LSM domain-containing protein 1-A

Overview
NameLSM domain-containing protein 1-A
Smed IDSMED30034773
Length (bp)449
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of LSM domain-containing protein 1-A (SMED30034773) t-SNE clustered cells

Violin plots show distribution of expression levels for LSM domain-containing protein 1-A (SMED30034773) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of LSM domain-containing protein 1-A (SMED30034773) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for LSM domain-containing protein 1-A (SMED30034773) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
Sort Descending | Sort Ascending | Only Non-Zero Values | Tile/Chart | Reset

Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034773

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 4

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
protonephridiaSMED30034773SMESG000070071.1 dd_Smed_v4_3800_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
nervous systemSMED30034773SMESG000070071.1 dd_Smed_v4_3800_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
parenchymal cellSMED30034773SMESG000070071.1 dd_Smed_v4_3800_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
muscle cellSMED30034773SMESG000070071.1 dd_Smed_v4_3800_0_1dd_Smed_v4PMID:29674431
Fincher et al., 2018		FACS sorted cell population asexual adult single-cell RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Human
Match: NAA38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212])

HSP 1 Score: 51.2174 bits (121), Expect = 9.783e-9
Identity = 22/74 (29.73%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  +T 
Sbjct:   22 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLTG 95
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Human
Match: NAA38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212])

HSP 1 Score: 51.2174 bits (121), Expect = 1.619e-8
Identity = 22/74 (29.73%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  +T 
Sbjct:   48 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLTG 121
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Human
Match: NAA38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212])

HSP 1 Score: 51.9878 bits (123), Expect = 2.018e-8
Identity = 22/74 (29.73%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  +T 
Sbjct:   96 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLTG 169
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Human
Match: NAA38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212])

HSP 1 Score: 49.2914 bits (116), Expect = 3.008e-8
Identity = 21/69 (30.43%), Postives = 39/69 (56.52%), Query Frame = 1 
Query:  166 LKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
            ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  +T 
Sbjct:    1 MRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLTG 69
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Human
Match: NAA38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:HGNC Symbol;Acc:HGNC:28212])

HSP 1 Score: 44.2838 bits (103), Expect = 8.538e-6
Identity = 24/84 (28.57%), Postives = 42/84 (50.00%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEY--PS--------PEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  PS        P +S      R +GL M+PG HI  + + +  +T 
Sbjct:   48 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSGQCPGNAHPPDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLTG 131
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Fly
Match: Sbat (gene:FBgn0051950 transcript:FBtr0077630)

HSP 1 Score: 46.9802 bits (110), Expect = 3.195e-7
Identity = 27/71 (38.03%), Postives = 39/71 (54.93%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKND 363
            +    L+I I+DGR++ G   CTD  ANIV+  C EY    E Q   L  N+   M+PG+HI  + + + D
Sbjct:   48 WLGRVLRIVITDGRVLVGFFNCTDRDANIVLSMCAEYLV--EGQEPRLLGNV---MVPGQHIVSLSIDEPD 113
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Fly
Match: Sbat (gene:FBgn0051950 transcript:FBtr0332457)

HSP 1 Score: 46.9802 bits (110), Expect = 3.195e-7
Identity = 27/71 (38.03%), Postives = 39/71 (54.93%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKND 363
            +    L+I I+DGR++ G   CTD  ANIV+  C EY    E Q   L  N+   M+PG+HI  + + + D
Sbjct:   48 WLGRVLRIVITDGRVLVGFFNCTDRDANIVLSMCAEYLV--EGQEPRLLGNV---MVPGQHIVSLSIDEPD 113
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Zebrafish
Match: naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:NCBI gene;Acc:335819])

HSP 1 Score: 49.2914 bits (116), Expect = 4.694e-8
Identity = 20/66 (30.30%), Postives = 37/66 (56.06%), Query Frame = 1 
Query:  148 DFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            +  N  ++I ++DGR + G  +CTD   N+++ +  E+    +S  +   R +GL MIPG H+  +
Sbjct:   30 NLLNKSMRIRMTDGRTLVGLFLCTDRDCNVILGSAQEFLKSTDSLSQGEPRVLGLAMIPGHHVVSI 95
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Mouse
Match: Naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:MGI Symbol;Acc:MGI:1925554])

HSP 1 Score: 50.447 bits (119), Expect = 2.591e-8
Identity = 21/74 (28.38%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  ++ 
Sbjct:   48 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLSG 121
[Close]
BLAST of LSM domain-containing protein 1-A vs. UniProt/SwissProt
Match: sp|Q9BRA0|LSMD1_HUMAN (N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA38 PE=1 SV=1)

HSP 1 Score: 51.2174 bits (121), Expect = 7.773e-8
Identity = 22/74 (29.73%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  +T 
Sbjct:   48 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLTG 121
[Close]
BLAST of LSM domain-containing protein 1-A vs. UniProt/SwissProt
Match: sp|Q9D2U5|LSMD1_MOUSE (N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Mus musculus OX=10090 GN=Naa38 PE=1 SV=1)

HSP 1 Score: 50.447 bits (119), Expect = 1.812e-7
Identity = 21/74 (28.38%), Postives = 40/74 (54.05%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++I ++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + + +  ++ 
Sbjct:   48 LLNKTMRIRMTDGRTLVGCFLCTDRDCNVILGSAQEFLKPSDSFSAGEPRVLGLAMVPGHHIVSIEVQRESLSG 121
[Close]
BLAST of LSM domain-containing protein 1-A vs. UniProt/SwissProt
Match: sp|A4IGZ4|LSMD1_XENTR (N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Xenopus tropicalis OX=8364 GN=naa38 PE=3 SV=2)

HSP 1 Score: 49.6766 bits (117), Expect = 2.448e-7
Identity = 24/74 (32.43%), Postives = 41/74 (55.41%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++IE++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + +    VT+
Sbjct:   36 LLNRNMRIEMTDGRSLIGCFLCTDRDCNVILGSAQEFLRPSDSFPVREPRVLGLAMVPGHHIVSIQVELESVTS 109
[Close]
BLAST of LSM domain-containing protein 1-A vs. UniProt/SwissProt
Match: sp|Q6GQ67|LMD1A_XENLA (N-alpha-acetyltransferase 38-A, NatC auxiliary subunit OS=Xenopus laevis OX=8355 GN=naa38-a PE=3 SV=1)

HSP 1 Score: 49.6766 bits (117), Expect = 2.956e-7
Identity = 24/74 (32.43%), Postives = 41/74 (55.41%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
              N  ++IE++DGR + G  +CTD   N+++ +  E+  P +S      R +GL M+PG HI  + +    VT+
Sbjct:   36 LLNRNMRIEMTDGRSLIGCFLCTDRDCNVILGSAQEFLRPSDSFPVREPRVLGLAMVPGHHIVSIQVELESVTS 109
[Close]
BLAST of LSM domain-containing protein 1-A vs. UniProt/SwissProt
Match: sp|A2BIG9|LSMD1_DANRE (N-alpha-acetyltransferase 38, NatC auxiliary subunit OS=Danio rerio OX=7955 GN=naa38 PE=3 SV=1)

HSP 1 Score: 49.2914 bits (116), Expect = 3.543e-7
Identity = 20/66 (30.30%), Postives = 37/66 (56.06%), Query Frame = 1 
Query:  148 DFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            +  N  ++I ++DGR + G  +CTD   N+++ +  E+    +S  +   R +GL MIPG H+  +
Sbjct:   30 NLLNKSMRIRMTDGRTLVGLFLCTDRDCNVILGSAQEFLKSTDSLSQGEPRVLGLAMIPGHHVVSI 95
[Close]
BLAST of LSM domain-containing protein 1-A vs. TrEMBL
Match: A0A443S516 (LSM domain-containing protein 1-like protein OS=Leptotrombidium deliense OX=299467 GN=B4U80_01441 PE=4 SV=1)

HSP 1 Score: 75.485 bits (184), Expect = 4.007e-15
Identity = 29/65 (44.62%), Postives = 45/65 (69.23%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            + N  +KIE+SDGR++ G  +CTDCH N+++ +C+EY  P+E  Y    R +GL M+PG+HI  +
Sbjct:    5 WLNKNMKIEMSDGRVLIGIFLCTDCHQNVILGSCMEYVKPDEDGYTEDARALGLAMVPGQHIVSI 69
[Close]
BLAST of LSM domain-containing protein 1-A vs. TrEMBL
Match: A0A443R1X7 (LSM domain-containing protein 1-like protein OS=Dinothrombium tinctorium OX=1965070 GN=B4U79_01643 PE=4 SV=1)

HSP 1 Score: 73.9442 bits (180), Expect = 1.537e-14
Identity = 28/65 (43.08%), Postives = 45/65 (69.23%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            + N  +KIE++DGR++ G  +CTDCH N+++ +CVEY  P++  Y    R +GL M+PG+HI  +
Sbjct:    8 WLNKNMKIEMTDGRVLIGIFLCTDCHQNVILGSCVEYVKPDDDGYTEDARALGLAMVPGQHIVSI 72
[Close]
BLAST of LSM domain-containing protein 1-A vs. TrEMBL
Match: A0A1S8WYI9 (LSM domain protein OS=Opisthorchis viverrini OX=6198 GN=X801_04535 PE=4 SV=1)

HSP 1 Score: 72.0182 bits (175), Expect = 1.390e-13
Identity = 31/60 (51.67%), Postives = 44/60 (73.33%), Query Frame = 1 
Query:  166 LKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            L + ++DGR   G L CTD  AN+V+ +CVEYPSP +S Y++  RN+  ++IPG+HITKV
Sbjct:   28 LTVHVTDGRRFVGQLWCTDSAANLVLGSCVEYPSPSDSFYDDSRRNLMAVVIPGQHITKV 87
[Close]
BLAST of LSM domain-containing protein 1-A vs. TrEMBL
Match: A0A419Q9U1 (N-alpha-acetyltransferase 38 OS=Clonorchis sinensis OX=79923 GN=Naa38 PE=4 SV=1)

HSP 1 Score: 73.559 bits (179), Expect = 4.375e-13
Identity = 32/60 (53.33%), Postives = 44/60 (73.33%), Query Frame = 1 
Query:  166 LKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            L + ++DGR   G L CTD  AN+V+ +CVEYPSP +S Y+N  RN+  ++IPG+HITKV
Sbjct:  151 LTVHVTDGRRFVGQLWCTDSAANLVLGSCVEYPSPSDSFYDNSRRNLMAVVIPGQHITKV 210
[Close]
BLAST of LSM domain-containing protein 1-A vs. TrEMBL
Match: A0A0P4VL70 (Putative u1 snrnp component OS=Rhodnius neglectus OX=72488 PE=2 SV=1)

HSP 1 Score: 70.0922 bits (170), Expect = 2.938e-12
Identity = 33/88 (37.50%), Postives = 55/88 (62.50%), Query Frame = 1 
Query:   91 CSNNQLKTDNNYEI-NSAFGDFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLL 351
            C+  Q + D+  +   S   ++ N  LKIE+SDGRI+ G+ +CTD  AN+++  C E+ +PE   + +  R +GL+M+PG+HI  + L
Sbjct:   46 CAEPQQQVDSTEKTGKSKLQNWLNKSLKIEMSDGRILIGNFLCTDRDANVILGACTEFLNPEVCGFSDEPRILGLVMVPGRHIVSMHL 133
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Cavefish
Match: naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:NCBI gene;Acc:335819])

HSP 1 Score: 48.521 bits (114), Expect = 6.000e-8
Identity = 20/66 (30.30%), Postives = 37/66 (56.06%), Query Frame = 1 
Query:  148 DFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            +  N  ++I ++DGR + G  +CTD   N+++ +  E+    +S  +   R +GL MIPG H+  +
Sbjct:   27 NLLNKSMRIRMTDGRTLVGLFLCTDRDCNVILGSAQEFLKSTDSFSQGEPRVLGLAMIPGHHVVSI 92
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Cavefish
Match: naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:NCBI gene;Acc:335819])

HSP 1 Score: 48.1358 bits (113), Expect = 1.069e-7
Identity = 20/66 (30.30%), Postives = 37/66 (56.06%), Query Frame = 1 
Query:  148 DFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            +  N  ++I ++DGR + G  +CTD   N+++ +  E+    +S  +   R +GL MIPG H+  +
Sbjct:   36 NLLNKSMRIRMTDGRTLVGLFLCTDRDCNVILGSAQEFLKSTDSFSQGEPRVLGLAMIPGHHVVSI 101
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Sea Lamprey
Match: naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:NCBI gene;Acc:335819])

HSP 1 Score: 53.5286 bits (127), Expect = 1.795e-10
Identity = 24/70 (34.29%), Postives = 38/70 (54.29%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKN 360
            + N  +KI +SDGR + G  +CTD   N+++ +  EY    E   +   R +GL M+PG HI  + +  N
Sbjct:   24 WLNRSMKIRMSDGRTLVGSFLCTDRDCNVILGSAQEYLKGTEPSSQGEARVLGLAMVPGHHILSIEVETN 93
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Nematostella
Match: EDO28101 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7F0])

HSP 1 Score: 46.595 bits (109), Expect = 7.841e-8
Identity = 22/66 (33.33%), Postives = 38/66 (57.58%), Query Frame = 1 
Query:  151 FFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLT-RNIGLLMIPGKHITKV 345
            + N  ++++ISDGR + G  +CTD   NI++ +C E+        +    R +GL M+PG+HI  +
Sbjct:    7 WLNKLMRVKISDGRTLIGSFLCTDKDRNIILGSCQEFSLLLSLGVDKEDPRILGLAMVPGRHIQSI 72
[Close]
BLAST of LSM domain-containing protein 1-A vs. Ensembl Medaka
Match: naa38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit [Source:NCBI gene;Acc:101167827])

HSP 1 Score: 46.2098 bits (108), Expect = 7.871e-7
Identity = 20/84 (23.81%), Postives = 41/84 (48.81%), Query Frame = 1 
Query:   94 SNNQLKTDNNYEINSAFGDFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKV 345
            +  Q +   + +         N  ++I ++DGR + G  +CTD   N+++ +  E+    ++  +   R +GL MIPG H+  +
Sbjct:   34 TRGQTEVPPSSQARQKLEGLLNKNMRIRMTDGRTLVGLFLCTDRDCNVILGSAQEFLKSPDTFSQGEPRVLGLAMIPGHHVVSI 117
[Close]
BLAST of LSM domain-containing protein 1-A vs. Planmine SMEST
Match: SMESG000070071.1 (SMESG000070071.1)

HSP 1 Score: 202.216 bits (513), Expect = 2.206e-68
Identity = 97/97 (100.00%), Postives = 97/97 (100.00%), Query Frame = 1 
Query:   82 MSLCSNNQLKTDNNYEINSAFGDFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
            MSLCSNNQLKTDNNYEINSAFGDFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN
Sbjct:    1 MSLCSNNQLKTDNNYEINSAFGDFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 97
[Close]
BLAST of LSM domain-containing protein 1-A vs. Planmine SMEST
Match: SMESG000070071.1 (SMESG000070071.1)

HSP 1 Score: 150.984 bits (380), Expect = 1.939e-48
Identity = 78/97 (80.41%), Postives = 78/97 (80.41%), Query Frame = 1 
Query:   82 MSLCSNNQLKTDNNYEINSAFGDFFNYPLKIEISDGRIVKGHLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 372
            MSLCSNNQLKTDNNYEINSAFG                   HLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN
Sbjct:    1 MSLCSNNQLKTDNNYEINSAFG-------------------HLICTDCHANIVMRNCVEYPSPEESQYENLTRNIGLLMIPGKHITKVLLCKNDVTN 78
The following BLAST results are available for this feature:
BLAST of LSM domain-containing protein 1-A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
NAA389.783e-929.73N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
NAA381.619e-829.73N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
NAA382.018e-829.73N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
NAA383.008e-830.43N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
NAA388.538e-628.57N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
Sbat3.195e-738.03gene:FBgn0051950 transcript:FBtr0077630[more]
Sbat3.195e-738.03gene:FBgn0051950 transcript:FBtr0332457[more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 1
Match NameE-valueIdentityDescription
naa384.694e-830.30N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 1
Match NameE-valueIdentityDescription
Naa382.591e-828.38N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
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BLAST of LSM domain-containing protein 1-A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q9BRA0|LSMD1_HUMAN7.773e-829.73N-alpha-acetyltransferase 38, NatC auxiliary subun... [more]
sp|Q9D2U5|LSMD1_MOUSE1.812e-728.38N-alpha-acetyltransferase 38, NatC auxiliary subun... [more]
sp|A4IGZ4|LSMD1_XENTR2.448e-732.43N-alpha-acetyltransferase 38, NatC auxiliary subun... [more]
sp|Q6GQ67|LMD1A_XENLA2.956e-732.43N-alpha-acetyltransferase 38-A, NatC auxiliary sub... [more]
sp|A2BIG9|LSMD1_DANRE3.543e-730.30N-alpha-acetyltransferase 38, NatC auxiliary subun... [more]
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BLAST of LSM domain-containing protein 1-A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A443S5164.007e-1544.62LSM domain-containing protein 1-like protein OS=Le... [more]
A0A443R1X71.537e-1443.08LSM domain-containing protein 1-like protein OS=Di... [more]
A0A1S8WYI91.390e-1351.67LSM domain protein OS=Opisthorchis viverrini OX=61... [more]
A0A419Q9U14.375e-1353.33N-alpha-acetyltransferase 38 OS=Clonorchis sinensi... [more]
A0A0P4VL702.938e-1237.50Putative u1 snrnp component OS=Rhodnius neglectus ... [more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 2
Match NameE-valueIdentityDescription
naa386.000e-830.30N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
naa381.069e-730.30N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1
Match NameE-valueIdentityDescription
naa381.795e-1034.29N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0
Match NameE-valueIdentityDescription
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1
Match NameE-valueIdentityDescription
EDO281017.841e-833.33Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of LSM domain-containing protein 1-A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 1
Match NameE-valueIdentityDescription
naa387.871e-723.81N(alpha)-acetyltransferase 38, NatC auxiliary subu... [more]
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BLAST of LSM domain-containing protein 1-A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2
Match NameE-valueIdentityDescription
SMESG000070071.12.206e-68100.00SMESG000070071.1[more]
SMESG000070071.11.939e-4880.41SMESG000070071.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034773 ID=SMED30034773|Name=LSM domain-containing protein 1-A|organism=Schmidtea mediterranea sexual|type=transcript|length=449bp
ATTTTAATTTTTATATACTGTGTTTTAATAATGTAATGTATTGCAATCTT
TAATGTAAATTTTAAATTTATTTAGTCCAAAATGAGTTTATGCAGCAATA
ATCAATTAAAAACTGACAATAATTACGAAATTAATAGCGCTTTTGGTGAT
TTTTTTAATTATCCACTTAAAATTGAAATTTCTGATGGTCGAATCGTTAA
AGGTCATTTAATTTGCACAGATTGCCATGCGAACATTGTTATGAGGAATT
GTGTTGAATATCCAAGCCCAGAAGAATCTCAATACGAAAACTTAACAAGA
AATATTGGACTTTTAATGATACCTGGCAAACATATTACGAAAGTGTTATT
ATGTAAAAATGATGTTACCAACTGATGTAAATGAGATAAATAATTTTTAA
GAAAACATTAGTTTTATCAAATAAAATGATTACTTCTTTGTTTTTAATG
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000020protonephridia
Vocabulary: INTERPRO
TermDefinition
IPR034110LSMD1
IPR001163LSM_dom_euk/arc
IPR010920LSM_dom_sf
Vocabulary: cellular component
TermDefinition
GO:0031417NatC complex
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001163LSM domain, eukaryotic/archaea-typeSMARTSM00651Sm3coord: 19..90
e-value: 4.3E-8
score: 42.9
IPR001163LSM domain, eukaryotic/archaea-typePFAMPF01423LSMcoord: 25..86
e-value: 3.7E-10
score: 39.3
NoneNo IPR availableGENE3DG3DSA:2.30.30.100coord: 18..95
e-value: 8.9E-18
score: 65.9
NoneNo IPR availablePANTHERPTHR10701SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND Ncoord: 25..90
IPR034110LSM domain containing 1PANTHERPTHR10701:SF5N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNITcoord: 25..90
IPR034110LSM domain containing 1CDDcd06168LSMD1coord: 23..88
e-value: 2.51237E-24
score: 85.3013
IPR010920LSM domain superfamilySUPERFAMILYSSF50182Sm-like ribonucleoproteinscoord: 20..92