glypican-1
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034893 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of glypican-1 vs. Ensembl Human
Match: GPC4 (glypican 4 [Source:HGNC Symbol;Acc:HGNC:4452]) HSP 1 Score: 113.62 bits (283), Expect = 1.622e-25 Identity = 87/374 (23.26%), Postives = 162/374 (43.32%), Query Frame = 3 Query: 219 ICPK-TTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKN-NAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQ--CWNG 1313 ICP+ +TCC M+ + S+ KS+ + + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y N+E++L+ F+ + E++ R+ + E + C++ +L P+ +V + + A+ AR L A DV +S + P+ +CT K YCS C L PC C +I+ C + ++ W + A+ ++ + + PFN V + + +KIS+A+MN+ + + K+ C R R+ E + S F + L+ LV + K+K + + +C+ GN+ CWNG Sbjct: 59 ICPQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVS-VVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLAN-----QGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNG 426
BLAST of glypican-1 vs. Ensembl Human
Match: GPC6 (glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454]) HSP 1 Score: 112.079 bits (279), Expect = 4.834e-25 Identity = 67/289 (23.18%), Postives = 137/289 (47.40%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ICP+ TCC M+ ++ S+++ +++ E + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y G N+E++L+ F+ + E++ ++ + +E + C++ +L P+ +V + + A+ AR V L +V +S K+ P+ C K YC +C L PC+ C +++ C + ++ W + A+ ++ + + PFN V + + +KISEA+MN+ + K+ C Sbjct: 59 ICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVS-KVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLAN-----QADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGC 341
BLAST of glypican-1 vs. Ensembl Human
Match: GPC1 (glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449]) HSP 1 Score: 103.605 bits (257), Expect = 2.716e-22 Identity = 83/380 (21.84%), Postives = 157/380 (41.32%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRM---SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLI--------RKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQG-NQCWNG 1313 ICP+ TCC + M+ + S +L++ + + +L R +D +Q+ L+ S+ + F + Y N R D Y +L+LY G ++E+ L F+ + E++ + +L ++ + CL L P+ + + A+ AR V L A DV ++Q L P EC+ K YC+ C + PC C++++ C + ++ W+ LL ++ I++K V ++H ++EA+ + + ++ K+ C N + KRR K +P L LV++ +++D+ + +CS L ++CWNG Sbjct: 61 ICPQGYTCCTSEMEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDD--YLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGP--ECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLAN-----QADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRRG-------------KLAPRERPPSGTLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMALSTASDDRCWNG 418
BLAST of glypican-1 vs. Ensembl Human
Match: GPC1 (glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449]) HSP 1 Score: 91.6633 bits (226), Expect = 1.312e-18 Identity = 77/368 (20.92%), Postives = 149/368 (40.49%), Query Frame = 3 Query: 252 MKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRM---SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLI--------RKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQG-NQCWNG 1313 M+ + S +L++ + + +L R +D +Q+ L+ S+ + F + Y N R D Y +L+LY G ++E+ L F+ + E++ + +L ++ + CL L P+ + + A+ AR V L A DV ++Q L P EC+ K YC+ C + PC C++++ C + ++ W+ LL ++ I++K V ++H ++EA+ + + ++ K+ C N + KRR K +P L LV++ +++D+ + +CS L ++CWNG Sbjct: 1 MEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDD--YLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGP--ECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLAN-----QADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGNPKVNPQGPGPEEKRRRG-------------KLAPRERPPSGTLEKLVSEAKAQLRDVQDFWISLPGTLCSEKMALSTASDDRCWNG 346
BLAST of glypican-1 vs. Ensembl Human
Match: GPC1 (glypican 1 [Source:HGNC Symbol;Acc:HGNC:4449]) HSP 1 Score: 84.7297 bits (208), Expect = 3.005e-17 Identity = 62/282 (21.99%), Postives = 121/282 (42.91%), Query Frame = 3 Query: 252 MKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKI---LRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN 1082 M+ + S +L++ + + +L R +D +Q+ L+ S+ + F + Y N R D Y +L+LY G ++E+ L F+ + E++ L +L ++ + CL L P+ + + A+ AR V L A DV ++Q L P EC+ K YC+ C + PC C++++ C + ++ W+ LL ++ I++K V ++H ++EA+ + + ++ K+ C N Sbjct: 1 MEENLANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDD--YLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGP--ECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLKGCLAN-----QADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINALQDNRDTLTAKVIQGCGN 273
BLAST of glypican-1 vs. Ensembl Celegans
Match: gpn-1 (GlyPicaN [Source:UniProtKB/TrEMBL;Acc:G5EGU4]) HSP 1 Score: 94.3597 bits (233), Expect = 8.002e-20 Identity = 75/344 (21.80%), Postives = 151/344 (43.90%), Query Frame = 3 Query: 321 IIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLY-MDGKEQNIEKILDTFFTEMAEKILRMS--ILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDV---FLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC----ENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEI 1322 I L + R N+F+ L ++ MF TY S Y++N + L DF+ K+K + + E +++ I++ FF E+ + + ++ S N +++ C+ + + ++ + ++ + IV+ + + SL + + + +L+++ K EC + C+ C PC C +I+ C +M AW+A ++ K+ N+ H N V + + ISEA+M+ I +K+ C E+ +RK+R+++ F+ P ++LN + KM + + N +C K+ +CWNG + Sbjct: 70 IRSFLTSQIRIFNEFFSKTLRTVHMDLDLMFSKTYGSFYQENIQLLNDFFKKIKGFSVSFAETSMKTIVELFFDELFQVMFSIANPFYSITNDQRV-CMESFYREIEAFDDIPQKIVNQLSLPLSNWKHFLGSLESLNGILEGYLNITFKE----ECERGLTRMETCAQCQRISEKPCQAYCVNILSGC-----THQMLDSEGAWRAATESMIKLGNQLNHRQNLVSALQPIPVLISEAIMHFQEKRDYITNKMIGKCLLNNEDFGLRKKRSAK-------FKAFPVITTKRSRDHLILNQMFQSFANKMDEWKVFFGNLPEYLCRGEDWASKEDERCWNGTGV 396
BLAST of glypican-1 vs. Ensembl Fly
Match: dlp (gene:FBgn0041604 transcript:FBtr0333032) HSP 1 Score: 98.5969 bits (244), Expect = 8.055e-21 Identity = 69/311 (22.19%), Postives = 141/311 (45.34%), Query Frame = 3 Query: 183 LLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKN---NAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMP---SIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRK 1097 +L++ S +V TCC M+T + S+ +L+ + + + +L + + D + L S+ Q N MF+ TY Y+ N D + +L+ Y ++ +++D FF + +K+ ++L+ + +RC++ +L P+ +V + K ++ R +L A +V ++K++ + +CT K +C C PC C ++I C ++ + W+ A++K++ + FN V V L++KISEA+MN + I +++ C ++K Sbjct: 106 VLRYCESPSVG------TCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMF--TVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEV----AKKVLNVRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGCL-----HYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKK 399
BLAST of glypican-1 vs. Ensembl Fly
Match: dlp (gene:FBgn0041604 transcript:FBtr0075679) HSP 1 Score: 98.5969 bits (244), Expect = 8.208e-21 Identity = 69/311 (22.19%), Postives = 141/311 (45.34%), Query Frame = 3 Query: 183 LLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKN---NAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMP---SIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRK 1097 +L++ S +V TCC M+T + S+ +L+ + + + +L + + D + L S+ Q N MF+ TY Y+ N D + +L+ Y ++ +++D FF + +K+ ++L+ + +RC++ +L P+ +V + K ++ R +L A +V ++K++ + +CT K +C C PC C ++I C ++ + W+ A++K++ + FN V V L++KISEA+MN + I +++ C ++K Sbjct: 106 VLRYCESPSVG------TCCTYNMETRMAMQSRQQLEGHTKDQISRMSGILGSKATKFKDIFTALLKESRTQFNSMFIRTYGVIYERNSYVFSDLFKELETYFANGRVDLLEVMDKFFNTLYQKMF--TVLNTQYTFDENYMRCVSEHMKELKPFGDVPDKLSVQIKRSFVATRTYGQALTTASEV----AKKVLNVRLNADCTGALTKMQHCGACKGYTEKPCTNYCVNVIKGCL-----HYQHEFDSEWENFAMAMDKVAERLLGSFNIVMVVEPLNIKISEAIMNFQDSGQDITNRVFQGCGRPKLKK 399
BLAST of glypican-1 vs. Ensembl Fly
Match: dally (gene:FBgn0263930 transcript:FBtr0305901) HSP 1 Score: 62.003 bits (149), Expect = 1.721e-9 Identity = 67/349 (19.20%), Postives = 140/349 (40.11%), Query Frame = 3 Query: 129 CQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYM---------DGK---------EQNIEKILDTFFTEM-AEKILRMSILSKNN-----AEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIE--CTTKYAKAFYCSWC------SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEK-ISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 C A+K+ Y S D+ T IC CC+NA + E+ + + + H S+ +L N++ IS++ + +F Y ++ + Y ++ ++ +G+ + N+E+ + FF ++ +M LSKNN + + CL ++F +++P+ ++ + + SN ++ + + +N+L A +V + + C K YC C S +ET C G CK+++ C + ++ W ++ +L ++ + V +L SEA+M + + K++ C Sbjct: 69 CDAVKS------YFESIDIKSSGTYSEKGAIC-GGNCCNNATELELRDKAAGMFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEY----AGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTC 406
BLAST of glypican-1 vs. Ensembl Fly
Match: dally (gene:FBgn0263930 transcript:FBtr0076583) HSP 1 Score: 62.003 bits (149), Expect = 1.721e-9 Identity = 67/349 (19.20%), Postives = 140/349 (40.11%), Query Frame = 3 Query: 129 CQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYM---------DGK---------EQNIEKILDTFFTEM-AEKILRMSILSKNN-----AEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIE--CTTKYAKAFYCSWC------SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEK-ISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 C A+K+ Y S D+ T IC CC+NA + E+ + + + H S+ +L N++ IS++ + +F Y ++ + Y ++ ++ +G+ + N+E+ + FF ++ +M LSKNN + + CL ++F +++P+ ++ + + SN ++ + + +N+L A +V + + C K YC C S +ET C G CK+++ C + ++ W ++ +L ++ + V +L SEA+M + + K++ C Sbjct: 69 CDAVKS------YFESIDIKSSGTYSEKGAIC-GGNCCNNATELELRDKAAGMFEQLLHHHTSSLRGVLETNAKQFQSHVLELAQISENMTHSLFSKVYTRMVPSSRMMIHQLYTEIMNHLIYTSNYTNSNGQLGRRGIGSVQSNLEEAVRHFFVQLFPVAYHQMVHLSKNNLGDLHEDYVNCLQHNFDEMHPFGDIPQQVQSNLGKSVHMSNVFMNALLQAAEVLSEADALYGEQLTDTCKLHLLKMHYCPNCNGHHSSSRSETKLCYGYCKNVMRGCSAEY----AGLLDSPWSGVVDSLNNLVTTHILSDTGIINVIKHLQTYFSEAIMAAMHNGPELEKKVKKTC 406
BLAST of glypican-1 vs. Ensembl Zebrafish
Match: gpc6b (glypican 6b [Source:ZFIN;Acc:ZDB-GENE-130515-2]) HSP 1 Score: 122.865 bits (307), Expect = 1.011e-28 Identity = 97/464 (20.91%), Postives = 203/464 (43.75%), Query Frame = 3 Query: 123 VDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILR-MSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETM-PCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQY--FENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAI----CSSTFKLPKQG----NQCWNGAE----ITTGYKPNVKEKDANKNLKI-----SPLVKTSIATLQKITAALNN 1439 ++C +K + + + D + T+ + + V P CC+ M+ S + + + + + + + + +DF+ L+ ++ +N+MF+ TY Y N + +L+ + G N+E++L F+T + E++ + ++ + E + C+ +L P+ +V K + S A+ AR V L DV ++Q M S C + + K YCS+C T+ PC C +++ C + +N W + AL ++ + + PFN V + +KISEA+MN+ + ++ C + R R+ + ++ +E +P ++ P+ ++L+++MK+ H Q++ ++ C ++ G QCWNG I K + ++ +N + + L++ I L+ ++ L N Sbjct: 19 LNCSLVKDAYSALGFSSDDVPAEQTSGEDLRVCAPLEACCNTQMEESFSHRSSHDFQKLMDDASEELRDTFMSGHKRFDDFFLELLESAERSLNEMFVRTYGKPYLQNAEVFQSLFSELRRFYTGGNVNLEEMLKDFWTRLLERMFQLLNSQFQITDEYLECIGKYTEQLRPFGDVPKKLKSQVTRAFIAARTFVQGLAVGRDVANRVAQVSMSS-SCVSGFTKMLYCSYCQGLFTLKPCRNYCLNVMKGCLAN-----QADLNNEWSKFIDALLLLTERLEGPFNIESVMEPIDVKISEAIMNMQENSMQLSYQVFQGCGQPEPAGMTRSARSVHDSFSGRFKPYEELPT---VASGAPL------HRLVSEMKEKLKHFQSFWVSLPLVFCKDE-QISADGQTEDQQCWNGHHSGRYIAEVQKDGLAQQASNPEVSVDVSRPDSLIRQQILALRIMSNKLKN 466
BLAST of glypican-1 vs. Ensembl Zebrafish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367]) HSP 1 Score: 115.161 bits (287), Expect = 3.125e-26 Identity = 95/398 (23.87%), Postives = 178/398 (44.72%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFL--------KLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVH---NFYTS-----IRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKT---LEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEIT-TGYKPNV 1346 ICP+ TCC +AM+ + +S+ + + + +SI LL R + ++ L+ S+ + + F++ Y+ N D Y +L Y G N+E+ LD F+ ++ E++L+ S + E L++ FL L P+ + + + + A+ AR V L AA ++ +SQ + S EC K YC C L PC CK+++ C + ++ W++L+ + ++++ + V ++ ++ISEAV+ + YTS D+ + + + + + E + ++ PK+ LE+ V + +K+K+M L+ +A+CS G++CWNG IT Y P V Sbjct: 58 ICPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKAS-----DPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKVSQVPL-SPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGCLAN-----QADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEEGTPSSISEEPKKKESTVTALEYKPSPKSAARLEVQ----------VTDVYSKLKEMQLYWIQLPSALCSGKTASSTTGDKCWNG--ITKASYLPEV 432
BLAST of glypican-1 vs. Ensembl Zebrafish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367]) HSP 1 Score: 115.161 bits (287), Expect = 3.703e-26 Identity = 95/398 (23.87%), Postives = 178/398 (44.72%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFL--------KLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVH---NFYTS-----IRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKT---LEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEIT-TGYKPNV 1346 ICP+ TCC +AM+ + +S+ + + + +SI LL R + ++ L+ S+ + + F++ Y+ N D Y +L Y G N+E+ LD F+ ++ E++L+ S + E L++ FL L P+ + + + + A+ AR V L AA ++ +SQ + S EC K YC C L PC CK+++ C + ++ W++L+ + ++++ + V ++ ++ISEAV+ + YTS D+ + + + + + E + ++ PK+ LE+ V + +K+K+M L+ +A+CS G++CWNG IT Y P V Sbjct: 67 ICPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKAS-----DPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKVSQVPL-SPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGCLAN-----QADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEEGTPSSISEEPKKKERTVTALEYKPSPKSAARLEVQ----------VTDVYSKLKEMQLYWIQLPSALCSGKTASSTTGDKCWNG--ITKASYLPEV 441
BLAST of glypican-1 vs. Ensembl Zebrafish
Match: gpc4 (glypican 4 [Source:ZFIN;Acc:ZDB-GENE-011119-1]) HSP 1 Score: 111.694 bits (278), Expect = 4.072e-25 Identity = 100/477 (20.96%), Postives = 204/477 (42.77%), Query Frame = 3 Query: 66 LLIITVLFALFENQNAQNDV---DCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMD--GKEQNIEKILDTFFTEMAEKILRM-SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETM-PCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC-ENKL---IRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAE--------ITTGYKPNVKEKDANKNL-KISPLVKTSIATLQKITAAL 1433 +++ TV ++ +AQ D +C ++T + S + +D K + V CP+ +CC M+ ++ +S + LK ++ R + F++ LD ++ +N MF+ TY Y N+ F+ L+ Y E N++ +L F++E+ E++ R+ ++ + + + C++ +L P+ +V + + ++ R L DV +S + S C K YC +CS + PC C +++ C + ++ W L ++ ++ + + PFNF V + + +KIS+A+MN+ + K+ C + KL R RR++++ F + L+ L+ + K+K + +C P + CWNG +++G V D ++ K +++ IA L+++T+ L Sbjct: 4 IVVFTVCMSVVVLASAQADQKSKNCNEVRTAYSSKGFNVNDVPNKGVQGAHLKV-CPQGFSCCTLEMEEKLSQLSHVDLKVPVHQLSSNLQSTFTQRHRHFDQFFRELLDNAEKSLNHMFVRTYGLMYVKNKELFEGFFSDLRRYYSHGSSEVNLDDMLAEFWSELLERMFRLVNVQYEFSDSYMECVSRHTDQLKPFGDVPRKLRLQLTRSFIAVRAFTRGLTLMPDVVRKVS-TVSASPSCVRASMKMLYCPYCSGQVALKPCKNYCLNVMRGCLAN-----QADLDTEWNNFLDSMLGLAERLEGPFNFESVVDPIDVKISDAIMNMQENSMQVSQKVFQGCGQPKLSMGFRSRRSAKDSGFPGRFRPYSPEARPTTAAGTTLDRLLTDVKKKLKHAKKFWSTLPDTVCVGERIAPS--DDCWNGTAKSRYESVVMSSGLANQVSNPDVEVDITKPDMVIRRQIAVLKEMTSWL 471
BLAST of glypican-1 vs. Ensembl Zebrafish
Match: gpc6a (glypican 6a [Source:ZFIN;Acc:ZDB-GENE-071004-15]) HSP 1 Score: 106.686 bits (265), Expect = 1.555e-23 Identity = 62/284 (21.83%), Postives = 139/284 (48.94%), Query Frame = 3 Query: 234 TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRM--SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 TCC + ++ ++ S++ + + + ++I + + ++F+ LD S+ +N MF+ TY Y N D + +LK Y G N+E++L+ F++ + E++ ++ S + ++ + + C++ +L P+ +V + + + +A+ AR V L +V + K+ S C+ K +YC +C ++ PC C++++ C + ++ W + A+ ++++ + PFN V + +KISEA+M + + + K+ C Sbjct: 64 TCCTSDIEDQLGQQSKLDFERLVDDSSRNIRTTFTSRHKKFDEFFLELLDNSEKSLNDMFVRTYGKLYTHNSEMFEDLFSELKRYYTGGNVNLEEVLNDFWSRLLERMFQLLNSQFTFSD-DYLECISKYTDQLKPFGDVPRKLKAQVTKAFIAARSFVQGLMVGREV-ANRVAKVNISPGCSKALTKMWYCPYCGGMSGLKPCANYCQNVMRGCLAN-----QADLDPEWNLFIDAMLLVADRLEGPFNIEAVMEPIDVKISEAIMTMQDNSMQVSSKVFQGC 340
BLAST of glypican-1 vs. Ensembl Xenopus
Match: GPC4 (glypican 4 [Source:NCBI gene;Acc:100126682]) HSP 1 Score: 116.701 bits (291), Expect = 1.375e-26 Identity = 86/403 (21.34%), Postives = 173/403 (42.93%), Query Frame = 3 Query: 129 CQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRM-SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCS-LTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAE 1319 C ++ + S + +D + V + TCC AM+ + S+ K ++ + + ++F++ L +++ +N MF+ TY Y N DF+ +LK Y G N+E++L+ F+ + E++ R+ + + E + C++ +L P+ +V + + A+ AR L A DV +S + P+ +C K YC +CS L PC+ C +++ C + ++ W + A+ ++ + + PFN V + + +KIS+A+MN+ + K+ C R+ R+ + + + F + + L+ LV + K+K + +IC + + + CWNG+E Sbjct: 30 CSEVRRLYISKGFNQNDAPTHEINGDHLKVCSQRHTCCSLAMEEKYSQQSKHDFKVAVIEPCNNMQHIFASRFNKFDEFFKELLQNAENSLNDMFVRTYGRLYMQNSELFKDFFVELKKYYVGGNVNLEEMLNDFWARLLERMFRLVNPQYQFTDEYLECVSKYTDQLKPFGDVPRKLKLQVTRAFVAARTFAQGLSVARDVINKVSS-VNPTPQCVKAMLKMTYCPYCSGLVTVKPCNNYCLNVMRGCLAN-----PGDLDTEWNNFIDAMLLVAERLEGPFNIETVMDPIDVKISDAIMNMQENSMQVSQKVFQGCGQPKPLSQGRQARSVSDSNFNSRFRSYGPEERPTTAAGTSLDRLVADVKEKLKTAKKFWSSLPGSICKNNWTSGASEDDCWNGSE 426
BLAST of glypican-1 vs. Ensembl Xenopus
Match: GPC6 (glypican 6 [Source:NCBI gene;Acc:100491173]) HSP 1 Score: 114.005 bits (284), Expect = 1.202e-25 Identity = 91/389 (23.39%), Postives = 174/389 (44.73%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQYF----ENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQ--CWNGAEITTGYKPNV 1346 ICP+ TCC + M+ ++ S+++ +S+ E + + R ++F++ L ++ +N MF++TY Y N D + +LK Y G N+E+IL+ F+ + E++ ++ + +E + C++ +L P+ ++ + + A AR V L +V +S K+ P+ C K YC +C L PC C +++ C + ++ W + A+ + ++ + PFN V + +KISEA++N+ + K+ C L+R R+ E + ++ E P T I+ L+ LV ++ K+K + +AIC + N+ CWNG + Y P + Sbjct: 58 ICPQEYTCCTSEMEDKLSQQSKLEFESLVEETSHFVRATFVSWHRKFDEFFRELLKNAEKSLNDMFVNTYGMLYMQNTEVFQDLFTELKRYYTGGNVNLEEILNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDIPRKLKVQVTRALIAARTFVQGLTVGREVANRVS-KISPNPGCIRALMKMLYCPYCRGLPSVRPCSNYCLNVMKGCLAN-----QADLDIEWNLFIDAMLLVVDRLEGPFNIESVMGPIDVKISEAIVNMQENSVQVSGKVFLGCGQPKSPPLLRLSRSFSENNNVRFHPYTAEERPTTAAITS-----LDRLVIEIKDKLKVSKKLWSSLPHAICKEVRITGENPNEDKCWNG-QTRARYLPEI 434
BLAST of glypican-1 vs. Ensembl Xenopus
Match: atf2 (activating transcription factor 2 [Source:Xenbase;Acc:XB-GENE-961088]) HSP 1 Score: 106.686 bits (265), Expect = 1.263e-23 Identity = 88/379 (23.22%), Postives = 170/379 (44.85%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMP-CDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKL-PKQGNQCWNGAEITTG-YKP 1340 ICP+ TCC + M+ +S+++ ++ SI LL R+ + ++Q+ L+ S+ + + F S Y Y N + D Y +L+ Y G N+E+ L F++ + E++ + + +E+ + CL + +L P+ + + + A+ AR V L AA DV +Q M S EC K YC C ++ C C +++ C + ++ W+ L+ +L +++K N + +H KISEA+ ++ + +K+ C K+ N +SE + K + + +++L++ + + D+ + + + C+ P ++CWNG IT G Y P Sbjct: 41 ICPQGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRNFDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRKANQVPM-STECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGCLAN-----QADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTP---KKTNKGSKSEER--RRKGKATQEDKSAVATMDNLISDVKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNG--ITKGRYMP 406
BLAST of glypican-1 vs. Ensembl Xenopus
Match: atf2 (activating transcription factor 2 [Source:Xenbase;Acc:XB-GENE-961088]) HSP 1 Score: 106.301 bits (264), Expect = 2.154e-23 Identity = 88/379 (23.22%), Postives = 170/379 (44.85%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMP-CDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKL-PKQGNQCWNGAEITTG-YKP 1340 ICP+ TCC + M+ +S+++ ++ SI LL R+ + ++Q+ L+ S+ + + F S Y Y N + D Y +L+ Y G N+E+ L F++ + E++ + + +E+ + CL + +L P+ + + + A+ AR V L AA DV +Q M S EC K YC C ++ C C +++ C + ++ W+ L+ +L +++K N + +H KISEA+ ++ + +K+ C K+ N +SE + K + + +++L++ + + D+ + + + C+ P ++CWNG IT G Y P Sbjct: 65 ICPQGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRNFDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRKANQVPM-STECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGCLAN-----QADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTP---KKTNKGSKSEER--RRKGKATQEDKSAVATMDNLISDVKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNG--ITKGRYMP 430
BLAST of glypican-1 vs. Ensembl Xenopus
Match: atf2 (activating transcription factor 2 [Source:Xenbase;Acc:XB-GENE-961088]) HSP 1 Score: 106.686 bits (265), Expect = 2.419e-23 Identity = 88/379 (23.22%), Postives = 171/379 (45.12%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMP-CDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKL-PKQGNQCWNGAEITTG-YKP 1340 ICP+ TCC + M+ +S+++ ++ SI LL R+ + ++Q+ L+ S+ + + F S Y Y N + D Y +L+ Y G N+E+ L F++ + E++ + + +E+ + CL + +L P+ + + + A+ AR V L AA DV +Q M S EC K YC C ++ C C +++ C + ++ W+ L+ +L +++K N + +H KISEA+ ++ + +K+ C K+ N +SE + + K + + +++L++ + + D+ + + + C+ P ++CWNG IT G Y P Sbjct: 72 ICPQGYTCCTSEMEENFANISRVEFEAKLRESSASIQRLLTTQHRNFDSYFQDLLNTSERVLQERFPSQYGDLYSQNSKIFRDLYSELRQYYRGSGINLEEALIEFWSRLLERVFKAQHTQYSFSEEYMDCLVKQYEQLKPFGDTPREVKLKAARAFIAARSFVQGLNAAADVVRKANQVPM-STECARAVMKLVYCPHCRGHSSIKLCSNYCWNVMRGCLAN-----QADLDSEWRNLIESLLLVADKFNGASNVENIVGAIHTKISEAITHMQENKELLTNKVFKICGTP---KKTNKGSKSEERRRKG--KATQEDKSAVATMDNLISDVKGILSDIQDYWVSLPSLFCTEKVTAGPGNEDKCWNG--ITKGRYMP 437
BLAST of glypican-1 vs. Ensembl Mouse
Match: Gpc1 (glypican 1 [Source:MGI Symbol;Acc:MGI:1194891]) HSP 1 Score: 114.005 bits (284), Expect = 8.275e-26 Identity = 87/381 (22.83%), Postives = 165/381 (43.31%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKL-PKQGNQCWNGAEITTG-YKPNV 1346 ICP+ TCC + M+ + S+M+L+S +++ L ++D +Q L+ S+ + + F + Y N R D Y +L+LY G ++E+ L F+ + E++ + + + CL L P+ + + + A+ AR V L A DV ++Q L P EC+ K YC+ C + PC C++++ C + ++ W+ LL ++ I++K P V +H+ ++EA+ + + ++ K+ C N + N + L+ +P L LV++ +++D+ + +CS + P ++CWNG I+ G Y P V Sbjct: 61 ICPQGYTCCTSEMEENLANHSRMELESALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQEAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLAP--ECSRAIMKLVYCAHCRGVPGARPCPDYCRNVLKGCLAN-----QADLDAEWRNLLDSMVLITDKFWGPSGAESVIGGVHVWLAEAINALQDNKDTLTAKVIQACGNPKV----NPHGSGPEEKRRRGKLALQ-EKPSTGTLEKLVSEAKAQLRDIQDFWISLPGTLCSEKMAMSPASDDRCWNG--ISKGRYLPEV 427
BLAST of glypican-1 vs. Ensembl Mouse
Match: Gpc6 (glypican 6 [Source:MGI Symbol;Acc:MGI:1346322]) HSP 1 Score: 112.464 bits (280), Expect = 2.903e-25 Identity = 67/289 (23.18%), Postives = 137/289 (47.40%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ICP+ TCC M+ ++ S+++ +++ E + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y G N+E++L+ F+ + E++ ++ + +E + C++ +L P+ +V + + A+ AR V L +V +S K+ P+ C K YC +C L PC+ C +++ C + ++ W + A+ ++ + + PFN V + + +KISEA+MN+ + K+ C Sbjct: 59 ICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVS-KVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLAN-----QADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGC 341
BLAST of glypican-1 vs. Ensembl Mouse
Match: Gpc6 (glypican 6 [Source:MGI Symbol;Acc:MGI:1346322]) HSP 1 Score: 112.464 bits (280), Expect = 2.903e-25 Identity = 67/289 (23.18%), Postives = 137/289 (47.40%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ICP+ TCC M+ ++ S+++ +++ E + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y G N+E++L+ F+ + E++ ++ + +E + C++ +L P+ +V + + A+ AR V L +V +S K+ P+ C K YC +C L PC+ C +++ C + ++ W + A+ ++ + + PFN V + + +KISEA+MN+ + K+ C Sbjct: 59 ICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVS-KVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLAN-----QADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGC 341
BLAST of glypican-1 vs. Ensembl Mouse
Match: Gpc6 (glypican 6 [Source:MGI Symbol;Acc:MGI:1346322]) HSP 1 Score: 112.079 bits (279), Expect = 3.208e-25 Identity = 67/289 (23.18%), Postives = 137/289 (47.40%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ICP+ TCC M+ ++ S+++ +++ E + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y G N+E++L+ F+ + E++ ++ + +E + C++ +L P+ +V + + A+ AR V L +V +S K+ P+ C K YC +C L PC+ C +++ C + ++ W + A+ ++ + + PFN V + + +KISEA+MN+ + K+ C Sbjct: 59 ICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVS-KVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLAN-----QADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGC 341
BLAST of glypican-1 vs. Ensembl Mouse
Match: Gpc4 (glypican 4 [Source:MGI Symbol;Acc:MGI:104902]) HSP 1 Score: 112.079 bits (279), Expect = 3.485e-25 Identity = 85/374 (22.73%), Postives = 160/374 (42.78%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKN-NAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQ--CWNG 1313 ICP+ TCC M+ + S+ K++ + + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y N+E++L+ F+ + E++ R+ + E + C++ +L P+ +V + + A+ AR L A DV +S + P+ +CT K YCS C L PC C +I+ C + ++ W + A+ ++ + + PFN V + + +KIS+A+MN+ + + K+ C R R+ E + S F + L+ LV + K+K + + +C+ N+ CWNG Sbjct: 59 ICPQDYTCCSQEMEEKYSLQSKDDFKTVVSEQCNHLQAIFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVAGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVARDVVSKVS-VVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLAN-----QGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPYHPEQRPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSTVCNDERMAAGNENEDDCWNG 426
BLAST of glypican-1 vs. UniProt/SwissProt
Match: sp|P50593|GPC1_CHICK (Glypican-1 OS=Gallus gallus OX=9031 GN=GPC1 PE=2 SV=1) HSP 1 Score: 120.168 bits (300), Expect = 5.137e-27 Identity = 94/390 (24.10%), Postives = 167/390 (42.82%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILR-MSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLI---------RKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICS-STFKLPKQGNQCWNGAEITTG-YKPNV 1346 ICP+ TCC + M+ S+ + +++ + +S+ +L + ++++Q+ L+ S+ + F S Y Y N + D Y +L+ Y G N+E+ L+ F+T + E++ + M+ E + C+ + P+ V + + A+ AR DV +SQ + S ECT K YC C + PC C +++ C + +N WK L+ AL ++++ P+N V +H++ISEA+ N+ SI K+ C N + +KRR TLE ++ + L LV + + + +CS P + ++CWNG +T G Y P V Sbjct: 58 ICPQGYTCCTSEMEENFANKSRSEFEAMMKEAGRSVQTILTAQYKSFDNYFQDLLNKSEKALYDTFPSLYGDLYTQNMKVFKDLYSELRRYYRGSNINLEEALNEFWTRLLERLFKLMNAQYHITDEYLDCMVKHAEQHKPFGEVPRDLKVKATRAFIVARSYAQGFLVGSDVVKKVSQVSL-SHECTRAVMKLMYCPHCRGMASVKPCSNYCLNVVKGCLAN-----QADLNTEWKYLMDALVAVADRIDGPYNVDTVIGTIHMRISEAISNLQENKVSITAKVFQGCGNPKVSMKGSSSEDKKRRGKV-------------TLE-AKSSAVALEMLVLDAKGNLTALKSYWVTLPGVLCSKKIMASPAEDDKCWNG--MTKGSYLPEV 425
BLAST of glypican-1 vs. UniProt/SwissProt
Match: sp|F1QCC6|GPC1_DANRE (Glypican-1 OS=Danio rerio OX=7955 GN=gpc1 PE=2 SV=1) HSP 1 Score: 115.161 bits (287), Expect = 2.603e-25 Identity = 95/398 (23.87%), Postives = 178/398 (44.72%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFL--------KLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVH---NFYTS-----IRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKT---LEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEIT-TGYKPNV 1346 ICP+ TCC +AM+ + +S+ + + + +SI LL R + ++ L+ S+ + + F++ Y+ N D Y +L Y G N+E+ LD F+ ++ E++L+ S + E L++ FL L P+ + + + + A+ AR V L AA ++ +SQ + S EC K YC C L PC CK+++ C + ++ W++L+ + ++++ + V ++ ++ISEAV+ + YTS D+ + + + + + E + ++ PK+ LE+ V + +K+K+M L+ +A+CS G++CWNG IT Y P V Sbjct: 58 ICPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQALLNAQYRTFDTYFLELLNGSERWLEEAFVAALGELYRLNAGVFRDLYAELHRYYSGASLNLEEALDEFWMKLLERLLKAS-----DPETASLLSDDFLDCASKQTETLRPFGDAPRELKAKLVRAFIAARAFVQGLNAAGEIVRKVSQVPL-SPECNRAIMKLVYCPHCRGLGSVKPCINYCKNVMKGCLAN-----QADLDTEWQSLIETMLQVASSFGAEPSMDTVIYSIPVRISEAVLAMQENMEIYTSKVFKACGDRGEEGTPSSISEEPKKKERTVTALEYKPSPKSAARLEVQ----------VTDVYSKLKEMQLYWIQLPSALCSGKTASSTTGDKCWNG--ITKASYLPEV 432
BLAST of glypican-1 vs. UniProt/SwissProt
Match: sp|Q9QZF2|GPC1_MOUSE (Glypican-1 OS=Mus musculus OX=10090 GN=Gpc1 PE=1 SV=1) HSP 1 Score: 114.005 bits (284), Expect = 5.788e-25 Identity = 87/381 (22.83%), Postives = 165/381 (43.31%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKL-PKQGNQCWNGAEITTG-YKPNV 1346 ICP+ TCC + M+ + S+M+L+S +++ L ++D +Q L+ S+ + + F + Y N R D Y +L+LY G ++E+ L F+ + E++ + + + CL L P+ + + + A+ AR V L A DV ++Q L P EC+ K YC+ C + PC C++++ C + ++ W+ LL ++ I++K P V +H+ ++EA+ + + ++ K+ C N + N + L+ +P L LV++ +++D+ + +CS + P ++CWNG I+ G Y P V Sbjct: 61 ICPQGYTCCTSEMEENLANHSRMELESALHDSSRALQATLATQLHGIDDHFQRLLNDSERTLQEAFPGAFGDLYTQNTRAFRDLYAELRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLPDDYLDCLGKQAEALRPFGDAPRELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLAP--ECSRAIMKLVYCAHCRGVPGARPCPDYCRNVLKGCLAN-----QADLDAEWRNLLDSMVLITDKFWGPSGAESVIGGVHVWLAEAINALQDNKDTLTAKVIQACGNPKV----NPHGSGPEEKRRRGKLALQ-EKPSTGTLEKLVSEAKAQLRDIQDFWISLPGTLCSEKMAMSPASDDRCWNG--ISKGRYLPEV 427
BLAST of glypican-1 vs. UniProt/SwissProt
Match: sp|O75487|GPC4_HUMAN (Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4) HSP 1 Score: 113.62 bits (283), Expect = 7.791e-25 Identity = 87/374 (23.26%), Postives = 162/374 (43.32%), Query Frame = 3 Query: 219 ICPK-TTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKN-NAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQ--CWNG 1313 ICP+ +TCC M+ + S+ KS+ + + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y N+E++L+ F+ + E++ R+ + E + C++ +L P+ +V + + A+ AR L A DV +S + P+ +CT K YCS C L PC C +I+ C + ++ W + A+ ++ + + PFN V + + +KIS+A+MN+ + + K+ C R R+ E + S F + L+ LV + K+K + + +C+ GN+ CWNG Sbjct: 59 ICPQGSTCCSQEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTYGHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLECVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVS-VVNPTAQCTHALLKMIYCSHCRGLVTVKPCYNYCSNIMRGCLAN-----QGDLDFEWNNFIDAMLMVAERLEGPFNIESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPHHPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNG 426
BLAST of glypican-1 vs. UniProt/SwissProt
Match: sp|Q9R087|GPC6_MOUSE (Glypican-6 OS=Mus musculus OX=10090 GN=Gpc6 PE=1 SV=1) HSP 1 Score: 112.464 bits (280), Expect = 2.031e-24 Identity = 67/289 (23.18%), Postives = 137/289 (47.40%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ICP+ TCC M+ ++ S+++ +++ E + + + ++F++ L+ ++ +N MF+ TY Y N D + +LK Y G N+E++L+ F+ + E++ ++ + +E + C++ +L P+ +V + + A+ AR V L +V +S K+ P+ C K YC +C L PC+ C +++ C + ++ W + A+ ++ + + PFN V + + +KISEA+MN+ + K+ C Sbjct: 59 ICPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVS-KVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLAN-----QADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGC 341
BLAST of glypican-1 vs. TrEMBL
Match: I1ZI58 (Glypican-1 OS=Schmidtea mediterranea OX=79327 PE=2 SV=1) HSP 1 Score: 1456.43 bits (3769), Expect = 0.000e+0 Identity = 749/751 (99.73%), Postives = 751/751 (100.00%), Query Frame = 3 Query: 45 MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLXXXXXXXXXXXXXXGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTPKPSEPRTPQIEGSGSLDTVEXXXXXXXXXXXXXXXXVVPFVMTDLVKSPKSGRPDDESSLVEGSGQEEVTPRKPHEFNSRVEHETTTSAPVDLTTPSVLLPNDLPGEIPPEIWIPRVIDYDSRGPILNNPNSTCSITKFHPAMFFSLFVIYILL 2297 MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNSEEESESQYFE+VPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLPTIEPINEPKEIIEGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTPKP+EPRTPQIEGSGSLDTVEKSTETSKIFTTKTSTTVVPFVMTDLVKSPKSGRPDDESSLVEGSGQEEVTPRKPHEFNSRVEHETTTSAPVDLTTPSVLLPNDLPGEIPPEIWIPRVIDYDSRGPILNNPNSTCSITKFHPAMFFSLFVIYILL Sbjct: 1 MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNSEEESESQYFESVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLPTIEPINEPKEIIEGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTPKPAEPRTPQIEGSGSLDTVEKSTETSKIFTTKTSTTVVPFVMTDLVKSPKSGRPDDESSLVEGSGQEEVTPRKPHEFNSRVEHETTTSAPVDLTTPSVLLPNDLPGEIPPEIWIPRVIDYDSRGPILNNPNSTCSITKFHPAMFFSLFVIYILL 751
BLAST of glypican-1 vs. TrEMBL
Match: A0A0X3PZ77 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR151712 PE=3 SV=1) HSP 1 Score: 162.54 bits (410), Expect = 3.725e-37 Identity = 96/390 (24.62%), Postives = 179/390 (45.90%), Query Frame = 3 Query: 69 LIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICP---KTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRM-------------------------------------SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCS-WCSLTETMP-----------CDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN 1082 + + L AL+ A + +DC + W + +YQ S +CP +CCD+ M+ I VS+ +L + L++I + + N+ LN +++++L ++++++ F + Y Y+ N+ F + + L YM GK ++ +LD FF+++ I+ + + L ++++I+CL+N K NP+ VD + S F EAYP ARMLVNSL A + + +++ EC +A+ +C +C E P C G C ++ CF M ++ AW L+ ++ + + + + FNF VN NLH+ +SEA+ V Y+ ++ ++ C++ Sbjct: 13 VFLVFLSALYLFPLAVSGLDCARARRDWLTVQYQVLLGSRPIPMSSPPQQVCPTLGAQSCCDSNMEQNIYAVSERQLSAAMTKWLETISQQMENDCVSLNYYFRSDLKEARERLHTSFSTIYGLMYQRNRDFFYRLFADLDDYMAGKRGQLKNLLDEFFSQLRTSIVGLMETTALGGGSGGGGGGTTGGNTGHPMGGGAAAAAGSATGLRTQDSKRIQCLSNGLNKQNPFDGVDTRLQSRFLEAYPPARMLVNSLAAGSALVKSILREVSGRPECIIAFARLHHCGPYCLAREPPPSHAVPTQALDLCAGACSNLASVCFFEGKNSRMPQLADAWVQLIDSISQATTRLERSFNFPGVNKNLHIYLSEAITYVQQKYSQVKTQIDRECDS 402
BLAST of glypican-1 vs. TrEMBL
Match: U6JA45 (Glypican OS=Echinococcus granulosus OX=6210 GN=EGR_06051 PE=3 SV=1) HSP 1 Score: 154.066 bits (388), Expect = 2.093e-34 Identity = 89/350 (25.43%), Postives = 173/350 (49.43%), Query Frame = 3 Query: 66 LLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQY-SDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKIL----RMSILSKNNA----EKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYC-SWCSL---TETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 L + L L N + + +DC K W +++Y+ + + + + S+T+ I T+CCD M+ +I V + +L + L + E + ++S L+ F++++L +++++++ F Y +YK N F F F++ L+ YM G+ ++ +++ +FF ++ I+ + + + + A ++I CL+ + K N + D + F + YP ARMLVNSL AA + + + EC +++ YC ++C T C C + I CF + + W L+ A+ + + + NF VN +LH+ +SEA+ VH Y +++ L C Sbjct: 17 FLFLISLALLTWNAFSVSGLDCTKAKRDWLNYRYKVLTTNAISPSYSQTICPIIESTSCCDKQMEMDIYTVGESELPTSLANWLAPVAEQMESDSLALDYFFRSDLMEARNRLHEAFSGIYGYNYKVNHAFFFQFFNDLEAYMAGRRGDLAQLVTSFFNQLRTSIVVLMEKAEVATGSTATPDYQRINCLSEALGKQNAFDLTDVHLREQFLQVYPPARMLVNSLAAASKLLRTIVEDASKRPECIVAFSRIHYCGTYCGAREGTHAKVCPAACDNFIKTCFADASSDSSKSLPHVWSKLITAITVTTKRLERTQNFASVNKDLHIFLSEAITYVHQKYATVKPSLIQEC 366
BLAST of glypican-1 vs. TrEMBL
Match: A0A087W1I7 (Glypican OS=Echinococcus multilocularis OX=6211 GN=EmuJ_000241300 PE=3 SV=1) HSP 1 Score: 150.984 bits (380), Expect = 1.955e-33 Identity = 86/350 (24.57%), Postives = 175/350 (50.00%), Query Frame = 3 Query: 66 LLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQY-SDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKIL----RMSILSKN----NAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYC-SWCSL---TETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 L + L L + + + +DC K W +++Y+ + + + + S+ + I T+CCD M+ +I V + +L + L + E + ++S L+ F++++L +++++++ F Y +YK N F F F++ L+ YM G+ ++ +++ +FF ++ I+ + + + + ++++I CL+ + K N + + D + F + YP ARMLVNSL AA + + + EC +++ YC ++C T+ C C + I CF + + W L+ A+ + + + NF VN +LH+ +SEA+ VH Y +++ L C Sbjct: 17 FLFLISLALLSWDAFSVSGLDCTKAKRDWLNYRYKVLTTNAISPSYSQPICPIIESTSCCDKQMEMDIYTVGESELPTSLANWLVPVAEQMESDSLALDYFFRSDLMEARNRLHEAFSGIYGYNYKVNHAFFFQFFNDLEAYMAGRRGDLAQLVTSFFNQLRTSIVVLMEKAEVATGSTVTPDSQRINCLSEALGKQNAFDHTDVHLREQFLQVYPPARMLVNSLAAASKLLRTIVEDASKRPECIVAFSRIRYCGTYCGAREGTQAKVCPAACDNFIKTCFVDASSDSSKSLPHVWSKLITAITVTTKRLERTQNFASVNKDLHIFLSEAITYVHQKYATVKPSLIQEC 366
BLAST of glypican-1 vs. TrEMBL
Match: C1LFG9 (Glypican-4 OS=Schistosoma japonicum OX=6182 GN=Xgly4 PE=2 SV=1) HSP 1 Score: 142.124 bits (357), Expect = 1.100e-30 Identity = 94/382 (24.61%), Postives = 175/382 (45.81%), Query Frame = 3 Query: 39 KIMNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICP--KTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRM-----SILS--------------KNNA------------EKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC---SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ++M + LLI+T++ + + +DC + K +W +Y L T + ICP T+CCD M+ E+ V Q +L L+ + + N+S L +Q +L +K ++++ F Y +YK ++ F F F+ L+ YM G+ + ++ FF ++ + I+ + ++S NN+ +IRCL++ +L+P+ +VD + + EAYP ARMLVN L + L +++ +C + +C+ C SL+ C C ++ C E ++ W L+ + +N+ + FNF VN NL ++ISEA+ ++ Y+ + K ++ C Sbjct: 5 EVMRIFRSILLIMTLVTSTYA-------LDCTSFKQQWMKIRYTMLKGLHSSTINGPTSNICPVTGTSCCDVNMEREMYSVGQRQLIKQCNSWLQ-VARKMSNDSAILESIFQADLQQAKGRLHQFFSRIYGYNYKLHRNFFFGFFTDLEQYMAGQRGQLGVLIKNFFNQLRDSIVSLIEKSGQVISNPPFGSAPSNAGSFGNNSPGIEGTDEASESRRIRCLSDKIAQLHPFDDVDVRLHARMLEAYPPARMLVNVLSVTSKLLHHLVDQVVAQSQCILGITRYRFCALCEAQSLSNV--CPDSCAQLLSSCLHGDGPDEA-QLAYIWPQLIDTIVVATNRLERSFNFPAVNRNLQMEISEAITSLQTRYSETKSKFESEC 375
BLAST of glypican-1 vs. Ensembl Cavefish
Match: gpc6a (glypican 6a [Source:ZFIN;Acc:ZDB-GENE-071004-15]) HSP 1 Score: 111.309 bits (277), Expect = 3.995e-25 Identity = 81/371 (21.83%), Postives = 164/371 (44.20%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILR-MSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN----KLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWN 1310 +C + TCC + M+ ++ S++KL+ + E + ++ + ++F+ LD S+ +N MF+ TY Y N D + +LK Y G N+E++L+ F++ + E++ + ++ + + C++ +L P+ ++ + + + A+ AR V L +V +S K+ S C+ + YC +C L PC C++++ C + ++ W + A+ ++ + + PFN V + +KISEA+M + + + K+ C + L R R E+ + F + L+ LV + +K +A+CS ++ QCWN Sbjct: 32 VCARGQTCCSSEMEDKLGVQSKVKLEGMVEESSDVLRSTFFSRHKKFDEFFLELLDNSEKSLNDMFVRTYGKLYTHNSEIFEDLFSELKRYYTGGNVNLEEMLNDFWSRLLERMFQLLNSQYTFTDDYLECISKYTDQLKPFGDIPRKLKAQVTRAFIAARTFVQGLMVGREVANRVS-KVNVSPGCSKALTRMLYCPYCGGLPGLRPCGNYCQNVMKGCLAN-----QADLDPEWNLFIDAMLLVAERLEGPFNIEAVMEPIDVKISEAIMTMQDNSMQVSAKVFQGCGHPKPAGLSRTSRGISEKGFNTRFRPYSPEERPTTAAGTSLDRLVIDIKETLKKSKKFWSTLPDAVCSRE-RVSDDDEQCWN 395
BLAST of glypican-1 vs. Ensembl Cavefish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367]) HSP 1 Score: 98.9821 bits (245), Expect = 3.547e-21 Identity = 85/374 (22.73%), Postives = 163/374 (43.58%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMS---ILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEI--SQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGN-QCWNG 1313 +CP+ TCC +AM+ + +S+ + + + +SI L R + ++ L+ S+ + + F+ + Y N D Y +L+ Y G N+E+ LD F+ + E++L+ S S + + + C + L + + + + + AR V L A DV +SQ L P EC K YC C L PC CK+++ C + ++ W+ L+ + ++++ + + +++ ++ISEAV ++ +KL C + + + E + E+ TLE S + L V+ + +K+K+M + +A+C+S N +CWNG Sbjct: 27 VCPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQATLNAQYRSFDTYFIELLNGSERWLEEAFVKALGALYGPNAVVFRDLYSELRRYYRGAALNLEEALDEFWARLLERMLKASDPAAASLISDDFLECASKQAETLRLFGEAPRELKTRLVRVFVAARAFVQGLNMAGDVVRKVSQVPLTP--ECNRAIMKLVYCPHCRGLGSVKPCANYCKNVMKGCLAN-----QADLDTEWQNLIDTMLQVASSFGTEPSMDVILHSIPVRISEAVQHMQENMELYTNKLFQACGER-GEEGTPTSVSEEPKKKESTVTTLEYKPSSAAAVRLEVQVSDVSSKLKEMQMFWIQLASALCNSKAASGSSNNDKCWNG 392
BLAST of glypican-1 vs. Ensembl Cavefish
Match: gpc4 (glypican-4 [Source:NCBI gene;Acc:103025650]) HSP 1 Score: 98.9821 bits (245), Expect = 3.867e-21 Identity = 83/407 (20.39%), Postives = 169/407 (41.52%), Query Frame = 3 Query: 114 QNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYM--DGKEQNIEKILDTFFTEMAEKILRM-SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETM-PCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN--KLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNG 1313 Q +C ++T + S + +D K + V CP+ +CC M+ ++ S+ LK+ ++ + + F++ L ++ ++ MF+ TY Y N F+ +L+ Y G +++ +L F+ E+ E++ R+ ++ + + C++ +L P+ +V + + A+ AR L DV +S + S C K YC +CS + PC C +++ C + ++ W L A+ ++ + + PFNF V + + +KIS+A+MN+ + K+ C + R +R++++ F + ++ LV + K+K + +C Q + CWNG Sbjct: 24 QKSKNCNEVRTAYSSKGFNINDVPNKGVQGAHLKV-CPQGFSCCTLEMEEKLSQQSRTDLKAPVSQLSSTLQSTFTQRHQHFDQFFKELLTNAEKSLHDMFVRTYGVMYVKNAELFKHFFHELRRYYASGGAAVHLDSMLSEFWAELLERMFRLVNVQYEFTDGYMECVSRHTDQLKPFGDVPRKLKLQLTRAFVAARTFTLGLALIPDVVSKVS-TVSASPSCVRAAMKMLYCPYCSGQVALKPCKNYCLNVMRGCLAN-----QADLDTEWNNFLDAMLSLAERLEGPFNFESVMDPIDVKISDAIMNMQENSMQVSQKVFQGCGQPKPMYRSKRSTKDSGFPGRFRPYSPDTRPTTAAGTNMDRLVTDVKKKLKHAKKFWSTLPDTVCVG--DRVAQADDCWNG 421
BLAST of glypican-1 vs. Ensembl Cavefish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367]) HSP 1 Score: 98.9821 bits (245), Expect = 4.460e-21 Identity = 85/374 (22.73%), Postives = 163/374 (43.58%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMS---ILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEI--SQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGN-QCWNG 1313 +CP+ TCC +AM+ + +S+ + + + +SI L R + ++ L+ S+ + + F+ + Y N D Y +L+ Y G N+E+ LD F+ + E++L+ S S + + + C + L + + + + + AR V L A DV +SQ L P EC K YC C L PC CK+++ C + ++ W+ L+ + ++++ + + +++ ++ISEAV ++ +KL C + + + E + E+ TLE S + L V+ + +K+K+M + +A+C+S N +CWNG Sbjct: 27 VCPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQATLNAQYRSFDTYFIELLNGSERWLEEAFVKALGALYGPNAVVFRDLYSELRRYYRGAALNLEEALDEFWARLLERMLKASDPAAASLISDDFLECASKQAETLRLFGEAPRELKTRLVRVFVAARAFVQGLNMAGDVVRKVSQVPLTP--ECNRAIMKLVYCPHCRGLGSVKPCANYCKNVMKGCLAN-----QADLDTEWQNLIDTMLQVASSFGTEPSMDVILHSIPVRISEAVQHMQENMELYTNKLFQACGER-GEEGTPTSVSEEPKKKESTVTTLEYKPSSAAAVRLEVQVSDVSSKLKEMQMFWIQLASALCNSKAASGSSNNDKCWNG 392
BLAST of glypican-1 vs. Ensembl Cavefish
Match: gpc1a (glypican 1a [Source:NCBI gene;Acc:553367]) HSP 1 Score: 98.5969 bits (244), Expect = 5.185e-21 Identity = 85/374 (22.73%), Postives = 163/374 (43.58%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMS---ILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQ-KLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEI--SQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGN-QCWNG 1313 +CP+ TCC +AM+ + +S+ + + + +SI L R + ++ L+ S+ + + F+ + Y N D Y +L+ Y G N+E+ LD F+ + E++L+ S S + + + C + L + + + + + AR V L A DV +SQ L P EC K YC C L PC CK+++ C + ++ W+ L+ + ++++ + + +++ ++ISEAV ++ +KL C + + + E + E+ TLE S + L V+ + +K+K+M + +A+C+S N +CWNG Sbjct: 55 VCPQGYTCCTSAMEETLSNLSRREFEGLVREAGRSIQATLNAQYRSFDTYFIELLNGSERWLEEAFVKALGALYGPNAVVFRDLYSELRRYYRGAALNLEEALDEFWARLLERMLKASDPAAASLISDDFLECASKQAETLRLFGEAPRELKTRLVRVFVAARAFVQGLNMAGDVVRKVSQVPLTP--ECNRAIMKLVYCPHCRGLGSVKPCANYCKNVMKGCLAN-----QADLDTEWQNLIDTMLQVASSFGTEPSMDVILHSIPVRISEAVQHMQENMELYTNKLFQACGER-GEEGTPTSVSEEPKKKESTVTTLEYKPSSAAAVRLEVQVSDVSSKLKEMQMFWIQLASALCNSKAASGSSNNDKCWNG 420
BLAST of glypican-1 vs. Ensembl Medaka
Match: gpc2 (glypican 2 [Source:NCBI gene;Acc:101173153]) HSP 1 Score: 114.005 bits (284), Expect = 6.763e-26 Identity = 89/388 (22.94%), Postives = 171/388 (44.07%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMK--LKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCE----NKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQ---GNQCWNGAEITTGYKPNV 1346 +CP+ TCC + M+ E LG+ + LK+I E + + + R ++F++ +D+S+ MN+MF TY + N + + +L+ Y G ++ ++L F++ + E++ + +E + C++ +L P+ ++ + + A+ AR L L D+ ++ + KL EC + +YC C + PC LC +++ C + ++ W + AL +S K + PFN ++ +K+SEA+M + S+ K+ C + KR E + F + + L+ LV +L +++ MT + IC+ KL +CWNG + Y P+V Sbjct: 67 LCPQDYTCCSSQME-ETLGLQSERDFLKAIEE-NSQFLQTTFTQRHRRFDEFFRELIDLSEKSMNQMFTKTYGLLFTQNAHIFQELFVELRRYYSGSSVSLAEVLSDFWSRLVERVFSLVNPQYQFSEDYLECVSKHAEQLQPFGDMPRKLRVQVSRAFIAARSLSQGLATGRDI-VNKATKLTADPECVRGLMRQWYCPLCRGVPYLQPCHPLCLNVMKGCLAN-----QADLDTEWNNFIDALYLVSEKLEGPFNMELAAESIAVKVSEAIMYMQENSVSVSSKVFQGCGAPKPSPARSKRSPKESGGSRRPFRTYTPEEKPTTAAGTNLDRLVTELKERLRPMTGFWVSLPQTICNDE-KLAADVTNSERCWNG-QTRGRYLPDV 444
BLAST of glypican-1 vs. Ensembl Medaka
Match: gpc2 (glypican 2 [Source:NCBI gene;Acc:101173153]) HSP 1 Score: 114.005 bits (284), Expect = 6.763e-26 Identity = 89/388 (22.94%), Postives = 171/388 (44.07%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMK--LKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEK-IRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCE----NKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQ---GNQCWNGAEITTGYKPNV 1346 +CP+ TCC + M+ E LG+ + LK+I E + + + R ++F++ +D+S+ MN+MF TY + N + + +L+ Y G ++ ++L F++ + E++ + +E + C++ +L P+ ++ + + A+ AR L L D+ ++ + KL EC + +YC C + PC LC +++ C + ++ W + AL +S K + PFN ++ +K+SEA+M + S+ K+ C + KR E + F + + L+ LV +L +++ MT + IC+ KL +CWNG + Y P+V Sbjct: 67 LCPQDYTCCSSQME-ETLGLQSERDFLKAIEE-NSQFLQTTFTQRHRRFDEFFRELIDLSEKSMNQMFTKTYGLLFTQNAHIFQELFVELRRYYSGSSVSLAEVLSDFWSRLVERVFSLVNPQYQFSEDYLECVSKHAEQLQPFGDMPRKLRVQVSRAFIAARSLSQGLATGRDI-VNKATKLTADPECVRGLMRQWYCPLCRGVPYLQPCHPLCLNVMKGCLAN-----QADLDTEWNNFIDALYLVSEKLEGPFNMELAAESIAVKVSEAIMYMQENSVSVSSKVFQGCGAPKPSPARSKRSPKESGGSRRPFRTYTPEEKPTTAAGTNLDRLVTELKERLRPMTGFWVSLPQTICNDE-KLAADVTNSERCWNG-QTRGRYLPDV 444
BLAST of glypican-1 vs. Ensembl Medaka
Match: gpc4 (glypican-6 [Source:NCBI gene;Acc:101160491]) HSP 1 Score: 113.235 bits (282), Expect = 1.191e-25 Identity = 103/485 (21.24%), Postives = 219/485 (45.15%), Query Frame = 3 Query: 42 IMNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKT-TCCDNAMKTEILGVSQMKLK---SIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKL-KLYMDGKEQ-NIEKILDTFFTEMAEKILRM-SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETM-PCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCE----NKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAE--------ITTGYKPNVKEKDANKNL-KISPLVKTSIATLQKITAAL 1433 ++ L + C L + + E Q +C ++ + S + +D K + ++ V CP+ +CC M+ ++ S ++K S +L++I + +N+ ++F++ L ++ ++ MFL TY Y+ N +F+ L + Y+DG + +++ +L F+ ++ E++ R+ ++ + + + C++ + +L P+ +V + + K A+ AR V L+ +VF +S + + C K YC +CS + PC C +++ C + ++ W L A+ ++++ + PFNF V + + +KISEA+MN+ + K+ C ++ R +R+ +E + F + L+ L +++ K+K +C+ P G++CWNG I G D ++ K ++++ IA L+++T L Sbjct: 4 LLVLCVVCPLAVLCVSGTAE----QKSKNCNEVRAAFSSKGFNINDVPNKGISGASLKV-CPQGFSCCTVEMEEKLSQQSHTEIKAPVSRLSTNLQTIFKERHNH---FDNFFRELLKNAEASLHNMFLRTYGKMYEQNSELFGNFFASLTRYYIDGSAKVDLDAMLTDFWADLLERMFRLVNVQFEFSDAYMECVSRNTDELQPFGDVPRKLRIQLKRAFIAARTFVRGLKLMPEVFNKVS-TVSATPSCVRAATKMLYCPYCSGQVALKPCQNYCLNVMRGCLAN-----QADLDTEWNNFLDAMLNLADRLEGPFNFESVMDPIDVKISEAIMNMQENSMQVSQKVFQGCGTPKLSQSFRSKRSLKETGFTGRFRPYTPEARPTTAAGTSLDRLTSEVKKKLKHAKKFWSTLPETVCADERIAP--GDECWNGTAKSRYELHVIGNGLANQGTNPDVEVDITKPHTVIRSQIAALKEMTIWL 472
BLAST of glypican-1 vs. Ensembl Medaka
Match: gpc4 (glypican-6 [Source:NCBI gene;Acc:101160491]) HSP 1 Score: 106.301 bits (264), Expect = 1.711e-23 Identity = 79/353 (22.38%), Postives = 170/353 (48.16%), Query Frame = 3 Query: 42 IMNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKT-TCCDNAMKTEILGVSQMKLK---SIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKL-KLYMDGKEQ-NIEKILDTFFTEMAEKILRM-SILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETM-PCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANC 1076 ++ L + C L + + E Q +C ++ + S + +D K + ++ V CP+ +CC M+ ++ S ++K S +L++I + +N+ ++F++ L ++ ++ MFL TY Y+ N +F+ L + Y+DG + +++ +L F+ ++ E++ R+ ++ + + + C++ + +L P+ +V + + K A+ AR V L+ +VF +S + + C K YC +CS + PC C +++ C + ++ W L A+ ++++ + PFNF V + + +KISEA+MN+ + K+ C Sbjct: 4 LLVLCVVCPLAVLCVSGTAE----QKSKNCNEVRAAFSSKGFNINDVPNKGISGASLKV-CPQGFSCCTVEMEEKLSQQSHTEIKAPVSRLSTNLQTIFKERHNH---FDNFFRELLKNAEASLHNMFLRTYGKMYEQNSELFGNFFASLTRYYIDGSAKVDLDAMLTDFWADLLERMFRLVNVQFEFSDAYMECVSRNTDELQPFGDVPRKLRIQLKRAFIAARTFVRGLKLMPEVFNKVS-TVSATPSCVRAATKMLYCPYCSGQVALKPCQNYCLNVMRGCLAN-----QADLDTEWNNFLDAMLNLADRLEGPFNFESVMDPIDVKISEAIMNMQENSMQVSQKVFQGC 342
BLAST of glypican-1 vs. Ensembl Medaka
Match: gpc6a (glypican-6 [Source:NCBI gene;Acc:101172317]) HSP 1 Score: 97.8265 bits (242), Expect = 1.080e-20 Identity = 89/423 (21.04%), Postives = 179/423 (42.32%), Query Frame = 3 Query: 219 ICPKT-TCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILR-MSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWC-SLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCE----NKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANK------NLKIS---PLVKTSIATLQKITAALNN 1439 +CP+ TCC + M+ ++ S+++ +++ E + + + + ++F+ LD S+ +N +F TY Y N D + +LK Y G N+E++L+ F++ + E++ + ++ + + C+ L P+ + + + +A+ AR V L +V + K+ + C K YC +C + PC C +++ C + ++ W + A+ ++N+ + P N V + + +KISEA++ + + K+ C + L R R + S++ P+ S L LVN + ++++ N ICS QCWN + VKE N+ ++ I+ L++ I L+ +T L N Sbjct: 59 VCPQGYTCCTSEMEEKLNQQSKLEFENMVEESSRQMRTTFISRHKKFDEFFLELLDNSEKSLNSLFTRTYGKLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWSRLLERMFQLLNSQYHFTDDYLECIGKIADVLKPFGDAPRRLKIQVTKAFIAARTFVQGLMVGREV-ANRVAKVNVAPACVRALTKMLYCPYCRGMAGLKPCHNYCHNVMRGCLAN-----QADLDSEWNLFIDAMLLVANRLEGPDNIEAVIDPVDIKISEAIITMQENSMQVSAKVFQECGQPKPSGLSRSTRG-IDMLNSRFRPYTPEQRPTSAAGTS-LERLVNDIKERLEESKRVWSKLPNDICSKEKLTQPDEEQCWNSHTKGRYFPEVVKEGLTNQINNPEVDVDITRPDTLIRQQIMALRVMTNKLKN 473
BLAST of glypican-1 vs. Planmine SMEST
Match: SMESG000052359.1 (SMESG000052359.1) HSP 1 Score: 1455.27 bits (3766), Expect = 0.000e+0 Identity = 748/751 (99.60%), Postives = 749/751 (99.73%), Query Frame = 3 Query: 45 MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNXXXXXXXQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLXXXXXXXXXXXXXXGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTPKPSEPRTPQIEGSGSLDTVEXXXXXXXXXXXXXXXXVVPFVMTDLVKSPKSGRPDDESSLVEGSGQEEVTPRKPHEFNSRVEHETTTSAPVDLTTPSVLLPNDLPGEIPPEIWIPRVIDYDSRGPILNNPNSTCSITKFHPAMFFSLFVIYILL 2297 MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNSEEESESQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKN ICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLPTIEPI EPKEIIEGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTPKP+EPRTPQIEGSGSLDTVEKSTETSKIFTTKTSTTVVPFVMTDLVKSPKSGRPDDESSLVEGSGQEEVTPRKPHEFNSRVEHETTTSAPVDLTTPSVLLPNDLPGEIPPEIWIPRVIDYDSRGPILNNPNSTCSITKFHPAMFFSLFVIYILL Sbjct: 1 MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICPKTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCENKLIRKRRNSEEESESQYFENVPKTLEISQPKPILLNDLVNKLLTKMKDMTLHLQNYKNTICSSTFKLPKQGNQCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIKFVEKPKITEIPRLRPSRISEQMEGSGKGGVDIENTSNKSKPKLPTIEPIKEPKEIIEGSGEIKTPSNEISKNRPAFPQLPPNNINTPKPGKITKSPPIPDDEDLPTDQNENKNEKTPKPAEPRTPQIEGSGSLDTVEKSTETSKIFTTKTSTTVVPFVMTDLVKSPKSGRPDDESSLVEGSGQEEVTPRKPHEFNSRVEHETTTSAPVDLTTPSVLLPNDLPGEIPPEIWIPRVIDYDSRGPILNNPNSTCSITKFHPAMFFSLFVIYILL 751
BLAST of glypican-1 vs. Planmine SMEST
Match: SMESG000032627.1 (SMESG000032627.1) HSP 1 Score: 243.432 bits (620), Expect = 3.704e-68 Identity = 160/536 (29.85%), Postives = 273/536 (50.93%), Query Frame = 3 Query: 72 IITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICP---KTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN---KLIRKRRNXXXXXXXQ--------YFE---NVPKTLEISQPKPI-----LLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGN-----QCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIK----FVEKPKITEIPRLRPSRISEQMEGSGKGGVDIEN 1586 I + F L + + + +C WYS KY Y + L + T CP CC++ + E+ VS++KLK AE L++++ + N+S L + Y N+L+ +K+ +N++F +TY +YK + F F ++DKLK+YM+GK+ NI ++LD FF EMA KI+++ I +++ E +C + ++ PYQ D ++ N +Y +RM VN++ D F L K+ PS C ++ F+C C+ C CKS++ CFGSF E+ K++K + L AL +++NK + NF VN+ ++++IS A+MN+ N Y +I+++++A C+N K+ RKR+ ++E Q ++E N +S+ P+ LND ++ + ++K L+ Y L Q N QCWNG G + K +S + KT L+ IT +N++L +V DP+ ++ + KP + ++ +EGSG D EN Sbjct: 6 FIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTA-FNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWEKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGT--LPGIVTDKNNKKKLDKSSVS-VFKTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSG----DFEN 533
BLAST of glypican-1 vs. Planmine SMEST
Match: SMESG000032627.1 (SMESG000032627.1) HSP 1 Score: 243.432 bits (620), Expect = 3.877e-68 Identity = 160/536 (29.85%), Postives = 273/536 (50.93%), Query Frame = 3 Query: 72 IITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFTTSKTVDVICP---KTTCCDNAMKTEILGVSQMKLKSIAEIHLKSIIELLYNNSRDLNDFYQNNLDISKDQMNKMFLSTYASSYKDNQRFLFDFYDKLKLYMDGKEQNIEKILDTFFTEMAEKILRMSILSKNNAEKIRCLTNSFLKLNPYQNVDKAIVSNFKEAYPTARMLVNSLRAAHDVFLDLSQKLMPSIECTTKYAKAFYCSWCSLTETMPCDGLCKSIIGKCFGSFNRKEMNKINKAWKALLGALEKISNKAKHPFNFVEVNNNLHLKISEAVMNVHNFYTSIRDKLQANCEN---KLIRKRRNXXXXXXXQ--------YFE---NVPKTLEISQPKPI-----LLNDLVNKLLTKMKDMTLHLQNYKNAICSSTFKLPKQGN-----QCWNGAEITTGYKPNVKEKDANKNLKISPLVKTSIATLQKITAALNNILSKQVVDPDAFKIK----FVEKPKITEIPRLRPSRISEQMEGSGKGGVDIEN 1586 I + F L + + + +C WYS KY Y + L + T CP CC++ + E+ VS++KLK AE L++++ + N+S L + Y N+L+ +K+ +N++F +TY +YK + F F ++DKLK+YM+GK+ NI ++LD FF EMA KI+++ I +++ E +C + ++ PYQ D ++ N +Y +RM VN++ D F L K+ PS C ++ F+C C+ C CKS++ CFGSF E+ K++K + L AL +++NK + NF VN+ ++++IS A+MN+ N Y +I+++++A C+N K+ RKR+ ++E Q ++E N +S+ P+ LND ++ + ++K L+ Y L Q N QCWNG G + K +S + KT L+ IT +N++L +V DP+ ++ + KP + ++ +EGSG D EN Sbjct: 16 FIHLFFILLKFSYSTSSDECTKSTPMWYSLKYPYLNLLENYKLQNTA-FNCPILQTRNCCNSVILKEMSSVSEIKLKGFAEEKLENLLTMFSNDSYILMNMYLNDLENTKNDLNQLFSATYGYNYKVEKNFFFSWFDKLKMYMEGKKHNIGQLLDEFFLEMAGKIVKILIPPESSPEVTKCQIDRLIEAKPYQEADNSLKKNIIRSYAPSRMFVNAIAVGRDGFRALMNKITPSSNCVAQFNTQFHCMLCNGLTVKTCPVSCKSVMENCFGSFKLAELKKLDKIFTKYLSALFELANKLDNQLNFPAVNHKMNVQISTAIMNIQNIYPTIKEQIKAKCQNTGSKVRRKRQVAKEFVAWQTKLGDESPFWEKKLNDNLKSGVSKKTPVGSQNTKLNDFLSPMSRRIKTKYKALEGYFLRGVHDFCTLNSQSNESSSTQCWNGT--LPGIVTDKNNKKKLDKSSVS-VFKTVTNNLKDITMKINDLLRDKVPDPETVAVEDYLLYKSKPSSKRTGKPIKPTLAPSIEGSG----DFEN 543 The following BLAST results are available for this feature:
BLAST of glypican-1 vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of glypican-1 vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 1
BLAST of glypican-1 vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 4
BLAST of glypican-1 vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of glypican-1 vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of glypican-1 vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of glypican-1 vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of glypican-1 vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of glypican-1 vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of glypican-1 vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 0
BLAST of glypican-1 vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of glypican-1 vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 0
BLAST of glypican-1 vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of glypican-1 vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 3
Analyses
This transcript is derived from or has results from the following analyses Cross References
External references for this transcript
Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034893 ID=SMED30034893|Name=glypican-1|organism=Schmidtea mediterranea sexual|type=transcript|length=2530bpback to top protein sequence of SMED30034893-orf-1 >SMED30034893-orf-1 ID=SMED30034893-orf-1|Name=SMED30034893-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=752bp MNLSIDCLLIITVLFALFENQNAQNDVDCQAIKTRWYSHKYQYSDDLLKFback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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