G protein gamma domain-containing protein

Overview


Name	G protein gamma domain-containing protein
Smed ID	SMED30034920
Length (bp)	246

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of G protein gamma domain-containing protein (SMED30034920) t-SNE clustered cells

Violin plots show distribution of expression levels for G protein gamma domain-containing protein (SMED30034920) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of G protein gamma domain-containing protein (SMED30034920) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for G protein gamma domain-containing protein (SMED30034920) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034920

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 14

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
head region	SMED30034920	SMESG000066557.1	SmedASXL_006695	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
protonephridia	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neoblast	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
muscle cell	SMED30034920	SMESG000066557.1	dd_Smed_v4_1237_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
head region	SMED30034920	SMESG000066557.1	dd_Smed_v6_1237_0_1	dd_Smed_v6	PMID:28171748 Stückemann et al., 2017
photoreceptor neuron	SMED30034920	SMESG000066557.1	SMED30020678	smed_20140614	PMID:22884275 Lapan et al., 2012
neuron	SMED30034920	SMESG000066557.1	dd_Smed_v6_1237_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
cholinergic neuron	SMED30034920	SMESG000066557.1	dd_Smed_v6_1237_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
parenchymal cell	SMED30034920	SMESG000066557.1	dd_Smed_v6_1237_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018
GABAergic neuron	SMED30034920	SMESG000066557.1	dd_Smed_v6_1237_0	dd_Smed_v6	PMID:29674432 Plass et al., 2018

Note: Hover over icons to view figure legend

Homology

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BLAST of G protein gamma domain-containing protein vs. Ensembl Human
Match: GNG7 (G protein subunit gamma 7 [Source:HGNC Symbol;Acc:HGNC:4410])

HSP 1 Score: 43.8986 bits (102), Expect = 5.203e-7
Identity = 23/57 (40.35%), Postives = 36/57 (63.16%), Query Frame = 3

Query:   69 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    7 IAQARKLVEQLRIEAGIERIKVSKAASDLMSYCEQHARNDPLLVGVP-ASENPFKDK 62

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BLAST of G protein gamma domain-containing protein vs. Ensembl Human
Match: GNG3 (G protein subunit gamma 3 [Source:HGNC Symbol;Acc:HGNC:4405])

HSP 1 Score: 42.3578 bits (98), Expect = 2.675e-6
Identity = 21/58 (36.21%), Postives = 36/58 (62.07%), Query Frame = 3

Query:   66 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
             I Q +K+VEQL+ EA++ R  VS +  +++ Y D +  +D L++      +NPF+EK
Sbjct:   12 SIGQARKMVEQLKIEASLCRIKVSKAAADLMTYCDAHACEDPLITPVPT-SENPFREK 68

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BLAST of G protein gamma domain-containing protein vs. Ensembl Human
Match: GNG2 (G protein subunit gamma 2 [Source:HGNC Symbol;Acc:HGNC:4404])

HSP 1 Score: 42.3578 bits (98), Expect = 2.858e-6
Identity = 22/59 (37.29%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQL+ EA I+R  VS +  +++ Y + +  +D L++      +NPF+EK
Sbjct:    7 ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVP-ASENPFREK 64

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Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQL+ EA I+R  VS +  +++ Y + +  +D L++      +NPF+EK
Sbjct:    7 ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVP-ASENPFREK 64

[Close]

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQL+ EA I+R  VS +  +++ Y + +  +D L++      +NPF+EK
Sbjct:    7 ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVP-ASENPFREK 64

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BLAST of G protein gamma domain-containing protein vs. Ensembl Celegans
Match: gpc-1 (Guanine nucleotide-binding protein subunit gamma [Source:UniProtKB/Swiss-Prot;Acc:P54406])

HSP 1 Score: 43.5134 bits (101), Expect = 2.491e-7
Identity = 24/50 (48.00%), Postives = 33/50 (66.00%), Query Frame = 3

Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
             EQL AEA I R+ VS   +E++ + ++NK  D LVSG  ++  NPFQEK
Sbjct:    8 TEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQH-NPFQEK 56

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Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
             EQL AEA I R+ VS   +E++ + ++NK  D LVSG  ++  NPFQEK
Sbjct:    8 TEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQH-NPFQEK 56

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Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
             EQL AEA I R+ VS   +E++ + ++NK  D LVSG  ++  NPFQEK
Sbjct:    8 TEQLCAEANIQRKKVSEVSKELLDFCEKNKTNDMLVSGPTDQH-NPFQEK 56

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BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
Match: Ggamma1 (gene:FBgn0004921 transcript:FBtr0088645)

HSP 1 Score: 64.3142 bits (155), Expect = 2.290e-15
Identity = 28/61 (45.90%), Postives = 46/61 (75.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSS 66

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
Match: Ggamma1 (gene:FBgn0004921 transcript:FBtr0088647)

HSP 1 Score: 64.3142 bits (155), Expect = 2.290e-15
Identity = 28/61 (45.90%), Postives = 46/61 (75.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSS 66

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
Match: Ggamma1 (gene:FBgn0004921 transcript:FBtr0088646)

HSP 1 Score: 64.3142 bits (155), Expect = 2.290e-15
Identity = 28/61 (45.90%), Postives = 46/61 (75.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSS 66

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
Match: CG43324 (gene:FBgn0263029 transcript:FBtr0306907)

HSP 1 Score: 56.225 bits (134), Expect = 3.181e-12
Identity = 26/61 (42.62%), Postives = 41/61 (67.21%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            + + QQ+ +  QLR E  + R PVS +   M++YM E++++DCL+SGF  +K NPF+EK  
Sbjct:    3 ANLQQQRSINLQLRREVEMERMPVSVACSLMMKYMLEHEEEDCLLSGF-TQKVNPFREKSS 62

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BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
Match: Ggamma30A (gene:FBgn0267252 transcript:FBtr0336620)

HSP 1 Score: 45.0542 bits (105), Expect = 7.948e-8
Identity = 21/54 (38.89%), Postives = 38/54 (70.37%), Query Frame = 3

Query:   81 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKG 242
            KK +E ++ +A++ R P+S S+ EM  +++EN+  D L++   +KK+NP+ EKG
Sbjct:    7 KKQIENMKYQASMERWPLSKSIAEMRSFIEENEKNDPLINA-PDKKNNPWAEKG 59

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BLAST of G protein gamma domain-containing protein vs. Ensembl Zebrafish
Match: si:dkey-117i10.1 (si:dkey-117i10.1 [Source:ZFIN;Acc:ZDB-GENE-091204-371])

HSP 1 Score: 46.2098 bits (108), Expect = 5.167e-8
Identity = 22/62 (35.48%), Postives = 39/62 (62.90%), Query Frame = 3

Query:   54 Y*MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            Y  + + Q ++ VEQLR E  + R  +SA+ ++++QY  E++  D L++G A    NPF++K
Sbjct:    4 YCSNNVLQARRAVEQLRMETELQRIKISAAAEQLVQYCQEHRRADPLLTGIA-ASSNPFKDK 64

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BLAST of G protein gamma domain-containing protein vs. Ensembl Zebrafish
Match: gngt1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7596])

HSP 1 Score: 45.8246 bits (107), Expect = 7.248e-8
Identity = 24/62 (38.71%), Postives = 36/62 (58.06%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            M+ + + K  V QL+ E  + R  VS   +E+ +Y+    D+D LV G   +K NPF+EKGG
Sbjct:    9 MTDLDKAKMEVTQLKTEVKLERAKVSKCCEEITEYIQGGADEDPLVKGIPEEK-NPFKEKGG 69

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Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            M+ + + K  V QL+ E  + R  VS   +E+ +Y+    D+D LV G   +K NPF+EKGG
Sbjct:    9 MTDLDKAKMEVTQLKTEVKLERAKVSKCCEEITEYIQGGADEDPLVKGIPEEK-NPFKEKGG 69

[Close]

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            M+ + + K  V QL+ E  + R  VS   +E+ +Y+    D+D LV G   +K NPF+EKGG
Sbjct:    9 MTDLDKAKMEVTQLKTEVKLERAKVSKCCEEITEYIQGGADEDPLVKGIPEEK-NPFKEKGG 69

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Zebrafish
Match: gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:ZFIN;Acc:ZDB-GENE-040718-93])

HSP 1 Score: 44.669 bits (104), Expect = 1.725e-7
Identity = 23/57 (40.35%), Postives = 36/57 (63.16%), Query Frame = 3

Query:   69 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    7 IAQARKLVEQLRIEAGIERIKVSKAAADLMSYCEQHARSDPLLVGVPT-SENPFKDK 62

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BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
Match: gngt2 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2 [Source:NCBI gene;Acc:100124867])

HSP 1 Score: 47.7506 bits (112), Expect = 1.363e-8
Identity = 22/52 (42.31%), Postives = 33/52 (63.46%), Query Frame = 3

Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            VEQL+ E    R P+S S+ EM  Y++ +  +D L+ G  + + NPF+EKGG
Sbjct:   15 VEQLKKEVKTERAPISTSLSEMKTYIESHATEDPLIKGVPDDR-NPFKEKGG 65

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
Match: gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:NCBI gene;Acc:549887])

HSP 1 Score: 44.669 bits (104), Expect = 3.021e-7
Identity = 23/59 (38.98%), Postives = 37/59 (62.71%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    5 NNIAQARKLVEQLRLEAGIERIKVSKAAADLMNYCEQHAKNDPLLVGVPT-SENPFKDK 62

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
Match: hsd11b2 (hydroxysteroid (11-beta) dehydrogenase 2 [Source:Xenbase;Acc:XB-GENE-1012826])

HSP 1 Score: 43.8986 bits (102), Expect = 5.674e-7
Identity = 24/52 (46.15%), Postives = 31/52 (59.62%), Query Frame = 3

Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            VEQLR E    R  VS S+ E+  Y++ +  +D LV G    K NPF+EKGG
Sbjct:   15 VEQLRKEVKTERIMVSKSIPEIKSYIESHMSEDPLVKGVPEDK-NPFKEKGG 65

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
Match: kdm1a (lysine (K)-specific demethylase 1A [Source:Xenbase;Acc:XB-GENE-5816927])

HSP 1 Score: 42.3578 bits (98), Expect = 1.872e-6
Identity = 24/63 (38.10%), Postives = 39/63 (61.90%), Query Frame = 3

Query:   60 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            MSG   +S  KK+V QLR EA++NR  VS +  ++ Q+  +N   D L++G ++   NPF+ +
Sbjct:    1 MSGPANVSAMKKVVHQLRLEASLNRVKVSQAAADLKQFCLQNAQHDPLLTGVSS-STNPFRPQ 62

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
Match: gng2 (guanine nucleotide binding protein (G protein), gamma 2 [Source:NCBI gene;Acc:448567])

HSP 1 Score: 42.3578 bits (98), Expect = 2.591e-6
Identity = 22/59 (37.29%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQL+ EA I+R  VS +  +++ Y + +  +D L++      +NPF+EK
Sbjct:    7 ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVP-ASENPFREK 64

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Mouse
Match: Gm5741 (predicted gene 5741 [Source:MGI Symbol;Acc:MGI:3645690])

HSP 1 Score: 44.2838 bits (103), Expect = 2.554e-7
Identity = 24/59 (40.68%), Postives = 33/59 (55.93%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            S I Q ++ VEQLR EA INR  VS +  +++Q+  E    D  + G      NPF+EK
Sbjct:    9 SDIGQARRAVEQLRMEAGINRIKVSKAATDLLQFCTEQAKSDPFLVGIP-AATNPFKEK 66

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Mouse
Match: Gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:MGI Symbol;Acc:MGI:95787])

HSP 1 Score: 43.1282 bits (100), Expect = 7.638e-7
Identity = 25/63 (39.68%), Postives = 39/63 (61.90%), Query Frame = 3

Query:   60 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            MSG   ++Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    1 MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVP-ASENPFKDK 62

[Close]

Query:   60 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            MSG   ++Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    1 MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVP-ASENPFKDK 62

[Close]

Query:   60 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            MSG   ++Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    1 MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVP-ASENPFKDK 62

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Mouse
Match: Gng7 (guanine nucleotide binding protein (G protein), gamma 7 [Source:MGI Symbol;Acc:MGI:95787])

HSP 1 Score: 43.1282 bits (100), Expect = 7.807e-7
Identity = 25/63 (39.68%), Postives = 39/63 (61.90%), Query Frame = 3

Query:   60 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            MSG   ++Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    2 MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSDLMGYCEQHARNDPLLVGVP-ASENPFKDK 63

[Close]

BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
Match: sp|P38040|GBG1_DROME (Guanine nucleotide-binding protein subunit gamma-1 OS=Drosophila melanogaster OX=7227 GN=Ggamma1 PE=2 SV=1)

HSP 1 Score: 64.3142 bits (155), Expect = 2.296e-14
Identity = 28/61 (45.90%), Postives = 46/61 (75.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            S + QQ+ +VEQLR EAAI+R+ +S S  +M++Y+ E++ +D L++GF ++K NPF+EK  
Sbjct:    6 SSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSS 66

[Close]

BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
Match: sp|Q4VT26|GBG_CAEBR (Guanine nucleotide-binding protein subunit gamma OS=Caenorhabditis briggsae OX=6238 GN=gpc-1 PE=3 SV=1)

HSP 1 Score: 45.4394 bits (106), Expect = 6.835e-7
Identity = 24/53 (45.28%), Postives = 34/53 (64.15%), Query Frame = 3

Query:   81 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            K   EQLR EA I R+ VS   ++++++ ++NK  D LVSG  +   NPFQEK
Sbjct:    5 KTTTEQLRTEANIQRKKVSEVAKDLVEFCEKNKATDMLVSGPLD-AHNPFQEK 56

[Close]

BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
Match: sp|P43425|GBG7_RAT (Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 OS=Rattus norvegicus OX=10116 GN=Gng7 PE=2 SV=2)

HSP 1 Score: 45.0542 bits (105), Expect = 8.071e-7
Identity = 26/63 (41.27%), Postives = 39/63 (61.90%), Query Frame = 3

Query:   60 MSG---ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            MSG   ++Q +KLVEQLR EA I R  VS +  E++ Y +++   D L+ G     +NPF++K
Sbjct:    1 MSGTNNVAQARKLVEQLRIEAGIERIKVSKASSELMSYCEQHARNDPLLVGVP-ASENPFKDK 62

[Close]

BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
Match: sp|Q9NFZ3|GBGE_DROME (Guanine nucleotide-binding protein subunit gamma-e OS=Drosophila melanogaster OX=7227 GN=Ggamma30A PE=1 SV=1)

HSP 1 Score: 45.0542 bits (105), Expect = 9.312e-7
Identity = 21/54 (38.89%), Postives = 38/54 (70.37%), Query Frame = 3

Query:   81 KKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKG 242
            KK +E ++ +A++ R P+S S+ EM  +++EN+  D L++   +KK+NP+ EKG
Sbjct:   15 KKQIENMKYQASMERWPLSKSIAEMRSFIEENEKNDPLINA-PDKKNNPWAEKG 67

[Close]

BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
Match: sp|P30671|GBG7_BOVIN (Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 OS=Bos taurus OX=9913 GN=GNG7 PE=1 SV=1)

HSP 1 Score: 44.669 bits (104), Expect = 1.220e-6
Identity = 24/57 (42.11%), Postives = 36/57 (63.16%), Query Frame = 3

Query:   69 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            I+Q +KLVEQLR EA I R  VS +  E++ Y +++   D L+ G     +NPF++K
Sbjct:    7 IAQARKLVEQLRIEAGIERIKVSKASSELMSYCEQHARNDPLLVGVP-ASENPFKDK 62

[Close]

BLAST of G protein gamma domain-containing protein vs. TrEMBL
Match: Q8IT61 (Guanine nucleotide-binding protein subunit gamma; Trimeric G-protein gamma subunit OS=Schistosoma mansoni OX=6183 PE=2 SV=1)

HSP 1 Score: 106.301 bits (264), Expect = 1.799e-28
Identity = 49/62 (79.03%), Postives = 56/62 (90.32%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N+DKDCLVSGFA+KKDNPFQEKGG
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNRDKDCLVSGFASKKDNPFQEKGG 62

[Close]

BLAST of G protein gamma domain-containing protein vs. TrEMBL
Match: A0A183WBU9 (G protein gamma domain-containing protein OS=Trichobilharzia regenti OX=157069 GN=TRE_LOCUS9602 PE=4 SV=1)

HSP 1 Score: 105.916 bits (263), Expect = 2.949e-28
Identity = 49/62 (79.03%), Postives = 56/62 (90.32%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            MS +SQQ+KLVEQLR EA INRRPVS  VQ+MI YM++N+DKDCLVSGFA+KKDNPFQEKGG
Sbjct:    1 MSTLSQQRKLVEQLRQEANINRRPVSECVQDMIVYMEQNRDKDCLVSGFASKKDNPFQEKGG 62

[Close]

BLAST of G protein gamma domain-containing protein vs. TrEMBL
Match: A0A183JX55 (G protein gamma domain-containing protein OS=Schistosoma curassoni OX=6186 GN=SCUD_LOCUS7300 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 7.917e-28
Identity = 48/62 (77.42%), Postives = 56/62 (90.32%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N++KDCLVSGFA+KKDNPFQEKGG
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNREKDCLVSGFASKKDNPFQEKGG 62

[Close]

BLAST of G protein gamma domain-containing protein vs. TrEMBL
Match: A0A183N8Z7 (G protein gamma domain-containing protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS24772 PE=4 SV=1)

HSP 1 Score: 104.76 bits (260), Expect = 7.917e-28
Identity = 48/62 (77.42%), Postives = 56/62 (90.32%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N++KDCLVSGFA+KKDNPFQEKGG
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNREKDCLVSGFASKKDNPFQEKGG 62

[Close]

BLAST of G protein gamma domain-containing protein vs. TrEMBL
Match: G4M241 (G protein gamma domain-containing protein OS=Schistosoma mansoni OX=6183 GN=Smp_205760 PE=4 SV=1)

HSP 1 Score: 103.99 bits (258), Expect = 1.215e-27
Identity = 48/62 (77.42%), Postives = 55/62 (88.71%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            MS +SQQ+KLVEQLR EA +NRRPVS  VQEMI YM++N+DKDCL SGFA+KKDNPFQEKGG
Sbjct:    1 MSTLSQQRKLVEQLRQEANLNRRPVSECVQEMIVYMEQNRDKDCLFSGFASKKDNPFQEKGG 62

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Cavefish
Match: gng7 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [Source:NCBI gene;Acc:103035574])

HSP 1 Score: 45.4394 bits (106), Expect = 7.290e-8
Identity = 23/57 (40.35%), Postives = 36/57 (63.16%), Query Frame = 3

Query:   69 ISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            I+Q +KLVEQLR EA I R  VS +  +++ Y +++   D L+ G     +NPF++K
Sbjct:    7 IAQARKLVEQLRIEAGIERIKVSKAAADLMSYCEQHARSDALLVGVPT-SENPFKDK 62

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Cavefish
Match: gngt1 (guanine nucleotide-binding protein G(T) subunit gamma-T1 [Source:NCBI gene;Acc:103023645])

HSP 1 Score: 45.4394 bits (106), Expect = 9.484e-8
Identity = 22/62 (35.48%), Postives = 38/62 (61.29%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            ++ + + K  V QL+ E  + R  VS   +E+++Y+    ++D LV G + +K NPF+EKGG
Sbjct:    9 LTDLDKAKMEVTQLKVEVKLEREKVSKCCEEVMEYIQAGVEEDILVKGISEEK-NPFKEKGG 69

[Close]

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            ++ + + K  V QL+ E  + R  VS   +E+++Y+    ++D LV G + +K NPF+EKGG
Sbjct:    9 LTDLDKAKMEVTQLKVEVKLEREKVSKCCEEVMEYIQAGVEEDILVKGISEEK-NPFKEKGG 69

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Cavefish
Match: gng2 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [Source:NCBI gene;Acc:103030920])

HSP 1 Score: 43.1282 bits (100), Expect = 6.908e-7
Identity = 23/59 (38.98%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQL+ EA I+R  VS +  +++ Y + +  +D L+S      +NPF+EK
Sbjct:    7 ASIAQARKLVEQLKMEANIDRIKVSKAAADLMSYCEAHAKEDPLLSPVP-ASENPFREK 64

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Cavefish
Match: gngt2b (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 [Source:NCBI gene;Acc:103025140])

HSP 1 Score: 42.3578 bits (98), Expect = 1.413e-6
Identity = 21/52 (40.38%), Postives = 32/52 (61.54%), Query Frame = 3

Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            ++QL+ E   +R  VSA+  ++I Y++    +D LV G    K NPF+EKGG
Sbjct:   15 LDQLKIEVKTSRTAVSATAPDIISYVEARSGEDPLVKGVPEDK-NPFKEKGG 65

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Sea Lamprey
Match: gngt2b (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b [Source:ZFIN;Acc:ZDB-GENE-091020-4])

HSP 1 Score: 39.2762 bits (90), Expect = 4.891e-6
Identity = 20/51 (39.22%), Postives = 29/51 (56.86%), Query Frame = 3

Query:   93 EQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            EQLR E  + R  +S    +++ +++ N   D LV G    K NPF+EKGG
Sbjct:   17 EQLRIEVKLTREKISKVAPDILAHVESNMADDPLVKGVPEDK-NPFKEKGG 66

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
Match: si:dkey-117i10.1 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12-like [Source:NCBI gene;Acc:110015484])

HSP 1 Score: 47.7506 bits (112), Expect = 9.122e-9
Identity = 24/58 (41.38%), Postives = 37/58 (63.79%), Query Frame = 3

Query:   66 GISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
             + Q +KLVEQLR EA++ R  +S +  +++QY  E++  D L+ G A    NPF+EK
Sbjct:   12 SVIQAQKLVEQLRLEASMVRFKISLTAADLVQYCQEHRCSDPLLMGIA-ASSNPFKEK 68

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
Match: gng2 (G protein subunit gamma 2 [Source:NCBI gene;Acc:101157742])

HSP 1 Score: 44.669 bits (104), Expect = 1.732e-7
Identity = 24/59 (40.68%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I+Q +KLVEQL+ EA I+R  VS +  E++ Y + +  +D L+S      +NPF+EK
Sbjct:   14 ASIAQARKLVEQLKMEANIDRIKVSKAAAELMSYCEAHAKEDPLLSPVP-ASENPFREK 71

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
Match: gng5 (guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 [Source:NCBI gene;Acc:110016922])

HSP 1 Score: 43.8986 bits (102), Expect = 2.849e-7
Identity = 24/57 (42.11%), Postives = 36/57 (63.16%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQ 233
            S I   KK+V+QLR EA+INR  VS +  E+ Q+   N  +D L++G ++   NPF+
Sbjct:    5 SSIVAMKKVVQQLRYEASINRVKVSQAAAELQQFCMNNATQDPLLTGMSS-STNPFR 60

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
Match: gngt1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Source:ZFIN;Acc:ZDB-GENE-030131-7596])

HSP 1 Score: 43.8986 bits (102), Expect = 3.660e-7
Identity = 22/52 (42.31%), Postives = 32/52 (61.54%), Query Frame = 3

Query:   90 VEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            V QL+ E  + R   S   +EM +Y+ E  ++D LV G + +K NPF+EKGG
Sbjct:   19 VNQLKLEVKLERWLTSKCCEEMKEYIQERVEEDTLVKGISEEK-NPFKEKGG 69

[Close]

BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
Match: GNG5 (G protein subunit gamma 5 [Source:NCBI gene;Acc:111947358])

HSP 1 Score: 42.3578 bits (98), Expect = 1.083e-6
Identity = 21/59 (35.59%), Postives = 38/59 (64.41%), Query Frame = 3

Query:   63 SGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEK 239
            + I   KK+++QLR EA+INR  VS +  ++ Q+  +N   D L++G ++  +NPF+ +
Sbjct:    3 ANIVTMKKIIQQLRLEASINRVKVSQAATDLQQFCLQNAQHDPLLTGMSS-SNNPFRPQ 60

[Close]

BLAST of G protein gamma domain-containing protein vs. Planmine SMEST
Match: SMESG000066557.1 (SMESG000066557.1)

HSP 1 Score: 128.257 bits (321), Expect = 9.024e-41
Identity = 62/62 (100.00%), Postives = 62/62 (100.00%), Query Frame = 3

Query:   60 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 245
            MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG
Sbjct:    1 MSGISQQKKLVEQLRAEAAINRRPVSASVQEMIQYMDENKDKDCLVSGFANKKDNPFQEKGG 62

The following BLAST results are available for this feature:

BLAST of G protein gamma domain-containing protein vs. Ensembl Human
BLAST of G protein gamma domain-containing protein vs. Ensembl Celegans
BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
BLAST of G protein gamma domain-containing protein vs. Ensembl Zebrafish
BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
BLAST of G protein gamma domain-containing protein vs. Ensembl Mouse
BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
BLAST of G protein gamma domain-containing protein vs. TrEMBL
BLAST of G protein gamma domain-containing protein vs. Ensembl Cavefish
BLAST of G protein gamma domain-containing protein vs. Ensembl Sea Lamprey
BLAST of G protein gamma domain-containing protein vs. Ensembl Yeast
BLAST of G protein gamma domain-containing protein vs. Ensembl Nematostella
BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
BLAST of G protein gamma domain-containing protein vs. Planmine SMEST

BLAST of G protein gamma domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
GNG7	5.203e-7	40.35	G protein subunit gamma 7 [Source:HGNC Symbol;Acc:...	[more]
GNG3	2.675e-6	36.21	G protein subunit gamma 3 [Source:HGNC Symbol;Acc:...	[more]
GNG2	2.858e-6	37.29	G protein subunit gamma 2 [Source:HGNC Symbol;Acc:...	[more]
GNG2	2.858e-6	37.29	G protein subunit gamma 2 [Source:HGNC Symbol;Acc:...	[more]
GNG2	2.858e-6	37.29	G protein subunit gamma 2 [Source:HGNC Symbol;Acc:...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 3


Match Name	E-value	Identity	Description
gpc-1	2.491e-7	48.00	Guanine nucleotide-binding protein subunit gamma ...	[more]
gpc-1	2.491e-7	48.00	Guanine nucleotide-binding protein subunit gamma ...	[more]
gpc-1	2.491e-7	48.00	Guanine nucleotide-binding protein subunit gamma ...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Ggamma1	2.290e-15	45.90	gene:FBgn0004921 transcript:FBtr0088645	[more]
Ggamma1	2.290e-15	45.90	gene:FBgn0004921 transcript:FBtr0088647	[more]
Ggamma1	2.290e-15	45.90	gene:FBgn0004921 transcript:FBtr0088646	[more]
CG43324	3.181e-12	42.62	gene:FBgn0263029 transcript:FBtr0306907	[more]
Ggamma30A	7.948e-8	38.89	gene:FBgn0267252 transcript:FBtr0336620	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-117i10.1	5.167e-8	35.48	si:dkey-117i10.1 [Source:ZFIN;Acc:ZDB-GENE-091204-...	[more]
gngt1	7.248e-8	38.71	guanine nucleotide binding protein (G protein), ga...	[more]
gngt1	7.248e-8	38.71	guanine nucleotide binding protein (G protein), ga...	[more]
gngt1	7.248e-8	38.71	guanine nucleotide binding protein (G protein), ga...	[more]
gng7	1.725e-7	40.35	guanine nucleotide binding protein (G protein), ga...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gngt2	1.363e-8	42.31	guanine nucleotide binding protein (G protein), ga...	[more]
gng7	3.021e-7	38.98	guanine nucleotide binding protein (G protein), ga...	[more]
hsd11b2	5.674e-7	46.15	hydroxysteroid (11-beta) dehydrogenase 2 [Source:X...	[more]
kdm1a	1.872e-6	38.10	lysine (K)-specific demethylase 1A [Source:Xenbase...	[more]
gng2	2.591e-6	37.29	guanine nucleotide binding protein (G protein), ga...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Gm5741	2.554e-7	40.68	predicted gene 5741 [Source:MGI Symbol;Acc:MGI:364...	[more]
Gng7	7.638e-7	39.68	guanine nucleotide binding protein (G protein), ga...	[more]
Gng7	7.638e-7	39.68	guanine nucleotide binding protein (G protein), ga...	[more]
Gng7	7.638e-7	39.68	guanine nucleotide binding protein (G protein), ga...	[more]
Gng7	7.807e-7	39.68	guanine nucleotide binding protein (G protein), ga...	[more]

BLAST of G protein gamma domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|P38040\|GBG1_DROME	2.296e-14	45.90	Guanine nucleotide-binding protein subunit gamma-1...	[more]
sp\|Q4VT26\|GBG_CAEBR	6.835e-7	45.28	Guanine nucleotide-binding protein subunit gamma O...	[more]
sp\|P43425\|GBG7_RAT	8.071e-7	41.27	Guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]
sp\|Q9NFZ3\|GBGE_DROME	9.312e-7	38.89	Guanine nucleotide-binding protein subunit gamma-e...	[more]
sp\|P30671\|GBG7_BOVIN	1.220e-6	42.11	Guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]

BLAST of G protein gamma domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
Q8IT61	1.799e-28	79.03	Guanine nucleotide-binding protein subunit gamma; ...	[more]
A0A183WBU9	2.949e-28	79.03	G protein gamma domain-containing protein OS=Trich...	[more]
A0A183JX55	7.917e-28	77.42	G protein gamma domain-containing protein OS=Schis...	[more]
A0A183N8Z7	7.917e-28	77.42	G protein gamma domain-containing protein OS=Schis...	[more]
G4M241	1.215e-27	77.42	G protein gamma domain-containing protein OS=Schis...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
gng7	7.290e-8	40.35	guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]
gngt1	9.484e-8	35.48	guanine nucleotide-binding protein G(T) subunit ga...	[more]
gngt1	9.484e-8	35.48	guanine nucleotide-binding protein G(T) subunit ga...	[more]
gng2	6.908e-7	38.98	guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]
gngt2b	1.413e-6	40.38	guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
gngt2b	4.891e-6	39.22	guanine nucleotide binding protein (G protein), ga...	[more]

BLAST of G protein gamma domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G protein gamma domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of G protein gamma domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5


Match Name	E-value	Identity	Description
si:dkey-117i10.1	9.122e-9	41.38	guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]
gng2	1.732e-7	40.68	G protein subunit gamma 2 [Source:NCBI gene;Acc:10...	[more]
gng5	2.849e-7	42.11	guanine nucleotide-binding protein G(I)/G(S)/G(O) ...	[more]
gngt1	3.660e-7	42.31	guanine nucleotide binding protein (G protein), ga...	[more]
GNG5	1.083e-6	35.59	G protein subunit gamma 5 [Source:NCBI gene;Acc:11...	[more]

BLAST of G protein gamma domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 1


Match Name	E-value	Identity	Description
SMESG000066557.1	9.024e-41	100.00	SMESG000066557.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence

transcript sequence

>SMED30034920 ID=SMED30034920|Name=G protein gamma domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=246bp
GTTCTTACTTACACTTAATCATGCATAATTAATTCAACAATTCAATTAAA
AATTATTAAATGTCTGGAATTAGTCAACAGAAAAAACTAGTCGAACAATT
ACGAGCAGAAGCTGCAATTAACCGGAGACCAGTTTCAGCCAGTGTTCAAG
AAATGATTCAATACATGGATGAAAACAAAGATAAAGACTGTTTAGTAAGT
GGGTTTGCTAACAAAAAGGACAATCCTTTCCAAGAAAAAGGTGGAT

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **molecular function**
Term	Definition
GO:0003924	GTPase activity
GO:0004871	signal transducer activity

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000017	photoreceptor neuron
PLANA:0000020	protonephridia
PLANA:0000099	neuron
PLANA:0000101	muscle cell
PLANA:0000418	head
PLANA:0000463	cholinergic neuron
PLANA:0000464	GABAergic neuron
PLANA:0003116	parenchymal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR036284	GGL_sf
IPR001770	Gprotein-gamma
IPR015898	G-protein_gamma-like_dom

Vocabulary: **biological process**
Term	Definition
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007165	signal transduction

Vocabulary: **cellular component**
Term	Definition
GO:0005834	heterotrimeric G-protein complex

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	SMART	SM01224	G_gamma_2	coord: 1..59 e-value: 2.0E-9 score: 47.3
None	No IPR available	PANTHER	PTHR13809:SF48	GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT GAMMA-RELATED	coord: 1..61
IPR015898	G-protein gamma-like domain	SMART	SM00224	GGL_4	coord: 4..62 e-value: 2.0E-10 score: 50.6
IPR015898	G-protein gamma-like domain	PFAM	PF00631	G-gamma	coord: 6..60 e-value: 8.4E-12 score: 44.9
IPR015898	G-protein gamma-like domain	PROSITE	PS50058	G_PROTEIN_GAMMA	coord: 1..62 score: 19.095
IPR015898	G-protein gamma-like domain	CDD	cd00068	GGL	coord: 4..61 e-value: 7.41626E-15 score: 59.6102
IPR036284	G-protein gamma-like domain superfamily	GENE3D	G3DSA:4.10.260.10		coord: 2..60 e-value: 4.0E-22 score: 79.9
IPR036284	G-protein gamma-like domain superfamily	SUPERFAMILY	SSF48670	Transducin (heterotrimeric G protein), gamma chain	coord: 2..61
IPR001770	G-protein, gamma subunit	PANTHER	PTHR13809	GUANINE NUCLEOTIDE-BINDING PROTEIN GAMMA SUBUNIT	coord: 1..61

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G protein gamma domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 14

Owlery

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