cAMP-dependent protein kinase catalytic subunit
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034681 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 11
Homology
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 514.227 bits (1323), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T LD+FE +KTLGTGSFGRV+L HK++ ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 514.227 bits (1323), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T LD+FE +KTLGTGSFGRV+L HK++ ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACB (protein kinase cAMP-activated catalytic subunit beta [Source:HGNC Symbol;Acc:HGNC:9381]) HSP 1 Score: 510.76 bits (1314), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ + S VK FL +AK++F K+++P Q L++FE KTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+Y+FKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIK H WF + DW + +++++ APFIPK RG GDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNAATAKKGSEVES-VKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 508.064 bits (1307), Expect = 2.939e-180 Identity = 239/340 (70.29%), Postives = 300/340 (88.24%), Query Frame = 2
Query: 152 DNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
++S VK FL +AK++F K++ P Q T LD+FE +KTLGTGSFGRV+L HK++ ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 4 NSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Match: PRKACA (protein kinase cAMP-activated catalytic subunit alpha [Source:HGNC Symbol;Acc:HGNC:9380]) HSP 1 Score: 508.064 bits (1307), Expect = 2.939e-180 Identity = 239/340 (70.29%), Postives = 300/340 (88.24%), Query Frame = 2
Query: 152 DNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
++S VK FL +AK++F K++ P Q T LD+FE +KTLGTGSFGRV+L HK++ ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 4 NSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 526.554 bits (1355), Expect = 0.000e+0 Identity = 248/344 (72.09%), Postives = 306/344 (88.95%), Query Frame = 2
Query: 140 RDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+D K+++ +K FL++A+++F ++++P Q T LD+F+ +KTLGTGSFGRV+L HK+S Y+A+K+LDK K+VKLKQVEHTLNEKRILQAIDFPFL+ + +SFKDNSNLYMVLEF++GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID+ GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+KFPSHFS ELKDLL+N+LQ DLT+R+GN++NG +DIKNH WF S DW + ++K++ APF+PKCRGPGD SNFD+YEEE L+IS T KC EF EF
Sbjct: 16 KDNKNSASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 359
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 522.702 bits (1345), Expect = 0.000e+0 Identity = 247/336 (73.51%), Postives = 300/336 (89.29%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
VK FL++A+++F ++++P Q T LD+F+ +KTLGTGSFGRV+L HK+S Y+A+K+LDK K+VKLKQVEHTLNEKRILQAIDFPFL+ + +SFKDNSNLYMVLEF++GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID+ GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+KFPSHFS ELKDLL+N+LQ DLT+R+GN++NG +DIKNH WF S DW + ++K++ APF+PKCRGPGD SNFD+YEEE L+IS T KC EF EF
Sbjct: 35 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 370
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0 Identity = 246/336 (73.21%), Postives = 300/336 (89.29%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+K FL++A+++F ++++P Q T LD+F+ +KTLGTGSFGRV+L HK+S Y+A+K+LDK K+VKLKQVEHTLNEKRILQAIDFPFL+ + +SFKDNSNLYMVLEF++GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID+ GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+KFPSHFS ELKDLL+N+LQ DLT+R+GN++NG +DIKNH WF S DW + ++K++ APF+PKCRGPGD SNFD+YEEE L+IS T KC EF EF
Sbjct: 46 IKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 381
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 521.931 bits (1343), Expect = 0.000e+0 Identity = 247/336 (73.51%), Postives = 300/336 (89.29%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
VK FL++A+++F ++++P Q T LD+F+ +KTLGTGSFGRV+L HK+S Y+A+K+LDK K+VKLKQVEHTLNEKRILQAIDFPFL+ + +SFKDNSNLYMVLEF++GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID+ GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+KFPSHFS ELKDLL+N+LQ DLT+R+GN++NG +DIKNH WF S DW + ++K++ APF+PKCRGPGD SNFD+YEEE L+IS T KC EF EF
Sbjct: 8 VKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Match: kin-1 (cAMP-dependent protein kinase catalytic subunit [Source:UniProtKB/Swiss-Prot;Acc:P21137]) HSP 1 Score: 521.161 bits (1341), Expect = 0.000e+0 Identity = 246/337 (73.00%), Postives = 300/337 (89.02%), Query Frame = 2
Query: 161 YVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+ K FL++A+++F ++++P Q T LD+F+ +KTLGTGSFGRV+L HK+S Y+A+K+LDK K+VKLKQVEHTLNEKRILQAIDFPFL+ + +SFKDNSNLYMVLEF++GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID+ GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+KFPSHFS ELKDLL+N+LQ DLT+R+GN++NG +DIKNH WF S DW + ++K++ APF+PKCRGPGD SNFD+YEEE L+IS T KC EF EF
Sbjct: 13 FFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKIEAPFLPKCRGPGDASNFDDYEEEPLRISGTEKCAKEFAEF 349
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0335495) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 249/353 (70.54%), Postives = 301/353 (85.27%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNS-YVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T + D + VK FLE+AK+ F DK+ T LD+FE +KTLGTGSFGRV++ HK +K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL+ L Y FKDNSNLYMVLE+V GGEMFSHLR+VG+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GYLK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHF +LKDLLRN+LQ DLT+R+GN++ G +DIKN WF S DW + F+K++ APFIP+C+GPGDTSNFD+YEEE L+IS+T KC EF EF
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079852) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 249/353 (70.54%), Postives = 301/353 (85.27%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNS-YVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T + D + VK FLE+AK+ F DK+ T LD+FE +KTLGTGSFGRV++ HK +K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL+ L Y FKDNSNLYMVLE+V GGEMFSHLR+VG+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GYLK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHF +LKDLLRN+LQ DLT+R+GN++ G +DIKN WF S DW + F+K++ APFIP+C+GPGDTSNFD+YEEE L+IS+T KC EF EF
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C1 (gene:FBgn0000273 transcript:FBtr0079851) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 249/353 (70.54%), Postives = 301/353 (85.27%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNS-YVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T + D + VK FLE+AK+ F DK+ T LD+FE +KTLGTGSFGRV++ HK +K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL+ L Y FKDNSNLYMVLE+V GGEMFSHLR+VG+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GYLK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHF +LKDLLRN+LQ DLT+R+GN++ G +DIKN WF S DW + F+K++ APFIP+C+GPGDTSNFD+YEEE L+IS+T KC EF EF
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075529) HSP 1 Score: 356.295 bits (913), Expect = 1.402e-118 Identity = 162/296 (54.73%), Postives = 224/296 (75.68%), Query Frame = 2
Query: 233 YKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEE 1120
Y LD+++I+KT+GTG+FGRV L + S+KY A+K+L ++++LKQ+EH NE+ IL+ I PF+I L++S KD+SNLYM+ ++V GGE+F++LR GKF+ + FYA+++V A EYLH L ++YRDLKPEN+LI+ G+LKITDFGFAK+++ RTWTLCGTPEY+APEII SKG+N AVDWWALG+LI+EM GYPPF+ +QP IYEKI++ KI++ H P KDL++ +L D T+R GNM+NGA D+K H WF +W + K+L P +P GDT NFD+Y E+
Sbjct: 186 YHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEK 481
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Match: Pka-C3 (gene:FBgn0000489 transcript:FBtr0075528) HSP 1 Score: 355.91 bits (912), Expect = 2.066e-117 Identity = 162/296 (54.73%), Postives = 224/296 (75.68%), Query Frame = 2
Query: 233 YKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEE 1120
Y LD+++I+KT+GTG+FGRV L + S+KY A+K+L ++++LKQ+EH NE+ IL+ I PF+I L++S KD+SNLYM+ ++V GGE+F++LR GKF+ + FYA+++V A EYLH L ++YRDLKPEN+LI+ G+LKITDFGFAK+++ RTWTLCGTPEY+APEII SKG+N AVDWWALG+LI+EM GYPPF+ +QP IYEKI++ KI++ H P KDL++ +L D T+R GNM+NGA D+K H WF +W + K+L P +P GDT NFD+Y E+
Sbjct: 269 YHLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREIRHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLHSLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKAVDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRTKRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEK 564
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacbb (protein kinase, cAMP-dependent, catalytic, beta b [Source:ZFIN;Acc:ZDB-GENE-050904-4]) HSP 1 Score: 523.857 bits (1348), Expect = 0.000e+0 Identity = 250/352 (71.02%), Postives = 305/352 (86.65%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ + S VK FL +AK++F K++ P+Q T LD+F+ KTLGTGSFGRV+L HK S +Y+A+KVLDK K+VKLKQVEHTLNEKRILQA+ FPFL++L+Y+FKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN+RNG +DIKNH WF + DW + +++++ APFIPKCRGPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNAATAKKGNELES-VKEFLAKAKEDFLRKWESPQQSTTCLDDFDRQKTLGTGSFGRVLLVKHKASDQYYAMKVLDKQKVVKLKQVEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacaa (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a [Source:ZFIN;Acc:ZDB-GENE-050114-6]) HSP 1 Score: 521.546 bits (1342), Expect = 0.000e+0 Identity = 245/352 (69.60%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN PT K + VK FL +AK++F K+++P Q T LD FE LKTLGTGSFGRV+L HK+S ++ A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L++SFKDN+NLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW + ++K++ APFIPKC+GPGDTSNFD+Y+EE +++S T KC EF EF
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDHFERLKTLGTGSFGRVMLVKHKESGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNTNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKGHKWFATTDWIAIYQKKVEAPFIPKCKGPGDTSNFDDYDEEEIRVSITEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacab (protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b [Source:ZFIN;Acc:ZDB-GENE-040801-208]) HSP 1 Score: 518.85 bits (1335), Expect = 0.000e+0 Identity = 241/352 (68.47%), Postives = 306/352 (86.93%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGNTP KR + S VK FL AK++F K+++P Q T L++F+ LKTLGTGSFGRV+L H+++ +++A+K+L+K K+VKLKQ+EHTLNEKRILQA+ FPFL++L+YSFKDN+NLYMV+++V GGEMFSHLRR+G+FSE HA+FYASQ+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIK H WF + DW + +++ + APF+PKCRGPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNTPAAKRGNEMES-VKEFLAFAKEDFLRKWENPAQNTACLEDFDRLKTLGTGSFGRVMLVRHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNTNLYMVMQYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLMYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFVPKCRGPGDTSNFDDYEEEEIRVSFTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 499.975 bits (1286), Expect = 1.747e-176 Identity = 233/339 (68.73%), Postives = 301/339 (88.79%), Query Frame = 2
Query: 155 NSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
++ +K L +AK++F +K++ ++ T LD+F+ LKTLGTGSFGRV+L HK+S++Y A+K+LDKLK+VKLKQ+EHTLNEK+ILQA+ FPFL+KL+ +FKDNSNLYMV+ ++ GGEMFSHLRR+G+FSE +A+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+++PSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIKNH WF S DW + ++K++ AP IPKCRGPGDTSNFD Y+EEV+++S + +C+ EF++F
Sbjct: 57 DTAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Match: prkacba (protein kinase, cAMP-dependent, catalytic, beta a [Source:ZFIN;Acc:ZDB-GENE-040426-1351]) HSP 1 Score: 499.975 bits (1286), Expect = 1.747e-176 Identity = 233/339 (68.73%), Postives = 301/339 (88.79%), Query Frame = 2
Query: 155 NSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
++ +K L +AK++F +K++ ++ T LD+F+ LKTLGTGSFGRV+L HK+S++Y A+K+LDKLK+VKLKQ+EHTLNEK+ILQA+ FPFL+KL+ +FKDNSNLYMV+ ++ GGEMFSHLRR+G+FSE +A+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K+++PSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIKNH WF S DW + ++K++ AP IPKCRGPGDTSNFD Y+EEV+++S + +C+ EF++F
Sbjct: 57 DTAMKETLAKAKEDFLNKWECQQKSTACLDDFDKLKTLGTGSFGRVMLVKHKQSEQYFAMKILDKLKVVKLKQIEHTLNEKKILQAVSFPFLVKLECAFKDNSNLYMVMRYIQGGEMFSHLRRIGRFSEQNARFYAAQIVLTFEYLHMLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRYPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKNHRWFASTDWIAIYEKKVDAPIIPKCRGPGDTSNFDEYDEEVIRVSVSEQCSKEFLDF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: prkacb (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:100038053]) HSP 1 Score: 523.472 bits (1347), Expect = 0.000e+0 Identity = 246/352 (69.89%), Postives = 308/352 (87.50%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ + S VK FL +AK++F K++ P Q T LD+FE +KTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIKNH WF + DW + +++++ APFIPKCRGPGDTSNFD+YEEE +++S T KC EF +F
Sbjct: 1 MGNAATAKKGNEIES-VKEFLAKAKEDFLRKWETPPQNTASLDDFERIKTLGTGSFGRVMLVKHKGAEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSLTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 245/352 (69.60%), Postives = 306/352 (86.93%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ + S VK FL +AK++F K+++P Q T L++FE +KTLGTGSFGRV+L HK++ + A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYASQ+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW + ++K++ APFIPKC+GPGDTSNFD+YEEE +++S T KC EF +F
Sbjct: 1 MGNAATAKKGGEIES-VKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 516.924 bits (1330), Expect = 0.000e+0 Identity = 244/358 (68.16%), Postives = 307/358 (85.75%), Query Frame = 2
Query: 98 ISVYPLMGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
++ L + P + R E YVK FL +AK++F K+++P Q T L++FE +KTLGTGSFGRV+L HK++ + A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYASQ+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW + ++K++ APFIPKC+GPGDTSNFD+YEEE +++S T KC EF +F
Sbjct: 12 LATSQLSPSPPNLDR-EGQERYVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 368
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 512.686 bits (1319), Expect = 0.000e+0 Identity = 239/337 (70.92%), Postives = 299/337 (88.72%), Query Frame = 2
Query: 161 YVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+VK FL +AK++F K+++P Q T L++FE +KTLGTGSFGRV+L HK++ + A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYASQ+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW + ++K++ APFIPKC+GPGDTSNFD+YEEE +++S T KC EF +F
Sbjct: 1 FVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 337
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Match: ints8 (integrator complex subunit 8 [Source:Xenbase;Acc:XB-GENE-980129]) HSP 1 Score: 512.301 bits (1318), Expect = 0.000e+0 Identity = 240/338 (71.01%), Postives = 299/338 (88.46%), Query Frame = 2
Query: 158 SYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
S VK FL +AK++F K+++P Q T L++FE +KTLGTGSFGRV+L HK++ + A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYASQ+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW + ++K++ APFIPKC+GPGDTSNFD+YEEE +++S T KC EF +F
Sbjct: 31 STVKEFLAKAKEDFLKKWENPAQNTAHLEQFERIKTLGTGSFGRVMLVRHKENGSHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVTDIKGHKWFSTTDWIAVYQKKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSITEKCAKEFSDF 368
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 516.153 bits (1328), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 305/352 (86.65%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T +LD+F+ +KTLGTGSFGRV+L HK+S ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkaca (protein kinase, cAMP dependent, catalytic, alpha [Source:MGI Symbol;Acc:MGI:97592]) HSP 1 Score: 509.605 bits (1311), Expect = 0.000e+0 Identity = 238/336 (70.83%), Postives = 298/336 (88.69%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
VK FL +AK++F K++ P Q T +LD+F+ +KTLGTGSFGRV+L HK+S ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 8 VKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 343
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 508.834 bits (1309), Expect = 1.526e-180 Identity = 243/352 (69.03%), Postives = 303/352 (86.08%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGNT K+ + S VK FL +AK++F K+++P L++FE KTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIK H WF + DW + +++++ APFIPK RG GDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNTAIAKKGSEVES-VKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 501.516 bits (1290), Expect = 8.482e-178 Identity = 237/336 (70.54%), Postives = 295/336 (87.80%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
VK FL +AK++F K+++P L++FE KTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIK H WF + DW + +++++ APFIPK RG GDTSNFD+YEEE +++S T KC EF EF
Sbjct: 3 VKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 338
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Match: Prkacb (protein kinase, cAMP dependent, catalytic, beta [Source:MGI Symbol;Acc:MGI:97594]) HSP 1 Score: 499.975 bits (1286), Expect = 3.126e-177 Identity = 236/336 (70.24%), Postives = 295/336 (87.80%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+K FL +AK++F K+++P L++FE KTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIK H WF + DW + +++++ APFIPK RG GDTSNFD+YEEE +++S T KC EF EF
Sbjct: 4 LKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 339
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P12370|KAPC1_DROME (cAMP-dependent protein kinase catalytic subunit 1 OS=Drosophila melanogaster OX=7227 GN=Pka-C1 PE=1 SV=3) HSP 1 Score: 519.62 bits (1337), Expect = 0.000e+0 Identity = 249/353 (70.54%), Postives = 301/353 (85.27%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNS-YVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T + D + VK FLE+AK+ F DK+ T LD+FE +KTLGTGSFGRV++ HK +K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL+ L Y FKDNSNLYMVLE+V GGEMFSHLR+VG+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GYLK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHF +LKDLLRN+LQ DLT+R+GN++ G +DIKN WF S DW + F+K++ APFIP+C+GPGDTSNFD+YEEE L+IS+T KC EF EF
Sbjct: 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRVMIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLYMVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWFASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P05132|KAPCA_MOUSE (cAMP-dependent protein kinase catalytic subunit alpha OS=Mus musculus OX=10090 GN=Prkaca PE=1 SV=3) HSP 1 Score: 516.153 bits (1328), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 305/352 (86.65%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T +LD+F+ +KTLGTGSFGRV+L HK+S ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P36887|KAPCA_PIG (cAMP-dependent protein kinase catalytic subunit alpha OS=Sus scrofa OX=9823 GN=PRKACA PE=1 SV=4) HSP 1 Score: 514.612 bits (1324), Expect = 0.000e+0 Identity = 244/352 (69.32%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K+++P Q T LD+FE +KTLGTGSFGRV+L HK++ + A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P27791|KAPCA_RAT (cAMP-dependent protein kinase catalytic subunit alpha OS=Rattus norvegicus OX=10116 GN=Prkaca PE=1 SV=2) HSP 1 Score: 514.227 bits (1323), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T +LD F+ +KTLGTGSFGRV+L HK+S ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWEDPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Match: sp|P17612|KAPCA_HUMAN (cAMP-dependent protein kinase catalytic subunit alpha OS=Homo sapiens OX=9606 GN=PRKACA PE=1 SV=2) HSP 1 Score: 514.227 bits (1323), Expect = 0.000e+0 Identity = 243/352 (69.03%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T LD+FE +KTLGTGSFGRV+L HK++ ++A+K+LDK K+VKLKQ+EHTLNEKRILQA++FPFL+KL++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPK +GPGDTSNFD+YEEE +++S KC EF EF
Sbjct: 1 MGNAAAAKKGSEQES-VKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A0X3NYD4 (cAMP-dependent protein kinase catalytic subunit alpha OS=Schistocephalus solidus OX=70667 GN=KAPCA PE=3 SV=1) HSP 1 Score: 541.576 bits (1394), Expect = 0.000e+0 Identity = 261/352 (74.15%), Postives = 309/352 (87.78%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN KR E + VK FL++AKK+F +K++ P Q T LD+F+ LKTLGTGSFGRV+L HK K Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL+KL+Y FKDNSNLYMVLEFVNGGEMFSHLR++G+FSE+HA+FYASQVVLAFEYLHHL+L+YRDLKPENILID +GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPF+ADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG SDIKNH WF DW+S +K+EL APF+PKC+GPGD SNFD+YEEE L+I+TT KC +F EF
Sbjct: 1 MGNAAASKRGEPAD--VKAFLDDAKKDFLEKWEKPSQNTACLDDFDRLKTLGTGSFGRVMLVQHKAKKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVKLEYHFKDNSNLYMVLEFVNGGEMFSHLRKIGRFSEHHARFYASQVVLAFEYLHHLELVYRDLKPENILIDQQGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFYADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVSDIKNHKWFAPTDWFSIYKRELEAPFMPKCKGPGDASNFDDYEEEPLRIATTEKCVKDFAEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JWR5 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma japonicum OX=6182 GN=EWB00_007721 PE=2 SV=1) HSP 1 Score: 537.724 bits (1384), Expect = 0.000e+0 Identity = 259/352 (73.58%), Postives = 305/352 (86.65%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ D + VK LEEAKK F +K++ P Q T LD F+ +KTLGTGSFGRV+L HK SK+Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE+H++FYASQVVLAFEYLHHL+L+YRDLKPENILID GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYE+IV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW+S FK+++ APF PKC G GD SNFD+YEEE L+I+TT KC EF EF
Sbjct: 1 MGNAQTAKKG--DPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: A0A1S3JGB8 (cAMP-dependent protein kinase catalytic subunit isoform X12 OS=Lingula unguis OX=7574 GN=LOC106173017 PE=3 SV=1) HSP 1 Score: 536.184 bits (1380), Expect = 0.000e+0 Identity = 255/353 (72.24%), Postives = 309/353 (87.54%), Query Frame = 2
Query: 116 MGNTPTVKR-DEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ D +N VK FL +AK FSDK++ P Q T LD+FE +KTLGTGSFGRV+L HK+SK+Y+A+K+LDK K+VKLKQVEHTLNEKRILQA+ FPFL+ L+Y FKDNSNLYMVLEFV GGEMFSHLRR+G+FSE+H++FYASQ+VLAFEYLH LDL+YRDLKPENILID+ G+LK+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIKNH WF + DW + ++K++ APFIPKC+GPGD SNFD+YEEE L+IS+T KC EF +F
Sbjct: 1 MGNAQTAKKLDPAEN--VKAFLAQAKAEFSDKWEKPSQNTAGLDDFERIKTLGTGSFGRVMLVQHKQSKQYYAMKILDKQKVVKLKQVEHTLNEKRILQAVSFPFLVSLEYHFKDNSNLYMVLEFVTGGEMFSHLRRIGRFSESHSRFYASQIVLAFEYLHALDLVYRDLKPENILIDSSGWLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYQKKVEAPFIPKCKGPGDASNFDDYEEEPLRISSTEKCAKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: D2JVC2 (cAMP-dependent protein kinase catalytic subunit OS=Schistosoma haematobium OX=6185 PE=2 SV=1) HSP 1 Score: 535.798 bits (1379), Expect = 0.000e+0 Identity = 257/352 (73.01%), Postives = 303/352 (86.08%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ D + VK LEEAKK F +K++ P Q T LD F+ +KTLGTGSFGRV+L HK SK+Y+A+K LDK K+VKLKQVEHTLNEKRILQAI FPFL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE+H++FYASQVVLAFEYLHHL+L+YRDLKPEN+LID GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYE+IV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW+S FK+++ APF PKC G GD SNFD+YEEE L+I+TT KC EF EF
Sbjct: 1 MGNAQAAKKG--DPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKTLDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENVLIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Match: C7DPD5 (Serine/threonine kinase; cAMP-dependent protein kinase catalytic subunit OS=Schistosoma mansoni OX=6183 PE=2 SV=1) HSP 1 Score: 535.798 bits (1379), Expect = 0.000e+0 Identity = 258/352 (73.30%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ D + VK LEEAKK F +K++ P Q T LD F+ +KTLGTGSFGRV+L HK SK+Y+A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE+H++FYASQVVLAFEYLHHL+L+YRDLKPENILID GYLKITDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYE+IV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIK H WF + DW+S FK+++ APF PKC G GD SNFD+YEEE L+I+TT KC EF EF
Sbjct: 1 MGNAQAAKKG--DPADVKALLEEAKKEFLEKWEKPAQNTATLDSFDRIKTLGTGSFGRVMLVQHKVSKEYYAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSESHSRFYASQVVLAFEYLHHLELVYRDLKPENILIDQYGYLKITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYERIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKTHKWFATTDWFSIFKRDIEAPFTPKCSGAGDASNFDDYEEEPLRIATTEKCAKEFSEF 350
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103024963]) HSP 1 Score: 524.628 bits (1350), Expect = 0.000e+0 Identity = 246/352 (69.89%), Postives = 305/352 (86.65%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN PT K + VK FL +AK++F K+++P Q T LD+FE LKTLGTGSFGRV+L HK++ ++ A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L++SFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG SDIK H WF + DW + +++++ APFIPKC+GPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNAPTAKNKGNEMESVKEFLAKAKEDFLKKWENPAQNTASLDQFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEHSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFTEKCGKEFAEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacab (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:103023241]) HSP 1 Score: 521.546 bits (1342), Expect = 0.000e+0 Identity = 242/352 (68.75%), Postives = 305/352 (86.65%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGNTP KR + S V+ FL A+++F K++ P Q T LD+F++LKTLGTGSFGRV+L H+++ +++A+K+L+K K+VKLKQ+EHTLNEKRILQA+ FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYASQ+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI IYEKIV+ K++FPSHFS +LK+LLRN+LQ DLT+R+GN++NG +DIK H WF + DW + +++ + APFIPKCRGPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNTPAAKRGNEMES-VREFLALAREDFLRKWETPAQNTASLDQFDLLKTLGTGSFGRVMLVRHRENGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEYSFKDNSNLYMVMEYVQGGEMFSHLRRIGRFSEPHARFYASQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIHIYEKIVSGKVRFPSHFSSDLKELLRNLLQVDLTKRYGNLKNGVNDIKGHKWFSTTDWIAIYQRRVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCGKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000050353.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 520.005 bits (1338), Expect = 0.000e+0 Identity = 247/352 (70.17%), Postives = 306/352 (86.93%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T LD+FE LKTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L+Y+FKDNSNLYMV+E+V GGEMFSHLRR+G+FSE+HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ AP IPKCRGPGDTSNFD+YEEE ++IS T KC EF+EF
Sbjct: 1 MGNAAAAKKGNELES-VKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: prkacbb (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:103034112]) HSP 1 Score: 518.85 bits (1335), Expect = 0.000e+0 Identity = 247/352 (70.17%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN K+ + S VK FL +AK++F K++ P Q T LD+FE LKTLGTGSFGRV+L HK ++++ A+KVLDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L+YSFKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIKNH WF + DW + +++++ APFIPKCRGPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNAAAAKKGNELES-VKEFLAKAKEDFLRKWECPPQSTTTLDDFERLKTLGTGSFGRVMLVKHKGTEQFFAMKVLDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEDIRVSVTEKCAKEFTEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Match: ENSAMXT00000056663.1 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:103029308]) HSP 1 Score: 514.227 bits (1323), Expect = 0.000e+0 Identity = 241/336 (71.73%), Postives = 299/336 (88.99%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+K FL +AK++F K++ P Q T LD+FE LKTLGTGSFGRV+L HK +++Y+A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L+Y+FKDNSNLYMV+E+V GGEMFSHLRR+G+FSE+HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ AP IPKCRGPGDTSNFD+YEEE ++IS T KC EF+EF
Sbjct: 60 MKEFLAKAKEDFLRKWECPPQSTTCLDDFERLKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYERKVEAPIIPKCRGPGDTSNFDDYEEEEIRISDTEKCAKEFLEF 395
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001814.1 (pep scaffold:Pmarinus_7.0:GL481074:830:17391:1 gene:ENSPMAG00000001637.1 transcript:ENSPMAT00000001814.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 462.225 bits (1188), Expect = 5.545e-164 Identity = 203/267 (76.03%), Postives = 245/267 (91.76%), Query Frame = 2
Query: 371 QVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
QVEHTLNEKRILQAI FPFL++L+YSFKDNSNLYMVLE+V GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APFIPKC+GPGD SNFD+YEEE ++IS+T KC EF +F
Sbjct: 22 QVEHTLNEKRILQAISFPFLVRLEYSFKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYQRKVEAPFIPKCKGPGDASNFDDYEEEEIRISSTEKCAKEFADF 288
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000002200.1 (pep scaffold:Pmarinus_7.0:GL479132:31244:36905:-1 gene:ENSPMAG00000001993.1 transcript:ENSPMAT00000002200.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 250.366 bits (638), Expect = 4.899e-80 Identity = 121/296 (40.88%), Postives = 185/296 (62.50%), Query Frame = 2
Query: 248 FEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIK-GR-TWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIV--AAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEV 1123
+++ TLG G FGRV L K S A+K L K +V+ +Q EH +EKRILQ PF+++ +F+D +++++E GGE++S LR G F E A+F + VV A YLH ++YRDLKPEN+L+D +GY+K+ DFGFAK++ GR WT CGTPEY+ PE+I+++G++ D WALG+L++E+ AG PPF P+K Y I+ ++ FP+ +D++R + + + + R GN ++G D++ H WF FDW S +L +P + GP D NFD + E++
Sbjct: 34 MDVIATLGVGGFGRVQLVKLKDSDVTFALKCLKKKFVVESRQQEHVYSEKRILQECSCPFIVRFYRTFRDQKFVFLLMEACLGGELWSVLRDSGGFQEVSARFCVACVVEALAYLHARGILYRDLKPENLLLDARGYIKMADFGFAKKLACGRKAWTFCGTPEYVCPEMIVNRGHDRGADCWALGVLVYELLAGVPPFSGTDPMKTYNAILWGMERVHFPNEVGKRAEDIIRRLCRQNPSERLGNQKHGVGDVRKHKWFQGFDWESLRSNQLASPLKREVSGPTDFKNFDWFPEDL 329
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000004852.1 (pep scaffold:Pmarinus_7.0:GL488704:3417:7135:1 gene:ENSPMAG00000004407.1 transcript:ENSPMAT00000004852.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 230.335 bits (586), Expect = 1.504e-74 Identity = 118/168 (70.24%), Postives = 148/168 (88.10%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKI 667
VK FL +AK++F K+++P+Q T LD+FE +KTLGTGSFGRV+L HK + +Y A+K+LDK K+VKLKQVEHTLNEKRILQAI FPFL+ L+YS+KDNSNLYMVLE+V GGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH LDLIYRDLKPEN+LID +GY+++
Sbjct: 16 VKEFLAKAKEDFLKKWENPQQNTSCLDDFERMKTLGTGSFGRVMLVKHKATDRYFAMKILDKQKVVKLKQVEHTLNEKRILQAISFPFLVSLEYSYKDNSNLYMVLEYVPGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDQQGYIQV 183
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008480.1 (pep scaffold:Pmarinus_7.0:GL482122:191709:206473:1 gene:ENSPMAG00000007654.1 transcript:ENSPMAT00000008480.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 235.728 bits (600), Expect = 8.951e-73 Identity = 127/312 (40.71%), Postives = 183/312 (58.65%), Query Frame = 2
Query: 239 LDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLH-HLDLIYRDLKPENILIDTKGYLKITDFGFAKR--IKGRTW-TLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEF 1162
++ F+ LK LG G+FG+VIL K + +Y+A+K+L K IV +V HTL E R+LQ PFL L YSF+ + L V+E+VNGGE+F HL R FSE+ +FY +++V A +YLH +++YRDLK EN+++D G++KI DFG K G T T CGTPEYLAPE++ Y AVDWW LG++++EM G PF+ K++E I+ I+FP S + + LL +L+ D +R G + A +I H +F W + +++ PF P+ DT FD EE + T D F
Sbjct: 147 MNNFDYLKLLGKGTFGKVILVREKATGQYYAMKILKKEVIVAKDEVAHTLTENRVLQTTKHPFLTLLKYSFQTHDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHTEKNVVYRDLKLENLMLDKDGHIKIADFGLCKEGITDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIRFPRTLSNDARALLSGLLKKDPKQRLGGGVDDAKEIMRHSFFAGIIWQDVYDRKMTPPFKPQVASETDTRYFD---EEFTAQTITITPPDRF 455
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Match: ENSPMAT00000006766.1 (pep scaffold:Pmarinus_7.0:GL478342:9725:27922:-1 gene:ENSPMAG00000006086.1 transcript:ENSPMAT00000006766.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 232.646 bits (592), Expect = 3.437e-72 Identity = 127/324 (39.20%), Postives = 192/324 (59.26%), Query Frame = 2
Query: 236 KLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRIL-QAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKR---IKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFD-NYEEEVLKI--------STTCKCTDEFVE 1168
K +F+ L LG GSFG+V+LA HK ++AVKV+ K I++ K+ +H + E+ +L + + PFL+ L YSF+ LY V+++VNGGE+F HL+R G F E+ A+FYA+++ A YLH L+++YRDLKPENIL+D +G++ +TDFG K T T CGTPEYLAPE++ Y+ VDWW LG +++EM G PPF++ ++YE I+ ++ + +L +L D +R G + +IKNHV+F + +W K + +P+ P GP D NFD + E L + S+ C DE +
Sbjct: 88 KPSDFDFLTVLGKGSFGKVLLAKHKSDGIFYAVKVMKKSIILQKKEEKHIMAERNVLVKNVRHPFLVGLHYSFQSADKLYFVMDYVNGGELFFHLQRQGSFPESRAQFYAAEIGSAIGYLHSLNIVYRDLKPENILLDYQGHIVLTDFGLCKEGIDPHSTTCTFCGTPEYLAPEVLKKHPYDRTVDWWCLGCVLYEMLYGLPPFYSKNLKQMYESILHQPLQLRPCTTNAAISVLEGLLHKDPHQRLGATSD-ILEIKNHVFFSTINWNDLDAKRIPSPYNPGVSGPCDLHNFDPAFTAEPLSMSMAQSSDTSSVCANVDEAAD 410
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK2 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk3p; localizes to P-bodies during stationary phase; relocalizes to the cytosol in response to hypoxia [Source:SGD;Acc:S000006124]) HSP 1 Score: 325.094 bits (832), Expect = 6.591e-109 Identity = 156/299 (52.17%), Postives = 221/299 (73.91%), Query Frame = 2
Query: 233 YKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPK-CRGPGDTSNFDNYEEEVL 1126
Y L +F+I++TLGTGSFGRV L + +Y+A+KVL K ++VK+KQVEHT +E+R+L+ ++ PFLI++ +F+D N++MV++++ GGE+FS LR+ +F AKFYA++V+LA EYLH ++IYRDLKPENIL+D G++KITDFGFAK ++ TWTLCGTP+Y+APE+I +K YN +VDWW+LG+LI+EM AGY PF+ P+K YEKI+ K+ +P +F P++ DLL ++ DLTRR GN+++G+ DIK H WF W K++ P+ P G GDTS FD Y EE L
Sbjct: 65 YTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERRMLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILALEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTKPYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLITADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPEEQL 363
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK3 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; partially redundant with Tpk1p and Tpk2p; localizes to P-bodies during stationary phase; TPK3 has a paralog, TPK1, that arose from the whole genome duplication [Source:SGD;Acc:S000001649]) HSP 1 Score: 313.153 bits (801), Expect = 5.523e-104 Identity = 150/297 (50.51%), Postives = 214/297 (72.05%), Query Frame = 2
Query: 233 YKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKC-RGPGDTSNFDNYEEE 1120
Y L +F+IL+TLGTGSFGRV L + +++A+K L K IVKLKQVEHT +E+R+L + PF+I++ +F+D+ ++MV++++ GGE+FS LR+ +F AKFYA++V LA EYLH D+IYRDLKPENIL+D G++KITDFGFAK + T+TLCGTP+Y+APE++ +K YN +VDWW+ G+LI+EM AGY PF+ +K YE I+ A++KFP F P+ +DLL+ ++ DL+ R GN++NG+ D+KNH WF+ W + + P+ P +G GDTS FD Y EE
Sbjct: 83 YSLSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVSHPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSVDWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSERLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEE 379
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: TPK1 (cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; phosphorylates and inhibits Whi3p to promote G1/S phase passage; partially redundant with Tpk2p and Tpk3p; phosphorylates pre-Tom40p, which impairs its import into mitochondria under non-respiratory conditions; TPK1 has a paralog, TPK3, that arose from the whole genome duplication [Source:SGD;Acc:S000003700]) HSP 1 Score: 311.997 bits (798), Expect = 1.562e-103 Identity = 148/297 (49.83%), Postives = 214/297 (72.05%), Query Frame = 2
Query: 233 YKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKC-RGPGDTSNFDNYEEE 1120
Y L +F+IL+TLGTGSFGRV L + + +Y+A+KVL K +V+LKQVEHT +E+ +L + PF+I++ +F+D ++M+++++ GGE+FS LR+ +F AKFYA++V LA EYLH D+IYRDLKPENIL+D G++KITDFGFAK + T+TLCGTP+Y+APE++ +K YN ++DWW+ GILI+EM AGY PF+ +K YEKI+ A+++FP F+ ++KDLL ++ DL++R GN++NG D+KNH WF W + + P+ P +G GDTS FD Y EE
Sbjct: 82 YSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAMKVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKILNAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIETPYEPPIQQGQGDTSQFDKYPEE 378
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK1 (S/T protein kinase; phosphorylates, downregulates flippase activator Fpk1p; inactivates Orm1p and Orm2p by phosphorylation in response to compromised sphingolipid synthesis; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); mutations affect receptor-mediated endocytosis and sphingolipid-mediated and cell integrity signaling pathways; human homolog SGK1 can complement a null mutant; human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000001609]) HSP 1 Score: 271.166 bits (692), Expect = 1.538e-84 Identity = 137/330 (41.52%), Postives = 202/330 (61.21%), Query Frame = 2
Query: 185 AKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAK---RIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFV 1165
K N S Y + + +D+F++LK +G GSFG+V+ K ++K +A+K + K IV +V HTL E+ +L +D PF++ L +SF+ LY VL F+NGGE+F HL++ G+F + A+FY ++++ A + LH LD++YRDLKPENIL+D +G++ + DFG K + +T T CGTPEYLAPE+++ GY AVDWW LG+L++EM G PP++ + K+Y+KI+ + FP F + KDLL +L D TRR G NGA +I+NH +F W K I P+ P DTSNFD EE + DE++
Sbjct: 326 GKINISIDYKPSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELLCALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPELLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDLLIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFD---EEFTREKPIDSVVDEYL 650
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Match: YPK2 (Protein kinase similar to S/T protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; involved in the TORC-dependent phosphorylation of ribosomal proteins Rps6a/b (S6); human homolog SGK2 can complement a ypk1 ypk2 double mutant [Source:SGD;Acc:S000004710]) HSP 1 Score: 266.544 bits (680), Expect = 8.261e-83 Identity = 137/330 (41.52%), Postives = 201/330 (60.91%), Query Frame = 2
Query: 185 AKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAK---RIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFV 1165
K N + Y K + +D+F++LK +G GSFG+V+ K ++K +A+K L K IV +V HTL E+ +L +D PF++ L +SF+ LY+VL F+NGGE+F HL+ G+FS ++FY ++++ A + LH LD+IYRDLKPENIL+D +G++ + DFG K + +T T CGTPEYLAPEI++ +GY VDWW LGIL++EM G PP++ + +Y+KI+ + FP F P KDLL +L D +RR G NG +I+NH +F W K I P+ P + DT+NFD +E K DE++
Sbjct: 323 GKLNITVDYKPSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAERTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELLCALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPEILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDLLIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFD---QEFTKEKPIDSVVDEYL 647
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO35228 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SM62]) HSP 1 Score: 332.798 bits (852), Expect = 3.209e-112 Identity = 157/301 (52.16%), Postives = 220/301 (73.09%), Query Frame = 2
Query: 221 KQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHF-SPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEE 1120
K + L +FE+ KTLGTG+FGRV+LA ++ +++A+K+++ ++++LKQVEH NEK IL +I+ PF++ L ++ D + LYM+LE+ GGE+F++LR G+F+ F+ S++V A +YLH ++YRDLKPENIL+D G++K+TDFGFAK + +TWTLCGTPEYLAPEII SKG+N AVDWWALGILI+EM GYPPFF D P IYEKI++ K+++P H + KDL++ +L D TRR G+M+NG+ D+KNH WF DW +++L P PK PGDT NFD+Y EE
Sbjct: 9 KDKRTTLQDFELSKTLGTGTFGRVLLARDRRGGEFYALKIMNISEVIRLKQVEHVQNEKNILMSIEHPFIVNLLWTQHDQTFLYMLLEYACGGELFTYLRTAGRFNNGTGLFFGSEIVSAMDYLHGHSIVYRDLKPENILLDRDGHVKLTDFGFAKEVHDKTWTLCGTPEYLAPEIIQSKGHNKAVDWWALGILIYEMLVGYPPFFDDNPFGIYEKILSGKVEWPKHMDNTSAKDLIKKLLVHDRTRRLGSMKNGSEDVKNHKWFKVIDWNLVLQRKLKPPINPKISHPGDTRNFDDYPEE 309
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO41166 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S521]) HSP 1 Score: 244.202 bits (622), Expect = 1.966e-76 Identity = 124/312 (39.74%), Postives = 177/312 (56.73%), Query Frame = 2
Query: 194 NFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILAL----HKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRI---KGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDN 1108
S++ +PK E + FE+LK LG G +G+V L H K K + + I K HT E+ IL+ + PF++ L Y+F+ LY++LE+++GGE+F L R G F E+ A FY S++ +A E+LH ++YRDLKPENIL+D G++K+TDFG K T T CGT EY+APEI+ G+ AVDWW+LG L+++M G PPF AD K +KI+ K+ P + +PE KD +R +L+ R G M A+ IK H +F W K++ PF P G D S FD+
Sbjct: 47 QLSEETVNPKDEKVGPESFELLKVLGKGGYGKVFLVKKNHGHSKEKIFAMKVLKKAAIIRSQKDTAHTKAERNILECVKHPFIVDLIYAFQTGGKLYLILEYLSGGELFMQLEREGIFLEDTACFYLSEISMALEHLHKQGIVYRDLKPENILLDANGHVKLTDFGLCKESIFENSLTHTFCGTIEYMAPEILTRSGHGKAVDWWSLGALMYDMLTGTPPFCADNRKKTIDKILKGKLIIPPYLTPEAKDFIRKLLKRHPQARLGGMAGDANPIKAHSFFRHICWEDLLAKKVEPPFRPSISGEEDVSQFDS 358
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38407 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCZ7]) HSP 1 Score: 250.366 bits (638), Expect = 2.539e-76 Identity = 133/335 (39.70%), Postives = 202/335 (60.30%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAK--KNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIK-GR-TWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAA--KIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNF 1102
+GN ++RD+ D+S + + A + D++ +L++ ++KTLG G FGRV L K+ A+K L K IV+ +Q +H ++EK+I+ + PF+++L +FKD LYM+LE GGE+++ LR G F ++ +FY V+ AF+YLH ++YRDLKPEN+L+D GY K+ DFGFAK+I GR TWT CGTPEY+APEII++KG++ + D+W+LGIL++E+ G PPF P+K Y I+ I FP + L++ + + + R G + G DI H WF F+W ++L +P PK + P D SNF
Sbjct: 311 IGNLDDIQRDQYDDSQRGVDPQTASHLRAQQDEF-----ANVRLEDLTVVKTLGIGGFGRVELVQVAGDKRTFALKTLKKHHIVETRQQDHIMSEKKIMMESNSPFIVRLHKTFKDKKYLYMLLEVCLGGELWTILRDRGSFDDSTTRFYVGCVIEAFQYLHSKGIVYRDLKPENLLLDGHGYCKLVDFGFAKKIGFGRKTWTFCGTPEYVAPEIILNKGHDLSADYWSLGILMYELLTGSPPFSGTDPMKTYNIILKGIDMIDFPRKITRNAHALIKKLCRDNPVERLGYQKGGLKDIMKHKWFDGFNWDGLRSRKLNSPIAPKIKSPVDASNF 640
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO37800 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SEW2]) HSP 1 Score: 241.506 bits (615), Expect = 1.322e-75 Identity = 122/294 (41.50%), Postives = 185/294 (62.93%), Query Frame = 2
Query: 236 KLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRIL-QAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKR---IKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFD 1105
K +F LK +G GSFG+V L+ +K+ K++A+KVL+K I K + +H + E+ +L Q + PFL+ L YSF+ LY VL++VNGGE+F HL+R F E+ A+FYA+++ A YLH L +IYRDLKPENIL+D+KG++ +TDFG K G T T CGTPEYLAPE++ + Y+ +VDWW LG +++EM G PPF++ ++Y+ I+ ++ ++ S + +L +LQ D T+R G+ DI+ H +F S +W + + P+ P G D +FD
Sbjct: 70 KPSDFLFLKVIGKGSFGKVFLSKNKQEDKFYAIKVLNKSAIRKRNEAKHIMAERNVLVQNVTHPFLVGLHYSFQTKDKLYFVLDYVNGGELFFHLQRERYFPESRARFYAAEIASAIGYLHGLQIIYRDLKPENILLDSKGHIVLTDFGLCKEGIDRSGTTSTFCGTPEYLAPEVLRKQDYDKSVDWWCLGAVLYEMMYGLPPFYSRDTAEMYDNILHKPLRLRTNISQSARHILEGLLQKDKTKRLGSGEGDFEDIRTHSFFRSINWQQLVARGIEPPYNPNVSGQLDLKHFD 363
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Match: EDO38399 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7SCY8]) HSP 1 Score: 226.483 bits (576), Expect = 2.471e-67 Identity = 123/293 (41.98%), Postives = 178/293 (60.75%), Query Frame = 2
Query: 143 DEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALH--KKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRI-KGR-TWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAA--KIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNH 1003
DEK + L + E ++ S ++ L++ E++ TLGTG FGRV L + K KK H + Q EH +EKRIL + PF+ K+ +FKD +YM+LE GGE+++ LR G F + A+F + VV FEYLH ++YRDLKPEN+L+D KGY+K+ DFGFAK+I GR TWT CGTPEY+APEII++KG++ + D+W+LGILIFE+ G PPF + P+K Y I+ ++FP ++L++ + + + R G ++G SDIK H
Sbjct: 301 DEKRGAKRTLDVPEEERKVSKEFAD-----LTLEDLEVVATLGTGGFGRVELVTYALKCLKKKHILDTR---------QQEHVYSEKRILMETNSPFICKIYRTFKDRKYVYMLLEACLGGELWTILRDRGTFEDATARFCIACVVEGFEYLHSKGIVYRDLKPENLLLDAKGYVKLVDFGFAKKIGSGRKTWTFCGTPEYVAPEIILNKGHDLSSDYWSLGILIFELLTGSPPFSSSDPMKTYNIILRGLDMVEFPKRIGRNPQNLIKRLCKDNPVERLGYQKDGLSDIKKH 579
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: prkacaa (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101163742]) HSP 1 Score: 521.161 bits (1341), Expect = 0.000e+0 Identity = 246/352 (69.89%), Postives = 307/352 (87.22%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGNTPT K+ + S VK FL +AK++F K+++P Q+T LD FE LKTLGTGSFGRV+L HK++ ++ A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L++SFKD SNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN+RNG +DIK H WF + DW + +++++ APFIPKC+GPGDTSNFD+YEEE +++S + KC EF EF
Sbjct: 1 MGNTPTAKKGNEVES-VKEFLAKAKEDFLKKWENPAQQTAALDHFERLKTLGTGSFGRVMLVKHKETGQHFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVQLEHSFKDTSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLRNGVNDIKGHKWFATTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000035979.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 515.383 bits (1326), Expect = 0.000e+0 Identity = 243/354 (68.64%), Postives = 306/354 (86.44%), Query Frame = 2
Query: 116 MGNTPTVKRDEK--DNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ + +++VK FL +AK++F K++ P Q T L++F+ +KTLGTGSFGRV+L HK S++Y A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L+Y+FKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIK H WF + DW + +++++ APFIPKCRGPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNAATAKKGNELESDTFVKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 354
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000007944.2 (protein kinase cAMP-activated catalytic subunit beta [Source:NCBI gene;Acc:101160305]) HSP 1 Score: 513.842 bits (1322), Expect = 0.000e+0 Identity = 244/352 (69.32%), Postives = 303/352 (86.08%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGNT T K+ + S VK FL +AK++F K++ P Q T LD+FE KTLGTGSFGRV+L HK + +++A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L Y+FKDNSNLYMV+E+V GGEMFSHLRR G+FSE+HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAK++KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+RFGN++NG +DIKNH WF + DW + +++++ APF+PKCRGPGDTSNFD+YEEE + +S T KC EF +F
Sbjct: 1 MGNTATAKKGNEQES-VKEFLAKAKEDFLRKWECPPQCTTSLDDFERFKTLGTGSFGRVMLVKHKATNQFYAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLVYAFKDNSNLYMVMEYVPGGEMFSHLRRTGRFSEHHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQHGYIQVTDFGFAKKVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFSTTDWIAIYERKIEAPFLPKCRGPGDTSNFDDYEEEDIHVSQTEKCGKEFADF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000033457.1 (cAMP-dependent protein kinase catalytic subunit beta [Source:NCBI gene;Acc:101170876]) HSP 1 Score: 513.842 bits (1322), Expect = 0.000e+0 Identity = 244/352 (69.32%), Postives = 304/352 (86.36%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN T K+ + S VK FL +AK++F K++ P Q T L++F+ +KTLGTGSFGRV+L HK S++Y A+K+LDK K+VKLKQ+EHTLNEKRILQA+ FPFL++L+Y+FKDNSNLYMV+E+V GGEMFSHLRR+G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIK H WF + DW + +++++ APFIPKCRGPGDTSNFD+YEEE +++S T KC EF EF
Sbjct: 1 MGNAATAKKGNELES-VKEFLAKAKEDFLRKWECPPQSTTCLEDFDRIKTLGTGSFGRVMLVKHKSSEQYFAMKILDKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHHGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFATTDWIAIYERKVEAPFIPKCRGPGDTSNFDDYEEEEIRVSLTEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Match: ENSORLT00000040218.1 (cAMP-dependent protein kinase catalytic subunit alpha [Source:NCBI gene;Acc:101160964]) HSP 1 Score: 511.916 bits (1317), Expect = 0.000e+0 Identity = 237/352 (67.33%), Postives = 307/352 (87.22%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGN PT ++ + S VK FL +AK++F K+++P Q T L++FE LKTLGTGSFGRV+L H+++ +++A+K+L+K K+VKLKQ+EHTLNEKRILQA+ FPFL++L++SFKDN+NLYMV+E+V GGEMFSHLR++G+FSE HA+FYA+Q+VL FEYLH LDLIYRDLKPEN+LID +GY+++TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+L++EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++NG +DIK H WF + DW + F+K++ APF+PK +GPGDTSNFD+YEEE +++S + KC EF EF
Sbjct: 1 MGNAPTARKGNEMES-VKEFLAKAKEDFLKKWENPSQNTANLEQFERLKTLGTGSFGRVMLVKHRETGQHYAMKILNKQKVVKLKQIEHTLNEKRILQAVSFPFLVRLEFSFKDNTNLYMVMEYVPGGEMFSHLRKIGRFSEPHARFYATQIVLTFEYLHALDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKGHKWFAATDWIAIFQKKVEAPFVPKFKGPGDTSNFDDYEEEEIRVSFSEKCAKEFAEF 351
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000016651.1 (SMESG000016651.1) HSP 1 Score: 699.508 bits (1804), Expect = 0.000e+0 Identity = 352/352 (100.00%), Postives = 352/352 (100.00%), Query Frame = 2
Query: 116 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAVKVLDKLKIVKLKQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF
Sbjct: 1 MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAVKVLDKLKIVKLKQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 352
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 518.85 bits (1335), Expect = 0.000e+0 Identity = 250/341 (73.31%), Postives = 300/341 (87.98%), Query Frame = 2
Query: 149 KDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+D+S VK FLEEAK+ F +K+D P Q T +L +FE L+TLGTGSFGRV+L HK +K+Y A+K+LDK K+VKLKQVEHTLNEKRILQAI F FL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GY+K+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++N DIK H WF + DW + FKKEL APFIP +GPGD+SNFD+YEEE L+I+ T KC EF +F
Sbjct: 168 RDDS-VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 507
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 516.924 bits (1330), Expect = 1.530e-180 Identity = 247/336 (73.51%), Postives = 296/336 (88.10%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+K FLEEAK+ F +K+D P Q T +L +FE L+TLGTGSFGRV+L HK +K+Y A+K+LDK K+VKLKQVEHTLNEKRILQAI F FL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GY+K+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++N DIK H WF + DW + FKKEL APFIP +GPGD+SNFD+YEEE L+I+ T KC EF +F
Sbjct: 247 MKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 582
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000038292.1 (SMESG000038292.1) HSP 1 Score: 518.464 bits (1334), Expect = 2.050e-180 Identity = 248/336 (73.81%), Postives = 296/336 (88.10%), Query Frame = 2
Query: 164 VKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFHSFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
VK FLEEAK+ F +K+D P Q T +L +FE L+TLGTGSFGRV+L HK +K+Y A+K+LDK K+VKLKQVEHTLNEKRILQAI F FL++LDY FKDNSNLYMVLEFVNGGEMFSHLRR+G+FSE H++FYA+Q+VLAFEYLH+LDLIYRDLKPEN+LID++GY+K+TDFGFAKR+KGRTWTLCGTPEYLAPEII+SKGYN AVDWWALG+LI+EMAAGYPPFFADQPI+IYEKIV+ K++FPSHFS +LKDLLRN+LQ DLT+R+GN++N DIK H WF + DW + FKKEL APFIP +GPGD+SNFD+YEEE L+I+ T KC EF +F
Sbjct: 295 VKAFLEEAKRLFVEKWDKPSQNTAQLSDFERLRTLGTGSFGRVMLVQHKVTKEYGAIKILDKQKVVKLKQVEHTLNEKRILQAITFMFLVRLDYHFKDNSNLYMVLEFVNGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQGYIKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSADLKDLLRNLLQVDLTKRYGNLKNNVGDIKTHKWFLNCDWITIFKKELEAPFIPNIKGPGDSSNFDDYEEEPLRIANTEKCLKEFADF 630
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Match: SMESG000000892.1 (SMESG000000892.1) HSP 1 Score: 451.825 bits (1161), Expect = 2.820e-158 Identity = 223/343 (65.01%), Postives = 279/343 (81.34%), Query Frame = 2
Query: 146 EKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTLGTGSFGRVILALHKKSKKYHAXXXXXXXXXXXXXQVEHTLNEKRILQAIDFPFLIKLDYSFKDNSNLYMVLEFVNGGEMFSHLRRVGKFSENHAKFYASQVVLAFEYLHHLDLIYRDLKPENILIDTKGYLKITDFGFAKRIKGRTWTLCGTPEYLAPEIIMSKGYNNAVDWWALGILIFEMAAGYPPFFADQPIKIYEKIVAAKIKFPSHFSPELKDLLRNILQTDLTRRFGNMRNGASDIKNHVWFH-SFDWYSAFKKELIAPFIPKCRGPGDTSNFDNYEEEVLKISTTCKCTDEFVEF 1171
+++N V+ FLE A++ F DK+D P L EF +KTLGTG+FG VIL ++ Y+A+KVL+K KIVK+KQVEHTLNEKRILQA++FPFL+ L YSFKDNS LY+VLE+V GGEMFSHLR+ G++SE A FYASQVV+ FEYLH+LD++YRDLKPENILI+ GY+KITDFGFAKRIKGRTWTLCGTPEYLAPEII+SKGYN AVDWWALGILI+EM GYPPF ADQPI IYEKIV K KFP++ SP+ KDL+R +LQ+DLT+R+GN++NG +DIKNH WF+ + DW + +K++++ PF P+ + GDTS FD+Y+EE LKIS KC EF++F
Sbjct: 8 KENNCEVEEFLENARQEFFDKWDLPVHNNATLAEFTRVKTLGTGTFGTVILVYKPQTDTYYAMKVLNKQKIVKMKQVEHTLNEKRILQAVNFPFLVNLHYSFKDNSYLYLVLEYVVGGEMFSHLRKSGRYSECQANFYASQVVMTFEYLHYLDIVYRDLKPENILINKNGYIKITDFGFAKRIKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGILIYEMIVGYPPFIADQPIHIYEKIVIGKFKFPNYVSPDAKDLIRCLLQSDLTKRYGNLKNGVADIKNHKWFYGNSDWINIYKEKILPPFKPELKSIGDTSYFDDYDEEPLKISKREKCAKEFLDF 350 The following BLAST results are available for this feature:
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 5
BLAST of cAMP-dependent protein kinase catalytic subunit vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034681 ID=SMED30034681|Name=cAMP-dependent protein kinase catalytic subunit|organism=Schmidtea mediterranea sexual|type=transcript|length=1341bpback to top protein sequence of SMED30034681-orf-1 >SMED30034681-orf-1 ID=SMED30034681-orf-1|Name=SMED30034681-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=353bp MGNTPTVKRDEKDNSYVKLFLEEAKKNFSDKYDHPKQETYKLDEFEILKTback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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