Serine/threonine-protein kinase PLK

Overview
NameSerine/threonine-protein kinase PLK
Smed IDSMED30034742
Length (bp)1388
Neoblast Clusters

Zeng et. al., 2018



▻ Overview

▻ Neoblast Population

▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

 

Overview

 

Single cell RNA-seq of pluripotent neoblasts and its early progenies


We isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.

We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)



Explore this single cell expression dataset with our NB Cluster Shiny App



 

Neoblast Population

 

t-SNE plot shows two-dimensional representation of global gene expression relationships among all neoblasts (n = 7,088 after filter). Cluster identity was assigned based on the top 10 marker genes of each cluster (Table S2), followed by inspection of RNA in situ hybridization patterns. Neoblast groups, Nb.


Expression of Serine/threonine-protein kinase PLK (SMED30034742) t-SNE clustered cells

Violin plots show distribution of expression levels for Serine/threonine-protein kinase PLK (SMED30034742) in cells (dots) of each of the 12 neoblast clusters.

 

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Sub-lethal Irradiated Surviving X1 and X2 Cell Population

 

t-SNE plot of surviving X1 and X2 cells (n = 1,039 after QC filter) after sub-lethal irradiation. Colors indicate unbiased cell classification via graph-based clustering. SL, sub-lethal irradiated cell groups.

Expression of Serine/threonine-protein kinase PLK (SMED30034742) in the t-SNE clustered sub-lethally irradiated X1 and X2 cells.

Violin plots show distribution of expression levels for Serine/threonine-protein kinase PLK (SMED30034742) in cells (dots) of each of the 10 clusters of sub-leathally irradiated X1 and X2 cells.

 

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Embryonic Expression

Davies et. al., 2017

Hover the mouse over a column in the graph to view average RPKM values per sample.
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Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult.
For further information about sample preparation and analysis for the single animal RNA-Seq experiment, please refer to the Materials and Methods

 

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Anatomical Expression

PAGE et. al., 2020



SMED30034742

has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGE



PAGE Curations: 5

  
Expressed InReference TranscriptGene ModelsPublished TranscriptTranscriptomePublicationSpecimenLifecycleEvidence
X1 cellSMED30034742SMESG000007751.1 SmedASXL_004653SmedAsxl_ww_GCZZ01PMID:26114597
Zhu et al., 2015		FACS sorted cell population asexual adult RNA-sequencing evidence
whole organismSMED30034742SMESG000007751.1 Contig42043newmark_estsPMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
whole organismSMED30034742SMESG000007751.1 Contig42043uc_Smed_v2PMID:27612384
Roberts-Galbraith et al., 2016		whole organism asexual adult colorimetric in situ hybridization evidence
reproductive organSMED30034742SMESG000007751.1 Contig42043newmark_estsPMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
reproductive organSMED30034742SMESG000007751.1 Contig42043uc_Smed_v2PMID:28434803
Rouhana et al., 2017		whole organism adult hermaphrodite RNA-sequencing evidence
Note: Hover over icons to view figure legend
Homology
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Human
Match: PLK1 (polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077])

HSP 1 Score: 238.039 bits (606), Expect = 2.773e-71
Identity = 133/363 (36.64%), Postives = 203/363 (55.92%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL----------LQDG---QIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RN 1306
            +W+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L          L  G    + + P+  EE    +  +         ++ +  +  S P        +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL+L  +  + QYI     E + TV   P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN ++Q+NF +DH KL+LCP M +V  IDE  + +TY+LS L   G  ++L S+  +  ++++  +S R+
Sbjct:  234 VWSIG-CIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRS 595
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Human
Match: PLK3 (polo like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2154])

HSP 1 Score: 98.2117 bits (243), Expect = 3.096e-21
Identity = 56/172 (32.56%), Postives = 86/172 (50.00%), Query Frame = 2 
Query:  740 PIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLC---PFMGSVMIIDENSEIKTYKLSSLHGNGITED 1246
            P+ WVSKWVD ++++G  Y L+      +FND T + L+ N     Y   S +   ++V   P  ++ ++ ++R   +YM  HLM  GGDL   E+  +   P L Q+     A+  + S+ T+QVNF  DH KL+L    P +  V  +  N    TY  S L   G + D
Sbjct:  460 PLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSVGAVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEVEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPD 628

HSP 2 Score: 69.3218 bits (168), Expect = 7.177e-12
Identity = 33/89 (37.08%), Postives = 54/89 (60.67%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSC 544
            +W++     YTL+ G PPFET+++ +TYR I  + Y +P  L    ++++ ++L+     RP++  +L   FF KG+TP  LPIS  SC
Sbjct:  243 VWSLG-CVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIDQILRHDFFTKGYTPDRLPIS--SC 328
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Human
Match: PLK2 (polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699])

HSP 1 Score: 91.6633 bits (226), Expect = 4.264e-19
Identity = 53/183 (28.96%), Postives = 100/183 (54.64%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDL-VVSEQDSMIRLPNLR--QFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+D++ G +FN+   + L P+     Y     Q   +   D PE+   +V +++   +YM  +LM  GGDL  V++    IR P L   Q+     A+  + ++ T QVNF  DH K+++C      ++  I+E+    T++L++L  +G + +L ++  + ++++
Sbjct:  489 WVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMD-GGDLPSVTD----IRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLMSGCSSELKNRMEYALNML 666

HSP 2 Score: 68.5514 bits (166), Expect = 1.289e-11
Identity = 34/87 (39.08%), Postives = 51/87 (58.62%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            YT+++G+PPFET+N+ +TYR I    Y +P  L    K +I S+L ++   RP++  ++   FF +GFTP  L  S     P F LS
Sbjct:  257 YTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLS 343
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Human
Match: PLK2 (polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19699])

HSP 1 Score: 91.6633 bits (226), Expect = 4.381e-19
Identity = 53/183 (28.96%), Postives = 100/183 (54.64%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDL-VVSEQDSMIRLPNLR--QFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+D++ G +FN+   + L P+     Y     Q   +   D PE+   +V +++   +YM  +LM  GGDL  V++    IR P L   Q+     A+  + ++ T QVNF  DH K+++C      ++  I+E+    T++L++L  +G + +L ++  + ++++
Sbjct:  503 WVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMD-GGDLPSVTD----IRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICSQNEEYLLTYINEDRISTTFRLTTLLMSGCSSELKNRMEYALNML 680

HSP 2 Score: 68.5514 bits (166), Expect = 1.206e-11
Identity = 34/87 (39.08%), Postives = 51/87 (58.62%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            YT+++G+PPFET+N+ +TYR I    Y +P  L    K +I S+L ++   RP++  ++   FF +GFTP  L  S     P F LS
Sbjct:  271 YTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLS 357
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Human
Match: PLK1 (polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:9077])

HSP 1 Score: 78.1814 bits (191), Expect = 4.472e-17
Identity = 39/91 (42.86%), Postives = 58/91 (63.74%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL 577
            YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L
Sbjct:    2 YTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSL 92
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Celegans
Match: plk-1 (Serine/threonine-protein kinase plk-1 [Source:UniProtKB/Swiss-Prot;Acc:P34331])

HSP 1 Score: 199.134 bits (505), Expect = 1.028e-56
Identity = 123/371 (33.15%), Postives = 191/371 (51.48%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPISILS----------------CPPRFKLSKTELLQDGQ---------IVD-------SPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKES------ENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTV--DDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            Y L+ G+PPFE+ ++ +TY RI   +Y IP    +    +I  +L  +   RPT K +    FFK GF PT LP+S L+                  PR   ++++   +G+         IV        + Q   E T  +     L      V ++     P L +E       ++P+  P+FW+SKWVD + +YG+ Y L DNS G +FND++R++L        YI  SN+E ++++   + P  + KKV L++  ++YMN+HL+ AG        D + RLP LR +F   SAI   LSN T+Q+NF  DHVK+++CP M +V  ID+N  + TYKL++L  NG  E  L +  +  ++IE  +S
Sbjct:  227 YILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKSGFMPTRLPVSCLTMVPKFGGHETSMMEENVAPRGVDARSQRPLNGRAGLSALPQHIVSNNADRERAQQQAAEATFREPEDAYLSQLFHQVAVLLEQRIPGLEEEEAALDGYQSPECLPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIMLDQAGNELTYIEKSNKEHYFSMHSGEMPGLLNKKVTLLKYFRSYMNDHLVKAGEGSEQRAGDDLARLPTLRVWFRTKSAIVLHLSNGTVQINFFNDHVKMMMCPLMQAVTFIDQNKRMLTYKLNNLQRNGCPEKFLHRLKYAKTMIERLMS 597
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Celegans
Match: plk-1 (Serine/threonine-protein kinase plk-1 [Source:UniProtKB/Swiss-Prot;Acc:P34331])

HSP 1 Score: 198.749 bits (504), Expect = 1.065e-56
Identity = 123/371 (33.15%), Postives = 191/371 (51.48%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPISILS----------------CPPRFKLSKTELLQDGQ---------IVD-------SPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKES------ENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTV--DDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            Y L+ G+PPFE+ ++ +TY RI   +Y IP    +    +I  +L  +   RPT K +    FFK GF PT LP+S L+                  PR   ++++   +G+         IV        + Q   E T  +     L      V ++     P L +E       ++P+  P+FW+SKWVD + +YG+ Y L DNS G +FND++R++L        YI  SN+E ++++   + P  + KKV L++  ++YMN+HL+ AG        D + RLP LR +F   SAI   LSN T+Q+NF  DHVK+++CP M +V  ID+N  + TYKL++L  NG  E  L +  +  ++IE  +S
Sbjct:  226 YILLFGQPPFESKSLEETYSRIRHNNYTIPSIATQPAASLIRKMLDPEPTRRPTAKQVQRDGFFKSGFMPTRLPVSCLTMVPKFGGHETSMMEENVAPRGVDARSQRPLNGRAGLSALPQHIVSNNADRERAQQQAAEATFREPEDAYLSQLFHQVAVLLEQRIPGLEEEEAALDGYQSPECLPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIMLDQAGNELTYIEKSNKEHYFSMHSGEMPGLLNKKVTLLKYFRSYMNDHLVKAGEGSEQRAGDDLARLPTLRVWFRTKSAIVLHLSNGTVQINFFNDHVKMMMCPLMQAVTFIDQNKRMLTYKLNNLQRNGCPEKFLHRLKYAKTMIERLMS 596
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Celegans
Match: plk-2 (Serine/threonine-protein kinase plk-2 [Source:UniProtKB/Swiss-Prot;Acc:Q9N2L7])

HSP 1 Score: 164.081 bits (414), Expect = 3.713e-44
Identity = 77/192 (40.10%), Postives = 118/192 (61.46%), Query Frame = 2 
Query:  722 ENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDD-FPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTV 1294
            ++P+  P+FW+SKWVD + +YG+ Y L DNS G +FND++R++L        YI  + +E ++ ++   P  ++KK+ L++  ++YMN+HL+ AG  +     D + RLP LR +F   SAI   LSN T+Q+NF  DH+K+VLCP M +V  IDEN  + TYK S L  NG  E  L +  +   +I+  V
Sbjct:  396 QSPEALPVFWISKWVDYSDKYGIGYQLCDNSVGVLFNDNSRIMLDTAGTQLTYIEKTEKEHYFDMESAIPSGLQKKMTLLKYFRSYMNDHLLQAGQQVTRKVGDDLARLPTLRVWFRTKSAIVLHLSNGTVQINFFNDHIKMVLCPLMQAVTFIDENKRMFTYKFSHLAENGCPEKFLHRIQYAKCMIQRLV 587

HSP 2 Score: 58.9214 bits (141), Expect = 5.294e-9
Identity = 30/84 (35.71%), Postives = 45/84 (53.57%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPISILSCPPRF 556
            Y L+ G PPFE+ ++ +TY RI + +YVIP        ++I  +L    + RP  + +    FFK GF P  LP+S L+  P  
Sbjct:  224 YILLFGHPPFESKSLEETYSRIKNNNYVIPTSASAAASQLIRVLLDPVPSRRPNARAVCRDHFFKSGFMPARLPVSCLTMVPHL 307
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Celegans
Match: plk-3 (Serine/threonine-protein kinase plk-3 [Source:UniProtKB/Swiss-Prot;Acc:Q20845])

HSP 1 Score: 124.405 bits (311), Expect = 2.756e-30
Identity = 68/198 (34.34%), Postives = 114/198 (57.58%), Query Frame = 2 
Query:  719 SENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDD-FPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQ--------DSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            + +P+  PIFWVS+WV   + +G+ Y L +NS+G +FND+T++ +        ++  +N E FYT++D  P  ++ K+ +  N ++YMN HL  A   L   +Q         +  RLP ++ +F   SA+ F LSN T+Q+NF  DHVK+VLCP + SV  I+EN  + T+  +++  N   +  LS+  +  + I+
Sbjct:  383 NHSPEATPIFWVSQWVHFPN-HGIGYRLCENSSGMLFNDNTQMKVNSAGNQLTFVDENNTEQFYTMNDQVPMNLQTKINIFSNVQSYMNTHL-EADTHLEAEDQCVNKVPPLRNFARLPTIQNWFETKSAVIFHLSNGTVQINFL-DHVKMVLCPLLKSVTFIEENKRVSTFTFANILTNSCPKKYLSRIEYAQAKIK 577

HSP 2 Score: 52.7582 bits (125), Expect = 3.666e-7
Identity = 31/84 (36.90%), Postives = 43/84 (51.19%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPI 529
            IW I     Y L+ G PPFE+  + +TY RI +  YV+PE        +I S+L    + RPT + +L   FFK    PT  P+
Sbjct:  215 IWAIG-CILYVLLFGSPPFESRRVQETYVRIKNNDYVVPENASPTANRLIRSLLDPVPDRRPTAEAVLLDQFFKTTIEPTYPPV 297
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Celegans
Match: plk-3 (Serine/threonine-protein kinase plk-3 [Source:UniProtKB/Swiss-Prot;Acc:Q20845])

HSP 1 Score: 124.405 bits (311), Expect = 2.756e-30
Identity = 68/198 (34.34%), Postives = 114/198 (57.58%), Query Frame = 2 
Query:  719 SENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDD-FPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQ--------DSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            + +P+  PIFWVS+WV   + +G+ Y L +NS+G +FND+T++ +        ++  +N E FYT++D  P  ++ K+ +  N ++YMN HL  A   L   +Q         +  RLP ++ +F   SA+ F LSN T+Q+NF  DHVK+VLCP + SV  I+EN  + T+  +++  N   +  LS+  +  + I+
Sbjct:  383 NHSPEATPIFWVSQWVHFPN-HGIGYRLCENSSGMLFNDNTQMKVNSAGNQLTFVDENNTEQFYTMNDQVPMNLQTKINIFSNVQSYMNTHL-EADTHLEAEDQCVNKVPPLRNFARLPTIQNWFETKSAVIFHLSNGTVQINFL-DHVKMVLCPLLKSVTFIEENKRVSTFTFANILTNSCPKKYLSRIEYAQAKIK 577

HSP 2 Score: 52.7582 bits (125), Expect = 3.666e-7
Identity = 31/84 (36.90%), Postives = 43/84 (51.19%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPI 529
            IW I     Y L+ G PPFE+  + +TY RI +  YV+PE        +I S+L    + RPT + +L   FFK    PT  P+
Sbjct:  215 IWAIG-CILYVLLFGSPPFESRRVQETYVRIKNNDYVVPENASPTANRLIRSLLDPVPDRRPTAEAVLLDQFFKTTIEPTYPPV 297
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Fly
Match: polo (gene:FBgn0003124 transcript:FBtr0074839)

HSP 1 Score: 198.749 bits (504), Expect = 4.911e-57
Identity = 122/363 (33.61%), Postives = 186/363 (51.24%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGF-TPTCLPISILSCPPRF--------------------------KLSKTEL---LQDGQIVDSPQLL---EEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFV 1270
            IW+I     YTL++G+PPFET  + DTY +I    Y +P YL +   ++++++L+ +  SRP +  LL   F KG   P  LP S L+  PR                           +L  T L   L D  I  S Q+    E+Y +      Q    L N K    I    L  E+ +P   P+FW+SKWVD + +YG  Y L D   G +FND T+L+L PN  N  +I    +E + T  D+ + + KK+KL+   K YM  HL+ AG + V  E D + R+P+L  +F    A+   L+N ++Q+NF  DH+KL+LCP M ++  +D+    +TY+ S++  NG+++DL  K  + 
Sbjct:  206 IWSIG-CVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRIGSNDTIEDSMHRKPLMEMNGIRPDDTRLESTFLKANLHDA-ITASAQVCRHSEDYRSDIESLYQQLTNLINGK--PRILQGNLGDENTDPAAQPLFWISKWVDYSDKYGFGYQLCDEGIGVMFNDTTKLILLPNQINVHFIDKDGKETYMTTTDYCKSLDKKMKLLSYFKRYMIEHLVKAGANNVNIESDQISRMPHLHSWFRTTCAVVMHLTNGSVQLNF-SDHMKLILCPRMSAITYMDQEKNFRTYRFSTIVENGVSKDLYQKIRYA 563
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Fly
Match: polo (gene:FBgn0003124 transcript:FBtr0100318)

HSP 1 Score: 198.749 bits (504), Expect = 4.911e-57
Identity = 122/363 (33.61%), Postives = 186/363 (51.24%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGF-TPTCLPISILSCPPRF--------------------------KLSKTEL---LQDGQIVDSPQLL---EEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFV 1270
            IW+I     YTL++G+PPFET  + DTY +I    Y +P YL +   ++++++L+ +  SRP +  LL   F KG   P  LP S L+  PR                           +L  T L   L D  I  S Q+    E+Y +      Q    L N K    I    L  E+ +P   P+FW+SKWVD + +YG  Y L D   G +FND T+L+L PN  N  +I    +E + T  D+ + + KK+KL+   K YM  HL+ AG + V  E D + R+P+L  +F    A+   L+N ++Q+NF  DH+KL+LCP M ++  +D+    +TY+ S++  NG+++DL  K  + 
Sbjct:  206 IWSIG-CVMYTLLVGQPPFETKTLKDTYSKIKKCEYRVPSYLRKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRIGSNDTIEDSMHRKPLMEMNGIRPDDTRLESTFLKANLHDA-ITASAQVCRHSEDYRSDIESLYQQLTNLINGK--PRILQGNLGDENTDPAAQPLFWISKWVDYSDKYGFGYQLCDEGIGVMFNDTTKLILLPNQINVHFIDKDGKETYMTTTDYCKSLDKKMKLLSYFKRYMIEHLVKAGANNVNIESDQISRMPHLHSWFRTTCAVVMHLTNGSVQLNF-SDHMKLILCPRMSAITYMDQEKNFRTYRFSTIVENGVSKDLYQKIRYA 563
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Zebrafish
Match: plk1 (polo-like kinase 1 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-021115-7])

HSP 1 Score: 230.335 bits (586), Expect = 1.272e-68
Identity = 127/366 (34.70%), Postives = 204/366 (55.74%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL-------------------LQDGQIVDSPQL--LEEYXXXXXXXXXXXXXXXXVKIISYISHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            IW++     YTL++GKPPFETS + +TY RI    Y +P +++     +I  +L  D   RP++  LL   FF  G+ P  LP S L+ PPRF ++ + L                   ++    +D PQ   L++    +     L D L  + +++  + P        +E+E+P   P+FW+SKWVD + +YGL Y L+DNS G +FND TRL++  +  + QYI  ++ E + +V  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP MG+V  I+E  E  TYK++ +   G  ++L S+  +  +++E  ++
Sbjct:  220 IWSLG-CILYTLLVGKPPFETSCLKETYIRIKKNEYSVPRHINPVASALIRRMLHADPTLRPSVAELLTDEFFTSGYAPMRLPTSCLTVPPRFSIAPSSLDPALLRKPLSSLNKGTDSPIEKMGKMDQPQREDLQQRDGPEQPDTHLTDMLQQLAVVN-AAKPSDRDFIRQEEAEDPACIPVFWISKWVDYSDKYGLGYQLSDNSVGVLFNDSTRLIMCADGDSLQYIDRNSLESYLSVRSYPSALSKKITLLKYFRNYMSEHLLKAGANITPREGDELTRLPYLRHWFRTKSAIVLHLSNGTVQINFFQDHTKLILCPLMGAVTYINEKREFYTYKMTLIEEFGCCKELASRLRYARNMVEKLMA 583
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Zebrafish
Match: plk1 (polo-like kinase 1 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-021115-7])

HSP 1 Score: 230.335 bits (586), Expect = 1.272e-68
Identity = 127/366 (34.70%), Postives = 204/366 (55.74%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL-------------------LQDGQIVDSPQL--LEEYXXXXXXXXXXXXXXXXVKIISYISHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            IW++     YTL++GKPPFETS + +TY RI    Y +P +++     +I  +L  D   RP++  LL   FF  G+ P  LP S L+ PPRF ++ + L                   ++    +D PQ   L++    +     L D L  + +++  + P        +E+E+P   P+FW+SKWVD + +YGL Y L+DNS G +FND TRL++  +  + QYI  ++ E + +V  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP MG+V  I+E  E  TYK++ +   G  ++L S+  +  +++E  ++
Sbjct:  220 IWSLG-CILYTLLVGKPPFETSCLKETYIRIKKNEYSVPRHINPVASALIRRMLHADPTLRPSVAELLTDEFFTSGYAPMRLPTSCLTVPPRFSIAPSSLDPALLRKPLSSLNKGTDSPIEKMGKMDQPQREDLQQRDGPEQPDTHLTDMLQQLAVVN-AAKPSDRDFIRQEEAEDPACIPVFWISKWVDYSDKYGLGYQLSDNSVGVLFNDSTRLIMCADGDSLQYIDRNSLESYLSVRSYPSALSKKITLLKYFRNYMSEHLLKAGANITPREGDELTRLPYLRHWFRTKSAIVLHLSNGTVQINFFQDHTKLILCPLMGAVTYINEKREFYTYKMTLIEEFGCCKELASRLRYARNMVEKLMA 583
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Zebrafish
Match: plk3 (polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-6134])

HSP 1 Score: 103.219 bits (256), Expect = 4.741e-23
Identity = 63/196 (32.14%), Postives = 101/196 (51.53%), Query Frame = 2 
Query:  719 SENP----KLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLC-PFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            S NP    K  P  WV+KWVD +++YG  Y L++ + G +FN+ T L L        Y   +N+   +  +  PEK++ +  ++    NYM  +LM  GGD+   +Q S    P L Q+     A+  +  N TLQVNF  DH K++LC P   S ++  I +     +Y L+ L   G + +L  + H+VV +++
Sbjct:  462 SRNPPCLVKTKPFIWVTKWVDYSNKYGFGYQLSNQNVGVLFNEGTHLSLCDQRRTVHYCLTNNKHFSFPANALPEKLQSQKHIVDLMANYMEQNLM-EGGDINCEDQ-SSSSSPLLLQWIKTDHALVMLFDNRTLQVNFYTDHTKIILCKPSDASYLVTFISKERVSYSYPLNVLSELGCSPELRQRLHYVVQLLQ 655

HSP 2 Score: 61.2326 bits (147), Expect = 1.485e-9
Identity = 33/89 (37.08%), Postives = 53/89 (59.55%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSC 544
            +W++     YTL+ G PPFET ++ +TY+ I  + Y +P  L    +++I S+L+++   R T+  +L   +F KGFTP  LP S  SC
Sbjct:  240 VWSLG-CVMYTLLCGNPPFETLDLKETYKCIKEVKYSLPSSLTPSAQKLISSILQKNPCDRLTLDQILAHDYFTKGFTPEKLPPS--SC 325
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Zebrafish
Match: plk2b (polo-like kinase 2b (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-070720-17])

HSP 1 Score: 102.064 bits (253), Expect = 1.107e-22
Identity = 58/180 (32.22%), Postives = 95/180 (52.78%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+DN+ G +FN  T + L  +           Q+  ++V + PE     V +++   +YM  +LM  GGD V+SE D       L Q+     A+  + ++ T QVNF  DH KL+LC      ++  I+E     T++LS+L   G T DL S+  + ++++
Sbjct:  475 WVTKWVDYSNKYGFGYQLSDNTVGVLFNSGTHMSLLSDKKTVHQYAALGQKSVFSVIEAPECAVAHVTILKYFAHYMEENLMD-GGD-VISEPDIQKTRIYLLQWLKSDRALLMLFNDGTFQVNFYHDHTKLILCTQQDEYLLTYINEERTSATFQLSTLLSAGCTADLRSRLEYALNML 652

HSP 2 Score: 68.9366 bits (167), Expect = 5.219e-12
Identity = 33/87 (37.93%), Postives = 51/87 (58.62%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            YT+++GKPPFET+N+ +TYR I    Y +P  L    K++I  +L ++   RP +  ++   FF +GF P  LP+S     P F +S
Sbjct:  243 YTMLLGKPPFETTNLKETYRCIREARYTLPSSLSLPAKQLISGMLAQNPVDRPHLDDIIRHEFFTQGFMPETLPVSCCLSAPDFHIS 329
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Zebrafish
Match: plk2b (polo-like kinase 2b (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-070720-17])

HSP 1 Score: 102.064 bits (253), Expect = 1.107e-22
Identity = 58/180 (32.22%), Postives = 95/180 (52.78%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+DN+ G +FN  T + L  +           Q+  ++V + PE     V +++   +YM  +LM  GGD V+SE D       L Q+     A+  + ++ T QVNF  DH KL+LC      ++  I+E     T++LS+L   G T DL S+  + ++++
Sbjct:  475 WVTKWVDYSNKYGFGYQLSDNTVGVLFNSGTHMSLLSDKKTVHQYAALGQKSVFSVIEAPECAVAHVTILKYFAHYMEENLMD-GGD-VISEPDIQKTRIYLLQWLKSDRALLMLFNDGTFQVNFYHDHTKLILCTQQDEYLLTYINEERTSATFQLSTLLSAGCTADLRSRLEYALNML 652

HSP 2 Score: 68.9366 bits (167), Expect = 5.219e-12
Identity = 33/87 (37.93%), Postives = 51/87 (58.62%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            YT+++GKPPFET+N+ +TYR I    Y +P  L    K++I  +L ++   RP +  ++   FF +GF P  LP+S     P F +S
Sbjct:  243 YTMLLGKPPFETTNLKETYRCIREARYTLPSSLSLPAKQLISGMLAQNPVDRPHLDDIIRHEFFTQGFMPETLPVSCCLSAPDFHIS 329
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Xenopus
Match: plk1 (polo like kinase 1 [Source:NCBI gene;Acc:407937])

HSP 1 Score: 241.891 bits (616), Expect = 7.634e-73
Identity = 133/346 (38.44%), Postives = 198/346 (57.23%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPISILSCPPRFKLSKTELLQD----------GQIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            IW+I     YTL++GKPPFETS + +TY RI    Y +P++++     +I  +L+ +  SRPT+  LL   FF  G+ P+ LP + L+ PPRF ++ + + Q           GQ  DSP L+E +                ++   Y S     +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  +N E +  V  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDE  E  TYKLS +   G  ++L S+  +  +++E
Sbjct:  245 IWSIG-CIMYTLLVGKPPFETSCLKETYMRIKKNEYSVPKHINPMATALIQKMLRSEPTSRPTIDDLLNDEFFTTGYIPSRLPTTCLTVPPRFSIAPSTIDQSLRKPLTAINKGQ--DSP-LVENWEY--------------IEASEYNSCCSFSEEAEDPASVPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIERNNSESYLNVRSYPAALTKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPFLRTWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVSYIDEKREFHTYKLSLIQEFGCCKELASRLRYARTMVE 572
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Xenopus
Match: plk1 (polo like kinase 1 [Source:NCBI gene;Acc:407937])

HSP 1 Score: 235.343 bits (599), Expect = 2.298e-70
Identity = 130/359 (36.21%), Postives = 202/359 (56.27%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPISILSCPPRFKLSKTEL-------------LQDGQIVDS---PQLLEEYXXXXXXXXXXXXXXXXVKIISYI-----SHPYLMK--ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            IW+I     YTL++GKPPFETS + +TY RI    Y +P++++     +I  +L+ +  SRPT+  LL   FF  G+ P+ LP + L+ PPRF ++ + +              QD  +V+    P   EE    +  +         ++ ++ +     S   +++  E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  +N E +  V  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDE  E  TYKLS +   G  ++L S+  +  +++E
Sbjct:  225 IWSIG-CIMYTLLVGKPPFETSCLKETYMRIKKNEYSVPKHINPMATALIQKMLRSEPTSRPTIDDLLNDEFFTTGYIPSRLPTTCLTVPPRFSIAPSTIDQSLRKPLTAINKGQDSPLVEKQSVPAKEEEMQQPESTEPADCYLSEMLQQLTCVNAVKPSERAVIRQEEAEDPASVPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIERNNSESYLNVRSYPAALTKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPFLRTWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVSYIDEKREFHTYKLSLIQEFGCCKELASRLRYARTMVE 582
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Xenopus
Match: plk1 (polo like kinase 1 [Source:NCBI gene;Acc:407937])

HSP 1 Score: 234.958 bits (598), Expect = 2.366e-70
Identity = 130/359 (36.21%), Postives = 202/359 (56.27%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK-GFTPTCLPISILSCPPRFKLSKTEL-------------LQDGQIVDS---PQLLEEYXXXXXXXXXXXXXXXXVKIISYI-----SHPYLMK--ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            IW+I     YTL++GKPPFETS + +TY RI    Y +P++++     +I  +L+ +  SRPT+  LL   FF  G+ P+ LP + L+ PPRF ++ + +              QD  +V+    P   EE    +  +         ++ ++ +     S   +++  E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  +N E +  V  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDE  E  TYKLS +   G  ++L S+  +  +++E
Sbjct:  213 IWSIG-CIMYTLLVGKPPFETSCLKETYMRIKKNEYSVPKHINPMATALIQKMLRSEPTSRPTIDDLLNDEFFTTGYIPSRLPTTCLTVPPRFSIAPSTIDQSLRKPLTAINKGQDSPLVEKQSVPAKEEEMQQPESTEPADCYLSEMLQQLTCVNAVKPSERAVIRQEEAEDPASVPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIERNNSESYLNVRSYPAALTKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPFLRTWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVSYIDEKREFHTYKLSLIQEFGCCKELASRLRYARTMVE 570
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Xenopus
Match: plk3 (polo-like kinase 3 [Source:NCBI gene;Acc:448451])

HSP 1 Score: 148.673 bits (374), Expect = 1.974e-38
Identity = 108/365 (29.59%), Postives = 178/365 (48.77%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSC-------PPR-------------FKLSKTELLQDGQIVDSP--QLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESE-NP----KLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            IW++     YTL+ G PPFETS++ +TYR I  + Y +P  L    K +++ +LKR    R T+  +LE  FF KG+TP  LP S  SC       PP              F  +K++ +       SP   L EE +   + +             S +S     ++SE NP    K     WVSKWVD +++YG  Y L++ S G +FN  T +VL  +  +  Y   +++   +     PE+++ ++ +++    YM  +LM  GGDL   E+ S   L  L Q+     A+  + SN TLQVNF  DH K++LC    + ++  I+ +   +T+ L++L   G + ++  +  + V +++
Sbjct:  249 IWSLG-CVMYTLLCGTPPFETSDLKETYRCIKQVKYTLPACLSSAAKHLLMGILKRTPGERLTLDQILEHEFFTKGYTPDKLPPS--SCVMVPDLHPPNPAKSLFTKVAKSLFGKTKSKSIHAVSANSSPVDTLTEEASGKSVSRSIRG---------SLVSSSDAFEDSEGNPTSLAKPEHFVWVSKWVDYSNKYGFGYQLSNRSIGVLFNSGTHMVLPAHRRHVHYNLTNSRHFVFPTSAVPEQLQGQMSILQYFATYMEKNLM-KGGDLPCHEEGSQTPL-LLLQWVKTEHALLMLFSNGTLQVNFYNDHTKIILCKPQDAYLLTYINRDRNSQTFLLNTLTQTGCSSEMYHRLRYTVKLLQ 599
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Xenopus
Match: plk2 (polo-like kinase 2 [Source:NCBI gene;Acc:100125189])

HSP 1 Score: 115.546 bits (288), Expect = 6.303e-27
Identity = 88/363 (24.24%), Postives = 164/363 (45.18%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFT-----PTCL---PISILSCPPRFKLSKTELLQDGQIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLA---------------------------PIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            YT+++G+PPFET+N+ +TYR I    Y +P  L    K +I S+L R+   RP +  + +  FF +GFT     P+C    P   LS P +    K      G   +  + L+ ++    +          + +  ++     +++S    +A                              WV+KWVD +++YG  Y L+D++ G +FN+   + L P+     Y         +   + PE+   +V +++   +YM  +LM  GGDL         RL  L Q+     A+  + ++ T QVNF  DH K+++       ++  I+E+    T++L++L  +G + DL ++  + ++++
Sbjct:  252 YTMLLGRPPFETTNLKETYRCIREARYSLPSSLMTSAKHLIASMLSRNPEDRPNLDEITQHDFFTQGFTPERLPPSCCHTAPDFHLSSPAKNFFKKAAAALFGGKKEKSKYLDNHSKYSNILHIGYTVDVQLYMFFFLG----LEDSTMGTVADTVARVLRGCLENMPDADAIPKEQIDTSFHWVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMNLLPDKKTVHYYAELGPCSVFPATEAPEQFISQVTVLKYFSHYMEENLMD-GGDLPSVTDVCRPRL-YLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIIANQNDEYLLTYINEDRMSTTFRLNTLLISGGSSDLKNRMEYALNML 608
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Mouse
Match: Plk1 (polo like kinase 1 [Source:MGI Symbol;Acc:MGI:97621])

HSP 1 Score: 238.81 bits (608), Expect = 1.213e-71
Identity = 134/363 (36.91%), Postives = 203/363 (55.92%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL----------LQDG---QIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RN 1306
            +W+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L          L  G    + D P+  EE    +  +         ++ ++ +  S P        +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL+L  +  + QYI     E + TV   P  + KK+ L+   +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP M +V  I+E  + +TY+LS L   G  ++L S+  +  ++++  +S R+
Sbjct:  234 VWSIG-CIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSSRKPLKVLNKGVENPLPDRPREKEEPVVRETNEAIECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRS 595
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Mouse
Match: Plk3 (polo like kinase 3 [Source:MGI Symbol;Acc:MGI:109604])

HSP 1 Score: 97.8265 bits (242), Expect = 2.777e-21
Identity = 55/172 (31.98%), Postives = 86/172 (50.00%), Query Frame = 2 
Query:  740 PIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLC---PFMGSVMIIDENSEIKTYKLSSLHGNGITED 1246
            P+ WVSKWVD ++++G  Y L+      +FND T + L+ N     Y   S +   +++   P  ++ ++ ++R   +YM  HLM  GGDL   E+  +   P L Q+     A+  + S+ T+QVNF  DH KL+L    P +  V  +  N    TY  S L   G + D
Sbjct:  424 PLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSMGSVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEAEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPD 592

HSP 2 Score: 69.3218 bits (168), Expect = 4.377e-12
Identity = 32/89 (35.96%), Postives = 55/89 (61.80%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSC 544
            +W++     YTL+ G PPFET+++ +TYR I  + Y +P  L    ++++ ++L+     RP+++ +L   FF KG+TP  LP+S  SC
Sbjct:  223 VWSLG-CVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTPDRLPVS--SC 308
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Mouse
Match: Plk3 (polo like kinase 3 [Source:MGI Symbol;Acc:MGI:109604])

HSP 1 Score: 97.8265 bits (242), Expect = 2.821e-21
Identity = 55/172 (31.98%), Postives = 86/172 (50.00%), Query Frame = 2 
Query:  740 PIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLC---PFMGSVMIIDENSEIKTYKLSSLHGNGITED 1246
            P+ WVSKWVD ++++G  Y L+      +FND T + L+ N     Y   S +   +++   P  ++ ++ ++R   +YM  HLM  GGDL   E+  +   P L Q+     A+  + S+ T+QVNF  DH KL+L    P +  V  +  N    TY  S L   G + D
Sbjct:  462 PLVWVSKWVDYSNKFGFGYQLSSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSMGSVPRALQPQLGILRYFASYMEQHLMK-GGDLPSVEEAEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEPLL--VTFVARNRSACTYLASHLRQLGCSPD 630

HSP 2 Score: 69.3218 bits (168), Expect = 4.365e-12
Identity = 32/89 (35.96%), Postives = 55/89 (61.80%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSC 544
            +W++     YTL+ G PPFET+++ +TYR I  + Y +P  L    ++++ ++L+     RP+++ +L   FF KG+TP  LP+S  SC
Sbjct:  244 VWSLG-CVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPRDRPSIEQILRHDFFTKGYTPDRLPVS--SC 329
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Mouse
Match: Plk2 (polo like kinase 2 [Source:MGI Symbol;Acc:MGI:1099790])

HSP 1 Score: 90.5077 bits (223), Expect = 8.322e-19
Identity = 53/183 (28.96%), Postives = 100/183 (54.64%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDL-VVSEQDSMIRLPNLR--QFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+D++ G +FN+   + L P+     Y     Q   +   D PE+   +V +++   +YM  +LM  GGDL  V++    IR P L   Q+     A+  + ++ T QVNF  DH K+++C      ++  I+E+    T++L++L  +G + +L ++  + ++++
Sbjct:  500 WVTKWVDYSNKYGFGYQLSDHTVGVLFNNGAHMSLLPDKKTVHYYAELGQCSVFPATDAPEQFISQVTVLKYFSHYMEENLMD-GGDLPSVTD----IRRPRLYLLQWLKSDKALMMLFNDGTFQVNFYHDHTKIIICNQSEEYLLTYINEDRISTTFRLTTLLMSGCSLELKNRMEYALNML 677

HSP 2 Score: 68.5514 bits (166), Expect = 7.434e-12
Identity = 36/96 (37.50%), Postives = 54/96 (56.25%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            IW +     YT+++G+PPFET+N+ +TYR I    Y +P  L    K +I S+L ++   RP++  ++   FF +GFTP  L  S     P F LS
Sbjct:  260 IWALG-CVMYTMLLGRPPFETTNLKETYRCIREARYTMPSSLLAPAKHLIASMLSKNPEDRPSLDDIIRHDFFLQGFTPDRLSSSCCHTVPDFHLS 354
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Mouse
Match: Plk5 (polo like kinase 5 [Source:MGI Symbol;Acc:MGI:3026984])

HSP 1 Score: 72.4034 bits (176), Expect = 4.229e-13
Identity = 39/139 (28.06%), Postives = 65/139 (46.76%), Query Frame = 2 
Query:  740 PIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPN--LRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVL 1150
            P+ W  KWVD + +YG  Y L+D  +G +F D + + L P   +  Y         +T+ D P  ++ K+ ++R    YM   L   G   + +   S    P+  L  F  +  A+  + SN T+QV+ +    +LVL
Sbjct:  410 PVLWAPKWVDYSLKYGFGYQLSDGGSGVLFRDGSHMALRPQGGHVSYQPDQGTLWTFTLRDVPSPLRAKLAVLRLFACYMQRRLREEGTVPMPATPAS----PDISLLSFIADSQAMVMLFSNGTVQVSLKTSQTQLVL 544

HSP 2 Score: 58.5362 bits (140), Expect = 1.139e-8
Identity = 31/93 (33.33%), Postives = 48/93 (51.61%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRF 556
            IW +     YT++ G PPF  + +++ Y+ I    Y+ P +L    + +I  +L  D   RP++  LL+  FF +GFTP  LP      PP F
Sbjct:  208 IWALG-CIMYTVLTGTPPFAAAPLSEMYQNIRDGHYLEPTHLSPSARSLIARLLAPDPAERPSLDHLLQDDFFSQGFTPERLPPHSCHSPPVF 299
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. UniProt/SwissProt
Match: sp|Q62673|PLK1_RAT (Serine/threonine-protein kinase PLK1 OS=Rattus norvegicus OX=10116 GN=Plk1 PE=2 SV=2)

HSP 1 Score: 238.81 bits (608), Expect = 7.718e-71
Identity = 134/363 (36.91%), Postives = 203/363 (55.92%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL----------LQDG---QIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RN 1306
            +W+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L          L  G    + D P+  EE    +  +         ++ ++ +  S P        +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL+L  +  + QYI     E + TV   P  + KK+ L+   +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP M +V  I+E  + +TY+LS L   G  ++L S+  +  ++++  +S R+
Sbjct:  234 VWSIG-CIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGVENPLPDRPREKEEPVVRETNEAIECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRS 595
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. UniProt/SwissProt
Match: sp|Q07832|PLK1_MOUSE (Serine/threonine-protein kinase PLK1 OS=Mus musculus OX=10090 GN=Plk1 PE=1 SV=2)

HSP 1 Score: 238.81 bits (608), Expect = 8.482e-71
Identity = 134/363 (36.91%), Postives = 203/363 (55.92%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL----------LQDG---QIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RN 1306
            +W+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L          L  G    + D P+  EE    +  +         ++ ++ +  S P        +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL+L  +  + QYI     E + TV   P  + KK+ L+   +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP M +V  I+E  + +TY+LS L   G  ++L S+  +  ++++  +S R+
Sbjct:  234 VWSIG-CIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSSRKPLKVLNKGVENPLPDRPREKEEPVVRETNEAIECHLSDLLQQLTSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLNYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFQTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRS 595
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. UniProt/SwissProt
Match: sp|Q2TA25|PLK1_BOVIN (Serine/threonine-protein kinase PLK1 OS=Bos taurus OX=9913 GN=PLK1 PE=2 SV=2)

HSP 1 Score: 238.424 bits (607), Expect = 1.035e-70
Identity = 133/363 (36.64%), Postives = 204/363 (56.20%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL----------LQDGQ---IVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RN 1306
            +W+I     YTL++GKPPFETS + +TY RI +  Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L          L  G    + + P+  EE    +  +         ++ +  +  S P        +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL+L  +  + QYI     E + TV   P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN  +Q+NF +DH KL+LCP M +V  IDE  + +TY+LS L   G +++L S+  +  ++++  +S R+
Sbjct:  232 VWSIG-CIMYTLLVGKPPFETSCLKETYLRIKNNEYSIPKHINPVASSLIKKMLQPDPTARPTIHELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGMENPMPERPREKEEPVVREASEPVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYSDGDSLQYIERDGSESYLTVSSHPNSLIKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGCVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCSKELASRLRYARAMVDKLLSSRS 593
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. UniProt/SwissProt
Match: sp|P53350|PLK1_HUMAN (Serine/threonine-protein kinase PLK1 OS=Homo sapiens OX=9606 GN=PLK1 PE=1 SV=1)

HSP 1 Score: 238.039 bits (606), Expect = 1.332e-70
Identity = 133/363 (36.64%), Postives = 203/363 (55.92%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL----------LQDG---QIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RN 1306
            +W+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LPI+ L+ PPRF ++ + L          L  G    + + P+  EE    +  +         ++ +  +  S P        +E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL+L  +  + QYI     E + TV   P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN ++Q+NF +DH KL+LCP M +V  IDE  + +TY+LS L   G  ++L S+  +  ++++  +S R+
Sbjct:  234 VWSIG-CIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRS 595
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. UniProt/SwissProt
Match: sp|P70032|PLK1_XENLA (Serine/threonine-protein kinase PLK1 OS=Xenopus laevis OX=8355 GN=plk1 PE=1 SV=1)

HSP 1 Score: 237.269 bits (604), Expect = 2.249e-70
Identity = 132/359 (36.77%), Postives = 203/359 (56.55%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL-------------LQDGQIVD---SPQLLEEYXXXXXXXXXXXXXXXXVKIISYI-----SHPYLMK--ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            IW+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  SRPT+  LL   FF  G+ P+ LP + L+ PPRF ++ + +              QD  +V+   +P   EE    +  +         ++ ++ +     S   L++  E+E+P   PIFW+SKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  +N E +  V  +P  + KK+ L++  +NYM+ HL+ AG +    E D + RLP LR +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDE  E +TYKLS +   G  ++L S+  +  +++E
Sbjct:  225 IWSIG-CIMYTLLVGKPPFETSCLKETYMRIKKNEYSIPKHINPVAAALIQKMLRSDPTSRPTIDDLLNDEFFTSGYIPSRLPTTCLTVPPRFSIAPSTIDQSLRKPLTAINKGQDSPLVEKQVAPAKEEEMQQPEFTEPADCYLSEMLQQLTCLNAVKPSERALIRQEEAEDPASIPIFWISKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIERNNTESYLNVRSYPTTLTKKITLLKYFRNYMSEHLLKAGANTTPREGDELARLPFLRTWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVSYIDEKREFRTYKLSLIQEFGCCKELASRLRYARTMVE 582
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. TrEMBL
Match: A0A2I0LX11 (Polo-like kinase 1 OS=Columba livia OX=8932 GN=PLK1 PE=4 SV=1)

HSP 1 Score: 248.825 bits (634), Expect = 3.844e-74
Identity = 138/361 (38.23%), Postives = 204/361 (56.51%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTELLQDGQIV--------DSPQL-----------LEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMK--ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            IW+I     YTL++GKPPFETS + DTY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P+ LP S L+  PRF ++ + L Q+G+          DSP L           L E  +              V   +  S    ++  E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  N QYI  ++ E ++TV  +P  + KKV L++  +NYM+ HL+ AG ++   E D + RLP L  +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDEN + +TYKLS +  +G  ++L S+  +  +++E  +S
Sbjct:   47 IWSIG-CIMYTLLVGKPPFETSCLKDTYIRIKKNEYTIPKHINPVAANLIQKMLRSDPATRPTISELLNDEFFTSGYIPSRLPTSCLTIAPRFSIAPSGLEQNGRKPLTALNKGPDSPALENLPEKEDVAGLRELGDAVDCHLADMLQQLTVVTSAKPSERVAVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDNLQYIEQNSTESYFTVRSYPSALNKKVTLLKYFRNYMSEHLLKAGANITPREGDELARLPYLCTWFRTRSAIVLHLSNGTVQINFFQDHTKVILCPLMAAVSYIDENRDFRTYKLSLIEEHGCCKELASRLRYARTMVEKLLS 406
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. TrEMBL
Match: A0A0X3NYQ9 (Uncharacterized protein OS=Schistocephalus solidus OX=70667 GN=TR162578 PE=4 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 6.147e-74
Identity = 140/343 (40.82%), Postives = 202/343 (58.89%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRF-----KLSKTELLQ--DGQIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYL-------MKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTV 1294
            YTL++G+PPFETS++  TY +I   SYVIP  +      +I ++L  D + RP+M  ++E  FFKGFTP CLP+S L+  PRF      L++ + L   D  +  S   L+   NL              KI   I+ P         M++SE+P   PI+WVSKWVD + +YG+ Y L D+S G +FND TRL+L  N  N QYI     E  YT+ ++P+ + KKV L++   +YM+ +L+ AG ++   E DSM RLP LR++F    AI   LSN TLQ+NF +DH K++LCP M +V  ID N + KT++ + L  NGITEDL ++  +  S+I++ V
Sbjct:   40 YTLLVGRPPFETSDLKQTYEKIKKNSYVIPPGVSVPASRLIRALLDADPSKRPSMFSMIEHEFFKGFTPNCLPVSALTTSPRFDNLCRNLAERKPLSVIDANLNMSAVHLD--ANLNCDSDDFWLGSLKKKINEVIAAPKAARNSLKAMEDSEDPASIPIYWVSKWVDYSDKYGIGYHLCDSSNGVLFNDGTRLLLTANSENLQYIEKGGTEYLYTMVEYPKSLAKKVTLLKCFTSYMHENLLNAGENITRRESDSMARLPFLRKWFRTDLAIILHLSNGTLQMNFFDDHSKIILCPLMEAVTYIDPNRDFKTFRFNLLKANGITEDLRNRLVYASSMIDSLV 380
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. TrEMBL
Match: A0A1V4KT09 (Serine/threonine-protein kinase PLK1 OS=Patagioenas fasciata monilis OX=372326 GN=PLK1 PE=4 SV=1)

HSP 1 Score: 248.44 bits (633), Expect = 4.419e-73
Identity = 138/361 (38.23%), Postives = 204/361 (56.51%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTELLQDGQIV--------DSPQL-----------LEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMK--ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            IW+I     YTL++GKPPFETS + DTY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P+ LP S L+  PRF ++ + L Q+G+          DSP L           L E  +              V   +  S    ++  E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  N QYI  ++ E ++TV  +P  + KKV L++  +NYM+ HL+ AG ++   E D + RLP L  +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDEN + +TYKLS +  +G  ++L S+  +  +++E  +S
Sbjct:  137 IWSIG-CIMYTLLVGKPPFETSCLKDTYIRIKKNEYTIPKHINPVAANLIQKMLRSDPATRPTISELLNDEFFTSGYIPSRLPTSCLTIAPRFSIAPSGLEQNGRKPLTALNKGPDSPALENLPEKEDVAGLRELGDAVDCHLADMLQQLTVVTSAKPSERVAVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDNLQYIEQNSTESYFTVRSYPSALNKKVTLLKYFRNYMSEHLLKAGANITPREGDELARLPYLCTWFRTRSAIVLHLSNGTVQINFFQDHTKVILCPLMAAVSYIDENRDFRTYKLSLIEEHGCCKELASRLRYARTMVEKLLS 496
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. TrEMBL
Match: A0A1U7RWN2 (serine/threonine-protein kinase PLK1 OS=Alligator sinensis OX=38654 GN=PLK1 PE=4 SV=1)

HSP 1 Score: 246.899 bits (629), Expect = 9.340e-73
Identity = 135/357 (37.82%), Postives = 206/357 (57.70%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTELLQDGQI--------VDSPQLL------EEYXXXXXXXXXXXXXXXXVKIISYI-----SHPYLMK--ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            IW+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ P  LP + L+ PPRF ++ T L  +G+         +DSP L       EE    +L           ++ ++ +     S   L++  E+E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  ++ E ++TV  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDE  +  TYKLS +  +G  ++L S+  +  +++E
Sbjct:  108 IWSIG-CIMYTLLVGKPPFETSCLKETYIRIKKNEYTIPKHINPVAASLIQKMLRSDPTTRPTIDELLNDEFFTSGYIPARLPTTCLTVPPRFSITPTALDANGRKPLTALNKGLDSPALEKVPEKEEEAMPRELGDAVDCHLADMLQQLTAVNAAKPSERVLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIEQNSSESYFTVRSYPSALTKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRAWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVAYIDEKRDFHTYKLSLIEEHGCCKELASRLRYARTMVE 463
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. TrEMBL
Match: K7FEE7 (Polo like kinase 1 OS=Pelodiscus sinensis OX=13735 GN=PLK1 PE=4 SV=1)

HSP 1 Score: 243.047 bits (619), Expect = 5.124e-72
Identity = 136/361 (37.67%), Postives = 204/361 (56.51%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTELLQDGQI--------VDSPQ------------LLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKE-SENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            IW+I     YTL++GKPPFETS + +TY RI    Y IP++++     +I  +L+ D  +RPT+  LL   FF  G+ PT LP + L+ PPRF ++   L   G+         +DSP             L E    +      +   LT V        P + +E +E+P   PIFWVSKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  ++ E ++TV  +P  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP LR +F   SAI   LSN T+Q+NF +DH K++LCP M +V  IDE  + +TYKLS +  +G  ++L S+  +  +++E  +S
Sbjct:   47 IWSIG-CIMYTLLVGKPPFETSCLKETYIRIKKNEYNIPKHINPVAANLIQKMLRSDPATRPTIDELLNDEFFTSGYIPTRLPTTCLTIPPRFSIAPNGLDPSGRKPLTALNKGLDSPAIERTQEKEEEAVLRELGEPVDCHLADMLQQLTIVNAAKPCERPLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLIMYNDGDSLQYIEQNSTESYFTVRSYPSTLNKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGTVQINFFQDHTKIILCPLMAAVTYIDEKRDFRTYKLSLIEEHGCCKELASRLRYARTMVEKLLS 406
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Cavefish
Match: plk1 (polo like kinase 1 [Source:NCBI gene;Acc:103034005])

HSP 1 Score: 229.565 bits (584), Expect = 2.004e-68
Identity = 127/351 (36.18%), Postives = 195/351 (55.56%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL-----------LQDGQIV-----DSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RNN 1309
            YTL++GKPPFETS + +TY RI    Y IP  ++     +I  +L  D   RP++  LL   FF  G+ P  LP S L+ PPRF ++ + L           L  G +V     D P+  + +    L Q    +     +   ++      +E+E+P   P+FW+SKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  +  E + +V  +P  + KK+ L++  +NYM+ HL+ AG ++   + D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP MG+V  I+E  E  TYK+S +   G  ++L S+  +  S++E  ++ +N 
Sbjct:  227 YTLLVGKPPFETSCLKETYVRIKKNEYSIPRQINPVAASLIRRMLHADPTLRPSVADLLTDEFFTSGYVPLRLPTSCLTVPPRFSIAPSSLDPGLLRRPLTALNTGMLVLFILVDGPEQPDSHLTDMLQQLNSVNASRPSER-DFVRQ----EEAEDPACIPVFWISKWVDYSDKYGLGYQLCDNSVGVLFNDFTRLIMYEDGDSLQYIDRNAAESYLSVRSYPPALSKKITLLKYFRNYMSEHLLKAGANITPRDGDELTRLPYLRHWFRTKSAIVLNLSNGTVQINFFQDHTKLILCPLMGAVTYINERREFCTYKMSLIEEYGCCKELASRLRYARSMVEKLMACKNT 572
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Cavefish
Match: plk1 (polo like kinase 1 [Source:NCBI gene;Acc:103034005])

HSP 1 Score: 227.639 bits (579), Expect = 1.354e-67
Identity = 128/359 (35.65%), Postives = 196/359 (54.60%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLSKTEL-----------------LQDGQIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYI--SHP-----YLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS*RNN 1309
            YTL++GKPPFETS + +TY RI    Y IP  ++     +I  +L  D   RP++  LL   FF  G+ P  LP S L+ PPRF ++ + L                 ++     D PQ  EE       +Q        ++ ++ +  S P        +E+E+P   P+FW+SKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI  +  E + +V  +P  + KK+ L++  +NYM+ HL+ AG ++   + D + RLP LR +F   SAI   LSN T+Q+NF +DH KL+LCP MG+V  I+E  E  TYK+S +   G  ++L S+  +  S++E  ++ +N 
Sbjct:  227 YTLLVGKPPFETSCLKETYVRIKKNEYSIPRQINPVAASLIRRMLHADPTLRPSVADLLTDEFFTSGYVPLRLPTSCLTVPPRFSIAPSSLDPGLLRRPLTALNTDSPIEKMGKGDQPQK-EELQQRDGPEQPDSHLTDMLQQLNSVNASRPSERDFVRQEEAEDPACIPVFWISKWVDYSDKYGLGYQLCDNSVGVLFNDFTRLIMYEDGDSLQYIDRNAAESYLSVRSYPPALSKKITLLKYFRNYMSEHLLKAGANITPRDGDELTRLPYLRHWFRTKSAIVLNLSNGTVQINFFQDHTKLILCPLMGAVTYINERREFCTYKMSLIEEYGCCKELASRLRYARSMVEKLMACKNT 584
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Cavefish
Match: plk3 (polo like kinase 3 [Source:NCBI gene;Acc:103024965])

HSP 1 Score: 98.9821 bits (245), Expect = 1.213e-21
Identity = 61/201 (30.35%), Postives = 100/201 (49.75%), Query Frame = 2 
Query:  719 SENP----KLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQ-DSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIK---TYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            S+NP    K  P  WVSKWVD +++YG  Y L++ + G +FN+ T L L        Y   +N+   +  D  PE ++++  ++     YM  +LM  GGDL   EQ       P L Q+     A+  + +N ++QVNF  DH K++L     S  ++   S  +   +Y L  L  +G + +L  + H+VV +++   S
Sbjct:  467 SKNPPCLEKPQPFLWVSKWVDYSNKYGFGYQLSNQNVGVLFNEGTHLSLCDQRRTVHYCLTNNKHFTFQADSLPEPLQRQKHIVELMAKYMEQNLM-EGGDLGFEEQPPPSASPPLLLQWIKTEHALVMLFNNGSVQVNFYADHTKVILSKSADSSYLLTYISRERVSTSYPLHVLSESGCSSELRHRLHYVVQLLQHYAS 666

HSP 2 Score: 60.8474 bits (146), Expect = 1.958e-9
Identity = 33/89 (37.08%), Postives = 54/89 (60.67%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSC 544
            +W++     YTL+ G PPFET ++ +TY+ I  + Y +P  L    +++I +VL+++ + R T+  +L   +F KGFTP  LP S  SC
Sbjct:  246 VWSLG-CVMYTLLCGNPPFETLDLKETYKCIKEVRYSLPPSLSPAAQKLISAVLQKNPSDRLTLDQILVHEYFSKGFTPDKLPPS--SC 331
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Cavefish
Match: plk2b (serine/threonine-protein kinase PLK2 [Source:NCBI gene;Acc:103027010])

HSP 1 Score: 95.9005 bits (237), Expect = 9.277e-21
Identity = 60/177 (33.90%), Postives = 94/177 (53.11%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRL-VLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVV---SEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKF 1261
            WV+KWVD +++YG  Y L+DN+ G +FN  T + +LA      Q+         YT  D PE    +V +++   +YM  +LM  GGD+V+   +E+ S+     L Q+     A+  + S+ T QVNF  DH KL+LC      ++  I+E     T+KLS+L   G + DL ++ 
Sbjct:  475 WVTKWVDYSNKYGFGYQLSDNTVGVLFNSGTHMSLLADKTTVLQHAEMGQCAVMYTT-DVPENCVGQVTILKYFAHYMEENLMD-GGDMVIDIDAEKPSIY----LLQWLKSDRALMMLFSDGTFQVNFYHDHTKLILCTQQNDYLLTYINEERVSSTFKLSALLSAGCSSDLRNRM 645

HSP 2 Score: 69.707 bits (169), Expect = 3.079e-12
Identity = 32/87 (36.78%), Postives = 50/87 (57.47%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            YT+++GKPPFET+N+ +TYR I    Y +P  +    +++I S+L R+   RP +  ++   F  +GF P  LP S     P F +S
Sbjct:  244 YTMLLGKPPFETTNLRETYRCIREARYSLPSTISLSARQLIASMLSRNPTDRPRLDEIIRHEFLTQGFMPETLPASCCLSAPDFHIS 330
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Cavefish
Match: plk2a (serine/threonine-protein kinase PLK2 [Source:NCBI gene;Acc:103036971])

HSP 1 Score: 90.8929 bits (224), Expect = 4.199e-19
Identity = 55/180 (30.56%), Postives = 94/180 (52.22%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+D++ G +FN+ T + L  +     Y     Q   +   + PE+   +V +++   +YM  +LM  GGDL      S  RL  L Q+     A+  + ++ T QVNF  DH K++LC      ++  I+E     T +LS+L   G + DL S+  + ++++
Sbjct:  477 WVTKWVDYSNKYGFGYQLSDHTVGVLFNNGTHMSLLSDKKTVHYYAELGQCMVFPTAEAPEQFVGQVTILKYFAHYMEENLMD-GGDLPNVTDVSKPRL-YLLQWLKSDRALMMLFNDGTFQVNFYHDHTKIILCNQNEEYLLTYINEERVSTTLRLSTLLRCGCSADLRSRMEYALNML 654

HSP 2 Score: 59.3066 bits (142), Expect = 5.945e-9
Identity = 30/82 (36.59%), Postives = 45/82 (54.88%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPP 550
            YT+++G+PPFET+N+ +TYR I    Y +P  L    K +I ++L +    R  +  +L   FF +GFTP  L  S     P
Sbjct:  242 YTMLLGRPPFETTNLKETYRCIREARYSMPSTLSPQAKHLISNMLAKSPEDRLRLDDVLRHDFFSQGFTPDRLSSSCCHTAP 323
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Sea Lamprey
Match: plk3 (polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:ZDB-GENE-030131-6134])

HSP 1 Score: 65.0846 bits (157), Expect = 1.383e-11
Identity = 39/138 (28.26%), Postives = 63/138 (45.65%), Query Frame = 2 
Query:  746 FWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMT---AGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVL 1150
             WV+KWVD ++  G  Y L+D S G + N+ +   L  +    Q+         + +   P  + + V  +R    +M+ HL+    A    V    D  I    L Q+     A+  + SN+T+QVNF  DH K+V+
Sbjct:  429 LWVTKWVDHSNRLGFGYKLSDGSVGVLSNEGSHFRLLSDATTVQHQAEVGTATTFDLTSPPRHMTRVVATLRYFTQFMDQHLLEGVDAVSQRVERRSDEAI---FLVQWVKTDRAVLMLFSNNTVQVNFYRDHTKVVV 563

HSP 2 Score: 52.7582 bits (125), Expect = 1.074e-7
Identity = 30/94 (31.91%), Postives = 50/94 (53.19%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFK 559
            IW++  +  +T++ G+PPF TS++ +TY  I S  +  P  L    ++++ S L  D + R ++  L    F  +GF P  LP S    PP F+
Sbjct:  208 IWSLGCAV-FTMLAGRPPFSTSDLANTYACIRSGRFNFPPSLSHAARDLLTSALTPDPDLRASLLDLQSHPFLTQGFVPDRLPTSSHLSPPIFR 300
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Sea Lamprey
Match: aurka (aurora kinase A [Source:ZFIN;Acc:ZDB-GENE-040801-161])

HSP 1 Score: 55.0694 bits (131), Expect = 9.948e-9
Identity = 22/73 (30.14%), Postives = 43/73 (58.90%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLP 526
            Y  ++G+PPFE+   N+TYRRI+ +    P +L +  K++I ++LK + ++R  +  +L+  + K      +P
Sbjct:  202 YEFLVGRPPFESETHNETYRRISKVDLRFPSHLSDGAKDLIANLLKHNPHTRLQLASVLQHPWVKANAKRIVP 274
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Sea Lamprey
Match: snrka (SNF related kinase a [Source:ZFIN;Acc:ZDB-GENE-040718-84])

HSP 1 Score: 48.9062 bits (115), Expect = 1.985e-6
Identity = 24/89 (26.97%), Postives = 46/89 (51.69%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCP 547
            IW++     Y L+ G PPF+ +N ++T   I    Y +P ++  + K++I  +L+RD   R +++ +    +  G  P+  P +  S P
Sbjct:  199 IWSLGVIL-YMLVCGHPPFQEANDSETLTMIMDCKYTVPAHISRECKDLIARMLQRDPRRRASLQEMEGHPWLCGVDPS--PAAKCSTP 284
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004519.1 (pep scaffold:Pmarinus_7.0:GL489468:5340:7079:1 gene:ENSPMAG00000004122.1 transcript:ENSPMAT00000004519.1 gene_biotype:protein_coding transcript_biotype:protein_coding)

HSP 1 Score: 44.2838 bits (103), Expect = 4.857e-6
Identity = 19/69 (27.54%), Postives = 36/69 (52.17%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTP 514
            Y L+ G PPF+ +N ++T   I    Y +P ++  +  E+I  +L+R+   R T++ +    +  G  P
Sbjct:   12 YMLVCGHPPFQEANDSETLTMIMDCKYTVPAHVSRECTELIGQMLQREPRQRATLEEIGAHPWLGGTDP 80
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Yeast
Match: CDC5 (Polo-like kinase; controls targeting and activation of Rho1p at cell division site via Rho1p guanine nucleotide exchange factors; regulates Spc72p; also functions in adaptation to DNA damage during meiosis; regulates the shape of the nucleus and expansion of the nuclear envelope during mitosis; similar to Xenopus Plx1 and S. pombe Plo1p; human homologs PLK1, PLK3 can each complement yeast cdc5 thermosensitive mutants [Source:SGD;Acc:S000004603])

HSP 1 Score: 56.225 bits (134), Expect = 5.877e-9
Identity = 44/172 (25.58%), Postives = 81/172 (47.09%), Query Frame = 2 
Query:  716 ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECF----YTVDDFPEKIKKKVKLIRNAKNYMNNHL--MTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKL 1213
            +S  PK+     V+KWVD ++++G  Y L+    G +FN+ T ++   +   F YI   ++E +    Y + + P ++ + ++++     YM  +L  ++  G     + D       LR++      + F LS+ T Q NF+ DH K+ +      V  I  + E  TY L
Sbjct:  502 KSRLPKIKHPMIVTKWVDYSNKHGFSYQLSTEDIGVLFNNGTTVLRLADAEEFWYISYDDREGWVASHYLLSEKPRELSRHLEVVDFFAKYMKANLSRVSTFGREEYHKDDVF-----LRRYTRYKPFVMFELSDGTFQFNFK-DHHKMAISDGGKLVTYISPSHESTTYPL 667

HSP 2 Score: 55.0694 bits (131), Expect = 1.451e-8
Identity = 28/95 (29.47%), Postives = 53/95 (55.79%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIP--EYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRFK 559
            IW++     Y L+IGKPPF+  ++N  Y RI    +  P  + + ++ K +I  +L  D   RP++  +++  +F+G  P  +P +++S  P F+
Sbjct:  264 IWSLGVML-YALLIGKPPFQARDVNTIYERIKCRDFSFPRDKPISDEGKILIRDILSLDPIERPSLTEIMDYVWFRGTFPPSIPSTVMSEAPNFE 357
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Nematostella
Match: EDO37827 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEP8])

HSP 1 Score: 172.17 bits (435), Expect = 2.437e-47
Identity = 77/185 (41.62%), Postives = 117/185 (63.24%), Query Frame = 2 
Query:  716 ESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFV 1270
            ++E P   P++WVSKWVD + +YGL Y L+DNS G +FND TRL+L  +  N QYI  + QE F+T+  FP+ + KKV L++  +NYM  HL+ AGG     +++S   LP LR +F     I   LSN  LQ+NF +DH K+++CP MG+V  IDEN   +T+  + +  +G +++L ++  + 
Sbjct:  401 DAEEPAATPVYWVSKWVDYSDKYGLGYTLSDNSVGVLFNDHTRLILCEDGENLQYILKNGQESFHTMKGFPDSLHKKVTLLKYFRNYMTEHLLKAGGSRGTKDEESA-HLPFLRSWFRTSKGIILHLSNGILQINFFKDHTKIIMCPRMGAVTYIDENKRFRTFPFTQIEKHGCSQELSNRLLYA 584

HSP 2 Score: 85.8853 bits (211), Expect = 7.014e-18
Identity = 44/98 (44.90%), Postives = 62/98 (63.27%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK---GFTPTCLPISILSCPPRFKL-SKTELLQDG 589
            YTL++GKPPFET ++  TY RI    Y IP  +    + +I+ +L+ D  +RPTM+ +L+  FFK   G+ PT LP+S L+ PPRF   S + LLQ G
Sbjct:  211 YTLLVGKPPFETQSLKTTYDRIKRNEYYIPSKVSHTAQLLIIKLLRPDPTTRPTMQQVLDDDFFKPSSGYMPTRLPVSCLTMPPRFATGSSSNLLQPG 308
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Nematostella
Match: EDO33652 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SRL3])

HSP 1 Score: 119.398 bits (298), Expect = 4.263e-29
Identity = 89/344 (25.87%), Postives = 159/344 (46.22%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRF--------KLSKTELLQDGQIVDSPQLL-----EEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAG--GDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            YT+++G PPFET ++ +TYRRI +  Y IP  + +    +I  +L  +  +RP +  +    FF KGF P  LP++ L   P++          SK E +   Q ++    +     EE           K       ++S           +  + A +F ++KWVD +++YG    L+D      FND +++ LA +  +  Y         ++    P  +  KV L+    NYM+ HL+  G   D++ S  DS   +P +  +F     +   LSN  +QVNF +DH K+VL P   + +   I+E+ E  +  LS L+ + ++ +++ +  +   ++ 
Sbjct:  207 YTMLVGHPPFETKSLRETYRRIRNNDYTIPSRVSDSAARLIQRMLHANPENRPKLSDIFSDDFFAKGFLPNELPLTCLCGTPKWSDYEKRSTADSKKEHVLLSQALNRKLRINADEKEEQEQKSNDMCNTKLQGVAKPLLSRDDAKNHQNNKDREEFAEVF-IAKWVDYSNKYGFGAQLSDGCVTVRFNDCSKIALASDKRSICYRDEDQPLLRFSTSYVPSNLHSKVTLLTYFANYMDKHLLKGGDPADVIPSHPDS---IPFIDIWFRTDITMVMYLSNGAMQVNFFKDHTKVVLIPGEDNALFIYINEHRESTSRLLSELNQDTVSWEVIGRLIYCKQVLR 546
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Nematostella
Match: EDO28119 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T7D2])

HSP 1 Score: 63.929 bits (154), Expect = 1.229e-12
Identity = 30/84 (35.71%), Postives = 49/84 (58.33%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRF 556
            YT+++G PPFET ++ +TYRRI +  Y IP  + +    +I  +L  +  +RP +  +    FF KGF P  LP++ L   P++
Sbjct:   32 YTMLVGHPPFETKSLRETYRRIRNNDYTIPSRVSDSAARLIQRMLHANPENRPKLSDIFSDDFFAKGFLPNELPLTCLCGTPKW 115
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Nematostella
Match: EDO35437 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SLH0])

HSP 1 Score: 50.8322 bits (120), Expect = 5.357e-7
Identity = 20/65 (30.77%), Postives = 38/65 (58.46%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFK 502
            Y  ++GKPPFE    N+TYRRI+ +    P ++    +++I  +L+ + N+R  +K +L   + +
Sbjct:  235 YEFLVGKPPFEAEGHNETYRRISRVDLRFPSHVSPGARDLISKLLQHNPNNRLPLKAVLNHPWIR 299
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Medaka
Match: PLK1 (polo like kinase 1 [Source:NCBI gene;Acc:101170155])

HSP 1 Score: 228.409 bits (581), Expect = 4.369e-68
Identity = 127/340 (37.35%), Postives = 188/340 (55.29%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS---KTELLQDGQIV----------DSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            YTL++GKPPFETS + DTY RI   +Y IP  ++     +I  +L  D   RPT+  L    FF  G+ P  LP + L+ PPRF ++     EL Q   +           + P+L+E       L+  L+   + +            +E+E+P   PIFW+SKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI     E + +V  FP  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP L  +F   SAI   LSN T+Q+NF +DH KL+LCP M +V  I+E  + +TYKLS L   G +++L S+  +   ++E
Sbjct:  227 YTLLVGKPPFETSCLKDTYNRIKKNNYTIPWQINPSASALIKRMLHADPAQRPTITDLQTDEFFTSGYVPLRLPTTCLTVPPRFSIAPSMAAELSQRRPLTAINNKGNKPNNCPKLVEAEPEECYLKDMLQQLNSIISAKPSEKAVIRQEEAEDPACIPIFWISKWVDYSDKYGLGYQLCDNSVGVLFNDFTRLIMYADGDSLQYIDKKAAESYLSVRSFPASLNKKITLLKYFRNYMSEHLLKAGANIARREGDELARLPYLCLWFRTKSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFRTYKLSLLEEFGCSKELASRMRYAKLMVE 566
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Medaka
Match: PLK1 (polo like kinase 1 [Source:NCBI gene;Acc:101170155])

HSP 1 Score: 226.868 bits (577), Expect = 1.600e-67
Identity = 128/344 (37.21%), Postives = 186/344 (54.07%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS---KTELLQDGQIV--------------DSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
            YTL++GKPPFETS + DTY RI   +Y IP  ++     +I  +L  D   RPT+  L    FF  G+ P  LP + L+ PPRF ++     EL Q   +               D P  LE       L+  L+   + +            +E+E+P   PIFW+SKWVD + +YGL Y L DNS G +FND TRL++  +  + QYI     E + +V  FP  + KK+ L++  +NYM+ HL+ AG ++   E D + RLP L  +F   SAI   LSN T+Q+NF +DH KL+LCP M +V  I+E  + +TYKLS L   G +++L S+  +   ++E
Sbjct:  227 YTLLVGKPPFETSCLKDTYNRIKKNNYTIPWQINPSASALIKRMLHADPAQRPTITDLQTDEFFTSGYVPLRLPTTCLTVPPRFSIAPSMAAELSQRRPLTAINNKAGTEKVDMKDEPAPLEAEPEECYLKDMLQQLNSIISAKPSEKAVIRQEEAEDPACIPIFWISKWVDYSDKYGLGYQLCDNSVGVLFNDFTRLIMYADGDSLQYIDKKAAESYLSVRSFPASLNKKITLLKYFRNYMSEHLLKAGANIARREGDELARLPYLCLWFRTKSAIILHLSNGTVQINFFQDHTKLILCPLMAAVTYINEKRDFRTYKLSLLEEFGCSKELASRMRYAKLMVE 570
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Medaka
Match: plk3 (polo like kinase 3 [Source:NCBI gene;Acc:101155385])

HSP 1 Score: 102.834 bits (255), Expect = 5.694e-23
Identity = 58/183 (31.69%), Postives = 96/183 (52.46%), Query Frame = 2 
Query:  746 FWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIK---TYKLSSLHGNGITEDLLSKFHFVVSIIE 1285
             WV+KWVD +++YG  Y L++ + G +FN+ T L L        Y   +N+   +  +  PE+++ + +++    NYM  +LM  GGDL   EQ S +  P L Q+     A+  + +N TLQVNF  DH K+++C       ++   S  +   TY LS L   G T +L  +  +VV +++
Sbjct:  481 LWVTKWVDYSNKYGFGYQLSNQNIGVLFNEGTHLSLCDQRQTVHYCLTNNKHFTFAANSLPEQLRSQKQIVELMANYMEQNLM-EGGDLHCEEQASALP-PLLLQWVKTDHALVMLFNNGTLQVNFYTDHTKIIVCKSSDDSYLLTYISRERVSYTYLLSMLKEMGCTSELRHRLGYVVQLLQ 661

HSP 2 Score: 65.855 bits (159), Expect = 4.114e-11
Identity = 33/88 (37.50%), Postives = 53/88 (60.23%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSC 544
            +W++     YTL+ G PPFET ++ +TY+ I  + Y +P  L    +++I  +L+++ + R T+  +L   FFKGFTP  LP S  SC
Sbjct:  245 VWSLG-CVMYTLMCGSPPFETLDLKETYKCIKEVRYNLPSSLSPAAQKLISGILQKNPSDRLTLDQILNHEFFKGFTPDKLPPS--SC 329
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Medaka
Match: plk2b (polo like kinase 2 [Source:NCBI gene;Acc:101166557])

HSP 1 Score: 99.7525 bits (247), Expect = 5.048e-22
Identity = 60/180 (33.33%), Postives = 94/180 (52.22%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+DN+ G +FN+ T + L P+     Y     Q   +   + PE    +V +++    YM  +LM  GGDL       M RL  L Q+     A+  + ++ T QVNF  DH K++LC      ++  I+E    KTYKLSSL  +G   DL  +  + ++++
Sbjct:  472 WVTKWVDYSNKYGFGYQLSDNTVGVLFNNGTHMSLLPDRKTIHYYAELGQCSVFPTCEVPEHFVGQVTVLKYFSLYMEENLMD-GGDLGTVTDTHMPRL-YLLQWLKSDRALMMLFNDGTFQVNFYHDHTKIILCCQRDEYVLTYINEERVSKTYKLSSLLTSGCPTDLHQRLLYSLNML 649

HSP 2 Score: 71.633 bits (174), Expect = 6.675e-13
Identity = 35/96 (36.46%), Postives = 55/96 (57.29%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            IW +     YT+++G+PPFET+N+ +TY+ I    Y +P  L    K++I S+L +    RP +  +L   FF +GF+P  LP+S     P F +S
Sbjct:  232 IWALG-CVMYTMLLGRPPFETTNLKETYKCIREARYSLPSSLSPQAKQLISSLLAKIPEDRPNLDHILRHDFFTQGFSPERLPVSCCHSAPDFHIS 326
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Medaka
Match: plk2b (polo like kinase 2 [Source:NCBI gene;Acc:101166557])

HSP 1 Score: 99.7525 bits (247), Expect = 5.761e-22
Identity = 60/180 (33.33%), Postives = 94/180 (52.22%), Query Frame = 2 
Query:  749 WVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMI--IDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSII 1282
            WV+KWVD +++YG  Y L+DN+ G +FN+ T + L P+     Y     Q   +   + PE    +V +++    YM  +LM  GGDL       M RL  L Q+     A+  + ++ T QVNF  DH K++LC      ++  I+E    KTYKLSSL  +G   DL  +  + ++++
Sbjct:  440 WVTKWVDYSNKYGFGYQLSDNTVGVLFNNGTHMSLLPDRKTIHYYAELGQCSVFPTCEVPEHFVGQVTVLKYFSLYMEENLMD-GGDLGTVTDTHMPRL-YLLQWLKSDRALMMLFNDGTFQVNFYHDHTKIILCCQRDEYVLTYINEERVSKTYKLSSLLTSGCPTDLHQRLLYSLNML 617

HSP 2 Score: 71.633 bits (174), Expect = 6.113e-13
Identity = 35/96 (36.46%), Postives = 55/96 (57.29%), Query Frame = 2 
Query:  281 IWNIKFSYRYTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFF-KGFTPTCLPISILSCPPRFKLS 565
            IW +     YT+++G+PPFET+N+ +TY+ I    Y +P  L    K++I S+L +    RP +  +L   FF +GF+P  LP+S     P F +S
Sbjct:  232 IWALG-CVMYTMLLGRPPFETTNLKETYKCIREARYSLPSSLSPQAKQLISSLLAKIPEDRPNLDHILRHDFFTQGFSPERLPVSCCHSAPDFHIS 326
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Planmine SMEST
Match: SMESG000007751.1 (SMESG000007751.1)

HSP 1 Score: 640.188 bits (1650), Expect = 0.000e+0
Identity = 329/330 (99.70%), Postives = 329/330 (99.70%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRFKLSKTELLQDGQIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRFKLSKTELLQDGQIVDSPQLLEEYTNLKLLQQQLKDTLTNVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLH NGITEDLLSKFHFVVSIIETTVS
Sbjct:  207 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRFKLSKTELLQDGQIVDSPQLLEEYTNLKLLQQQLKDTLTNVKIISYISHPYLMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHDNGITEDLLSKFHFVVSIIETTVS 536
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Planmine SMEST
Match: SMESG000022441.1 (SMESG000022441.1)

HSP 1 Score: 250.366 bits (638), Expect = 1.409e-76
Identity = 140/359 (39.00%), Postives = 206/359 (57.38%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRFK--------------------LSKTELLQDG--QIVDSPQLLEEYXXXXXXXXXXXXXXXXV--KIISYISHPY-----LMKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFMEPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSSLHGNGITEDLLSKFHFVVSIIETTVS 1297
            YTL+IGKPPFET  + DTY +I    Y IP  L +  +EII ++L  D   RP+M  LLEM F+KGF P+ LP S+++  PRF                     +S   +   G  +I+  P   E Y N  ++    +     V  KII+   +P      LM+ESE P LAP++WV+KWVD +  YGL Y L+D S G +FND +R++L  N  N QYI  +  E  YT+  +P+K+KKKV L++  + YM  +LMTAG ++  ++++SMIRLP ++ +F   SAI   LSN T+Q+N   DH KL++CP +G+V  ID   + +T+KL SL   G+T ++  +  + + +IE   S
Sbjct:  205 YTLLIGKPPFETETLRDTYTKIKKNEYSIPFNLCDSTQEIIRALLDSDAMKRPSMNKLLEMEFYKGFIPSGLPTSVMTTVPRFDNIQIKNKPLSSIGNTISVPIISGIGVTGTGHSEILPGPSGDENYNNRYIVDLIRQIKNVIVDMKIINSADYPSKKMLDLMEESEEPNLAPVYWVAKWVDYSDRYGLGYQLSDGSNGVVFNDISRIILTANCQNLQYIEKNGTEFLYTITSYPDKLKKKVTLLQYFQTYMIENLMTAGENM-FNDKESMIRLPYVKAWFRTKSAIVLYLSNGTVQINLFGDHTKLIVCPLVGAVTYIDGTKDFRTFKLESLRHKGMTNEMHQRLQYTLRMIERISS 562
[Close]
BLAST of Serine/threonine-protein kinase PLK vs. Planmine SMEST
Match: SMESG000017012.1 (SMESG000017012.1)

HSP 1 Score: 109.768 bits (273), Expect = 2.590e-26
Identity = 80/253 (31.62%), Postives = 121/253 (47.83%), Query Frame = 2 
Query:  308 YTLIIGKPPFETSNINDTYRRITSISYVIPEYLDEDVKEIILSVLKRDVNSRPTMKMLLEMSFFKGFTPTCLPISILSCPPRFK------------LSKT---------ELLQDGQIVDSPQLLEEYXXXXXXXXXXXXXXXXVKIISYISHPYL--MKESENPKLAPIFWVSKWVDITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVDDFPEKIKKKVKLIRNAKNYMNNHLMT 997
            Y L+ G  PF   N  + +    S SY +P+ L    KEII  +L++  + R +    LE+ +F  F P  LP S+LS PPRF             L+KT          LL   + VD     E    L      L ++   ++         L  M +S++P L PI+W+SKWVD  + +GL Y L D STG  F + T +V+  N  N Q+I     E  +T ++ PEK+ K+ ++++  +NYM  +L T
Sbjct:   85 YNLLFGTHPF--PNNGNEFFTCYSFSYTLPKDLTPSTKEIIHLLLEKIPSKRISASDALELDYFTEFIPDSLPTSVLSMPPRFDGLVNKDKSIAEDLTKTIYYNPSPFSHLLNSVEDVDEIYRNEHLKALADQLHSLLESSPVLESTETEKSKLLDLMSDSKDPSLEPIYWISKWVDFANAFGLGYKLTDASTGVFFTNKTCMVMTENQQNIQFIDDEKTEYLFTNENLPEKLFKRREILKYVENYMQINLAT 335
The following BLAST results are available for this feature:
BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLK12.773e-7136.64polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:90... [more]
PLK33.096e-2132.56polo like kinase 3 [Source:HGNC Symbol;Acc:HGNC:21... [more]
PLK24.264e-1928.96polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19... [more]
PLK24.381e-1928.96polo like kinase 2 [Source:HGNC Symbol;Acc:HGNC:19... [more]
PLK14.472e-1742.86polo like kinase 1 [Source:HGNC Symbol;Acc:HGNC:90... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plk-11.028e-5633.15Serine/threonine-protein kinase plk-1 [Source:Uni... [more]
plk-11.065e-5633.15Serine/threonine-protein kinase plk-1 [Source:Uni... [more]
plk-23.713e-4440.10Serine/threonine-protein kinase plk-2 [Source:Uni... [more]
plk-32.756e-3034.34Serine/threonine-protein kinase plk-3 [Source:Uni... [more]
plk-32.756e-3034.34Serine/threonine-protein kinase plk-3 [Source:Uni... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99)
Total hits: 2
Match NameE-valueIdentityDescription
polo4.911e-5733.61gene:FBgn0003124 transcript:FBtr0074839[more]
polo4.911e-5733.61gene:FBgn0003124 transcript:FBtr0100318[more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plk11.272e-6834.70polo-like kinase 1 (Drosophila) [Source:ZFIN;Acc:Z... [more]
plk11.272e-6834.70polo-like kinase 1 (Drosophila) [Source:ZFIN;Acc:Z... [more]
plk34.741e-2332.14polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:Z... [more]
plk2b1.107e-2232.22polo-like kinase 2b (Drosophila) [Source:ZFIN;Acc:... [more]
plk2b1.107e-2232.22polo-like kinase 2b (Drosophila) [Source:ZFIN;Acc:... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plk17.634e-7338.44polo like kinase 1 [Source:NCBI gene;Acc:407937][more]
plk12.298e-7036.21polo like kinase 1 [Source:NCBI gene;Acc:407937][more]
plk12.366e-7036.21polo like kinase 1 [Source:NCBI gene;Acc:407937][more]
plk31.974e-3829.59polo-like kinase 3 [Source:NCBI gene;Acc:448451][more]
plk26.303e-2724.24polo-like kinase 2 [Source:NCBI gene;Acc:100125189... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99)
Total hits: 5
Match NameE-valueIdentityDescription
Plk11.213e-7136.91polo like kinase 1 [Source:MGI Symbol;Acc:MGI:9762... [more]
Plk32.777e-2131.98polo like kinase 3 [Source:MGI Symbol;Acc:MGI:1096... [more]
Plk32.821e-2131.98polo like kinase 3 [Source:MGI Symbol;Acc:MGI:1096... [more]
Plk28.322e-1928.96polo like kinase 2 [Source:MGI Symbol;Acc:MGI:1099... [more]
Plk54.229e-1328.06polo like kinase 5 [Source:MGI Symbol;Acc:MGI:3026... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt)
Total hits: 5
Match NameE-valueIdentityDescription
sp|Q62673|PLK1_RAT7.718e-7136.91Serine/threonine-protein kinase PLK1 OS=Rattus nor... [more]
sp|Q07832|PLK1_MOUSE8.482e-7136.91Serine/threonine-protein kinase PLK1 OS=Mus muscul... [more]
sp|Q2TA25|PLK1_BOVIN1.035e-7036.64Serine/threonine-protein kinase PLK1 OS=Bos taurus... [more]
sp|P53350|PLK1_HUMAN1.332e-7036.64Serine/threonine-protein kinase PLK1 OS=Homo sapie... [more]
sp|P70032|PLK1_XENLA2.249e-7036.77Serine/threonine-protein kinase PLK1 OS=Xenopus la... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL)
Total hits: 5
Match NameE-valueIdentityDescription
A0A2I0LX113.844e-7438.23Polo-like kinase 1 OS=Columba livia OX=8932 GN=PLK... [more]
A0A0X3NYQ96.147e-7440.82Uncharacterized protein OS=Schistocephalus solidus... [more]
A0A1V4KT094.419e-7338.23Serine/threonine-protein kinase PLK1 OS=Patagioena... [more]
A0A1U7RWN29.340e-7337.82serine/threonine-protein kinase PLK1 OS=Alligator ... [more]
K7FEE75.124e-7237.67Polo like kinase 1 OS=Pelodiscus sinensis OX=13735... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99)
Total hits: 5
Match NameE-valueIdentityDescription
plk12.004e-6836.18polo like kinase 1 [Source:NCBI gene;Acc:103034005... [more]
plk11.354e-6735.65polo like kinase 1 [Source:NCBI gene;Acc:103034005... [more]
plk31.213e-2130.35polo like kinase 3 [Source:NCBI gene;Acc:103024965... [more]
plk2b9.277e-2133.90serine/threonine-protein kinase PLK2 [Source:NCBI ... [more]
plk2a4.199e-1930.56serine/threonine-protein kinase PLK2 [Source:NCBI ... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99)
Total hits: 4
Match NameE-valueIdentityDescription
plk31.383e-1128.26polo-like kinase 3 (Drosophila) [Source:ZFIN;Acc:Z... [more]
aurka9.948e-930.14aurora kinase A [Source:ZFIN;Acc:ZDB-GENE-040801-1... [more]
snrka1.985e-626.97SNF related kinase a [Source:ZFIN;Acc:ZDB-GENE-040... [more]
ENSPMAT00000004519.14.857e-627.54pep scaffold:Pmarinus_7.0:GL489468:5340:7079:1 gen... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46)
Total hits: 1
Match NameE-valueIdentityDescription
CDC55.877e-925.58Polo-like kinase; controls targeting and activatio... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46)
Total hits: 4
Match NameE-valueIdentityDescription
EDO378272.437e-4741.62Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO336524.263e-2925.87Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO281191.229e-1235.71Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
EDO354375.357e-730.77Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99)
Total hits: 5
Match NameE-valueIdentityDescription
PLK14.369e-6837.35polo like kinase 1 [Source:NCBI gene;Acc:101170155... [more]
PLK11.600e-6737.21polo like kinase 1 [Source:NCBI gene;Acc:101170155... [more]
plk35.694e-2331.69polo like kinase 3 [Source:NCBI gene;Acc:101155385... [more]
plk2b5.048e-2233.33polo like kinase 2 [Source:NCBI gene;Acc:101166557... [more]
plk2b5.761e-2233.33polo like kinase 2 [Source:NCBI gene;Acc:101166557... [more]
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BLAST of Serine/threonine-protein kinase PLK vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST)
Total hits: 3
Match NameE-valueIdentityDescription
SMESG000007751.10.000e+099.70SMESG000007751.1[more]
SMESG000022441.11.409e-7639.00SMESG000022441.1[more]
SMESG000017012.12.590e-2631.62SMESG000017012.1[more]
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Sequences
The following sequences are available for this feature:

transcript sequence

>SMED30034742 ID=SMED30034742|Name=Serine/threonine-protein kinase PLK|organism=Schmidtea mediterranea sexual|type=transcript|length=1388bp
ATCTTATAAATGTAATTATAATAATTATATAATATTATTATAACTCCAGA
TCTTTAATGCTTATTCGGAAAAATAGCACTTTATTTTACTCGTGCTACCG
TTTCTGTTTTCGGTTATCAGTAAAAAAAACAGTTTATTGCTTTAACTTGA
CAATTCTTACAATAAATTGCTTGAAAACAATTTTTTGAACGTTTGATGAG
TAACAGTATTCAATTTCAACTAGGATCCATTATTTTTACGAATCTTAATG
TTTTACACTTAACGTTTGTCTATCATATTGATTTGGAATATTAAATTTTC
TTACAGATATACCTTAATCATTGGTAAACCTCCATTTGAAACTTCTAATA
TCAATGATACTTACAGACGAATAACGTCGATTTCTTATGTAATTCCTGAA
TATTTGGATGAGGACGTGAAGGAAATAATACTTTCTGTATTGAAAAGAGA
TGTTAATAGCCGTCCTACTATGAAAATGTTGTTAGAAATGAGTTTTTTTA
AAGGTTTTACTCCAACCTGTCTACCAATCAGTATTTTATCGTGTCCTCCT
CGCTTTAAATTATCCAAAACTGAATTATTGCAAGACGGTCAGATAGTTGA
TTCTCCTCAATTACTGGAAGAATATACGAATTTAAAGCTATTACAGCAAC
AGCTAAAGGACACTTTGACCAATGTCAAAATCATTTCATATATTTCCCAT
CCGTATTTAATGAAAGAAAGCGAAAATCCTAAATTAGCTCCCATTTTTTG
GGTGTCAAAGTGGGTCGATATCACGTCTGAATATGGGCTTTTCTACATGT
TAAACGACAACTCAACTGGGTCTATATTCAACGATGACACTCGACTGGTG
CTTGCACCGAATGATTTCAATTTCCAATATATCGGTTGCTCAAATCAAGA
ATGTTTCTATACGGTAGATGATTTTCCGGAAAAAATTAAAAAGAAAGTCA
AGCTGATAAGAAACGCAAAGAATTACATGAATAACCATCTGATGACAGCT
GGTGGGGATTTAGTAGTATCAGAACAGGATTCCATGATTAGACTTCCGAA
TCTTCGACAGTTTTTCATGGAACCGAGTGCCATTTGTTTTATGTTGAGCA
ATGACACACTTCAGGTTAACTTTCAAGAAGATCATGTCAAACTTGTTTTA
TGTCCGTTCATGGGTTCTGTGATGATTATTGATGAAAATAGTGAAATTAA
AACCTACAAATTATCCAGCCTGCATGGCAATGGAATCACTGAAGATTTAT
TATCCAAATTTCATTTTGTTGTCTCTATTATTGAAACAACTGTTTCCTAA
AGAAATAATAAATATTTTATTATTGCAATTTTTCATTTCTTACAAACGAT
TTCGTAATATAGCGTTTTTGTAGGGTTTTGAATTGTCA
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protein sequence of SMED30034742-orf-1

>SMED30034742-orf-1 ID=SMED30034742-orf-1|Name=SMED30034742-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=277bp
MKMLLEMSFFKGFTPTCLPISILSCPPRFKLSKTELLQDGQIVDSPQLLE
EYTNLKLLQQQLKDTLTNVKIISYISHPYLMKESENPKLAPIFWVSKWVD
ITSEYGLFYMLNDNSTGSIFNDDTRLVLAPNDFNFQYIGCSNQECFYTVD
DFPEKIKKKVKLIRNAKNYMNNHLMTAGGDLVVSEQDSMIRLPNLRQFFM
EPSAICFMLSNDTLQVNFQEDHVKLVLCPFMGSVMIIDENSEIKTYKLSS
LHGNGITEDLLSKFHFVVSIIETTVS*
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Annotated Terms
The following terms have been associated with this transcript:
Vocabulary: Planarian Anatomy
TermDefinition
PLANA:0000136whole organism
PLANA:0002089reproductive organ
PLANA:0002109X1 cell
Vocabulary: INTERPRO
TermDefinition
IPR036947POLO_box_dom_sf
IPR033695POLO_box_2
IPR033701POLO_box_1
IPR000959POLO_box_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom_sf
Vocabulary: molecular function
TermDefinition
GO:0005515protein binding
GO:0005524ATP binding
GO:0004672protein kinase activity
GO:0000166nucleotide binding
GO:0004674protein serine/threonine kinase activity
GO:0016301kinase activity
GO:0016740transferase activity
Vocabulary: biological process
TermDefinition
GO:0006468protein phosphorylation
GO:0016310phosphorylation
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR036947POLO box domain superfamilyGENE3DG3DSA:3.30.1120.30coord: 96..192
e-value: 5.2E-64
score: 217.4
IPR036947POLO box domain superfamilyGENE3DG3DSA:3.30.1120.30coord: 79..272
e-value: 5.2E-64
score: 217.4
IPR000959POLO box domainPFAMPF00659POLO_boxcoord: 102..163
e-value: 2.1E-14
score: 53.5
coord: 203..264
e-value: 3.2E-13
score: 49.6
IPR000959POLO box domainPROSITEPS50078POLO_BOXcoord: 101..164
score: 15.207
IPR000959POLO box domainPROSITEPS50078POLO_BOXcoord: 199..268
score: 15.542
NoneNo IPR availablePANTHERPTHR24345SERINE/THREONINE-PROTEIN KINASE PLKcoord: 85..275
NoneNo IPR availablePANTHERPTHR24345:SF52SERINE/THREONINE-PROTEIN KINASE PLK-1coord: 85..275
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..25
score: 5.0
NoneNo IPR availableSUPERFAMILYSSF82615Polo-box domaincoord: 186..273
NoneNo IPR availableSUPERFAMILYSSF82615Polo-box domaincoord: 56..178
IPR033695Second polo-box domainCDDcd13117POLO_box_2coord: 195..272
e-value: 2.00927E-20
score: 81.0892
IPR033701First polo-box domainCDDcd13118POLO_box_1coord: 91..179
e-value: 2.71724E-30
score: 107.407