Dynamin-type G domain-containing protein

Overview


Name	Dynamin-type G domain-containing protein
Smed ID	SMED30034752
Length (bp)	1968

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of Dynamin-type G domain-containing protein (SMED30034752) t-SNE clustered cells

Violin plots show distribution of expression levels for Dynamin-type G domain-containing protein (SMED30034752) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Dynamin-type G domain-containing protein (SMED30034752) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Dynamin-type G domain-containing protein (SMED30034752) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034752

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication
nervous system	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
pharynx	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
nervous system	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
gut	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
epidermis	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
cephalic ganglia	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
neuron	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parapharyngeal region	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchyma	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
parenchymal cell	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
non-ciliated neuron	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034752	SMESG000014762.1 SMESG000014753.1	Contig44169	newmark_ests	PMID:29674431 Fincher et al., 2018
Smed sexual biotype	SMED30034752	SMESG000014762.1 SMESG000014753.1	Contig44169	uc_Smed_v2	PMID:29674431 Fincher et al., 2018
dorsal-ventral muscle cell	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:30471994 Scimone et al., 2018
epidermis	SMED30034752	SMESG000014762.1 SMESG000014753.1	dd_Smed_v4_2080_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017
epidermis	SMED30034752	SMESG000014753.1	dd_Smed_v4_2409_0_1	dd_Smed_v4	PMID:28292427 Wurtzel et al., 2017

Note: Hover over icons to view figure legend

Homology

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 96.2857 bits (238), Expect = 8.071e-21
Identity = 75/303 (24.75%), Postives = 146/303 (48.18%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            K  +I E ++R  +K+  FG+ S GKS ++NAML D    S   H T+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+   R +    + +S   + +    R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:   63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVN 359

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN1 (mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262])

HSP 1 Score: 97.4413 bits (241), Expect = 2.207e-20
Identity = 75/303 (24.75%), Postives = 146/303 (48.18%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            K  +I E ++R  +K+  FG+ S GKS ++NAML D    S   H T+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+   R +    + +S   + +    R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:   63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVN 359

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Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            K  +I E ++R  +K+  FG+ S GKS ++NAML D    S   H T+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+   R +    + +S   + +    R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:   63 KLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVRVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVN 359

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Match: MFN2 (mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877])

HSP 1 Score: 96.2857 bits (238), Expect = 5.125e-20
Identity = 69/274 (25.18%), Postives = 135/274 (49.27%), Query Frame = 1

Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++               +++ +  + + +++  +  +K   A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ +  + E C+ FL  +L +    +  DRI+F+SA+E+   RI+    + +    + + F+    +F  FE   ++ I+
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHE-----AFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECIS 350

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Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++               +++ +  + + +++  +  +K   A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ +  + E C+ FL  +L +    +  DRI+F+SA+E+   RI+    + +    + + F+    +F  FE   ++ I+
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVEGTDGHE-----AFLLTEGSEEKRSAKTVNQLAHALHQDKQLHAGSLVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKHFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRSQAGDRIFFVSAKEVLNARIQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECIS 350

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Match: fzo-1 (Transmembrane GTPase fzo-1 [Source:UniProtKB/Swiss-Prot;Acc:Q23424])

HSP 1 Score: 85.5001 bits (210), Expect = 5.511e-17
Identity = 67/259 (25.87%), Postives = 116/259 (44.79%), Query Frame = 1

Query:  223 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKG--NKATANETIEVSICMDDETL---------------LKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRI 942
            +++ I    + I +   RD +K+  FG+ S GKS  +NAML +        HTT  F+ V+ SE +                 +  +  ++I   + G    A ++E  ++     D  L               L+  + I+D PG     +    I K+  +AD+F+ V N    LT  ++ FF       +KP+VFI+ N+WD S  + E    + K  +       + +LE+  E E+ DRI+F+S+RE+ + R+
Sbjct:   81 EIEAIGDSIKTIMDTFQRDNMKVVFFGRTSNGKSTTINAMLHEKVLPQGMGHTTCCFLQVEGSEGE-------------VGHLQLDDNPQKIDMKMLGKIGHALSDENSDLPAMGQDSLLKVFHPKKSESGECRLLQNDVVILDSPGVDLSPEFDSWIDKHCLDADVFVLVSNAESTLTQAEKNFFLRVAKKLSKPNVFILNNRWDASAAETENIEDVKKQHLTRFRQFLVDELEVCSEREVNDRIFFVSSREVLESRL 326

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: fzo (gene:FBgn0011596 transcript:FBtr0084399)

HSP 1 Score: 113.235 bits (282), Expect = 9.962e-26
Identity = 74/278 (26.62%), Postives = 137/278 (49.28%), Query Frame = 1

Query:  226 LDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFV-----------HVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEI-TKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFE 1014
            L    S+ E I + ++RD +K+  FG+ S GKS ++NA+L +    SA  HTTS F            HVK  ++D +                 +  + +++          +  ++V++  +  ++L   + ++D PG    +Q+ DC+     +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD++ + + E  Q  K +  E C   L  +L + +   E ++RIY +SA E   IR   N  + +     ++R+++F+RFE
Sbjct:   68 LCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEH---------------MELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR---NGQITNPSGQTQQRYQEFLRFE 327

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0343373)

HSP 1 Score: 109.383 bits (272), Expect = 2.224e-24
Identity = 79/276 (28.62%), Postives = 139/276 (50.36%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDE-ESTQMSKTKIK--EECSKFLRK-LEITKEDEIYDRIYFLSAREMSQIRIE----NNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN 1038
            K   I E + RD +K+  FG+ S GKS ++NAML +    S   HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+ E + ++++K K +  E C  FL K L+++ E E  +R++F+SARE  Q RIE    N   +       + R+ +F  FE   ++ I+
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESELAKVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECIS 394

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070910)

HSP 1 Score: 108.227 bits (269), Expect = 4.421e-24
Identity = 78/273 (28.57%), Postives = 135/273 (49.45%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRK-LEITKEDEIYDRIYFLSAREMSQIRIE----NNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN 1038
            K   I E + RD +K+  FG+ S GKS ++NAML +    S   HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+  E  +  K++  E C  FL K L+++ E E  +R++F+SARE  Q RIE    N   +       + R+ +F  FE   ++ I+
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEP-ECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECIS 390

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Match: Marf (gene:FBgn0029870 transcript:FBtr0070909)

HSP 1 Score: 108.227 bits (269), Expect = 4.421e-24
Identity = 78/273 (28.57%), Postives = 135/273 (49.45%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRK-LEITKEDEIYDRIYFLSAREMSQIRIE----NNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN 1038
            K   I E + RD +K+  FG+ S GKS ++NAML +    S   HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+  E  +  K++  E C  FL K L+++ E E  +R++F+SARE  Q RIE    N   +       + R+ +F  FE   ++ I+
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEP-ECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECIS 390

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 98.9821 bits (245), Expect = 5.405e-21
Identity = 88/343 (25.66%), Postives = 166/343 (48.40%), Query Frame = 1

Query:   64 PETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFS-------SKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFED----FMRFEYNLKKYIN 1038
            P  LK+    +K +SE+     +   + CE             VK+T  N S        +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K    + C  FL  +L++    +  +RI+F+SA+E+   R++    + ++   + + F+D    F  FE + ++ I+
Sbjct:    6 PSPLKRFVLAKKKISEVFEQLLVYVQEGCEF------------VKETCANESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQH-TDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFERSFEECIS 330

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Query:   64 PETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFS-------SKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFED----FMRFEYNLKKYIN 1038
            P  LK+    +K +SE+     +   + CE             VK+T  N S        +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K    + C  FL  +L++    +  +RI+F+SA+E+   R++    + ++   + + F+D    F  FE + ++ I+
Sbjct:    6 PSPLKRFVLAKKKISEVFEQLLVYVQEGCEF------------VKETCANESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQH-TDRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQNFERSFEECIS 330

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 95.5153 bits (236), Expect = 5.909e-21
Identity = 84/329 (25.53%), Postives = 160/329 (48.63%), Query Frame = 1

Query:   64 PETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFS-------SKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMR 1008
            P  LK+    +K +SE+     +   + CE             VK+T  N S        +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K    + C  FL  +L++    +  +RI+F+SA+E+   R++    + ++   + + F+D ++
Sbjct:    6 PSPLKRFVLAKKKISEVFEQLLVYVQEGCEF------------VKETCANESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHT-DRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLK 316

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn1b (mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553])

HSP 1 Score: 93.9745 bits (232), Expect = 1.670e-20
Identity = 87/331 (26.28%), Postives = 161/331 (48.64%), Query Frame = 1

Query:   64 PETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFS-------SKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREM--SQIRIENNDSLVDSDPNVKKRFEDFMR 1008
            P  LK+    +K +SE+     +   + CE             VK+T  N S        +LD IES   K  +I E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ +++D             +++ K I+ + +++  +  +++  A   ++V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S  + E    + K    + C  FL  +L++    +  +RI+F+SA+E+  S+++     +L +   +  K F++F R
Sbjct:    6 PSPLKRFVLAKKKISEVFEQLLVYVQEGCEF------------VKETCANESLENIANKDQLDEIESYTSKLSIIQEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDK-----AFLKTEGSEEEKSIKTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNEKLSKPNIFILNNRWDASAAEPEYMEDVRKQHT-DRCVNFLVEELKVVDRAQAPNRIFFVSAKEVLNSRMQRAQGGALAEGFQDRLKEFQNFER 318

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 95.9005 bits (237), Expect = 4.826e-20
Identity = 69/263 (26.24%), Postives = 133/263 (50.57%), Query Frame = 1

Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEY 1017
            SK   I E ++R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ +             +D+ K ++ + +++  +  ++   A   + V        LL+  + +VD PG    +++   I K   +AD+F+ V N    L   ++ FF    +  + P++FI+ N+WD S N+ E   ++ +  + + C+ FL  +L +       DRI+F+SA+E+ Q R++    + ++   + + F+  M FE+
Sbjct:   83 SKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNE-----SFLLTEGSDERKSVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASANEPEYMEEVRRQHM-DRCTSFLVDELRVVDRSHAGDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARM-FEF 338

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 96.2857 bits (238), Expect = 5.428e-20
Identity = 72/272 (26.47%), Postives = 136/272 (50.00%), Query Frame = 1

Query:  223 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFE 1014
            K+   ++K   I E + R  +K+  FG+ S GKS ++N+ML D    S   HTT+ F+ V+ +E D             +++ K ++ + +++  +  +K   A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K  + E C  FL  +L++    E   RI+F+SA+E+   R+     + ++   + +    RF +F +FE
Sbjct:   75 KVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDK-----AYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFE 340

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 95.9005 bits (237), Expect = 6.253e-20
Identity = 72/272 (26.47%), Postives = 136/272 (50.00%), Query Frame = 1

Query:  223 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFE 1014
            K+   ++K   I E + R  +K+  FG+ S GKS ++N+ML D    S   HTT+ F+ V+ +E D             +++ K ++ + +++  +  +K   A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K  + E C  FL  +L++    E   RI+F+SA+E+   R+     + ++   + +    RF +F +FE
Sbjct:   67 KVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDK-----AYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFE 332

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Query:  223 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFE 1014
            K+   ++K   I E + R  +K+  FG+ S GKS ++N+ML D    S   HTT+ F+ V+ +E D             +++ K ++ + +++  +  +K   A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K  + E C  FL  +L++    E   RI+F+SA+E+   R+     + ++   + +    RF +F +FE
Sbjct:   72 KVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGDK-----AYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFE 337

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 95.9005 bits (237), Expect = 6.931e-20
Identity = 72/272 (26.47%), Postives = 136/272 (50.00%), Query Frame = 1

Query:  223 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFE 1014
            K+   ++K   I E + R  +K+  FG+ S GKS ++N+ML D    S   HTT+ F+ V+ +E D             +++ K ++ + +++  +  +K   A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K  + E C  FL  +L++    E   RI+F+SA+E+   R+     + ++   + +    RF +F +FE
Sbjct:   72 KVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGD-----KAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFE 337

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Match: mfn1 (mitofusin 1 [Source:NCBI gene;Acc:548943])

HSP 1 Score: 95.9005 bits (237), Expect = 6.994e-20
Identity = 72/272 (26.47%), Postives = 136/272 (50.00%), Query Frame = 1

Query:  223 KLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFE 1014
            K+   ++K   I E + R  +K+  FG+ S GKS ++N+ML D    S   HTT+ F+ V+ +E D             +++ K ++ + +++  +  +K   A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K  + E C  FL  +L++    E   RI+F+SA+E+   R+     + ++   + +    RF +F +FE
Sbjct:   57 KVKASKTKLAGIGEVLARRNMKVAFFGRTSSGKSTVINSMLWDKVLPSGIGHTTNCFLSVEGTEGD-----KAYLMTEGSEEKKSVKTVNQLAHALHMDKDLGAGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFYKVNEKLSKPNIFILNNRWDASASEPEYMEDVRKQHM-ERCQSFLVDELKVVDSLEAQKRIFFVSAKEVLNARMHKAQGMPEAGAALAEGFHTRFLEFQKFE 322

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn1 (mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664])

HSP 1 Score: 100.138 bits (248), Expect = 2.141e-21
Identity = 95/382 (24.87%), Postives = 176/382 (46.07%), Query Frame = 1

Query:   61 LPETLKQLKNI---RKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIES------------KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREM-------SQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            + ET+  LK+    +K ++ I       +G++ E      +TE    V+ T  N   +LD I S            K  VI E ++R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+       +Q   E   +L +     + R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:    1 MAETVSPLKHFVLAKKAITAI-------FGQLLEF-----VTEGSHFVEATYRN--PELDRIASEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAE---GFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVN 359

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Query:   61 LPETLKQLKNI---RKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIES------------KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREM-------SQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            + ET+  LK+    +K ++ I       +G++ E      +TE    V+ T  N   +LD I S            K  VI E ++R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+       +Q   E   +L +     + R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:    1 MAETVSPLKHFVLAKKAITAI-------FGQLLEF-----VTEGSHFVEATYRN--PELDRIASEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAE---GFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVN 359

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Match: Mfn2 (mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230])

HSP 1 Score: 93.9745 bits (232), Expect = 1.826e-19
Identity = 69/273 (25.27%), Postives = 129/273 (47.25%), Query Frame = 1

Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ +  + E C+ FL  +L +    +  DRI+F+SA+E+   R++    + +    + + F+    +F  FE   ++ I+
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECIS 350

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Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ +  + E C+ FL  +L +    +  DRI+F+SA+E+   R++    + +    + + F+    +F  FE   ++ I+
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECIS 350

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Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK  + ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ +  + E C+ FL  +L +    +  DRI+F+SA+E+   R++    + +    + + F+    +F  FE   ++ I+
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSMVSVMWPNSKCPLLKDDLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERQFEECIS 350

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|O18412|FZO_DROME (Transmembrane GTPase fzo OS=Drosophila melanogaster OX=7227 GN=fzo PE=1 SV=2)

HSP 1 Score: 113.235 bits (282), Expect = 9.986e-25
Identity = 74/278 (26.62%), Postives = 137/278 (49.28%), Query Frame = 1

Query:  226 LDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFV-----------HVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEI-TKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFE 1014
            L    S+ E I + ++RD +K+  FG+ S GKS ++NA+L +    SA  HTTS F            HVK  ++D +                 +  + +++          +  ++V++  +  ++L   + ++D PG    +Q+ DC+     +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD++ + + E  Q  K +  E C   L  +L + +   E ++RIY +SA E   IR   N  + +     ++R+++F+RFE
Sbjct:   68 LCAFSSRVEAIAKVLSRDRMKVAFFGRTSNGKSAVINALLHEKILPSAMGHTTSCFCQVQANGSNETEHVKVEQEDEH---------------MELSALSQLASAHSPGALKPSTLLQVNMAKNRCSILDYDVVLMDTPGVDVTAQLDDCLDSYCMDADVFILVLNAESTVSRVERQFFKDVASKLSRPNLFILNNRWDKASSLEPEMEQKVKDQHMERCVNLLVDELGVYSTAQEAWERIYHVSALEALHIR---NGQITNPSGQTQQRYQEFLRFE 327

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q7YU24|MARF_DROME (Transmembrane GTPase Marf OS=Drosophila melanogaster OX=7227 GN=Marf PE=1 SV=1)

HSP 1 Score: 108.227 bits (269), Expect = 4.432e-23
Identity = 78/273 (28.57%), Postives = 135/273 (49.45%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRK-LEITKEDEIYDRIYFLSAREMSQIRIE----NNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN 1038
            K   I E + RD +K+  FG+ S GKS ++NAML +    S   HTT+ F  V+ S   ++Y +     ++           I++++  +   K   +  + +    +  +LL+  +  VD PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N+  E  +  K++  E C  FL K L+++ E E  +R++F+SARE  Q RIE    N   +       + R+ +F  FE   ++ I+
Sbjct:  125 KVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGEAYLMTEGSEEKLNVV------NIKQLANALCQEKLCESSLVRIFWPRERCSLLRDDVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEP-ECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECIS 390

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q811U4|MFN1_MOUSE (Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 SV=3)

HSP 1 Score: 100.138 bits (248), Expect = 1.498e-20
Identity = 95/382 (24.87%), Postives = 176/382 (46.07%), Query Frame = 1

Query:   61 LPETLKQLKNI---RKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIES------------KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREM-------SQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            + ET+  LK+    +K ++ I       +G++ E      +TE    V+ T  N   +LD I S            K  VI E ++R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+       +Q   E   +L +     + R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:    1 MAETVSPLKHFVLAKKAITAI-------FGQLLEF-----VTEGSHFVEATYRN--PELDRIASEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAE---GFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVN 359

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R4Z9|MFN1_RAT (Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 PE=1 SV=1)

HSP 1 Score: 99.3673 bits (246), Expect = 2.737e-20
Identity = 76/303 (25.08%), Postives = 146/303 (48.18%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNV----KKRFEDFMRFEYNLKKYIN--------DPQDNKTRRYMQEIKNIQDFLN 1104
            K  VI E ++R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ D +Y +     ++        +     +  ++K     A   + V        LL+  + +VD PG+   +++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + +  + E C  FL  +L++    E  +RI+F+SA+E+   R+     + +    +    + R ++F  FE   ++ I+        +    + ++ +  +KNI D +N
Sbjct:   63 KLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDKAYLMTEGSDEKKSVKTVNQLAHALHMDKDLK-----AGCLVHVFWPKAKCALLRDDLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHM-ERCLHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVN 359

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BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Match: sp|Q8R500|MFN2_RAT (Mitofusin-2 OS=Rattus norvegicus OX=10116 GN=Mfn2 PE=1 SV=1)

HSP 1 Score: 97.4413 bits (241), Expect = 1.029e-19
Identity = 70/273 (25.64%), Postives = 130/273 (47.62%), Query Frame = 1

Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLR-KLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            SK   I+E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V  +  D +               K + ++       +  +  A   + V        LLK G+ ++D PG    +++   I K   +AD+F+ V N    L   ++ FF    +  ++P++FI+ N+WD S ++ E   ++ +  + E C+ FL  +L +    +  DRI+F+SA+E+   R++    + +    + + F+    +F  FE   ++ I+
Sbjct:   83 SKVRGISEVLARRHMKVAFFGRTSNGKSTVINAMLWDKVLPSGIGHTTNCFLRVGGT--DGHEAFLLTEGSEEKKSVKTVNQLAHALH--QDEQLHAGSLVSVMWPNSKCPLLKDGLVLMDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKQFFHKVSERLSRPNIFILNNRWDASASEPEYMEEVRRQHM-ERCTSFLVDELGVVDRAQAGDRIFFVSAKEVLSARVQKAQGMPEGGGALAEGFQVRMFEFQNFERRFEECIS 350

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BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A5E4MV73 (Dynamin superfamily,Fzo/mitofusin HR2 domain,P-loop containing nucleoside triphosphate hydrolase,Dynamin OS=Cinara cedri OX=506608 GN=CINCED_3A012836 PE=3 SV=1)

HSP 1 Score: 119.783 bits (299), Expect = 2.490e-24
Identity = 87/308 (28.25%), Postives = 147/308 (47.73%), Query Frame = 1

Query:  238 ESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLN-------YALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKK----RFEDFMRFEYNLK----------KYINDPQDNKTRRYMQEIKNIQ 1092
            ESK   I E + RD +K+  FG+ S GKS ++NAMLGD    +   HTT+ F+ V+ S+  D+Y +     ++         E I  ++  +   K     E + V    D   LL+  + +VD PG      + D I  +  +AD+F+ V N       Y +  + + F K     S KP++FI+ N+WD S N+ E   Q+ K  ++      +++L++   DE   RI+F+SA+E+ Q R++    L  +   + +    R+ +F  FE+  +          K++N  Q  K     QE KN++
Sbjct:   56 ESKVRGICEVLTRDHMKVAFFGRTSNGKSTVVNAMLGDKVLPTGIGHTTNCFLQVEGSQSGDAYLVIEGSNEKQNV------ESISHLAHALNHEKQLNEKELVHVYWPKDRCVLLRDDVALVDSPGVDVTPHLDDWIDNHCIDADVFVLVANAESXLYVYQINGEKKFFHKVSSKLS-KPNIFILNNRWDASANEPEFLDQVRKQHMERATDFLMKELKVCTADEASTRIFFISAKEVLQARVQERKGLALNSGALAEGFSTRYMEFKEFEHRFEECISKSAIKTKFLNHSQQGKHLIKSQEQKNLK 356

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BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1A9X2I7 (Dynamin-type G domain-containing protein OS=Glossina brevipalpis OX=37001 PE=3 SV=1)

HSP 1 Score: 118.242 bits (295), Expect = 1.058e-23
Identity = 83/273 (30.40%), Postives = 143/273 (52.38%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRK-LEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFE----DFMRFEYNLKKYIN 1038
            K   I E + RD +K+  FG+ S GKS ++NAML +    +   HTT+ F  V+  +  ++Y IK    ++         ++I++++  +   K + N  I +    D  +LL+ G+  +D PG    + + D I  +   AD+F+ VLN    +T  ++ FF       +KP++FI+ N+WD S N ++E  +  K++  E C  FL K L+IT E+E  +R++F+SARE+ Q RIE       S   + + F+    +F  FE   ++ I+
Sbjct:  107 KVAGIREVLARDHMKVAFFGRTSNGKSSVINAMLREKILPNGIGHTTNCFCQVEGCDGSEAYLIKEGSDEKLNV------KDIKQLANALSQEKLSENSLIRIFWPRDRCSLLRDGVVFMDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHKVSQKLSKPNIFILNNRWDASAN-EQEFQESVKSQHTERCVDFLTKELKITNEEEAAERVFFVSAREVVQARIEKAKGNSPSSGAIAEGFQIRYFEFQDFERKFEECIS 372

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BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1W4V389 (transmembrane GTPase fzo isoform X2 OS=Drosophila ficusphila OX=30025 GN=LOC108091614 PE=3 SV=1)

HSP 1 Score: 114.775 bits (286), Expect = 1.028e-22
Identity = 80/264 (30.30%), Postives = 129/264 (48.86%), Query Frame = 1

Query:  235 IESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEI-TKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFE 1014
            +  K   I + + R  +K+  FG+ S GKS ++NAML +    SA  HTTS F  V+ + DD       + +    D +   E     S      +      I  S C    +LL   + ++D PG    +Q+ DC+ +   +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD + N + E  Q  K +  E C K L   L + + E++   RIY +SA E  Q+R   N    + +P  ++R+ +F RFE
Sbjct:   46 LADKISSIDKVLARKRMKVAFFGRTSNGKSAVINAMLHERILPSAMGHTTSCFCQVQANGDDEPEHVRIEEEEQQLDLSSLNELASAHSPRALKPRTLLYVNIPKSRC----SLLDYDVVLMDTPGVDVTAQLDDCLDRYCMDADVFILVLNAESTISRVERQFFKDVSSKLSRPNLFILNNRWDVASNQEPEMEQQVKDQHMERCLKLLIEDLRVYSDEEQAKKRIYHISALEALQLR---NGCKTNPNPQTQERYLEFQRFE 302

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BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A2H8TF58 (Transmembrane GTPase Marf OS=Melanaphis sacchari OX=742174 GN=Marf_0 PE=3 SV=1)

HSP 1 Score: 114.39 bits (285), Expect = 1.529e-22
Identity = 82/279 (29.39%), Postives = 142/279 (50.90%), Query Frame = 1

Query:  142 KICEINNKCD--ITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSL 960
            ++ ++N KC   I E E K   ++L++ SK+  I    EV+T    RD +K+  FG+ S GKS ++NAMLGD    S   HTT+ F+ V+ S+  D+Y +     ++         E +  ++  +   K     E + V    D  +LL+  + +VD PG      + D I  +  +AD+F+ V N    L   ++ FF       +KP++FI+ N+WD S N+ E   Q+ K  ++      +++L++   +E   RI+F+SA+E+ Q R++    L
Sbjct:   58 RMIDVNLKCPDVINESELK---SMLDYRSKVKGI---CEVLT----RDHMKVAFFGRTSNGKSTVVNAMLGDKVLPSGIGHTTNCFLQVEGSQTGDAYLVTEGSNEKQNV------ESVTHLAHALNYEKQLNEKELVHVYWPKDKCSLLRDDVALVDSPGVDVTPHLDDWIDAHCIDADVFVLVANAESTLMVTEKNFFHKVSTKLSKPNIFILNNRWDASANEPEFLDQVRKQHMERATDFLVKELKVCTPEEAVSRIFFISAKEVLQARVKERSGL 320

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BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Match: A0A1W4V2X5 (transmembrane GTPase fzo isoform X1 OS=Drosophila ficusphila OX=30025 GN=LOC108091614 PE=3 SV=1)

HSP 1 Score: 114.005 bits (284), Expect = 1.610e-22
Identity = 80/264 (30.30%), Postives = 129/264 (48.86%), Query Frame = 1

Query:  235 IESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEI-TKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFE 1014
            +  K   I + + R  +K+  FG+ S GKS ++NAML +    SA  HTTS F  V+ + DD       + +    D +   E     S      +      I  S C    +LL   + ++D PG    +Q+ DC+ +   +AD+FI VLN    ++  +R FFK      ++P++FI+ N+WD + N + E  Q  K +  E C K L   L + + E++   RIY +SA E  Q+R   N    + +P  ++R+ +F RFE
Sbjct:   74 LADKISSIDKVLARKRMKVAFFGRTSNGKSAVINAMLHERILPSAMGHTTSCFCQVQANGDDEPEHVRIEEEEQQLDLSSLNELASAHSPRALKPRTLLYVNIPKSRC----SLLDYDVVLMDTPGVDVTAQLDDCLDRYCMDADVFILVLNAESTISRVERQFFKDVSSKLSRPNLFILNNRWDVASNQEPEMEQQVKDQHMERCLKLLIEDLRVYSDEEQAKKRIYHISALEALQLR---NGCKTNPNPQTQERYLEFQRFE 330

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 99.7525 bits (247), Expect = 2.140e-21
Identity = 77/286 (26.92%), Postives = 144/286 (50.35%), Query Frame = 1

Query:  217 SSKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKS-EDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFED----FMRFEYNLKKYIN 1038
            S++L  IES   K  VI E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ + ED +Y       +          + + +++  +  +++  A   ++V        LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K    + C  FL  +L++   +E  + I+F+SA+E+   R++    + ++   + + F+D    F  FE   ++ I+
Sbjct:   52 STQLQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEEKSI------KTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHT-DRCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQSFERTFEECIS 330

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn1b (mitofusin-1 [Source:NCBI gene;Acc:103030239])

HSP 1 Score: 99.7525 bits (247), Expect = 2.327e-21
Identity = 77/286 (26.92%), Postives = 144/286 (50.35%), Query Frame = 1

Query:  217 SSKLDNIES---KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKS-EDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKAT-ANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFED----FMRFEYNLKKYIN 1038
            S++L  IES   K  VI E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ + ED +Y       +          + + +++  +  +++  A   ++V        LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S ++ E    + K    + C  FL  +L++   +E  + I+F+SA+E+   R++    + ++   + + F+D    F  FE   ++ I+
Sbjct:   52 STQLQEIESYTEKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDEDKAYLKTEGSEEEKSI------KTVNQLAHALHMDESLDAGCLVKVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMDDVRKQHT-DRCVNFLVEELKVVDREEAPNHIFFVSAKEVLNSRMQRAQGMPETGGALAEGFQDRLKEFQSFERTFEECIS 330

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: ENSAMXT00000043809.1 (mitofusin-1-like [Source:NCBI gene;Acc:103034819])

HSP 1 Score: 98.5969 bits (244), Expect = 5.816e-21
Identity = 76/302 (25.17%), Postives = 140/302 (46.36%), Query Frame = 1

Query:  244 KYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFED----FMRFEYNLKKYINDPQ-----DNKTRRYMQ---EIKNIQDFLN 1104
            K E I E + R  +K+  FG+ S GKS ++NAML +    S   HTT+ F+ V+ ++ D ++       +R        +     +  N+      +   + V        LL+  + ++D PG+   S++   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S+ + E    + K  +    S  + +L++   D+  +RI+F+SA+E    RI     + ++   +   F+D    F  FE   +++I+        +  T R  Q    +K I D +N
Sbjct:   64 KLEAIWEVLARRQMKVAFFGRTSNGKSTVINAMLRERVLPSGIGHTTNCFISVEGTDGDQAFLTTENSEERKSIKTVNQLAHALHMDRNLD-----SGCLVRVFWPKTKCALLRDDLVLMDSPGTDVTSELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVSERISKPNIFILNNRWDASETEPEYLDGVRKQHMDRCVSFLVDELKVVSPDQAPNRIFFVSAKEALSARIHRAQGMPETGAALADGFQDRLQEFQSFERTFEEFISHSSVKTKFEQHTIRAWQITESLKTIMDAIN 360

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Match: mfn2 (mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44])

HSP 1 Score: 94.3597 bits (233), Expect = 1.187e-19
Identity = 68/263 (25.86%), Postives = 134/263 (50.95%), Query Frame = 1

Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEY 1017
            SK   I E ++R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ +             +++ K ++ + +++  +  ++   A   + V        LL+  + +VD PG    +++   I K   +AD+F+ V N    L   ++ FF    +  + P++FI+ N+WD S ++ E   ++ +  + + CS FL  +L +    +  DRI+F+SA+E+ Q R++    + ++   + + F+  M FE+
Sbjct:   83 SKVAGIGEVLSRRHMKVVFFGRTSNGKSSVINAMLWDKVLPSGIGHTTNCFLRVEGTDGNE-----AFLLTEGSEERKNVKTVNQLAHALHQDEDLDAGSLVCVMWPKAKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMEEVRRQHM-DRCSSFLVDELGVVDRAQASDRIFFVSAKEVLQARVQKAQGMPEAGGALAEGFQARM-FEF 338

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Match: EDO42379 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S1L1])

HSP 1 Score: 93.5893 bits (231), Expect = 8.523e-20
Identity = 95/340 (27.94%), Postives = 159/340 (46.76%), Query Frame = 1

Query:   55 SILPETLKQLKNIRKTVSEIENN-DEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSED-DSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDND-DEESTQMSKTKIKEECSKFLRK-LEITKEDEIYDRIYFLSAREMSQIRIENNDSL--------VDSDPNVKKRFEDF-MRFEYNLKK 1029
            S L   +K  K I +TVSEI    DE N   IC     C+I E+    K  +  F+  +     +   ITE + RD +K+  FG+ S GKS ++NAML D        HTT+ F+ V  S+  D Y           +D+ + ++ + +I+  +   K   +  ++V        +L + + +VD PG      +   I K+  +AD+F+ V N    L   ++ FF       +KP++FI+ N+WD S  + D E  ++ K +  +    FL K L+   + +  DR++F+SA+E    R++ +  +        VD     K  FE+F  +FE  + K
Sbjct:   27 SPLHNFVKAKKKINETVSEIGKYLDEANR-FIC----GCEIAED---YKSNIKGFACDVAGFLGQVASITEVIARDQMKVAFFGRTSNGKSTVVNAMLQDRILPMGIGHTTNCFLSVNGSDSADPY------ILIPESDERRNVKTLGQIAHALFEEKLDHSSLVQVYWPKSRCKMLSEDVVLVDSPGIDVSPDLDLWIDKHCLDADVFVLVCNAESTLMVTEKNFFHKVNQKLSKPNIFILNNRWDASAGEPDVEMMELVKKQHLQRNVDFLSKELKCVDKKQAEDRVFFVSAKETLMSRMQKHQGMPEEGGAIHVDGFHGRKLEFENFEHKFEECISK 352

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 100.523 bits (249), Expect = 1.291e-21
Identity = 77/288 (26.74%), Postives = 141/288 (48.96%), Query Frame = 1

Query:  220 SKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICM-------DDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNV----KKRFEDFMRFEYNLKKYIN 1038
            S++     K  VI E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++DD SY                  EE    + N   +    +E+++   C+           LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S N+ E    + K    + C  FL  +L++   ++  +RI+F+SA+E+   R++    + ++   +    ++R ++F  FE   ++ I+
Sbjct:   67 SEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSD-----------EEKSIKTVNQMAHALHMDESLDAG-CLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHT-DRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPETGGALAEGFQERLKEFQSFERRFEECIS 341

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn1b (mitofusin 1 [Source:NCBI gene;Acc:101158009])

HSP 1 Score: 100.523 bits (249), Expect = 1.337e-21
Identity = 77/288 (26.74%), Postives = 141/288 (48.96%), Query Frame = 1

Query:  220 SKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDD-SYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICM-------DDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNV----KKRFEDFMRFEYNLKKYIN 1038
            S++     K  VI E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++DD SY                  EE    + N   +    +E+++   C+           LL+  + +VD PG+   +Q+   I K   +AD+F+ V N    L + ++ FF    +  +KP++FI+ N+WD S N+ E    + K    + C  FL  +L++   ++  +RI+F+SA+E+   R++    + ++   +    ++R ++F  FE   ++ I+
Sbjct:   67 SEIQAYADKLAVIKEVLARRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDDDRSYLKTEGSD-----------EEKSIKTVNQMAHALHMDESLDAG-CLVRVFWPKTKCALLRDDLVLVDSPGTDVTTQLDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASANEPEYMEDVRKQHT-DRCVNFLVEELKVVDREQAPNRIFFISAKEVLNSRMQRAQGMPETGGALAEGFQERLKEFQSFERRFEECIS 341

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BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: ENSORLT00000009003.2 (pep primary_assembly:ASM223467v1:17:11595384:11602171:-1 gene:ENSORLG00000007178.2 transcript:ENSORLT00000009003.2 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 91.2781 bits (225), Expect = 1.420e-19
Identity = 74/290 (25.52%), Postives = 142/290 (48.97%), Query Frame = 1

Query:  217 SSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSE-DDSYXXXXXXXXXXXXXXXXXXEEIERISG-NIKGNKATANETIEVSICM-------DDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVK----KRFEDFMRFE--YNLKKY 1032
            S ++ +  +K   I + + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++ D++Y                  EE   IS  N   +    + T++ S C+           LL+  + ++D PG+    ++   I K   +AD+F+ V N    L + +++FF    +  +KP++FI+ N+WD S  + +   ++ K  + + C  FL  +L +   +E   RI+F+SA+E+   R++    + ++   +     +R  +F RFE  + ++K+
Sbjct:   53 SLEMQSCATKLYTIRDVLLRRHMKVAFFGRTSNGKSTVINAMLRDRVLPSGIGHTTNCFLSVEGTDGDEAYLTSEAS------------EERRSISTVNQLAHALHMDPTLDSS-CLVKVFWPKSRCALLRNDLVLMDSPGTDVTLELDSWIDKFCLDADVFVLVGNAESTLMNTEKLFFHKVSERISKPNIFILHNRWDASVTEPDYIQEVRKQHL-DRCVGFLAEELGVVGPNEAPGRIFFISAKEVLSSRMQRAQGMPETGGALAEGFHERLTEFQRFERTFEVRKH 328

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Match: mfn2 (mitofusin 2 [Source:NCBI gene;Acc:101170481])

HSP 1 Score: 92.0485 bits (227), Expect = 6.201e-19
Identity = 69/264 (26.14%), Postives = 132/264 (50.00%), Query Frame = 1

Query:  241 SKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNK-ATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNY--ALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFL-RKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYN 1020
            SK   I E + R  +K+  FG+ S GKS ++NAML D    S   HTT+ F+ V+ ++               +++ K I+ + +++  +  ++   A   + V        LL+  + +VD PG    +++   I K   +AD+F+ V N    L   ++ FF    +  + P++FI+ N+WD S ++ E   ++ +  + + CS FL  +L +    +  DRI+F+SA+E+ Q R++    + ++   + + F+  M FE+ 
Sbjct:   83 SKVAGIGEVLARRHMKVVFFGRTSNGKSTVINAMLCDKVLPSGIGHTTNCFLRVEGTDGSE-----GFLLTEGSEEKKSIKTVNQLAHALHQDQDLDAGSLVCVMWPKVKCALLRDDLVLVDSPGIDVTTELDSWIDKFCLDADVFVLVANSESTLMQTEKSFFHKVNERLSSPNIFILNNRWDASASEPEYMDEVRRQHM-DRCSNFLVEELGVVDRAQASDRIFFVSAKEVLQARMQRVQGMPEAGGALAEGFQARM-FEFQ 339

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BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014753.1 (SMESG000014753.1)

HSP 1 Score: 1169.07 bits (3023), Expect = 0.000e+0
Identity = 598/606 (98.68%), Postives = 602/606 (99.34%), Query Frame = 1

Query:   46 MNISILPETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKWMKDMENFKATILSKNDDVQNSLLKRLEDIHNEIIHSPDLRSSEWVTSQLEHFTSEMKLKLQEAQLKQYKDFIHFIKTKDLINRKTYLSETKELNIKLMWNPIIVNPTDNVSKEACIVKEVMEKLAMIPIPNIPFQMFAQGVSLVGKLVIKRIEDSESEQHRQSIIQQLNSQRSNMSRIIEENVNEIKEYYMEKANEIIQLFQEKSKLFNEYWRRLEGILKDFDKDGFS 1863
            MNISILPETLKQLKNIRKTVSEIENND+INYGKI EINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFAS TAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKTKFIEEIERISG+IKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYF SAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKWMKDME+FKATILSKNDDVQNSLLKRLEDIHNEIIHSPDLRSSEWVTSQLEHFTSEMKLKLQEAQLKQYKDFIHFIK+KDLIN KTYLSETKELNIKLMWNPIIVNPTDNVSKEACIVKEVMEKLAMIPIPNIPFQMFAQGVSLVGKLVIKRIEDSESEQHRQSIIQQLNSQRSNMSRIIEENVNEIKEYYMEKANEIIQLFQEKSKLFNEYWRRLEGILKDFDKDGFS
Sbjct:    1 MNISILPETLKQLKNIRKTVSEIENNDKINYGKISEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKTKFIEEIERISGDIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFFSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKWMKDMEDFKATILSKNDDVQNSLLKRLEDIHNEIIHSPDLRSSEWVTSQLEHFTSEMKLKLQEAQLKQYKDFIHFIKSKDLINGKTYLSETKELNIKLMWNPIIVNPTDNVSKEACIVKEVMEKLAMIPIPNIPFQMFAQGVSLVGKLVIKRIEDSESEQHRQSIIQQLNSQRSNMSRIIEENVNEIKEYYMEKANEIIQLFQEKSKLFNEYWRRLEGILKDFDKDGFS 606

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BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014762.1 (SMESG000014762.1)

HSP 1 Score: 672.159 bits (1733), Expect = 0.000e+0
Identity = 370/623 (59.39%), Postives = 471/623 (75.60%), Query Frame = 1

Query:   46 MNISILPETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKWMKDMENFKATILSKNDDVQNSLLKRLEDIHNEIIHSPDLRSSEWVTSQLEHFTSEMKLKLQEAQLKQYKDFIHFIKTKDLINRKTYLSETKELNIKLMWNPIIVNPTD-----------NVSKEACIVKEVMEKLAMIPIPNIPFQMFAQGVS--LVGKLVIKR-----------IEDSESEQHRQSIIQQLNSQRSNMSRIIEENVNEIKEYYMEKANEIIQLFQEKSKLFNEYWRRLEGILKD 1842
            MN  IL ET  + +NIRK V EI+  DEINYGKI E+N KCDITEEEWKV + +LNFSSKLDNI+SK+EVI EKVNRD+VKIFLFGKVSVGKS LLN MLGDNYFAS TAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDK +FI+EIE +SG+IKGNKATANE IEVSI MDDE+LLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSK KI EECSKFL+ L++ K++EI +RIYFLS+ EM Q RIEN+DSL+ S    KKRF++F RFEYNLKKYI+ PQDNKTRRY +EIK +Q +L  E   F+ +IF EK  SLI KY K ++D+++FK  I  K +   N+++ ++E++ N+I+ SP++ ++EWVT++L H  +E+ +  +E + KQYK+F+ F+K ++ I +++  S+  +   K MW   IV P+D           N +K   ++ + +E L +  +  +P ++FA   S  ++  L +             ++  E EQ +Q+IIQQL+S+++  +  I++NV  I E+++EKANEI  +FQ K  +FNEYW ++E I ++
Sbjct:    1 MNTEILTETENRFENIRKIVKEIKRYDEINYGKISEMNKKCDITEEEWKVDQILLNFSSKLDNIKSKFEVINEKVNRDIVKIFLFGKVSVGKSTLLNTMLGDNYFASGTAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKKEFIKEIEIMSGDIKGNKATANENIEVSIRMDDESLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKEKINEECSKFLQDLDLMKKEEISERIYFLSSSEMFQFRIENDDSLIKSSKTAKKRFDEFTRFEYNLKKYISAPQDNKTRRYTEEIKKLQTYLCKECKDFKENIFKEKRYSLISKYRKLIEDLKDFKKEIKLKGERKNNNIIIKVENLLNDIMTSPNVTNTEWVTTELGHVHAELDIMFKEVKDKQYKEFVSFLKNQEGIGKESNFSKEGKPAFKSMWRTSIVKPSDKGLDVETADAVNPAKTGDVLNKTVEILPL--LGQLPTKIFALASSALIISGLAMTAASAVYASYANDMKVKEQEQQKQNIIQQLDSKKNIFNSNIKDNVEAITEHFIEKANEINGIFQRKIDMFNEYWSKIEEIFRE 621

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014755.1 (SMESG000014755.1)

HSP 1 Score: 207.994 bits (528), Expect = 1.277e-59
Identity = 127/373 (34.05%), Postives = 219/373 (58.71%), Query Frame = 1

Query:  202 TVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGN---KATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVD--SDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKWMKDMENFKATILSKNDDVQNSLLKRLEDIH-NEIIHSPDLRS 1302
            T+ NF  K + IE+K   I  KV +D +KI  FG VS GKSK+LN ++G+N F SA A TTS FV V+KS+   + ++ + ++  F   T    +++ ++ ++  N   +    +T++V + +++E ++K   EI DCPGS NK ++T+CI + S ++DIFIFV+   LT++++ FF+YQ   S+KPD+F+++N+WD+SD D    T+ S+ KIK E    L K      +E   RI+F+SA EM + RIE  +   +  +   ++ R+E+F+ FE +L +YI++P+ NK  R+ +E++     L +    F+ ++F  K+   +  Y     DM++    +    + +   LL+  ++IH N   +  DLR+
Sbjct:   47 TIENFVKKYEIIETKVRFIEGKVKKDSIKISFFGTVSAGKSKVLNTIIGENLFLSAVADTTSCFVAVRKSDRGRHYLRVEGSETNFDSLTNLKNKVKELTTHLSENTTGRLDTTKTVQVFLNIENE-IMKNNTEIFDCPGSNNKREVTECIMQQSLDSDIFIFVMTCTLTNEEKDFFEYQSKLSSKPDIFVLVNKWDKSDQDKTAVTEKSRIKIKREIVNLLTKDGNFSSEEASKRIFFVSALEMFKCRIERKEIFGNQRTRRAIEMRYEEFLSFEESLSRYIDNPEINKLERHDREVRETTRNLESIIESFKTELFKHKDLRELKTY-----DMKDLSGRLDKAYECILKDLLRETKEIHMNLSTNCHDLRT 413

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000014759.1 (SMESG000014759.1)

HSP 1 Score: 205.682 bits (522), Expect = 5.704e-58
Identity = 123/305 (40.33%), Postives = 188/305 (61.64%), Query Frame = 1

Query:  184 EWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERI----SGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVD--SDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEI 1080
            E K+   + +F  K + IE+K   I  KV +D +KI  FGKVS GKS++LN +LG N F SA A TTS FV V KS+   + ++   ++  F       ++++ +    S NI     TA +T++V + + +E +LK   EIVDCPGS NK ++T+CIKK S ++DIFIFV+   LTD+++ FF+YQ   S+KPD+F+++N+WD SD D +E+T  S+ KIK+E    L K       E  +RI+F+SA EM + R+EN D  V+  +   +  R  +F  FE +L  YI++P+  KT+R+ +E+
Sbjct:   41 ESKILHLIEDFIKKFEIIETKIGFIEGKVKKDSIKISFFGKVSAGKSRVLNTILGGNIFVSAVADTTSCFVSVTKSDRRCHYLRVDGSEDNFGSLENLKDKVKELTTYLSKNINRRLDTA-KTVQVFLNIKNE-ILKNKTEIVDCPGSNNKGEVTECIKKQSLDSDIFIFVMTCTLTDEEKDFFEYQSKLSSKPDIFVLVNKWDNSDKDRQENTNKSRDKIKKEIINLLTKNGNFSSKEASERIFFVSALEMFKSRVENADVFVNKKNQEAIAMRNYEFTSFEKSLSNYIDNPEKKKTKRHFREV 343

[Close]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Match: SMESG000070111.1 (SMESG000070111.1)

HSP 1 Score: 198.364 bits (503), Expect = 4.991e-56
Identity = 130/381 (34.12%), Postives = 224/381 (58.79%), Query Frame = 1

Query:   40 KKMNISILPETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKVKKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAMLGDNYFASATAHTTSSFVHVKKSEDDSYXXXXXXXXXXXXXXXXXXEEIERISGNIKGNKATANETIEVSICM-DDETLLKKGIEIVDCPGSGNKSQITDCIKKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDNDDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIENNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQDFLNTEFMKFQADIFNEKNNSLIPKYEKW 1179
            KKM+ +I  +  ++++  +K ++E+EN   I + ++C+          EWKV+K +  F  +   +E++   I E++++  +KIF FG VS GK++L+NA+LG  +F S   HTT  FVH+ KS D  Y+I  K+ +  +  K K IEE+E+IS   K   + + E+++V I + DD  +LK  +E++D PG+G+  ++ +C++ +  +ADI I++L   ++++D  FF  + + +TKPD+FI++N+WD+SD D +     +   +  +C   + K    K  +I  RI F+SA E+   RI+N +    S+ N K R+ DF RFE  +++YI +PQ  KTRRY +EIK +   LN   ++    I N    S + +YE +
Sbjct:   13 KKMSQNIDSDARQEMRKAKKLLTELENY--IGFEELCK----------EWKVQKKIKKFKDRFVELENQLNDIQEEISKKNIKIFFFGSVSSGKTRLINAILGGEFFMSTMNHTTKCFVHIMKSPDAKYKIVHKNQEFIYESKNKIIEEVEKISTFNKETSSMSQESVKVFIPIGDDNKILKGNVELIDSPGTGDIEELIECVQNHLSDADICIYLLCNDVSEEDERFFNIRINRTTKPDIFILVNKWDQSDQDQDSRLCETYKNLVGKCFGLVGKFGGPKTKDIDKRIIFISAIEVFGYRIKNKEP---SNRNQKIRYADFERFEDQIEEYIQNPQQLKTRRYKREIKTLLKELNIIIVELSKQINNIDFESCVKRYEGY 378

The following BLAST results are available for this feature:

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
MFN1	8.071e-21	24.75	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	2.207e-20	24.75	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN1	2.207e-20	24.75	mitofusin 1 [Source:HGNC Symbol;Acc:HGNC:18262]	[more]
MFN2	5.125e-20	25.18	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]
MFN2	5.125e-20	25.18	mitofusin 2 [Source:HGNC Symbol;Acc:HGNC:16877]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 1


Match Name	E-value	Identity	Description
fzo-1	5.511e-17	25.87	Transmembrane GTPase fzo-1 [Source:UniProtKB/Swis...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 4


Match Name	E-value	Identity	Description
fzo	9.962e-26	26.62	gene:FBgn0011596 transcript:FBtr0084399	[more]
Marf	2.224e-24	28.62	gene:FBgn0029870 transcript:FBtr0343373	[more]
Marf	4.421e-24	28.57	gene:FBgn0029870 transcript:FBtr0070910	[more]
Marf	4.421e-24	28.57	gene:FBgn0029870 transcript:FBtr0070909	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mfn1b	5.405e-21	25.66	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	5.405e-21	25.66	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	5.909e-21	25.53	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn1b	1.670e-20	26.28	mitofusin 1b [Source:ZFIN;Acc:ZDB-GENE-040426-1553...	[more]
mfn2	4.826e-20	26.24	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5


Match Name	E-value	Identity	Description
mfn1	5.428e-20	26.47	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	6.253e-20	26.47	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	6.253e-20	26.47	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	6.931e-20	26.47	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]
mfn1	6.994e-20	26.47	mitofusin 1 [Source:NCBI gene;Acc:548943]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5


Match Name	E-value	Identity	Description
Mfn1	2.141e-21	24.87	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]
Mfn1	2.141e-21	24.87	mitofusin 1 [Source:MGI Symbol;Acc:MGI:1914664]	[more]
Mfn2	1.826e-19	25.27	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.826e-19	25.27	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]
Mfn2	1.826e-19	25.27	mitofusin 2 [Source:MGI Symbol;Acc:MGI:2442230]	[more]

BLAST of Dynamin-type G domain-containing protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|O18412\|FZO_DROME	9.986e-25	26.62	Transmembrane GTPase fzo OS=Drosophila melanogaste...	[more]
sp\|Q7YU24\|MARF_DROME	4.432e-23	28.57	Transmembrane GTPase Marf OS=Drosophila melanogast...	[more]
sp\|Q811U4\|MFN1_MOUSE	1.498e-20	24.87	Mitofusin-1 OS=Mus musculus OX=10090 GN=Mfn1 PE=1 ...	[more]
sp\|Q8R4Z9\|MFN1_RAT	2.737e-20	25.08	Mitofusin-1 OS=Rattus norvegicus OX=10116 GN=Mfn1 ...	[more]
sp\|Q8R500\|MFN2_RAT	1.029e-19	25.64	Mitofusin-2 OS=Rattus norvegicus OX=10116 GN=Mfn2 ...	[more]

BLAST of Dynamin-type G domain-containing protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A0A5E4MV73	2.490e-24	28.25	Dynamin superfamily,Fzo/mitofusin HR2 domain,P-loo...	[more]
A0A1A9X2I7	1.058e-23	30.40	Dynamin-type G domain-containing protein OS=Glossi...	[more]
A0A1W4V389	1.028e-22	30.30	transmembrane GTPase fzo isoform X2 OS=Drosophila ...	[more]
A0A2H8TF58	1.529e-22	29.39	Transmembrane GTPase Marf OS=Melanaphis sacchari O...	[more]
A0A1W4V2X5	1.610e-22	30.30	transmembrane GTPase fzo isoform X1 OS=Drosophila ...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mfn1b	2.140e-21	26.92	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
mfn1b	2.327e-21	26.92	mitofusin-1 [Source:NCBI gene;Acc:103030239]	[more]
ENSAMXT00000043809.1	5.816e-21	25.17	mitofusin-1-like [Source:NCBI gene;Acc:103034819]	[more]
mfn2	1.187e-19	25.86	mitofusin 2 [Source:ZFIN;Acc:ZDB-GENE-081105-44]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 1


Match Name	E-value	Identity	Description
EDO42379	8.523e-20	27.94	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of Dynamin-type G domain-containing protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 4


Match Name	E-value	Identity	Description
mfn1b	1.291e-21	26.74	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
mfn1b	1.337e-21	26.74	mitofusin 1 [Source:NCBI gene;Acc:101158009]	[more]
ENSORLT00000009003.2	1.420e-19	25.52	pep primary_assembly:ASM223467v1:17:11595384:11602...	[more]
mfn2	6.201e-19	26.14	mitofusin 2 [Source:NCBI gene;Acc:101170481]	[more]

BLAST of Dynamin-type G domain-containing protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 5


Match Name	E-value	Identity	Description
SMESG000014753.1	0.000e+0	98.68	SMESG000014753.1	[more]
SMESG000014762.1	0.000e+0	59.39	SMESG000014762.1	[more]
SMESG000014755.1	1.277e-59	34.05	SMESG000014755.1	[more]
SMESG000014759.1	5.704e-58	40.33	SMESG000014759.1	[more]
SMESG000070111.1	4.991e-56	34.12	SMESG000070111.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034752 ID=SMED30034752|Name=Dynamin-type G domain-containing protein|organism=Schmidtea mediterranea sexual|type=transcript|length=1968bp
ATTTATTGTTAGAATTTTTATATCCGCATTTCAGATTTGAAAAAAATGAA
TATTTCAATTTTACCCGAAACATTAAAGCAATTGAAGAATATAAGAAAAA
CTGTCAGCGAAATAGAAAATAACGATGAAATTAATTATGGAAAAATATGC
GAAATAAATAACAAATGTGATATAACAGAAGAAGAGTGGAAAGTAAAAAA
GACCGTATTAAATTTCTCAAGCAAATTAGACAACATCGAAAGTAAATACG
AAGTCATCACCGAAAAAGTCAACAGAGATGTTGTCAAAATATTTCTTTTT
GGAAAAGTTTCAGTTGGCAAAAGCAAACTCCTGAATGCGATGTTGGGCGA
CAATTACTTTGCCTCGGCCACGGCTCACACAACGAGCAGTTTTGTCCATG
TCAAGAAATCGGAGGACGACAGCTACAGGATCAAAACTAAGGATACTGAT
CGAACGTTCACTGACAAAACAAAGTTCATTGAAGAAATTGAACGCATTTC
CGGAAACATAAAAGGTAATAAAGCCACGGCTAATGAAACCATTGAAGTGT
CGATATGCATGGATGACGAGACTCTATTGAAAAAAGGCATAGAAATTGTC
GACTGCCCCGGATCCGGAAACAAATCTCAAATTACAGACTGCATTAAGAA
AAATTCTCAAGAAGCGGATATATTCATATTTGTGTTGAATTACGCATTGA
CGGACGATGATAGGGTATTCTTCAAATATCAAGAGGATTCTTCAACTAAA
CCGGACGTTTTCATTGTTATAAATCAGTGGGACGAGTCTGATAATGATGA
TGAGGAGTCAACTCAAATGAGTAAAACTAAAATAAAAGAAGAATGTTCCA
AATTCCTGAGGAAATTAGAAATTACGAAGGAAGACGAAATTTATGACCGA
ATTTATTTTTTGTCAGCCCGTGAAATGTCTCAAATTCGAATTGAAAATAA
TGACAGTTTAGTCGACTCTGATCCTAATGTTAAAAAGCGATTCGAAGACT
TCATGCGGTTTGAATACAACCTAAAAAAATATATCAACGATCCTCAAGAC
AATAAAACCCGACGATATATGCAAGAGATCAAAAACATACAGGATTTCTT
GAACACAGAATTTATGAAATTTCAAGCTGATATTTTTAATGAAAAAAATA
ATTCCTTAATCCCAAAATATGAAAAATGGATGAAGGACATGGAGAACTTC
AAAGCGACAATACTGTCCAAAAATGACGATGTTCAGAATTCTTTGTTAAA
AAGATTGGAAGACATTCATAATGAAATTATCCACAGTCCAGATCTGAGGA
GCTCAGAATGGGTCACAAGTCAACTGGAACATTTCACCTCGGAAATGAAA
CTTAAGCTGCAAGAGGCTCAATTAAAACAATATAAAGATTTTATTCACTT
CATAAAAACAAAAGACCTAATAAATCGAAAAACTTATTTATCTGAGACAA
AAGAACTGAATATTAAGCTCATGTGGAATCCAATAATAGTCAATCCGACG
GATAATGTGTCCAAGGAGGCATGCATTGTGAAGGAAGTGATGGAGAAATT
GGCAATGATTCCTATTCCAAATATACCGTTTCAAATGTTTGCACAAGGAG
TGTCTCTTGTAGGGAAACTGGTCATAAAACGTATTGAAGATTCGGAGTCG
GAACAACATAGACAAAGCATTATACAACAATTGAATTCTCAACGGAGCAA
TATGTCCCGGATTATAGAAGAAAACGTGAATGAAATAAAGGAATATTATA
TGGAAAAGGCAAATGAAATAATTCAATTATTTCAAGAGAAAAGTAAATTG
TTCAACGAGTATTGGCGAAGGCTTGAAGGAATTTTGAAAGACTTTGATAA
GGATGGATTTAGTTAAAGTTTATTTAATGAATAATTGATATAAATAATAA
ATAATATTTACAATTTATTTATAATTAGCATGGATGTTGTAATCGTTTCA
CTTTTAGTTTGAATATTT

protein sequence of SMED30034752-orf-1

>SMED30034752-orf-1 ID=SMED30034752-orf-1|Name=SMED30034752-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=607bp
MNISILPETLKQLKNIRKTVSEIENNDEINYGKICEINNKCDITEEEWKV
KKTVLNFSSKLDNIESKYEVITEKVNRDVVKIFLFGKVSVGKSKLLNAML
GDNYFASATAHTTSSFVHVKKSEDDSYRIKTKDTDRTFTDKTKFIEEIER
ISGNIKGNKATANETIEVSICMDDETLLKKGIEIVDCPGSGNKSQITDCI
KKNSQEADIFIFVLNYALTDDDRVFFKYQEDSSTKPDVFIVINQWDESDN
DDEESTQMSKTKIKEECSKFLRKLEITKEDEIYDRIYFLSAREMSQIRIE
NNDSLVDSDPNVKKRFEDFMRFEYNLKKYINDPQDNKTRRYMQEIKNIQD
FLNTEFMKFQADIFNEKNNSLIPKYEKWMKDMENFKATILSKNDDVQNSL
LKRLEDIHNEIIHSPDLRSSEWVTSQLEHFTSEMKLKLQEAQLKQYKDFI
HFIKTKDLINRKTYLSETKELNIKLMWNPIIVNPTDNVSKEACIVKEVME
KLAMIPIPNIPFQMFAQGVSLVGKLVIKRIEDSESEQHRQSIIQQLNSQR
SNMSRIIEENVNEIKEYYMEKANEIIQLFQEKSKLFNEYWRRLEGILKDF
DKDGFS*

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **biological process**
Term	Definition
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0006697	ecdysone biosynthetic process
GO:0007005	mitochondrion organization
GO:0007029	endoplasmic reticulum organization
GO:0008053	mitochondrial fusion
GO:0008344	adult locomotory behavior
GO:0010636	positive regulation of mitochondrial fusion
GO:0019896	axonal transport of mitochondrion
GO:0034389	lipid particle organization
GO:0034976	response to endoplasmic reticulum stress
GO:0070584	mitochondrion morphogenesis
GO:0090140	regulation of mitochondrial fission

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000026	gut
PLANA:0000034	epidermis
PLANA:0000099	neuron
PLANA:0002028	dorsal-ventral muscle cell
PLANA:0002032	epidermal cell
PLANA:0003116	parenchymal cell
PLANA:0003117	parapharyngeal cell

Vocabulary: **INTERPRO**
Term	Definition
IPR027094	Mitofusin_fam
IPR027417	P-loop_NTPase
IPR022812	Dynamin_SF

Vocabulary: **molecular function**
Term	Definition
GO:0000166	nucleotide binding
GO:0003924	GTPase activity
GO:0005525	GTP binding
GO:0016787	hydrolase activity

Vocabulary: **cellular component**
Term	Definition
GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0005741	mitochondrial outer membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0031306	intrinsic component of mitochondrial outer membrane
GO:1904115	axon cytoplasm

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 6..26
None	No IPR available	GENE3D	G3DSA:3.40.50.300		coord: 82..328 e-value: 7.8E-23 score: 83.2
IPR022812	Dynamin superfamily	PFAM	PF00350	Dynamin_N	coord: 82..243 e-value: 1.3E-18 score: 67.6
IPR027094	Mitofusin family	PANTHER	PTHR10465	TRANSMEMBRANE GTPASE FZO1	coord: 5..406
IPR027417	P-loop containing nucleoside triphosphate hydrolase	SUPERFAMILY	SSF52540	P-loop containing nucleoside triphosphate hydrolases	coord: 64..293

Main menu

Dynamin-type G domain-containing protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 20

Owlery

blazegraph-runner