nanos-like protein

Overview


Name	nanos-like protein (ABO52809.1)
Smed ID	SMED30034750
Length (bp)	791

Neoblast Clusters

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.

Expression of nanos-like protein (SMED30034750) t-SNE clustered cells

Violin plots show distribution of expression levels for nanos-like protein (SMED30034750) in cells (dots) of each of the 12 neoblast clusters.

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of nanos-like protein (SMED30034750) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for nanos-like protein (SMED30034750) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

Anatomical Expression

PAGE et. al., 2020

SMED30034750

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 28

Expressed In	Reference Transcript	Gene Models	Published Transcript	Transcriptome	Publication	Lifecycle
testis	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:279364
prepharyngeal region	SMED30034750	h1SMcG0003273	SmedASXL_070230	SmedAsxl_ww_GCZZ01	PMID:27034770 Currie et al., 2016
X1 cell	SMED30034750	h1SMcG0003273	SmedASXL_070230	SmedAsxl_ww_GCZZ01	PMID:26114597 Zhu et al., 2015
X1 cell	SMED30034750	h1SMcG0003273	isotig19923	be_Smed_v2	PMID:22543868 Onal et al., 2012
X1 cell	SMED30034750	h1SMcG0003273	CUFF.280331.2	be_Smed_v2	PMID:22543868 Onal et al., 2012
ovary	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17376870 Wang et al., 2007	juvenile stage
ovary	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17376870 Wang et al., 2007
testis	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17376870 Wang et al., 2007
testis primordium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17376870 Wang et al., 2007	juvenile stage
testis primordium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17376870 Wang et al., 2007
gonad primoridium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17376870 Wang et al., 2007	juvenile stage
ovary	SMED30034750	h1SMcG0003273	EF153633	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
testis	SMED30034750	h1SMcG0003273	EF153633	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
spermatogonium	SMED30034750	h1SMcG0003273	EF153633	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
testis primordium	SMED30034750	h1SMcG0003273	EF153633	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007	juvenile stage
testis primordium	SMED30034750	h1SMcG0003273	EF153633	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
oogonial cell	SMED30034750	h1SMcG0003273	EF153633	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
ovary	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
testis	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
spermatogonium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
testis primordium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007	juvenile stage
testis primordium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
oogonial cell	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007
eye primordium	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:17390146 Handberg-Thorsager et al., 2007	juvenile stage
testis	SMED30034750	h1SMcG0003273	EF035555.1	smed_ncbi_20240424	PMID:20844018 Wang et al., 2010
early male germ cell	SMED30034750	h1SMcG0003273	Smed_nanos	GPL10652	PMID:20844018 Wang et al., 2010
neoblast	SMED30034750	h1SMcG0003273	SMED_04665_V2_1	GPL14150	PMID:22385657 Wagner et al., 2012
neoblast	SMED30034750	h1SMcG0003273	SMED_04665_V2_1	GPL14150_gene_models	PMID:22385657 Wagner et al., 2012

Note: Hover over icons to view figure legend

Homology

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BLAST of nanos-like protein vs. Ensembl Human
Match: NANOS1 (nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:23044])

HSP 1 Score: 88.9669 bits (219), Expect = 2.787e-22
Identity = 35/58 (60.34%), Postives = 46/58 (79.31%), Query Frame = 2

Query:  452 IELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            +++CVFCRNN E   +Y +H +K  +G+V CPVLR YTCPLC ++GD AHTIKYCP+S
Sbjct:    3 LQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLS 60

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BLAST of nanos-like protein vs. Ensembl Human
Match: NANOS1 (nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:23044])

HSP 1 Score: 90.5077 bits (223), Expect = 9.679e-21
Identity = 35/61 (57.38%), Postives = 47/61 (77.05%), Query Frame = 2

Query:  443 ESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            +  +++CVFCRNN E   +Y +H +K  +G+V CPVLR YTCPLC ++GD AHTIKYCP+S
Sbjct:  208 KPELQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLS 268

[Close]

BLAST of nanos-like protein vs. Ensembl Human
Match: NANOS2 (nanos C2HC-type zinc finger 2 [Source:NCBI gene;Acc:339345])

HSP 1 Score: 77.7962 bits (190), Expect = 2.343e-17
Identity = 30/58 (51.72%), Postives = 43/58 (74.14%), Query Frame = 2

Query:  458 LCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMN 631
            LC FC++N E   +Y SH++K  +G V CP+LR+Y CP+C +TGD AHT+KYCP++  
Sbjct:   62 LCNFCKHNGESRHVYSSHQLKTPDGVVVCPILRHYVCPVCGATGDQAHTLKYCPLNGG 119

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BLAST of nanos-like protein vs. Ensembl Human
Match: NANOS3 (nanos C2HC-type zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:22048])

HSP 1 Score: 72.7886 bits (177), Expect = 3.580e-15
Identity = 33/79 (41.77%), Postives = 46/79 (58.23%), Query Frame = 2

Query:  458 LCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIK 694
            LC FC++N E   +Y SH +KD  G+V CP+LR+Y CP C +T + AHT ++CP+    T Q   +     TRN    K
Sbjct:   57 LCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATRERAHTRRFCPL----TGQGYTSVYSHTTRNSAGKK 131

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Query:  458 LCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIK 694
            LC FC++N E   +Y SH +KD  G+V CP+LR+Y CP C +T + AHT ++CP+    T Q   +     TRN    K
Sbjct:   57 LCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATRERAHTRRFCPL----TGQGYTSVYSHTTRNSAGKK 131

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BLAST of nanos-like protein vs. Ensembl Fly
Match: nos (gene:FBgn0002962 transcript:FBtr0083732)

HSP 1 Score: 78.9518 bits (193), Expect = 1.541e-16
Identity = 32/53 (60.38%), Postives = 38/53 (71.70%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCP 619
            CVFC NNNEP  +  SH V+D   +V CP LR Y CP+C ++GD AHTIKYCP
Sbjct:  319 CVFCENNNEPEAVINSHSVRDNFNRVLCPKLRTYVCPICGASGDSAHTIKYCP 371

[Close]

BLAST of nanos-like protein vs. Ensembl Fly
Match: nos (gene:FBgn0002962 transcript:FBtr0335019)

HSP 1 Score: 78.9518 bits (193), Expect = 1.671e-16
Identity = 32/53 (60.38%), Postives = 38/53 (71.70%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCP 619
            CVFC NNNEP  +  SH V+D   +V CP LR Y CP+C ++GD AHTIKYCP
Sbjct:  300 CVFCENNNEPEAVINSHSVRDNFNRVLCPKLRTYVCPICGASGDSAHTIKYCP 352

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BLAST of nanos-like protein vs. Ensembl Zebrafish
Match: nanos1 (nanos homolog 1 [Source:NCBI gene;Acc:322903])

HSP 1 Score: 91.2781 bits (225), Expect = 1.039e-21
Identity = 38/69 (55.07%), Postives = 50/69 (72.46%), Query Frame = 2

Query:  437 RKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQ 643
            R +   ++CVFCRNN  P E+Y SH +K  +G+V CP+LR YTCPLC++ GD AHTIKYCP+S +   Q
Sbjct:  143 RNKQEPKICVFCRNNGAPEEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKDQPAQ 211

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BLAST of nanos-like protein vs. Ensembl Zebrafish
Match: nanos2 (nanos homolog 2 [Source:ZFIN;Acc:ZDB-GENE-130321-1])

HSP 1 Score: 78.9518 bits (193), Expect = 6.285e-18
Identity = 34/63 (53.97%), Postives = 45/63 (71.43%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVS 649
            C FCR N E  ++Y SH++K  +G+V CP+LR+Y CPLC++TGD AHT  YCP   N TK+ S
Sbjct:   83 CGFCRQNGETAQIYRSHRLKARDGRVLCPILRSYVCPLCSATGDRAHTRYYCP-RRNITKKNS 144

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BLAST of nanos-like protein vs. Ensembl Zebrafish
Match: nanos3 (nanos homolog 3 [Source:ZFIN;Acc:ZDB-GENE-011221-1])

HSP 1 Score: 70.8626 bits (172), Expect = 9.232e-15
Identity = 27/56 (48.21%), Postives = 38/56 (67.86%), Query Frame = 2

Query:  455 ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPI 622
            + C FC++N E   +Y SH +K+ +G V CP LR Y CPLC +TG  AHT ++CP+
Sbjct:   90 KFCSFCKHNGETEAVYTSHYLKNRDGDVMCPYLRQYKCPLCGATGAKAHTKRFCPM 145

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BLAST of nanos-like protein vs. Ensembl Xenopus
Match: dag1 (dystroglycan 1 [Source:Xenbase;Acc:XB-GENE-1015769])

HSP 1 Score: 80.4925 bits (197), Expect = 1.386e-18
Identity = 30/54 (55.56%), Postives = 42/54 (77.78%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPI 622
            C FCR+N E   +Y SH+++  +G+V CPVLR YTCPLC + GD+AHT++YCP+
Sbjct:   61 CGFCRSNREAQSLYSSHRLRAPDGRVLCPVLRGYTCPLCGANGDWAHTMRYCPL 114

[Close]

BLAST of nanos-like protein vs. Ensembl Xenopus
Match: NANOS3 (nanos C2HC-type zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:22048])

HSP 1 Score: 77.7962 bits (190), Expect = 3.000e-17
Identity = 37/98 (37.76%), Postives = 52/98 (53.06%), Query Frame = 2

Query:  437 RKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 730
            R E  +  C FC++N E   +Y  H +KD  G+V CP+LRNY C  C +TGD AHT ++CP++      V   +L    RN I +   S+    L I 
Sbjct:   38 RGEESVAGCTFCKHNGESKHIYSKHSLKDKQGRVVCPILRNYVCSQCGATGDTAHTRRFCPLTQKDYCSVYQGTL----RNSIPVSLISLEPQFLYIV 131

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BLAST of nanos-like protein vs. Ensembl Xenopus
Match: ENSXETT00000051581.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:14929187:14937418:1 gene:ENSXETG00000018509.1 transcript:ENSXETT00000051581.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 8.804e-15
Identity = 28/56 (50.00%), Postives = 39/56 (69.64%), Query Frame = 2

Query:  455 ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPI 622
            + C FC++N E   +Y +H +++ NG + CPVLR YTCPLC +TG  +HT KYCP 
Sbjct:  196 KFCKFCKHNGESSRVYSTHTLRNSNGIIICPVLRKYTCPLCGATGALSHTRKYCPF 251

[Close]

BLAST of nanos-like protein vs. Ensembl Xenopus
Match: ENSXETT00000051579.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:1:14928537:14937418:1 gene:ENSXETG00000018509.1 transcript:ENSXETT00000051579.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 73.559 bits (179), Expect = 1.135e-14
Identity = 28/56 (50.00%), Postives = 39/56 (69.64%), Query Frame = 2

Query:  455 ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPI 622
            + C FC++N E   +Y +H +++ NG + CPVLR YTCPLC +TG  +HT KYCP 
Sbjct:  213 KFCKFCKHNGESSRVYSTHTLRNSNGIIICPVLRKYTCPLCGATGALSHTRKYCPF 268

[Close]

BLAST of nanos-like protein vs. Ensembl Mouse
Match: Nanos1 (nanos C2HC-type zinc finger 1 [Source:MGI Symbol;Acc:MGI:2669254])

HSP 1 Score: 91.2781 bits (225), Expect = 2.159e-21
Identity = 38/74 (51.35%), Postives = 51/74 (68.92%), Query Frame = 2

Query:  407 LHKLRTSNQIRK-ESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            LH    +   R  +  +++CVFCRNN E   +Y +H +K  +G+V CPVLR YTCPLC ++GD AHTIKYCP+S
Sbjct:  170 LHAASGATAARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLS 243

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BLAST of nanos-like protein vs. Ensembl Mouse
Match: Nanos2 (nanos C2HC-type zinc finger 2 [Source:MGI Symbol;Acc:MGI:2676627])

HSP 1 Score: 78.5666 bits (192), Expect = 7.712e-18
Identity = 32/62 (51.61%), Postives = 46/62 (74.19%), Query Frame = 2

Query:  458 LCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQ 643
            +C FC++N E   +Y SH++K   G V CP+LR+Y CPLC +TGD AHT+KYCP  +N+++Q
Sbjct:   60 ICNFCKHNGESRHVYTSHQLKTPEGVVVCPILRHYVCPLCGATGDQAHTLKYCP--LNSSQQ 119

[Close]

BLAST of nanos-like protein vs. Ensembl Mouse
Match: Nanos3 (nanos C2HC-type zinc finger 3 [Source:MGI Symbol;Acc:MGI:2675387])

HSP 1 Score: 73.559 bits (179), Expect = 1.332e-15
Identity = 33/77 (42.86%), Postives = 46/77 (59.74%), Query Frame = 2

Query:  425 SNQIRKESHI---ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQV 646
            S Q  KES      LC FC++N E   +Y SH +KD  G+V CP+LR+Y CP C +T + AHT ++CP++      V
Sbjct:   42 SQQASKESSAAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTSQGYTSV 118

[Close]

BLAST of nanos-like protein vs. Ensembl Mouse
Match: Nanos3 (nanos C2HC-type zinc finger 3 [Source:MGI Symbol;Acc:MGI:2675387])

HSP 1 Score: 73.559 bits (179), Expect = 1.389e-15
Identity = 33/77 (42.86%), Postives = 46/77 (59.74%), Query Frame = 2

Query:  425 SNQIRKESHI---ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQV 646
            S Q  KES      LC FC++N E   +Y SH +KD  G+V CP+LR+Y CP C +T + AHT ++CP++      V
Sbjct:   42 SQQASKESSAAPERLCSFCKHNGESRAIYQSHVLKDEAGRVLCPILRDYVCPQCGATQEHAHTRRFCPLTSQGYTSV 118

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BLAST of nanos-like protein vs. UniProt/SwissProt
Match: sp|E7FDB3|NANO1_DANRE (Nanos homolog 1 OS=Danio rerio OX=7955 GN=nanos1 PE=2 SV=1)

HSP 1 Score: 91.2781 bits (225), Expect = 7.843e-21
Identity = 38/69 (55.07%), Postives = 50/69 (72.46%), Query Frame = 2

Query:  437 RKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQ 643
            R +   ++CVFCRNN  P E+Y SH +K  +G+V CP+LR YTCPLC++ GD AHTIKYCP+S +   Q
Sbjct:  143 RNKQEPKICVFCRNNGAPEEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKDQPAQ 211

[Close]

BLAST of nanos-like protein vs. UniProt/SwissProt
Match: sp|Q80WY3|NANO1_MOUSE (Nanos homolog 1 OS=Mus musculus OX=10090 GN=Nanos1 PE=2 SV=2)

HSP 1 Score: 91.2781 bits (225), Expect = 1.510e-20
Identity = 38/74 (51.35%), Postives = 51/74 (68.92%), Query Frame = 2

Query:  407 LHKLRTSNQIRK-ESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            LH    +   R  +  +++CVFCRNN E   +Y +H +K  +G+V CPVLR YTCPLC ++GD AHTIKYCP+S
Sbjct:  170 LHAASGATAARLLKPELQVCVFCRNNKEAVALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLS 243

[Close]

BLAST of nanos-like protein vs. UniProt/SwissProt
Match: sp|Q8WY41|NANO1_HUMAN (Nanos homolog 1 OS=Homo sapiens OX=9606 GN=NANOS1 PE=1 SV=2)

HSP 1 Score: 90.5077 bits (223), Expect = 4.648e-20
Identity = 35/61 (57.38%), Postives = 47/61 (77.05%), Query Frame = 2

Query:  443 ESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            +  +++CVFCRNN E   +Y +H +K  +G+V CPVLR YTCPLC ++GD AHTIKYCP+S
Sbjct:  208 KPELQVCVFCRNNKEAMALYTTHILKGPDGRVLCPVLRRYTCPLCGASGDNAHTIKYCPLS 268

[Close]

BLAST of nanos-like protein vs. UniProt/SwissProt
Match: sp|Q07937|NANO1_XENLA (Nanos homolog 1 OS=Xenopus laevis OX=8355 GN=nanos1 PE=1 SV=1)

HSP 1 Score: 85.1149 bits (209), Expect = 1.348e-19
Identity = 31/54 (57.41%), Postives = 43/54 (79.63%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPI 622
            C FCR+N E   +Y SH+++ L+G+V CPVLR YTCPLC + GD+AHT++YCP+
Sbjct:   57 CGFCRSNREALSLYTSHRLRALDGRVLCPVLRGYTCPLCGANGDWAHTMRYCPL 110

[Close]

BLAST of nanos-like protein vs. UniProt/SwissProt
Match: sp|Q90ZZ5|NANO1_XENBO (Nanos homolog 1 OS=Xenopus borealis OX=8354 GN=nanos1 PE=2 SV=1)

HSP 1 Score: 84.3445 bits (207), Expect = 3.119e-19
Identity = 31/54 (57.41%), Postives = 43/54 (79.63%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPI 622
            C FCR+N E   +Y SH+++ L+G+V CPVLR YTCPLC + GD+AHT++YCP+
Sbjct:   61 CGFCRSNKEAMSLYSSHRLRSLDGRVLCPVLRGYTCPLCGANGDWAHTMRYCPL 114

[Close]

BLAST of nanos-like protein vs. TrEMBL
Match: A4UCR6 (Nanos-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 443.736 bits (1140), Expect = 2.015e-156
Identity = 232/233 (99.57%), Postives = 233/233 (100.00%), Query Frame = 2

Query:   32 MRTGESYFVLIHHTLKLNLMLNHPESLKMANTSPFIWQXXXXXXXXXXXXXXXXXYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 730
            MRTGESYFVLIHHTLKLNLMLN+PESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA
Sbjct:    1 MRTGESYFVLIHHTLKLNLMLNYPESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 233

[Close]

BLAST of nanos-like protein vs. TrEMBL
Match: A5Y5A4 (Nanos-like protein OS=Schmidtea mediterranea OX=79327 PE=2 SV=1)

HSP 1 Score: 404.831 bits (1039), Expect = 2.093e-141
Identity = 213/214 (99.53%), Postives = 214/214 (100.00%), Query Frame = 2

Query:   89 MLNHPESLKMANTSPFIWQXXXXXXXXXXXXXXXXXYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 730
            MLNHPESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACI+PNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA
Sbjct:    1 MLNHPESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACIIPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 214

[Close]

BLAST of nanos-like protein vs. TrEMBL
Match: F8WTH7 (Nanos-related protein OS=Dugesia ryukyuensis OX=79738 GN=nanos PE=2 SV=1)

HSP 1 Score: 288.886 bits (738), Expect = 4.024e-96
Identity = 144/177 (81.36%), Postives = 162/177 (91.53%), Query Frame = 2

Query:  116 MANTSPFIWQXXXXXXXXXXXXXXXXXYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQV 646
            M N +P +WQSVTSN +  +S+K+  N  RTNVACILPNLLQK ++KTDF+LL E+D+D++FRSD+KLSKELDRWVALLEAWPE+HITLDRS WLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS N++K +
Sbjct:    1 MTNMNPSLWQSVTSNVMCLNSSKTGSNMSRTNVACILPNLLQKTVSKTDFTLLAEDDHDNVFRSDVKLSKELDRWVALLEAWPERHITLDRSTWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISSNSSKGL 177

[Close]

BLAST of nanos-like protein vs. TrEMBL
Match: Q5H7Z0 (Nanos-related protein OS=Dugesia japonica OX=6161 GN=Djnos PE=2 SV=1)

HSP 1 Score: 288.5 bits (737), Expect = 7.187e-96
Identity = 144/177 (81.36%), Postives = 162/177 (91.53%), Query Frame = 2

Query:  116 MANTSPFIWQXXXXXXXXXXXXXXXXXYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQV 646
            M N +P +WQSVTSN +  +S+KS  N  RTNVACILPNLLQK ++KTDF+LL E+D+D++FRSD+KLSKELDRWVALLEAWPE+HITLDRS WLRLLHK+RTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS N++K +
Sbjct:    1 MTNMNPSLWQSVTSNIMCLNSSKSGSNMSRTNVACILPNLLQKTVSKTDFTLLAEDDHDNVFRSDVKLSKELDRWVALLEAWPERHITLDRSTWLRLLHKVRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISSNSSKSL 177

[Close]

BLAST of nanos-like protein vs. TrEMBL
Match: A0A068W982 (Nanos protein OS=Echinococcus granulosus OX=6210 GN=EgrG_000861500 PE=3 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 1.844e-28
Identity = 53/104 (50.96%), Postives = 76/104 (73.08%), Query Frame = 2

Query:  323 KELDRWVALLEAWPEKHITLDRSIWLRL---LHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            ++++RW  L++ + E+ I +D  +  RL   L +L    +   E++++LCVFCRNNNE FEMY SHKVKD  G+V CPVLR + CPLC++TGD+AHTI+YCP+S
Sbjct:   51 EQINRWRDLIKTYYEQGIPMDNPLLYRLTNFLGQLVPLIRHLSEANMDLCVFCRNNNETFEMYTSHKVKDRAGRVICPVLRRFVCPLCSATGDYAHTIRYCPLS 154

[Close]

BLAST of nanos-like protein vs. Ensembl Cavefish
Match: NANOS1 (nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;Acc:HGNC:23044])

HSP 1 Score: 92.0485 bits (227), Expect = 1.909e-22
Identity = 37/71 (52.11%), Postives = 51/71 (71.83%), Query Frame = 2

Query:  431 QIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQ 643
            ++ +++  ++CVFCRNN  P E+Y SH +K   G+V CP+LR YTCPLC++ GD AHTIKYCP+S     Q
Sbjct:   97 RLERDAEPKICVFCRNNGAPEEVYGSHVLKTPEGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKEQPAQ 167

[Close]

BLAST of nanos-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000053799.1 (pep primary_assembly:Astyanax_mexicanus-2.0:24:9379857:9381793:1 gene:ENSAMXG00000043091.1 transcript:ENSAMXT00000053799.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 89.3521 bits (220), Expect = 1.432e-21
Identity = 37/63 (58.73%), Postives = 46/63 (73.02%), Query Frame = 2

Query:  455 ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQ 643
            ++CVFCRNN  P E+Y SH +K   G+V CP+LR YTCPLC++ GD AHTIKYCP+S     Q
Sbjct:  104 KICVFCRNNGAPEEVYGSHVLKTPEGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKEQPAQ 166

[Close]

BLAST of nanos-like protein vs. Ensembl Cavefish
Match: nanos2 (nanos homolog 2 [Source:ZFIN;Acc:ZDB-GENE-130321-1])

HSP 1 Score: 79.7221 bits (195), Expect = 4.943e-18
Identity = 33/63 (52.38%), Postives = 43/63 (68.25%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVS 649
            C FCR N E  E+Y SH+++  +G+V CPVLR+Y CPLC +TGD AHT  YCP   +T  + S
Sbjct:   96 CAFCRRNGESTEVYRSHRLRRRDGRVMCPVLRSYMCPLCGATGDTAHTRLYCPNRSDTEPRRS 158

[Close]

BLAST of nanos-like protein vs. Ensembl Cavefish
Match: ENSAMXT00000056869.1 (nanos homolog 1 [Source:NCBI gene;Acc:103030775])

HSP 1 Score: 71.2478 bits (173), Expect = 6.354e-14
Identity = 29/62 (46.77%), Postives = 40/62 (64.52%), Query Frame = 2

Query:  461 CVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQV 646
            C FC++N E   +Y SH++KD +G V CP LR Y CP C +TG  AHT ++CP+  +T   V
Sbjct:  250 CSFCKHNGEAESVYTSHRLKDRSGCVICPYLRRYACPQCGATGASAHTRRFCPLVDSTYSSV 311

[Close]

BLAST of nanos-like protein vs. Ensembl Sea Lamprey
Match: ENSPMAT00000011356.1 (pep scaffold:Pmarinus_7.0:GL477149:1779:2000:1 gene:ENSPMAG00000010329.1 transcript:ENSPMAT00000011356.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 81.2629 bits (199), Expect = 1.988e-20
Identity = 34/56 (60.71%), Postives = 40/56 (71.43%), Query Frame = 2

Query:  458 LCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPIS 625
            +CVFCRNN E   +Y  H +K  +G+V CP LR YTCPLC   GD AHTIKYCP+S
Sbjct:    5 VCVFCRNNGEAEAVYAGHVLKAPDGRVLCPRLRAYTCPLCGVNGDRAHTIKYCPLS 60

[Close]

BLAST of nanos-like protein vs. Ensembl Nematostella
Match: NOS1 (Nanos 1; Predicted protein [Source:UniProtKB/TrEMBL;Acc:Q4PLU3])

HSP 1 Score: 88.9669 bits (219), Expect = 1.955e-21
Identity = 37/74 (50.00%), Postives = 51/74 (68.92%), Query Frame = 2

Query:  419 RTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTK 640
            R + + +K  +  +CVFCRNN E  ++Y SH +KD  G  TCP+LR YTCPLC ++G  +HTIKYCP + N +K
Sbjct:  138 RKNRENKKNRNANVCVFCRNNGESKKVYSSHVLKDAEGNTTCPILRAYTCPLCKASGSQSHTIKYCPKNKNGSK 211

[Close]

BLAST of nanos-like protein vs. Ensembl Nematostella
Match: EDO49152 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7RH35])

HSP 1 Score: 63.929 bits (154), Expect = 2.828e-12
Identity = 24/40 (60.00%), Postives = 31/40 (77.50%), Query Frame = 2

Query:  455 ELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPL 574
            ++CVFCRNN E  E+Y SH +K  +GK TCP+LR YTCP+
Sbjct:  154 QVCVFCRNNGESEEVYASHVLKSADGKTTCPILRAYTCPI 193

[Close]

BLAST of nanos-like protein vs. Ensembl Medaka
Match: nanos1a (nanos1 [Source:NCBI gene;Acc:100144352])

HSP 1 Score: 87.0409 bits (214), Expect = 1.260e-20
Identity = 36/65 (55.38%), Postives = 47/65 (72.31%), Query Frame = 2

Query:  437 RKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMN 631
            R +    +CVFCRNN  P E+Y +H +K   G+V CP+LR YTCPLC++ GD AHTIKYCP+S +
Sbjct:  104 RDKPEPRVCVFCRNNGAPEEVYGTHILKTGEGRVLCPILRAYTCPLCSANGDNAHTIKYCPLSRD 168

[Close]

BLAST of nanos-like protein vs. Ensembl Medaka
Match: nanos2 (nanos2 protein [Source:NCBI gene;Acc:100301601])

HSP 1 Score: 78.9518 bits (193), Expect = 7.588e-18
Identity = 32/58 (55.17%), Postives = 42/58 (72.41%), Query Frame = 2

Query:  446 SHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCP 619
            S  + C FC+ N E  ++Y SH ++  + KVTCP+LRNYTCP+C +TGD AHT KYCP
Sbjct:   81 SPADYCRFCKQNGETRQVYRSHALRSDDRKVTCPILRNYTCPICGATGDRAHTRKYCP 138

[Close]

BLAST of nanos-like protein vs. Ensembl Medaka
Match: nanos3 (nanos C2HC-type zinc finger 3 [Source:NCBI gene;Acc:100144282])

HSP 1 Score: 67.3958 bits (163), Expect = 2.714e-13
Identity = 28/54 (51.85%), Postives = 36/54 (66.67%), Query Frame = 2

Query:  458 LCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCP 619
            +C FCR+N E   +Y SH +K+  G V CP LR Y CPLC +TG  AHT ++CP
Sbjct:  133 VCSFCRHNGESEMVYRSHWLKNQKGDVLCPYLRQYVCPLCGATGAKAHTKRFCP 186

[Close]

BLAST of nanos-like protein vs. Planmine SMEST
Match: SMESG000018169.1 (SMESG000018169.1)

HSP 1 Score: 443.736 bits (1140), Expect = 5.603e-160
Identity = 232/233 (99.57%), Postives = 233/233 (100.00%), Query Frame = 2

Query:   32 MRTGESYFVLIHHTLKLNLMLNHPESLKMANTSPFIWQXXXXXXXXXXXXXXXXXYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 730
            MRTGESYFVLIHHTLKLNLMLN+PESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA
Sbjct:    1 MRTGESYFVLIHHTLKLNLMLNYPESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 233

[Close]

BLAST of nanos-like protein vs. Planmine SMEST
Match: SMESG000018169.1 (SMESG000018169.1)

HSP 1 Score: 427.557 bits (1098), Expect = 1.163e-153
Identity = 227/233 (97.42%), Postives = 228/233 (97.85%), Query Frame = 2

Query:   32 MRTGESYFVLIHHTLKLNLMLNHPESLKMANTSPFIWQXXXXXXXXXXXXXXXXXYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 730
            MRTGESYFVLIHHTLKLNLMLN+PESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACILPNLLQKNIAKTD     EEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA
Sbjct:    1 MRTGESYFVLIHHTLKLNLMLNYPESLKMANTSPFIWQSVTSNNVSYSSNKSNVNYPRTNVACILPNLLQKNIAKTD-----EEDNDSLFRSDLKLSKELDRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNNNEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMNTTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA 228

The following BLAST results are available for this feature:

BLAST of nanos-like protein vs. Ensembl Human
BLAST of nanos-like protein vs. Ensembl Celegans
BLAST of nanos-like protein vs. Ensembl Fly
BLAST of nanos-like protein vs. Ensembl Zebrafish
BLAST of nanos-like protein vs. Ensembl Xenopus
BLAST of nanos-like protein vs. Ensembl Mouse
BLAST of nanos-like protein vs. UniProt/SwissProt
BLAST of nanos-like protein vs. TrEMBL
BLAST of nanos-like protein vs. Ensembl Cavefish
BLAST of nanos-like protein vs. Ensembl Sea Lamprey
BLAST of nanos-like protein vs. Ensembl Yeast
BLAST of nanos-like protein vs. Ensembl Nematostella
BLAST of nanos-like protein vs. Ensembl Medaka
BLAST of nanos-like protein vs. Planmine SMEST

BLAST of nanos-like protein vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5


Match Name	E-value	Identity	Description
NANOS1	2.787e-22	60.34	nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;...	[more]
NANOS1	9.679e-21	57.38	nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;...	[more]
NANOS2	2.343e-17	51.72	nanos C2HC-type zinc finger 2 [Source:NCBI gene;Ac...	[more]
NANOS3	3.580e-15	41.77	nanos C2HC-type zinc finger 3 [Source:HGNC Symbol;...	[more]
NANOS3	3.580e-15	41.77	nanos C2HC-type zinc finger 3 [Source:HGNC Symbol;...	[more]

BLAST of nanos-like protein vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of nanos-like protein vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2


Match Name	E-value	Identity	Description
nos	1.541e-16	60.38	gene:FBgn0002962 transcript:FBtr0083732	[more]
nos	1.671e-16	60.38	gene:FBgn0002962 transcript:FBtr0335019	[more]

BLAST of nanos-like protein vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 3


Match Name	E-value	Identity	Description
nanos1	1.039e-21	55.07	nanos homolog 1 [Source:NCBI gene;Acc:322903]	[more]
nanos2	6.285e-18	53.97	nanos homolog 2 [Source:ZFIN;Acc:ZDB-GENE-130321-1...	[more]
nanos3	9.232e-15	48.21	nanos homolog 3 [Source:ZFIN;Acc:ZDB-GENE-011221-1...	[more]

BLAST of nanos-like protein vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 4


Match Name	E-value	Identity	Description
dag1	1.386e-18	55.56	dystroglycan 1 [Source:Xenbase;Acc:XB-GENE-1015769...	[more]
NANOS3	3.000e-17	37.76	nanos C2HC-type zinc finger 3 [Source:HGNC Symbol;...	[more]
ENSXETT00000051581.1	8.804e-15	50.00	pep primary_assembly:Xenopus_tropicalis_v9.1:1:149...	[more]
ENSXETT00000051579.1	1.135e-14	50.00	pep primary_assembly:Xenopus_tropicalis_v9.1:1:149...	[more]

BLAST of nanos-like protein vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 4


Match Name	E-value	Identity	Description
Nanos1	2.159e-21	51.35	nanos C2HC-type zinc finger 1 [Source:MGI Symbol;A...	[more]
Nanos2	7.712e-18	51.61	nanos C2HC-type zinc finger 2 [Source:MGI Symbol;A...	[more]
Nanos3	1.332e-15	42.86	nanos C2HC-type zinc finger 3 [Source:MGI Symbol;A...	[more]
Nanos3	1.389e-15	42.86	nanos C2HC-type zinc finger 3 [Source:MGI Symbol;A...	[more]

BLAST of nanos-like protein vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5


Match Name	E-value	Identity	Description
sp\|E7FDB3\|NANO1_DANRE	7.843e-21	55.07	Nanos homolog 1 OS=Danio rerio OX=7955 GN=nanos1 P...	[more]
sp\|Q80WY3\|NANO1_MOUSE	1.510e-20	51.35	Nanos homolog 1 OS=Mus musculus OX=10090 GN=Nanos1...	[more]
sp\|Q8WY41\|NANO1_HUMAN	4.648e-20	57.38	Nanos homolog 1 OS=Homo sapiens OX=9606 GN=NANOS1 ...	[more]
sp\|Q07937\|NANO1_XENLA	1.348e-19	57.41	Nanos homolog 1 OS=Xenopus laevis OX=8355 GN=nanos...	[more]
sp\|Q90ZZ5\|NANO1_XENBO	3.119e-19	57.41	Nanos homolog 1 OS=Xenopus borealis OX=8354 GN=nan...	[more]

BLAST of nanos-like protein vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5


Match Name	E-value	Identity	Description
A4UCR6	2.015e-156	99.57	Nanos-like protein OS=Schmidtea mediterranea OX=79...	[more]
A5Y5A4	2.093e-141	99.53	Nanos-like protein OS=Schmidtea mediterranea OX=79...	[more]
F8WTH7	4.024e-96	81.36	Nanos-related protein OS=Dugesia ryukyuensis OX=79...	[more]
Q5H7Z0	7.187e-96	81.36	Nanos-related protein OS=Dugesia japonica OX=6161 ...	[more]
A0A068W982	1.844e-28	50.96	Nanos protein OS=Echinococcus granulosus OX=6210 G...	[more]

BLAST of nanos-like protein vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 4


Match Name	E-value	Identity	Description
NANOS1	1.909e-22	52.11	nanos C2HC-type zinc finger 1 [Source:HGNC Symbol;...	[more]
ENSAMXT00000053799.1	1.432e-21	58.73	pep primary_assembly:Astyanax_mexicanus-2.0:24:937...	[more]
nanos2	4.943e-18	52.38	nanos homolog 2 [Source:ZFIN;Acc:ZDB-GENE-130321-1...	[more]
ENSAMXT00000056869.1	6.354e-14	46.77	nanos homolog 1 [Source:NCBI gene;Acc:103030775]	[more]

BLAST of nanos-like protein vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 1


Match Name	E-value	Identity	Description
ENSPMAT00000011356.1	1.988e-20	60.71	pep scaffold:Pmarinus_7.0:GL477149:1779:2000:1 gen...	[more]

BLAST of nanos-like protein vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 0


Match Name	E-value	Identity	Description

BLAST of nanos-like protein vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 2


Match Name	E-value	Identity	Description
NOS1	1.955e-21	50.00	Nanos 1; Predicted protein [Source:UniProtKB/TrEM...	[more]
EDO49152	2.828e-12	60.00	Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7...	[more]

BLAST of nanos-like protein vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 3


Match Name	E-value	Identity	Description
nanos1a	1.260e-20	55.38	nanos1 [Source:NCBI gene;Acc:100144352]	[more]
nanos2	7.588e-18	55.17	nanos2 protein [Source:NCBI gene;Acc:100301601]	[more]
nanos3	2.714e-13	51.85	nanos C2HC-type zinc finger 3 [Source:NCBI gene;Ac...	[more]

BLAST of nanos-like protein vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 2


Match Name	E-value	Identity	Description
SMESG000018169.1	5.603e-160	99.57	SMESG000018169.1	[more]
SMESG000018169.1	1.163e-153	97.42	SMESG000018169.1	[more]

Analyses

This transcript is derived from or has results from the following analyses


Analysis Name	Date Performed
Embryonic Stages	2016-07-25
Schmidtea mediterranea smed_20140614 BLASTX Human e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99	2016-08-08
Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL	2020-05-01
Schmidtea mediterranea Sexual smed_20140614 transcriptome	2016-07-25
Schmidtea mediteranean smed_20140614 Interproscan	2020-05-01
Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99	2020-05-08
Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST	2020-05-08

Cross References

External references for this transcript


Database	Accession
SmedGD GBrowse	SMED30034750
GenBank	ABO52809.1

Sequences

The following sequences are available for this feature:

transcript sequence
protein sequence

transcript sequence

>SMED30034750 ID=SMED30034750|Name=nanos-like protein|organism=Schmidtea mediterranea sexual|type=transcript|length=791bp
CAATTTTATAATTTGAATTGGTTTTTTTCTCATGCGCACAGGCGAATCAT
ATTTCGTTTTAATTCATCACACACTAAAGCTTAATTTAATGTTAAATCAT
CCTGAATCATTGAAGATGGCTAATACGTCTCCATTTATTTGGCAATCAGT
GACATCTAACAATGTGTCTTATAGTAGCAATAAATCCAATGTTAATTATC
CAAGGACAAATGTTGCCTGTATATTACCGAATTTATTGCAAAAAAATATT
GCAAAGACAGATTTTTCACTGTTAGATGAAGAAGATAATGACAGTTTATT
TCGCAGCGATTTAAAATTATCAAAGGAGTTGGATCGATGGGTTGCATTGT
TGGAAGCATGGCCTGAAAAGCATATTACTCTGGATAGAAGTATATGGCTA
AGGTTATTGCACAAACTTAGAACATCTAATCAAATTCGCAAAGAAAGTCA
TATTGAACTATGTGTCTTCTGTAGGAATAACAATGAACCTTTTGAAATGT
ATGTTAGTCATAAAGTTAAAGACCTAAATGGTAAGGTTACATGTCCAGTT
CTACGTAATTATACATGCCCATTGTGTAACAGTACAGGTGACTTTGCTCA
TACAATCAAATATTGTCCCATTTCTATGAATACAACAAAACAAGTGTCAG
ATAATTCTTTGGAAGAAATTACAAGAAATCAAATTGCTATTAAATCAAGA
AGCATGTCACAATCCACTCTTGGTATAGCTTAAAGGAAGAAATTGTTAAA
TGTTTTAAGGCTTATGAATCAATGTTATATGATTGTCAATG

protein sequence of SMED30034750-orf-1

>SMED30034750-orf-1 ID=SMED30034750-orf-1|Name=SMED30034750-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=234bp
MRTGESYFVLIHHTLKLNLMLNHPESLKMANTSPFIWQSVTSNNVSYSSN
KSNVNYPRTNVACILPNLLQKNIAKTDFSLLDEEDNDSLFRSDLKLSKEL
DRWVALLEAWPEKHITLDRSIWLRLLHKLRTSNQIRKESHIELCVFCRNN
NEPFEMYVSHKVKDLNGKVTCPVLRNYTCPLCNSTGDFAHTIKYCPISMN
TTKQVSDNSLEEITRNQIAIKSRSMSQSTLGIA*

Aliases

The feature 'nanos-like protein' has the following synonyms


Synonym
nos

Annotated Terms

The following terms have been associated with this transcript:

Vocabulary: **Planarian Anatomy**
Term	Definition
PLANA:0000204	ovary
PLANA:0000208	testis
PLANA:0000220	spermatogonium
PLANA:0000239	oogonial cell
PLANA:0000419	prepharyngeal region
PLANA:0000429	neoblast
PLANA:0002030	early male germ cell
PLANA:0002109	X1 cell
PLANA:0003301	eye primordium
PLANA:0003304	testis primordium
PLANA:0003305	gonad primoridium

Vocabulary: **INTERPRO**
Term	Definition
IPR038129	Nanos_sf
IPR008705	Nanos/Xcar2
IPR024161	Znf_nanos-typ

Vocabulary: **molecular function**
Term	Definition
GO:0003723	RNA binding
GO:0008270	zinc ion binding

Vocabulary: **biological process**
Term	Definition
GO:0006417	regulation of translation

InterPro

Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR038129	Nanos domain superfamily	GENE3D	G3DSA:1.10.150.680		coord: 141..210 e-value: 2.7E-28 score: 99.7
IPR024161	Zinc finger, nanos-type	PFAM	PF05741	zf-nanos	coord: 144..196 e-value: 1.9E-24 score: 85.6
IPR024161	Zinc finger, nanos-type	PROSITE	PS51522	ZF_NANOS	coord: 143..197 score: 23.867
IPR008705	Nanos/Xcat2	PANTHER	PTHR12887	NANOS PROTEIN	coord: 138..211

Main menu

nanos-like protein

Zeng et. al., 2018

▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Overview

Single cell RNA-seq of pluripotent neoblasts and its early progenies

Explore this single cell expression dataset with our NB Cluster Shiny App

Neoblast Population

Sub-lethal Irradiated Surviving X1 and X2 Cell Population

Davies et. al., 2017

PAGE et. al., 2020

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE

PAGE Curations: 28

Owlery

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