von Willebrand factor A domain-containing protein 3A
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Overview
Neoblast Clusters
Zeng et. al., 2018▻ Overview▻ Neoblast Population▻ Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Overview
Single cell RNA-seq of pluripotent neoblasts and its early progeniesWe isolated X1 neoblasts cells enriched in high piwi-1 expression (Neoblast Population), and profiled ∼7,614 individual cells via scRNA-seq. Unsupervised analyses uncovered 12 distinct classes from 7,088 high-quality cells. We designated these classes Nb1 to Nb12 and ordered them based on high (Nb1) to low (Nb12) piwi-1 expression levels. We further defined groups of genes that best classified the cells parsed into 12 distinct cell clusters to generate a scaled expression heat map of discriminative gene sets for each cluster. Expression of each cluster’s gene signatures was validated using multiplex fluorescence in situ hybridization (FISH) co-stained with piwi-1 and largely confirmed the cell clusters revealed by scRNA-seq.We also tested sub-lethal irradiation exposure. To profile rare pluripotent stem cells (PSCs) and avoid interference from immediate progenitor cells, we determined a time point after sub-lethal irradiation (7 DPI) with minimal piwi-1+ cells, followed by isolation and single-cell RNA-seq of 1,200 individual cells derived from X1 (Piwi-1 high) and X2 (Piwi-1 low) cell populations (Sub-lethal Irradiated Surviving X1 and X2 Cell Population)Explore this single cell expression dataset with our NB Cluster Shiny App
Neoblast Population
Sub-lethal Irradiated Surviving X1 and X2 Cell Population
Embryonic Expression
Davies et. al., 2017
Hover the mouse over a column in the graph to view average RPKM values per sample. Embryonic Stages: Y: yolk. S2-S8: Stages 2-8. C4: asexual adult. SX: virgin, sexually mature adult. back to top Anatomical Expression
PAGE et. al., 2020SMED30034618 has been reported as being expressed in these anatomical structures and/or regions. Read more about PAGEPAGE Curations: 9
Homology
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Human
Match: VWA3A (von Willebrand factor A domain containing 3A [Source:HGNC Symbol;Acc:HGNC:27088]) HSP 1 Score: 488.419 bits (1256), Expect = 7.978e-150 Identity = 292/798 (36.59%), Postives = 446/798 (55.89%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKK---NEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSIT--NSKPPYRPVIQS--------------AFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLS---IDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQK 4187
+L+ NA+ EF+P + + V+S+++EKAMIQ EW DG+V+N+H D L++YQ+ L +++ E+RI WLS SRRI+GT+ E++V+++LD+S +N Y++HI SL++L+++QL KD FN+IAF +TI S++ + V+ NLQ +W W +L C GSRN+L AL+ E +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+RYA+ T TA + + + GRFHWF ++GI ESDDI +M+E++ A+ YS++ ++ K +HS K + + K + + S L PPR T AR+ D E K+L ++ + R I+ ++P +++ FYTE N G VY+ YP Q RR +P K+ +S++W+ KY LK + L++ R + GP C H+++ ++ AK+C+ +FP V + G +H+Q+T E+ Y +K L RY++RL+WL+ S+R+FG + E+ V ILLDTSGSM P++ ++ L LIWEQL K S+N+++F + +++ LV +++CH A+ W HL A G+T +ALL ++G+YLLTDGKPD S +VL VQ + R KV HTIS NC D +A EFL++LA + GRYH +D + LL+ I+ P LP EGDDL LA+EI R L + FR QLQK
Sbjct: 425 QVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTP-PARYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMASLK-----NHSGKVLGSSALPKEKPKTLQLRSQPK--KLCPPRPTVPLGARMSIKDDPDREKSPPLKSLKWRP-LSSRVGISPAAAQPTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYP-QGRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCM-GPNCTHQKSG----QRSASAKHCS-IFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKV--HTISLNCSDRAAVEFLRKLASFTGGRYH----------------------------CPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQEITKARSFLWQAQSFRS---QLQK 1173 HSP 2 Score: 227.254 bits (578), Expect = 1.052e-59 Identity = 131/375 (34.93%), Postives = 207/375 (55.20%), Query Frame = 3
Query: 390 KVKNFEIIDRNKKYYPPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
K KN + +N N VT +NQ DLLR+Q + S D + SEDWL H+L +LT+ DLIS+G E+ + + I+ +E KL IE+Y +RI+W + S+K FG + G+++++LID S + G + FQ +L+ L+DEQL K+ + + FGTN L+ D M ++ ++E+K T+ GG NL+QALK + K +D ++ I+ SCPDQ +++L ++QQ +GRDL H ++Y + ++LK +A G YH YS E YTS D+D LL EI++ Q +L ++ ++ + + +I+ E+ N P LPKP + PL E P + +TS+EW
Sbjct: 48 KQKNMNGLGQNSD----NGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGT----EVLEEGTNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKE-EFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEH--YTSRDMDELLAEIQKAQSLLSHVQALQHSSPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLD-KTSAEW 410 HSP 3 Score: 140.969 bits (354), Expect = 5.599e-33 Identity = 186/782 (23.79%), Postives = 331/782 (42.33%), Query Frame = 3
Query: 633 GTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK------YVTKEKSIDE-VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRG-------IFSNRASPYINQIAEELKNIPQSENLPKP-------ISF-NDPLKFEVPKFEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESN------FTRDAN----ISRKSIQGR---RFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHW------------FRESGII----------ESDDIRVLMAEIDLAVEYSRRTQQIINDYKEK 2762
GT N V F+ Y+ +L A+ MY +RI+W SR+++G V ++ VL+D S N + +I Q +L LL+EQL K N+ FG+ + + + ++ ++ + G N++ AL+ + K+K + + L G PDQ+ L ++ + G DL + C+ Y + + + ++ K + + G +H + +Y S+DI+ ++ E+E+ +K + + + A P +L++ P+ P+P +S +DP + + P P S +W S S+ +S A PT ++E+ RE+ +T N + +K QGR R SS+I P K D + ++ +++ G+K+ +++ + N KS G+ S+ + VE G VR++ ++ Y + L + ++ QR+ WL +GSRR+FGT++E KV ++LD S S YL + L +LI +Q K D FN+++F+ + S++ L + ++ W+ L GS ++L AL F S H+ +G+YL T G PD ++ +++ D+K+HT+ N D R A E +R LA T GR+H G I E DD+R+L EI A + + Q + ++K
Sbjct: 463 GTVKNIHVDPPFLY-KYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMY--IIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTG---IYESDDINSIMSEMEKALNYSQKCAFLMASLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSP---PLKSLKWRPLS----------SRVGISPAAAQ-----PTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSSIDLPRK---------DTVCSSQEWVAKY-GLKK-------LKLEISRCMGPNCTHQKS------GQRSASAKHCSIFPSVE-IHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAF-----SFHD--LEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSD----------RAA-----VEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQEITKARSFLWQAQSFRSQLQKK 1174 HSP 4 Score: 71.633 bits (174), Expect = 1.160e-11 Identity = 55/255 (21.57%), Postives = 113/255 (44.31%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTD--------------YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFK-KKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYH 1244
SS++W+ + L L+L I + + + +++ +A +C ++ + Y L + Y +R++W L GSR++FG V SK+ +L+D+S + + + + + L+ L+ EQL K S N+ F + + + E + + + + G +++QAL ++ + L+ PD +++ VQ+L RD+ H +S L+ +A+ + G YH
Sbjct: 861 SSQEWVAKYGLKKLKLEISRCMGPN-CTHQKSGQRSASAKHCSIFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQV--KTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYH 1112 HSP 5 Score: 70.0922 bits (170), Expect = 3.019e-11 Identity = 66/283 (23.32%), Postives = 121/283 (42.76%), Query Frame = 3
Query: 3132 EWITSKDWMKKYSLKNMGLDLLRLVS-GPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSG-SMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQ 3974
+W S+DW+ +SLK L L L+S G E E ++ K C ++ + + + + Y +R++WL +SK+ FG+I V+IL+D S S P E +L +LI EQL ++ + +++F + + S+ W + L G ++ +AL + + + PD +EI+ +Q S+ + IH I++ C+D+ LK LA G YH C+ + ++ R +++
Sbjct: 86 DWEDSEDWLSAHSLKCQKLTLADLISQGTEVLEEGTNVV-------QKIC-----------------FSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLF-VLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQ--STMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYH--CYSPKMEHYTSRDMDE 339 HSP 6 Score: 67.0106 bits (162), Expect = 3.172e-10 Identity = 72/286 (25.17%), Postives = 130/286 (45.45%), Query Frame = 3
Query: 2019 YQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIE---SDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMP 2861
++ L + +++ ++RI WL+ S++ FG I +V +++D+S IS+ + L LI +QL K+K +++F S V+ + LQ+ W+++L G NLL ALK +F +DS + PDQ E L YI++ +G D+ IH + + DD +P +++ LA + +G +H + S +E S D+ L+AEI A Q + HS E + E+ ++ +++L+P
Sbjct: 137 FESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDS--------LVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQ------MP---------PAVLKNLAEAVRGYYHCY--SPKMEHYTSRDMDELLAEIQKAQSLLSHVQAL----------QHSSPCEALTCTMEEISTEITNGPLISLLP 387
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Human
Match: VWA3A (von Willebrand factor A domain containing 3A [Source:HGNC Symbol;Acc:HGNC:27088]) HSP 1 Score: 256.529 bits (654), Expect = 1.828e-74 Identity = 146/395 (36.96%), Postives = 233/395 (58.99%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKK---NEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSAFYTE 3035
+L+ NA+ EF+P + + V+S+++EKAMIQ EW DG+V+N+H D L++YQ+ L +++ E+RI WLS SRRI+GT+ E++V+++LD+S +N Y++HI SL++L+++QL KD FN+IAF +TI S++ + V+ NLQ +W W +L C GSRN+L AL+ E +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+RYA+ T TA + + + GRFHWF ++GI ESDDI +M+E++ A+ YS++ ++ K +HS K + + K + + S L PPR T AR+ D E K+L ++ P S P +++ F+++
Sbjct: 35 QVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTP-PARYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMASLK-----NHSGKVLGSSALPKEKPKTLQLRSQPK--KLCPPRPTVPLGARMSIKDDPDREKSPPLKSLKWR----PLSSRVGISPGMAEWLRAEFWSQ 417 HSP 2 Score: 87.8113 bits (216), Expect = 2.999e-17 Identity = 65/218 (29.82%), Postives = 108/218 (49.54%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLE-------DPRIQGIYLLTDGKPDN 3770
TS +W+K LK L L ++++ E + L+K V + + + GT K++ L KY + +A+ Y +R+EWL ++S+RI+G + E V +LLD S + + ++ + +L+ L+ EQL K +N+IAF S I +R +V ++ SA W +L G+ + AL +E + QGIYL T G PD
Sbjct: 16 TSAEWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQL-SNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQ 232 HSP 3 Score: 73.9442 bits (180), Expect = 9.258e-13 Identity = 76/362 (20.99%), Postives = 152/362 (41.99%), Query Frame = 3
Query: 519 EQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQ------------------------TGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK------YVTKEKSIDE-VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRG-------IFSNRASPYINQIAEELKNIPQSENLPKP 1448
+++S +WLK + L A +L++ +++ P E+ GT N V F+ Y+ +L A+ MY +RI+W SR+++G V ++ VL+D S N + +I Q +L LL+EQL K N+ FG+ + + + ++ ++ + G N++ AL+ + K+K + + L G PDQ+ L ++ + G DL + C+ Y + + + ++ K + + G +H + +Y S+DI+ ++ E+E+ +K + + + A P +L++ P+ P+P
Sbjct: 14 DKTSAEWLKVNGLKAKKLSLYQVLAPNAFS---PVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLY-KYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMY--IIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTG---IYESDDINSIMSEMEKALNYSQKCAFLMASLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRP 366
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Human
Match: VWA3A (von Willebrand factor A domain containing 3A [Source:HGNC Symbol;Acc:HGNC:27088]) HSP 1 Score: 240.35 bits (612), Expect = 7.223e-66 Identity = 135/368 (36.68%), Postives = 214/368 (58.15%), Query Frame = 3
Query: 1716 STISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQ---------------------KLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYK 2756
S + KP K + NL + S + G+K ++ +L+ NA+ EF+P + + V+S+++EKAMIQ EW DG+V+N+H D L++YQ + L +++ E+RI WLS SRRI+GT+ E++V+++LD+S +N Y++HI SL++L+++QL KD FN+IAF +TI S++ + V+ NLQ +W W +L C GSRN+L AL+ E +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+RYA+ T TA + + + GRFHWF ++GI ESDDI +M+E++ A+ YS++ ++ K
Sbjct: 384 SLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLKAK-------KLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQWNDYTAWIPRDLTHHSLKPTQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTP-PARYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMASLK 743 HSP 2 Score: 226.098 bits (575), Expect = 4.399e-61 Identity = 131/375 (34.93%), Postives = 207/375 (55.20%), Query Frame = 3
Query: 390 KVKNFEIIDRNKKYYPPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
K KN + +N N VT +NQ DLLR+Q + S D + SEDWL H+L +LT+ DLIS+G E+ + + I+ +E KL IE+Y +RI+W + S+K FG + G+++++LID S + G + FQ +L+ L+DEQL K+ + + FGTN L+ D M ++ ++E+K T+ GG NL+QALK + K +D ++ I+ SCPDQ +++L ++QQ +GRDL H ++Y + ++LK +A G YH YS E YTS D+D LL EI++ Q +L ++ ++ + + +I+ E+ N P LPKP + PL E P + +TS+EW
Sbjct: 48 KQKNMNGLGQNSD----NGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGT----EVLEEGTNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKE-EFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEH--YTSRDMDELLAEIQKAQSLLSHVQALQHSSPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLD-KTSAEW 410 HSP 3 Score: 77.0258 bits (188), Expect = 1.765e-13 Identity = 47/139 (33.81%), Postives = 76/139 (54.68%), Query Frame = 3
Query: 3372 KALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLE-------DPRIQGIYLLTDGKPD 3767
+A+ Y +R+EWL ++S+RI+G + E V +LLD S + + ++ + +L+ L+ EQL K +N+IAF S I +R +V ++ SA W +L G+ + AL +E + QGIYL T G PD
Sbjct: 505 RAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQL-SNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPD 642 HSP 4 Score: 70.4774 bits (171), Expect = 2.223e-11 Identity = 66/283 (23.32%), Postives = 121/283 (42.76%), Query Frame = 3
Query: 3132 EWITSKDWMKKYSLKNMGLDLLRLVS-GPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSG-SMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQ 3974
+W S+DW+ +SLK L L L+S G E E ++ K C ++ + + + + Y +R++WL +SK+ FG+I V+IL+D S S P E +L +LI EQL ++ + +++F + + S+ W + L G ++ +AL + + + PD +EI+ +Q S+ + IH I++ C+D+ LK LA G YH C+ + ++ R +++
Sbjct: 86 DWEDSEDWLSAHSLKCQKLTLADLISQGTEVLEEGTNVV-------QKIC-----------------FSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLF-VLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQ--STMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYH--CYSPKMEHYTSRDMDE 339 HSP 5 Score: 65.855 bits (159), Expect = 4.577e-10 Identity = 77/312 (24.68%), Postives = 139/312 (44.55%), Query Frame = 3
Query: 2019 YQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIE---SDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALM--PPRQTSLSKARLKYLSDKTEENLKI 2933
++ L + +++ ++RI WL+ S++ FG I +V +++D+S IS+ + L LI +QL K+K +++F S V+ + LQ+ W+++L G NLL ALK +F +DS + PDQ E L YI++ +G D+ IH + + DD +P +++ LA + +G +H + S +E S D+ L+AEI A Q + HS E + E+ ++ +++L+ PP+ + L + E LK+
Sbjct: 137 FESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDS--------LVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQ------MP---------PAVLKNLAEAVRGYYHCY--SPKMEHYTSRDMDELLAEIQKAQSLLSHVQAL----------QHSSPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKV 413 HSP 6 Score: 65.0846 bits (157), Expect = 8.969e-10 Identity = 55/244 (22.54%), Postives = 111/244 (45.49%), Query Frame = 3
Query: 684 EYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK------YVTKEKSIDE-VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELM 1352
+ +L A+ MY +RI+W SR+++G V ++ VL+D S N + +I Q +L LL+EQL K N+ FG+ + + + ++ ++ + G N++ AL+ + K+K + + L G PDQ+ L ++ + G DL + C+ Y + + + ++ K + + G +H + +Y S+DI+ ++ E+E+ +K +
Sbjct: 500 QQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMY--IIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTG---IYESDDINSIMSEMEKALNYSQKCAFL 738
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Human
Match: VWA3A (von Willebrand factor A domain containing 3A [Source:HGNC Symbol;Acc:HGNC:27088]) HSP 1 Score: 173.711 bits (439), Expect = 1.485e-47 Identity = 109/302 (36.09%), Postives = 152/302 (50.33%), Query Frame = 3
Query: 3354 YSVEAKKALIRYMKRLEWLMIS------------------------SKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQK 4187
Y +K L RY++RL+WL+ S+R+FG + E+ V ILLDTSGSM P++ ++ L LIWEQL K S+N+++F + +++ LV +++CH A+ W HL A G+T +ALL ++G+YLLTDGKPD S +VL VQ + R KV HTIS NC D +A EFL++LA + GRYH + + SK +L ++D P LP EGDDL LA+EI R L + FR QLQK
Sbjct: 4 YIRHLEKVLRRYVQRLQWLLSGPVLCSRTWYRQSMDRGVMMTAASGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKV--HTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTL----------SKIHSLLTKGFINEKD---------------PTLPPFEGDDLRILAQEITKARSFLWQAQSFRS---QLQK 275 HSP 2 Score: 80.8777 bits (198), Expect = 1.054e-15 Identity = 70/252 (27.78%), Postives = 113/252 (44.84%), Query Frame = 3
Query: 2076 STGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHW------------FRESGII----------ESDDIRVLMAEIDLAVEYSRRTQQIINDYKEK 2762
++GSRR+FGT++E KV ++LD S S YL + L +LI +Q K D FN+++F+ + S++ L + ++ W+ L GS ++L AL F S H+ +G+YL T G PD ++ +++ D+K+HT+ N D E +R LA T GR+H G I E DD+R+L EI A + + Q + ++K
Sbjct: 47 ASGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAF-----SFHD--LEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSD---------------RAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQEITKARSFLWQAQSFRSQLQKK 276 HSP 3 Score: 52.373 bits (124), Expect = 3.124e-6 Identity = 40/168 (23.81%), Postives = 78/168 (46.43%), Query Frame = 3
Query: 744 GSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKK-KSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYH 1244
GSR++FG V SK+ +L+D+S + + + + + L+ L+ EQL K S N+ F + + + E + + + + G +++QAL ++ + L+ PD +++ VQ+L RD+ H +S L+ +A+ + G YH
Sbjct: 49 GSRRLFGTVLESKVCILLDTSGSMGPYLQQV--KTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYH 214
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Human
Match: VWA3B (von Willebrand factor A domain containing 3B [Source:HGNC Symbol;Acc:HGNC:28385]) HSP 1 Score: 137.502 bits (345), Expect = 8.069e-32 Identity = 89/274 (32.48%), Postives = 133/274 (48.54%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALII---------------PLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
SK W++KY LK L L +++ RH + ++ +K V AKYC+ G+ H+ T + YS AL R +R++WL S+ +FG + + IL+DTS SM + + + I EQL K K +N + F+ Q +RE+L +E + A W + +T+T AL D Q IYLLTDG+PD E V+ V+ R ++PI+TISFN DE AN FLK +A ++ G +H
Sbjct: 390 SKTWLQKYGLKAQKLSLYDVLADCSFRHADGVVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQL-KYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQPPETVIDQVK-----RFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFH 657 HSP 2 Score: 99.7525 bits (247), Expect = 3.265e-20 Identity = 76/267 (28.46%), Postives = 128/267 (47.94%), Query Frame = 3
Query: 3138 ITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFP-IVNVKGTRKHLQYTVTELNKYSVEA-KKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHL---VACGNTDTTKALLITLEDPRIQGIYLLTDGK-PDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
I+S+ W++ + LK+ L L +++S H E + L + V ++Y GLFP + + R + +EL VE +A+ Y +R++WL S++IFGVI E V I+LD G + + +L ++ ++ +NII + + +++E E S +AI W E L + ALL D I+ IY G P+ S E++L+ I P++T+SFN E FLK L+ ++ R+H
Sbjct: 34 ISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGEL-DLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEI------PCPVYTVSFNARGEGTIAFLKDLSAKTHSRFH 293 HSP 3 Score: 91.6633 bits (226), Expect = 7.955e-18 Identity = 125/524 (23.85%), Postives = 223/524 (42.56%), Query Frame = 3
Query: 1938 YEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-------ESGIIESDDIRVLMAEI-----DLAVEYSRRTQQIINDY---KEKYPPSHSKKNEDIIKNAVELCRRNSSD-------NMVALMPPRQTSLSKARLKYL--SDKTEENLKIPKTLAYKSD-IDPRKSITNSKPPYR--------PVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQY---TVTELNKYSVEAKKALIRYMKRL 3401
Y + W DGS+ +V+ + Y + + + + +RI WL GS+ +FG + + +++D S S L + + IQ+QLK K KFN + F +++ L VNE NL+ + SW+R + S N L ALK F + Q IYL T G PDQ P I++ +I I+T+ FN +D I +R+ ++ +A T G FH++ ++++D+ +L+ E+ DL ++ +I D+ EK S +K + + E C + SD ++ L P S K + K + ++ T+ +L + + +S RK ++ R ++ + + +DK+S+ V G V ++S++W+K Y L L L+ +S H + L+K+V +K +FP+ +V + +LN Y + ++A+ Y KRL
Sbjct: 448 YCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFA-------DKETQAIYLLTDGRPDQ---PPETVIDQVKRFQEIPIYTISFNYND------EIANRF---------LKEVAALTGGEFHFYNFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTRE-------------GSQVYDHDSSDVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNKMTLINPQGAKLNIYKRKVEQAIQSYEKRL 933 HSP 4 Score: 76.6406 bits (187), Expect = 3.016e-13 Identity = 86/321 (26.79%), Postives = 148/321 (46.11%), Query Frame = 3
Query: 1713 SSTIS-KPVKSRISQILTIDNLKEFSQFGSE----FEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQV-EWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSG-VPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRE 2654
SSTIS + ++ + I T +L E S SE G+K + ++ + ILS+ + +++ S+GR V S + Q+ DG V N+ A ++++ + L + V+ +QR+ WL++ SR+IFG I+E+ V ++LD L ++L +++Q+Q+ +FNII S ++ T V E ++ + SW+ L + + G L + E D + IY F G VP++ E L+ +R L ++TV FN A T ++ L+ T RFH F E
Sbjct: 7 SSTISEQQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSN-------KLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKT----IESIYYFVVGDVPEESKELLL----QRALEIPCPVYTVSFN---------------ARGEGTIAFLKDLSAKTHSRFHAFAE 297 HSP 5 Score: 72.4034 bits (176), Expect = 5.672e-12 Identity = 52/226 (23.01%), Postives = 103/226 (45.58%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYS----SMTEELMYTSNDIDLLLLEIERTQEVLEKIE 1346
Y ++H A+ +RIKW GS+ +FG + + +LID+S + ++ +D ++ + EQL K N F + +N +E+ + + N + ALK +K + L+ PDQ + ++ V++ +++P + +S+ E + LK +A ++ G +H Y+ T + D+ LL+ E+E+ LEK++
Sbjct: 475 YSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMK--SKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQPPETVIDQVKRF---QEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYNFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQ 695 HSP 6 Score: 60.8474 bits (146), Expect = 1.960e-8 Identity = 56/278 (20.14%), Postives = 115/278 (41.37%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISK----------GKLGNPRPDE------------QTGTAYNCLVYDDFIVTDYEYKLHM--AIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSS---DANLGFGR---VISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEV-LLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTE 1265
SSE WL+ H L + +LT++ ++S+ LG P + G YN + I Y++ H+ A+E Y +R+ W SR++FG + + +++D + L R + Q+ + H+ + + + + + T Q V E + ++ + AL ++K+I+ + ++G P++ ++L+ Q L P + VS+ + E + LK ++ +H +H ++ TE
Sbjct: 35 SSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELI---YQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWV-----EKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLL----QRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTE 300
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Zebrafish
Match: vwa3a (von Willebrand factor A domain containing 3A [Source:ZFIN;Acc:ZDB-GENE-131121-527]) HSP 1 Score: 238.039 bits (606), Expect = 1.433e-68 Identity = 124/372 (33.33%), Postives = 200/372 (53.76%), Query Frame = 3
Query: 3051 GVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQ 4166
G V++ YP + R+ I +P E ++K W+K++ ++N+ LDL RL+SGPECRH++ L+ +++ V AKYCA +FP + + G KHL + EL +Y + + ++RY +RL+WL+ S+R+FG + E +V +LLD SGSM PEL L LIW+QL + +N++AF+ + +R LV E C A+ W + G++ T AL G+YL++DG+ D S ++L ++ + R+ +HTI+ NC D S+++FLKRLA + GR+H+ D + +++ + S LP+ EGDDL RL +EIQ R + FR+
Sbjct: 52 GFVFKSYP-KPKSVRKSIASIKLPKHEGICSTKQWLKRFGIRNLHLDLHRLLSGPECRHQDTLVPSVQRRVSAKYCA-IFPSIQINGAVKHLHLSPAELKQYISQTETLMLRYCQRLQWLLTGSRRMFGSVLEKEVCLLLDVSGSMASCFPELQKGLTLLIWDQLHANSVRFNMLAFSRGLCMWRPALVQSTEDQCVHAVQWLSQINTHGSSSTLTALQTACGLADGVGVYLISDGRSDCSHSLILTEMETL--RREKSFTVHTIALNCSDRSSSDFLKRLAHKNGGRFHQAPESTDPDLIREQLSDPSSALNLPE----------------------------FEGDDLKRLTEEIQKLRLFQKQAKAFRE 391 HSP 2 Score: 83.5741 bits (205), Expect = 3.864e-16 Identity = 76/286 (26.57%), Postives = 130/286 (45.45%), Query Frame = 3
Query: 1833 KRF----IEMFTENILSKNAYESKSEFIPSIGRMVTS---SVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLM---EQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRES 2657
KRF + + +LS + +PS+ R V++ +++ I +G+V+++H A+L +Y + + LM QR+ WL TGSRR+FG+++E++V L+LD+S S + + L +LI Q +FN++AFS + ++ L E + WL +N GS + L AL+ D V G+YL + G D ++ +E +HT+ N D +++ ++ LAH GRFH ES
Sbjct: 87 KRFGIRNLHLDLHRLLSGPECRHQDTLVPSVQRRVSAKYCAIFPSIQI-----NGAVKHLHLSPAELKQY---ISQTETLMLRYCQRLQWLLTGSRRMFGSVLEKEVCLLLDVSGSMASCFPELQKGLTLLIWDQLHANSVRFNMLAFSRGLCMWRPALVQSTEDQCVHAVQWLSQINTHGSSSTLTALQTAC-GLADGV------GVYLISDGRSDCSHSLILTEMETLRREKSFTVHTIALNCSDRS---------------SSDFLKRLAHKNGGRFHQAPES 342
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Xenopus
Match: muc4 (mucin 4, cell surface associated [Source:Xenbase;Acc:XB-GENE-852599]) HSP 1 Score: 250.366 bits (638), Expect = 1.955e-73 Identity = 127/291 (43.64%), Postives = 198/291 (68.04%), Query Frame = 3
Query: 1863 ILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRT 2732
IL+ NAY EF+P + + V+S+++E+AM+Q EW DG+V+N+H D L EYQ+ L + + E+RI WL+ GSRR++G + E++V+L++D+S+SN +++HI SL++L+++Q+ KD FNIIAF + I+S+K+ + NLQ +W W+ SLNC G RN+LGA++ E N +D+ N +QGIYLFTSGVPDQ + + AY+ E G+D+++H LF+V + +V + T I++ LAH + GRFHWF E G+IESDDI L++E++ A+ YS +
Sbjct: 58 ILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDN-ENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLT-----EDTNNTTGILKDLAHISNGRFHWFDEKGLIESDDISFLISEMEKAMNYSSKV 342 HSP 2 Score: 99.3673 bits (246), Expect = 1.448e-21 Identity = 80/276 (28.99%), Postives = 127/276 (46.01%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL-------LITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTIS---FNCED--ESANE---FLKRLARMSNGRYH 3920
TS +W+KK LK L L ++++ E + L+K V + + + GT K++ L +Y + K Y KR++WL S+R++G + E V +L+D S S + H+ + +L+ L+ EQ+ + + +NIIAF S+I ++ +V P + A W L G + A+ I E+ QGIYL T G PD V + S ++ + S N ED E N LK LA +SNGR+H
Sbjct: 38 TSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDL-FNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFH 312 HSP 3 Score: 82.0333 bits (201), Expect = 9.116e-16 Identity = 65/256 (25.39%), Postives = 115/256 (44.92%), Query Frame = 3
Query: 633 GTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDE-------VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEV----------SSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIEL 1349
GT N V D ++ +Y+ +L Y KRI W GSR+++G V ++ +L+D S +N +I Q +L LL+EQ+ K NI FG+ + + ++ + +++ GG N++ A++ + ID + L PDQ+ + ++ + G DL H + V + ILK +A IS+G +H + E+ + S+DI L+ E+E+ K+ L
Sbjct: 95 GTVKNIHV-DPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSN--SMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFHWFD---EKGLIESDDISFLISEMEKAMNYSSKVGL 344
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Xenopus
Match: muc4 (mucin 4, cell surface associated [Source:Xenbase;Acc:XB-GENE-852599]) HSP 1 Score: 245.358 bits (625), Expect = 5.605e-70 Identity = 127/291 (43.64%), Postives = 197/291 (67.70%), Query Frame = 3
Query: 1863 ILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRT 2732
IL+ NAY EF+P + + V+S+++E+AM+Q EW DG+V+N+H D L EYQ L + + E+RI WL+ GSRR++G + E++V+L++D+S+SN +++HI SL++L+++Q+ KD FNIIAF + I+S+K+ + NLQ +W W+ SLNC G RN+LGA++ E N +D+ N +QGIYLFTSGVPDQ + + AY+ E G+D+++H LF+V + +V + T I++ LAH + GRFHWF E G+IESDDI L++E++ A+ YS +
Sbjct: 195 ILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQ--LAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDN-ENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLT-----EDTNNTTGILKDLAHISNGRFHWFDEKGLIESDDISFLISEMEKAMNYSSKV 477 HSP 2 Score: 121.324 bits (303), Expect = 5.297e-28 Identity = 61/190 (32.11%), Postives = 108/190 (56.84%), Query Frame = 3
Query: 945 MNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
M LN ++ E ++ + GGCNL++ALK V + + +D +++++ SCPDQ + L ++QQ +GR + H +++++ + + Y+ S GN+ +Y+S DI LLL EI+ VL +I+ MR G+ + + +++ EL+ + S LPKP + + PL E+P F P+TS+EW
Sbjct: 6 MKLN--ILHETRQWIQELQPQGGCNLLRALKRVLQVQELDSLVIVVSSCPDQTEEALSDYIQQCTIGRTIQIHIIAFDSLGQVI-----YLCACSWGNHE---------IYSSTDIQLLLNEIQAAINVLNQIKEMRHGMLGDSLISIMQELSTELEKVSPSAFLPKPPNHDGPLNIEIPNFSPKTSAEW 179 HSP 3 Score: 94.7449 bits (234), Expect = 2.534e-19 Identity = 82/276 (29.71%), Postives = 129/276 (46.74%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL-------LITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTIS---FNCED--ESANE---FLKRLARMSNGRYH 3920
TS +W+KK LK L L ++++ E + L+K V + + + GT K++ L +Y + AK A Y KR++WL S+R++G + E V +L+D S S + H+ + +L+ L+ EQ+ + + +NIIAF S+I ++ +V P + A W L G + A+ I E+ QGIYL T G PD V + S ++ + S N ED E N LK LA +SNGR+H
Sbjct: 175 TSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQL-AKMAR-TYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDL-FNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFH 447 HSP 4 Score: 78.1814 bits (191), Expect = 4.180e-14 Identity = 61/239 (25.52%), Postives = 107/239 (44.77%), Query Frame = 3
Query: 684 EYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDE-------VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEV----------SSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIEL 1349
EY+L Y KRI W GSR+++G V ++ +L+D S +N +I Q +L LL+EQ+ K NI FG+ + + ++ + +++ GG N++ A++ + ID + L PDQ+ + ++ + G DL H + V + ILK +A IS+G +H + E+ + S+DI L+ E+E+ K+ L
Sbjct: 246 EYQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSN--SMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQDLHTVSAYLSEATSGSDLQLHVCLFSVGEMNVEDLTEDTNNTTGILKDLAHISNGRFHWFD---EKGLIESDDISFLISEMEKAMNYSSKVGL 479
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Xenopus
Match: muc4 (mucin 4, cell surface associated [Source:Xenbase;Acc:XB-GENE-852599]) HSP 1 Score: 182.185 bits (461), Expect = 3.638e-49 Identity = 93/200 (46.50%), Postives = 144/200 (72.00%), Query Frame = 3
Query: 1863 ILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQI 2459
IL+ NAY EF+P + + V+S+++E+AM+Q EW DG+V+N+H D L EYQ+ L + + E+RI WL+ GSRR++G + E++V+L++D+S+SN +++HI SL++L+++Q+ KD FNIIAF + I+S+K+ + NLQ +W W+ SLNC G RN+LGA++ E N +D+ N +QGIYLFTSGVPDQ +
Sbjct: 203 ILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDN-ENQESQGIYLFTSGVPDQDL 401 HSP 2 Score: 109.768 bits (273), Expect = 1.350e-24 Identity = 54/161 (33.54%), Postives = 95/161 (59.01%), Query Frame = 3
Query: 756 MFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGN 1238
MFG + G+ + +LI+SSD N G R + F LL L+DEQL KK + + FGT L++ ++N R++ E ++ + GGCNL++ALK V + + +D +++++ SCPDQ + L ++QQ +GR + H +++++ + + Y+ S GN
Sbjct: 1 MFGLIKGNSVGLLIESSDLNSG-PRRLDFLRGLLCLVDEQLCYKKQLFLLSFGTEVHSLWESAKDVNIRLLHETRQWIQELQPQGGCNLLRALKRVLQVQELDSLVIVVSSCPDQTEEALSDYIQQCTIGRTIQIHIIAFDSLGQVI-----YLCACSWGN 155 HSP 3 Score: 84.7297 bits (208), Expect = 2.095e-16 Identity = 63/217 (29.03%), Postives = 104/217 (47.93%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL-------LITLEDPRIQGIYLLTDGKPD 3767
TS +W+KK LK L L ++++ E + L+K V + + + GT K++ L +Y + K Y KR++WL S+R++G + E V +L+D S S + H+ + +L+ L+ EQ+ + + +NIIAF S+I ++ +V P + A W L G + A+ I E+ QGIYL T G PD
Sbjct: 183 TSAEWLKKNGLKAKKLSLYQILAPNAYSLVEEFVPILQKTVSSTLHERAMMQFEWHDGTVKNIHVDPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSNSMHIIHIQHSLRLLLEEQMSNKDL-FNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPD 398 HSP 4 Score: 57.3806 bits (137), Expect = 1.044e-7 Identity = 43/164 (26.22%), Postives = 76/164 (46.34%), Query Frame = 3
Query: 633 GTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDE-------VLLILGSCPDQE 1103
GT N V D ++ +Y+ +L Y KRI W GSR+++G V ++ +L+D S +N +I Q +L LL+EQ+ K NI FG+ + + ++ + +++ GG N++ A++ + ID + L PDQ+
Sbjct: 240 GTVKNIHV-DPPVLREYQRQLAKMARTYEKRIDWLTNGSRRLWGAVCEKRVVLLVDISLSN--SMHIIHIQHSLRLLLEEQMSNKDLFNIIAFGSEITSWKSEMVPPTAENLQRAWKWVLSLNCEGGRNVLGAMRRAVEVNFIDNENQESQGIYLFTSGVPDQD 400
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Xenopus
Match: ENSXETT00000049307.1 (pep primary_assembly:Xenopus_tropicalis_v9.1:2:109671931:109699265:1 gene:ENSXETG00000020946.1 transcript:ENSXETT00000049307.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 149.828 bits (377), Expect = 4.658e-36 Identity = 95/288 (32.99%), Postives = 144/288 (50.00%), Query Frame = 3
Query: 3129 EEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALI----IPLE-----------KYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIR 3947
E++++SK W+ KY LK L + + RH + ++ P + K + AKYC G+ HL T + Y K L + +R++WL S+ +FG I E V IL+DTS SM + + + LI EQL K K+ +N + F+S++ ++ RL E + A W + L +T+T +AL + D + IYLLTDG+PD E +L V N S VPIHTISF+C D AN FL +L+ + GR+H C+ ++R
Sbjct: 349 EDYVSSKQWLIKYGLKAQKLQFYDVFADCAFRHSDGVVDIKTKPEDESMQTDADTKMKLINAKYCDQFVHTQWKDGSVVHLYITKEKWRWYEERMKTVLEQMERRIQWLQQGSRELFGTILEDRVYILIDTSHSMKDKLFLVKEKMFQLIEEQL-KHKLMFNFVKFDSKVEAWKSRLAKVTEDTLQEASCWVKELQVGSSTNTLRALQVAFNDSSTEAIYLLTDGRPDQPAETILAQV-NFQKS----VPIHTISFSCNDVDANSFLYQLSCKTEGRFH--CYTSNLR 628 HSP 2 Score: 106.686 bits (265), Expect = 1.471e-22 Identity = 77/262 (29.39%), Postives = 129/262 (49.24%), Query Frame = 3
Query: 1938 YEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWF-------RESGIIESDDIRVLMAEI 2702
Y + +W DGSV +++ + Y++ + ++ ME+RI WL GSR +FGTI+E +V +++D S S L + + + LI++QLK K FN + F + + ++K+ L V E LQ++ W++ L S N L AL+ F ++ + IYL T G PDQ E ++A + + IHT+ F+ +D D + + L+ T+GRFH + + S+DI +L EI
Sbjct: 412 YCDQFVHTQWKDGSVVHLYITKEKWRWYEERMKTVLEQMERRIQWLQQGSRELFGTILEDRVYILIDTSHSMKDKLFLVKEKMFQLIEEQLKHKLMFNFVKFDSKVEAWKSRLAKVTEDTLQEASCWVKELQVGSSTNTLRALQVAF-------NDSSTEAIYLLTDGRPDQPAETILAQVN---FQKSVPIHTISFSCNDVDANS---------------FLYQLSCKTEGRFHCYTSNLRDPKAPQPFVSEDICLLQNEI 648 HSP 3 Score: 76.6406 bits (187), Expect = 2.337e-13 Identity = 52/226 (23.01%), Postives = 108/226 (47.79%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELM----YTSNDIDLLLLEIERTQEVLEKIE 1346
YE ++ +E +RI+W QGSR++FG + ++ +LID+S + ++ ++ + L++EQL K N F + + + ++E + N ++AL+ + S + + L+ PDQ A+ ++ Q+ + +P H +S+ + +S L ++ + G +H Y+S + + S DI LL EI++ + L+K++
Sbjct: 439 YEERMKTVLEQMERRIQWLQQGSRELFGTILEDRVYILIDTSHSMK--DKLFLVKEKMFQLIEEQLKHKLMFNFVKFDSKVEAWKSRLAKVTEDTLQEASCWVKELQVGSSTNTLRALQVAFNDSSTEAIYLLTDGRPDQPAETIL---AQVNFQKSVPIHTISFSCNDVDANSFLYQLSCKTEGRFHCYTSNLRDPKAPQPFVSEDICLLQNEIKQGKADLQKVQ 659 HSP 4 Score: 74.7146 bits (182), Expect = 8.812e-13 Identity = 75/325 (23.08%), Postives = 144/325 (44.31%), Query Frame = 3
Query: 3123 DKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGW---TEHLVA----CGNTDTTKALLITLEDPRIQGIYLLT-DGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDY--DIRMFSQRVIEQSKTTALP-------QNDIDTKQDRTTVAADL 4046
D +S W+K + LK L +++++S + +E + L + V ++Y GLFP N G +L + + + Y +RL WL S+ IFGVI E V +L+ G ++ E+ + L+ + ++NII + ++ ++ V + S +A+ W T+H C ++ALL +++ +Y T + + +++LK V + + P+H +S+N + E FLK ++ ++GR CH Y D + + + + ALP ++D +QD + +L
Sbjct: 6 DAHTLTSSSKWLKTHGLKKKKLSMMKILSQLGFQQKEDYVSKLGRPVSSRYSQGLFPQYNFAGKIYNLTAKKEQFLQKVESLTNTIELYNERLGWLTSGSRAIFGVIQENSVIFVLE-CGCLSKEQFEMYQDAFCLLIREQVAHISNFNIIWVSQVPEKWHDKQVHVSQDSIETAVEWVHNTQHPPVENPECAANALSEALLY-----QVEAVYYFTAEDISEVKKQLLLKYVSD------SPCPVHFVSYNPQKEETITFLKEISHQTSGR----CHVYKADCKQLNTALKLKEVNAALPTSTTEKTHEELDLQQDEFLMMKEL 314 HSP 5 Score: 62.003 bits (149), Expect = 8.622e-9 Identity = 59/264 (22.35%), Postives = 119/264 (45.08%), Query Frame = 3
Query: 1863 ILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTS-GVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR 2651
ILS+ ++ K +++ +GR V+S + Q + G + N+ A Q + + L ++L +R+ WL++GSR IFG I E VI +L+ + + + +LI++Q+ FNII S + V++ +++ + W+ + N A + E + V + +Y FT+ + + + + L+ Y+ + + +H V +N P + IT ++ ++H T GR H ++
Sbjct: 32 ILSQLGFQQKEDYVSKLGRPVSSRYSQGLFPQYNFA-GKIYNLTAKKEQFLQKVESLTNTIELYNERLGWLTSGSRAIFGVIQENSVIFVLECGCLSKEQFEMYQDAFCLLIREQVAHISNFNIIWVSQVPEKWHDKQVHVSQDSIETAVEWVHNTQHPPVENPECAANALSEALLYQV-----EAVYYFTAEDISEVKKQLLLKYVSD----SPCPVHFVSYN-----------PQKEETIT----FLKEISHQTSGRCHVYK 270
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Mouse
Match: Vwa3a (von Willebrand factor A domain containing 3A [Source:MGI Symbol;Acc:MGI:3041229]) HSP 1 Score: 493.812 bits (1270), Expect = 1.945e-152 Identity = 301/828 (36.35%), Postives = 451/828 (54.47%), Query Frame = 3
Query: 1710 FSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVEL--CRRNSSDNMVALMPPRQTSLSKARLKY---LSDKTEENLKIPKTLAYKSDIDPRKSIT-----NSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFR 4163
F+S + KP K + +L + S + G+K ++ +L+ NA+ EF+P + + V ++++EKAM+Q EW DG+V+N+H D LFEYQK LG+ V++ E R+ WLS SRRI+GT+ +R+V+++LD+S++N Y++HI SL++L+++QL KD FNIIAF +TI S++ + V+ NLQ +W W L C GSRN+LGAL+ E + +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+ YA+ T TA + + + +GRFHWF E+GI ESDDI +++EI+ A+ YS++ ++ K +HS+K ++ A+E R PP+ T+ S AR+ L +T LK K + P K T +KP RP + FYTE NS G VY+ Y Q RR +P K+ +S++W LK + L+L + + GP CR+++++ P A++C LFP + + G +H+Q+T+ E+ Y +K Y++RL WL+ S+R+FG I E +V ILLDTSGSM PH+ + L LIWEQL K +N+++F ++ +++ LV E++CH A+ W HL A G+T AL +QG+YLLTDGKPD S ++L VQ+ R KV HTIS D +A EFL+ LA +S GRYH D + S L ++D P LP EGDDL LA+E R L + FR
Sbjct: 355 FTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLKAK-------KLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTP-PACYASRTDTATAYKEITQAARGRFHWFGETGIYESDDINAIVSEIEKALNYSQKCAFLVASLK-----NHSEK--ELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKEGTVEQRMKTKPRTRPKL-FLFYTEAGNSVGSVYKRYT-QGKSIRRINSSIQLPRKDTVCSSQEWTATCRLKRLKLELSKCL-GPNCRYQKSVRGP----ALAEHCT-LFPSIEINGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKV--HTISLTSADRTATEFLRELASLSGGRYHCPVSDKAL----------SGIQGLLTRGFIKERD---------------PKLPLFEGDDLRLLAEEFTRARNLLKQAQVFR 1132 HSP 2 Score: 196.052 bits (497), Expect = 3.636e-50 Identity = 117/354 (33.05%), Postives = 191/354 (53.95%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT +NQ DLL++Q + + SEDWL H+L +LT+ DLIS+G + E A + + + ++ +L IE+Y +R++W + S+K FG + GS++ +LIDSS + G + FQ++L L+DEQL K+ + + FG L+ D M ++ ++E+K T+ G NL+QALK V K ++ +++IL SCPDQ ++ L F+QQ LGR + H +Y+ S++LK + G YH YS +E +YTS D+ L +E + Q +L +++ + S I +I+ E+ P + LPKP PL + P + +TS+EW
Sbjct: 38 VTHVNQTQDLLQLQGRETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTV----ELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSG-SQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSPESE--LYTSRDVVELQVETHKAQGLLSQVQALCHNNPCEELSCMIKEISIEIAKGPFTSLLPKPPKHEAPLTIKFPDLD-KTSAEW 383 HSP 3 Score: 134.42 bits (337), Expect = 4.499e-31 Identity = 171/769 (22.24%), Postives = 318/769 (41.35%), Query Frame = 3
Query: 519 EQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----------------------RPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT----KEKSIDE---VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPK--------------FEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTRDANISRKSIQG---RRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFH 2642
+++S +WLK + L A +L++ +++ NP + + GT N V D ++ +Y+ +L A+++Y R++W SR+++G V ++ +L+D S N + +I Q +L LL+EQL K NI FG+ + + + ++ ++ + G N++ AL+ K+K+ E + L G PDQ+ +L +V + G DL + C+ Y + + + ++ K I + G +H + E +Y S+DI+ ++ EIE+ +K + + N +EL++ ++ P+ + + P K PK + TSS K T+ + P + P +F ++ ++ QG RR +S+I P K T+ + +E++ +T + +++ L N KS P++ T ++ I +G VR++ L ++ Y + + + QR+ WL +GSRR+FGTI+ER V ++LD S S +L I L +LI +Q K +FN+++F+ + ++ L E + W+ L GS ++L AL F S + QG+YL T G PD ++ ++ +K+HT+ D + E +R LA + GR+H
Sbjct: 377 DKTSAEWLKINGLKAKKLSLYQVLAPNAF-NPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHV-DPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMY--IIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFG---ETGIYESDDINAIVSEIEKALNYSQKCAFL--------VASLKNHSEKELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKE---GTVEQRMKTKPRTRP-----KLFLFYTEAGNSVGSVYKRYTQGKSIRRINSSIQLPRKD------TVCSSQEWT-----------ATCRLKRLKLELSKCLGPNCRYQKSVRGPALAEHCT--LFPSIEI-----NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAF-----SFQD--VQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTAT---------------EFLRELASLSGGRYH 1076 HSP 4 Score: 75.0998 bits (183), Expect = 6.272e-13 Identity = 71/280 (25.36%), Postives = 131/280 (46.79%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-ESGIIESDDIRVLMAEIDLAVEYSRRTQQIIND 2750
++ + + + +++E + +V VH + ++ L + ++L +QR+ WL+ S++ FG I +V L++D S +S+ L LI +QL K+K +++F TI+ V+ + LQ+ W+++L GS NLL ALK VF H + + + S PDQ E L +I++ LG + IH + DD+ +PS +++ L + G +H + ES + S D+ L E A + Q + ++
Sbjct: 76 KLTLADLISQGTVELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVF------AHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDH------VPS---------AVLKNLTDALGGYYHCYSPESELYTSRDVVELQVETHKAQGLLSQVQALCHN 333 HSP 5 Score: 67.3958 bits (163), Expect = 1.332e-10 Identity = 68/281 (24.20%), Postives = 120/281 (42.70%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLD----TSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQR-VIE 3971
S+DW+ +SLK L L L+S + VE + C P V+ +T ++ + + Y +R+ WL +SK+ FG+I + V +L+D +SGS T E +L LI EQL ++ Y +++F I + S+ W + L G+++ +AL + + ++ PD +E + +Q S+ V IH ++ C+D + LK L G YH C+ + +++ R V+E
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS--------------QGTVELEDCNNAVPKVH---------FTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQT---KEFQNDLTGLIDEQLSLKEKLY-VLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQ--STLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYH--CYSPESELYTSRDVVE 312
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Mouse
Match: Vwa3a (von Willebrand factor A domain containing 3A [Source:MGI Symbol;Acc:MGI:3041229]) HSP 1 Score: 493.812 bits (1270), Expect = 1.945e-152 Identity = 301/828 (36.35%), Postives = 451/828 (54.47%), Query Frame = 3
Query: 1710 FSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVEL--CRRNSSDNMVALMPPRQTSLSKARLKY---LSDKTEENLKIPKTLAYKSDIDPRKSIT-----NSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFR 4163
F+S + KP K + +L + S + G+K ++ +L+ NA+ EF+P + + V ++++EKAM+Q EW DG+V+N+H D LFEYQK LG+ V++ E R+ WLS SRRI+GT+ +R+V+++LD+S++N Y++HI SL++L+++QL KD FNIIAF +TI S++ + V+ NLQ +W W L C GSRN+LGAL+ E + +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+ YA+ T TA + + + +GRFHWF E+GI ESDDI +++EI+ A+ YS++ ++ K +HS+K ++ A+E R PP+ T+ S AR+ L +T LK K + P K T +KP RP + FYTE NS G VY+ Y Q RR +P K+ +S++W LK + L+L + + GP CR+++++ P A++C LFP + + G +H+Q+T+ E+ Y +K Y++RL WL+ S+R+FG I E +V ILLDTSGSM PH+ + L LIWEQL K +N+++F ++ +++ LV E++CH A+ W HL A G+T AL +QG+YLLTDGKPD S ++L VQ+ R KV HTIS D +A EFL+ LA +S GRYH D + S L ++D P LP EGDDL LA+E R L + FR
Sbjct: 355 FTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLKAK-------KLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTP-PACYASRTDTATAYKEITQAARGRFHWFGETGIYESDDINAIVSEIEKALNYSQKCAFLVASLK-----NHSEK--ELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKEGTVEQRMKTKPRTRPKL-FLFYTEAGNSVGSVYKRYT-QGKSIRRINSSIQLPRKDTVCSSQEWTATCRLKRLKLELSKCL-GPNCRYQKSVRGP----ALAEHCT-LFPSIEINGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKV--HTISLTSADRTATEFLRELASLSGGRYHCPVSDKAL----------SGIQGLLTRGFIKERD---------------PKLPLFEGDDLRLLAEEFTRARNLLKQAQVFR 1132 HSP 2 Score: 196.052 bits (497), Expect = 3.636e-50 Identity = 117/354 (33.05%), Postives = 191/354 (53.95%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT +NQ DLL++Q + + SEDWL H+L +LT+ DLIS+G + E A + + + ++ +L IE+Y +R++W + S+K FG + GS++ +LIDSS + G + FQ++L L+DEQL K+ + + FG L+ D M ++ ++E+K T+ G NL+QALK V K ++ +++IL SCPDQ ++ L F+QQ LGR + H +Y+ S++LK + G YH YS +E +YTS D+ L +E + Q +L +++ + S I +I+ E+ P + LPKP PL + P + +TS+EW
Sbjct: 38 VTHVNQTQDLLQLQGRETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTV----ELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSG-SQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSPESE--LYTSRDVVELQVETHKAQGLLSQVQALCHNNPCEELSCMIKEISIEIAKGPFTSLLPKPPKHEAPLTIKFPDLD-KTSAEW 383 HSP 3 Score: 134.42 bits (337), Expect = 4.499e-31 Identity = 171/769 (22.24%), Postives = 318/769 (41.35%), Query Frame = 3
Query: 519 EQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----------------------RPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT----KEKSIDE---VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPK--------------FEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTRDANISRKSIQG---RRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFH 2642
+++S +WLK + L A +L++ +++ NP + + GT N V D ++ +Y+ +L A+++Y R++W SR+++G V ++ +L+D S N + +I Q +L LL+EQL K NI FG+ + + + ++ ++ + G N++ AL+ K+K+ E + L G PDQ+ +L +V + G DL + C+ Y + + + ++ K I + G +H + E +Y S+DI+ ++ EIE+ +K + + N +EL++ ++ P+ + + P K PK + TSS K T+ + P + P +F ++ ++ QG RR +S+I P K T+ + +E++ +T + +++ L N KS P++ T ++ I +G VR++ L ++ Y + + + QR+ WL +GSRR+FGTI+ER V ++LD S S +L I L +LI +Q K +FN+++F+ + ++ L E + W+ L GS ++L AL F S + QG+YL T G PD ++ ++ +K+HT+ D + E +R LA + GR+H
Sbjct: 377 DKTSAEWLKINGLKAKKLSLYQVLAPNAF-NPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHV-DPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMY--IIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFG---ETGIYESDDINAIVSEIEKALNYSQKCAFL--------VASLKNHSEKELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKE---GTVEQRMKTKPRTRP-----KLFLFYTEAGNSVGSVYKRYTQGKSIRRINSSIQLPRKD------TVCSSQEWT-----------ATCRLKRLKLELSKCLGPNCRYQKSVRGPALAEHCT--LFPSIEI-----NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAF-----SFQD--VQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTAT---------------EFLRELASLSGGRYH 1076 HSP 4 Score: 75.0998 bits (183), Expect = 6.272e-13 Identity = 71/280 (25.36%), Postives = 131/280 (46.79%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-ESGIIESDDIRVLMAEIDLAVEYSRRTQQIIND 2750
++ + + + +++E + +V VH + ++ L + ++L +QR+ WL+ S++ FG I +V L++D S +S+ L LI +QL K+K +++F TI+ V+ + LQ+ W+++L GS NLL ALK VF H + + + S PDQ E L +I++ LG + IH + DD+ +PS +++ L + G +H + ES + S D+ L E A + Q + ++
Sbjct: 76 KLTLADLISQGTVELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVF------AHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDH------VPS---------AVLKNLTDALGGYYHCYSPESELYTSRDVVELQVETHKAQGLLSQVQALCHN 333 HSP 5 Score: 67.3958 bits (163), Expect = 1.332e-10 Identity = 68/281 (24.20%), Postives = 120/281 (42.70%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLD----TSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQR-VIE 3971
S+DW+ +SLK L L L+S + VE + C P V+ +T ++ + + Y +R+ WL +SK+ FG+I + V +L+D +SGS T E +L LI EQL ++ Y +++F I + S+ W + L G+++ +AL + + ++ PD +E + +Q S+ V IH ++ C+D + LK L G YH C+ + +++ R V+E
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS--------------QGTVELEDCNNAVPKVH---------FTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQT---KEFQNDLTGLIDEQLSLKEKLY-VLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQ--STLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYH--CYSPESELYTSRDVVE 312
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Mouse
Match: Vwa3a (von Willebrand factor A domain containing 3A [Source:MGI Symbol;Acc:MGI:3041229]) HSP 1 Score: 493.812 bits (1270), Expect = 1.945e-152 Identity = 301/828 (36.35%), Postives = 451/828 (54.47%), Query Frame = 3
Query: 1710 FSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVEL--CRRNSSDNMVALMPPRQTSLSKARLKY---LSDKTEENLKIPKTLAYKSDIDPRKSIT-----NSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFR 4163
F+S + KP K + +L + S + G+K ++ +L+ NA+ EF+P + + V ++++EKAM+Q EW DG+V+N+H D LFEYQK LG+ V++ E R+ WLS SRRI+GT+ +R+V+++LD+S++N Y++HI SL++L+++QL KD FNIIAF +TI S++ + V+ NLQ +W W L C GSRN+LGAL+ E + +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+ YA+ T TA + + + +GRFHWF E+GI ESDDI +++EI+ A+ YS++ ++ K +HS+K ++ A+E R PP+ T+ S AR+ L +T LK K + P K T +KP RP + FYTE NS G VY+ Y Q RR +P K+ +S++W LK + L+L + + GP CR+++++ P A++C LFP + + G +H+Q+T+ E+ Y +K Y++RL WL+ S+R+FG I E +V ILLDTSGSM PH+ + L LIWEQL K +N+++F ++ +++ LV E++CH A+ W HL A G+T AL +QG+YLLTDGKPD S ++L VQ+ R KV HTIS D +A EFL+ LA +S GRYH D + S L ++D P LP EGDDL LA+E R L + FR
Sbjct: 355 FTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLKAK-------KLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTP-PACYASRTDTATAYKEITQAARGRFHWFGETGIYESDDINAIVSEIEKALNYSQKCAFLVASLK-----NHSEK--ELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKEGTVEQRMKTKPRTRPKL-FLFYTEAGNSVGSVYKRYT-QGKSIRRINSSIQLPRKDTVCSSQEWTATCRLKRLKLELSKCL-GPNCRYQKSVRGP----ALAEHCT-LFPSIEINGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKV--HTISLTSADRTATEFLRELASLSGGRYHCPVSDKAL----------SGIQGLLTRGFIKERD---------------PKLPLFEGDDLRLLAEEFTRARNLLKQAQVFR 1132 HSP 2 Score: 196.052 bits (497), Expect = 3.636e-50 Identity = 117/354 (33.05%), Postives = 191/354 (53.95%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT +NQ DLL++Q + + SEDWL H+L +LT+ DLIS+G + E A + + + ++ +L IE+Y +R++W + S+K FG + GS++ +LIDSS + G + FQ++L L+DEQL K+ + + FG L+ D M ++ ++E+K T+ G NL+QALK V K ++ +++IL SCPDQ ++ L F+QQ LGR + H +Y+ S++LK + G YH YS +E +YTS D+ L +E + Q +L +++ + S I +I+ E+ P + LPKP PL + P + +TS+EW
Sbjct: 38 VTHVNQTQDLLQLQGRETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTV----ELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSG-SQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSPESE--LYTSRDVVELQVETHKAQGLLSQVQALCHNNPCEELSCMIKEISIEIAKGPFTSLLPKPPKHEAPLTIKFPDLD-KTSAEW 383 HSP 3 Score: 134.42 bits (337), Expect = 4.499e-31 Identity = 171/769 (22.24%), Postives = 318/769 (41.35%), Query Frame = 3
Query: 519 EQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----------------------RPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT----KEKSIDE---VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPK--------------FEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTRDANISRKSIQG---RRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFH 2642
+++S +WLK + L A +L++ +++ NP + + GT N V D ++ +Y+ +L A+++Y R++W SR+++G V ++ +L+D S N + +I Q +L LL+EQL K NI FG+ + + + ++ ++ + G N++ AL+ K+K+ E + L G PDQ+ +L +V + G DL + C+ Y + + + ++ K I + G +H + E +Y S+DI+ ++ EIE+ +K + + N +EL++ ++ P+ + + P K PK + TSS K T+ + P + P +F ++ ++ QG RR +S+I P K T+ + +E++ +T + +++ L N KS P++ T ++ I +G VR++ L ++ Y + + + QR+ WL +GSRR+FGTI+ER V ++LD S S +L I L +LI +Q K +FN+++F+ + ++ L E + W+ L GS ++L AL F S + QG+YL T G PD ++ ++ +K+HT+ D + E +R LA + GR+H
Sbjct: 377 DKTSAEWLKINGLKAKKLSLYQVLAPNAF-NPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHV-DPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMY--IIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFG---ETGIYESDDINAIVSEIEKALNYSQKCAFL--------VASLKNHSEKELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKE---GTVEQRMKTKPRTRP-----KLFLFYTEAGNSVGSVYKRYTQGKSIRRINSSIQLPRKD------TVCSSQEWT-----------ATCRLKRLKLELSKCLGPNCRYQKSVRGPALAEHCT--LFPSIEI-----NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAF-----SFQD--VQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTAT---------------EFLRELASLSGGRYH 1076 HSP 4 Score: 75.0998 bits (183), Expect = 6.272e-13 Identity = 71/280 (25.36%), Postives = 131/280 (46.79%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-ESGIIESDDIRVLMAEIDLAVEYSRRTQQIIND 2750
++ + + + +++E + +V VH + ++ L + ++L +QR+ WL+ S++ FG I +V L++D S +S+ L LI +QL K+K +++F TI+ V+ + LQ+ W+++L GS NLL ALK VF H + + + S PDQ E L +I++ LG + IH + DD+ +PS +++ L + G +H + ES + S D+ L E A + Q + ++
Sbjct: 76 KLTLADLISQGTVELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVF------AHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDH------VPS---------AVLKNLTDALGGYYHCYSPESELYTSRDVVELQVETHKAQGLLSQVQALCHN 333 HSP 5 Score: 67.3958 bits (163), Expect = 1.332e-10 Identity = 68/281 (24.20%), Postives = 120/281 (42.70%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLD----TSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQR-VIE 3971
S+DW+ +SLK L L L+S + VE + C P V+ +T ++ + + Y +R+ WL +SK+ FG+I + V +L+D +SGS T E +L LI EQL ++ Y +++F I + S+ W + L G+++ +AL + + ++ PD +E + +Q S+ V IH ++ C+D + LK L G YH C+ + +++ R V+E
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS--------------QGTVELEDCNNAVPKVH---------FTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQT---KEFQNDLTGLIDEQLSLKEKLY-VLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQ--STLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYH--CYSPESELYTSRDVVE 312
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Mouse
Match: Vwa3a (von Willebrand factor A domain containing 3A [Source:MGI Symbol;Acc:MGI:3041229]) HSP 1 Score: 195.282 bits (495), Expect = 5.814e-52 Identity = 117/354 (33.05%), Postives = 191/354 (53.95%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT +NQ DLL++Q + + SEDWL H+L +LT+ DLIS+G + E A + + + ++ +L IE+Y +R++W + S+K FG + GS++ +LIDSS + G + FQ++L L+DEQL K+ + + FG L+ D M ++ ++E+K T+ G NL+QALK V K ++ +++IL SCPDQ ++ L F+QQ LGR + H +Y+ S++LK + G YH YS +E +YTS D+ L +E + Q +L +++ + S I +I+ E+ P + LPKP PL + P + +TS+EW
Sbjct: 38 VTHVNQTQDLLQLQGRETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTV----ELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSG-SQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSPESE--LYTSRDVVELQVETHKAQGLLSQVQALCHNNPCEELSCMIKEISIEIAKGPFTSLLPKPPKHEAPLTIKFPDLD-KTSAEW 383 HSP 2 Score: 194.897 bits (494), Expect = 8.275e-52 Identity = 102/250 (40.80%), Postives = 158/250 (63.20%), Query Frame = 3
Query: 1710 FSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQI 2459
F+S + KP K + +L + S + G+K ++ +L+ NA+ EF+P + + V ++++EKAM+Q EW DG+V+N+H D LFEYQK LG+ V++ E R+ WLS SRRI+GT+ +R+V+++LD+S++N Y++HI SL++L+++QL KD FNIIAF +TI S++ + V+ NLQ +W W L C GSRN+LGAL+ E + +QGIYLFT G+PDQ +
Sbjct: 355 FTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLKAK-------KLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDV 597 HSP 3 Score: 82.0333 bits (201), Expect = 3.038e-15 Identity = 66/218 (30.28%), Postives = 103/218 (47.25%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLE-------DPRIQGIYLLTDGKPDN 3770
TS +W+K LK L L ++++ E + L+K V A + + GT K++ L +Y + KA+ Y RL+WL ++S+RI+G + + V ILLD S + + ++ + +L+ L+ EQL K +NIIAF S I +R +V + A W L G+ + AL +E QGIYL T G PD
Sbjct: 379 TSAEWLKINGLKAKKLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQL-SNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQ 595 HSP 4 Score: 73.559 bits (179), Expect = 1.141e-12 Identity = 69/263 (26.24%), Postives = 125/263 (47.53%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-ESGIIESDDIRVLMAE 2699
++ + + + +++E + +V VH + ++ L + ++L +QR+ WL+ S++ FG I +V L++D S +S+ L LI +QL K+K +++F TI+ V+ + LQ+ W+++L GS NLL ALK VF H + + + S PDQ E L +I++ LG + IH + DD+ +PS +++ L + G +H + ES + S D+ L E
Sbjct: 76 KLTLADLISQGTVELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVF------AHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDH------VPS---------AVLKNLTDALGGYYHCYSPESELYTSRDVVELQVE 316 HSP 5 Score: 68.5514 bits (166), Expect = 4.606e-11 Identity = 68/281 (24.20%), Postives = 120/281 (42.70%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLD----TSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQR-VIE 3971
S+DW+ +SLK L L L+S + VE + C P V+ +T ++ + + Y +R+ WL +SK+ FG+I + V +L+D +SGS T E +L LI EQL ++ Y +++F I + S+ W + L G+++ +AL + + ++ PD +E + +Q S+ V IH ++ C+D + LK L G YH C+ + +++ R V+E
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS--------------QGTVELEDCNNAVPKVH---------FTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQT---KEFQNDLTGLIDEQLSLKEKLY-VLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQ--STLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYH--CYSPESELYTSRDVVE 312 HSP 6 Score: 56.6102 bits (135), Expect = 1.938e-7 Identity = 54/234 (23.08%), Postives = 106/234 (45.30%), Query Frame = 3
Query: 519 EQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----------------------RPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT----KEKSIDE---VLLILGSCPDQEAKMLMYFVQQ 1133
+++S +WLK + L A +L++ +++ NP + + GT N V D ++ +Y+ +L A+++Y R++W SR+++G V ++ +L+D S N + +I Q +L LL+EQL K NI FG+ + + + ++ ++ + G N++ AL+ K+K+ E + L G PDQ+ + V+
Sbjct: 377 DKTSAEWLKINGLKAKKLSLYQVLAPNAF-NPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHV-DPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMY--IIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVTWTEHTVEH 606
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Mouse
Match: Vwa3b (von Willebrand factor A domain containing 3B [Source:MGI Symbol;Acc:MGI:1918103]) HSP 1 Score: 153.68 bits (387), Expect = 1.231e-37 Identity = 174/700 (24.86%), Postives = 298/700 (42.57%), Query Frame = 3
Query: 1857 ENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQV-EWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLN--------CSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAE-IDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDII---KNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRY 3917
+ ILS+ + +++ S+ R+V S + Q+ DG + N+ A + ++ L + V+ +QR+ WL++GSR+IFG I+E++V ++LD ++ L +LK+++Q+Q+ +FN+I S ++ +V E ++ + SW+ + SG LL A K + + IY F G Q+ + L+ VL + TV FN A +T ++ L+ T RFH F E E ++ E +D ++ ++ R K + PP + ED+ + E CR A+++ L DK A +SD+ P + S+P SK + Q + G+ K + +T D + S ++ ++ + + PE + +K + AKYC+ I G+ H+ T + Y AL +R++WL S +FG + +L+DTS SM + + + I EQL + K +N + F+ Q +RE+L +E + A W + +T+T AL I D Q IYLLTDG+PD E+V+ +V+ + +PI ISF+ DE ANEFLK LA ++ G +
Sbjct: 26 KQILSQIGFPQSEDYVTSLRRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITRFNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGK-----------DKTIEAIYYFVVGDVPQEFQKLLL---TGVLEIPYPVCTVSFN---------------ARGEETIAFLKDLSTKTHSRFHAFAER--TECEEFSAFSTEGVDGSMTWNSRK------LKGRLPPGAGVR-EDVFLIWREMEEACR------------------ILAQVRSLVDK-----------APQSDVSP--ADCKSRPA--------------ESKENAEDTWESQKWLQKYGL-------KAQKLTFYDVLAHCSFRHAD-GVVDIKAKPENESVQTSADTNKKTIHAKYCSRFIHIPWKDGSLVHVNITKEKYKWYRERIHTALAMIQRRIKWLQNGSHILFGKARGECIYVLIDTSCSMKSRLNLVKDKIIQFIQEQL-RYKSKFNFVTFDGQAIAWREKLAEVNEDNLKQAQSWIRGIKVGSSTNTLNALKIAFADEETQVIYLLTDGRPDQPPEMVMDHVKLFQN-----IPICAISFSYNDEVANEFLKELAALTGGEF 628 HSP 2 Score: 91.2781 bits (225), Expect = 5.453e-18 Identity = 78/292 (26.71%), Postives = 129/292 (44.18%), Query Frame = 3
Query: 3138 ITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALI------------RYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQ--LFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLV----ACGNTDTTKALLITLEDPRIQGIYLLTDGK-PDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFS 3956
++S+ W++ + LK+ L L +++S E + L + V ++Y GLFP + YT + Y++ AK LI Y +R++WL S++IFGVI E V I+LD + + LK ++ EQ L R +N+I +++ +++E + E S +AI W E + ALL +D I+ IY G P +++L V I P+ T+SFN E FLK L+ ++ R+H + FS
Sbjct: 7 LSSERWLQLHGLKSKKLTLKQILSQIGFPQSEDYVTSLRRLVASRYADGLFPQI----------YTAEDGRLYNLTAKTELICQFVDYLTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCRDALKMVLQEQVALITR---FNMIWVSAEPVKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSGLDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEI------PYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAERTECEEFS 279 HSP 3 Score: 77.7962 bits (190), Expect = 8.094e-14 Identity = 56/224 (25.00%), Postives = 105/224 (46.88%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSN--DIDLLLLEIERTQEVLEKIE 1346
Y ++H A+ M +RIKW GS +FG G + VLID+S + R+ +D ++ + EQL K N F + +N +++ + + N + ALK ++ + L+ PDQ +M+M V+ L +++P +S+ E + LK +A ++ G + Y+ ++ + + D++LLL E+E+ LEK++
Sbjct: 447 YRERIHTALAMIQRRIKWLQNGSHILFGKARGECIYVLIDTSCSMK--SRLNLVKDKIIQFIQEQLRYKSKFNFVTFDGQAIAWREKLAEVNEDNLKQAQSWIRGIKVGSSTNTLNALKIAFADEETQVIYLLTDGRPDQPPEMVMDHVK---LFQNIPICAISFSYNDEVANEFLKELAALTGGEFRAYNFGCKDPIQDTQDEDLNLLLQEMEQGHSDLEKMQ 665 HSP 4 Score: 66.2402 bits (160), Expect = 2.863e-10 Identity = 65/283 (22.97%), Postives = 123/283 (43.46%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDE------------------------QTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDA---NLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNL--------NCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEV-LLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTE 1265
SSE WL+ H L + +LT++ ++S+ +G P+ ++ + G YN + I +Y L A+E Y +R+ W GSR++FG + ++ +++D D L R D L +L EQ+ N+ + +Q++ L IE++ + + G + AL K+K+I+ + ++G P + K+L+ V ++ P VS+ + EE + LK ++T +H +H ++ TE
Sbjct: 8 SSERWLQLHGLKSKKLTLKQILSQ--IGFPQSEDYVTSLRRLVASRYADGLFPQIYTAEDGRLYNLTAKTELICQFVDY-LTQAVESYKQRMDWLTSGSRQIFGVILEQRVTIVLDFGDVLMEELNLCR-----DALKMVLQEQVALITRFNMIWVSAEP-VKWQEYAILVTEHSIAAAISWIEKMTFEPKPVREVSG---LDALLEAGKDKTIEAIYYFVVGDVPQEFQKLLLTGVLEI----PYPVCTVSFNARGEETIAFLKDLSTKTHSRFHAFAERTE 274
BLAST of von Willebrand factor A domain-containing protein 3A vs. UniProt/SwissProt
Match: sp|Q3UVV9|VWA3A_MOUSE (von Willebrand factor A domain-containing protein 3A OS=Mus musculus OX=10090 GN=Vwa3a PE=2 SV=1) HSP 1 Score: 493.812 bits (1270), Expect = 1.360e-151 Identity = 301/828 (36.35%), Postives = 451/828 (54.47%), Query Frame = 3
Query: 1710 FSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVEL--CRRNSSDNMVALMPPRQTSLSKARLKY---LSDKTEENLKIPKTLAYKSDIDPRKSIT-----NSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFR 4163
F+S + KP K + +L + S + G+K ++ +L+ NA+ EF+P + + V ++++EKAM+Q EW DG+V+N+H D LFEYQK LG+ V++ E R+ WLS SRRI+GT+ +R+V+++LD+S++N Y++HI SL++L+++QL KD FNIIAF +TI S++ + V+ NLQ +W W L C GSRN+LGAL+ E + +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+ YA+ T TA + + + +GRFHWF E+GI ESDDI +++EI+ A+ YS++ ++ K +HS+K ++ A+E R PP+ T+ S AR+ L +T LK K + P K T +KP RP + FYTE NS G VY+ Y Q RR +P K+ +S++W LK + L+L + + GP CR+++++ P A++C LFP + + G +H+Q+T+ E+ Y +K Y++RL WL+ S+R+FG I E +V ILLDTSGSM PH+ + L LIWEQL K +N+++F ++ +++ LV E++CH A+ W HL A G+T AL +QG+YLLTDGKPD S ++L VQ+ R KV HTIS D +A EFL+ LA +S GRYH D + S L ++D P LP EGDDL LA+E R L + FR
Sbjct: 355 FTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLKAK-------KLSLYQVLAPNAFNPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMYIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTP-PACYASRTDTATAYKEITQAARGRFHWFGETGIYESDDINAIVSEIEKALNYSQKCAFLVASLK-----NHSEK--ELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKEGTVEQRMKTKPRTRPKL-FLFYTEAGNSVGSVYKRYT-QGKSIRRINSSIQLPRKDTVCSSQEWTATCRLKRLKLELSKCL-GPNCRYQKSVRGP----ALAEHCT-LFPSIEINGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAFSFQDVQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKV--HTISLTSADRTATEFLRELASLSGGRYHCPVSDKAL----------SGIQGLLTRGFIKERD---------------PKLPLFEGDDLRLLAEEFTRARNLLKQAQVFR 1132 HSP 2 Score: 196.052 bits (497), Expect = 2.543e-49 Identity = 117/354 (33.05%), Postives = 191/354 (53.95%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT +NQ DLL++Q + + SEDWL H+L +LT+ DLIS+G + E A + + + ++ +L IE+Y +R++W + S+K FG + GS++ +LIDSS + G + FQ++L L+DEQL K+ + + FG L+ D M ++ ++E+K T+ G NL+QALK V K ++ +++IL SCPDQ ++ L F+QQ LGR + H +Y+ S++LK + G YH YS +E +YTS D+ L +E + Q +L +++ + S I +I+ E+ P + LPKP PL + P + +TS+EW
Sbjct: 38 VTHVNQTQDLLQLQGRETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTV----ELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSG-SQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYHCYSPESE--LYTSRDVVELQVETHKAQGLLSQVQALCHNNPCEELSCMIKEISIEIAKGPFTSLLPKPPKHEAPLTIKFPDLD-KTSAEW 383 HSP 3 Score: 134.42 bits (337), Expect = 3.147e-30 Identity = 171/769 (22.24%), Postives = 318/769 (41.35%), Query Frame = 3
Query: 519 EQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----------------------RPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT----KEKSIDE---VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPK--------------FEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTRDANISRKSIQG---RRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFH 2642
+++S +WLK + L A +L++ +++ NP + + GT N V D ++ +Y+ +L A+++Y R++W SR+++G V ++ +L+D S N + +I Q +L LL+EQL K NI FG+ + + + ++ ++ + G N++ AL+ K+K+ E + L G PDQ+ +L +V + G DL + C+ Y + + + ++ K I + G +H + E +Y S+DI+ ++ EIE+ +K + + N +EL++ ++ P+ + + P K PK + TSS K T+ + P + P +F ++ ++ QG RR +S+I P K T+ + +E++ +T + +++ L N KS P++ T ++ I +G VR++ L ++ Y + + + QR+ WL +GSRR+FGTI+ER V ++LD S S +L I L +LI +Q K +FN+++F+ + ++ L E + W+ L GS ++L AL F S + QG+YL T G PD ++ ++ +K+HT+ D + E +R LA + GR+H
Sbjct: 377 DKTSAEWLKINGLKAKKLSLYQVLAPNAF-NPVEEFVPILQKTVAATIHEKAMVQFEWHDGTVKNIHV-DPPVLFEYQKQLGKAVQIYEHRLQWLSLTSRRIWGTVCQRRVVILLDVSVTNSMY--IIHIQHSLRLLLEEQLSNKDYFNIIAFGSTIESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKNKHESQGIYLFTGGIPDQDVHILSAYVAEAYGGCDLQLNVCLFYVGEPQMDTTPPACYASRTDTATAYKEITQAARGRFHWFG---ETGIYESDDINAIVSEIEKALNYSQKCAFL--------VASLKNHSEKELQSGALEKDKPRTLKQSQPKKHYPPKPTAPSVARMSIKDGLDGETSSRLKALKCHPVNAAAQPEKE---GTVEQRMKTKPRTRP-----KLFLFYTEAGNSVGSVYKRYTQGKSIRRINSSIQLPRKD------TVCSSQEWT-----------ATCRLKRLKLELSKCLGPNCRYQKSVRGPALAEHCT--LFPSIEI-----NGVVRHIQWTLWEMETYITCMEKVTRCYVQRLHWLLSGSRRLFGTILERNVCILLDTSGSMGPHLQWIKTELVLLIWEQLRKHCARFNLLSFAEDLQLWQDTLVESTEAACHKAMQWVAHLQAQGSTSVLAALTKAF-----SFQD--VQGLYLLTDGKPDTSCSLILNTVQSFQKERGVKVHTISLTSADRTAT---------------EFLRELASLSGGRYH 1076 HSP 4 Score: 75.0998 bits (183), Expect = 4.387e-12 Identity = 71/280 (25.36%), Postives = 131/280 (46.79%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-ESGIIESDDIRVLMAEIDLAVEYSRRTQQIIND 2750
++ + + + +++E + +V VH + ++ L + ++L +QR+ WL+ S++ FG I +V L++D S +S+ L LI +QL K+K +++F TI+ V+ + LQ+ W+++L GS NLL ALK VF H + + + S PDQ E L +I++ LG + IH + DD+ +PS +++ L + G +H + ES + S D+ L E A + Q + ++
Sbjct: 76 KLTLADLISQGTVELEDCNNAVPKVHFTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQTKEFQNDLTGLIDEQLSLKEKLYVLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVF------AHKELNSLVIILRS-CPDQPSEFLSDFIQQSTLGRSVFIHVTTYKCDDH------VPS---------AVLKNLTDALGGYYHCYSPESELYTSRDVVELQVETHKAQGLLSQVQALCHN 333 HSP 5 Score: 67.3958 bits (163), Expect = 9.314e-10 Identity = 68/281 (24.20%), Postives = 120/281 (42.70%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLD----TSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQR-VIE 3971
S+DW+ +SLK L L L+S + VE + C P V+ +T ++ + + Y +R+ WL +SK+ FG+I + V +L+D +SGS T E +L LI EQL ++ Y +++F I + S+ W + L G+++ +AL + + ++ PD +E + +Q S+ V IH ++ C+D + LK L G YH C+ + +++ R V+E
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS--------------QGTVELEDCNNAVPKVH---------FTTQTIHHFKSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGSQT---KEFQNDLTGLIDEQLSLKEKLY-VLSFGVTINPLWPDPMEVSTSTLQELKLWVKTLQPEGSSNLLQALKKVFAHKELNSLVIILRSCPDQPSEFLSDFIQQ--STLGRSVFIHVTTYKCDDHVPSAVLKNLTDALGGYYH--CYSPESELYTSRDVVE 312
BLAST of von Willebrand factor A domain-containing protein 3A vs. UniProt/SwissProt
Match: sp|A6NCI4|VWA3A_HUMAN (von Willebrand factor A domain-containing protein 3A OS=Homo sapiens OX=9606 GN=VWA3A PE=2 SV=3) HSP 1 Score: 488.419 bits (1256), Expect = 3.831e-149 Identity = 292/798 (36.59%), Postives = 446/798 (55.89%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKK---NEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSIT--NSKPPYRPVIQS--------------AFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLS---IDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQK 4187
+L+ NA+ EF+P + + V+S+++EKAMIQ EW DG+V+N+H D L++YQ+ L +++ E+RI WLS SRRI+GT+ E++V+++LD+S +N Y++HI SL++L+++QL KD FN+IAF +TI S++ + V+ NLQ +W W +L C GSRN+L AL+ E +QGIYLFT G+PDQ + L AY+ E G D++++ LF V + + TP P+RYA+ T TA + + + GRFHWF ++GI ESDDI +M+E++ A+ YS++ ++ K +HS K + + K + + S L PPR T AR+ D E K+L ++ + R I+ ++P +++ FYTE N G VY+ YP Q RR +P K+ +S++W+ KY LK + L++ R + GP C H+++ ++ AK+C+ +FP V + G +H+Q+T E+ Y +K L RY++RL+WL+ S+R+FG + E+ V ILLDTSGSM P++ ++ L LIWEQL K S+N+++F + +++ LV +++CH A+ W HL A G+T +ALL ++G+YLLTDGKPD S +VL VQ + R KV HTIS NC D +A EFL++LA + GRYH +D + LL+ I+ P LP EGDDL LA+EI R L + FR QLQK
Sbjct: 425 QVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTP-PARYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMASLK-----NHSGKVLGSSALPKEKPKTLQLRSQPK--KLCPPRPTVPLGARMSIKDDPDREKSPPLKSLKWRP-LSSRVGISPAAAQPTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYP-QGRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCM-GPNCTHQKSG----QRSASAKHCS-IFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKV--HTISLNCSDRAAVEFLRKLASFTGGRYH----------------------------CPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQEITKARSFLWQAQSFRS---QLQK 1173 HSP 2 Score: 227.254 bits (578), Expect = 5.050e-59 Identity = 131/375 (34.93%), Postives = 207/375 (55.20%), Query Frame = 3
Query: 390 KVKNFEIIDRNKKYYPPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
K KN + +N N VT +NQ DLLR+Q + S D + SEDWL H+L +LT+ DLIS+G E+ + + I+ +E KL IE+Y +RI+W + S+K FG + G+++++LID S + G + FQ +L+ L+DEQL K+ + + FGTN L+ D M ++ ++E+K T+ GG NL+QALK + K +D ++ I+ SCPDQ +++L ++QQ +GRDL H ++Y + ++LK +A G YH YS E YTS D+D LL EI++ Q +L ++ ++ + + +I+ E+ N P LPKP + PL E P + +TS+EW
Sbjct: 48 KQKNMNGLGQNSD----NGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGT----EVLEEGTNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKE-EFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEH--YTSRDMDELLAEIQKAQSLLSHVQALQHSSPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLD-KTSAEW 410 HSP 3 Score: 140.969 bits (354), Expect = 2.689e-32 Identity = 186/782 (23.79%), Postives = 331/782 (42.33%), Query Frame = 3
Query: 633 GTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK------YVTKEKSIDE-VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRG-------IFSNRASPYINQIAEELKNIPQSENLPKP-------ISF-NDPLKFEVPKFEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESN------FTRDAN----ISRKSIQGR---RFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHW------------FRESGII----------ESDDIRVLMAEIDLAVEYSRRTQQIINDYKEK 2762
GT N V F+ Y+ +L A+ MY +RI+W SR+++G V ++ VL+D S N + +I Q +L LL+EQL K N+ FG+ + + + ++ ++ + G N++ AL+ + K+K + + L G PDQ+ L ++ + G DL + C+ Y + + + ++ K + + G +H + +Y S+DI+ ++ E+E+ +K + + + A P +L++ P+ P+P +S +DP + + P P S +W S S+ +S A PT ++E+ RE+ +T N + +K QGR R SS+I P K D + ++ +++ G+K+ +++ + N KS G+ S+ + VE G VR++ ++ Y + L + ++ QR+ WL +GSRR+FGT++E KV ++LD S S YL + L +LI +Q K D FN+++F+ + S++ L + ++ W+ L GS ++L AL F S H+ +G+YL T G PD ++ +++ D+K+HT+ N D R A E +R LA T GR+H G I E DD+R+L EI A + + Q + ++K
Sbjct: 463 GTVKNIHVDPPFLY-KYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMY--IIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPARYASHTDTAAAYKEVTRAAGGRFHWFGDTG---IYESDDINSIMSEMEKALNYSQKCAFLMASLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSP---PLKSLKWRPLS----------SRVGISPAAAQ-----PTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSSIDLPRK---------DTVCSSQEWVAKY-GLKK-------LKLEISRCMGPNCTHQKS------GQRSASAKHCSIFPSVE-IHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAF-----SFHD--LEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSD----------RAA-----VEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLPPFEGDDLRILAQEITKARSFLWQAQSFRSQLQKK 1174 HSP 4 Score: 71.633 bits (174), Expect = 5.573e-11 Identity = 55/255 (21.57%), Postives = 113/255 (44.31%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTD--------------YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFK-KKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYH 1244
SS++W+ + L L+L I + + + +++ +A +C ++ + Y L + Y +R++W L GSR++FG V SK+ +L+D+S + + + + + L+ L+ EQL K S N+ F + + + E + + + + G +++QAL ++ + L+ PD +++ VQ+L RD+ H +S L+ +A+ + G YH
Sbjct: 861 SSQEWVAKYGLKKLKLEISRCMGPN-CTHQKSGQRSASAKHCSIFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQV--KTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYH 1112 HSP 5 Score: 70.0922 bits (170), Expect = 1.450e-10 Identity = 66/283 (23.32%), Postives = 121/283 (42.76%), Query Frame = 3
Query: 3132 EWITSKDWMKKYSLKNMGLDLLRLVS-GPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSG-SMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQ 3974
+W S+DW+ +SLK L L L+S G E E ++ K C ++ + + + + Y +R++WL +SK+ FG+I V+IL+D S S P E +L +LI EQL ++ + +++F + + S+ W + L G ++ +AL + + + PD +EI+ +Q S+ + IH I++ C+D+ LK LA G YH C+ + ++ R +++
Sbjct: 86 DWEDSEDWLSAHSLKCQKLTLADLISQGTEVLEEGTNVV-------QKIC-----------------FSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLF-VLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQ--STMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYH--CYSPKMEHYTSRDMDE 339 HSP 6 Score: 67.0106 bits (162), Expect = 1.523e-9 Identity = 72/286 (25.17%), Postives = 130/286 (45.45%), Query Frame = 3
Query: 2019 YQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIE---SDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMP 2861
++ L + +++ ++RI WL+ S++ FG I +V +++D+S IS+ + L LI +QL K+K +++F S V+ + LQ+ W+++L G NLL ALK +F +DS + PDQ E L YI++ +G D+ IH + + DD +P +++ LA + +G +H + S +E S D+ L+AEI A Q + HS E + E+ ++ +++L+P
Sbjct: 137 FESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDS--------LVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITYRCDDQ------MP---------PAVLKNLAEAVRGYYHCY--SPKMEHYTSRDMDELLAEIQKAQSLLSHVQAL----------QHSSPCEALTCTMEEISTEITNGPLISLLP 387
BLAST of von Willebrand factor A domain-containing protein 3A vs. UniProt/SwissProt
Match: sp|A1A5Q7|VWA3A_RAT (von Willebrand factor A domain-containing protein 3A OS=Rattus norvegicus OX=10116 GN=Vwa3a PE=2 SV=1) HSP 1 Score: 263.462 bits (672), Expect = 5.431e-73 Identity = 147/395 (37.22%), Postives = 232/395 (58.73%), Query Frame = 3
Query: 1710 FSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARL 2894
F+S + KP K + +L + S + G+K ++ +L+ NA+ EF+P + + V ++++EKAM+Q EW DG+V+N+H D LFEYQK LG+ V++ E+R+ WLS SRR +GT+ +R+V+++LD+S++N +++HI SL++L+++QL KD FNIIAF +T+ S++ + V+ NLQ +W W L C GSRN+LGAL+ E +QGIYLFT GVPDQ + L AY+ E G D++++ LF V + ++ TP P+ YA+ T TA + + + GRFHWF E+GI ESDD +++EI+ A+ YS++ ++ K +HS K + R L PP+ T+ S AR+
Sbjct: 355 FTSLLPKPPKHEAPLTIKFPDLDKTSAEWLKINGLKAK-------KLGLYQVLAPNAFNPVEEFVPILQKTVGATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEKRLQWLSLTSRRFWGTVCQRRVVILLDVSVTNSMFIIHIQHSLRLLLEEQLSNKDYFNIIAFGSTVESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKTKHESQGIYLFTGGVPDQDVHILSAYVAEACGGCDLQLNVCLFYVGEPQMNTTP-PACYASRTDTAAAYKEVTQAACGRFHWFGETGIYESDDSNAIVSEIEKALNYSQKCAFLVASLK-----NHSGKELLTAALQKDKPRTLQQSQPKKLYPPKPTAPSVARM 736 HSP 2 Score: 207.994 bits (528), Expect = 1.732e-54 Identity = 123/354 (34.75%), Postives = 194/354 (54.80%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT +NQ DLLR+Q + + + SEDWL H+L +LT+ DLIS+G + E A + + + + +L IE+Y +R++W + S+K FG + GS++ +LIDSS + G + FQ++L L+DEQL K+ + + FG T FL+ D + ++ ++E+K T+ G NL+QALK V K ++ ++ IL SCPDQ ++ L F+QQ LGR L H V+Y+ S+ILK + G+YH YS +E +YTS D+D LL E + Q + +++ + S I +I+ E+ P + LPKP PL + P + +TS+EW
Sbjct: 38 VTHVNQTQDLLRLQRSETQTSALEDSEDWLAMHSLKFEKLTLADLISQGTV----ELEDQNNAVPKVHFTTQTIYHFTSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSG-PQTEEFQNDLTSLIDEQLSLKEKLYVLTFGGTTNFLWPDPVEVSASTLQELKLWVKTLQPEGSSNLLQALKKVLARKELNSLVAILRSCPDQPSEFLSDFIQQSTLGRSLFIHIVTYKCDDHVPSAILKNLTDALGGHYHCYSPESE--LYTSRDVDELLAETHKAQGLFSQLQALCHNNPCEELSCMIEEISTEIAKGPFTSLLPKPPKHEAPLTIKFPDLD-KTSAEW 383 HSP 3 Score: 82.0333 bits (201), Expect = 2.444e-14 Identity = 66/223 (29.60%), Postives = 104/223 (46.64%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLE-------DPRIQGIYLLTDGKPDNSTEIV 3785
TS +W+K LK L L ++++ E + L+K V A + + GT K++ L +Y + KA+ Y KRL+WL ++S+R +G + + V ILLD S + + + + +L+ L+ EQL K +NIIAF S + +R +V + A W L G+ + AL +E QGIYL T G PD I+
Sbjct: 379 TSAEWLKINGLKAKKLGLYQVLAPNAFNPVEEFVPILQKTVGATIHEKAMVQFEWHDGTVKNIHVDPPVLFEYQKQLGKAVQIYEKRLQWLSLTSRRFWGTVCQRRVVILLDVSVTNSMFIIHIQHSLRLLLEEQL-SNKDYFNIIAFGSTVESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKTKHESQGIYLFTGGVPDQDVHIL 600 HSP 4 Score: 76.2554 bits (186), Expect = 1.500e-12 Identity = 72/306 (23.53%), Postives = 136/306 (44.44%), Query Frame = 3
Query: 633 GTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT----KEKSIDE---VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFH-CVSYETQSE-------------EVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPK 1487
GT N V D ++ +Y+ +L A+++Y KR++W SR+ +G V ++ +L+D S N F +I Q +L LL+EQL K NI FG+ + + + ++ ++ + G N++ AL+ K+K+ E + L G PDQ+ +L +V + G DL + C+ Y + + + ++ K + + G +H + E +Y S+D + ++ EIE+ +K + + N +EL ++ P+ + + P K PK
Sbjct: 436 GTVKNIHV-DPPVLFEYQKQLGKAVQIYEKRLQWLSLTSRRFWGTVCQRRVVILLDVSVTNSMF--IIHIQHSLRLLLEEQLSNKDYFNIIAFGSTVESWRPEMVAVSHDNLQRAWRWALGLQCQGSRNVLGALRKAIEVDFKDKTKHESQGIYLFTGGVPDQDVHILSAYVAEACGGCDLQLNVCLFYVGEPQMNTTPPACYASRTDTAAAYKEVTQAACGRFHWFG---ETGIYESDDSNAIVSEIEKALNYSQKCAFL--------VASLKNHSGKELLTAALQKDKPRTLQQSQPKKLYPPK 727 HSP 5 Score: 74.7146 bits (182), Expect = 4.748e-12 Identity = 68/263 (25.86%), Postives = 121/263 (46.01%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLS-ISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-ESGIIESDDIRVLMAE 2699
++ + + + +++E + +V VH ++ + L + ++L +QR+ WL+ S++ FG I +V L++D S +S+ L LI +QL K+K ++ F T + V+ + LQ+ W+++L GS NLL ALK V + PDQ E L +I++ LG + IH V + DD+ +PS I++ L + G +H + ES + S D+ L+AE
Sbjct: 76 KLTLADLISQGTVELEDQNNAVPKVHFTTQTIYHFTSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGPQTEEFQNDLTSLIDEQLSLKEKLYVLTFGGTTNFLWPDPVEVSASTLQELKLWVKTLQPEGSSNLLQALKKVLA-------RKELNSLVAILRSCPDQPSEFLSDFIQQSTLGRSLFIHIVTYKCDDH------VPS---------AILKNLTDALGGHYHCYSPESELYTSRDVDELLAE 316 HSP 6 Score: 67.781 bits (164), Expect = 6.850e-10 Identity = 61/278 (21.94%), Postives = 115/278 (41.37%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSG-SMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQ 3974
S+DW+ +SLK L L L+S G + + + +T + ++ + Y +R+ WL +SK+ FG+I + V +L+D+S S P E +L +LI EQL ++ Y ++ F V S+ W + L G+++ +AL L + + + PD +E + +Q S+ + IH +++ C+D + LK L G YH C+ + +++ R +++
Sbjct: 63 SEDWLAMHSLKFEKLTLADLIS-----------------------QGTVELEDQNNAVPKVHFTTQTIYHFTSRLSDTIELYQQRMRWLTENSKKAFGLIKGSRVGLLIDSSQVSSGPQTEEFQNDLTSLIDEQLSLKEKLY-VLTFGGTTNFLWPDPVEVSASTLQELKLWVKTLQPEGSSNLLQALKKVLARKELNSLVAILRSCPDQPSEFLSDFIQQ--STLGRSLFIHIVTYKCDDHVPSAILKNLTDALGGHYH--CYSPESELYTSRDVDE 312
BLAST of von Willebrand factor A domain-containing protein 3A vs. UniProt/SwissProt
Match: sp|Q502W6|VWA3B_HUMAN (von Willebrand factor A domain-containing protein 3B OS=Homo sapiens OX=9606 GN=VWA3B PE=1 SV=3) HSP 1 Score: 137.502 bits (345), Expect = 3.875e-31 Identity = 89/274 (32.48%), Postives = 133/274 (48.54%), Query Frame = 3
Query: 3144 SKDWMKKYSLKNMGLDLLRLVSGPECRHEEALII---------------PLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
SK W++KY LK L L +++ RH + ++ +K V AKYC+ G+ H+ T + YS AL R +R++WL S+ +FG + + IL+DTS SM + + + I EQL K K +N + F+ Q +RE+L +E + A W + +T+T AL D Q IYLLTDG+PD E V+ V+ R ++PI+TISFN DE AN FLK +A ++ G +H
Sbjct: 390 SKTWLQKYGLKAQKLSLYDVLADCSFRHADGVVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQL-KYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQPPETVIDQVK-----RFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFH 657 HSP 2 Score: 99.7525 bits (247), Expect = 1.568e-19 Identity = 76/267 (28.46%), Postives = 128/267 (47.94%), Query Frame = 3
Query: 3138 ITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFP-IVNVKGTRKHLQYTVTELNKYSVEA-KKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHL---VACGNTDTTKALLITLEDPRIQGIYLLTDGK-PDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
I+S+ W++ + LK+ L L +++S H E + L + V ++Y GLFP + + R + +EL VE +A+ Y +R++WL S++IFGVI E V I+LD G + + +L ++ ++ +NII + + +++E E S +AI W E L + ALL D I+ IY G P+ S E++L+ I P++T+SFN E FLK L+ ++ R+H
Sbjct: 34 ISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGEL-DLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEI------PCPVYTVSFNARGEGTIAFLKDLSAKTHSRFH 293 HSP 3 Score: 91.6633 bits (226), Expect = 3.820e-17 Identity = 125/524 (23.85%), Postives = 223/524 (42.56%), Query Frame = 3
Query: 1938 YEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR-------ESGIIESDDIRVLMAEI-----DLAVEYSRRTQQIINDY---KEKYPPSHSKKNEDIIKNAVELCRRNSSD-------NMVALMPPRQTSLSKARLKYL--SDKTEENLKIPKTLAYKSD-IDPRKSITNSKPPYR--------PVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQY---TVTELNKYSVEAKKALIRYMKRL 3401
Y + W DGS+ +V+ + Y + + + + +RI WL GS+ +FG + + +++D S S L + + IQ+QLK K KFN + F +++ L VNE NL+ + SW+R + S N L ALK F + Q IYL T G PDQ P I++ +I I+T+ FN +D I +R+ ++ +A T G FH++ ++++D+ +L+ E+ DL ++ +I D+ EK S +K + + E C + SD ++ L P S K + K + ++ T+ +L + + +S RK ++ R ++ + + +DK+S+ V G V ++S++W+K Y L L L+ +S H + L+K+V +K +FP+ +V + +LN Y + ++A+ Y KRL
Sbjct: 448 YCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFA-------DKETQAIYLLTDGRPDQ---PPETVIDQVKRFQEIPIYTISFNYND------EIANRF---------LKEVAALTGGEFHFYNFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQSDVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLSNASSRRTALSDKEMSILLAEEWLDDKSSEKVTRE-------------GSQVYDHDSSDVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNKMTLINPQGAKLNIYKRKVEQAIQSYEKRL 933 HSP 4 Score: 76.6406 bits (187), Expect = 1.448e-12 Identity = 86/321 (26.79%), Postives = 148/321 (46.11%), Query Frame = 3
Query: 1713 SSTIS-KPVKSRISQILTIDNLKEFSQFGSE----FEGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQV-EWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSG-VPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRE 2654
SSTIS + ++ + I T +L E S SE G+K + ++ + ILS+ + +++ S+GR V S + Q+ DG V N+ A ++++ + L + V+ +QR+ WL++ SR+IFG I+E+ V ++LD L ++L +++Q+Q+ +FNII S ++ T V E ++ + SW+ L + + G L + E D + IY F G VP++ E L+ +R L ++TV FN A T ++ L+ T RFH F E
Sbjct: 7 SSTISEQQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSN-------KLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKT----IESIYYFVVGDVPEESKELLL----QRALEIPCPVYTVSFN---------------ARGEGTIAFLKDLSAKTHSRFHAFAE 297 HSP 5 Score: 72.4034 bits (176), Expect = 2.724e-11 Identity = 52/226 (23.01%), Postives = 103/226 (45.58%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYS----SMTEELMYTSNDIDLLLLEIERTQEVLEKIE 1346
Y ++H A+ +RIKW GS+ +FG + + +LID+S + ++ +D ++ + EQL K N F + +N +E+ + + N + ALK +K + L+ PDQ + ++ V++ +++P + +S+ E + LK +A ++ G +H Y+ T + D+ LL+ E+E+ LEK++
Sbjct: 475 YSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMK--SKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQPPETVIDQVKRF---QEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYNFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQ 695 HSP 6 Score: 60.8474 bits (146), Expect = 9.415e-8 Identity = 56/278 (20.14%), Postives = 115/278 (41.37%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISK----------GKLGNPRPDE------------QTGTAYNCLVYDDFIVTDYEYKLHM--AIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSS---DANLGFGR---VISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEV-LLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTE 1265
SSE WL+ H L + +LT++ ++S+ LG P + G YN + I Y++ H+ A+E Y +R+ W SR++FG + + +++D + L R + Q+ + H+ + + + + + T Q V E + ++ + AL ++K+I+ + ++G P++ ++L+ Q L P + VS+ + E + LK ++ +H +H ++ TE
Sbjct: 35 SSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYRAEDGRVYNLTAKSELI---YQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFGGILEGELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKWQENATPVTEQSIATAISWV-----EKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLL----QRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTE 300
BLAST of von Willebrand factor A domain-containing protein 3A vs. TrEMBL
Match: A0A267FB75 (VWFA domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018061g1 PE=4 SV=1) HSP 1 Score: 715.687 bits (1846), Expect = 0.000e+0 Identity = 378/811 (46.61%), Postives = 515/811 (63.50%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIIN----DYKEKYPPSHSKK-------------NEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDI------DPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL--LITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQ-EQIKAEE 4214
IL+ NAY F+P I + V S V+EK M Q W DGSV+NVH DLAQLFEYQK LG VKL EQRI WL++ SR+IFGTI+ER ++ +LD+S +N+ YLVHI S+++L++QQ+ KD FN++AF + + F + V+E +LQ W W+ L C+GSRNLLGAL+ V EN + H Y +G+YLFTSG+PDQ E + AY+EE+ +G D+++H VLFNVDDYD G IP RYA+ITKTA+ +R LAH T GRFHWFRE+GIIESDDIR++M+EID AV +SRR + +I+ Y+E +P + K + D AL PP+ T+ S AR ++ D + +PK L + +P +S+ + R ++SAFYT ++N KG V DY G R+ +G+A IPDKE+ +TSK W K+YSL +GLDL RLVSGP+CRHEE L+ PL K V AKYC+GLFP VNV+G KHLQYT EL Y E +AL RY++RL WL+ S+R+FGV+ ET L+D SGSM P+M EL L LKAL+WEQL+K ++++N+IAF+S +R + L +E SCH+A+ W + L + GNT T +AL ++P + IYLLTDGKPD ST +L+++ + + R + IHTISFNC D +AN FL+ LA + GRYHKV ++D ++F+ R++E+S+ DP YP LP EGDDL RLAKEI R LAK YF+ L+ + ++ + E + A E
Sbjct: 497 QILAPNAYSYCEGFVPIIRKTVQSQVHEKVMAQFPWHDGSVKNVHVDLAQLFEYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNYLVHIQHSMRMLMEQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLRLHCVLFNVDDYDKDGA-IPGRYASITKTADSLRFLAHCTGGRFHWFRETGIIESDDIRLIMSEIDKAVNFSRRAKTLIDAVRSKYEEMFPDKYPKALGGGSGPESGGDDDPDGGSGGDGGGGGGGGAKPKALPPPKPTAKSLARQSFVRDALDSEPPVPKALGLRPGAASSVKAEPLESVRLN----RRCVKSAFYTGERNRKGQVISDYQG-GKSVRKAVGRAEIPDKEDQVTSKAWFKRYSLAKLGLDLYRLVSGPDCRHEEKLVKPLGKTVSAKYCSGLFPTVNVRGVTKHLQYTPVELQSYDAECVRALKRYLQRLHWLLSGSRRLFGVVVETRAVFLVDVSGSMAPYMEELKLALKALVWEQLYKFRVAFNLIAFSSGLRAWSPGLEPAEEDSCHAAVAWIDRLESMGNTATLEALEAAFATKEP-VDAIYLLTDGKPDTSTSTILRSINRLDAGR--NIAIHTISFNCCDATANNFLQCLASETGGRYHKVVEEFDAKLFAHRLLEESQLD-----------------------DPEYPNLPAFEGDDLSRLAKEIDSARRFLAKSKYFKDLYYETKRLRTENLGARE 1275 HSP 2 Score: 343.199 bits (879), Expect = 4.920e-94 Identity = 157/360 (43.61%), Postives = 246/360 (68.33%), Query Frame = 3
Query: 435 PPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
PP++ VT I+Q HDLLRV + ++QS+++WL+ H+++AL+LT++DL+ GKL P+PD +TG L +D V +EY+LH A++ Y++RIKW L+GSRK+FG V G ++AV +D SDAN+ FGR + Q LLHL+DEQL K+S+ + FGT + L+ + M++NCR +EE K T + GGCNL++AL+++++ + +D +L+++GS PDQ A +L F QL GRDL H V+++ S+ +S L+ +A ++ G +H YS+ ++EL+Y S+DI LL EI+ TQEVL+KI MR+G+ + +N+I+ E+ +PQS LP+P ++PLK E KF+P +S +W
Sbjct: 123 PPHELMVTQIDQTHDLLRVSGLEVGAAEQQSTQEWLQRHSVEALRLTVKDLVQLGKLTKPKPDAETGKPMPHLQFDAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVYMMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDSILIVVGSTPDQPADILEDFALQLSAGRDLRLHTVAFDCASQISNSGLRRLAEVTGGRFHCYSATSDELIYASSDISGLLQEIDTTQEVLKKIGEMRQGMLDSTLVSIMNEISMEVDKLPQSRFLPRPPGHDEPLKVEPAKFQPASSIDW 482 HSP 3 Score: 96.2857 bits (238), Expect = 4.913e-16 Identity = 75/293 (25.60%), Postives = 139/293 (47.44%), Query Frame = 3
Query: 3114 VIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKY---CAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDP-----RI--QGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESAN--------------EFLKRLARMSNGRYH 3920
V P K + +S DW+ + LK +DL ++++ + E + + K V+++ FP + G+ K++ + +L +Y + + Y +R+ WL SS++IFG I E ++ LLD S + ++ + +++ L+ EQ K +N++AF S++R F + +V E+S + W L G+ + AL LE+ R+ +G+YL T G PD E V ++ R + +H + FN +D + + L+ LA + GR+H
Sbjct: 469 VEPAKFQPASSIDWLMENGLKANKMDLYQILAPNAYSYCEGFVPIIRKTVQSQVHEKVMAQFPWHD--GSVKNVHVDLAQLFEYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNYLVHIQHSMRMLM-EQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLR--LHCVLFNVDDYDKDGAIPGRYASITKTADSLRFLAHCTGGRFH 756 HSP 4 Score: 82.4185 bits (202), Expect = 8.734e-12 Identity = 56/236 (23.73%), Postives = 114/236 (48.31%), Query Frame = 3
Query: 678 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYV------TKEKSIDEVLLILGS-CPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQS--------------EEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERT 1322
+Y+ +L +++Y +RI W SRK+FG + + L+D S AN+ + ++ Q ++ L+++Q+ K N+ FG+ +F + + ++ ++ + + G NL+ AL+ V K + E L + S PDQ A+ + ++++ +GRDL HCV + + + L+++A + G +H + E + S+DI L++ EI++
Sbjct: 549 EYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNY--LVHIQHSMRMLMEQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLRLHCVLFNVDDYDKDGAIPGRYASITKTADSLRFLAHCTGGRFHWFR---ETGIIESDDIRLIMSEIDKA 779 HSP 5 Score: 72.7886 bits (177), Expect = 7.846e-9 Identity = 64/296 (21.62%), Postives = 136/296 (45.95%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTS-GSMTPHMPELILN-LKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQD 4022
++++W++++S++ + L + LV L K + K P HLQ+ ++ ++ +A+ Y +R++W + S+++FG++ VA+ +D S +M+ E + L LI EQL ++ Y +++F ++++ ++ + + A + A G + KAL + I ++ PD +I+ + + R + +HT++F+C + +N L+RLA ++ GR+H C+ S +I S + +IDT Q+
Sbjct: 153 STQEWLQRHSVEALRLTVKDLVQ-------------LGKLTKPK------PDAETGKPMPHLQFDAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVY-MMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDSILIVVGSTPDQPADILEDFALQLSAGRDLR--LHTVAFDCASQISNSGLRRLAEVTGGRFH--CYSAT----SDELIYASSDISGLLQEIDTTQE 420 HSP 6 Score: 68.5514 bits (166), Expect = 1.356e-7 Identity = 62/261 (23.75%), Postives = 113/261 (43.30%), Query Frame = 3
Query: 1998 DLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKY---------LVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESG---IIESDDIRVLMAEIDLAVEYSRRTQQI 2741
D A + +++ L + V+ +RI W GSR++FG + +V + +D S +N+ + L+H++ Q +++F + + VN L+++ + + +G NLL AL+H+ VDS I + PDQ + L + + G D+++HTV F+ + I+ + +R LA T GRFH + + I S DI L+ EID E ++ ++
Sbjct: 198 DAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVY-------MMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDS--------ILIVVGSTPDQPADILEDFALQLSAGRDLRLHTVAFDC-------------ASQISNSG--LRRLAEVTGGRFHCYSATSDELIYASSDISGLLQEIDTTQEVLKKIGEM 428 HSP 7 Score: 67.781 bits (164), Expect = 2.104e-7 Identity = 59/266 (22.18%), Postives = 116/266 (43.61%), Query Frame = 3
Query: 516 DEQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----RPDEQTGTAYNC---------------LVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFK-KKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK--YVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHR 1247
D+ +S+ W K ++L L L + L+S + +P +T +A C L Y + Y+ + A++ Y +R+ W L GSR++FG V ++ L+D S + + + L L+ EQL+K + + N+ F + + + S+G ++AL+ + TKE +D + L+ PD ++ + +L GR++ H +S+ ++ L+ +A+ + G YH+
Sbjct: 938 DQVTSKAWFKRYSLAKLGLDLYRLVSGPDCRHEEKLVKPLGKTVSAKYCSGLFPTVNVRGVTKHLQYTPVELQSYDAECVRALKRYLQRLHWLLSGSRRLFGVVVETRAVFLVDVSGSMAPYMEELKLA--LKALVWEQLYKFRVAFNLIAFSSGLRAWSPGLEPAEEDSCHAAVAWIDRLESMGNTATLEALEAAFATKE-PVDAIYLLTDGKPDTSTSTILRSINRLDAGRNIAIHTISFNCCDATANNFLQCLASETGGRYHK 1200
BLAST of von Willebrand factor A domain-containing protein 3A vs. TrEMBL
Match: A0A267GGY9 (VWFA domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018061g3 PE=4 SV=1) HSP 1 Score: 715.687 bits (1846), Expect = 0.000e+0 Identity = 378/811 (46.61%), Postives = 513/811 (63.26%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIIN----DYKEKYPPSHSKK-------------NEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPY------RPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL--LITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQ-EQIKAEE 4214
IL+ NAY F+P I + V S V+EK M Q W DGSV+NVH DLAQLFEYQK LG VKL EQRI WL++ SR+IFGTI+ER ++ +LD+S +N+ YLVHI S+++L++QQ+ KD FN++AF + + F + V+E +LQ W W+ L C+GSRNLLGAL+ V EN + H Y +G+YLFTSG+PDQ E + AY+EE+ +G D+++H VLFNVDDYD G IP RYA+ITKTA+ +R LAH T GRFHWFRE+GIIESDDIR++M+EID AV +SRR + +I+ Y+E +P + K + D AL PP+ T+ S AR ++ D + +PK L + P + + P R ++SAFYT ++N KG V DY G R+ +G+A IPDKE+ +TSK W K+YSL +GLDL RLVSGP+CRHEE L+ PL K V AKYC+GLFP VNV+G KHLQYT EL Y E +AL RY++RL WL+ S+R+FGV+ ET L+D SGSM P+M EL L LKAL+WEQL+K ++++N+IAF+S +R + L +E SCH+A+ W + L + GNT T +AL ++P + IYLLTDGKPD ST +L+++ + + R + IHTISFNC D +AN FL+ LA + GRYHKV ++D ++F+ R++E+S+ DP YP LP EGDDL RLAKEI R LAK YF+ L+ + ++ + E + A E
Sbjct: 370 QILAPNAYSYCEGFVPIIRKTVQSQVHEKVMAQFPWHDGSVKNVHVDLAQLFEYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNYLVHIQHSMRMLMEQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLRLHCVLFNVDDYDKDGA-IPGRYASITKTADSLRFLAHCTGGRFHWFRETGIIESDDIRLIMSEIDKAVNFSRRAKTLIDAVRSKYEEMFPDKYPKALGGGSGPESGGDDDPDGGGGGDGGGGGGGGAKPKALPPPKPTAKSLARQSFVRDALDSEPPVPKALGLR----PGAASSVKAEPLESVRLNRRCVKSAFYTGERNRKGQVISDYQG-GKSVRKAVGRAEIPDKEDQVTSKAWFKRYSLAKLGLDLYRLVSGPDCRHEEKLVKPLGKTVSAKYCSGLFPTVNVRGVTKHLQYTPVELQSYDAECVRALKRYLQRLHWLLSGSRRLFGVVVETRAVFLVDVSGSMAPYMEELKLALKALVWEQLYKFRVAFNLIAFSSGLRAWSPGLEPAEEDSCHAAVAWIDRLESMGNTATLEALEAAFATKEP-VDAIYLLTDGKPDTSTSTILRSINRLDAGR--NIAIHTISFNCCDATANNFLQCLASETGGRYHKVVEEFDAKLFAHRLLEESQLD-----------------------DPEYPNLPAFEGDDLSRLAKEIDSARRFLAKSKYFKDLYYETKRLRTENLGARE 1148 HSP 2 Score: 335.109 bits (858), Expect = 4.538e-92 Identity = 155/354 (43.79%), Postives = 242/354 (68.36%), Query Frame = 3
Query: 453 VTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
VT I+Q HDLLRV + ++QS+++WL+ H+++AL+LT++DL+ GKL P+PD +TG L +D V +EY+LH A++ Y++RIKW L+GSRK+FG V G ++AV +D SDAN+ FGR + Q LLHL+DEQL K+S+ + FGT + L+ + M++NCR +EE K T + GGCNL++AL+++++ + +D +L+++GS PDQ A +L F QL GRDL H V+++ S+ +S L+ +A ++ G +H YS+ ++EL+Y S+DI LL EI+ TQEVL+KI MR+G+ + +N+I+ E+ +PQS LP+P ++PLK E KF+P +S +W
Sbjct: 2 VTQIDQTHDLLRVSGLEVGAAEQQSTQEWLQRHSVEALRLTVKDLVQLGKLTKPKPDAETGKPMPHLQFDAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVYMMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDSILIVVGSTPDQPADILEDFALQLSAGRDLRLHTVAFDCASQISNSGLRRLAEVTGGRFHCYSATSDELIYASSDISGLLQEIDTTQEVLKKIGEMRQGMLDSTLVSIMNEISMEVDKLPQSRFLPRPPGHDEPLKVEPAKFQPASSIDW 355 HSP 3 Score: 96.2857 bits (238), Expect = 4.498e-16 Identity = 75/293 (25.60%), Postives = 139/293 (47.44%), Query Frame = 3
Query: 3114 VIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKY---CAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDP-----RI--QGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESAN--------------EFLKRLARMSNGRYH 3920
V P K + +S DW+ + LK +DL ++++ + E + + K V+++ FP + G+ K++ + +L +Y + + Y +R+ WL SS++IFG I E ++ LLD S + ++ + +++ L+ EQ K +N++AF S++R F + +V E+S + W L G+ + AL LE+ R+ +G+YL T G PD E V ++ R + +H + FN +D + + L+ LA + GR+H
Sbjct: 342 VEPAKFQPASSIDWLMENGLKANKMDLYQILAPNAYSYCEGFVPIIRKTVQSQVHEKVMAQFPWHD--GSVKNVHVDLAQLFEYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNYLVHIQHSMRMLM-EQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLR--LHCVLFNVDDYDKDGAIPGRYASITKTADSLRFLAHCTGGRFH 629 HSP 4 Score: 81.6481 bits (200), Expect = 1.440e-11 Identity = 56/236 (23.73%), Postives = 114/236 (48.31%), Query Frame = 3
Query: 678 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVT------KEKSIDEVLLILGS-CPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQS--------------EEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERT 1322
+Y+ +L +++Y +RI W SRK+FG + + L+D S AN+ + ++ Q ++ L+++Q+ K N+ FG+ +F + + ++ ++ + + G NL+ AL+ V K + E L + S PDQ A+ + ++++ +GRDL HCV + + + L+++A + G +H + E + S+DI L++ EI++
Sbjct: 422 EYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNY--LVHIQHSMRMLMEQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLRLHCVLFNVDDYDKDGAIPGRYASITKTADSLRFLAHCTGGRFHWFR---ETGIIESDDIRLIMSEIDKA 652 HSP 5 Score: 72.4034 bits (176), Expect = 8.533e-9 Identity = 64/296 (21.62%), Postives = 136/296 (45.95%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTS-GSMTPHMPELILN-LKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQD 4022
++++W++++S++ + L + LV L K + K P HLQ+ ++ ++ +A+ Y +R++W + S+++FG++ VA+ +D S +M+ E + L LI EQL ++ Y +++F ++++ ++ + + A + A G + KAL + I ++ PD +I+ + + R + +HT++F+C + +N L+RLA ++ GR+H C+ S +I S + +IDT Q+
Sbjct: 26 STQEWLQRHSVEALRLTVKDLVQ-------------LGKLTKPK------PDAETGKPMPHLQFDAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVY-MMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDSILIVVGSTPDQPADILEDFALQLSAGRDLR--LHTVAFDCASQISNSGLRRLAEVTGGRFH--CYSAT----SDELIYASSDISGLLQEIDTTQE 293 HSP 6 Score: 68.1662 bits (165), Expect = 1.678e-7 Identity = 62/261 (23.75%), Postives = 113/261 (43.30%), Query Frame = 3
Query: 1998 DLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKY---------LVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESG---IIESDDIRVLMAEIDLAVEYSRRTQQI 2741
D A + +++ L + V+ +RI W GSR++FG + +V + +D S +N+ + L+H++ Q +++F + + VN L+++ + + +G NLL AL+H+ VDS I + PDQ + L + + G D+++HTV F+ + I+ + +R LA T GRFH + + I S DI L+ EID E ++ ++
Sbjct: 71 DAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVY-------MMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDS--------ILIVVGSTPDQPADILEDFALQLSAGRDLRLHTVAFDC-------------ASQISNSG--LRRLAEVTGGRFHCYSATSDELIYASSDISGLLQEIDTTQEVLKKIGEM 301 HSP 7 Score: 67.0106 bits (162), Expect = 3.912e-7 Identity = 59/266 (22.18%), Postives = 116/266 (43.61%), Query Frame = 3
Query: 516 DEQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----RPDEQTGTAYNC---------------LVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFK-KKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK--YVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHR 1247
D+ +S+ W K ++L L L + L+S + +P +T +A C L Y + Y+ + A++ Y +R+ W L GSR++FG V ++ L+D S + + + L L+ EQL+K + + N+ F + + + S+G ++AL+ + TKE +D + L+ PD ++ + +L GR++ H +S+ ++ L+ +A+ + G YH+
Sbjct: 811 DQVTSKAWFKRYSLAKLGLDLYRLVSGPDCRHEEKLVKPLGKTVSAKYCSGLFPTVNVRGVTKHLQYTPVELQSYDAECVRALKRYLQRLHWLLSGSRRLFGVVVETRAVFLVDVSGSMAPYMEELKLA--LKALVWEQLYKFRVAFNLIAFSSGLRAWSPGLEPAEEDSCHAAVAWIDRLESMGNTATLEALEAAFATKE-PVDAIYLLTDGKPDTSTSTILRSINRLDAGRNIAIHTISFNCCDATANNFLQCLASETGGRYHK 1073
BLAST of von Willebrand factor A domain-containing protein 3A vs. TrEMBL
Match: A0A267FB83 (VWFA domain-containing protein OS=Macrostomum lignano OX=282301 GN=BOX15_Mlig018061g2 PE=4 SV=1) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 378/811 (46.61%), Postives = 515/811 (63.50%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIIN----DYKEKYPPSHSKK-------------NEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDI------DPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL--LITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQ-EQIKAEE 4214
IL+ NAY F+P I + V S V+EK M Q W DGSV+NVH DLAQLFEYQK LG VKL EQRI WL++ SR+IFGTI+ER ++ +LD+S +N+ YLVHI S+++L++QQ+ KD FN++AF + + F + V+E +LQ W W+ L C+GSRNLLGAL+ V EN + H Y +G+YLFTSG+PDQ E + AY+EE+ +G D+++H VLFNVDDYD G IP RYA+ITKTA+ +R LAH T GRFHWFRE+GIIESDDIR++M+EID AV +SRR + +I+ Y+E +P + K + D AL PP+ T+ S AR ++ D + +PK L + +P +S+ + R ++SAFYT ++N KG V DY G R+ +G+A IPDKE+ +TSK W K+YSL +GLDL RLVSGP+CRHEE L+ PL K V AKYC+GLFP VNV+G KHLQYT EL Y E +AL RY++RL WL+ S+R+FGV+ ET L+D SGSM P+M EL L LKAL+WEQL+K ++++N+IAF+S +R + L +E SCH+A+ W + L + GNT T +AL ++P + IYLLTDGKPD ST +L+++ + + R + IHTISFNC D +AN FL+ LA + GRYHKV ++D ++F+ R++E+S+ DP YP LP EGDDL RLAKEI R LAK YF+ L+ + ++ + E + A E
Sbjct: 497 QILAPNAYSYCEGFVPIIRKTVQSQVHEKVMAQFPWHDGSVKNVHVDLAQLFEYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNYLVHIQHSMRMLMEQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLRLHCVLFNVDDYDKDGA-IPGRYASITKTADSLRFLAHCTGGRFHWFRETGIIESDDIRLIMSEIDKAVNFSRRAKTLIDAVRSKYEEMFPDKYPKALGGGSGPESGGDDDPDGGGGGDGGGGGGGGAKPKALPPPKPTAKSLARQSFVRDALDSEPPVPKALGLRPGAASSVKAEPLESVRLN----RRCVKSAFYTGERNRKGQVISDYQG-GKSVRKAVGRAEIPDKEDQVTSKAWFKRYSLAKLGLDLYRLVSGPDCRHEEKLVKPLGKTVSAKYCSGLFPTVNVRGVTKHLQYTPVELQSYDAECVRALKRYLQRLHWLLSGSRRLFGVVVETRAVFLVDVSGSMAPYMEELKLALKALVWEQLYKFRVAFNLIAFSSGLRAWSPGLEPAEEDSCHAAVAWIDRLESMGNTATLEALEAAFATKEP-VDAIYLLTDGKPDTSTSTILRSINRLDAGR--NIAIHTISFNCCDATANNFLQCLASETGGRYHKVVEEFDAKLFAHRLLEESQLD-----------------------DPEYPNLPAFEGDDLSRLAKEIDSARRFLAKSKYFKDLYYETKRLRTENLGARE 1275 HSP 2 Score: 343.199 bits (879), Expect = 4.874e-94 Identity = 157/360 (43.61%), Postives = 246/360 (68.33%), Query Frame = 3
Query: 435 PPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
PP++ VT I+Q HDLLRV + ++QS+++WL+ H+++AL+LT++DL+ GKL P+PD +TG L +D V +EY+LH A++ Y++RIKW L+GSRK+FG V G ++AV +D SDAN+ FGR + Q LLHL+DEQL K+S+ + FGT + L+ + M++NCR +EE K T + GGCNL++AL+++++ + +D +L+++GS PDQ A +L F QL GRDL H V+++ S+ +S L+ +A ++ G +H YS+ ++EL+Y S+DI LL EI+ TQEVL+KI MR+G+ + +N+I+ E+ +PQS LP+P ++PLK E KF+P +S +W
Sbjct: 123 PPHELMVTQIDQTHDLLRVSGLEVGAAEQQSTQEWLQRHSVEALRLTVKDLVQLGKLTKPKPDAETGKPMPHLQFDAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVYMMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDSILIVVGSTPDQPADILEDFALQLSAGRDLRLHTVAFDCASQISNSGLRRLAEVTGGRFHCYSATSDELIYASSDISGLLQEIDTTQEVLKKIGEMRQGMLDSTLVSIMNEISMEVDKLPQSRFLPRPPGHDEPLKVEPAKFQPASSIDW 482 HSP 3 Score: 96.2857 bits (238), Expect = 4.709e-16 Identity = 75/293 (25.60%), Postives = 139/293 (47.44%), Query Frame = 3
Query: 3114 VIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKY---CAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDP-----RI--QGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESAN--------------EFLKRLARMSNGRYH 3920
V P K + +S DW+ + LK +DL ++++ + E + + K V+++ FP + G+ K++ + +L +Y + + Y +R+ WL SS++IFG I E ++ LLD S + ++ + +++ L+ EQ K +N++AF S++R F + +V E+S + W L G+ + AL LE+ R+ +G+YL T G PD E V ++ R + +H + FN +D + + L+ LA + GR+H
Sbjct: 469 VEPAKFQPASSIDWLMENGLKANKMDLYQILAPNAYSYCEGFVPIIRKTVQSQVHEKVMAQFPWHD--GSVKNVHVDLAQLFEYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNYLVHIQHSMRMLM-EQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLR--LHCVLFNVDDYDKDGAIPGRYASITKTADSLRFLAHCTGGRFH 756 HSP 4 Score: 82.4185 bits (202), Expect = 8.025e-12 Identity = 56/236 (23.73%), Postives = 114/236 (48.31%), Query Frame = 3
Query: 678 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYV------TKEKSIDEVLLILGS-CPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQS--------------EEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERT 1322
+Y+ +L +++Y +RI W SRK+FG + + L+D S AN+ + ++ Q ++ L+++Q+ K N+ FG+ +F + + ++ ++ + + G NL+ AL+ V K + E L + S PDQ A+ + ++++ +GRDL HCV + + + L+++A + G +H + E + S+DI L++ EI++
Sbjct: 549 EYQKQLGHLVKLYEQRINWLASSSRKIFGTIVERNMLFLLDMSAANVNY--LVHIQHSMRMLMEQQMSNKDYFNLVAFGSEVRFFSKTMVKVSEASLQAGWKWILGLECAGSRNLLGALRKVLENEEEEKHRVYPEGLYLFTSGIPDQGAEQVSAYLEEKAVGRDLRLHCVLFNVDDYDKDGAIPGRYASITKTADSLRFLAHCTGGRFHWFR---ETGIIESDDIRLIMSEIDKA 779 HSP 5 Score: 72.7886 bits (177), Expect = 7.846e-9 Identity = 64/296 (21.62%), Postives = 136/296 (45.95%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTS-GSMTPHMPELILN-LKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQD 4022
++++W++++S++ + L + LV L K + K P HLQ+ ++ ++ +A+ Y +R++W + S+++FG++ VA+ +D S +M+ E + L LI EQL ++ Y +++F ++++ ++ + + A + A G + KAL + I ++ PD +I+ + + R + +HT++F+C + +N L+RLA ++ GR+H C+ S +I S + +IDT Q+
Sbjct: 153 STQEWLQRHSVEALRLTVKDLVQ-------------LGKLTKPK------PDAETGKPMPHLQFDAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVY-MMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDSILIVVGSTPDQPADILEDFALQLSAGRDLR--LHTVAFDCASQISNSGLRRLAEVTGGRFH--CYSAT----SDELIYASSDISGLLQEIDTTQE 420 HSP 6 Score: 68.5514 bits (166), Expect = 1.367e-7 Identity = 62/261 (23.75%), Postives = 113/261 (43.30%), Query Frame = 3
Query: 1998 DLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKY---------LVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFE-NPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESG---IIESDDIRVLMAEIDLAVEYSRRTQQI 2741
D A + +++ L + V+ +RI W GSR++FG + +V + +D S +N+ + L+H++ Q +++F + + VN L+++ + + +G NLL AL+H+ VDS I + PDQ + L + + G D+++HTV F+ + I+ + +R LA T GRFH + + I S DI L+ EID E ++ ++
Sbjct: 198 DAADVIQFEYRLHQAVQAYTERIKWCLRGSRKLFGLVQGERVAVCVDCSDANMSFGRAETLQQALLHLIDEQLSSKQSVY-------MMSFGTELQLLWPNVMDVNCRTLEEAKMFAMTRQAAGGCNLLKALRHLSRLRGVDS--------ILIVVGSTPDQPADILEDFALQLSAGRDLRLHTVAFDC-------------ASQISNSG--LRRLAEVTGGRFHCYSATSDELIYASSDISGLLQEIDTTQEVLKKIGEM 428 HSP 7 Score: 68.1662 bits (165), Expect = 1.983e-7 Identity = 59/266 (22.18%), Postives = 116/266 (43.61%), Query Frame = 3
Query: 516 DEQSSEDWLKTHNLDALQLTIEDLISKGKLGNP----RPDEQTGTAYNC---------------LVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFK-KKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALK--YVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHR 1247
D+ +S+ W K ++L L L + L+S + +P +T +A C L Y + Y+ + A++ Y +R+ W L GSR++FG V ++ L+D S + + + L L+ EQL+K + + N+ F + + + S+G ++AL+ + TKE +D + L+ PD ++ + +L GR++ H +S+ ++ L+ +A+ + G YH+
Sbjct: 938 DQVTSKAWFKRYSLAKLGLDLYRLVSGPDCRHEEKLVKPLGKTVSAKYCSGLFPTVNVRGVTKHLQYTPVELQSYDAECVRALKRYLQRLHWLLSGSRRLFGVVVETRAVFLVDVSGSMAPYMEELKLA--LKALVWEQLYKFRVAFNLIAFSSGLRAWSPGLEPAEEDSCHAAVAWIDRLESMGNTATLEALEAAFATKE-PVDAIYLLTDGKPDTSTSTILRSINRLDAGRNIAIHTISFNCCDATANNFLQCLASETGGRYHK 1200
BLAST of von Willebrand factor A domain-containing protein 3A vs. TrEMBL
Match: A0A2B4SKJ8 (von Willebrand factor A domain-containing protein 3A OS=Stylophora pistillata OX=50429 GN=Vwa3a PE=4 SV=1) HSP 1 Score: 696.427 bits (1796), Expect = 0.000e+0 Identity = 444/1319 (33.66%), Postives = 676/1319 (51.25%), Query Frame = 3
Query: 435 PPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKL-HMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFN--------DPLKFEVPKFEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTRDANISRKSIQGRRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKE-STDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKY---PPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSD-------KTEENLKI-PKT-------------------------------LAYK-SDIDPRKSITNSKPPYRPV-------------IQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQ 4193
PP TVTS++QA+DL V A + QSS DWL H++ A L+ +++ K G P KL H + ++ K FG V G +A+L+D+SD+N G+GR+ FQ++L L+DEQL K+ + FGT K L+ ++NCR++EE ++ GGCN++ ALK V K K ID ++L+LGSCPDQ K++ +V++ L GR P H V+Y+ + LK +A S G YH Y S ++E + T D+ L+ E+++ QE+L+KI M+ G+ ++ + L + QS L + S + PL E P F RTS+EWL + GLKAK L LY +L+ P S+ ++ + N + + +S+ ++ K V + L D ++G+ + S ++K+ + +L+ N++ +I +I R V S VYE++M Q +W DGSV+NVH D LF+YQ+ L V L ++R+ WLS G RRIFGT++E++VI++LD+SI + + L++L++QQ+ K +N I F + F+ + + L+ +W WL C GSRN L A + EN + H +GIY+ TSGVPD+ E + ++ E + GTD +HT+ + VDD D IP +YA+ TAE +R +AH+ GRFHW+R I+ESDD+ ++ E+D A YS++ I ++ PPS K + + L PPR T+L+KAR+K T E+L I P+T L +K ++ S+ + PP + V +Q AFYTE KN G V+ YP + RR I IPDKEE +++++WM+ YS+ + LDL +V EC H + + L + V A+YC+ +FP V VKG KHL EL Y + +K L RY+KRL+WL+ S+R+FG + E +V +L+DTSGSM M EL + AL+W+Q+ + +N+I F S++ ++ L++ + SC A+ W A G+T T +AL + EDP +QGIYLLTDGKPDNST +VL+ V + S R +V H ISFNC+D AN+FL+ LA + GRYH+ D + MF+ R++ + P + +P EGDDL RLA EI L R+ L + +R + +K Q
Sbjct: 83 PPKALTVTSVSQAYDLQAVIGLEAAHAEGQSSSDWLGRHSVKAEALSFNEIM---KCGVP------------------------IKLIHSFVGIFCKF---------DAFGLVKGQNVALLVDASDSNCGYGRLQLFQESLGELIDEQLANKERLFFLSFGTQPKPLWTVVRDVNCRIVEESHWWADSLHPQGGCNVLSALKQVVKRKEIDSIVLVLGSCPDQNPKVICEYVRESLAGRHAPLHTVAYDCSISATNMFLKELAEQSGGRYHCYVSTSDEQIMTGTDLSLIADEMKKAQEILKKIHEMKNGVIGDKKIVMQTGVDTTLSTVQQSLELMRIPSEDGEILKTDSSPLVVEHPSFPARTSAEWLRQHGLKAKGLNLY--QVLA----------PNSFSYVDGY----ISAINRNVHSLVYERSMAQFKWHDGSVKNV--HVDPTLLFD-----------YQGVFQLSVEKKQAKGLNLYQVLAPNSFSYVDGYISAINRNVHSLVYERSMAQFKWHDGSVKNVHVDPTLLFDYQRHLESAVHLYKRRVDWLSVGCRRIFGTVVEKRVIVLLDMSICMSPAVPKLQDHLRLLLEQQMANKTSYNFICFGDKTEMFRPVMLEPSPEYLEATWKWLLQRGCGGSRNFLDAFRKAVENDEEKAHGIEVEGIYVITSGVPDEPKEVVSGFLREALAGTDTGVHTIYYEVDDED-GLIAIPGKYADRGNTAECLRQMAHAVNGRFHWYRSGAIVESDDLGAVLNEMDKAFNYSQKIGDSIESENQQLVPRPPSAGK-------------------SRLPLTPPRHTALTKARMKKKGGCALPPIKATNEDLSIRPQTAGSSRPSSSTRGKKTRPQSASSQTKESTLKALQWKPPTVNSTSSLIPAPPPAKNVVKERRPSSGGVKAVQQAFYTEFKNETGAVFTQYPSKK-KLRRPIKHPFIPDKEESVSTREWMRHYSISKLKLDLNNIVGTAECSHAKGKVSSLGQSVTARYCS-IFPSVEVKGVVKHLHLLPHELEDYEDQVEKVLRRYVKRLQWLLSGSRRVFGTVVEKNVVVLIDTSGSMVSSMDELKREVAALVWDQIRHQATKFNLIRFASEVVSWKPSLMSTSDDSCQDAVEWVSGFDANGSTRTLQALQMAFEDPEVQGIYLLTDGKPDNSTTMVLREVAKLNSGRNVRV--HCISFNCDDSVANKFLQLLASQAGGRYHRCQGDPNGHMFTHRLLAEGFHEDEPLS------------------------MPVFEGDDLRRLASEIALCRKFLLQSRSYRTIADPTKKLQ 1288
BLAST of von Willebrand factor A domain-containing protein 3A vs. TrEMBL
Match: A0A1S3KGN7 (von Willebrand factor A domain-containing protein 3A OS=Lingula unguis OX=7574 GN=LOC106181528 PE=4 SV=1) HSP 1 Score: 632.869 bits (1631), Expect = 0.000e+0 Identity = 352/805 (43.73%), Postives = 491/805 (60.99%), Query Frame = 3
Query: 1806 EGIKESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAY-----KSDIDPR----KSITNSKPP-------YRPVIQSAFYTEDKNSKGVVYRDYPGQNMHS-RRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQL 4169
E +K++ + + ++++ +LS NAY K EFIP I + V S V+EKAM Q W DG+VRNVH DL Q+FEYQK LG VK+ E+RI WLS+GSR+IFG+I+E+ V+L++DLS+ N YL+HI SL++L++QQ+ ++ FNII F++ ++ + NLQ +W W+ L C GSRN L A + EN + H+ +G+YLFTSGVPDQ + Y+EE G IK+HT LFNVDDYD +G IP RYANITKTAE +R LAHST GRFHWFRE+G+IESDD++ ++AEID A+ +S++ ++ K+KY + E+ ++ S N L PP+ +LS ARLK +S+ +E+ +PK L + K I P T++K P Y+ FYT+DKN GVV++ YP NM S R+ I A+IP+KEE +T+K+W++ Y L + LDL +LV +CRH + + L K V AKYC +FP VN+ GT KHLQ E+ +Y +K L RY+KRL++L+ S+R+FGVI VAIL+DTSGSM HM EL L +LIW+QL+K +N+I F+ ++ E++V ES+CH AI W LVA GNT T AL ED ++ IYLLTDGKPD+ST +VL+ V + + R V ++TISFNC D +AN FLK LA ++GRYH+V D+D F+ +++ + A YP LP +GDDL RL EI R L + F +L
Sbjct: 428 EWLKQNGLKAKHLDLY--QVLSPNAYSFKEEFIPVIRKTVQSQVHEKAMAQFHWQDGTVRNVHVDLTQMFEYQKHLGSTVKVFEKRIEWLSSGSRKIFGSIVEKNVVLLIDLSLPNANYLIHIQHSLRLLLEQQISNREYFNIIGFTSRAEMWRPTMVKPTPENLQSAWRWVLGLQCGGSRNFLEAYRMTVENEEELKHHIEVEGVYLFTSGVPDQPHDVCAQYVEESCSGRGIKLHTALFNVDDYDSAGA-IPGRYANITKTAESLRNLAHSTGGRFHWFRETGVIESDDVQEILAEIDRAINFSQKCAMLVESVKKKYKAKELEYYEEQLQALPSSV--TPSKNKNTLPPPKMNALSLARLK-ISESQDES--VPKALTWRPSSAKDSIAPSPPKGNRPTSAKDPMMKVKSTYKKTTTQQFYTDDKNGIGVVFKRYP--NMKSVRKEIKLAMIPEKEEIMTTKEWLRLYGLSKLKLDLTKLVGSQDCRHVQGEVRTLNKIVPAKYC-DIFPHVNIGGTIKHLQLLPHEILEYQEMLEKVLRRYLKRLQFLLSGSRRVFGVICHKRVAILIDTSGSMDQHMEELRKELASLIWDQLYKLGAKFNLIRFSHTCEKWEEKMVDATESACHDAIRWVSKLVASGNTCTLDALDRAFEDEDLEAIYLLTDGKPDHSTSMVLREVAKMNTDR--HVAVNTISFNCTDSTANNFLKMLAAETSGRYHRVHSDFDAHRFAHKLLTEGFKEA------------------------EYPHLPEFDGDDLRRLGTEIAQARRFLTQARSFMEL 1195 HSP 2 Score: 327.405 bits (838), Expect = 7.378e-89 Identity = 151/359 (42.06%), Postives = 245/359 (68.25%), Query Frame = 3
Query: 438 PNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
P++ TVT +NQ L + +NN A +EQ+SE+WL+ H+++ +LT++DL++KGK G P D TG L +D + ++EY+LHM IE Y+KRIKW L GS++MFG V G+K+AV+IDSSDAN GFGR+ +FQ+ L+HL+DEQL K+ + + FG++ + +Q ++N R ++E K+ + + GGCNL++A+K++ + + I++++LILGS PDQ +++L ++ Q+ +G+ P H V+++ + + LK +A S G YH Y+S +EE +YT +DI LLL EI+ Q+V+ KI+ MR+G+ + N+I+ E+ +PQS+ LP+P ++PL+ E+PKF +TS EW
Sbjct: 71 PHELTVTHVNQTWSLNKGKNNTASKAEEQTSEEWLQNHSVEESKLTMKDLVAKGKPGKPTYDRTTGKVQQHLTFDAKDINEFEYRLHMQIEHYTKRIKWMLNGSKRMFGLVKGNKVAVVIDSSDANCGFGRLSNFQEALIHLIDEQLSGKQKLYLVKFGSDMEKCWQHVRDINHRTLDEAKDFVANLRPSGGCNLLKAMKHIYRLQDINQIVLILGSVPDQSSEVLTDYILQMGVGKHEPLHTVAFDCSNHLTNLTLKTLAAESRGRYHCYTSTSEEQIYTGSDISLLLKEIKNAQDVINKIKEMRKGMMGDALVSIENEISMEVTQVPQSQFLPRPPGHSNPLRIEMPKFLAKTSEEW 429 HSP 3 Score: 107.071 bits (266), Expect = 2.610e-19 Identity = 78/282 (27.66%), Postives = 140/282 (49.65%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVK-GTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDP-------RIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCED-ESAN-------------EFLKRLARMSNGRYH 3920
TS++W+K+ LK LDL +++S +E I + K V+++ + + GT +++ +T++ +Y + + KR+EWL S++IFG I E +V +L+D S ++ + +L+ L+ +Q+ R+ +NII F S+ +R +V P + SA W L G+ + +A +T+E+ ++G+YL T G PD ++ + V+ S R K +HT FN +D +SA E L+ LA + GR+H
Sbjct: 425 TSEEWLKQNGLKAKHLDLYQVLSPNAYSFKEEFIPVIRKTVQSQVHEKAMAQFHWQDGTVRNVHVDLTQMFEYQKHLGSTVKVFEKRIEWLSSGSRKIFGSIVEKNVVLLIDLSLPNANYLIHIQHSLRLLLEQQISNREY-FNIIGFTSRAEMWRPTMVKPTPENLQSAWRWVLGLQCGGSRNFLEAYRMTVENEEELKHHIEVEGVYLFTSGVPDQPHDVCAQYVEESCSGRGIK--LHTALFNVDDYDSAGAIPGRYANITKTAESLRNLAHSTGGRFH 703 HSP 4 Score: 81.6481 bits (200), Expect = 1.353e-11 Identity = 71/281 (25.27%), Postives = 128/281 (45.55%), Query Frame = 3
Query: 3105 GKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKG-TRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTS------GSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKAL--LITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
GK K E TS++W++ +S++ L + LV AK G G ++HL + ++N++ + Y KR++W++ SKR+FG++ VA+++D+S G ++ LI LI EQL ++ Y ++ F S + + + + + + A + +L G + KA+ + L+D I I L+ PD S+E++ + + + P+HT++F+C + N LK LA S GRYH
Sbjct: 88 GKNNTASKAEEQTSEEWLQNHSVEESKLTMKDLV--------------------AKGKPGKPTYDRTTGKVQQHLTFDAKDINEFEYRLHMQIEHYTKRIKWMLNGSKRMFGLVKGNKVAVVIDSSDANCGFGRLSNFQEALI----HLIDEQLSGKQKLY-LVKFGSDMEKCWQHVRDINHRTLDEAKDFVANLRPSGGCNLLKAMKHIYRLQD--INQIVLILGSVPDQSSEVLTDYILQMGVGKHE--PLHTVAFDCSNHLTNLTLKTLAAESRGRYH 339 HSP 5 Score: 77.7962 bits (190), Expect = 1.834e-10 Identity = 73/259 (28.19%), Postives = 123/259 (47.49%), Query Frame = 3
Query: 1998 DLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKY--LVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWF---RESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKE 2759
D + E++ L Q++ +RI W+ GS+R+FG + KV +++D S +N + L + ++L LI +QL K K ++ F + + + +N L ++ ++ +L SG NLL A+KH++ D Q I L VPDQ E L YI + +G +HTV F+ ++ N+T ++ LA ++GR+H + E I DI +L+ EI + Q +IN KE
Sbjct: 145 DAKDINEFEYRLHMQIEHYTKRIKWMLNGSKRMFGLVKGNKVAVVIDSSDANCGFGRLSNFQEALIHLIDEQLSGKQKLYLVKFGSDMEKCWQHVRDINHRTLDEAKDFVANLRPSGGCNLLKAMKHIYR------LQDINQ-IVLILGSVPDQSSEVLTDYILQMGVGKHEPLHTVAFDCSNH----------LTNLT-----LKTLAAESRGRYHCYTSTSEEQIYTGSDISLLLKEI-------KNAQDVINKIKE 374 HSP 6 Score: 68.9366 bits (167), Expect = 1.026e-7 Identity = 70/344 (20.35%), Postives = 141/344 (40.99%), Query Frame = 3
Query: 522 QSSEDWLKTHNLDALQLTIEDLISKG-------------KLGNPRPDE--------QTGTAYNCLVYDDFIVTDYEYKLHMA--IEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEK-------SIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEE-----------VSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQS 1430
++SE+WLK + L A L + ++S K + E Q GT N V+ D + +EY+ H+ ++++ KRI+W GSRK+FG + + +LID S N + +I Q +L LL++Q+ ++ NI F + + + ++ + G N ++A + + + ++ V L PDQ + +V++ GR + H + + ++ + + ++H R+ E + S+D+ +L EI+R +K ++ + + + E+L+ +P S
Sbjct: 424 KTSEEWLKQNGLKAKHLDLYQVLSPNAYSFKEEFIPVIRKTVQSQVHEKAMAQFHWQDGTVRN--VHVD-LTQMFEYQKHLGSTVKVFEKRIEWLSSGSRKIFGSIVEKNVVLLIDLSLPNANY--LIHIQHSLRLLLEQQISNREYFNIIGFTSRAEMWRPTMVKPTPENLQSAWRWVLGLQCGGSRNFLEAYRMTVENEEELKHHIEVEGVYLFTSGVPDQPHDVCAQYVEESCSGRGIKLHTALFNVDDYDSAGAIPGRYANITKTAESLRNLAHSTGGRFHWFRETGVIESDDVQEILAEIDRAINFSQKCAMLVESVKKKYKAKELEYYEEQLQALPSS 762 HSP 7 Score: 63.5438 bits (153), Expect = 4.647e-6 Identity = 52/263 (19.77%), Postives = 110/263 (41.83%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISK------------------GKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFK-KKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSS 1256
++++WL+ + L L+L + L+ K + P G L + +Y+ L + Y KR+++ L GSR++FG + ++A+LID+S + + + L L+ +QL+K N+ F + + ++ + S + + G + AL +++ ++ + L+ PD M++ V ++ R + + +S+ ++ LK +A + G YHR S
Sbjct: 880 TTKEWLRLYGLSKLKLDLTKLVGSQDCRHVQGEVRTLNKIVPAKYCDIFPHVNIGGTIKHLQLLPHEILEYQEMLEKVLRRYLKRLQFLLSGSRRVFGVICHKRVAILIDTSGSM--DQHMEELRKELASLIWDQLYKLGAKFNLIRFSHTCEKWEEKMVDATESACHDAIRWVSKLVASGNTCTLDALDRAFEDEDLEAIYLLTDGKPDHSTSMVLREVAKMNTDRHVAVNTISFNCTDSTANNFLKMLAAETSGRYHRVHS 1140
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Cavefish
Match: ENSAMXT00000000373.2 (von Willebrand factor A domain containing 3A [Source:NCBI gene;Acc:103035332]) HSP 1 Score: 475.707 bits (1223), Expect = 9.885e-146 Identity = 274/786 (34.86%), Postives = 433/786 (55.09%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLS-TGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDV-SGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVA----LMPPRQTSLSKARLKYLSDKTEENLK-------IPKTLAYKSDIDPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSID---PHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQL 4169
+L+ N Y K F+P + + V S+V+EKAM+Q EW DG+V+NVH DL L YQK L E +++E R WLS TGSR+I+G + E++V ++LD+S N Y +HI ++ +L+Q+QL + FNI AF + I +K + NLQD W W++ L C G R L A++H E + S + G+YLFT+G+PDQ + Y+ E +KIH +LF ++ S TP RY +TA+++R LAH++KGRFHW ++GI+ESDD+ L+ E++ A Y ++ ++++ ++ S S+ + + ++ E C L PPR T LS ARL+ K + + IP S P + + ++K + QS FY ED N G V++ Y + ++ I IP +E+ ++K W+K + +++ LDL +LVSGPEC H + L+ + K V AKYCA +FP V V G+ +HL + EL +Y ++ +K L RY +R++WL+ S+R+FG + E V ++LD SGSM P +PEL L +LIWEQL + ++++AF+ ++R ++ LV E C A+ W L G T + +AL G+YL+TDG+ D S +VLK + + + + + IHTI+FNC+D +A EFL++LA + GR+H+ + T A++LL+ LP+ EGDDL RL++E++ R + FR++
Sbjct: 398 QVLAPNVYSPKESFVPILRKTVHSTVHEKAMVQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAEL-STDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTP---RYVTWAETAQVLRGLAHASKGRFHWITDTGIVESDDVIALIGEMETAANYWQKCCELLDSLVQR---SSSRMDAEEAQSQ-ECCNPVQCSQTWTRGHKLPPPRPTQLSLARLESKEGKRSQTWRPSSAKAVIPPAHPVDS-WKPARQVNSAKQRKTKITQSVFYLEDGN-LGTVFKKYL-KPKSVQKYISTVTIPKQEDICSTKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYCA-IFPSVQVNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGK--HITIHTIAFNCQDRTAKEFLRKLAHKTGGRFHEA----------------------------PSESHTAAASELLTSSFSVGEDSELPSFEGDDLRRLSEEMEKLRMFQKQARAFREI 1141 HSP 2 Score: 166.777 bits (421), Expect = 3.742e-41 Identity = 107/341 (31.38%), Postives = 174/341 (51.03%), Query Frame = 3
Query: 516 DEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTD--------YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
D +SS +WL+ +L++ LT+ L S TA DD + T +E +L+ ++Y RI+W QGSRKMFG V GS+L VLID SD N R+ Q +LL L++EQ KK ++ FGT L+ + ++E ++ + G CNL+QALK +D +L+ILGSCPDQ+ + ++ Q + + H V+Y T ++ +K IA ++ G YH +S+ ++ +S+D++ L EI+ ++VL+ I M G + P +++I+E+L + S+ P + L + P P TS+EW
Sbjct: 56 DWRSSVEWLEECSLNSYGLTLTHLFS-----------HCSTAATS-SRDDGVSTQLEIDSKKLFETQLYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLEPSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCNQVAIENVKNIAKVTEGRYHIFSAAL-GVVDSSSDLEPLWAEIKSARDVLDHIHCMSHGQLEDLTVPVMSEISEDLDCLSLSDLKSDPHDGSAALCIQPPTLLPTTSAEW 383 HSP 3 Score: 117.472 bits (293), Expect = 5.324e-26 Identity = 169/715 (23.64%), Postives = 297/715 (41.54%), Query Frame = 3
Query: 633 GTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQ-GSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTK-EKSIDE-----VLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQS-------------EEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEK-IELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFND------------PLKFEVPKFEPRT---SSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTR--DANISRKSIQGRRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIK-----ESTDEKRFIEMFTENILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXX-XXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTA-EIMRMLAHSTKGRFH 2642
GT N V D ++ +Y+ +L A ++ R W GSR+++G V ++ VL+D S N + I +L LL EQL S NI FG++ K + + ++++ + + G + A+++ + E S D V L PDQ+ + ++ ++ L H + + ++ E + +L+ +A S G +H +T+ + S+D+ L+ E+E +K EL+ + R+S ++ AEE QS+ P+ + P + + + E + S W S + A N+ ++ T VF L + N + KS+Q ++ ST++ P + I T LK F + + K E T K+ + +++ +K PS +QV +GSVR++ A+L +Y + + ++ QR+ WL +GSRR+FG ++ER V ++LD+S S + + + L LI +Q +F+++AFS + ++ L +E +++ WL L+ G + L AL+ D + G+YL T G D ++ E G I IHT+ FN D +TA E +R LAH T GRFH
Sbjct: 436 GTVKNVHV-DLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHL--LLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAELSTDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTPRYVTWAETAQVLRGLAHASKGRFHW---ITDTGIVESDDVIALIGEMETAANYWQKCCELLDSLV--QRSSSRMD--AEE----AQSQECCNPVQCSQTWTRGHKLPPPRPTQLSLARLESKEGKRSQTWRPSSAKAVIPPAHPVDSWKPARQVNSAKQRKTKI----TQSVFYLEDGNLGTVFKKYLKPKSVQ--KYISTVTIPKQEDICS--TKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYC-----AIFPS--------------VQV---NGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQ------AGCAFGD-SLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQD----------------RTAKEFLRKLAHKTGGRFH 1083 HSP 4 Score: 72.0182 bits (175), Expect = 5.013e-12 Identity = 101/408 (24.75%), Postives = 172/408 (42.16%), Query Frame = 3
Query: 1971 DGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNI--KYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRES-GIIE-SDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYP-PSHSKKNEDIIKNAVELCRRNSSDNMVALM--PPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSA--------FYTEDKNSKGVVYRDYP-GQNMHSRRGIGKAVIPDKEEWITS 3146
DG + D +LFE Q L + L RI WL+ GSR++FG + ++ +++D+S N + L + L +LI++Q + K + ++F +SS G V L++S W+ L SGS NLL ALK + + + + PDQ + + Y+ + V IH V +N + E ++ +A T+GR+H F + G+++ S D+ L AEI A + + + E P S+ +ED+ ++ + + D AL PP + A + + L + + LA + P++S P R + S F D K V+ D P QN R + V+ D+ W++S
Sbjct: 93 DGVSTQLEIDSKKLFETQ--LYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLEPSGSCNLLQALK-------TACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCN---------------QVAIENVKNIAKVTEGRYHIFSAALGVVDSSSDLEPLWAEIKSARDVLDHIHCMSHGQLEDLTVPVMSEISEDLDCLSLSDLKSDPHDGSAALCIQPPTLLPTTSAEWLKTNGMKAKKLSLYQVLA-PNVYSPKESFV---PILRKTVHSTVHEKAMVQFEWHDGTVKN-VHVDLPLLQNYQKRLLEAEQVLEDRAAWLSS 471 HSP 5 Score: 62.3882 bits (150), Expect = 4.220e-9 Identity = 62/309 (20.06%), Postives = 131/309 (42.39%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISKGKLGN----PRPDEQTGTAYNCLVYDDFIVT--------------DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKK-SINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHR-----YSSMTEELMYTS----NDIDLLLLE---IERTQEVLEKIELMRR 1358
S++ WLK+ + + +L + L+S + + R ++ +A C ++ V Y ++ ++ Y++R++W L GSR++FG V + V++D S + V Q L L+ EQL ++ F + + + + +E + +S+ GG + +QAL+ V LI D +++ ++L G+ + H +++ Q L+ +A + G +H +++ EL+ +S D +L E + R E +EK+ + ++
Sbjct: 827 STKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYCAIFPSVQVNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPC--VPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQDRTAKEFLRKLAHKTGGRFHEAPSESHTAAASELLTSSFSVGEDSELPSFEGDDLRRLSEEMEKLRMFQK 1133 HSP 6 Score: 62.003 bits (149), Expect = 5.214e-9 Identity = 58/271 (21.40%), Postives = 118/271 (43.54%), Query Frame = 3
Query: 3129 EEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTS--GSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRF--RERLVTP---DESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
++W +S +W+++ SL + GL L L S +C+ G L+ +L + + + Y R++WL S+++FG++ + + +L+D S + +L +L LI EQ F+ K + ++F +++ + VTP ES W L G+ + +AL ++ + ++ PD T+ + + + + T IH +++N ++ A E +K +A+++ GRYH
Sbjct: 55 DDWRSSVEWLEECSLNSYGLTLTHLFS---------------------HCSTAATSSRDDGVSTQLEIDSKKL--FETQLYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQ-FRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQ-----QWVLQLEPSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTS--IHVVAYNTCNQVAIENVKNIAKVTEGRYH 294
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Cavefish
Match: ENSAMXT00000042735.1 (von Willebrand factor A domain containing 3A [Source:NCBI gene;Acc:103035332]) HSP 1 Score: 456.062 bits (1172), Expect = 4.030e-139 Identity = 264/776 (34.02%), Postives = 416/776 (53.61%), Query Frame = 3
Query: 1860 NILSKNAYESKSEFIPSIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLS-TGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDV-SGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSD-IDPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSID---PHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQL 4169
+L+ N Y K F+P + + V S+V+EKAM+Q EW DG+V+NVH DL L YQK L E +++E R WLS TGSR+I+G + E++V ++LD+S N Y +HI ++ +L+Q+QL + FNI AF + I +K + NLQD W W++ L C G R L A++H E + S + G+YLFT+G+PDQ + Y+ E +KIH +LF ++ S TP RY +TA+++R LAH++KGRFHW ++GI+ESDD+ L+ E++ A Y ++ + + + PS +K A++PP A+ D P + + ++K + QS FY ED N G V++ Y + ++ I IP +E+ ++K W+K + +++ LDL +LVSGPEC H + L+ + K V AKYCA +FP V V G+ +HL + EL +Y ++ +K L RY +R++WL+ S+R+FG + E V ++LD SGSM P +PEL L +LIWEQL + ++++AF+ ++R ++ LV E C A+ W L G T + +AL G+YL+TDG+ D S +VLK + + + + + IHTI+FNC+D +A EFL++LA + GR+H+ + T A++LL+ LP+ EGDDL RL++E++ R + FR++
Sbjct: 398 QVLAPNVYSPKESFVPILRKTVHSTVHEKAMVQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVLEDRAAWLSSTGSRQIWGAVCEQRVHVLLDMSAMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAEL-STDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLKIHVILFAGENMLARSLTP---RYVTWAETAQVLRGLAHASKGRFHWITDTGIVESDDVIALIGEMETAANYWQKESKE-GKRSQTWRPSSAK----------------------AVIPP---------------------------AHPVDSWKPARQVNSAKQRKTKITQSVFYLEDGN-LGTVFKKYL-KPKSVQKYISTVTIPKQEDICSTKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYCA-IFPSVQVNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPCVPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGK--HITIHTIAFNCQDRTAKEFLRKLAHKTGGRFHEA----------------------------PSESHTAAASELLTSSFSVGEDSELPSFEGDDLRRLSEEMEKLRMFQKQARAFREI 1086 HSP 2 Score: 166.392 bits (420), Expect = 3.862e-41 Identity = 107/341 (31.38%), Postives = 174/341 (51.03%), Query Frame = 3
Query: 516 DEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTD--------YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
D +SS +WL+ +L++ LT+ L S TA DD + T +E +L+ ++Y RI+W QGSRKMFG V GS+L VLID SD N R+ Q +LL L++EQ KK ++ FGT L+ + ++E ++ + G CNL+QALK +D +L+ILGSCPDQ+ + ++ Q + + H V+Y T ++ +K IA ++ G YH +S+ ++ +S+D++ L EI+ ++VL+ I M G + P +++I+E+L + S+ P + L + P P TS+EW
Sbjct: 56 DWRSSVEWLEECSLNSYGLTLTHLFS-----------HCSTAATS-SRDDGVSTQLEIDSKKLFETQLYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLEPSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCNQVAIENVKNIAKVTEGRYHIFSAAL-GVVDSSSDLEPLWAEIKSARDVLDHIHCMSHGQLEDLTVPVMSEISEDLDCLSLSDLKSDPHDGSAALCIQPPTLLPTTSAEW 383 HSP 3 Score: 73.559 bits (179), Expect = 1.406e-12 Identity = 72/286 (25.17%), Postives = 126/286 (44.06%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAK-YCAGLFPIVNVKGTRKHLQYTVTELNKYS---VEAKKALIRYMKRLEWLM-ISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALL------ITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESAN-------------EFLKRLARMSNGRYHKV 3926
TS +W+K +K L L ++++ +E+ + L K V + + + GT K++ + L Y +EA++ L R WL S++I+G + E V +LLD S +M H I + L+ ++ S+NI AF S I++++E++V P + W + L G+ T A+ ++ + G+YL T G PD V + + ++ + K IH I F E+ A + L+ LA S GR+H +
Sbjct: 379 TSAEWLKTNGMKAKKLSLYQVLAPNVYSPKESFVPILRKTVHSTVHEKAMVQFEWHDGTVKNVHVDLPLLQNYQKRLLEAEQVL---EDRAAWLSSTGSRQIWGAVCEQRVHVLLDMS-AMNNHYQLHIQHAVHLLLQEQLPSTHSFNITAFGSDIKQWKEQMVPPTSENLQDVWQWIQGLECGGDRYTLAAIQHAAEAELSTDSSLTSGVYLFTTGMPDQDPVTVSTYMSEVCNNPRLK--IHVILFAGENMLARSLTPRYVTWAETAQVLRGLAHASKGRFHWI 658 HSP 4 Score: 71.633 bits (174), Expect = 6.349e-12 Identity = 101/408 (24.75%), Postives = 172/408 (42.16%), Query Frame = 3
Query: 1971 DGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNI--KYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRES-GIIE-SDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYP-PSHSKKNEDIIKNAVELCRRNSSDNMVALM--PPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSA--------FYTEDKNSKGVVYRDYP-GQNMHSRRGIGKAVIPDKEEWITS 3146
DG + D +LFE Q L + L RI WL+ GSR++FG + ++ +++D+S N + L + L +LI++Q + K + ++F +SS G V L++S W+ L SGS NLL ALK + + + + PDQ + + Y+ + V IH V +N + E ++ +A T+GR+H F + G+++ S D+ L AEI A + + + E P S+ +ED+ ++ + + D AL PP + A + + L + + LA + P++S P R + S F D K V+ D P QN R + V+ D+ W++S
Sbjct: 93 DGVSTQLEIDSKKLFETQ--LYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQFRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQQWVLQLEPSGSCNLLQALK-------TACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTSIHVVAYNTCN---------------QVAIENVKNIAKVTEGRYHIFSAALGVVDSSSDLEPLWAEIKSARDVLDHIHCMSHGQLEDLTVPVMSEISEDLDCLSLSDLKSDPHDGSAALCIQPPTLLPTTSAEWLKTNGMKAKKLSLYQVLA-PNVYSPKESFV---PILRKTVHSTVHEKAMVQFEWHDGTVKN-VHVDLPLLQNYQKRLLEAEQVLEDRAAWLSS 471 HSP 5 Score: 62.003 bits (149), Expect = 5.054e-9 Identity = 63/316 (19.94%), Postives = 135/316 (42.72%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISKGKLGN----PRPDEQTGTAYNCLVYDDFIVT--------------DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKK-SINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHR-----YSSMTEELMYTS----NDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPY 1388
S++ WLK+ + + +L + L+S + + R ++ +A C ++ V Y ++ ++ Y++R++W L GSR++FG V + V++D S + V Q L L+ EQL ++ F + + + + +E + +S+ GG + +QAL+ V LI D +++ ++L G+ + H +++ Q L+ +A + G +H +++ EL+ +S D +L E + + + E++E +R +F +A +
Sbjct: 772 STKQWLKSFGIRSQKLDLHKLVSGPECTHRKKLVRTVHKSVSAKYCAIFPSVQVNGSVRHLLLSPAELKQYLIQVEKVLQRYAQRMQWLLSGSRRVFGCVVERAVCVVLDVSGSMAPC--VPELQKELASLIWEQLHANSVRFSMVAFSGEVRVWQVELVEASEERCKEAVQWLGQLSTHGGTSSLQALQAGCAFGDSLGVYLITDGRNDCSCSLVLKEAERLTAGKHITIHTIAFNCQDRTAKEFLRKLAHKTGGRFHEAPSESHTAAASELLTSSFSVGEDSELPSFEGDDLRRLSEEMEKLR--MFQKQARAF 1083 HSP 6 Score: 62.003 bits (149), Expect = 5.097e-9 Identity = 58/271 (21.40%), Postives = 118/271 (43.54%), Query Frame = 3
Query: 3129 EEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTS--GSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRF--RERLVTP---DESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
++W +S +W+++ SL + GL L L S +C+ G L+ +L + + + Y R++WL S+++FG++ + + +L+D S + +L +L LI EQ F+ K + ++F +++ + VTP ES W L G+ + +AL ++ + ++ PD T+ + + + + T IH +++N ++ A E +K +A+++ GRYH
Sbjct: 55 DDWRSSVEWLEECSLNSYGLTLTHLFS---------------------HCSTAATSSRDDGVSTQLEIDSKKL--FETQLYQVTDLYHSRIQWLNQGSRKMFGIVKGSRLGVLIDVSDVNCSEERLEDLQHHLLLLIEEQ-FRMKKVLHFMSFGTELSSLWTGPKEVTPLRLKESQ-----QWVLQLEPSGSCNLLQALKTACSHTQLDSLLIILGSCPDQDTDSIFNYMTQEVQEKVTS--IHVVAYNTCNQVAIENVKNIAKVTEGRYH 294
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Cavefish
Match: si:dkey-8l13.5 (chromosome 18 C11orf16 homolog [Source:NCBI gene;Acc:103047275]) HSP 1 Score: 61.6178 bits (148), Expect = 4.552e-9 Identity = 49/181 (27.07%), Postives = 84/181 (46.41%), Query Frame = 3
Query: 3411 MISSKRIFGVITETD--VAILLDTSGSMTPHMPELILNLKALIWEQLFK----RKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISF---NCEDESANEFLKRLARMSNGRYHKV 3926
M SS+ + V+ D V ++LDTS +MT ++ +K LI + L R +NII F+ ++ + + +V + + A+GW L D AL DP Q ++L+T+ PDN +N + +S+ T+ P+HT D +FLK L + G +++
Sbjct: 1 MDSSRGVIPVLMGKDRNVTLILDTSEAMT----AVLGTVKNLIVQTLLAKASLRNSLFNIITFSYKVTPWSDHMVPCAPDTVYEALGWIHTLTTSPGKDLLTALTTAFSDPACQSVHLVTNSLPDNP-----ENCLSALSTCGTR-PVHTFHIAEKQALDSDTLDFLKCLTSATRGSCYRL 171
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Cavefish
Match: ENSAMXT00000037803.1 (inter-alpha-trypsin inhibitor heavy chain H3-like [Source:NCBI gene;Acc:103044542]) HSP 1 Score: 53.9138 bits (128), Expect = 1.508e-6 Identity = 47/192 (24.48%), Postives = 87/192 (45.31%), Query Frame = 3
Query: 3453 DVAILLDTSGSMTP----HMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLE-------DPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALP 3995
+V ++D SGSM+ E +L + + E + + +I F+S+I +R LV +S+ SA + + + G TD A+L +E + + LLTDG P+ + N+ + K P++ + F + +FL+++A ++GR ++ D D + Q KT A+P
Sbjct: 270 NVVFVIDRSGSMSGKKIQQTREALLKILGDVAEDDY-----FGLITFDSKIEVWRPELVQATDSNLKSAKNFVKEITDRGATDINAAVLKGVEMINRHQREGSASILILLTDGAPNTGVSHPPRIQANVKEAIGGKFPLYCLGFGFDVNY--DFLEKMALENSGRAFRIYEDSDADLQLQGFY---KTVAVP 451
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Cavefish
Match: ENSAMXT00000057721.1 (inter-alpha-trypsin inhibitor heavy chain H3-like [Source:NCBI gene;Acc:103044542]) HSP 1 Score: 53.5286 bits (127), Expect = 1.680e-6 Identity = 47/192 (24.48%), Postives = 87/192 (45.31%), Query Frame = 3
Query: 3453 DVAILLDTSGSMTP----HMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLE-------DPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALP 3995
+V ++D SGSM+ E +L + + E + + +I F+S+I +R LV +S+ SA + + + G TD A+L +E + + LLTDG P+ + N+ + K P++ + F + +FL+++A ++GR ++ D D + Q KT A+P
Sbjct: 270 NVVFVIDRSGSMSGKKIQQTREALLKILGDVAEDDY-----FGLITFDSKIEVWRPELVQATDSNLKSAKNFVKEITDRGATDINAAVLKGVEMINRHQREGSASILILLTDGAPNTGVSHPPRIQANVKEAIGGKFPLYCLGFGFDVNY--DFLEKMALENSGRAFRIYEDSDADLQLQGFY---KTVAVP 451
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008921.1 (pep scaffold:Pmarinus_7.0:GL477596:1845:16253:1 gene:ENSPMAG00000008072.1 transcript:ENSPMAT00000008921.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 168.703 bits (426), Expect = 1.849e-47 Identity = 106/242 (43.80%), Postives = 153/242 (63.22%), Query Frame = 3
Query: 1941 EKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLF--NVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESG 2660
+KAM Q EW +G+V+N+H DL L YQK LG+ V+ EQR++WLS+GSRRI+GT+ E ++ +++DLS N YLVH+ S+++L+Q QL K+ FNII F I +F+ + NLQ +WSW+ C G R+LLGAL+ + E+P +GIY+FTSGVPDQ + + Y+EE LG ++++H LF GT P+ YA+ +TAE +R LA + +GR H F E G
Sbjct: 1 QKAMTQFEWHNGTVKNMHVDLPTLHNYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANYLVHVQHSMRLLLQTQLTGKESFNIITFGMDIQAFRPSPVPPSPENLQAAWSWVLEWRCGGGRDLLGALRLLLEDP-----EGPPEGIYVFTSGVPDQDLVAVCGYVEEANLGQEVRLHACLFSAGGSGSGGGGTSGPACYASGAETAEALRALARAGRGRLHCFSEQG 237 HSP 2 Score: 77.0258 bits (188), Expect = 1.089e-15 Identity = 49/155 (31.61%), Postives = 80/155 (51.61%), Query Frame = 3
Query: 3309 GTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPR--IQGIYLLTDGKPD 3767
GT K++ + L+ Y + +A+ Y +R+ WL S+RI+G + E +A+L+D S ++ + +++ L+ QL ++ S+NII F I+ FR V P + +A W G D AL + LEDP +GIY+ T G PD
Sbjct: 12 GTVKNMHVDLPTLHNYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANYLVHVQHSMRLLLQTQLTGKE-SFNIITFGMDIQAFRPSPVPPSPENLQAAWSWVLEWRCGGGRDLLGALRLLLEDPEGPPEGIYVFTSGVPD 165 HSP 3 Score: 56.9954 bits (136), Expect = 5.954e-9 Identity = 29/83 (34.94%), Postives = 49/83 (59.04%), Query Frame = 3
Query: 678 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTK 926
+Y+ +L A+ Y +R+ W GSR+++G V +LAVL+D S+ N + ++ Q ++ LL QL K+S NI FG + +
Sbjct: 26 NYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANY--LVHVQHSMRLLLQTQLTGKESFNIITFGMDIQ 106
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000008919.1 (pep scaffold:Pmarinus_7.0:GL477596:1845:16253:1 gene:ENSPMAG00000008072.1 transcript:ENSPMAT00000008919.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 164.466 bits (415), Expect = 7.364e-46 Identity = 109/246 (44.31%), Postives = 156/246 (63.41%), Query Frame = 3
Query: 1941 EKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQ-IEPLMA---YIEERVLGTDIKIHTVLF--NVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESG 2660
+KAM Q EW +G+V+N+H DL L YQK LG+ V+ EQR++WLS+GSRRI+GT+ E ++ +++DLS N YLVH+ S+++L+Q QL K+ FNII F I +F+ + NLQ +WSW+ C G R+LLGAL+ + E+P +GIY+FTSGVPDQ I+ L+A Y+EE LG ++++H LF GT P+ YA+ +TAE +R LA + +GR H F E G
Sbjct: 1 QKAMTQFEWHNGTVKNMHVDLPTLHNYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANYLVHVQHSMRLLLQTQLTGKESFNIITFGMDIQAFRPSPVPPSPENLQAAWSWVLEWRCGGGRDLLGALRLLLEDP-----EGPPEGIYVFTSGVPDQDLIKHLVAVCGYVEEANLGQEVRLHACLFSAGGSGSGGGGTSGPACYASGAETAEALRALARAGRGRLHCFSEQG 241 HSP 2 Score: 77.0258 bits (188), Expect = 1.151e-15 Identity = 49/155 (31.61%), Postives = 80/155 (51.61%), Query Frame = 3
Query: 3309 GTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPR--IQGIYLLTDGKPD 3767
GT K++ + L+ Y + +A+ Y +R+ WL S+RI+G + E +A+L+D S ++ + +++ L+ QL ++ S+NII F I+ FR V P + +A W G D AL + LEDP +GIY+ T G PD
Sbjct: 12 GTVKNMHVDLPTLHNYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANYLVHVQHSMRLLLQTQLTGKE-SFNIITFGMDIQAFRPSPVPPSPENLQAAWSWVLEWRCGGGRDLLGALRLLLEDPEGPPEGIYVFTSGVPD 165 HSP 3 Score: 56.9954 bits (136), Expect = 6.259e-9 Identity = 29/83 (34.94%), Postives = 49/83 (59.04%), Query Frame = 3
Query: 678 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTK 926
+Y+ +L A+ Y +R+ W GSR+++G V +LAVL+D S+ N + ++ Q ++ LL QL K+S NI FG + +
Sbjct: 26 NYQKQLGQAVRTYEQRVSWLSSGSRRIWGTVCEMRLAVLVDLSEMNANY--LVHVQHSMRLLLQTQLTGKESFNIITFGMDIQ 106
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Sea Lamprey
Match: ENSPMAT00000001432.1 (pep scaffold:Pmarinus_7.0:GL485617:3236:10216:1 gene:ENSPMAG00000001295.1 transcript:ENSPMAT00000001432.1 gene_biotype:protein_coding transcript_biotype:protein_coding) HSP 1 Score: 112.079 bits (279), Expect = 3.519e-26 Identity = 76/233 (32.62%), Postives = 109/233 (46.78%), Query Frame = 3
Query: 3111 AVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEK--------------YVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPD 3767
A + E +S+ W+ +Y L+ GL L + RH + ++ V A+YC+ + G H+ Y+V AL RLEWL S+ +FG I E V IL+DTS SM + L L LI EQL + K +N++ F S+ +R ++V ES A W E L A G+TDT AL + L DP +G+YLL+DG+PD
Sbjct: 198 ASVRSAEAEQSSRAWLARYGLEARGLALHTALGRCAFRHADGVVDSAHGDCACACAQGRRRRVLVNARYCSCFVHTLWADGALVHVYVPERVYRDYAVRLTAALRLIQSRLEWLQRGSRALFGSIVEDRVYILIDTSLSMEDKLDLLKEKLYLLIDEQL-RYKSGFNLVRFGSRAGAWRRQIVDTTESHLDDARAWVESLEAGGSTDTLGALRLALGDPATEGVYLLSDGRPD 429 HSP 2 Score: 88.1965 bits (217), Expect = 2.433e-18 Identity = 53/179 (29.61%), Postives = 99/179 (55.31%), Query Frame = 3
Query: 1917 RMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQ 2453
R++ ++ Y + W DG++ +V+ +Y L ++L++ R+ WL GSR +FG+I+E +V +++D S+S L + + L +LI +QL+ K FN++ F + +++ + E++L D+ +W+ SL GS + LGAL+ +P +G+YL + G PDQ
Sbjct: 259 RVLVNARYCSCFVHTLWADGALVHVYVPERVYRDYAVRLTAALRLIQSRLEWLQRGSRALFGSIVEDRVYILIDTSLSMEDKLDLLKEKLYLLIDEQLRYKSGFNLVRFGSRAGAWRRQIVDTTESHLDDARAWVESLEAGGSTDTLGALRLALGDPA-------TEGVYLLSDGRPDQ 430 HSP 3 Score: 54.6842 bits (130), Expect = 1.075e-7 Identity = 33/144 (22.92%), Postives = 71/144 (49.31%), Query Frame = 3
Query: 669 IVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQ 1100
+ DY +L A+ + R++W +GSR +FG + ++ +LID+S + ++ ++ L L+DEQL K N+ FG+ + ++ +++ + ++ + G + + AL+ + + + V L+ PDQ
Sbjct: 289 VYRDYAVRLTAALRLIQSRLEWLQRGSRALFGSIVEDRVYILIDTSLSME--DKLDLLKEKLYLLIDEQLRYKSGFNLVRFGSRAGAWRRQIVDTTESHLDDARAWVESLEAGGSTDTLGALRLALGDPATEGVYLLSDGRPDQ 430
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Nematostella
Match: EDO28327 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7T6S8]) HSP 1 Score: 108.612 bits (270), Expect = 4.780e-24 Identity = 57/143 (39.86%), Postives = 87/143 (60.84%), Query Frame = 3
Query: 3519 LKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHD-YDI 3944
L L+ EQL + K+ +N++ ++++++ +R+RLV + + +A W + L G+T+T AL + L DP+ + IYLLTDG+PD +L V + VPIHTISFNC D ANEFL +LA +N R+H D YD+
Sbjct: 12 LYRLMQEQL-RHKVKFNLMKYDTRVQAWRDRLVDCNSHNLDNAWQWVKGLSTGGSTNTLAALKLALTDPQCRAIYLLTDGRPDQPPSSILAQVHLL-----NPVPIHTISFNCADTEANEFLCKLAADTNARFHYFSEDGYDV 148 HSP 2 Score: 85.1149 bits (209), Expect = 1.022e-16 Identity = 51/167 (30.54%), Postives = 77/167 (46.11%), Query Frame = 3
Query: 2226 FNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGI-------IESDDIRVLMAEID 2705
FN++ + + +++ L N NL ++W W++ L+ GS N L ALK +P + IYL T G PDQ ++A + L + IHT+ FN D T+ E + LA T RFH+F E G ES+D+R+L EI+
Sbjct: 26 FNLMKYDTRVQAWRDRLVDCNSHNLDNAWQWVKGLSTGGSTNTLAALKLALTDP-------QCRAIYLLTDGRPDQPPSSILAQVH---LLNPVPIHTISFNCAD---------------TEANEFLCKLAADTNARFHYFSEDGYDVNGPKPFESEDLRLLREEIE 167 HSP 3 Score: 57.7658 bits (138), Expect = 2.887e-8 Identity = 42/181 (23.20%), Postives = 80/181 (44.20%), Query Frame = 3
Query: 825 GRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEEL----MYTSNDIDLLLLEIERTQEVLEKIELMR 1355
R+ +D L L+ EQL K N+ + T + ++ N ++ + +S+ G N + ALK + + L+ PDQ ++ Q+ L +P H +S+ E + L +A ++ +H +S ++ + S D+ LL EIE+ + L+K+ L+R
Sbjct: 3 SRLFLVKDKLYRLMQEQLRHKVKFNLMKYDTRVQAWRDRLVDCNSHNLDNAWQWVKGLSTGGSTNTLAALKLALTDPQCRAIYLLTDGRPDQPPSSIL---AQVHLLNPVPIHTISFNCADTEANEFLCKLAADTNARFHYFSEDGYDVNGPKPFESEDLRLLREEIEKGLKDLKKVALLR 180
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Nematostella
Match: EDO41655 (Predicted protein [Source:UniProtKB/TrEMBL;Acc:A7S3S3]) HSP 1 Score: 93.2041 bits (230), Expect = 1.390e-21 Identity = 60/169 (35.50%), Postives = 91/169 (53.85%), Query Frame = 3
Query: 3429 IFGVITETDVAILLDTSGSMTPHMPELILN--LKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNC---EDESANEFLKRLARMSNGRYH 3920
IFG I E +V LLDTSGSM H +++ ++ L + R +N+I FN ++ ++ +R+V + A W L +T+T ALL +D +Q IYL+TDG PD I+++NV+ + R PIH I + C D +A EFL+ LA+ +NG H
Sbjct: 15 IFGNILERNVVFLLDTSGSMY-HCLDVVREHLIEILFFRATSGRDTMFNVIEFNEEVTKWADRMVQCTPRTVSVASEWINKLQCGTSTNTMGALLEAYDDDGMQAIYLVTDGMPDQRPGIIMENVRKLHKGR----PIHAI-YLCGAKADVAAVEFLEDLAKETNGSLH 177 HSP 2 Score: 57.3806 bits (137), Expect = 3.236e-9 Identity = 48/185 (25.95%), Postives = 73/185 (39.46%), Query Frame = 3
Query: 2094 IFGTIIERKVILILDLSISNIKYL--VHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFH 2642
IFG I+ER V+ +LD S S L V + + FN+I F+ ++ + + + + W+ L C S N +GAL ++ +D Q IYL T G+PDQ+ +M + R L IH + DV+ E + LA T G H
Sbjct: 15 IFGNILERNVVFLLDTSGSMYHCLDVVREHLIEILFFRATSGRDTMFNVIEFNEEVTKWADRMVQCTPRTVSVASEWINKLQCGTSTNTMGALLEAYD-------DDGMQAIYLVTDGMPDQRPGIIMENV--RKLHKGRPIHAIYLCGAKADVAAV-------------EFLEDLAKETNGSLH 177
BLAST of von Willebrand factor A domain-containing protein 3A vs. Planmine SMEST
Match: SMESG000022332.1 (SMESG000022332.1) HSP 1 Score: 1564.28 bits (4049), Expect = 0.000e+0 Identity = 771/771 (100.00%), Postives = 771/771 (100.00%), Query Frame = 3
Query: 1920 MVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQEQIKAEEIKAHLI 4232
MVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHILQSLKILIQQQLKAKDKFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQEQIKAEEIKAHLI
Sbjct: 1 MVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHILQSLKILIQQQLKAKDKFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEKYPPSHSKKNEDIIKNAVELCRRNSSDNMVALMPPRQTSLSKARLKYLSDKTEENLKIPKTLAYKSDIDPRKSITNSKPPYRPVIQSAFYTEDKNSKGVVYRDYPGQNMHSRRGIGKAVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMFSQRVIEQSKTTALPQNDIDTKQDRTTVAADLLSIDPHYPPLPNLEGDDLVRLAKEIQLTRENLAKINYFRQLHIQLQKYQEQIKAEEIKAHLI 771 HSP 2 Score: 74.7146 bits (182), Expect = 4.110e-13 Identity = 61/263 (23.19%), Postives = 120/263 (45.63%), Query Frame = 3
Query: 525 SSEDWLKTHNLDALQLTIEDLISKGKLGNPR----PDEQTGTAYNC---------------LVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKK-SINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGR--DLPFHCVSYETQSEEVSSILKYIATISHGNYHR 1247
+S+DW+K ++L + L + L+S + + P E+ A C L Y + Y + A+ Y KR++W + S+++FG ++ + +A+L+D+S + + NL L+ EQLFK+K S NI F + + + + + + + G + +AL ++ I + L+ PD ++++ VQ ++ R +P H +S+ + E + LK +A +S+G YH+
Sbjct: 408 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELIL--NLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHK 668 HSP 3 Score: 74.7146 bits (182), Expect = 4.326e-13 Identity = 60/249 (24.10%), Postives = 115/249 (46.18%), Query Frame = 3
Query: 678 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEV--------LLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSS---------------ILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIE-------RTQEVL 1334
+Y+ L +++ +RI W GSR++FG + K+ +++D S +N+ + ++ +L L+ +QL K NI F +N +++ +++ G NL+ ALK+V E +D V L PDQ+ + LM ++++ +LG D+ H V + +VS I++ +A + G +H + E + S+DI +L+ EI+ RTQ+++
Sbjct: 33 EYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKY--LVHILQSLKILIQQQLKAKDKFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVF-ENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR---ESGIIESDDIRVLMAEIDLAVEYSRRTQQII 275
BLAST of von Willebrand factor A domain-containing protein 3A vs. Planmine SMEST
Match: SMESG000022334.1 (SMESG000022334.1) HSP 1 Score: 1114.75 bits (2882), Expect = 0.000e+0 Identity = 593/595 (99.66%), Postives = 595/595 (100.00%), Query Frame = 3
Query: 81 MYRKDKVAVAVDSYKRKYSDDENEDSLQXXXXXXXXXXXXXXXXXXXXXXIIEDNKTKAIKSVKAANRATNLIEKKQVEGFNMFLNKIKPTDXXXXXXXXXXXKVKNFEIIDRNKKYYPPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEWXXXXXXXXXXXXXYSKNILSATMANNFERNPTSYPVIEMSDVFPLRESNFTRDANISRKSIQGRRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENI 1865
MYRKDKVAVAVDSYKRKYSDDENEDSLQNNSNNIDKENESEKSSSDERNEIIEDNKTKAIKSVKAANRATNLIEKKQVEGFNMFLNKIKPTDNRNSNNQNSSNKVKNFEIIDRNKKYYPPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEWLGKSGLKAKKLGLYSKNILSATMANNFERNPTSYP+IEMSDVFPLRESNFTRDANISRKSIQGRRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTEN+
Sbjct: 1 MYRKDKVAVAVDSYKRKYSDDENEDSLQNNSNNIDKENESEKSSSDERNEIIEDNKTKAIKSVKAANRATNLIEKKQVEGFNMFLNKIKPTDNRNSNNQNSSNKVKNFEIIDRNKKYYPPNQFTVTSINQAHDLLRVQNNPAVSGDEQSSEDWLKTHNLDALQLTIEDLISKGKLGNPRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIERTQEVLEKIELMRRGIFSNRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEWLGKSGLKAKKLGLYSKNILSATMANNFERNPTSYPLIEMSDVFPLRESNFTRDANISRKSIQGRRFSSTISKPVKSRISQILTIDNLKEFSQFGSEFEGIKESTDEKRFIEMFTENV 595 HSP 2 Score: 74.7146 bits (182), Expect = 2.907e-13 Identity = 61/263 (23.19%), Postives = 120/263 (45.63%), Query Frame = 3
Query: 3141 TSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELIL--NLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHK 3923
+S+DW+K ++L + L + L+S + + P E+ A C L Y + Y + A+ Y KR++W + S+++FG ++ + +A+L+D+S + + NL L+ EQLFK+K S NI F + + + + + + + G + +AL ++ I + L+ PD ++++ VQ ++ R +P H +S+ + E + LK +A +S+G YH+
Sbjct: 149 SSEDWLKTHNLDALQLTIEDLISKGKLGNPR----PDEQTGTAYNC---------------LVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKK-SINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGR--DLPFHCVSYETQSEEVSSILKYIATISHGNYHR 389 HSP 3 Score: 63.5438 bits (153), Expect = 8.479e-10 Identity = 67/254 (26.38%), Postives = 125/254 (49.21%), Query Frame = 3
Query: 2016 EYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKY--LVHXXXXXXXXXXXXXXXXXXFNIIAF-SNTISSFKAGLT----VVNETNLQDSWSWLRSLNCSGSRNLLGALKHVF-ENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFR---ESGIIESDDIRVLMAEIDLAVEYSRRTQQII 2744
+Y+ L +++ +RI W GSR++FG + K+ +++D S +N+ + ++ +L L+ +QL K NI F +NT ++ + V+ E +++S+S + SL G NL+ ALK+V E +D V L PDQ+ + LM ++++ +LG D+ H V + +VS I++ +A + G +H + E + S+DI +L+ EI+ RTQ+++
Sbjct: 200 DYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEE--IKESFSTMSSL---GGCNLMQALKYVTKEKSIDEV--------LLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSS---------------ILKYIATISHGNYHRYSSMTEELMYTSNDIDLLLLEIE-------RTQEVL 418
BLAST of von Willebrand factor A domain-containing protein 3A vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 183.341 bits (464), Expect = 1.212e-46 Identity = 109/289 (37.72%), Postives = 156/289 (53.98%), Query Frame = 3
Query: 3111 AVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLE-------------------KYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
AV +EE+++S++W+ KY LK+ LD ++SG RH + ++ LE K + AKYC + G+ H+Q + YS K L+ +R+EWL S+ +FG I E V IL+D S SM PH+ + L LI EQL + K N +AFN++ +R+RLV E++ SA W E L G+T+T AL ++D QGIYLLTDG+PD T+ VL ++ + ++PIHTISFNC D AN FL LAR + GR+H
Sbjct: 399 AVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQL-RHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIR-----LQYRLPIHTISFNCADLEANTFLCELARETGGRFH 681 HSP 2 Score: 119.013 bits (297), Expect = 1.285e-26 Identity = 91/286 (31.82%), Postives = 144/286 (50.35%), Query Frame = 3
Query: 1908 SIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKL----MEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRE-SG-----------IIESDDIRVLMAEIDLAVE 2717
++ + + ++ Y V+W DGS+ VH ++ + +L E++KL + +RI WL GSR +FGTI+E +V +++D+S S ++ + L LIQ+QL+ K K N +AF+ ++ L V E NL+ +W WL L C GS N L AL+ ++ + QGIYL T G PDQ + +++ I L + IHT+ FN D + + + LA T GRFH+F E SG ES+DI++L +E L +
Sbjct: 462 TLHQKLINAKYCDKFAHVKWKDGSL--VHVQMSS--DVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQF-------AIKDRNCQGIYLLTDGRPDQPTKTVLSQIR---LQYRLPIHTISFNCADLEANT---------------FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFD 718 HSP 3 Score: 88.9669 bits (219), Expect = 1.764e-17 Identity = 74/291 (25.43%), Postives = 132/291 (45.36%), Query Frame = 3
Query: 3120 PDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFP--------IVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKIS-YNIIAFNSQIRRFRERLVTPDESSCHSAIGW---TEHLVACGNTDTTKALLITLEDPRIQGIYLLT-DGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMF 3953
PD + ++S+ W+ K+ LK LD L E L+K + ++Y LFP NV ++ L EL + A+ Y +RLEWL S+R+FGVI E V I++D + I ++ + EQ+ R I+ +N+I + L+ + + + I W + A + + +AL+ + + +YL+T D D S E++ + V+ + K+P++ IS+NC+D +LK L M+ GR+H + ++ +
Sbjct: 50 PDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQEL-------ENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQI--RCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL------KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAY 325 HSP 4 Score: 80.4925 bits (197), Expect = 8.022e-15 Identity = 60/235 (25.53%), Postives = 110/235 (46.81%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISF-QDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMT---------EELMYTSNDIDLLLLEIERTQEVLEKIELMR 1355
Y ++ + + ++RI+W QGSR++FG + ++ +LID S + ISF +D L L+ EQL K IN F T +++ ++ + ++ G N + AL++ K+++ + L+ PDQ K ++ Q+ L LP H +S+ E ++ L +A + G +H ++ ++ E + S DI LL E + LEK+ +R
Sbjct: 499 YSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISAS---MEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVL---SQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLR 727 HSP 5 Score: 63.929 bits (154), Expect = 9.265e-10 Identity = 74/293 (25.26%), Postives = 129/293 (44.03%), Query Frame = 3
Query: 1971 DGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLN---CSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPD-----------QQIE-PL------------MAYIEERVLGTDIKIHTVLFN--VDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEK 2762
DG NV A +L + Q+ L V+L +QR+ WLS+ SRR+FG I E V +I+D+ N + + +++ + +Q++ KFN+I L V++ NL + WL ++ + S NL+ AL + + +N + +YL T + +Q++ PL ++Y++ VL T + H+ LFN VD Y+ S + AN+ K + + GI +D + +EI+ A + + +IN EK
Sbjct: 113 DGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEAL-------IRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLL------------LKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEK 386 HSP 6 Score: 52.373 bits (124), Expect = 2.768e-6 Identity = 87/370 (23.51%), Postives = 156/370 (42.16%), Query Frame = 3
Query: 525 SSEDWL-----KTHNLDALQL----------TIEDLISK---GKLGN---PRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDAN-LGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFM-----NLNCRV--IEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGS-CPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDL------LLLEIERTQEVLEKIELMRR--GIFS--NRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
SSE WL K NLD+ L D++ K + G+ P+ + G +N + + ++ + +L A+++Y +R++W SR++FG + + ++ID + N F + I + L+EQ+ N+ N L + + NL + + +I + +T S+ NL++AL + K + + LI D ++L V+QL +P + +SY + E S LK + ++ G +H Y E Y S+ +D LLL+ + + I +FS A INQI + IP+ + + S L +P+ E +S EW
Sbjct: 57 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLL-QVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFIC---AIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSA----NLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL----KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDDNS-QSKLAVHIPREEYMSSQEW 413
BLAST of von Willebrand factor A domain-containing protein 3A vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 183.341 bits (464), Expect = 1.255e-46 Identity = 109/289 (37.72%), Postives = 156/289 (53.98%), Query Frame = 3
Query: 3111 AVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLE-------------------KYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
AV +EE+++S++W+ KY LK+ LD ++SG RH + ++ LE K + AKYC + G+ H+Q + YS K L+ +R+EWL S+ +FG I E V IL+D S SM PH+ + L LI EQL + K N +AFN++ +R+RLV E++ SA W E L G+T+T AL ++D QGIYLLTDG+PD T+ VL ++ + ++PIHTISFNC D AN FL LAR + GR+H
Sbjct: 396 AVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQL-RHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIR-----LQYRLPIHTISFNCADLEANTFLCELARETGGRFH 678 HSP 2 Score: 118.627 bits (296), Expect = 1.618e-26 Identity = 91/286 (31.82%), Postives = 144/286 (50.35%), Query Frame = 3
Query: 1908 SIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKL----MEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRE-SG-----------IIESDDIRVLMAEIDLAVE 2717
++ + + ++ Y V+W DGS+ VH ++ + +L E++KL + +RI WL GSR +FGTI+E +V +++D+S S ++ + L LIQ+QL+ K K N +AF+ ++ L V E NL+ +W WL L C GS N L AL+ ++ + QGIYL T G PDQ + +++ I L + IHT+ FN D + + + LA T GRFH+F E SG ES+DI++L +E L +
Sbjct: 459 TLHQKLINAKYCDKFAHVKWKDGSL--VHVQMSS--DVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQF-------AIKDRNCQGIYLLTDGRPDQPTKTVLSQIR---LQYRLPIHTISFNCADLEANT---------------FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFD 715 HSP 3 Score: 88.9669 bits (219), Expect = 1.972e-17 Identity = 74/291 (25.43%), Postives = 132/291 (45.36%), Query Frame = 3
Query: 3120 PDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFP--------IVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKIS-YNIIAFNSQIRRFRERLVTPDESSCHSAIGW---TEHLVACGNTDTTKALLITLEDPRIQGIYLLT-DGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMF 3953
PD + ++S+ W+ K+ LK LD L E L+K + ++Y LFP NV ++ L EL + A+ Y +RLEWL S+R+FGVI E V I++D + I ++ + EQ+ R I+ +N+I + L+ + + + I W + A + + +AL+ + + +YL+T D D S E++ + V+ + K+P++ IS+NC+D +LK L M+ GR+H + ++ +
Sbjct: 47 PDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQEL-------ENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQI--RCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL------KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAY 322 HSP 4 Score: 80.4925 bits (197), Expect = 7.494e-15 Identity = 60/235 (25.53%), Postives = 110/235 (46.81%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISF-QDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMT---------EELMYTSNDIDLLLLEIERTQEVLEKIELMR 1355
Y ++ + + ++RI+W QGSR++FG + ++ +LID S + ISF +D L L+ EQL K IN F T +++ ++ + ++ G N + AL++ K+++ + L+ PDQ K ++ Q+ L LP H +S+ E ++ L +A + G +H ++ ++ E + S DI LL E + LEK+ +R
Sbjct: 496 YSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISAS---MEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVL---SQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLR 724 HSP 5 Score: 63.5438 bits (153), Expect = 1.094e-9 Identity = 74/293 (25.26%), Postives = 129/293 (44.03%), Query Frame = 3
Query: 1971 DGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLN---CSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPD-----------QQIE-PL------------MAYIEERVLGTDIKIHTVLFN--VDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEK 2762
DG NV A +L + Q+ L V+L +QR+ WLS+ SRR+FG I E V +I+D+ N + + +++ + +Q++ KFN+I L V++ NL + WL ++ + S NL+ AL + + +N + +YL T + +Q++ PL ++Y++ VL T + H+ LFN VD Y+ S + AN+ K + + GI +D + +EI+ A + + +IN EK
Sbjct: 110 DGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEAL-------IRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLL------------LKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEK 383 HSP 6 Score: 52.7582 bits (125), Expect = 2.687e-6 Identity = 87/370 (23.51%), Postives = 156/370 (42.16%), Query Frame = 3
Query: 525 SSEDWL-----KTHNLDALQL----------TIEDLISK---GKLGN---PRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDAN-LGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFM-----NLNCRV--IEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGS-CPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDL------LLLEIERTQEVLEKIELMRR--GIFS--NRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
SSE WL K NLD+ L D++ K + G+ P+ + G +N + + ++ + +L A+++Y +R++W SR++FG + + ++ID + N F + I + L+EQ+ N+ N L + + NL + + +I + +T S+ NL++AL + K + + LI D ++L V+QL +P + +SY + E S LK + ++ G +H Y E Y S+ +D LLL+ + + I +FS A INQI + IP+ + + S L +P+ E +S EW
Sbjct: 54 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLL-QVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFIC---AIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSA----NLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL----KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDDNS-QSKLAVHIPREEYMSSQEW 410
BLAST of von Willebrand factor A domain-containing protein 3A vs. Planmine SMEST
Match: SMESG000047774.1 (SMESG000047774.1) HSP 1 Score: 183.341 bits (464), Expect = 1.301e-46 Identity = 109/289 (37.72%), Postives = 156/289 (53.98%), Query Frame = 3
Query: 3111 AVIPDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLE-------------------KYVEAKYCAGLFPIVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKISYNIIAFNSQIRRFRERLVTPDESSCHSAIGWTEHLVACGNTDTTKALLITLEDPRIQGIYLLTDGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYH 3920
AV +EE+++S++W+ KY LK+ LD ++SG RH + ++ LE K + AKYC + G+ H+Q + YS K L+ +R+EWL S+ +FG I E V IL+D S SM PH+ + L LI EQL + K N +AFN++ +R+RLV E++ SA W E L G+T+T AL ++D QGIYLLTDG+PD T+ VL ++ + ++PIHTISFNC D AN FL LAR + GR+H
Sbjct: 399 AVHIPREEYMSSQEWLAKYGLKSRKLDFFDVLSGVCFRHCDGVVDVLEPPPVDKLDFMEQQNATLHQKLINAKYCDKFAHVKWKDGSLVHVQMSSDVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQL-RHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVLSQIR-----LQYRLPIHTISFNCADLEANTFLCELARETGGRFH 681 HSP 2 Score: 118.627 bits (296), Expect = 1.609e-26 Identity = 91/286 (31.82%), Postives = 144/286 (50.35%), Query Frame = 3
Query: 1908 SIGRMVTSSVYEKAMIQVEWPDGSVRNVHADLAQLFEYQKLLGEQVKL----MEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLNCSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPDQQIEPLMAYIEERVLGTDIKIHTVLFNVDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRE-SG-----------IIESDDIRVLMAEIDLAVE 2717
++ + + ++ Y V+W DGS+ VH ++ + +L E++KL + +RI WL GSR +FGTI+E +V +++D+S S ++ + L LIQ+QL+ K K N +AF+ ++ L V E NL+ +W WL L C GS N L AL+ ++ + QGIYL T G PDQ + +++ I L + IHT+ FN D + + + LA T GRFH+F E SG ES+DI++L +E L +
Sbjct: 462 TLHQKLINAKYCDKFAHVKWKDGSL--VHVQMSS--DVHRLYSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISASMEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQF-------AIKDRNCQGIYLLTDGRPDQPTKTVLSQIR---LQYRLPIHTISFNCADLEANT---------------FLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFD 718 HSP 3 Score: 88.9669 bits (219), Expect = 2.044e-17 Identity = 74/291 (25.43%), Postives = 132/291 (45.36%), Query Frame = 3
Query: 3120 PDKEEWITSKDWMKKYSLKNMGLDLLRLVSGPECRHEEALIIPLEKYVEAKYCAGLFP--------IVNVKGTRKHLQYTVTELNKYSVEAKKALIRYMKRLEWLMISSKRIFGVITETDVAILLDTSGSMTPHMPELILNLKALIWEQLFKRKIS-YNIIAFNSQIRRFRERLVTPDESSCHSAIGW---TEHLVACGNTDTTKALLITLEDPRIQGIYLLT-DGKPDNSTEIVLKNVQNIMSSRKTKVPIHTISFNCEDESANEFLKRLARMSNGRYHKVCHDYDIRMF 3953
PD + ++S+ W+ K+ LK LD L E L+K + ++Y LFP NV ++ L EL + A+ Y +RLEWL S+R+FGVI E V I++D + I ++ + EQ+ R I+ +N+I + L+ + + + I W + A + + +AL+ + + +YL+T D D S E++ + V+ + K+P++ IS+NC+D +LK L M+ GR+H + ++ +
Sbjct: 50 PDAKLQVSSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLLQVQQEL-------ENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQI--RCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL------KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAY 325 HSP 4 Score: 80.4925 bits (197), Expect = 8.523e-15 Identity = 60/235 (25.53%), Postives = 110/235 (46.81%), Query Frame = 3
Query: 681 YEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDANLGFGRVISF-QDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFMNLNCRVIEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGSCPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMT---------EELMYTSNDIDLLLLEIERTQEVLEKIELMR 1355
Y ++ + + ++RI+W QGSR++FG + ++ +LID S + ISF +D L L+ EQL K IN F T +++ ++ + ++ G N + AL++ K+++ + L+ PDQ K ++ Q+ L LP H +S+ E ++ L +A + G +H ++ ++ E + S DI LL E + LEK+ +R
Sbjct: 499 YSERMKLCLLAITRRIEWLRQGSRELFGTIMEDQVYILIDISAS---MEPHISFVKDKLYTLIQEQLRHKSKINFVAFNTKALPWRDRLVDVTEANLKSAWQWLEGLTCQGSTNTLSALQFAIKDRNCQGIYLLTDGRPDQPTKTVL---SQIRLQYRLPIHTISFNCADLEANTFLCELARETGGRFHYFNEISGGADCTNENELEAWESEDIKLLKSEYRLGFDSLEKVTKLR 727 HSP 5 Score: 63.5438 bits (153), Expect = 1.077e-9 Identity = 74/293 (25.26%), Postives = 129/293 (44.03%), Query Frame = 3
Query: 1971 DGSVRNVHADLAQLFEYQKLLGEQVKLMEQRITWLSTGSRRIFGTIIERKVILILDLSISNIKYLVHXXXXXXXXXXXXXXXXXXFNIIAFSNTISSFKAGLTVVNETNLQDSWSWLRSLN---CSGSRNLLGALKHVFENPVDSVHNDYAQGIYLFTSGVPD-----------QQIE-PL------------MAYIEERVLGTDIKIHTVLFN--VDDYDVSGTPIPSRYANITKTAEIMRMLAHSTKGRFHWFRESGIIESDDIRVLMAEIDLAVEYSRRTQQIINDYKEK 2762
DG NV A +L + Q+ L V+L +QR+ WLS+ SRR+FG I E V +I+D+ N + + +++ + +Q++ KFN+I L V++ NL + WL ++ + S NL+ AL + + +N + +YL T + +Q++ PL ++Y++ VL T + H+ LFN VD Y+ S + AN+ K + + GI +D + +EI+ A + + +IN EK
Sbjct: 113 DGLTFNVVAKKEKLLQVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFICAIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSANLVEAL-------IRASNNKENEALYLITEDLSSDGSREVLREKVKQLKIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLL------------LKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEK 386 HSP 6 Score: 52.373 bits (124), Expect = 3.027e-6 Identity = 87/370 (23.51%), Postives = 156/370 (42.16%), Query Frame = 3
Query: 525 SSEDWL-----KTHNLDALQL----------TIEDLISK---GKLGN---PRPDEQTGTAYNCLVYDDFIVTDYEYKLHMAIEMYSKRIKWYLQGSRKMFGFVSGSKLAVLIDSSDAN-LGFGRVISFQDNLLHLLDEQLFKKKSINIGYFGTNTKFLYQDFM-----NLNCRV--IEEIKESFSTMSSLGGCNLMQALKYVTKEKSIDEVLLILGS-CPDQEAKMLMYFVQQLLLGRDLPFHCVSYETQSEEVSSILKYIATISHGNYHRYSSMTEELMYTSNDIDL------LLLEIERTQEVLEKIELMRR--GIFS--NRASPYINQIAEELKNIPQSENLPKPISFNDPLKFEVPKFEPRTSSEW 1514
SSE WL K NLD+ L D++ K + G+ P+ + G +N + + ++ + +L A+++Y +R++W SR++FG + + ++ID + N F + I + L+EQ+ N+ N L + + NL + + +I + +T S+ NL++AL + K + + LI D ++L V+QL +P + +SY + E S LK + ++ G +H Y E Y S+ +D LLL+ + + I +FS A INQI + IP+ + + S L +P+ E +S EW
Sbjct: 57 SSEQWLNKFGLKASNLDSSSLYPRLGFARLEGFNDVLKKPIHSRYGDNLFPKHFREDGLTFNVVAKKEKLL-QVQQELENAVQLYQQRLEWLSSESRRLFGVIEEHCVTIIIDIKNKNKRDFDQFIC---AIERFLNEQIRCIAKFNLIRVQENKCQLSNNLLPVSKDNLANGIDWLWQIDRTSATNSA----NLVEALIRASNNKENEALYLITEDLSSDGSREVLREKVKQL----KIPLNIISYNCKDPEFISYLKCLVLMTGGRFHSYLFNLEVDAYESSPLDSENPKANLLLKKKVYGGSIGGIGTRNDCVAVFSEIEEAKALINQIKSLINQIPEKKGIYDDNS-QSKLAVHIPREEYMSSQEW 413 The following BLAST results are available for this feature:
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Human
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Human e!99) Total hits: 5
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Celegans
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Celegan e!99) Total hits: 0
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Fly
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Drosophila e!99) Total hits: 0
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Zebrafish
Analysis Date: 2016-08-08 (Schmidtea mediterranea smed_20140614 BLASTX Zebrafish e!99) Total hits: 1
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Xenopus
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Xenopus e!99) Total hits: 4
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Mouse
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX Mouse e!99) Total hits: 5
BLAST of von Willebrand factor A domain-containing protein 3A vs. UniProt/SwissProt
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI UniProt) Total hits: 4
BLAST of von Willebrand factor A domain-containing protein 3A vs. TrEMBL
Analysis Date: 2020-05-01 (Schmidtea mediterranea smed_20140614 BLASTX EMBL-EBI TrEMBL) Total hits: 5
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Cavefish
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Cavefish e!99) Total hits: 5
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Sea Lamprey
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Sea Lamprey e!99) Total hits: 3
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Yeast
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Yeast e!Fungi46) Total hits: 0
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Nematostella
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Nematostella e!Metazoa46) Total hits: 2
BLAST of von Willebrand factor A domain-containing protein 3A vs. Ensembl Medaka
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Medaka e!99) Total hits: 0
BLAST of von Willebrand factor A domain-containing protein 3A vs. Planmine SMEST
Analysis Date: 2020-05-08 (Schmidtea mediterranea smed_20140614 BLASTX Planmine SMEST) Total hits: 5
Analyses
This transcript is derived from or has results from the following analyses Sequences
The following sequences are available for this feature:
transcript sequence >SMED30034618 ID=SMED30034618|Name=von Willebrand factor A domain-containing protein 3A|organism=Schmidtea mediterranea sexual|type=transcript|length=4287bpback to top protein sequence of SMED30034618-orf-1 >SMED30034618-orf-1 ID=SMED30034618-orf-1|Name=SMED30034618-orf-1|organism=Schmidtea mediterranea sexual|type=polypeptide|length=1385bp MYRKDKVAVAVDSYKRKYSDDENEDSLQNNSNNIDKENESEKSSSDERNEback to top Annotated Terms
The following terms have been associated with this transcript:
InterPro
Analysis Name: Schmidtea mediteranean smed_20140614 Interproscan
Date Performed: 2020-05-01
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