + C C + R YCK ++ IV + C + WTI I +IV C V++ G C R R F +RYDT VQ++ C C+ K+IK+ C +H+ +QC+ ++I + +YSYSI G C++ V K++ +PCP P + KS+C++N Y +T Y NCRC + R+TCDC+C K+ K KCSRNY + E++ Y+K+ CRC + +++Q PSCPRFI T G C + YR++ R++ ++++NCKC+V +C CRK I K CV +N+ V++ W ++NRR+N+CE+ + +S CP+ I +C + K+I T Y + CKC++ ++ C C VL + G C + RI+ Y ++ C+ ++ VIC C + + C + +V + F L + C + I T ++CS ++T +S C ++GF+ Y+ + + NC+C++R + + C+C+C + + C+ + I T+ C C + I+CPS VS C +R YW +TT T Y + CVCV V IC+ + ++ V C ++ I +LRNG+CV++ N +RI CN W + + SGC+ G + Y +L C+C S+ +C C C+ P + ++R Y ++ RQLIR E C+ +G C N CV+ V ++ +NCRC RR+++ C + C Q++TK C+ + + + C + G I ++ +V K + C TC C + T+ C C C +K EV + C C ++K G C+ + + + + LV+L
Sbjct: 52 NNCYYQSCYKSFYRYQNCRCVRHIESANKCVRCVKP-KREIRCRHNREIVKITNYFIKDNRCHPVHYERVKTIECPRWKVIKTRKHGYTQYKIIYYKVENCKCIQ--------KTCQGPYFRRKCPFSKSTMKCINNNQLVFTQINREIHSTNDKLCPESGSPIKNQICIENRRTRIEPIRCPNNYEKITCIVSRDIRKVKKYYYKVVNCKCVKAVTIEKSRPCKPCDKPIIIHESSCGPFDADGIGYIETTTRYWTRNKKYICKPHIRKSKRIGCCWNSRQTVNECVNGKKIFKTIVREVASQ--CRRRISMIYESIPCYNNGRPNKWIIERIHHCSRPGEFTIKYLVRMQFNPRTCGCRRVRNSVHMSICCRPCRYRTVCRHNNKIVTISNCQRSEKLKCRNYKRETSKILICPKPVKRMIGDCKRRDIRYRIVSYKPVHCRCVQVVKEYTQNPISDVTKCIVD-SWQTTHIGYKFYRNRCVPERPKITIIPVLCSTVETYFDERINECNFTRSYFRKFVSNCRCVDRFVRKEILHYKCCQKPIITKHCVNHNTRVVVSINFKLLNFKCYPVRRELRFPVDCSHLISRKQINTNQCTYNEKYYYGVSKQCKCYRVPKFTIFNLKYCCLPIPLPYTRCDDRRGVLITVQRRYQLVKHK-CIPRISTIEKPINCDGRICETRYGKCIRNTQTVEMFCLKREGCQCAKQIITRHNVCCGPNKDSIWTKIGECKDILNEKEGYYELIRTYALRLDYRTNQCRSVVIRQHYRICDCYKSFARTSCSMNIYIKTRRVSYKMDRPNNVCHKTIDESMVPITTCYKTFTIVMDERETTPDGWCIRTSKITTPVNCGCKERTEKTRFKCPCYKRVDVVRRR-YCKNNDIIVEETLTPRCRLNNIYWTIDRIFTRIVKCSHVQVSHGPTFPCSRYRGDISTRFCTRMRYDTYVQWYVDNCNCRNKLIKQRPWCTECWPSHQHEQCLGSNINVISYSYSIVNGICRRNVDKNLVHIPCPRGPKVHKSRCKKNIYTITTTYYYYANCRCKSRVERRTCDCQCGKDSKEIKCSRNYFLNEITTKYYKRDCRCFKTVNVKQIEPSCPRFIYFTYGKCNIQNYYSIYRKLTTRRIDRNYRNCKCVVVGKSENEVCGCRKEIRKHHDCVNNNYFVIQTWERRINRRKNKCEQVITHVDSKLISCPRMRIEKVCKLNMTIGKEITTKYHLVNCKCIENKSFRRVVCPCYTKPVLEDRGVCNNKTR-RRIEVYWHKEPRGKHCVTVIENKPVICKCKRNKSMTFCNYYQIVHIRTYFNLIISIINYCQRRNIVTYNPVRCSQEITKTQSTCYRSGFQFIYYYAQTVHNCRCIRRRIRVEFCRCKCPSSRIFRKCHPSGNALINIYFTYKHIGCSCKGEIRKHFQPIQCPSRTVIVSGCNEVRCRGYWFRTTTVTNYHPRH-CVCVRNVETIKSICKIQTIKQVSVTCDRRRRLEIRKESELILRNGKCVKLTNENRKRIACNNNWVIINRSGCR---LDGTQISVYQRLHFRNCQCYPESRFTKCKCRCNS-PFVVRKCEGNVNRLYYYRYELRRCECNRQLIRVE-TKRSYCKSKLLNVGPCFEKNNHCVRNVEYQQSVLVNCRCIKRRRIIQRICHS--CCQHSTKIKNYCEKCDTKLITEVTSCWVNYYGRIIRTTQVTSKGVACDEGTTCVSQNDCDYLTSTETLKCTTKTLEKCLCVTKTEVIKKDLCMCGLPKLKFGACDLNSRKRAVYQIENKLVIL 1796
BLAST of VWFD domain-containing protein vs. TrEMBL
Match: A0A1I8HAX6 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 364.385 bits (934), Expect = 2.652e-105 Identity = 191/486 (39.30%), Postives = 280/486 (57.61%), Query Frame = 2
Query: 80 CQNTKVEKEPCTNGTRNIRITTYVKDN-GVCTPFRTKTQVNCES-KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKY---SLIGNSYHV----SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN-----LCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFC--KATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCN 1486
C K ++PC G + + YVKD G C + T V+ E R+ C+C A+GDPH+ YDG +HF G+C+YTLT+ DPC+F+++V+NE+RGDNK +TY + + + +F V+ L Q L V+G++ +PY R+F S ++QFVA +C AFDG +VEV K+Y+ +M G+CG+CNG +DD+ T+ G +V K++ + +L+GNS+ V KPG CK +S S C WI +A+ C L + PF KC G V DC D CVN+ +P+ ++ CE LAE C+EAGF G++WR++ CP++C K+ ++ K PCP++CEN FFGTK CY+LP+REGCAC +G + DG CV+P C+C+ +C D S++KCR+W+ G C M +C +TCG C K C + +S R+C + KG C F C TC
Sbjct: 129 CPKPKTIEKPCVAGKQKVVTIYYVKDRMGNC---KKMTDVDTEVCARRKTCRCDALGDPHFLMYDGVPLHFQGECKYTLTKLRNPADPCAFDVQVKNEHRGDNKNYTYVRLLDVKIFGRVFRLHQHKRLLVDGKIVSLPYT-GPGFRVFYSGPYVQFVATKCRFSAAFDGRYTGYVEVGKQYAGRMVGLCGNCNGKQKDDYVTREGVNVIAKKDNFERDNLVGNSFRVPDDSDKPGKRCKNTPALSASSACSNAWI--PRARALCRRLSDRRGPFGKCIASGRVPSLALANDCRNDACVNRLKPAALRRAVCEAHKDLAEQCAEAGFAGLRWRTKTFCPMKCDKDKVYTTKMQPCPKSCENLFFGTKANCYNLPKREGCACKKGLVLDGRKCVRPEMCQCVKKFPELMCKDDASAKKCRRWRAAGHCASNPYTMLKMCRRTCGLCHTKKAKASCRNIMSVRRCKILKQKGQCGTSFVSTACRRTCG 608
BLAST of VWFD domain-containing protein vs. TrEMBL
Match: A0A1I8JEH9 (Uncharacterized protein OS=Macrostomum lignano OX=282301 PE=4 SV=1) HSP 1 Score: 363.614 bits (932), Expect = 4.885e-105 Identity = 191/486 (39.30%), Postives = 280/486 (57.61%), Query Frame = 2
Query: 80 CQNTKVEKEPCTNGTRNIRITTYVKDN-GVCTPFRTKTQVNCES-KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKY---SLIGNSYHV----SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN-----LCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFC--KATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCN 1486
C K ++PC G + + YVKD G C + T V+ E R+ C+C A+GDPH+ YDG +HF G+C+YTLT+ DPC+F+++V+NE+RGDNK +TY + + + +F V+ L Q L V+G++ +PY R+F S ++QFVA +C AFDG +VEV K+Y+ +M G+CG+CNG +DD+ T+ G +V K++ + +L+GNS+ V KPG CK +S S C WI +A+ C L + PF KC G V DC D CVN+ +P+ ++ CE LAE C+EAGF G++WR++ CP++C K+ ++ K PCP++CEN FFGTK CY+LP+REGCAC +G + DG CV+P C+C+ +C D S++KCR+W+ G C M +C +TCG C K C + +S R+C + KG C F C TC
Sbjct: 129 CPKPKTIEKPCVAGKQKVVTIYYVKDRMGNC---KKMTDVDTEVCARRKTCRCDALGDPHFLMYDGVPLHFQGECKYTLTKLRNPADPCAFDVQVKNEHRGDNKNYTYVRLLDVKIFGRVFRLHQHKRLLVDGKIVSLPYT-GPGFRVFYSGPYVQFVATKCRFSAAFDGRYTGYVEVGKQYAGRMVGLCGNCNGKQKDDYVTREGVNVIAKKDNFERDNLVGNSFRVPDDSDKPGKRCKNTPALSASSACSNAWI--PRARALCRRLSDRRGPFGKCIASGRVPSLALANDCRNDACVNRLKPAALRRAVCEAHKDLAEQCAEAGFAGLRWRTKTFCPMKCDKDKVYTTKMQPCPKSCENLFFGTKANCYNLPKREGCACKKGLVLDGRKCVRPEMCQCVKKFPELMCKDDASAKKCRRWRAAGHCASNPYTMLKMCRRTCGLCHTKKAKASCRNIMSVRRCKILKRKGQCGTSFVSTACRRTCG 608
BLAST of VWFD domain-containing protein vs. TrEMBL
Match: A0A267GW13 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022069g1 PE=4 SV=1) HSP 1 Score: 351.288 bits (900), Expect = 8.969e-103 Identity = 180/449 (40.09%), Postives = 264/449 (58.80%), Query Frame = 2
Query: 188 TQVNCES-KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKY---SLIGNSYHV----SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN-----LCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFC--KATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCN 1486
T V+ E R+ C+C A+GDPH+ YDG +HF G+C+YTLT+ DPC+F+++V+NE+RGDNK +TY + + + +F V+ L Q L V+G++ +PY R+F S ++QFVA +C AFDG +VEV K+Y+ +M G+CG+CNG +DD+ T+ G +V K++ + +L+GNS+ V KPG CK +S S C WI +A+ C L + PF KC G V DC D CVN+ +P+ ++ CE LAE C+EAGF G++WR++ CP++C K+ ++ K PCP++CEN FFGTK CY+LP+REGCAC +G + DG CV+P C+C+ +C D S++KCR+W+ G C M +C +TCG C K C + +S R+C + KG C F C TC
Sbjct: 8 TDVDTEVCARRKTCRCDALGDPHFLMYDGVPLHFQGECKYTLTKLRNPADPCAFDVQVKNEHRGDNKNYTYVRLLDVKIFGRVFRLHQHKRLLVDGKIVSLPYT-GPGFRVFYSGPYVQFVATKCRFSAAFDGRYTGYVEVGKQYAGRMVGLCGNCNGKQKDDYVTREGVNVIAKKDNFERDNLVGNSFRVPDDSDKPGKRCKNTPALSASSACSNAWI--PRARALCRRLSDRRGPFGKCIASGRVPSLALANDCRNDACVNRLKPAALRRAVCEAHKDLAEQCAEAGFAGLRWRTKTFCPMKCDKDKVYTTKMQPCPKSCENLFFGTKANCYNLPKREGCACKKGLVLDGRKCVRPEMCQCVKKFPELMCKDDASAKKCRRWRAAGHCASNPYTMLKMCRRTCGLCHTKKAKASCRNIMSVRRCKILKRKGQCGTSFVSTACRRTCG 453
BLAST of VWFD domain-containing protein vs. TrEMBL
Match: A0A267G000 (Uncharacterized protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig022069g2 PE=4 SV=1) HSP 1 Score: 374.015 bits (959), Expect = 2.011e-100 Identity = 191/486 (39.30%), Postives = 279/486 (57.41%), Query Frame = 2
Query: 80 CQNTKVEKEPCTNGTRNIRITTYVKDN-GVCTPFRTKTQVNCES-KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKY---SLIGNSYHV----SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN-----LCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFC--KATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCN 1486
C K ++PC G + + YVKD G C T V+ E R+ C+C A+GDPH+ YDG +HF G+C+YTLT+ DPC+F+++V+NE+RGDNK +TY + + + +F V+ L Q L V+G++ +PY R+F S ++QFVA +C AFDG +VEV K+Y+ +M G+CG+CNG +DD+ T+ G +V K++ + +L+GNS+ V KPG CK +S S C WI +A+ C L + PF KC G V DC D CVN+ +P+ ++ CE LAE C+EAGF G++WR++ CP++C K+ ++ K PCP++CEN FFGTK CY+LP+REGCAC +G + DG CV+P C+C+ +C D S++KCR+W+ G C M +C +TCG C K C + +S R+C + KG C F C TC
Sbjct: 1291 CPKPKTIEKPCVAGKQKVVTIYYVKDRMGNCKKM---TDVDTEVCARRKTCRCDALGDPHFLMYDGVPLHFQGECKYTLTKLRNPADPCAFDVQVKNEHRGDNKNYTYVRLLDVKIFGRVFRLHQHKRLLVDGKIVSLPYT-GPGFRVFYSGPYVQFVATKCRFSAAFDGRYTGYVEVGKQYAGRMVGLCGNCNGKQKDDYVTREGVNVIAKKDNFERDNLVGNSFRVPDDSDKPGKRCKNTPALSASSACSNAWI--PRARALCRRLSDRRGPFGKCIASGRVPSLALANDCRNDACVNRLKPAALRRAVCEAHKDLAEQCAEAGFAGLRWRTKTFCPMKCDKDKVYTTKMQPCPKSCENLFFGTKANCYNLPKREGCACKKGLVLDGRKCVRPEMCQCVKKFPELMCKDDASAKKCRRWRAAGHCASNPYTMLKMCRRTCGLCHTKKAKASCRNIMSVRRCKILKRKGQCGTSFVSTACRRTCG 1770 HSP 2 Score: 80.4925 bits (197), Expect = 1.105e-10 Identity = 315/1379 (22.84%), Postives = 527/1379 (38.22%), Query Frame = 2
Query: 6860 FVRCKCPKSFTKMTCVLNRY-NKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSK--KTGWRYVVYRIIYPKHCKCVEKKHSFKEICICS---VAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRI-CACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLI-------RQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVI--ISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRI----------RKTNYWLKTTRTTRYFV----NNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXXXXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIP----YTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIM----------TCRQVT---------KCHKKSMTQKFLCRVPHK-TNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKV---------------------------KCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKC--DKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRKIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERV-GCKCEEQIHWIFSLLHCKKPTTTRK-CIENNIVSTKIYYVKER 10741
+ +C C K +T C N + K + + K C ++ V + P K + K+ S+ G+R V + + C CV + S +E C C + R+Y + + D R C KR T S+ + C + ++ C + R T V Y+ C+C ++V R ++ CAC N +C+ +V Y +K G+C K R+V CP K + + KC + + IVT R R+NC+C ++R C C + R CS + S Y C+ + + CP + +G C +D R + + + C C + VKR R+ C C K KR++CV H+ +E+ R C+R VS P C + I + + + LI R C+C+KR RVKK C C + YR KRCE VI FT +C K+ T+ +KC + +S CGK G++ KL +C CVK+ + R CRC + + + ++ + T + L R+K+ KCP+E +C + ++T + R + NR C+ + K + C C + +T V C +++ LI VT L+ +C++ + +C SE+ C+ V +TY K C+C+ K +R C C ST CV+ I + +K + + + + +KC+ G K+ R +C K ++ Y NC C RK + C CP+ T+ +R V+ ++ G Q+ + K+I C+S + RQVT KC + LCR P + CRS+ + T + + GK K TR + +LV V KC++ + K++C CP + K V H+ + K +R + +C ++ +C + + C D R +K I+ R +C+C +R V LR+ C KD+ +CI N V + + + +C + KC+ GF+ + + C C + V+ +++RC C V + C+ +K + K TS+KL+ NRC + + ++SC ++ + K ++ + R+ C C+ + C KP T K C+ IYYVK+R
Sbjct: 64 YEKCGCGKDYTTEKCDDNVWIVKAVNHKMDGAKSAC-----KRSVAVRKKPIKCRGKLHRRVSRCQSDGYRVVRQLVEEARDCVCVTRVTSHRERCRCEKSRIEHECRGNRVYKHRYVQHLVDGR---CLLKR------TTSVVRIKCGENTVKSSDCVK-------GWRTKTYVNYYPYNCKCLKRVYNRQVR-CACPKNRTKTRCIRGVLVKLEKKYEMKDGQCIGHTCKITRRVHCPRKFEVKRGKCTKKQRIVTTRETRRRNCKCKSVVKRTKEVCGCPRPVHRRVCSADQVETIYSTKYKLVDGLCLAEEDEKVIPNKCPSKPLYRRGRC---GSDGSR--VDTWVHHSLRKCVCH-QRVKRLRLRCRCPKPT-KRRKCV-KHRSLEIVKVSHLLIRGVCKRS-VSFQRTPVYCLEEETPIYGRCRGARKGRSAGQRLITYVKHQTRNCRCVKRTRVKKIPCAC-------------------HLLNYR---------------------------TKRCENKKKRFVIRDYRFTEGAERCKKTVKTTNVPIKCDENRSEHKSACGKRGYQTVTLTYHKLVSCACVKKH-KKRRVICRCPKTKVELKPDPKLKWNRKCTTVYRLN-----REKNRCDKKTKCPAETKQKKMCRPVMAPLKAGPCNKETGFQTTELTIGRVVLLPPPQNRYACLVKKVKMKRRCTCPKPART-VKC--RRNVLITVTVTQKLKGQKCIKAKKVDKKATKCPKNS--ISETKCRSDNTKVVTKVTYRKR---NCKCERKVKHRRVLCRCPDPIISTRCVRHTIKERSTVSYQLKSERCRRKKQVSKKKIKCK------GGTKVTRTKCDKRCNQKVTKVTRYIRNCEC---RKKTDISSVKCCCPKSVTRVACIDDSRRVVTTTSWRLV-RGACQRKARKREKKIVCLSNLKPIRGPCKRNGYRQVTFVSYRLRKCKCVRVQRKSNELCRCPKSHSESSCRSERLV-TRRTRYRLQSTGRGK-------KVCTRHVRNLVRSPGCPVDKRVKTTKCREDDFKRITTVRRYQKNCKCRKSVKTEKRRCRCPKSSKKVS--CHSDNVIKVLRTTYTLRGNSCLKDEQTKATKVVCYEKEKPDRSPCGDDGYRQVKLISYQAR---DCKCTRRVRV-LRERCSCPKDYRARECINNNVVSTFVTYTLTSKECIRRSKITKEKPKCKSISKKSKGACRSDGFQSVFYEHEKLVNCECQKQVQTRKIRCACPKTRVKRRCVDNKVVTTK--TSFKLSG--NRCHRSRSHHRSRVSCPAKKRVV------KHKCVGNKRIYEYLEHRLRNCACKLVRQRVVKPCRCPKPKTIEKPCVAGKQKVVTIYYVKDR 1317 HSP 3 Score: 73.559 bits (179), Expect = 1.622e-8 Identity = 158/613 (25.77%), Postives = 254/613 (41.44%), Query Frame = 2
Query: 7496 YSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKY-IVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKH---CRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKT-IEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKT--------GVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKG----------LVLVE------EGKCAKRP--VCVRIDKYRYEILVKGKCIKK-------------------LKEVKVICCCAKKQKYKRCEGHNMVTVIIS-FTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSV-SLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCK-RNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCAC 9175
+ ++ GRC+++V+ + + + C K KS C N Y V R+ C C+ RR+ KC + Y + + V V HK C R ++++ C + + C ++D YR + R+LV++ ++C C+ + + C C K+ IE E G +V ++R ++LV + KR +RI C T G K Y CKCLKR+ ++ RC C K LV +E +G+C + R+ R + +GKC KK +K K +C C + + C + T+ + + L G C+ E KC SK + +CG +G ++ + LR C C +R V R +CRC + KR+ C ++ R ++ + V+ L + C R S + + C E + + C RK + T C CV R K C C N +TK + KK +I +FT +C + T I+C+ + R + +S C RG+ V TLTY KLV C C + K +R C C
Sbjct: 5 FQLRGGRCKEKVKVTKKPIVCNKKYRPVKSSCAFNGYRRVILYNQERRGCECVK--RRRITYEKCGCGKDYTTEKCDDNVWIVKAVNHKMDGAKSACKRSVAVRKKPIKCRGKLHRRVSRC---QSDGYRVV--RQLVEEARDCVCVTRVTSHRERCRCEKSRIEH-----------ECRGNRVY--KHRYVQHLVDGRCLLKRTTS-VVRIKCGENTVKSSDCVKGWRTKTYVNYYPYNCKCLKRVYNRQVRCACPKNRTKTRCIRGVLVKLEKKYEMKDGQCIGHTCKITRRVHCPRKFEVKRGKCTKKQRIVTTRETRRRNCKCKSVVKRTKEVCGCPRPVHRRVCSADQVETIYSTKYKLVDGLCLAEEDEKVIPNKCPSKPLYRRGRCGSDGSRVDTWVHHSLRKCVCHQR-VKRLRLRCRCPKPTKRRKC-VKHRSLEIVKVSHLLIRGVCKRSVSFQRTPVYCLEEETPIYGRCRGARKGRSAGQRLITYVKHQTRNCRCVKRTRVKKIPCACHLLNYRTKRCENKKKRFVIRDYRFTEGAE-RCKKTVKTTNVPIKCD-ENRSEHKSACGKRGYQTV-TLTYHKLVS--CACVKKHKKRRVICRC 589 HSP 4 Score: 67.3958 bits (163), Expect = 1.037e-6 Identity = 91/366 (24.86%), Postives = 162/366 (44.26%), Query Frame = 2
Query: 9866 PNPKDVVKCI-HNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNV-SVVSKYRFVFKNGKCHKFVNRINHIIKCRRS-HVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRKIFTSYKLNER---RNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVST--KIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTTTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSC 10939
P+P +C+ H K R TV + KS++ C ++ + C+ + + KCDK RC +++T + R + NC+CRK+ D+ KCCC K +V CI + VV+ + G C + + I C + RG C R G+R + YR KC+C+R + C C + C ++ + R+ T Y+L + C + +RN R C +++ + T + + F++ TT + + CKC + + C K + C +N++ Y ++ S +K+ K KV+ ++ RS D ++ ++ C+C +V R +CSC
Sbjct: 775 PDPIISTRCVRHTIKERSTVSYQL-KSER-CRRKKQVSKKKIKCKGGTKVTRTKCDK-RCNQKVTKVTRYIRNCECRKKTDISSVKCCCP-KSVTRVACIDDSRRVVTTTSWRLVRGACQRKARKREKKIVCLSNLKPIRGPCK-RNGYRQVTFVSYRLRKCKCVRVQRKSNELCRCPKSHSESSCRSERLVTRR--TRYRLQSTGRGKKVCTRHVRNLVRSPGCPVDKRVK----TTKCREDDFKRITTVRRYQKNCKCRKSVKTEKRRCRCPKSSKKVSCHSDNVIKVLRTTYTLRGNSCLKDEQTKAT---KVVCYEKEKPDRSPCGD----DGYRQVKLISYQARDCKCTRRVRVLRERCSC 1122 HSP 5 Score: 64.3142 bits (155), Expect = 9.678e-6 Identity = 135/577 (23.40%), Postives = 241/577 (41.77%), Query Frame = 2
Query: 7358 TKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSI-VIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKY-IVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKS-----IQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRK---LVKDFKNCKCLVKEVKR-------KRICACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKG-----KCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSL-CIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQ 9019
TKV + + C C++K +K C C + C+ +S V+ S+ + RG CQ++ RK +K+ C + + C+RN Y VT +Y + C+C V ++RK+ + CRC + S ++ V R+ +++ G T R ++R + K K KC + KR ++ C CRK+++ KR RC RCPK + ++ C+ V K + TTY +R CLK + K ++ +V E+ K + P D YR L+ KC ++++ ++ C C K + + C +N+V+ +++TL +C++ T KC S + C +GF+ Y EKL NC+C K V + +C C + ++ C K + T +F L +C R +S + CP++ V C+ ++ +L+ + + N C C + K CRC + + + C A K ++ + + R G C ++ + +
Sbjct: 836 TKVTRYIRNCECRKKTDISSVK-CCCPKSVTRVACIDDSRRVVTTTSWRLVRGACQRKARKREKKIVCLSNLKPIRGPCKRNGYRQVTFVSYRLRKCKC-VRVQRKS----------------------------NELCRCPKSHSESSCRSERLVTRRTRYRLQSTGRGKKVCTRHVRNLVRSPGCPVDKRVKTTKCREDDFKRITTVRRYQKNCKCRKSVKTEKR--------------------RC------------RCPKSSKKVSCH-SDNVIKVLRTTYTLRGNSCLKDEQTKATK------VVCYEKEKPDRSPC--GDDGYRQVKLISYQARDCKCTRRVRVLRERCSCPKDYRARECINNNVVSTFVTYTLTSKECIRRSKITKEKPKCKSISKKSKGACRSDGFQSVFYEHEKLVNCECQK-QVQTRKIRCACPKTRVKRRCVDNK--VVTTKTSFKLSGNRCHRSRSHHRSRVSCPAKKRVVKHKCVGNKRIYEYLE------HRLRN-CACKLVRQRVVKPCRCPKPKTIEKPCVAGKQKVVTIY-YVKDRMGNCKKMTDVDTE 1330
BLAST of VWFD domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000053976.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02001842.1:579:10825:-1 gene:ENSAMXG00000043233.1 transcript:ENSAMXT00000053976.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 151.369 bits (381), Expect = 1.652e-35 Identity = 98/347 (28.24%), Postives = 165/347 (47.55%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNK---RNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+ GDPHY T+D Q+ HF G C Y L++ + P + IE +NE+RG + ++T+ V + ++ E EL + KVNG + P+ ++ +++++S F ++ + V +D S + V Y G+CG+ N DDF+T SG +S+ N ++ G++ PG C+ + C + +CG+L +P PFS C + + + F ++C+ D+CV +Q + C+ + + C + G + WR Q C + C +N+HF CP TC N P LP +E C C+ GY+ CV +C C
Sbjct: 123 CTISGDPHYYTFDNQIFHFQGTCTYVLSEACGDGLP-YYRIEGKNEHRGSTR-VSWTRLVRVFVYDEELELVKDHQYEAKVNGSFASTPFSLRNGSIQVYQS-GFSVAISTDFGLVVTYDAYSYVTISVPFDYQNATCGLCGNFNHHPEDDFRTPSGEVLSSDTDFANSWTATGDT----DPG--CQNTCSGLTCAACTEAQRSLYSNPDYCGILGDPAGPFSSCHSR--LSPQTFMENCIYDLCVGGG----YQPILCQALNVYSAQCQQQGVQLGLWRRQGFCEISCPRNSHFESSGTSCPATCSNPTAPVNCP---LPNQESCICDAGYVLSAGECVSQANCGC 451 HSP 2 Score: 122.094 bits (305), Expect = 1.026e-26 Identity = 94/349 (26.93%), Postives = 142/349 (40.69%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNE-YRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIR---SLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
CSA GDPHY ++DG+ F G CRY L+ + +D P F + +NE + G T SV + + ++G+ ++ + +P S F+ + V++DG V V YS G+CG+ NG DDF+ +SG VS+ S+ G K D S CG R + A+ C +L + P S C VD +F DC D+C+++ + V C C A + WR C + C N+H+ C TC + + C EGC CN G++R G C+ C C+
Sbjct: 896 CSASGDPHYTSFDGRNFDFQGTCRYILSTVCSDNQDLP-FFQVVAKNEAWNGLPVSITVEVSVNVSGHLVLVSRNKRGIAVIDSETKNLPVLLDSGSVSVYSSGQNTFITTDFGLSVSYDGSWVVRVTVPANYSGATCGLCGNFNGQTNDDFRIRSGELVSS-------------ASQFGADWKVGNDTSCDDECGDSCARCQNPVSARSQCEILRDRQGPVSFC--HSYVDPEAYFNDCAFDLCLSEYQ----HDVLCRSIQTYVSACQSANAPVLPWRQNTTCRMDCPMNSHYELCGTDCEHTCASSIDSVCEHAC-----SEGCFCNEGFVRSGGFCIPVEQCGCL 1219 HSP 3 Score: 112.464 bits (280), Expect = 8.679e-24 Identity = 94/405 (23.21%), Postives = 166/405 (40.99%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE------REGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSAR 1411
+ C G Y TYDG + + G C TL++ +F + +Q + G F+ + + ++ + G V+GQ +P+ S + I+ S + V V D + Y+ + G+CG+ N + D+F + G +++ R G+S+ HC+++ DI + S + + HC +L P+ PF++C ++D +DC+ + + ++ CE G A +C + G +WR+ +C C N+H+ CP C P P +EGC C+ G + G CV P+ C C++ R+ E R W + QC+ L IC T GF + C ++ + R
Sbjct: 508 YSTCWVEGPGFYHTYDGLMFSYPGACELTLSRVMGLSPLPNFAVTIQKQPSGPQG-FSRVLTFEAEGTQVSMKMEEGGTATVDGQEVALPFSVGSGRIHIYHSSVKGIIMETTFGVTVRADWPHLIRITAPSTYNGTLGGLCGNFNEYLEDEFLSPDGVLLNDSRT----FGDSWRDGSLSAHCEESTDIWQKGY----YQDSNQFRMHCSILSSPSGPFAQC--HSSLDPSAKVEDCISSL----QQTEGAKEALCEALRGYAVLCQQNGIVLQEWRNITDCEFPCPTNSHYELCGTSCPAAC---------PSLSFPYLCTQHCQEGCQCDDGLLLSGDHCVPPIGCGCLHEGRYRQGGE--RFWHGE-QCQSL-----CICDGTTGFVRCNPSSCSEQETCR 880 HSP 4 Score: 81.6481 bits (200), Expect = 2.154e-14 Identity = 85/345 (24.64%), Postives = 140/345 (40.58%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQF--------VAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCP-------LQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYI 1207
C GDPHY T+DG V F G C Y +++ N D+ F + N +R +NK ++ V I + + GQ+ + + GQ RV + +D D F+ + +F V + V FDG V + + + + G+CG+ NG D K ++ +++ GNS+ C A D Y D + + + C ++ + PF C +V+ +F+ CV D+CV + + C C+ G E +WRS C L+C + EK N C + K+ YD +E C + G +
Sbjct: 1276 SCMVWGDPHYLTFDGAVTTFQGTCSYEISKTCGNLLDNGLEFLVVATNMHR-ENKDVSFASVVDIWLSKG----GQRSQITI-GQNKRVKVDGTDIDSSAFEIGQLAEFHQENDFVVVNASSELMVYFDGRFTLLVRLDESFHGSVCGMCGNNNGDAADDKAMPSGALAPSDDEF---GNSWRSEISTQGC-GAIDQRYDV---NDCPFTQEYSEVCSIITNTSGPFQHC--HFHVNPMVYFRSCVYDLCVYTSA----NGMLCSALEAYEVACTTMGLEISEWRSDLGCSYTDPCAELECTADEWCGEKDNIYGCFCNENHPRPKKESYD--SKEECESSSGTM 1599
BLAST of VWFD domain-containing protein vs. Ensembl Cavefish
Match: zanl (zonadhesin, like [Source:ZFIN;Acc:ZDB-GENE-060131-2]) HSP 1 Score: 147.517 bits (371), Expect = 1.973e-34 Identity = 104/344 (30.23%), Postives = 159/344 (46.22%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK-AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
CS GDPHY ++D +V HF G C YTLT+ N D F +E +NE+R +N +Y KSVI+++F L + ++VNG VP +DV+IF S KF+ + +R FDG+ A + + Y + G+CG+ N D S ++ N+ +G S+ V C DI C K+ + CG++ + F +C + + D +F+ CV D C C+ A +C++AG I WR+ CPL+C +H+ C +C++ G C + P EGC C+ G I G CV C C +
Sbjct: 319 CSVCGDPHYTSFDNKVHHFMGACSYTLTKPCNDTDGLPYFTVETENEHRSNNNKVSYVKSVIVNVFGMKIILDKGRKVQVNGVQVTVPVTLLNDVKIFLSGKFV-VLETNFGLRARFDGNHYADISLPSPYKGLLCGMCGNFNDNPADDNIMSNGKPTDSTNE---LGESWQVPDDRPDCSHGGGDIE----CDKNIENEAQKPTSCGMITDITGIFKECHKFVSPD--PYFESCVFDQCGTDGS----AVALCQAIESYATLCAQAGVP-INWRNNTFCPLKCPAGSHYEHCGTACSPSCQDP--GAAGTCTE-PCVEGCVCDTGLILSGDKCVPFSECGCTD 644 HSP 2 Score: 131.724 bits (330), Expect = 1.384e-29 Identity = 92/369 (24.93%), Postives = 152/369 (41.19%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS------------------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
+ + F KC+ GDPHYRT+D H+ G Y L + HN + F + +N +G N +Y V + ++ + Q VL V+G+ P +RI + ++LQ V+ + V FDG+ + + Y + G+CG+ +G ++ K ++ ++ G+S+ V+ + D+ + C + L + CG L P+ PF+ C D + +DCV D+C ++ +RCE ++ A C E G WR Q C L C N+ ++ CP +C + C EGC C G+ LCV C C L
Sbjct: 1084 RPESFGKCAISGDPHYRTFDTFNHHYQGAYTYILARDHNLPSNLTPFKVRGKNARKGGNNRISYLHEVYVDVYDINVRILQAKVLLVDGERVFPPLSPKQGIRIAMNSRYLQ-VSTDFGLTVRFDGNMQGEILLPSPYKSFVGGLCGNFDGRTNNEYMKPDGTIARLLGEF---GDSWRVTDRQAEGLQVSDLPKLTRLHRREVEEDLDSGFETEGCSAAQLAELNGENQCGALSNPDGPFAACHSVIQPD--TYKEDCVFDLCAEQDS----STLRCENYAVYALACQEQGIVLGPWRQQLGCALTCSANSSYTTCMTTCPASCAD--LAAPSECEQTTCVEGCQCAPGFAMSDTLCVPFSQCGCTYL 1440 HSP 3 Score: 116.316 bits (290), Expect = 6.549e-25 Identity = 98/350 (28.00%), Postives = 155/350 (44.29%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPER---EGCACNRGYIRDGALCVKPMHCKCI 1252
C GDPHY T+DG + + G C YTL E F I +NE RG + +Y +SV +++ V L + + ++GQ R P + + + ++F S ++ + V FDG + + V Y K+ G+CG+ NG DD +G + +G+S+ S PG C+ H C + ++ A+ +L ++ F C + F +C+ DMC + Q C+ A+ C AG I WR+ CPL C N+H+S+ PCP TC + F P + LP EGC C+ G++ CV +C C+
Sbjct: 704 CHIAGDPHYYTFDGVMHTYMGTCTYTLVAICDESMVTPFTIVAKNEERGLPEA-SYVRSVTVYLPGAVITLSKSKRVLLDGQRIRTPMDILAANAQVFTS-GVNTVLSTDFGLIVQFDGVHHVEITVPGDYFNKVCGMCGNYNGNSSDDNLMPNGNPAKDDIE----LGDSWKAEGDSDPG--CQPDLRPDVHPNCTAEEEEAIAAQCSSIIL---SDRFKPCHSL--IPPEPFLGNCIYDMC----EYNGMQSTLCDNVEAYAQACQSAGVT-ISWRNTTFCPLPCPPNSHYSDCTPPCPPTCADLF-----PIFCPLPPNGCVEGCQCDSGFVLSDGKCVPLSNCGCV 1030 HSP 4 Score: 92.8189 bits (229), Expect = 7.053e-18 Identity = 80/293 (27.30%), Postives = 122/293 (41.64%), Query Frame = 2
Query: 455 VLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAK----KHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER--EGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKC--RKWKQQG 1309
+ VNG +P+ S + I + +++ P + V +DG+ A + V Y ++M G+CGD NG ++ TK ++ N + G+S+ + D S++A+ CG + + + PF C + VD FFQ CV DMC R + C+ + C AG +WR CPL C N+H+S + CP TC G P E+ EGC C+ G++ CV C CVD E S KW +G
Sbjct: 6 TILVNGLRVGLPHSPSPLISITLAGQYVILTTPF-GLEVRWDGNHYAKITVPSTYYEQMCGLCGDYNGNPNNDFTKPNGSLAGNINDF---GSSWQTDE------DEDDTCKPVPPEPPCDPSIEAEVVKPDKCGKITDTSGPFRDCIKV--VDPTPFFQSCVFDMC----RYQGLIQTLCDQLQAYTDACLGAGAPVHQWREPDFCPLVCPPNSHYSTCVSSCPETC----LGVSGP-LGCGEKCVEGCECDPGFVLSNNKCVPLKDCG----CVDPEGSYHPINDKWYLEG 273
BLAST of VWFD domain-containing protein vs. Ensembl Cavefish
Match: zanl (zonadhesin, like [Source:ZFIN;Acc:ZDB-GENE-060131-2]) HSP 1 Score: 147.517 bits (371), Expect = 2.050e-34 Identity = 104/344 (30.23%), Postives = 159/344 (46.22%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK-AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
CS GDPHY ++D +V HF G C YTLT+ N D F +E +NE+R +N +Y KSVI+++F L + ++VNG VP +DV+IF S KF+ + +R FDG+ A + + Y + G+CG+ N D S ++ N+ +G S+ V C DI C K+ + CG++ + F +C + + D +F+ CV D C C+ A +C++AG I WR+ CPL+C +H+ C +C++ G C + P EGC C+ G I G CV C C +
Sbjct: 369 CSVCGDPHYTSFDNKVHHFMGACSYTLTKPCNDTDGLPYFTVETENEHRSNNNKVSYVKSVIVNVFGMKIILDKGRKVQVNGVQVTVPVTLLNDVKIFLSGKFV-VLETNFGLRARFDGNHYADISLPSPYKGLLCGMCGNFNDNPADDNIMSNGKPTDSTNE---LGESWQVPDDRPDCSHGGGDIE----CDKNIENEAQKPTSCGMITDITGIFKECHKFVSPD--PYFESCVFDQCGTDGS----AVALCQAIESYATLCAQAGVP-INWRNNTFCPLKCPAGSHYEHCGTACSPSCQDP--GAAGTCTE-PCVEGCVCDTGLILSGDKCVPFSECGCTD 694 HSP 2 Score: 131.724 bits (330), Expect = 1.132e-29 Identity = 92/369 (24.93%), Postives = 152/369 (41.19%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS------------------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
+ + F KC+ GDPHYRT+D H+ G Y L + HN + F + +N +G N +Y V + ++ + Q VL V+G+ P +RI + ++LQ V+ + V FDG+ + + Y + G+CG+ +G ++ K ++ ++ G+S+ V+ + D+ + C + L + CG L P+ PF+ C D + +DCV D+C ++ +RCE ++ A C E G WR Q C L C N+ ++ CP +C + C EGC C G+ LCV C C L
Sbjct: 1134 RPESFGKCAISGDPHYRTFDTFNHHYQGAYTYILARDHNLPSNLTPFKVRGKNARKGGNNRISYLHEVYVDVYDINVRILQAKVLLVDGERVFPPLSPKQGIRIAMNSRYLQ-VSTDFGLTVRFDGNMQGEILLPSPYKSFVGGLCGNFDGRTNNEYMKPDGTIARLLGEF---GDSWRVTDRQAEGLQVSDLPKLTRLHRREVEEDLDSGFETEGCSAAQLAELNGENQCGALSNPDGPFAACHSVIQPD--TYKEDCVFDLCAEQDS----STLRCENYAVYALACQEQGIVLGPWRQQLGCALTCSANSSYTTCMTTCPASCAD--LAAPSECEQTTCVEGCQCAPGFAMSDTLCVPFSQCGCTYL 1490 HSP 3 Score: 116.316 bits (290), Expect = 5.905e-25 Identity = 98/350 (28.00%), Postives = 154/350 (44.00%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPER---EGCACNRGYIRDGALCVKPMHCKCI 1252
C GDPHY T+DG + + G C YTL E F I +NE RG + +Y +SV +++ V L + + ++GQ R P + + + ++F S ++ + V FDG + + V Y K+ G+CG+ NG DD +G + +G+S+ S PG C+ H C + ++ A+ +L ++ F C + F +C+ DMC Q C+ A+ C AG I WR+ CPL C N+H+S+ PCP TC + F P + LP EGC C+ G++ CV +C C+
Sbjct: 754 CHIAGDPHYYTFDGVMHTYMGTCTYTLVAICDESMVTPFTIVAKNEERGLPEA-SYVRSVTVYLPGAVITLSKSKRVLLDGQRIRTPMDILAANAQVFTS-GVNTVLSTDFGLIVQFDGVHHVEITVPGDYFNKVCGMCGNYNGNSSDDNLMPNGNPAKDDIE----LGDSWKAEGDSDPG--CQPDLRPDVHPNCTAEEEEAIAAQCSSIIL---SDRFKPCHSL--IPPEPFLGNCIYDMCEYNGM----QSTLCDNVEAYAQACQSAGVT-ISWRNTTFCPLPCPPNSHYSDCTPPCPPTCADLF-----PIFCPLPPNGCVEGCQCDSGFVLSDGKCVPLSNCGCV 1080 HSP 4 Score: 106.301 bits (264), Expect = 7.208e-22 Identity = 93/348 (26.72%), Postives = 147/348 (42.24%), Query Frame = 2
Query: 290 GDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAK----KHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER--EGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKC--RKWKQQG 1309
G C YTL + R + F++E +NE RG +Y + + + + + + + VNG +P+ S + I + +++ P + V +DG+ A + V Y ++M G+CGD NG ++ TK ++ N + G+S+ + D S++A+ CG + + + PF C + VD FFQ CV DMC R + C+ + C AG +WR CPL C N+H+S + CP TC G P E+ EGC C+ G++ CV C CVD E S KW +G
Sbjct: 2 GTCTYTLARPCRNNTGPWFSVEGKNEERG-LAGVSYLRKLYVTVDNITVTMMKSRTILVNGLRVGLPHSPSPLISITLAGQYVILTTPF-GLEVRWDGNHYAKITVPSTYYEQMCGLCGDYNGNPNNDFTKPNGSLAGNINDF---GSSWQTDE------DEDDTCKPVPPEPPCDPSIEAEVVKPDKCGKITDTSGPFRDCIKV--VDPTPFFQSCVFDMC----RYQGLIQTLCDQLQAYTDACLGAGAPVHQWREPDFCPLVCPPNSHYSTCVSSCPETC----LGVSGP-LGCGEKCVEGCECDPGFVLSNNKCVPLKDCG----CVDPEGSYHPINDKWYLEG 323
BLAST of VWFD domain-containing protein vs. Ensembl Cavefish
Match: zanl (zonadhesin, like [Source:ZFIN;Acc:ZDB-GENE-060131-2]) HSP 1 Score: 147.517 bits (371), Expect = 2.050e-34 Identity = 104/344 (30.23%), Postives = 159/344 (46.22%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKK-AKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
CS GDPHY ++D +V HF G C YTLT+ N D F +E +NE+R +N +Y KSVI+++F L + ++VNG VP +DV+IF S KF+ + +R FDG+ A + + Y + G+CG+ N D S ++ N+ +G S+ V C DI C K+ + CG++ + F +C + + D +F+ CV D C C+ A +C++AG I WR+ CPL+C +H+ C +C++ G C + P EGC C+ G I G CV C C +
Sbjct: 369 CSVCGDPHYTSFDNKVHHFMGACSYTLTKPCNDTDGLPYFTVETENEHRSNNNKVSYVKSVIVNVFGMKIILDKGRKVQVNGVQVTVPVTLLNDVKIFLSGKFV-VLETNFGLRARFDGNHYADISLPSPYKGLLCGMCGNFNDNPADDNIMSNGKPTDSTNE---LGESWQVPDDRPDCSHGGGDIE----CDKNIENEAQKPTSCGMITDITGIFKECHKFVSPD--PYFESCVFDQCGTDGS----AVALCQAIESYATLCAQAGVP-INWRNNTFCPLKCPAGSHYEHCGTACSPSCQDP--GAAGTCTE-PCVEGCVCDTGLILSGDKCVPFSECGCTD 694 HSP 2 Score: 131.724 bits (330), Expect = 1.132e-29 Identity = 92/369 (24.93%), Postives = 152/369 (41.19%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHS------------------ICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
+ + F KC+ GDPHYRT+D H+ G Y L + HN + F + +N +G N +Y V + ++ + Q VL V+G+ P +RI + ++LQ V+ + V FDG+ + + Y + G+CG+ +G ++ K ++ ++ G+S+ V+ + D+ + C + L + CG L P+ PF+ C D + +DCV D+C ++ +RCE ++ A C E G WR Q C L C N+ ++ CP +C + C EGC C G+ LCV C C L
Sbjct: 1134 RPESFGKCAISGDPHYRTFDTFNHHYQGAYTYILARDHNLPSNLTPFKVRGKNARKGGNNRISYLHEVYVDVYDINVRILQAKVLLVDGERVFPPLSPKQGIRIAMNSRYLQ-VSTDFGLTVRFDGNMQGEILLPSPYKSFVGGLCGNFDGRTNNEYMKPDGTIARLLGEF---GDSWRVTDRQAEGLQVSDLPKLTRLHRREVEEDLDSGFETEGCSAAQLAELNGENQCGALSNPDGPFAACHSVIQPD--TYKEDCVFDLCAEQDS----STLRCENYAVYALACQEQGIVLGPWRQQLGCALTCSANSSYTTCMTTCPASCAD--LAAPSECEQTTCVEGCQCAPGFAMSDTLCVPFSQCGCTYL 1490 HSP 3 Score: 116.316 bits (290), Expect = 5.905e-25 Identity = 98/350 (28.00%), Postives = 154/350 (44.00%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHV---SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPER---EGCACNRGYIRDGALCVKPMHCKCI 1252
C GDPHY T+DG + + G C YTL E F I +NE RG + +Y +SV +++ V L + + ++GQ R P + + + ++F S ++ + V FDG + + V Y K+ G+CG+ NG DD +G + +G+S+ S PG C+ H C + ++ A+ +L ++ F C + F +C+ DMC Q C+ A+ C AG I WR+ CPL C N+H+S+ PCP TC + F P + LP EGC C+ G++ CV +C C+
Sbjct: 754 CHIAGDPHYYTFDGVMHTYMGTCTYTLVAICDESMVTPFTIVAKNEERGLPEA-SYVRSVTVYLPGAVITLSKSKRVLLDGQRIRTPMDILAANAQVFTS-GVNTVLSTDFGLIVQFDGVHHVEITVPGDYFNKVCGMCGNYNGNSSDDNLMPNGNPAKDDIE----LGDSWKAEGDSDPG--CQPDLRPDVHPNCTAEEEEAIAAQCSSIIL---SDRFKPCHSL--IPPEPFLGNCIYDMCEYNGM----QSTLCDNVEAYAQACQSAGVT-ISWRNTTFCPLPCPPNSHYSDCTPPCPPTCADLF-----PIFCPLPPNGCVEGCQCDSGFVLSDGKCVPLSNCGCV 1080 HSP 4 Score: 106.301 bits (264), Expect = 7.208e-22 Identity = 93/348 (26.72%), Postives = 147/348 (42.24%), Query Frame = 2
Query: 290 GDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAK----KHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER--EGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKC--RKWKQQG 1309
G C YTL + R + F++E +NE RG +Y + + + + + + + VNG +P+ S + I + +++ P + V +DG+ A + V Y ++M G+CGD NG ++ TK ++ N + G+S+ + D S++A+ CG + + + PF C + VD FFQ CV DMC R + C+ + C AG +WR CPL C N+H+S + CP TC G P E+ EGC C+ G++ CV C CVD E S KW +G
Sbjct: 2 GTCTYTLARPCRNNTGPWFSVEGKNEERG-LAGVSYLRKLYVTVDNITVTMMKSRTILVNGLRVGLPHSPSPLISITLAGQYVILTTPF-GLEVRWDGNHYAKITVPSTYYEQMCGLCGDYNGNPNNDFTKPNGSLAGNINDF---GSSWQTDE------DEDDTCKPVPPEPPCDPSIEAEVVKPDKCGKITDTSGPFRDCIKV--VDPTPFFQSCVFDMC----RYQGLIQTLCDQLQAYTDACLGAGAPVHQWREPDFCPLVCPPNSHYSTCVSSCPETC----LGVSGP-LGCGEKCVEGCECDPGFVLSNNKCVPLKDCG----CVDPEGSYHPINDKWYLEG 323
BLAST of VWFD domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000034930.1 (pep primary_assembly:Astyanax_mexicanus-2.0:APWO02000038.1:2656807:2676617:1 gene:ENSAMXG00000010839.2 transcript:ENSAMXT00000034930.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.576 bits (340), Expect = 8.151e-31 Identity = 111/376 (29.52%), Postives = 167/376 (44.41%), Query Frame = 2
Query: 158 NGVCTPFRTKTQVN----CESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKY--FTYTKSVIIHMFREVYELGQKGV-LKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
N C P+ + VN C+ C+ A GDPHY ++DG F G CRY L+Q + F++EV+NE R N Y + +K V + +F + L + + VNG L+ +P+ +D VRI+K + +RV +D V V Y + G+CG+ +G R+D SG N +L G ++ V PG C D + C +A +CG++ +P+ PF+ C +D + Q+CV D+CV+ V C + A C AG KWR+ CPL C + H+ A+ TC T Y EGC C+ GY+ +G CV C C+
Sbjct: 267 NFSCGPYESCVVVNGVRQCQPVGNAVCQ--ASGDPHYLSFDGFRYDFQGGCRYMLSQSCGLQGTSLVPFSVEVENE-RWPNSYVKVSVSKQVSLAVFGYTFVLRRSTAQILVNGLLTNLPWSLNDTKVRIYKEGTNYVMMTDF-GLRVTYDLWYYVTVTVPSSYLNRTCGLCGNYDGNPRNDLVLPSG----NTTTDVNLFGKAWKVLIPGVDCVDF-DSGPDADCNPKLRAIFEAPTYCGLISDPSGPFAAC--HAVIDPSGYLQNCVFDVCVSGGS----STVACHGVAAYASKCQTAGVVIKKWRTDSFCPLSCPQFMHYELCADTAAATCPGL---TDIIQYSSRCAEGCTCDIGYLFNGLSCVPYEDCGCM 624 HSP 2 Score: 108.997 bits (271), Expect = 9.490e-23 Identity = 92/351 (26.21%), Postives = 158/351 (45.01%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFR-----EVYELGQKGVLKVNGQLS----RVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+DG F G C YTL+Q + F++ N+ RG Y +Y + V + ++ + Y+ GQ V K+ L RV ++ + ++ LQ + +D +S+ +++ +Y + + G+CG+ NG + D G +++ + + S+PG C+ D S +C D + + +CGVL ++ F C+ K VD F + CV D+C++ ++ C+ A +C A + WR +FNCP++C N+H+ A TC ++P E C C+ G++ G+ CV C C
Sbjct: 733 TCWARGDPHYFTFDGFYYDFQGTCTYTLSQTCGPLNGLEPFSVTESNDNRGSTSY-SYVREVEVKVYGITITIQKYQWGQVTVQKLYLPLMLLDHRVQVQQVGSYAVVQTDFGLQ---------LKYDWNSDVNLQLPGQYYQHVCGLCGNFNGNQSDELIGPGGVQQATVIQWASSWRT-NASEPG--CRDTCD-SNCPVCSSDQQKLYNSDAYCGVL-STSDLFKPCSSK--VDPAVFQKTCVYDLCLSNGN----HRMLCDALQSYASMCRMADVVLLGWREKFNCPMRCQPNSHYEGCATSFNTTCPTP---QQQPNRTGVCVEACVCDPGFLLSGSTCVPAAQCGC 1059 HSP 3 Score: 100.523 bits (249), Expect = 4.083e-20 Identity = 93/355 (26.20%), Postives = 140/355 (39.44%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVS---------KPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
C A GDPHYRT+DG F G Y L + FN+ VQNE RG + ++T++V + +F V + ++ + V+ L +P E + + I + +RV FD S V + YS + G+CG+ NG +DD G N ++G S+ V P +C A+ +AK+ C ++ +P PF C R V + DCV D C Q V C+ + C I F+ C ++++S C +TC + + R C EGC C GY+ G CV C C
Sbjct: 1112 TCEAFGDPHYRTFDGLAFDFQGTSVYQLVALCSNRTYLVPFNVTVQNENRGRSA-VSFTRAVTVSVFGVVITITREYPRQVLVSMLLMELPLEMQNMLVIHHGGN-AAVLETSFGLRVTFDWISTLRVTLPNSYSGAVCGLCGNFNGSTQDDMAMPGGSLAPNAW----VLGQSWQVGGTPDSSSGPPPTQNCTAAQ--------------MEEAKRLCSIISDPAGPFRACHRV--VAPGPYENDCVFDTCQYPGL----QSVLCDAVAAYLYYCI------IYAVLLFSTAQFCPPHSNYSLCVPGCVQTCASVSWSCSRSC-----AEGCQCEPGYVFSGQACVPLADCGCF 1429 HSP 4 Score: 92.0485 bits (227), Expect = 1.546e-17 Identity = 67/236 (28.39%), Postives = 108/236 (45.76%), Query Frame = 2
Query: 563 VRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSL-----IGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+ VAFD +S V V Y + G+CG+ + +K+G D+ + +S G S+ V+ PG C A S C + + +CG++L+PN PF++C + +D FF++CV D+C R + + C+ S C + G WR+ C +QC ++H+ CP TC + G C P +E C C++G+I G CV C C+
Sbjct: 17 LTVAFDWNSIGSVSVPSTYMAAVCGLCGN-------YNSKTGDDLMLRGTNFSSSSPDNFGESWKVADVPG--CVNACS-GNCSTCEAAHRQIYASADYCGLILDPNGPFTEC--QALLDPSLFFENCVYDVCAYLGR----KDILCQAISAYMSACQDIGARVYPWRTADFCGVQCPPHSHYDVCGPGCPATC--YGLGLPLSC-QRPCKESCVCDQGFILSGDDCVPFSQCGCL 233
BLAST of VWFD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000981.1 (pep scaffold:Pmarinus_7.0:GL476384:615201:646381:-1 gene:ENSPMAG00000000884.1 transcript:ENSPMAT00000000981.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 135.961 bits (341), Expect = 1.178e-31 Identity = 103/387 (26.61%), Postives = 171/387 (44.19%), Query Frame = 2
Query: 110 CTNGTRNIRITTYV-KDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C N N+ +V KD+ +C+ + C ++ C GDPHY T+D HF G+C YT N+ FN+E NE+RG + +Y K V + ++ + L + + V+G P+ S V I S ++ + ++ V FDG+ + + V Y+ ++ GICG+ NG D K + N+ +GNS+ V + C+ + C ++ ++ CG++ +P F +C + + FF +CV D+C C+ A+ C++AG + WR+ CP C +H+ A PCP TC N G + C EGC C+ G++ G CV C C++
Sbjct: 855 CVNPGGNVSCDAWVCKDDEICS--VVDGILGCHTQEPG--DCVITGDPHYITFDKTTHHFMGECTYTAAVPCNQSSTLPHFNVETTNEFRGGSTAVSYVKDVHVDVYGHRFTLAKGRRVLVDGLRVTPPFFMSG-VYIQLSGSYV-VLETDFNLVVRFDGNHHVEIVVPGEYAGQLCGICGNFNGDGSDDNLKPDGSAAASSNE---LGNSWRVFNSSDDDCQDGTE--EIPPCDENDKDVYESDSFCGIITDPEGAFKECHAV--LPPQVFFDNCVFDLCATGGD----HGSLCQALQAYADQCAQAGVI-VTWRNNTFCPFPCEPGSHYESCAPPCPATCSNASLPGGCNQQC-----AEGCVCDDGFVLSGDKCVPVELCGCLD 1218 HSP 2 Score: 130.954 bits (328), Expect = 3.189e-30 Identity = 96/354 (27.12%), Postives = 156/354 (44.07%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS--------FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+D HF G+C YT PC+ FN+E NE+RG + +Y K V + ++ + L + + V+G P+ S V I S ++ + ++ V FDG+ + + V Y+ ++ GICG+ NG D K + ++ +GNS+ V + C+ D C ++ ++ CG++ +P F +C + + FF +CV D+C C+ A+ C++AG + WR+ CP C +H+ A PCP TC N G + C EGC C+ G++ G CV C C++
Sbjct: 503 DCVITGDPHYITFDKTTHHFMGECTYTAAI------PCNQSSTLLPHFNVETTNEFRGGSTAVSYVKEVHVDVYGHRFTLAKGRRVLVDGLRVTPPFFMSG-VYIQLSGSYV-VLETDFNLVVRFDGNHHVEIVVPGEYAGQLCGICGNFNGDGSDDNLKPDGSAAASSSE---LGNSWRVFNSSDDDCQD--DTGEIPPCDENDKNLYESDTFCGIITDPEGAFKECHAV--LPPQVFFDNCVFDLCATGGD----HGSLCQALQAYADQCAQAGVI-VTWRNNTFCPFPCEPGSHYESCAPPCPATCSNASLPGGCNQQC-----AEGCVCDDGFVLSGDKCVPTEQCGCLD 831 HSP 3 Score: 130.183 bits (326), Expect = 5.573e-30 Identity = 95/347 (27.38%), Postives = 155/347 (44.67%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENH--FFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+D HF G+C YT N+ FN+E NE+RG + +Y K V + ++ + L + + V+G P+ S V I S ++ + ++ V FDG+ + + V Y+ ++ GICG+ NG D K + ++ +GNS+ V + C+ D C ++ ++ CG++ +P F +C + + FF +CV D+C C+ A+ C++AG + WR+ CP C +H+ A PCP TC N G + C EGC C+ G++ G CV C C++
Sbjct: 117 DCVITGDPHYITFDKTTHHFMGECTYTAAIPCNQSSTLPHFNVETTNEFRGGSTAVSYVKEVHVDVYGHRFTLAKGRRVLVDGLRVTPPFFMSG-VYIQLSGSYV-VLETDFNLVVRFDGNHHVEIVVPGEYAGQLCGICGNFNGDGSDDNLKPDGSAAASSSE---LGNSWRVFNSSDDDCQD--DTGEIPPCDENDKNLYESDTFCGIINDPEGAFKECHAV--LPPQIFFDNCVFDLCATGGD----HGSLCQALQAYADQCAQAGVI-VTWRNNTFCPFPCEPGSHYESCAPPCPATCSNANPPAGCNQQC-----AEGCVCDDGFVLSGDKCVPTDQCGCLD 444
BLAST of VWFD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000005510.1 (pep scaffold:Pmarinus_7.0:GL476588:620363:669144:-1 gene:ENSPMAG00000004964.1 transcript:ENSPMAT00000005510.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 134.42 bits (337), Expect = 3.720e-31 Identity = 97/374 (25.94%), Postives = 157/374 (41.98%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVR------VAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCK 1318
C GDPHY T+D HF G+C YT N+ FN+E NE+RG + +Y K V + ++ + L + + V+G P +F S ++Q + V FDG+ + + V Y+ ++ GICG+ NG D K + N+ +GNS+ V + C+ C ++ ++ CG++++ F +C + + FF +CV D+C C+ A+ C++AG + WR+ CP C +H+ A PCP TC N G + C EGC C+ G++ G CV C C++ D + W + G C
Sbjct: 504 DCVITGDPHYITFDKTTHHFMGECTYTAAIPCNQSSTLPHFNVETTNEFRGGSTAVSYVKEVHVDVYGHRFTLAKGRRVLVDGLRVTPP--------VFMSGVYIQLSGSYVVLETDFNLVVRFDGNHHVEIVVPGEYAGQLCGICGNFNGDGSDDNLKPDGSAAASSNE---LGNSWRVFNSSDDDCQDGT--GEIPPCDENDKDVYESDSFCGIIIDDEGAFKEC--HAVLPPQVFFDNCVFDLCATDGD----HGSLCQALQAYADQCAQAGVI-VTWRNNTFCPFPCEPGSHYESCAPPCPATCSNASLPGGCNQQC-----AEGCVCDDGFVLSGDKCVPVELCGCLDF--DNQYHPLGESWFESGNCS 850 HSP 2 Score: 133.265 bits (334), Expect = 9.473e-31 Identity = 95/348 (27.30%), Postives = 156/348 (44.83%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYT--LTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENH--FFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+D HF G+C YT + + P FN+E NE+RG + +Y K V + ++ + L + + V+G P+ S V I S ++ + ++ V FDG+ + + V Y+ ++ GICG+ NG D K + ++ +GNS+ V + C+ D C ++ ++ CG++ +P F +C + + FF +CV D+C C+ A+ C++AG + WR+ CP C +H+ A PCP TC N G + C EGC C+ G++ G CV C C++
Sbjct: 117 DCVITGDPHYITFDKTTHHFMGECTYTAAIPCNQSSTLPPHFNVETTNEFRGGSTAVSYVKEVHVDVYGHRFTLAKGRRVLVDGLRVTPPFFMSG-VYIQLSGSYV-VLETDFNLVVRFDGNHHVEIVVPGEYAGQLCGICGNFNGDGSDDNLKPDGSAAASSSE---LGNSWRVFNSSDDDCQD--DTGEIPPCDENDKNLYESDTFCGIITDPEGAFKEC--HAVLPPQIFFDNCVFDLCATGGD----HGSLCQALQAYADQCAQAGVI-VTWRNNTFCPFPCEPGSHYESCAPPCPATCSNANPPAGCNQQC-----AEGCVCDDGFVLSGDKCVPTDQCGCLD 445 HSP 3 Score: 127.872 bits (320), Expect = 3.537e-29 Identity = 99/355 (27.89%), Postives = 156/355 (43.94%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEK-SDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGH----------HCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE-REGCACNRGYIRDGALCVKPMHCKC 1249
C GDPHY T+D HF G+C YT N+ FN+E NE+RG + +Y K V + ++ + L + + V+ + + P E V+I S ++ + V V FDG + + Y K+ G+CG+ N DD+ +G+ ++ + +G+S+ CK + I G D I KK C V++ + F+KC + +D F + C+ DMC + C+ F AE C G I WR++ CPL C N H++ A+PCP TC + + + C EGC C++G++ LCV C C
Sbjct: 890 DCVITGDPHYITFDKTTHHFMGECTYTAAVPCNQSSTLPHFNVETTNEFRGGSTTVSYVKEVHVEVYGYRFTLAKGRRVLVDDKRVKTPIEGLVPGVKIGISGSYV-LLETDFGVTVKFDGKHHLEINTPSTYFNKLCGLCGNYNQNGTDDYLMPNGKLATSA----AQLGDSWKAEGDDDAGSTLWVGEVSCKPDEP----HIPGCDPINEEAYKKMCEVVISTSGAFAKCHAE--IDPEPFLKTCIYDMCQFHGM----ESTLCDNFQAYAEACRAKGIN-ILWRNETFCPLPCPPNTHYTPCASPCPATCSDIY--AEDGCQSAARCAEGCVCDQGFVLSDDLCVSLEACGC 1226 HSP 4 Score: 120.168 bits (300), Expect = 7.471e-27 Identity = 89/343 (25.95%), Postives = 157/343 (45.77%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDI------SYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALC 1225
+ CS GDPHY+T+D ++ HF G YTL Q ++ I +N+ G N ++ +V I+++ + + ++NG ++ P + + I + + + + V FD S+A V + Y+ ++ G+CG+ NG + D+FKT G V+++ + GNS+ V+ +++K + + C + L+ K CGV +P PF +C VD ++ +C+ DMC N +++ C C + G WR C QC + + E+ + CP TC + C +LP+ EGC C G++ G C
Sbjct: 1284 YSTCSISGDPHYQTFDKRLYHFMGRETYTLVQSCGDNNNLLPIRILGKNKRVGHNHRVSFLDAVYIYVYGFKIKFTDRKDFELNGVRTKPPSNPKEGLEIVHTSHKM-VLRTDFGLTVIFDRKSHADVTIPSSYAGQVCGLCGNSNGDKSDEFKTPDGSLVTSE----DVFGNSWEVNDRRSLFEQSKRLVEEPRNDLNLSCSDEQWAELENKSSCGVFHDPAGPFVQCWIPAPVD--PYYTNCMYDMCENIGD----KELFCSSLEVYTSACQQEGITPNNWRIYTGCAQQCAAHNIYVERMSACPSTCGD--LAASSNC-ELPDVEGCQCMPGFVMSGFDC 1612
BLAST of VWFD domain-containing protein vs. Ensembl Sea Lamprey
Match: tecta (tectorin alpha [Source:ZFIN;Acc:ZDB-GENE-110411-120]) HSP 1 Score: 133.65 bits (335), Expect = 7.004e-31 Identity = 101/348 (29.02%), Postives = 165/348 (47.41%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHM--FREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNC--PLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C+ GDPHY T+D V HF G C YTL + R + SF++ ++E+RG + ++TK V + + F + G + + VN +L+ +P+ + +R +S + ++ + V +D D A + V + ++ G+CG+ N RD+F +G ++ + GNS+ V + G C + I C + + + + + CG++ PN PF+ C + NF + CV DMC + V C+ S A C WR Q NC QCG N+H+ + CP +C+ G + C LP EGC C+ G++ G CV P C C
Sbjct: 320 CTVSGDPHYNTFDRVVHHFQGTCAYTLARTCLERPTELSSFHVIAKSEHRGSST-VSWTKLVQLEVYGFSLIINKGDRSRVLVNEELTSLPFTLLNGRIRASQSGSSVA-ISTDFGLTVTYDTDHYATITVPGAFKGRLCGVCGNYNDDERDEFTMPNGTVTTS----VTEFGNSW-VQEAG--CDQV--ILPPPACTEAVLSTYRGESFCGLISNPNGPFAVCGTV--LSAFNFLESCVFDMCATGGD----RDVLCQSLSAFASACQAHRATIQAWRQQVNCLSAKQCGANSHYEVCTSSCPESCDGQ--GRRSRC-GLPCHEGCRCDEGHVLSGGRCVPPSACGC 647 HSP 2 Score: 116.316 bits (290), Expect = 1.413e-25 Identity = 112/396 (28.28%), Postives = 163/396 (41.16%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGV--LKVNGQLSRVPYEKSDDVRIFKSRKFLQ-----FVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLI------GNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAM---NIICPKTCG 1363
C A GDPHY T+DG F G CRYTL + FN+EV+N+ RG + +YT V + ++ +G+ ++V+G L +P V I +Q V +RV +DG A V + + Y G+CG+ NG DDF G ++ +N + G+ P C A+ Y S CG L++P PF +C R V F CV D+C R + C+ S A C AG WR+ CP+ C N+H+ +N C R+C + C P EGC CN G + CV C C + + S E W ++ C+E E +++C T G
Sbjct: 709 CQAAGDPHYYTFDGAAFDFMGTCRYTLAKTCAGGGGAVPFNVEVENDDRG-SLVVSYTNLVKVDVYGHSIVIGRADYPRVRVDGVLVNLP------VTIIPGNLTVQTGSATLVETNFGLRVQYDGHHVATVWLPRDYRGLTCGLCGNYNGNATDDFLLPDG-SLAASQNHFGQAWTVRGDGDCQATEPPSEPCPDAERPQYAS------------GAFCGPLVDPEGPFRECHRI--VRPEPHFGSCVTDVCALGGRIT----ALCDALSAYAAACQAAGVGVSGWRNSTFCPMSCQSNSHYELCSNTCQRSCSD--LAQPTICSRGPCAEGCRCNPGTVWRSGRCVPLAECGCFHGGRNYASGEAF--WPEE-LCRERCECRRDGSVVCEATGG 1073 HSP 3 Score: 102.834 bits (255), Expect = 1.661e-21 Identity = 91/350 (26.00%), Postives = 154/350 (44.00%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRS----QFNCPLQCGKNAHFSEKANPCPRTCENHF--FGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A DPHY T+DG F G C YTL ++ + P F + +N G + + + V + ++ + ++ G ++VNG +P D + +++S V+ ++V+++ + VEV+ + K+ G+CG+ N D+F + GR V++ G S+ V+ G C +C + + +CG+L P+ PF+ C V +++ CV D+C E ++G C G +WR+ Q +CPL ++H+ + CP +C G RPC EGC C+RGY+ GA CV C C
Sbjct: 1097 CRAWSDPHYVTFDGLAFDFQGACTYTLARNCSRELP-RFEVRARNGNLGSSA-VSVPRQVTVTVYGQQVDIFAGDGANVQVNGLNRNLPVSHDDGRLSVYRSGSS-TVVSTDFGLQVSYNHRYHVTVEVASTFQSKLCGLCGNYNLNATDEFLSPEGRPVADPVQ----FGISWRVND-GSVCHDGSGTP--PVCDPEQRALYGSDGYCGILTSPDGPFAGC--HATVSPDSYYNSCVFDLCALGGGADLLAGA-LEAYTG---ACQSDGGPVEEWRNDTLGQHSCPL----HSHYELCGSACPSSCAQLTGPAGCHRPC-----GEGCQCDRGYVWSGAECVSVAQCGC 1421 HSP 4 Score: 95.5153 bits (236), Expect = 2.649e-19 Identity = 94/338 (27.81%), Postives = 143/338 (42.31%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCS---------FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRC--SVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVR-CEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPR-TC-ENHFFGTKRPCYDLPEREGCACN 1195
+C+ DPHY T+DG V+H+ G C Y + + PC F + ++N+ RG ++ V + + L + VLKVNG + +P ++ V + S + FV R +V V +D A VEV Y+ ++ G+CG+ NG RDD T SG + R G S+ C+ D C ++ + HCGVL +P PF C VD + + CV D+C + KV+ C A+ C AG + WR C HF ++PC +C E + G+ Y GC C+
Sbjct: 1480 RCTVTNDPHYFTFDGAVVHYQGVCAYDVAR------PCGGSGGEPYPFFRVVMENKRRGTGA-VSFISGVHLIVGSAHVLLRGREVLKVNGMRTLLPVVVAEGVAL--SEEASGFVVARTPHNVTVRYDRLYTAHVEVGAEYAGRLCGMCGNYNGDPRDDLLTPSGEIALDARQ----FGRSWRAPDVDAGCEDTVDHVEPGRCNEE-----EMWGHCGVLSDPEGPFRSC--HWFVDPALYLESCVYDLCSYEA-----TKVQLCRALEAYAQACGLAGVPLVDWRGPSGC--------HFIPASDPCSAISCGEREWCGSNSGIY------GCYCD 1778
BLAST of VWFD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000000971.1 (pep scaffold:Pmarinus_7.0:GL476384:436886:486709:1 gene:ENSPMAG00000000871.1 transcript:ENSPMAT00000000971.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 125.561 bits (314), Expect = 1.318e-28 Identity = 91/359 (25.35%), Postives = 165/359 (45.96%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNRED-DPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVS----------KPGHHCKKAKDISYHSI---CGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+ CS GDPHY+T+D ++ HF G YTL Q ++ + I +N+ G N ++ +V I+++ + + ++NG ++ P ++ + I + + + A + V F+ S+A V + Y+ ++ G+CG+ NG + D+FKT G V+++ ++ GN++ V+ P K+ + + + C + L+ K CGV +P PF +C VD ++ +C+ DMC N +++ C C + G WR C QC + + E+ + CP TC + C +LP+ EGC C G++ G C+ C C+
Sbjct: 689 YSTCSISGDPHYQTFDKRLYHFMGRETYTLVQSCGDNKNLLPIRILGKNKRVGHNHRVSFLDAVYIYVYGFKIKFTDRKDFELNGVRTKPPSNPTEGLEIVHTSRKMVLRADF-GLAVIFNRKSHADVTIPSSYAGQVCGLCGNYNGDKSDEFKTPDGSLVTSE----NVFGNTWEVNDRRSLFEQYESPVFRSKRLVEEPRNDLNLSCSDEQWAELENKNSCGVFHDPAGPFVQCWIPAPVD--PYYTNCMYDMCENIGD----KELFCSSLEVYTSACQQEGITPNNWRIHTGCAQQCAAHNIYVERMSACPSTCGD--LAASSNC-ELPDVEGCQCMPGFVMSGFDCIPFTQCGCL 1033 HSP 2 Score: 124.02 bits (310), Expect = 3.863e-28 Identity = 98/348 (28.16%), Postives = 154/348 (44.25%), Query Frame = 2
Query: 215 KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEK-SDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPE-REGCACNRGYIRDGALCVKPMHCKC 1249
K + C GDPHY T+D +I + G C YTL + + F I +NE G +Y K VI+ + L ++ + V+ + + P E V+I S ++ + V V FDG + + Y K+ G+CG+ N DD+ +G+ ++ + +G+S+ G K H I D I KK C V++ + F+KC +D F + C+ DMC + + C+ F AE C G I WR++ CPL C N H++ A+PCP TC + + + C EGC C++G++ LCV C C
Sbjct: 302 KGYATCHVAGDPHYFTFDLIMISYMGTCTYTLVDVCTDTNVTPFTITAKNEEHGQAS-GSYLKHVIVDIAGHRVTLQKRHRMLVDDKRVKTPIEDLVPGVKIGISGSYV-LLETDFGVTVKFDGKHHLEINTPSTYFNKLCGLCGNYNQNGTDDYLMPNGKLATSA----AQLGDSWKAE--GDDDAGCKPDEPH-IPSCDPINEEAYKKMCEVVISTSGAFAKC--HAEIDPEPFLKTCIYDMC----QFHGMESTLCDNFQAYAEACRAKGIN-ILWRNETFCPLPCLLNTHYTPCASPCPATCSDIY--AEASCQSAARCAEGCVCDQGFVLSDDLCVSLEACGC 631 HSP 3 Score: 98.5969 bits (244), Expect = 2.196e-20 Identity = 66/234 (28.21%), Postives = 101/234 (43.16%), Query Frame = 2
Query: 560 SVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
++ V FDG+ + + V Y+ + GICG+ NG D K V+ + +GNS+ CK D C + + CG++ +PN F +C + + FF +CV D+C P C+ A+ C++AG + WR+ CPL C +H+ A PCP TC N G C EGC C+ G++ G CV C C++
Sbjct: 31 NLVVRFDGNHHVEIVVPNEYAGILCGICGNFNGDGSDDNLKPDGSVAASSAE---LGNSWQSVNSLDECKD--DDGGRPECDPATQEEFEKEGFCGLITDPNGAFKEC--HAVLPPQVFFDNCVFDLCATGGNPLSL----CQALQAYADQCAQAGVI-VTWRNNTFCPLTCKPGSHYESCAPPCPATCSNTSLPGGCNHLC-----GEGCVCDDGFVLSGDKCVPAEQCGCLD 247
BLAST of VWFD domain-containing protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004575.1 (pep scaffold:Pmarinus_7.0:GL480782:524:24919:1 gene:ENSPMAG00000004167.1 transcript:ENSPMAT00000004575.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 117.857 bits (294), Expect = 4.356e-27 Identity = 93/346 (26.88%), Postives = 150/346 (43.35%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFF--GTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+DG + F G C YT + N FN+E NEYR ++ + V ++ + L L +N +L P + + S +L + ++ V F+GD+ A V V + Y++++ GICG+ NG R D++ G S+ +GNS+ + S+ W+ + C +++E F++C V+ F CV+D C + C A+ C+E G I WR+ C +C ++H+ A PCP TC N ++PC EGC C+ G++ G CV C C++
Sbjct: 1 CIVHGDPHYVTFDGLSLAFMGTCTYTTAKLCNSSSHLPYFNVETTNEYRNQGS-ISFVREVHTEVYGQNITLSLGRTLLLNEELVTPPLVLPG-LHVSLSGSYLVLMT-DFNLIVRFNGDNRAEVTVPREYAEELCGICGNFNGDRTDEYLMPDGTQASSPTE----LGNSWKTDNSSAYITL-------SLASGLWLWT------CTIVIERTGLFTEC--HAVVNPEELFTSCVLDQCWTYGD----KGTLCGSLQAYADECAENGIV-IMWRNATFC-RECKPDSHYESCAPPCPATCSNVTLPGACQQPC-----GEGCVCDEGFVFSGDKCVPQDQCGCLD 313 HSP 2 Score: 59.6918 bits (143), Expect = 1.157e-8 Identity = 38/138 (27.54%), Postives = 62/138 (44.93%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRI-FKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGI 640
C GDPHY T+D +I + G C Y L D+ F I +NE RG +Y K V + + + L +K V+ +NG+ + P +S + F V + + FDG + + +S Y+ K+ +
Sbjct: 373 CHVAGDPHYFTFDSALITYMGTCTYQLVSVCNADNVTPFTILAKNEERGQPNA-SYLKHVYVDIGSDRIHLKKKNVILLNGKKVKTPMIESLVPGVQFSIIGSYVHVVTDFGLVIKFDGVHHLSITLSSAYANKVIAV 509
BLAST of VWFD domain-containing protein vs. Ensembl Nematostella
Match: EDO41876 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S312]) HSP 1 Score: 112.849 bits (281), Expect = 5.346e-26 Identity = 94/348 (27.01%), Postives = 154/348 (44.25%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYE-------LGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNK-RNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CS G HYRT+DG+ I F G C YTL Q F++ VQN+ + +++++++ + Y+ + G ++VNG PY K +V + K + + + + FDG S+ V VS +Y G+CG+ NG+ DD + V+NK + S+ + +P C+ +++ + AK+ C VLL N FS C K VD F + C D+C K +C+ + + C+ + WRSQ CP QC + +SE C +TC+ G + C++ +GC C G ++ C+ C C
Sbjct: 4 CSTWGQRHYRTFDGRHIDFIGKCSYTLAQDCIPGSD-QFSLHVQNDKTCGSAGMDCERALLLYIGEKTYKVRWLVHLISSHGAIRVNGAKVSAPY-KDTNVEVSKVHSYTIIRSQGDELGIKFDGASSIQVAVSHKYRNNTCGLCGNNNGIPDDDLLMA---VTNKPATSVAEFAESWAMPEPNEKCESPLEVTRDVCSNASSVIRDAAKRICMVLLSEN--FSACHTK--VDPVPFVKRCEEDVCSCKF--GEHSGCQCQALTEYSRACASREIM-LDWRSQHLCPKQCIQPKVYSECGPACVKTCDAD--GLQPTCHETC-IDGCHCPEGTVQTDNRCLPVNQCPC 336
BLAST of VWFD domain-containing protein vs. Ensembl Nematostella
Match: EDO33061 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7ST99]) HSP 1 Score: 102.449 bits (254), Expect = 7.176e-23 Identity = 72/248 (29.03%), Postives = 132/248 (53.23%), Query Frame = 2
Query: 215 KDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGV-RDDFKTKSGRDVSNKRN---KYSLIGNSYHVSKPGHHCKKAKDISYH-SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMC 943
+D C++ GDPHY+T+DG++ +F+G+CRY L R+ + F++ +++E R N+ KS+++H+ V L + V+KV+ + ++PY++ ++I + + F+ + V++ +DG+S V VS RY G+CG+ NGV DDF K+GR + R +SL G H +P + I+ S C + + +A+K C + + FS C V +++ C+ ++C
Sbjct: 52 EDMGICTSYGDPHYQTFDGRMFNFHGNCRYRLVADCRQGN---FSVRLRSE-RHHNQAVGEAKSLVVHIGSTVIHLQRGLVVKVDRKEVQLPYQRLPSLQIDR-KNFMITLLSETGVKIIWDGESYIEVHVSHRYRGNTCGLCGNFNGVPSDDFMMKNGRYARSDREFGKSWSLGG---HRRRPCLQRAPSPPIAEPISKCRRSALHHWRARKRCWPI---KSQFSNC--HPVVKPHKYYKACISEVC 286
BLAST of VWFD domain-containing protein vs. Ensembl Nematostella
Match: EDO44199 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RWN6]) HSP 1 Score: 95.9005 bits (237), Expect = 3.437e-19 Identity = 98/357 (27.45%), Postives = 151/357 (42.30%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK-----GVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCS--VRVAFDGDSNAFVEVSKRY------SKKMNGICGDCNGVR-DDFKTKSGRDVS-NKRNKY--SLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C G H+ T+D Q FYG C Y N F + + N+ D TKSV +++ + LGQ+ G +KV+G +PY KS R+ ++V R S V + FDG ++V Y ++ G+CG+ +G +DF G + + N + S++ + + P K Y + G + A+K C V+ ++ FS C K VD R+F C+ D+C N SR C + S ++ C+ + WRS CP+ C SE ++ CPR C N + + +GC C G I+D CV P C C
Sbjct: 478 CYISGRGHFTTFDHQEYSFYGTCSYKALIDNSNVKQI-FQVVLNNDKNCDINA-PCTKSVDVNVDGKKVHLGQEVASRHGFVKVDGVTENLPYTKS----WPNIRQAGKYVIVRTSDEVLIYFDGSEELMIKVPDSYKTVNSSDTRLKGLCGNYDGNNTNDFIGLDGTTYTKDNINDFGVSMLDDPLCTNPP-----KPPSGCYSEVAGDVFSAMQNAEKMCSVIQ--SDAFSACRSK--VDFRDFKAQCIADVCA-CNSTSR-SDCMCNVLSTYSKACAWNHNITLSWRSPSLCPVTCPSGMEHSECSSACPRDCSN--MNSDPNACNSKCVDGCFCPEGKIQDRGKCVDPGQCSC 815 HSP 2 Score: 57.3806 bits (137), Expect = 1.579e-7 Identity = 85/361 (23.55%), Postives = 136/361 (37.67%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH--NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRS-------QFNCPL-----QCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER---EGCACNR--GYIRDGALCVKPMHCKC 1249
C+ VG+ H+ T+D + +G C Y L++H D F I ++ G + V G VL NG+ + S + + V + + + G NA++ V + + G+CG N DDF T RD N+ + Y+ VS +C ++ C AK C +++ N PF C R V ++ +Q CV D C+ K+ C + + A+ C++ G WR +F CP QC ++ + K CP TC++ T P R EGC C + + + CV C C
Sbjct: 853 CTMVGNSHFTTFDSRSYSMHGQCDYVLSEHCHFSNDTTKQFTIHIKISSDGSRQLIVSLAGATPVTLGGVE--GSPTVLNSNGKAT------SHILSVEHIGVQNVLVHAYAGLTILWTG-YNAYITVGPDFKSQTCGLCGTFNQNDADDFHT---RDGDNEADAYAFAQEWQVVSSVAASNCHRSNWNQLDQPCSTYSSNEGYAKSGCNAIIDLNGPFKACHRY--VPPQDMYQKCVKDGCMCKD-------CLCSVAAAYAKACADKGIVIDGWRDTISVCKPKFVCPAGTVLKQCNRDP-LTRKLR-CPSTCDDLANVTDT----CPSRRCVEGCYCEKEGELMNNEHKCVDKTQCPC 1186
BLAST of VWFD domain-containing protein vs. Ensembl Nematostella
Match: EDO41877 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S313]) HSP 1 Score: 61.6178 bits (148), Expect = 2.760e-9 Identity = 74/301 (24.58%), Postives = 129/301 (42.86%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--------SFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQ-KGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVS--KRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKR---NKYSLIGNSYHVSKPGHHCK--KAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGK 1081
C+A GDPHY+T+DG++ F G C Y ++ D C SF I+ +N G + T TKSV + + + + + K V V S P + + ++ AP + V +D + ++E+S ++ K+ G+CG+ +G + +D+ K+G ++ + + G+ +P H CK K ++ H+ C I K C + ++P+ + +C CV D C + + CE + A C AG +KWR +CGK
Sbjct: 74 CTAFGDPHYKTFDGRLYSFQGGCNYVMST-----DKCPGSKLTLQSFRIDAENIPCG-SAGVTCTKSVTVTLHDTIIHMVRGKAVPSVTKVSSLSPVHAR--YELVYAGLYVIIKAPF-GLNVIWDRGTRLYIELSPDSQHWSKVCGLCGNFDGDMTNDYMAKNGITETSPYPFGDTWRARGDCTKTMEPIHPCKQNKHRESKSHAACA---IIKSGTFKPCHISVDPDPYYERCR-------------CVYDTCGCDSVGD--CECTCEAIAAYAYECLAAGVV-VKWRQD-----KCGK 341
BLAST of VWFD domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000006964.2 (alpha-tectorin-like [Source:NCBI gene;Acc:105358719]) HSP 1 Score: 155.606 bits (392), Expect = 7.251e-37 Identity = 110/369 (29.81%), Postives = 174/369 (47.15%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVS---KPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
VC P+ Q +C++ ++ C S GDPHY T+D V HF G C Y L++ + P + IE +NE+RG + + ++T+ V + ++ E EL G G KVNG + P+ + V++++S F V+ + V++D S+ + + Y G+CG+ N DDF+T++G VS+ + NS+ S PG C+ + C HCG+L + PF+ C + + +NF Q CV D+C+ +Q + C+ A C + G + WR C + C N+HF +A CP TC N P LP +E C C+ GY+ CV C C
Sbjct: 213 VCMPY--SFQFSCQTVQRRTCTIS--GDPHYYTFDDTVFHFQGTCTYVLSEQCQYGLP-YYRIEGKNEHRG-STHVSWTRLVKVFVYNETIELVKGNPGRAKVNGTFTATPFTLNQGRVQVYQS-GFSVVVSTDFGLTVSYDTYSHVGISLPYTYQNATCGLCGNFNNQPGDDFQTRNGEVVSSDVD----FANSWRASGDEDPG--CEAQCRGLECAGCNAAQTALYNNNDHCGILQNSSGPFAACHQT--LPPQNFVQSCVYDLCIGGG----YQPILCQSLGVYASQCQQNGIQPASWRRPGFCEIPCPANSHFESQATGCPSTCVNPNSTQNCP---LPVQESCVCDTGYVLSAGQCVPYAQCGC 559 HSP 2 Score: 108.997 bits (271), Expect = 9.591e-23 Identity = 87/352 (24.72%), Postives = 147/352 (41.76%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEK-SDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKR--YSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSR-WQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ + C G Y+T+DG + G C+ + + D FN+ + +G + Y + +G KV+GQLSR+P+ S+ IF S + R S + FV V+ Y+ + G+CG+ N DDF+T G V + + + G+S+ HC + + ++ + + + +CG+L P+ PF+ C N + +D+CV+ R S + C++ +C + G +WR+ C C N+H CP TC + F C D P ++GC CN G++ +G CV P C C
Sbjct: 612 RPNGYATCLIRGPGSYQTFDGLTYQYPGACKLIVAKVIGSSDHPHFNVSTEKVPQGQESFSNYLN------------IEAQGA-KVDGQLSRLPFSSASNQFHIFHSNT--HSIILRTSFGLTVQTVWPHFVRVTAPVVYTSSLGGLCGNYNNEPNDDFQTPDGTLVHSVQ----VFGDSWREGSLASHCVENTN--------RNIMTNFNSSDYCGILSSPHGPFTPCWPVVNPSQQ-------VDVCVDILRRSEDPESTLCQVLRDYVLMCQQKGVSLGEWRNTTGCAATCPSNSHSEVCGTSCPSTCPSLSF--PFSC-DTPCQDGCQCNDGFVLNGNRCVPPTSCGC 926 HSP 3 Score: 102.064 bits (253), Expect = 1.275e-20 Identity = 97/356 (27.25%), Postives = 144/356 (40.45%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQN-EYRGDNKYFTYTKSVIIHMFR---------EVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIR---SLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CSA GDPHY T+DG+ F G CRY L + + F++E +N + G T +V + ++ EV K +L + Q +P+ + ++ +F S + FV + V +DG S + M G+CG+ N DDF + G V+ G ++ V PG++ S CG R A+ C V+ + P S C +VD FF DCV D+CV N + + C C A WR C + C N+H+ C TC + T + C EGC C+ G++R G CV C C
Sbjct: 988 CSASGDPHYLTFDGKTYDFQGTCRYVLAEVCHSSSGLHQFSVEAKNMPWNGLPVSITAEVAVTVWGYKVWMFSNNRVEVSICLNKTLLIILYQ--NLPFVLNGNISVFAS-GYQTFVRTSFGLSVMYDGWSTV---------RNMCGLCGNFNDNPNDDFHSPDGAAVTTP----DAFGAAWKV--PGNY-------SCSDGCGSSCPRCTNDQAARVQCEVIQAADGPLSFCHE--HVDPAPFFSDCVFDVCVGGNARN---DLLCRAIETYVSACQSANARIYPWRQNTTCSINCPANSHYELCGTDCGHTCVSSTNATCEHAC-----SEGCFCDEGFVRSGTTCVPEESCGC 1308 HSP 4 Score: 96.6709 bits (239), Expect = 5.267e-19 Identity = 78/303 (25.74%), Postives = 123/303 (40.59%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKD-FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNRE-DDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPL 1069
CTP + T N + D C+ GDPHY T+DG + HF G C Y +T+ ++ F + N +RG+N V V+G +P ++ F+ F A + V FDG S V +S+ Y K++G+CG+ NG D K K ++ ++ G+S+ P C +I+ C S + + C ++ + PFS C D + FF CV D+C+ S + C S + C+ G +WR +C L
Sbjct: 1344 CTPAQQCTVRNGQLGCYDGMSTCTVWGDPHYITFDGALAHFQGTCSYIITETGSHGNNHTQFEVVATNNHRGNNH-----------------------VSFVDGSDVSLPTTVGGIAQVSTQGGFVVFNA--ADLIVQFDGQSTLLVRMSQHYQNKVSGMCGNFNGDPSDDKVKPSGTLAQNDTEF---GHSW--KSPSSQCGSTDEINEDGHC----RFSQEYSELCSIITNTSGPFSACHLHS--DPQPFFSSCVYDLCLY----SPANGMLCSAVSAYEKTCTVLGLNIPEWRPALHCAL 1606
BLAST of VWFD domain-containing protein vs. Ensembl Medaka
Match: FCGBP (Fc fragment of IgG binding protein [Source:NCBI gene;Acc:101155957]) HSP 1 Score: 149.828 bits (377), Expect = 4.630e-35 Identity = 97/346 (28.03%), Postives = 164/346 (47.40%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHV-SKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ C+A GDPHY T+DG+ +F G C Y L ++ FN+ V+NE RG +K ++TK+V ++ + ++ K+NGQL+ +P + +D++ +F S + + + +D S V V Y M G+CG+ NG DD ++G+ ++ +G S+ V S PG C A + C + +A + CG++ + PF +C + VD + +DCV D+C C+ C G WR+Q CP++C N+H++ A+ CP TC + + C+ + E C C++G++ G CV C C
Sbjct: 1626 YATCTASGDPHYHTFDGRRFNFQGTCVYQLAGLCSQHPGLVPFNVTVENENRG-SKAVSFTKTVTFSIYGSTLTISKENPYKLNGQLAALPLKSNDELAVFLSGS-QAVIETAAGITITYDWWSTVRVTVPSNYHGAMCGLCGNYNGKALDDMTMQNGKTTPDEAK----LGESWQVASVPG--CSSACQGPWCQACSDSQKKVYQASQFCGIIADETGPFRECHKF--VDPAAYVEDCVYDVCQFHGH----HGSVCKAVEVYLSACQSQGIPIHPWRTQAFCPMECPANSHYNLCASGCPTTCAS--INSLTTCH-MHCSEACECDQGHLMSGDTCVPVRDCGC 1954 HSP 2 Score: 135.961 bits (341), Expect = 8.225e-31 Identity = 104/356 (29.21%), Postives = 166/356 (46.63%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPC--SFNIEVQN---EYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVR-DDFKTKS---GRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPER--EGCACNRGYIRDGALCVKPMHCKCIN 1255
C A GDPHY ++DGQ F G C Y L++ +D +F+++V+N + K + T+ V + +F + K GVL VNG L+ +P +D +V++++ +A + V +D + V V Y K+ G+CG+ NG R DDF+ +D+ ++ G S+ V+ P C+ + + C +CG+L P PF+ C K +D +++F DCV D+C + KV C+ + A C AG WR+ CP++C N+H+ A C +C C PE EGC C+ G++ DG CVK C C +
Sbjct: 817 CRASGDPHYTSFDGQKFDFQGTCTYVLSKSCGVEDTHLEAFSVQVENVQWDRMKGKKKVSVTRLVAVEVFGFTLIMKSKMFGVL-VNGVLNNIPLNLNDGEVQVYQEGTNY-LIATNFGLLVTYDLVYHVTVTVPGNYRDKVCGLCGNFNGDRKDDFQMPDQILAKDI-------NVFGKSWKVAIPNVVCENGCQGNECADCDPAHKDVFSKPAYCGILTAPKGPFAVCHSK--LDPQSYFDDCVFDVCASNGD----GKVLCDSVAAYAYNCHMAGVNVNDWRTPSFCPMKCPANSHYEVCAETCTYSCPG--LSDMVQC---PEACTEGCVCDAGFLYDGQTCVKETECGCYD 1152 HSP 3 Score: 135.961 bits (341), Expect = 8.435e-31 Identity = 109/351 (31.05%), Postives = 167/351 (47.58%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSK-PGHHCKKAKDISYHSICGK-DWIRSLKAKKH--CGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCI 1252
+ C A GDPHY T+D + F G C Y L +++ + F + VQNE+RG N +YTK V I +VY L +N QL +P + V ++KS F V ++V+F+ S AFV + Y + G+CG+ NG ++DD K+G N K + G S+ V++ PG C + +C D + ++ +K CG++ + PF C K VD FF+DCV D+C+ + R + V C+ + C G WR+ C ++C ++H+ A+ CP +CE P EGC+C+ GYI G CV C C+
Sbjct: 437 YSTCKATGDPHYVTFDNKKYDFQGTCVYQLAALCSKDTELTPFEVLVQNEHRGRN-VVSYTKLVQI----KVYSLN-----ILNDQLVNLPVSLVEGKVSVYKSGWF-AVVTTDFGLKVSFNWHSAAFVTLPSNYMGAVCGLCGNYNGNMQDDLTPKNG----NTPVKPTDFGTSWRVAEIPG--CIEG----CQGVCPSCDITQKVQYEKEDLCGIIRDTKGPFRDCHAK--VDPAGFFEDCVYDVCMYEGR----KDVLCQAVTAYTSACQGVGVNVYSWRTSNFCAVKCPIHSHYDICASACPASCEGL---APPPGCRAHCEEGCSCDEGYILSGDQCVPFSQCGCL 757 HSP 4 Score: 129.413 bits (324), Expect = 8.307e-29 Identity = 108/393 (27.48%), Postives = 180/393 (45.80%), Query Frame = 2
Query: 101 KEPCTNGTRNIRITTYVKDN-GVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKY-FTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSD-DVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLI--GNSYHVSKP--GHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLL-EPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
K+PC + ++ T V+ VC P T T C A GDPHY T+DG F G C+Y +++ + F+I +N+ RG+ F V I+ + Q G + VNG+L +P++ D +V +F+S V + + V++D + + +++ Y + G+CG+ NG D+ + SG+ V+ S+I G S+ GH C + + + C D K + CG L + N+ F C K +D + F +CV DMC+NK +++ C+ + + C + G WR +FNCP+ C + +H+ A+PC +C F K+ C E C C+ GY+ +C+ C C
Sbjct: 1205 KDPCKDANCRVQETCRVEGGEAVCIPKYTST-------------CWAWGDPHYHTFDGFDFDFQGTCKYIISKTCGNLNGLVPFSITERNDNRGNAAVSFVREVDVFIYDYNITIRKNQVGQVTVNGELLNLPFQLGDNEVSVFQSGS-SAVVETKFGLIVSYDWNWHLVIKLPSSYYSSVCGLCGNFNGDTGDELQNPSGKAVA------SVIEWGKSWQTPDQDKGHPCWDTCEKNCPT-CDDDERELYKTQAFCGGLAAKTNSVFKICNSK--LDPQAFMNNCVYDMCLNKGD----KRMLCQALTSYNKQCRDEGIIIKDWRKEFNCPMNCQRFSHYEHCASPCQPSCP--FPEQKQTCSGAC-VEACVCDEGYVLSAGVCIPAKTCGC 1567 HSP 5 Score: 128.257 bits (321), Expect = 1.559e-28 Identity = 97/349 (27.79%), Postives = 157/349 (44.99%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDD-PCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKD-ISYHSICGKDWIRSLKAKKHCGVLL-EPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTK--RPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A+GDPHYRT+DGQ F G C Y + ++ ED +F + QNE RG ++ +Y V + ++ + G ++V+ L +P ++ ++IF+S + + A + V +D N V + YS K G+CG+ NG +DDF T SG S G+S+ V + D + C + + + CG++ + N PF C +D + + ++C D+C+ K ++ C AE C AG + WR C +C N+ + + CP TC + +K RPC E C C G++ G+ CV C C
Sbjct: 47 CWAMGDPHYRTFDGQRFDFMGTCTYVIAKNCGEDSRLTAFEVHAQNENRGSHR-VSYVGLVTVQVYDTTITAVRSETGRVRVDNSLWSLPIILNNGKLKIFQSGRSVVIEADF-GLMVRYDWTHNLVVTLPDTYSGKTCGLCGNFNGNPKDDFTTPSGTQASGAV----AFGSSWKVPGLVADPQCRNDCVGGCGSCTESQLNKWDSDLSCGIITRKENGPFKNC--HAIIDPKAYLENCKYDLCMGKGL----RQFLCNALETYAEACQAAGVQIGDWRGLAKCSPRCPANSKYELCGSACPATCSDPDAPSKCQRPCV-----ETCTCKEGFVLSGSECVPATKCGC 378 HSP 6 Score: 122.479 bits (306), Expect = 8.819e-27 Identity = 99/349 (28.37%), Postives = 149/349 (42.69%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ--HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRK-FLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHF--FGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
KC A GDPHY ++DGQ F G C Y L + + ++ F + N G+ K + TKSV + + E ++N LS D R+ +R+ FV ++V +D V V Y KM G+CG+ N RD+F+ G+ N G S+ V P H C ++ +C K + CG++ P+ PF C K +D + DCV D+C +++ C C AG + WRS CP C N+H+ A+ C TC + C+ EGC C+ G++ DGA CV +C C++
Sbjct: 2014 KCVASGDPHYTSFDGQRFDFQGTCVYVLAKVCDDNDNQLTPFTVTQGNAKYGNGK-VSVTKSVTVTVNNE----------ELNLPLSL------DKGRLTVTREGHNTFVRTDFGLKVLYDTVYYVEVIVPSTYQGKMCGLCGNYNKKDRDEFRLPGGKGTKNVNE----FGKSWVVDLPEHICGGCEEDC--PVCEKANAVLYEKLDSCGIMKAPDGPFQACHSK--IDPAAYVSDCVFDVCAAGGS----KEILCNSVQAYVLACQNAGVQIQPWRSSSFCPASCPPNSHYEVCADTCRGTCASFIQQLTCSESCF-----EGCECDAGFVFDGAQCVPLENCGCVH 2328
BLAST of VWFD domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000044715.1 (alpha-tectorin-like [Source:NCBI gene;Acc:105358719]) HSP 1 Score: 148.673 bits (374), Expect = 9.358e-35 Identity = 109/369 (29.54%), Postives = 174/369 (47.15%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYEL--GQKGVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVS---KPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
VC P+ Q +C++ ++ C S GDPHY T+D V HF G C Y L++ + P + IE +NE+RG + + ++T+ V + ++ E EL G G KV G++ P+ + V++++S F V+ + V++D S+ + + Y G+CG+ N DDF+T++G VS+ + NS+ S PG C+ + C HCG+L + PF+ C + + +NF Q CV D+C+ +Q + C+ A C + G + WR C + C N+HF +A CP TC N P LP +E C C+ GY+ CV C C
Sbjct: 246 VCMPY--SFQFSCQTVQRRTCTIS--GDPHYYTFDDTVFHFQGTCTYVLSEQCQYGLP-YYRIEGKNEHRG-STHVSWTRLVKVFVYNETIELVKGNPGRAKV-GEVVSTPFTLNQGRVQVYQS-GFSVVVSTDFGLTVSYDTYSHVGISLPYTYQNATCGLCGNFNNQPGDDFQTRNGEVVSSDVD----FANSWRASGDEDPG--CEAQCRGLECAGCNAAQTALYNNNDHCGILQNSSGPFAACHQT--LPPQNFVQSCVYDLCIGGG----YQPILCQSLGVYASQCQQNGIQPASWRRPGFCEIPCPANSHFESQATGCPSTCVNPNSTQNCP---LPVQESCVCDTGYVLSAGQCVPYAQCGC 591 HSP 2 Score: 99.3673 bits (246), Expect = 9.812e-20 Identity = 92/347 (26.51%), Postives = 136/347 (39.19%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQN-EYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIR---SLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CSA GDPHY T+DG+ F G CRY L + + F++E +N + G T +V +++ P+ + ++ +F S + FV + V +DG S + M G+CG+ N DDF + G V+ G ++ V PG++ S CG R A+ C V+ + P S C +VD FF DCV D+CV N + + C C A WR C + C N+H+ C TC + T + C EGC C+ G++R G CV C C
Sbjct: 985 CSASGDPHYLTFDGKTYDFQGTCRYVLAEVCHSSSGLHQFSVEAKNMPWNGLPVSITAEVAVTVNL----------------------PFVLNGNISVFAS-GYQTFVRTSFGLSVMYDGWSTV---------RNMCGLCGNFNDNPNDDFHSPDGAAVTTP----DAFGAAWKV--PGNY-------SCSDGCGSSCPRCTNDQAARVQCEVIQAADGPLSFCHE--HVDPAPFFSDCVFDVCVGGNARN---DLLCRAIETYVSACQSANARIYPWRQNTTCSINCPANSHYELCGTDCGHTCVSSTNATCEHAC-----SEGCFCDEGFVRSGTTCVPEESCGC 1276 HSP 3 Score: 87.0409 bits (214), Expect = 5.203e-16 Identity = 76/306 (24.84%), Postives = 125/306 (40.85%), Query Frame = 2
Query: 167 CTPFRTKTQVNCESKRKD-FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNRE-DDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNK-------NRPSRWQK----VRCEIFSGLAEVCSEAGFEGIKW 1045
CTP + T N + D C+ GDPHY T+DG + HF G C Y +T+ ++ F + N +RG+N V V+G +P ++ F+ F A + V FDG S V +S+ Y K++G+CG+ NG D K K ++ ++ G+S+ P HC+ +++ S + C ++ + PFS C D + FF CV D+C+ + S ++K + IFS L++ C + +W
Sbjct: 1312 CTPAQQCTVRNGQLGCYDGMSTCTVWGDPHYITFDGALAHFQGTCSYIITETGSHGNNHTQFEVVATNNHRGNNH-----------------------VSFVDGSDVSLPTTVGGIAQVSTQGGFVVFNA--ADLIVQFDGQSTLLVRMSQHYQNKVSGMCGNFNGDPSDDKVKPSGTLAQNDTEF---GHSW--KSPNGHCRFSQEYS----------------ELCSIITNTSGPFSACHLHS--DPQPFFSSCVYDLCLYSPANGMLCSAVSAYEKTCTTITPIIFSALSDPCEQLNCAEHEW 1569 HSP 4 Score: 78.9518 bits (193), Expect = 1.201e-13 Identity = 77/352 (21.88%), Postives = 133/352 (37.78%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVR---DDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSR-WQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ + C G Y+T+DG + G C+ + + D FN+ + +G + Y L + Q ++V R++ S D N F ++ K DCN G++ DDF+T G V + + + G+S+ HC + + ++ + + + +CG+L P+ PF+ C N + +D+CV+ R S + C++ +C + G +WR+ C C N+H CP TC + F C D P ++GC CN G++ +G CV P C C
Sbjct: 644 RPNGYATCLIRGPGSYQTFDGLTYQYPGACKLIVAKVIGSSDHPHFNVSTEKVPQGQESFSNY--------------------LNIEAQGAKVTIGMDSSNRVWVS-------------------DYNIF-----QHPKP------DCNHGLKCPNDDFQTPDGTLVHSVQ----VFGDSWREGSLASHCVENTN--------RNIMTNFNSSDYCGILSSPHGPFTPCWPVVNPSQQ-------VDVCVDILRRSEDPESTLCQVLRDYVLMCQQKGVSLGEWRNTTGCAATCPSNSHSEVCGTSCPSTCPSLSF--PFSC-DTPCQDGCQCNDGFVLNGNRCVPPTSCGC 923
BLAST of VWFD domain-containing protein vs. Ensembl Medaka
Match: zanl (zonadhesin [Source:NCBI gene;Acc:101162078]) HSP 1 Score: 145.976 bits (367), Expect = 9.265e-34 Identity = 102/342 (29.82%), Postives = 168/342 (49.12%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSK-RYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+D + +F G+C Y ++ F + NE R ++ +Y K+V +++ + + GV++VNG +P + +V +F+S K V+ V V +DG N F+++ +Y K+ G+CGD NG +DDF+ G ++N N++ G+S++ C K + +I G + + +CG+LL+ N+PF+ C G V+ N+FQDC+ D+C + + + CE C + G + WR++ C L+C N+H+ A+PC TC C EGC C+ GY+ CVK C C
Sbjct: 1415 CIASGDPHYTTFDKRKYNFMGNCSYVMSGICNATSLPFFEVHADNENRYNSPTISYLKAVHVYVHMVKISILKGGVVQVNGTNVNLPVNPTPEVSVFQSGKHYT-VSMTFGVTVRYDG--NHFMDIKVIKYQDKLCGLCGDYNGNSKDDFQKPDGT-MTNDANEF---GHSWNTDP----CNKQPNA---TIPGCEPGEQELYEGYCGILLDKNSPFAVC--HGKVNPNNYFQDCLFDLCELEGA----KPILCEAIEAYVNECQDRGVDIGPWRNETFC-LKCPSNSHYEPCADPCQDTCSGKPSSCGGAC-----SEGCVCDPGYVLSAGKCVKSDSCGC 1730 HSP 2 Score: 145.206 bits (365), Expect = 1.263e-33 Identity = 103/373 (27.61%), Postives = 163/373 (43.70%), Query Frame = 2
Query: 146 YVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQ-HNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYH-SICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINL 1258
YV +G C V + + DF +C+ GDPHYRT+DG H+ G Y LTQ HN + + +N RG NK ++ + ++++ QK + VNG+ P + I + K +Q + V FDG S + + + YS + G+CG+ +G+ + K V N++ G+S+ VS+ + D + S C + + + CG L +P PFS C + +QDCV D+C +++RC + A +C EAG + WR Q C L C N+ ++ +PCP +C + C EGC C G++ CV C C L
Sbjct: 3516 YVLSDGKCVSLDKCGCVGSDGEYHDFDRCTVSGDPHYRTFDGFTHHYQGPYTYVLTQDHNLQGSLKPLMVRGKNLRRGGNKRVSFLDEMYVNVYGVDVRFLQKKTVLVNGERVTPPLSPVRGLTITMNSKQMQLTT-DFGLTVRFDGKSRGVI-LPRTYSNSVRGLCGNYDGITRNEYMKPDGTVVRDLNEF---GDSWRVSR---DTETDPDSGFETSDCSQSELDDYTSVTKCGALSDPEGPFSACHAALPPQI---YQDCVFDLCAEDGS----EELRCASYEAYATICQEAGVKLGSWRQQLGC-LPCPANSTYTACMSPCPSSCAD--LAAPSECDATACVEGCQCAAGFVMSEGACVPYPECGCTFL 3870 HSP 3 Score: 144.436 bits (363), Expect = 2.196e-33 Identity = 102/342 (29.82%), Postives = 165/342 (48.25%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSK-RYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+D F G+C Y ++ F + NE R ++ +Y K+V +++ + + GV++VNG +P + +V +F+S K V+ V V +DG N F+++ +Y K+ G+CGD NG +DDF+ G ++N N++ G+S++ C K + +I G + + +CG+LL+ N PF+ C G V+ N+FQDC+ D+C + + + CE C + G + WR++ C L+C N+H+ A+PC TC C EGC C+ GY+ CVK C C
Sbjct: 2233 CIASGDPHYTTFDKHRYDFMGNCSYVMSGICNTTSLPFFEVHADNENRYNSPTISYLKAVHVYVHMVKISILKGGVVQVNGTNVNLPLNPAPEVSVFQSGKHYT-VSMTFGVTVRYDG--NHFMDIKVIKYQDKLCGLCGDYNGNSKDDFQKPDGT-MTNDANEF---GHSWNTDP----CNKQPNA---TIPGCEPGEQELYEGYCGILLDKNGPFAVC--HGKVNPNNYFQDCLFDLCELEGA----KPILCEAIEAYVNECQDRGVDIGPWRNETFC-LKCPPNSHYEPCADPCQDTCSGKPSSCGGAC-----SEGCVCDPGYVLSAGKCVKRESCGC 2548 HSP 4 Score: 144.436 bits (363), Expect = 2.490e-33 Identity = 102/342 (29.82%), Postives = 165/342 (48.25%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSK-RYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
C A GDPHY T+D F G+C Y ++ F + NE R ++ +Y K+V +++ + + GV++VNG +P + +V +F+S K V+ V V +DG N F+++ +Y K+ G+CGD NG +DDF+ G ++N N++ G+S++ C K + +I G + + +CG+LL+ N PF+ C G V+ N+FQDC+ D+C + + + CE C + G + WR++ C L+C N+H+ A+PC TC C EGC C+ GY+ CVK C C
Sbjct: 435 CIASGDPHYTTFDKHRYDFMGNCSYLMSGICNATSLPFFEVHADNENRYNSPTISYLKAVHVYVHMVKISILKGGVVQVNGTNVNLPLNPAPEVSVFQSGKHYT-VSMTFGVTVRYDG--NHFMDIKVIKYQDKLCGLCGDYNGNSKDDFQKPDGT-MTNDANEF---GHSWNTDP----CNKQPNA---TIPGCEPGEQELYEGYCGILLDKNGPFAVC--HGKVNPNNYFQDCLFDLCELEGA----KPILCEAIEAYVNECQDRGVDIGPWRNETFC-LKCPPNSHYEPCADPCQDTCSGKPSSCGGAC-----SEGCVCDPGYVLSAGKCVKRESCGC 750 HSP 5 Score: 121.324 bits (303), Expect = 2.128e-26 Identity = 101/346 (29.19%), Postives = 150/346 (43.35%), Query Frame = 2
Query: 221 FCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
F C GDPHY T+D F G C YTL + R D P F++E +NE RG + +Y K + + + L + VNG+ P+ S + + S +++ + +RV +DG+ +A + V Y +M G+CGD +G +DF G N + GNS+ + C C + + CG + +P+ PF +C G VD FFQ CV DMC V C+ + C AG WR+ C L C N+ +S + CP TC G+ C D+ EGC C+ G+I CV C C++
Sbjct: 806 FQDCIVSGDPHYNTFDKNYYTFMGTCTYTLARTCRNDSP-WFSVEGKNEERGVSG-VSYLKKLYVTVNNITVTLMKSRTTLVNGKRVAFPHNPSPLMSLSLSGQYV-ILQTTFGLRVRWDGNHHAQISV-PSYHDQMCGLCGDYDGNAGNDFTKPDGTPAGNVND----FGNSWQTEEDEDECSPGTTPDLD--CDPELEAEVTKPDKCGKIEDPSGPF-ECI--GVVDPEPFFQSCVYDMCQFNGE----LHVLCDQLQAYTDACQSAGVTVHHWRAPDFC-LDCPANSSYSLCVSSCPETCLG-VVGSPG-CEDV-CVEGCECDPGFILSDDKCVPLKDCGCVD 1130 HSP 6 Score: 119.783 bits (299), Expect = 6.649e-26 Identity = 100/343 (29.15%), Postives = 150/343 (43.73%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCIN 1255
C GDPHY T+D + F G C YTL + R D P F++E +NE RG + +Y K + + + L + VNG+ P+ S + + S +++ + +RV +DG+ +A + V Y +M G+CGD +G +DF G N + GNS+ + C C + + CG + +P+ PF +C G VD FFQ CV DMC V C+ + C AG WR+ C L C N+ +S + CP TC G+ C D+ EGC C+ G+I CV C C++
Sbjct: 1790 CIVSGDPHYNTFDKKFYSFMGTCTYTLARTCRNDSP-WFSVEGKNEERGASG-VSYLKKLYVTVNDITVTLMKSKRTLVNGKRVAFPHNPSPLMSLSLSGQYV-ILQTTFGLRVRWDGNHHAQISV-PSYHDQMCGLCGDYDGNAGNDFTKPDGTPAGNVND----FGNSWQTEEDEDECSPGTTPDLD--CDPELEAEVIKPDKCGKIEDPSGPF-ECI--GVVDPEPFFQSCVYDMCQFNGE----LHVLCDQLQAYTDACQSAGATVHHWRAPDFC-LDCPANSSYSLCVSSCPETCLG-VIGSPG-CEDV-CVEGCECDPGFILSDDKCVPLKDCGCVD 2111 HSP 7 Score: 117.472 bits (293), Expect = 3.735e-25 Identity = 103/374 (27.54%), Postives = 159/374 (42.51%), Query Frame = 2
Query: 191 QVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQG 1309
++ C +D C GDPHY T+D + F G C YTL + R D P F++E +NE RG + +Y K + + + L + VNG+ P+ S + + S +++ + +RV +DG+ +A + V Y +M G+CGD +G +DF G N + GNS+ + C C + + CG + + + PF +C G VD FFQ CV DMC V C+ + C AG WR+ C L C N+ +S + CP TC G+ C D+ EGC C+ G+I CV C C++ + +W +G
Sbjct: 2597 ELGCYPSSQD---CIVSGDPHYNTFDKKYYSFMGTCTYTLARTCRNDSP-WFSVEGKNEERGASG-VSYLKKLYVTVNDITVTLMKSKRTLVNGKRVAFPHNPSPLMSLSLSGQYV-ILQTTFGLRVRWDGNHHAQISV-PSYHDQMCGLCGDYDGNAGNDFTKPDGTPAGNVND----FGNSWQTEEDEDECSPGTTPDLD--CDPELEAEVTKPDKCGKIEDLSGPF-ECI--GVVDPEPFFQSCVYDMCQFNGE----LHVLCDQLQAYTDACQSAGATVHHWRAPDFC-LDCPANSSYSLCVSSCPETCLG-VVGSPG-CEDV-CVEGCECDPGFILSDDKCVSLKDCGCVDTSGTYHPFQVDDEWLLEG 2946 HSP 8 Score: 116.701 bits (291), Expect = 5.774e-25 Identity = 80/279 (28.67%), Postives = 128/279 (45.88%), Query Frame = 2
Query: 230 CSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNC 1063
CS GDPHY T+D + H+ G C YTLT+ N D F ++ QNE+RG N +Y ++V+I+++ G+ ++VNG + P V+I+ S KF+ A +RV FDG+ +A V + YS + G+C + DD +N +G+S+ V P + + C + + CG++ +PN F C V +F++CV DMC + C+ A++C+ AG I WR+ C
Sbjct: 2989 CSVSGDPHYTTFDKRTHHYMGACSYTLTKLCNSSSDLPHFTVDTQNEHRGSNTKVSYVRAVVINVYGMTVVFGKGRSVQVNGTVVVPPVSSISGVKIYFSGKFVVLEA-SFGLRVRFDGNHHADVTLPSSYSGLLCGMCNFNDNPTDDNLKPDNTPAANSNE----LGDSWAVPDP----RPCTNGGGQEECDEKVEEEAQKPTSCGMITDPNI-FKPC--HAVVPPEPYFENCVYDMCATGGQ----TVALCQALESYADICAAAGVN-IPWRNSTFC 3250 HSP 9 Score: 77.0258 bits (188), Expect = 5.419e-13 Identity = 78/308 (25.32%), Postives = 123/308 (39.94%), Query Frame = 2
Query: 344 FNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYE-KSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCY-DLPER---EGCACNRGYIRDGALCVKPMHCKCI 1252
F + +NE RG + +Y +SV + + +NG+ R P + ++ S + + ++V FDG + + V Y K+ G+CG+ N D K + + + +GNS+ C+ H C + KA+ +L ++ F C + D F +C+ DMC Q C+ A+ C AG I WR+ C L C N+H+S+ PCP TC + F P + LP EGC CN GY+ CV C C+
Sbjct: 3260 FRVVAKNEERGQPEA-SYVRSVKVFL--------------LNGRRVRTPLTIDTIGAKVITSGSY-SLLDTNFGLQVKFDGVHHLEITVPGEYFNKLCGMCGNYNHDSTDDNLKPDKQPAKDVIE---LGNSWKSEGDSDPCQPDNRPDVHPNCTAEEEEQFKAQCEQVIL---SSSFRPCHSVVSPDA--FLGNCIYDMCEYNGM----QATLCDNVEAYAQACQSAGVT-ITWRNSTFC-LPCPPNSHYSDCTAPCPPTCSDLF-----PIFCHLPPTACVEGCECNAGYVLSDGKCVSLDKCGCV 3532
BLAST of VWFD domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000006984.2 (pep primary_assembly:ASM223467v1:19:4974111:4986611:-1 gene:ENSORLG00000004509.2 transcript:ENSORLT00000006984.2 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 138.658 bits (348), Expect = 9.379e-32 Identity = 105/369 (28.46%), Postives = 166/369 (44.99%), Query Frame = 2
Query: 164 VCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEKSDD-VRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVS---KPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
VC P Q +C++ + C S GDPHY T+D +V F G C Y L++ + + P F +E +NE+ G+ + ++T V + ++ E EL ++ G KVNG P+ D +++++S + V+ + VA+D + + Y G+CG+ N DD +T+ G VS+ + NS+ S PG C + + C HCG+L + PF+ C + + +NF CV D+CV +Q + C+ A C + G + WR C + C N+HF +A CP TC N P LP +E C C+ GY+ CV C C
Sbjct: 465 VCMP--ASFQFSCQTVPRRTCTIS--GDPHYYTFDDKVFSFQGTCTYVLSEQCQNELP-YFRVEGKNEHFGNTR-VSWTGLVKVFVYNETIELVKRTTGKAKVNGNFVAAPFSLLQDRIQVYQSGMSM-IVSTDFGLMVAYDISYYLRISLPYTYQNATCGLCGNFNNQPGDDLRTRDGEVVSSDV----VFANSWRASGDEDPG--CDAQCEGLGCAGCTAAQTALYSNNDHCGILQNSSGPFAACHQT--LPPQNFVDSCVYDVCVGGG----YQPILCQSLGVYASQCQQNGIQPQNWRRPGFCEIPCPANSHFESQATGCPPTCVNPNSTQNCP---LPVQESCVCDTGYVLSAGECVPYAECGC 811 HSP 2 Score: 111.309 bits (277), Expect = 2.073e-23 Identity = 97/344 (28.20%), Postives = 138/344 (40.12%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CSA GDPHY T+DG+ F G CRY L + N F++E +NE + + T V + ++ KV+G +P+ + + +F S + FV + V +DG S M G+CG+ N DDF T G V+ G ++ V PG++ S C D A+ C V+ + PFS C +VD F DCV D+CV N + C C A WR C + C N+H+ C RTC + T + C EGC C+ G++R G CV C C
Sbjct: 117 TCSASGDPHYLTFDGKTYDFQGTCRYVLAEVCNSSSGLHQFSVEAKNEPL-NGLPVSITAEVAVTVWG----------YKVDGITRNLPFVLNGTISVFAS-GYQTFVRTSFGLSVMYDGWSTV---------GNMCGLCGNFNDNPNDDFHTPDGAAVTTP----DAFGAAWKV--PGNYTCSDGCGSSCPRCTND----QAARVQCEVIQAADGPFSFCHE--HVDPAPFVSDCVFDVCVGGN---AGNDLLCRAIETYVSACQSANVRIYPWRQNTTCSINCPANSHYELCGTDCGRTCASSTDATCEHAC-----SEGCFCDEGFVRSGTTCVPEGSCGC 419 HSP 3 Score: 108.227 bits (269), Expect = 1.713e-22 Identity = 89/358 (24.86%), Postives = 153/358 (42.74%), Query Frame = 2
Query: 209 KRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNI---EVQNEYRG-DNKYFTYTKSVIIHMFREVYELGQK--GVLKVNGQLSRVPYEK-SDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKR--YSKKMNGICGDCNG-VRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSR-WQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
+ + C G Y+T+DG + G CR + + FN+ +V N +G N+ +++I + + Q V +V+GQL ++P+ S+ +RIF S + R S + FV V+ YS + G+CG+ N DDF+T +G V + + + G+S+ HC + ++ + + + CG+L P+ PF+ C + + +D+CV+ R S + CE+ A +C + +WR+ C C N+H+ CP TC + F D P ++GC CN G++ +G CV P C C
Sbjct: 864 RPNGYATCWIRGPGSYQTFDGLTYQYPGACRLIIAKEMGLSGHPHFNVITEKVPNILQGFSNQILNSETNLLIFPIMTLEKFSQSCFHVFQVDGQLYKLPFTSGSNQIRIFHSNT--HSIILRTSFGLTVQTVWPHFVRVTAPVVYSSSLGGLCGNYNDEPNDDFQTPNGTLVHSSQ----VFGDSWREGSLASHCVENTVLN---------PLNYSSTEFCGILSSPHGPFTPCWPVVDPSQQ-------VDVCVDILRRSEDPESTLCEVLRDYALMCQQQEVSLGEWRNTTGCAATCPSNSHYELCGTSCPSTCPSLSFPFS---CDSPCQDGCQCNDGFVLNGNQCVPPTSCGC 1196 HSP 4 Score: 108.227 bits (269), Expect = 1.787e-22 Identity = 96/344 (27.91%), Postives = 135/344 (39.24%), Query Frame = 2
Query: 227 KCSAVGDPHYRTYDGQVIHFYGDCRYTLTQH-NREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCN-GVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGT-KRPCYDLPEREGCACNRGYIRDGALCVKPMHCKC 1249
CSA GDPHY T+DG+ F G CRY L + N F++E +NE + + + EV V+G +P+ + + +F S + FV + V +DG S M G+CG+ N DDF T G V+ G ++ V PG++ S C D A+ C V+ + PFS C +VD F DCV D+CV N + C C A WR C + C N+H+ C RTC + T + C EGC C+ G++R G CV C C
Sbjct: 1257 TCSASGDPHYLTFDGKTYDFQGTCRYVLAEVCNSSSGLHQFSVEAKNEPW---------NGLPVSITAEV---------AVDGITRNLPFVLNGTISVFAS-GYQTFVRTSFGLSVMYDGWSTV---------GNMCGLCGNFNDNPNDDFHTPDGAAVTTP----DAFGAAWKV--PGNYTCSDGCGSSCPRCTND----QAARVQCEVIQAADGPFSFCHE--HVDPAPFVSDCVFDVCVGGNA---GNDLLCRAIETYVSACQSANVRIYPWRQNTTCSINCPANSHYELCGTDCGRTCASSTDATCEHAC-----SEGCFCDEGFVRSGTTCVPEGSCGC 1552
BLAST of VWFD domain-containing protein vs. Planmine SMEST
Match: SMESG000040823.1 (SMESG000040823.1) HSP 1 Score: 7522.93 bits (19518), Expect = 0.000e+0 Identity = 4026/4048 (99.46%), Postives = 4036/4048 (99.70%), Query Frame = 2
Query: 2 MWRQWLTLLIITLSFYQFAKATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCVLERKSRTIVINCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLXXXXXXXXXXXXXXXXXNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLXXXXXXXXXXXXFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSEXXXXXXXXXXXXXXVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYECCDXXXXXXXXXXXXRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEIKSRIKATFCEISKKRWVKHVICKPPYKTKVCYPKHNRLVIKTYFYVVXXXXXXXXXXXXXXXXXXXXXXXXXRSACGPRGDKGRRYLNVTIKRYRQTRQNKCKLIINRRIEVCECEKTKKMKLCKSGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSXXXXXXXXXXXXXXXTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPXXXXXXXXXXXXXXXXXXISTGLCTYVIRKYSVFIRKCKCYRKLIKVIKKERCCKKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKXXXXXXXXXLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXXXXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRKIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTTTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCXXXXXXXXXXXSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKYLSECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADCHP 12145
MWRQWLTLLIITLSFYQF KATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLC+LERKSRTIVI CKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLTCMRTCCCRKSKRCTTCNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLGTKTGKCDKTTCFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSERFSKSKCKCRKFRCVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFY+CCDEKSSETTKCKKKRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEI SRIKATFCEISKKRWVKHVICKP YKTK+CYPKHNRLVIKTYFYVVINCKCKLKVSK VK CV+CPKTKIIRSACGPRG+KGRRYLNVTIKRY TRQNKCKLIINRRIEVCECEK KKMKLCK+GQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSYRIVKCRCVRRVRYRTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPVKKVTKRKLRCRLRRRERISTG+CTYVIRKYSVFIRKCKCYRKLIKVIKKERCCKKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKYYIRRRYYRLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDT VQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTCDCKCRKNRKYRKCSRNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKR+RCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRKIYKYKIIKCKCRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDK QKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIR IFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTT+TDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCIDDIRIRTTIRSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKY+SECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADCHP
Sbjct: 1 MWRQWLTLLIITLSFYQFTKATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCILERKSRTIVIKCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLTCMRTCCCRKSKRCTTCNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLGTKTGKCDKTTCFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSERFSKSKCKCRKFRCVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYKCCDEKSSETTKCKKKRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEINSRIKATFCEISKKRWVKHVICKPRYKTKICYPKHNRLVIKTYFYVVINCKCKLKVSKIVKTCVECPKTKIIRSACGPRGEKGRRYLNVTIKRYIPTRQNKCKLIINRRIEVCECEKNKKMKLCKNGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSYRIVKCRCVRRVRYRTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPVKKVTKRKLRCRLRRRERISTGVCTYVIRKYSVFIRKCKCYRKLIKVIKKERCCKKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKYYIRRRYYRLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTTVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTCDCKCRKNRKYRKCSRNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRRRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRKIYKYKIIKCKCRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKFQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRNIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTSTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCIDDIRIRTTIRSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKYISECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADCHP 4048
BLAST of VWFD domain-containing protein vs. Planmine SMEST
Match: SMESG000040823.1 (SMESG000040823.1) HSP 1 Score: 7518.7 bits (19507), Expect = 0.000e+0 Identity = 4019/4048 (99.28%), Postives = 4028/4048 (99.51%), Query Frame = 2
Query: 2 MWRQWLTLLIITLSFYQFAKATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCVLERKSRTIVINCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLXXXXXXXXXXXXXXXXXNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLXXXXXXXXXXXXFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSEXXXXXXXXXXXXXXVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYECCDXXXXXXXXXXXXRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEIKSRIKATFCEISKKRWVKHVICKPPYKTKVCYPKHNRLVIKTYFYVVXXXXXXXXXXXXXXXXXXXXXXXXXRSACGPRGDKGRRYLNVTIKRYRQTRQNKCKLIINRRIEVCECEKTKKMKLCKSGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSXXXXXXXXXXXXXXXTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPXXXXXXXXXXXXXXXXXXISTGLCTYVIRKYSVFIRKCKCYRKLIKVIKKERCCKKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKXXXXXXXXXLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXXXXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRKIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTTTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCXXXXXXXXXXXSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKYLSECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADCHP 12145
MWRQWLTLLIITLSFYQF KATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLC+LERKSRTIVI CKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLTCMRTCCCRKSKRCTTCNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLGTKTGKCDKTTCFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSERFSKSKCKCRKFRCVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFY+CCDEKSSETTKCKKKRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEI SRIKATFCEISKKRWVKHVICKP YKTK+CYPKHNRLVIKTYFYVVINCKCKLKVSK VK C I RSACGPRG+KGRRYLNVTIKRY TRQNKCKLIINRRIEVCECEK KKMKLCK+GQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSYRIVKCRCVRRVRYRTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPVKKVTKRKLRCRLRRRERISTG+CTYVIRKYSVFIRKCKCYRKLIKVIKKERCCKKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKYYIRRRYYRLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDT VQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTCDCKCRKNRKYRKCSRNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKR+RCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRKIYKYKIIKCKCRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDK QKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIR IFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTT+TDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCIDDIRIRTTIRSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKY+SECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADCHP
Sbjct: 1 MWRQWLTLLIITLSFYQFTKATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCILERKSRTIVIKCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLTCMRTCCCRKSKRCTTCNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLGTKTGKCDKTTCFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSERFSKSKCKCRKFRCVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYKCCDEKSSETTKCKKKRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEINSRIKATFCEISKKRWVKHVICKPRYKTKICYPKHNRLVIKTYFYVVINCKCKLKVSKIVKTCECPKTKII-RSACGPRGEKGRRYLNVTIKRYIPTRQNKCKLIINRRIEVCECEKNKKMKLCKNGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSYRIVKCRCVRRVRYRTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPVKKVTKRKLRCRLRRRERISTGVCTYVIRKYSVFIRKCKCYRKLIKVIKKERCCKKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKYYIRRRYYRLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTTVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTCDCKCRKNRKYRKCSRNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRRRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRKIYKYKIIKCKCRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKFQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRNIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTSTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCIDDIRIRTTIRSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKYISECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADCHP 4047
BLAST of VWFD domain-containing protein vs. Planmine SMEST
Match: SMESG000040791.1 (SMESG000040791.1) HSP 1 Score: 3664.39 bits (9501), Expect = 0.000e+0 Identity = 1954/4023 (48.57%), Postives = 2717/4023 (67.54%), Query Frame = 2
Query: 77 VCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCVLERKSRTIVINCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLXXXXXXXXXXXXXXXXXNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLXXXXXXXXXXXXFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSEXXXXXXXXXXXXXXVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYECCDXXXXXXXXXXXXRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEIKSRIKATFCEISKKRWVKHVICKPPYKTKVCYPKHNRLVIKTYFYVVXXXXXXXXXXXXXXXXXXXXXXXXXRSACGPRGDKGRRYLNVTIKRYRQTRQNKCKLIINRRIEVCECEKTKKMKLCKSGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSXXXXXXXXXXXXXXXTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPXXXXXXXXXXXXXXXXXXISTGLCTYVIRKYSVFIRKCKCYRKLIKVIKKERCC--KKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKXXXXXXXXXLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXXXXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRKIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTTTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCXXXXXXXXXXXSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKYLSECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADC 12139
+C K+ K PC NG R + Y++ C P +KT +C K+K FCKCSA+GDP+Y+TYDGQV HFYG CRYT +++ DPCSFNIEVQN Y+ D+K F YTKSVIIHMF ++YELGQ LKVN +R+PYEK V+I +SR LQFVAP+C +RV FDGD+NA+V+VS RYS +MNG+CG+CNG DD KTK G DVS ++NKYSL+GNSY+VS G C AK++SY +C K+W++ KAKK CG L+E ++PF +C KG++ L+ F+++C+ID+C +P RWQK RCE+FSGLA+VCS+ G + WR CPL+CGKN+H S A CP TCEN+FFGTK PCY+ +EGC CN+GYIRDG+LCVKP HC+CI++CVDRE SE C+ WK +G CK+ S+AM IICPKTCGFC+ CED L ++CL+FR +GLC FYKA+CGLTCNYDKC CGK++ VGKC+ NRI TTH KF RD +G CAK++ +++ CNC KVTK CN CTG R + ++++ I NKCV +K+++ EKC KC + R +CI NR IK T F +L GC+ CV ++K T I CK+++ K D+ TC+++ K+I RRP+NC+C E V NR+ WCCNKKPK L P C+ G+IIHRTI+Y F +GC P KD IEIPKCK ++ KGKC R G FCKA D + K+N+ CKC+ KL RTCCC+K + TTCN +GI T V + L+KK ++ C+R K+ S TI+ KT+++ IKGKC +NCLRK+ I++KFR GC V +F + + R+CCC PKQ + I CI + IV KV++R K+N C +V+ + KK + CP VKE+KC++RR ++++T I Y ++KC+C +R + ++C C YK TK G C+K TC R Y FQN+ C+ K CCC R IK SYC+R RY ++K+WEFN KLR+CI ++ + A P C + +KG CG +KN+ K+IT E S CKC+K VTW C CP+ K K+ C G +I E + L K +KC+ +R V+CP + + K ++KC+YK YTG MKP NC+C W Y+CC + + K + I+TK + + ++ CI V R ++AITC +Y+ + +T+CK G+YW+ T Y V NCKC + R T KVIC+CIP T+KR C GAG + I TK+ LIN KCI +K F P +C + D KC+RKTG+ITV R+Y + CKCVR K T +VRCPCFRKDR+V+++C +R +E+QR K KCIWK IKS+ EDC+C R T C +H +R+ Y L+ T+ IPLQ+C K +K + ++CNR Y K C+ H+ IE +CIYEK NCRCVK C+ + GPC+C+RLNKC +KC+ N ++++C +K GR C KS+ I EKC KI+CKSCS+++NNG+++ C T++ Y NC+CV+K + +LCKC D +RP C+ NRK I+T SFY +KNHCV RKRQ F+ I+C P ++ KCST Y L Y+ ++ CKCVK I + NSKCC KP K C K HW T F Q+PT +KLFP IKS + ATFC+ KK W K + C Y C+ K +RL IK ++Y V CKC+LKV+ K + C CPK K+IRS CGP GRRY ++TI+ +R+ + NKC I +R EVC CEK+K + C G+R+F TIWYNI TKP CKP++ K++ISI C+N GRKNKWI + V CR G +T+K+FER +N K C+CK++ KS K+ ICCKP F CRNN EHI I + + LKC S K + C KP EVVGNC+GKVIRYR ++R V C+CV+ V YR +K D +CV++ +W+ + IPYKLI+G+C +I C L++FVD++I+ CTFKR +IGK K+C C D V +T+ILNY+CC+K++V +C ++ KV T SYRL+ FKC+PV K+ K ++C L+ ER STG CTY I YSVFIR CKCYRKL KVIKK CC KKP CD+ G KI + S+ H KDD C+K + S INC R+ C+K E +C+K T+ + ++C RK CKC++ KVKE + CCG F WIK+ +C Q+++ +IR RYY LK K C+AV+VKE + RC+CP + M CV + ++R Y+LK +C L S+K++ + CP+K K+++ C++KTGW+ +VYRI YPK+CKC++K + KEICICS+AFP+ KE+ CK +V++KR+A CT+ +VKW+IIT + I+HCKK K EIG CY+ + G A+SIRYD VQYF K CRCQRKV+KRILKHC C+ H S +C+ N + +SY + +G C +++ ++ KVPC KP I+K C +NKYI+T+ T++ KNC+C SI+RK+CDCKC ++RKYRKCS Y I E+++ Y K+ C C ++KS Q VP CPRFIV +KG C+ G YRE+I+R+L ++ + C C VKEVK K IC C + +K C SN ++E+W WK+N ++N+CE+YL SSN P C I+ CN KTG K++ YL++ C C K V+K +CKC + VLV+ G+C+ RP C RID YR E L KC + + V CCC K + Y +CE +N+ + I + L KCV+ EI+ S LKCS +++ KC +NG+K Y+++ L+NCKC+K + C+CRC+++ + IC RKR ++TI + L KCKC K S +I CP + S S C+R R TNYW+ +TRT + +N +C CV + +KICRC+ N+K K++C+AK H + TKF VL+NGQC+R+ T + ++C+GKWR+K+ SGC+P GFYG+KT+ YSKL+H+ C CKE++K+ CHCACSG S VCV E+IH K++ YKI KCKCRQL RSE VS VKC+++RPKI KC+I++NRCV++V H+ PYTI C+C YR + PC+TC C +T +KC SN +I C IL NG I+++V+ +E+ C + C+Q+TKC KK++TQ F C V +K NCKC+S+ ++ +PC CKP ++ GKCNRKTCL+++TR FHL+V N+ KC ++ R Y+++CCCP N KDV+KC NR +K ++ FDK +KTC+II+++ D TP+C+P V+ + GKC+K CL +++++C+C + + +R+CCC +KD+ + KC+ + V ++FVF+N KC + + + + ++ C+ S + R KCN T R ++ H + +KC+C+ + VKE+ C C TV +ICL KGI+R I SY+LNE+ N+CD+ ++NED+QI CN ++ C T NG +++CTT W +R+GCKC EQ+ WIFSL HC K ++ +C++N V KIYYVK+RS K YDY+CV+K K++ + + LC + Y + CI SF TYT+H++ R CQC+P K++RV C+C K + +C++ +IR T R+YKL CD K IP C+C+++D+ VD ++CPDD+F E C+ +RTWTTYDI+NCKCVA+ +T++R DCK +IC D+L+ +C IKK+GKC Q+N+Y QFLCP+TCGYCEKC IKKYLS+C CK +AGK+ICSR L+ +P G+KC ++VE+ CDC+N L N C KS++ G C +I+ KCAYHCN C+ C +N++YK CLQ G NKGKYE+LRI++FK++ +CFF RK+SYEG C+LC + K V SCF GKRFV+TK+V K GTCK E++ AYSC CC +I+T+I C + SRV+ I FW+N+KG C++ KV N Y C+ +C+ ++ V++ C+YNKQLV+KTWYSD +C+PH VYE+ C
Sbjct: 1 MCMAPKIIKGPCENGIRIVTTIKYLEVLRKCKPIESKTTESCGRKKKRFCKCSALGDPYYKTYDGQVFHFYGSCRYTFSKYKSVQDPCSFNIEVQNGYKSDDKTFPYTKSVIIHMFGQIYELGQGKTLKVNDNPTRIPYEKDKKVKISQSRDILQFVAPKCLIRVGFDGDANAYVQVSTRYSGQMNGLCGNCNGKHDDLKTKDGTDVSRRKNKYSLVGNSYNVSTTGKACAPAKEVSYEDLCDKNWLQYFKAKKFCGGLIEEDSPFKECENKGHIVLKQFYENCLIDLCSKTKKPKRWQKARCELFSGLADVCSDNGVAVLDWRKILVCPLKCGKNSHLSVNAKLCPETCENYFFGTKNPCYESSSKEGCNCNKGYIRDGSLCVKPTHCRCISICVDREKSENCKDWKSKGHCKQFSKAMKIICPKTCGFCQVKDETCEDYLRFKRCLKFRRQGLCTSAFYKAVCGLTCNYDKCGCGKKKTIVGKCNKHKNRIKTTHIKFVRDPRGICAKVVGYTYQVCNCKKVTKKVGSCNFCTGKRIVTMNVETINGNKCVTQKKIVFEKCKKCDLKSRFTEKCIANRVIKKTTIFNRLSGCFRCVKDQKFETREIKCKNSRIEKLDKRTCLKHIKVITRRPLNCKCVESVTNRKVVWCCNKKPKVLKPFCRKGKIIHRTIFYVFRNHGCQPAPKDKIEIPKCKQNKEKNKGKCHRLLKGVHFCKATDVTRISKVNNACKCVVEKLHHTRTCCCKKPRNYTTCNRLLGILTAVKVEHSLIKKADKFECLRKAKQTSTTIKQKTEYLEIKGKCHSNCLRKNKIVKKFRDGCTVKVQFVKFQTRICCCLPKQIRTIECIADCIVTKVFRREFKSNSCRKVLISNVKKSVVCPKPTVKETKCIFRRNKKRVTKIFYVVQKCRCVRRKLVKIEKCKDCLYKETKTKEGPCNKKTCQRVIYTNFQNKYCENSVKKSHSTCCCRQRPIKSSYCDRFTSYRYHVVKFWEFNPKLRSCISKTTKKAHRPICNKDKVIKGGCGTIKKNFRKLITIREIVSPLDCKCKKTEIVTWNRCSCPVGKTTKR-CVGETLEIIEVGFKLTKDESKCVANKSVKRQSVICPRVVRRHTKVLSKCSYKSYTGYMKPKNCKCTLHWNKVVLYKCCQKPKISSKCFKN-KTIITKITKFIVSKDKKKCIPSVIRKTVAITCPRYVNVEKTKCKKGIYWVTTTKYAVVNCKCVQTRKTGTKVICKCIPGHTIKRHCTGAGIKTITTKFTLINGKCIPAAKTEFNPTRCGGAVDKPGKCNRKTGMITVNRMYFEAVKCKCVRRKSTHSVRCPCFRKDRVVKKQCIN-MKRIVEVQRHKLHKSKCIWKTIKSFSEDCKCSRNSFKTECFKHAAFRSNFVNYQLRTVSTYQIPLQRCFKSNSQKTKPLLCNRDYSEKRCINHQLIETKCIYEKINCRCVKNCRMIKIGPCQCRRLNKCLQKCVNNRKFSICLTYKPGRISCEKSQKQTLIPEKCLPTKIQCKSCSVKRNNGIFKICIKTFYEYQNCECVKKQKPIHKLCKCDRDRNNRPYCLANRKAIDTISFYPIKNHCVERKRQTFLKIDCPAPVIKTDNGKCSTKYTLIYYEVKKCKCVKKVIEKTNSKCCRKPTINKMCSKDHWTFTQIHFQQKPTTLKLFPTIKSSVLATFCQTVKKNWRKRISCPKSYTITTCHVKTDRLEIKHFYYAVNGCKCELKVTTKFETCRPCPKKKVIRSKCGPIALMGRRYFDLTIRGWRKQKNNKCTSYIKKRKEVCLCEKSKNYEQCLQGKRVFTTIWYNIKTKPACKPSIEKRSISIPCYNNGRKNKWIPTKVVTCRRHGHFTVKHFERLEFNPKACTCKKVYKSTKIGICCKPCHFKTVCRNNNYEHISICQESKNLKCVKKLSKKIRTVTCEKPLKEVVGNCNGKVIRYRITTFRKVNCKCVKSVTYRNKIKPIDRRECVKN-TWKITRIPYKLIHGVCQRGKPQIISDSTVCIMLIKFVDRKINSCTFKRLYIGKTVKNCVCVDKVIRTEILNYKCCKKNIVKLSCMKDRVKVVTTTSYRLMGFKCYPVIKIAKADIKCHLKTEERKSTGKCTYKILNYSVFIRNCKCYRKLGKVIKKAHCCSHKKPFTKRLCDSLKGFKIIIQTSFHHKKDDTCVKFDKKTSIPINCKRLACSKIEGQCVKKTRNIQVFCFKRKGCKCVKVKVKELQTCCGKRFNWIKSDSCSQNRRDFIRTRYYALKFVPKTKLCQAVVVKETYKRCRCPSIASSMRCVKDNSYLIVRTSYVLKGNSCNLITSKKIIPVKKCPKKIITKIKETCNRKTGWKTIVYRITYPKNCKCLQKTFTKKEICICSIAFPNPKEKTSCKNHYIVVKEKRLASCTKTKVKWSIITNQLPILHCKKTKTEIGRCYKSKTGNAVSIRYDVVVQYFMKNCRCQRKVLKRILKHCTCKRTHSSIKCIGNKKIETTFSYVLVKGFCIKKINRNTIKVPCSLKPKISKFPCVKNKYIITRTTFALKNCQCAKSIQRKSCDCKCPRDRKYRKCSGKYFINEITVKYQKQKCICHKKKSTVQIVPVCPRFIVVSKGACIAGTFGSYREVIKRQLQQNKQKCHCKVKEVKHKTICGCPSKLINKKLCKSNVFIIEIWAWKINSKKNKCEKYLKSSNRKPIVCKSTKIQKTCNTKTGNGKEVTEKYLLKNCICHKSRSVRKYKCKCNETPVLVKRGRCSGRPKCSRIDYYRQESLRGEKCKRIDSKKIVTCCCPKNKFYDKCEKNNLFKITIDYKLVFDKCVRKEIKKSIKLKCSDRISKITGKCQRNGYKSVAYYRKSLKNCKCIKEKIKSQNCRCRCRKSSSKTICYPRKRSLRTIITNYILAKCKCQPKISETTRTISCPRDSSVSSNCLRKRGTNYWIVSTRTITFSLNGKCKCVSKTVVVNKICRCEINKKVKILCNAKAHETVIRTKFNVLKNGQCIRIVKTASKPVKCDGKWRIKTNSGCKPHGFYGIKTIIYSKLIHNNCNCKEVTKSVSCHCACSGPGFSKVCVNEKIHHKVFYYKIEKCKCRQLTRSERVSPVKCKRVRPKITKCQIIKNRCVRIVEHKDPYTIKCKCFYRTRFEQQPCQTCPCQNFTNRKCNRRSNNIIITTKECRILSNGWIKQNVKTTTQEVPCGVLPKCKQITKCRKKTLTQTFDCLVSYKDNCKCKSRNERKIHPCVCKPVLIQRGKCNRKTCLRSITRTKFHLIVSIYNEKKCVKKSRVYRERCCCPSNAKDVIKCYKNRLTKKIRKYQFDKVKKTCNIIKQNLDITPICKPAVKFVPGKCNKSTCLVTNKYFYKQIISCRCITTKKIAIRECCCRKKDYKEKKCLGRLLVTISHKFVFENSKCSESLKKNSFVVNCKASRIERLKCNPLTRKRKVKYHSFINKKCKCLPKLVVKEILCRCPKPTVRRICLAGKGIVRIINKSYRLNEKLNKCDEIVKNEDQQIKCNNKKRYSCIATKHIHSNGLYKRCTTIWNQRIGCKCIEQLQWIFSLSHCNKAQSSTQCVKNTTVKRKIYYVKQRSSNKKYDYRCVRKEKILPALQILCKKPYIEKSKCIKSFMTYTHHFYIRTSCQCIPRMKIHRVICACGRKKEISRKCVNGRKIRKTFRTYKLNCDNKMIPNCKCMYVDSNVDLRIRCPDDQFKEACIRGKGVRTWTTYDIKNCKCVADKRTNTRTDCKNTICHDILSGKRCRIIKKYGKCKQLNVYSQFLCPITCGYCEKCQPAKIKKYLSQCECKYVAGKKICSRKALITHSVPSGRKCPAKSKVVETFCDCTNELSNKFCLKSLKQGHCNQMKIKQKCAYHCNSHCRQCGKNQLYKSCLQEGKNKGKYEVLRIRFFKLKNSCFFTRKVSYEGRCKLCDTKPYKSVLSCFNGKRFVVTKFVKKLPYGTCKLQEKKEAYSCRGCCEDILTRISSCSNNSRVITIIFWSNVKGHCKRHKVTNVYNCDKKCSNVKFVKTNCVYNKQLVVKTWYSDSVCVPHVVYEVVRC 4019
BLAST of VWFD domain-containing protein vs. Planmine SMEST
Match: SMESG000040791.1 (SMESG000040791.1) HSP 1 Score: 3662.08 bits (9495), Expect = 0.000e+0 Identity = 1953/4018 (48.61%), Postives = 2715/4018 (67.57%), Query Frame = 2
Query: 92 KVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCVLERKSRTIVINCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIKGKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLXXXXXXXXXXXXXXXXXNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLXXXXXXXXXXXXFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSEXXXXXXXXXXXXXXVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMIAKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYECCDXXXXXXXXXXXXRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRTRCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVTKYILINEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVRRRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKTCVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKCPRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVKITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEIKSRIKATFCEISKKRWVKHVICKPPYKTKVCYPKHNRLVIKTYFYVVXXXXXXXXXXXXXXXXXXXXXXXXXRSACGPRGDKGRRYLNVTIKRYRQTRQNKCKLIINRRIEVCECEKTKKMKLCKSGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRCRNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSXXXXXXXXXXXXXXXTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPXXXXXXXXXXXXXXXXXXISTGLCTYVIRKYSVFIRKCKCYRKLIKVIKKERCC--KKPKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGSLFKWIKTGNCGQHKKXXXXXXXXXLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLLKKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEKKHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIGLCYRDRNGFAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTDFYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKCKKGLVLVEEGKCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIRKRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKKSKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXXXXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQKCCCPPNPKDVVKCIHNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKNVSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRCICKPNTVNQICLKDKGIIRKIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTTTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCSCEGPKVVQTQCXXXXXXXXXXXSYKLQCDRKRIPTCRCVFIDTQVDKDVKCPDDKFNEKCVHEAMIRTWTTYDIQNCKCVAESQTDSRPDCKESICKDVLTNNKCHKIKKFGKCNQMNIYYQFLCPLTCGYCEKCDKPAIKKYLSECSCKMIAGKRICSRSVLVIEFIPDGKKCRKVKRIVESLCDCSNILPNSVCEKSMRDGRCGNPRIRAKCAYHCNPKCQHCERNRVYKICLQSGPNKGKYEILRIKYFKIEGACFFIRKISYEGSCELCSKRRTKIVTSCFEGKRFVITKYVVKRRDGTCKNMERRVAYSCTDCCNEIITKIGVCGSRSRVVIITFWANIKGCCRKQKVVNKYACNNRCARIESVQSRCMYNKQLVIKTWYSDKMCLPHTVYELADC 12139
K+ K PC NG R + Y++ C P +KT +C K+K FCKCSA+GDP+Y+TYDGQV HFYG CRYT +++ DPCSFNIEVQN Y+ D+K F YTKSVIIHMF ++YELGQ LKVN +R+PYEK V+I +SR LQFVAP+C +RV FDGD+NA+V+VS RYS +MNG+CG+CNG DD KTK G DVS ++NKYSL+GNSY+VS G C AK++SY +C K+W++ KAKK CG L+E ++PF +C KG++ L+ F+++C+ID+C +P RWQK RCE+FSGLA+VCS+ G + WR CPL+CGKN+H S A CP TCEN+FFGTK PCY+ +EGC CN+GYIRDG+LCVKP HC+CI++CVDRE SE C+ WK +G CK+ S+AM IICPKTCGFC+ CED L ++CL+FR +GLC FYKA+CGLTCNYDKC CGK++ VGKC+ NRI TTH KF RD +G CAK++ +++ CNC KVTK CN CTG R + ++++ I NKCV +K+++ EKC KC + R +CI NR IK T F +L GC+ CV ++K T I CK+++ K D+ TC+++ K+I RRP+NC+C E V NR+ WCCNKKPK L P C+ G+IIHRTI+Y F +GC P KD IEIPKCK ++ KGKC R G FCKA D + K+N+ CKC+ KL RTCCC+K + TTCN +GI T V + L+KK ++ C+R K+ S TI+ KT+++ IKGKC +NCLRK+ I++KFR GC V +F + + R+CCC PKQ + I CI + IV KV++R K+N C +V+ + KK + CP VKE+KC++RR ++++T I Y ++KC+C +R + ++C C YK TK G C+K TC R Y FQN+ C+ K CCC R IK SYC+R RY ++K+WEFN KLR+CI ++ + A P C + +KG CG +KN+ K+IT E S CKC+K VTW C CP+ K K+ C G +I E + L K +KC+ +R V+CP + + K ++KC+YK YTG MKP NC+C W Y+CC + + K + I+TK + + ++ CI V R ++AITC +Y+ + +T+CK G+YW+ T Y V NCKC + R T KVIC+CIP T+KR C GAG + I TK+ LIN KCI +K F P +C + D KC+RKTG+ITV R+Y + CKCVR K T +VRCPCFRKDR+V+++C +R +E+QR K KCIWK IKS+ EDC+C R T C +H +R+ Y L+ T+ IPLQ+C K +K + ++CNR Y K C+ H+ IE +CIYEK NCRCVK C+ + GPC+C+RLNKC +KC+ N ++++C +K GR C KS+ I EKC KI+CKSCS+++NNG+++ C T++ Y NC+CV+K + +LCKC D +RP C+ NRK I+T SFY +KNHCV RKRQ F+ I+C P ++ KCST Y L Y+ ++ CKCVK I + NSKCC KP K C K HW T F Q+PT +KLFP IKS + ATFC+ KK W K + C Y C+ K +RL IK ++Y V CKC+LKV+ K + C CPK K+IRS CGP GRRY ++TI+ +R+ + NKC I +R EVC CEK+K + C G+R+F TIWYNI TKP CKP++ K++ISI C+N GRKNKWI + V CR G +T+K+FER +N K C+CK++ KS K+ ICCKP F CRNN EHI I + + LKC S K + C KP EVVGNC+GKVIRYR ++R V C+CV+ V YR +K D +CV++ +W+ + IPYKLI+G+C +I C L++FVD++I+ CTFKR +IGK K+C C D V +T+ILNY+CC+K++V +C ++ KV T SYRL+ FKC+PV K+ K ++C L+ ER STG CTY I YSVFIR CKCYRKL KVIKK CC KKP CD+ G KI + S+ H KDD C+K + S INC R+ C+K E +C+K T+ + ++C RK CKC++ KVKE + CCG F WIK+ +C Q+++ +IR RYY LK K C+AV+VKE + RC+CP + M CV + ++R Y+LK +C L S+K++ + CP+K K+++ C++KTGW+ +VYRI YPK+CKC++K + KEICICS+AFP+ KE+ CK +V++KR+A CT+ +VKW+IIT + I+HCKK K EIG CY+ + G A+SIRYD VQYF K CRCQRKV+KRILKHC C+ H S +C+ N + +SY + +G C +++ ++ KVPC KP I+K C +NKYI+T+ T++ KNC+C SI+RK+CDCKC ++RKYRKCS Y I E+++ Y K+ C C ++KS Q VP CPRFIV +KG C+ G YRE+I+R+L ++ + C C VKEVK K IC C + +K C SN ++E+W WK+N ++N+CE+YL SSN P C I+ CN KTG K++ YL++ C C K V+K +CKC + VLV+ G+C+ RP C RID YR E L KC + + V CCC K + Y +CE +N+ + I + L KCV+ EI+ S LKCS +++ KC +NG+K Y+++ L+NCKC+K + C+CRC+++ + IC RKR ++TI + L KCKC K S +I CP + S S C+R R TNYW+ +TRT + +N +C CV + +KICRC+ N+K K++C+AK H + TKF VL+NGQC+R+ T + ++C+GKWR+K+ SGC+P GFYG+KT+ YSKL+H+ C CKE++K+ CHCACSG S VCV E+IH K++ YKI KCKCRQL RSE VS VKC+++RPKI KC+I++NRCV++V H+ PYTI C+C YR + PC+TC C +T +KC SN +I C IL NG I+++V+ +E+ C + C+Q+TKC KK++TQ F C V +K NCKC+S+ ++ +PC CKP ++ GKCNRKTCL+++TR FHL+V N+ KC ++ R Y+++CCCP N KDV+KC NR +K ++ FDK +KTC+II+++ D TP+C+P V+ + GKC+K CL +++++C+C + + +R+CCC +KD+ + KC+ + V ++FVF+N KC + + + + ++ C+ S + R KCN T R ++ H + +KC+C+ + VKE+ C C TV +ICL KGI+R I SY+LNE+ N+CD+ ++NED+QI CN ++ C T NG +++CTT W +R+GCKC EQ+ WIFSL HC K ++ +C++N V KIYYVK+RS K YDY+CV+K K++ + + LC + Y + CI SF TYT+H++ R CQC+P K++RV C+C K + +C++ +IR T R+YKL CD K IP C+C+++D+ VD ++CPDD+F E C+ +RTWTTYDI+NCKCVA+ +T++R DCK +IC D+L+ +C IKK+GKC Q+N+Y QFLCP+TCGYCEKC IKKYLS+C CK +AGK+ICSR L+ +P G+KC ++VE+ CDC+N L N C KS++ G C +I+ KCAYHCN C+ C +N++YK CLQ G NKGKYE+LRI++FK++ +CFF RK+SYEG C+LC + K V SCF GKRFV+TK+V K GTCK E++ AYSC CC +I+T+I C + SRV+ I FW+N+KG C++ KV N Y C+ +C+ ++ V++ C+YNKQLV+KTWYSD +C+PH VYE+ C
Sbjct: 4 KIIKGPCENGIRIVTTIKYLEVLRKCKPIESKTTESCGRKKKRFCKCSALGDPYYKTYDGQVFHFYGSCRYTFSKYKSVQDPCSFNIEVQNGYKSDDKTFPYTKSVIIHMFGQIYELGQGKTLKVNDNPTRIPYEKDKKVKISQSRDILQFVAPKCLIRVGFDGDANAYVQVSTRYSGQMNGLCGNCNGKHDDLKTKDGTDVSRRKNKYSLVGNSYNVSTTGKACAPAKEVSYEDLCDKNWLQYFKAKKFCGGLIEEDSPFKECENKGHIVLKQFYENCLIDLCSKTKKPKRWQKARCELFSGLADVCSDNGVAVLDWRKILVCPLKCGKNSHLSVNAKLCPETCENYFFGTKNPCYESSSKEGCNCNKGYIRDGSLCVKPTHCRCISICVDREKSENCKDWKSKGHCKQFSKAMKIICPKTCGFCQVKDETCEDYLRFKRCLKFRRQGLCTSAFYKAVCGLTCNYDKCGCGKKKTIVGKCNKHKNRIKTTHIKFVRDPRGICAKVVGYTYQVCNCKKVTKKVGSCNFCTGKRIVTMNVETINGNKCVTQKKIVFEKCKKCDLKSRFTEKCIANRVIKKTTIFNRLSGCFRCVKDQKFETREIKCKNSRIEKLDKRTCLKHIKVITRRPLNCKCVESVTNRKVVWCCNKKPKVLKPFCRKGKIIHRTIFYVFRNHGCQPAPKDKIEIPKCKQNKEKNKGKCHRLLKGVHFCKATDVTRISKVNNACKCVVEKLHHTRTCCCKKPRNYTTCNRLLGILTAVKVEHSLIKKADKFECLRKAKQTSTTIKQKTEYLEIKGKCHSNCLRKNKIVKKFRDGCTVKVQFVKFQTRICCCLPKQIRTIECIADCIVTKVFRREFKSNSCRKVLISNVKKSVVCPKPTVKETKCIFRRNKKRVTKIFYVVQKCRCVRRKLVKIEKCKDCLYKETKTKEGPCNKKTCQRVIYTNFQNKYCENSVKKSHSTCCCRQRPIKSSYCDRFTSYRYHVVKFWEFNPKLRSCISKTTKKAHRPICNKDKVIKGGCGTIKKNFRKLITIREIVSPLDCKCKKTEIVTWNRCSCPVGKTTKR-CVGETLEIIEVGFKLTKDESKCVANKSVKRQSVICPRVVRRHTKVLSKCSYKSYTGYMKPKNCKCTLHWNKVVLYKCCQKPKISSKCFKN-KTIITKITKFIVSKDKKKCIPSVIRKTVAITCPRYVNVEKTKCKKGIYWVTTTKYAVVNCKCVQTRKTGTKVICKCIPGHTIKRHCTGAGIKTITTKFTLINGKCIPAAKTEFNPTRCGGAVDKPGKCNRKTGMITVNRMYFEAVKCKCVRRKSTHSVRCPCFRKDRVVKKQCIN-MKRIVEVQRHKLHKSKCIWKTIKSFSEDCKCSRNSFKTECFKHAAFRSNFVNYQLRTVSTYQIPLQRCFKSNSQKTKPLLCNRDYSEKRCINHQLIETKCIYEKINCRCVKNCRMIKIGPCQCRRLNKCLQKCVNNRKFSICLTYKPGRISCEKSQKQTLIPEKCLPTKIQCKSCSVKRNNGIFKICIKTFYEYQNCECVKKQKPIHKLCKCDRDRNNRPYCLANRKAIDTISFYPIKNHCVERKRQTFLKIDCPAPVIKTDNGKCSTKYTLIYYEVKKCKCVKKVIEKTNSKCCRKPTINKMCSKDHWTFTQIHFQQKPTTLKLFPTIKSSVLATFCQTVKKNWRKRISCPKSYTITTCHVKTDRLEIKHFYYAVNGCKCELKVTTKFETCRPCPKKKVIRSKCGPIALMGRRYFDLTIRGWRKQKNNKCTSYIKKRKEVCLCEKSKNYEQCLQGKRVFTTIWYNIKTKPACKPSIEKRSISIPCYNNGRKNKWIPTKVVTCRRHGHFTVKHFERLEFNPKACTCKKVYKSTKIGICCKPCHFKTVCRNNNYEHISICQESKNLKCVKKLSKKIRTVTCEKPLKEVVGNCNGKVIRYRITTFRKVNCKCVKSVTYRNKIKPIDRRECVKN-TWKITRIPYKLIHGVCQRGKPQIISDSTVCIMLIKFVDRKINSCTFKRLYIGKTVKNCVCVDKVIRTEILNYKCCKKNIVKLSCMKDRVKVVTTTSYRLMGFKCYPVIKIAKADIKCHLKTEERKSTGKCTYKILNYSVFIRNCKCYRKLGKVIKKAHCCSHKKPFTKRLCDSLKGFKIIIQTSFHHKKDDTCVKFDKKTSIPINCKRLACSKIEGQCVKKTRNIQVFCFKRKGCKCVKVKVKELQTCCGKRFNWIKSDSCSQNRRDFIRTRYYALKFVPKTKLCQAVVVKETYKRCRCPSIASSMRCVKDNSYLIVRTSYVLKGNSCNLITSKKIIPVKKCPKKIITKIKETCNRKTGWKTIVYRITYPKNCKCLQKTFTKKEICICSIAFPNPKEKTSCKNHYIVVKEKRLASCTKTKVKWSIITNQLPILHCKKTKTEIGRCYKSKTGNAVSIRYDVVVQYFMKNCRCQRKVLKRILKHCTCKRTHSSIKCIGNKKIETTFSYVLVKGFCIKKINRNTIKVPCSLKPKISKFPCVKNKYIITRTTFALKNCQCAKSIQRKSCDCKCPRDRKYRKCSGKYFINEITVKYQKQKCICHKKKSTVQIVPVCPRFIVVSKGACIAGTFGSYREVIKRQLQQNKQKCHCKVKEVKHKTICGCPSKLINKKLCKSNVFIIEIWAWKINSKKNKCEKYLKSSNRKPIVCKSTKIQKTCNTKTGNGKEVTEKYLLKNCICHKSRSVRKYKCKCNETPVLVKRGRCSGRPKCSRIDYYRQESLRGEKCKRIDSKKIVTCCCPKNKFYDKCEKNNLFKITIDYKLVFDKCVRKEIKKSIKLKCSDRISKITGKCQRNGYKSVAYYRKSLKNCKCIKEKIKSQNCRCRCRKSSSKTICYPRKRSLRTIITNYILAKCKCQPKISETTRTISCPRDSSVSSNCLRKRGTNYWIVSTRTITFSLNGKCKCVSKTVVVNKICRCEINKKVKILCNAKAHETVIRTKFNVLKNGQCIRIVKTASKPVKCDGKWRIKTNSGCKPHGFYGIKTIIYSKLIHNNCNCKEVTKSVSCHCACSGPGFSKVCVNEKIHHKVFYYKIEKCKCRQLTRSERVSPVKCKRVRPKITKCQIIKNRCVRIVEHKDPYTIKCKCFYRTRFEQQPCQTCPCQNFTNRKCNRRSNNIIITTKECRILSNGWIKQNVKTTTQEVPCGVLPKCKQITKCRKKTLTQTFDCLVSYKDNCKCKSRNERKIHPCVCKPVLIQRGKCNRKTCLRSITRTKFHLIVSIYNEKKCVKKSRVYRERCCCPSNAKDVIKCYKNRLTKKIRKYQFDKVKKTCNIIKQNLDITPICKPAVKFVPGKCNKSTCLVTNKYFYKQIISCRCITTKKIAIRECCCRKKDYKEKKCLGRLLVTISHKFVFENSKCSESLKKNSFVVNCKASRIERLKCNPLTRKRKVKYHSFINKKCKCLPKLVVKEILCRCPKPTVRRICLAGKGIVRIINKSYRLNEKLNKCDEIVKNEDQQIKCNNKKRYSCIATKHIHSNGLYKRCTTIWNQRIGCKCIEQLQWIFSLSHCNKAQSSTQCVKNTTVKRKIYYVKQRSSNKKYDYRCVRKEKILPALQILCKKPYIEKSKCIKSFMTYTHHFYIRTSCQCIPRMKIHRVICACGRKKEISRKCVNGRKIRKTFRTYKLNCDNKMIPNCKCMYVDSNVDLRIRCPDDQFKEACIRGKGVRTWTTYDIKNCKCVADKRTNTRTDCKNTICHDILSGKRCRIIKKYGKCKQLNVYSQFLCPITCGYCEKCQPAKIKKYLSQCECKYVAGKKICSRKALITHSVPSGRKCPAKSKVVETFCDCTNELSNKFCLKSLKQGHCNQMKIKQKCAYHCNSHCRQCGKNQLYKSCLQEGKNKGKYEVLRIRFFKLKNSCFFTRKVSYEGRCKLCDTKPYKSVLSCFNGKRFVVTKFVKKLPYGTCKLQEKKEAYSCRGCCEDILTRISSCSNNSRVITIIFWSNVKGHCKRHKVTNVYNCDKKCSNVKFVKTNCVYNKQLVVKTWYSDSVCVPHVVYEVVRC 4017
BLAST of VWFD domain-containing protein vs. Planmine SMEST
Match: SMESG000040790.1 (SMESG000040790.1) HSP 1 Score: 1839.31 bits (4763), Expect = 0.000e+0 Identity = 1302/3697 (35.22%), Postives = 1971/3697 (53.31%), Query Frame = 2
Query: 62 ATRYGVCQNTKVEKEPCTNGTRNIRITTYVKDNGVCTPFRTKTQVNCESKRKDFCKCSAVGDPHYRTYDGQVIHFYGDCRYTLTQHNREDDPCSFNIEVQNEYRGDNKYFTYTKSVIIHMFREVYELGQKGVLKVNGQLSRVPYEKSDDVRIFKSRKFLQFVAPRCSVRVAFDGDSNAFVEVSKRYSKKMNGICGDCNGVRDDFKTKSGRDVSNKRNKYSLIGNSYHVSKPGHHCKKAKDISYHSICGKDWIRSLKAKKHCGVLLEPNNPFSKCARKGNVDLRNFFQDCVIDMCVNKNRPSRWQKVRCEIFSGLAEVCSEAGFEGIKWRSQFNCPLQCGKNAHFSEKANPCPRTCENHFFGTKRPCYDLPEREGCACNRGYIRDGALCVKPMHCKCINLCVDRESSEKCRKWKQQGQCKELSEAMNIICPKTCGFCKATAGHCEDELSARKCLEFRNKGLCYHDFYKAICGLTCNYDKCNCGKERIFVGKCDMSTNRITTTHYKFARDSQGRCAKIITQSHKACNCNKVTKVRKRCNLCTGIRKIILHIKEIVANKCVRRKRVIVEKCNKCHKRIRKQRRCIGNRSIKTTITFYKLKGCYLCVLERKSRTIVINCKSTKTVKRDRLTCVEYTKIIRRRPVNCRCREDVINRRRKWCCNKKPKHLPPKCQNGRIIHRTIYYKFHRNGCVPHFKDVIEIPKCKPERKSIK-GKCVRKRHGRFFCKAIDFKLVRKLNSKCKCITRKLXXXXXXXXXXXXXXXXXNWRMGIQTVVTTRYRLVKKRHRYVCVRFEKRVSKTIRFKTQFIVIKGKCGANCLRKDTIIRKFRYGCKVIKRFSRHEVRLCCCRPKQRKFICCIGNDIVVKVYKRILKANRCVRVVKTCHKKRIRCPPKVVKESKCVYRRRRRKITTISYFLKKCKCFKRTRICYKRCPGCQYKVLXXXXXXXXXXXXFRRTYIFFQNEKCQKGTKICDYRCCCPFRKIKRSYCNRCNGIRYDILKWWEFNEKLRTCIPRSKRIAFVPKCKRGIKVKGKCGVERKNYIKIITTSEXXXXXXXXXXXXXXVTWKVCKCPLRKVVKKTCRGTFYQIKEYEYHLDKIRNKCLRRTIRRRDGVLCPMI-AKTKRKNITKCTYKIYTGIMKPTNCRCKWVWRAEKFYECCDXXXXXXXXXXXXRFIVTKSITYQLISRRRPCIRRVKRSSIAITCKKYIRIRRT-RCKNGLYWIITNFYQVNNCKCGKVRTTRRKVICECIPSETVKRICIGAGHQKIVT-KYILI-NEKCIAHSKVTFYPKKCPPSYDVRSKCDRKTGLITVRRIYHVSKNCKCVREKLTLTVRCPCFRKDRIVR-RRCDKKGRRTIEIQRRVSSKRKCIWKVIKSYWEDCRCPRPRSITRCVEHGIYRTKTTFYLLKVTFTHAIPLQKCVKFEREKDRKIICNRGYVTKT-CVRHRKIEVRCIYEKRNCRCVKYCKTVITGPCKCKRLNKCSEKCIKNVRYNVCYRFKAGRKHCIKSRHDYPIREKC-PRRKIECKSCSLRKNNGVYRSCRITYFVYHNCKCVEKHRYRLRLCKCGGDITSRPRCVNNRKVIETTSFYRVKNHCVGRKRQHFILINCFRPRLRITELKCSTSYKLEYFYLRNCKCVK-ITIIRKNSKCCIKPIFTKKCKKHHWVLTIKSFHQRPTNIKLFPEIKSRIKATFCEISKKRWVKHVICKPPYKTKVCYPKHN-RLVIKTYFYVVXXXXXXXXXXXXXXXXXXXXXXXXXRSACGPRGDKGRRYLNVTIKRYRQTRQNKCKLIINRRIEVCECEKTKKMKLCKSGQRIFITIWYNIATKPVCKPTLIKKAISISCFNKGRKNKWILVRTVRCRYPGEYTIKYFERDVYNSKTCSCKRIKKSRKVSICCKPTKFIKRC-RNNAIEHIRISEVPRALKCNIVSSTKRFPIICRKPRTEVVGNCHGKVIRYRTVSXXXXXXXXXXXXXXXTIMKRSDSIKCVRHMSWRRSHIPYKLINGLCVAQPARITYRYIGCSKLVRFVDKRIDECTFKRSFIGKYPKHCKCTDFVKKTKILNYRCCQKSVVMKTCEHNKTKVTTRISYRLLDFKCFPXXXXXXXXX-XXXXXXXXXISTGLCTYVIRKYSVFIRKCKCYRKLIKVIKKE-RCCKK--PKVSYRCDAKTGKKIFVTISYQHTKDDVCIKLRRVVSNLINCHRIKCTKTESRCIKNTKTVYMYCHLRKACKCIRTKVKEFRHCCGS--LFKWIKTGNCG--QHKKXXXXXXXXXLKMDKAGKRCRAVLVKEQFVRCKCPKSFTKMTCVLNRYNKVIRYYYLL--KKGTCFLKKSQKLVLISSCPEKTKIKVRDHCSKKTGWRYVVYRIIYPKHCKCVEK-KHSFKEICICSVAFPSSKERIYCKKDNTIVRDKRVAICTRKRVKWTIITISIKIVHCKKVKIEIG------------------------------LCYRDRNG--------FAISIRYDTKVQYFTKKCRCQRKVIKRILKHCACRANHRSKQCVANSIVIKNYSYSIKRGRCQQRVRKSVRKVPCPNKPSITKSKCRRNKYIVTKRTYSRKNCRCLVSIRRKTXXXXXXXXXXXXXXXXNYAILEVSIVYHKKHCRCVRRKSIQQFVPSCPRFIVKTKGPCVPGKTD--FYREIIRRKLVKDFKNCKCLVKEVKRKRICACRKTIEKRKRCVSNHKVVEVWGWKVNRRRNRCERYLVSSNSVPKRCPKRTIRIICNPKTGVEKKIITTYLIRQCKCLKRIRVKKSRCKC-KKGLVLVEEG---KCAKRPVCVRIDKYRYEILVKGKCIKKLKEVKVICCCAKKQKYKRCEGHNMVTVIISFTLKLGKCVKSEIRTSAHLKCSSKVTVKESKCGKNGFKIRRYFKEKLRNCKCVKRMVDEDRCQCRCQRNFKRKICNIR-KRFIKTITVTFHLKKCKCIRKKSTEILSIKCPSEHSSVSLCIRIRKTNYWLKTTRTTRYFVNNRCVCVPRVYKK-SKICRCKRNRKTKVICSAKKHALIYVTKFTVLRNGQCVRVANTRIQRIRCNGKWRLKSESGCQPRGFYGVKTLTYSKLVHDKCRCKEISKTKRCHCACSGIPSSTVCVKERIHRXXXXXXXXXXXXRQLIRSENVSFVKCRKIRPKIGKCKIVRNRCVKVVVHRIPYTINCRCHYRRKLVYVPCKTCRCPQYTTKKCQASSNRFVIKRHICHILGNGLIQKSVEVKMKEIHCVSIMTCRQVTKCHKKSMTQKFLCRVPHKTNCKCRSKEVKRTYPCKCKPDEMKIGKCNRKTCLKTLTRKIFHLVVLTNNKVKCQEEKRFYKQK-CCCPPNPKDVVKCIHNRKIRKTVRFVFDKSQKTCSIIRRSFDETPLCQPPVRKIKGKCDKKRCLKRITSIKRRLVNCQCRKRRDVKLRKCCCLRKDHIKVKCIKN--VSVVSKYRFVFKNGKCHKFVNRINHIIKCRRSHVHRGKCNLRTGFRVLRIHKYRKEKCRCIRSVKVKELRC-ICKPNTVNQICLKDKGIIRKIFTSYKLNERRNRCDKFIRNEDRQISCNKNEKTECSPTTRREKNGAFRKCTTTWKERVGCKCEEQIHWIFSLLHCKKPTTTRKCIENNIVSTKIYYVKERSLVKNYDYKCVKKRKVIVSPRKLCTRSYTTTTDCIDSFKTYTYHYHKRIMCQCVPMTKVYRVKCS 10936
++ VC+ V+KEPC NG R + IT ++K+NGVC PF +KT + C +RKDFCKCSAVG HYRTYDGQ IHFYGDCRYTL+ +N D CSFNIEVQN + G +Y +S+IIHMF E YELG + LK+ +PYEK DVRIF S F+QFVAP+CSVRVAF+G SNAF+ V+++YS KM+GICG+CNG DD +TKSG+DVS +N+++ I NSY V+ G +C A ISY +ICG + R K C +L NPF KC ++ VDL++F+ DC++ +C+NKNRP + ++V+C+I GLAE CSE+G GI WRS F C +CGKN HFS+K +PCPRTCENHF+GT+RPCYDLPEREGC CN+G+IRDGALCVKP+HCKC++LC DR++S+ CRKWKQ+G C++ E MN++CP+TCGFCK CE+E+S ++CL FR KGLC+H+FY++ICGLTCN++KC CG + VG CD +TN ITT H + RDS+GRC K++ ++KAC+C K RCN CTG R + E+V KCV R + E C +C + R++ RC ++ + +TF +++GCY CV +++ + + CKST V+R C +Y NCRC+ + + K CC + K + C+N IH T + K + C P K P C P R +IK +CVR R G F CKA D + + + CKC + + R CCCR+S + CN + GI T +T + LV Y CVR E I+F T++ KG C ANC R D I + FR GCK+ F + R CCC P++ C+ V +KRILK NRC+ V + + + CP SKCV R + IT SY++ KC+C ++ I P C++KV+ + C+ TC Q E C+ TK+C +CCCP + + S+CN G K +++N+K C ++ KC + +K +CG ER NY KI E K+ C C++ V WK CK P V K CRG ++ ++ Y K + KC+R RR V CP I + + K I+KC +K +T + NC C E + CC +K T K+F V ++++Y+L S ++ C++ + ++ I C + R R+T R + Y IIT++++V NCKC K+RT +K + C+ +T K CI + T + L+ NEKC+ KC Y V C + T L +++R ++ NCKC +K + C C + VR +C+ G RT + + V C W + SY + CRC + S T C+ H ++RT T L+ A P +CVK + D ++C R Y T C+ HRK +V+C Y K NC+C C+ V PC CK L+KC +CIKNV+Y+ C R++A C+ ++ P+ E C RK +C + N+ +Y C + +Y +C+CV+ + KC + CVNN++ I TTSF N CV R+ Q I C R R R T +++ Y+ NCKC+K I + K C K+C ++ WV T + + T+ +L PEI + +K C + K + VIC+ +K C + +LV K F V + + + + C CP + +ACG G Y+ V K + ++ KC L + ++ C K + +C++GQR F T Y + +K C+P + AI I C+NKG+ N W V+T CRYPGEYTIK+FER +N C C+R KKS K ICC ++ + C R+ + +I IS P LKC + + C + V+G+C G +IRYR +++ CRC+++V+ + K +D ++CV +M W+R+HI Y+LI CVA+ IT+R I CS + D RI+ C F RS+ +C+C + + L+Y+CC+K + ++ C +K + Y L++F+C PV++VTK + C + RI TG CT+ + KY V + CKC R L K I+ RC PK RC+A+TG+ + + SY+ + I + +V + +NC KC SRCI NT+T+ C R+ C+C++ + + CCG W +TG CG + K +Y + + LK++ K C+ VL+ Q C+ P FT +C+ + K I Y L + C K + + L+ C + KIK+ S + G+ Y+IIYP++CKC +K K + C C P+ + YC K+ V + R IC + W I +I +C +I G YR R G + RY+T +Q+F C CQ K + + C +H ++C+ + +I YSYSI +G CQ+ + + +PC P + KS C NKY +T +Y +NC+C+ ++K C CKC N++ +CSRNY + +++ Y K++CRC++ ++I+Q +P CP+++ +T G C P K++ YR++ R L K +C+C V E + +IC C++ EK+K C++N+ V + W +N R+N+CE L S++ CPK C K + K + T Y ++ C+C++ V+K +C C KK VLV+ G C+K +R D Y+ ++ KCI +++ K ICCC +K + C + V + ++ L+ C K I+ + ++C + + V+ S+C GFKI + +RNCKC +V + C+C+C+ + + C+ K++I+T + L C+CI+ K+ + IKCPS H+ VS C + +K N ++K T Y + +C R ++K SKI CK +V C KK + TV R +CV + + + I+C+ KWRL + C G +G + Y KLV C C I+KT+ C C C+G C + I + Y+YK+ KCKC ++++ + C K C + VK V R NC+C V PCK K+C+ ++N++VI C + G I VK + C + C ++CH + QK C NC C++K +T PC C P ++ GKCN KTCL+ + R LV + N K KC EK K + CCC C N I+ + F+ +K C + + TP C P + +G CD+K C +RI I+ L +C+C + V+++ CCC + + KC+ N V+ Y KC+ V + I C N G V + Y + CRC +V +C C+P C + KGI++ ++ +E C + + ++++I C + + + + ++K G + TTT + R+ CKCE + L C++ KC+ N + +I Y++ ++ NYDY CVKK + + +C R+ + T + K+ TY K C+CVP + + C+
Sbjct: 1 MSQESVCRKASVKKEPCINGKRYVTITNFIKENGVCRPFTSKTNLYCGLERKDFCKCSAVGGLHYRTYDGQGIHFYGDCRYTLSNYNSGRDSCSFNIEVQNHFGGKQSVNSYARSIIIHMFGEKYELGPRRSLKIGNVKRSIPYEKDRDVRIFYSNDFVQFVAPKCSVRVAFNGKSNAFISVARKYSGKMSGICGNCNGRHDDLRTKSGKDVSKSKNRFARIANSYKVTNFGKNCLPAAQISYKNICGSHFYRQNKHSI-CQDILINKNPFKKCGKQAFVDLKSFYDDCLLVLCINKNRPHKIKRVQCQILEGLAEACSESGVPGIGWRSLFKCQKKCGKNQHFSQKVSPCPRTCENHFYGTQRPCYDLPEREGCECNKGFIRDGALCVKPVHCKCMSLCTDRKNSKSCRKWKQRGDCEKFQEPMNVLCPRTCGFCKIRNIACENEISTKRCLAFRRKGLCFHEFYRSICGLTCNFEKCKCGNDETIVGTCDKTTNIITTFHNSYTRDSKGRCVKLVRHTYKACDCPKDWVQTGRCNFCTGKRNVTSFYYEVVKYKCVLRSFIRYETCKRCLENARERLRCDNDKYLTKIVTFQRVQGCYDCVSDKRISSTEVKCKSTLIVRRK--GCDKYITKTMGLARNCRCQVSIRRWQEKECCLFRKKTI--HCKNKEFIHTTYFEKLIKAKCYPKTKYRFVTPAC-PVRNTIKRAECVRNRKGVFHCKADDIQEISGITKNCKCFRKFIRRPRICCCRESYKYQKCNRKFGILTTITVTFELVNSCGNYRCVRKEFSFCTRIKFTTKYTRRKGICQANCKRTDQIWKTFRDGCKIKTEFHEYSARTCCCHPERVIKKKCVFKTKVFTEFKRILKNNRCLDVQISRKETPVLCPAATEVTSKCV--RNAKTITKTSYYVHKCEC-RKLEISTVISPCCKFKVISERVLSCNLQTCLTSHITVSQGEDCEYRTKVCPVKCCCP-KPQRNSFCNPNTGQIVTSTKTFQYNKKCFKCSSKTSVKFSCIKCNKARVIKHRCGQERNNYRKITIIKEHLYKNSCSCKRTERVIWKCCKLPKSSTVTK-CRGNYFDVEITSYKFGKNKQKCIREINRRVHPVQCPPIKPQYETKPISKCKFKQFTYYYQIENCHCVKKSSHEILFSCCPKKRLITKCNAHKQF-VYRTLSYRLTSDKKKCLKYLATTTQLIQCGSHSRSRKTERKPDCTYAIITDYFKVRNCKCQKIRTKTQKKLWCCLKPKT-KFSCIANKTWRTTTIAFTLVNNEKCVKKKTNVDRVIKCQDPYSVVCPCGKWTNLKSIKRYFYNVVNCKC--KKRMIHFPCICHKVPNKVRYGKCNANGMRTARVFKSVLVGEHCKWHLFTSYQDCCRCSKNLSKTVCLAHSVWRT-TKISCLRRQAPGAYPHHQCVKSKMVYDIPVVCYRDYSYVTPCINHRKRKVQCSYRKVNCKCELSCRQVAVRPCPCKTLDKCRTQCIKNVKYSKCKRYRAEGMRCVLTKTALPLVEHCSSERKTKCTLGKVYINHCLYTLCFTKFSIYQDCRCVKDTKAISTCSKCRNPFVT-VSCVNNKQFITTTSFIPKNNKCVRRRSQTSKNIECPRWRARTTRRHGYYYHRITYYKNINCKCIKRICQEKYFRKQCPISKTKKQCIRNQWVYTFVNRQIQFTHRRLCPEIDTGMKEKICVENIKMKFQPVICRRDFKIIKCDVRRKLKLVEKHIFRPVNCQCKESTIIQTSRSCKNCPLPIVRETACGKINKNGIGYIFVYSKFWGINKEKKCVLKHEKTKKIGCCRKPHNIIVCENGQRKFKTFHYEVISK--CRPRVTVTAIPIHCYNKGQPNYWKHVKTTFCRYPGEYTIKHFERLKFNPVQCICQRQKKSVKTDICCGKDQYSRECRRDKNLVYITISHRPTNLKCVTHRRERIKNVSCPRDHRMVIGDCQGLLIRYRKTTFQTKNCRCLKKVKVYSRQKIADRVECVSNM-WQRTHIGYQLIRDRCVAKRPFITFRRITCSMAETYKDSRINNCDFWRSYYVNVVSNCRCVKKFVRKENLHYKCCKKPLEIRRCIRDKITAIYKTRYHLVNFRCHPVRRVTKIPVCCCHIPTVSRIFTGKCTFNLLKYLVIPKNCKCVRILKKTIRNLCRCADHLTPKTEQRCEAETGRHLTINTSYRCVNHKI-ITVTKVTAIPVNCDGRKCKNIYSRCIHNTQTIQQLCLRRQGCRCVKKLINQRNVCCGPRKDSTWTETGPCGIVKQKCHYRFVKTFALKLNVRTKICQPVLINHQHSICRIPNPFTVRSCLNHISIKKILVSYKLNVQNNVCDEIKKESVSLVPGCHKTIKIKLSVKVSNREGYCDAKYKIIYPRNCKCHQKIKFIRYKHCSCYKRQPTVQVNRYCLKNVIKVVETRSPICIISTINWVITKKFYRIRNCSHKQIIYGHRFRCGTSNYGGRHGSSGFTHRFFFHRSSTHSYRHRLGGRNSGRMRYCEQSRYETHLQWFVGNCVCQSKTLWQGPMCIRCLPSHEEERCMVSKKLITRYSYSIVKGTCQRSISRRTIHIPCSRSPRVVKSSCHNNKYTLTNISYFYRNCQCMSQAKKKVCHCKCPSNKQTIRCSRNYFLNKITTKYRKQNCRCIKSETIKQILPICPQYVPQTIGNC-PRKSNEHSYRKVTTRHLRKHESSCRCSVAEDVKLKICRCKEREEKQKLCINNNFVHQTLKWIINERKNKCELRLSKSHTEFVTCPKSFSSRSC--KKDIVKIVTTFYKLKNCRCIEHQNVEKFKCSCNKKASVLVKTGHCPSCSKFRDSIRFDTYKRSLVRGNKCIGIMEKRKEICCCRLPRKVRFCRLDHFVNLHFTYKLEGQTCRKERIKRNDFVRCQNGIRVEHSECRPRGFKIIYSIGQVVRNCKCHDHVVKQRYCKCKCRDSKVVRKCDCSGKQYIET-HYRYELSNCQCIKMKTKRFIPIKCPSSHTEVSKCKKGKKANEYVKIITETFYVIE---LCKCRQHQKRSKIICCKIEESKEVFCDTKKQVEVRRHFRTVFRYDKCVHLRDEKRVPIKCDEKWRLVNNPICHSDGQFGKENRIYQKLVFKNCGCSVITKTRICDCKCTGPSVIDRCGGDFILKHYYEYKLHKCKCMRILKKIERKPIHCDDKPSKKSPCIFNHGKYVKYVEKRRGVVSNCKCSINPITVIKPCKVECGDPIVKKRCKRATNQWVITTERCEVSECGCISYYNHVKTSLVFCEAKEECTPRSECHPVTNIQKIDCETTFLENCLCQTKREPKTGPCVCGPSSIQYGKCNVKTCLQEVFRVENKLVSIKNGKTKCHPEKTQIKDRVCCCVKKSATTETCTKNILIQTIKTYTFNDQEKQCEESTKINNRTPECGPEIETKRGLCDRKTCKRRIREIRSSLTDCKCNVKESVQVKLCCCDPEVKSEEKCVGNQLVTFFYTYSLSKDEEKCYVKVTKNAKEIPCPEDSTATSYIN---GHTVCQKTSYTLKNCRCEPTVTNVGCKCDDCRPRPETSYCDEAKGILQTTKSTANFDE-SGYCVRNVHEDEKEIKCLERKVVDLLASHIKDK-GFYDVTTTTSQRRIKCKCETDTFVQYKLRKCQESLEEVKCVNNKFIGKRISYIQTKTANSNYDYDCVKKEEKVEK-EVICPRNSSKT---VGGEKSLTYFVIKN--CECVPQYYIPKPSCN 3658 The following BLAST results are available for this feature:
BLAST of VWFD domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 2
BLAST of VWFD domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 3
BLAST of VWFD domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of VWFD domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of VWFD domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of VWFD domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 4
BLAST of VWFD domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of VWFD domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034930 ID=SMED30034930|Name=VWFD domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=12236bpback to top protein sequence of SMED30034930-orf-1 >SMED30034930-orf-1 ID=SMED30034930-orf-1|Name=SMED30034930-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=4049bp MWRQWLTLLIITLSFYQFAKATRYGVCQNTKVEKEPCTNGTRNIRITTYVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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