Casein kinase II subunit alpha
|
Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Homology
BLAST of Casein kinase II subunit alpha vs. Ensembl Human
Match: CSNK2A1 (casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]) HSP 1 Score: 357.836 bits (917), Expect = 1.555e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. Ensembl Human
Match: CSNK2A1 (casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]) HSP 1 Score: 357.836 bits (917), Expect = 1.555e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. Ensembl Human
Match: CSNK2A1 (casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]) HSP 1 Score: 357.836 bits (917), Expect = 1.555e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. Ensembl Human
Match: CSNK2A1 (casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]) HSP 1 Score: 357.836 bits (917), Expect = 1.555e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. Ensembl Human
Match: CSNK2A1 (casein kinase 2 alpha 1 [Source:HGNC Symbol;Acc:HGNC:2457]) HSP 1 Score: 357.836 bits (917), Expect = 1.555e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. Ensembl Celegans
Match: kin-3 (Casein kinase II subunit alpha [Source:UniProtKB/Swiss-Prot;Acc:P18334]) HSP 1 Score: 356.295 bits (913), Expect = 7.346e-122 Identity = 179/318 (56.29%), Postives = 238/318 (74.84%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY++VN S+P+ Y +Y I + DDY +++K+GRGKYSEVF G + ST+ +V+K+LKPV + KIKRE+KIL NLRG NIITLL+VV DPIS+TP+ IFE++ N +FK+LY+ + DI YYL +LL ALD CHS GIMHRDVKP N++I+ + LRLIDWGLA+FYHPRQ YNVRVASRYFKGPELLV+++ YDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ +Y I L+ + ++ R+ K W +++ ENQHLV E+ LD LLR+DH RLTA+EA+ H +F
Sbjct: 6 SRARVYAEVNPSRPREYWDYEAHMIEWGQIDDYQLVRKLGRGKYSEVFEGFKMSTDEKVVVKILKPVKKKKIKREIKILENLRGGTNIITLLDVVKDPISRTPALIFEHVNNSDFKQLYQTLSDYDIRYYLYELLKALDFCHSQGIMHRDVKPHNVMIDAEKRELRLIDWGLAEFYHPRQDYNVRVASRYFKGPELLVDYQCYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIARYHIDLDPRFNDILGRHSRKRWERFIHAENQHLVTPEALDFLDKLLRYDHAERLTAQEAMGHEYF 323
BLAST of Casein kinase II subunit alpha vs. Ensembl Celegans
Match: cdk-12 (Cyclin-dependent kinase 12 [Source:UniProtKB/Swiss-Prot;Acc:P46551]) HSP 1 Score: 139.428 bits (350), Expect = 4.605e-36 Identity = 91/311 (29.26%), Postives = 172/311 (55.31%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLK--------PVAEMKIKRELKILSNLRGCENIITLLNVVMDPIS-----QTPS---FIFEYIENE-----NFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQK-YNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+++ +IG G Y +V+ V + T + +K ++ P+ + RE+KIL L +NI+ L+++V+D IS +T + +FEY++++ KEL +F K IC +QLL L H+ G +HRD+K NI++NN+ + L++ D GLA + + Y RV + +++ PELL+ E Y ++D+W+ GC+L G +F + +F G + QL I K G+ + +++ + ++ + +++ Y + + E +H++ +E+ LLD +L + + R++AKEAL+H + +
Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAI---REIKILRQLH-HKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELV-DFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGE-LKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCML-GELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTEL-VGWNTFRMKRTY-----QRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWIRSL 608
BLAST of Casein kinase II subunit alpha vs. Ensembl Celegans
Match: cdk-12 (Cyclin-dependent kinase 12 [Source:UniProtKB/Swiss-Prot;Acc:P46551]) HSP 1 Score: 139.428 bits (350), Expect = 5.133e-36 Identity = 91/311 (29.26%), Postives = 172/311 (55.31%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLK--------PVAEMKIKRELKILSNLRGCENIITLLNVVMDPIS-----QTPS---FIFEYIENE-----NFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQK-YNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+++ +IG G Y +V+ V + T + +K ++ P+ + RE+KIL L +NI+ L+++V+D IS +T + +FEY++++ KEL +F K IC +QLL L H+ G +HRD+K NI++NN+ + L++ D GLA + + Y RV + +++ PELL+ E Y ++D+W+ GC+L G +F + +F G + QL I K G+ + +++ + ++ + +++ Y + + E +H++ +E+ LLD +L + + R++AKEAL+H + +
Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAI---REIKILRQLH-HKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELV-DFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGE-LKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCML-GELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTEL-VGWNTFRMKRTY-----QRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWIRSL 608
BLAST of Casein kinase II subunit alpha vs. Ensembl Celegans
Match: cdk-12 (Cyclin-dependent kinase 12 [Source:UniProtKB/Swiss-Prot;Acc:P46551]) HSP 1 Score: 139.428 bits (350), Expect = 5.278e-36 Identity = 91/311 (29.26%), Postives = 172/311 (55.31%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLK--------PVAEMKIKRELKILSNLRGCENIITLLNVVMDPIS-----QTPS---FIFEYIENE-----NFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQK-YNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+++ +IG G Y +V+ V + T + +K ++ P+ + RE+KIL L +NI+ L+++V+D IS +T + +FEY++++ KEL +F K IC +QLL L H+ G +HRD+K NI++NN+ + L++ D GLA + + Y RV + +++ PELL+ E Y ++D+W+ GC+L G +F + +F G + QL I K G+ + +++ + ++ + +++ Y + + E +H++ +E+ LLD +L + + R++AKEAL+H + +
Sbjct: 311 YTMLDQIGEGTYGQVYKAVNNLTGEQVALKRVRLENEKEGFPITAI---REIKILRQLH-HKNIVRLMDIVIDDISMDELKRTRANFYLVFEYVDHDLIGLLESKELV-DFNKDQICSLFKQLLEGLAYIHNTGFLHRDIKCSNILVNNKGE-LKIADLGLARLWEKESRLYTNRVITLWYRPPELLLGDERYGPAIDVWSTGCML-GELFTRKPLFNGNNEFGQLELISKVCGSPNVDNWPELTEL-VGWNTFRMKRTY-----QRRIREEFEHIMPREAVDLLDKMLTLNPEKRISAKEALNHPWIRSL 608
BLAST of Casein kinase II subunit alpha vs. Ensembl Celegans
Match: cdk-1 (Cyclin-dependent kinase 1 [Source:UniProtKB/Swiss-Prot;Acc:P34556]) HSP 1 Score: 125.946 bits (315), Expect = 5.863e-33 Identity = 92/308 (29.87%), Postives = 157/308 (50.97%), Query Frame = 3
Query: 150 SCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAE-----MKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMD------ICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYH-PRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGT-TSFE----SYLKKYQIKL-NLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
+ +D++ ++KIG G Y V+ G TN + +K ++ +E RE+ +L L+ N++ L V+M IFE++ + + K K + + Y Q+L A+ CH ++HRD+KPQN++++N ++L D+GLA P + Y V + +++ PE+L+ + Y +D+W++GC+ A M KK +FQG +D+L +I + LGT T E L Y+ +E LR ++ Y +HL+ +F LL+ LL +D RL AK+AL H +F
Sbjct: 18 TLNDFTKLEKIGEGTYGVVYKGKNRRTNAMVAMKKIRLESEDEGVPSTAVREISLLKELQ-HPNVVGLEAVIMQ--ENRLFLIFEFL-SFDLKRYMDQLGKDEYLPLETLKSYTFQILQAMCFCHQRRVIHRDLKPQNLLVDN-NGAIKLADFGLARAIGIPIRVYTHEVVTLWYRAPEILMGAQRYSMGVDMWSIGCIFAEMATKK-PLFQGDSEIDELFRIFRVLGTPTELEWNGVESLPDYKATFPKWRENFLRDKF-------YDKKTGKHLLDDTAFSLLEGLLIYDPSLRLNAKKALVHPYF 312
BLAST of Casein kinase II subunit alpha vs. Ensembl Fly
Match: CkIIalpha (gene:FBgn0264492 transcript:FBtr0344974) HSP 1 Score: 356.681 bits (914), Expect = 3.271e-122 Identity = 179/318 (56.29%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN KP Y +Y + + + + DDY +++K+GRGKYSEVF + +T V+K+LKPV + KIKRE+KIL NLRG NIITLL VV DP+S+TP+ IFE++ N +FK+LY+ T +I YYL +LL ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT +YL KY I L+ + ++ +R+ K W ++V ++NQHLV E+ LD LLR+DH RLTA+EA++H +F
Sbjct: 5 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
BLAST of Casein kinase II subunit alpha vs. Ensembl Fly
Match: CkIIalpha (gene:FBgn0264492 transcript:FBtr0070044) HSP 1 Score: 356.681 bits (914), Expect = 3.271e-122 Identity = 179/318 (56.29%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN KP Y +Y + + + + DDY +++K+GRGKYSEVF + +T V+K+LKPV + KIKRE+KIL NLRG NIITLL VV DP+S+TP+ IFE++ N +FK+LY+ T +I YYL +LL ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT +YL KY I L+ + ++ +R+ K W ++V ++NQHLV E+ LD LLR+DH RLTA+EA++H +F
Sbjct: 5 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
BLAST of Casein kinase II subunit alpha vs. Ensembl Fly
Match: CkIIalpha (gene:FBgn0264492 transcript:FBtr0345138) HSP 1 Score: 356.681 bits (914), Expect = 3.271e-122 Identity = 179/318 (56.29%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN KP Y +Y + + + + DDY +++K+GRGKYSEVF + +T V+K+LKPV + KIKRE+KIL NLRG NIITLL VV DP+S+TP+ IFE++ N +FK+LY+ T +I YYL +LL ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT +YL KY I L+ + ++ +R+ K W ++V ++NQHLV E+ LD LLR+DH RLTA+EA++H +F
Sbjct: 5 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
BLAST of Casein kinase II subunit alpha vs. Ensembl Fly
Match: CkIIalpha (gene:FBgn0264492 transcript:FBtr0111141) HSP 1 Score: 356.681 bits (914), Expect = 3.271e-122 Identity = 179/318 (56.29%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN KP Y +Y + + + + DDY +++K+GRGKYSEVF + +T V+K+LKPV + KIKRE+KIL NLRG NIITLL VV DP+S+TP+ IFE++ N +FK+LY+ T +I YYL +LL ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT +YL KY I L+ + ++ +R+ K W ++V ++NQHLV E+ LD LLR+DH RLTA+EA++H +F
Sbjct: 5 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
BLAST of Casein kinase II subunit alpha vs. Ensembl Fly
Match: CkIIalpha (gene:FBgn0264492 transcript:FBtr0070043) HSP 1 Score: 356.681 bits (914), Expect = 3.271e-122 Identity = 179/318 (56.29%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN KP Y +Y + + + + DDY +++K+GRGKYSEVF + +T V+K+LKPV + KIKRE+KIL NLRG NIITLL VV DP+S+TP+ IFE++ N +FK+LY+ T +I YYL +LL ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT +YL KY I L+ + ++ +R+ K W ++V ++NQHLV E+ LD LLR+DH RLTA+EA++H +F
Sbjct: 5 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
BLAST of Casein kinase II subunit alpha vs. Ensembl Zebrafish
Match: csnk2a4 (casein kinase 2, alpha 4 polypeptide [Source:ZFIN;Acc:ZDB-GENE-141210-9]) HSP 1 Score: 372.474 bits (955), Expect = 1.486e-127 Identity = 167/319 (52.35%), Postives = 238/319 (74.61%), Query Frame = 3
Query: 63 ESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
+S +RVY++VN +PK Y +Y + + +D+ ++ K+G GKYS+VF + + N +V+K LKPV KI RE+KIL NLRG NII+L+++V DP+ +TP+ +FE++ N +FK+LY++ T DI +Y+ ++L ALD HSMGIMHRDVKP NI+I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELL++++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT Y+ KY I+L+ + + R+ K W ++V NENQHL+ E+ LD LLR+DHQTRLTA+EA+ H++F
Sbjct: 6 KSRARVYTEVNTHRPKEYWDYQSHKPQWGNHEDFQMVTKLGIGKYSDVFEAINITNNEKVVVKTLKPVKRKKILREVKILENLRGGPNIISLIDMVKDPVIRTPALVFEHVNNTDFKQLYQSLTDYDIRFYMFEILKALDFSHSMGIMHRDVKPHNIMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLIDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGRDNYDQLVRIAKVLGTDGLYDYIDKYNIELDPRFIEILGRHSRKRWKKFVHNENQHLISPEALDFLDKLLRYDHQTRLTAQEAMEHQYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Zebrafish
Match: csnk2a1 (casein kinase 2, alpha 1 polypeptide [Source:ZFIN;Acc:ZDB-GENE-990415-27]) HSP 1 Score: 357.066 bits (915), Expect = 9.206e-122 Identity = 174/319 (54.55%), Postives = 242/319 (75.86%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFA 1022
S SRVY DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL+++ DP+S+TP+ +FE++ N +FK+LY+ + DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F+
Sbjct: 7 SRSRVYPDVNTQRPREYWDYESHVVDWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDIIKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPNQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMDHSYFS 325
BLAST of Casein kinase II subunit alpha vs. Ensembl Zebrafish
Match: zgc:86598 (zgc:86598 [Source:ZFIN;Acc:ZDB-GENE-040625-181]) HSP 1 Score: 357.451 bits (916), Expect = 1.204e-121 Identity = 174/318 (54.72%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S SRVY DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL+++ DP+S+TP+ +FE++ N +FK+LY+ + DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRSRVYPDVNTQRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDIIKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMEHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Zebrafish
Match: zgc:86598 (zgc:86598 [Source:ZFIN;Acc:ZDB-GENE-040625-181]) HSP 1 Score: 357.451 bits (916), Expect = 1.204e-121 Identity = 174/318 (54.72%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S SRVY DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL+++ DP+S+TP+ +FE++ N +FK+LY+ + DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRSRVYPDVNTQRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDIIKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMEHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Zebrafish
Match: zgc:86598 (zgc:86598 [Source:ZFIN;Acc:ZDB-GENE-040625-181]) HSP 1 Score: 357.451 bits (916), Expect = 1.204e-121 Identity = 174/318 (54.72%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S SRVY DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL+++ DP+S+TP+ +FE++ N +FK+LY+ + DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRSRVYPDVNTQRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDIIKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMEHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Xenopus
Match: csnk2a2 (casein kinase 2 alpha 2 [Source:NCBI gene;Acc:493442]) HSP 1 Score: 347.436 bits (890), Expect = 1.845e-118 Identity = 175/318 (55.03%), Postives = 240/318 (75.47%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN + + Y +Y + + +DY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII LL+ + DP+S+TP+ +FEYI N +FK+LY+ T DI YY+ +LL ALD CHS G+MHRDVKP N++I+++ K LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT SYLKKY I+L+ ++ ++ K W ++ +EN+HLV E+ LLD LLR+DHQ RLTA+EA+ H +F
Sbjct: 8 SKARVYADVNSLRSREYWDYEAHVPNWGNQEDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIRLLDTIKDPVSKTPALVFEYINNTDFKQLYQILTDYDIRYYMYELLKALDYCHSQGVMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYSYLKKYHIELDPHFNDILGQHSRKRWENFLHSENRHLVSAEALDLLDKLLRYDHQQRLTAREAMDHPYF 325
BLAST of Casein kinase II subunit alpha vs. Ensembl Xenopus
Match: csnk2a2 (casein kinase 2 alpha 2 [Source:NCBI gene;Acc:493442]) HSP 1 Score: 348.206 bits (892), Expect = 2.128e-118 Identity = 175/318 (55.03%), Postives = 240/318 (75.47%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN + + Y +Y + + +DY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII LL+ + DP+S+TP+ +FEYI N +FK+LY+ T DI YY+ +LL ALD CHS G+MHRDVKP N++I+++ K LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT SYLKKY I+L+ ++ ++ K W ++ +EN+HLV E+ LLD LLR+DHQ RLTA+EA+ H +F
Sbjct: 8 SKARVYADVNSLRSREYWDYEAHVPNWGNQEDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIRLLDTIKDPVSKTPALVFEYINNTDFKQLYQILTDYDIRYYMYELLKALDYCHSQGVMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYSYLKKYHIELDPHFNDILGQHSRKRWENFLHSENRHLVSAEALDLLDKLLRYDHQQRLTAREAMDHPYF 325
BLAST of Casein kinase II subunit alpha vs. Ensembl Xenopus
Match: fndc4 (fibronectin type III domain containing 4 [Source:Xenbase;Acc:XB-GENE-997773]) HSP 1 Score: 338.961 bits (868), Expect = 1.467e-114 Identity = 166/291 (57.04%), Postives = 226/291 (77.66%), Query Frame = 3
Query: 147 QSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
Q+ DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQTRLTA+EA+ H +F
Sbjct: 6 QNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQTRLTAREAMDHPYF 296
BLAST of Casein kinase II subunit alpha vs. Ensembl Xenopus
Match: fndc4 (fibronectin type III domain containing 4 [Source:Xenbase;Acc:XB-GENE-997773]) HSP 1 Score: 337.806 bits (865), Expect = 2.578e-114 Identity = 165/288 (57.29%), Postives = 224/288 (77.78%), Query Frame = 3
Query: 156 DDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQTRLTA+EA+ H +F
Sbjct: 2 DDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQTRLTAREAMDHPYF 289
BLAST of Casein kinase II subunit alpha vs. Ensembl Xenopus
Match: fndc4 (fibronectin type III domain containing 4 [Source:Xenbase;Acc:XB-GENE-997773]) HSP 1 Score: 333.954 bits (855), Expect = 1.317e-113 Identity = 165/288 (57.29%), Postives = 224/288 (77.78%), Query Frame = 3
Query: 156 DDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQTRLTA+EA+ H +F
Sbjct: 2 DDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQTRLTAREAMDHPYF 289
BLAST of Casein kinase II subunit alpha vs. Ensembl Mouse
Match: Csnk2a1 (casein kinase 2, alpha 1 polypeptide [Source:MGI Symbol;Acc:MGI:88543]) HSP 1 Score: 358.221 bits (918), Expect = 5.929e-122 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. Ensembl Mouse
Match: Csnk2a2 (casein kinase 2, alpha prime polypeptide [Source:MGI Symbol;Acc:MGI:88547]) HSP 1 Score: 347.051 bits (889), Expect = 4.252e-118 Identity = 176/324 (54.32%), Postives = 241/324 (74.38%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY++VN + + Y +Y ++ + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FEYI N +FK+LY+ T DI +Y+ +LL ALD CHS GIMHRDVKP N++I+++ K LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT YLKKY I L+ ++ ++ K W ++ +EN+HLV E+ LLD LLR+DHQ RLTAKEA+ H +F +E
Sbjct: 8 SRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKE 331
BLAST of Casein kinase II subunit alpha vs. Ensembl Mouse
Match: Csnk2a2 (casein kinase 2, alpha prime polypeptide [Source:MGI Symbol;Acc:MGI:88547]) HSP 1 Score: 347.051 bits (889), Expect = 4.252e-118 Identity = 176/324 (54.32%), Postives = 241/324 (74.38%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY++VN + + Y +Y ++ + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FEYI N +FK+LY+ T DI +Y+ +LL ALD CHS GIMHRDVKP N++I+++ K LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT YLKKY I L+ ++ ++ K W ++ +EN+HLV E+ LLD LLR+DHQ RLTAKEA+ H +F +E
Sbjct: 8 SRARVYAEVNSLRSREYWDYEAHVPSWGNQDDYQLVRKLGRGKYSEVFEAINITNNERVVVKILKPVKKKKIKREVKILENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKE 331
BLAST of Casein kinase II subunit alpha vs. Ensembl Mouse
Match: Csnk2a2 (casein kinase 2, alpha prime polypeptide [Source:MGI Symbol;Acc:MGI:88547]) HSP 1 Score: 261.536 bits (667), Expect = 3.119e-86 Identity = 120/210 (57.14%), Postives = 158/210 (75.24%), Query Frame = 3
Query: 408 FKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
K+LY+ T DI +Y+ +LL ALD CHS GIMHRDVKP N++I+++ K LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT YLKKY I L+ ++ ++ K W ++ +EN+HLV E+ LLD LLR+DHQ RLTAKEA+ H +F +E
Sbjct: 7 LKQLYQILTDFDIRFYMYELLKALDYCHSKGIMHRDVKPHNVMIDHQQKKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKE 216
BLAST of Casein kinase II subunit alpha vs. Ensembl Mouse
Match: Csnk2a2 (casein kinase 2, alpha prime polypeptide [Source:MGI Symbol;Acc:MGI:88547]) HSP 1 Score: 253.447 bits (646), Expect = 6.683e-83 Identity = 123/246 (50.00%), Postives = 163/246 (66.26%), Query Frame = 3
Query: 300 LSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
L NLRG NII L++ V DP+S+TP+ +FEYI N +FK+LY+ T DI +Y+ +LL LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT YLKKY I L+ ++ ++ K W ++ +EN+HLV E+ LLD LLR+DHQ RLTAKEA+ H +F +E
Sbjct: 19 LENLRGGTNIIKLIDTVKDPVSKTPALVFEYINNTDFKQLYQILTDFDIRFYMYELL----------------------------KLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGQDNYDQLVRIAKVLGTDELYGYLKKYHIDLDPHFNDILGQHSRKRWENFIHSENRHLVSPEALDLLDKLLRYDHQQRLTAKEAMEHPYFYPVVKE 236
BLAST of Casein kinase II subunit alpha vs. UniProt/SwissProt
Match: sp|P40231|CSK2A_SCHPO (Casein kinase II subunit alpha OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=cka1 PE=2 SV=2) HSP 1 Score: 363.614 bits (932), Expect = 5.298e-124 Identity = 173/318 (54.40%), Postives = 233/318 (73.27%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S+SRVY+ VN+ P+ Y +Y ++ + D+Y II+K+GRGKYSEVF G+ N +IKVLKPV KIKRE+KIL NL G NII+LL++V DP S+TPS IFE+++N +F+ LY + DI YY +LL ALD CHS GIMHRDVKP N++I+++ + LRLIDWGLA+FYH +YNVRVASRYFKGPELLV+F YDYSLD+W+ G + A +IFKKDT F+G+DN DQL+KI K LGT +Y++KYQI L+ + N+ +YP + W +V+ +N+ L E+ LL+ LLR+DHQ RLT +EA++H +F
Sbjct: 11 SVSRVYAHVNEEMPREYWDYENMQEVFGYQDNYEIIRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIKREIKILQNLAGGPNIISLLDIVRDPESKTPSLIFEFVDNIDFRTLYPTLSDYDIRYYSYELLKALDFCHSRGIMHRDVKPHNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVRVASRYFKGPELLVDFREYDYSLDIWSFGVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTDELFAYVQKYQIVLDRQYDNILGQYPKRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQERLTCQEAMAHPYF 328
BLAST of Casein kinase II subunit alpha vs. UniProt/SwissProt
Match: sp|P08181|CSK2A_DROME (Casein kinase II subunit alpha OS=Drosophila melanogaster OX=7227 GN=CkIIalpha PE=1 SV=2) HSP 1 Score: 356.681 bits (914), Expect = 3.279e-121 Identity = 179/318 (56.29%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN KP Y +Y + + + + DDY +++K+GRGKYSEVF + +T V+K+LKPV + KIKRE+KIL NLRG NIITLL VV DP+S+TP+ IFE++ N +FK+LY+ T +I YYL +LL ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT +YL KY I L+ + ++ +R+ K W ++V ++NQHLV E+ LD LLR+DH RLTA+EA++H +F
Sbjct: 5 SAARVYTDVNAHKPDEYWDYENYVVDWGNQDDYQLVRKLGRGKYSEVFEAINITTTEKCVVKILKPVKKKKIKREIKILENLRGGTNIITLLAVVKDPVSRTPALIFEHVNNTDFKQLYQTLTDYEIRYYLFELLKALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEELYAYLDKYNIDLDPRFHDILQRHSRKRWERFVHSDNQHLVSPEALDFLDKLLRYDHVDRLTAREAMAHPYF 322
BLAST of Casein kinase II subunit alpha vs. UniProt/SwissProt
Match: sp|P19139|CSK21_RAT (Casein kinase II subunit alpha OS=Rattus norvegicus OX=10116 GN=Csnk2a1 PE=1 SV=2) HSP 1 Score: 358.221 bits (918), Expect = 4.147e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. UniProt/SwissProt
Match: sp|Q60737|CSK21_MOUSE (Casein kinase II subunit alpha OS=Mus musculus OX=10090 GN=Csnk2a1 PE=1 SV=2) HSP 1 Score: 358.221 bits (918), Expect = 4.147e-121 Identity = 175/320 (54.69%), Postives = 243/320 (75.94%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ+RLTA+EA+ H +F T
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYT 326
BLAST of Casein kinase II subunit alpha vs. UniProt/SwissProt
Match: sp|P28020|CSK21_XENLA (Casein kinase II subunit alpha OS=Xenopus laevis OX=8355 GN=csnk2a1 PE=2 SV=2) HSP 1 Score: 358.221 bits (918), Expect = 4.779e-121 Identity = 175/318 (55.03%), Postives = 242/318 (76.10%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITL ++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQTRLTA+EA+ H +F
Sbjct: 7 SRARVYTDVNTHRPRDYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQTRLTAREAMDHPYF 324
BLAST of Casein kinase II subunit alpha vs. TrEMBL
Match: A0A1S8X841 (Kinase domain protein (Fragment) OS=Opisthorchis viverrini OX=6198 GN=X801_01255 PE=3 SV=1) HSP 1 Score: 394.43 bits (1012), Expect = 3.298e-133 Identity = 185/321 (57.63%), Postives = 238/321 (74.14%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
S +RVY+DV ++P+ Y +Y I + +DY I+KK+GRGKYSEVF G+ +TN VIK LKPV + KI RE+KIL NLRG NII L VV D S+TP+ IFE+++N +FKELY+ + DI YYL +LL ALD CHSMGIMHRDVKP NI+IN+ + LRLIDWGLA+FYHP Q+YNVRVASR++KGPELLV+++MYDYSLDLW+VGCV A MI +++ F G DN +QL++I + LGT YL KY IKL+ + + L R+P K W ++V ENQHLVC E+ LLD LLR+DHQ RLTA+EA+ H +F+ F
Sbjct: 5 SKARVYADVTANRPREYWDYEAHQIRWGDQEDYQIVKKLGRGKYSEVFEGINVTTNEKCVIKALKPVKKAKIAREIKILENLRGLTNIIILEAVVRDVKSRTPALIFEHVDNTDFKELYQTLSDHDIRYYLFELLRALDVCHSMGIMHRDVKPHNILINHTERQLRLIDWGLAEFYHPGQEYNVRVASRHYKGPELLVDYQMYDYSLDLWSVGCVFASMILRREPFFHGHDNYNQLVRITRVLGTDELFQYLNKYDIKLDARFSELIDRHPRKRWDRFVHPENQHLVCPEALDLLDKLLRYDHQERLTAREAMEHPYFSKF 325
BLAST of Casein kinase II subunit alpha vs. TrEMBL
Match: H2KQF0 (Casein kinase II subunit alpha OS=Clonorchis sinensis OX=79923 GN=CLF_103780 PE=3 SV=1) HSP 1 Score: 393.275 bits (1009), Expect = 6.563e-133 Identity = 185/324 (57.10%), Postives = 238/324 (73.46%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+DV ++P+ Y +Y I + +DY I+KK+GRGKYSEVF G+ +TN VIK LKPV + KI RE+KIL NLRG NII L VV D S+TP+ IFE+++N +FKELY+ + DI YYL +LL ALD CHSMGIMHRDVKP NI+IN+ + LRLIDWGLA+FYHP Q+YNVRVASR++KGPELLV+++MYDYSLDLW+VGCV A MI +++ F G DN +QL++I + LGT YL KY IKL+ + + L R+P K W ++V ENQHLVC E+ LLD LLR+DHQ RLTA+EA+ H +F + E
Sbjct: 5 SKARVYADVTANRPREYWDYEAHQIRWGDQEDYQIVKKLGRGKYSEVFEGINVTTNEKCVIKALKPVKKAKIAREIKILENLRGLTNIIILEAVVRDVKSRTPALIFEHVDNTDFKELYQTLSDHDIRYYLFELLRALDVCHSMGIMHRDVKPHNILINHSERQLRLIDWGLAEFYHPGQEYNVRVASRHYKGPELLVDYQMYDYSLDLWSVGCVFASMILRREPFFHGHDNYNQLVRITRVLGTDELFQYLNKYDIKLDARFSELIDRHPRKRWDRFVHPENQHLVCPEALDLLDKLLRYDHQERLTAREAMEHPYFKSIVLE 328
BLAST of Casein kinase II subunit alpha vs. TrEMBL
Match: A0A074ZJP6 (Protein kinase domain-containing protein OS=Opisthorchis viverrini OX=6198 GN=T265_06643 PE=3 SV=1) HSP 1 Score: 392.119 bits (1006), Expect = 1.642e-132 Identity = 185/324 (57.10%), Postives = 238/324 (73.46%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+DV ++P+ Y +Y I + +DY I+KK+GRGKYSEVF G+ +TN VIK LKPV + KI RE+KIL NLRG NII L VV D S+TP+ IFE+++N +FKELY+ + DI YYL +LL ALD CHSMGIMHRDVKP NI+IN+ + LRLIDWGLA+FYHP Q+YNVRVASR++KGPELLV+++MYDYSLDLW+VGCV A MI +++ F G DN +QL++I + LGT YL KY IKL+ + + L R+P K W ++V ENQHLVC E+ LLD LLR+DHQ RLTA+EA+ H +F + E
Sbjct: 5 SKARVYADVTANRPREYWDYEAHQIRWGDQEDYQIVKKLGRGKYSEVFEGINVTTNEKCVIKALKPVKKAKIAREIKILENLRGLTNIIILEAVVRDVKSRTPALIFEHVDNTDFKELYQTLSDHDIRYYLFELLRALDVCHSMGIMHRDVKPHNILINHTERQLRLIDWGLAEFYHPGQEYNVRVASRHYKGPELLVDYQMYDYSLDLWSVGCVFASMILRREPFFHGHDNYNQLVRITRVLGTDELFQYLNKYDIKLDARFSELIDRHPRKRWDRFVHPENQHLVCPEALDLLDKLLRYDHQERLTAREAMEHPYFKSIVLE 328
BLAST of Casein kinase II subunit alpha vs. TrEMBL
Match: A0A4S2LLK0 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006336 PE=3 SV=1) HSP 1 Score: 392.119 bits (1006), Expect = 1.734e-132 Identity = 185/324 (57.10%), Postives = 238/324 (73.46%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+DV ++P+ Y +Y I + +DY I+KK+GRGKYSEVF G+ +TN VIK LKPV + KI RE+KIL NLRG NII L VV D S+TP+ IFE+++N +FKELY+ + DI YYL +LL ALD CHSMGIMHRDVKP NI+IN+ + LRLIDWGLA+FYHP Q+YNVRVASR++KGPELLV+++MYDYSLDLW+VGCV A MI +++ F G DN +QL++I + LGT YL KY IKL+ + + L R+P K W ++V ENQHLVC E+ LLD LLR+DHQ RLTA+EA+ H +F + E
Sbjct: 5 SKARVYADVTANRPREYWDYEAHQIRWGDQEDYQIVKKLGRGKYSEVFEGINVTTNEKCVIKALKPVKKAKIAREIKILENLRGLTNIIILEAVVRDVKSRTPALIFEHVDNTDFKELYQTLSDHDIRYYLFELLRALDVCHSMGIMHRDVKPHNILINHTERQLRLIDWGLAEFYHPGQEYNVRVASRHYKGPELLVDYQMYDYSLDLWSVGCVFASMILRREPFFHGHDNYNQLVRITRVLGTDELFQYLNKYDIKLDARFSELIDRHPRKRWDRFVHPENQHLVCPEALDLLDKLLRYDHQERLTAREAMEHPYFKSIVLE 328
BLAST of Casein kinase II subunit alpha vs. TrEMBL
Match: A0A4S2LLJ9 (Protein kinase domain-containing protein OS=Opisthorchis felineus OX=147828 GN=CRM22_006336 PE=3 SV=1) HSP 1 Score: 392.119 bits (1006), Expect = 3.139e-132 Identity = 185/324 (57.10%), Postives = 238/324 (73.46%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+DV ++P+ Y +Y I + +DY I+KK+GRGKYSEVF G+ +TN VIK LKPV + KI RE+KIL NLRG NII L VV D S+TP+ IFE+++N +FKELY+ + DI YYL +LL ALD CHSMGIMHRDVKP NI+IN+ + LRLIDWGLA+FYHP Q+YNVRVASR++KGPELLV+++MYDYSLDLW+VGCV A MI +++ F G DN +QL++I + LGT YL KY IKL+ + + L R+P K W ++V ENQHLVC E+ LLD LLR+DHQ RLTA+EA+ H +F + E
Sbjct: 5 SKARVYADVTANRPREYWDYEAHQIRWGDQEDYQIVKKLGRGKYSEVFEGINVTTNEKCVIKALKPVKKAKIAREIKILENLRGLTNIIILEAVVRDVKSRTPALIFEHVDNTDFKELYQTLSDHDIRYYLFELLRALDVCHSMGIMHRDVKPHNILINHTERQLRLIDWGLAEFYHPGQEYNVRVASRHYKGPELLVDYQMYDYSLDLWSVGCVFASMILRREPFFHGHDNYNQLVRITRVLGTDELFQYLNKYDIKLDARFSELIDRHPRKRWDRFVHPENQHLVCPEALDLLDKLLRYDHQERLTAREAMEHPYFKSIVLE 328
BLAST of Casein kinase II subunit alpha vs. Ensembl Cavefish
Match: csnk2a1 (casein kinase II subunit alpha-like [Source:NCBI gene;Acc:103028340]) HSP 1 Score: 357.836 bits (917), Expect = 9.454e-122 Identity = 175/318 (55.03%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S SRVY DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL++V DP+S+TP+ +FE++ N +FK+LY+ + DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRSRVYPDVNTQRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDIVKDPVSRTPALVFEHVNNTDFKQLYQTLSDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPNQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMDHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Cavefish
Match: csnk2a4 (casein kinase II subunit alpha [Source:NCBI gene;Acc:103042686]) HSP 1 Score: 352.443 bits (903), Expect = 9.240e-120 Identity = 171/318 (53.77%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY++VN +P+ Y +Y + + + DD+ +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII+L+++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRARVYTEVNTHRPREYWDYESHVVEWGNQDDFQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIISLIDIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELEPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQARLTAREAMEHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Cavefish
Match: csnk2a4 (casein kinase II subunit alpha [Source:NCBI gene;Acc:103042686]) HSP 1 Score: 351.288 bits (900), Expect = 1.254e-119 Identity = 171/318 (53.77%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY++VN +P+ Y +Y + + + DD+ +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII+L+++V DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRARVYTEVNTHRPREYWDYESHVVEWGNQDDFQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIISLIDIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELEPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQARLTAREAMEHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Cavefish
Match: csnk2a2b (casein kinase 2 alpha 2 [Source:NCBI gene;Acc:103042119]) HSP 1 Score: 349.747 bits (896), Expect = 3.245e-119 Identity = 178/318 (55.97%), Postives = 239/318 (75.16%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN K + Y +Y ++ + +DY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FE I N +FKELY+ T DI +Y+ +LL ALD CHSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT YL+KY I+L+ + +L + K W Q+V ENQHLV E+ LLD LLR+DHQ RLTA EA+ H +F
Sbjct: 8 SKARVYADVNTLKSREYWDYEAHVPSWSNQEDYQLVRKLGRGKYSEVFEAININNNEKVVVKILKPVKKKKIKREIKILENLRGGTNIIRLVDTVKDPVSRTPALVFECINNTDFKELYQKLTDFDIRFYMYELLKALDYCHSMGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFQKEPFFHGQDNYDQLVRIAKVLGTDELFGYLRKYHIELDPRFKDLLGQQTRKRWEQFVQTENQHLVSPEALDLLDKLLRYDHQQRLTATEAMEHPYF 325
BLAST of Casein kinase II subunit alpha vs. Ensembl Cavefish
Match: csnk2a2a (casein kinase 2, alpha prime polypeptide a [Source:ZFIN;Acc:ZDB-GENE-990415-28]) HSP 1 Score: 343.199 bits (879), Expect = 1.930e-115 Identity = 177/320 (55.31%), Postives = 238/320 (74.38%), Query Frame = 3
Query: 60 TESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN K K Y +Y ++ + DDY +++K+GRGKYSEVF + ++N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FE I N +FK+LY+ T DI +YL +LL ALD HSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP Q+YNVRVASR +KGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT SYL KY I+L+ + +L + K W +V ENQHLV E+ LLD LLR+DHQ RLTA+EA+ H +F
Sbjct: 96 AASKARVYADVNTLKSKDYWDYEAHVPSWSNQDDYQLVRKLGRGKYSEVFEAININSNDRVVVKILKPVKKKKIKREIKILENLRGGTNIIRLVDTVKDPVSRTPALVFECINNTDFKDLYQRLTDFDIRFYLYELLKALDYSHSMGIMHRDVKPHNVMIDHQMRKLRLIDWGLAEFYHPSQEYNVRVASRSYKGPELLVDYQMYDYSLDMWSLGCMLASMIFQKEPFFHGQDNYDQLVRIAKVLGTEELYSYLNKYHIELDTRFKDLLGQQTRKRWEHFVQPENQHLVSPEALDLLDKLLRYDHQQRLTAQEAMEHPYF 415
BLAST of Casein kinase II subunit alpha vs. Ensembl Sea Lamprey
Match: CSNK2A2 (casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459]) HSP 1 Score: 362.459 bits (929), Expect = 2.516e-124 Identity = 179/324 (55.25%), Postives = 245/324 (75.62%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL+VV DP+S+TP+ +FE++ N +FK+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLDLW++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQTRLTA+EA+ H +F +E
Sbjct: 7 SRARVYTDVNTHRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLLDVVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILRALDYCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDLWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQTRLTAREAMEHPYFYPIVKE 330
BLAST of Casein kinase II subunit alpha vs. Ensembl Sea Lamprey
Match: CSNK2A2 (casein kinase 2 alpha 2 [Source:HGNC Symbol;Acc:HGNC:2459]) HSP 1 Score: 348.206 bits (892), Expect = 9.528e-119 Identity = 170/324 (52.47%), Postives = 241/324 (74.38%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S ++Y++ N + + Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NIITLL++V DP+S+TP+ +FEY+ N ++K+LY+ T DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I + LGT +Y+ KY I L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQTRLT +EA+ H +F +E
Sbjct: 7 SRPKLYAEANSHRARDYWDYEAHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILQNLRGGPNIITLLDIVKDPVSRTPALVFEYVNNTDYKQLYQTLTDQDIRFYMYEILKALDFCHSMGIMHRDVKPHNVMIDHENRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIARVLGTEELYTYIDKYNIDLDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQTRLTPREAMEHPYFYPVVKE 330
BLAST of Casein kinase II subunit alpha vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 127.872 bits (320), Expect = 1.525e-34 Identity = 91/307 (29.64%), Postives = 156/307 (50.81%), Query Frame = 3
Query: 156 DDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMK-----IKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICY-----YLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLA-DFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFH---LLDNLLRFDHQTRLTAKEALSHRFFATFSQ 1034
D++ ++KIG G Y V+ T + +K ++ E + RE+ +L L NI+ LL ++ + +FE ++ ++ K+ N T I YL QLL + CHS I+HRD+KPQN++IN ++L D+GLA F P++ Y V + +++ PE+L+ + Y S+D+W++GC+ A M+ ++ +F G +DQL +I +TLGT + Q+ + + +P ++ + E +V +F LL +L++D R+TA ALSH FF Q
Sbjct: 2 DNFQKVEKIGEGTYGVVYKARNKLTGEAVALKKIRLDTETEGVPSTAIREISLLRELNH-PNIVRLLTIIHS--EKKLYLVFELLD-QDLKKFMDNATPSGIPLPLVKSYLYQLLQGIAFCHSHRILHRDLKPQNLLINAE-GAIKLADFGLARAFGVPQRTYTHEVVTLWYRAPEILLGCKHYSTSVDVWSIGCIFAEMLTRR-ALFPGDSEIDQLFRIFRTLGTPDEVVWPGVSQL------PDYKSTFP-----RWANQELTKVVPTLNFEGRDLLALMLQYDPNQRVTANMALSHCFFQNVKQ 291
BLAST of Casein kinase II subunit alpha vs. Ensembl Sea Lamprey
Match: mapk1 (mitogen-activated protein kinase 1 [Source:ZFIN;Acc:ZDB-GENE-030722-2]) HSP 1 Score: 127.872 bits (320), Expect = 6.332e-34 Identity = 91/304 (29.93%), Postives = 156/304 (51.32%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEM----KIKRELKILSNLRGCENIITLLNVV-MDPISQTPS--FIFEYIENENFKELY-KNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNV----RVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIK---PWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+ + IG G Y V ++ + IK + P + RE+KIL + ENII + +++ I Q + + +E + +K L + + ICY+L Q+L L HS ++HRD+KP N+++N T L++ D+GLA P + VA+R+++ PE+++N + Y S+D+W+VGC+LA M+ + +F GK +DQL I+ LG+ S E +N+K N + P K PW++ + ++ LLD +L F+ R+T +EAL+H + +
Sbjct: 36 YTSLSYIGEGAYGMVCAAFDNVKLVRVAIKKISPFEHQTYCQRTLREIKILLRFKH-ENIIGINDILRASTIDQMKDVYIVQDLMETDLYKLLKGQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNT-TCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNR-PLFPGKHYLDQLNHILGILGSPSQED----LDCIINMKARNYLQSLPPKAKVPWNRLFPKAD-----SKALDLLDKMLTFNPHRRITVEEALAHPYLEQY 327
BLAST of Casein kinase II subunit alpha vs. Ensembl Sea Lamprey
Match: cdk2 (cyclin-dependent kinase 2 [Source:ZFIN;Acc:ZDB-GENE-040426-2741]) HSP 1 Score: 122.865 bits (307), Expect = 1.044e-32 Identity = 86/300 (28.67%), Postives = 154/300 (51.33%), Query Frame = 3
Query: 156 DDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMK-----IKRELKILSNLRGCENIITLLNVVMDPISQTPSF-IFEYIENENFKELYKNFTKMDICY-----YLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLA-DFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
D + ++KIG G Y V+ T + +K ++ E + RE+ +L L NI+ LL+V+ S+T + +FE++ +++ K+ N + I Y+ QLL + CH+ +HRD+KPQN++IN ++L D+GLA F P + Y V + +++ PE+L+ + Y ++D+W++GC+ A M+ ++ +F G +DQL +I +TLGT + Q+ + + +P W + L+ LL +L++D R++AK AL+H FF
Sbjct: 2 DLFQKVEKIGEGTYGVVYKARHKMTGDTVALKKIRLDTETEGVPSTAIREIALLRELNH-PNIVRLLDVIH---SETKLYLVFEFL-DQDLKKYMDNAPPLGISLPLVKSYMHQLLQGIAFCHAQRTLHRDLKPQNLLINA-DGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGCKYYSTAVDVWSLGCIFAEMLTRR-ALFPGDSEIDQLFRIFRTLGTPDETVWQGITQLP------DYKPSFP--RWCAQDLTKVVPLLDAAGHDLLMQMLQYDPTRRVSAKAALNHHFF 286
BLAST of Casein kinase II subunit alpha vs. Ensembl Yeast
Match: CKA2 (Alpha' catalytic subunit of casein kinase 2 (CK2); CK2 is a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; protein abundance increases in response to DNA replication stress; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000005587]) HSP 1 Score: 342.813 bits (878), Expect = 1.598e-117 Identity = 172/321 (53.58%), Postives = 220/321 (68.54%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEY-NDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFAT 1025
S++RVY + + +P+ Y +Y + I + +Y II KIGRGKYSEVF G N+ VIKVLKPV KI RELKIL+NL G N++ L ++V D S+ P+ IFE I+N +F+ LY F DI YY QLL+ALD CHSMGIMHRDVKPQN++I+ + LRLIDWGLA+FYHP YNVRVASRY KGPELLVN YDYSLDLW+VGC+LA ++FKK+ F+G N DQL+KI LGT YL KY + L + N+ + + K W+ ++ +E + L E L+DNLLR+DHQ RLTAKEA+ H+FF T
Sbjct: 17 SVARVYKNACEERPQEYWDYEQGVTIDWGKISNYEIINKIGRGKYSEVFSGRCIVNNQKCVIKVLKPVKMKKIYRELKILTNLTGGPNVVGLYDIVQDADSKIPALIFEEIKNVDFRTLYPTFKLPDIQYYFTQLLIALDYCHSMGIMHRDVKPQNVMIDPTERKLRLIDWGLAEFYHPGVDYNVRVASRYHKGPELLVNLNQYDYSLDLWSVGCMLAAIVFKKEPFFKGSSNPDQLVKIATVLGTKELLGYLGKYGLHLPSEYDNIMRDFTKKSWTHFITSETK-LAVPEVVDLIDNLLRYDHQERLTAKEAMDHKFFKT 336
BLAST of Casein kinase II subunit alpha vs. Ensembl Yeast
Match: CKA1 (Alpha catalytic subunit of casein kinase 2 (CK2); a Ser/Thr protein kinase with roles in cell growth and proliferation; CK2, comprised of CKA1, CKA2, CKB1 and CKB2, has many substrates including transcription factors and all RNA polymerases; regulates Fkh1p-mediated donor preference during mating-type switching [Source:SGD;Acc:S000001297]) HSP 1 Score: 312.383 bits (799), Expect = 4.276e-105 Identity = 176/364 (48.35%), Postives = 240/364 (65.93%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQS-CDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNL--------------------------------------RGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVC-QESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+++NK + + Y +Y + I + + DY I K+GRGKYSEVF GV+ + IVIK+LKPV + KIKRE+KIL++L G NII L +++ DPIS+TP+ +FEY++N +F+ LY T ++I +Y+ +LL ALD CHSMGIMHRDVKP N++I+++ K LRLIDWGLA+FYH +YNVRVASR+FKGPELLV++ MYDYSLDLW+ G +LA MIFK++ F G N DQL+KIVK LGT+ FE YL KY+I L +E +Y KPW +++++ N+HL E L+DNLLR+DHQ RLTAKEA+ H +FA ++
Sbjct: 7 SEARVYTNINKQRTEEYWDYENTVIDWSTNTKDYEIENKVGRGKYSEVFQGVKLDSKVKIVIKMLKPVKKKKIKREIKILTDLSNEKVPPTTLPFQKDQYYTNQKEDVLKFIRPYIFDQPHNGHANIIHLFDIIKDPISKTPALVFEYVDNVDFRILYPKLTDLEIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHKNKKLRLIDWGLAEFYHVNMEYNVRVASRFFKGPELLVDYRMYDYSLDLWSFGTMLASMIFKREPFFHGTSNTDQLVKIVKVLGTSDFEKYLLKYEITLP-REFYDMDQYIRKPWHRFINDGNKHLSGNDEIIDLIDNLLRYDHQERLTAKEAMGHPWFAPIREQ 369
BLAST of Casein kinase II subunit alpha vs. Ensembl Yeast
Match: KSS1 (Mitogen-activated protein kinase (MAPK); involved in signal transduction pathways that control filamentous growth and pheromone response; regulates septum assembly, and may directly phosphorylate Bni4p; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains [Source:SGD;Acc:S000003272]) HSP 1 Score: 134.42 bits (337), Expect = 1.578e-36 Identity = 91/319 (28.53%), Postives = 162/319 (50.78%), Query Frame = 3
Query: 138 ITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAE----MKIKRELKILSNLRGCENIITLLNVVMDPIS---QTPSFIFEYIENENFKELYKN----FTKMD---ICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQK--------YNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
IT+ Y ++ IG G Y V + + + IK ++P ++ + RE+K+L ENII++L+ V P+S ++ E + + +++ N F+ + + Y+ Q+L AL HS ++HRD+KP N+++N+ L++ D+GLA VA+R+++ PE+++ F+ Y ++D+W+ GC+LA M+ K +F G+D QL I++ LGT SFE + + + ANL R P+ PW + + + LLD +L+F+ R++A EAL H + A +
Sbjct: 5 ITFDIPSQYKLVDLIGEGAYGTVCSAIHKPSGIKVAIKKIQPFSKKLFVTRTIREIKLLRYFHEHENIISILDKVR-PVSIDKLNAVYLVEELMETDLQKVINNQNSGFSTLSDDHVQYFTYQILRALKSIHSAQVIHRDIKPSNLLLNSNCD-LKVCDFGLARCLASSSDSRETLVGFMTEYVATRWYRAPEIMLTFQEYTTAMDIWSCGCILAEMVSGK-PLFPGRDYHHQLWLILEVLGTPSFEDFNQIKSKRAKEYIANLPMRPPL-PWETVWSKTD---LNPDMIDLLDKMLQFNPDKRISAAEALRHPYLAMY 316
BLAST of Casein kinase II subunit alpha vs. Ensembl Yeast
Match: HOG1 (Mitogen-activated protein kinase involved in osmoregulation; controls global reallocation of RNAPII during osmotic shock; mediates recruitment/activation of RNAPII at Hot1p-dependent promoters; binds calmodulin; stimulates antisense transcription to activate CDC28; defines novel S-phase checkpoint with Mrc1p that prevent replication/transcription conflicts; nuclear form represses pseudohyphal growth; autophosphorylates; protein abundance increases under DNA replication stress [Source:SGD;Acc:S000004103]) HSP 1 Score: 131.339 bits (329), Expect = 5.771e-35 Identity = 95/297 (31.99%), Postives = 160/297 (53.87%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIK-VLKP----VAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKN--FTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLK-EANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+ + +G G + V + T++ + IK ++KP V + RELK+L +LR EN+I L ++ + P+ F+ E ++ + L + K + Y+L Q+L L HS G++HRD+KP NI+IN L++ D+GLA P+ V++RY++ PE+++ ++ YD +D+W+ GC+ A MI K +F GKD+V Q I LG+ + + + LK +L R PI P+S E V ++ LL+ +L FD + R+TA +AL+H + A +
Sbjct: 23 YNDLNPVGMGAFGLVCSATDTLTSQPVAIKKIMKPFSTAVLAKRTYRELKLLKHLRH-ENLICLQDIFLSPLEDI-YFVTE-LQGTDLHRLLQTRPLEKQFVQYFLYQILRGLKYVHSAGVIHRDLKPSNILINENCD-LKICDFGLARIQDPQM--TGYVSTRYYRAPEIMLTWQKYDVEVDIWSAGCIFAEMIEGK-PLFPGKDHVHQFSIITDLLGSPP-KDVINTICSENTLKFVTSLPHRDPI-PFS-----ERFKTVEPDAVDLLEKMLVFDPKKRITAADALAHPYSAPY 305
BLAST of Casein kinase II subunit alpha vs. Ensembl Yeast
Match: PHO85 (Cyclin-dependent kinase; has ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle; human lissencephaly-associated homolog CDK5 functionally complements null mutation [Source:SGD;Acc:S000005952]) HSP 1 Score: 123.635 bits (309), Expect = 3.915e-33 Identity = 93/307 (30.29%), Postives = 161/307 (52.44%), Query Frame = 3
Query: 150 SCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIK----RELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMD---------ICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLA-DFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
S + ++K+G G Y+ V+ G+ +T + +K +K +E RE+ ++ L+ ENI+ L +V+ T +FE+++N+ K+ + T + + Y+ QLL L CH I+HRD+KPQN++IN R + L+L D+GLA F P ++ V + +++ P++L+ Y S+D+W+ GC+LA MI K +F G ++ +QL I +GT + ES L KL N+++R P + Q + + + L LL+ + RL+AK+AL H +FA +
Sbjct: 3 SSSQFKQLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELK-HENIVRLYDVIHTENKLT--LVFEFMDND-LKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQNLLINKRGQ-LKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMITGK-PLFPGTNDEEQLKLIFDIMGTPN-ES-LWPSVTKLPKYNPNIQQR-PPRDLRQVLQPHTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWFAEY 300
BLAST of Casein kinase II subunit alpha vs. Ensembl Nematostella
Match: EDO41552 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3V6]) HSP 1 Score: 345.51 bits (885), Expect = 9.040e-118 Identity = 176/320 (55.00%), Postives = 239/320 (74.69%), Query Frame = 3
Query: 60 TESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S +RVY+DVN +P+ Y +Y I + D+Y +++K+GRGKYSEVF + + + +V+K+LKPV + KIKRE+KIL NLRG NII LL+VV DP+S+TP+ IFEY+ N +FK+LY+ FT DI +YL +LL ALD CHS GIMHRDVKP N++I++ +TLRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+ + YDYSLD+W+ GC+LA MIF+K+ F G DN DQL++I K LGT Y++KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LLD LL++D Q R++AKEA+ H +F
Sbjct: 6 ASSRARVYADVNVHRPREYWDYESHVIEWGQQDNYELVRKLGRGKYSEVFEAINITNDEKVVVKILKPVKKKKIKREIKILQNLRGGVNIIDLLDVVKDPVSRTPALIFEYVNNTDFKQLYQTFTDFDIRFYLFELLKALDFCHSRGIMHRDVKPHNVMIDHDNRTLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDHQEYDYSLDMWSFGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLFDYIEKYHIELDPRFNDILGRHSKKRWERFVHSENQHLVSPEALDLLDRLLKYDIQERVSAKEAMDHPYF 325
BLAST of Casein kinase II subunit alpha vs. Ensembl Nematostella
Match: EDO26521 (pep supercontig:ASM20922v1:NEMVEscaffold_6854:158:6600:-1 gene:NEMVEDRAFT_v1g154013 transcript:EDO26521 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 140.969 bits (354), Expect = 1.516e-41 Identity = 62/96 (64.58%), Postives = 78/96 (81.25%), Query Frame = 3
Query: 558 LRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLN 845
+RLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+ + YDYSLD+W+ GC+LA MIF+K+ F G DN DQL++I K LGT Y++KY I+L+
Sbjct: 1 MRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDHQEYDYSLDMWSFGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLFDYIEKYHIELD 96
BLAST of Casein kinase II subunit alpha vs. Ensembl Nematostella
Match: EDO37435 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SFQ0]) HSP 1 Score: 142.51 bits (358), Expect = 2.589e-39 Identity = 96/304 (31.58%), Postives = 165/304 (54.28%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEM----KIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIF---EYIENENFKEL-YKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNV----RVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYV---DNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+ + IG G Y V GV+++T I IK + P + RE+KILS + ENII +L+++ P ++ I+ +E + +K L + + ICY+L Q+L L HS ++HRD+KP N+++N T L++ D+GLA P + VA+R+++ PE+++N + Y ++D+W+VGC+LA M+ + +F GK +DQL I+ LG+ + L IK N K + + P KP + ++ N + ++ L++NLL F+ R+T +EAL+H + +
Sbjct: 21 YTNLNYIGEGAYGMVVAGVDNTTGERIAIKKISPFEHQTYCQRTLREIKILSRFKH-ENIIGILDIIRAPRAEDMKDIYIVQPLMETDMYKLLKTQRLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNT-TCDLKICDFGLARIADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYSKAIDIWSVGCILAEMLANR-PLFPGKHYLDQLNLILNVLGSPIADDLL---CIK-NEKARSYLQSLPYKPKTPFIKLFSNAD-----AKALDLIENLLAFNPNKRITVEEALAHPYLEQY 312
BLAST of Casein kinase II subunit alpha vs. Ensembl Nematostella
Match: EDO46881 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RNM4]) HSP 1 Score: 131.724 bits (330), Expect = 3.946e-35 Identity = 96/332 (28.92%), Postives = 169/332 (50.90%), Query Frame = 3
Query: 105 PKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGV--------EDSTNRNIVIKVLKPV-AEMKIKR---ELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENF-KEL----------YKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFS 1031
P G+ ++ Y+ Y + IG G Y +V D N + K+ +P + M KR ELK+L ++R EN+I+LL+V T + FE+ ++ EL ++ + + + + Q+L L HS G++HRD+KP NI +N + L+++D+GLA + VA+R+++ PE+++N+ Y+ ++D+W+VGC++A ++ K T+F G D++DQL KI++ +G S + +L+K + Y P+ +Y N V LL+ +L D R+TA EALSH + A+++
Sbjct: 5 PPGFYRTELVNTVYEVPRKYQELSPIGTGAYGQVCSSTITEPDPTNPDGPNTVAIKKLSRPFQSTMHAKRTYRELKLLRHMRH-ENVISLLDVF------TTASAFEHFQDVYMVTELMGSDLNGILRFQKLSDEHVQFLVYQILRGLKYIHSAGVIHRDLKPSNIAVNEDCE-LKILDFGLARMTD--AEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTSK-TLFPGNDHIDQLTKIMQLVGKPS-DDFLQKIDSESARNYIAQMPDYRKTPFDEYFVGANPLAV-----DLLEKMLNLDTDHRITAVEALSHPYLASYA 319
BLAST of Casein kinase II subunit alpha vs. Ensembl Nematostella
Match: EDO48117 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RK70]) HSP 1 Score: 124.02 bits (310), Expect = 1.310e-32 Identity = 87/307 (28.34%), Postives = 156/307 (50.81%), Query Frame = 3
Query: 135 DITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLK----PVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENE--NFKELYKNFTKMD-ICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYH-PRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFS 1031
++ Y + Y+ + K+G G Y+ VF G T+ + +K ++ A RE+ +L L+ NI+TL + V S T +FEY+E + + + M+ + +L QLL LD CH ++HRD+KPQN++IN++ + L+L D+GLA P + Y+ V + +++ P++L+ Y +D+W VGC+ M + +F G D+LL I K LGT S E + ++ EA + ++P P + + + + LL+ L + + R++A +A+ H +F +
Sbjct: 2 ELGYGKMETYTKLDKLGEGTYATVFKGKSKLTDNIVALKEIRLEHEEGAPCTAIREVSLLKGLKHA-NIVTLHDTVHTQKSLT--LVFEYLEKDLKQYMDDCGGIMSMNNVRIFLFQLLRGLDYCHKRKVLHRDLKPQNLLINDKGE-LKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTAYSTQIDMWGVGCIFFEMATGR-PLFPGSTVEDELLLIFKVLGTPSEEVW-----PGISANEAFIAGKFPDYPRENLIIHAPR--LDNSGLELLEKFLEYTVKDRVSAHDAMRHDYFYSLG 296
BLAST of Casein kinase II subunit alpha vs. Ensembl Medaka
Match: csnk2a1 (casein kinase II subunit alpha [Source:NCBI gene;Acc:101156432]) HSP 1 Score: 356.681 bits (914), Expect = 2.268e-121 Identity = 174/318 (54.72%), Postives = 241/318 (75.79%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S SRVY DVN +P+ Y +Y + + + DDY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII+LL++V DP+S+TP+ +FE++ N +FK+LY+ + DI +Y+ ++L ALD CHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G DN DQL++I K LGT Y+ KY I+L+ + ++ R+ K W ++V +ENQHLV E+ LD LLR+DHQ RLTA+EA+ H +F
Sbjct: 7 SRSRVYPDVNTQRPREYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIISLLDIVKDPVSRTPALVFEHVNNTDFKQLYQTLSDFDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPNQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSTEALDFLDKLLRYDHQARLTAREAMDHPYF 324
BLAST of Casein kinase II subunit alpha vs. Ensembl Medaka
Match: CSNK2A2 (casein kinase 2 alpha 2 [Source:NCBI gene;Acc:101171988]) HSP 1 Score: 349.747 bits (896), Expect = 2.988e-119 Identity = 180/324 (55.56%), Postives = 240/324 (74.07%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S SRVY+DVN K + Y +Y + + +DY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FE I N +FKELY+ T DI +Y+ +LL ALD CHSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF+K+ F G+DN DQL++I K LGT YL+KY I+L+ + +L + K W Q+V ENQHLV E+ LLD LLR+DHQ RLTA EA+ H +F +E
Sbjct: 8 SKSRVYADVNTLKSREYWDYEAHVPNWNNQEDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGTNIIRLVDTVKDPVSRTPALVFECINNTDFKELYQKLTDYDIRFYMYELLKALDYCHSMGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFQKEPFFHGQDNYDQLVRIAKVLGTEELFGYLRKYHIELDPRFKDLLGQQSRKRWEQFVQTENQHLVSPEALDLLDKLLRYDHQQRLTATEAMEHPYFYPVVKE 331
BLAST of Casein kinase II subunit alpha vs. Ensembl Medaka
Match: csnk2a2a (casein kinase II subunit alpha' [Source:NCBI gene;Acc:101163644]) HSP 1 Score: 315.079 bits (806), Expect = 3.938e-105 Identity = 161/293 (54.95%), Postives = 219/293 (74.74%), Query Frame = 3
Query: 60 TESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQES 938
S +RVY+DVN K + Y +Y+ + + D+Y +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FEYI N +FKELY+ T DI +Y+ +LL ALD CHSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF K+ F G+DN DQL++I K LGT YL KY I+L+ + +L + K W Q++ +ENQHLV E+
Sbjct: 7 ASSKARVYTDVNTQKNREYWDYDAHVPNWSNQDNYQLVRKLGRGKYSEVFEAINVTNNEKVVVKILKPVKKKKIKREIKILENLRGGTNIIRLVDTVKDPVSRTPALVFEYINNTDFKELYQKLTDYDIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFLKEPFFHGQDNYDQLVRIAKVLGTDELYGYLHKYHIELDTRFKDLLGQQTRKRWEQFIQSENQHLVSPEA 299
BLAST of Casein kinase II subunit alpha vs. Ensembl Medaka
Match: CSNK2A2 (casein kinase 2 alpha 2 [Source:NCBI gene;Acc:101171988]) HSP 1 Score: 299.671 bits (766), Expect = 1.814e-99 Identity = 168/321 (52.34%), Postives = 222/321 (69.16%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQL---LKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFF 1019
S SRVY+DVN K + Y +Y + + +DY +++K+GRGKYSEVF + + N +V+K+LKPV + KIKRE+KIL NLRG NII L++ V DP+S+TP+ +FE I N +FKELY+ T DI +Y+ +LL ALD CHSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELL N + LD+W++GC+LA MIF+K+ F G+DN DQ+ V+ L S E++ L + R R K W Q+V ENQHLV E+ LLD LLR+DHQ RLTA EA+ H +F
Sbjct: 8 SKSRVYADVNTLKSREYWDYEAHVPNWNNQEDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGTNIIRLVDTVKDPVSRTPALVFECINNTDFKELYQKLTDYDIRFYMYELLKALDYCHSMGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPSQEYNVRVASRYFKGPELL-NIRI----LDMWSLGCMLASMIFQKEPFFHGQDNYDQVSENAAAVQVLWRFSVEAHFSA-AAPAGLTGCHFR-RQSRKRWEQFVQTENQHLVSPEALDLLDKLLRYDHQQRLTATEAMEHPYF 321
BLAST of Casein kinase II subunit alpha vs. Ensembl Medaka
Match: csnk2a2a (casein kinase II subunit alpha' [Source:NCBI gene;Acc:101163644]) HSP 1 Score: 296.59 bits (758), Expect = 3.667e-99 Identity = 148/326 (45.40%), Postives = 201/326 (61.66%), Query Frame = 3
Query: 60 TESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S +RVY+DVN K + Y +Y+ + + D+Y +++K+GRGKYSEVF + + N +V+K+L KELY+ T DI +Y+ +LL ALD CHSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELLV+++MYDYSLD+W++GC+LA MIF K+ F G+DN DQL++I K LGT YL KY I+L+ + +L + K W Q++ +ENQHLV E+ LLD LLR+DHQ RLTA EA+ H +F +E
Sbjct: 7 ASSKARVYTDVNTQKNREYWDYDAHVPNWSNQDNYQLVRKLGRGKYSEVFEAINVTNNEKVVVKIL---------------------------------------------------KELYQKLTDYDIRFYMFELLKALDYCHSMGIMHRDVKPHNVMIDHQLRKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFLKEPFFHGQDNYDQLVRIAKVLGTDELYGYLHKYHIELDTRFKDLLGQQTRKRWEQFIQSENQHLVSPEALDLLDKLLRYDHQQRLTAAEAMRHPYFYPVVKE 281
BLAST of Casein kinase II subunit alpha vs. Planmine SMEST
Match: SMESG000039019.1 (SMESG000039019.1) HSP 1 Score: 592.038 bits (1525), Expect = 0.000e+0 Identity = 292/327 (89.30%), Postives = 293/327 (89.60%), Query Frame = 3
Query: 57 MTESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
MTESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLK SQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHP+QKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE
Sbjct: 1 MTESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLK----------------------------------SQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPKQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 293
BLAST of Casein kinase II subunit alpha vs. Planmine SMEST
Match: SMESG000024545.1 (SMESG000024545.1) HSP 1 Score: 402.134 bits (1032), Expect = 4.877e-140 Identity = 183/324 (56.48%), Postives = 250/324 (77.16%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S SR+Y+D N ++PK Y Y+ ++ + S DDY I++KIGRGKYSEVF G+ STN +VIKVLKPV + KIKRE+KIL NL+GC NIITL ++V DP+S TP+ IFEY++N +FK+LY + DI +Y+ +LL AL+CCHSMGIMHRDVKP N++I+++ + LRLIDWGLA+FYHP ++YNVRVASRYFKGPELL++++MYDYSLD+W++GC+LA +IFKK+ F+G +N DQL +I K LGT +Y+ KY+I+L+ K + R+ K W ++V+ +NQHL+ E+ LD LLR+DHQ R+T+KEAL H +F T QE
Sbjct: 5 SKSRIYADANINRPKEYYSYHQTELEWGSPDDYQIVRKIGRGKYSEVFAGIRFSTNEEVVIKVLKPVKKDKIKREIKILQNLKGCINIITLEDIVRDPMSNTPALIFEYVDNTDFKDLYPTLSDYDIRFYIFELLKALNCCHSMGIMHRDVKPHNVMIDHQRRKLRLIDWGLAEFYHPGEEYNVRVASRYFKGPELLLDYQMYDYSLDMWSLGCMLASIIFKKEPFFRGHNNYDQLARIAKVLGTDDLYAYIHKYEIELDPKYNEILGRHSRKRWERFVNVDNQHLISNEALDFLDKLLRYDHQERITSKEALEHNYFYTIVQE 328
BLAST of Casein kinase II subunit alpha vs. Planmine SMEST
Match: SMESG000068560.1 (SMESG000068560.1) HSP 1 Score: 364.385 bits (934), Expect = 5.232e-125 Identity = 184/324 (56.79%), Postives = 244/324 (75.31%), Query Frame = 3
Query: 66 SLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEMKIKRELKILSNLRGCENIITLLNVVMDPISQTPSFIFEYIENENFKELYKNFTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATFSQE 1037
S SR+Y+DVN ++P+ Y +Y + +++ DDY I+KK+GRGKYSEVF GV TN VIKVLKPV + KIKRE+KIL NLRG NIITL VV DPIS+TP+ +FE++ N +FK+LY+ T DI YY+ +LL ALDCCHSMGIMHRDVKP N++I++ + LRLIDWGLA+FYHP Q+YNVRVASRYFKGPELL+++++YDYSLD+W++GC+ A MIF+K+ F G DN DQL++I K LGT Y+ KYQI+L+ + + R+ K W +++ +ENQHLV +S LD LL++DHQ RLTA+EA+ H +F QE
Sbjct: 5 SKSRIYADVNVNRPREYWDYEAYQVEWRNQDDYQIVKKLGRGKYSEVFEGVNVVTNEKCVIKVLKPVKKKKIKREIKILENLRGVPNIITLQAVVKDPISRTPALVFEHVNNIDFKQLYQTLTDYDIRYYIFELLKALDCCHSMGIMHRDVKPHNVMIDHEYRKLRLIDWGLAEFYHPAQEYNVRVASRYFKGPELLLDYQLYDYSLDMWSLGCMFASMIFRKEPFFHGHDNYDQLVRIAKVLGTDELYEYIHKYQIELDPRFNEILGRHSRKRWERFIHSENQHLVSADSLDFLDKLLQYDHQQRLTAREAMEHSYFFHIVQE 328
BLAST of Casein kinase II subunit alpha vs. Planmine SMEST
Match: SMESG000012868.1 (SMESG000012868.1) HSP 1 Score: 134.42 bits (337), Expect = 5.370e-36 Identity = 93/306 (30.39%), Postives = 162/306 (52.94%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEM----KIKRELKILSNLRGCENIITLLNVVMDPISQTPS----FIFEYIENENFKELYKN--FTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKYNVR----VASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRY---PIKPWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALSHRFFATF 1028
Y+ ++ IG G Y V ++ T+ ++ IK + P + RE+KIL + + EN+I + N+ + P S+ +I + + + + +L K+ + ICY+L Q+L + HS ++HRD+KP N+++N+ L++ D+GLA P Q +N VA+R+++ PE+++N + Y ++D+W++GC+LA M+ K +F GK V QL I LG+ +E K + + N K N ++ P +PW + N C +LD LL F+ RLTA +AL H + +
Sbjct: 21 YTNLRFIGEGAYGIVVSATDNVTHEDVAIKRISPFEHQTFCQRTYREIKILLHFKH-ENVIDIKNL-LTPASKIEDIKDIYIVQSLMDTDMYKLIKDQKLSNEHICYFLYQILRGVKYIHSANVLHRDLKPSNLLVNSNCD-LKICDFGLARVNDPVQDHNGMLTEYVATRWYRAPEVMLNSKGYSKAMDMWSIGCILAEMLGCK-PLFPGKHYVQQLKLIFDVLGSPDYED--KSWIV--NEKARNFVEKLIDIPKRPWEELFPNSEP--FC---LDILDQLLAFNPSKRLTADKALQHPYLQQY 313
BLAST of Casein kinase II subunit alpha vs. Planmine SMEST
Match: SMESG000032743.1 (SMESG000032743.1) HSP 1 Score: 127.102 bits (318), Expect = 3.708e-33 Identity = 91/297 (30.64%), Postives = 154/297 (51.85%), Query Frame = 3
Query: 162 YSIIKKIGRGKYSEVFLGVEDSTNRNIVIKVLKPVAEM----KIKRELKILSNLRGCENIITLLNVVM--DPISQTPSFIFEYIENENFKELYKN--FTKMDICYYLRQLLLALDCCHSMGIMHRDVKPQNIVINNRTKTLRLIDWGLADFYHPRQKY----NVRVASRYFKGPELLVNFEMYDYSLDLWAVGCVLAGMIFKKDTMFQGKDNVDQLLKIVKTLGTTSFESYLKKYQIKLNLKEANLRKRYPIK---PWSQYVDNENQHLVCQESFHLLDNLLRFDHQTRLTAKEALS 1007
Y K IG G Y +V ++ N N+ IK P + RE+KIL + ENII + N++ + I +I + + + +L K+ + ICY+L Q+L L HS ++HRD+KP N+++N+ L++ D+GL+ P + VA+R+++ PE+++N + Y ++D+W+VGC+LA M+ K +F GK V+QL I+ LG E K I +N K + +++ K PW Q N ++ + +L+ LL F+ RLT ++AL+
Sbjct: 21 YGNFKFIGEGAYGQVVSAIDTKDNSNVAIKRTSPFEHQTYCQRTYREIKILMHFNH-ENIIDIRNLLTAKEMIEMKDLYIVQALMETDLHKLCKSQKLSLEHICYFLYQILRGLKYIHSANVIHRDLKPSNLLVNSNCD-LKICDFGLSRVNDPEHDHKGILTEYVATRWYRAPEIMLNSKGYTKAIDIWSVGCILAEMLNGK-PIFPGKHYVEQLTLIITVLGYPCEED---KAWI-VNEKARHFVEKFVTKMKTPWKQLYPNADEQCIT-----MLEGLLTFNPGKRLTVEQALA 305 The following BLAST results are available for this feature:
BLAST of Casein kinase II subunit alpha vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of Casein kinase II subunit alpha vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034838 ID=SMED30034838|Name=Casein kinase II subunit alpha|organism=Schmidtea mediterranea sexual|type=transcript|length=1107bpback to top protein sequence of SMED30034838-orf-1 >SMED30034838-orf-1 ID=SMED30034838-orf-1|Name=SMED30034838-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=328bp MTESLSRVYSDVNKSKPKGYSEYNDLDITYQSCDDYSIIKKIGRGKYSEVback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
|
